Datasets

Nucleic Acid Drug Database

Website

DB is focused on nucleic acid drugs known as biopharmaceuticals and displayed approval drugs and information on three phases of clinical trial stage.

Dataset specifications

Tags
Drug/Chemical RNA Sequence Structure Journal article/Report/Bibliography
Provenance Original
Registration Submitted
Data provider
  • Molecular Profiling Research Center for Drug Discovery (molprof), The National Institute of Advanced Industrial Science and Technology (AIST)
Creator
  • Kazuhiko FukuiMolecular Profiling Research Center for Drug Discovery (molprof), The National Institute of Advanced Industrial Science and Technology (AIST)
  • Takayuki AmemiyaMolecular Profiling Research Center for Drug Discovery (molprof), The National Institute of Advanced Industrial Science and Technology (AIST)
  • Hiroshi KounoMolecular Profiling Research Center for Drug Discovery (molprof), The National Institute of Advanced Industrial Science and Technology (AIST)/Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science
Issued 2019-05-14
Licenses
  • Attribution-ShareAlike 2.1 Japan (CC BY-SA 2.1)
Version 2019-05-14
Download /download/#nadd
SPARQL Endpoint https://rdfportal.org/primary/sparql

Dataset statistics

Triples
948
Subjects
112
Properties
8
Objects
568
Classes
4

SPARQL example queries

Example 1

Run on Endpoint 
# がんをターゲットとする核酸医薬品の一覧の取得

PREFIX obo: <http://purl.obolibrary.org/obo/>
SELECT ?entry ?disease
FROM <http://purl.jp/bio/18/nadd/>
WHERE {
    ?entry obo:RO_0002606 ?disease FILTER ( ?disease = obo:MONDO_0005097 || ?disease = obo:MONDO_0005192 || ?disease = obo:MONDO_0005233 || ?disease = obo:MONDO_0005575 || ?disease = obo:MONDO_0007256 || ?disease = obo:MONDO_0008315 ) #Including cancer
}

Example 2

Run on Endpoint 
# ターゲット分子の立体構造が解かれている核酸医薬品の一覧の取得

PREFIX PDBr: <https://rdf.wwpdb.org/pdb/>
PREFIX sio: <http://semanticscience.org/resource/>
SELECT ?entry ?molecule
FROM <http://purl.jp/bio/18/nadd/>
WHERE {
    ?entry sio:SIO_010423 ?molecule FILTER REGEX ( str(?molecule), "pdb")
}