percent_inhibition
type: Class
subclass of: Measurement

Measurement
type: Class
subclass of: Quality
comment: Measured values and units.

1,1-diphenyl-2 picrylhydrazyl SC50
type: Class
subclass of: SC50
comment: Numbers in parentheses indicate the percentage of scavenging or inhibition at the indicated concentrations.

SC50
type: Class
subclass of: Concentration
comment: half-maximal scavenging concentration

Reactive oxygen species
type: Class
subclass of: Biological Target
comment: Reactive oxygen species are organic or inorganic chemicals that contain an oxygen atom with an unpaired electron. This unstable electron configuration causes these chemicals to be highly reactive with other molecules.

Biological Target
type: Class
comment: A biological target is a biopolymer such as a protein or nucleic acid whose activity can be modified by an external stimulus. A Chemopreventive agent has a Biological target in order to "hit" it and change its behavior in order to prevent a disease.
subclass of: Molecule

Cyp1AIC50
type: Class
comment: IC50 of Cyp1A
subclass of: IC50

IC50
type: Class
subclass of: Concentration
comment: half-maximal inhibitory concentration

Concentration
type: Class
comment: In chemistry, concentration is defined as the abundance of a constituent divided by the total volume of a mixture.
subclass of: Measurement

chemopreventionStudy
type: Class
comment: A Study related to Cancer Chemoprevention.
subclass of: Study

Study
type: Class
subclass of: GenericallyDependentContinuant
comment: A study is a collection of bioassays sharing a protocol

toxicityStudy
type: Class
comment: A Study related to the toxicity of e.g. a Chemopreventive Agent.
subclass of: Study

CD
type: Class
comment: Concentration required to double the specific activity of quinone reductase
subclass of: Concentration

Antioxidant
type: Class
comment: Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
subclass of: biological Mechanism

biological Mechanism
type: Class
subclass of: ProcessualEntity
comment: The way a Chemopreventive Agent acts on a Target in order to prevent disease (e.g Cancer)

HL60IC50.
type: Class
comment: Inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced superoxide anion radical generation in differentiated HL-60 cells (HL-60 assay). Numbers in parentheses indicate the percentage of scavenging or inhibition at the indicated concentrations.
subclass of: IC50

user_assay
type: Class
comment: A user defined assay.
subclass of: Bioassay

Bioassay
type: Class
subclass of: in_vivo_assay
comment: A Bioassay is a laboratory test or analysis of the biological activity of a substance (e.g. Chemopreventive agent) performed by studying its effect on an organism or in a test tube under controlled conditions. A Bioassay is part of an experiment that includes also other bioassays.

fractionation_guided
type: Class
comment: An in-vivo bioassay the uses fractionation.
subclass of: Bioassay

Virtual screening
type: Class
comment: Virtual Screening refers to the technique of performing a Biomedical experiment entirely in a computer via computer simulation.
subclass of: in_silico_assay

in_silico_assay
type: Class
comment: An In silico assay is performed on computer or via computer simulation.
subclass of: Assay

COX1IC50
type: Class
subclass of: IC50
comment: Cox-1 inhibition IC50 [µM]

in vitro bio assay
type: Class
comment: A Bioassay is a laboratory test or analysis of the biological activity of a substance (e.g. Chemopreventive agent) performed by studying its effect on an organism or in a test tube under controlled conditions. A Bioassay is part of an experiment that includes also other bioassays.
subclass of: in_vitro_assay

in_vitro_assay
type: Class
comment: An in vitro (Latin for within the glass) assay refers to the technique of performing an assay in a controlled environment outside of a living organism.
subclass of: Assay

Anti-metastatic Anti-agiogenic
type: Class
comment: Metastasis is a complex series of steps in which cancer cells leave the original tumor site and migrate to other parts of the body via the bloodstream or the lymphatic system. Malignant cells break away from the primary tumor and attach to and degrade proteins that make up the surrounding extracellular matrix (ECM). By degrading these proteins, cancer cells are able to breach the ECM and escape. The body resists metastasis by a variety of mechanisms through the actions of a class of proteins known as metastasis suppressors. One of the critical events required is the growth of new blood vessels from pre-existing vessels growth of a new network of blood vessels (Angiogenesis).
subclass of: biological Mechanism

IC
type: Class
comment: Maximum Inhibitory concentration
subclass of: Concentration

epigeneticsStudy
type: Class
comment: A Study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence.
subclass of: Study

in_vivo_assay
type: Class
comment: An In vivo (Latin for "within the living") refers to experimentation using a whole, living organism as opposed to a partial or dead organism.
subclass of: Assay

ScientificWorkflow
type: Class
subclass of: ProcessAggregate
comment: The Scientific workflow is a pipeline of connected components (in-silico tools, models) to perform an in silico experiment.

Disease
type: Class
subclass of: Disposition
comment: A Disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.

Molecule
type: Class
subclass of: Object
comment: The smallest particle of a substance that has all of the physical and chemical properties of that substance. Molecules are made up of one or more atoms. If they contain more than one atom, the atoms can be the same (an oxygen molecule has two oxygen atoms) or different (a water molecule has two hydrogen atoms and one oxygen atom). Biological molecules, such as proteins and DNA, can be made up of many thousands of atoms.

CancerType
type: Class
comment: Cancer has many cancer types modeled by this class
subclass of: Cancer

Cancer
type: Class
comment: A disease characterized by abnormal and uncontrolled cell division
subclass of: Disease

goURI
type: Class
comment: The Gene Ontology URI
subclass of: Resources

Resources
type: Class
subclass of: GenericallyDependentContinuant
comment: Links for resources related to the model.

iNOSIC50
type: Class
comment: Inhibition of iNOS induction A-IC50.
subclass of: IC50

Assay
type: Class
subclass of: ProcessualEntity
comment: Test performed either on material taken from the subject or on the whole initial subject, which produce qualitative or quantitative measurements (data).

chebiURI
type: Class
comment: The URI of chebi
subclass of: Resources

ORAC
type: Class
comment: Measurement of oxygen radical absorbance capacity. One ORAC unit equals the net protection produced by 1 µM Trolox.
subclass of: Measurement

PublishedWork
type: Class
subclass of: GenericallyDependentContinuant
comment: A printed or electronic work offered for distribution.

drugbankURI
type: Class
comment: The URI of drug bank
subclass of: Resources

Investigation
type: Class
subclass of: ProcessualEntity
comment: High-level concept to link related studies

pubmedURL
type: Class
comment: The pubmed URL
subclass of: Resources

ORACROO
type: Class
comment: A measurement, subclass of ORAC.
subclass of: ORAC

Natural source
type: Class
subclass of: Source
comment: A Natural Source is a substance found in nature that usually has a pharmacological or biological activity. A Chemopreventive agent may be contained into a Natural Source.

Source
type: Class
subclass of: Object
comment: The source of a Chemopreventive agent can be either Natural (e.g. pomegranate) or Synthetic (e.g. a drug)

ORACOH
type: Class
comment: A measurement, subclass of ORAC.
subclass of: ORAC

Clinical trial
type: Class
subclass of: in_vivo_assay
comment: A Clinical trial is a research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. Interventions include but are not restricted to drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioral treatments, process-of-care changes, and preventive care.

Pathway
type: Class
subclass of: ProcessualEntity
comment: A Pathways is a set or series of interactions, often forming a network, which biologists have found useful to group together for organizational, historic, biophysical, or other reasons. The Chemopreventive agent affects a Biological target in order to brake the series of interactions that leads to a Disease (i.e. cancer). Instances can come from any of the pathway databases. Instances should be indexed with those URI.

mechanism_based
type: Class
comment: An in vivo bioassay based on mechanosms.
subclass of: Bioassay

Sugar
type: Class
subclass of: Biological Target
comment: Any member of a class of edible, crystalline carbohydrates (mainly sucrose, lactose and fructose) characterised by a sweet flavour; a loose term applied to monosaccharides, disaccharides, trisaccharides and oligosaccharides, in contrast to complex carbohydrates such as polysaccharides.

Protocol
type: Class
subclass of: GenericallyDependentContinuant
comment: A protocol is an information entity which is a set of instructions that describe how an Study is done.

enzymeInduction
type: Class
subclass of: chemopreventionStudy
comment: e.g. NAD(P)H:quinone reductase (quinone reductase, QR) activity

Experimental factor
type: Class
subclass of: Object
comment: Experimental factors are the variable aspect of an experiment design which can be used to describe an experiment, or set of experiments, in an increasingly detailed manner.

ChemopreventiveAgent
type: Class
subclass of: Molecule
comment: A Chemopreventive agent is a Molecule that has shown some evidence that it may be able to prevent or delay the development of a specific Disease (e.g. cancer) by interfering with a Biological target. For example - cancer chemopreventive agents are used to inhibit, delay, or reverse carcinogenesis. A Chemopreventive agent can be tested into an Experiment and can be contained into a Natural source or a Drug. References to a Chemopreventive agent can be found into a Publication.

Databases
type: Class
comment: Links Databases related to CanCO e.g. kegg, chebi, pubmed, pubchem etc.
subclass of: Resources

OCDIC50
type: Class
subclass of: IC50
comment: Inhibition of ODC induction IC50 [µM]

QRIC50
type: Class
comment: IC50 of Quinone Reductase
subclass of: IC50

Organism
type: Class
subclass of: Experimental factor
comment: A living entity.

carcinogenActivating
type: Class
subclass of: chemopreventionStudy
comment: e.g. Inhibition of cytochrome P450 (Cyp) 1A activity

NucleicAcid
type: Class
subclass of: Biological Target
comment: Nucleic Acid are a family of macromolecules, composed of various moieties: purines, pyrimidines, phosphoric acid, and a pentose, either d-ribose or d-deoxyribose. Nucleic acids as DNA or RNA is found in the chromosomes, nucleoli, mitochondria, and cytoplasm of all cells, and in viruses. Nucleic acids are the major players in controlling cellular function and heredity.

Macromolecule
type: Class
comment: Macromolecules are molecules made of many smaller molecules
subclass of: Molecule

Protein
type: Class
subclass of: Biological Target
comment: A Protein is a group of complex organic macromolecules composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Proteins are fundamental genetically encoded components of living cells with specific structures and functions dictated by amino acid sequence.

keggURI
type: Class
comment: The Kegg URI
subclass of: Resources

Antiinflammatory
type: Class
comment: Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation.
subclass of: biological Mechanism

Estrogenic Activity
type: Class
comment: Compounds having similar structure with steroid hormones, like estrogens, can bind to and activate estrogen receptors (ER) which in turn modulate the expression of many genes.
subclass of: biological Mechanism

Toxicity
type: Class
subclass of: Quality
comment: Toxicity is a quality of a chemical substance which indicates the capacity to cause injury to an organism in a dose dependent manner.

BioMaterial
type: Class
subclass of: Experimental factor
comment: A biomaterial is any matter, surface, or construct that interacts with biological systems

dbpediaURI
type: Class
comment: The URI of dppedia
subclass of: Resources

Antiproliferative
type: Class
comment: Antiproliferative agents work to block the proliferative phase of acute cellular rejection.
subclass of: biological Mechanism

Organ
type: Class
subclass of: Object
comment: A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues. An organ is part of an anatomic system or a body region. Representative examples include the heart, lung, liver, spleen, and uterus.

pubchemURI
type: Class
comment: The pubchem URI
subclass of: Resources

Apoptotic
type: Class
comment: Apoptosis is programmed cell death, a normal component of the development and health of multicellular organisms. Cells die in response to a variety of stimuli and during apoptosis they do so in a controlled, regulated fashion. This makes apoptosis distinct from another form of cell death called necrosis in which uncontrolled cell death leads to lysis of cells, inflammatory responses and, potentially, to serious health problems. Upon receiving specific signals instructing the cells to undergo apoptosis a number of distinctive changes occur in the cell. A family of proteins known as caspases are typically activated in the early stages of apoptosis. These proteins breakdown or cleave key cellular components that are required for normal cellular function including structural proteins in the cytoskeleton and nuclear proteins such as DNA repair enzymes. The caspases can also activate other degradative enzymes such as DNases, which begin to cleave the DNA in the nucleus.
subclass of: biological Mechanism

iNOSTIC50
type: Class
subclass of: IC50
comment: Inhibition of iNOS induction A-IC50 [µM]a T-IC50 [µM]b

Dataset
type: Class
comment: The URLs of SPARQL endpoints.
subclass of: Resources

Drug
type: Class
subclass of: Synthetic source
comment: A Drug is any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. A Chemopreventive agent may be contained into a drug.

Synthetic source
type: Class
subclass of: Source
comment: A Synthetic Source is constructed and has a pharmacological or biological activity. A Chemopreventive agent may be contained into a Synthetic Source.

xanthine oxidase SC50
type: Class
comment: Numbers in parentheses indicate the percentage of scavenging or inhibition at the indicated concentrations.
subclass of: SC50

chemSpiderURL
type: Class
comment: The URL of chemspider
subclass of: Resources

pubmedURI
type: Class
comment: The pubmed URI
subclass of: Resources

Lipid
type: Class
subclass of: Biological Target
comment: A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides.

ResearchStatement
type: Class
subclass of: GenericallyDependentContinuant
comment: A Research Statement is a declarative sentence supported by a specific Publication.

Forum post
type: Class
subclass of: GenericallyDependentContinuant
comment: A Forum Post is related to a Published Work and contains comments about this specific Publication. It allows the discussion and the exchange of ideas related to the Published Work.

Person
type: Class
subclass of: Object
subclass of: Person

Cell line
type: Class
comment: A cell line is a cell factor which describes a population of cells cultured in vitro that are descended through one or more generations (and possible sub-cultures) from a single primary culture which was originally derived from part of an organism. The cells of such a population share common characteristics.
subclass of: Experimental factor

hasAuthor
type: ObjectProperty
domain: Study
domain: PublishedWork
comment: Correlates a Published work or a Forum Post with the Person that has written them.
domain: Forum post
range: Person

hasSource
type: ObjectProperty
comment: Correlates a Chemopreventive Agent with the sources where it is available or from where it originates.
domain: ChemopreventiveAgent
range: Source

has disease location
type: ObjectProperty
domain: Disease
range: Organ

measure
type: ObjectProperty
comment: Indicate the measurements made during a Study.
range: Measurement
domain: Study

uriLookupEndpoint
type: ObjectProperty
domain: Resources

contain molecule
type: ObjectProperty
range: Molecule
comment: Correlates a Source (e.g. Natural or Synthetic) with the Molecules it contains
domain: Source

used_protocol
type: ObjectProperty
comment: Indicate the Protocol used by a Study.
range: Protocol
range: Restriction
  on property: used_protocol
  some values from: Protocol
domain: Restriction
  some values from: Bioassay
  on property: used_protocol
domain: Study

containStudy
type: ObjectProperty
comment: Indicate the Studies contained into an Investigation.
domain: Investigation
range: Study

isTreatedBy
type: ObjectProperty
comment: Correlates a Disease with the Chemopreventive Agent that can treat it.
range: ChemopreventiveAgent
domain: Disease

containsTarget
type: ObjectProperty
range: Biological Target
comment: Correlates a Pathway with the Biological Targets (e.g. protein) it contains.
domain: Pathway

topic
type: ObjectProperty

use factor
type: ObjectProperty
range: Experimental factor
comment: Correlates an Protocol with the Experimental Factors used.
domain: Protocol

use workflow
type: ObjectProperty
comment: Correlates an In Silico Experiment with the Scientific Workflow used.
domain: in_silico_assay
range: ScientificWorkflow

naturalVsSynthetic
type: ObjectProperty
range: Synthetic source
range: Natural source
domain: Source
comment: Indicate whether a Source is Natural or Synthetic.

hasTarget
type: ObjectProperty
range: Biological Target
domain: biological Mechanism
comment: Indicate the target of biological mechanism in order to prevent cancer.

hasBiologicalMechanism
type: ObjectProperty
comment: Indicate the Biological Mechanisms that has a Chemopreventive Agent.
domain: ChemopreventiveAgent
range: biological Mechanism

referenceTo
type: ObjectProperty
domain: PublishedWork
range: PublishedWork
comment: Correlates a Published work with other Published Work it references.

used_organism
type: ObjectProperty
comment: Indicate the Organisms used by an experimental Protocol.
range: Organism
sub property of: use factor
domain: Protocol

induce prevent
type: ObjectProperty
range: Biological Target
comment: Correlates a Chemopreventive Agent with the Biological Target it affects.
domain: ChemopreventiveAgent

used_cma
type: ObjectProperty
comment: Indicate the Chemopreventive Agents used by an Assay.
range: Restriction
  on property: used_cma
  some values from: ChemopreventiveAgent
domain: Restriction
  some values from: Bioassay
  on property: used_cma

hasToxicity
type: ObjectProperty
comment: Indicates the Toxicity of a Chemopreventive Agent.
domain: ChemopreventiveAgent
range: Toxicity

referredIntoPublication
type: ObjectProperty
comment: Correlated a Protocol or a Chemopreventive Agent with a Published work where the Protocol/Chemopriventive agent is described
domain: ChemopreventiveAgent
range: PublishedWork

part_of
type: ObjectProperty
comment: Indicate the Study that a Bioassay is part of.
range: Restriction
  some values from: Study
  on property: part_of
domain: Restriction
  some values from: Bioassay
  on property: part_of

affectPathway
type: ObjectProperty
domain: ChemopreventiveAgent
comment: Correlates a Chemopreventive Agent with the Pathways it affects.
range: Pathway

hasStatement
type: ObjectProperty
range: ResearchStatement
comment: Correlates a Published work with the Expressions (i.e. scientific statements) it contains.
domain: PublishedWork

containsOrgan
type: ObjectProperty
comment: Relates an Organism with the Organs it contains.
domain: Organism
range: Organ

hasToxicalConcentration
type: ObjectProperty
range: Concentration
comment: Indicates the concentration that is toxical.
domain: Toxicity

interact with
type: ObjectProperty
range: Biological Target
comment: Correlates a Drug with the biological Targets it interacts with.
domain: Drug

hasInput
type: ObjectProperty
range: Biological Target
comment: Defines the input of an Assay.
domain: Assay
range: Molecule

related to disese
type: ObjectProperty
comment: Correlates a Pathway with the Disease it is related
domain: Pathway
range: Disease

type
type: ObjectProperty
range: chemopreventionStudy
domain: Study

sameAs
type: ObjectProperty

commented in
type: ObjectProperty
comment: A Published work can be commented in a Formum post as part of a discussion related to the specific Published work.
domain: PublishedWork
range: Forum post

coOperateWith
type: ObjectProperty
comment: Correlates the Chemopreventive agents that can cooperate to prevent a cancer type.
domain: ChemopreventiveAgent
range: ChemopreventiveAgent

identify
type: ObjectProperty
comment: Indicate the Chemopreventive Agents that have been identified during an Assay.
domain: Assay
range: ChemopreventiveAgent

describedInPublication
type: ObjectProperty
domain: Investigation
domain: Protocol
range: PublishedWork
comment: Correlates an Investigation with a Published work that describes the results of the Investigation.

containAssay
type: ObjectProperty
domain: Study
range: Assay
comment: Correlates a Study with the Assays it contains

activity
type: DatatypeProperty
comment: The biological activity of a compound.
range: string

hasHypothesis
type: DatatypeProperty
comment: The Hypothesis of a Research Statement.
range: string
domain: ResearchStatement

publication
type: DatatypeProperty
range: string

publicationNumber
type: DatatypeProperty
range: string
comment: How many times has this compound been cited in the literature?

targetOrgan
type: DatatypeProperty
range: string
comment: Indicate whether there is a known target orgain for this chemopreventative agent

MDLmolfile
type: DatatypeProperty
range: string
comment: If you have an MDL Molfile for this component, insert it here

common name
type: DatatypeProperty
comment: The common name of a Source, Natural or Synthetic.
range: string
domain: Source

structuralKey
type: DatatypeProperty
range: string

hasCitation
type: DatatypeProperty
comment: The citation of the Published work (e.g. the Journal and the year of publication).
range: string
domain: PublishedWork

hasClaim
type: DatatypeProperty
comment: The Claim of a Research Statement.
range: string
domain: ResearchStatement

source
type: DatatypeProperty
range: string
comment: If this compound is normally found in a natural substatnce, indicate which in the domain

chemopreventionMechanism
type: DatatypeProperty
comment: Indicate the chemoprevention mechanism of a compound.
sub property of: actionMechanism

actionMechanism
type: DatatypeProperty
domain: Thing
comment: What is the action mechanism of the component?

affiliation
type: DatatypeProperty
range: string
domain: Person

hasComment
type: DatatypeProperty
domain: Forum post
range: string
comment: The comment of a forum post.

level
type: DatatypeProperty
comment: Indicates the level of toxicity.
range: string
domain: Toxicity

NAD(P)H:quinone reductase (quinone reductase, QR) activity
type: DatatypeProperty
sub property of: publicationNumber

hasCellularLocation
type: DatatypeProperty
comment: The cellular location where a Protein can be found.
range: string
domain: Protein

connectionTable
type: DatatypeProperty
comment: If you have a connection table for this chemical component, indicate it here.

hashedFingerprint
type: DatatypeProperty

efficacyInVivo
type: DatatypeProperty
comment: In this chemopreventative agent has been tested in vivo, what was the measured efficacy?

hasSequence
type: DatatypeProperty
domain: NucleicAcid
domain: Protein
range: string
comment: The sequence of ta Nucleid acid or Protein.

accessRights
type: DatatypeProperty
comment: The access rights of a Study.
range: boolean
domain: Study

input
type: DatatypeProperty

description
type: DatatypeProperty
comment: A lexical definition of a concept.
domain: Disease
domain: Investigation
domain: biological Mechanism
range: string
domain: Pathway
domain: Assay
domain: ScientificWorkflow
domain: Protocol
domain: ResearchStatement
domain: Experimental factor
domain: Study
domain: Molecule

cytochrome P450 (Cyp) 1A activity
type: DatatypeProperty
sub property of: activity

InChl
type: DatatypeProperty
range: string

antiOxidantActivity
type: DatatypeProperty
sub property of: activity
comment: Does this compound have antioxidative properties?

percentageValue
type: DatatypeProperty
comment: The value of the percentage
range: float
domain: percent_inhibition

used_cellLine
type: DatatypeProperty
comment: Indicate the cell lines used by an experimental Protocol.
sub property of: use factor
domain: Protocol
type: ObjectProperty

hasFormula
type: DatatypeProperty
domain: Molecule
comment: The chemical formula of the Molecule.
range: string

hasStatus
type: DatatypeProperty
comment: Indicate the status of a Published work
domain: PublishedWork
range: string

pathwayMap
type: DatatypeProperty
comment: The map (image representation) of a Pathway.
range: string
domain: Pathway

has abstract
type: DatatypeProperty
domain: PublishedWork
range: string
comment: The abstrac of a Published work.

diagram2D
type: DatatypeProperty
comment: If you have a link to an image with the 2D representation of this molecular, indicate its URL here

hasDate
type: DatatypeProperty
domain: Forum post
range: date
comment: The date the Forum post has been made.

toxicConcentration
type: DatatypeProperty
range: string
comment: If toxic, at which concentration has it been deemed toxic?

cellType
type: DatatypeProperty
domain: Toxicity
range: string
comment: Indicate the cell type of the Toxicity

title
type: DatatypeProperty
range: string
domain: Protocol
domain: Pathway
domain: Experimental factor
domain: Study
domain: Assay
domain: Investigation
domain: PublishedWork
comment: The title of concept.
domain: ScientificWorkflow
domain: biological Mechanism
domain: Disease
domain: Molecule

pathwayOrder
type: DatatypeProperty
range: string
comment: The order of action in a Pathway.
domain: Pathway

PDB_id
type: DatatypeProperty
domain: Thing
range: string
comment: If you know the PDB Id of this component, insert it here.

SMILESnotation
type: DatatypeProperty
domain: Molecule
range: string
comment: If you have the SMILES notation for this agent, insert it here.

output
type: DatatypeProperty

pathwayAction
type: DatatypeProperty
comment: Which metabolic pathways is this agent know to affect?

published
type: DatatypeProperty
range: boolean
comment: Has this been component been published before? Answer yes or no.

molecularWeight
type: DatatypeProperty
domain: Molecule
comment: The molecular weight of a Molecule.
range: integer

species
type: DatatypeProperty
comment: ??
range: string
domain: Toxicity

induceDifferentiation
type: DatatypeProperty
comment: Indicates if a chemopreventive agents acts by inducing cell differentiation.
range: boolean
domain: ChemopreventiveAgent

size
type: DatatypeProperty
comment: The size of a Molecule.
domain: Molecule
range: integer

has procedure
type: DatatypeProperty
comment: The procedure defined by the Protocol.
range: string
domain: Protocol

hasPublicationType
type: DatatypeProperty
comment: The type of publication, e.g. journal, paper etc.
range: string
domain: PublishedWork

inchi
type: DatatypeProperty
range: string
equivalent property: InChl

toxicity
type: DatatypeProperty
comment: false
range: boolean

drugbank sparql endpoint
type: Dataset
type: NamedIndividual

linked life data sparql endpoint
type: Dataset
type: NamedIndividual

drugbank
type: Databases
type: NamedIndividual

dbpedia sparql endpoint
type: Dataset
type: NamedIndividual

kegg spaql endpoint
type: Dataset
type: NamedIndividual

chebi sparql endpoint
type: Dataset
type: NamedIndividual

go sparql endpoint
type: Dataset
type: NamedIndividual