human anatomy
type: Ontology
version IRI: http://www.lungmap.net/ontologies/human_anatomy/1.0.1
contributor: Gail H. Deutsch
contributor: Huaqin Pan
contributor: NHLBI Molecular Atlas of Lung Development Program Consortium Ontology Subcommittee
contributor: Susan E Wert

part of
type: ObjectProperty
inverse of: BFO_0000051
type: TransitiveProperty
has db xref: BFO:0000050

located_in
type: ObjectProperty
has db xref: RO:0001025

continuous_with
type: ObjectProperty
type: SymmetricProperty
has db xref: RO:0002150

develops_from
type: ObjectProperty
sub property of: RO_0002254
inverse of: RO_0002203
type: TransitiveProperty
property chain axiom: part of
has db xref: RO:0002202

adjacent_to
type: ObjectProperty
type: SymmetricProperty
has db xref: RO:0002220

interalveolar septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolus of lung
has db xref: LMMA:00002
has db xref: UBERON:0004893
id: LMHA:00002
display: true
has domain: anatomy

matrix fibroblast
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar interstitial cell
has db xref: CL:0000057
has db xref: LMMA:00007
id: LMHA:00007
definition: A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with Branching_parting processes; appears fusiform or spindle-shaped.
display: true
has domain: cell
synonym: matrix synthesizing fibroblast

right lower lobe alveolar parenchyma
type: Class
subclass of: right lung lower lobe
id: LMHA:00020
display order: 3
has domain: anatomy

right lower lobe bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobe
has db xref: UBERON:0012059
id: LMHA:00021
display order: 2
has domain: anatomy

right lower lobe hilum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobe
has db xref: LMMA:00603
id: LMHA:00022
display order: 1
has domain: anatomy

right lower lobe visceral pleura
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobe
id: LMHA:00028
display order: 4
has domain: anatomy

right middle lobe alveolar parenchyma
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobe
id: LMHA:00029
display order: 3
has domain: anatomy

right middle lobe bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobe
has db xref: UBERON:0012068
id: LMHA:00030
display order: 2
has domain: anatomy

right middle lobe hilum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobe
id: LMHA:00031
display order: 1
has domain: anatomy

right middle lobe visceral pleura
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobe
id: LMHA:00037
display order: 4
has domain: anatomy

right upper lobe alveolar parenchyma
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobe
has db xref: FMA:31241
has db xref: LMMA:00038
id: LMHA:00038
display order: 3
has domain: anatomy

right upper lobe bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobe
has db xref: LMMA:00039
has db xref: UBERON:0005681
id: LMHA:00039
display order: 2
has domain: anatomy

right upper lobe hilum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobe
has db xref: LMMA:00605
id: LMHA:00040
display order: 1
has domain: anatomy

right upper lobe visceral pleura
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobe
has db xref: LMMA:00046
id: LMHA:00046
display order: 4
has domain: anatomy

submucosal gland
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal submucosa
subclass of: Restriction
  on property: part of
  some values from: bronchial submucosa
has db xref: LMMA:00047
has db xref: UBERON:0011148
id: LMHA:00047
has domain: anatomy

adipocyte
type: Class
subclass of: Restriction
  on property: part of
  some values from: adipose tissue
has db xref: CL:0000136
has db xref: LMMA:00054
id: LMHA:00054
definition: A connective tissue cell specialized to synthesize and store fat, primarily in the form of triglycerides.
has domain: cell

adipose tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial adventitia
subclass of: Restriction
  on property: part of
  some values from: tracheal adventitia
has db xref: FMA:20110
has db xref: LMMA:00055
id: LMHA:00055
has domain: tissue

alveolar capillary bed
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar duct wall
subclass of: Restriction
  on property: part of
  some values from: alveolar septal crest
subclass of: Restriction
  on property: part of
  some values from: primary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: secondary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar alveolus
has db xref: LMMA:00060
id: LMHA:00060
display: true
has domain: anatomy
synonym: alveolar capillary network

alveolar capillary endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar capillary bed
has db xref: LMMA:00061
id: LMHA:00061
has domain: anatomy

pulmonary alveolar duct
type: Class
subclass of: left upper lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right lower lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right middle lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right upper lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: left lower lobe alveolar parenchyma
has db xref: FMA:7341
has db xref: LMMA:00062
id: LMHA:00062
definition: The respiratory conducting tubes distal to the terminal bronchiole that lead to the alveolar sacs and the alveoli.
display: true
has domain: anatomy
synonym: alveolar duct
synonym: respiratory alveolar duct

alveolar duct lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary alveolar duct
has db xref: LMMA:00063
id: LMHA:00063
has domain: anatomy

alveolar duct wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary alveolar duct
has db xref: FMA:84476
has db xref: LMMA:00064
id: LMHA:00064
has domain: anatomy

alveolar epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar duct wall
subclass of: Restriction
  on property: part of
  some values from: alveolar septal crest
subclass of: Restriction
  on property: part of
  some values from: primary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: secondary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar alveolus
has db xref: FMA:63915
has db xref: LMMA:00065
id: LMHA:00065
display: true
has domain: anatomy

alveolar interstitial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar interstitial tissue
has db xref: LMMA:00066
id: LMHA:00066
definition: A mesenchymal-derived connective tissue cell located in the interstitial space (interstitium or connective tissue compartment) of the alveolar septum (wall).
has domain: cell
synonym: alveolar connective tissue cell
synonym: alveolar mesenchymal cell
synonym: alveolar stromal cell

alveolar interstitial tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar duct wall
subclass of: Restriction
  on property: part of
  some values from: alveolar septal crest
subclass of: Restriction
  on property: part of
  some values from: primary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: secondary alveolar septum
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar alveolus
has db xref: LMMA:00067
id: LMHA:00067
display: true
has domain: anatomy
synonym: alveolar connective tissue
synonym: alveolar interstitium
synonym: alveolar mesenchyme
synonym: alveolar stroma

alveolar lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolus of lung
has db xref: LMMA:00068
id: LMHA:00068
has domain: anatomy

alveolar septal crest
type: Class
subclass of: Restriction
  on property: part of
  some values from: interalveolar septum
has db xref: LMMA:00071
id: LMHA:00071
display: true
display order: 2
has domain: anatomy
synonym: alveolar septal ridge
synonym: secondary septal ridge
comment: primary alveolar septum gives rise to the alveolar septal crest, which develops into secondary alveolar septum

alveolus of lung
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right middle lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right upper lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: left lower lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: left upper lobe alveolar parenchyma
has db xref: EFO:0001985
has db xref: EMAPA:32682
has db xref: FMA:7318
has db xref: LMMA:00072
has db xref: MA:0000420
has db xref: UBERON:0002299
id: LMHA:00072
display: true
has domain: anatomy
synonym: alveoli
synonym: alveolus
synonym: alveolus pulmonis
synonym: lung alveolus
synonym: pulmonary alveolus
synonym: respiratory alveoli
synonym: respiratory alveolus

arteriole endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica intima
has db xref: LMMA:00078
has db xref: UBERON:0001916
id: LMHA:00078
has domain: tissue

artery endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica intima
has db xref: LMMA:00081
has db xref: UBERON:0001917
id: LMHA:00081
has domain: tissue

B lymphocyte
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: part of
  some values from: paracortex
subclass of: Restriction
  on property: part of
  some values from: mantle zone
subclass of: Restriction
  on property: part of
  some values from: germinal center
subclass of: Restriction
  on property: part of
  some values from: marginal zone
subclass of: Restriction
  on property: part of
  some values from: bronchus-associated lymphoid tissue
subclass of: Restriction
  on property: part of
  some values from: medullary cord
has db xref: CL:0000236
has db xref: LMMA:00086
id: LMHA:00086
HTC code: BCL
has domain: cell
synonym: B cell

basal cell
type: Class
subclass of: bronchial epithelial cell
subclass of: tracheal epithelial cell
subclass of: submucosal gland duct epithelial cell
has db xref: CL:0000646
has db xref: LMMA:00087
id: LMHA:00087
definition: An epithelial cell located at the base, or basal side, of the epithelium, in direct contact with the underlying basement membrane. These are small polyhedral cells with a large nucleus, relatively little cytoplasm and few organelles. They are undifferentiated, self-renewing, multipotent, progenitor (stem) cells for other epithelial cell types in the airway.
display: true
has domain: cell

basement membrane
type: Class
subclass of: Restriction
  on property: part of
  some values from: submucosal gland
subclass of: Restriction
  on property: part of
  some values from: alveolar capillary endothelium
subclass of: Restriction
  on property: part of
  some values from: alveolar epithelium
subclass of: Restriction
  on property: part of
  some values from: arteriole endothelium
subclass of: Restriction
  on property: part of
  some values from: artery endothelium
subclass of: Restriction
  on property: part of
  some values from: bronchial epithelium
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar epithelium
subclass of: Restriction
  on property: part of
  some values from: tracheal epithelium
subclass of: Restriction
  on property: part of
  some values from: vein endothelium
subclass of: Restriction
  on property: part of
  some values from: venule endothelium
subclass of: Restriction
  on property: part of
  some values from: visceral mesothelium
subclass of: Restriction
  on property: part of
  some values from: lymphatic endothelium
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar epithelium
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar epithelium
subclass of: Restriction
  on property: adjacent_to
  some values from: alveolar epithelium
has db xref: FMA:63872
has db xref: LMMA:00089
id: LMHA:00089
has domain: tissue

basophil
type: Class
subclass of: granulocyte
has db xref: CL:0000767
has db xref: LMMA:00090
id: LMHA:00090
has domain: cell
synonym: basophilic granulocyte
synonym: basophilic leukocyte

bronchial adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchus wall
has db xref: LMMA:00094
id: LMHA:00094
display order: 3
has domain: anatomy

bronchial arteriole
type: Class
subclass of: bronchial blood vessel
has db xref: LMMA:00095
id: LMHA:00095
display order: 2
has domain: anatomy

bronchial arteriole tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole
has db xref: LMMA:00096
id: LMHA:00096
has domain: anatomy

bronchial arteriole tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole
has db xref: LMMA:00097
id: LMHA:00097
has domain: anatomy

bronchial artery
type: Class
subclass of: bronchial blood vessel
has db xref: LMMA:00098
has db xref: UBERON:0002040
id: LMHA:00098
display order: 1
has domain: anatomy

bronchial artery tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial artery
has db xref: LMMA:00099
id: LMHA:00099
has domain: anatomy

bronchial artery tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial artery
has db xref: LMMA:00100
id: LMHA:00100
has domain: anatomy

bronchial epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial mucosa
has db xref: LMMA:00101
has db xref: UBERON:0002031
id: LMHA:00101
display: true
has domain: tissue

bronchial smooth muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial mucosa
subclass of: Restriction
  on property: part of
  some values from: bronchial cartilaginous ring
has db xref: LMMA:00482
has db xref: UBERON:0004242
id: LMHA:00103
display: true
has domain: anatomy

bronchial blood vessel
type: Class
subclass of: respiratory vascular system
has db xref: LMMA:00104
id: LMHA:00104
has domain: anatomy

bronchial vein
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial blood vessel
has db xref: LMMA:00105
has db xref: UBERON:0001592
id: LMHA:00105
display order: 4
has domain: anatomy

bronchial vein tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial vein
has db xref: LMMA:00106
id: LMHA:00106
has domain: anatomy

bronchial vein tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial vein
has db xref: LMMA:00107
id: LMHA:00107
has domain: anatomy

bronchial vein tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial vein
has db xref: LMMA:00108
id: LMHA:00108
has domain: anatomy

bronchial venule
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial blood vessel
has db xref: LMMA:00109
id: LMHA:00109
display order: 5
has domain: anatomy

bronchial venule tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial venule
has db xref: LMMA:00110
id: LMHA:00110
has domain: anatomy

bronchial venule tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial venule
has db xref: LMMA:00111
id: LMHA:00111
has domain: anatomy

bronchial venule tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial venule
has db xref: LMMA:00112
id: LMHA:00112
has domain: anatomy

bronchiolar adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar wall
id: LMHA:00114
has domain: anatomy
analogous to: LMMA:00525

bronchus
type: Class
has db xref: EMAPA:32689
has db xref: FMA:7409
has db xref: LMMA:00120
has db xref: MA:0000436
has db xref: UBERON:0002185
id: LMHA:00120
display: true
display order: 2
has domain: anatomy

bronchus lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung main bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung main bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: left anterior bronchus
subclass of: Restriction
  on property: part of
  some values from: left anterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: left apical bronchus
subclass of: Restriction
  on property: part of
  some values from: inferior lingular bronchus
subclass of: Restriction
  on property: part of
  some values from: left lateral basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right lateral bronchus
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right anterior basal segmental bronchus
subclass of: Restriction
  on property: part of
  some values from: medial basal bronchus
subclass of: Restriction
  on property: part of
  some values from: medial bronchus
subclass of: Restriction
  on property: part of
  some values from: left posterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: left posterior bronchus
subclass of: Restriction
  on property: part of
  some values from: left lower lobe superior bronchus
subclass of: Restriction
  on property: part of
  some values from: superior lingular bronchus
subclass of: Restriction
  on property: part of
  some values from: right upper lobe anterior bronchus
subclass of: Restriction
  on property: part of
  some values from: right apical bronchus
subclass of: Restriction
  on property: part of
  some values from: right lateral basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right posterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right lower lobe superior bronchus
subclass of: Restriction
  on property: part of
  some values from: right posterior bronchus
has db xref: LMMA:00123
has db xref: UBERON:0012083
id: LMHA:00123
has domain: anatomy

bronchus wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchus
subclass of: Restriction
  on property: part of
  some values from: left lung main bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung main bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: left anterior bronchus
subclass of: Restriction
  on property: part of
  some values from: left anterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: left apical bronchus
subclass of: Restriction
  on property: part of
  some values from: inferior lingular bronchus
subclass of: Restriction
  on property: part of
  some values from: left lateral basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right lateral bronchus
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobar bronchus
subclass of: Restriction
  on property: part of
  some values from: right anterior basal segmental bronchus
subclass of: Restriction
  on property: part of
  some values from: medial basal bronchus
subclass of: Restriction
  on property: part of
  some values from: medial bronchus
subclass of: Restriction
  on property: part of
  some values from: left posterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: left posterior bronchus
subclass of: Restriction
  on property: part of
  some values from: left lower lobe superior bronchus
subclass of: Restriction
  on property: part of
  some values from: superior lingular bronchus
subclass of: Restriction
  on property: part of
  some values from: right upper lobe anterior bronchus
subclass of: Restriction
  on property: part of
  some values from: right apical bronchus
subclass of: Restriction
  on property: part of
  some values from: right lateral basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right posterior basal bronchus
subclass of: Restriction
  on property: part of
  some values from: right lower lobe superior bronchus
subclass of: Restriction
  on property: part of
  some values from: right posterior bronchus
has db xref: FMA:14049
has db xref: LMMA:00124
id: LMHA:00124
has domain: anatomy

tracheal cartilaginous ring
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal submucosa
has db xref: LMMA:00606
id: LMHA:00133
has domain: anatomy
synonym: cartilage

connective tissue cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial adventitia
subclass of: Restriction
  on property: part of
  some values from: bronchiolar adventitia
subclass of: Restriction
  on property: part of
  some values from: tracheal adventitia
subclass of: Restriction
  on property: part of
  some values from: visceral connective tissue
subclass of: Restriction
  on property: part of
  some values from: tracheal submucosa
subclass of: Restriction
  on property: part of
  some values from: bronchial submucosa
subclass of: Restriction
  on property: part of
  some values from: vascular connective tissue
subclass of: Restriction
  on property: part of
  some values from: tracheal lamina propria
subclass of: Restriction
  on property: part of
  some values from: left lower lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: left upper lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: right lower lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: right middle lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: right upper lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: bronchiolar lamina propria
subclass of: Restriction
  on property: part of
  some values from: bronchial lamina propria
has db xref: CL:0002320
has db xref: LMMA:00136
id: LMHA:00136
definition: A group of cells derived from embryonic mesoderm (mesenchyme) that includes fibroblasts, cartilage cells, adipocytes, smooth muscle cells and bone cells.
has domain: cell

respiratory bronchiolar lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiole
id: LMHA:00138
has domain: anatomy

respiratory bronchiolar wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiole
id: LMHA:00139
has domain: anatomy

respiratory bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right middle lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right upper lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left upper lobe bronchiole
has db xref: FMA:7412
id: LMHA:00140
display: true
display order: 3
has domain: anatomy

chondrocyte
type: Class
subclass of: Restriction
  on property: part of
  some values from: hyaline cartilage
has db xref: BTO:0000249
has db xref: LMMA:00141
id: LMHA:00141
definition: A type of connective tissue cell that secretes and maintains the structural components of cartilage, primarily collagen and proteoglycans.
display: true
has domain: cell

ciliated cell
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: respiratory bronchiolar epithelial cell
subclass of: membranous bronchiolar epithelial cell
subclass of: submucosal gland duct epithelial cell
has db xref: CL:0000064
has db xref: LMMA:00142
id: LMHA:00142
definition: A columnar epithelial cell with microscopic hair-like processes, i.e., motile cilia, that extend from the apical cell surface. These cells are found in the epithelia of the conducting airways (trachea, bronchi, and bronchioles), where they sweep mucous, dirt, dust, bacteria and other pathogens up and out of the lung, bronchi, and trachea.
display: true
has domain: cell

club cell
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: respiratory bronchiolar epithelial cell
subclass of: membranous bronchiolar epithelial cell
has db xref: CL:0000158
has db xref: LMMA:00143
id: LMHA:00143
definition: The club cell is a non-ciliated, dome-shaped, secretory cell with short microvilli and abundant secretory granules. Its secretory proteins function to protect the bronchiolar epithelium from environmental toxins/irritants. The club cell also has the capacity for self-renewal (maintenance of a progenitor cell pool) and regeneration of the bronchiolar epithelium after injury.
display: true
has domain: cell
synonym: Clara cell
synonym: bronchiolar exocrine cell
synonym: nonciliated secretory cell

collagen fiber
type: Class
subclass of: Restriction
  on property: part of
  some values from: extracellular matrix
has db xref: FMA:63173
has db xref: LMMA:00145
id: LMHA:00145
has domain: tissue
synonym: collagen tissue

collecting duct cell
type: Class
subclass of: submucosal gland duct epithelial cell
has db xref: LMMA:00146
id: LMHA:00146
definition: An epithelial cell located in the ducts (tube-like structures) that transport seromucous secretions from the submucosal glands to the lumen of the upper trachea in the mouse and to the lumen of the cartilaginous airways in the human.
has domain: cell

dendritic cell
type: Class
subclass of: immune cell
subclass of: Restriction
  on property: part of
  some values from: paracortex
subclass of: Restriction
  on property: part of
  some values from: germinal center
has db xref: CL:0000738
has db xref: LMMA:00150
id: LMHA:00150
has domain: cell

elastic fiber
type: Class
subclass of: Restriction
  on property: part of
  some values from: extracellular matrix
has db xref: LMMA:00158
has db xref: UBERON:0002521
id: LMHA:00158
has domain: tissue

eosinophil
type: Class
subclass of: granulocyte
has db xref: CL:0000771
has db xref: LMMA:00163
id: LMHA:00163
has domain: cell

external elastic membrane
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica media
has db xref: LMMA:00167
has db xref: UBERON:0015433
id: LMHA:00167
has domain: anatomy

extracellular matrix
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar interstitial tissue
subclass of: Restriction
  on property: part of
  some values from: bronchial adventitia
subclass of: Restriction
  on property: part of
  some values from: bronchiolar adventitia
subclass of: Restriction
  on property: part of
  some values from: hyaline cartilage
subclass of: Restriction
  on property: part of
  some values from: tracheal adventitia
subclass of: Restriction
  on property: part of
  some values from: visceral connective tissue
subclass of: Restriction
  on property: part of
  some values from: tracheal submucosa
subclass of: Restriction
  on property: part of
  some values from: bronchial submucosa
subclass of: Restriction
  on property: part of
  some values from: vascular connective tissue
subclass of: Restriction
  on property: part of
  some values from: tracheal lamina propria
subclass of: Restriction
  on property: part of
  some values from: left lower lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: left upper lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: right lower lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: right upper lobe interlobular septum
subclass of: Restriction
  on property: part of
  some values from: bronchiolar lamina propria
subclass of: Restriction
  on property: part of
  some values from: bronchial lamina propria
has db xref: LMMA:00168
has db xref: MESH:D005109
id: LMHA:00168
has domain: tissue

glycoprotein
type: Class
subclass of: Restriction
  on property: part of
  some values from: ground substance
has db xref: FMA:62925
has db xref: LMMA:00178
id: LMHA:00178
has domain: anatomy

granulocyte
type: Class
subclass of: myeloid leukocyte
subclass of: blood cell
has db xref: CL:0000094
has db xref: LMMA:00179
id: LMHA:00179
has domain: cell

ground substance
type: Class
subclass of: Restriction
  on property: part of
  some values from: extracellular matrix
has db xref: LMMA:00180
id: LMHA:00180
has domain: anatomy

macrophage
type: Class
subclass of: myeloid leukocyte
has db xref: CL:0000235
has db xref: LMMA:00182
id: LMHA:00182
HTC code: MCL
has domain: cell
synonym: histiocyte

hyaline cartilage
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal cartilaginous ring
subclass of: Restriction
  on property: part of
  some values from: bronchial cartilaginous ring
has db xref: FMA:64783
has db xref: LMMA:00183
id: LMHA:00183
display: true
has domain: anatomy

immune cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory immune system
has db xref: CL:0000738
has db xref: LMMA:00185
id: LMHA:00185
HTC code: MIC
has abbreviation: MIC
has domain: cell
synonym: leukocyte
synonym: white blood cell

internal elastic membrane
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica intima
has db xref: LMMA:00191
has db xref: UBERON:0011392
id: LMHA:00191
has domain: anatomy

left lung
type: Class
subclass of: lung
has db xref: LMMA:00199
has db xref: UBERON:0002168
id: LMHA:00199
has domain: anatomy

left lower lobe alveolar parenchyma
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobe
id: LMHA:00200
display order: 3
has domain: anatomy
synonym: respiratory parenchyma
analogous to: LMMA:00200

left lower lobe bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobe
has db xref: UBERON:0012055
id: LMHA:00201
display order: 2
has domain: anatomy

left lower lobe hilum
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobe
id: LMHA:00202
display order: 1
has domain: anatomy

left lung main bronchus
type: Class
subclass of: main bronchus
has db xref: LMMA:00205
has db xref: UBERON:0002178
id: LMHA:00205
HTC code: BRL
has domain: anatomy
synonym: bronchus left

left lower lobe visceral pleura
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobe
id: LMHA:00207
display order: 4
has domain: anatomy
analogous to: LMMA:00207

lipofibroblast
type: Class
subclass of: alveolar interstitial cell
has db xref: LMMA:00209
id: LMHA:00209
definition: Lipid-containing interstitial cell located in the alveolar septum (wall). The lipofibroblast transfers neutral lipid (tryglyceride) from the capillaries to the type II pneumocyte for the synthesis of surfactant phopholipids. It also synthesizes ECM proteins, such as collagen and elastin, and contains intermediate contractile filaments.
display: true
has domain: cell

lung
type: Class
has db xref: EHDAA2:0001042
has db xref: EMAPA:16728
has db xref: FMA:7195
has db xref: LMMA:00211
has db xref: MA:0000415
has db xref: UBERON:0002048
id: LMHA:00211
display order: 3
has domain: anatomy

interstitial macrophage
type: Class
subclass of: macrophage
id: LMHA:00213
has domain: cell
synonym: lung tissue macrophage
synonym: pulmonary interstitial macrophage

pulmonary surfactant
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar duct lumen
subclass of: Restriction
  on property: part of
  some values from: alveolar lumen
subclass of: Restriction
  on property: located_in
  some values from: alveolar duct lumen
subclass of: Restriction
  on property: located_in
  some values from: alveolar lumen
subclass of: Restriction
  on property: located_in
  some values from: alveolar sac lumen
has db xref: LMMA:00215
has db xref: UBERON:0008826
id: LMHA:00215
has domain: anatomy
located in: alveolar duct lumen
synonym: lung surfactant

lymphatic endothelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphatic endothelium
has db xref: CL:0002138
has db xref: LMMA:00216
id: LMHA:00216
HTC code: END
HTC code: LYM
definition: A mesenchymal-derived, squamous (flat), endothelial cell that lines the inner (i.e., luminal) surface of lymphatic vessels, forming a continuous, thin, endothelial cell layer or sheath (endothelium).
display: true
has domain: cell

lymphatic smooth muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphatic vessel tunica media
has db xref: LMMA:00217
has db xref: UBERON:0004232
id: LMHA:00217
has domain: anatomy

lymphatic vessel tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary lymphatic vessel
has db xref: FMA:66259
has db xref: LMMA:00220
id: LMHA:00220
has domain: anatomy

lymphatic vessel tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary lymphatic vessel
has db xref: FMA:66257
has db xref: LMMA:00221
id: LMHA:00221
has domain: anatomy

lymphatic vessel tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary lymphatic vessel
has db xref: FMA:66258
has db xref: LMMA:00222
id: LMHA:00222
has domain: anatomy

lymphocyte
type: Class
subclass of: lymphoid cell
has db xref: CL:0000542
has db xref: LMMA:00223
id: LMHA:00223
has domain: cell

lymph node
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphoid tissue
has db xref: LMMA:00224
has db xref: UBERON:0000029
id: LMHA:00224
has domain: anatomy

alveolar macrophage
type: Class
subclass of: macrophage
subclass of: Restriction
  on property: part of
  some values from: alveolar duct lumen
subclass of: Restriction
  on property: part of
  some values from: alveolar lumen
subclass of: Restriction
  on property: located_in
  some values from: LMMA_00063
subclass of: Restriction
  on property: located_in
  some values from: LMMA_00068
subclass of: Restriction
  on property: located_in
  some values from: LMMA_00818
has db xref: CL:0000583
has db xref: LMMA:00226
id: LMHA:00226
HTC code: MCL
display: true
has domain: cell
located in: alveolar duct lumen
synonym: tissue macrophage

mast cell
type: Class
subclass of: myeloid leukocyte
has db xref: CL:0000097
has db xref: LMMA:00227
id: LMHA:00227
has domain: cell

mesothelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: visceral mesothelium
has db xref: CL:0000077
has db xref: LMMA:00231
id: LMHA:00231
definition: A flat cell of mesenchymal origin that forms the superficial layer of the serosal membranes lining the body cavities of the abdomen and thorax.
display: true
has domain: cell

monocyte
type: Class
subclass of: myeloid leukocyte
subclass of: blood cell
has db xref: CL:0000576
has db xref: LMMA:00233
id: LMHA:00233
has domain: cell

mucus cell
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: membranous bronchiolar epithelial cell
subclass of: submucosal gland epithelial cell
has db xref: LMMA:00238
has db xref: MESH:D009077
id: LMHA:00238
definition: An epithelial cell that produces and secretes mucin, a substance containing mucopolysaacharides and protein, whch protects the epithelial cell surface. Mucous cells are found predominantely in the submucosal glands of the trachea and more rarely in the epithelum of the cartilaginous airways.
display: true
has domain: cell
synonym: mucous cell

bronchiolar smooth muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar wall
has db xref: LMMA:00240
has db xref: UBERON:0004515
id: LMHA:00240
has domain: tissue
synonym: peribronchiolar smooth muscle

myeloid leukocyte
type: Class
subclass of: immune cell
has db xref: CL:0000766
has db xref: LMMA:00241
id: LMHA:00241
definition: A cell of the monocyte, granulocyte, or mast cell lineage.
has domain: cell

myoepithelial cell
type: Class
subclass of: submucosal gland epithelial cell
has db xref: BTO:0002309
has db xref: LMMA:00242
id: LMHA:00242
definition: A contractile cell found between secretory cells and basement membrane of the seromucus glands located in the submucosa of the upper trachea in the mouse and human. Each myoepithelial cell has long cytoplasmic processes that wrap around a secretory unit (acinus, or smalll cluster of cells with a central lumen). The contraction of the myoepithelial processes forces the secretory product from the secretory unit into its duct.
has domain: cell

myofibroblast
type: Class
subclass of: alveolar interstitial cell
has db xref: BTO:0001946
has db xref: LMMA:00243
id: LMHA:00243
definition: A stromal cell combining the features of a fibroblast and a smooth muscle cell, such as alpha-smooth-muscle-actin positive, contractile myofilaments
display: true
has domain: cell

natural killer cell
type: Class
subclass of: innate lymphoid cell
has db xref: CL:0000623
has db xref: LMMA:00245
id: LMHA:00245
HTC code: NKC
has domain: cell
synonym: large granular lymphocyte
synonym: non-T, non-B lymphocyte

nerve fiber
type: Class
subclass of: Restriction
  on property: part of
  some values from: non-adrenergic and non-cholinergic nerve
subclass of: Restriction
  on property: part of
  some values from: postganglionic parasympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: postganglionic sympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: preganglionic parasympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: general visceral afferent nerve
has db xref: LMMA:00247
has db xref: UBERON:0006134
id: LMHA:00247
HTC code: NRV
has domain: anatomy

neuroendocrine cell
type: Class
subclass of: neuroepithelial body
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: respiratory bronchiolar epithelial cell
subclass of: membranous bronchiolar epithelial cell
has db xref: CL:0000165
has db xref: LMMA:00252
id: LMHA:00252
definition: An endocrine cell that produces and secretes neurotransmitters and neuropeptide hormones in response to neuronal signals. In the lung, these cells are found as single cells or in cell clusters (neuroepithelial bodies) and are located in the epithelium of the conducting airways, including trachea, bronchi, and bronchioles.
display: true
has domain: cell

neuroepithelial body
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: respiratory bronchiolar epithelial cell
subclass of: membranous bronchiolar epithelial cell
has db xref: MESH:D046568
id: LMHA:00253
display: true
has domain: cell
comment: Innervated clusters of NEUROEPITHELIAL CELLS found in the LUNGS. They act as airway OXYGEN sensors, releasing regulatory PEPTIDES and SEROTONIN in response to HYPOXIA.

neutrophil
type: Class
subclass of: granulocyte
has db xref: CL:0000775
has db xref: LMMA:00256
id: LMHA:00256
has domain: cell

non-adrenergic and non-cholinergic nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic nerve
has db xref: LMMA:00257
id: LMHA:00257
HTC code: NRV
has domain: anatomy
synonym: sensory nervous system

postganglionic parasympathetic nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic nerve
has db xref: LMMA:00270
has db xref: UBERON:0011929
id: LMHA:00270
HTC code: NRV
has domain: anatomy
synonym: cholinergic innervation

pericyte
type: Class
subclass of: alveolar interstitial cell
subclass of: subendothelial connective tissue cell
subclass of: Restriction
  on property: part of
  some values from: alveolar capillary endothelium
subclass of: Restriction
  on property: adjacent_to
  some values from: alveolar capillary endothelium
subclass of: Restriction
  on property: adjacent_to
  some values from: alveolar interstitial cell
has db xref: CL:0000669
has db xref: LMMA:00273
id: LMHA:00273
definition: Unique slender cells with multiple processes extending along the capillary vessel and encircling the vascular wall to form a net around the vessel. These cells are embedded in the basement membrane shared with the endothelial cells of the vessel. They are are important in maintaining vessel integrity, angiogenesis, and vascular remodeling.
display: true
has domain: cell

primary alveolar septum
type: Class
subclass of: interalveolar septum
has db xref: LMMA:00279
has db xref: UBERON:0005314
id: LMHA:00279
display: true
display order: 1
has domain: anatomy
synonym: primary septum
comment: primary alveolar septum gives rise to the alveolar septal crest, which develops into secondary alveolar septum

proteoglycan
type: Class
subclass of: Restriction
  on property: part of
  some values from: ground substance
has db xref: FMA:63015
has db xref: LMMA:00283
id: LMHA:00283
has domain: anatomy

respiratory bronchiolar epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar wall
id: LMHA:00286
display: true
has domain: tissue
synonym: central bronchiolar epithelium

tracheal epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal mucosa
has db xref: LMMA:00414
has db xref: UBERON:0001901
id: LMHA:00288
has domain: tissue

pulmonary arteriole
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary blood vessel
has db xref: LMMA:00290
id: LMHA:00290
display: true
display order: 2
has domain: anatomy

pulmonary artery
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary blood vessel
has db xref: LMMA:00291
has db xref: UBERON:0002012
id: LMHA:00291
display: true
display order: 1
has domain: anatomy

pulmonary artery tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery
has db xref: FMA:84914
has db xref: LMMA:00292
id: LMHA:00292
has domain: anatomy

pulmonary artery tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery
has db xref: LMMA:00293
id: LMHA:00293
has domain: anatomy

pulmonary artery tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery
has db xref: LMMA:00294
id: LMHA:00294
has domain: anatomy

pulmonary distal arteriole
type: Class
subclass of: pulmonary arteriole
has db xref: LMMA:00297
id: LMHA:00297
has domain: anatomy
synonym: pulmonary terminal arteriole

pulmonary distal arteriole tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole
has db xref: LMMA:00298
id: LMHA:00298
has domain: anatomy

pulmonary distal arteriole tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole
has db xref: LMMA:00299
id: LMHA:00299
has domain: anatomy

pulmonary distal arteriole tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole
has db xref: LMMA:00300
id: LMHA:00300
has domain: anatomy

pulmonary distal venule
type: Class
subclass of: pulmonary venule
has db xref: LMMA:00301
id: LMHA:00301
has domain: anatomy

pulmonary distal venule tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule
has db xref: LMMA:00302
id: LMHA:00302
has domain: anatomy

pulmonary distal venule tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule
has db xref: LMMA:00303
id: LMHA:00303
has domain: anatomy

pulmonary muscular arteriole
type: Class
subclass of: pulmonary arteriole
has db xref: LMMA:00304
id: LMHA:00304
has domain: anatomy

pulmonary vein
type: Class
subclass of: pulmonary blood vessel
has db xref: LMMA:00305
has db xref: UBERON:0002016
id: LMHA:00305
display order: 4
has domain: anatomy

pulmonary vein tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein
has db xref: FMA:84915
has db xref: LMMA:00306
id: LMHA:00306
has domain: anatomy

pulmonary vein tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein
has db xref: FMA:84945
has db xref: LMMA:00307
id: LMHA:00307
has domain: anatomy

pulmonary vein tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein
has db xref: FMA:85023
has db xref: LMMA:00308
id: LMHA:00308
has domain: anatomy

pulmonary muscular venule
type: Class
subclass of: pulmonary venule
has db xref: LMMA:00309
id: LMHA:00309
has domain: anatomy

pulmonary muscular venule tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule
has db xref: LMMA:00310
id: LMHA:00310
has domain: anatomy

pulmonary muscular venule tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule
has db xref: LMMA:00311
id: LMHA:00311
has domain: anatomy

pulmonary muscular venule tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule
has db xref: LMMA:00312
id: LMHA:00312
has domain: anatomy

pulmonary blood vessel
type: Class
subclass of: respiratory vascular system
has db xref: LMMA:00315
id: LMHA:00315
has domain: anatomy

pulmonary venule
type: Class
subclass of: pulmonary blood vessel
has db xref: LMMA:00316
id: LMHA:00316
display: true
display order: 5
has domain: anatomy

reticular fiber
type: Class
subclass of: Restriction
  on property: part of
  some values from: extracellular matrix
has db xref: LMMA:00320
has db xref: UBERON:0006804
id: LMHA:00320
has domain: anatomy

right lung lower lobe
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung
has db xref: EHDAA2:0001740
has db xref: LMMA:00324
id: LMHA:00324
HTC code: CBL
HTC code: RLL
display order: 3
has domain: anatomy
synonym: right inferior lobe

right lung lower lobar bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lobar bronchus
has db xref: EHDAA2:0001744
has db xref: LMMA:00325
id: LMHA:00325
display order: 3
has domain: anatomy
synonym: secondary bronchus

right lung
type: Class
subclass of: lung
has db xref: LMMA:00326
has db xref: UBERON:0002167
id: LMHA:00326
has domain: anatomy

right lung main bronchus
type: Class
subclass of: main bronchus
has db xref: LMMA:00329
has db xref: UBERON:0002177
id: LMHA:00329
HTC code: BRR
has domain: anatomy
synonym: bronchus right

right lung middle lobe
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung
has db xref: LMMA:00330
has db xref: UBERON:0002174
id: LMHA:00330
HTC code: CBL
HTC code: RML
display order: 2
has domain: anatomy
synonym: right middle lobe

right lung middle lobar bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lobar bronchus
has db xref: LMMA:00331
has db xref: UBERON:0012063
id: LMHA:00331
display order: 2
has domain: anatomy
synonym: secondary bronchus

right lung upper lobe
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung
has db xref: EHDAA2:0001747
has db xref: LMMA:00332
id: LMHA:00332
HTC code: CBL
HTC code: RUL
display order: 1
has domain: anatomy
synonym: right superior lobe

right lung upper lobar bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lobar bronchus
has db xref: EHDAA2:0001752
has db xref: LMMA:00333
id: LMHA:00333
display order: 1
has domain: anatomy
synonym: secondary bronchus

glial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: non-adrenergic and non-cholinergic nerve
subclass of: Restriction
  on property: part of
  some values from: postganglionic parasympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: postganglionic sympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic ganglion
subclass of: Restriction
  on property: part of
  some values from: preganglionic parasympathetic nerve
subclass of: Restriction
  on property: part of
  some values from: general visceral afferent nerve
has db xref: CL:0000218
has db xref: LMMA:00338
id: LMHA:00338
definition: A supporting cell of the peripheral nervous system, derived from neural crest cells, which forms the insulating myelin sheaths of peripheral axons and is required for nerve maintenance and function.
has domain: cell
synonym: Schwann cell
synonym: neuroglial cell

secondary alveolar septum
type: Class
subclass of: interalveolar septum
has db xref: LMMA:00339
has db xref: UBERON:0005315
id: LMHA:00339
display: true
display order: 3
has domain: anatomy
comment: primary alveolar septum gives rise to the alveolar septal crest, which develops into secondary alveolar septum

serous cell
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: membranous bronchiolar epithelial cell
subclass of: submucosal gland epithelial cell
has db xref: CL:0000313
has db xref: LMMA:00340
id: LMHA:00340
definition: An epithelial cell that produces and secretes water, electrolytes, antimicrobial, anti-inflammatory, and antioxidant molecules, which protects the epithelial surrface. Serous cells are found predominantely in the submucosal glands of the trachea and more rarely in the epithelum of the cartilaginous airways.
has domain: cell

smooth muscle cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial smooth muscle
subclass of: Restriction
  on property: part of
  some values from: lymphatic smooth muscle
subclass of: Restriction
  on property: part of
  some values from: bronchiolar smooth muscle
subclass of: Restriction
  on property: part of
  some values from: tracheal smooth muscle
subclass of: Restriction
  on property: part of
  some values from: trachealis muscle
subclass of: Restriction
  on property: part of
  some values from: vascular smooth muscle
has db xref: CL:0000192
has db xref: LMMA:00343
id: LMHA:00343
definition: A non-striated, elongated, spindle-shaped, involuntary contractile cell found in internal organs and blood vessels. Smooth muscle cells are found in the walls of the conducting airways (trachea, bronchi, bronchioles) and of the pulmonary and bronchial blood vessels (vascular smooth muscle).
display: true
has domain: cell

submucosal gland epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: submucosal gland
has db xref: LMMA:00351
id: LMHA:00351
has domain: anatomy

postganglionic sympathetic nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic nerve
has db xref: LMMA:00352
has db xref: UBERON:0011926
id: LMHA:00352
HTC code: NRV
has domain: anatomy
synonym: adrenergic innervation

T lymphocyte
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: part of
  some values from: paracortex
subclass of: Restriction
  on property: part of
  some values from: mantle zone
subclass of: Restriction
  on property: part of
  some values from: germinal center
subclass of: Restriction
  on property: part of
  some values from: marginal zone
subclass of: Restriction
  on property: part of
  some values from: bronchus-associated lymphoid tissue
has db xref: CL:0000084
has db xref: LMMA:00354
id: LMHA:00354
has domain: cell
synonym: T cell

telocyte
type: Class
subclass of: alveolar interstitial cell
subclass of: connective tissue cell
subclass of: subendothelial connective tissue cell
has db xref: LMMA:00356
has db xref: MESH:D000067170
id: LMHA:00356
definition: The telocyte is a type of fibroblast (interstitial/connective tissue cell) that has a small oval-shaped cell body with multiple (1-5), thin, elongated telopods (cytoplasmic extensions) that can be up to 100-microns long. These cells are C-KIT positive and are associated with morphogenesis and local tissue homeostasis.
has domain: cell

terminal bronchiolar lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiole
has db xref: FMA:87486
has db xref: LMMA:00357
id: LMHA:00357
has domain: anatomy

terminal bronchiolar wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiole
has db xref: FMA:62792
has db xref: LMMA:00358
id: LMHA:00358
has domain: anatomy

terminal bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right middle lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right upper lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left upper lobe bronchiole
has db xref: LMMA:00359
has db xref: UBERON:0002187
id: LMHA:00359
display: true
display order: 2
has domain: anatomy
synonym: membranous bronchiole

trachea
type: Class
has db xref: EHDAA2:0002066
has db xref: EMAPA:16853
has db xref: FMA:7394
has db xref: LMMA:00361
has db xref: MA:0000441
has db xref: UBERON:0003126
id: LMHA:00361
display: true
display order: 1
has domain: anatomy

trachea bifurcation
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea
has db xref: LMMA:00362
has db xref: UBERON:0015247
id: LMHA:00362
display order: 3
has domain: anatomy

trachea lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea
has db xref: LMMA:00365
has db xref: UBERON:0006833
id: LMHA:00364
display order: 1
has domain: anatomy

trachea wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea
has db xref: FMA:7470
has db xref: LMMA:00366
id: LMHA:00366
display order: 2
has domain: anatomy

tracheal adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea wall
has db xref: LMMA:00367
id: LMHA:00367
display order: 3
has domain: anatomy

tracheal smooth muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal mucosa
id: LMHA:00369
has domain: anatomy

trachealis muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal cartilaginous ring
has db xref: LMMA:00370
id: LMHA:00370
has domain: anatomy
synonym: membranous trachea

subendothelial connective tissue cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica intima
has db xref: LMMA:00378
id: LMHA:00378
definition: A fibroblast found in the connective tissue layer located immediately under the vascular endothelium in the tunica intima of blood vessels.
has domain: cell

type I pneumocyte
type: Class
subclass of: alveolar epithelial cell
has db xref: CL:0002062
has db xref: LMMA:00379
id: LMHA:00379
HTC code: EP1
definition: A thin, flat or squamous ("scale-like") alveolar epithelial cell, covering ~95% of the surface area of each alveolus, that facilitates gas exchange across the alveolar wall (septum), i.e., between the alveolus (airspace) and the capillary network.
display: true
has domain: cell
synonym: AEC1
synonym: AT1 cell
synonym: ATI cell
synonym: alveolar type 1 cell
synonym: alveolar type I cell
synonym: alveolar type I epithelial cell
synonym: lung type 1 cell
synonym: pulmonary alveolar type I cell
synonym: squamous alveolar cell
synonym: squamous alveolar lining cell
synonym: type I alveolar cell
synonym: type I alveolar epithelial cell

type II pneumocyte
type: Class
subclass of: alveolar epithelial cell
has db xref: CL:0002063
has db xref: LMMA:00381
id: LMHA:00381
HTC code: EP2
definition: A cuboidal-like, alveolar epithelial cell that synthesizes, stores, secretes, and recycles pulmonary surfactant phospholipids and proteins, substances that reduce the surface tension in the alveolus. Pulmonary surfactant is stored in lipid-rich lamellar bodies, a distinctive feature of this cell type.. The type II pneumocyte is also capable of cell division and can repopulate the alveolar epitheium after injury, differentiating into type I pneumocytes. Although this cell type covers less than 5% of the alveolar surface, it represents 60% of all alveolar epithelial cells.
display: true
has domain: cell
synonym: AT2 cell
synonym: ATII cell
synonym: TII (type II)
synonym: alveolar epithelial type II cell
synonym: alveolar type II cell
synonym: cuboidal type II cell
synonym: granular pneumocyte
synonym: lung type 2 cell
synonym: type 2 alveolar epithelial cell
synonym: type 2 pneumocyte
synonym: type II alveolar cell
synonym: type II alveolar epithelial cell

unclassified epithelial cell
type: Class
subclass of: bronchial epithelial cell
subclass of: terminal bronchiolar epithelial cell
subclass of: tracheal epithelial cell
subclass of: alveolar epithelial cell
subclass of: respiratory bronchiolar epithelial cell
subclass of: membranous bronchiolar epithelial cell
has db xref: LMMA:00384
id: LMHA:00384
display: true
has domain: cell
synonym: general epithelial cell
synonym: nonspecific epithelial cell

unclassified fibroblast
type: Class
subclass of: alveolar interstitial cell
subclass of: connective tissue cell
has db xref: LMMA:00386
id: LMHA:00386
definition: This term is used to describe a fibroblast that cannot be classified under an existing fibroblast cell type.
has domain: cell

vascular endothelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar capillary endothelium
has db xref: CL:0002139
has db xref: LMMA:00392
id: LMHA:00392
HTC code: END
definition: An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
display: true
has domain: cell

vascular smooth muscle
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica media
has db xref: LMMA:00393
has db xref: UBERON:0004237
id: LMHA:00393
display: true
has domain: anatomy

vasa vasorum
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica adventitia
has db xref: LMMA:00395
has db xref: UBERON:0003710
id: LMHA:00395
has domain: anatomy

vein endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica intima
has db xref: LMMA:00397
has db xref: UBERON:0001919
id: LMHA:00397
has domain: tissue

venule endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica intima
has db xref: LMMA:00403
has db xref: UBERON:0007141
id: LMHA:00403
has domain: tissue

visceral connective tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: right middle lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: right upper lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: left lower lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: left upper lobe visceral pleura
has db xref: LMMA:00405
id: LMHA:00405
has domain: tissue

visceral mesothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: right middle lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: right upper lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: left lower lobe visceral pleura
subclass of: Restriction
  on property: part of
  some values from: left upper lobe visceral pleura
has db xref: LMMA:00406
has db xref: UBERON:0007141
id: LMHA:00406
has domain: tissue

fibroelastic membrane
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal cartilaginous ring
subclass of: Restriction
  on property: part of
  some values from: bronchial cartilaginous ring
has db xref: LMMA:00410
id: LMHA:00410
has domain: tissue
synonym: fibroelastic connective tissue
synonym: fibroelastic tissue

perichondrium
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal cartilaginous ring
subclass of: Restriction
  on property: part of
  some values from: bronchial cartilaginous ring
has db xref: LMMA:00412
has db xref: UBERON:0002222
id: LMHA:00412
has domain: tissue

tracheal mucosa
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea wall
has db xref: LMMA:00415
has db xref: UBERON:0000379
id: LMHA:00415
display order: 1
has domain: tissue

tracheal submucosa
type: Class
subclass of: Restriction
  on property: part of
  some values from: trachea wall
has db xref: LMMA:00416
has db xref: UBERON:0002202
id: LMHA:00416
display order: 2
has domain: tissue

bronchial mucosa
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchus wall
has db xref: LMMA:00418
has db xref: UBERON:0000410
id: LMHA:00418
display order: 1
has domain: tissue

bronchial submucosa
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchus wall
has db xref: LMMA:00419
has db xref: UBERON:0001957
id: LMHA:00419
display order: 2
has domain: tissue

lymphatic endothelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphatic vessel tunica intima
has db xref: LMMA:00422
has db xref: UBERON:0002042
id: LMHA:00422
display: true
has domain: tissue

nuocyte
type: Class
subclass of: innate lymphoid cell
has db xref: CL:0002089
has db xref: LMMA:00437
id: LMHA:00437
has domain: cell

vascular connective tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial vein tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: bronchial venule tunica media
subclass of: Restriction
  on property: part of
  some values from: lymphatic vessel tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: lymphatic vessel tunica intima
subclass of: Restriction
  on property: part of
  some values from: lymphatic vessel tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary artery tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal arteriole tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary distal venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary vein tunica media
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular venule tunica media
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: bronchial artery tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica adventitia
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica intima
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole tunica media
has db xref: LMMA:00440
id: LMHA:00440
has domain: tissue
synonym: perivascular connective tissue

pulmonary lymphatic vessel
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory vascular system
has db xref: LMMA:00447
has db xref: UBERON:0018227
id: LMHA:00447
display order: 6
has domain: anatomy

submucosal gland duct epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: submucosal gland
has db xref: BTO:0004557
has db xref: LMMA:00455
id: LMHA:00455
has domain: tissue

terminal bronchiolar epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar wall
has db xref: FMA:62794
has db xref: LMMA:00457
id: LMHA:00457
has domain: tissue

bronchial arteriole tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial arteriole
has db xref: LMMA:00472
id: LMHA:00472
has domain: anatomy

bronchial artery tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial artery
has db xref: LMMA:00473
id: LMHA:00473
has domain: anatomy

tracheal lamina propria
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal mucosa
has db xref: LMMA:00483
has db xref: UBERON:0000031
id: LMHA:00483
has domain: anatomy

pulmonary muscular arteriole tunica adventitia
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole
has db xref: LMMA:00486
id: LMHA:00486
has domain: anatomy

pulmonary muscular arteriole tunica intima
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole
has db xref: LMMA:00488
id: LMHA:00488
has domain: anatomy

pulmonary muscular arteriole tunica media
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary muscular arteriole
has db xref: LMMA:00489
id: LMHA:00489
has domain: anatomy

left anterior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
has db xref: FMA:7428
id: LMHA:00516
display order: 3
has domain: anatomy
located in: LUL
synonym: tertiary bronchus

left anterior basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
id: LMHA:00517
display order: 7
has domain: anatomy
located in: LLL
synonym: tertiary bronchus

left apical bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
has db xref: FMA:7426
id: LMHA:00518
display order: 1
has domain: anatomy
located in: LLL
synonym: tertiary bronchus

autonomic neuron
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic ganglion
has db xref: CL:0000107
has db xref: LMMA:00521
id: LMHA:00521
definition: A neuron whose cell body is located within an autonomic ganglion, i.e., part of a cluster of nerve cell bodies in the peripheral nervous system. Each neuron consists of a body, an axon, and dendrites. Its purpose is to receive, conduct, and transmit impulses between the central nervous system and its target organs/tissues.
has domain: cell
synonym: autonomic ganglion cell
synonym: autonomic ganglion neuron
synonym: neuron
synonym: neuronal cell

inferior lingular bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
has db xref: FMA:7431
id: LMHA:00523
display order: 5
has domain: anatomy
located in: LUL
synonym: tertiary bronchus

intermediate airway progenitor cell
type: Class
subclass of: bronchial epithelial cell
subclass of: tracheal epithelial cell
has db xref: LMMA:00526
id: LMHA:00524
has domain: cell

left lateral basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
has db xref: FMA:7507
id: LMHA:00525
display order: 8
has domain: anatomy
located in: LLL
synonym: tertiary bronchus

right lateral bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
id: LMHA:00526
definition: An epithelial cell found in the extrapulmonary conducting airways (tracheal and bronchial epithelia). This cell is a non-proliferative, TRP63-negative, MYB-positive, progenitor cell that can give rise to both ciliated and secretory cell types. It is distinct from basal cells, which are TRP63-positive, MYB-negative, and self-renewing.
display order: 4
has domain: anatomy
located in: RML
synonym: tertiary bronchus

left lung lobar bronchus
type: Class
subclass of: lobar bronchus
has db xref: UBERON:0003405
id: LMHA:00527
has domain: anatomy

left lung lower lobar bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lobar bronchus
has db xref: UBERON:0012066
id: LMHA:00528
display order: 2
has domain: anatomy

left lung lower lobe
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung
id: LMHA:00529
HTC code: CBL
HTC code: LLL
has domain: anatomy
synonym: left inferior lobe

left lung segmental bronchus
type: Class
subclass of: segmental bronchus
id: LMHA:00530
has domain: anatomy

left lung upper lobar bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lobar bronchus
has db xref: UBERON:0012065
id: LMHA:00531
display order: 1
has domain: anatomy

left lung upper lobe
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung
has db xref: UBERON:0008952
id: LMHA:00532
HTC code: CBL
HTC code: LUL
has domain: anatomy
synonym: left superior lobe

left upper lobe alveolar parenchyma
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobe
id: LMHA:00533
display order: 3
has domain: anatomy
analogous to: LMMA:00200

left upper lobe bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobe
has db xref: UBERON:0012056
id: LMHA:00534
display order: 2
has domain: anatomy

left upper lobe hilum
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobe
id: LMHA:00535
display order: 1
has domain: anatomy

left upper lobe visceral pleura
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobe
id: LMHA:00537
display order: 4
has domain: anatomy
analogous to: LMMA:00207

lobar bronchus
type: Class
subclass of: bronchus
has db xref: LMMA:00528
has db xref: UBERON:0002183
id: LMHA:00538
display order: 2
has domain: anatomy
synonym: secondary bronchus

right anterior basal segmental bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:7418
id: LMHA:00539
display order: 8
has domain: anatomy
located in: RLL
synonym: tertiary bronchus

main bronchus
type: Class
subclass of: bronchus
has db xref: LMMA:00527
has db xref: UBERON:0002182
id: LMHA:00540
display order: 1
has domain: anatomy
synonym: mainstem bronchus
synonym: primary bronchus

medial basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:13275
id: LMHA:00541
display order: 7
has domain: anatomy
located in: RLL
synonym: tertiary bronchus

medial bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:7403
id: LMHA:00542
display order: 5
has domain: anatomy
located in: RML
synonym: tertiary bronchus

left posterior basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
has db xref: FMA:7508
id: LMHA:00544
display order: 9
has domain: anatomy
located in: LLL
synonym: tertiary bronchus

left posterior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
id: LMHA:00545
display order: 2
has domain: anatomy
located in: LUL
synonym: tertiary bronchus

respiratory autonomic nervous system
type: Class
has db xref: LMMA:00520
id: LMHA:00546
display order: 4
has domain: anatomy
synonym: autonomic respiratory nervous system

respiratory immune system
type: Class
has db xref: LMMA:00522
id: LMHA:00547
HTC code: TLD
HTC code: TLP
HTC code: TRD
HTC code: TRP
display order: 5
has domain: anatomy

respiratory vascular system
type: Class
has db xref: LMMA:00523
has db xref: UBERON:0003504
id: LMHA:00548
display order: 6
has domain: anatomy
synonym: respiratory vasculature

right lung lobar bronchus
type: Class
subclass of: lobar bronchus
id: LMHA:00549
HTC code: BRR
has domain: anatomy

right lung segmental bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: segmental bronchus
id: LMHA:00550
HTC code: BRR
has domain: anatomy

segmental bronchus
type: Class
subclass of: bronchus
has db xref: FMA:7407
id: LMHA:00551
display order: 3
has domain: anatomy
synonym: tertiary bronchus

left lower lobe superior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
id: LMHA:00552
display order: 6
has domain: anatomy
located in: LLL
synonym: tertiary bronchus

superior lingular bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung segmental bronchus
id: LMHA:00553
display order: 4
has domain: anatomy
located in: LUL
synonym: tertiary bronchus

right upper lobe anterior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
id: LMHA:00554
display order: 2
has domain: anatomy
located in: RUL
synonym: tertiary bronchus

left lower lobe interlobular septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung lower lobe
id: LMHA:00559
display order: 5
has domain: anatomy

left upper lobe interlobular septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: left lung upper lobe
id: LMHA:00560
display order: 5
has domain: anatomy

respiratory bronchiolar alveolus
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiole
id: LMHA:00563
has domain: anatomy

right lower lobe interlobular septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung lower lobe
id: LMHA:00564
display order: 5
has domain: anatomy

right middle lobe interlobular septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung middle lobe
id: LMHA:00565
display order: 5
has domain: anatomy

right upper lobe interlobular septum
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung upper lobe
id: LMHA:00566
display order: 5
has domain: anatomy

lymphoid follicle
type: Class
subclass of: Restriction
  on property: part of
  some values from: cortex
has db xref: UBERON:0000444
id: LMHA:00567
has domain: cell
synonym: folliculus lymphaticus
synonym: lymphatic follicle
synonym: lymphatic nodule
synonym: lymphoid nodule
synonym: nodular lymphoid tissue
synonym: nodulus lymphaticus
synonym: nodulus lymphoideus
comment: follicular hyperplasia +/- germinal centers in reactive conditions

paracortex
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymph node
id: LMHA:00560
id: NCIT:C38467
has domain: tissue
synonym: Lymph Node Paracortex
synonym: Lymph Node Paracortical Region
synonym: interfollicular area of the lymph node
comment: predominantly T cells

mantle zone
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphoid follicle
id: LMHA:00569
id: NCIT:C33053
has domain: tissue
comment: predominantly B cells

germinal center
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphoid follicle
has db xref: LMMA:00699
has db xref: UBERON:0010754
id: LMHA:00570
definition: A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
has domain: tissue
synonym: central zone of follicle
synonym: reactive center of follicle

marginal zone
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphoid follicle
id: LMHA:00573
id: NCIT:C49767
has domain: tissue
comment: predominantly B cells

plasma cell
type: Class
subclass of: B lymphocyte
subclass of: Restriction
  on property: part of
  some values from: germinal center
has db xref: BTO:0000392
has db xref: CL:0000786
has db xref: FMA:70574
has db xref: LMMA:00677
id: LMHA:00574
HTC code: BCL
definition: A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive.
definition: An epithelial cell that lines the peripheral gas exchange region (epithelial lining of the alveolar duct and alveoli) of the lungs. Includes both alveolar type I and type II pneumocytes.
has domain: cell
synonym: mature B lymphocyte

glycosaminoglycan
type: Class
subclass of: Restriction
  on property: part of
  some values from: ground substance
has db xref: FMA:63011
has db xref: LMMA:00529
id: LMHA:00576
has domain: anatomy

bronchial epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial epithelium
has db xref: CL:0002328
has db xref: LMMA:00591
id: LMHA:00577
has domain: cell

membranous bronchiole
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right middle lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: right upper lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left lower lobe bronchiole
subclass of: Restriction
  on property: part of
  some values from: left upper lobe bronchiole
id: LMHA:00578
display order: 1
has domain: anatomy
analogous to: LMMA:00140
analogous to: LMMA:00198

membranous bronchiolar lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiole
id: LMHA:00579
has domain: anatomy
analogous to: LMMA:00138
analogous to: LMMA:00196

membranous bronchiolar wall
type: Class
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiole
id: LMHA:00580
has domain: anatomy
analogous to: LMMA:00139
analogous to: LMMA:00197

membranous bronchiolar epithelium
type: Class
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar wall
id: LMHA:00581
has domain: tissue
analogous to: LMMA:00286
analogous to: LMMA:00433

terminal bronchiolar epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar epithelium
id: LMHA:00582
definition: An epithelial cell that lines the intrapulmonary conducting airway, or bronchioles. The more proximal bronchioles are lined predominantly by ciliated cells with a greater proportion of club cells in the distal bronchioles.
has domain: cell

tracheal epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal epithelium
has db xref: CL:0000307
has db xref: LMMA:00590
id: LMHA:00583
has domain: cell

alveolar epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar epithelium
has db xref: FMA:62499
has db xref: LMMA:00574
id: LMHA:00586
has domain: cell

annular ligament
type: Class
subclass of: Restriction
  on property: part of
  some values from: tracheal cartilaginous ring
subclass of: Restriction
  on property: part of
  some values from: bronchial cartilaginous ring
has db xref: LMMA:00592
has db xref: UBERON:2002141
id: LMHA:00587
has domain: tissue

bronchiolar lamina propria
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: terminal bronchiolar wall
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar wall
id: LMHA:00589
has domain: anatomy
analogous to: LMMA:0525

bronchial lamina propria
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial mucosa
has db xref: LMMA:00481
has db xref: UBERON:0002338
id: LMHA:00590
definition: An epithelial cell that lines the trachea. The trachea is lined by pseudostratified columnar epithelial cells, including ciliated cells, club cells, basal cells, and neuroepithelial cells.
has domain: anatomy
synonym: bronchial connective tissue

bronchial cartilaginous ring
type: Class
subclass of: Restriction
  on property: part of
  some values from: bronchial submucosa
has db xref: LMMA:00133
id: LMHA:00595
has domain: anatomy
synonym: cartilage
synonym: cartilage ring
synonym: cartilaginous ring

proliferative interstitial cell
type: Class
subclass of: alveolar interstitial cell
subclass of: Restriction
  on property: part of
  some values from: alveolar interstitial tissue
id: LMHA:00598
display: true
has domain: cell

lymphoid cell
type: Class
subclass of: immune cell
has db xref: BTO:0001096
has db xref: LMMA:00614
id: LMHA:00614
has domain: cell

right apical bronchus
type: Class
subclass of: right lung segmental bronchus
has db xref: FMA:7398
id: LMHA:00616
display order: 1
has domain: anatomy
located in: RUL
synonym: tertiary bronchus

right lateral basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:7419
id: LMHA:00617
display order: 9
has domain: anatomy
located in: RLL
synonym: tertiary bronchus

right posterior basal bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:7420
id: LMHA:00618
display order: 10
has domain: anatomy
located in: RLL
synonym: tertiary bronchus

right lower lobe superior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
id: LMHA:00619
display order: 6
has domain: anatomy
synonym: tertiary bronchus

right posterior bronchus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right lung segmental bronchus
has db xref: FMA:7399
id: LMHA:00620
display order: 3
has domain: anatomy
located in: RUL
synonym: tertiary bronchus

erythrocyte
type: Class
subclass of: blood cell
has db xref: CL:0000232
has db xref: LMMA:00619
id: LMHA:00622
has domain: cell

innate lymphoid cell
type: Class
subclass of: lymphoid cell
has db xref: CL:0001065
has db xref: LMMA:00620
id: LMHA:00623
has domain: cell

lymphoid tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory immune system
has db xref: LMMA:00626
has db xref: UBERON:0001744
id: LMHA:00626
HTC code: LNH
HTC code: LNT
has domain: anatomy
synonym: bronchus-associated lymphoid tissue (BALT)
synonym: secondary lymphoid tissue
comment: variably present in postnatal life , typically reactive conditions

respiratory bronchiolar epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory bronchiolar epithelium
id: LMHA:00629
has domain: cell
analogous to: LMMA:0582

membranous bronchiolar epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: membranous bronchiolar epithelium
id: LMHA:00630
has domain: cell
analogous to: LMMA:0582

intra-parenchymal blood vessel
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary blood vessel
has db xref: LMMA:00632
id: LMHA:00632
display: true
display order: 3
has domain: anatomy

pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory autonomic nervous system
has db xref: LMMA:00633
has db xref: UBERON:0002009
id: LMHA:00633
display: true
has domain: anatomy
comment: extrapulmonary plexus; associated with left and right bronchi at root of left and right lung in mediastinum

pulmonary autonomic ganglion
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory autonomic nervous system
has db xref: LMMA:00634
id: LMHA:00634
display: true
has domain: anatomy
synonym: nerve cell cluster
comment: intrapulmonary; adjacent to bronchi and blood vessels

left pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary nerve plexus
has db xref: FMA:223443
has db xref: LMMA:00635
id: LMHA:00635
display: true
has domain: anatomy

left anterior pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left pulmonary nerve plexus
has db xref: FMA:6657
has db xref: LMMA:00636
id: LMHA:00636
display: true
has domain: anatomy

left posterior pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: left pulmonary nerve plexus
has db xref: FMA:6659
has db xref: LMMA:00637
id: LMHA:00637
display: true
has domain: anatomy

right pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary nerve plexus
has db xref: FMA:223441
has db xref: LMMA:00638
id: LMHA:00638
display: true
has domain: anatomy

right anterior pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right pulmonary nerve plexus
has db xref: FMA:6656
has db xref: LMMA:00639
id: LMHA:00639
display: true
has domain: anatomy

right posterior pulmonary nerve plexus
type: Class
subclass of: Restriction
  on property: part of
  some values from: right pulmonary nerve plexus
has db xref: FMA:6658
has db xref: LMMA:00640
id: LMHA:00640
display: true
has domain: anatomy

pulmonary autonomic nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory autonomic nervous system
has db xref: LMMA:00641
id: LMHA:00641
display: true
has domain: anatomy

preganglionic parasympathetic nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: pulmonary autonomic nerve
has db xref: LMMA:00642
has db xref: UBERON:0011930
id: LMHA:00642
display: true
has domain: anatomy

general visceral nervous system
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory autonomic nervous system
has db xref: FMA:9905
has db xref: LMMA:00643
id: LMHA:00643
display: true
has domain: anatomy

general visceral afferent nerve
type: Class
subclass of: Restriction
  on property: part of
  some values from: general visceral nervous system
has db xref: FMA:80114
has db xref: LMMA:00644
id: LMHA:00644
display: true
has domain: anatomy
synonym: sensory nerve

visceral afferent sensory nerve terminal
type: Class
subclass of: Restriction
  on property: part of
  some values from: general visceral afferent nerve
has db xref: LMMA:00645
id: LMHA:00645
display: true
has domain: anatomy
synonym: visceral afferent sensory nerve receptor

bronchus-associated lymphoid tissue
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymphoid tissue
has db xref: LMMA:00475
has db xref: MA:0000135
id: LMHA:00651
has domain: anatomy
synonym: BALT
comment: variably present in postnatal life , typically reactive conditions

connective tissue capsule
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymph node
has db xref: LMMA:00678
id: LMHA:00678
has domain: tissue

trabecula
type: Class
subclass of: Restriction
  on property: part of
  some values from: connective tissue capsule
has db xref: LMMA:00679
has db xref: UBERON:0000440
id: LMHA:00679
has domain: tissue

cortex
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymph node
has db xref: LMMA:00680
has db xref: UBERON:0001851
id: LMHA:00680
has domain: tissue

mucosa-associated lymphoid tissue macrophage
type: Class
subclass of: macrophage
subclass of: Restriction
  on property: part of
  some values from: medullary cord
has db xref: CL:0000868
has db xref: LMMA:00698
id: LMHA:00681
has domain: cell

medulla
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymph node
has db xref: FMA:61108
has db xref: LMMA:00682
id: LMHA:00682
has domain: tissue

medullary cord
type: Class
subclass of: Restriction
  on property: part of
  some values from: medulla
has db xref: LMMA:00683
has db xref: UBERON:0009745
id: LMHA:00683
has domain: tissue

reticular cell
type: Class
subclass of: connective tissue cell
subclass of: Restriction
  on property: part of
  some values from: reticular fiber
subclass of: Restriction
  on property: part of
  some values from: paracortex
id: LMHA:00685
has domain: cell

endothelial sinus
type: Class
subclass of: Restriction
  on property: part of
  some values from: lymph node
has db xref: LMMA:00686
has db xref: MESH:D042783
id: LMHA:00686
has domain: tissue

cortical sinus
type: Class
subclass of: Restriction
  on property: part of
  some values from: endothelial sinus
has db xref: LMMA:00687
id: LMHA:00687
has domain: tissue

medullary sinus
type: Class
subclass of: Restriction
  on property: part of
  some values from: endothelial sinus
has db xref: LMMA:00688
has db xref: UBERON:0009744
id: LMHA:00688
has domain: tissue

paratrabecular sinus
type: Class
subclass of: Restriction
  on property: part of
  some values from: endothelial sinus
has db xref: LMMA:00689
id: LMHA:00689
has domain: tissue
synonym: trabecular sinus

subcapsular sinus
type: Class
subclass of: Restriction
  on property: part of
  some values from: endothelial sinus
has db xref: LMMA:00690
has db xref: UBERON:0005463
id: LMHA:00690
has domain: tissue

blood cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: respiratory vascular system
has db xref: CL:0000081
has db xref: LMMA:00692
id: LMHA:00692
has domain: cell

submucosal gland duct epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: submucosal gland duct epithelium
id: LMHA:00693
has domain: cell

submucosal gland epithelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: submucosal gland epithelium
id: LMHA:00694
has domain: cell

arterial endothelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: arteriole endothelium
subclass of: Restriction
  on property: part of
  some values from: artery endothelium
has db xref: BTO:0004758
id: LMHA:00804
HTC code: END
definition: An endothelial cell of the atrerial blood vessels.
display: true
has domain: cell

venous endothelial cell
type: Class
subclass of: Restriction
  on property: part of
  some values from: vein endothelium
subclass of: Restriction
  on property: part of
  some values from: venule endothelium
has db xref: BTO:0001176
id: LMHA:00805
HTC code: END
definition: An endothelial cell of the venous blood vessels.
display: true
has domain: cell

alveolar sac
type: Class
subclass of: left upper lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right lower lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right middle lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: right upper lobe alveolar parenchyma
subclass of: Restriction
  on property: part of
  some values from: left lower lobe alveolar parenchyma
has db xref: LMMA:00817
has db xref: UBERON:0002169
display: true
display order: 2
has domain: anatomy

alveolar sac lumen
type: Class
subclass of: Restriction
  on property: part of
  some values from: alveolar sac
has db xref: LMMA:00818
display: true
has domain: anatomy