STMSO
type: Ontology
comment: STMSO is an OWL 2 ontology for symptomatic treatment for multiple sclrosis patients. The ontology is based on BFO and OGMS.
creator: Misagh Zahiri Esfahani
date: 2021

Should be used
type: ObjectProperty
comment: used for EDSS evaluation

Entity
type: Class
comment: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81

continuant
type: Class
subclass of: Entity
comment: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240

occurrent
type: Class
subclass of: Entity
comment: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region

independent continuant
type: Class
subclass of: Entity
comment: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])

process
type: Class
subclass of: occurrent
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])

specifically dependent continuant
type: Class
subclass of: continuant
comment: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])

material entity
type: Class
subclass of: independent continuant
definition: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])

Hippotherapy
type: Class
subclass of: Rehabilitation
comment: Hippotherapy is a form of physical, occupational and speech therapy in which a therapist uses the characteristic movements of a horse to provide carefully graded motor and sensory input.

Acquired pendular nystagmus
type: Class
subclass of: Nystagmus
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Baclofen
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dalfampridine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Fampridine
comment: Acquired_pendular_nystagmus

Actionable Bladder Symptom and Screening Tool
type: Class
subclass of: Measurement index
comment: ABSST: Actionable Bladder Symptom and Screening Tool

Acupuncture
type: Class
subclass of: chinese medicine
synonyme: needling

Adjust your activity levels
type: Class
subclass of: Recommendation for fatigue problems
comment: Save energy for what matters most to you. Set priorities, then focus on them. Cut out low-priority tasks

Ankle-foot orthosis
type: Class
subclass of: Orthotic devices
comment: AFO: Ankle-foot orthosis

Attention and concentration
type: Class
subclass of: Cognitive Problems
subclass of: Restriction
  on property: Has recommendation
  some values from: Practice focusing on one thing at a time
type: NamedIndividual
comment: The decrease in amount of time that a person can concentrate on a task without becoming distracted.

Barrow Neurological Institute
type: Class
subclass of: Measurement index
comment: Barrow Neurological Institute (BNI)

Bowel disturbance
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has surgery
  some values from: Cholostomy
comment: bladder

breathing problems
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Continuous Positive Airway Pressure
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Physical therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Pulmonary
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Vestibular rehabilitation
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Carisoprodol
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Cyclobenzaprine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Invasive ventilator
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Metaxalone
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Non-invasive ventilator
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Ventilator
synonyme: Respiration
definition: breathing is primarily under the control of the autonomic or “automatic” nervous system — the part of the central nervous system that controls vital functions such as heartbeat and respiration without conscious thought. It is unusual for MS to affect the autonomic nervous system, and therefore uncommon for breathing problems to occur in MS as a direct result of loss of autonomic control.

Brief International Cognitive Assessment for Multiple Sclerosis
type: Class
subclass of: Measurement index
disjoint with: 25 Feet Walk Test
comment: Brief International Cognitive Assessment for Multiple Sclerosis

Brief Neuropsychological Battery
type: Class
subclass of: Measurement index
comment: BNB: Brief Neuropsychological Battery

Brief Repeatable Neuropsychological Battery
type: Class
subclass of: Measurement index
comment: Brief Repeatable Neuropsychological Battery (BRNB)

Brush your teeth and tongue thoroughly twice a day
type: Class
subclass of: Recommendation for dysphagia
comment: found to be the single most important factor for reducing aspiration pneumonia because it reduces bacteria in the mouth

CCTV
type: Class
subclass of: Optical device
comment: Closed Circuit Television

Changing positions
type: Class
subclass of: Minimize spasticity
comment: e.g., lying on one side with the partner approaching from behind

Cognitive Problems
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Cognitive rehabilitation
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Donepezil
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Rivastigmine
subclass of: Restriction
  on property: Has recommendation
  some values from: Getting enough sleep
definition: rdfs:isDefinedBy "Problems with concentration/attention, memory impairment, poor word-finding ability, decreased information-processing speed, motor slowing and mental exhaustion. "

Complementary_treatment
type: Class
subclass of: treatment plan
subclass of: Restriction
  on property: has order
  has value: 2
definition: Complementary medicine is a term used to describe types of treatments you may receive along with traditional Western medicine.

Computerized Speed Cognitive Test
type: Class
subclass of: Measurement index
comment: CSCT: Computerized Speed Cognitive Test

Continuous Positive Airway Pressure
type: Class
subclass of: Assistive devices
comment: CPAP

Diplopia
type: Class
subclass of: Vision Problems
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Fresnel
subclass of: Restriction
  on property: Has recommendation
  some values from: Resting or cooling down the eye
subclass of: Restriction
  on property: Has recommendation
  some values from: Short-term patching of one eye
subclass of: Restriction
  on property: Has surgery
  some values from: Diplopia surgery
comment: Double vision A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS, STRABISMUS, OCULOMOTOR NERVE DISEASES, TROCHLEAR NERVE DISEASES, ABDUCENS NERVE DISEASES, and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Double swallows may be recommended
type: Class
subclass of: Recommendation for dysphagia
comment: Swallow once to send the liquid or food down, followed by a dry swallow to clear any residual or particles.

Drink cool liquids
type: Class
subclass of: Recommendation for fatigue problems
comment: Chilled drinks, ices, and popsicles help keep your body’s temperature in the comfort zone. Make sure you get plenty of water during the day, no matter what else you drink.

Dysarthria problems
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Speech therapy rehabilitation
subclass of: Restriction
  on property: Has recommendation
  some values from: Awareness of the body posture
subclass of: Restriction
  on property: Has recommendation
  some values from: Facing the partner while communicating
subclass of: Restriction
  on property: Has recommendation
  some values from: Reduction of background noise
subclass of: Restriction
  on property: Has recommendation
  some values from: Speaking half words on each breath
subclass of: Restriction
  on property: Has special test
  some values from: Fiberoptic Endoscopic Evaluation of Swallowing
subclass of: Restriction
  on property: Has special test
  some values from: Modified Barium Swallow
subclass of: Restriction
  on property: Has surgery
  some values from: Velopharyngeal surgery
comment: Dysphonia

Dysphagia
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Functional dysphagia therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Neuromuscular electrical stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Percutaneous Electrical Nerve Stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Percutaneous Endoscopic Gastrostomy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Resistance training
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Speech therapy rehabilitation
subclass of: Restriction
  on property: Has recommendation
  some values from: Brush your teeth and tongue thoroughly twice a day
subclass of: Restriction
  on property: Has recommendation
  some values from: Clear your throat and swallow again
subclass of: Restriction
  on property: Has recommendation
  some values from: Double swallows may be recommended
subclass of: Restriction
  on property: Has recommendation
  some values from: Keep the chin parallel with the table
subclass of: Restriction
  on property: Has recommendation
  some values from: Sit upright when eating or drinking
subclass of: Restriction
  on property: Has recommendation
  some values from: Take one small bite or sip at a time
subclass of: Restriction
  on property: Has special test
  some values from: Fiberoptic Endoscopic Evaluation of Swallowing
subclass of: Restriction
  on property: Has special test
  some values from: Modified Barium Swallow
synonyme: swallowing disorders
definition: Dysphagia is defined as any difficulty in swallowing function. The dysphagia is estimated in one-third of the patients with MS

EMG biofeedback
type: Class
subclass of: Rehabilitation
comment: Electromyographic biofeedback

ERT
type: Class
subclass of: Hormone replacement therapy
comment: Estrogen replacement therapy

Eat a healthy diet
type: Class
subclass of: Recommendation for fatigue problems
comment: Eating a well-balanced, low-fat diet, with plenty protein and adequate fluids, energizes your body. Try eating breakfast soon after you get up. Consult with a professional about an appropriate diet.

Emotional Disorders
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Group therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Meditation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Mindfulness
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Yoga
subclass of: Restriction
  on property: Has special test
  some values from: QOL
subclass of: Restriction
  on property: Has special test
  some values from: SF-36
subclass of: Restriction
  on property: Has special test
  some values from: Tolerability
synonyme: mood change
definition: MS can cause significant anxiety, distress, anger, and frustration from the moment of its very first symptoms.

Emptying dysfunction
type: Class
subclass of: Urinary disordesr
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Self-Catheterization
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Timed voiding
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Alfuzosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Doxazosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Prazosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Silodosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Tamsulosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Terazosin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Tizanidine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Baclofen (Intrathecal)
subclass of: Restriction
  on property: Has special test
  some values from: Post-Void Residual
comment: Failure to empty

Epworth Sleepiness Scale
type: Class
subclass of: Measurement index
comment: ESS: Epworth Sleepiness Scale

External Urine Collection Devices
type: Class
subclass of: Assistive devices
comment: EUCD

Myokymia
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: OnabotulinumtoxinA
type: NamedIndividual
definition: Facial myokymia is a clinical sign that can occur as a manifestation of demyelinating lesions.

Fatigue
type: Class
subclass of: Symptom
type: NamedIndividual
is side effect of: Ocrelizumab
comment: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. (MeSH definition )

Fatigue Severity Scale
type: Class
subclass of: Measurement index
comment: The Fatigue Severity Scale (FSS)

Fecal Incontinence
type: Class
subclass of: Bowel disturbance
subclass of: side effect of drug
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Biperiden
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Propantheline
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Trihexyphenidyl
type: NamedIndividual
comment: Involuntary Bowel

Fiberoptic Endoscopic Evaluation of Swallowing
type: Class
subclass of: Measurement index
type: NamedIndividual
comment: FEES: Fiberoptic Endoscopic Evaluation of Swallowing

Functional Ambulatory Profile
type: Class
subclass of: Measurement index
comment: A Functional Ambulatory Profile (FAP) score can be obtained from the GAITRite system The GAITRite Functional Ambulation System consisting of a GAITRite walkway and clinical stride analyzer, is a simple and convenient way allowing a valid and reliable qualitative spatiotemporal gait analysis

Functional dysphagia therapy
type: Class
subclass of: Procedure
comment: (muscular function, swallowing techniques, adaptation of food consistency)
comment: Functional dysphagia therapy

GAITRite Functional Ambulation System
type: Class
subclass of: Measurement index
comment: The GAITRite Functional Ambulation System consisting of a GAITRite walkway and clinical stride analyzer, is a simple and convenient way allowing a valid and reliable qualitative spatiotemporal gait analysis

GTCS
type: Class
subclass of: Seizures
comment: Generalized Tonic-Clonic

Hearing loss
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has referrals to specialists
  some values from: audiologist
definition: Hearing loss is an uncommon symptom of MS. About 6 percent of people who have MS complain of impaired hearing. The cause of hearing loss can be due to non-MS related issues but in MS, can be associated with damage to the hearing nerve pathways in the brain and the brainstem.

Hormone replacement therapy
type: Class
subclass of: Non_pharmacological_treatment
comment: Hormone replacement therapy

Intention tremor
type: Class
subclass of: tremor
definition: This is a type of tremor seen in MS. It is generally greatest during physical movement; there is no shaking when a person is at rest.

Intermittent Theta Burst Stimulation
type: Class
subclass of: Stimulation
comment: iTBS

International Consultation on Incontinence-Urinary Incontinence
type: Class
subclass of: Measurement index
comment: ICIQ-UI: International Consultation on Incontinence-Urinary Incontinence

International Cooperative Ataxia Rating Scale
type: Class
subclass of: Measurement index
comment: ICARS: International Cooperative Ataxia Rating Scale

Intravenous pyelogram
type: Class
subclass of: Measurement index
comment: IVP: Intravenous pyelogram

Kinect-based virtual rehabilitation
type: Class
subclass of: Rehabilitation
comment: RemoviEM

Kings Health Questionnaire
type: Class
subclass of: Measurement index
comment: KHQ: Kings Health Questionnaire

Lab_monitoring
type: Class
subclass of: treatment plan

Lower Urinary Tract Dysfunction
type: Class
subclass of: Urinary tract dysfunction
subclass of: Restriction
  on property: Has special test
  some values from: Cystoscopy
comment: Lower Urinary Tract Dysfunction

Measurement index
type: Class
subclass of: process
comment: Measurement index
definition: Tools and questioners that are used to better understanding of MS symptoms.

Memory
type: Class
subclass of: Cognitive Problems
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Brain stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Counseling
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Cryostimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Mind game with puzzles
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Occupational therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Psychotherapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Speech therapy rehabilitation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Stress management
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Video games
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Yoga
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dalfampridine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Ginkgo
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Memantine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Methylphenidate
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Turmeric
subclass of: Restriction
  on property: Has recommendation
  some values from: Memory aids
subclass of: Restriction
  on property: Has recommendation
  some values from: Posting notes on the refrigerator
subclass of: Restriction
  on property: Has recommendation
  some values from: Use mental pictures
subclass of: Restriction
  on property: Has recommendation
  some values from: Writing things down in notebooks
subclass of: Restriction
  on property: Has special test
  some values from: Brief Neuropsychological Battery
comment: recall A disorder characterized by systematic and extensive loss of memory.

Minimal Assessment of Cognitive Function in MS
type: Class
subclass of: Measurement index
comment: MACFIMS: Minimal Assessment of Cognitive Function in MS

Modified Ashworth Scale
type: Class
subclass of: Measurement index
comment: MAS: Modified Ashworth Scale

Modified Barium Swallow
type: Class
subclass of: Measurement index
type: NamedIndividual
comment: MBS: Modified Barium Swallow

Multiple Sclerosis Neuropsychological Screening Questionnaire
type: Class
subclass of: Measurement index
comment: Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ)

Muscle spasms
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has complementary treatment
  some values from: Acupuncture
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Ankle-foot orthosis
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Balance and coordination
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Cooling strategies
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Hydrotherapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Kinect-based virtual rehabilitation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Occupational therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Physical therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Repetitive Transcranial Magnetic Stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Repetitive magnetic stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Strengthening
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Tenotomy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Transcutaneous Electrical Nerve Stimulation
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Wheelchair
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Whole Body Vibration
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Baclofen
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Cannabis sativa L
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dantrolene
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Diazepam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Gabapentin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Nabilone
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Nabiximols
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: OnabotulinumtoxinA
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Phenol
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Tizanidine
subclass of: Restriction
  on property: Has recommendation
  some values from: Changing positions
subclass of: Restriction
  on property: Has special test
  some values from: Modified Ashworth Scale
subclass of: Restriction
  on property: Has surgery
  some values from: Neurectomy
subclass of: Restriction
  on property: Has surgery
  some values from: Rhizotomy
refrence: Muscle stiffness and spasms are common MS symptoms, and are often described as 'spasticity'. Muscle spasms or stiffness can affect between 40% and 80% of people with MS at some time. For most people, these are occasional symptoms.
synonyme: spasticity

Music therapy
type: Class
subclass of: Complementary_treatment
definition: Music therapy is the clinical use of music to accomplish individualized goals such as reducing stress, improving mood and self-expression. It is an evidence-based therapy well-established in the health community. Music therapy experiences may include listening, singing, playing instruments, or composing music.

Neurogenic Bladder Symptom Score
type: Class
subclass of: Measurement index
comment: NBSS: Neurogenic Bladder Symptom Score

Neuromuscular electrical stimulation
type: Class
subclass of: Stimulation
comment: NEMS: Neuromuscular electrical stimulation

Non_pharmacological_treatment
type: Class
subclass of: treatment plan
subclass of: Restriction
  on property: has order
  has value: 2

Nystagmus
type: Class
subclass of: Vision Problems
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Amitriptyline
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Gabapentin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Memantine
comment: Nystagmus is uncontrolled horizontal and vertical involuntary abnormal eye movement, which persists especially when a person looks to the side.

Optical device
type: Class
subclass of: Assistive devices
comment: such as microscopic or telescopic eyewear, a magnifier, a filter or a closed circuit television (CCTV) system.

Oral sex
type: Class
subclass of: Minimize weakness
comment: Oral sex requires less movement than intercourse

Overactive Bladder Questionnaire
type: Class
subclass of: Measurement index
comment: OAB-Q; Overactive Bladder Questionnaire

Pain
type: Class
subclass of: Symptom
definition: Pain can be associated with stiffness or spasms in muscles, or symptoms like Lhermitte's sign, trigeminal neuralgia or optic neuritis. It may also include symptoms affecting the senses that are not always thought of as ‘pain’, like numbness or pins and needles, or a tightness in the chest known as the 'MS hug' or 'MS girdle'. Pain can be one of the most difficult 'invisible’ symptoms to describe and manage. Only the person experiencing it knows how it feels. It has an emotional element – it can cause distress, fear, anger and frustration, which in turn affect how you deal with it.

Percutaneous Electrical Nerve Stimulation
type: Class
subclass of: Stimulation
comment: PENS: Percutaneous Electrical Nerve Stimulation

Percutaneous Endoscopic Gastrostomy
type: Class
subclass of: Procedure
comment: PEG: Percutaneous Endoscopic Gastrostomy

Percutaneous Tibial Nerve Stimulation
type: Class
subclass of: Stimulation
comment: PTNS

Pharmacological treatment
type: Class
subclass of: drug
subclass of: Restriction
  on property: Has side effect
  some values from: Somnolence
subclass of: Restriction
  on property: Has side effect
  some values from: increased appetite
subclass of: Restriction
  on property: Has side effect
  some values from: nausea
subclass of: Restriction
  on property: Has side effect
  some values from: vomiting
subclass of: Restriction
  on property: has order
  has value: 1

Pittsburgh Sleep Quality Index
type: Class
subclass of: Measurement index
comment: PSQI: Pittsburgh Sleep Quality Index

Plan your day around your natural body rhythms
type: Class
subclass of: Recommendation for fatigue problems
comment: Schedule your must-do activities for your most energetic times. To help you sleep, drink warm milk 30 minutes before bedtime. Keep exercise equipment and TVs out of the bedroom. If you’ve been trying to fall asleep for more than 30 minutes, get out of the bed and do a quiet activity until you feel tired.

Plates and cups with lips
type: Class
subclass of: Assistive devices
comment: plates and cups with lips minimize food spills

Post-Void Residual
type: Class
subclass of: Measurement index
comment: PVR: Post-Void Residual

Postural tremor
type: Class
subclass of: tremor
definition: This type of tremor is generally the greatest when a limb or the whole body is being supported against gravity. For example, a person who has a postural tremor will shake while sitting or standing, but not while lying down.

Prayer therapy
type: Class
subclass of: Complementary_treatment
definition: prayer therapy is a type of treatment for medical or psychological conditions that is focused on using prayer as the main method.

Processing Speed Test
type: Class
subclass of: Measurement index
comment: Processing Speed Test (PST)

Pseudobulbar affect
type: Class
subclass of: Emotional Disorders
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Citalopram
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dextromethorphan
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Fluoxetine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Fluvoxamine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Paroxetine
comment: Affect disorders Euphoria

Recommendations
type: Class
subclass of: treatment plan

Repetitive Transcranial Magnetic Stimulation
type: Class
subclass of: Stimulation
comment: rTMS

Resting tremor
type: Class
subclass of: tremor
definition: generally is greatest when the body part is at rest and is diminished with movement. This type of tremor is more typical of Parkinson's disease than MS.

SF-36
type: Class
subclass of: Measurement index
definition: SF-36 is a set of generic, coherent, and easily administered quality-of-life measures. These measures rely upon patient self-reporting and are now widely utilized by managed care organizations and by Medicare for routine monitoring and assessment of care outcomes in adult patients.

Seizures
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Carbamazepine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Gabapentin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Lamotrigine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Levetiracetam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Phenytoin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Pregabalin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Valproic acid
type: NamedIndividual
definition: Seizures, which are the result of abnormal electrical discharges in an injured or scarred area of the brain, are fairly uncommon in MS.

Self-Catheterization
type: Class
subclass of: Self managment
comment: CIC (Clean Intermittent Catheterization) or intermittent self -catheterization (ISC)

Sex therapist
type: Class
subclass of: Refer to
comment: couples counselor

Sexual dysfunction
type: Class
subclass of: Symptom
comment: Sexual activities of humans.
definition: Sexual dysfunction is common in people with MS and is important to assess because patients may be reluctant to self-report. Both men and women with MS may experience difficulty achieving orgasm or loss of libido.

Sleep Disorders
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Clonazepam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Lorazepam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Pramipexole
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Zolpidem
subclass of: Restriction
  on property: Has special test
  some values from: Epworth Sleepiness Scale
subclass of: Restriction
  on property: Has special test
  some values from: Pittsburgh Sleep Quality Index
definition: Conditions characterized by disturbances of usual sleep patterns or behaviors. (Source: http://www.ncbi.nlm.nih.gov/mesh/68012893 )

Stay cool
type: Class
subclass of: Recommendation for fatigue problems
comment: Lowering your body temperature helps you feel refreshed. Cool showers, air conditioning, swimming or pool therapy in cool water, lightweight clothes, and cooling equipment can help you beat the heat

Stop smoking
type: Class
subclass of: Recommendation for fatigue problems
comment: Smoking puts a strain on your lungs, making fatigue worse and compounding the effects of MS. Quit the habit , and breathing and simple activities may not tire you out so much.

Storage dysfunction
type: Class
subclass of: Urinary disordesr
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Bladder retraining
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: External Urine Collection Devices
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Kegel
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Pessary
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Darifenacin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Desipramine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Fesoterodine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Hyoscyamine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Imipramine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Mirabegron
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Oxybutynin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Propantheline
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Tolterodine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Trospium
subclass of: Restriction
  on property: Has special test
  some values from: Post-Void Residual
comment: Failure to store

Surgery
type: Class
subclass of: treatment plan
subclass of: Restriction
  on property: has order
  has value: 3

Symbol Digit Modalities Test
type: Class
subclass of: Measurement index
comment: SDMT: Symbol Digit Modalities Test

Symptom
type: Class
subclass of: Entity
comment: rdfs:isDefinedBy "\"A perceived change in function, sensation or appearance reported by a patient indicative of a disease\"."^^xsd:string
refrence: https://uts.nlm.nih.gov/uts.html

Take naps
type: Class
subclass of: Recommendation for fatigue problems
comment: Naps give tired muscles a break and pump energy back into your system. A nap for 10–30 minutes can help.

Traditional medicine
type: Class
subclass of: Complementary_treatment
definition: It is the sum total of the knowledge, skill, and practices based on the theories, beliefs, and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness.

Transcutaneous Electrical Nerve Stimulation
type: Class
subclass of: Stimulation
comment: TENS

tremor
type: Class
subclass of: Symptom
subclass of: side effect of drug
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Braces
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Plates and cups with lips
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Wrist rests
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Alprazolam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Baclofen
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Carbamazepine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Clonazepam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Divalproex sodium
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Gabapentin
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Isoniazid
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Levetiracetam
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Primidone
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Propranolol
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Topiramate
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Trihexyphenidyl
subclass of: Restriction
  on property: Has recommendation
  some values from: Weighted boots
subclass of: Restriction
  on property: Has recommendation
  some values from: Weighted spoons or forks
subclass of: Restriction
  on property: Has recommendation
  some values from: Weights fastened
subclass of: Restriction
  on property: Has special test
  some values from: International Cooperative Ataxia Rating Scale
subclass of: Restriction
  on property: Has special test
  some values from: Mental QOL
subclass of: Restriction
  on property: Has special test
  some values from: Physical QOL
subclass of: Restriction
  on property: Has special test
  some values from: SF-12 score
subclass of: Restriction
  on property: Has special test
  some values from: Tremor Rating Scale
subclass of: Restriction
  on property: Has special test
  some values from: Tremor and Coordination Scale
subclass of: Restriction
  on property: Has surgery
  some values from: Thalamotomy
type: NamedIndividual
is side effect of: Ocrelizumab
definition: A tremor can be described as a rhythmic trembling or shaking movement that you cannot control voluntarily. (https://www.mssociety.org.uk/about-ms/signs-and-symptoms/tremor)

Tremor Rating Scale
type: Class
subclass of: Measurement index
comment: Tremor Rating Scale (TRS)

Tremor and Coordination Scale
type: Class
subclass of: Measurement index
comment: TACS: Tremor and Coordination Scale

Uhthoff phenomenon
type: Class
subclass of: Symptom
definition: Uhthoff phenomenon, also known as Uhthoff sign or Uhthoff syndrome, is a transient worsening of neurological function lasting less than 24 hours that can occur in multiple sclerosis patients due to increases in core body temperature. (https://www.ncbi.nlm.nih.gov/books/NBK470244/)

Upper Urinary Tract
type: Class
subclass of: Urinary tract dysfunction
subclass of: Restriction
  on property: Has special test
  some values from: Cystoscopy
comment: Upper Urinary Tract

Urinary disordesr
type: Class
subclass of: Symptom
comment: Bladder disturbance

Urodynamic studies
type: Class
subclass of: Measurement index
comment: UDS: Urodynamic studies

Vertigo
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Occupational therapy
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Vestibular rehabilitation
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Betahistine Hydrochloride
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dimenhydrinate
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Diphenhydramine
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Meclizine
synonyme: Dizziness
definition: vetigo is a common symptom of MS. People with MS may feel off balance or lightheaded. Much less often, they have the sensation that they or their surroundings are spinning — a condition known as vertigo. These symptoms are due to lesions — damaged areas — in the complex pathways that coordinate visual, spatial and other input to the brain needed to produce and maintain equilibrium (balance).

Vision Problems
type: Class
subclass of: Symptom
synonyme: Visual Impairment
definition: rdfs:isDefinedBy "The absence of vision where it existed before. (Source: http://encyclopedia.thefreedictionary.com/vision+loss )"

Vitamin B1
type: Class
subclass of: Dietary supplementss
comment: Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism of fatty acids of odd-chain length and in methyl transfer. (DRI)

Vitamin B12
type: Class
subclass of: Dietary supplementss
comment: Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism of fatty acids of odd-chain length and in methyl transfer. (DRI)

Walking difficulties
type: Class
subclass of: Symptom
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Scooter
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Wheelchair
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dalfampridine
definition: Ambulation Problems or Gait difficulties Impairment of the ability to coordinate the movements required for normal ambulation (walking) which may result from impairments of motor function or sensory feedback. (Source: http://www.ncbi.nlm.nih.gov/mesh?term=gait%20ataxia )

weakness
type: Class
subclass of: Symptom
subclass of: side effect of drug
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Assistive devices
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Exercise
subclass of: Restriction
  on property: Has nonpharmacological treatment
  some values from: Occupational therapy
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Dalfampridine
definition: Weakness is a common symptom in multiple sclerosis. You may feel that you do not have enough strength or energy to move some or all of your limbs, or your whole body. Weakness and fatigue are closely linked and having one often makes the other symptoms worse.

Weights fastened
type: Class
subclass of: Assistive devices
comment: Weights fastened to the wrists or ankles with Velcro strips can stabilize an affected limb.

Wrist rests
type: Class
subclass of: Assistive devices
comment: Adaptive equipment, such as wrist rests that facilitate writing or typing

constipation
type: Class
subclass of: Bowel disturbance
subclass of: side effect of drug
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Docusate
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Laxatives
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Magnesium hydroxide
subclass of: Restriction
  on property: Has pharmacological treatment
  some values from: Polyethylene glycol 3350
type: NamedIndividual
is side effect of: Dimethyl fumarate
comment: Infrequent or difficult evacuation of feces. (Source: http://www.ncbi.nlm.nih.gov/mesh?term=constipation )

lidocaine
type: Class
subclass of: Pharmacological treatment
comment: Intranasal lidocaine

treatment plan
type: Class
subclass of: process
label: treatment plan

25 Feet Walk Test
type: Class
subclass of: Measurement index
comment: 25FWT: The 25 Feet Walk Test

Credé’s Maneuver
type: Class
subclass of: Behavioral self-management
comment: involves using ones’ hands to produce downward suprapubic bladder pressure to effectively empty a neurogenic bladder.

F1
type: NamedIndividual
comment: Is fatigue present?

F2
type: NamedIndividual
comment: If possible, eliminate/reduce medications

F3
type: NamedIndividual
comment: Is depression evident?

F4
type: NamedIndividual
comment: Treat depression with psychotherapy and/or antidepressants(s)

F5
type: NamedIndividual
comment: Consider nonpharmacological interventions Education (patient and caregiver) Life style modification (exercise and diet) Energy conservation and pacing strategies Work simplification strategies Environmental modification (adaptive aids e.g., cooling vests)

B9
type: NamedIndividual
comment: Anticholinergics (must monitor bladder function)

C1
type: NamedIndividual
comment: Medications causing or contributing?

C2
type: NamedIndividual
comment: Adjust medications

C3
type: NamedIndividual
comment: Urinary Symptoms Controlled?

C4
type: NamedIndividual
comment: Treat bladder symptoms

C5
type: NamedIndividual
comment: Early Interventions • 2 L fluid intake daily • Diet-fiber/bulk formers/sugar preparations • High fiber balanced diet • Physical activity • Regular time of evacuation Constipation relieved?

C6
type: NamedIndividual
comment: Sequential Trials • Stool softeners • Mild oral laxatives • Suppositories/digital stiumation • Enemas Constipation relieved?"

C7
type: NamedIndividual
comment: Refer to gastroenterologist

E1
type: NamedIndividual
comment: Is patient experiencing emotional symptoms? Do the symptoms suggest normal grieving?

E11
type: NamedIndividual
comment: Start treatment Pharmacotherapy: monitor for side effects, increase dose to therapeutic level Psychotherapy: build therapeutic alliance, discuss modality, frequency, goals Continue treatment Monitor for response Monitor for suicide Terminate treatment If in remission at least 12 months If low risk of recurrence Terminate treatment If in remission at least 12 months If low risk of recurrence

E2
type: NamedIndividual
comment: Do the symptoms meet criteria for an emotional disorder?

E3
type: NamedIndividual
comment: Is the patient suicidal or homicidal?

E4
type: NamedIndividual
comment: Continued observation. Education as needed

E5
type: NamedIndividual
comment: Hospitalize

E6
type: NamedIndividual
comment: Consult with a mental health profesional

IB1
type: NamedIndividual
comment: Diet: Caffeine? Alcohol?

IB2
type: NamedIndividual
comment: Eliminate dietary irritants IB relieved?

IB3
type: NamedIndividual
comment: Antispasticity Medication?

IB4
type: NamedIndividual
comment: Adjust medications IB relieved?

IB5
type: NamedIndividual
comment: Bulking agents IB relieved?

IB6
type: NamedIndividual
comment: Anticholinergics (must monitor bladder function) IB relieved?

IB7
type: NamedIndividual
comment: Refer to gastroenterologist

U10
type: NamedIndividual
comment: Surgery

U4
type: NamedIndividual
comment: measure of the PVR Significant degree of voiding dysfunction PVR> 100 ml

U5
type: NamedIndividual
comment: intermittent catheterization LUT dysfunction relieved?

U6
type: NamedIndividual
comment: PVR<100 ml

U7
type: NamedIndividual
comment: Antimuscarinic agent Trospium chloride Tolterodine Oxybutynin LUT dysfunction relieved?

U8
type: NamedIndividual
comment: Emerging treatment Mirabegron Neuromodulation LUT dysfunction relieved?

U9
type: NamedIndividual
comment: intradetrusor onabotulinumtoxinA injection LUT dysfunction relieved?

patient 1
type: NamedIndividual
type: Patient
has economic status: low
has underlying disease: Attention and concentration
has underlying disease: Dysarthria problem
has underlying disease: Myokymia
has underlying disease: Partial
should prescribe: Awareness of the body posture
should prescribe: Carbamazepine
should prescribe: Cognitive rehabilitation
should prescribe: Donepezil
should prescribe: Facing the partner while communicating
should prescribe: Fiberoptic Endoscopic Evaluation of Swallowing
should prescribe: Gabapentin
should prescribe: Getting enough sleep
should prescribe: Lamotrigine
should prescribe: Levetiracetam
should prescribe: Modified Barium Swallow
should prescribe: OnabotulinumtoxinA
should prescribe: Phenytoin
should prescribe: Practice focusing on one thing at a time
should prescribe: Pregabalin
should prescribe: Reduction of background noise
should prescribe: Rivastigmine
should prescribe: Speaking half words on each breath
should prescribe: Speech therapy rehabilitation
should prescribe: Valproic acid
should prescribe: Velopharyngeal surgery
has EDSS: 1

s1
type: NamedIndividual
comment: Removal of triggers, appropriate positioning, physiotherapy, occupational therapy, orthosis Requires drug treatment
version info: 1.2

s10
type: NamedIndividual
comment: Combined treatment baclofen + tizanidine Non-responder

s11
type: NamedIndividual
comment: Other possible combinations or intrathecal baclofen

s12
type: NamedIndividual
comment: Botox + physiotherapy adjuvant Bad Responder to treatment

s13
type: NamedIndividual
comment: Plaster mass-produced orthosis Bad Responder to treatment

s14
type: NamedIndividual
comment: Assess orthopedic surgery

s2
type: NamedIndividual
comment: No treatment

s3
type: NamedIndividual
comment: Type of spasticity

s4
type: NamedIndividual
comment: Focal/regional spasticity

s5
type: NamedIndividual
comment: Generalised spasticity

s6
type: NamedIndividual
comment: Fixed contracture

s7
type: NamedIndividual
comment: Dynamic contracture

s8
type: NamedIndividual
comment: Baclofen or tizanidine Non-responder

s9
type: NamedIndividual
comment: Add-on Sativex Non-responder

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

is rule enabled: true

S19
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Biperiden

S27
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Escitalopram

S31
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Isoniazid

S30
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Levetiracetam

S29
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Levofloxacin

S28
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mianserin

S15
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S26
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Sertraline

S25
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Sildenafil

S24
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Solifenacin

S23
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Tizanidine

S22
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Tolterodine

S16
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Trazodone

S21
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Vardenafil

S20
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Venlafaxine

S13
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Zolpidem

S84
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: pregnant
head: IndividualPropertyAtom
  property predicate: Should not prescribe
  argument1: patient
  argument2: Atenolol

S85
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: pregnant
head: IndividualPropertyAtom
  property predicate: Should not prescribe
  argument1: patient
  argument2: Cannabis sativa L

S86
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: pregnant
head: IndividualPropertyAtom
  property predicate: Should not prescribe
  argument1: patient
  argument2: Diazepam

S87
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: pregnant
head: IndividualPropertyAtom
  property predicate: Should not prescribe
  argument1: patient
  argument2: Imipramine

S36
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Bupropion

S37
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Carbamazepine

S40
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Citalopram

S38
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Fampridine

S32
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Imipramine

S43
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Imipramine

S46
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Isoniazid

S45
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Lamotrigine

S42
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Levothyroxine

S41
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Memantine

S44
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mianserin

S34
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S39
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Sertraline

S35
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Topiramate

S33
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: seizure disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Venlafaxine

S93
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has symptom
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Back pain
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Ocrelizumab

S95
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has symptom
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Fatigue
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Ocrelizumab

S94
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has symptom
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: tremor
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Ocrelizumab

S92
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has symptom
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Urinary tract infection
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Fingolimod

S102
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has underlying disease
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Diarrhea
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Dimethyl fumarate

S101
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has underlying disease
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Fecal Incontinence
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Dimethyl fumarate

S99
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has underlying disease
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Urinary tract infection
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Dimethyl fumarate

S103
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has underlying disease
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: constipation
head: IndividualPropertyAtom
  property predicate: Should be checked for side effect of
  argument1: http://www.semanticweb.org/lenovo/ontologies/2021/1/untitled-ontology-26#p
  argument2: Dimethyl fumarate

S4
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Citalopram

S5
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Clonazepam

S6
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Lorazepam

S12
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Oxybutynin

S9
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Pramipexole

S11
type: Imp
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
body: BuiltinAtom
  builtin: greaterThan
  arguments: age
  arguments: 60
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Zolpidem

S3
type: Imp
body: BuiltinAtom
  builtin: lessThan
  arguments: age
  arguments: 18
body: DatavaluedPropertyAtom
  property predicate: Has age
  argument1: patient
  argument2: age
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Botox

S91
is rule enabled: true
type: Imp
body: ClassAtom
  class predicate: Patient
  argument1: patient
body: BuiltinAtom
  builtin: lessThan
  arguments: edss
  arguments: 5
body: DatavaluedPropertyAtom
  property predicate: Has EDSS
  argument1: patient
  argument2: edss
head: IndividualPropertyAtom
  property predicate: Should be used
  argument1: patient
  argument2: Aerobic

S90
is rule enabled: true
type: Imp
body: ClassAtom
  class predicate: Patient
  argument1: patient
body: DatavaluedPropertyAtom
  property predicate: Has EDSS
  argument1: patient
  argument2: edss
body: BuiltinAtom
  builtin: lessThan
  arguments: edss
  arguments: 7
head: IndividualPropertyAtom
  property predicate: Should be used
  argument1: patient
  argument2: Endurance training

S89
is rule enabled: true
type: Imp
body: ClassAtom
  class predicate: Patient
  argument1: patient
body: DatavaluedPropertyAtom
  property predicate: Has EDSS
  argument1: patient
  argument2: edss
body: BuiltinAtom
  builtin: lessThan
  arguments: edss
  arguments: 7
head: IndividualPropertyAtom
  property predicate: Should be used
  argument1: patient
  argument2: Treadmill walking

S1
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: Partial
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Dalfampridine

S2
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: Seizures
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Baclofen

S51
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Atenolol

S48
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Baclofen

S52
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Cannabis sativa L

S54
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Diazepam

S53
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Fampridine

S55
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Imipramine

S49
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Levothyroxine

S47
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mianserin

S50
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: diabet disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S79
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Duloxetine

S75
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Hyoscyamine

S82
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Imipramine

S81
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Meclizine

S80
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mianserin

S83
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S78
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Sertraline

S77
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Topiramate

S76
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Trihexyphenidyl

S74
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: glaucoma disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Venlafaxine

S56
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Apomorphine

S58
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Atenolol

S59
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Biperiden

S8
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Desmopressin

S57
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S62
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Trazodone

S61
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Vardenafil

S60
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: heart disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Venlafaxine

S66
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Baclofen

S7
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Desmopressin

S64
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Hyoscyamine

S69
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Isoniazid

S71
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Levetiracetam

S65
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Mirtazapine

S68
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Sildenafil

S67
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Topiramate

S72
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Trazodone

S73
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Trihexyphenidyl

S63
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Vardenafil

S70
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: kidney disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Venlafaxine

S17
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Alfuzosin

S18
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Apomorphine

S14
is rule enabled: true
type: Imp
body: IndividualPropertyAtom
  property predicate: Has sickness
  argument1: patient
  argument2: liver disease
head: IndividualPropertyAtom
  property predicate: Should prescribe with caution
  argument1: patient
  argument2: Baclofen