A0A0F8V8L2
type: Protein
reviewed: true
created: 2020-08-12
modified: 2023-02-22
version: 24
mnemonic: PROF1_LOKSG
citation: http://purl.uniprot.org/citations/25945739
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIPCBAECDA36DE15984
organism: http://purl.uniprot.org/taxonomy/1538547
annotation: SIP2611BEE4332C26FA
annotation: SIP217079BBAF9DC7A1
annotation: SIP373D1874D405282D
annotation: SIP5CFA8E0A43E02492
annotation: SIPA5DB3E85C3BB7F87
annotation: SIP6BD274A3D4E215BD
annotation: PRO_0000450549
annotation: SIP0ECE485AD5A98D12
annotation: SIPE7D0F85A3F60C67C
annotation: SIP154637399580902B
annotation: SIPA1E9B1D92B45DC98
annotation: SIP1D1B04E864A11274
annotation: SIPE0CE8448CD1C66ED
annotation: SIP195AF19BBCB5B014
annotation: SIP3E15ACC656BC15E5
annotation: SIP5B405B173E3ECBF1
annotation: SIP6B4820CE5396C9B3
annotation: SIP4DDBF50D658EF186
annotation: SIP141B982DFB398684
annotation: SIPCC6C28E99E5D2C4D
annotation: SIP907F0BE6D84E3974
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/9
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
classified with: GO_0003779
sequence: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI
proteome: Unassembled WGS sequence

A0A0F8V8L2-citation-25945739
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

GC14_75
type: Strain

A0A0F8V8L2-citation-30283132
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) ALONE AND IN COMPLEX WITH RABBIT ACTIN
scope: FUNCTION
scope: ACTIVITY REGULATION
scope: SUBCELLULAR LOCATION
scope: DOMAIN

5YED
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.60
chain sequence mapping: PDB 5YED tt1tt134

PDB 5YED tt1tt134
chain: A=1-134

5YEE
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.81
chain sequence mapping: PDB 5YEE tt1tt134

PDB 5YEE tt1tt134
chain: A=1-134

http://purl.uniprot.org/gene3d/3.30.450.30
type: Resource
database: Gene3D
comment: Dynein light chain 2a, cytoplasmic
signature sequence match: Gene3D 3.30.450.30 match 1

IPR036140
type: Resource
database: InterPro
comment: PFN_sf

SSF55770
type: Resource
database: SUPFAM
comment: Profilin (actin-binding protein)
signature sequence match: SUPFAM SSF55770 match 1

SIPCBAECDA36DE15984
type: Structured Name
full name: Loki profilin-1

http://purl.uniprot.org/uniprot/A0A0F8V8L2#gene-MD51F0DDAAD3F8293CC33A6E6B5D8CA220A
type: Gene
orf name: Lokiarch_47830

SIP2611BEE4332C26FA
type: Function Annotation
comment: Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.

SIP217079BBAF9DC7A1
type: Activity Regulation Annotation
comment: Inhibition of rabbit actin polymerization is reduced by phosphatidylinositol-(4,5)-P2(1,2-dipalmitoyl), a soluble form of the phospholipid phosphatidylinositol, suggesting an unknown lipid might regulate actin-profilin interaction in vivo.

SIP5CFA8E0A43E02492
type: Domain Annotation
comment: The Loki loop (specific to some members) becomes ordered on binding to rabbit actin.

SIPA5DB3E85C3BB7F87
type: Annotation
comment: It is not clear if Loki profilins 1, 2 and 3 are from the same strain.

SIP6BD274A3D4E215BD
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450549
type: Chain Annotation
comment: Loki profilin-1
mass: 14701
range: -9218585413503481810tt1tt134

-9218585413503481810tt1
type: Position
type: ExactPosition
position: 1
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt134
type: Position
type: ExactPosition
position: 134
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

SIP0ECE485AD5A98D12
type: Region Annotation
comment: Loki loop
range: -9218585413503481810tt55tt62

-9218585413503481810tt55
type: Position
type: ExactPosition
position: 55
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt62
type: Position
type: ExactPosition
position: 62
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt3
type: Position
type: ExactPosition
position: 3
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt15
type: Position
type: ExactPosition
position: 15
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt19
type: Position
type: ExactPosition
position: 19
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt25
type: Position
type: ExactPosition
position: 25
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt31
type: Position
type: ExactPosition
position: 31
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt34
type: Position
type: ExactPosition
position: 34
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt41
type: Position
type: ExactPosition
position: 41
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt43
type: Position
type: ExactPosition
position: 43
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt44
type: Position
type: ExactPosition
position: 44
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt52
type: Position
type: ExactPosition
position: 52
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt64
type: Position
type: ExactPosition
position: 64
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt67
type: Position
type: ExactPosition
position: 67
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt70
type: Position
type: ExactPosition
position: 70
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt77
type: Position
type: ExactPosition
position: 77
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt82
type: Position
type: ExactPosition
position: 82
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt85
type: Position
type: ExactPosition
position: 85
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt92
type: Position
type: ExactPosition
position: 92
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt99
type: Position
type: ExactPosition
position: 99
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt102
type: Position
type: ExactPosition
position: 102
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt110
type: Position
type: ExactPosition
position: 110
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt116
type: Position
type: ExactPosition
position: 116
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt119
type: Position
type: ExactPosition
position: 119
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt120
type: Position
type: ExactPosition
position: 120
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt129
type: Position
type: ExactPosition
position: 129
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt130
type: Position
type: ExactPosition
position: 130
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

-9218585413503481810tt133
type: Position
type: ExactPosition
position: 133
reference: MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI

MSEKIEGIIDDLLNLEENAHGIAIIGKDGKIITQTENWNISNDLDKLNEFLNEKLALGKKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVVICPIPIGGTGALITYVNPRAGPRDVLFNVQEYAKKLTDLI
type: Simple Sequence
modified: 2015-07-22
version: 1
mass: 14701

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-EAD340122A69BB28D31B0FEE2EFE1E6E
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-D60EC1842F317BD9516651888BE9D9D7
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-BE18E8E30B16EC0FDB7C2C67E07E90A7
manual: true
evidence: ECO_0007744
source: 5YED

http://purl.uniprot.org/uniprot/A0A0F8V8L2#attribution-2D886423A68474D83B6BDA4585BD3663
manual: true
evidence: ECO_0007744
source: 5YEE

A0A0F8XMN8
type: Protein
reviewed: true
created: 2020-08-12
modified: 2023-02-22
version: 23
mnemonic: PROF2_LOKSG
citation: http://purl.uniprot.org/citations/25945739
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIPECE7152828386D4A
organism: http://purl.uniprot.org/taxonomy/1538547
annotation: SIP6400C5961DECCF42
annotation: SIPADB654D12AFD34CD
annotation: SIPABE6E5EA773225B2
annotation: SIP9F96FEEB07895E9B
annotation: SIPAC48205F0905590A
annotation: SIPA5BCD6F7BD09CA9A
annotation: PRO_0000450550
annotation: SIP2388F9CFA954463C
annotation: SIP25A87488DC7224CF
annotation: SIP0443C5C91E8A1C94
annotation: SIP7841A93BA9788C7A
annotation: SIP284CB3A434B4AFE6
annotation: SIP7760B923C823BD9F
annotation: SIPB2C94F7D0262E1D9
annotation: SIP6DB3CD59E30DE8A4
annotation: SIP3CF1FF38C43742D6
annotation: SIPA6DE1632ECDAC0F7
annotation: SIP24062A4180433443
annotation: SIP1E89ABABAF8D6EE6
annotation: SIP102F53E8A36C3E1E
annotation: SIP6649C34DFBC830A4
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/9
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
classified with: GO_0003779
sequence: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI
proteome: Unassembled WGS sequence

A0A0F8XMN8-citation-25945739
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

GC14_75
type: Strain

A0A0F8XMN8-citation-30283132
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH RABBIT ACTIN
scope: FUNCTION
scope: ACTIVITY REGULATION
scope: SUBCELLULAR LOCATION
scope: DOMAIN

5ZZB
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.30
chain sequence mapping: PDB 5ZZB tt1tt134

PDB 5ZZB tt1tt134
chain: A/C=1-134

SIPECE7152828386D4A
type: Structured Name
full name: Loki profilin-2

http://purl.uniprot.org/uniprot/A0A0F8XMN8#gene-MD57FB13E1F8CB906D0F1F12694F09B87CD
type: Gene
orf name: Lokiarch_27400

SIP6400C5961DECCF42
type: Function Annotation
comment: Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.

SIPADB654D12AFD34CD
type: Activity Regulation Annotation
comment: Inhibition of rabbit actin polymerization is reduced by phosphatidylinositol-(4,5)-P2(1,2-dipalmitoyl), a soluble form of the phospholipid phosphatidylinositol, suggesting an unknown lipid might regulate actin-profilin interaction in vivo.

SIP9F96FEEB07895E9B
type: Domain Annotation
comment: The Loki loop (specific to some members) becomes ordered on binding to rabbit actin.

SIPAC48205F0905590A
type: Annotation
comment: It is not clear if Loki profilins 1, 2 and 3 are from the same strain.

SIPA5BCD6F7BD09CA9A
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450550
type: Chain Annotation
comment: Loki profilin-2
mass: 14622
range: -9218585413347205074tt1tt134

-9218585413347205074tt1
type: Position
type: ExactPosition
position: 1
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt134
type: Position
type: ExactPosition
position: 134
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

SIP2388F9CFA954463C
type: Region Annotation
comment: Loki loop
range: -9218585413347205074tt55tt62

-9218585413347205074tt55
type: Position
type: ExactPosition
position: 55
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt62
type: Position
type: ExactPosition
position: 62
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt3
type: Position
type: ExactPosition
position: 3
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt15
type: Position
type: ExactPosition
position: 15
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt19
type: Position
type: ExactPosition
position: 19
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt25
type: Position
type: ExactPosition
position: 25
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt29
type: Position
type: ExactPosition
position: 29
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt34
type: Position
type: ExactPosition
position: 34
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt41
type: Position
type: ExactPosition
position: 41
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt43
type: Position
type: ExactPosition
position: 43
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt44
type: Position
type: ExactPosition
position: 44
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt51
type: Position
type: ExactPosition
position: 51
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt64
type: Position
type: ExactPosition
position: 64
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt67
type: Position
type: ExactPosition
position: 67
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt70
type: Position
type: ExactPosition
position: 70
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt77
type: Position
type: ExactPosition
position: 77
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt82
type: Position
type: ExactPosition
position: 82
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt85
type: Position
type: ExactPosition
position: 85
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt92
type: Position
type: ExactPosition
position: 92
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt99
type: Position
type: ExactPosition
position: 99
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt102
type: Position
type: ExactPosition
position: 102
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt110
type: Position
type: ExactPosition
position: 110
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt116
type: Position
type: ExactPosition
position: 116
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt119
type: Position
type: ExactPosition
position: 119
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt120
type: Position
type: ExactPosition
position: 120
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt129
type: Position
type: ExactPosition
position: 129
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt130
type: Position
type: ExactPosition
position: 130
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

-9218585413347205074tt133
type: Position
type: ExactPosition
position: 133
reference: MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI

MSEKIEGIIDDLLNVEENADAIAIIGKDGQIVTQTENWNVSNDLEIINELLNEKLALGEKGITSLSIQGIKYMIVENTEERKIGTNITGKGHVLICPIPIGGPGALIAYVNPRAGPRDLLFNVQEYAKKLINLI
type: Simple Sequence
modified: 2015-07-22
version: 1
mass: 14622

http://purl.uniprot.org/uniprot/A0A0F8XMN8#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8XMN8#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8XMN8#attribution-EAD340122A69BB28D31B0FEE2EFE1E6E
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A0F8XMN8#attribution-EB79BE897605996F4BE662EA565FD36C
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8XMN8#attribution-8BC5A8B208D2BB516FBC5FB6C03F40F6
manual: true
evidence: ECO_0007744
source: 5ZZB

A0A0F8VPX6
type: Protein
reviewed: true
created: 2020-08-12
modified: 2023-02-22
version: 20
mnemonic: PROF3_LOKSG
citation: http://purl.uniprot.org/citations/25945739
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIP6FDB5C374BD604E3
organism: http://purl.uniprot.org/taxonomy/1538547
annotation: SIPABC286A293B8A8D4
annotation: SIP1E0E1EBB3384C65A
annotation: SIP27F137AEE80B447E
annotation: SIP1866A34447AB5DF6
annotation: PRO_0000450551
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/9
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
classified with: GO_0003779
sequence: MEEQKFHSLVKALNEHEGIEEVFLLNKDGSIIYKSGEFSLTDDEAKSILSAWKEKEPSLSFQNFRFAILKNDDLQLAAKNIGKGKGNIVGSITREGDYLIAHTRDEALILLEWSIFINKVAWS
proteome: Unassembled WGS sequence

A0A0F8VPX6-citation-25945739
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

GC14_75
type: Strain

A0A0F8VPX6-citation-30283132
type: Citation Statement
scope: FUNCTION
scope: SUBCELLULAR LOCATION

SIP6FDB5C374BD604E3
type: Structured Name
full name: Loki profilin-3

http://purl.uniprot.org/uniprot/A0A0F8VPX6#gene-MD53153105CCFE96C4055CE4D77B65BB185
type: Gene
orf name: Lokiarch_01510

SIPABC286A293B8A8D4
type: Function Annotation
comment: Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.

SIP27F137AEE80B447E
type: Annotation
comment: It is not clear if Loki profilins 1, 2 and 3 are from the same strain.

SIP1866A34447AB5DF6
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450551
type: Chain Annotation
comment: Loki profilin-3
mass: 13943
range: -9218585413478115282tt1tt123

-9218585413478115282tt1
type: Position
type: ExactPosition
position: 1
reference: MEEQKFHSLVKALNEHEGIEEVFLLNKDGSIIYKSGEFSLTDDEAKSILSAWKEKEPSLSFQNFRFAILKNDDLQLAAKNIGKGKGNIVGSITREGDYLIAHTRDEALILLEWSIFINKVAWS

-9218585413478115282tt123
type: Position
type: ExactPosition
position: 123
reference: MEEQKFHSLVKALNEHEGIEEVFLLNKDGSIIYKSGEFSLTDDEAKSILSAWKEKEPSLSFQNFRFAILKNDDLQLAAKNIGKGKGNIVGSITREGDYLIAHTRDEALILLEWSIFINKVAWS

MEEQKFHSLVKALNEHEGIEEVFLLNKDGSIIYKSGEFSLTDDEAKSILSAWKEKEPSLSFQNFRFAILKNDDLQLAAKNIGKGKGNIVGSITREGDYLIAHTRDEALILLEWSIFINKVAWS
type: Simple Sequence
modified: 2015-07-22
version: 1
mass: 13943

http://purl.uniprot.org/uniprot/A0A0F8VPX6#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8VPX6#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A0F8VPX6#attribution-EAD340122A69BB28D31B0FEE2EFE1E6E
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A0F8VPX6#attribution-D60EC1842F317BD9516651888BE9D9D7
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132

A0A1Q9P359
type: Protein
reviewed: true
created: 2020-08-12
modified: 2022-12-14
version: 12
mnemonic: PROF_HEILC
citation: http://purl.uniprot.org/citations/28077874
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIP7C90C74CE64AFD09
organism: http://purl.uniprot.org/taxonomy/1841597
annotation: SIP22168EA9D860823D
annotation: SIP5C39790C1225105B
annotation: SIP0DDEF5F106882456
annotation: PRO_0000450552
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/9
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
classified with: GO_0003779
sequence: MSFNDKAAEAVASGDIGVGWLLSDQCEVFWNVGSWEGANPCEILTEWKKSAMTPITIAGLKFTIIGKTPERLVSTNIGGQGHIVGAKCTNYPGYLVCWCPATVGPNIAYSVIQKLADLVKA
proteome: Unassembled WGS sequence

A0A1Q9P359-citation-28077874
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

LC_2
type: Strain

A0A1Q9P359-citation-30283132
type: Citation Statement
scope: FUNCTION
scope: SUBCELLULAR LOCATION

SIP7C90C74CE64AFD09
type: Structured Name
full name: Heimdall profilin

http://purl.uniprot.org/uniprot/A0A1Q9P359#gene-MD5036D3EE280C1C35AD4A06DD4026689F7
type: Gene
orf name: HeimC2_04030

SIP22168EA9D860823D
type: Function Annotation
comment: Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.

SIP0DDEF5F106882456
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450552
type: Chain Annotation
comment: Heimdall profilin
mass: 12905
range: -9218580255656025042tt1tt121

-9218580255656025042tt1
type: Position
type: ExactPosition
position: 1
reference: MSFNDKAAEAVASGDIGVGWLLSDQCEVFWNVGSWEGANPCEILTEWKKSAMTPITIAGLKFTIIGKTPERLVSTNIGGQGHIVGAKCTNYPGYLVCWCPATVGPNIAYSVIQKLADLVKA

-9218580255656025042tt121
type: Position
type: ExactPosition
position: 121
reference: MSFNDKAAEAVASGDIGVGWLLSDQCEVFWNVGSWEGANPCEILTEWKKSAMTPITIAGLKFTIIGKTPERLVSTNIGGQGHIVGAKCTNYPGYLVCWCPATVGPNIAYSVIQKLADLVKA

MSFNDKAAEAVASGDIGVGWLLSDQCEVFWNVGSWEGANPCEILTEWKKSAMTPITIAGLKFTIIGKTPERLVSTNIGGQGHIVGAKCTNYPGYLVCWCPATVGPNIAYSVIQKLADLVKA
type: Simple Sequence
modified: 2017-04-12
version: 1
mass: 12905

http://purl.uniprot.org/uniprot/A0A1Q9P359#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9P359#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9P359#attribution-4150B6360E9C5BE69D9B6624F135FB53
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A1Q9P359#attribution-D60EC1842F317BD9516651888BE9D9D7
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132

A0A1Q9N7W7
type: Protein
reviewed: true
created: 2020-08-12
modified: 2023-02-22
version: 16
mnemonic: PROF_ODILC
citation: http://purl.uniprot.org/citations/28077874
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIPB06C9B7BEC47BFAF
organism: http://purl.uniprot.org/taxonomy/1841599
annotation: SIP8E2AB371C0734832
annotation: SIP5D2F163E26C07A85
annotation: SIPAD10D0E60D34FD2C
annotation: SIPF2409FF7991A1F48
annotation: PRO_0000450553
annotation: SIP263E7CE3608C81DD
annotation: SIP99304C3A3BA02B57
annotation: SIP0846666DDF6A0688
annotation: SIPE5D82AD1AE270712
annotation: SIP3A51A0F84909E759
annotation: SIPF20F32DBEB367EA2
annotation: SIPC5F2C76BD255F46E
annotation: SIP4D6FEBD663C934A7
annotation: SIP900AAD0B9A6EBDC6
annotation: SIP929925416415BB6B
annotation: SIP105791C0C227998D
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/9
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
classified with: GO_0003779
sequence: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL
proteome: Unassembled WGS sequence

A0A1Q9N7W7-citation-28077874
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

LCB_4
type: Strain

A0A1Q9N7W7-citation-30283132
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (1.53 ANGSTROMS) IN COMPLEX WITH RABBIT ACTIN
scope: FUNCTION
scope: ACTIVITY REGULATION
scope: SUBCELLULAR LOCATION

5ZZA
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.53
chain sequence mapping: PDB 5ZZA tt1tt119

PDB 5ZZA tt1tt119
chain: P=1-119

SIPB06C9B7BEC47BFAF
type: Structured Name
full name: Odin profilin

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#gene-MD5D4E855DAE05832EA4862539A60D29DFD
type: Gene
orf name: OdinLCB4_14170

SIP8E2AB371C0734832
type: Function Annotation
comment: Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.

SIP5D2F163E26C07A85
type: Activity Regulation Annotation
comment: Inhibition of rabbit actin polymerization is reduced by phosphatidylinositol-(4,5)-P2(1,2-dipalmitoyl), a soluble form of the phospholipid phosphatidylinositol, suggesting an unknown lipid might regulate actin-profilin interaction in vivo.

SIPF2409FF7991A1F48
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450553
type: Chain Annotation
comment: Odin profilin
mass: 12648
range: -9218580255785493458tt1tt119

-9218580255785493458tt1
type: Position
type: ExactPosition
position: 1
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt119
type: Position
type: ExactPosition
position: 119
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt3
type: Position
type: ExactPosition
position: 3
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt9
type: Position
type: ExactPosition
position: 9
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt15
type: Position
type: ExactPosition
position: 15
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt22
type: Position
type: ExactPosition
position: 22
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt27
type: Position
type: ExactPosition
position: 27
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt30
type: Position
type: ExactPosition
position: 30
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt38
type: Position
type: ExactPosition
position: 38
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt47
type: Position
type: ExactPosition
position: 47
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt50
type: Position
type: ExactPosition
position: 50
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt54
type: Position
type: ExactPosition
position: 54
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt57
type: Position
type: ExactPosition
position: 57
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt73
type: Position
type: ExactPosition
position: 73
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt74
type: Position
type: ExactPosition
position: 74
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt77
type: Position
type: ExactPosition
position: 77
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt78
type: Position
type: ExactPosition
position: 78
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt85
type: Position
type: ExactPosition
position: 85
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt86
type: Position
type: ExactPosition
position: 86
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt88
type: Position
type: ExactPosition
position: 88
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt89
type: Position
type: ExactPosition
position: 89
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt95
type: Position
type: ExactPosition
position: 95
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt101
type: Position
type: ExactPosition
position: 101
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

-9218580255785493458tt116
type: Position
type: ExactPosition
position: 116
reference: MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL

MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREPSIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGDARTAYIQIDKTARQLSKIL
type: Simple Sequence
modified: 2017-04-12
version: 1
mass: 12648

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#attribution-4150B6360E9C5BE69D9B6624F135FB53
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#attribution-D60EC1842F317BD9516651888BE9D9D7
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9N7W7#attribution-31DD4D9B4B4A0AA6BC92F4063B0B1B08
manual: true
evidence: ECO_0007744
source: 5ZZA

A0A1Q9PA05
type: Protein
reviewed: true
created: 2020-08-12
modified: 2023-02-22
version: 14
mnemonic: PROF_THOAA
citation: http://purl.uniprot.org/citations/28077874
citation: http://purl.uniprot.org/citations/30283132
recommended name: SIP0E107283EE215428
organism: http://purl.uniprot.org/taxonomy/1837170
annotation: SIPDE32900A8AA59A1D
annotation: SIPD6841AB6DCB4A9B7
annotation: SIP6B190FD900AF98D6
annotation: PRO_0000450554
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/206
classified with: GO_0005737
classified with: GO_0005856
sequence: MSDPVMDAYTQAYNSSGNMVQAFGVISESGQVLWQSNNWDLTADASTLMSAVKSRASSVIQNQVKYSTMRSTPESLVARNVQGSGILILTKIDTTSDRWVVAWADAQAQPDGVYVDVDRAAKTLRGKI
proteome: Unassembled WGS sequence

A0A1Q9PA05-citation-28077874
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

AB_25
type: Strain

A0A1Q9PA05-citation-30283132
type: Citation Statement
scope: POSSIBLE LACK OF FUNCTION AS A PROFILIN

SIP0E107283EE215428
type: Structured Name
full name: Thor profilin

http://purl.uniprot.org/uniprot/A0A1Q9PA05#gene-MD5D396F2BAE7606D55EA1C2F189BCFF560
type: Gene
orf name: ThorAB25_04690

SIPDE32900A8AA59A1D
type: Function Annotation
comment: Has no profilin activity against rabbit actin.

SIP6B190FD900AF98D6
type: Similarity Annotation
comment: Belongs to the Asgard profilin family.

PRO_0000450554
type: Chain Annotation
comment: Thor profilin
mass: 13892
range: -9218580255641430994tt1tt128

-9218580255641430994tt1
type: Position
type: ExactPosition
position: 1
reference: MSDPVMDAYTQAYNSSGNMVQAFGVISESGQVLWQSNNWDLTADASTLMSAVKSRASSVIQNQVKYSTMRSTPESLVARNVQGSGILILTKIDTTSDRWVVAWADAQAQPDGVYVDVDRAAKTLRGKI

-9218580255641430994tt128
type: Position
type: ExactPosition
position: 128
reference: MSDPVMDAYTQAYNSSGNMVQAFGVISESGQVLWQSNNWDLTADASTLMSAVKSRASSVIQNQVKYSTMRSTPESLVARNVQGSGILILTKIDTTSDRWVVAWADAQAQPDGVYVDVDRAAKTLRGKI

MSDPVMDAYTQAYNSSGNMVQAFGVISESGQVLWQSNNWDLTADASTLMSAVKSRASSVIQNQVKYSTMRSTPESLVARNVQGSGILILTKIDTTSDRWVVAWADAQAQPDGVYVDVDRAAKTLRGKI
type: Simple Sequence
modified: 2017-04-12
version: 1
mass: 13892

http://purl.uniprot.org/uniprot/A0A1Q9PA05#attribution-D8097BA693BDAE03DF435172211A63F9
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9PA05#attribution-96337D8B64B39080D3821EF7EBFF1A1E
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/30283132

http://purl.uniprot.org/uniprot/A0A1Q9PA05#attribution-4150B6360E9C5BE69D9B6624F135FB53
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/A0A1Q9PA05#attribution-D60EC1842F317BD9516651888BE9D9D7
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/30283132