Q9HKL4
type: Protein
reviewed: true
created: 2007-05-01
modified: 2023-02-22
version: 81
mnemonic: ACTH_THEAC
citation: http://purl.uniprot.org/citations/11029001
citation: http://purl.uniprot.org/citations/17189356
citation: http://purl.uniprot.org/citations/16500678
recommended name: SIP5250F17171097669
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP3D01274CAF0E2985
annotation: SIP9ED23D3238203EE5
annotation: SIPA6FC425699537E48
annotation: SIP678063FF60D7574D
annotation: SIPC685ED44C771A368
annotation: SIPA59F403FDA3C688B
annotation: PRO_0000285695
annotation: SIP151399C7B7B08491
annotation: SIPCF9A62EE1BCB972C
annotation: SIP2FB2C5FE9D2BF071
annotation: SIPBFB094D484158CA9
annotation: SIPF200BABD45B7F40F
annotation: SIP470F0E6D05C25733
annotation: SIP7599E1264FF30B9F
annotation: SIP1ADF0F11E3B20B26
annotation: SIPFD0C9C8ADCE9AE70
annotation: SIPC69CF182A35BB003
annotation: SIP87CF86BF9A55FA4E
annotation: SIP9F8D34DC64DAD4F9
annotation: SIPA7EF1EFF7481F723
annotation: SIPED59D5BDDF8CD8E4
annotation: SIPA09AD64A76911FDF
annotation: SIP624EA02BE7516849
annotation: SIPDB47A0B8615C6BE9
annotation: SIP259AC9DFA50DCD13
annotation: SIP223341313A0080CC
annotation: SIP383A62BC1963BE09
annotation: SIP01076E1DC042621E
annotation: SIPDF05BCEB2BA8DBD9
annotation: SIPE288B19304476615
annotation: SIPD16194180FF7EDE3
annotation: SIP4D72459CCAE1F66E
annotation: SIP26B8B90E33768E01
annotation: SIPFA5FA1E2E7F3228C
annotation: SIP4942D2369270DDF1
annotation: SIPEDD2D4F19314EA15
annotation: SIPDE2D241707B70EF3
annotation: SIPB6D9E9BB0304B26B
annotation: SIP3DA263FB5FFEA39C
annotation: SIPE6CE436C76C7FE11
annotation: SIP46EE21E643A7BE3C
annotation: SIPEC39A842E8AF6A64
annotation: SIP46F841D153CCA465
annotation: SIP276EBF71EC9906D3
annotation: SIP68FE57EAD5381B53
annotation: SIP43C7BE918F2FBA09
annotation: SIP338E90F23BA98A06
annotation: SIP347A37687AD0B341
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
sequence: Q9HKL4-1
proteome: Chromosome

Q9HKL4-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

Q9HKL4-citation-17189356
type: Citation Statement
scope: FUNCTION
scope: BIOPHYSICOCHEMICAL PROPERTIES

Q9HKL4-citation-16500678
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH ADP
scope: FUNCTION
scope: ATPASE ACTIVITY
scope: KINETIC PARAMETERS

2FSJ
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.90
chain sequence mapping: PDB 2FSJ tt1tt326

PDB 2FSJ tt1tt326
chain: A=1-326

2FSK
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.10
chain sequence mapping: PDB 2FSK tt1tt326

PDB 2FSK tt1tt326
chain: A/B=1-326

2FSN
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.90
chain sequence mapping: PDB 2FSN tt1tt326

PDB 2FSN tt1tt326
chain: A/B=1-326

arCOG03062
type: Resource
database: eggNOG
comment: Archaea

cd10227
type: Resource
database: CDD
comment: ParM_like
signature sequence match: CDD cd10227 match 1

IPR040607
type: Resource
database: InterPro
comment: ALP_N

IPR043129
type: Resource
database: InterPro
comment: ATPase_NBD

IPR042051
type: Resource
database: InterPro
comment: ParM-like

PF17989
type: Resource
database: Pfam
comment: ALP_N
signature sequence match: Pfam PF17989 match 1

SSF53067
type: Resource
database: SUPFAM
comment: Actin-like ATPase domain
signature sequence match: SUPFAM SSF53067 match 1
signature sequence match: SUPFAM SSF53067 match 2

SIP5250F17171097669
type: Structured Name
full name: Archaeal actin homolog

http://purl.uniprot.org/uniprot/Q9HKL4#gene-MD5EF771E397E88895F53EBDCEFED624F7D
type: Gene
locus name: Ta0583

SIP3D01274CAF0E2985
type: Function Annotation
comment: Polymerizes into bundles of filaments, forming a helix with a filament width of 5.5 nm and an axial repeating unit of 5.5 nm. Polymerization of Ta0583 requires NTP and is optimal with ATP, but GTP, UTP, CTP, and even the deoxy form of NTP can also support the polymerization reaction. Nucleoside diphosphate or AMP-PNP does not support polymerization.

SIP9ED23D3238203EE5
type: Kinetics Annotation
measured affinity: 289 uM for ATP (when assaying the ATPase activity)

SIPA6FC425699537E48
type: PH Dependence Annotation
comment: Optimum pH is 4.5-5.5 for the polymerization reaction.

SIP678063FF60D7574D
type: Temperature Dependence Annotation
comment: Optimum temperature is 50-56 degrees Celsius for the polymerization reaction.

SIPC685ED44C771A368
type: Annotation
comment: Mg(2+) is required for polymerization. 4 mM MgCl(2) is sufficient to enhance the polymerization; however, higher concentrations of MgCl(2) suppresses polymerization. Polymerization is also suppressed by addition of NaCl, KCl or CaCl(2), with half suppression by about 100 mM, 10 mM and 18 mM, respectively.

SIPA59F403FDA3C688B
type: Similarity Annotation
comment: Belongs to the thermophilic archaeal actin family.

PRO_0000285695
type: Chain Annotation
comment: Archaeal actin homolog
mass: 34880
range: 22862455777276974tt1tt326

22862455777276974tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKL4-1

22862455777276974tt326
type: Position
type: ExactPosition
position: 326
reference: Q9HKL4-1

22862455777276974tt10
type: Position
type: ExactPosition
position: 10
reference: Q9HKL4-1

22862455777276974tt14
type: Position
type: ExactPosition
position: 14
reference: Q9HKL4-1

22862455777276974tt179
type: Position
type: ExactPosition
position: 179
reference: Q9HKL4-1

22862455777276974tt231
type: Position
type: ExactPosition
position: 231
reference: Q9HKL4-1

22862455777276974tt285
type: Position
type: ExactPosition
position: 285
reference: Q9HKL4-1

22862455777276974tt288
type: Position
type: ExactPosition
position: 288
reference: Q9HKL4-1

22862455777276974tt311
type: Position
type: ExactPosition
position: 311
reference: Q9HKL4-1

22862455777276974tt2
type: Position
type: ExactPosition
position: 2
reference: Q9HKL4-1

22862455777276974tt8
type: Position
type: ExactPosition
position: 8
reference: Q9HKL4-1

22862455777276974tt16
type: Position
type: ExactPosition
position: 16
reference: Q9HKL4-1

22862455777276974tt18
type: Position
type: ExactPosition
position: 18
reference: Q9HKL4-1

22862455777276974tt20
type: Position
type: ExactPosition
position: 20
reference: Q9HKL4-1

22862455777276974tt22
type: Position
type: ExactPosition
position: 22
reference: Q9HKL4-1

22862455777276974tt27
type: Position
type: ExactPosition
position: 27
reference: Q9HKL4-1

22862455777276974tt29
type: Position
type: ExactPosition
position: 29
reference: Q9HKL4-1

22862455777276974tt32
type: Position
type: ExactPosition
position: 32
reference: Q9HKL4-1

22862455777276974tt40
type: Position
type: ExactPosition
position: 40
reference: Q9HKL4-1

22862455777276974tt42
type: Position
type: ExactPosition
position: 42
reference: Q9HKL4-1

22862455777276974tt46
type: Position
type: ExactPosition
position: 46
reference: Q9HKL4-1

22862455777276974tt49
type: Position
type: ExactPosition
position: 49
reference: Q9HKL4-1

22862455777276974tt52
type: Position
type: ExactPosition
position: 52
reference: Q9HKL4-1

22862455777276974tt57
type: Position
type: ExactPosition
position: 57
reference: Q9HKL4-1

22862455777276974tt58
type: Position
type: ExactPosition
position: 58
reference: Q9HKL4-1

22862455777276974tt60
type: Position
type: ExactPosition
position: 60
reference: Q9HKL4-1

22862455777276974tt63
type: Position
type: ExactPosition
position: 63
reference: Q9HKL4-1

22862455777276974tt65
type: Position
type: ExactPosition
position: 65
reference: Q9HKL4-1

22862455777276974tt75
type: Position
type: ExactPosition
position: 75
reference: Q9HKL4-1

22862455777276974tt77
type: Position
type: ExactPosition
position: 77
reference: Q9HKL4-1

22862455777276974tt78
type: Position
type: ExactPosition
position: 78
reference: Q9HKL4-1

22862455777276974tt80
type: Position
type: ExactPosition
position: 80
reference: Q9HKL4-1

22862455777276974tt81
type: Position
type: ExactPosition
position: 81
reference: Q9HKL4-1

22862455777276974tt91
type: Position
type: ExactPosition
position: 91
reference: Q9HKL4-1

22862455777276974tt100
type: Position
type: ExactPosition
position: 100
reference: Q9HKL4-1

22862455777276974tt108
type: Position
type: ExactPosition
position: 108
reference: Q9HKL4-1

22862455777276974tt110
type: Position
type: ExactPosition
position: 110
reference: Q9HKL4-1

22862455777276974tt112
type: Position
type: ExactPosition
position: 112
reference: Q9HKL4-1

22862455777276974tt113
type: Position
type: ExactPosition
position: 113
reference: Q9HKL4-1

22862455777276974tt124
type: Position
type: ExactPosition
position: 124
reference: Q9HKL4-1

22862455777276974tt127
type: Position
type: ExactPosition
position: 127
reference: Q9HKL4-1

22862455777276974tt132
type: Position
type: ExactPosition
position: 132
reference: Q9HKL4-1

22862455777276974tt134
type: Position
type: ExactPosition
position: 134
reference: Q9HKL4-1

22862455777276974tt136
type: Position
type: ExactPosition
position: 136
reference: Q9HKL4-1

22862455777276974tt138
type: Position
type: ExactPosition
position: 138
reference: Q9HKL4-1

22862455777276974tt150
type: Position
type: ExactPosition
position: 150
reference: Q9HKL4-1

22862455777276974tt153
type: Position
type: ExactPosition
position: 153
reference: Q9HKL4-1

22862455777276974tt161
type: Position
type: ExactPosition
position: 161
reference: Q9HKL4-1

22862455777276974tt169
type: Position
type: ExactPosition
position: 169
reference: Q9HKL4-1

22862455777276974tt177
type: Position
type: ExactPosition
position: 177
reference: Q9HKL4-1

22862455777276974tt182
type: Position
type: ExactPosition
position: 182
reference: Q9HKL4-1

22862455777276974tt188
type: Position
type: ExactPosition
position: 188
reference: Q9HKL4-1

22862455777276974tt189
type: Position
type: ExactPosition
position: 189
reference: Q9HKL4-1

22862455777276974tt191
type: Position
type: ExactPosition
position: 191
reference: Q9HKL4-1

22862455777276974tt196
type: Position
type: ExactPosition
position: 196
reference: Q9HKL4-1

22862455777276974tt198
type: Position
type: ExactPosition
position: 198
reference: Q9HKL4-1

22862455777276974tt200
type: Position
type: ExactPosition
position: 200
reference: Q9HKL4-1

22862455777276974tt203
type: Position
type: ExactPosition
position: 203
reference: Q9HKL4-1

22862455777276974tt206
type: Position
type: ExactPosition
position: 206
reference: Q9HKL4-1

22862455777276974tt221
type: Position
type: ExactPosition
position: 221
reference: Q9HKL4-1

22862455777276974tt227
type: Position
type: ExactPosition
position: 227
reference: Q9HKL4-1

22862455777276974tt233
type: Position
type: ExactPosition
position: 233
reference: Q9HKL4-1

22862455777276974tt238
type: Position
type: ExactPosition
position: 238
reference: Q9HKL4-1

22862455777276974tt240
type: Position
type: ExactPosition
position: 240
reference: Q9HKL4-1

22862455777276974tt243
type: Position
type: ExactPosition
position: 243
reference: Q9HKL4-1

22862455777276974tt245
type: Position
type: ExactPosition
position: 245
reference: Q9HKL4-1

22862455777276974tt248
type: Position
type: ExactPosition
position: 248
reference: Q9HKL4-1

22862455777276974tt270
type: Position
type: ExactPosition
position: 270
reference: Q9HKL4-1

22862455777276974tt271
type: Position
type: ExactPosition
position: 271
reference: Q9HKL4-1

22862455777276974tt276
type: Position
type: ExactPosition
position: 276
reference: Q9HKL4-1

22862455777276974tt277
type: Position
type: ExactPosition
position: 277
reference: Q9HKL4-1

22862455777276974tt284
type: Position
type: ExactPosition
position: 284
reference: Q9HKL4-1

22862455777276974tt287
type: Position
type: ExactPosition
position: 287
reference: Q9HKL4-1

22862455777276974tt290
type: Position
type: ExactPosition
position: 290
reference: Q9HKL4-1

22862455777276974tt291
type: Position
type: ExactPosition
position: 291
reference: Q9HKL4-1

22862455777276974tt297
type: Position
type: ExactPosition
position: 297
reference: Q9HKL4-1

22862455777276974tt307
type: Position
type: ExactPosition
position: 307
reference: Q9HKL4-1

22862455777276974tt312
type: Position
type: ExactPosition
position: 312
reference: Q9HKL4-1

22862455777276974tt313
type: Position
type: ExactPosition
position: 313
reference: Q9HKL4-1

22862455777276974tt323
type: Position
type: ExactPosition
position: 323
reference: Q9HKL4-1

Q9HKL4-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 34880
value: MVVVGLDVGYGDTKVIGVDGKRIIFPSRWAVTETESWGIGGKIPVLSTDGGQTKFIYGKYASGNNIRVPQGDGRLASKEAFPLIAAALWESGIHNDGSPVDLVIGSGTPLGTFDLEVKAAKEALENKVLTVTGPEGEVRQFNITRLIMRPQGVGAALYLLNQGIIEQQPGYGVVIDVGSRTTDVLTINLMDMEPVVELSFSLQIGVGDAISALSRKIAKETGFVVPFDLAQEALSHPVMFRQKQVGGPEVSGPILEDLANRIIENIRLNLRGEVDRVTSLIPVGGGSNLIGDRFEEIAPGTLVKIKPEDLQFANALGYRDAAERSM

http://purl.uniprot.org/uniprot/Q9HKL4#attribution-B4417662F1D8A26EBFCCA05BC3DBE5D6
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/16500678

http://purl.uniprot.org/uniprot/Q9HKL4#attribution-2C15ED853133388E76274E6571A34054
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/17189356

http://purl.uniprot.org/uniprot/Q9HKL4#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q97B19
type: Protein
reviewed: true
created: 2007-05-01
modified: 2023-02-22
version: 79
mnemonic: ACTH_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP5250F17171097669
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP3D722470587A9EED
annotation: SIP95C600C96931A7EC
annotation: PRO_0000285696
annotation: SIPAB7190CCACF2613D
annotation: SIPF0845354AF8BBB8D
annotation: SIP40E3E0F7C2C38731
annotation: SIPEB03CB658A7F4415
annotation: SIPA1F36F1497CE20CB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: GO_0005524
sequence: Q97B19-1
proteome: Chromosome

Q97B19-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP5250F17171097669
type: Structured Name
full name: Archaeal actin homolog

http://purl.uniprot.org/uniprot/Q97B19#gene-MD50DFC87121B4BAEBCB19C103E609C481F
type: Gene
locus name: TV0640
orf name: TVG0633900

SIP3D722470587A9EED
type: Function Annotation
comment: Polymerizes into bundles of filaments. Polymerization requires NTP and is optimal with ATP, but GTP, UTP, CTP, and even the deoxy form of NTP can also support the polymerization reaction (By similarity).

SIP95C600C96931A7EC
type: Similarity Annotation
comment: Belongs to the thermophilic archaeal actin family.

PRO_0000285696
type: Chain Annotation
comment: Archaeal actin homolog
mass: 34970
range: 22862382610069806tt1tt326

22862382610069806tt1
type: Position
type: ExactPosition
position: 1
reference: Q97B19-1

22862382610069806tt326
type: Position
type: ExactPosition
position: 326
reference: Q97B19-1

22862382610069806tt10
type: Position
type: ExactPosition
position: 10
reference: Q97B19-1

22862382610069806tt14
type: Position
type: ExactPosition
position: 14
reference: Q97B19-1

22862382610069806tt179
type: Position
type: ExactPosition
position: 179
reference: Q97B19-1

22862382610069806tt231
type: Position
type: ExactPosition
position: 231
reference: Q97B19-1

22862382610069806tt285
type: Position
type: ExactPosition
position: 285
reference: Q97B19-1

22862382610069806tt288
type: Position
type: ExactPosition
position: 288
reference: Q97B19-1

22862382610069806tt311
type: Position
type: ExactPosition
position: 311
reference: Q97B19-1

Q97B19-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 34970
value: MVVIGLDVGYGDTKVIGIDGKRIIFPSRWAVTETESWGIGGKIPVLSTDGGQTKFIYGRYASGNNIRVPQGDGRLASKEAFPLIAAALWESGIHNDGSPVDLVIGSGTPLGTFDLEVKAAKEALENKILTVTGPEGEVRQYNVTRLIMRPQGVGAALYLLNQGIIEQQPGYGVVIDVGSRTTDVLTINLMDMEPVVELSFSLQIGVGDAISNLSRKIAKETGFVVPFDLAQEALSKPVMFRQKQVGGPEVAGPILEDLANRIIENIRLNLRGEVDRITSLIPVGGGANLIGDRFDEIAPGTTVRIKPEDLQFANALGYRDAAERSM

http://purl.uniprot.org/uniprot/Q97B19#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q97B19#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6L2I0
type: Protein
reviewed: true
created: 2008-04-08
modified: 2023-02-22
version: 87
mnemonic: ACYP_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIPA8A85A3B6EB2C5A6
alternative name: SIP1D8FEE61EF0477DE
enzyme: http://purl.uniprot.org/enzyme/3.6.1.7
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP2F709FE5D5AFF591
annotation: SIPEAC1D6507D021970
annotation: PRO_0000326864
annotation: SIP137B904BB7A2A15B
annotation: SIP3B11569B514028AA
annotation: SIP64A0ECFE9D45276B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003998
sequence: MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY
proteome: Chromosome

Q6L2I0-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG01674
type: Resource
database: eggNOG
comment: Archaea

IPR020456
type: Resource
database: InterPro
comment: Acylphosphatase

IPR001792
type: Resource
database: InterPro
comment: Acylphosphatase-like_dom

IPR036046
type: Resource
database: InterPro
comment: Acylphosphatase-like_dom_sf

PTHR47268
type: Resource
database: PANTHER
comment: ACYLPHOSPHATASE
signature sequence match: PANTHER PTHR47268 match 1

PTHR47268:SF4
type: Resource
database: PANTHER
comment: ACYLPHOSPHATASE
signature sequence match: PANTHER PTHR47268:SF4 match 1

PF00708
type: Resource
database: Pfam
comment: Acylphosphatase
signature sequence match: Pfam PF00708 match 1

SSF54975
type: Resource
database: SUPFAM
comment: Acylphosphatase/BLUF domain-like
signature sequence match: SUPFAM SSF54975 match 1

PS51160
type: Resource
database: PROSITE
comment: ACYLPHOSPHATASE_3
signature sequence match: PROSITE PS51160 match 1

SIPA8A85A3B6EB2C5A6
type: Structured Name
full name: Acylphosphatase
ec name: 3.6.1.7

SIP1D8FEE61EF0477DE
type: Structured Name
full name: Acylphosphate phosphohydrolase

acyP
type: Gene
locus name: PTO0237

SIPEAC1D6507D021970
type: Similarity Annotation
comment: Belongs to the acylphosphatase family.

PRO_0000326864
type: Chain Annotation
comment: Acylphosphatase
mass: 9510
range: 22859174002634798tt1tt81

22859174002634798tt1
type: Position
type: ExactPosition
position: 1
reference: MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY

22859174002634798tt81
type: Position
type: ExactPosition
position: 81
reference: MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY

SIP137B904BB7A2A15B
type: Domain Extent Annotation
comment: Acylphosphatase-like
range: 22859174002634798tt1tt81

22859174002634798tt14
type: Position
type: ExactPosition
position: 14
reference: MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY

22859174002634798tt32
type: Position
type: ExactPosition
position: 32
reference: MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY

MYIFHGRVQGIGLRARTYSMAKSLGLSGYIKNRDDGTVEAVFQGDEEKIKRIIEYIKGIAYIEKIDYFDDDVKYNDFQIRY
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 9510

http://purl.uniprot.org/uniprot/Q6L2I0#attribution-98D8AACB6088A1FDF75D73B81D511F37
manual: true
evidence: ECO_0000255
source: PRU00520

http://purl.uniprot.org/uniprot/Q6L2I0#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q97CT1
type: Protein
reviewed: true
created: 2008-04-08
modified: 2023-02-22
version: 97
mnemonic: ACYP_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPA8A85A3B6EB2C5A6
alternative name: SIP1D8FEE61EF0477DE
enzyme: http://purl.uniprot.org/enzyme/3.6.1.7
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP0A1BD91D80775FBE
annotation: SIP3B40FFA7F7185F34
annotation: PRO_0000326873
annotation: SIPE38F6788074D87C4
annotation: SIPB83A24343E1E0D85
annotation: SIP14F2DD6F721A7C3C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: GO_0003998
sequence: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR
proteome: Chromosome

Q97CT1-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

PR00112
type: Resource
database: PRINTS
comment: ACYLPHPHTASE

SIPA8A85A3B6EB2C5A6
type: Structured Name
full name: Acylphosphatase
ec name: 3.6.1.7

SIP1D8FEE61EF0477DE
type: Structured Name
full name: Acylphosphate phosphohydrolase

acyP
type: Gene
locus name: TV0020
orf name: TVG0019502

SIP3B40FFA7F7185F34
type: Similarity Annotation
comment: Belongs to the acylphosphatase family.

PRO_0000326873
type: Chain Annotation
comment: Acylphosphatase
mass: 10532
range: 22862382629138734tt1tt90

22862382629138734tt1
type: Position
type: ExactPosition
position: 1
reference: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR

22862382629138734tt90
type: Position
type: ExactPosition
position: 90
reference: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR

SIPE38F6788074D87C4
type: Domain Extent Annotation
comment: Acylphosphatase-like
range: 22862382629138734tt4tt90

22862382629138734tt4
type: Position
type: ExactPosition
position: 4
reference: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR

22862382629138734tt19
type: Position
type: ExactPosition
position: 19
reference: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR

22862382629138734tt37
type: Position
type: ExactPosition
position: 37
reference: MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR

MLTTRRVRFYGRVQGINFRSNTLVKALELGVKGWIKNLPDGSVEALFSGESEQIEKLISYCVSNMPYAEVKRYDVYIEPYTEFQDFQIKR
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 10532

http://purl.uniprot.org/uniprot/Q97CT1#attribution-98D8AACB6088A1FDF75D73B81D511F37
manual: true
evidence: ECO_0000255
source: PRU00520

http://purl.uniprot.org/uniprot/Q97CT1#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6KZR7
type: Protein
reviewed: true
created: 2008-02-05
modified: 2023-02-22
version: 87
mnemonic: ALBA_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIPFC988FC7BEEA7632
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIPD7676B66654A417B
annotation: SIPB7954E43FA88E8D0
annotation: SIP272A893525920BCB
annotation: SIP9E167485A241BE9A
annotation: SIPC44B8A7707084C28
annotation: PRO_1000065262
annotation: SIP243919AF7B50B0D4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/7
classified with: http://purl.uniprot.org/keywords/158
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/694
classified with: GO_0005694
classified with: GO_0005737
classified with: GO_0003690
classified with: GO_0003723
sequence: MAEENVIFVGKKPTMNYVLAIVTQFNNNSTSRIVIKARGKAISKAVDIAEITRHKFIQDAKYDEIKLDTESLQGEKGESNVSSIEIVLTR
proteome: Chromosome

Q6KZR7-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG01753
type: Resource
database: eggNOG
comment: Archaea

http://purl.uniprot.org/gene3d/3.30.110.20
type: Resource
database: Gene3D
comment: Alba-like domain
signature sequence match: Gene3D 3.30.110.20 match 1

MF_01122
type: Resource
database: HAMAP
comment: AlbA
signature sequence match: HAMAP MF 01122 match 1

IPR036882
type: Resource
database: InterPro
comment: Alba-like_dom_sf

IPR013795
type: Resource
database: InterPro
comment: DNA/RNA-bd_Alba

IPR002775
type: Resource
database: InterPro
comment: DNA/RNA-bd_Alba-like

PF01918
type: Resource
database: Pfam
comment: Alba
signature sequence match: Pfam PF01918 match 1

PIRSF028732
type: Resource
database: PIRSF
comment: Alba
signature sequence match: PIRSF PIRSF028732 match 1

SSF82704
type: Resource
database: SUPFAM
comment: AlbA-like
signature sequence match: SUPFAM SSF82704 match 1

TIGR00285
type: Resource
database: TIGRFAMs
comment: DNA-binding protein Alba
signature sequence match: TIGRFAMs TIGR00285 match 1

SIPFC988FC7BEEA7632
type: Structured Name
full name: DNA/RNA-binding protein Alba

albA
type: Gene
locus name: PTO1200

SIPD7676B66654A417B
type: Function Annotation
comment: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.

SIPB7954E43FA88E8D0
type: Subunit Annotation
comment: Homotetramer.

SIP9E167485A241BE9A
type: PTM Annotation
comment: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.

SIPC44B8A7707084C28
type: Similarity Annotation
comment: Belongs to the histone-like Alba family.

PRO_1000065262
type: Chain Annotation
comment: DNA/RNA-binding protein Alba
mass: 10056
range: 22859170379347758tt1tt90

22859170379347758tt1
type: Position
type: ExactPosition
position: 1
reference: MAEENVIFVGKKPTMNYVLAIVTQFNNNSTSRIVIKARGKAISKAVDIAEITRHKFIQDAKYDEIKLDTESLQGEKGESNVSSIEIVLTR

22859170379347758tt90
type: Position
type: ExactPosition
position: 90
reference: MAEENVIFVGKKPTMNYVLAIVTQFNNNSTSRIVIKARGKAISKAVDIAEITRHKFIQDAKYDEIKLDTESLQGEKGESNVSSIEIVLTR

SIP243919AF7B50B0D4
type: Modified Residue Annotation
comment: N6-acetyllysine
range: 22859170379347758tt12tt12

22859170379347758tt12
type: Position
type: ExactPosition
position: 12
reference: MAEENVIFVGKKPTMNYVLAIVTQFNNNSTSRIVIKARGKAISKAVDIAEITRHKFIQDAKYDEIKLDTESLQGEKGESNVSSIEIVLTR

MAEENVIFVGKKPTMNYVLAIVTQFNNNSTSRIVIKARGKAISKAVDIAEITRHKFIQDAKYDEIKLDTESLQGEKGESNVSSIEIVLTR
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 10056

http://purl.uniprot.org/uniprot/Q6KZR7#attribution-55EE386D4A7E03D47B6D7C2F61E4CAA4
manual: true
evidence: ECO_0000255
source: MF_01122

Q9HJQ5
type: Protein
reviewed: true
created: 2003-09-09
modified: 2023-02-22
version: 93
mnemonic: ALBA_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPFC988FC7BEEA7632
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPC3B4CEF5A3BD015E
annotation: SIP7F65BEC5E82823A6
annotation: SIP395BA5033978019F
annotation: SIP398A2B09FD33120E
annotation: SIP01F1E3E616F8F281
annotation: PRO_0000151716
annotation: SIP1F12E519870B1716
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/7
classified with: http://purl.uniprot.org/keywords/158
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/694
classified with: GO_0005694
classified with: GO_0005737
classified with: GO_0003690
classified with: GO_0003723
sequence: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR
proteome: Chromosome

Q9HJQ5-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

SIPFC988FC7BEEA7632
type: Structured Name
full name: DNA/RNA-binding protein Alba

albA
type: Gene
locus name: Ta0912

SIPC3B4CEF5A3BD015E
type: Function Annotation
comment: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.

SIP7F65BEC5E82823A6
type: Subunit Annotation
comment: Homotetramer.

SIP398A2B09FD33120E
type: PTM Annotation
comment: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.

SIP01F1E3E616F8F281
type: Similarity Annotation
comment: Belongs to the histone-like Alba family.

PRO_0000151716
type: Chain Annotation
comment: DNA/RNA-binding protein Alba
mass: 9938
range: 22862455760827694tt1tt89

22862455760827694tt1
type: Position
type: ExactPosition
position: 1
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR

22862455760827694tt89
type: Position
type: ExactPosition
position: 89
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR

SIP1F12E519870B1716
type: Modified Residue Annotation
comment: N6-acetyllysine
range: 22862455760827694tt12tt12

22862455760827694tt12
type: Position
type: ExactPosition
position: 12
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR

MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 9938

http://purl.uniprot.org/uniprot/Q9HJQ5#attribution-55EE386D4A7E03D47B6D7C2F61E4CAA4
manual: true
evidence: ECO_0000255
source: MF_01122

Q979S5
type: Protein
reviewed: true
created: 2003-09-09
modified: 2023-02-22
version: 99
mnemonic: ALBA_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPFC988FC7BEEA7632
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPD849B793BA648D19
annotation: SIP098BC4AD995D8D6E
annotation: SIP8A65821A47C40C40
annotation: SIP952A64E1D0A1C2AD
annotation: SIP185BBDC4255F3DA4
annotation: PRO_0000151717
annotation: SIPF35DBF9A270A2996
annotation: SIP671C9E49ABBB7573
annotation: SIP63CD40FBEEBFDA30
annotation: SIP1B163EFAE248595E
annotation: SIP33F515BEA3963710
annotation: SIP24ABDD1F44B2839C
annotation: SIPF3B2BA1B3DFECC62
annotation: SIP4B9E2820E68161A5
annotation: SIPE9801D96BC38E90D
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/7
classified with: http://purl.uniprot.org/keywords/158
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/694
classified with: GO_0005694
classified with: GO_0005737
classified with: GO_0003690
classified with: GO_0003723
sequence: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR
proteome: Chromosome

Q979S5-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

4Z9E
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.49
chain sequence mapping: PDB 4Z9E tt1tt89

PDB 4Z9E tt1tt89
chain: A/B/C/D=1-89

SIPFC988FC7BEEA7632
type: Structured Name
full name: DNA/RNA-binding protein Alba

albA
type: Gene
locus name: TV1085
orf name: TVG1115434

SIPD849B793BA648D19
type: Function Annotation
comment: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.

SIP098BC4AD995D8D6E
type: Subunit Annotation
comment: Homotetramer.

SIP952A64E1D0A1C2AD
type: PTM Annotation
comment: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.

SIP185BBDC4255F3DA4
type: Similarity Annotation
comment: Belongs to the histone-like Alba family.

PRO_0000151717
type: Chain Annotation
comment: DNA/RNA-binding protein Alba
mass: 9966
range: 22862382461302062tt1tt89

22862382461302062tt1
type: Position
type: ExactPosition
position: 1
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt89
type: Position
type: ExactPosition
position: 89
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

SIPF35DBF9A270A2996
type: Modified Residue Annotation
comment: N6-acetyllysine
range: 22862382461302062tt12tt12

22862382461302062tt12
type: Position
type: ExactPosition
position: 12
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt6
type: Position
type: ExactPosition
position: 6
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt8
type: Position
type: ExactPosition
position: 8
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt14
type: Position
type: ExactPosition
position: 14
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt25
type: Position
type: ExactPosition
position: 25
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt26
type: Position
type: ExactPosition
position: 26
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt28
type: Position
type: ExactPosition
position: 28
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt30
type: Position
type: ExactPosition
position: 30
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt37
type: Position
type: ExactPosition
position: 37
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt38
type: Position
type: ExactPosition
position: 38
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt40
type: Position
type: ExactPosition
position: 40
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt41
type: Position
type: ExactPosition
position: 41
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt54
type: Position
type: ExactPosition
position: 54
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt60
type: Position
type: ExactPosition
position: 60
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt69
type: Position
type: ExactPosition
position: 69
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt80
type: Position
type: ExactPosition
position: 80
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

22862382461302062tt88
type: Position
type: ExactPosition
position: 88
reference: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR

MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIRLDTETLQGERGSSNVSSIEITLSR
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 9966

http://purl.uniprot.org/uniprot/Q979S5#attribution-55EE386D4A7E03D47B6D7C2F61E4CAA4
manual: true
evidence: ECO_0000255
source: MF_01122

Q6KZJ6
type: Protein
reviewed: true
created: 2005-03-15
modified: 2023-02-22
version: 102
mnemonic: APGM_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIPD183A9882AA7E80F
enzyme: http://purl.uniprot.org/enzyme/5.4.2.12
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIPF069B67F9D87596F
annotation: SIP17E52733891C85E3
annotation: SIPD3B63399708BDB66
annotation: SIP0CEF943DB8232CE7
annotation: PRO_0000138141
annotation: SIP2834B15F74D4246A
annotation: SIPBFF5533FB5C55B5A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/324
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046537
classified with: GO_0046872
classified with: GO_0006096
sequence: Q6KZJ6-1
proteome: Chromosome

Q6KZJ6-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG01696
type: Resource
database: eggNOG
comment: Archaea

cd16011
type: Resource
database: CDD
comment: iPGM_like
signature sequence match: CDD cd16011 match 1

http://purl.uniprot.org/gene3d/3.40.720.10
type: Resource
database: Gene3D
comment: Alkaline Phosphatase, subunit A
signature sequence match: Gene3D 3.40.720.10 match 1
signature sequence match: Gene3D 3.40.720.10 match 2

MF 01402 A
type: Resource
database: HAMAP
comment: ApgM_A
signature sequence match: HAMAP MF 01402 A match 1

IPR017850
type: Resource
database: InterPro
comment: Alkaline_phosphatase_core_sf

IPR023665
type: Resource
database: InterPro
comment: ApgAM_prokaryotes

IPR006124
type: Resource
database: InterPro
comment: Metalloenzyme

IPR004456
type: Resource
database: InterPro
comment: Pglycerate_mutase_ApgM

PTHR31209
type: Resource
database: PANTHER
comment: COFACTOR-INDEPENDENT PHOSPHOGLYCERATE MUTASE
signature sequence match: PANTHER PTHR31209 match 1

PTHR31209:SF0
type: Resource
database: PANTHER
comment: METALLOENZYME DOMAIN-CONTAINING PROTEIN
signature sequence match: PANTHER PTHR31209:SF0 match 1

PF01676
type: Resource
database: Pfam
comment: Metalloenzyme
signature sequence match: Pfam PF01676 match 1

PF10143
type: Resource
database: Pfam
comment: PhosphMutase
signature sequence match: Pfam PF10143 match 1

PIRSF006392
type: Resource
database: PIRSF
comment: IPGAM_arch
signature sequence match: PIRSF PIRSF006392 match 1

SSF53649
type: Resource
database: SUPFAM
comment: Alkaline phosphatase-like
signature sequence match: SUPFAM SSF53649 match 1

TIGR00306
type: Resource
database: TIGRFAMs
comment: apgM
signature sequence match: TIGRFAMs TIGR00306 match 1

SIPD183A9882AA7E80F
type: Structured Name
full name: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
short name: BPG-independent PGAM
short name: Phosphoglyceromutase
short name: aPGAM
ec name: 5.4.2.12

apgM
type: Gene
locus name: PTO1271

SIPF069B67F9D87596F
type: Function Annotation
comment: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

SIP0CEF943DB8232CE7
type: Similarity Annotation
comment: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

PRO_0000138141
type: Chain Annotation
comment: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
mass: 44552
range: 22859170378823214tt1tt402

22859170378823214tt1
type: Position
type: ExactPosition
position: 1
reference: Q6KZJ6-1

22859170378823214tt402
type: Position
type: ExactPosition
position: 402
reference: Q6KZJ6-1

SIP2834B15F74D4246A
type: Region Annotation
comment: Disordered
range: 22859170378823214tt155tt174

22859170378823214tt155
type: Position
type: ExactPosition
position: 155
reference: Q6KZJ6-1

22859170378823214tt174
type: Position
type: ExactPosition
position: 174
reference: Q6KZJ6-1

SIPBFF5533FB5C55B5A
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 22859170378823214tt160tt174

22859170378823214tt160
type: Position
type: ExactPosition
position: 160
reference: Q6KZJ6-1

Q6KZJ6-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 44552
value: MKNIVLLIMDGLGDNPNPEFFGKTALQAAYRPNLNALCRKSICGLMDPVGPGIRSGSDTSHLSILGYSPERYYNGRGPFEALGLGMELYPGDVAFRANYAYVSDGYVLDRRAGRIRDTCELSRAVSMEIEDVKITVKSGTEHRAAIVMHGPGLSSMVSDSDPHRENERPMEVRPLDKKAEKTARILNEFIKKSREILNKHPVNIKRMNQGLMPANEILIRGAGMVPDLEDFYDRYHLKAACISGTPLIKGICRLAGMDIINMDNLTGRVDENYSGIFEKAHELAKKYDFIIINIKGTDIAGHDRRPDIKRSVIENVDSAISKIINDLDDLLIIVTGDHSTPCNLGDHSGDPVPIMFSSNNIRSDNVMLFDETSVRNGSLRIRGLDVMKIALSLSNRSEKYGA

http://purl.uniprot.org/uniprot/Q6KZJ6#attribution-177E28A52F98AEF8E1D764E5698AF3EF
manual: true
evidence: ECO_0000255
source: MF_01402

Q9HL27
type: Protein
reviewed: true
created: 2002-05-02
modified: 2023-02-22
version: 119
mnemonic: APGM_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPD183A9882AA7E80F
enzyme: http://purl.uniprot.org/enzyme/5.4.2.12
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP868670E3E1AE8865
annotation: SIPA1BB63139618D139
annotation: SIPF5DB286A8F7CD5F9
annotation: SIPA2A3BD758E2FED0F
annotation: PRO_0000138150
annotation: SIP1DDFBC406A3ADD19
annotation: SIP36396C51159B3B3F
annotation: SIPF73CC0468CAFC4EA
annotation: SIPA2EBCCBD85A642AC
annotation: SIPF0A50DDA51881AF9
annotation: SIPE74472AF8CE1BF2A
annotation: SIP2914A053D4B89B6C
annotation: SIP47A3A0C0C677B2A3
annotation: SIP04AE429DD7645000
annotation: SIP09C925792035377B
annotation: SIPE9FC61841FE21B8B
annotation: SIP7CF0E7F8EDD58201
annotation: SIPC3E45056D34BD41C
annotation: SIPBA9EDAA665163FA4
annotation: SIP9927077179652516
annotation: SIP17597386862D68BC
annotation: SIP1AFD672ED9D3BF0D
annotation: SIP1B1F82D4FD224AD4
annotation: SIPC4AF83924F221108
annotation: SIPF05DCF6ED42D8C68
annotation: SIP91517AF28FD32CA6
annotation: SIP475B533A6F937677
annotation: SIP34193D1F24417B26
annotation: SIPF9142BC60F119DAF
annotation: SIP09903472135D0B8E
annotation: SIP4E7A8C2CB474719C
annotation: SIP89E479EB3957F6E1
annotation: SIPBBFA789B7D59FD62
annotation: SIPB2EECB37BF9A8575
annotation: SIPED9A33E4F3D4BDDF
annotation: SIP7CE778C5A95B3CEE
annotation: SIPD4DA4A44B8066BD7
annotation: SIP667C52428333E8AD
annotation: SIP68BB098C6EE82F36
annotation: SIPC6667EB1DD7D6C73
annotation: SIPFF9F44116818A496
annotation: SIPBE8D7A60AF0CAE0E
annotation: SIP4A4A9A4FCBB32C9D
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/324
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046537
classified with: GO_0046872
classified with: GO_0006096
sequence: Q9HL27-1
proteome: Chromosome

Q9HL27-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

3IDD
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.80
chain sequence mapping: PDB 3IDD tt1tt404

PDB 3IDD tt1tt404
chain: A/B=1-404

3KD8
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.60
chain sequence mapping: PDB 3KD8 tt2tt397

PDB 3KD8 tt2tt397
chain: A/B=2-397

http://purl.uniprot.org/brenda/5.4.2.12
type: Resource
database: BRENDA
comment: 6324

http://purl.uniprot.org/gene3d/3.30.70.2130
type: Resource
database: Gene3D
comment: Metalloenzyme domain
signature sequence match: Gene3D 3.30.70.2130 match 1

IPR042253
type: Resource
database: InterPro
comment: Pglycerate_mutase_ApgM_sf

SIPD183A9882AA7E80F
type: Structured Name
full name: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
short name: BPG-independent PGAM
short name: Phosphoglyceromutase
short name: aPGAM
ec name: 5.4.2.12

apgM
type: Gene
locus name: Ta0413

SIP868670E3E1AE8865
type: Function Annotation
comment: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

SIPA2A3BD758E2FED0F
type: Similarity Annotation
comment: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

PRO_0000138150
type: Chain Annotation
comment: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
mass: 43933
range: 22862455792351022tt1tt404

22862455792351022tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HL27-1

22862455792351022tt404
type: Position
type: ExactPosition
position: 404
reference: Q9HL27-1

SIP1DDFBC406A3ADD19
type: Region Annotation
comment: Disordered
range: 22862455792351022tt155tt183

22862455792351022tt155
type: Position
type: ExactPosition
position: 155
reference: Q9HL27-1

22862455792351022tt183
type: Position
type: ExactPosition
position: 183
reference: Q9HL27-1

SIP36396C51159B3B3F
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 22862455792351022tt159tt180

22862455792351022tt159
type: Position
type: ExactPosition
position: 159
reference: Q9HL27-1

22862455792351022tt180
type: Position
type: ExactPosition
position: 180
reference: Q9HL27-1

22862455792351022tt4
type: Position
type: ExactPosition
position: 4
reference: Q9HL27-1

22862455792351022tt12
type: Position
type: ExactPosition
position: 12
reference: Q9HL27-1

22862455792351022tt19
type: Position
type: ExactPosition
position: 19
reference: Q9HL27-1

22862455792351022tt22
type: Position
type: ExactPosition
position: 22
reference: Q9HL27-1

22862455792351022tt26
type: Position
type: ExactPosition
position: 26
reference: Q9HL27-1

22862455792351022tt29
type: Position
type: ExactPosition
position: 29
reference: Q9HL27-1

22862455792351022tt33
type: Position
type: ExactPosition
position: 33
reference: Q9HL27-1

22862455792351022tt40
type: Position
type: ExactPosition
position: 40
reference: Q9HL27-1

22862455792351022tt42
type: Position
type: ExactPosition
position: 42
reference: Q9HL27-1

22862455792351022tt48
type: Position
type: ExactPosition
position: 48
reference: Q9HL27-1

22862455792351022tt62
type: Position
type: ExactPosition
position: 62
reference: Q9HL27-1

22862455792351022tt65
type: Position
type: ExactPosition
position: 65
reference: Q9HL27-1

22862455792351022tt70
type: Position
type: ExactPosition
position: 70
reference: Q9HL27-1

22862455792351022tt73
type: Position
type: ExactPosition
position: 73
reference: Q9HL27-1

22862455792351022tt77
type: Position
type: ExactPosition
position: 77
reference: Q9HL27-1

22862455792351022tt84
type: Position
type: ExactPosition
position: 84
reference: Q9HL27-1

22862455792351022tt94
type: Position
type: ExactPosition
position: 94
reference: Q9HL27-1

22862455792351022tt110
type: Position
type: ExactPosition
position: 110
reference: Q9HL27-1

22862455792351022tt113
type: Position
type: ExactPosition
position: 113
reference: Q9HL27-1

22862455792351022tt115
type: Position
type: ExactPosition
position: 115
reference: Q9HL27-1

22862455792351022tt120
type: Position
type: ExactPosition
position: 120
reference: Q9HL27-1

22862455792351022tt126
type: Position
type: ExactPosition
position: 126
reference: Q9HL27-1

22862455792351022tt129
type: Position
type: ExactPosition
position: 129
reference: Q9HL27-1

22862455792351022tt131
type: Position
type: ExactPosition
position: 131
reference: Q9HL27-1

22862455792351022tt134
type: Position
type: ExactPosition
position: 134
reference: Q9HL27-1

22862455792351022tt140
type: Position
type: ExactPosition
position: 140
reference: Q9HL27-1

22862455792351022tt145
type: Position
type: ExactPosition
position: 145
reference: Q9HL27-1

22862455792351022tt152
type: Position
type: ExactPosition
position: 152
reference: Q9HL27-1

22862455792351022tt176
type: Position
type: ExactPosition
position: 176
reference: Q9HL27-1

22862455792351022tt178
type: Position
type: ExactPosition
position: 178
reference: Q9HL27-1

22862455792351022tt179
type: Position
type: ExactPosition
position: 179
reference: Q9HL27-1

22862455792351022tt181
type: Position
type: ExactPosition
position: 181
reference: Q9HL27-1

22862455792351022tt182
type: Position
type: ExactPosition
position: 182
reference: Q9HL27-1

22862455792351022tt200
type: Position
type: ExactPosition
position: 200
reference: Q9HL27-1

22862455792351022tt203
type: Position
type: ExactPosition
position: 203
reference: Q9HL27-1

22862455792351022tt210
type: Position
type: ExactPosition
position: 210
reference: Q9HL27-1

22862455792351022tt218
type: Position
type: ExactPosition
position: 218
reference: Q9HL27-1

22862455792351022tt226
type: Position
type: ExactPosition
position: 226
reference: Q9HL27-1

22862455792351022tt233
type: Position
type: ExactPosition
position: 233
reference: Q9HL27-1

22862455792351022tt237
type: Position
type: ExactPosition
position: 237
reference: Q9HL27-1

22862455792351022tt241
type: Position
type: ExactPosition
position: 241
reference: Q9HL27-1

22862455792351022tt244
type: Position
type: ExactPosition
position: 244
reference: Q9HL27-1

22862455792351022tt248
type: Position
type: ExactPosition
position: 248
reference: Q9HL27-1

22862455792351022tt256
type: Position
type: ExactPosition
position: 256
reference: Q9HL27-1

22862455792351022tt260
type: Position
type: ExactPosition
position: 260
reference: Q9HL27-1

22862455792351022tt262
type: Position
type: ExactPosition
position: 262
reference: Q9HL27-1

22862455792351022tt275
type: Position
type: ExactPosition
position: 275
reference: Q9HL27-1

22862455792351022tt285
type: Position
type: ExactPosition
position: 285
reference: Q9HL27-1

22862455792351022tt286
type: Position
type: ExactPosition
position: 286
reference: Q9HL27-1

22862455792351022tt288
type: Position
type: ExactPosition
position: 288
reference: Q9HL27-1

22862455792351022tt290
type: Position
type: ExactPosition
position: 290
reference: Q9HL27-1

22862455792351022tt297
type: Position
type: ExactPosition
position: 297
reference: Q9HL27-1

22862455792351022tt308
type: Position
type: ExactPosition
position: 308
reference: Q9HL27-1

22862455792351022tt320
type: Position
type: ExactPosition
position: 320
reference: Q9HL27-1

22862455792351022tt321
type: Position
type: ExactPosition
position: 321
reference: Q9HL27-1

22862455792351022tt326
type: Position
type: ExactPosition
position: 326
reference: Q9HL27-1

22862455792351022tt329
type: Position
type: ExactPosition
position: 329
reference: Q9HL27-1

22862455792351022tt331
type: Position
type: ExactPosition
position: 331
reference: Q9HL27-1

22862455792351022tt332
type: Position
type: ExactPosition
position: 332
reference: Q9HL27-1

22862455792351022tt339
type: Position
type: ExactPosition
position: 339
reference: Q9HL27-1

22862455792351022tt354
type: Position
type: ExactPosition
position: 354
reference: Q9HL27-1

22862455792351022tt360
type: Position
type: ExactPosition
position: 360
reference: Q9HL27-1

22862455792351022tt373
type: Position
type: ExactPosition
position: 373
reference: Q9HL27-1

22862455792351022tt375
type: Position
type: ExactPosition
position: 375
reference: Q9HL27-1

22862455792351022tt376
type: Position
type: ExactPosition
position: 376
reference: Q9HL27-1

22862455792351022tt378
type: Position
type: ExactPosition
position: 378
reference: Q9HL27-1

22862455792351022tt379
type: Position
type: ExactPosition
position: 379
reference: Q9HL27-1

22862455792351022tt384
type: Position
type: ExactPosition
position: 384
reference: Q9HL27-1

22862455792351022tt385
type: Position
type: ExactPosition
position: 385
reference: Q9HL27-1

22862455792351022tt387
type: Position
type: ExactPosition
position: 387
reference: Q9HL27-1

22862455792351022tt388
type: Position
type: ExactPosition
position: 388
reference: Q9HL27-1

22862455792351022tt394
type: Position
type: ExactPosition
position: 394
reference: Q9HL27-1

Q9HL27-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 43933
value: MMKSIILIVLDGLGDRPGSDLQNRTPLQAAFRPNLNWLASHGINGIMHPISPGIRCGSDTSHMSLLGYDPKVYYPGRGPFEALGLGMDIRPGDLAFRANFATNRDGVIVDRRAGRENKGNEELADAISLDMGEYSFRVKSGVEHRAALVVSGPDLSDMIGDSDPHREGLPPEKIRPTDPSGDRTAEVMNAYLEEARRILSDHRVNKERVKNGRLPGNELLVRSAGKVPAIPSFTEKNRMKGACVVGSPWLKGLCRLLRMDVFDVPGATGTVGSNYRGKIEKAVDLTSSHDFVLVNIKATDVAGHDGNYPLKRDVIEDIDRAMEPLKSIGDHAVICVTGDHSTPCSFKDHSGDPVPIVFYTDGVMNDGVHLFDELSSASGSLRITSYNVMDILMQLAGRSDKFGS

http://purl.uniprot.org/uniprot/Q9HL27#attribution-177E28A52F98AEF8E1D764E5698AF3EF
manual: true
evidence: ECO_0000255
source: MF_01402

Q979H8
type: Protein
reviewed: true
created: 2002-05-02
modified: 2023-02-22
version: 120
mnemonic: APGM_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPD183A9882AA7E80F
enzyme: http://purl.uniprot.org/enzyme/5.4.2.12
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP6F98792B823C1F28
annotation: SIPA289732A28ACAF8F
annotation: SIPD7698339736C4F5F
annotation: SIP2B459A1FBA0C0955
annotation: PRO_0000138151
annotation: SIP1D23406921CF1DC9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/324
classified with: http://purl.uniprot.org/keywords/413
classified with: GO_0046537
classified with: GO_0046872
classified with: GO_0006096
sequence: Q979H8-1
proteome: Chromosome

Q979H8-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIPD183A9882AA7E80F
type: Structured Name
full name: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
short name: BPG-independent PGAM
short name: Phosphoglyceromutase
short name: aPGAM
ec name: 5.4.2.12

apgM
type: Gene
locus name: TV1183
orf name: TVG1213330

SIP6F98792B823C1F28
type: Function Annotation
comment: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

SIP2B459A1FBA0C0955
type: Similarity Annotation
comment: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

PRO_0000138151
type: Chain Annotation
comment: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
mass: 44101
range: 22862382460581934tt1tt406

22862382460581934tt1
type: Position
type: ExactPosition
position: 1
reference: Q979H8-1

22862382460581934tt406
type: Position
type: ExactPosition
position: 406
reference: Q979H8-1

SIP1D23406921CF1DC9
type: Region Annotation
comment: Disordered
range: 22862382460581934tt156tt183

22862382460581934tt156
type: Position
type: ExactPosition
position: 156
reference: Q979H8-1

22862382460581934tt183
type: Position
type: ExactPosition
position: 183
reference: Q979H8-1

Q979H8-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 44101
value: MIDVKSIILIVLDGLGDRPGEILGYRTPLQAAYHPNMNRMASLGMTGLMHPISPGIRSGSDTSHMSLLGYDPRVYYQGRGPFEALGLHMDMKPGDLAFRANFATNRDGKIIDRRAGRINAGNDQLASAISIDIGNYKFRVKSGVEHRAALVVSGPNLSDKISDSDPHSEGKPPEPIRPLDPSADSTAKIMNEYLKRIREILRDHPVNVEREKNGQIPGNELLIRSAGKVPDIPSFQEKNGITGACVVGSPWLKGLCRLLGMAVIDVPGAAGTINSNYTGKIKTAIDASKRYDFVLVNIKATDVAGHDGDYELKRRVIEDIDIAMEPLLGQSDRIVVAITGDHSTPCSVKDHSGDPVPIVFYTDGIYSDDVKLFDEVSAMKGALRITTQDVLNILMEMAGRAEKFGS

http://purl.uniprot.org/uniprot/Q979H8#attribution-177E28A52F98AEF8E1D764E5698AF3EF
manual: true
evidence: ECO_0000255
source: MF_01402

Q9HII9
type: Protein
reviewed: true
created: 2003-04-23
modified: 2023-05-03
version: 103
mnemonic: ARCC_THEAC
citation: http://purl.uniprot.org/citations/11029001
conflicting sequence: SIP1F591C4965132F60
recommended name: SIPDFCC33931EFF16E4
enzyme: http://purl.uniprot.org/enzyme/2.7.2.2
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP912317F33E5AF5CE
annotation: SIPFFD390B25811F9D4
annotation: SIPCEA1A6E1C9F1A00D
annotation: SIPA960E0CCB08C6697
annotation: SIPD7992C98F9F9A405
annotation: PRO_0000185143
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/56
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0008804
classified with: GO_0006525
classified with: GO_0035975
classified with: GO_0016310
sequence: Q9HII9-1
proteome: Chromosome

Q9HII9-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

EMBL CAC12471.1
comment: Different initiation.

arCOG00863
type: Resource
database: eggNOG
comment: Archaea

cd04235
type: Resource
database: CDD
comment: AAK_CK
signature sequence match: CDD cd04235 match 1

http://purl.uniprot.org/gene3d/3.40.1160.10
type: Resource
database: Gene3D
comment: Acetylglutamate kinase-like
signature sequence match: Gene3D 3.40.1160.10 match 1

IPR036393
type: Resource
database: InterPro
comment: AceGlu_kinase-like_sf

IPR001048
type: Resource
database: InterPro
comment: Asp/Glu/Uridylate_kinase

IPR003964
type: Resource
database: InterPro
comment: Carb_kinase

PTHR30409
type: Resource
database: PANTHER
comment: CARBAMATE KINASE
signature sequence match: PANTHER PTHR30409 match 1

PTHR30409:SF1
type: Resource
database: PANTHER
comment: CARBAMATE KINASE-RELATED
signature sequence match: PANTHER PTHR30409:SF1 match 1

PF00696
type: Resource
database: Pfam
comment: AA_kinase
signature sequence match: Pfam PF00696 match 1

PIRSF000723
type: Resource
database: PIRSF
comment: Carbamate_kin
signature sequence match: PIRSF PIRSF000723 match 1

PR01469
type: Resource
database: PRINTS
comment: CARBMTKINASE

SSF53633
type: Resource
database: SUPFAM
comment: Carbamate kinase-like
signature sequence match: SUPFAM SSF53633 match 1

TIGR00746
type: Resource
database: TIGRFAMs
comment: arcC
signature sequence match: TIGRFAMs TIGR00746 match 1

SIPDFCC33931EFF16E4
type: Structured Name
full name: Carbamate kinase
ec name: 2.7.2.2

arcC
type: Gene
locus name: Ta1350

SIPA960E0CCB08C6697
type: Similarity Annotation
comment: Belongs to the carbamate kinase family.

PRO_0000185143
type: Chain Annotation
comment: Carbamate kinase
mass: 33947
range: 22862455743527214tt1tt305

22862455743527214tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HII9-1

22862455743527214tt305
type: Position
type: ExactPosition
position: 305
reference: Q9HII9-1

Q9HII9-1
type: Simple Sequence
modified: 2003-04-23
version: 2
mass: 33947
value: MSRIVIALGGNALLQNGEKRDYETQYEHAYKTFESLRFVTEDNEVVITHGNGPQVGDIQQSHDISGIGAYLHQSVAMSQGYIGEILANAYTNIKTKYNLRKNIFTIITRVLVDENDPAFSNPEKPIGRYYSDAEVEEARKNGWIMKKFRDGWRRVVPSPDPRQILEEPVIEYLLHNGNLPIAVGGGGVPVVRKGEQIHGIDAVIDKDLASSVLATAIRADFLMILTDVDNVYVNYGKPDQKGLHEVHVEEIEKYLKEGQFGEGSMKPKVMAAIRFIKNGGKKAFITSIENSMNALSGRSGTIIVR

http://purl.uniprot.org/uniprot/Q9HII9#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q97C45
type: Protein
reviewed: true
created: 2003-04-23
modified: 2023-05-03
version: 105
mnemonic: ARCC_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPDFCC33931EFF16E4
enzyme: http://purl.uniprot.org/enzyme/2.7.2.2
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPE622077A5D50701C
annotation: SIP9F90AB7D1A7E1F91
annotation: SIPFAFE0DCD21FA8376
annotation: SIP657580DADE25E0A6
annotation: PRO_0000185144
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/56
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0008804
classified with: GO_0006525
classified with: GO_0035975
classified with: GO_0016310
sequence: Q97C45-1
proteome: Chromosome

Q97C45-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIPDFCC33931EFF16E4
type: Structured Name
full name: Carbamate kinase
ec name: 2.7.2.2

arcC
type: Gene
locus name: TV0260
orf name: TVG0273901

SIP657580DADE25E0A6
type: Similarity Annotation
comment: Belongs to the carbamate kinase family.

PRO_0000185144
type: Chain Annotation
comment: Carbamate kinase
mass: 33464
range: 22862382627042606tt1tt305

22862382627042606tt1
type: Position
type: ExactPosition
position: 1
reference: Q97C45-1

22862382627042606tt305
type: Position
type: ExactPosition
position: 305
reference: Q97C45-1

Q97C45-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 33464
value: MVRIVIALGGNALLRNGEPRNYEVQYSHAIETFKIIRDITEKNETVITHGNGPQVGDIQQSHEISGIMANLHQSVAMSQGYIGEILANAYDEVRSKYSLSKSIFTIITRSVVNRNDPAFASPEKPIGRYYSDQEVDEAKRNGWVMKKFKDGWRRVVPSPEPIEILEEKAIEELVREGHIPLAVGGGGIPVVKENGRIVGIDAVIDKDIASSLLAAQLKADYFMILTDVESVYVNFGKPDQKPLGRIHLNEIEKYYAEGQFADGSMKPKVRAAINFVKNGGKAAFITNLENGSAALSGKAGTVIVP

http://purl.uniprot.org/uniprot/Q97C45#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q9HKC1
type: Protein
reviewed: true
created: 2002-09-19
modified: 2023-02-22
version: 88
mnemonic: ARCH_THEAC
old mnemonic: Y680_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPF8ACABB5487AEE8A
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP3D93DC69CF8A1A9A
annotation: SIPC1EF1812357A3820
annotation: PRO_0000068855
annotation: SIP1FFAB27E8CBB691C
annotation: SIP79CC476056FA4D03
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/106
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005509
classified with: GO_0006388
sequence: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL
proteome: Chromosome

Q9HKC1-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG04055
type: Resource
database: eggNOG
comment: Archaea

http://purl.uniprot.org/gene3d/3.55.10.10
type: Resource
database: Gene3D
comment: Archease domain
signature sequence match: Gene3D 3.55.10.10 match 1

MF_01222
type: Resource
database: HAMAP
comment: Archease_arch
signature sequence match: HAMAP MF 01222 match 1

IPR002804
type: Resource
database: InterPro
comment: Archease

IPR022952
type: Resource
database: InterPro
comment: Archease_arc

IPR023572
type: Resource
database: InterPro
comment: Archease_dom

IPR036820
type: Resource
database: InterPro
comment: Archease_dom_sf

PTHR12682
type: Resource
database: PANTHER
comment: ARCHEASE
signature sequence match: PANTHER PTHR12682 match 1

PTHR12682:SF11
type: Resource
database: PANTHER
comment: PROTEIN ARCHEASE
signature sequence match: PANTHER PTHR12682:SF11 match 1

PF01951
type: Resource
database: Pfam
comment: Archease
signature sequence match: Pfam PF01951 match 1

SSF69819
type: Resource
database: SUPFAM
comment: MTH1598-like
signature sequence match: SUPFAM SSF69819 match 1

SIPF8ACABB5487AEE8A
type: Structured Name
full name: Protein archease

http://purl.uniprot.org/uniprot/Q9HKC1#gene-MD5B28DAA8BECB6DCE81EEF94DB22D8A3EC
type: Gene
locus name: Ta0680

SIP3D93DC69CF8A1A9A
type: Function Annotation
comment: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).

SIPC1EF1812357A3820
type: Similarity Annotation
comment: Belongs to the archease family.

PRO_0000068855
type: Chain Annotation
comment: Protein archease
mass: 16332
range: 22862455776686382tt1tt141

22862455776686382tt1
type: Position
type: ExactPosition
position: 1
reference: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL

22862455776686382tt141
type: Position
type: ExactPosition
position: 141
reference: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL

22862455776686382tt19
type: Position
type: ExactPosition
position: 19
reference: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL

22862455776686382tt140
type: Position
type: ExactPosition
position: 140
reference: MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL

MDSDDNRTLSYEVVDHESDIGVIVYGKTYEELFSNAVYAMADLIVDVSRLKENRKMHEVITGKTPEDIMVNLLSRVLFYLDTYYILYYRITSKYSDGELDAYFYGSEIPEGIEYRNVIKAVTYSDLAVKPEEGYAKIIFDL
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 16332

http://purl.uniprot.org/uniprot/Q9HKC1#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q9HKC1#attribution-43AC33203E39719B1726DA10C06FF249
manual: true
evidence: ECO_0000255
source: MF_01222

Q97A49
type: Protein
reviewed: true
created: 2002-09-19
modified: 2023-02-22
version: 93
mnemonic: ARCH_THEVO
old mnemonic: Y961_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPF8ACABB5487AEE8A
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPDA1CA62E2BF5E5D6
annotation: SIPD7E43577855927D0
annotation: PRO_0000068856
annotation: SIP53D8C29394B5CA77
annotation: SIPDD94EAD8192B165B
annotation: SIP273DEC17C90DAA02
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/106
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005509
classified with: GO_0006388
sequence: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL
proteome: Chromosome

Q97A49-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIPF8ACABB5487AEE8A
type: Structured Name
full name: Protein archease

http://purl.uniprot.org/uniprot/Q97A49#gene-MD5012ED85FF2F45067DB94F64619C55405
type: Gene
locus name: TV0961
orf name: TVG0986240

SIPDA1CA62E2BF5E5D6
type: Function Annotation
comment: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).

SIPD7E43577855927D0
type: Similarity Annotation
comment: Belongs to the archease family.

PRO_0000068856
type: Chain Annotation
comment: Protein archease
mass: 15514
range: 22862382593489198tt1tt133

22862382593489198tt1
type: Position
type: ExactPosition
position: 1
reference: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL

22862382593489198tt133
type: Position
type: ExactPosition
position: 133
reference: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL

22862382593489198tt11
type: Position
type: ExactPosition
position: 11
reference: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL

22862382593489198tt132
type: Position
type: ExactPosition
position: 132
reference: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL

MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 15514

http://purl.uniprot.org/uniprot/Q97A49#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q97A49#attribution-43AC33203E39719B1726DA10C06FF249
manual: true
evidence: ECO_0000255
source: MF_01222

Q9HJP3
type: Protein
reviewed: true
created: 2020-06-17
modified: 2023-02-22
version: 89
mnemonic: ARCSA_THEAC
citation: http://purl.uniprot.org/citations/11029001
citation: http://purl.uniprot.org/citations/31740832
recommended name: SIP5624AE9F608230F1
alternative name: SIP0C482574E1265B97
enzyme: http://purl.uniprot.org/enzyme/4.3.3.-
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPB10321F60350446B
annotation: SIP17D3626915AE6887
annotation: SIP51ADB62C34D56184
annotation: SIP5C3127420C045AD9
annotation: SIP5A37BD51DCF13CBA
annotation: PRO_0000450070
annotation: SIP3821F500D73306C4
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0016829
classified with: GO_0016763
classified with: GO_0003723
classified with: GO_0006400
sequence: Q9HJP3-1
proteome: Chromosome

Q9HJP3-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

Q9HJP3-citation-31740832
type: Citation Statement
scope: FUNCTION
scope: CATALYTIC ACTIVITY
scope: PATHWAY

arCOG00990
type: Resource
database: eggNOG
comment: Archaea

http://purl.uniprot.org/brenda/2.6.1.97
type: Resource
database: BRENDA
comment: 6324

http://purl.uniprot.org/gene3d/2.30.130.10
type: Resource
database: Gene3D
comment: PUA domain
signature sequence match: Gene3D 2.30.130.10 match 1

http://purl.uniprot.org/gene3d/3.20.20.105
type: Resource
database: Gene3D
comment: Queuine tRNA-ribosyltransferase-like
signature sequence match: Gene3D 3.20.20.105 match 1

http://purl.uniprot.org/gene3d/3.40.50.10630
type: Resource
database: Gene3D
comment: Uracil-DNA glycosylase-like
signature sequence match: Gene3D 3.40.50.10630 match 1

IPR040777
type: Resource
database: InterPro
comment: DUF5591

IPR002478
type: Resource
database: InterPro
comment: PUA

IPR015947
type: Resource
database: InterPro
comment: PUA-like_sf

IPR036974
type: Resource
database: InterPro
comment: PUA_sf

IPR036511
type: Resource
database: InterPro
comment: TGT-like_sf

IPR036895
type: Resource
database: InterPro
comment: Uracil-DNA_glycosylase-like_sf

PF17884
type: Resource
database: Pfam
comment: DUF5591
signature sequence match: Pfam PF17884 match 1

PF01472
type: Resource
database: Pfam
comment: PUA
signature sequence match: Pfam PF01472 match 1

SSF88802
type: Resource
database: SUPFAM
comment: Pre-PUA domain
signature sequence match: SUPFAM SSF88802 match 1

SSF88697
type: Resource
database: SUPFAM
comment: PUA domain-like
signature sequence match: SUPFAM SSF88697 match 1

SSF51713
type: Resource
database: SUPFAM
comment: tRNA-guanine transglycosylase
signature sequence match: SUPFAM SSF51713 match 1

SSF52141
type: Resource
database: SUPFAM
comment: Uracil-DNA glycosylase-like
signature sequence match: SUPFAM SSF52141 match 1

PS50890
type: Resource
database: PROSITE
comment: PUA
signature sequence match: PROSITE PS50890 match 1

SIP5624AE9F608230F1
type: Structured Name
full name: Archaeosine synthase subunit alpha
ec name: 4.3.3.-

SIP0C482574E1265B97
type: Structured Name
full name: Archaeosine synthase, lysine transferase subunit

arcS
type: Gene
locus name: Ta0924

SIPB10321F60350446B
type: Function Annotation
comment: Functions in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNAs. Catalyzes the addition of L-lysine to the cyano group of 7-cyano-7-deazaguanine (preQ0)-modified tRNAs at position 15, to generate q0kN15-tRNA, a q0N lysine adduct identified as 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine.

SIP5C3127420C045AD9
type: Subunit Annotation
comment: Forms a robust complex with the archaeosine synthase beta subunit RaSEA, likely an alpha(2)beta(2) heterotetrameric structure. Formation of this complex highly increases lysine transfer activity.

SIP5A37BD51DCF13CBA
type: Similarity Annotation
comment: Belongs to the archaeosine synthase type 1 family.

PRO_0000450070
type: Chain Annotation
comment: Archaeosine synthase subunit alpha
mass: 58243
range: 22862455760761646tt1tt510

22862455760761646tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HJP3-1

22862455760761646tt510
type: Position
type: ExactPosition
position: 510
reference: Q9HJP3-1

SIP3821F500D73306C4
type: Domain Extent Annotation
comment: PUA
range: 22862455760761646tt427tt510

22862455760761646tt427
type: Position
type: ExactPosition
position: 427
reference: Q9HJP3-1

Q9HJP3-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 58243
value: MIEDQALFGYARYGKVDDVVYPSVIASGNGINYGDSDIEILGDRIPRQILYPAKIKQEILETDKLVIIPNGAELVRKPKDLVRIIMDIHSRYGFSKLIMISGISDPYSIPALVYLGISFFDSSILEMEGKMGYRFTPFGIEKADHDVSSENAIFISDMMHIIQRSISDGTLRELIEKAVISSKAAEMVRIADYSYYQDFESVFPVRTPYIKANTIEDLYRPDLIRYRNYISESYVKPDADIALILPCSAKKPYSRSKSHQKVIGALGNLRRFIHEVIVTSPIGIVPRDLEETYPARFYDIPVIGLWYEDEKIMMKRMMSSYMGRNRYRKVIAFIPEDLDFITEAIPYPHEVIEFKSSNLQRLREVIQREIAGGKAVNQKVAKYNSILRYQFGEWILPLVSGYTIRRNYNQDMIVKDGKILFVYNENLGKFTINKASADMFIKNGKFLVEIDDFKPTSNVYAMGVVDATEDIRQEDEVVLVHSGEVRGVGIAKMPARAMIELKKGIAVKVR

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-F1884C1278BD1A50EEFD636F8EC70469
manual: true
evidence: ECO_0000250
source: Q5JHG7

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-B657A141790106326C8A0081AF0C0699
manual: true
evidence: ECO_0000255
source: PRU00161

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-616A6303DD986B8C81F427666C98E0FD
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/31740832

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-3E740149566CF87653B0FB17BFEBF9E5
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/31740832

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-1F7E5C7F23F516F3EC034C190A9A03F9
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-98F4A69882A64D9F40428C95C62F4323
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/31740832

http://purl.uniprot.org/uniprot/Q9HJP3#attribution-6A7BA2D145DE7C8AC12E42A4177E208B
manual: true
evidence: ECO_0000312
source: CAC12053.1

Q6L1G5
type: Protein
reviewed: true
created: 2005-08-30
modified: 2023-02-22
version: 103
mnemonic: AROA_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP2382D67527A97251
annotation: SIPAF15E7EA1BB5E559
annotation: SIPDD552D0DA8848586
annotation: SIP3EFB583F6637CF68
annotation: SIPFA70AF01BAB32F7A
annotation: SIP60242560F26E33B9
annotation: PRO_0000088333
annotation: SIPA70178CAAFFC2DCE
annotation: SIP804A0EFF45D3ADE3
annotation: SIPC816C64821C9739A
annotation: SIP8465FEE39739DFBA
annotation: SIP1677344CE7FB9DB6
annotation: SIP497547DCC692B531
annotation: SIPD71C967D1015C8E4
annotation: SIP80B63656479903E8
annotation: SIP9D56594E71E5332C
annotation: SIP7C0C83A6F703AA18
annotation: SIP09AB68220146228E
annotation: SIP3B298A318A0EE6E6
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q6L1G5-1
proteome: Chromosome

Q6L1G5-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG04134
type: Resource
database: eggNOG
comment: Archaea

cd01556
type: Resource
database: CDD
comment: EPSP_synthase
signature sequence match: CDD cd01556 match 1

http://purl.uniprot.org/gene3d/3.65.10.10
type: Resource
database: Gene3D
comment: Enolpyruvate transferase domain
signature sequence match: Gene3D 3.65.10.10 match 1
signature sequence match: Gene3D 3.65.10.10 match 2

MF_00210
type: Resource
database: HAMAP
comment: EPSP_synth
signature sequence match: HAMAP MF 00210 match 1

IPR001986
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_dom

IPR036968
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_sf

IPR006264
type: Resource
database: InterPro
comment: EPSP_synthase

IPR013792
type: Resource
database: InterPro
comment: RNA3'P_cycl/enolpyr_Trfase_a/b

PTHR21090
type: Resource
database: PANTHER
comment: AROM/DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR21090 match 1

PTHR21090:SF5
type: Resource
database: PANTHER
comment: PENTAFUNCTIONAL AROM POLYPEPTIDE
signature sequence match: PANTHER PTHR21090:SF5 match 1

PF00275
type: Resource
database: Pfam
comment: EPSP_synthase
signature sequence match: Pfam PF00275 match 1

PIRSF000505
type: Resource
database: PIRSF
comment: EPSPS
signature sequence match: PIRSF PIRSF000505 match 1

SSF55205
type: Resource
database: SUPFAM
comment: EPT/RTPC-like
signature sequence match: SUPFAM SSF55205 match 1

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: PTO0602

SIP2382D67527A97251
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIP3EFB583F6637CF68
type: Subunit Annotation
comment: Monomer.

SIP60242560F26E33B9
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_0000088333
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 45737
range: 22859173985727790tt1tt411

22859173985727790tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L1G5-1

22859173985727790tt411
type: Position
type: ExactPosition
position: 411
reference: Q6L1G5-1

SIPA70178CAAFFC2DCE
type: Region Annotation
comment: Phosphoenolpyruvate
range: 22859173985727790tt84tt87

22859173985727790tt84
type: Position
type: ExactPosition
position: 84
reference: Q6L1G5-1

22859173985727790tt87
type: Position
type: ExactPosition
position: 87
reference: Q6L1G5-1

SIP804A0EFF45D3ADE3
type: Active Site Annotation
comment: Proton acceptor
range: 22859173985727790tt295tt295

22859173985727790tt295
type: Position
type: ExactPosition
position: 295
reference: Q6L1G5-1

SIPC816C64821C9739A
type: Active Site Annotation
comment: Proton donor
range: 22859173985727790tt323tt323

22859173985727790tt323
type: Position
type: ExactPosition
position: 323
reference: Q6L1G5-1

22859173985727790tt20
type: Position
type: ExactPosition
position: 20
reference: Q6L1G5-1

22859173985727790tt21
type: Position
type: ExactPosition
position: 21
reference: Q6L1G5-1

22859173985727790tt25
type: Position
type: ExactPosition
position: 25
reference: Q6L1G5-1

22859173985727790tt114
type: Position
type: ExactPosition
position: 114
reference: Q6L1G5-1

22859173985727790tt156
type: Position
type: ExactPosition
position: 156
reference: Q6L1G5-1

22859173985727790tt158
type: Position
type: ExactPosition
position: 158
reference: Q6L1G5-1

22859173985727790tt181
type: Position
type: ExactPosition
position: 181
reference: Q6L1G5-1

22859173985727790tt322
type: Position
type: ExactPosition
position: 322
reference: Q6L1G5-1

22859173985727790tt326
type: Position
type: ExactPosition
position: 326
reference: Q6L1G5-1

22859173985727790tt367
type: Position
type: ExactPosition
position: 367
reference: Q6L1G5-1

22859173985727790tt393
type: Position
type: ExactPosition
position: 393
reference: Q6L1G5-1

Q6L1G5-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 45737
value: MNVRISGEFRPGVINAPSSKSFSQRYILYSAFSNIPVTLKNVSFSDDERIALEIARACGADIEFNDSLTIKPDFRCPDEINAGESGTSLRLATGLLAARRCKTFIHEEASLLKRPLDDLIKTLSEKNVVFNNLDNGIMIDASNSIPSDSIIDGGRSSQFVSSMMMYHSLTSGSLKALNIVSNDYIKITIKTLNDFGISVYSSNGFFEFGKTLMKGNKICIEGDYSSAAFWIVLGLFKGDIEIKNLKSDSCQPDAAIINIINGISERKIDIYNNKIVVHKTRFLGDLYIDVDKNPDLAPPLSIIGIFSDVAVHILNYRRLEIKESNREENIISMARSFGALIEKNDNEMVIRRGKISLPERISFSDHRMIMSSIIAGLISSGDILYENIENINKSYPGFLNDLSNLGYYILK

http://purl.uniprot.org/uniprot/Q6L1G5#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

Q9HLE6
type: Protein
reviewed: true
created: 2001-04-27
modified: 2023-02-22
version: 119
mnemonic: AROA_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP79F25A52D7CB467C
annotation: SIP846D8B7574185267
annotation: SIPB4616E46D3BCE5E0
annotation: SIP225E1F6047BC0996
annotation: SIP0250FD0371F7F06F
annotation: SIP0E5209A5507AE516
annotation: PRO_0000088339
annotation: SIPBECDA39891FC7FA0
annotation: SIP070AC4B815D1C45E
annotation: SIP471254E3A9B40A08
annotation: SIP6F7C731727215BEC
annotation: SIP10B40D60B6F02377
annotation: SIP68E6EE02AD2AFB78
annotation: SIP1C9ACCF709E27EF4
annotation: SIP74733F091158C92E
annotation: SIP5C267A683D1388D7
annotation: SIP21BF217AB994B1A3
annotation: SIPEE74BCCCB815748C
annotation: SIPCCDA1AE0405B1F21
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q9HLE6-1
proteome: Chromosome

Q9HLE6-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

IPR023193
type: Resource
database: InterPro
comment: EPSP_synthase_CS

PS00885
type: Resource
database: PROSITE
comment: EPSP_SYNTHASE_2
signature sequence match: PROSITE PS00885 match 1

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: Ta0282

SIP79F25A52D7CB467C
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIP225E1F6047BC0996
type: Subunit Annotation
comment: Monomer.

SIP0E5209A5507AE516
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_0000088339
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 45166
range: 22862455793595950tt1tt410

22862455793595950tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HLE6-1

22862455793595950tt410
type: Position
type: ExactPosition
position: 410
reference: Q9HLE6-1

SIPBECDA39891FC7FA0
type: Region Annotation
comment: Phosphoenolpyruvate
range: 22862455793595950tt85tt88

22862455793595950tt85
type: Position
type: ExactPosition
position: 85
reference: Q9HLE6-1

22862455793595950tt88
type: Position
type: ExactPosition
position: 88
reference: Q9HLE6-1

SIP070AC4B815D1C45E
type: Active Site Annotation
comment: Proton acceptor
range: 22862455793595950tt293tt293

22862455793595950tt293
type: Position
type: ExactPosition
position: 293
reference: Q9HLE6-1

SIP471254E3A9B40A08
type: Active Site Annotation
comment: Proton donor
range: 22862455793595950tt321tt321

22862455793595950tt321
type: Position
type: ExactPosition
position: 321
reference: Q9HLE6-1

22862455793595950tt20
type: Position
type: ExactPosition
position: 20
reference: Q9HLE6-1

22862455793595950tt21
type: Position
type: ExactPosition
position: 21
reference: Q9HLE6-1

22862455793595950tt25
type: Position
type: ExactPosition
position: 25
reference: Q9HLE6-1

22862455793595950tt115
type: Position
type: ExactPosition
position: 115
reference: Q9HLE6-1

22862455793595950tt157
type: Position
type: ExactPosition
position: 157
reference: Q9HLE6-1

22862455793595950tt159
type: Position
type: ExactPosition
position: 159
reference: Q9HLE6-1

22862455793595950tt183
type: Position
type: ExactPosition
position: 183
reference: Q9HLE6-1

22862455793595950tt320
type: Position
type: ExactPosition
position: 320
reference: Q9HLE6-1

22862455793595950tt324
type: Position
type: ExactPosition
position: 324
reference: Q9HLE6-1

22862455793595950tt365
type: Position
type: ExactPosition
position: 365
reference: Q9HLE6-1

22862455793595950tt391
type: Position
type: ExactPosition
position: 391
reference: Q9HLE6-1

Q9HLE6-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 45166
value: MTVKIYGSGGSGTVALPSSKSFTQRYILGSVFLNKSVTLNYVTITGDDSIALDIAQRAGANITMNDSSIKIRTSFTCPSDIYVGESATSYRIALGLLGSAGCITHVKGDPDLAKRPMDPLVKALEANDVHLKLNEDGFYDVDGSESKKRYIEVDGVSSQFVSSMIFYYARKGGGEFLVKNMRSPGYVYITKRVLYDLGYFVNIEKTITINPSGVWKTAIDVEPDYSSLAFFLVLGLLSENVDVRFNIKRMSRIQPDSVLLDMFKDNIAIDRDTLRVLPGIRDRITVDADHNPDLCPPISVIGIFSEHGVEIDNYARLKTKESNRYEGIIDMASRFGAIVEDNGKDLFIKRGDLKDPGTLSYTDHRMIMSAAVAAAASGFEVEIENETKVSKSFPGFFKELSKFANVSESN

http://purl.uniprot.org/uniprot/Q9HLE6#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

http://purl.uniprot.org/uniprot/Q9HLE6#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q978S3
type: Protein
reviewed: true
created: 2002-06-06
modified: 2023-02-22
version: 115
mnemonic: AROA_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPFA203C275D6F9816
annotation: SIP75226906A31AAD66
annotation: SIPCA582AED916E3CB6
annotation: SIPCA169F5D35B48261
annotation: SIPAC7045DCD659B908
annotation: SIP15438C54151F36CA
annotation: PRO_0000088340
annotation: SIP1073ED84538C8089
annotation: SIP840ACA40FFC0AC96
annotation: SIP1A85AB12D1AAD4C0
annotation: SIP9CDB517EFEEF73C8
annotation: SIP4C634249E2F78EA1
annotation: SIP09D04C9A19212C9D
annotation: SIP0396151FE00EF7E7
annotation: SIPDD0175177D0EE188
annotation: SIP8BCC1FFD9FEC2BC5
annotation: SIP678A6C060175DFA7
annotation: SIPFB974B15498986EB
annotation: SIP9CEB9B380A4D1D61
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q978S3-1
proteome: Chromosome

Q978S3-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: TV1342
orf name: TVG1387115

SIPFA203C275D6F9816
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIPCA169F5D35B48261
type: Subunit Annotation
comment: Monomer.

SIP15438C54151F36CA
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_0000088340
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 45187
range: 22862382444524334tt1tt410

22862382444524334tt1
type: Position
type: ExactPosition
position: 1
reference: Q978S3-1

22862382444524334tt410
type: Position
type: ExactPosition
position: 410
reference: Q978S3-1

SIP1073ED84538C8089
type: Region Annotation
comment: Phosphoenolpyruvate
range: 22862382444524334tt85tt88

22862382444524334tt85
type: Position
type: ExactPosition
position: 85
reference: Q978S3-1

22862382444524334tt88
type: Position
type: ExactPosition
position: 88
reference: Q978S3-1

SIP840ACA40FFC0AC96
type: Active Site Annotation
comment: Proton acceptor
range: 22862382444524334tt293tt293

22862382444524334tt293
type: Position
type: ExactPosition
position: 293
reference: Q978S3-1

SIP1A85AB12D1AAD4C0
type: Active Site Annotation
comment: Proton donor
range: 22862382444524334tt321tt321

22862382444524334tt321
type: Position
type: ExactPosition
position: 321
reference: Q978S3-1

22862382444524334tt20
type: Position
type: ExactPosition
position: 20
reference: Q978S3-1

22862382444524334tt21
type: Position
type: ExactPosition
position: 21
reference: Q978S3-1

22862382444524334tt25
type: Position
type: ExactPosition
position: 25
reference: Q978S3-1

22862382444524334tt115
type: Position
type: ExactPosition
position: 115
reference: Q978S3-1

22862382444524334tt157
type: Position
type: ExactPosition
position: 157
reference: Q978S3-1

22862382444524334tt159
type: Position
type: ExactPosition
position: 159
reference: Q978S3-1

22862382444524334tt183
type: Position
type: ExactPosition
position: 183
reference: Q978S3-1

22862382444524334tt320
type: Position
type: ExactPosition
position: 320
reference: Q978S3-1

22862382444524334tt324
type: Position
type: ExactPosition
position: 324
reference: Q978S3-1

22862382444524334tt365
type: Position
type: ExactPosition
position: 365
reference: Q978S3-1

22862382444524334tt391
type: Position
type: ExactPosition
position: 391
reference: Q978S3-1

Q978S3-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 45187
value: MIVKVSNLGGSGIAEMPSSKSFTQRYVLASAFLNKSVVLNGITITNDDDVAMRIAESVGSTITINNRSIKISSNFKCPEEIYVGESGTSYRLSIGLLAASGCVTRIKGEDSLAKRPIEPLLMALGENGVKFERNEAGFYNVDGRNSQKKHVEIEGSSSQFVSSLMLYYAKKGGGEFTARNIKSIGYVYITKRVLYDLGYFANIERTITINPTGVWKTAIDVEPDYSSMAFFMVLGLLSDSVDVRFRIKRISRIQPDSVILDLFKNNILINGEEIRVISGINEPVSVDADMNPDLCPPLSVIGIFSKYGVQIRNYERLKTKESNRYEGIIDLAERFGANVEDNGQDLFIKPGSVRFPDVISYKDHRMIMAASIASLIGGFPTVIENAEKTAKSFPGFFAELSKFANVEELA

http://purl.uniprot.org/uniprot/Q978S3#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

Q6L1G8
type: Protein
reviewed: true
created: 2005-08-30
modified: 2023-05-03
version: 107
mnemonic: AROB_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP42090E3E8A48117E
annotation: SIP369B67B5C2F9A844
annotation: SIP2FDEBBC035321850
annotation: SIPC6C77E42AB510F45
annotation: SIP6A4341943F7A489C
annotation: SIP320FD048FD2339F2
annotation: SIP4C51C1A6F3942E50
annotation: PRO_0000140816
annotation: SIPFD89565880DF3AA9
annotation: SIPBBBB0CC428A390DF
annotation: SIP9730FBF535E6BB66
annotation: SIP97FAF6189D8A6DA7
annotation: SIP7E9A8F2568F2F806
annotation: SIP638D85AE24589F3E
annotation: SIP551592CE1FD304C3
annotation: SIPB33DE74FFF800657
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q6L1G8-1
proteome: Chromosome

Q6L1G8-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG00983
type: Resource
database: eggNOG
comment: Archaea

cd08195
type: Resource
database: CDD
comment: DHQS
signature sequence match: CDD cd08195 match 1

http://purl.uniprot.org/gene3d/1.20.1090.10
type: Resource
database: Gene3D
comment: Dehydroquinate synthase-like - alpha domain
signature sequence match: Gene3D 1.20.1090.10 match 1

IPR030963
type: Resource
database: InterPro
comment: DHQ_synth_fam

IPR030960
type: Resource
database: InterPro
comment: DHQS/DOIS

PTHR43622
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR43622 match 1

PTHR43622:SF1
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR43622:SF1 match 1

PF01761
type: Resource
database: Pfam
comment: DHQ_synthase
signature sequence match: Pfam PF01761 match 1

PIRSF001455
type: Resource
database: PIRSF
comment: DHQ_synth
signature sequence match: PIRSF PIRSF001455 match 1

SSF56796
type: Resource
database: SUPFAM
comment: Dehydroquinate synthase-like
signature sequence match: SUPFAM SSF56796 match 1

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: PTO0599

SIP42090E3E8A48117E
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIPC6C77E42AB510F45
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIP4C51C1A6F3942E50
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_0000140816
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 37756
range: 22859173985728558tt1tt338

22859173985728558tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L1G8-1

22859173985728558tt338
type: Position
type: ExactPosition
position: 338
reference: Q6L1G8-1

22859173985728558tt58
type: Position
type: ExactPosition
position: 58
reference: Q6L1G8-1

22859173985728558tt63
type: Position
type: ExactPosition
position: 63
reference: Q6L1G8-1

22859173985728558tt92
type: Position
type: ExactPosition
position: 92
reference: Q6L1G8-1

22859173985728558tt96
type: Position
type: ExactPosition
position: 96
reference: Q6L1G8-1

22859173985728558tt116
type: Position
type: ExactPosition
position: 116
reference: Q6L1G8-1

22859173985728558tt117
type: Position
type: ExactPosition
position: 117
reference: Q6L1G8-1

22859173985728558tt129
type: Position
type: ExactPosition
position: 129
reference: Q6L1G8-1

22859173985728558tt138
type: Position
type: ExactPosition
position: 138
reference: Q6L1G8-1

22859173985728558tt169
type: Position
type: ExactPosition
position: 169
reference: Q6L1G8-1

22859173985728558tt229
type: Position
type: ExactPosition
position: 229
reference: Q6L1G8-1

22859173985728558tt245
type: Position
type: ExactPosition
position: 245
reference: Q6L1G8-1

Q6L1G8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 37756
value: MDLKYKLGNDVIRIVTGKNILKDFACELNSGGNISIISRNVYKKYDLSFIKNRIIIDDGERAKSMEYLTLIINELLNKRVERGDSIIYIGGGTTGDLSGFAASIYKRGMGLIAVPTTLLAQVDSSIGGKNGINYMNIKNLIGTFYNPKLIIDDISFIDDKKLMMDGLAESLKMGITIEPELFNIINNDPDYIIENIERIITLSINAKLSIVSKDFHDKKHLRYVLNFGHTIGHALESYFNNNISHGEAVANGMIIEAYISKCLGNADISNEIRSIIKRLGFKIIDFRSVDINRLLEYIKNDKKSESGYINIVAVNGIGRYKIEALSPEEMLKILGGMP

http://purl.uniprot.org/uniprot/Q6L1G8#attribution-094C361388864516583E728E9C19FB1B
manual: true
evidence: ECO_0000250
source: P07639

http://purl.uniprot.org/uniprot/Q6L1G8#attribution-C51E2C39D87E23025D9EE4D32AEA3CE1
manual: true
evidence: ECO_0000250
source: P9WPX9

http://purl.uniprot.org/uniprot/Q6L1G8#attribution-212106AD6B5BC6889A9E0AD43158778E
manual: true
evidence: ECO_0000250
source: Q6GGU4

http://purl.uniprot.org/uniprot/Q6L1G8#attribution-122428F402D52605697927C8CB1A8EF7
manual: true
evidence: ECO_0000305

Q9HLE3
type: Protein
reviewed: true
created: 2001-04-27
modified: 2023-05-03
version: 127
mnemonic: AROB_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPDD270E7067552CC6
annotation: SIP4C19E970408C4C7D
annotation: SIP883B7578A9159B36
annotation: SIP741126E1552E157F
annotation: SIP197DFA98163A22F2
annotation: SIP76B788835D6A2091
annotation: SIPCC4CAEA7C3B33360
annotation: PRO_0000140824
annotation: SIP68BBAE220C176A93
annotation: SIPBBC17961D8FA98AE
annotation: SIP5FCAD67B0152CC36
annotation: SIPD32E5F50573AE643
annotation: SIP13AF553F2D8AEE85
annotation: SIP7050FE28CDD57DB6
annotation: SIP96625BFA65D4CB18
annotation: SIPAEF30ECCF5D41BB0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q9HLE3-1
proteome: Chromosome

Q9HLE3-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

IPR016037
type: Resource
database: InterPro
comment: DHQ_synth_AroB

TIGR01357
type: Resource
database: TIGRFAMs
comment: aroB
signature sequence match: TIGRFAMs TIGR01357 match 1

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: Ta0285

SIPDD270E7067552CC6
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIP741126E1552E157F
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIPCC4CAEA7C3B33360
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_0000140824
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 39824
range: 22862455793595182tt1tt360

22862455793595182tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HLE3-1

22862455793595182tt360
type: Position
type: ExactPosition
position: 360
reference: Q9HLE3-1

22862455793595182tt70
type: Position
type: ExactPosition
position: 70
reference: Q9HLE3-1

22862455793595182tt75
type: Position
type: ExactPosition
position: 75
reference: Q9HLE3-1

22862455793595182tt104
type: Position
type: ExactPosition
position: 104
reference: Q9HLE3-1

22862455793595182tt108
type: Position
type: ExactPosition
position: 108
reference: Q9HLE3-1

22862455793595182tt128
type: Position
type: ExactPosition
position: 128
reference: Q9HLE3-1

22862455793595182tt129
type: Position
type: ExactPosition
position: 129
reference: Q9HLE3-1

22862455793595182tt141
type: Position
type: ExactPosition
position: 141
reference: Q9HLE3-1

22862455793595182tt150
type: Position
type: ExactPosition
position: 150
reference: Q9HLE3-1

22862455793595182tt182
type: Position
type: ExactPosition
position: 182
reference: Q9HLE3-1

22862455793595182tt243
type: Position
type: ExactPosition
position: 243
reference: Q9HLE3-1

22862455793595182tt259
type: Position
type: ExactPosition
position: 259
reference: Q9HLE3-1

Q9HLE3-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 39824
value: MDAQRFVLPMNGENISVVIGEDITGHISEEVGHYDSLVFMISRNVEEMFGSKIPPLENYGSSTIKITLNDGESLKTLRNYQRIIKVLVEKKVSRNSLLVYVGGGTVGDLAGFVAATYKRGLRMIAVPTTLLAQVDSSIGGKNGLDFSDVKNVIGTFYNPYLIIDDLQFLKSTPDLIREGMGEVIKYSIIAGGDMFRKVSECSLSNFHDHSADIVKMSIKIKADIVNRDYYDRNGVRSILNLGHTIAHGIEGASKGQISHGRAVATGLMVEAHIGEKYGNTRPEVIDEIMKLADNYGIERVRISDIGVNSILRYISNDKKMSEGYINMPVPADIGNIITMKVTERMISDGLNTFIREHERK

http://purl.uniprot.org/uniprot/Q9HLE3#attribution-094C361388864516583E728E9C19FB1B
manual: true
evidence: ECO_0000250
source: P07639

http://purl.uniprot.org/uniprot/Q9HLE3#attribution-C51E2C39D87E23025D9EE4D32AEA3CE1
manual: true
evidence: ECO_0000250
source: P9WPX9

http://purl.uniprot.org/uniprot/Q9HLE3#attribution-212106AD6B5BC6889A9E0AD43158778E
manual: true
evidence: ECO_0000250
source: Q6GGU4

http://purl.uniprot.org/uniprot/Q9HLE3#attribution-122428F402D52605697927C8CB1A8EF7
manual: true
evidence: ECO_0000305

Q978S6
type: Protein
reviewed: true
created: 2002-08-13
modified: 2023-05-03
version: 125
mnemonic: AROB_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPE136B2A92F55825C
annotation: SIP192DFDCE517DC8CF
annotation: SIP9012C108F725C62D
annotation: SIP4F93891B87BFBC16
annotation: SIP72017C572237F19C
annotation: SIPA6A747F1A0C1DA67
annotation: SIP5475AB4B47E170A8
annotation: PRO_0000140825
annotation: SIPD02C7D05FD8EB66E
annotation: SIP34A9D48220AAE8F1
annotation: SIP368C8EAA89A7724F
annotation: SIP81EC13A555E99992
annotation: SIPF7267C95CEBE09C3
annotation: SIP62A010027DF59A75
annotation: SIP29740814AD8B3FB4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q978S6-1
proteome: Chromosome

Q978S6-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

MF_00110
type: Resource
database: HAMAP
comment: DHQ_synthase
signature sequence match: HAMAP MF 00110 match 1

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: TV1339
orf name: TVG1384310

SIPE136B2A92F55825C
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIP4F93891B87BFBC16
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIP5475AB4B47E170A8
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_0000140825
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 39616
range: 22862382444525102tt1tt360

22862382444525102tt1
type: Position
type: ExactPosition
position: 1
reference: Q978S6-1

22862382444525102tt360
type: Position
type: ExactPosition
position: 360
reference: Q978S6-1

22862382444525102tt70
type: Position
type: ExactPosition
position: 70
reference: Q978S6-1

22862382444525102tt75
type: Position
type: ExactPosition
position: 75
reference: Q978S6-1

22862382444525102tt128
type: Position
type: ExactPosition
position: 128
reference: Q978S6-1

22862382444525102tt129
type: Position
type: ExactPosition
position: 129
reference: Q978S6-1

22862382444525102tt141
type: Position
type: ExactPosition
position: 141
reference: Q978S6-1

22862382444525102tt150
type: Position
type: ExactPosition
position: 150
reference: Q978S6-1

22862382444525102tt182
type: Position
type: ExactPosition
position: 182
reference: Q978S6-1

22862382444525102tt243
type: Position
type: ExactPosition
position: 243
reference: Q978S6-1

22862382444525102tt259
type: Position
type: ExactPosition
position: 259
reference: Q978S6-1

Q978S6-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 39616
value: MDTQRFVITMNGDNISFIVGDNAINHLSEEAGKYDSIVIMISKTVEEMYANHIPDVGSFGNSVVKISLNDGESLKSLRNYQKIVKVLLERKVDRRSLLVYIGGGTVGDLAGFVASTYKRGVMMIAVPTTLLAQVDSSIGGKNGLDFSDVKNVIGTFYNPYMVIDDTVFLKNNSFIIREGMSEVIKYAIISGGDMYDTLNRCSIDNFDACATNIIKLSVKIKSEIVNRDFYDRTGIRSVLNLGHTIAHGIEGATKGSISHGKAVATGMLVEAHIGEKYGNTNHEVIEAIRDLMKRYGIEELNLKEIGPGNILRYISNDKKIMEGYINMPVPSEIGKVITMKATERMISDGINTFIKENDAS

http://purl.uniprot.org/uniprot/Q978S6#attribution-F61B7AC94BE0710BC96CCD11C1C2E895
manual: true
evidence: ECO_0000255
source: MF_00110

Q9HJY7
type: Protein
reviewed: true
created: 2001-01-11
modified: 2023-02-22
version: 108
mnemonic: AROC_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP26EDFBEC82708729
alternative name: SIPE4438FB08936EFF5
enzyme: http://purl.uniprot.org/enzyme/4.2.3.5
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPF186695F8269838A
annotation: SIP4FE561FF98076F75
annotation: SIP48041121512842B9
annotation: SIPB09AC1E9DD21DD0D
annotation: SIP74376939D1063A14
annotation: PRO_0000140699
annotation: SIP12004782E1DF814C
annotation: SIP07C69DA9CB87739C
annotation: SIP56030FF34C22F7ED
annotation: SIP405906BC5E2378B2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/274
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004107
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q9HJY7-1
proteome: Chromosome

Q9HJY7-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG04133
type: Resource
database: eggNOG
comment: Archaea

cd07304
type: Resource
database: CDD
comment: Chorismate_synthase
signature sequence match: CDD cd07304 match 1

http://purl.uniprot.org/gene3d/3.60.150.10
type: Resource
database: Gene3D
comment: Chorismate synthase AroC
signature sequence match: Gene3D 3.60.150.10 match 1

MF_00300
type: Resource
database: HAMAP
comment: Chorismate_synth
signature sequence match: HAMAP MF 00300 match 1

IPR000453
type: Resource
database: InterPro
comment: Chorismate_synth

IPR035904
type: Resource
database: InterPro
comment: Chorismate_synth_AroC_sf

IPR020541
type: Resource
database: InterPro
comment: Chorismate_synthase_CS

PTHR21085
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085 match 1

PTHR21085:SF0
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085:SF0 match 1

PF01264
type: Resource
database: Pfam
comment: Chorismate_synt
signature sequence match: Pfam PF01264 match 1

PIRSF001456
type: Resource
database: PIRSF
comment: Chorismate_synth
signature sequence match: PIRSF PIRSF001456 match 1

SSF103263
type: Resource
database: SUPFAM
comment: Chorismate synthase, AroC
signature sequence match: SUPFAM SSF103263 match 1

TIGR00033
type: Resource
database: TIGRFAMs
comment: aroC
signature sequence match: TIGRFAMs TIGR00033 match 1

PS00787
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_1
signature sequence match: PROSITE PS00787 match 1

PS00788
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_2
signature sequence match: PROSITE PS00788 match 1

PS00789
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_3
signature sequence match: PROSITE PS00789 match 1

SIP26EDFBEC82708729
type: Structured Name
full name: Chorismate synthase
short name: CS
ec name: 4.2.3.5

SIPE4438FB08936EFF5
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate phospholyase

aroC
type: Gene
locus name: Ta0824

SIPF186695F8269838A
type: Function Annotation
comment: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

SIP48041121512842B9
type: Cofactor Annotation
comment: Reduced FMN (FMNH(2)).
cofactor: CHEBI_57618

SIP74376939D1063A14
type: Similarity Annotation
comment: Belongs to the chorismate synthase family.

PRO_0000140699
type: Chain Annotation
comment: Chorismate synthase
mass: 39237
range: 22862455761352494tt1tt360

22862455761352494tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HJY7-1

22862455761352494tt360
type: Position
type: ExactPosition
position: 360
reference: Q9HJY7-1

22862455761352494tt46
type: Position
type: ExactPosition
position: 46
reference: Q9HJY7-1

22862455761352494tt279
type: Position
type: ExactPosition
position: 279
reference: Q9HJY7-1

22862455761352494tt294
type: Position
type: ExactPosition
position: 294
reference: Q9HJY7-1

22862455761352494tt298
type: Position
type: ExactPosition
position: 298
reference: Q9HJY7-1

22862455761352494tt321
type: Position
type: ExactPosition
position: 321
reference: Q9HJY7-1

Q9HJY7-1
type: Simple Sequence
modified: 2001-01-11
version: 1
mass: 39237
value: MFTLGSSMKMTVFGSSHGEAVGSIIDGFPIGFKIPLDYVQKYMEYRRPGSSILTSQRKEDDEVEIISGLHEGYTDGSPLTLIIRNKNVISSYYSEIRENPRPGHSDYTMFLKYGEFRNYEGGGFLSGRMTAPLVAAGSIAKAYLEGMGIKVKSYMRSIGDVECSRVSGEAYSFETRMPDPECDARARELIMRVMKAGDSIGGRIDTVVENFPGGVGEPFFDSVESSIAHAIFSIPAVKAIEFGDGFRLASMLGSEANDPFDLADGKIVTKTNHNGGILGGITNGMPIRFSIAVKPTPSIHIPQQTVNLSTSEKTTITVKGRHDPCVAIRAVPVVECLTSFVLLDLLIQSGNVNRYARKTR

http://purl.uniprot.org/uniprot/Q9HJY7#attribution-2F3E6EDFAEDDC061C716E49B15F505C7
manual: true
evidence: ECO_0000255
source: MF_00300

Q97AR9
type: Protein
reviewed: true
created: 2002-05-27
modified: 2023-02-22
version: 102
mnemonic: AROC_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP26EDFBEC82708729
alternative name: SIPE4438FB08936EFF5
enzyme: http://purl.uniprot.org/enzyme/4.2.3.5
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPCC86ED319B2B6641
annotation: SIPD0CDB7CD7CF2F9D1
annotation: SIP24A0C12A0D02F8E4
annotation: SIP90A4CE5308FEFA7E
annotation: SIPBAEB15497790E934
annotation: PRO_0000140700
annotation: SIPD678644BE7299EAD
annotation: SIP476529357A6C6DCD
annotation: SIP7ABF4D1FF1076130
annotation: SIPE79BBA64D9C62C66
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/274
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/521
classified with: GO_0004107
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q97AR9-1
proteome: Chromosome

Q97AR9-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP26EDFBEC82708729
type: Structured Name
full name: Chorismate synthase
short name: CS
ec name: 4.2.3.5

SIPE4438FB08936EFF5
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate phospholyase

aroC
type: Gene
locus name: TV0740
orf name: TVG0743399

SIPCC86ED319B2B6641
type: Function Annotation
comment: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

SIP24A0C12A0D02F8E4
type: Cofactor Annotation
comment: Reduced FMN (FMNH(2)).
cofactor: CHEBI_57618

SIPBAEB15497790E934
type: Similarity Annotation
comment: Belongs to the chorismate synthase family.

PRO_0000140700
type: Chain Annotation
comment: Chorismate synthase
mass: 40029
range: 22862382595455278tt1tt366

22862382595455278tt1
type: Position
type: ExactPosition
position: 1
reference: Q97AR9-1

22862382595455278tt366
type: Position
type: ExactPosition
position: 366
reference: Q97AR9-1

22862382595455278tt48
type: Position
type: ExactPosition
position: 48
reference: Q97AR9-1

22862382595455278tt281
type: Position
type: ExactPosition
position: 281
reference: Q97AR9-1

22862382595455278tt296
type: Position
type: ExactPosition
position: 296
reference: Q97AR9-1

22862382595455278tt300
type: Position
type: ExactPosition
position: 300
reference: Q97AR9-1

22862382595455278tt323
type: Position
type: ExactPosition
position: 323
reference: Q97AR9-1

Q97AR9-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 40029
value: MVMFYLGNVLKLSLFGSSHGESVGSLVDGFPVGYKIPLDYIQKYMEYRRPGNTIITSQRKEEDVVKIISGMHNGFTDGSPITMIIENKNVISSYYEELKENPRPGHSDYTLYVKYGDFRNYEGGGFLSGRMTAPLVAAGALAKSYLDSLGIKITSYMKSIGEVTCDEIRGDPYNFETRIPDPEKNSLATSLLVDIMKSGDSIGGRIDTIVEGLPPGVGEPFFNSVESEISRAMFSIPAVKAIEFGDGFTLSKMKGSEANDPFTVLDGHILTKTNHNGGILGGMTTGMPVKFSIAVKPTPSIHKKQDTINLISKEKSEITVKGRHDPCVAIRAVPVVECLTAFVLMDLMMMGGFIDRYGNVRGRSLL

http://purl.uniprot.org/uniprot/Q97AR9#attribution-2F3E6EDFAEDDC061C716E49B15F505C7
manual: true
evidence: ECO_0000255
source: MF_00300

Q9HLV9
type: Protein
reviewed: true
created: 2002-04-16
modified: 2023-02-22
version: 101
mnemonic: AROD_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPDE3A72722C0C56D9
alternative name: SIP1653C78A2D211AC7
alternative name: SIPAFFD25EE9F4D710A
enzyme: http://purl.uniprot.org/enzyme/4.2.1.10
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPA5BF4EDEBEC35A89
annotation: SIP39915D5B7B9268C7
annotation: SIP5B6EDC440244AFE4
annotation: SIPF31B79C0CD1495AA
annotation: SIP5F8501B0E07E985A
annotation: PRO_0000138840
annotation: SIPDAC2A5C63BC96B65
annotation: SIP8010CBC4FB0A3B90
annotation: SIP4B0AF752A34749B7
annotation: SIP93A260763F21C774
annotation: SIP91B2C57C605F2909
annotation: SIPA8BB2F2B3BBCBA29
annotation: SIPA6E2A87E747071A8
annotation: SIP29D9CCE3F647D967
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0003855
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q9HLV9-1
proteome: Chromosome

Q9HLV9-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG02097
type: Resource
database: eggNOG
comment: Archaea

cd00502
type: Resource
database: CDD
comment: DHQase_I
signature sequence match: CDD cd00502 match 1

http://purl.uniprot.org/gene3d/3.20.20.70
type: Resource
database: Gene3D
comment: Aldolase class I
signature sequence match: Gene3D 3.20.20.70 match 1

MF_00214
type: Resource
database: HAMAP
comment: AroD
signature sequence match: HAMAP MF 00214 match 1

IPR013785
type: Resource
database: InterPro
comment: Aldolase_TIM

IPR001381
type: Resource
database: InterPro
comment: DHquinase_I

PTHR43699
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE DEHYDRATASE
signature sequence match: PANTHER PTHR43699 match 1

PTHR43699:SF1
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE DEHYDRATASE
signature sequence match: PANTHER PTHR43699:SF1 match 1

PF01487
type: Resource
database: Pfam
comment: DHquinase_I
signature sequence match: Pfam PF01487 match 1

SSF51569
type: Resource
database: SUPFAM
comment: Aldolase
signature sequence match: SUPFAM SSF51569 match 1

SIPDE3A72722C0C56D9
type: Structured Name
full name: 3-dehydroquinate dehydratase
short name: 3-dehydroquinase
ec name: 4.2.1.10

SIP1653C78A2D211AC7
type: Structured Name
full name: Type I DHQase

SIPAFFD25EE9F4D710A
type: Structured Name
full name: Type I dehydroquinase
short name: DHQ1

aroD
type: Gene
locus name: Ta0116

SIPA5BF4EDEBEC35A89
type: Function Annotation
comment: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

SIPF31B79C0CD1495AA
type: Subunit Annotation
comment: Homodimer.

SIP5F8501B0E07E985A
type: Similarity Annotation
comment: Belongs to the type-I 3-dehydroquinase family.

PRO_0000138840
type: Chain Annotation
comment: 3-dehydroquinate dehydratase
mass: 26352
range: 22862455794710830tt1tt228

22862455794710830tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HLV9-1

22862455794710830tt228
type: Position
type: ExactPosition
position: 228
reference: Q9HLV9-1

SIPDAC2A5C63BC96B65
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22862455794710830tt127tt127

22862455794710830tt127
type: Position
type: ExactPosition
position: 127
reference: Q9HLV9-1

SIP8010CBC4FB0A3B90
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 22862455794710830tt150tt150

22862455794710830tt150
type: Position
type: ExactPosition
position: 150
reference: Q9HLV9-1

22862455794710830tt26
type: Position
type: ExactPosition
position: 26
reference: Q9HLV9-1

22862455794710830tt51
type: Position
type: ExactPosition
position: 51
reference: Q9HLV9-1

22862455794710830tt53
type: Position
type: ExactPosition
position: 53
reference: Q9HLV9-1

22862455794710830tt84
type: Position
type: ExactPosition
position: 84
reference: Q9HLV9-1

22862455794710830tt190
type: Position
type: ExactPosition
position: 190
reference: Q9HLV9-1

22862455794710830tt209
type: Position
type: ExactPosition
position: 209
reference: Q9HLV9-1

22862455794710830tt213
type: Position
type: ExactPosition
position: 213
reference: Q9HLV9-1

Q9HLV9-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 26352
value: MPLYSGDKISIGKFVIGNPMPIVVTSVFYEDVSTFVERLQTKVLSDKNLYEIRFDMFTEREISDEEELISAMREMDIDYIFTYRGKDARKYYETAIRKMAPAVDIDMDLIGKLEAKPTVTKVIGSYHTSDSEAMMSALDRMIDSDVDMVKVACSYSEDQEFLGDLKRIIDIRKNRRKPIAYVPMGRTFWRALAGYYVSDIVYAMADRPTAYGQPPADYYYQAFKALFY

http://purl.uniprot.org/uniprot/Q9HLV9#attribution-AA5D28B8D6D44CA4EFA21F42BFC7C935
manual: true
evidence: ECO_0000255
source: MF_00214

Q97CA8
type: Protein
reviewed: true
created: 2002-04-16
modified: 2023-02-22
version: 101
mnemonic: AROD_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPDE3A72722C0C56D9
alternative name: SIP1653C78A2D211AC7
alternative name: SIPAFFD25EE9F4D710A
enzyme: http://purl.uniprot.org/enzyme/4.2.1.10
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP602DE44C38DBB0DA
annotation: SIPE5FF0F7F27177C27
annotation: SIP4D22C2A86F8290E5
annotation: SIP8F690639DCF125D5
annotation: SIPC82F91799DCA4360
annotation: PRO_0000138841
annotation: SIP1299DF7B7AD72E24
annotation: SIPD21703D1F51595CD
annotation: SIPAB9864D0EDA919F9
annotation: SIP9F649B103E7D2997
annotation: SIP63838CB1311C1EC9
annotation: SIP594AC3E25AF9DF4E
annotation: SIPFDD3A13A018EF526
annotation: SIP7C346866531DFA15
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0003855
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q97CA8-1
proteome: Chromosome

Q97CA8-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIPDE3A72722C0C56D9
type: Structured Name
full name: 3-dehydroquinate dehydratase
short name: 3-dehydroquinase
ec name: 4.2.1.10

SIP1653C78A2D211AC7
type: Structured Name
full name: Type I DHQase

SIPAFFD25EE9F4D710A
type: Structured Name
full name: Type I dehydroquinase
short name: DHQ1

aroD
type: Gene
locus name: TV0194
orf name: TVG0199907

SIP602DE44C38DBB0DA
type: Function Annotation
comment: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

SIP8F690639DCF125D5
type: Subunit Annotation
comment: Homodimer.

SIPC82F91799DCA4360
type: Similarity Annotation
comment: Belongs to the type-I 3-dehydroquinase family.

PRO_0000138841
type: Chain Annotation
comment: 3-dehydroquinate dehydratase
mass: 26638
range: 22862382627895342tt1tt230

22862382627895342tt1
type: Position
type: ExactPosition
position: 1
reference: Q97CA8-1

22862382627895342tt230
type: Position
type: ExactPosition
position: 230
reference: Q97CA8-1

SIP1299DF7B7AD72E24
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22862382627895342tt127tt127

22862382627895342tt127
type: Position
type: ExactPosition
position: 127
reference: Q97CA8-1

SIPD21703D1F51595CD
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 22862382627895342tt150tt150

22862382627895342tt150
type: Position
type: ExactPosition
position: 150
reference: Q97CA8-1

22862382627895342tt26
type: Position
type: ExactPosition
position: 26
reference: Q97CA8-1

22862382627895342tt51
type: Position
type: ExactPosition
position: 51
reference: Q97CA8-1

22862382627895342tt53
type: Position
type: ExactPosition
position: 53
reference: Q97CA8-1

22862382627895342tt84
type: Position
type: ExactPosition
position: 84
reference: Q97CA8-1

22862382627895342tt190
type: Position
type: ExactPosition
position: 190
reference: Q97CA8-1

22862382627895342tt209
type: Position
type: ExactPosition
position: 209
reference: Q97CA8-1

22862382627895342tt213
type: Position
type: ExactPosition
position: 213
reference: Q97CA8-1

Q97CA8-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 26638
value: MPIIKSSRVNIGRFTIGGSIPIVIISIFDHDAKSLTEKFETKKLSDKNLYEIRFDLFDKVNIDEELEIIRALDEMDIDYIFTYRGHDPEKIYETAITKMVPAVDMDLSLLNKVNRRSPDTRIMVSYHTDSSKDMIEKLDEMLKANADIVKVACNYKDEKNFFKDLIEIAQRKEISGKPVLFIPMGKSFLRVISAYYVSDMVYAKYDKETAMGQPDPDYYNKAFSLFNYIG

http://purl.uniprot.org/uniprot/Q97CA8#attribution-AA5D28B8D6D44CA4EFA21F42BFC7C935
manual: true
evidence: ECO_0000255
source: MF_00214

Q9HLE4
type: Protein
reviewed: true
created: 2001-04-27
modified: 2023-05-03
version: 121
mnemonic: AROE_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPBD1E1E110AD66A3E
enzyme: http://purl.uniprot.org/enzyme/1.1.1.25
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP43C0B2BAEAF3BA07
annotation: SIP4B9A3D4F64E17A6C
annotation: SIPE0FBED925DE35442
annotation: SIP329F5B7DD09949C5
annotation: SIPA1838E6C53AC006A
annotation: PRO_0000136068
annotation: SIP7E96CBADB3B14850
annotation: SIPD448042D90FFD7E2
annotation: SIP0B9D38501ECC557B
annotation: SIPD5DEFF8548ABD29A
annotation: SIP230217DB5C2F1476
annotation: SIP71A3A446898D1D00
annotation: SIPE4AC940179A8F1FC
annotation: SIPD7E0B6F7E1C7E6FF
annotation: SIP4787BEADB1227DC9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004764
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q9HLE4-1
proteome: Chromosome

Q9HLE4-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG01033
type: Resource
database: eggNOG
comment: Archaea

cd01065
type: Resource
database: CDD
comment: NAD_bind_Shikimate_DH
signature sequence match: CDD cd01065 match 1

http://purl.uniprot.org/gene3d/3.40.50.10860
type: Resource
database: Gene3D
comment: Leucine Dehydrogenase, chain A, domain 1
signature sequence match: Gene3D 3.40.50.10860 match 1

http://purl.uniprot.org/gene3d/3.40.50.720
type: Resource
database: Gene3D
comment: NAD(P)-binding Rossmann-like Domain
signature sequence match: Gene3D 3.40.50.720 match 1

MF_00222
type: Resource
database: HAMAP
comment: Shikimate_DH_AroE
signature sequence match: HAMAP MF 00222 match 1

IPR046346
type: Resource
database: InterPro
comment: Aminoacid_DH-like_N_sf

IPR036291
type: Resource
database: InterPro
comment: NAD(P)-bd_dom_sf

IPR013708
type: Resource
database: InterPro
comment: Shikimate_DH-bd_N

IPR022893
type: Resource
database: InterPro
comment: Shikimate_DH_fam

PTHR21089:SF1
type: Resource
database: PANTHER
comment: BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE/SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC
signature sequence match: PANTHER PTHR21089:SF1 match 1

PTHR21089
type: Resource
database: PANTHER
comment: SHIKIMATE DEHYDROGENASE
signature sequence match: PANTHER PTHR21089 match 1

PF08501
type: Resource
database: Pfam
comment: Shikimate_dh_N
signature sequence match: Pfam PF08501 match 1

SSF53223
type: Resource
database: SUPFAM
comment: Aminoacid dehydrogenase-like, N-terminal domain
signature sequence match: SUPFAM SSF53223 match 1

SSF51735
type: Resource
database: SUPFAM
comment: NAD(P)-binding Rossmann-fold domains
signature sequence match: SUPFAM SSF51735 match 1

SIPBD1E1E110AD66A3E
type: Structured Name
full name: Shikimate dehydrogenase (NADP(+))
short name: SDH
ec name: 1.1.1.25

aroE
type: Gene
locus name: Ta0284

SIP43C0B2BAEAF3BA07
type: Function Annotation
comment: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

SIP329F5B7DD09949C5
type: Subunit Annotation
comment: Homodimer.

SIPA1838E6C53AC006A
type: Similarity Annotation
comment: Belongs to the shikimate dehydrogenase family.

PRO_0000136068
type: Chain Annotation
comment: Shikimate dehydrogenase (NADP(+))
mass: 30013
range: 22862455793595438tt1tt268

22862455793595438tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HLE4-1

22862455793595438tt268
type: Position
type: ExactPosition
position: 268
reference: Q9HLE4-1

SIP7E96CBADB3B14850
type: Active Site Annotation
comment: Proton acceptor
range: 22862455793595438tt66tt66

22862455793595438tt66
type: Position
type: ExactPosition
position: 66
reference: Q9HLE4-1

22862455793595438tt62
type: Position
type: ExactPosition
position: 62
reference: Q9HLE4-1

22862455793595438tt78
type: Position
type: ExactPosition
position: 78
reference: Q9HLE4-1

22862455793595438tt87
type: Position
type: ExactPosition
position: 87
reference: Q9HLE4-1

22862455793595438tt102
type: Position
type: ExactPosition
position: 102
reference: Q9HLE4-1

22862455793595438tt126
type: Position
type: ExactPosition
position: 126
reference: Q9HLE4-1

22862455793595438tt130
type: Position
type: ExactPosition
position: 130
reference: Q9HLE4-1

22862455793595438tt207
type: Position
type: ExactPosition
position: 207
reference: Q9HLE4-1

22862455793595438tt209
type: Position
type: ExactPosition
position: 209
reference: Q9HLE4-1

22862455793595438tt230
type: Position
type: ExactPosition
position: 230
reference: Q9HLE4-1

Q9HLE4-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 30013
value: MNGNSIIGLIGHPVSHSIGQILYNRIFQDMGIDAFYLAMDVHMNVLPAFLKNSFFLKAFNVTIPHKVSIIPFLDDLDEIASQTRSVNLVIREQSRMKGYNTDYYGLDYALSFNQVEIEEKRIVIAGSGGIARTVIRYMLDHGAHRVDVLTRNAQNARRNLDIPGIGLHENIDEDYDIYVNCTPLGTLGDGDPFSTVDFRSGRTGIDLVYNPPDTPFLKRMRNAGGRTVSGLDVFIGQGLRTLELVFGIRPDSIFREYAVEALNEIRKG

http://purl.uniprot.org/uniprot/Q9HLE4#attribution-5C7F524C16633F113A12ABC5480D4824
manual: true
evidence: ECO_0000255
source: MF_00222

Q978S5
type: Protein
reviewed: true
created: 2008-03-18
modified: 2023-05-03
version: 117
mnemonic: AROE_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPBD1E1E110AD66A3E
enzyme: http://purl.uniprot.org/enzyme/1.1.1.25
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPA6D4C351BB9DF10D
annotation: SIP7464EE7736EFF240
annotation: SIPBC1A721334576AAF
annotation: SIPDB5E1B6DF5470F7B
annotation: SIPB442B2C0A55B8EB5
annotation: PRO_0000325186
annotation: SIP0E9390C42B38830A
annotation: SIP53DE99137E41C47F
annotation: SIP29192EB56F2DE200
annotation: SIP6B200BF7A67EBE43
annotation: SIP49CA3711963C119E
annotation: SIPA250A6FAFC6B4358
annotation: SIP088545A0BF4B2E18
annotation: SIP1CE80BAFC4EAD3EE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: GO_0004764
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q978S5-1
proteome: Chromosome

Q978S5-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIPBD1E1E110AD66A3E
type: Structured Name
full name: Shikimate dehydrogenase (NADP(+))
short name: SDH
ec name: 1.1.1.25

aroE
type: Gene
locus name: TV1340
orf name: TVG1385100

SIPA6D4C351BB9DF10D
type: Function Annotation
comment: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

SIPDB5E1B6DF5470F7B
type: Subunit Annotation
comment: Homodimer.

SIPB442B2C0A55B8EB5
type: Similarity Annotation
comment: Belongs to the shikimate dehydrogenase family.

PRO_0000325186
type: Chain Annotation
comment: Shikimate dehydrogenase (NADP(+))
mass: 29461
range: 22862382444524846tt1tt267

22862382444524846tt1
type: Position
type: ExactPosition
position: 1
reference: Q978S5-1

22862382444524846tt267
type: Position
type: ExactPosition
position: 267
reference: Q978S5-1

SIP0E9390C42B38830A
type: Active Site Annotation
comment: Proton acceptor
range: 22862382444524846tt67tt67

22862382444524846tt67
type: Position
type: ExactPosition
position: 67
reference: Q978S5-1

22862382444524846tt63
type: Position
type: ExactPosition
position: 63
reference: Q978S5-1

22862382444524846tt88
type: Position
type: ExactPosition
position: 88
reference: Q978S5-1

22862382444524846tt103
type: Position
type: ExactPosition
position: 103
reference: Q978S5-1

22862382444524846tt127
type: Position
type: ExactPosition
position: 127
reference: Q978S5-1

22862382444524846tt131
type: Position
type: ExactPosition
position: 131
reference: Q978S5-1

22862382444524846tt208
type: Position
type: ExactPosition
position: 208
reference: Q978S5-1

22862382444524846tt210
type: Position
type: ExactPosition
position: 210
reference: Q978S5-1

22862382444524846tt231
type: Position
type: ExactPosition
position: 231
reference: Q978S5-1

Q978S5-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 29461
value: MMPPDYVFGLIGHPVSHSIGQIVYNRYFQKKGLNAIYLSIDIFPETLKYFMSYASKMDGFNVTIPHKISIMDYLDQIDWEARSIGSVNLVKTEDGLLKGFNTDYYGIEYMFKKGGVDVSGKSIVVAGSGGIARTVIHYLIKNNAKSVTVKARDVKLAKNKLNAYDVDIKEYANNDYDIYINCTPLGTEAVGDPFPEVQFGKGKIAVDVVYNPPVTPFLKRAGISGSKTLSGLDLYIGQAIKTLDILTSGCDIDTLINSVRVAVNEVR

http://purl.uniprot.org/uniprot/Q978S5#attribution-5C7F524C16633F113A12ABC5480D4824
manual: true
evidence: ECO_0000255
source: MF_00222

Q9HLE5
type: Protein
reviewed: true
created: 2001-06-01
modified: 2023-02-22
version: 112
mnemonic: AROK_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP6918AA3D5BEFE474
enzyme: http://purl.uniprot.org/enzyme/2.7.1.71
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPD1879205B4213A6F
annotation: SIP7AC1D0CC4AC4422C
annotation: SIP134BB9486D6DAC40
annotation: SIPCABBA22390E6D877
annotation: PRO_0000141580
annotation: SIP75F90F529E9ADB47
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0004765
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
classified with: GO_0016310
sequence: Q9HLE5-1
proteome: Chromosome

Q9HLE5-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG01025
type: Resource
database: eggNOG
comment: Archaea

MF_00370
type: Resource
database: HAMAP
comment: Shik_kinase_arch
signature sequence match: HAMAP MF 00370 match 1

IPR006204
type: Resource
database: InterPro
comment: GHMP_kinase_N_dom

IPR020568
type: Resource
database: InterPro
comment: Ribosomal_S5_D2-typ_fold

IPR014721
type: Resource
database: InterPro
comment: Ribosomal_S5_D2-typ_fold_subgr

IPR010189
type: Resource
database: InterPro
comment: SK_arc

PTHR20861
type: Resource
database: PANTHER
comment: HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE
signature sequence match: PANTHER PTHR20861 match 1

PTHR20861:SF3
type: Resource
database: PANTHER
comment: SHIKIMATE KINASE
signature sequence match: PANTHER PTHR20861:SF3 match 1

PF00288
type: Resource
database: Pfam
comment: GHMP_kinases_N
signature sequence match: Pfam PF00288 match 1

PIRSF005758
type: Resource
database: PIRSF
comment: Shikimt_kin_arch
signature sequence match: PIRSF PIRSF005758 match 1

SSF54211
type: Resource
database: SUPFAM
comment: Ribosomal protein S5 domain 2-like
signature sequence match: SUPFAM SSF54211 match 1

TIGR01920
type: Resource
database: TIGRFAMs
comment: Shik_kin_archae
signature sequence match: TIGRFAMs TIGR01920 match 1

SIP6918AA3D5BEFE474
type: Structured Name
full name: Shikimate kinase
short name: SK
ec name: 2.7.1.71

aroK
type: Gene
locus name: Ta0283

SIPCABBA22390E6D877
type: Similarity Annotation
comment: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.

PRO_0000141580
type: Chain Annotation
comment: Shikimate kinase
mass: 29070
range: 22862455793595694tt1tt268

22862455793595694tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HLE5-1

22862455793595694tt268
type: Position
type: ExactPosition
position: 268
reference: Q9HLE5-1

22862455793595694tt70
type: Position
type: ExactPosition
position: 70
reference: Q9HLE5-1

22862455793595694tt80
type: Position
type: ExactPosition
position: 80
reference: Q9HLE5-1

Q9HLE5-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 29070
value: MKYARVRTHGGVSIISAFIDGMGGAFSIDVPMTVTVREGTCSEEKKISEDIRRYLSIATCFRFTVDSRIPSGYGLKSSSAYILALAKAMAVYSGIDISDMEIMTASADISKNSGLSMTGALDDLCQAMYGGYCLTDNRKMKILRRGRLPEMPVLVCADGDKRSSGKVSIEGHFTNAIRRVEDLAFKGRIFDAAVANGLIYGSIFGMDLRLIGSMLKAGALYSSQSGKGPAIFGIFADRRSAMNARSDIGFGIVTKINNQGIRYWKYDS

http://purl.uniprot.org/uniprot/Q9HLE5#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q9HLE5#attribution-DC036A124EC8E88DF072B29F6D9BB9FE
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/Q9HLE5#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6L1N7
type: Protein
reviewed: true
created: 2005-02-01
modified: 2023-02-22
version: 105
mnemonic: ASSY_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP61A4B13E979BBE2A
alternative name: SIPA9120089B7B542D8
enzyme: http://purl.uniprot.org/enzyme/6.3.4.5
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP0EAA2A7F394CD57D
annotation: SIP2E17EA68A28A04F8
annotation: SIPD103A413C01438BF
annotation: SIP98149D6FDB589722
annotation: SIP9421A434AA62D790
annotation: PRO_0000148682
annotation: SIP04BBE279E7F6615A
annotation: SIPF351C5F12CD671C6
annotation: SIP551CB469C157E3ED
annotation: SIPF132F92D3CA29212
annotation: SIP6F8900166E7500B9
annotation: SIPCF2B2C3466406B15
annotation: SIP810E9E90E26F76D2
annotation: SIP5834D7F6D28AF7A9
annotation: SIP16FE9F7D5E94B359
annotation: SIP3E881BE2528E4F88
annotation: SIPCEE9CFA9C2A34965
annotation: SIPE1B2758CA1D51AE4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0004055
classified with: GO_0005524
classified with: GO_0006526
sequence: Q6L1N7-1
proteome: Chromosome

Q6L1N7-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG00112
type: Resource
database: eggNOG
comment: Archaea

cd01999
type: Resource
database: CDD
comment: Argininosuccinate_Synthase
signature sequence match: CDD cd01999 match 1

http://purl.uniprot.org/gene3d/3.90.1260.10
type: Resource
database: Gene3D
comment: Argininosuccinate synthetase, chain A, domain 2
signature sequence match: Gene3D 3.90.1260.10 match 1

http://purl.uniprot.org/gene3d/3.40.50.620
type: Resource
database: Gene3D
comment: HUPs
signature sequence match: Gene3D 3.40.50.620 match 1
signature sequence match: Gene3D 3.40.50.620 match 2

MF_00005
type: Resource
database: HAMAP
comment: Arg_succ_synth_type1
signature sequence match: HAMAP MF 00005 match 1

IPR001518
type: Resource
database: InterPro
comment: Arginosuc_synth

IPR018223
type: Resource
database: InterPro
comment: Arginosuc_synth_CS

IPR023434
type: Resource
database: InterPro
comment: Arginosuc_synth_type_1_subfam

IPR024074
type: Resource
database: InterPro
comment: AS_cat/multimer_dom_body

IPR014729
type: Resource
database: InterPro
comment: Rossmann-like_a/b/a_fold

PTHR11587
type: Resource
database: PANTHER
comment: ARGININOSUCCINATE SYNTHASE
signature sequence match: PANTHER PTHR11587 match 1

PTHR11587:SF2
type: Resource
database: PANTHER
comment: ARGININOSUCCINATE SYNTHASE
signature sequence match: PANTHER PTHR11587:SF2 match 1

PF00764
type: Resource
database: Pfam
comment: Arginosuc_synth
signature sequence match: Pfam PF00764 match 1

SSF52402
type: Resource
database: SUPFAM
comment: Adenine nucleotide alpha hydrolases-like
signature sequence match: SUPFAM SSF52402 match 1

SSF69864
type: Resource
database: SUPFAM
comment: Argininosuccinate synthetase, C-terminal domain
signature sequence match: SUPFAM SSF69864 match 1

TIGR00032
type: Resource
database: TIGRFAMs
comment: argG
signature sequence match: TIGRFAMs TIGR00032 match 1

PS00564
type: Resource
database: PROSITE
comment: ARGININOSUCCIN_SYN_1
signature sequence match: PROSITE PS00564 match 1

PS00565
type: Resource
database: PROSITE
comment: ARGININOSUCCIN_SYN_2
signature sequence match: PROSITE PS00565 match 1

SIP61A4B13E979BBE2A
type: Structured Name
full name: Argininosuccinate synthase
ec name: 6.3.4.5

SIPA9120089B7B542D8
type: Structured Name
full name: Citrulline--aspartate ligase

argG
type: Gene
locus name: PTO0530

SIPD103A413C01438BF
type: Subunit Annotation
comment: Homotetramer.

SIP9421A434AA62D790
type: Similarity Annotation
comment: Belongs to the argininosuccinate synthase family. Type 1 subfamily.

PRO_0000148682
type: Chain Annotation
comment: Argininosuccinate synthase
mass: 44509
range: 22859173986187054tt1tt395

22859173986187054tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L1N7-1

22859173986187054tt395
type: Position
type: ExactPosition
position: 395
reference: Q6L1N7-1

22859173986187054tt7
type: Position
type: ExactPosition
position: 7
reference: Q6L1N7-1

22859173986187054tt15
type: Position
type: ExactPosition
position: 15
reference: Q6L1N7-1

22859173986187054tt83
type: Position
type: ExactPosition
position: 83
reference: Q6L1N7-1

22859173986187054tt113
type: Position
type: ExactPosition
position: 113
reference: Q6L1N7-1

22859173986187054tt115
type: Position
type: ExactPosition
position: 115
reference: Q6L1N7-1

22859173986187054tt119
type: Position
type: ExactPosition
position: 119
reference: Q6L1N7-1

22859173986187054tt120
type: Position
type: ExactPosition
position: 120
reference: Q6L1N7-1

22859173986187054tt123
type: Position
type: ExactPosition
position: 123
reference: Q6L1N7-1

22859173986187054tt169
type: Position
type: ExactPosition
position: 169
reference: Q6L1N7-1

22859173986187054tt178
type: Position
type: ExactPosition
position: 178
reference: Q6L1N7-1

22859173986187054tt253
type: Position
type: ExactPosition
position: 253
reference: Q6L1N7-1

22859173986187054tt265
type: Position
type: ExactPosition
position: 265
reference: Q6L1N7-1

Q6L1N7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 44509
value: MEKALLLYSGGLDTSVMVRWIKEKMNMDVVTLTLDIGNSDLEEIKEKALKLGAIDAITLDVKKEFADNYISREIHANGLYGEYPLSTALARPLMAEKAVSVANENDIKFIAHGSTGKGNDQVRFEVSINALDNNIKVIAPVREWNMTRADELEYAKMNNIYVKSDGKYSVDENIWGRSIEGSSIENINEPVNDDAFEWVTPPQYCGSGEPVSIEFYKGLPSSLNGKSMDLLSIIKNLNIIAGRNGIGIINMIESRLIGLKSHEVYECPAASVILKAHKYLENLILNKNELSVKNYIDNFWSNMVYNGLWFDPSMEHMNQFEKSSNQYITGSVNLRLYRGNMILEGIESPYSLYDYNTINYETGVFDQGSSKGFIDIYKNETVRSNRVKKALTVIH

http://purl.uniprot.org/uniprot/Q6L1N7#attribution-EC13E954DE6CEC253F15522F522CC250
manual: true
evidence: ECO_0000255
source: MF_00005

Q9HKF1
type: Protein
reviewed: true
created: 2001-04-27
modified: 2023-02-22
version: 121
mnemonic: ASSY_THEAC
citation: http://purl.uniprot.org/citations/11029001
conflicting sequence: SIPF5438FA6686187F4
recommended name: SIP61A4B13E979BBE2A
alternative name: SIPA9120089B7B542D8
enzyme: http://purl.uniprot.org/enzyme/6.3.4.5
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP6378FC8AD4A8EBDD
annotation: SIP7D5AFF0FB2D1943C
annotation: SIPF86C1DE6030F11CE
annotation: SIPA13AF2FAECEC7B74
annotation: SIP1FD7F112E673E64E
annotation: SIPA22A86215BF121A5
annotation: PRO_0000148688
annotation: SIP38A95535438D8B93
annotation: SIP2B1D92B3E95FEA2A
annotation: SIP0F0E19B40902D582
annotation: SIP19694779575A4BFE
annotation: SIPD7905A505AAC2151
annotation: SIPDF308668FDBDBB18
annotation: SIPEB9FFCD9BAD24395
annotation: SIPD28E67D380126433
annotation: SIP8978E023574278D3
annotation: SIP33287F27C3F0EE34
annotation: SIP4CA023793597BDD2
annotation: SIP70E031E2E993D8BC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0004055
classified with: GO_0005524
classified with: GO_0006526
sequence: Q9HKF1-1
proteome: Chromosome

Q9HKF1-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

EMBL CAC11788.1
comment: Different initiation.

SIP61A4B13E979BBE2A
type: Structured Name
full name: Argininosuccinate synthase
ec name: 6.3.4.5

SIPA9120089B7B542D8
type: Structured Name
full name: Citrulline--aspartate ligase

argG
type: Gene
locus name: Ta0650

SIPF86C1DE6030F11CE
type: Subunit Annotation
comment: Homotetramer.

SIP1FD7F112E673E64E
type: Similarity Annotation
comment: Belongs to the argininosuccinate synthase family. Type 1 subfamily.

PRO_0000148688
type: Chain Annotation
comment: Argininosuccinate synthase
mass: 44813
range: 22862455776882990tt1tt402

22862455776882990tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKF1-1

22862455776882990tt402
type: Position
type: ExactPosition
position: 402
reference: Q9HKF1-1

22862455776882990tt7
type: Position
type: ExactPosition
position: 7
reference: Q9HKF1-1

22862455776882990tt15
type: Position
type: ExactPosition
position: 15
reference: Q9HKF1-1

22862455776882990tt83
type: Position
type: ExactPosition
position: 83
reference: Q9HKF1-1

22862455776882990tt113
type: Position
type: ExactPosition
position: 113
reference: Q9HKF1-1

22862455776882990tt115
type: Position
type: ExactPosition
position: 115
reference: Q9HKF1-1

22862455776882990tt119
type: Position
type: ExactPosition
position: 119
reference: Q9HKF1-1

22862455776882990tt120
type: Position
type: ExactPosition
position: 120
reference: Q9HKF1-1

22862455776882990tt123
type: Position
type: ExactPosition
position: 123
reference: Q9HKF1-1

22862455776882990tt169
type: Position
type: ExactPosition
position: 169
reference: Q9HKF1-1

22862455776882990tt178
type: Position
type: ExactPosition
position: 178
reference: Q9HKF1-1

22862455776882990tt253
type: Position
type: ExactPosition
position: 253
reference: Q9HKF1-1

22862455776882990tt265
type: Position
type: ExactPosition
position: 265
reference: Q9HKF1-1

Q9HKF1-1
type: Simple Sequence
modified: 2006-12-12
version: 2
mass: 44813
value: MDKALLLYSGGLDTSVMIKWIQENLSMDVATLTLNVGNSDLVAIEEKARMLGADPVFVHDAKDEFAEKFIAKSIMANGSYEGYPLSTALARPLMAEKAVKYAQKIGAKYIVHGSTGRGNDQVRFEVSIRALDPSMQVLVPVREWNMMRKDEVEYAKTHGIPVKLDGKYSIDENIWGRSVEGPDLEDIGKGVPEDVYEWVVPPWKANAEHTLKIAFDGGIPSEIDGEKMKLADLIVFLNTLAGSSGIGLIDHMENRVVGLKSHEVYECPAATVITHAHRYLESLILNRNEAEVKMNMDWQFAKFVYGGLWHDPVMNAVNAAEAEFNRDISGEIKIRMSHGIMYIEGAWGNSFLYSKDLINYSSMAFDQRASKGFIDIYGNATVHSHNRNPKMVKEVQGSSVEF

http://purl.uniprot.org/uniprot/Q9HKF1#attribution-EC13E954DE6CEC253F15522F522CC250
manual: true
evidence: ECO_0000255
source: MF_00005

http://purl.uniprot.org/uniprot/Q9HKF1#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q97A55
type: Protein
reviewed: true
created: 2003-04-23
modified: 2023-02-22
version: 113
mnemonic: ASSY_THEVO
citation: http://purl.uniprot.org/citations/11121031
conflicting sequence: SIP07A7B195CB3A1EBC
recommended name: SIP61A4B13E979BBE2A
alternative name: SIPA9120089B7B542D8
enzyme: http://purl.uniprot.org/enzyme/6.3.4.5
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPFBF854695D626A1B
annotation: SIP8BEF960F0ECDEBE6
annotation: SIPA555C2869964951F
annotation: SIP4444F006A7D60150
annotation: SIP9911DCA862EFC8C3
annotation: SIPB684B7AE439D18BC
annotation: PRO_0000148689
annotation: SIP07A77B9D7851FCD3
annotation: SIP1A2E134EE6464BB4
annotation: SIP8CF624D20D4723FF
annotation: SIPB5C3CA1E4F1F43A0
annotation: SIPE7C43F690E5CDDBD
annotation: SIP90090BC598B84CB1
annotation: SIPEEDD2EEBC692EAE1
annotation: SIPA95FA02E2A04AA92
annotation: SIP6742C3301657071C
annotation: SIPB840ACC4136D9C8B
annotation: SIP44A2AB9E26AFE646
annotation: SIPC2E1DC86DCD55A90
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: GO_0005737
classified with: GO_0004055
classified with: GO_0005524
classified with: GO_0006526
sequence: Q97A55-1
proteome: Chromosome

Q97A55-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

EMBL BAB60097.1
comment: Sequence problems.

SIP61A4B13E979BBE2A
type: Structured Name
full name: Argininosuccinate synthase
ec name: 6.3.4.5

SIPA9120089B7B542D8
type: Structured Name
full name: Citrulline--aspartate ligase

argG
type: Gene
locus name: TV0955
orf name: TVG0979194

SIPA555C2869964951F
type: Subunit Annotation
comment: Homotetramer.

SIP9911DCA862EFC8C3
type: Similarity Annotation
comment: Belongs to the argininosuccinate synthase family. Type 1 subfamily.

SIPB684B7AE439D18BC
type: Erroneous Termination Annotation
comment: Truncated C-terminus.
conflicting sequence: SIP07A7B195CB3A1EBC

PRO_0000148689
type: Chain Annotation
comment: Argininosuccinate synthase
mass: 44342
range: 22862382593553710tt1tt397

22862382593553710tt1
type: Position
type: ExactPosition
position: 1
reference: Q97A55-1

22862382593553710tt397
type: Position
type: ExactPosition
position: 397
reference: Q97A55-1

22862382593553710tt7
type: Position
type: ExactPosition
position: 7
reference: Q97A55-1

22862382593553710tt15
type: Position
type: ExactPosition
position: 15
reference: Q97A55-1

22862382593553710tt83
type: Position
type: ExactPosition
position: 83
reference: Q97A55-1

22862382593553710tt113
type: Position
type: ExactPosition
position: 113
reference: Q97A55-1

22862382593553710tt115
type: Position
type: ExactPosition
position: 115
reference: Q97A55-1

22862382593553710tt119
type: Position
type: ExactPosition
position: 119
reference: Q97A55-1

22862382593553710tt120
type: Position
type: ExactPosition
position: 120
reference: Q97A55-1

22862382593553710tt123
type: Position
type: ExactPosition
position: 123
reference: Q97A55-1

22862382593553710tt169
type: Position
type: ExactPosition
position: 169
reference: Q97A55-1

22862382593553710tt178
type: Position
type: ExactPosition
position: 178
reference: Q97A55-1

22862382593553710tt253
type: Position
type: ExactPosition
position: 253
reference: Q97A55-1

22862382593553710tt265
type: Position
type: ExactPosition
position: 265
reference: Q97A55-1

Q97A55-1
type: Simple Sequence
modified: 2007-02-20
version: 3
mass: 44342
value: MKELLLLYSGGLDTSVMIKWMNENLGYDVSTLTLDIGNNDLKSIREKAEAIGAVETFVEDVKQEFSYEYISKSILANGSYEGYPLSTALARPLMAKKAVELAEKHGFEAIAHGSTGRGNDQVRFELGIKALNPSLEMLAPVRDWNMLRSEEIEYAKKNNIIVPSDGKYSVDENLWGRSIEGSEIENMSLPVPEDAYEWLVPPWEAGPGEVIKLEFSNGLPVAINDSDFELQNLIANLNIIGGRNSIGLIDHVEDRITGIKSREVYECPAAEIITYAHGYLESLILNKHEISIKSFLDSKFSQFVYNGLWYDPAMKPLIAGEEILNSEINGSISLKLYKGKIYFNGSKGANFSYNSNVANYSTYEFDQKSSKGFIDIFKNDTVYSILARQKAKEEALS

http://purl.uniprot.org/uniprot/Q97A55#attribution-EC13E954DE6CEC253F15522F522CC250
manual: true
evidence: ECO_0000255
source: MF_00005

http://purl.uniprot.org/uniprot/Q97A55#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6L1W3
type: Protein
reviewed: true
created: 2006-07-25
modified: 2023-05-03
version: 97
mnemonic: ATGT_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP9AA0A67C1CC27F6F
alternative name: SIPDF02F41DC9D1950C
alternative name: SIP65E5A587C3AB5E41
enzyme: http://purl.uniprot.org/enzyme/2.4.2.48
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIPEA234044AB35375B
annotation: SIP7192F3F23723378A
annotation: SIP56B44FEC4EC48EFE
annotation: SIPF8E5A56D2617EEBD
annotation: SIP1ACE8B085DB47D8F
annotation: PRO_0000247880
annotation: SIPA48D84AE56D78888
annotation: SIPAA2921D5AC430FD5
annotation: SIP7B7CD3AC28587D77
annotation: SIP539741227D1D877D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/328
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/819
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0046872
classified with: GO_0016763
classified with: GO_0003723
classified with: GO_0006400
sequence: Q6L1W3-1
proteome: Chromosome

Q6L1W3-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG00989
type: Resource
database: eggNOG
comment: Archaea

arCOG00991
type: Resource
database: eggNOG
comment: Archaea

cd21149
type: Resource
database: CDD
comment: PUA_archaeosine_TGT
signature sequence match: CDD cd21149 match 1

http://purl.uniprot.org/gene3d/3.10.450.90
type: Resource
database: Gene3D
comment: ArcTGT, C2 domain
signature sequence match: Gene3D 3.10.450.90 match 1

MF_01634
type: Resource
database: HAMAP
comment: TgtA_arch
signature sequence match: HAMAP MF 01634 match 1

IPR029402
type: Resource
database: InterPro
comment: TGT_C2

IPR038250
type: Resource
database: InterPro
comment: TGT_C2_sf

IPR004804
type: Resource
database: InterPro
comment: TgtA

IPR002616
type: Resource
database: InterPro
comment: tRNA_ribo_trans-like

PTHR46499
type: Resource
database: PANTHER
comment: QUEUINE TRNA-RIBOSYLTRANSFERASE
signature sequence match: PANTHER PTHR46499 match 1

PTHR46499:SF1
type: Resource
database: PANTHER
comment: QUEUINE TRNA-RIBOSYLTRANSFERASE
signature sequence match: PANTHER PTHR46499:SF1 match 1

PF01702
type: Resource
database: Pfam
comment: TGT
signature sequence match: Pfam PF01702 match 1

PF14810
type: Resource
database: Pfam
comment: TGT_C2
signature sequence match: Pfam PF14810 match 1

SM00359
type: Resource
database: SMART
comment: PUA
signature sequence match: SMART SM00359 match 1

TIGR00432
type: Resource
database: TIGRFAMs
comment: arcsn_tRNA_tgt
signature sequence match: TIGRFAMs TIGR00432 match 1

TIGR00449
type: Resource
database: TIGRFAMs
comment: tgt_general
signature sequence match: TIGRFAMs TIGR00449 match 1

SIP9AA0A67C1CC27F6F
type: Structured Name
full name: tRNA-guanine(15) transglycosylase
ec name: 2.4.2.48

SIPDF02F41DC9D1950C
type: Structured Name
full name: 7-cyano-7-deazaguanine tRNA-ribosyltransferase

SIP65E5A587C3AB5E41
type: Structured Name
full name: Archaeal tRNA-guanine transglycosylase

tgtA
type: Gene
locus name: PTO0454

SIPEA234044AB35375B
type: Function Annotation
comment: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

SIP56B44FEC4EC48EFE
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP1ACE8B085DB47D8F
type: Similarity Annotation
comment: Belongs to the archaeosine tRNA-ribosyltransferase family.

PRO_0000247880
type: Chain Annotation
comment: tRNA-guanine(15) transglycosylase
mass: 72063
range: 22859173986775854tt1tt625

22859173986775854tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L1W3-1

22859173986775854tt625
type: Position
type: ExactPosition
position: 625
reference: Q6L1W3-1

SIPA48D84AE56D78888
type: Domain Extent Annotation
comment: PUA
range: 22859173986775854tt546tt621

22859173986775854tt546
type: Position
type: ExactPosition
position: 546
reference: Q6L1W3-1

22859173986775854tt621
type: Position
type: ExactPosition
position: 621
reference: Q6L1W3-1

SIPAA2921D5AC430FD5
type: Active Site Annotation
comment: Nucleophile
range: 22859173986775854tt86tt86

22859173986775854tt86
type: Position
type: ExactPosition
position: 86
reference: Q6L1W3-1

22859173986775854tt121
type: Position
type: ExactPosition
position: 121
reference: Q6L1W3-1

22859173986775854tt184
type: Position
type: ExactPosition
position: 184
reference: Q6L1W3-1

substrate

Q6L1W3-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 72063
value: MEILFRENLARIARFKTPHGEIETPTVMPVINPNLNFLDESTLRSYGVQAVITNSYIIKRNQRLNEDALRHGLHSLIKFSGPIMTDSGTFQSHVYGDIEYSNKEIVDFQKAIGSDIITILDVFTEPDESYNSARSKVIETYKRLKEIDFEDKIIAGPVQGSIYPDLRRLSAYLMSDALYLPIGGVVPLLESYRYSDLVKIIFNSKVSSDFSRPVHLFGGGHPMFFAFAVMLGVDLFDSASYIKYAKDNRLLYSEGTRALNDIREFPEWSPIHGKYTPQELLHEESEKRTRMLALHNLKSIFIEINEIKERIYENTLYNYVEEKARSHPALFKAFMSMINYDTSDYSPLSYKSPFFYYDKTSLNHPIIKRIMKFTENYISNSRHTLIISSKYWRPGVKNENVIKNIVECTDFNLLVSWNGIYIPLFLEDSYPVQQLVSSGLNDKKLEEDYLKRLKSINNDIEFYEGEHYDKRLRDYDTEKINTIAMFQFNINERFFDKSNIIKSKSTGHIRNIIEDNNIIATMRNDGYLTLSIKGAYRLLSMKPWPGLRVVVDDESGRFNANGYNVFFKFIKSFDTGIIPGNETLVVSEDDDLYAVGKAAVSGIEMYYYKSGVAVKVHEGVNKKAA

http://purl.uniprot.org/uniprot/Q6L1W3#attribution-7EF869E371A598699178AE567CAAA2E8
manual: true
evidence: ECO_0000255
source: MF_01634

Q9HI54
type: Protein
reviewed: true
created: 2006-07-25
modified: 2023-05-03
version: 107
mnemonic: ATGT_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP9AA0A67C1CC27F6F
alternative name: SIPDF02F41DC9D1950C
alternative name: SIP65E5A587C3AB5E41
enzyme: http://purl.uniprot.org/enzyme/2.4.2.48
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPB50372A600D64265
annotation: SIP25D8C744B0C627E3
annotation: SIPB96A4A4238B169C2
annotation: SIP72CF62206DE17C31
annotation: SIPCA09946EF7DBA45A
annotation: PRO_0000247887
annotation: SIP914ABB0FB9A96351
annotation: SIP9C4177BB5141418C
annotation: SIP38EA7F6EAE237AE4
annotation: SIPC49715203D534F4E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/328
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/819
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0046872
classified with: GO_0016763
classified with: GO_0003723
classified with: GO_0006400
sequence: Q9HI54-1
proteome: Chromosome

Q9HI54-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

http://purl.uniprot.org/brenda/2.4.2.48
type: Resource
database: BRENDA
comment: 6324

IPR004521
type: Resource
database: InterPro
comment: Uncharacterised_CHP00451

TIGR00451
type: Resource
database: TIGRFAMs
comment: unchar_dom_2
signature sequence match: TIGRFAMs TIGR00451 match 1

SIP9AA0A67C1CC27F6F
type: Structured Name
full name: tRNA-guanine(15) transglycosylase
ec name: 2.4.2.48

SIPDF02F41DC9D1950C
type: Structured Name
full name: 7-cyano-7-deazaguanine tRNA-ribosyltransferase

SIP65E5A587C3AB5E41
type: Structured Name
full name: Archaeal tRNA-guanine transglycosylase

tgtA
type: Gene
locus name: Ta1493

SIPB50372A600D64265
type: Function Annotation
comment: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

SIPB96A4A4238B169C2
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIPCA09946EF7DBA45A
type: Similarity Annotation
comment: Belongs to the archaeosine tRNA-ribosyltransferase family.

PRO_0000247887
type: Chain Annotation
comment: tRNA-guanine(15) transglycosylase
mass: 71910
range: 22862455742215214tt1tt632

22862455742215214tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HI54-1

22862455742215214tt632
type: Position
type: ExactPosition
position: 632
reference: Q9HI54-1

SIP914ABB0FB9A96351
type: Domain Extent Annotation
comment: PUA
range: 22862455742215214tt553tt628

22862455742215214tt553
type: Position
type: ExactPosition
position: 553
reference: Q9HI54-1

22862455742215214tt628
type: Position
type: ExactPosition
position: 628
reference: Q9HI54-1

SIP9C4177BB5141418C
type: Active Site Annotation
comment: Nucleophile
range: 22862455742215214tt86tt86

22862455742215214tt86
type: Position
type: ExactPosition
position: 86
reference: Q9HI54-1

22862455742215214tt121
type: Position
type: ExactPosition
position: 121
reference: Q9HI54-1

22862455742215214tt186
type: Position
type: ExactPosition
position: 186
reference: Q9HI54-1

substrate

Q9HI54-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 71910
value: MKIEERDGLARIAKFETPHGPIETPTVLPVINPNIMNITPQEMKPLGLQGIITNSYIILRTPELRERALREGLHSLIGYDGPIMTDSGTFQSYVYGSIEFNNREVVDFQRRIGSDISTILDVFTTPGTPKPEAEKAVIETYNRMLEVNDEEGIIAGPVQGGVYPDLRQKSAELMNSTNAGYHPIGGVVPLLETYDYSTLVDIIINSKINLSFNKPVHLFGGGHPMFFAFSVYLGVDLFDSASYIKYAKDDRLIYPDGTRDLARITELPQWSPLYDRYTVKEIRDLDKERRSLEIARHNLKAIFMEISEIKERIYEEGLAQYVAQKARSHPSLMKAYSRIMSYSNILEKYEDLSKKTAYFFYDSFSTRNPYVSRINRFTESYLSSNKKDTYAFTYRAWNPGYTNSEFVRDVYQKIDCNALISWSGTFVPAELENTYPIEQTVSSGFEPDPDFSRAKDLIAPFRVDMYKGEKFEGEQVRSFNLNKIRMVADYQFGSGVGRMIFRDDVRINVSKTGRIRGILSKEGRQIATMRNDGFFTLTYYGASLIHSQLKPPAMRVTVSKESAEYNAKGYSVFFKFILGSDENIIAKNDVLVVDEDDVLAAVGKAMVSGRELREYTEGIAVKVHEGRDQSEK

http://purl.uniprot.org/uniprot/Q9HI54#attribution-7EF869E371A598699178AE567CAAA2E8
manual: true
evidence: ECO_0000255
source: MF_01634

Q977Z3
type: Protein
reviewed: true
created: 2006-07-25
modified: 2023-05-03
version: 107
mnemonic: ATGT_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP9AA0A67C1CC27F6F
alternative name: SIPDF02F41DC9D1950C
alternative name: SIP65E5A587C3AB5E41
enzyme: http://purl.uniprot.org/enzyme/2.4.2.48
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPA29FF18723D8E8DA
annotation: SIPBCA72FC1B9FD37CD
annotation: SIP56DE271F1F2D3DBF
annotation: SIP6C7B17751DAEEBB4
annotation: SIPFACD7CD515D7CD2D
annotation: PRO_0000247888
annotation: SIPDBA46AFE1DCAF0A6
annotation: SIPA8F08E4B02C7E1D8
annotation: SIP83CB7D7E0836A487
annotation: SIP94F89D917872D264
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/328
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/819
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0046872
classified with: GO_0016763
classified with: GO_0003723
classified with: GO_0006400
sequence: Q977Z3-1
proteome: Chromosome

Q977Z3-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP9AA0A67C1CC27F6F
type: Structured Name
full name: tRNA-guanine(15) transglycosylase
ec name: 2.4.2.48

SIPDF02F41DC9D1950C
type: Structured Name
full name: 7-cyano-7-deazaguanine tRNA-ribosyltransferase

SIP65E5A587C3AB5E41
type: Structured Name
full name: Archaeal tRNA-guanine transglycosylase

tgtA
type: Gene
locus name: TV1524
orf name: TVG1580555

SIPA29FF18723D8E8DA
type: Function Annotation
comment: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

SIP56DE271F1F2D3DBF
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIPFACD7CD515D7CD2D
type: Similarity Annotation
comment: Belongs to the archaeosine tRNA-ribosyltransferase family.

PRO_0000247888
type: Chain Annotation
comment: tRNA-guanine(15) transglycosylase
mass: 71957
range: 22862382428205870tt1tt632

22862382428205870tt1
type: Position
type: ExactPosition
position: 1
reference: Q977Z3-1

22862382428205870tt632
type: Position
type: ExactPosition
position: 632
reference: Q977Z3-1

SIPDBA46AFE1DCAF0A6
type: Domain Extent Annotation
comment: PUA
range: 22862382428205870tt553tt628

22862382428205870tt553
type: Position
type: ExactPosition
position: 553
reference: Q977Z3-1

22862382428205870tt628
type: Position
type: ExactPosition
position: 628
reference: Q977Z3-1

SIPA8F08E4B02C7E1D8
type: Active Site Annotation
comment: Nucleophile
range: 22862382428205870tt86tt86

22862382428205870tt86
type: Position
type: ExactPosition
position: 86
reference: Q977Z3-1

22862382428205870tt121
type: Position
type: ExactPosition
position: 121
reference: Q977Z3-1

22862382428205870tt186
type: Position
type: ExactPosition
position: 186
reference: Q977Z3-1

substrate

Q977Z3-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 71957
value: MEIRERDGLARIARFDTPHGTIETPTVLPVINPNIMDITPEEMKKYGVHGVITNSYIILRNDRLREEAEKYGVHSLIGYDGPVMTDSGTFQSYVYGSVEFNNRQVVEFQKTIGSDILTILDIFTTPSSSRQEVENAITETYRRMLEVNDAGGMIAGPIQGGIYPDLRKRSAELMNSTNASYLPIGGVVPLLESYEYDKLVDIILNSKLNVSFGKPIHLFGGGHPMFFAFAVYLGVDLFDSASYVKYAKDDRLIYPDGTRDLARIIEIPEWSPLFDKYTVKELKELPKEQRSVELSRHNLKAIFMEISEIRERIYEESMDQYLAQKAKSHPSLLKAYVKVMQYSKMLEKYQDLFKKAAYFFYDSFSTKNTYVARLEKFTSKYLTSKKKETYVFSRKDWLPGYTNLNFVRDVYERTECNALIPWSGIMVPAELENTYPIEQTVSSGLEPDPDVSAISESISPFDIRVYKGESVDSDKIRSFDLEKIRTIADYQFGYGIGKDFFKDDVRIFKSKTGRIRGVFDKGNKLIATLRNDGFFTLTFHGATLLYNVSKSPNLRVFVKNESAEYNAKGYSVFFKFILDADPDIIAKNETLVVNENGELVAVGKATVSGKELREYSDGIAVKIHEGRDQSAK

http://purl.uniprot.org/uniprot/Q977Z3#attribution-7EF869E371A598699178AE567CAAA2E8
manual: true
evidence: ECO_0000255
source: MF_01634

Q6L0F3
type: Protein
reviewed: true
created: 2007-11-13
modified: 2023-02-22
version: 93
mnemonic: CAPPA_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIPB51A91AD371B7CB1
enzyme: http://purl.uniprot.org/enzyme/4.1.1.31
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIPC723D53E16997BF7
annotation: SIPD8789B0AD6056EF0
annotation: SIP71E1A42CC12B8D41
annotation: SIP8255F9E431A4A3C1
annotation: SIPB3C250E376291AE8
annotation: PRO_0000309606
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/120
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0000287
classified with: GO_0008964
classified with: GO_0015977
classified with: GO_0006107
classified with: GO_0006099
sequence: Q6L0F3-1
proteome: Chromosome

Q6L0F3-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG04435
type: Resource
database: eggNOG
comment: Archaea

MF_01904
type: Resource
database: HAMAP
comment: PEPcase_type2
signature sequence match: HAMAP MF 01904 match 1

IPR007566
type: Resource
database: InterPro
comment: PEP_COase_arc-type

IPR015813
type: Resource
database: InterPro
comment: Pyrv/PenolPyrv_Kinase-like_dom

PF14010
type: Resource
database: Pfam
comment: PEPcase_2
signature sequence match: Pfam PF14010 match 1

PIRSF006677
type: Resource
database: PIRSF
comment: UCP006677
signature sequence match: PIRSF PIRSF006677 match 1

SSF51621
type: Resource
database: SUPFAM
comment: Phosphoenolpyruvate/pyruvate domain
signature sequence match: SUPFAM SSF51621 match 1

TIGR02751
type: Resource
database: TIGRFAMs
comment: PEPCase_arch
signature sequence match: TIGRFAMs TIGR02751 match 1

SIPB51A91AD371B7CB1
type: Structured Name
full name: Phosphoenolpyruvate carboxylase
short name: PEPC
short name: PEPCase
ec name: 4.1.1.31

ppcA
type: Gene
locus name: PTO0964

SIPC723D53E16997BF7
type: Function Annotation
comment: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

SIP8255F9E431A4A3C1
type: Subunit Annotation
comment: Homotetramer.

SIPB3C250E376291AE8
type: Similarity Annotation
comment: Belongs to the PEPCase type 2 family.

PRO_0000309606
type: Chain Annotation
comment: Phosphoenolpyruvate carboxylase
mass: 58714
range: 22859173968884526tt1tt508

22859173968884526tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L0F3-1

22859173968884526tt508
type: Position
type: ExactPosition
position: 508
reference: Q6L0F3-1

Q6L0F3-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 58714
value: MAIAMIPKTMSTQHPDNAKMPAWASEKSMIRNDDEVEEAYQCYTIGIKEVMWDAEGKDVDTHVLRKLISKNHEFFEKNVLGSDIFLTYRVPNPAIEGTERKVLTETLESIPVNYDVFNTVYKRDIPPIFEVILPFTTSSKDLLNIAKYYEKAVAARDEIELYDNVMVKNILGETKPKKINIIPLIEDKDSMFNIDGIVKNFARAVSAKKMRVFIARSDPAMNYGMIPAVLMSKYAASRLCKMNDDIENYPIVGVGSSTFRGRFSPENIEKSLYEYSNYYTFTLQSAFKYDYPQDSVKNSINIINRHERSFDYLEDYEEEIIKNAVNKYVINYQKIIEKLAPAINNITMYLPKRRSRKLHIGLFGYSRSTGNVTLPRAISFVGAMYSMGLPPEIIGISSLLNMKDDELDIIEKTYINLRSDIMESSSYLNYEVFDALKDVYKIDQETINMIKADVKYIENNYGIKSDLGYERERHNYLSSLMNLAFKNHDFENTRKYILDMALIRKFIG

http://purl.uniprot.org/uniprot/Q6L0F3#attribution-722BAA719696F0F2537D26C57719CB7F
manual: true
evidence: ECO_0000255
source: MF_01904

Q9HK16
type: Protein
reviewed: true
created: 2002-07-11
modified: 2023-02-22
version: 122
mnemonic: CARA_THEAC
citation: http://purl.uniprot.org/citations/11029001
conflicting sequence: SIPC439383AA29AC74F
recommended name: SIP1E2AAD5826F81973
alternative name: SIP5D1781685ADDA81F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.5
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPBA8FDDF90064822B
annotation: SIP992E1801B9D01790
annotation: SIPDED55E101BEF876C
annotation: SIP1B5F7A468825382A
annotation: SIP44DC159AF7E847E2
annotation: SIP265E610DD16E6199
annotation: PRO_0000112367
annotation: SIP7855B9B17F854AC0
annotation: SIP99DF8DDB1B377B11
annotation: SIPC0363B95D02045FF
annotation: SIP2FB71AA289194AB3
annotation: SIP6377F9D21B59E131
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/665
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0004088
classified with: GO_0006207
classified with: GO_0044205
classified with: GO_0006526
classified with: GO_0006541
sequence: Q9HK16-1
proteome: Chromosome

Q9HK16-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

EMBL CAC11923.1
comment: Different initiation.

arCOG00064
type: Resource
database: eggNOG
comment: Archaea

cd01744
type: Resource
database: CDD
comment: GATase1_CPSase
signature sequence match: CDD cd01744 match 1

http://purl.uniprot.org/gene3d/3.50.30.20
type: Resource
database: Gene3D
comment: Carbamoyl-phosphate synthase small subunit, N-terminal domain
signature sequence match: Gene3D 3.50.30.20 match 1

MF_01209
type: Resource
database: HAMAP
comment: CPSase_S_chain
signature sequence match: HAMAP MF 01209 match 1

IPR006274
type: Resource
database: InterPro
comment: CarbamoylP_synth_ssu

IPR002474
type: Resource
database: InterPro
comment: CarbamoylP_synth_ssu_N

IPR036480
type: Resource
database: InterPro
comment: CarbP_synth_ssu_N_sf

IPR029062
type: Resource
database: InterPro
comment: Class_I_gatase-like

IPR035686
type: Resource
database: InterPro
comment: CPSase_GATase1

IPR017926
type: Resource
database: InterPro
comment: GATASE

PTHR43418:SF7
type: Resource
database: PANTHER
comment: CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN
signature sequence match: PANTHER PTHR43418:SF7 match 1

PTHR43418
type: Resource
database: PANTHER
comment: MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED
signature sequence match: PANTHER PTHR43418 match 1

PF00988
type: Resource
database: Pfam
comment: CPSase_sm_chain
signature sequence match: Pfam PF00988 match 1

PF00117
type: Resource
database: Pfam
comment: GATase
signature sequence match: Pfam PF00117 match 1

PR00097
type: Resource
database: PRINTS
comment: ANTSNTHASEII

PR00099
type: Resource
database: PRINTS
comment: CPSGATASE

PR00096
type: Resource
database: PRINTS
comment: GATASE

SM01097
type: Resource
database: SMART
comment: CPSase_sm_chain
signature sequence match: SMART SM01097 match 1

SSF52021
type: Resource
database: SUPFAM
comment: Carbamoyl phosphate synthetase, small subunit N-terminal domain
signature sequence match: SUPFAM SSF52021 match 1

SSF52317
type: Resource
database: SUPFAM
comment: Class I glutamine amidotransferase-like
signature sequence match: SUPFAM SSF52317 match 1

TIGR01368
type: Resource
database: TIGRFAMs
comment: CPSaseIIsmall
signature sequence match: TIGRFAMs TIGR01368 match 1

PS51273
type: Resource
database: PROSITE
comment: GATASE_TYPE_1
signature sequence match: PROSITE PS51273 match 1

SIP1E2AAD5826F81973
type: Structured Name
full name: Carbamoyl-phosphate synthase small chain
ec name: 6.3.5.5

SIP5D1781685ADDA81F
type: Structured Name
full name: Carbamoyl-phosphate synthetase glutamine chain

carA
type: Gene
locus name: Ta0792

SIP1B5F7A468825382A
type: Subunit Annotation
comment: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

SIP44DC159AF7E847E2
type: Similarity Annotation
comment: Belongs to the CarA family.

PRO_0000112367
type: Chain Annotation
comment: Carbamoyl-phosphate synthase small chain
mass: 38645
range: 22862455775508014tt1tt348

22862455775508014tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HK16-1

22862455775508014tt348
type: Position
type: ExactPosition
position: 348
reference: Q9HK16-1

SIP7855B9B17F854AC0
type: Domain Extent Annotation
comment: Glutamine amidotransferase type-1
range: 22862455775508014tt168tt348

22862455775508014tt168
type: Position
type: ExactPosition
position: 168
reference: Q9HK16-1

SIP99DF8DDB1B377B11
type: Region Annotation
comment: CPSase
range: 22862455775508014tt1tt168

SIPC0363B95D02045FF
type: Active Site Annotation
comment: Nucleophile
range: 22862455775508014tt242tt242

22862455775508014tt242
type: Position
type: ExactPosition
position: 242
reference: Q9HK16-1

22862455775508014tt321
type: Position
type: ExactPosition
position: 321
reference: Q9HK16-1

22862455775508014tt323
type: Position
type: ExactPosition
position: 323
reference: Q9HK16-1

Q9HK16-1
type: Simple Sequence
modified: 2002-07-11
version: 2
mass: 38645
value: MKRYLITSDGTVIAGYGYGSPVTGYGELVFTTSMTGYLESMTDPSYVGQILVFASPTIANYELRKGVMESDRVKVSGIVTRDAHINMPAGTLGLDFDRFLRDEGIPAIDGVDTRLLVRKIRQGGVLRAYIADDPQGHSDFPDPMSENLVARAVDARGVKNIRGKGERRILFIDLGSKKTLRDMMLEHFSLIMASADSDLDAIDKYDAIFVSNGPGDPDHPSLRPVVNFLKRNIGVKPIFGICFGLQIIALAYGSKTYKMKFGHRGSNHAVTDGNRIYVTTHNHGYAVDPDTVRDFHVRERDINDGTIEMIEDGMMMAVQYHPEASPGPHDTRWFFSEMRRRTEDAAKG

http://purl.uniprot.org/uniprot/Q9HK16#attribution-10418227FB1BA43153D639116219F02D
manual: true
evidence: ECO_0000255
source: MF_01209

http://purl.uniprot.org/uniprot/Q9HK16#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q97AJ4
type: Protein
reviewed: true
created: 2002-07-11
modified: 2023-02-22
version: 127
mnemonic: CARA_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP1E2AAD5826F81973
alternative name: SIP5D1781685ADDA81F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.5
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP0695230C238D3637
annotation: SIPAE835CF5EAE8884F
annotation: SIPEB916846993A98FC
annotation: SIPDB4FCA211CCF72A5
annotation: SIPF961A86F72DE9A3B
annotation: PRO_0000112368
annotation: SIP31D6F5F7DB2125E5
annotation: SIPF8E49E9BF2672770
annotation: SIPEF91FE3ACC916635
annotation: SIPF98CB1134BBB1582
annotation: SIP4C76FA2DF4F84F51
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/665
classified with: GO_0005524
classified with: GO_0004088
classified with: GO_0006207
classified with: GO_0044205
classified with: GO_0006526
classified with: GO_0006541
sequence: Q97AJ4-1
proteome: Chromosome

Q97AJ4-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP1E2AAD5826F81973
type: Structured Name
full name: Carbamoyl-phosphate synthase small chain
ec name: 6.3.5.5

SIP5D1781685ADDA81F
type: Structured Name
full name: Carbamoyl-phosphate synthetase glutamine chain

carA
type: Gene
locus name: TV0816
orf name: TVG0820736

SIPDB4FCA211CCF72A5
type: Subunit Annotation
comment: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

SIPF961A86F72DE9A3B
type: Similarity Annotation
comment: Belongs to the CarA family.

PRO_0000112368
type: Chain Annotation
comment: Carbamoyl-phosphate synthase small chain
mass: 37923
range: 22862382594929710tt1tt345

22862382594929710tt1
type: Position
type: ExactPosition
position: 1
reference: Q97AJ4-1

22862382594929710tt345
type: Position
type: ExactPosition
position: 345
reference: Q97AJ4-1

SIP31D6F5F7DB2125E5
type: Domain Extent Annotation
comment: Glutamine amidotransferase type-1
range: 22862382594929710tt168tt345

22862382594929710tt168
type: Position
type: ExactPosition
position: 168
reference: Q97AJ4-1

SIPF8E49E9BF2672770
type: Region Annotation
comment: CPSase
range: 22862382594929710tt1tt168

SIPEF91FE3ACC916635
type: Active Site Annotation
comment: Nucleophile
range: 22862382594929710tt242tt242

22862382594929710tt242
type: Position
type: ExactPosition
position: 242
reference: Q97AJ4-1

22862382594929710tt321
type: Position
type: ExactPosition
position: 321
reference: Q97AJ4-1

22862382594929710tt323
type: Position
type: ExactPosition
position: 323
reference: Q97AJ4-1

Q97AJ4-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 37923
value: MKKYLVMEDGTVLSGQGYGSYKEAYGELVFTTSMTGYLETLTDPSYVGQMLVFASPTIANYALEMGKMESNGVKVSALITKDAHIELKKGGYGREFDEFLKEQGIPGIDGIDTRMLVRKIRANGVLRSYVVNDPSHSLDFPDPMNDDLVSKAVPHHDPVFVKGEEGGTVLFIDLGSKNTLKELMLQNFSLIVVDKQTNLDEIEGYDAIFVSNGPGDPSHPSLSNVIKFLSHNIGVKPLFGICFGLQAISLAYGAKTYKMKFGHRGSNHAVTDGTHSYVTTHNHGYAVDGSTVKDFKVIGWDANDGTVEIIEGDDMFAVQFHPEASPGPHDTRWFFGEMKRRIGYA

http://purl.uniprot.org/uniprot/Q97AJ4#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q97AJ4#attribution-BE2D5D43116646E6B62B6C00776AE244
manual: true
evidence: ECO_0000255
source: PRU00605

http://purl.uniprot.org/uniprot/Q97AJ4#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q9HK17
type: Protein
reviewed: true
created: 2002-08-02
modified: 2023-02-22
version: 129
mnemonic: CARB_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP70BCCA51962F43C3
alternative name: SIP628E9B800447372D
enzyme: http://purl.uniprot.org/enzyme/6.3.5.5
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP2DF7A5279E750092
annotation: SIP65D98DB487B0F2C5
annotation: SIPAC12E4762CB2DC00
annotation: SIP3ACD1DDA1319119F
annotation: SIP0BB5476F052B4219
annotation: SIP241D73EDA9EB0AFE
annotation: PRO_0000145086
annotation: SIP1923D68AA8C8E609
annotation: SIPEE0B973E82B33B8F
annotation: SIPF86E253786E5686C
annotation: SIP9187110836AAB153
annotation: SIP1EDA1AF1994F942A
annotation: SIPB98E766154343C5E
annotation: SIPE8A9CC9A666140D5
annotation: SIP55F0C78F7786A089
annotation: SIP3F06B1DFB31EE8A2
annotation: SIPCFB571D97AAEEC45
annotation: SIP07BFEFDA4DB8F99F
annotation: SIP976E8BCC8B236D55
annotation: SIPB531D29050E1D791
annotation: SIP5BCE93D1A186999B
annotation: SIP8E890DBBB9AADB76
annotation: SIP05BB07733F9711C7
annotation: SIP136ECCB1F0CF6894
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/665
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: GO_0005524
classified with: GO_0004088
classified with: GO_0046872
classified with: GO_0044205
classified with: GO_0006526
sequence: Q9HK17-1
proteome: Chromosome

Q9HK17-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG01594
type: Resource
database: eggNOG
comment: Archaea

cd01424
type: Resource
database: CDD
comment: MGS_CPS_II
signature sequence match: CDD cd01424 match 1

http://purl.uniprot.org/gene3d/3.30.1490.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, A domain
signature sequence match: Gene3D 3.30.1490.20 match 1
signature sequence match: Gene3D 3.30.1490.20 match 2

http://purl.uniprot.org/gene3d/3.30.470.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, B domain
signature sequence match: Gene3D 3.30.470.20 match 1
signature sequence match: Gene3D 3.30.470.20 match 2

http://purl.uniprot.org/gene3d/1.10.1030.10
type: Resource
database: Gene3D
comment: Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
signature sequence match: Gene3D 1.10.1030.10 match 1

http://purl.uniprot.org/gene3d/3.40.50.1380
type: Resource
database: Gene3D
comment: Methylglyoxal synthase-like domain
signature sequence match: Gene3D 3.40.50.1380 match 1

MF 01210 A
type: Resource
database: HAMAP
comment: CPSase_L_chain_A
signature sequence match: HAMAP MF 01210 A match 1

IPR011761
type: Resource
database: InterPro
comment: ATP-grasp

IPR013815
type: Resource
database: InterPro
comment: ATP_grasp_subdomain_1

IPR006275
type: Resource
database: InterPro
comment: CarbamoylP_synth_lsu

IPR005480
type: Resource
database: InterPro
comment: CarbamoylP_synth_lsu_oligo

IPR036897
type: Resource
database: InterPro
comment: CarbamoylP_synth_lsu_oligo_sf

IPR005479
type: Resource
database: InterPro
comment: CbamoylP_synth_lsu-like_ATP-bd

IPR005483
type: Resource
database: InterPro
comment: CbamoylP_synth_lsu_CPSase_dom

IPR011607
type: Resource
database: InterPro
comment: MGS-like_dom

IPR036914
type: Resource
database: InterPro
comment: MGS-like_dom_sf

IPR033937
type: Resource
database: InterPro
comment: MGS_CPS_CarB

IPR016185
type: Resource
database: InterPro
comment: PreATP-grasp_dom_sf

PTHR11405:SF5
type: Resource
database: PANTHER
comment: CAD PROTEIN
signature sequence match: PANTHER PTHR11405:SF5 match 1

PTHR11405
type: Resource
database: PANTHER
comment: CARBAMOYLTRANSFERASE FAMILY MEMBER
signature sequence match: PANTHER PTHR11405 match 1

PF02786
type: Resource
database: Pfam
comment: CPSase_L_D2
signature sequence match: Pfam PF02786 match 1
signature sequence match: Pfam PF02786 match 2

PF02787
type: Resource
database: Pfam
comment: CPSase_L_D3
signature sequence match: Pfam PF02787 match 1

PF02142
type: Resource
database: Pfam
comment: MGS
signature sequence match: Pfam PF02142 match 1

PR00098
type: Resource
database: PRINTS
comment: CPSASE

SM01096
type: Resource
database: SMART
comment: CPSase_L_D3
signature sequence match: SMART SM01096 match 1

SM00851
type: Resource
database: SMART
comment: MGS
signature sequence match: SMART SM00851 match 1

SSF48108
type: Resource
database: SUPFAM
comment: Carbamoyl phosphate synthetase, large subunit connection domain
signature sequence match: SUPFAM SSF48108 match 1

SSF56059
type: Resource
database: SUPFAM
comment: Glutathione synthetase ATP-binding domain-like
signature sequence match: SUPFAM SSF56059 match 1
signature sequence match: SUPFAM SSF56059 match 2

SSF52335
type: Resource
database: SUPFAM
comment: Methylglyoxal synthase-like
signature sequence match: SUPFAM SSF52335 match 1

SSF52440
type: Resource
database: SUPFAM
comment: PreATP-grasp domain
signature sequence match: SUPFAM SSF52440 match 1
signature sequence match: SUPFAM SSF52440 match 2

TIGR01369
type: Resource
database: TIGRFAMs
comment: CPSaseII_lrg
signature sequence match: TIGRFAMs TIGR01369 match 1

PS50975
type: Resource
database: PROSITE
comment: ATP_GRASP
signature sequence match: PROSITE PS50975 match 1
signature sequence match: PROSITE PS50975 match 2

PS00867
type: Resource
database: PROSITE
comment: CPSASE_2
signature sequence match: PROSITE PS00867 match 1
signature sequence match: PROSITE PS00867 match 2

PS51855
type: Resource
database: PROSITE
comment: MGS
signature sequence match: PROSITE PS51855 match 1

SIP70BCCA51962F43C3
type: Structured Name
full name: Carbamoyl-phosphate synthase large chain
ec name: 6.3.5.5

SIP628E9B800447372D
type: Structured Name
full name: Carbamoyl-phosphate synthetase ammonia chain

carB
type: Gene
locus name: Ta0791

SIP65D98DB487B0F2C5
type: Cofactor Annotation
comment: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
cofactor: CHEBI_18420
cofactor: CHEBI_29035

SIP0BB5476F052B4219
type: Subunit Annotation
comment: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

SIP241D73EDA9EB0AFE
type: Similarity Annotation
comment: Belongs to the CarB family.

PRO_0000145086
type: Chain Annotation
comment: Carbamoyl-phosphate synthase large chain
mass: 116852
range: 22862455775508270tt1tt1047

22862455775508270tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HK17-1

22862455775508270tt1047
type: Position
type: ExactPosition
position: 1047
reference: Q9HK17-1

SIP1923D68AA8C8E609
type: Domain Extent Annotation
comment: ATP-grasp 1
range: 22862455775508270tt133tt325

22862455775508270tt133
type: Position
type: ExactPosition
position: 133
reference: Q9HK17-1

22862455775508270tt325
type: Position
type: ExactPosition
position: 325
reference: Q9HK17-1

SIPEE0B973E82B33B8F
type: Domain Extent Annotation
comment: ATP-grasp 2
range: 22862455775508270tt665tt854

22862455775508270tt665
type: Position
type: ExactPosition
position: 665
reference: Q9HK17-1

22862455775508270tt854
type: Position
type: ExactPosition
position: 854
reference: Q9HK17-1

SIPF86E253786E5686C
type: Domain Extent Annotation
comment: MGS-like
range: 22862455775508270tt910tt1047

22862455775508270tt910
type: Position
type: ExactPosition
position: 910
reference: Q9HK17-1

SIP9187110836AAB153
type: Region Annotation
comment: Carboxyphosphate synthetic domain
range: 22862455775508270tt1tt398

22862455775508270tt398
type: Position
type: ExactPosition
position: 398
reference: Q9HK17-1

SIP1EDA1AF1994F942A
type: Region Annotation
comment: Oligomerization domain
range: 22862455775508270tt399tt539

22862455775508270tt399
type: Position
type: ExactPosition
position: 399
reference: Q9HK17-1

22862455775508270tt539
type: Position
type: ExactPosition
position: 539
reference: Q9HK17-1

SIPB98E766154343C5E
type: Region Annotation
comment: Carbamoyl phosphate synthetic domain
range: 22862455775508270tt540tt916

22862455775508270tt540
type: Position
type: ExactPosition
position: 540
reference: Q9HK17-1

22862455775508270tt916
type: Position
type: ExactPosition
position: 916
reference: Q9HK17-1

SIPE8A9CC9A666140D5
type: Region Annotation
comment: Allosteric domain
range: 22862455775508270tt916tt1047

22862455775508270tt159
type: Position
type: ExactPosition
position: 159
reference: Q9HK17-1

22862455775508270tt216
type: Position
type: ExactPosition
position: 216
reference: Q9HK17-1

22862455775508270tt284
type: Position
type: ExactPosition
position: 284
reference: Q9HK17-1

22862455775508270tt296
type: Position
type: ExactPosition
position: 296
reference: Q9HK17-1

22862455775508270tt298
type: Position
type: ExactPosition
position: 298
reference: Q9HK17-1

22862455775508270tt691
type: Position
type: ExactPosition
position: 691
reference: Q9HK17-1

22862455775508270tt746
type: Position
type: ExactPosition
position: 746
reference: Q9HK17-1

22862455775508270tt813
type: Position
type: ExactPosition
position: 813
reference: Q9HK17-1

22862455775508270tt825
type: Position
type: ExactPosition
position: 825
reference: Q9HK17-1

22862455775508270tt827
type: Position
type: ExactPosition
position: 827
reference: Q9HK17-1

1
subclass of: CHEBI_18420

2
subclass of: CHEBI_18420

3
subclass of: CHEBI_18420

4
subclass of: CHEBI_18420

Q9HK17-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 116852
value: MPRRDDIHRILVIGSGPVVIGQAAEFDYSGSQACLSLREEGYYVVLLNSNPATIQTDHRIADRVYIEPITVEAVERIIEKEKIDAIEPHMGGQTALNLAVKLKNSGILQRYGIKIIGTPVESIELAEDREKFYEFLKAMGEPQPARYRIRRDHIDEDVASIPDIPVIVRTSFSLGGTGGSIVQNRQDLLAMAENLFRASDIDYLEVNESLEGMKEIEYEVIRDSFGNCITVCNMENLDPMGVHTGESIVVTPSQTLSDIEYQMLRDSAIRIISGLGIEGACNIQFALSEGRYYVIEVNPRTSRSSALASKATGYPIARIAAKIAAGYGLHEIKNPITKSTFAAYEPSLDYVTVKIPRWPFDKFSVDRTIGVQMKSIGEVMGIGRTFEEALMKAIASLDNAFSSNIRLHVPDDELWRLIGKPNDRRIFAIFEGLFRNFDVKRMSRLSGYDEYFIEKMRNIVEALRNMDMGRIPENLLRIKRIGIPDEIISAFCGVPADTITKYRIDRNIMPVYKRIDTCSGEFEVAVPYMYSTYEDEDETPDLSGSIMIIGSGPNRIAQGLEFDYGSVKAILALRDMGYRSIMLNSNPETVSTDFDISDALFFEPVTPEYVVNVIRRSGCAGLIVQFSGQTGQNMARRIEEILGKHIVLGTSTESIDRIEDRTVFSRVIEGLGIKQPPFAIAENENDTVRKAMGLGLPIILRSSHVIGGRSMEIIYDVDYLADRAREIFAISKNVLVSKYLENAVEMDVDFVSDGTSYSICGIIVHIEEAGVHSGDATMVYGPGIVPVDIEKKIEGIVGSMVREFRLIGLSNLQIAVRDGDVYVIELNARSSRSVPFISKATGIDWVRLAVECMIGSRIENKRMEAKSYFLKVSVFPFSKFSDMDVVYGPEMKSTGEAMYPGRTLAEALRKSLQRSISSVLITVRDEDKPRIVDIARILLEKGVKLYATAGTSKFLADHGIPTETLYRVRDRREPRILDMISSGSIDMVINTTEMTAGAVRDGFKIRRICIMRGIPLIMNINLARAYAEALGQVEVDYREIGDYLQVS

http://purl.uniprot.org/uniprot/Q9HK17#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q9HK17#attribution-CA6C1FA7B5F62B01D08D95E25A4BBCA0
manual: true
evidence: ECO_0000255
source: MF_01210

http://purl.uniprot.org/uniprot/Q9HK17#attribution-5EAC2F7D271A79B0C924FB087C595440
manual: true
evidence: ECO_0000255
source: PRU01202

Q97AJ3
type: Protein
reviewed: true
created: 2002-08-02
modified: 2023-02-22
version: 135
mnemonic: CARB_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP70BCCA51962F43C3
alternative name: SIP628E9B800447372D
enzyme: http://purl.uniprot.org/enzyme/6.3.5.5
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP68A797395CAE094D
annotation: SIP498D6E4FBC55C7D5
annotation: SIPA863E0C2C5D35F80
annotation: SIP44B1BD8232AA8553
annotation: SIPF2F46140D6391802
annotation: SIP8E80C47A1AE076F6
annotation: PRO_0000145087
annotation: SIPF249E9E197A1B36E
annotation: SIPE693D46E30F8A112
annotation: SIP1A1A4435E22575FB
annotation: SIPCE666C189ACFED34
annotation: SIPF59ABC379650A4DA
annotation: SIP62FF4CEBDD1B61F0
annotation: SIP559B7B934B64FD5F
annotation: SIP82868EB8C70B4BB5
annotation: SIPD7567E4DF1573C2D
annotation: SIP3A075E304206F12D
annotation: SIP7DE40B1B94397DB9
annotation: SIP722FC694AF96F41E
annotation: SIP9275E53AFF83222A
annotation: SIPB768D206333E64F4
annotation: SIP8A592881A4F5D404
annotation: SIP82153C66F564525B
annotation: SIPB48491CD44338777
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/665
classified with: http://purl.uniprot.org/keywords/677
classified with: GO_0005524
classified with: GO_0004088
classified with: GO_0046872
classified with: GO_0044205
classified with: GO_0006526
sequence: Q97AJ3-1
proteome: Chromosome

Q97AJ3-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP70BCCA51962F43C3
type: Structured Name
full name: Carbamoyl-phosphate synthase large chain
ec name: 6.3.5.5

SIP628E9B800447372D
type: Structured Name
full name: Carbamoyl-phosphate synthetase ammonia chain

carB
type: Gene
locus name: TV0817
orf name: TVG0823863

SIP498D6E4FBC55C7D5
type: Cofactor Annotation
comment: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
cofactor: CHEBI_18420
cofactor: CHEBI_29035

SIPF2F46140D6391802
type: Subunit Annotation
comment: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

SIP8E80C47A1AE076F6
type: Similarity Annotation
comment: Belongs to the CarB family.

PRO_0000145087
type: Chain Annotation
comment: Carbamoyl-phosphate synthase large chain
mass: 116771
range: 22862382594929454tt1tt1044

22862382594929454tt1
type: Position
type: ExactPosition
position: 1
reference: Q97AJ3-1

22862382594929454tt1044
type: Position
type: ExactPosition
position: 1044
reference: Q97AJ3-1

SIPF249E9E197A1B36E
type: Domain Extent Annotation
comment: ATP-grasp 1
range: 22862382594929454tt133tt325

22862382594929454tt133
type: Position
type: ExactPosition
position: 133
reference: Q97AJ3-1

22862382594929454tt325
type: Position
type: ExactPosition
position: 325
reference: Q97AJ3-1

SIPE693D46E30F8A112
type: Domain Extent Annotation
comment: ATP-grasp 2
range: 22862382594929454tt665tt854

22862382594929454tt665
type: Position
type: ExactPosition
position: 665
reference: Q97AJ3-1

22862382594929454tt854
type: Position
type: ExactPosition
position: 854
reference: Q97AJ3-1

SIP1A1A4435E22575FB
type: Domain Extent Annotation
comment: MGS-like
range: 22862382594929454tt911tt1044

22862382594929454tt911
type: Position
type: ExactPosition
position: 911
reference: Q97AJ3-1

SIPCE666C189ACFED34
type: Region Annotation
comment: Carboxyphosphate synthetic domain
range: 22862382594929454tt1tt398

22862382594929454tt398
type: Position
type: ExactPosition
position: 398
reference: Q97AJ3-1

SIPF59ABC379650A4DA
type: Region Annotation
comment: Oligomerization domain
range: 22862382594929454tt399tt539

22862382594929454tt399
type: Position
type: ExactPosition
position: 399
reference: Q97AJ3-1

22862382594929454tt539
type: Position
type: ExactPosition
position: 539
reference: Q97AJ3-1

SIP62FF4CEBDD1B61F0
type: Region Annotation
comment: Carbamoyl phosphate synthetic domain
range: 22862382594929454tt540tt916

22862382594929454tt540
type: Position
type: ExactPosition
position: 540
reference: Q97AJ3-1

22862382594929454tt916
type: Position
type: ExactPosition
position: 916
reference: Q97AJ3-1

SIP559B7B934B64FD5F
type: Region Annotation
comment: Allosteric domain
range: 22862382594929454tt916tt1044

22862382594929454tt159
type: Position
type: ExactPosition
position: 159
reference: Q97AJ3-1

22862382594929454tt216
type: Position
type: ExactPosition
position: 216
reference: Q97AJ3-1

22862382594929454tt284
type: Position
type: ExactPosition
position: 284
reference: Q97AJ3-1

22862382594929454tt296
type: Position
type: ExactPosition
position: 296
reference: Q97AJ3-1

22862382594929454tt298
type: Position
type: ExactPosition
position: 298
reference: Q97AJ3-1

22862382594929454tt691
type: Position
type: ExactPosition
position: 691
reference: Q97AJ3-1

22862382594929454tt746
type: Position
type: ExactPosition
position: 746
reference: Q97AJ3-1

22862382594929454tt813
type: Position
type: ExactPosition
position: 813
reference: Q97AJ3-1

22862382594929454tt825
type: Position
type: ExactPosition
position: 825
reference: Q97AJ3-1

22862382594929454tt827
type: Position
type: ExactPosition
position: 827
reference: Q97AJ3-1

1
subclass of: CHEBI_18420

2
subclass of: CHEBI_18420

3
subclass of: CHEBI_18420

4
subclass of: CHEBI_18420

Q97AJ3-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 116771
value: MPKREDISKILVIGSGPVVIGQAAEFDYSASQACRSLREEGYEVVLLNSNPATIQTDHEIADRVYIEPITVEAVETIIRKEEIDAIEPHMGGQTALNLVVSLKKMGIIDKYGIKIIGTPVESIEISEDRQKFHDFLISIGERDPERYRISRSNYKEEIEKIPFMPVIVRTSFSLGGSGGNIVKTKEELKAYAEELFRGIDEDYIEVNRSLAGLKELEYEMIRDSIGNCITVCNMENLDPMGVHTGESIVVTPSQTLSDIQYHMLRDAAIKIVSGLGIVGACNIQFALDGNDYYVVEVNPRTSRSSALASKATGYPIARIAAKIAVGYNLTEIRNPITKNTFAAFEPSLDYVTVKIPRWPFDKFSVDRTIGVQMKSIGEVMGIGRTFEEALMKAIASLDIDLSYRLRLYVSDEEIWNLVRTPNDRRIFAIFEALFRDFPVDRIMEESMYDRYFIEKMQNIVDYLKTLEFGHIPENLISLKKLGISDEIIGRTCGIDPDEITRYRITNRILPVFKEIDTCSGEFEVIAPYLYSTYEDEDELPGISGFVAIIGSGPNRIAQGLEFDYGAVKAITALRKMGVGSVMINSNPETVSTDFDVSDALFFEPITVEHVSNILAKANLRGLIVQFSGQTGQNIARRIENVLGSSVVMGTSSESIDRIEDRSLFSKRLEAMGIDQPKFEVATNAEEAINKSLALGLPVILRASHVIGGRAMDIIYDYDFLVERSREVFENVNSVLVSKYLENAVEIDVDFVSNGEDFQICGILVHIEEAGVHSGDATMIFGPKIVPQAAEEKIKSIVGKLVREFNLIGISNLQAAIKDDEVYVIELNARSSRSIPFISKATGYNWVELAVSAIMTGKLEKVSVSSKGYFVKVSVFPFSKFNDMDVSLGPEMKSTGEAMYPGFTMEEAIRKSILRDIKSVFISVRDDDKPRIIEAASIMKQNGLKIYATMGTSRYLRERGIECETVYRIKDERKPRIYDMILAGYIDLVINTPEMNAGSVRDGFKIRRLCVRKGIPLVTNINLANAYSKCLSYTNIDYREISSYH

http://purl.uniprot.org/uniprot/Q97AJ3#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q97AJ3#attribution-CA6C1FA7B5F62B01D08D95E25A4BBCA0
manual: true
evidence: ECO_0000255
source: MF_01210

http://purl.uniprot.org/uniprot/Q97AJ3#attribution-5EAC2F7D271A79B0C924FB087C595440
manual: true
evidence: ECO_0000255
source: PRU01202

Q6L2V8
type: Protein
reviewed: true
created: 2005-08-30
modified: 2023-02-22
version: 100
mnemonic: CBIA_PICTO
old mnemonic: COBB_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP9443CA79431E1C67
alternative name: SIP0334C7BEA9B7505F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.11
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP387EE28ED837C788
annotation: SIP9BFE9816EABD3CBF
annotation: SIP379C7A4264820419
annotation: SIPE0BA22D73D6442CF
annotation: SIP11E43692A2ABE299
annotation: SIP047D4350293D92CD
annotation: SIP70E832ED7627AEF0
annotation: PRO_0000141278
annotation: SIP87DBB116199EE4D7
annotation: SIP638AB0790391432D
annotation: SIPCC33D3BABEE82FE3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0042242
classified with: GO_0009236
classified with: GO_0006541
sequence: Q6L2V8-1
proteome: Chromosome

Q6L2V8-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG00106
type: Resource
database: eggNOG
comment: Archaea

cd05388
type: Resource
database: CDD
comment: CobB_N
signature sequence match: CDD cd05388 match 1

cd03130
type: Resource
database: CDD
comment: GATase1_CobB
signature sequence match: CDD cd03130 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1
signature sequence match: Gene3D 3.40.50.300 match 2

MF_00027
type: Resource
database: HAMAP
comment: CobB_CbiA
signature sequence match: HAMAP MF 00027 match 1

IPR004484
type: Resource
database: InterPro
comment: CbiA_synth

IPR002586
type: Resource
database: InterPro
comment: CobQ/CobB/MinD/ParA_Nub-bd_dom

IPR011698
type: Resource
database: InterPro
comment: GATase_3

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

PTHR43873
type: Resource
database: PANTHER
comment: COBYRINATE A,C-DIAMIDE SYNTHASE
signature sequence match: PANTHER PTHR43873 match 1

PTHR43873:SF1
type: Resource
database: PANTHER
comment: COBYRINATE A,C-DIAMIDE SYNTHASE
signature sequence match: PANTHER PTHR43873:SF1 match 1

PF01656
type: Resource
database: Pfam
comment: CbiA
signature sequence match: Pfam PF01656 match 1

PF07685
type: Resource
database: Pfam
comment: GATase_3
signature sequence match: Pfam PF07685 match 1

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1
signature sequence match: SUPFAM SSF52540 match 2

TIGR00379
type: Resource
database: TIGRFAMs
comment: cobB
signature sequence match: TIGRFAMs TIGR00379 match 1

PS51274
type: Resource
database: PROSITE
comment: GATASE_COBBQ
signature sequence match: PROSITE PS51274 match 1

SIP9443CA79431E1C67
type: Structured Name
full name: Cobyrinate a,c-diamide synthase
ec name: 6.3.5.11

SIP0334C7BEA9B7505F
type: Structured Name
full name: Cobyrinic acid a,c-diamide synthetase

cbiA
type: Gene
locus name: PTO0108

SIP387EE28ED837C788
type: Function Annotation
comment: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.

SIP11E43692A2ABE299
type: Domain Annotation
comment: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.

SIP047D4350293D92CD
type: Annotation
comment: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

SIP70E832ED7627AEF0
type: Similarity Annotation
comment: Belongs to the CobB/CbiA family.

PRO_0000141278
type: Chain Annotation
comment: Cobyrinate a,c-diamide synthase
mass: 49267
range: 22859174003488814tt1tt440

22859174003488814tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L2V8-1

22859174003488814tt440
type: Position
type: ExactPosition
position: 440
reference: Q6L2V8-1

SIP87DBB116199EE4D7
type: Domain Extent Annotation
comment: GATase cobBQ-type
range: 22859174003488814tt247tt428

22859174003488814tt247
type: Position
type: ExactPosition
position: 247
reference: Q6L2V8-1

22859174003488814tt428
type: Position
type: ExactPosition
position: 428
reference: Q6L2V8-1

SIP638AB0790391432D
type: Active Site Annotation
comment: Nucleophile
range: 22859174003488814tt329tt329

22859174003488814tt329
type: Position
type: ExactPosition
position: 329
reference: Q6L2V8-1

SIPCC33D3BABEE82FE3
type: Site Annotation
comment: Increases nucleophilicity of active site Cys
range: 22859174003488814tt420tt420

22859174003488814tt420
type: Position
type: ExactPosition
position: 420
reference: Q6L2V8-1

Q6L2V8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 49267
value: MKINSIIIGAPSSSSGKTTISIGIMRALSRRLRVQPFKVGPDYIDPGYHNIATGRFSSNLDTWMSSREKMKEIFIKRSTGSDISIIEGVMGLYDGKQPDKDTGSTAEVARTLKSPVIIVIDISAMARTAAAIILGLIKMDKRLRISGVILNNAGSDYHCSIVRTAIEKYTGIPVIGCVKRSDDLKIDDRYLGLKTAMEDDNSGKIDKIADIIERSVDLDLLIKISKESGDISFKSGLFSKKNVNRVRIAIAYDAAFNFYYYDNIEMLKMYGAEIVYFSPLNDYKLPEADGLYIGGGFPELFAERLSDNYSIKKDIMEFFNSGRPVFAECGGYMYLSRGIKINGKYYEMASIINGESYMDSLILGYRNIRAESNNILMMGGWHVKGHEFHYSRLNVNANAYKTERGPDGISTKNLLAGYMHLYFPSNPRIPERFVRSCYNV

http://purl.uniprot.org/uniprot/Q6L2V8#attribution-E55F6965EEA6D0CF2162254ACAEEE969
manual: true
evidence: ECO_0000255
source: MF_00027

Q9HIX6
type: Protein
reviewed: true
created: 2001-04-27
modified: 2023-02-22
version: 108
mnemonic: CBIA_THEAC
old mnemonic: COBB_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP9443CA79431E1C67
alternative name: SIP0334C7BEA9B7505F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.11
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPEEFE35585F0FBBE1
annotation: SIP6BC479A4DDD0F015
annotation: SIPBD06671608BB0D5A
annotation: SIPC8702571F933DA64
annotation: SIP3D5C92A404C1EBF7
annotation: SIP4A1225225F157C32
annotation: SIP33874DE2497A0833
annotation: PRO_0000141282
annotation: SIPBC6488FCFA98B1D4
annotation: SIPD69E3C8085BB9496
annotation: SIP855EFE2253E4471C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0042242
classified with: GO_0009236
classified with: GO_0006541
sequence: Q9HIX6-1
proteome: Chromosome

Q9HIX6-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

SIP9443CA79431E1C67
type: Structured Name
full name: Cobyrinate a,c-diamide synthase
ec name: 6.3.5.11

SIP0334C7BEA9B7505F
type: Structured Name
full name: Cobyrinic acid a,c-diamide synthetase

cbiA
type: Gene
locus name: Ta1200

SIPEEFE35585F0FBBE1
type: Function Annotation
comment: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.

SIP3D5C92A404C1EBF7
type: Domain Annotation
comment: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.

SIP4A1225225F157C32
type: Annotation
comment: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

SIP33874DE2497A0833
type: Similarity Annotation
comment: Belongs to the CobB/CbiA family.

PRO_0000141282
type: Chain Annotation
comment: Cobyrinate a,c-diamide synthase
mass: 48537
range: 22862455744509486tt1tt443

22862455744509486tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HIX6-1

22862455744509486tt443
type: Position
type: ExactPosition
position: 443
reference: Q9HIX6-1

SIPBC6488FCFA98B1D4
type: Domain Extent Annotation
comment: GATase cobBQ-type
range: 22862455744509486tt244tt435

22862455744509486tt244
type: Position
type: ExactPosition
position: 244
reference: Q9HIX6-1

22862455744509486tt435
type: Position
type: ExactPosition
position: 435
reference: Q9HIX6-1

SIPD69E3C8085BB9496
type: Active Site Annotation
comment: Nucleophile
range: 22862455744509486tt327tt327

22862455744509486tt327
type: Position
type: ExactPosition
position: 327
reference: Q9HIX6-1

SIP855EFE2253E4471C
type: Site Annotation
comment: Increases nucleophilicity of active site Cys
range: 22862455744509486tt427tt427

22862455744509486tt427
type: Position
type: ExactPosition
position: 427
reference: Q9HIX6-1

Q9HIX6-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 48537
value: MKVPRLIVAGTESGAGKTTITISIILKLLANQMKVKPYKIGPDYIDPQFHRLASGVPSENLDLWMMNDDQIRYLLIEGSREFDISVIEGVMGLFDGAGSDFTGSTYDLARRTGTPIVLVIDGYGISATAAAIVSGIKAYAGELLRGVIVTRVSGESHYRLIRDAVEEKTGVPVLGYMIRNEKAVLESRHLGLVQAYEIDEIREIFGAIDSSTVIDMHQIIDIARSADKLETLYSPEIERLGTFKVSVAMDSAFDFYYEENLRMLKRMGASIRYFSPMGNEVPDADSDLIYLGGGYPEVFAGKLQSATDTIEAIRHAASIGTGVYAECGGYMFLCRSLESTDGHIYGGVGIIPASVYMDASLVIGYREISAKRDTSILRAGETARGHEFHKSRIRFDGPYDHPFVLKSRSSSFEDGFSSGSVTATYAHIHFLSNPRVAENLLIA

http://purl.uniprot.org/uniprot/Q9HIX6#attribution-E55F6965EEA6D0CF2162254ACAEEE969
manual: true
evidence: ECO_0000255
source: MF_00027

Q97BP4
type: Protein
reviewed: true
created: 2002-05-27
modified: 2023-02-22
version: 109
mnemonic: CBIA_THEVO
old mnemonic: COBB_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP9443CA79431E1C67
alternative name: SIP0334C7BEA9B7505F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.11
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP28AF815F8C8C2A05
annotation: SIP1C10B73557FB83E8
annotation: SIPE7A1AEB35BDFDE54
annotation: SIP848BC5CD37976AA3
annotation: SIP74C3EB567B5893A6
annotation: SIPFDE324F037198496
annotation: SIP2C4C48F8D381DF7D
annotation: PRO_0000141283
annotation: SIPEE12833E8704E5F2
annotation: SIP16A2427C42AF46AC
annotation: SIPD62DBDCC3F6FEEEF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: GO_0005524
classified with: GO_0042242
classified with: GO_0009236
classified with: GO_0006541
sequence: Q97BP4-1
proteome: Chromosome

Q97BP4-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP9443CA79431E1C67
type: Structured Name
full name: Cobyrinate a,c-diamide synthase
ec name: 6.3.5.11

SIP0334C7BEA9B7505F
type: Structured Name
full name: Cobyrinic acid a,c-diamide synthetase

cbiA
type: Gene
locus name: TV0411
orf name: TVG0399197

SIP28AF815F8C8C2A05
type: Function Annotation
comment: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.

SIP74C3EB567B5893A6
type: Domain Annotation
comment: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.

SIPFDE324F037198496
type: Annotation
comment: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

SIP2C4C48F8D381DF7D
type: Similarity Annotation
comment: Belongs to the CobB/CbiA family.

PRO_0000141283
type: Chain Annotation
comment: Cobyrinate a,c-diamide synthase
mass: 50355
range: 22862382612100142tt1tt454

22862382612100142tt1
type: Position
type: ExactPosition
position: 1
reference: Q97BP4-1

22862382612100142tt454
type: Position
type: ExactPosition
position: 454
reference: Q97BP4-1

SIPEE12833E8704E5F2
type: Domain Extent Annotation
comment: GATase cobBQ-type
range: 22862382612100142tt244tt435

22862382612100142tt244
type: Position
type: ExactPosition
position: 244
reference: Q97BP4-1

22862382612100142tt435
type: Position
type: ExactPosition
position: 435
reference: Q97BP4-1

SIP16A2427C42AF46AC
type: Active Site Annotation
comment: Nucleophile
range: 22862382612100142tt327tt327

22862382612100142tt327
type: Position
type: ExactPosition
position: 327
reference: Q97BP4-1

SIPD62DBDCC3F6FEEEF
type: Site Annotation
comment: Increases nucleophilicity of active site Cys
range: 22862382612100142tt427tt427

22862382612100142tt427
type: Position
type: ExactPosition
position: 427
reference: Q97BP4-1

Q97BP4-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 50355
value: MKVPRVIIAGTNSGVGKTTTTLAVISALKNKGLKVKPYKVGPDYIDPQFHSLLAGATSDNLDLWMIPRERIFQLLADASTSFNISVIEGVMGLLDGFGSTDEGSTLDLARITGTPIILVIDGYGLSGSAAAIVKGFKDFSGDLLAGVIVTRVSGERHYDLIKKAIEDNTNVRVLGYIEKNDEVRLESRHLGLVQASELNSFSDYIERLSKVTHINVDGIIEIARASRDLDPKFSPLLSRVGYAKIAVAYDSAFDFYYEENFRVLRNLGAELVFFSPLNNEIPPEDTDGLYIGGGYPEVFAKKLAYAVDARENIAKLIKKGVPTLAECGGYMYLTRTIVGQDGIEYPGVGIVPAKTFLTDKLILGYREIVSKTSNMLLRHGETARGHEFHRSTIQFQDKVDHPFVLKYKDRFEEDGYYSNNVVASYVHIHFLSNIAIPKRFVEECIRYSKKREIS

http://purl.uniprot.org/uniprot/Q97BP4#attribution-E55F6965EEA6D0CF2162254ACAEEE969
manual: true
evidence: ECO_0000255
source: MF_00027

Q3V8B2
type: Protein
reviewed: true
created: 2006-10-31
modified: 2023-02-22
version: 86
mnemonic: CBID_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP67687FEB328560B8
alternative name: SIPF74281DAD219A3C5
enzyme: http://purl.uniprot.org/enzyme/2.1.1.195
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP243C84E791136A3F
annotation: SIP208462438DC75009
annotation: SIPCCD0891B77E73CD7
annotation: SIP43B5C0052C9280C0
annotation: PRO_0000257788
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/489
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/949
classified with: GO_0043780
classified with: GO_0009236
classified with: GO_0046140
classified with: GO_0032259
sequence: Q3V8B2-1
proteome: Chromosome

Q3V8B2-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG04383
type: Resource
database: eggNOG
comment: Archaea

http://purl.uniprot.org/gene3d/3.30.2110.10
type: Resource
database: Gene3D
comment: CbiD-like
signature sequence match: Gene3D 3.30.2110.10 match 1

http://purl.uniprot.org/gene3d/3.40.50.10720
type: Resource
database: Gene3D
comment: CbiD-like domains
signature sequence match: Gene3D 3.40.50.10720 match 1

MF_00787
type: Resource
database: HAMAP
comment: CbiD
signature sequence match: HAMAP MF 00787 match 1

IPR002748
type: Resource
database: InterPro
comment: CbiD

IPR036074
type: Resource
database: InterPro
comment: CbiD_sf

PTHR35863
type: Resource
database: PANTHER
comment: COBALT-PRECORRIN-5B C(1)-METHYLTRANSFERASE
signature sequence match: PANTHER PTHR35863 match 1

PTHR35863:SF1
type: Resource
database: PANTHER
comment: COBALT-PRECORRIN-5B C(1)-METHYLTRANSFERASE
signature sequence match: PANTHER PTHR35863:SF1 match 1

PF01888
type: Resource
database: Pfam
comment: CbiD
signature sequence match: Pfam PF01888 match 1

PIRSF026782
type: Resource
database: PIRSF
comment: CbiD
signature sequence match: PIRSF PIRSF026782 match 1

SSF111342
type: Resource
database: SUPFAM
comment: CbiD-like
signature sequence match: SUPFAM SSF111342 match 1

TIGR00312
type: Resource
database: TIGRFAMs
comment: cbiD
signature sequence match: TIGRFAMs TIGR00312 match 1

SIP67687FEB328560B8
type: Structured Name
full name: Cobalt-precorrin-5B C(1)-methyltransferase
ec name: 2.1.1.195

SIPF74281DAD219A3C5
type: Structured Name
full name: Cobalt-precorrin-6A synthase

cbiD
type: Gene
locus name: PTO0110

SIP243C84E791136A3F
type: Function Annotation
comment: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

SIP43B5C0052C9280C0
type: Similarity Annotation
comment: Belongs to the CbiD family.

PRO_0000257788
type: Chain Annotation
comment: Cobalt-precorrin-5B C(1)-methyltransferase
mass: 36506
range: 22855918517629486tt1tt341

22855918517629486tt1
type: Position
type: ExactPosition
position: 1
reference: Q3V8B2-1

22855918517629486tt341
type: Position
type: ExactPosition
position: 341
reference: Q3V8B2-1

Q3V8B2-1
type: Simple Sequence
modified: 2005-10-11
version: 1
mass: 36506
value: MPRYGYTTGTCATAATRAAIIALATGRKLKSVEVKLPSKKNAIININDVEIKEDYAMASVVKDGGDDPDVTTGLVIYSKVSFTDSGIYVDGGEGIGRVTKEGLPVKPGNAAINPVPMRMIKNTAMETLSELNISSGLKIIISAPGGDKVALKTCNPKLGIIGGISILGTTGIVVPYSAASWRASIVLAMRVAIKSNYDTVILTTGSRTEEYARKLFNDRYPCIDVGDFIGFSIRRAAENGIKNIIIACMPGKASKLAMGMEDTSSRNSGVDFDFIYKMALSINIKNAEIIKNSNTVNALVDEFTDDGLFKLMAELAKINLRRISNINIDVIIFDMSGNVIS

http://purl.uniprot.org/uniprot/Q3V8B2#attribution-1A412304ECD521A3E6CA697EFAD2EDB0
manual: true
evidence: ECO_0000255
source: MF_00787

Q9HKE5
type: Protein
reviewed: true
created: 2004-06-07
modified: 2023-02-22
version: 96
mnemonic: CBID_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP67687FEB328560B8
alternative name: SIPF74281DAD219A3C5
enzyme: http://purl.uniprot.org/enzyme/2.1.1.195
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP7AB04145CE021762
annotation: SIPC1C7A657E3553858
annotation: SIP3FA848A8B98D3A32
annotation: SIP8B448BFCBC3F84AE
annotation: PRO_0000141701
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/489
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/949
classified with: GO_0043780
classified with: GO_0009236
classified with: GO_0046140
classified with: GO_0032259
sequence: Q9HKE5-1
proteome: Chromosome

Q9HKE5-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

SIP67687FEB328560B8
type: Structured Name
full name: Cobalt-precorrin-5B C(1)-methyltransferase
ec name: 2.1.1.195

SIPF74281DAD219A3C5
type: Structured Name
full name: Cobalt-precorrin-6A synthase

cbiD
type: Gene
locus name: Ta0656

SIP7AB04145CE021762
type: Function Annotation
comment: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

SIP8B448BFCBC3F84AE
type: Similarity Annotation
comment: Belongs to the CbiD family.

PRO_0000141701
type: Chain Annotation
comment: Cobalt-precorrin-5B C(1)-methyltransferase
mass: 38697
range: 22862455776818478tt1tt364

22862455776818478tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKE5-1

22862455776818478tt364
type: Position
type: ExactPosition
position: 364
reference: Q9HKE5-1

Q9HKE5-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 38697
value: MTQSNPFQQYGITSGLAAAAAAKASVLAAMGTISDYVGVPTPIGLRIEVKVEMMKQIDARSGIAAVRKFSGDNPDTLNGALFESRAVIRDDGLINIFAGEGIGVAVSDGLPVRRGDPAINPVARMMIENAVREVSGSAGFDVYISVPGGEDLARDTMNPRVGISGGISILGTTGIEEPVSGPDYEAHIEYLLQTGRCVSTVAVMCPGNTAMRFAESYLRLHPASFILTGDRIGSAIEMAIEKGYREIVVFGLPGKLVKMAAGVMNTHSRIADARFETIAAYAALNGADRDTISKILSSNTVESAFAVLRSIGLLDSVAGAIASRIVERLRSPVWQIRRILLRHDRFRRQAIRVSPVAGHIETGE

http://purl.uniprot.org/uniprot/Q9HKE5#attribution-1A412304ECD521A3E6CA697EFAD2EDB0
manual: true
evidence: ECO_0000255
source: MF_00787

Q97A63
type: Protein
reviewed: true
created: 2004-06-07
modified: 2023-02-22
version: 98
mnemonic: CBID_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP67687FEB328560B8
alternative name: SIPF74281DAD219A3C5
enzyme: http://purl.uniprot.org/enzyme/2.1.1.195
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP66496E6532A5BE04
annotation: SIP88BB58BEC5CA6299
annotation: SIP5D632FD820CBFB80
annotation: SIPE2EDEE35D9480DC1
annotation: PRO_0000141702
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/489
classified with: http://purl.uniprot.org/keywords/949
classified with: GO_0043780
classified with: GO_0009236
classified with: GO_0046140
classified with: GO_0032259
sequence: Q97A63-1
proteome: Chromosome

Q97A63-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP67687FEB328560B8
type: Structured Name
full name: Cobalt-precorrin-5B C(1)-methyltransferase
ec name: 2.1.1.195

SIPF74281DAD219A3C5
type: Structured Name
full name: Cobalt-precorrin-6A synthase

cbiD
type: Gene
locus name: TV0947
orf name: TVG0972668

SIP66496E6532A5BE04
type: Function Annotation
comment: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

SIPE2EDEE35D9480DC1
type: Similarity Annotation
comment: Belongs to the CbiD family.

PRO_0000141702
type: Chain Annotation
comment: Cobalt-precorrin-5B C(1)-methyltransferase
mass: 39916
range: 22862382593618734tt1tt378

22862382593618734tt1
type: Position
type: ExactPosition
position: 1
reference: Q97A63-1

22862382593618734tt378
type: Position
type: ExactPosition
position: 378
reference: Q97A63-1

Q97A63-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 39916
value: MMYASDGSGVNPFQQYGITTGLTAAAAAKACTLTVLKGVQNRVVVPTPIGIRIEVKVVESVRIDESSGYASAEKFSGDNPDQLNGITIRCHCKVVKKQENGRSKITISGNAGIGVVEKDGLGIRPGEKAISQGARKMIEDAVREAAGGYDVELSISVPNGEEFAKLTMNEKVGVFGGISVLGTTGIEEPVSTEEYELHLKYIVAAGRCVSKIIVLCPGNTALKFAKKYFALPDKAFVLIGDKVGAAVSASIESAYDHVVIFGLPGKLVKIAAGIYNTHSKVADGRMETLAAVAAMYGISKGAVKRIMESSNTGEAISIIEQEGIVAEVLNTIASRISNRLKADFSRSVGFSVVIIDHDGKIIGSHLDGHIKEVLKYGK

http://purl.uniprot.org/uniprot/Q97A63#attribution-1A412304ECD521A3E6CA697EFAD2EDB0
manual: true
evidence: ECO_0000255
source: MF_00787

Q9HKE4
type: Protein
reviewed: true
created: 2004-06-07
modified: 2023-05-03
version: 107
mnemonic: CBIT_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIPEA40A8180F39DA5B
enzyme: http://purl.uniprot.org/enzyme/2.1.1.196
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP845C4536BC632D5C
annotation: SIP38EC2F58287C7BF9
annotation: SIPE3A25D17629C1BA8
annotation: SIP9CBBA2D010BA9ACF
annotation: PRO_0000134946
annotation: SIP350A85201F6AEB7C
annotation: SIPD3BB58293709450C
annotation: SIPC2F2B189ACEADE4C
annotation: SIPE543A9AA9E5755B9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/489
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/949
classified with: GO_0043776
classified with: GO_0008276
classified with: GO_0009236
classified with: GO_0046140
classified with: GO_0032259
sequence: Q9HKE4-1
proteome: Chromosome

Q9HKE4-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

arCOG00977
type: Resource
database: eggNOG
comment: Archaea

cd02440
type: Resource
database: CDD
comment: AdoMet_MTases
signature sequence match: CDD cd02440 match 1

http://purl.uniprot.org/gene3d/3.40.50.150
type: Resource
database: Gene3D
comment: Vaccinia Virus protein VP39
signature sequence match: Gene3D 3.40.50.150 match 1

MF_00786
type: Resource
database: HAMAP
comment: CbiT
signature sequence match: HAMAP MF 00786 match 1

IPR023475
type: Resource
database: InterPro
comment: CbiT

IPR014008
type: Resource
database: InterPro
comment: Cbl_synth_MTase_CbiT

IPR041698
type: Resource
database: InterPro
comment: Methyltransf_25

IPR029063
type: Resource
database: InterPro
comment: SAM-dependent_MTases_sf

PTHR43182
type: Resource
database: PANTHER
comment: COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING)
signature sequence match: PANTHER PTHR43182 match 1

PTHR43182:SF1
type: Resource
database: PANTHER
comment: COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE
signature sequence match: PANTHER PTHR43182:SF1 match 1

PF13649
type: Resource
database: Pfam
comment: Methyltransf_25
signature sequence match: Pfam PF13649 match 1

SSF53335
type: Resource
database: SUPFAM
comment: S-adenosyl-L-methionine-dependent methyltransferases
signature sequence match: SUPFAM SSF53335 match 1

TIGR02469
type: Resource
database: TIGRFAMs
comment: CbiT
signature sequence match: TIGRFAMs TIGR02469 match 1

SIPEA40A8180F39DA5B
type: Structured Name
full name: Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)
ec name: 2.1.1.196

cbiT
type: Gene
locus name: Ta0657

SIP845C4536BC632D5C
type: Function Annotation
comment: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

SIP9CBBA2D010BA9ACF
type: Similarity Annotation
comment: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.

PRO_0000134946
type: Chain Annotation
comment: Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)
mass: 22628
range: 22862455776818222tt1tt202

22862455776818222tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKE4-1

22862455776818222tt202
type: Position
type: ExactPosition
position: 202
reference: Q9HKE4-1

22862455776818222tt29
type: Position
type: ExactPosition
position: 29
reference: Q9HKE4-1

22862455776818222tt53
type: Position
type: ExactPosition
position: 53
reference: Q9HKE4-1

22862455776818222tt57
type: Position
type: ExactPosition
position: 57
reference: Q9HKE4-1

22862455776818222tt77
type: Position
type: ExactPosition
position: 77
reference: Q9HKE4-1

22862455776818222tt106
type: Position
type: ExactPosition
position: 106
reference: Q9HKE4-1

Q9HKE4-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 22628
value: MRMEGENWVYEVRGIPDEFFQRSEGIPMTKREIRIISLSDLRIRPGMRVMDIGCGSGSMTVEISNIIGENGSVTGLDVSGEAADLTMRNCRNLCRFSNYRIVISDVYKYDSDEEFDAVFVGGGTARIHDLFERIERMVHHASRVVVNAIQIHTAYLSLEEMNTRGYSGVNITQVMVSNGMRTSEGYAMIARNPVFIISGDAP

http://purl.uniprot.org/uniprot/Q9HKE4#attribution-15CD926CB94157EF89F9A7B2E1CCA386
manual: true
evidence: ECO_0000255
source: MF_00786

Q97A64
type: Protein
reviewed: true
created: 2004-06-07
modified: 2023-05-03
version: 113
mnemonic: CBIT_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIPEA40A8180F39DA5B
enzyme: http://purl.uniprot.org/enzyme/2.1.1.196
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP5176AF1FA811EEA4
annotation: SIP2D331BAB80B90126
annotation: SIP13E2ECAC4DBBC3BD
annotation: SIP98867C105CF69B02
annotation: PRO_0000134947
annotation: SIP13393A2DF4D38FBE
annotation: SIPDC683BA48B46E231
annotation: SIPCE8E2216BFF3FCD5
annotation: SIP9AC4F070CE0508E2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/489
classified with: http://purl.uniprot.org/keywords/949
classified with: GO_0043776
classified with: GO_0008276
classified with: GO_0009236
classified with: GO_0046140
classified with: GO_0032259
sequence: Q97A64-1
proteome: Chromosome

Q97A64-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

PF01135
type: Resource
database: Pfam
comment: PCMT
signature sequence match: Pfam PF01135 match 1

SIPEA40A8180F39DA5B
type: Structured Name
full name: Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)
ec name: 2.1.1.196

cbiT
type: Gene
locus name: TV0946
orf name: TVG0972073

SIP5176AF1FA811EEA4
type: Function Annotation
comment: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

SIP98867C105CF69B02
type: Similarity Annotation
comment: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.

PRO_0000134947
type: Chain Annotation
comment: Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)
mass: 21884
range: 22862382593618990tt1tt201

22862382593618990tt1
type: Position
type: ExactPosition
position: 1
reference: Q97A64-1

22862382593618990tt201
type: Position
type: ExactPosition
position: 201
reference: Q97A64-1

22862382593618990tt28
type: Position
type: ExactPosition
position: 28
reference: Q97A64-1

22862382593618990tt52
type: Position
type: ExactPosition
position: 52
reference: Q97A64-1

22862382593618990tt56
type: Position
type: ExactPosition
position: 56
reference: Q97A64-1

22862382593618990tt76
type: Position
type: ExactPosition
position: 76
reference: Q97A64-1

22862382593618990tt105
type: Position
type: ExactPosition
position: 105
reference: Q97A64-1

Q97A64-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 21884
value: MESEKSKFDYYIVTPDSLFERVDGIPMTKEEIRLISLNRLGVRNGGHFLDIGTGTGSVAVDMSRLAGPNGKIIALDRDEKAIKLARINLDRLSPYKNIQLVLADAYAYSPADSFDAIFIGGGTGDLPNLVSKYVPFLKSGARVVINAIQVKTLNDAVESLELNNFRNVSVIEVQISVGMKTGSSYAMIARNPIFVVSGEQP

http://purl.uniprot.org/uniprot/Q97A64#attribution-15CD926CB94157EF89F9A7B2E1CCA386
manual: true
evidence: ECO_0000255
source: MF_00786

Q6L1N2
type: Protein
reviewed: true
created: 2005-08-16
modified: 2023-05-03
version: 100
mnemonic: CCA_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP28A10AA6E75F6643
alternative name: SIPFD662999492C3B2C
alternative name: SIP6045763066331F64
alternative name: SIP8E12E33E3E46AA42
alternative name: SIP94C33CD9C198DAE5
alternative name: SIP54E14E5A68BDE348
enzyme: http://purl.uniprot.org/enzyme/2.7.7.72
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIPA9B7A93F706A8D78
annotation: SIPC789F81DBBBB510C
annotation: SIPDD3ADE37978B3120
annotation: SIP84464EF9BC2737B9
annotation: SIPC96258229E15D5C3
annotation: SIPE110DACF1485622A
annotation: PRO_0000139075
annotation: SIP11392AB1617CCBE8
annotation: SIPE423051508088BAD
annotation: SIPBFA953B3AC895849
annotation: SIP389642F3F74EC321
annotation: SIP761310C9B21EC471
annotation: SIP3778BE6F742AEF04
annotation: SIP8E63AAB7DCE18073
annotation: SIP8E4A264E6AE48213
annotation: SIP562CFD3C5C70900D
annotation: SIP731F5EE0B6EA3BB3
annotation: SIP4022AD93D2CC910C
annotation: SIP65B7419A4112608E
annotation: SIPF64CE9E4FCAAC73D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/692
classified with: http://purl.uniprot.org/keywords/694
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005524
classified with: GO_0004810
classified with: GO_0000287
classified with: GO_0000049
classified with: GO_0042245
classified with: GO_0001680
sequence: Q6L1N2-1
proteome: Chromosome

Q6L1N2-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG04249
type: Resource
database: eggNOG
comment: Archaea

cd05400
type: Resource
database: CDD
comment: NT_2-5OAS_ClassI-CCAase
signature sequence match: CDD cd05400 match 1

http://purl.uniprot.org/gene3d/3.30.70.1550
type: Resource
database: Gene3D
comment: Archaeal tRNA CCA-adding enzyme catalytic domain
signature sequence match: Gene3D 3.30.70.1550 match 1

http://purl.uniprot.org/gene3d/3.30.460.10
type: Resource
database: Gene3D
comment: Beta Polymerase, domain 2
signature sequence match: Gene3D 3.30.460.10 match 1

http://purl.uniprot.org/gene3d/1.10.1410.30
type: Resource
database: Gene3D
comment: CCA tRNA nucleotidyltransferase, domain 2
signature sequence match: Gene3D 1.10.1410.30 match 1

http://purl.uniprot.org/gene3d/3.30.70.590
type: Resource
database: Gene3D
comment: Poly(A) polymerase predicted RNA binding domain
signature sequence match: Gene3D 3.30.70.590 match 1

MF_01264
type: Resource
database: HAMAP
comment: CCA_arch
signature sequence match: HAMAP MF 01264 match 1

IPR008229
type: Resource
database: InterPro
comment: CCA-adding_arc

IPR042090
type: Resource
database: InterPro
comment: CCA_tRNA_nucleotrans_2

IPR006116
type: Resource
database: InterPro
comment: NT_2-5OAS_ClassI-CCAase

IPR043519
type: Resource
database: InterPro
comment: NT_sf

IPR011068
type: Resource
database: InterPro
comment: NuclTrfase_I-like_C

IPR002934
type: Resource
database: InterPro
comment: Polymerase_NTP_transf_dom

IPR015329
type: Resource
database: InterPro
comment: tRNA_NucTransf2

PTHR39643
type: Resource
database: PANTHER
comment: CCA-ADDING ENZYME
signature sequence match: PANTHER PTHR39643 match 1

PTHR39643:SF1
type: Resource
database: PANTHER
comment: CCA-ADDING ENZYME
signature sequence match: PANTHER PTHR39643:SF1 match 1

PF01909
type: Resource
database: Pfam
comment: NTP_transf_2
signature sequence match: Pfam PF01909 match 1

PF09249
type: Resource
database: Pfam
comment: tRNA_NucTransf2
signature sequence match: Pfam PF09249 match 1

PIRSF005335
type: Resource
database: PIRSF
comment: CCA_arch
signature sequence match: PIRSF PIRSF005335 match 1

SSF81301
type: Resource
database: SUPFAM
comment: Nucleotidyltransferase
signature sequence match: SUPFAM SSF81301 match 1

SSF55003
type: Resource
database: SUPFAM
comment: PAP/Archaeal CCA-adding enzyme, C-terminal domain
signature sequence match: SUPFAM SSF55003 match 1

SSF81631
type: Resource
database: SUPFAM
comment: PAP/OAS1 substrate-binding domain
signature sequence match: SUPFAM SSF81631 match 1

TIGR03671
type: Resource
database: TIGRFAMs
comment: cca_archaeal
signature sequence match: TIGRFAMs TIGR03671 match 1

SIP28A10AA6E75F6643
type: Structured Name
full name: CCA-adding enzyme
ec name: 2.7.7.72

SIPFD662999492C3B2C
type: Structured Name
full name: CCA tRNA nucleotidyltransferase

SIP6045763066331F64
type: Structured Name
full name: tRNA CCA-pyrophosphorylase

SIP8E12E33E3E46AA42
type: Structured Name
full name: tRNA adenylyl-/cytidylyl- transferase

SIP94C33CD9C198DAE5
type: Structured Name
full name: tRNA nucleotidyltransferase

SIP54E14E5A68BDE348
type: Structured Name
full name: tRNA-NT

cca
type: Gene
locus name: PTO0535

SIPA9B7A93F706A8D78
type: Function Annotation
comment: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.

SIP84464EF9BC2737B9
type: Subunit Annotation
comment: Homodimer.

SIPC96258229E15D5C3
type: Annotation
comment: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.

SIPE110DACF1485622A
type: Similarity Annotation
comment: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.

PRO_0000139075
type: Chain Annotation
comment: CCA-adding enzyme
mass: 49220
range: 22859173986185774tt1tt427

22859173986185774tt1
type: Position
type: ExactPosition
position: 1
reference: Q6L1N2-1

22859173986185774tt427
type: Position
type: ExactPosition
position: 427
reference: Q6L1N2-1

22859173986185774tt50
type: Position
type: ExactPosition
position: 50
reference: Q6L1N2-1

22859173986185774tt53
type: Position
type: ExactPosition
position: 53
reference: Q6L1N2-1

22859173986185774tt61
type: Position
type: ExactPosition
position: 61
reference: Q6L1N2-1

22859173986185774tt63
type: Position
type: ExactPosition
position: 63
reference: Q6L1N2-1

22859173986185774tt112
type: Position
type: ExactPosition
position: 112
reference: Q6L1N2-1

22859173986185774tt135
type: Position
type: ExactPosition
position: 135
reference: Q6L1N2-1

22859173986185774tt155
type: Position
type: ExactPosition
position: 155
reference: Q6L1N2-1

22859173986185774tt164
type: Position
type: ExactPosition
position: 164
reference: Q6L1N2-1

Q6L1N2-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 49220
value: MIDYKKILGDYTPDYEESLRLKCIENGIIKKLNDIISSRNIDAEPVSVGSYSKGTNLKNSDLDIFIVFSKKYPKNEMESIGLSLGHYILENGVEKYAEHPYVSGYIENVKIDIVPAYKIEPGQRIVSTVDRTPLHTKYVIENTDENLRNDIRLLKIFMKANNVYGSEVSKAGFSGYLCEILVINFKSFDAVIKYFSKLKGRLIIPENSGKKFQEPVVIVDPVDPTRNAGAAVSLENLSRMKIASKLFLLNKNESFFYPREISPRYHKRGTCIYIITLKRPDIIDDIIYPQVFRFERQIFNIADRYGFMPVSSEINVDNNIEILIELQRDVLPDVSKHAGPPVDSDESINFINVWKDRALRGPYIERDRLYVDSETRIKSFYDALNLELKKMDIGKNLNKLKDGIKIIKYNNSDFNVVKKFFSKDIFH

http://purl.uniprot.org/uniprot/Q6L1N2#attribution-D688308B634744D14F138DDA04EF1955
manual: true
evidence: ECO_0000255
source: MF_01264

Q9HI95
type: Protein
reviewed: true
created: 2005-08-16
modified: 2023-05-03
version: 100
mnemonic: CCA_THEAC
old mnemonic: CCA1_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP28A10AA6E75F6643
alternative name: SIPFD662999492C3B2C
alternative name: SIP6045763066331F64
alternative name: SIP8E12E33E3E46AA42
alternative name: SIP94C33CD9C198DAE5
alternative name: SIP54E14E5A68BDE348
enzyme: http://purl.uniprot.org/enzyme/2.7.7.72
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP71EDEB915A965090
annotation: SIP103950C5A77F052B
annotation: SIPA6128F001A5019B5
annotation: SIPB4BC64638EABC81B
annotation: SIPD33B8A0B1FF13183
annotation: SIP7D55CE86164BF880
annotation: PRO_0000139085
annotation: SIPEC07C070084C0690
annotation: SIPF39386A4A8503FBB
annotation: SIP0DCA85D20BB58EEF
annotation: SIPE6933AF6A7B9EA21
annotation: SIPA2298C48EB4B7246
annotation: SIP43665F005140D25D
annotation: SIP668CAD1B5EA55EFC
annotation: SIP785305BB9C2E876D
annotation: SIPE0A5C302024FD766
annotation: SIP0A7C660877A2EC33
annotation: SIP86B2ECACD96F4619
annotation: SIP46EFFD60DC692AA9
annotation: SIPA56422AD93CC1FF7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/692
classified with: http://purl.uniprot.org/keywords/694
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005524
classified with: GO_0004810
classified with: GO_0000287
classified with: GO_0000049
classified with: GO_0042245
classified with: GO_0001680
sequence: Q9HI95-1
proteome: Chromosome

Q9HI95-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

SIP28A10AA6E75F6643
type: Structured Name
full name: CCA-adding enzyme
ec name: 2.7.7.72

SIPFD662999492C3B2C
type: Structured Name
full name: CCA tRNA nucleotidyltransferase

SIP6045763066331F64
type: Structured Name
full name: tRNA CCA-pyrophosphorylase

SIP8E12E33E3E46AA42
type: Structured Name
full name: tRNA adenylyl-/cytidylyl- transferase

SIP94C33CD9C198DAE5
type: Structured Name
full name: tRNA nucleotidyltransferase

SIP54E14E5A68BDE348
type: Structured Name
full name: tRNA-NT

cca
type: Gene
locus name: Ta1446

SIP71EDEB915A965090
type: Function Annotation
comment: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.

SIPB4BC64638EABC81B
type: Subunit Annotation
comment: Homodimer.

SIPD33B8A0B1FF13183
type: Annotation
comment: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.

SIP7D55CE86164BF880
type: Similarity Annotation
comment: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.

PRO_0000139085
type: Chain Annotation
comment: CCA-adding enzyme
mass: 49400
range: 22862455742477614tt1tt431

22862455742477614tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HI95-1

22862455742477614tt431
type: Position
type: ExactPosition
position: 431
reference: Q9HI95-1

22862455742477614tt50
type: Position
type: ExactPosition
position: 50
reference: Q9HI95-1

22862455742477614tt53
type: Position
type: ExactPosition
position: 53
reference: Q9HI95-1

22862455742477614tt61
type: Position
type: ExactPosition
position: 61
reference: Q9HI95-1

22862455742477614tt63
type: Position
type: ExactPosition
position: 63
reference: Q9HI95-1

22862455742477614tt112
type: Position
type: ExactPosition
position: 112
reference: Q9HI95-1

22862455742477614tt135
type: Position
type: ExactPosition
position: 135
reference: Q9HI95-1

22862455742477614tt155
type: Position
type: ExactPosition
position: 155
reference: Q9HI95-1

22862455742477614tt164
type: Position
type: ExactPosition
position: 164
reference: Q9HI95-1

Q9HI95-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 49400
value: MIDYQEVLSRYRPTQEEENKLKIISDDIIRKINSICRSRGLRAEAVIVGSYAKGTNLRDGDLDIFIAFDRDYPEEIINTEGLHIGHAVIPNGREKYAEHPYVSGEIGGVKIDVVPCYKMSFGDKKISAVDRTLLHTEYVNGHLDEKGRDEVRLLKIFTKSIGVYGAEARTFGFSGYLCELLVIRFGSFENVIRYFSKAKGRVLIDLDERFRDPMVLIDPVDPDRNVASPVSLESLSRMKIASKMFLSSPDEGFFQIEHNGKNVQYHDRGTCIMIYSLPKPDLTDDVIYPQVYRFRSVLQKIMESHEIRVISSEIDVSDRIYVLIETPACAEERIRVHTGPPVDTDNAVDFVNSWKARDRSRGPYIVADRLYVDVFTGQRSIEDIVRQEIFNYSIGKNLDRFKKSMEIMKFNVGMKSLPVLDKFFGADVFRK

http://purl.uniprot.org/uniprot/Q9HI95#attribution-D688308B634744D14F138DDA04EF1955
manual: true
evidence: ECO_0000255
source: MF_01264

Q9V302
type: Protein
reviewed: true
created: 2005-08-16
modified: 2023-02-22
version: 72
mnemonic: CCA_THEAI
old mnemonic: CCA2_THEAC
citation: http://purl.uniprot.org/citations/10438486
recommended name: SIP28A10AA6E75F6643
alternative name: SIPFD662999492C3B2C
alternative name: SIP6045763066331F64
alternative name: SIP8E12E33E3E46AA42
alternative name: SIP94C33CD9C198DAE5
alternative name: SIP54E14E5A68BDE348
enzyme: http://purl.uniprot.org/enzyme/2.7.7.72
organism: http://purl.uniprot.org/taxonomy/2303
annotation: SIPE7001C65080A356E
annotation: SIP499F8BE38660C49E
annotation: SIPD71D1D1A195225E6
annotation: SIP12A6EACD5F3D970F
annotation: SIPA437E0F2E58C4CAD
annotation: SIP5954F5EF3C958F09
annotation: PRO_0000139086
annotation: SIPEFBE704D7ED35EAB
annotation: SIP4E9AFD2F2C3F999B
annotation: SIPE3DB873AC975A2C8
annotation: SIP434BFA516F8D80BB
annotation: SIPBD2250EA2ED28152
annotation: SIP82250F24BFB32B57
annotation: SIP554FBF68B6DBF341
annotation: SIPB688792F7F189DA8
annotation: SIPB8EA5D2372C09FC6
annotation: SIPDABE67D4DCD359F4
annotation: SIPEA27B1740C5BEC9C
annotation: SIP2D50B62A64CF3C8F
annotation: SIPBA8FDCE9062FCB9F
annotation: SIP4A9000086CF4B284
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/692
classified with: http://purl.uniprot.org/keywords/694
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005524
classified with: GO_0004810
classified with: GO_0046872
classified with: GO_0003723
classified with: GO_0042245
classified with: GO_0001680
sequence: Q9V302-1

Q9V302-citation-10438486
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

HO-62
type: Strain

SIP28A10AA6E75F6643
type: Structured Name
full name: CCA-adding enzyme
ec name: 2.7.7.72

SIPFD662999492C3B2C
type: Structured Name
full name: CCA tRNA nucleotidyltransferase

SIP6045763066331F64
type: Structured Name
full name: tRNA CCA-pyrophosphorylase

SIP8E12E33E3E46AA42
type: Structured Name
full name: tRNA adenylyl-/cytidylyl- transferase

SIP94C33CD9C198DAE5
type: Structured Name
full name: tRNA nucleotidyltransferase

SIP54E14E5A68BDE348
type: Structured Name
full name: tRNA-NT

cca
type: Gene

SIPE7001C65080A356E
type: Function Annotation
comment: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.

SIP12A6EACD5F3D970F
type: Subunit Annotation
comment: Homodimer.

SIPA437E0F2E58C4CAD
type: Annotation
comment: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.

SIP5954F5EF3C958F09
type: Similarity Annotation
comment: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.

PRO_0000139086
type: Chain Annotation
comment: CCA-adding enzyme
mass: 25546
range: 22862515502330414tt1tf222

22862515502330414tt1
type: Position
type: ExactPosition
position: 1
reference: Q9V302-1

22862515502330414tt222
type: Position
type: ExactPosition
position: 222
reference: Q9V302-1

22862515502330414tt50
type: Position
type: ExactPosition
position: 50
reference: Q9V302-1

22862515502330414tt53
type: Position
type: ExactPosition
position: 53
reference: Q9V302-1

22862515502330414tt61
type: Position
type: ExactPosition
position: 61
reference: Q9V302-1

22862515502330414tt63
type: Position
type: ExactPosition
position: 63
reference: Q9V302-1

22862515502330414tt112
type: Position
type: ExactPosition
position: 112
reference: Q9V302-1

22862515502330414tt135
type: Position
type: ExactPosition
position: 135
reference: Q9V302-1

22862515502330414tt155
type: Position
type: ExactPosition
position: 155
reference: Q9V302-1

22862515502330414tt164
type: Position
type: ExactPosition
position: 164
reference: Q9V302-1

Q9V302-1
type: Simple Sequence
modified: 2000-05-01
version: 1
fragment: single
mass: 25546
value: MIDYQEVLSRYRPTQEEENRLRIISDDIIRKINSICRSRRLRAEAVIVGSYAKGTNLRDGDLDIFIAFDRDYPEEIINTEGLHIGHAVIPNGREKYAEHPYVSGEIGGVKIDVVPCYKMSFGDRKISAVDRTLLHTEYVNGHLDEKGRDEVRLLKIFTKSIGVYGAEARTFGFSGYLCELLVIRFRSFENVIRYFSKAKGRVLIDPDERFRDPMLLIDPVDP

http://purl.uniprot.org/uniprot/Q9V302#attribution-D688308B634744D14F138DDA04EF1955
manual: true
evidence: ECO_0000255
source: MF_01264

Q97CI4
type: Protein
reviewed: true
created: 2005-08-16
modified: 2023-02-22
version: 111
mnemonic: CCA_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP28A10AA6E75F6643
alternative name: SIPFD662999492C3B2C
alternative name: SIP6045763066331F64
alternative name: SIP8E12E33E3E46AA42
alternative name: SIP94C33CD9C198DAE5
alternative name: SIP54E14E5A68BDE348
enzyme: http://purl.uniprot.org/enzyme/2.7.7.72
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP718F032687479A0E
annotation: SIP3E1A4839526E47C6
annotation: SIPEF599763F608ED73
annotation: SIP9AFAFC7778F4E953
annotation: SIP76C96372B5304D85
annotation: SIP040D8FF96C900216
annotation: PRO_0000139087
annotation: SIP69D94F371AD77707
annotation: SIP434869DE43D57331
annotation: SIP6260514EA2CE6D1A
annotation: SIPCCC1ED45ED43FC5A
annotation: SIP3687BF9C92D74BD4
annotation: SIP0ED8AD4D2701FAD8
annotation: SIP6F3D09BC94A06D28
annotation: SIP625D77712189D348
annotation: SIPAF8466C64172106C
annotation: SIPC401F7E290F6D193
annotation: SIP2618B2B54382A2AF
annotation: SIPAA0C8513C02286B8
annotation: SIP20FA79DCE36A8DDF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/692
classified with: http://purl.uniprot.org/keywords/694
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005524
classified with: GO_0004810
classified with: GO_0000287
classified with: GO_0000049
classified with: GO_0042245
classified with: GO_0001680
sequence: Q97CI4-1
proteome: Chromosome

Q97CI4-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP28A10AA6E75F6643
type: Structured Name
full name: CCA-adding enzyme
ec name: 2.7.7.72

SIPFD662999492C3B2C
type: Structured Name
full name: CCA tRNA nucleotidyltransferase

SIP6045763066331F64
type: Structured Name
full name: tRNA CCA-pyrophosphorylase

SIP8E12E33E3E46AA42
type: Structured Name
full name: tRNA adenylyl-/cytidylyl- transferase

SIP94C33CD9C198DAE5
type: Structured Name
full name: tRNA nucleotidyltransferase

SIP54E14E5A68BDE348
type: Structured Name
full name: tRNA-NT

cca
type: Gene
locus name: TV0117
orf name: TVG0124714

SIP718F032687479A0E
type: Function Annotation
comment: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.

SIP9AFAFC7778F4E953
type: Subunit Annotation
comment: Homodimer.

SIP76C96372B5304D85
type: Annotation
comment: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.

SIP040D8FF96C900216
type: Similarity Annotation
comment: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.

PRO_0000139087
type: Chain Annotation
comment: CCA-adding enzyme
mass: 50283
range: 22862382628418606tt1tt437

22862382628418606tt1
type: Position
type: ExactPosition
position: 1
reference: Q97CI4-1

22862382628418606tt437
type: Position
type: ExactPosition
position: 437
reference: Q97CI4-1

22862382628418606tt50
type: Position
type: ExactPosition
position: 50
reference: Q97CI4-1

22862382628418606tt53
type: Position
type: ExactPosition
position: 53
reference: Q97CI4-1

22862382628418606tt61
type: Position
type: ExactPosition
position: 61
reference: Q97CI4-1

22862382628418606tt63
type: Position
type: ExactPosition
position: 63
reference: Q97CI4-1

22862382628418606tt112
type: Position
type: ExactPosition
position: 112
reference: Q97CI4-1

22862382628418606tt135
type: Position
type: ExactPosition
position: 135
reference: Q97CI4-1

22862382628418606tt155
type: Position
type: ExactPosition
position: 155
reference: Q97CI4-1

22862382628418606tt164
type: Position
type: ExactPosition
position: 164
reference: Q97CI4-1

Q97CI4-1
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 50283
value: MIDYSAILNRYRPDEQELQKLKSISEYLTTRASEICRHKNIRADPVLVGSYAKGTNLKDGDLDLFIAFDRDYEEKIMEKLGLSIGHDLLPNGKEKYAEHPYVSGEIDGIKIDVVPCFKMEFGQKKISAVDRTLLHTRYVNEKLDGASKDQVRLLKVFMKSVGVYGAEARTYGFSGYLCELLIIRYGNFENVLRLFSTTRGRLKIDDDERFEDPMVLIDPVDPDRNVASAVSLESLSRMRIASKMFLDNPSESFFDLERKPIKPKYHDRGTCIRIYSIEKPDLTDDVLYPQIYKFKLALLRLMEEYNMEPVGSAIDVADRIYVLIETRKFISDSIRIHVGPPADTSNSIDFIKKWLTRERSRGPYLVGNRLYVDTVEERKTPEEIVLSNISKYSIGKNLDKLKNTIKVQKFEEIKGRIRVLDRFFSEEAFGGLNSLSA

http://purl.uniprot.org/uniprot/Q97CI4#attribution-D688308B634744D14F138DDA04EF1955
manual: true
evidence: ECO_0000255
source: MF_01264

Q9HKZ2
type: Protein
reviewed: true
created: 2013-04-03
modified: 2023-02-22
version: 117
mnemonic: CDC61_THEAC
citation: http://purl.uniprot.org/citations/11029001
citation: http://purl.uniprot.org/citations/17108356
citation: http://purl.uniprot.org/citations/18757887
recommended name: SIP2B5CD5BBFB515DE5
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP06067555000C79EA
annotation: SIP5992E0767BD3FFA8
annotation: PRO_0000421877
annotation: SIP10FB3FD105AE21D2
annotation: SIP6FE4FE6344B2F7A5
annotation: SIPA44079B586F5841B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0006260
sequence: Q9HKZ2-1
proteome: Chromosome

Q9HKZ2-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

Q9HKZ2-citation-17108356
type: Citation Statement
scope: FUNCTION
scope: GENE NAME

Q9HKZ2-citation-18757887
type: Citation Statement
scope: FUNCTION

arCOG00467
type: Resource
database: eggNOG
comment: Archaea

cd00009
type: Resource
database: CDD
comment: AAA
signature sequence match: CDD cd00009 match 1

http://purl.uniprot.org/gene3d/1.10.10.10
type: Resource
database: Gene3D
comment: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
signature sequence match: Gene3D 1.10.10.10 match 1

IPR003593
type: Resource
database: InterPro
comment: AAA+_ATPase

IPR036388
type: Resource
database: InterPro
comment: WH-like_DNA-bd_sf

PTHR10763
type: Resource
database: PANTHER
comment: CELL DIVISION CONTROL PROTEIN 6-RELATED
signature sequence match: PANTHER PTHR10763 match 1

PTHR10763:SF31
type: Resource
database: PANTHER
comment: ORC1-TYPE DNA REPLICATION PROTEIN 2
signature sequence match: PANTHER PTHR10763:SF31 match 1

PF13401
type: Resource
database: Pfam
comment: AAA_22
signature sequence match: Pfam PF13401 match 1

SM00382
type: Resource
database: SMART
comment: AAA
signature sequence match: SMART SM00382 match 1
signature sequence match: SMART SM00382 match 2

SIP2B5CD5BBFB515DE5
type: Structured Name
full name: Putative ORC1-type DNA replication protein 1

cdc6-1
type: Gene
locus name: Ta0451

SIP06067555000C79EA
type: Function Annotation
comment: Involved in regulation of DNA replication (By similarity). Has no effect on MCM helicase activity, either stimulatory or inhibitory. Does not bind DNA.

SIP5992E0767BD3FFA8
type: Similarity Annotation
comment: Belongs to the CDC6/cdc18 family.

PRO_0000421877
type: Chain Annotation
comment: Putative ORC1-type DNA replication protein 1
mass: 39110
range: 22862455778193966tt1tt347

22862455778193966tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKZ2-1

22862455778193966tt347
type: Position
type: ExactPosition
position: 347
reference: Q9HKZ2-1

22862455778193966tt34
type: Position
type: ExactPosition
position: 34
reference: Q9HKZ2-1

22862455778193966tt38
type: Position
type: ExactPosition
position: 38
reference: Q9HKZ2-1

22862455778193966tt167
type: Position
type: ExactPosition
position: 167
reference: Q9HKZ2-1

22862455778193966tt179
type: Position
type: ExactPosition
position: 179
reference: Q9HKZ2-1

Q9HKZ2-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 39110
value: MARDGEIERIMETVIKPTKNGITTNLILYGDSGTGKTVTMRYLAREIRDPQVVYVNAIAYRYVKNVLIDFLSKFGIIVPERSSYASLFTRIEGLLRNQGKNVILVIDEAANILKGDYDGLYYLFRSKDSFDVNISTIFVVMEDPAILFDAKIRKSYGIFSEIKFRRYTKGEIYQIVMNRAVQSLTGEGYDEDVLDYIAEVSAEYGSARVGIDILAKAAHIAEYRRSPKISFDDVRAARSMISPFVTESKLASMDYEDLMVLLSICRCLSASRFTDVDCISRNLSVISEQYGKKDINLYDRIKRLENNGIISSSIEGQGRGEGVKKVISIYDIPVSVLTEKIENLLSA

http://purl.uniprot.org/uniprot/Q9HKZ2#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q9HKZ2#attribution-A2180EEF70F0D062FEA3EC20EEB05A0D
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/17108356

http://purl.uniprot.org/uniprot/Q9HKZ2#attribution-D4E72D67E860409B10D3264075F37C88
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/18757887

http://purl.uniprot.org/uniprot/Q9HKZ2#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q9HKG3
type: Protein
reviewed: true
created: 2002-09-19
modified: 2023-02-22
version: 110
mnemonic: CDC62_THEAC
old mnemonic: CDC6_THEAC
citation: http://purl.uniprot.org/citations/11029001
citation: http://purl.uniprot.org/citations/17108356
citation: http://purl.uniprot.org/citations/18757887
recommended name: SIP362FAE978BEDE5B9
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIPE3A043E65D0DD979
annotation: SIPC6896421AF6B136C
annotation: SIPBF8459F5387CE4EA
annotation: SIP7EF1CD518E6F81F8
annotation: PRO_0000151024
annotation: SIP65C7D389D700453E
annotation: SIPECA0DB6A08BCBAE3
annotation: SIP8F45334682B014B1
annotation: SIP3C47043225C943B4
annotation: SIPC670677CD1782DCB
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0006260
sequence: Q9HKG3-1
proteome: Chromosome

Q9HKG3-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

Q9HKG3-citation-17108356
type: Citation Statement
scope: FUNCTION
scope: INTERACTION WITH MCM
scope: GENE NAME

Q9HKG3-citation-18757887
type: Citation Statement
scope: FUNCTION
scope: INTERACTION WITH MCM
scope: DOMAIN
scope: MUTAGENESIS OF LYS-66 AND ASP-143

cd08768
type: Resource
database: CDD
comment: Cdc6_C
signature sequence match: CDD cd08768 match 1

MF_01407
type: Resource
database: HAMAP
comment: ORC1_type_DNA_replic_protein
signature sequence match: HAMAP MF 01407 match 1

IPR015163
type: Resource
database: InterPro
comment: Cdc6_C

IPR014277
type: Resource
database: InterPro
comment: Orc1/Cdc6_arc

IPR036390
type: Resource
database: InterPro
comment: WH_DNA-bd_sf

PTHR10763:SF26
type: Resource
database: PANTHER
comment: CELL DIVISION CONTROL PROTEIN 6 HOMOLOG
signature sequence match: PANTHER PTHR10763:SF26 match 1

PF09079
type: Resource
database: Pfam
comment: Cdc6_C
signature sequence match: Pfam PF09079 match 1

SM01074
type: Resource
database: SMART
comment: Cdc6_C
signature sequence match: SMART SM01074 match 1

SSF46785
type: Resource
database: SUPFAM
comment: Winged helix' DNA-binding domain
signature sequence match: SUPFAM SSF46785 match 1

TIGR02928
type: Resource
database: TIGRFAMs
comment: orc1/cdc6 family replication initiation protein
signature sequence match: TIGRFAMs TIGR02928 match 1

SIP362FAE978BEDE5B9
type: Structured Name
full name: ORC1-type DNA replication protein 2

cdc6-2
type: Gene
locus name: Ta0636

SIPE3A043E65D0DD979
type: Function Annotation
comment: Involved in regulation of DNA replication. Stimulates the helicase activity of MCM via stimulation of its ATPase activity. Binding to MCM may result in conformational changes in MCM, leading to catalytic ATP hydrolysis by the helicase. Directly stimulates MCM movement along single-stranded and double-stranded DNA. Does not bind DNA.

SIPC6896421AF6B136C
type: Subunit Annotation
comment: Interacts with MCM.

SIPBF8459F5387CE4EA
type: Domain Annotation
comment: The N-terminal AAA+ ATPase domain and the C-terminal winged-helix (WH) domain are both required for stimulation of MCM activity.

SIP7EF1CD518E6F81F8
type: Similarity Annotation
comment: Belongs to the CDC6/cdc18 family.

PRO_0000151024
type: Chain Annotation
comment: ORC1-type DNA replication protein 2
mass: 45639
range: 22862455776949038tt1tt404

22862455776949038tt1
type: Position
type: ExactPosition
position: 1
reference: Q9HKG3-1

22862455776949038tt404
type: Position
type: ExactPosition
position: 404
reference: Q9HKG3-1

22862455776949038tt64
type: Position
type: ExactPosition
position: 64
reference: Q9HKG3-1

22862455776949038tt68
type: Position
type: ExactPosition
position: 68
reference: Q9HKG3-1

22862455776949038tt205
type: Position
type: ExactPosition
position: 205
reference: Q9HKG3-1

22862455776949038tt217
type: Position
type: ExactPosition
position: 217
reference: Q9HKG3-1

SIP3C47043225C943B4
type: Mutagenesis Annotation
comment: Does not affect stimulation of helicase activity.
substitution: E
range: 22862455776949038tt66tt66

22862455776949038tt66
type: Position
type: ExactPosition
position: 66
reference: Q9HKG3-1

SIPC670677CD1782DCB
type: Mutagenesis Annotation
comment: Does not affect stimulation of helicase activity.
substitution: N
range: 22862455776949038tt143tt143

22862455776949038tt143
type: Position
type: ExactPosition
position: 143
reference: Q9HKG3-1

Q9HKG3-1
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 45639
value: MDNPFARFAGTRTIQANLSLLEENYVPDSFPHRENQINEMVTILSSIMRGSRPSNIIVYGKTGTGKTSTTKYVTKMLVEAASNVSVVYVNCEIYDSPYSILVAIANSAGEEKIPELGWPIDRIYRETVERVEKTGKFFIIILDEMDRLIKKNGGDSLYVLLKLMTDVDSVRVSMIGITNDTTVLENIDARIKSRLNQESIVFPPYNASEIRDIISSRLDKVLGPGVVDDTAINLCAAIGAQEHGDARKAIDLMRIAIEIAIRENRNKITENEIYEARERYEMNVLREAISTLPLHSKIVLLSAVVTQEIEPNSVITGEIYENYRRICDDLGFSPLSPRRISDLLTELADYGLLVMDDRNMGKYGRTRSFSVVHQAETIKKYLLEDENLSMFKSSKMPKQTRFDT

http://purl.uniprot.org/uniprot/Q9HKG3#attribution-84F8B6F775FE4F50541D2D0D4FF53335
manual: true
evidence: ECO_0000255
source: MF_01407

http://purl.uniprot.org/uniprot/Q9HKG3#attribution-A2180EEF70F0D062FEA3EC20EEB05A0D
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/17108356

http://purl.uniprot.org/uniprot/Q9HKG3#attribution-D4E72D67E860409B10D3264075F37C88
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/18757887

Q6KZL0
type: Protein
reviewed: true
created: 2005-02-15
modified: 2023-02-22
version: 107
mnemonic: CDC6_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP8A5E73E03FF36C20
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP922475BC6F10919D
annotation: SIPED19FA31871F8936
annotation: PRO_0000151010
annotation: SIPCFABB755F7DF5692
annotation: SIP050B192C99F33B06
annotation: SIPF51519EC848801CC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0006260
sequence: Q6KZL0-1
proteome: Chromosome

Q6KZL0-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

cd18139
type: Resource
database: CDD
comment: HLD_clamp_RarA
signature sequence match: CDD cd18139 match 1

SIP8A5E73E03FF36C20
type: Structured Name
full name: ORC1-type DNA replication protein

cdc6
type: Gene
locus name: PTO1257

SIP922475BC6F10919D
type: Function Annotation
comment: Involved in regulation of DNA replication.

SIPED19FA31871F8936
type: Similarity Annotation
comment: Belongs to the CDC6/cdc18 family.

PRO_0000151010
type: Chain Annotation
comment: ORC1-type DNA replication protein
mass: 46246
range: 22859170378952750tt1tt408

22859170378952750tt1
type: Position
type: ExactPosition
position: 1
reference: Q6KZL0-1

22859170378952750tt408
type: Position
type: ExactPosition
position: 408
reference: Q6KZL0-1

22859170378952750tt65
type: Position
type: ExactPosition
position: 65
reference: Q6KZL0-1

22859170378952750tt69
type: Position
type: ExactPosition
position: 69
reference: Q6KZL0-1

22859170378952750tt205
type: Position
type: ExactPosition
position: 205
reference: Q6KZL0-1

22859170378952750tt217
type: Position
type: ExactPosition
position: 217
reference: Q6KZL0-1

Q6KZL0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 46246
value: MDNPFIKYSRSDDYIIGNLKTLSSSYIPDNLPHREQQIELMARSLSSIMHGGIASNILLYGQSGSGKTSSAINVTNMLRSAAGDRVSIHYINCEIYDSHYSIMVHMVNSFIGEEQIPNLGLPFDRIYYELVKRIKSRNLYTLIILDEIDRLLSKNGSDSLYVILKLLGDTEGSIIGITNDSSFINKLDMRVRSRLNAESIIFTPYNADELRDILKFRINGVIKNGFIEDSAINLCAAIGAQEHGDARKAIELLRIAIEYCIRENRERVTIDDIYMARERFEMNILKESVKTLPIHSKMVLLSAILTQEVSSDIAVTGEIYENYKNICAEIGLQPLSTRRISDLMSSLDDLGLIVTTTRSMGRYGRTKLIKVSQPVAIKNYILEDENFKNFQGSRIVRQSKLRTNYDDI

http://purl.uniprot.org/uniprot/Q6KZL0#attribution-84F8B6F775FE4F50541D2D0D4FF53335
manual: true
evidence: ECO_0000255
source: MF_01407

Q97AP1
type: Protein
reviewed: true
created: 2002-09-19
modified: 2023-02-22
version: 113
mnemonic: CDC6_THEVO
citation: http://purl.uniprot.org/citations/11121031
conflicting sequence: SIP91D0C571BE75337C
recommended name: SIP8A5E73E03FF36C20
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIPAEC4D7B52A112FA8
annotation: SIP0FCD128DF96E3307
annotation: SIP63A98E7E03564318
annotation: PRO_0000151025
annotation: SIPD1ACC2FB74ED6748
annotation: SIP6CB3D2AD45057413
annotation: SIPDCCCD7A41F5C30DF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/235
classified with: GO_0005524
classified with: GO_0006260
sequence: Q97AP1-1
proteome: Chromosome

Q97AP1-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

EMBL BAB59911.1
comment: Different initiation.

PTHR10763:SF22
type: Resource
database: PANTHER
comment: ORC1-TYPE DNA REPLICATION PROTEIN
signature sequence match: PANTHER PTHR10763:SF22 match 1

SIP8A5E73E03FF36C20
type: Structured Name
full name: ORC1-type DNA replication protein

cdc6
type: Gene
locus name: TV0769
orf name: TVG0773033

SIPAEC4D7B52A112FA8
type: Function Annotation
comment: Involved in regulation of DNA replication.

SIP0FCD128DF96E3307
type: Similarity Annotation
comment: Belongs to the CDC6/cdc18 family.

SIP63A98E7E03564318
type: Erroneous Initiation Annotation
comment: Extended N-terminus.
conflicting sequence: SIP91D0C571BE75337C

PRO_0000151025
type: Chain Annotation
comment: ORC1-type DNA replication protein
mass: 45905
range: 22862382595322158tt1tt404

22862382595322158tt1
type: Position
type: ExactPosition
position: 1
reference: Q97AP1-1

22862382595322158tt404
type: Position
type: ExactPosition
position: 404
reference: Q97AP1-1

22862382595322158tt64
type: Position
type: ExactPosition
position: 64
reference: Q97AP1-1

22862382595322158tt68
type: Position
type: ExactPosition
position: 68
reference: Q97AP1-1

22862382595322158tt205
type: Position
type: ExactPosition
position: 205
reference: Q97AP1-1

22862382595322158tt217
type: Position
type: ExactPosition
position: 217
reference: Q97AP1-1

Q97AP1-1
type: Simple Sequence
modified: 2002-09-19
version: 2
mass: 45905
value: MDNPFSKFTNSRTIQADLSLLEENYIPDSFPHREKQINDMVTILSSIMRNSRPSNIIVYGKTGTGKTSTTKYVTRMLQEATSNVEVIYVNCEIYDSPYSILVYVANFAGGEKIPELGWPVDRIYREAVDRINGTGKFFVIVLDEMDRLIKKSGGDSLYVLLKLMTDVENVKVSMIGITNDTTLLENLDSRIKSRLNQESIVFPPYNATEIRDIIASRLEKVFGPGVVDDTAINLCAAIGAQEHGDARKAIDLMRIAIEIAIRENRLKVTEKEVYEARDKYEMNVMHEAINTLPIHSKIVLLSAIVTQEIEPNSVITGEIYENYRRICEDLGFTPLTPRRISDLLTELSDYGLIVVDERNMGKYGRTRGFSVVKEIETIKKYLMEDENLSMFKTSKMTKQARFDS

http://purl.uniprot.org/uniprot/Q97AP1#attribution-84F8B6F775FE4F50541D2D0D4FF53335
manual: true
evidence: ECO_0000255
source: MF_01407

http://purl.uniprot.org/uniprot/Q97AP1#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6L013
type: Protein
reviewed: true
created: 2007-08-21
modified: 2023-02-22
version: 79
mnemonic: CDPAS_PICTO
old mnemonic: Y1104_PICTO
citation: http://purl.uniprot.org/citations/15184674
recommended name: SIP15B71A375824424B
alternative name: SIPF7C3CBB19BFFFC3C
enzyme: http://purl.uniprot.org/enzyme/2.7.7.67
organism: http://purl.uniprot.org/taxonomy/263820
annotation: SIP28B579E2E2C26F82
annotation: SIP077FB14124213EFA
annotation: SIP9FFB1794FB2F46E4
annotation: SIPDC1EBFE223639864
annotation: SIP52BA216B6F4CF9CC
annotation: SIPC8B59B90DA7E5ED5
annotation: PRO_0000298284
annotation: SIPC5DDFDCDF3D5DCEE
annotation: SIP7B45CA3C295EB4A2
annotation: SIP86D5C6475DED9878
annotation: SIPA844E93F4DFABF7F
annotation: SIP824F3E5A5201D3DE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1003
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/594
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0043338
classified with: GO_0046474
sequence: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW
proteome: Chromosome

Q6L013-citation-15184674
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
type: Strain

arCOG04106
type: Resource
database: eggNOG
comment: Archaea

MF_01117
type: Resource
database: HAMAP
comment: CDP_archaeol_synth
signature sequence match: HAMAP MF 01117 match 1

IPR032690
type: Resource
database: InterPro
comment: CarS

IPR002726
type: Resource
database: InterPro
comment: CarS_archaea

PTHR39650
type: Resource
database: PANTHER
comment: CDP-ARCHAEOL SYNTHASE
signature sequence match: PANTHER PTHR39650 match 1

PTHR39650:SF1
type: Resource
database: PANTHER
comment: CDP-ARCHAEOL SYNTHASE
signature sequence match: PANTHER PTHR39650:SF1 match 1

PF01864
type: Resource
database: Pfam
comment: CarS-like
signature sequence match: Pfam PF01864 match 1

SIP15B71A375824424B
type: Structured Name
full name: CDP-archaeol synthase
ec name: 2.7.7.67

SIPF7C3CBB19BFFFC3C
type: Structured Name
full name: CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase

carS
type: Gene
locus name: PTO1104

SIP28B579E2E2C26F82
type: Function Annotation
comment: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

SIPC8B59B90DA7E5ED5
type: Similarity Annotation
comment: Belongs to the CDP-archaeol synthase family.

PRO_0000298284
type: Chain Annotation
comment: CDP-archaeol synthase
mass: 20277
range: 22859173967508270tt1tt184

22859173967508270tt1
type: Position
type: ExactPosition
position: 1
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt184
type: Position
type: ExactPosition
position: 184
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

SIPC5DDFDCDF3D5DCEE
type: Transmembrane Annotation
comment: Helical
range: 22859173967508270tt4tt24

22859173967508270tt4
type: Position
type: ExactPosition
position: 4
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt24
type: Position
type: ExactPosition
position: 24
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

SIP7B45CA3C295EB4A2
type: Transmembrane Annotation
comment: Helical
range: 22859173967508270tt54tt74

22859173967508270tt54
type: Position
type: ExactPosition
position: 54
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt74
type: Position
type: ExactPosition
position: 74
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

SIP86D5C6475DED9878
type: Transmembrane Annotation
comment: Helical
range: 22859173967508270tt86tt106

22859173967508270tt86
type: Position
type: ExactPosition
position: 86
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt106
type: Position
type: ExactPosition
position: 106
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

SIPA844E93F4DFABF7F
type: Transmembrane Annotation
comment: Helical
range: 22859173967508270tt122tt142

22859173967508270tt122
type: Position
type: ExactPosition
position: 122
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt142
type: Position
type: ExactPosition
position: 142
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

SIP824F3E5A5201D3DE
type: Transmembrane Annotation
comment: Helical
range: 22859173967508270tt145tt165

22859173967508270tt145
type: Position
type: ExactPosition
position: 145
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

22859173967508270tt165
type: Position
type: ExactPosition
position: 165
reference: MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW

MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 20277

http://purl.uniprot.org/uniprot/Q6L013#attribution-338441870557CD1C830B2B106B0EB5B8
manual: true
evidence: ECO_0000255
source: MF_01117

Q9HLW7
type: Protein
reviewed: true
created: 2003-11-21
modified: 2023-02-22
version: 90
mnemonic: CDPAS_THEAC
old mnemonic: Y107_THEAC
citation: http://purl.uniprot.org/citations/11029001
recommended name: SIP15B71A375824424B
alternative name: SIPF7C3CBB19BFFFC3C
enzyme: http://purl.uniprot.org/enzyme/2.7.7.67
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP2CC2F055A3D47474
annotation: SIPCC8A71277E3925A3
annotation: SIP029C23FBFAA7A188
annotation: SIP09ECA1B753CE0211
annotation: SIP8FD027227B462ADC
annotation: SIPB2EA297B45DA2B05
annotation: PRO_0000094182
annotation: SIPFEFCCC33E48826AC
annotation: SIP999A571B68578294
annotation: SIP21CE6E64D9A48B86
annotation: SIPF4F9E6E09FC84CB7
annotation: SIP8AB0AF86C7A3EFBE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1003
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/594
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0043338
classified with: GO_0046474
sequence: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW
proteome: Chromosome

Q9HLW7-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

SIP15B71A375824424B
type: Structured Name
full name: CDP-archaeol synthase
ec name: 2.7.7.67

SIPF7C3CBB19BFFFC3C
type: Structured Name
full name: CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase

carS
type: Gene
locus name: Ta0107

SIP2CC2F055A3D47474
type: Function Annotation
comment: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

SIPB2EA297B45DA2B05
type: Similarity Annotation
comment: Belongs to the CDP-archaeol synthase family.

PRO_0000094182
type: Chain Annotation
comment: CDP-archaeol synthase
mass: 19399
range: 22862455794775854tt1tt176

22862455794775854tt1
type: Position
type: ExactPosition
position: 1
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt176
type: Position
type: ExactPosition
position: 176
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

SIPFEFCCC33E48826AC
type: Transmembrane Annotation
comment: Helical
range: 22862455794775854tt4tt24

22862455794775854tt4
type: Position
type: ExactPosition
position: 4
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt24
type: Position
type: ExactPosition
position: 24
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

SIP999A571B68578294
type: Transmembrane Annotation
comment: Helical
range: 22862455794775854tt49tt69

22862455794775854tt49
type: Position
type: ExactPosition
position: 49
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt69
type: Position
type: ExactPosition
position: 69
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

SIP21CE6E64D9A48B86
type: Transmembrane Annotation
comment: Helical
range: 22862455794775854tt83tt103

22862455794775854tt83
type: Position
type: ExactPosition
position: 83
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt103
type: Position
type: ExactPosition
position: 103
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

SIPF4F9E6E09FC84CB7
type: Transmembrane Annotation
comment: Helical
range: 22862455794775854tt115tt135

22862455794775854tt115
type: Position
type: ExactPosition
position: 115
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt135
type: Position
type: ExactPosition
position: 135
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

SIP8AB0AF86C7A3EFBE
type: Transmembrane Annotation
comment: Helical
range: 22862455794775854tt138tt158

22862455794775854tt138
type: Position
type: ExactPosition
position: 138
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

22862455794775854tt158
type: Position
type: ExactPosition
position: 158
reference: MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW

MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW
type: Simple Sequence
modified: 2001-03-01
version: 1
mass: 19399

http://purl.uniprot.org/uniprot/Q9HLW7#attribution-338441870557CD1C830B2B106B0EB5B8
manual: true
evidence: ECO_0000255
source: MF_01117

Q97CB5
type: Protein
reviewed: true
created: 2003-11-21
modified: 2023-02-22
version: 88
mnemonic: CDPAS_THEVO
old mnemonic: Y187_THEVO
citation: http://purl.uniprot.org/citations/11121031
recommended name: SIP15B71A375824424B
alternative name: SIPF7C3CBB19BFFFC3C
enzyme: http://purl.uniprot.org/enzyme/2.7.7.67
organism: http://purl.uniprot.org/taxonomy/273116
annotation: SIP28559767549413CC
annotation: SIP3079E3C5E7E12C04
annotation: SIPCD35A32A102F82AE
annotation: SIP5CB04C5C126EBA73
annotation: SIPB720D887A72502B5
annotation: SIPD753606FD301B911
annotation: PRO_0000094183
annotation: SIP0D714B229BCE39D7
annotation: SIPEE3923128619F0A1
annotation: SIP0D58F0A2FDBB0978
annotation: SIPDEEA5A7D567993E4
annotation: SIPC4A438D149A909C4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1003
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/594
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0043338
classified with: GO_0046474
sequence: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW
proteome: Chromosome

Q97CB5-citation-11121031
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1
type: Strain

SIP15B71A375824424B
type: Structured Name
full name: CDP-archaeol synthase
ec name: 2.7.7.67

SIPF7C3CBB19BFFFC3C
type: Structured Name
full name: CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase

carS
type: Gene
locus name: TV0187
orf name: TVG0192666

SIP28559767549413CC
type: Function Annotation
comment: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

SIPD753606FD301B911
type: Similarity Annotation
comment: Belongs to the CDP-archaeol synthase family.

PRO_0000094183
type: Chain Annotation
comment: CDP-archaeol synthase
mass: 20032
range: 22862382627960110tt1tt183

22862382627960110tt1
type: Position
type: ExactPosition
position: 1
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt183
type: Position
type: ExactPosition
position: 183
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

SIP0D714B229BCE39D7
type: Transmembrane Annotation
comment: Helical
range: 22862382627960110tt11tt31

22862382627960110tt11
type: Position
type: ExactPosition
position: 11
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt31
type: Position
type: ExactPosition
position: 31
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

SIPEE3923128619F0A1
type: Transmembrane Annotation
comment: Helical
range: 22862382627960110tt60tt80

22862382627960110tt60
type: Position
type: ExactPosition
position: 60
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt80
type: Position
type: ExactPosition
position: 80
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

SIP0D58F0A2FDBB0978
type: Transmembrane Annotation
comment: Helical
range: 22862382627960110tt86tt106

22862382627960110tt86
type: Position
type: ExactPosition
position: 86
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt106
type: Position
type: ExactPosition
position: 106
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

SIPDEEA5A7D567993E4
type: Transmembrane Annotation
comment: Helical
range: 22862382627960110tt122tt142

22862382627960110tt122
type: Position
type: ExactPosition
position: 122
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt142
type: Position
type: ExactPosition
position: 142
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

SIPC4A438D149A909C4
type: Transmembrane Annotation
comment: Helical
range: 22862382627960110tt145tt165

22862382627960110tt145
type: Position
type: ExactPosition
position: 145
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

22862382627960110tt165
type: Position
type: ExactPosition
position: 165
reference: MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW

MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW
type: Simple Sequence
modified: 2001-10-01
version: 1
mass: 20032

http://purl.uniprot.org/uniprot/Q97CB5#attribution-338441870557CD1C830B2B106B0EB5B8
manual: true
evidence: ECO_0000255
source: MF_01117

P21553
type: Protein
reviewed: true
created: 1991-05-01
modified: 2023-02-22
version: 136
mnemonic: CISY_THEAC
citation: http://purl.uniprot.org/citations/2269303
citation: http://purl.uniprot.org/citations/11029001
citation: SIPB85E65D031CFF99A
citation: http://purl.uniprot.org/citations/7704526
recommended name: SIP0CC0E185EA58BFB7
enzyme: http://purl.uniprot.org/enzyme/2.3.3.16
organism: http://purl.uniprot.org/taxonomy/273075
annotation: SIP7DE02BB7BC1C929B
annotation: SIP290D81ADDE9EB874
annotation: SIP18B5458D028658A5
annotation: SIPB8A6772161D676AA
annotation: SIPFEDB3CA69536E5ED
annotation: SIP520C045D7E321C24
annotation: SIP13EDDD09A84B4FE3
annotation: PRO_0000169978
annotation: SIPD0A89F672D96F7F7
annotation: SIP0DF905C3A42742B9
annotation: SIP89C17A4B664836DD
annotation: SIP451BE972A5458E5F
annotation: SIPF50AB5759AFDC633
annotation: SIPF9FE9AABC12EC626
annotation: SIPE40804E142768AB4
annotation: SIP3738A60B72CB2763
annotation: SIP1D44161DD677F396
annotation: SIPB6B38D07C8A55C78
annotation: SIP2B172C1A30D4AE06
annotation: SIP95DC83CBE654DC75
annotation: SIPC6DF1895FBB291C3
annotation: SIPE87B594C8B8213CC
annotation: SIPD4CCC8F4437F34BF
annotation: SIPDEBB5A98C0357B72
annotation: SIPB7A01A6DA9091F92
annotation: SIPB84048A5557E5F77
annotation: SIP5A5A42AC3E270370
annotation: SIP3AFAFB1A2BCB40F2
annotation: SIP8041D257A16B23EE
annotation: SIP7603F5E6F23427A3
annotation: SIP89D0CBF80597BB71
annotation: SIPDB0C3A26159B1E21
annotation: SIP56937290E949E05D
annotation: SIP63C5EB4CE4D57DEB
annotation: SIPBBDF4362B3E9F9C6
annotation: SIPF098BEB8E5AFD0BB
annotation: SIP25FCCE3A441924EF
annotation: SIPBF18E6F1CAB123B9
annotation: SIP1F22A6BF4F8EFEF3
annotation: SIP267E4CE3C7ACD329
annotation: SIPAE4884E713A8AD6D
annotation: SIPA1985AEE8267138D
annotation: SIP16F474A1A30FFA7A
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/21
classified with: http://purl.uniprot.org/keywords/903
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/816
classified with: GO_0005737
classified with: GO_0036440
classified with: GO_0006099
sequence: P21553-1
proteome: Chromosome

P21553-citation-2269303
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165
type: Strain

P21553-citation-11029001
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

P21553-citation-SIPB85E65D031CFF99A
type: Citation Statement
scope: PROTEIN SEQUENCE OF 2-17

P21553-citation-7704526
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
scope: ACTIVE SITE

S13831
type: Resource
database: PIR
comment: YKYT

2IFC
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.70
chain sequence mapping: PDB 2IFC tt1tt385

PDB 2IFC tt1tt385
chain: A/B/C/D=1-385

2R26
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.50
chain sequence mapping: PDB 2R26 tt2tt385

PDB 2R26 tt2tt385
chain: A/B/C/D=2-385

2R9E
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 1.95
chain sequence mapping: PDB 2R9E tt1tt385

PDB 2R9E tt1tt385
chain: A/B/C/D=1-385

4YBO
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.18
chain sequence mapping: PDB 4YBO tt2tt385

PDB 4YBO tt2tt385
chain: A/B/C/D=2-385

arCOG04237
type: Resource
database: eggNOG
comment: Archaea

http://purl.uniprot.org/brenda/2.3.3.16
type: Resource
database: BRENDA
comment: 6324

cd06118
type: Resource
database: CDD
comment: citrate_synt_like_1
signature sequence match: CDD cd06118 match 1

http://purl.uniprot.org/gene3d/1.10.580.10
type: Resource
database: Gene3D
comment: Citrate Synthase, domain 1
signature sequence match: Gene3D 1.10.580.10 match 1

http://purl.uniprot.org/gene3d/1.10.230.10
type: Resource
database: Gene3D
comment: Cytochrome P450-Terp, domain 2
signature sequence match: Gene3D 1.10.230.10 match 1

IPR011278
type: Resource
database: InterPro
comment: 2-MeCitrate/Citrate_synth_II

IPR016142
type: Resource
database: InterPro
comment: Citrate_synth-like_lrg_a-sub

IPR016143
type: Resource
database: InterPro
comment: Citrate_synth-like_sm_a-sub

IPR002020
type: Resource
database: InterPro
comment: Citrate_synthase

IPR019810
type: Resource
database: InterPro
comment: Citrate_synthase_AS

IPR024176
type: Resource
database: InterPro
comment: Citrate_synthase_bac-typ

IPR036969
type: Resource
database: InterPro
comment: Citrate_synthase_sf

PTHR42871
type: Resource
database: PANTHER
comment: CITRATE SYNTHASE
signature sequence match: PANTHER PTHR42871 match 1

PTHR42871:SF1
type: Resource
database: PANTHER
comment: CITRATE SYNTHASE
signature sequence match: PANTHER PTHR42871:SF1 match 1

PF00285
type: Resource
database: Pfam
comment: Citrate_synt
signature sequence match: Pfam PF00285 match 1

PIRSF001369
type: Resource
database: PIRSF
comment: Citrate_synth
signature sequence match: PIRSF PIRSF001369 match 1

PR00143
type: Resource
database: PRINTS
comment: CITRTSNTHASE

SSF48256
type: Resource
database: SUPFAM
comment: Citrate synthase
signature sequence match: SUPFAM SSF48256 match 1

TIGR01800
type: Resource
database: TIGRFAMs
comment: cit_synth_II
signature sequence match: TIGRFAMs TIGR01800 match 1

PS00480
type: Resource
database: PROSITE
comment: CITRATE_SYNTHASE
signature sequence match: PROSITE PS00480 match 1

SIP0CC0E185EA58BFB7
type: Structured Name
full name: Citrate synthase
ec name: 2.3.3.16

gltA
type: Gene
locus name: Ta0169

SIP290D81ADDE9EB874
type: Activity Regulation Annotation
comment: Allosterically inhibited by NADH.

SIPB8A6772161D676AA
type: Subunit Annotation
comment: Homodimer.

SIPFEDB3CA69536E5ED
type: Annotation
comment: Citrate synthase is found in nearly all cells capable of oxidative metabolism.

SIP520C045D7E321C24
type: Similarity Annotation
comment: Belongs to the citrate synthase family.

SIP13EDDD09A84B4FE3
type: Initiator Methionine Annotation
comment: Removed
range: 22573185064317742tt1tt1

22573185064317742tt1
type: Position
type: ExactPosition
position: 1
reference: P21553-1

PRO_0000169978
type: Chain Annotation
comment: Citrate synthase
mass: 42941
range: 22573185064317742tt2tt385

22573185064317742tt2
type: Position
type: ExactPosition
position: 2
reference: P21553-1

22573185064317742tt385
type: Position
type: ExactPosition
position: 385
reference: P21553-1

22573185064317742tt223
type: Position
type: ExactPosition
position: 223
reference: P21553-1

22573185064317742tt263
type: Position
type: ExactPosition
position: 263
reference: P21553-1

22573185064317742tt318
type: Position
type: ExactPosition
position: 318
reference: P21553-1

22573185064317742tt9
type: Position
type: ExactPosition
position: 9
reference: P21553-1

22573185064317742tt11
type: Position
type: ExactPosition
position: 11
reference: P21553-1

22573185064317742tt15
type: Position
type: ExactPosition
position: 15
reference: P21553-1

22573185064317742tt25
type: Position
type: ExactPosition
position: 25
reference: P21553-1

22573185064317742tt26
type: Position
type: ExactPosition
position: 26
reference: P21553-1

22573185064317742tt29
type: Position
type: ExactPosition
position: 29
reference: P21553-1

22573185064317742tt30
type: Position
type: ExactPosition
position: 30
reference: P21553-1

22573185064317742tt33
type: Position
type: ExactPosition
position: 33
reference: P21553-1

22573185064317742tt38
type: Position
type: ExactPosition
position: 38
reference: P21553-1

22573185064317742tt43
type: Position
type: ExactPosition
position: 43
reference: P21553-1

22573185064317742tt48
type: Position
type: ExactPosition
position: 48
reference: P21553-1

22573185064317742tt57
type: Position
type: ExactPosition
position: 57
reference: P21553-1

22573185064317742tt63
type: Position
type: ExactPosition
position: 63
reference: P21553-1

22573185064317742tt74
type: Position
type: ExactPosition
position: 74
reference: P21553-1

22573185064317742tt75
type: Position
type: ExactPosition
position: 75
reference: P21553-1

22573185064317742tt77
type: Position
type: ExactPosition
position: 77
reference: P21553-1

22573185064317742tt81
type: Position
type: ExactPosition
position: 81
reference: P21553-1

22573185064317742tt88
type: Position
type: ExactPosition
position: 88
reference: P21553-1

22573185064317742tt96
type: Position
type: ExactPosition
position: 96
reference: P21553-1

22573185064317742tt110
type: Position
type: ExactPosition
position: 110
reference: P21553-1

22573185064317742tt118
type: Position
type: ExactPosition
position: 118
reference: P21553-1

22573185064317742tt120
type: Position
type: ExactPosition
position: 120
reference: P21553-1

22573185064317742tt121
type: Position
type: ExactPosition
position: 121
reference: P21553-1

22573185064317742tt143
type: Position
type: ExactPosition
position: 143
reference: P21553-1

22573185064317742tt157
type: Position
type: ExactPosition
position: 157
reference: P21553-1

22573185064317742tt166
type: Position
type: ExactPosition
position: 166
reference: P21553-1

22573185064317742tt172
type: Position
type: ExactPosition
position: 172
reference: P21553-1

22573185064317742tt184
type: Position
type: ExactPosition
position: 184
reference: P21553-1

22573185064317742tt192
type: Position
type: ExactPosition
position: 192
reference: P21553-1

22573185064317742tt201
type: Position
type: ExactPosition
position: 201
reference: P21553-1

22573185064317742tt202
type: Position
type: ExactPosition
position: 202
reference: P21553-1

22573185064317742tt204
type: Position
type: ExactPosition
position: 204
reference: P21553-1

22573185064317742tt207
type: Position
type: ExactPosition
position: 207
reference: P21553-1

22573185064317742tt218
type: Position
type: ExactPosition
position: 218
reference: P21553-1

22573185064317742tt221
type: Position
type: ExactPosition
position: 221
reference: P21553-1

22573185064317742tt226
type: Position
type: ExactPosition
position: 226
reference: P21553-1

22573185064317742tt237
type: Position
type: ExactPosition
position: 237
reference: P21553-1

22573185064317742tt240
type: Position
type: ExactPosition
position: 240
reference: P21553-1

22573185064317742tt242
type: Position
type: ExactPosition
position: 242
reference: P21553-1

22573185064317742tt243
type: Position
type: ExactPosition
position: 243
reference: P21553-1

22573185064317742tt250
type: Position
type: ExactPosition
position: 250
reference: P21553-1

22573185064317742tt251
type: Position
type: ExactPosition
position: 251
reference: P21553-1

22573185064317742tt253
type: Position
type: ExactPosition
position: 253
reference: P21553-1