B5YIK7
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 79
mnemonic: ACCA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPD345ED6FED4C7897
enzyme: http://purl.uniprot.org/enzyme/2.1.3.15
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPCF1DD1FED625CBBD
annotation: SIPA349291EEFB111CE
annotation: SIPE7678ADBAA9F3E14
annotation: SIP210BBAA987E4FA95
annotation: SIP48294312481CD4A9
annotation: SIPEB0C4587B0684674
annotation: PRO_1000148757
annotation: SIP542C2BE6C15DE746
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0009317
classified with: GO_0003989
classified with: GO_0005524
classified with: GO_0016743
classified with: GO_0006633
classified with: GO_2001295
sequence: B5YIK7-1
proteome: Chromosome

SIPE9FD0B7DB3E0BCE1
type: Submission Citation
title: The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87.
author: Dodson R.J.
author: Durkin A.S.
author: Wu M.
author: Eisen J.
author: Sutton G.
date: 2008-08
submitted to: EMBL/GenBank/DDBJ

B5YIK7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0825
type: Resource
database: eggNOG
comment: Bacteria

MF_00823
type: Resource
database: HAMAP
comment: AcetylCoA_CT_alpha
signature sequence match: HAMAP MF 00823 match 1

IPR001095
type: Resource
database: InterPro
comment: Acetyl_CoA_COase_a_su

IPR029045
type: Resource
database: InterPro
comment: ClpP/crotonase-like_dom_sf

IPR011763
type: Resource
database: InterPro
comment: COA_CT_C

PTHR42853
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA
signature sequence match: PANTHER PTHR42853 match 1

PTHR42853:SF3
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA, CHLOROPLASTIC
signature sequence match: PANTHER PTHR42853:SF3 match 1

PF03255
type: Resource
database: Pfam
comment: ACCA
signature sequence match: Pfam PF03255 match 1

PR01069
type: Resource
database: PRINTS
comment: ACCCTRFRASEA

SSF52096
type: Resource
database: SUPFAM
comment: ClpP/crotonase
signature sequence match: SUPFAM SSF52096 match 1

TIGR00513
type: Resource
database: TIGRFAMs
comment: accA
signature sequence match: TIGRFAMs TIGR00513 match 1

PS50989
type: Resource
database: PROSITE
comment: COA_CT_CTER
signature sequence match: PROSITE PS50989 match 1

SIPD345ED6FED4C7897
type: Structured Name
full name: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
short name: ACCase subunit alpha
short name: Acetyl-CoA carboxylase carboxyltransferase subunit alpha
ec name: 2.1.3.15

accA
type: Gene
locus name: THEYE_A0319

SIPCF1DD1FED625CBBD
type: Function Annotation
comment: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.

SIP210BBAA987E4FA95
type: Subunit Annotation
comment: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).

SIPEB0C4587B0684674
type: Similarity Annotation
comment: Belongs to the AccA family.

PRO_1000148757
type: Chain Annotation
comment: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
mass: 36957
range: 18636006060930862tt1tt328

18636006060930862tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIK7-1

18636006060930862tt328
type: Position
type: ExactPosition
position: 328
reference: B5YIK7-1

SIP542C2BE6C15DE746
type: Domain Extent Annotation
comment: CoA carboxyltransferase C-terminal
range: 18636006060930862tt38tt297

18636006060930862tt38
type: Position
type: ExactPosition
position: 38
reference: B5YIK7-1

18636006060930862tt297
type: Position
type: ExactPosition
position: 297
reference: B5YIK7-1

B5YIK7-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 36957
value: MTYYLDFEKPIQELEIKIEELKKLSDGSDIDLTQEIKRLNKKLKELKTEVFSNLTPWQKTQIARHPERPYTLDYISIIFEDFIELHGDRRFGDDPAVIAGIGKIDGDPYALVGHQKGRTIKERIYRNFGQAHPEGYRKALRVMKLAEKFSIPVITMIDTPGAFPGIGAEERGQAEAIANNLMEMSLLKIPLIGFVIGEGGSGGALALSVCDKIFMLEHAIYSVISPEGCAAILWKKNSDVGVEDYMRAAEELKLTAQDLKKFGIIDDIISEPLGGAHREPQEVGKRIKAKIVSVATELIKIPPDELIKKRYEKFRKIGNFWGSSNRRK

http://purl.uniprot.org/uniprot/B5YIK7#attribution-59F6F4DF8DA7A0D31AA2B64E6869E9D5
manual: true
evidence: ECO_0000255
source: MF_00823

http://purl.uniprot.org/uniprot/B5YIK7#attribution-71DD31C3EAE9838607F06234F6539BBA
manual: true
evidence: ECO_0000255
source: PRU01137

B5YJG8
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 73
mnemonic: ACPS_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP2BEBC682D9C5D011
alternative name: SIP479C3A2215184A35
enzyme: http://purl.uniprot.org/enzyme/2.7.8.7
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPDC53D9032E659066
annotation: SIPC13CA4FB42C41876
annotation: SIP8E59D21203B95456
annotation: SIP6C65A85E1B95B680
annotation: SIP2247F5C13B77B6FD
annotation: PRO_1000093926
annotation: SIPDFCBAF0E62FA8B3A
annotation: SIPDE174C911D1F2190
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0008897
classified with: GO_0000287
classified with: GO_0006633
sequence: MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT
proteome: Chromosome

B5YJG8-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0736
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.90.470.20
type: Resource
database: Gene3D
comment: 4'-phosphopantetheinyl transferase domain
signature sequence match: Gene3D 3.90.470.20 match 1

MF_00101
type: Resource
database: HAMAP
comment: AcpS
signature sequence match: HAMAP MF 00101 match 1

IPR008278
type: Resource
database: InterPro
comment: 4-PPantetheinyl_Trfase_dom

IPR037143
type: Resource
database: InterPro
comment: 4-PPantetheinyl_Trfase_dom_sf

IPR002582
type: Resource
database: InterPro
comment: ACPS

IPR004568
type: Resource
database: InterPro
comment: Ppantetheine-prot_Trfase_dom

PF01648
type: Resource
database: Pfam
comment: ACPS
signature sequence match: Pfam PF01648 match 1

SSF56214
type: Resource
database: SUPFAM
comment: 4'-phosphopantetheinyl transferase
signature sequence match: SUPFAM SSF56214 match 1

TIGR00516
type: Resource
database: TIGRFAMs
comment: acpS
signature sequence match: TIGRFAMs TIGR00516 match 1

TIGR00556
type: Resource
database: TIGRFAMs
comment: pantethn_trn
signature sequence match: TIGRFAMs TIGR00556 match 1

SIP2BEBC682D9C5D011
type: Structured Name
full name: Holo-[acyl-carrier-protein] synthase
short name: Holo-ACP synthase
ec name: 2.7.8.7

SIP479C3A2215184A35
type: Structured Name
full name: 4'-phosphopantetheinyl transferase AcpS

acpS
type: Gene
locus name: THEYE_A0540

SIPDC53D9032E659066
type: Function Annotation
comment: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

SIP2247F5C13B77B6FD
type: Similarity Annotation
comment: Belongs to the P-Pant transferase superfamily. AcpS family.

PRO_1000093926
type: Chain Annotation
comment: Holo-[acyl-carrier-protein] synthase
mass: 12624
range: 18636006077446190tt1tt113

18636006077446190tt1
type: Position
type: ExactPosition
position: 1
reference: MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT

18636006077446190tt113
type: Position
type: ExactPosition
position: 113
reference: MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT

18636006077446190tt8
type: Position
type: ExactPosition
position: 8
reference: MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT

18636006077446190tt57
type: Position
type: ExactPosition
position: 57
reference: MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT

MIEGVGVDIVAVERIKKIYEKCGEKFLNKVFTEGEISYSFSHANPFPHLAARFAVKEAVIKALKKQKGLTLKNIEVRNNSDGSPEVKIPGFNKKIFISISHEKNYAVAFVVIT
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 12624

http://purl.uniprot.org/uniprot/B5YJG8#attribution-1F5F5386E209DFCC3422387253639116
manual: true
evidence: ECO_0000255
source: MF_00101

B5YIM9
type: Protein
reviewed: true
created: 2009-09-22
modified: 2023-02-22
version: 76
mnemonic: ALR_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPA9A4E98D933D1F32
enzyme: http://purl.uniprot.org/enzyme/5.1.1.1
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP83C6730C20CD0299
annotation: SIP89E0DCE6B07C6233
annotation: SIP456BE925C1F76EF9
annotation: SIP4ED8D91CE6BC6335
annotation: SIP8F202673F5336026
annotation: PRO_1000213843
annotation: SIP44DDEB20A4513347
annotation: SIP5C2A2D6814E6FB8E
annotation: SIP560D13F01C676DA1
annotation: SIP110FBF2B562D5698
annotation: SIPC1B46CCB637E6B5E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0008784
classified with: GO_0030170
classified with: GO_0030632
sequence: B5YIM9-1
proteome: Chromosome

B5YIM9-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0787
type: Resource
database: eggNOG
comment: Bacteria

cd00430
type: Resource
database: CDD
comment: PLPDE_III_AR
signature sequence match: CDD cd00430 match 1

http://purl.uniprot.org/gene3d/3.20.20.10
type: Resource
database: Gene3D
comment: Alanine racemase
signature sequence match: Gene3D 3.20.20.10 match 1

MF_01201
type: Resource
database: HAMAP
comment: Ala_racemase
signature sequence match: HAMAP MF 01201 match 1

IPR000821
type: Resource
database: InterPro
comment: Ala_racemase

IPR009006
type: Resource
database: InterPro
comment: Ala_racemase/Decarboxylase_C

IPR011079
type: Resource
database: InterPro
comment: Ala_racemase_C

IPR001608
type: Resource
database: InterPro
comment: Ala_racemase_N

IPR020622
type: Resource
database: InterPro
comment: Ala_racemase_pyridoxalP-BS

IPR029066
type: Resource
database: InterPro
comment: PLP-binding_barrel

PTHR30511
type: Resource
database: PANTHER
comment: ALANINE RACEMASE
signature sequence match: PANTHER PTHR30511 match 1

PTHR30511:SF0
type: Resource
database: PANTHER
comment: ALANINE RACEMASE, CATABOLIC-RELATED
signature sequence match: PANTHER PTHR30511:SF0 match 1

PF00842
type: Resource
database: Pfam
comment: Ala_racemase_C
signature sequence match: Pfam PF00842 match 1

PF01168
type: Resource
database: Pfam
comment: Ala_racemase_N
signature sequence match: Pfam PF01168 match 1

PR00992
type: Resource
database: PRINTS
comment: ALARACEMASE

SM01005
type: Resource
database: SMART
comment: Ala_racemase_C
signature sequence match: SMART SM01005 match 1

SSF50621
type: Resource
database: SUPFAM
comment: Alanine racemase C-terminal domain-like
signature sequence match: SUPFAM SSF50621 match 1

SSF51419
type: Resource
database: SUPFAM
comment: PLP-binding barrel
signature sequence match: SUPFAM SSF51419 match 1

TIGR00492
type: Resource
database: TIGRFAMs
comment: alr
signature sequence match: TIGRFAMs TIGR00492 match 1

PS00395
type: Resource
database: PROSITE
comment: ALANINE_RACEMASE
signature sequence match: PROSITE PS00395 match 1

SIPA9A4E98D933D1F32
type: Structured Name
full name: Alanine racemase
ec name: 5.1.1.1

alr
type: Gene
locus name: THEYE_A0341

SIP83C6730C20CD0299
type: Function Annotation
comment: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

SIP8F202673F5336026
type: Similarity Annotation
comment: Belongs to the alanine racemase family.

PRO_1000213843
type: Chain Annotation
comment: Alanine racemase
mass: 40664
range: 18636006061062446tt1tt363

18636006061062446tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIM9-1

18636006061062446tt363
type: Position
type: ExactPosition
position: 363
reference: B5YIM9-1

SIP44DDEB20A4513347
type: Active Site Annotation
comment: Proton acceptor; specific for D-alanine
range: 18636006061062446tt39tt39

18636006061062446tt39
type: Position
type: ExactPosition
position: 39
reference: B5YIM9-1

SIP5C2A2D6814E6FB8E
type: Active Site Annotation
comment: Proton acceptor; specific for L-alanine
range: 18636006061062446tt251tt251

18636006061062446tt251
type: Position
type: ExactPosition
position: 251
reference: B5YIM9-1

18636006061062446tt134
type: Position
type: ExactPosition
position: 134
reference: B5YIM9-1

18636006061062446tt299
type: Position
type: ExactPosition
position: 299
reference: B5YIM9-1

SIPC1B46CCB637E6B5E
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18636006061062446tt39tt39

substrate

B5YIM9-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 40664
value: MSRFLQAEINLKSLIHNFSKIKAHLRNTRVSCKIIAIVKADAYGHGAVEVARVFGLLGVDYLGVAFSEEAIVLREAGIKVPIIVLFDREIEGVFKYNLIPVIFDYRQAEFLSKEASRRGVILPVHIKVETGMGRLGIYENPCETIKKIAQLDNLKIDGVMSHFSRAEDLEWTQEQMKKFSKIREFLHNLGMKPLFHIANSQGLNYKEALFDAVRPGLMLYGYGAEGFIPCMTVKTKLLDIRKLPKGTPISYGGTFVTKKDSLIGVIPVGYADGYFRSLSNKAEVIVRGKRVPVVGTVCMDLTMIDLTDIQEVQIDDEVILLGKTGSEEITASHIAQWAGTIPYEVLTSFGGRARRKYIMEEEE

http://purl.uniprot.org/uniprot/B5YIM9#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YIM9#attribution-35F80A75CD326B6A74A2E2D4A39D726C
manual: true
evidence: ECO_0000255
source: MF_01201

B5YH68
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 79
mnemonic: AROA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPE1B0CBA292F34D12
annotation: SIP245E6A5105347092
annotation: SIP9B58A1FE4CC6FBC8
annotation: SIP3DC92FAFED92C4D3
annotation: SIP94EEBFF9CCE71624
annotation: SIPC493667CF72E4FD0
annotation: PRO_1000099762
annotation: SIP9A848BBDD00CBFE6
annotation: SIP1D90980C86E2FD8A
annotation: SIP23BAFBB67011859A
annotation: SIPA43C28184141FB91
annotation: SIPC06EB5F59C07641D
annotation: SIP16ADF57ECD4B9C2C
annotation: SIPBFC7B76478485943
annotation: SIP564A5C95CC3DC9B7
annotation: SIP7C356AD321B2CA71
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5YH68-1
proteome: Chromosome

B5YH68-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0128
type: Resource
database: eggNOG
comment: Bacteria

cd01556
type: Resource
database: CDD
comment: EPSP_synthase
signature sequence match: CDD cd01556 match 1

http://purl.uniprot.org/gene3d/3.65.10.10
type: Resource
database: Gene3D
comment: Enolpyruvate transferase domain
signature sequence match: Gene3D 3.65.10.10 match 1
signature sequence match: Gene3D 3.65.10.10 match 2

MF_00210
type: Resource
database: HAMAP
comment: EPSP_synth
signature sequence match: HAMAP MF 00210 match 1

IPR001986
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_dom

IPR036968
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_sf

IPR006264
type: Resource
database: InterPro
comment: EPSP_synthase

IPR023193
type: Resource
database: InterPro
comment: EPSP_synthase_CS

IPR013792
type: Resource
database: InterPro
comment: RNA3'P_cycl/enolpyr_Trfase_a/b

PTHR21090
type: Resource
database: PANTHER
comment: AROM/DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR21090 match 1

PTHR21090:SF5
type: Resource
database: PANTHER
comment: PENTAFUNCTIONAL AROM POLYPEPTIDE
signature sequence match: PANTHER PTHR21090:SF5 match 1

PF00275
type: Resource
database: Pfam
comment: EPSP_synthase
signature sequence match: Pfam PF00275 match 1

PIRSF000505
type: Resource
database: PIRSF
comment: EPSPS
signature sequence match: PIRSF PIRSF000505 match 1

SSF55205
type: Resource
database: SUPFAM
comment: EPT/RTPC-like
signature sequence match: SUPFAM SSF55205 match 1

TIGR01356
type: Resource
database: TIGRFAMs
comment: aroA
signature sequence match: TIGRFAMs TIGR01356 match 1

PS00104
type: Resource
database: PROSITE
comment: EPSP_SYNTHASE_1
signature sequence match: PROSITE PS00104 match 1

PS00885
type: Resource
database: PROSITE
comment: EPSP_SYNTHASE_2
signature sequence match: PROSITE PS00885 match 1

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: THEYE_A1767

SIPE1B0CBA292F34D12
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIP3DC92FAFED92C4D3
type: Subunit Annotation
comment: Monomer.

SIPC493667CF72E4FD0
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_1000099762
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 46959
range: 18636006042777646tt1tt430

18636006042777646tt1
type: Position
type: ExactPosition
position: 1
reference: B5YH68-1

18636006042777646tt430
type: Position
type: ExactPosition
position: 430
reference: B5YH68-1

SIP9A848BBDD00CBFE6
type: Region Annotation
comment: Phosphoenolpyruvate
range: 18636006042777646tt92tt95

18636006042777646tt92
type: Position
type: ExactPosition
position: 92
reference: B5YH68-1

18636006042777646tt95
type: Position
type: ExactPosition
position: 95
reference: B5YH68-1

SIP1D90980C86E2FD8A
type: Active Site Annotation
comment: Proton acceptor
range: 18636006042777646tt317tt317

18636006042777646tt317
type: Position
type: ExactPosition
position: 317
reference: B5YH68-1

SIP23BAFBB67011859A
type: Active Site Annotation
comment: Proton donor
range: 18636006042777646tt345tt345

18636006042777646tt345
type: Position
type: ExactPosition
position: 345
reference: B5YH68-1

18636006042777646tt21
type: Position
type: ExactPosition
position: 21
reference: B5YH68-1

18636006042777646tt22
type: Position
type: ExactPosition
position: 22
reference: B5YH68-1

18636006042777646tt26
type: Position
type: ExactPosition
position: 26
reference: B5YH68-1

18636006042777646tt122
type: Position
type: ExactPosition
position: 122
reference: B5YH68-1

18636006042777646tt344
type: Position
type: ExactPosition
position: 344
reference: B5YH68-1

18636006042777646tt348
type: Position
type: ExactPosition
position: 348
reference: B5YH68-1

18636006042777646tt390
type: Position
type: ExactPosition
position: 390
reference: B5YH68-1

B5YH68-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 46959
value: MNRIIKKAKTLKGEITPPPDKSISHRAVMFASLAKGQSRIKNFLWAKDPLSSLNAMKSLGVEITITDSKEIIVNGKGLHSLKESDNVIDCGNSGTTIRLLSGIVAGQRFLTVLTGDDSLRYRPMKRIINPLSLMGANIMGRAENKFPPIVIKGGFLKGISYEMPIASAQVKSAILLAGLYAKGETTLTEPHKSRDHTEKMLKNMGVNIIINDNTVKLSPVDHELNCFDITIPNDFSSAAFFIAGACLVPDSEILIKQVNLNETRTGFIEVLKNMGATIEIFNITEQGGEPVGDIFAKSSSELKGINVQGDIIPKLIDEFPILCVVATQAEGKTVIKDAKDLRAKESDRIKAMTSELKKMGVKIKEFEDGVEIEGPCKLIGTEVYSYKDHRIAMALSIAGVIAEGETTIKDANCVDISFPEFYSLLEMLQK

http://purl.uniprot.org/uniprot/B5YH68#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YH68#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

B5YHI4
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 80
mnemonic: AROB_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP63B1B84A81EF05E1
annotation: SIP08D81A2A7F2A6370
annotation: SIPA53BBA99C4B5E205
annotation: SIP64C734D9B029FFAD
annotation: SIP986D703888775C8B
annotation: SIPFA45BECCBF9E02DA
annotation: SIP286B5718489AA0F2
annotation: PRO_1000094649
annotation: SIPF464BA4B4BDC52CB
annotation: SIP40AE010ED37BEBC0
annotation: SIPC5F62540F9FB2954
annotation: SIP025CFBD8F296D7BE
annotation: SIPE9DF56635E191FAC
annotation: SIP4A9444960362C87A
annotation: SIP029FD68DBD0064FD
annotation: SIP0910C7887379A0ED
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5YHI4-1
proteome: Chromosome

B5YHI4-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0337
type: Resource
database: eggNOG
comment: Bacteria

cd08195
type: Resource
database: CDD
comment: DHQS
signature sequence match: CDD cd08195 match 1

http://purl.uniprot.org/gene3d/1.20.1090.10
type: Resource
database: Gene3D
comment: Dehydroquinate synthase-like - alpha domain
signature sequence match: Gene3D 1.20.1090.10 match 1

MF_00110
type: Resource
database: HAMAP
comment: DHQ_synthase
signature sequence match: HAMAP MF 00110 match 1

IPR016037
type: Resource
database: InterPro
comment: DHQ_synth_AroB

IPR030963
type: Resource
database: InterPro
comment: DHQ_synth_fam

IPR030960
type: Resource
database: InterPro
comment: DHQS/DOIS

PTHR43622
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR43622 match 1

PTHR43622:SF7
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC
signature sequence match: PANTHER PTHR43622:SF7 match 1

PF01761
type: Resource
database: Pfam
comment: DHQ_synthase
signature sequence match: Pfam PF01761 match 1

PIRSF001455
type: Resource
database: PIRSF
comment: DHQ_synth
signature sequence match: PIRSF PIRSF001455 match 1

SSF56796
type: Resource
database: SUPFAM
comment: Dehydroquinate synthase-like
signature sequence match: SUPFAM SSF56796 match 1

TIGR01357
type: Resource
database: TIGRFAMs
comment: aroB
signature sequence match: TIGRFAMs TIGR01357 match 1

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: THEYE_A0155

SIP63B1B84A81EF05E1
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIPA53BBA99C4B5E205
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIP286B5718489AA0F2
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_1000094649
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 40436
range: 18636006044021806tt1tt359

18636006044021806tt1
type: Position
type: ExactPosition
position: 1
reference: B5YHI4-1

18636006044021806tt359
type: Position
type: ExactPosition
position: 359
reference: B5YHI4-1

18636006044021806tt72
type: Position
type: ExactPosition
position: 72
reference: B5YHI4-1

18636006044021806tt77
type: Position
type: ExactPosition
position: 77
reference: B5YHI4-1

18636006044021806tt106
type: Position
type: ExactPosition
position: 106
reference: B5YHI4-1

18636006044021806tt110
type: Position
type: ExactPosition
position: 110
reference: B5YHI4-1

18636006044021806tt130
type: Position
type: ExactPosition
position: 130
reference: B5YHI4-1

18636006044021806tt131
type: Position
type: ExactPosition
position: 131
reference: B5YHI4-1

18636006044021806tt143
type: Position
type: ExactPosition
position: 143
reference: B5YHI4-1

18636006044021806tt152
type: Position
type: ExactPosition
position: 152
reference: B5YHI4-1

18636006044021806tt185
type: Position
type: ExactPosition
position: 185
reference: B5YHI4-1

18636006044021806tt248
type: Position
type: ExactPosition
position: 248
reference: B5YHI4-1

18636006044021806tt265
type: Position
type: ExactPosition
position: 265
reference: B5YHI4-1

B5YHI4-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 40436
value: MEKLRVELGERSYEILIDRGNLSLIGERLLRFSISKKIGIISNPKVSELYGQKVISSLQKEGFEPFVILIPDGEHYKDYFWAYHILTQLLEFGFDRGSFLIALGGGVIGDITGFVASIYMRGISYIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGTFWQPSLVWIDVDTLESLPEREFISGLAEVIKYGVIWDKEFFEFLEINRTKILKKDKDILISIIKRACEIKAEVVSKDERESALRAILNYGHTIGHAIETLTGYSSYLHGEAISIGMVHEAKLSSMLGFLDKEDFEKIRNILKEFGLPVNLPINMDSSAMLKTILLDKKNIEGKIRMVIPDSIGKMKINFEISGEDLKKVLNE

http://purl.uniprot.org/uniprot/B5YHI4#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YHI4#attribution-F61B7AC94BE0710BC96CCD11C1C2E895
manual: true
evidence: ECO_0000255
source: MF_00110

B5YH80
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 67
mnemonic: AROD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPDE3A72722C0C56D9
alternative name: SIP1653C78A2D211AC7
alternative name: SIPAFFD25EE9F4D710A
enzyme: http://purl.uniprot.org/enzyme/4.2.1.10
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPA2B98687A18713E9
annotation: SIPAA518CE4F6894060
annotation: SIP5023591681C013AF
annotation: SIPE32380877233FCB7
annotation: SIPCAAD0FB65B8FACDC
annotation: PRO_1000099925
annotation: SIP1C4181D7D86DAE02
annotation: SIPE3432F45E38F80C1
annotation: SIPF5518305C05E860B
annotation: SIPC6B8175A361E1870
annotation: SIPE05EC4852134758C
annotation: SIP9877B60C11FFAE39
annotation: SIP002D1C4A588C6709
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0003855
classified with: GO_0046279
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5YH80-1
proteome: Chromosome

B5YH80-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0710
type: Resource
database: eggNOG
comment: Bacteria

cd00502
type: Resource
database: CDD
comment: DHQase_I
signature sequence match: CDD cd00502 match 1

http://purl.uniprot.org/gene3d/3.20.20.70
type: Resource
database: Gene3D
comment: Aldolase class I
signature sequence match: Gene3D 3.20.20.70 match 1

MF_00214
type: Resource
database: HAMAP
comment: AroD
signature sequence match: HAMAP MF 00214 match 1

IPR018508
type: Resource
database: InterPro
comment: 3-dehydroquinate_DH_AS

IPR013785
type: Resource
database: InterPro
comment: Aldolase_TIM

IPR001381
type: Resource
database: InterPro
comment: DHquinase_I

PTHR43699
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE DEHYDRATASE
signature sequence match: PANTHER PTHR43699 match 1

PTHR43699:SF1
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE DEHYDRATASE
signature sequence match: PANTHER PTHR43699:SF1 match 1

PF01487
type: Resource
database: Pfam
comment: DHquinase_I
signature sequence match: Pfam PF01487 match 1

SSF51569
type: Resource
database: SUPFAM
comment: Aldolase
signature sequence match: SUPFAM SSF51569 match 1

TIGR01093
type: Resource
database: TIGRFAMs
comment: aroD
signature sequence match: TIGRFAMs TIGR01093 match 1

PS01028
type: Resource
database: PROSITE
comment: DEHYDROQUINASE_I
signature sequence match: PROSITE PS01028 match 1

SIPDE3A72722C0C56D9
type: Structured Name
full name: 3-dehydroquinate dehydratase
short name: 3-dehydroquinase
ec name: 4.2.1.10

SIP1653C78A2D211AC7
type: Structured Name
full name: Type I DHQase

SIPAFFD25EE9F4D710A
type: Structured Name
full name: Type I dehydroquinase
short name: DHQ1

aroD
type: Gene
locus name: THEYE_A1779

SIPA2B98687A18713E9
type: Function Annotation
comment: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

SIPE32380877233FCB7
type: Subunit Annotation
comment: Homodimer.

SIPCAAD0FB65B8FACDC
type: Similarity Annotation
comment: Belongs to the type-I 3-dehydroquinase family.

PRO_1000099925
type: Chain Annotation
comment: 3-dehydroquinate dehydratase
mass: 25842
range: 18636006042906670tt1tt226

18636006042906670tt1
type: Position
type: ExactPosition
position: 1
reference: B5YH80-1

18636006042906670tt226
type: Position
type: ExactPosition
position: 226
reference: B5YH80-1

SIP1C4181D7D86DAE02
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18636006042906670tt120tt120

18636006042906670tt120
type: Position
type: ExactPosition
position: 120
reference: B5YH80-1

SIPE3432F45E38F80C1
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 18636006042906670tt147tt147

18636006042906670tt147
type: Position
type: ExactPosition
position: 147
reference: B5YH80-1

18636006042906670tt33
type: Position
type: ExactPosition
position: 33
reference: B5YH80-1

18636006042906670tt35
type: Position
type: ExactPosition
position: 35
reference: B5YH80-1

18636006042906670tt65
type: Position
type: ExactPosition
position: 65
reference: B5YH80-1

18636006042906670tt186
type: Position
type: ExactPosition
position: 186
reference: B5YH80-1

18636006042906670tt205
type: Position
type: ExactPosition
position: 205
reference: B5YH80-1

18636006042906670tt209
type: Position
type: ExactPosition
position: 209
reference: B5YH80-1

B5YH80-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 25842
value: MLLQNIPAIAVVLKDKDVLSIPKEELKGADLIELRVDMFEKTENISDIFETAKRKYNLPLLCTIRLPEEGGKREIKNRVEIYQAVIPFCNFFDIEIFSNEAPFLRQLSIKNNITLIGSYHNFINTPSMEQLEEVFDRGKTMGMDIIKIATMVNEKKDIETLLYFTLRHKLDRIIVLGMGQKGIPSRIINPVFGSMITYASLNEISAPGQIHLKDMVHIFKVMGLRG

http://purl.uniprot.org/uniprot/B5YH80#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YH80#attribution-AA5D28B8D6D44CA4EFA21F42BFC7C935
manual: true
evidence: ECO_0000255
source: MF_00214

B5YJ55
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 86
mnemonic: AROE_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPBD1E1E110AD66A3E
enzyme: http://purl.uniprot.org/enzyme/1.1.1.25
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP524E48100809B139
annotation: SIPE6AA03DE90E76B93
annotation: SIP615D38F75CB4AA83
annotation: SIP19D02ACCBFF8C696
annotation: SIP608F9FCA32A95810
annotation: PRO_1000100150
annotation: SIP28614015B8FE93D9
annotation: SIPC83F2B0DF3CE8784
annotation: SIP45D8E50A8075A29B
annotation: SIP4197F3DF8AF7CDF2
annotation: SIPB1CDFB95F635290E
annotation: SIPD7A4D64E6264540B
annotation: SIP1CF4AB77ECA26D26
annotation: SIP8D46559D1455DE1B
annotation: SIP2E595A54D85B01F0
annotation: SIPB63C4D8945DC497D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0050661
classified with: GO_0004764
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
classified with: GO_0019632
sequence: B5YJ55-1
proteome: Chromosome

B5YJ55-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0169
type: Resource
database: eggNOG
comment: Bacteria

cd01065
type: Resource
database: CDD
comment: NAD_bind_Shikimate_DH
signature sequence match: CDD cd01065 match 1

http://purl.uniprot.org/gene3d/3.40.50.10860
type: Resource
database: Gene3D
comment: Leucine Dehydrogenase, chain A, domain 1
signature sequence match: Gene3D 3.40.50.10860 match 1

http://purl.uniprot.org/gene3d/3.40.50.720
type: Resource
database: Gene3D
comment: NAD(P)-binding Rossmann-like Domain
signature sequence match: Gene3D 3.40.50.720 match 1

MF_00222
type: Resource
database: HAMAP
comment: Shikimate_DH_AroE
signature sequence match: HAMAP MF 00222 match 1

IPR046346
type: Resource
database: InterPro
comment: Aminoacid_DH-like_N_sf

IPR036291
type: Resource
database: InterPro
comment: NAD(P)-bd_dom_sf

IPR041121
type: Resource
database: InterPro
comment: SDH_C

IPR011342
type: Resource
database: InterPro
comment: Shikimate_DH

IPR013708
type: Resource
database: InterPro
comment: Shikimate_DH-bd_N

IPR022893
type: Resource
database: InterPro
comment: Shikimate_DH_fam

IPR006151
type: Resource
database: InterPro
comment: Shikm_DH/Glu-tRNA_Rdtase

PTHR21089:SF1
type: Resource
database: PANTHER
comment: BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE/SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC
signature sequence match: PANTHER PTHR21089:SF1 match 1

PTHR21089
type: Resource
database: PANTHER
comment: SHIKIMATE DEHYDROGENASE
signature sequence match: PANTHER PTHR21089 match 1

PF18317
type: Resource
database: Pfam
comment: SDH_C
signature sequence match: Pfam PF18317 match 1

PF01488
type: Resource
database: Pfam
comment: Shikimate_DH
signature sequence match: Pfam PF01488 match 1

PF08501
type: Resource
database: Pfam
comment: Shikimate_dh_N
signature sequence match: Pfam PF08501 match 1

SSF53223
type: Resource
database: SUPFAM
comment: Aminoacid dehydrogenase-like, N-terminal domain
signature sequence match: SUPFAM SSF53223 match 1

SSF51735
type: Resource
database: SUPFAM
comment: NAD(P)-binding Rossmann-fold domains
signature sequence match: SUPFAM SSF51735 match 1

TIGR00507
type: Resource
database: TIGRFAMs
comment: aroE
signature sequence match: TIGRFAMs TIGR00507 match 1

SIPBD1E1E110AD66A3E
type: Structured Name
full name: Shikimate dehydrogenase (NADP(+))
short name: SDH
ec name: 1.1.1.25

aroE
type: Gene
locus name: THEYE_A0423

SIP524E48100809B139
type: Function Annotation
comment: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

SIP19D02ACCBFF8C696
type: Subunit Annotation
comment: Homodimer.

SIP608F9FCA32A95810
type: Similarity Annotation
comment: Belongs to the shikimate dehydrogenase family.

PRO_1000100150
type: Chain Annotation
comment: Shikimate dehydrogenase (NADP(+))
mass: 30561
range: 18636006076265774tt1tt275

18636006076265774tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJ55-1

18636006076265774tt275
type: Position
type: ExactPosition
position: 275
reference: B5YJ55-1

SIP28614015B8FE93D9
type: Active Site Annotation
comment: Proton acceptor
range: 18636006076265774tt70tt70

18636006076265774tt70
type: Position
type: ExactPosition
position: 70
reference: B5YJ55-1

18636006076265774tt19
type: Position
type: ExactPosition
position: 19
reference: B5YJ55-1

18636006076265774tt21
type: Position
type: ExactPosition
position: 21
reference: B5YJ55-1

18636006076265774tt66
type: Position
type: ExactPosition
position: 66
reference: B5YJ55-1

18636006076265774tt82
type: Position
type: ExactPosition
position: 82
reference: B5YJ55-1

18636006076265774tt91
type: Position
type: ExactPosition
position: 91
reference: B5YJ55-1

18636006076265774tt106
type: Position
type: ExactPosition
position: 106
reference: B5YJ55-1

18636006076265774tt130
type: Position
type: ExactPosition
position: 130
reference: B5YJ55-1

18636006076265774tt134
type: Position
type: ExactPosition
position: 134
reference: B5YJ55-1

18636006076265774tt218
type: Position
type: ExactPosition
position: 218
reference: B5YJ55-1

18636006076265774tt220
type: Position
type: ExactPosition
position: 220
reference: B5YJ55-1

18636006076265774tt239
type: Position
type: ExactPosition
position: 239
reference: B5YJ55-1

B5YJ55-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 30561
value: MITGKTKIIGIFGDPIEHTLSPLIHNEAFSYLGLDYCYVAFNVKKDKLKEAVEAIRALNIRGVNITVPHKETVIQYIDELSDEVKNIGAVNTILNNEGILKGFNTDVNGFILSLKDEGISMKNKNFLILGAGGAAKAIVYGILKEGGKVYIYNRTPSNALAIKEKFKKFGFIEIVEMDKSVTEKIDVIVNATSLGLKKDDPMPLNPELIKPEHVYCDIVYPETPLMREAERIGCKVVGGIGMLLWQAAFAFKIWTEVEAPIEIMKKTLNKLLTKD

http://purl.uniprot.org/uniprot/B5YJ55#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJ55#attribution-5C7F524C16633F113A12ABC5480D4824
manual: true
evidence: ECO_0000255
source: MF_00222

B5YHI3
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 73
mnemonic: AROK_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP6918AA3D5BEFE474
enzyme: http://purl.uniprot.org/enzyme/2.7.1.71
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP14BAA28785AF8475
annotation: SIP571A6682423DD09E
annotation: SIPDBA1A24B2AA004E9
annotation: SIP8EF7C2A1730EED05
annotation: SIP21A13D76C685B7A0
annotation: SIPB31AF705CBD09DFB
annotation: SIP46872780D477FC3D
annotation: PRO_1000094430
annotation: SIP99460583B3E65BED
annotation: SIP7B1C1EF8DFBABE6A
annotation: SIPB3E970FB8D5F6A80
annotation: SIPB14860163975BE62
annotation: SIPF4963BB97A95D3F7
annotation: SIPBF196400B11B1DF8
annotation: SIP151F87AF02A20E38
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0005524
classified with: GO_0000287
classified with: GO_0004765
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
classified with: GO_0016310
sequence: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT
proteome: Chromosome

B5YHI3-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0703
type: Resource
database: eggNOG
comment: Bacteria

cd00464
type: Resource
database: CDD
comment: SK
signature sequence match: CDD cd00464 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1
signature sequence match: Gene3D 3.40.50.300 match 2
signature sequence match: Gene3D 3.40.50.300 match 3

MF_00109
type: Resource
database: HAMAP
comment: Shikimate_kinase
signature sequence match: HAMAP MF 00109 match 1

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

IPR031322
type: Resource
database: InterPro
comment: Shikimate/glucono_kinase

IPR000623
type: Resource
database: InterPro
comment: Shikimate_kinase/TSH1

IPR023000
type: Resource
database: InterPro
comment: Shikimate_kinase_CS

PTHR21087
type: Resource
database: PANTHER
comment: SHIKIMATE KINASE
signature sequence match: PANTHER PTHR21087 match 1

PTHR21087:SF16
type: Resource
database: PANTHER
comment: SHIKIMATE KINASE 1, CHLOROPLASTIC
signature sequence match: PANTHER PTHR21087:SF16 match 1

PF01202
type: Resource
database: Pfam
comment: SKI
signature sequence match: Pfam PF01202 match 1

PR01100
type: Resource
database: PRINTS
comment: SHIKIMTKNASE

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1
signature sequence match: SUPFAM SSF52540 match 2

PS01128
type: Resource
database: PROSITE
comment: SHIKIMATE_KINASE
signature sequence match: PROSITE PS01128 match 1

SIP6918AA3D5BEFE474
type: Structured Name
full name: Shikimate kinase
short name: SK
ec name: 2.7.1.71

aroK
type: Gene
locus name: THEYE_A0154

SIP14BAA28785AF8475
type: Function Annotation
comment: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.

SIPDBA1A24B2AA004E9
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIP21A13D76C685B7A0
type: Subunit Annotation
comment: Monomer.

SIP46872780D477FC3D
type: Similarity Annotation
comment: Belongs to the shikimate kinase family.

PRO_1000094430
type: Chain Annotation
comment: Shikimate kinase
mass: 19773
range: 18636006044021550tt1tt173

18636006044021550tt1
type: Position
type: ExactPosition
position: 1
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt173
type: Position
type: ExactPosition
position: 173
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt11
type: Position
type: ExactPosition
position: 11
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt16
type: Position
type: ExactPosition
position: 16
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt15
type: Position
type: ExactPosition
position: 15
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt33
type: Position
type: ExactPosition
position: 33
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt57
type: Position
type: ExactPosition
position: 57
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt79
type: Position
type: ExactPosition
position: 79
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt117
type: Position
type: ExactPosition
position: 117
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

18636006044021550tt136
type: Position
type: ExactPosition
position: 136
reference: MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT

substrate

MKNIVLIGFMGTGKTSVGKLVAKKLGFDFVDVDEVIEKATGMEISEIFSKFGESRFRDIEEEMIKLITPKKRQVIATGGGVVLRDENMKRLKKDGVIFCLRASENVIFERLKQTTNRPLLQVENPEERIKELLQKRMPLYEKADFCIDTEGLTPEEVAEKIIKEYERLSNGKT
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 19773

http://purl.uniprot.org/uniprot/B5YHI3#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YHI3#attribution-721B6DCFEBB6A97B07CF9A0173E141ED
manual: true
evidence: ECO_0000255
source: MF_00109

B5YI22
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 85
mnemonic: ATPA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPBE7712CDD879D1B2
alternative name: SIP605D291825F99072
alternative name: SIPA3FE03A31043C3FE
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP3043113835A7FB14
annotation: SIPC31DBFCBB60D7DFF
annotation: SIPF985FD9634240913
annotation: SIP95B135C94BD7FA95
annotation: SIP86FBFB34C0310BDA
annotation: PRO_1000143450
annotation: SIP7C917293EC873BEB
annotation: SIPA9C659C10C0ED713
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0043531
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
classified with: GO_0015986
sequence: B5YI22-1
proteome: Chromosome

B5YI22-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0056
type: Resource
database: eggNOG
comment: Bacteria

cd18113
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_C
signature sequence match: CDD cd18113 match 1

cd18116
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_N
signature sequence match: CDD cd18116 match 1

cd01132
type: Resource
database: CDD
comment: F1-ATPase_alpha_CD
signature sequence match: CDD cd01132 match 1

http://purl.uniprot.org/gene3d/1.20.150.20
type: Resource
database: Gene3D
comment: ATP synthase alpha/beta chain, C-terminal domain
signature sequence match: Gene3D 1.20.150.20 match 1

MF_01346
type: Resource
database: HAMAP
comment: ATP_synth_alpha_bact
signature sequence match: HAMAP MF 01346 match 1

IPR023366
type: Resource
database: InterPro
comment: ATP_synth_asu-like_sf

IPR000793
type: Resource
database: InterPro
comment: ATP_synth_asu_C

IPR038376
type: Resource
database: InterPro
comment: ATP_synth_asu_C_sf

IPR033732
type: Resource
database: InterPro
comment: ATP_synth_F1_a_nt-bd_dom

IPR005294
type: Resource
database: InterPro
comment: ATP_synth_F1_asu

IPR020003
type: Resource
database: InterPro
comment: ATPase_a/bsu_AS

IPR004100
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N

IPR036121
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N_sf

IPR000194
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_nucl-bd

PTHR48082
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082 match 1

PTHR48082:SF2
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082:SF2 match 1

PF00006
type: Resource
database: Pfam
comment: ATP-synt_ab
signature sequence match: Pfam PF00006 match 1

PF00306
type: Resource
database: Pfam
comment: ATP-synt_ab_C
signature sequence match: Pfam PF00306 match 1

PF02874
type: Resource
database: Pfam
comment: ATP-synt_ab_N
signature sequence match: Pfam PF02874 match 1

PIRSF039088
type: Resource
database: PIRSF
comment: F_ATPase_subunit_alpha
signature sequence match: PIRSF PIRSF039088 match 1

SSF47917
type: Resource
database: SUPFAM
comment: C-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF47917 match 1

SSF50615
type: Resource
database: SUPFAM
comment: N-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF50615 match 1

TIGR00962
type: Resource
database: TIGRFAMs
comment: atpA
signature sequence match: TIGRFAMs TIGR00962 match 1

PS00152
type: Resource
database: PROSITE
comment: ATPASE_ALPHA_BETA
signature sequence match: PROSITE PS00152 match 1

SIPBE7712CDD879D1B2
type: Structured Name
full name: ATP synthase subunit alpha
ec name: 7.1.2.2

SIP605D291825F99072
type: Structured Name
full name: ATP synthase F1 sector subunit alpha

SIPA3FE03A31043C3FE
type: Structured Name
full name: F-ATPase subunit alpha

atpA
type: Gene
locus name: THEYE_A0239

SIP3043113835A7FB14
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

SIPF985FD9634240913
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP86FBFB34C0310BDA
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_1000143450
type: Chain Annotation
comment: ATP synthase subunit alpha
mass: 55204
range: 18636006059291182tt1tt502

18636006059291182tt1
type: Position
type: ExactPosition
position: 1
reference: B5YI22-1

18636006059291182tt502
type: Position
type: ExactPosition
position: 502
reference: B5YI22-1

18636006059291182tt169
type: Position
type: ExactPosition
position: 169
reference: B5YI22-1

18636006059291182tt176
type: Position
type: ExactPosition
position: 176
reference: B5YI22-1

SIPA9C659C10C0ED713
type: Site Annotation
comment: Required for activity
range: 18636006059291182tt362tt362

18636006059291182tt362
type: Position
type: ExactPosition
position: 362
reference: B5YI22-1

B5YI22-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 55204
value: MELKMEEISEYLKKQIADFEKKADVSEVGIVTSIGDGVARIYGLDNCMASEMLELPNGVYGMALNLEEDNVGAILFGDDRLVKEGDLVKRTGRVMETPVGEELIGRVVNAIGIPIDGKGPINAKTSRKVDVIAPGIIKRQPVKEPLQTGLKAIDAMIPIGRGQRELVIGDRQTGKTAILLDTIINQKGQNCICIYVACGQRRQSVVQVVETLKKYGAMDHTIVVAATASEPASMQYLAPYVGCAMGEYFRDKGMHALVCYDDLTKQAYAYRQVSLILRRPPGREAYPGDVFYLHSRLLERAAKLSDAEGGGSLTALPVIETQAGDVSGYIPTNVISITDGQIYLEPELFYAGVRPAINVGLSVSRVGGAAQIKAMKQVAGMLRLDLAQYRELAAFAQFAADLDKATRALLERGQRMVELLKQDQYVPMPVEDQIMLIFAGTQGHLDDLPVSAIKAFEQGFLSFIRSQKEDIRKEIREKKELDDTLKQKITDAILEFKKTFQP

http://purl.uniprot.org/uniprot/B5YI22#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI22#attribution-5C1C7D08C5C30A92BBCA3D89004F22BF
manual: true
evidence: ECO_0000255
source: MF_01346

B5YI24
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 80
mnemonic: ATPB_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPCABF2B7C796C67AF
alternative name: SIP54BDE05048B44533
alternative name: SIPE5DC476874342920
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP2666BB5A67A57CB3
annotation: SIPB2FB84797C0F8790
annotation: SIPBE048A669C61BF96
annotation: SIP5951A9366829ABFE
annotation: SIP67F165EBFF343A30
annotation: PRO_1000143558
annotation: SIP77D64E223FAB212F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: B5YI24-1
proteome: Chromosome

B5YI24-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0055
type: Resource
database: eggNOG
comment: Bacteria

cd18110
type: Resource
database: CDD
comment: ATP-synt_F1_beta_C
signature sequence match: CDD cd18110 match 1

cd18115
type: Resource
database: CDD
comment: ATP-synt_F1_beta_N
signature sequence match: CDD cd18115 match 1

cd01133
type: Resource
database: CDD
comment: F1-ATPase_beta_CD
signature sequence match: CDD cd01133 match 1

MF_01347
type: Resource
database: HAMAP
comment: ATP_synth_beta_bact
signature sequence match: HAMAP MF 01347 match 1

IPR003593
type: Resource
database: InterPro
comment: AAA+_ATPase

IPR005722
type: Resource
database: InterPro
comment: ATP_synth_F1_bsu

IPR024034
type: Resource
database: InterPro
comment: ATPase_F1/V1_b/a_C

PTHR15184
type: Resource
database: PANTHER
comment: ATP SYNTHASE
signature sequence match: PANTHER PTHR15184 match 1

PTHR15184:SF71
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR15184:SF71 match 1

SM00382
type: Resource
database: SMART
comment: AAA
signature sequence match: SMART SM00382 match 1

TIGR01039
type: Resource
database: TIGRFAMs
comment: atpD
signature sequence match: TIGRFAMs TIGR01039 match 1

SIPCABF2B7C796C67AF
type: Structured Name
full name: ATP synthase subunit beta
ec name: 7.1.2.2

SIP54BDE05048B44533
type: Structured Name
full name: ATP synthase F1 sector subunit beta

SIPE5DC476874342920
type: Structured Name
full name: F-ATPase subunit beta

atpD
type: Gene
locus name: THEYE_A0241

SIP2666BB5A67A57CB3
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

SIPBE048A669C61BF96
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP67F165EBFF343A30
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_1000143558
type: Chain Annotation
comment: ATP synthase subunit beta
mass: 51446
range: 18636006059291694tt1tt473

18636006059291694tt1
type: Position
type: ExactPosition
position: 1
reference: B5YI24-1

18636006059291694tt473
type: Position
type: ExactPosition
position: 473
reference: B5YI24-1

18636006059291694tt157
type: Position
type: ExactPosition
position: 157
reference: B5YI24-1

18636006059291694tt164
type: Position
type: ExactPosition
position: 164
reference: B5YI24-1

B5YI24-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 51446
value: MNVGKVVQVIGTVVDCEFEGQLPEVLNALKIEEPGDPAKGIPELHLTLEVAMHLGENRVRTIAMGSTDGLVRGMKVVDTGAPITVPVGKPVLGRIINVIGEPVDEMGPIQAQDKYPIHISAPEFTEQSPTTQQFETGVKVFDLLVPFVRGGKMGMFGGAGVGKTVIIMEMIHNIAMKHGGVSVFAGVGERTREGNDLYLEMKHSGVLPQVALVYGQMNEPPGVRARIALTALTVAEYFRDQGQDVLIFIDNIFRYTLAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITTTAKGSITSMQAIYVPADDLTDPAVAAVFAHLDGTVVLSRQIAELGIYPAVDPLDSTSRILDPRVVGDEHYQVARGVQSVLQRYKELQDIIAILGIEELSEDDKLTVARARKLQRFLSQPFHVAETFTGTPGKYVKLEDTIKGFKAILDGKYDDLPEQAFYMVGPIEEVEEKAKKMGYTRQV

http://purl.uniprot.org/uniprot/B5YI24#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI24#attribution-43A9882434E9506AAFC23F741E3F28D4
manual: true
evidence: ECO_0000255
source: MF_01347

B5YI21
type: Protein
reviewed: true
created: 2009-09-01
modified: 2023-02-22
version: 69
mnemonic: ATPD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPBD1370672D799AB1
alternative name: SIP998F9CFFBC003414
alternative name: SIP3196E599EDF744CD
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP01EE719EE499CD95
annotation: SIP5D83A56BE7892DBD
annotation: SIPB890733385602F84
annotation: SIPFBFEC14552BB2BE1
annotation: SIP88F3CE12E9E4B2B8
annotation: PRO_0000382157
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0046933
classified with: GO_0015986
sequence: MRKVRGAKAKKYAKQFLSLVNIDQVPEIVSKLETVVMLMQKEKQFRNMLTSPSFKDEERVGVIGYLCEKLGLPEETKKFLNFLSIEGVLIGLGEIVRYINALYLEAKKKVKGIVTSAVELPENIKQKIVESLKAITGRDVELQYEIDPSLIGGVRVKVGSTMYDLSIKGQLGLLRDKLIKG
proteome: Chromosome

B5YI21-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0712
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.520.20
type: Resource
database: Gene3D
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: Gene3D 1.10.520.20 match 1

MF_01416
type: Resource
database: HAMAP
comment: ATP_synth_delta_bact
signature sequence match: HAMAP MF 01416 match 1

IPR026015
type: Resource
database: InterPro
comment: ATP_synth_OSCP/delta_N_sf

IPR020781
type: Resource
database: InterPro
comment: ATPase_OSCP/d_CS

IPR000711
type: Resource
database: InterPro
comment: ATPase_OSCP/dsu

PTHR11910
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA CHAIN
signature sequence match: PANTHER PTHR11910 match 1

PTHR11910:SF22
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, CHLOROPLASTIC
signature sequence match: PANTHER PTHR11910:SF22 match 1

PF00213
type: Resource
database: Pfam
comment: OSCP
signature sequence match: Pfam PF00213 match 1

PR00125
type: Resource
database: PRINTS
comment: ATPASEDELTA

SSF47928
type: Resource
database: SUPFAM
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: SUPFAM SSF47928 match 1

TIGR01145
type: Resource
database: TIGRFAMs
comment: ATP_synt_delta
signature sequence match: TIGRFAMs TIGR01145 match 1

PS00389
type: Resource
database: PROSITE
comment: ATPASE_DELTA
signature sequence match: PROSITE PS00389 match 1

SIPBD1370672D799AB1
type: Structured Name
full name: ATP synthase subunit delta

SIP998F9CFFBC003414
type: Structured Name
full name: ATP synthase F(1) sector subunit delta

SIP3196E599EDF744CD
type: Structured Name
full name: F-type ATPase subunit delta
short name: F-ATPase subunit delta

atpH
type: Gene
locus name: THEYE_A0238

SIP01EE719EE499CD95
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP5D83A56BE7892DBD
type: Function Annotation
comment: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

SIPB890733385602F84
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP88F3CE12E9E4B2B8
type: Similarity Annotation
comment: Belongs to the ATPase delta chain family.

PRO_0000382157
type: Chain Annotation
comment: ATP synthase subunit delta
mass: 20314
range: 18636006059290926tt1tt181

18636006059290926tt1
type: Position
type: ExactPosition
position: 1
reference: MRKVRGAKAKKYAKQFLSLVNIDQVPEIVSKLETVVMLMQKEKQFRNMLTSPSFKDEERVGVIGYLCEKLGLPEETKKFLNFLSIEGVLIGLGEIVRYINALYLEAKKKVKGIVTSAVELPENIKQKIVESLKAITGRDVELQYEIDPSLIGGVRVKVGSTMYDLSIKGQLGLLRDKLIKG

18636006059290926tt181
type: Position
type: ExactPosition
position: 181
reference: MRKVRGAKAKKYAKQFLSLVNIDQVPEIVSKLETVVMLMQKEKQFRNMLTSPSFKDEERVGVIGYLCEKLGLPEETKKFLNFLSIEGVLIGLGEIVRYINALYLEAKKKVKGIVTSAVELPENIKQKIVESLKAITGRDVELQYEIDPSLIGGVRVKVGSTMYDLSIKGQLGLLRDKLIKG

MRKVRGAKAKKYAKQFLSLVNIDQVPEIVSKLETVVMLMQKEKQFRNMLTSPSFKDEERVGVIGYLCEKLGLPEETKKFLNFLSIEGVLIGLGEIVRYINALYLEAKKKVKGIVTSAVELPENIKQKIVESLKAITGRDVELQYEIDPSLIGGVRVKVGSTMYDLSIKGQLGLLRDKLIKG
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 20314

http://purl.uniprot.org/uniprot/B5YI21#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI21#attribution-B1DD1792DF5CD88DBD7981631B7C9A70
manual: true
evidence: ECO_0000255
source: MF_01416

B5YI25
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 74
mnemonic: ATPE_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP45B225C96B5B8720
alternative name: SIP1A3B8E10330D1A15
alternative name: SIPA309F3952E20E34C
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP17B3DA5B81A0E0A4
annotation: SIP3D532C4B6B50D84E
annotation: SIP43A9B7F061939753
annotation: SIPBFDE0F69E37DED8B
annotation: PRO_1000127904
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0015986
sequence: MENKLKLEVITPYGEVINEEVDEVYTTGAEGDFGVFPGHCAFMTAIRIGSLSYKKDGQMHYLFVNRGYCEVLNDRVLVLVGSAERVEEIDVERAKAALARAEERLRKAQAGETDIDLARAQAALERATIRIQLATKLIPR
proteome: Chromosome

B5YI25-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0355
type: Resource
database: eggNOG
comment: Bacteria

cd12152
type: Resource
database: CDD
comment: F1-ATPase_delta
signature sequence match: CDD cd12152 match 1

http://purl.uniprot.org/gene3d/1.20.5.440
type: Resource
database: Gene3D
comment: ATP synthase delta/epsilon subunit, C-terminal domain
signature sequence match: Gene3D 1.20.5.440 match 1

http://purl.uniprot.org/gene3d/2.60.15.10
type: Resource
database: Gene3D
comment: F0F1 ATP synthase delta/epsilon subunit, N-terminal
signature sequence match: Gene3D 2.60.15.10 match 1

MF_00530
type: Resource
database: HAMAP
comment: ATP_synth_epsil_bac
signature sequence match: HAMAP MF 00530 match 1

IPR036794
type: Resource
database: InterPro
comment: ATP_F1_dsu/esu_C_sf

IPR001469
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu

IPR020546
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu_N

IPR020547
type: Resource
database: InterPro
comment: ATP_synth_F1_esu_C

IPR036771
type: Resource
database: InterPro
comment: ATPsynth_dsu/esu_N

PTHR13822
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA/EPSILON CHAIN
signature sequence match: PANTHER PTHR13822 match 1

PTHR13822:SF7
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR13822:SF7 match 1

PF00401
type: Resource
database: Pfam
comment: ATP-synt_DE
signature sequence match: Pfam PF00401 match 1

PF02823
type: Resource
database: Pfam
comment: ATP-synt_DE_N
signature sequence match: Pfam PF02823 match 1

SSF46604
type: Resource
database: SUPFAM
comment: Epsilon subunit of F1F0-ATP synthase C-terminal domain
signature sequence match: SUPFAM SSF46604 match 1

SSF51344
type: Resource
database: SUPFAM
comment: Epsilon subunit of F1F0-ATP synthase N-terminal domain
signature sequence match: SUPFAM SSF51344 match 1

TIGR01216
type: Resource
database: TIGRFAMs
comment: ATP_synt_epsi
signature sequence match: TIGRFAMs TIGR01216 match 1

SIP45B225C96B5B8720
type: Structured Name
full name: ATP synthase epsilon chain

SIP1A3B8E10330D1A15
type: Structured Name
full name: ATP synthase F1 sector epsilon subunit

SIPA309F3952E20E34C
type: Structured Name
full name: F-ATPase epsilon subunit

atpC
type: Gene
locus name: THEYE_A0242

SIP17B3DA5B81A0E0A4
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane.

SIP3D532C4B6B50D84E
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPBFDE0F69E37DED8B
type: Similarity Annotation
comment: Belongs to the ATPase epsilon chain family.

PRO_1000127904
type: Chain Annotation
comment: ATP synthase epsilon chain
mass: 15627
range: 18636006059291950tt1tt140

18636006059291950tt1
type: Position
type: ExactPosition
position: 1
reference: MENKLKLEVITPYGEVINEEVDEVYTTGAEGDFGVFPGHCAFMTAIRIGSLSYKKDGQMHYLFVNRGYCEVLNDRVLVLVGSAERVEEIDVERAKAALARAEERLRKAQAGETDIDLARAQAALERATIRIQLATKLIPR

18636006059291950tt140
type: Position
type: ExactPosition
position: 140
reference: MENKLKLEVITPYGEVINEEVDEVYTTGAEGDFGVFPGHCAFMTAIRIGSLSYKKDGQMHYLFVNRGYCEVLNDRVLVLVGSAERVEEIDVERAKAALARAEERLRKAQAGETDIDLARAQAALERATIRIQLATKLIPR

MENKLKLEVITPYGEVINEEVDEVYTTGAEGDFGVFPGHCAFMTAIRIGSLSYKKDGQMHYLFVNRGYCEVLNDRVLVLVGSAERVEEIDVERAKAALARAEERLRKAQAGETDIDLARAQAALERATIRIQLATKLIPR
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 15627

http://purl.uniprot.org/uniprot/B5YI25#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI25#attribution-010E2FDA382798F3C5F7883FA248BBDD
manual: true
evidence: ECO_0000255
source: MF_00530

B5YI20
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 68
mnemonic: ATPF_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP9908B01B6DDF809F
alternative name: SIP2DA520AFF070A505
alternative name: SIP21033C35161E7941
alternative name: SIPAF55909EB1107504
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP18BD9F8455757505
annotation: SIP6F0114AA2F191FD5
annotation: SIP913516E561E7CB65
annotation: SIP3B8B111A430E4BE9
annotation: SIP29659DFD6C3372A6
annotation: PRO_0000368839
annotation: SIPB93F66556458B12A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN
proteome: Chromosome

B5YI20-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0711
type: Resource
database: eggNOG
comment: Bacteria

cd06503
type: Resource
database: CDD
comment: ATP-synt_Fo_b
signature sequence match: CDD cd06503 match 1

MF_01398
type: Resource
database: HAMAP
comment: ATP_synth_b_bprime
signature sequence match: HAMAP MF 01398 match 1

IPR002146
type: Resource
database: InterPro
comment: ATP_synth_b/b'su_bac/chlpt

IPR005864
type: Resource
database: InterPro
comment: ATP_synth_F0_bsu_bac

PTHR33445:SF1
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B
signature sequence match: PANTHER PTHR33445:SF1 match 1

PTHR33445
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B', CHLOROPLASTIC
signature sequence match: PANTHER PTHR33445 match 1

PF00430
type: Resource
database: Pfam
comment: ATP-synt_B
signature sequence match: Pfam PF00430 match 1

TIGR01144
type: Resource
database: TIGRFAMs
comment: ATP_synt_b
signature sequence match: TIGRFAMs TIGR01144 match 1

SIP9908B01B6DDF809F
type: Structured Name
full name: ATP synthase subunit b

SIP2DA520AFF070A505
type: Structured Name
full name: ATP synthase F(0) sector subunit b

SIP21033C35161E7941
type: Structured Name
full name: ATPase subunit I

SIPAF55909EB1107504
type: Structured Name
full name: F-type ATPase subunit b
short name: F-ATPase subunit b

atpF
type: Gene
locus name: THEYE_A0237

SIP18BD9F8455757505
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP6F0114AA2F191FD5
type: Function Annotation
comment: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).

SIP913516E561E7CB65
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP29659DFD6C3372A6
type: Similarity Annotation
comment: Belongs to the ATPase B chain family.

PRO_0000368839
type: Chain Annotation
comment: ATP synthase subunit b
mass: 21583
range: 18636006059290670tt1tt188

18636006059290670tt1
type: Position
type: ExactPosition
position: 1
reference: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN

18636006059290670tt188
type: Position
type: ExactPosition
position: 188
reference: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN

SIPB93F66556458B12A
type: Transmembrane Annotation
comment: Helical
range: 18636006059290670tt5tt25

18636006059290670tt5
type: Position
type: ExactPosition
position: 5
reference: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN

18636006059290670tt25
type: Position
type: ExactPosition
position: 25
reference: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN

MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 21583

http://purl.uniprot.org/uniprot/B5YI20#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI20#attribution-F532F36C147A4DB2E74653A5DA543EB9
manual: true
evidence: ECO_0000255
source: MF_01398

B5YGC8
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 67
mnemonic: ATPL_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP5FF7173628D234E4
alternative name: SIPB0BFD942ED335F81
alternative name: SIP36C9FA1BB6433AC0
alternative name: SIP47A478988503071F
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPE71A25B1DD706942
annotation: SIPA9A30E3D574591BF
annotation: SIPE91707DBDBDA8F0C
annotation: SIP87ACD5905077494B
annotation: SIPDC68FBC312AC8CD2
annotation: PRO_1000184521
annotation: SIPB735E5FA3ECBF35D
annotation: SIP438B21EB8BD3EB36
annotation: SIP94D5BB68AA602136
annotation: SIP521AA23A3E558EB3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/446
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0008289
classified with: GO_0046933
classified with: GO_0015986
sequence: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK
proteome: Chromosome

B5YGC8-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0636
type: Resource
database: eggNOG
comment: Bacteria

cd18121
type: Resource
database: CDD
comment: ATP-synt_Fo_c
signature sequence match: CDD cd18121 match 1

http://purl.uniprot.org/gene3d/1.20.20.10
type: Resource
database: Gene3D
comment: F1F0 ATP synthase subunit C
signature sequence match: Gene3D 1.20.20.10 match 1

MF_01396
type: Resource
database: HAMAP
comment: ATP_synth_c_bact
signature sequence match: HAMAP MF 01396 match 1

IPR000454
type: Resource
database: InterPro
comment: ATP_synth_F0_csu

IPR020537
type: Resource
database: InterPro
comment: ATP_synth_F0_csu_DDCD_BS

IPR038662
type: Resource
database: InterPro
comment: ATP_synth_F0_csu_sf

IPR002379
type: Resource
database: InterPro
comment: ATPase_proteolipid_c-like_dom

IPR035921
type: Resource
database: InterPro
comment: F/V-ATP_Csub_sf

PF00137
type: Resource
database: Pfam
comment: ATP-synt_C
signature sequence match: Pfam PF00137 match 1

PR00124
type: Resource
database: PRINTS
comment: ATPASEC

SSF81333
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit C
signature sequence match: SUPFAM SSF81333 match 1

PS00605
type: Resource
database: PROSITE
comment: ATPASE_C
signature sequence match: PROSITE PS00605 match 1

SIP5FF7173628D234E4
type: Structured Name
full name: ATP synthase subunit c

SIPB0BFD942ED335F81
type: Structured Name
full name: ATP synthase F(0) sector subunit c

SIP36C9FA1BB6433AC0
type: Structured Name
full name: F-type ATPase subunit c
short name: F-ATPase subunit c

SIP47A478988503071F
type: Structured Name
full name: Lipid-binding protein

atpE
type: Gene
locus name: THEYE_A1529

SIPE71A25B1DD706942
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIPA9A30E3D574591BF
type: Function Annotation
comment: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

SIPE91707DBDBDA8F0C
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPDC68FBC312AC8CD2
type: Similarity Annotation
comment: Belongs to the ATPase C chain family.

PRO_1000184521
type: Chain Annotation
comment: ATP synthase subunit c
mass: 11303
range: 18636006026852398tt1tt110

18636006026852398tt1
type: Position
type: ExactPosition
position: 1
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

18636006026852398tt110
type: Position
type: ExactPosition
position: 110
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

SIPB735E5FA3ECBF35D
type: Transmembrane Annotation
comment: Helical
range: 18636006026852398tt4tt24

18636006026852398tt4
type: Position
type: ExactPosition
position: 4
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

18636006026852398tt24
type: Position
type: ExactPosition
position: 24
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

SIP438B21EB8BD3EB36
type: Transmembrane Annotation
comment: Helical
range: 18636006026852398tt37tt57

18636006026852398tt37
type: Position
type: ExactPosition
position: 37
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

18636006026852398tt57
type: Position
type: ExactPosition
position: 57
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

SIP94D5BB68AA602136
type: Transmembrane Annotation
comment: Helical
range: 18636006026852398tt81tt101

18636006026852398tt81
type: Position
type: ExactPosition
position: 81
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

18636006026852398tt101
type: Position
type: ExactPosition
position: 101
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

SIP521AA23A3E558EB3
type: Site Annotation
comment: Reversibly protonated during proton transport
range: 18636006026852398tt89tt89

18636006026852398tt89
type: Position
type: ExactPosition
position: 89
reference: MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK

MRKFFVILMVALVVVLTASAVFAADSDPAKLNYYGYATAGALIGLGAAAGGGGAGMGQGLRGILEGSARNPGVTGKLMTLFIVGLALIESLVIYVLVFVLITFYANPFVK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 11303

http://purl.uniprot.org/uniprot/B5YGC8#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YGC8#attribution-A30093FC3652A8EBF93668C13F9E1E0F
manual: true
evidence: ECO_0000255
source: MF_01396

B5YK85
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 77
mnemonic: BIOB_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPBB15AFB22594DDF3
enzyme: http://purl.uniprot.org/enzyme/2.8.1.6
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP07F38EBBD3AE4C6B
annotation: SIP8255FA55303503F7
annotation: SIP6B30B04F2528D2EA
annotation: SIP634C24A38CB1ACE7
annotation: SIPB50B0DC15A444BDB
annotation: SIP72BC35D2DE663058
annotation: SIPA9007F24E098E754
annotation: PRO_0000381688
annotation: SIPA0394740BDC22214
annotation: SIP97D891CDECCDC2E1
annotation: SIP78521C6135FF8371
annotation: SIP697484D5CBDDA821
annotation: SIP6FF5994DBCCE39E3
annotation: SIPFBDB6F0F362DE856
annotation: SIP03F8EF7C5824EC28
annotation: SIP1D5D345EA7F76CB4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/949
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0051537
classified with: GO_0051539
classified with: GO_0004076
classified with: GO_0005506
classified with: GO_0009102
sequence: B5YK85-1
proteome: Chromosome

B5YK85-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0502
type: Resource
database: eggNOG
comment: Bacteria

cd01335
type: Resource
database: CDD
comment: Radical_SAM
signature sequence match: CDD cd01335 match 1

MF_01694
type: Resource
database: HAMAP
comment: BioB
signature sequence match: HAMAP MF 01694 match 1

IPR010722
type: Resource
database: InterPro
comment: BATS_dom

IPR002684
type: Resource
database: InterPro
comment: Biotin_synth/BioAB

IPR024177
type: Resource
database: InterPro
comment: Biotin_synthase

IPR006638
type: Resource
database: InterPro
comment: Elp3/MiaA/NifB-like_rSAM

IPR007197
type: Resource
database: InterPro
comment: rSAM

PTHR22976
type: Resource
database: PANTHER
comment: BIOTIN SYNTHASE
signature sequence match: PANTHER PTHR22976 match 1

PTHR22976:SF2
type: Resource
database: PANTHER
comment: BIOTIN SYNTHASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR22976:SF2 match 1

PF06968
type: Resource
database: Pfam
comment: BATS
signature sequence match: Pfam PF06968 match 1

PF04055
type: Resource
database: Pfam
comment: Radical_SAM
signature sequence match: Pfam PF04055 match 1

PIRSF001619
type: Resource
database: PIRSF
comment: Biotin_synth
signature sequence match: PIRSF PIRSF001619 match 1

SFLDG01278
type: Resource
database: SFLD
comment: biotin_synthase_like
signature sequence match: SFLD SFLDG01278 match 1

SFLDS00029
type: Resource
database: SFLD
comment: Radical_SAM
signature sequence match: SFLD SFLDS00029 match 1

SM00876
type: Resource
database: SMART
comment: BATS
signature sequence match: SMART SM00876 match 1

SM00729
type: Resource
database: SMART
comment: Elp3
signature sequence match: SMART SM00729 match 1

SSF102114
type: Resource
database: SUPFAM
comment: Radical SAM enzymes
signature sequence match: SUPFAM SSF102114 match 1

TIGR00433
type: Resource
database: TIGRFAMs
comment: bioB
signature sequence match: TIGRFAMs TIGR00433 match 1

PS51918
type: Resource
database: PROSITE
comment: RADICAL_SAM
signature sequence match: PROSITE PS51918 match 1

SIPBB15AFB22594DDF3
type: Structured Name
full name: Biotin synthase
ec name: 2.8.1.6

bioB
type: Gene
locus name: THEYE_A0809

SIP07F38EBBD3AE4C6B
type: Function Annotation
comment: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.

SIP6B30B04F2528D2EA
type: Cofactor Annotation
comment: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
cofactor: CHEBI_49883

SIP634C24A38CB1ACE7
type: Cofactor Annotation
comment: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
cofactor: CHEBI_190135

SIP72BC35D2DE663058
type: Subunit Annotation
comment: Homodimer.

SIPA9007F24E098E754
type: Similarity Annotation
comment: Belongs to the radical SAM superfamily. Biotin synthase family.

PRO_0000381688
type: Chain Annotation
comment: Biotin synthase
mass: 35460
range: 18636006093239598tt1tt316

18636006093239598tt1
type: Position
type: ExactPosition
position: 1
reference: B5YK85-1

18636006093239598tt316
type: Position
type: ExactPosition
position: 316
reference: B5YK85-1

SIPA0394740BDC22214
type: Domain Extent Annotation
comment: Radical SAM core
range: 18636006093239598tt38tt266

18636006093239598tt38
type: Position
type: ExactPosition
position: 38
reference: B5YK85-1

18636006093239598tt266
type: Position
type: ExactPosition
position: 266
reference: B5YK85-1

18636006093239598tt56
type: Position
type: ExactPosition
position: 56
reference: B5YK85-1

18636006093239598tt60
type: Position
type: ExactPosition
position: 60
reference: B5YK85-1

18636006093239598tt63
type: Position
type: ExactPosition
position: 63
reference: B5YK85-1

18636006093239598tt100
type: Position
type: ExactPosition
position: 100
reference: B5YK85-1

18636006093239598tt131
type: Position
type: ExactPosition
position: 131
reference: B5YK85-1

18636006093239598tt191
type: Position
type: ExactPosition
position: 191
reference: B5YK85-1

18636006093239598tt261
type: Position
type: ExactPosition
position: 261
reference: B5YK85-1

SIP0EB8875058CDA956
subclass of: CHEBI_49883
comment: 4Fe-4S-S-AdoMet

B5YK85-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 35460
value: MKPEIQSSLEYYSDLIEHMDDSHIYSLIFQANSIREKYKGKKIELCAIVNAKSGLCSEDCAFCAQSSRYKTNSPVYSLLEKDEIVKKALEAKKYGVKRFSIVISGKKPSKKELEKIGNSIEAIKKIGIYPCASLGLLEYDEICYLRDKGLERLHCNIETSERFFSNICTTHKFSDKVKTLENANKTGLSICSGGVFGIGESWDDRKEMAEFLKNLNVDSIPINFLTPIKGTPLESKKPLNPMEALRIIILFRLILPDKDIRVCGGRPLLGEFASWIFIAGANALMTGNYLTTTGRHYSDDIKFIEAHGLEVDSVVS

http://purl.uniprot.org/uniprot/B5YK85#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YK85#attribution-55428B9244A0EC48C2387090F66C8227
manual: true
evidence: ECO_0000255
source: MF_01694

http://purl.uniprot.org/uniprot/B5YK85#attribution-3F4EA4141FE4507DF0695D0A72C2893B
manual: true
evidence: ECO_0000255
source: PRU01266

B5YHS9
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 77
mnemonic: BIOD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP7279B3F6E4E89E2E
alternative name: SIP861E91FCCA1316D2
alternative name: SIPF9BBE94D19CA5B50
enzyme: http://purl.uniprot.org/enzyme/6.3.3.3
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP9EDB875D80CD50D6
annotation: SIP26E734D251FC07F9
annotation: SIP29E4F590D0EF93CB
annotation: SIP51ED977F17FFBFEC
annotation: SIPBC01A01118D8F843
annotation: SIPFC75268498580D63
annotation: SIPEB4935DFC87D4FE8
annotation: PRO_1000119884
annotation: SIP73905AFAEA14AD36
annotation: SIP1600013904E8D5DA
annotation: SIPDC4D46FFE53B959E
annotation: SIPA2711489AEFDBC32
annotation: SIP491138E7DD0FEAA8
annotation: SIPAD653981CD32E6BB
annotation: SIP9C315C29E7314BD3
annotation: SIPB4F0C532EDAB3FBB
annotation: SIP3CEFFD17EC977CA2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0005524
classified with: GO_0004141
classified with: GO_0000287
classified with: GO_0009102
sequence: B5YHS9-1
proteome: Chromosome

B5YHS9-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0132
type: Resource
database: eggNOG
comment: Bacteria

cd03109
type: Resource
database: CDD
comment: DTBS
signature sequence match: CDD cd03109 match 1

MF_00336
type: Resource
database: HAMAP
comment: BioD
signature sequence match: HAMAP MF 00336 match 1

IPR004472
type: Resource
database: InterPro
comment: DTB_synth_BioD

PTHR43210
type: Resource
database: PANTHER
comment: DETHIOBIOTIN SYNTHETASE
signature sequence match: PANTHER PTHR43210 match 1

PTHR43210:SF2
type: Resource
database: PANTHER
comment: DETHIOBIOTIN SYNTHETASE
signature sequence match: PANTHER PTHR43210:SF2 match 1

PF13500
type: Resource
database: Pfam
comment: AAA_26
signature sequence match: Pfam PF13500 match 1

PIRSF006755
type: Resource
database: PIRSF
comment: DTB_synth
signature sequence match: PIRSF PIRSF006755 match 1

TIGR00347
type: Resource
database: TIGRFAMs
comment: bioD
signature sequence match: TIGRFAMs TIGR00347 match 1

SIP7279B3F6E4E89E2E
type: Structured Name
full name: ATP-dependent dethiobiotin synthetase BioD
ec name: 6.3.3.3

SIP861E91FCCA1316D2
type: Structured Name
full name: DTB synthetase
short name: DTBS

SIPF9BBE94D19CA5B50
type: Structured Name
full name: Dethiobiotin synthase

bioD
type: Gene
locus name: THEYE_A1875

SIP9EDB875D80CD50D6
type: Function Annotation
comment: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.

SIPBC01A01118D8F843
type: Subunit Annotation
comment: Homodimer.

SIPEB4935DFC87D4FE8
type: Similarity Annotation
comment: Belongs to the dethiobiotin synthetase family.

PRO_1000119884
type: Chain Annotation
comment: ATP-dependent dethiobiotin synthetase BioD
mass: 26657
range: 18636006044678446tt1tt240

18636006044678446tt1
type: Position
type: ExactPosition
position: 1
reference: B5YHS9-1

18636006044678446tt240
type: Position
type: ExactPosition
position: 240
reference: B5YHS9-1

18636006044678446tt38
type: Position
type: ExactPosition
position: 38
reference: B5YHS9-1

18636006044678446tt13
type: Position
type: ExactPosition
position: 13
reference: B5YHS9-1

18636006044678446tt18
type: Position
type: ExactPosition
position: 18
reference: B5YHS9-1

18636006044678446tt17
type: Position
type: ExactPosition
position: 17
reference: B5YHS9-1

18636006044678446tt42
type: Position
type: ExactPosition
position: 42
reference: B5YHS9-1

18636006044678446tt55
type: Position
type: ExactPosition
position: 55
reference: B5YHS9-1

18636006044678446tt116
type: Position
type: ExactPosition
position: 116
reference: B5YHS9-1

18636006044678446tt119
type: Position
type: ExactPosition
position: 119
reference: B5YHS9-1

18636006044678446tt214
type: Position
type: ExactPosition
position: 214
reference: B5YHS9-1

18636006044678446tt216
type: Position
type: ExactPosition
position: 216
reference: B5YHS9-1

substrate

B5YHS9-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 26657
value: MKAGYFITGTDTGVGKTIVTSAILRSFIKKGLKVGAMKVIETGCLNKDGILLPSDGMLLRDMAEMNDSLDLITPIKLENPLSPLVASRIEEIEVDIERIFRAFETLQKKYDYLLVEGVGGLMVPLNKEEKKKSMFYFVRDLIKDMGLPVILVTRPTLGTINHTLLTLEALKNKKISVKGYIINFSEPAKNDIAEKTNPQVLKELVDVPCLGILPYLTELNKDKIGETAIKNFDIEALISL

http://purl.uniprot.org/uniprot/B5YHS9#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YHS9#attribution-9C497BC303592833BAC5F2A7F6EC53D8
manual: true
evidence: ECO_0000255
source: MF_00336

B5YFU5
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 78
mnemonic: BIOF_THEYD
old mnemonic: BIKB_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPEB2BD114E25B4DDD
alternative name: SIP15497E4716633857
alternative name: SIPD3A475FA85257690
enzyme: http://purl.uniprot.org/enzyme/2.3.1.47
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP49C4D6F35C848B6A
annotation: SIPF3CE9504BFBBE527
annotation: SIPB7E8EDEE1734ACFB
annotation: SIP3B010ED34E4AF9CE
annotation: SIPF83A3E636E40CE8F
annotation: SIPA1E4F4BCD8BAD7CC
annotation: PRO_0000381126
annotation: SIPD67E8F454579B8FD
annotation: SIP1FB58B5329FDB0F0
annotation: SIP04BEB941EFA368D0
annotation: SIPD52CD16F3E32C731
annotation: SIP58CDDC02F2A62DDC
annotation: SIP14CA00DF240CBF28
annotation: SIP7D7BB5A3BFC56009
annotation: SIP05F7D2BA250FFA00
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0008710
classified with: GO_0030170
classified with: GO_0009102
sequence: B5YFU5-1
proteome: Chromosome

B5YFU5-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0156
type: Resource
database: eggNOG
comment: Bacteria

cd06454
type: Resource
database: CDD
comment: KBL_like
signature sequence match: CDD cd06454 match 1

http://purl.uniprot.org/gene3d/3.90.1150.10
type: Resource
database: Gene3D
comment: Aspartate Aminotransferase, domain 1
signature sequence match: Gene3D 3.90.1150.10 match 1

http://purl.uniprot.org/gene3d/3.40.640.10
type: Resource
database: Gene3D
comment: Type I PLP-dependent aspartate aminotransferase-like (Major domain)
signature sequence match: Gene3D 3.40.640.10 match 1

IPR001917
type: Resource
database: InterPro
comment: Aminotrans_II_pyridoxalP_BS

IPR004839
type: Resource
database: InterPro
comment: Aminotransferase_I/II

IPR004723
type: Resource
database: InterPro
comment: AONS_Archaea/Proteobacteria

IPR015424
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase

IPR015421
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_major

IPR015422
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_small

PTHR13693:SF77
type: Resource
database: PANTHER
comment: 8-AMINO-7-OXONONANOATE SYNTHASE
signature sequence match: PANTHER PTHR13693:SF77 match 1

PTHR13693
type: Resource
database: PANTHER
comment: CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE
signature sequence match: PANTHER PTHR13693 match 1

PF00155
type: Resource
database: Pfam
comment: Aminotran_1_2
signature sequence match: Pfam PF00155 match 1

SSF53383
type: Resource
database: SUPFAM
comment: PLP-dependent transferases
signature sequence match: SUPFAM SSF53383 match 1

TIGR00858
type: Resource
database: TIGRFAMs
comment: bioF
signature sequence match: TIGRFAMs TIGR00858 match 1

PS00599
type: Resource
database: PROSITE
comment: AA_TRANSFER_CLASS_2
signature sequence match: PROSITE PS00599 match 1

SIPEB2BD114E25B4DDD
type: Structured Name
full name: Putative 8-amino-7-oxononanoate synthase
short name: AONS
ec name: 2.3.1.47

SIP15497E4716633857
type: Structured Name
full name: 7-keto-8-amino-pelargonic acid synthase
short name: 7-KAP synthase

SIPD3A475FA85257690
type: Structured Name
full name: 8-amino-7-ketopelargonate synthase

bioF
type: Gene
locus name: THEYE_A1333

SIP49C4D6F35C848B6A
type: Function Annotation
comment: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.

SIPF83A3E636E40CE8F
type: Subunit Annotation
comment: Homodimer.

SIPA1E4F4BCD8BAD7CC
type: Similarity Annotation
comment: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

PRO_0000381126
type: Chain Annotation
comment: Putative 8-amino-7-oxononanoate synthase
mass: 42922
range: 18636006011254062tt1tt388

18636006011254062tt1
type: Position
type: ExactPosition
position: 1
reference: B5YFU5-1

18636006011254062tt388
type: Position
type: ExactPosition
position: 388
reference: B5YFU5-1

18636006011254062tt23
type: Position
type: ExactPosition
position: 23
reference: B5YFU5-1

18636006011254062tt110
type: Position
type: ExactPosition
position: 110
reference: B5YFU5-1

18636006011254062tt111
type: Position
type: ExactPosition
position: 111
reference: B5YFU5-1

18636006011254062tt135
type: Position
type: ExactPosition
position: 135
reference: B5YFU5-1

18636006011254062tt182
type: Position
type: ExactPosition
position: 182
reference: B5YFU5-1

18636006011254062tt207
type: Position
type: ExactPosition
position: 207
reference: B5YFU5-1

18636006011254062tt210
type: Position
type: ExactPosition
position: 210
reference: B5YFU5-1

18636006011254062tt238
type: Position
type: ExactPosition
position: 238
reference: B5YFU5-1

18636006011254062tt241
type: Position
type: ExactPosition
position: 241
reference: B5YFU5-1

18636006011254062tt355
type: Position
type: ExactPosition
position: 355
reference: B5YFU5-1

SIP05F7D2BA250FFA00
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18636006011254062tt241tt241

substrate

B5YFU5-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 42922
value: MSEKFFEIFEKKLEKLKEQNLYRSVKDMESRHGMEITIQGKKYINFASNDYLGLSQHPLVKEAGIDAIKTFGAGGGASRLLSGGTILHRKLEELLSEFKNTESCLILNSGYTANTSLIPALAGENDIIFSDELNHASIIDGCRLSRAEKIIYKHADIEDLKKLIRNISCKGKKVIITDTVFSMDGDIAPIRELYELCKAEGALLYIDDAHGTGVLGNGYGILKHLGLQTEAFVIQMGTLSKAIGVFGAFVCGDSSIIDWFINSARGFIFSTSLPPSTVASAYASLKIIMEDKELIKRLWQNIEKVMEIIKNLELKTTKTQTPIIPILFENIEQAIKASRILYDSGIYAPVIRPPTVKTPRIRITITAGHSDNDIEKLSGALTLLNSIF

http://purl.uniprot.org/uniprot/B5YFU5#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/B5YFU5#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B5YK86
type: Protein
reviewed: true
created: 2011-07-27
modified: 2023-05-03
version: 59
mnemonic: BIOW_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPB9BF516D10FEEFD1
alternative name: SIP3CD88B6C40BF5315
enzyme: http://purl.uniprot.org/enzyme/6.2.1.14
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPECE97F4AE166B5DA
annotation: SIPA49D1D400DACDF7D
annotation: SIP88DA1D09D9BC19ED
annotation: SIPC2A24E33039A7666
annotation: SIP72607D039701B188
annotation: SIP3EF468F68CF1519C
annotation: PRO_0000412092
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0042410
classified with: GO_0005524
classified with: GO_0000287
classified with: GO_0009102
sequence: B5YK86-1
proteome: Chromosome

B5YK86-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1424
type: Resource
database: eggNOG
comment: Bacteria

MF_00668
type: Resource
database: HAMAP
comment: BioW
signature sequence match: HAMAP MF 00668 match 1

IPR005499
type: Resource
database: InterPro
comment: BioW

PF03744
type: Resource
database: Pfam
comment: BioW
signature sequence match: Pfam PF03744 match 1

TIGR01204
type: Resource
database: TIGRFAMs
comment: bioW
signature sequence match: TIGRFAMs TIGR01204 match 1

SIPB9BF516D10FEEFD1
type: Structured Name
full name: 6-carboxyhexanoate--CoA ligase
ec name: 6.2.1.14

SIP3CD88B6C40BF5315
type: Structured Name
full name: Pimeloyl-CoA synthase

bioW
type: Gene
locus name: THEYE_A0810

SIPECE97F4AE166B5DA
type: Function Annotation
comment: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.

SIP72607D039701B188
type: Subunit Annotation
comment: Homodimer.

SIP3EF468F68CF1519C
type: Similarity Annotation
comment: Belongs to the BioW family.

PRO_0000412092
type: Chain Annotation
comment: 6-carboxyhexanoate--CoA ligase
mass: 27958
range: 18636006093239854tt1tt245

18636006093239854tt1
type: Position
type: ExactPosition
position: 1
reference: B5YK86-1

18636006093239854tt245
type: Position
type: ExactPosition
position: 245
reference: B5YK86-1

B5YK86-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 27958
value: MWSVRMRASKKENNIEKHISGAEGIYDYSQIERVLKQLFKRAFEHSKGKPDKVVITVERINEEIQTVSALPVNTFFTNSPEEAFCLISEKLSSIGISDKALFSAFEVIKKYPMRGATLIDSITGERLERDKTRGIRVSRIHMDKRKRMKLIRQIKNLSTQPQRVIEAITIASKVASYPEVVAELCISDNPDYTIGYIASRDLGYLRITNIKNKGETIGGRAFFVKTPCDIEKLTNYLERKPVLVI

http://purl.uniprot.org/uniprot/B5YK86#attribution-BEA94FB9FBBBB8779C7B30593C4B9D94
manual: true
evidence: ECO_0000255
source: MF_00668

B5YJS2
type: Protein
reviewed: true
created: 2012-05-16
modified: 2023-02-22
version: 61
mnemonic: CAS1A_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP55639AA3CDCE7112
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP0D6FF817764EA7EE
annotation: SIP6FF65EF31D0A6DBE
annotation: SIP1C389C0CF87557E8
annotation: SIP062838B08C94579B
annotation: PRO_0000417086
annotation: SIP8B09D8C5947D076F
annotation: SIP811E02E5B212D010
annotation: SIP72F07FF1330F77C5
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003677
classified with: GO_0004519
classified with: GO_0046872
classified with: GO_0051607
classified with: GO_0043571
sequence: B5YJS2-1
proteome: Chromosome

B5YJS2-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1518
type: Resource
database: eggNOG
comment: Bacteria

cd09634
type: Resource
database: CDD
comment: Cas1_I-II-III
signature sequence match: CDD cd09634 match 1

http://purl.uniprot.org/gene3d/1.20.120.920
type: Resource
database: Gene3D
comment: CRISPR-associated endonuclease Cas1, C-terminal domain
signature sequence match: Gene3D 1.20.120.920 match 1

http://purl.uniprot.org/gene3d/3.100.10.20
type: Resource
database: Gene3D
comment: CRISPR-associated endonuclease Cas1, N-terminal domain
signature sequence match: Gene3D 3.100.10.20 match 1

MF_01470
type: Resource
database: HAMAP
comment: Cas1
signature sequence match: HAMAP MF 01470 match 1

IPR002729
type: Resource
database: InterPro
comment: CRISPR-assoc_Cas1

IPR042206
type: Resource
database: InterPro
comment: CRISPR-assoc_Cas1_C

IPR042211
type: Resource
database: InterPro
comment: CRISPR-assoc_Cas1_N

PTHR34353
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1
signature sequence match: PANTHER PTHR34353 match 1

PTHR34353:SF2
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1
signature sequence match: PANTHER PTHR34353:SF2 match 1

PF01867
type: Resource
database: Pfam
comment: Cas_Cas1
signature sequence match: Pfam PF01867 match 1

TIGR00287
type: Resource
database: TIGRFAMs
comment: cas1
signature sequence match: TIGRFAMs TIGR00287 match 1

SIP55639AA3CDCE7112
type: Structured Name
full name: CRISPR-associated endonuclease Cas1 1
ec name: 3.1.-.-

cas1-1
type: Gene
locus name: THEYE_A0644

SIP0D6FF817764EA7EE
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIP1C389C0CF87557E8
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas2 homodimer.

SIP062838B08C94579B
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endonuclease Cas1 family.

PRO_0000417086
type: Chain Annotation
comment: CRISPR-associated endonuclease Cas1 1
mass: 36548
range: 18636006078231086tt1tt318

18636006078231086tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJS2-1

18636006078231086tt318
type: Position
type: ExactPosition
position: 318
reference: B5YJS2-1

18636006078231086tt160
type: Position
type: ExactPosition
position: 160
reference: B5YJS2-1

18636006078231086tt225
type: Position
type: ExactPosition
position: 225
reference: B5YJS2-1

18636006078231086tt240
type: Position
type: ExactPosition
position: 240
reference: B5YJS2-1

B5YJS2-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 36548
value: MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHGITVLFLTGKLKYSGILNGPLHNNGLLRVKQYQKSLSGFSLKFAKELIKRKIVSQRDFLSEIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNSLKFVRRIKRPPKDPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRESLACDLVELFRVNVDRFVYELFKAKHLGNRDFMKDEESGGVYLKKTGRKKFYPLYEQWVQQQRTIWRGEVQGFARRILEEKDIISG

http://purl.uniprot.org/uniprot/B5YJS2#attribution-1E5D5B72DE6977837297A311880B82C9
manual: true
evidence: ECO_0000255
source: MF_01470

B5YL10
type: Protein
reviewed: true
created: 2012-05-16
modified: 2023-05-03
version: 63
mnemonic: CAS1B_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP521B102DB3D88B0C
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP848282B2D397C55C
annotation: SIP0A9684CCA8FD4D7E
annotation: SIPDF197A3FCCAE3615
annotation: SIP1289BA4ED5A92080
annotation: PRO_0000417087
annotation: SIP2233EF6A52E71DEE
annotation: SIP58F84931DCF4CD55
annotation: SIPCB1DEE55B805333F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003677
classified with: GO_0004520
classified with: GO_0046872
classified with: GO_0051607
classified with: GO_0043571
sequence: B5YL10-1
proteome: Chromosome

B5YL10-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

cd09722
type: Resource
database: CDD
comment: Cas1_I-B
signature sequence match: CDD cd09722 match 1

IPR019858
type: Resource
database: InterPro
comment: CRISPR-assoc_Cas1_HMARI/TNEAP

PTHR43219
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDONUCLEASE CAS1
signature sequence match: PANTHER PTHR43219 match 1

PTHR43219:SF1
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDONUCLEASE CAS1
signature sequence match: PANTHER PTHR43219:SF1 match 1

TIGR03641
type: Resource
database: TIGRFAMs
comment: cas1_HMARI
signature sequence match: TIGRFAMs TIGR03641 match 1

SIP521B102DB3D88B0C
type: Structured Name
full name: CRISPR-associated endonuclease Cas1 2
ec name: 3.1.-.-

cas1-2
type: Gene
alternative label: cas1_1
locus name: THEYE_A1101

SIP848282B2D397C55C
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIPDF197A3FCCAE3615
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas2 homodimer.

SIP1289BA4ED5A92080
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endonuclease Cas1 family.

PRO_0000417087
type: Chain Annotation
comment: CRISPR-associated endonuclease Cas1 2
mass: 39190
range: 18636006109556782tt1tt330

18636006109556782tt1
type: Position
type: ExactPosition
position: 1
reference: B5YL10-1

18636006109556782tt330
type: Position
type: ExactPosition
position: 330
reference: B5YL10-1

18636006109556782tt156
type: Position
type: ExactPosition
position: 156
reference: B5YL10-1

18636006109556782tt222
type: Position
type: ExactPosition
position: 222
reference: B5YL10-1

18636006109556782tt237
type: Position
type: ExactPosition
position: 237
reference: B5YL10-1

B5YL10-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 39190
value: MKKSLYIISDGELKRKDNTLYFETSEERKYIPVENTREILIFGEVSMNKRLLEFLTESEIIIHFFNYYGYYIGSFYPREHLNSGYMILKQAEHYLDTGKRLNLAEKFVSGAIENIKKVLIYYHNRGKELSEIISKIQEIATNIPDCSTTDELMAIEGNIRDYYYQSFDIILDNEHFIFETRTKRPPKNRINALISFANSLVYTTCLSEIYQTHLDPRIGYLHATNFRRFTLNLDVAEIFKPIIADRAIFSIVNKRIVKPQHFEKKLDGIVLNDKGKQILLQEMDERLRSTIQHKKLGRHVSYRQLIRLELYKIQKHLMEEEEYKPFVTGW

http://purl.uniprot.org/uniprot/B5YL10#attribution-1E5D5B72DE6977837297A311880B82C9
manual: true
evidence: ECO_0000255
source: MF_01470

B5YIU9
type: Protein
reviewed: true
created: 2012-05-16
modified: 2023-05-03
version: 64
mnemonic: CAS1C_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP204C55B0F13AD9DB
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPEFADA6A22BAA4FB4
annotation: SIPFE06A7DA00AA80A5
annotation: SIP88552EBCF3553EA4
annotation: SIP3F788A390E6DE823
annotation: PRO_0000417088
annotation: SIPB021EC26D1124D6A
annotation: SIP9F1D852CA80A124C
annotation: SIP18005BC1B6416B37
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003677
classified with: GO_0004520
classified with: GO_0046872
classified with: GO_0051607
classified with: GO_0043571
sequence: B5YIU9-1
proteome: Chromosome

B5YIU9-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

PTHR43219:SF2
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDONUCLEASE CAS1
signature sequence match: PANTHER PTHR43219:SF2 match 1

SIP204C55B0F13AD9DB
type: Structured Name
full name: CRISPR-associated endonuclease Cas1 3
ec name: 3.1.-.-

cas1-3
type: Gene
alternative label: cas1_2
locus name: THEYE_A2036

SIPEFADA6A22BAA4FB4
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIP88552EBCF3553EA4
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas2 homodimer.

SIP3F788A390E6DE823
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endonuclease Cas1 family.

PRO_0000417088
type: Chain Annotation
comment: CRISPR-associated endonuclease Cas1 3
mass: 38754
range: 18636006061586734tt1tt325

18636006061586734tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIU9-1

18636006061586734tt325
type: Position
type: ExactPosition
position: 325
reference: B5YIU9-1

18636006061586734tt152
type: Position
type: ExactPosition
position: 152
reference: B5YIU9-1

18636006061586734tt217
type: Position
type: ExactPosition
position: 217
reference: B5YIU9-1

18636006061586734tt232
type: Position
type: ExactPosition
position: 232
reference: B5YIU9-1

B5YIU9-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 38754
value: MRNYYIFSNGRIRRKENTIYIENEQGDRKAIPIEDVDTIHIFGEVDLNTKLLNFICQQGKTVHFYNYYGFYSGSLMPRERNVSGHIVVKQVEHFLDPERRFYLAYSFVEGAIFHMVRNLREYKNTDEFQEKIKKELSNAVETTKISELMGCEGRARDFYYEAFNTFLKSDFSMGKREKRPPRNPINALISFANSMIYTTVLNEIYHTQLNPTVSYLHEPSERRYSLSLDIAEIFKPLLADAIIFKLINNNMIKLDDFEEDVNYCYLNESGRKKFIREFDQKLSTTIKHRKLKRNVSYRTIIRIECYKLIKHFIGDEVYAPFKAWW

http://purl.uniprot.org/uniprot/B5YIU9#attribution-1E5D5B72DE6977837297A311880B82C9
manual: true
evidence: ECO_0000255
source: MF_01470

B5YJS1
type: Protein
reviewed: true
created: 2012-06-13
modified: 2023-05-03
version: 66
mnemonic: CAS2A_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPD9F0BE9A01A7A5D4
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP326782A2B8E98F0B
annotation: SIP593AEFD78FC716C4
annotation: SIP19DD97BF5BD63D60
annotation: SIPFF47E63630D5F26F
annotation: PRO_0000417737
annotation: SIP4F28EE80699B13EF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046872
classified with: GO_0004521
classified with: GO_0051607
classified with: GO_0043571
sequence: MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG
proteome: Chromosome

B5YJS1-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1343
type: Resource
database: eggNOG
comment: Bacteria

cd09725
type: Resource
database: CDD
comment: Cas2_I_II_III
signature sequence match: CDD cd09725 match 1

MF_01471
type: Resource
database: HAMAP
comment: Cas2
signature sequence match: HAMAP MF 01471 match 1

IPR021127
type: Resource
database: InterPro
comment: CRISPR_associated_Cas2

IPR019199
type: Resource
database: InterPro
comment: Virulence_VapD/CRISPR_Cas2

PTHR34405
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS2
signature sequence match: PANTHER PTHR34405 match 1

PTHR34405:SF3
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS2 3
signature sequence match: PANTHER PTHR34405:SF3 match 1

PF09827
type: Resource
database: Pfam
comment: CRISPR_Cas2
signature sequence match: Pfam PF09827 match 1

SSF143430
type: Resource
database: SUPFAM
comment: TTP0101/SSO1404-like
signature sequence match: SUPFAM SSF143430 match 1

TIGR01573
type: Resource
database: TIGRFAMs
comment: cas2
signature sequence match: TIGRFAMs TIGR01573 match 1

SIPD9F0BE9A01A7A5D4
type: Structured Name
full name: CRISPR-associated endoribonuclease Cas2 1
ec name: 3.1.-.-

cas2-1
type: Gene
locus name: THEYE_A0643

SIP326782A2B8E98F0B
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIP19DD97BF5BD63D60
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas1 homodimer.

SIPFF47E63630D5F26F
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.

PRO_0000417737
type: Chain Annotation
comment: CRISPR-associated endoribonuclease Cas2 1
mass: 10802
range: 18636006078230830tt1tt92

18636006078230830tt1
type: Position
type: ExactPosition
position: 1
reference: MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG

18636006078230830tt92
type: Position
type: ExactPosition
position: 92
reference: MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG

18636006078230830tt10
type: Position
type: ExactPosition
position: 10
reference: MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG

SIP3C9371C25618D0A6
subclass of: CHEBI_18420
comment: catalytic

MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 10802

http://purl.uniprot.org/uniprot/B5YJS1#attribution-7C5673A0680FCFC8F90B5740087391F4
manual: true
evidence: ECO_0000255
source: MF_01471

B5YJS4
type: Protein
reviewed: true
created: 2012-06-13
modified: 2023-05-03
version: 65
mnemonic: CAS2B_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP7358C2D44276320B
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP20C048DD99EE7F6E
annotation: SIP8A508D3F7251E5F5
annotation: SIP55B640BBCD7ACAA3
annotation: SIPF8B0EB75E695DD66
annotation: PRO_0000417736
annotation: SIP6CB88CBD0D3FF97B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046872
classified with: GO_0004521
classified with: GO_0051607
classified with: GO_0043571
sequence: MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY
proteome: Chromosome

B5YJS4-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

SIP7358C2D44276320B
type: Structured Name
full name: CRISPR-associated endoribonuclease Cas2 2
ec name: 3.1.-.-

cas2-2
type: Gene
locus name: THEYE_A0646

SIP20C048DD99EE7F6E
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIP55B640BBCD7ACAA3
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas1 homodimer.

SIPF8B0EB75E695DD66
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.

PRO_0000417736
type: Chain Annotation
comment: CRISPR-associated endoribonuclease Cas2 2
mass: 10679
range: 18636006078231598tt1tt91

18636006078231598tt1
type: Position
type: ExactPosition
position: 1
reference: MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY

18636006078231598tt91
type: Position
type: ExactPosition
position: 91
reference: MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY

18636006078231598tt10
type: Position
type: ExactPosition
position: 10
reference: MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY

SIP3C9371C25618D0A6
subclass of: CHEBI_18420
comment: catalytic

MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 10679

http://purl.uniprot.org/uniprot/B5YJS4#attribution-7C5673A0680FCFC8F90B5740087391F4
manual: true
evidence: ECO_0000255
source: MF_01471

B5YIU7
type: Protein
reviewed: true
created: 2012-06-13
modified: 2023-05-03
version: 64
mnemonic: CAS2C_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP803C833A3BC3B952
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPB69C97003E2B874C
annotation: SIP96A51917A97EA221
annotation: SIP50B2B459C90754EC
annotation: SIP32F26BC4A5EABAA5
annotation: PRO_0000417735
annotation: SIP33B58FB21703D586
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/51
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046872
classified with: GO_0004521
classified with: GO_0051607
classified with: GO_0043571
sequence: MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL
proteome: Chromosome

B5YIU7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

PTHR34405:SF1
type: Resource
database: PANTHER
comment: CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS2
signature sequence match: PANTHER PTHR34405:SF1 match 1

SIP803C833A3BC3B952
type: Structured Name
full name: CRISPR-associated endoribonuclease Cas2 3
ec name: 3.1.-.-

cas2-3
type: Gene
locus name: THEYE_A2034

SIPB69C97003E2B874C
type: Function Annotation
comment: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.

SIP50B2B459C90754EC
type: Subunit Annotation
comment: Homodimer, forms a heterotetramer with a Cas1 homodimer.

SIP32F26BC4A5EABAA5
type: Similarity Annotation
comment: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.

PRO_0000417735
type: Chain Annotation
comment: CRISPR-associated endoribonuclease Cas2 3
mass: 10480
range: 18636006061586222tt1tt88

18636006061586222tt1
type: Position
type: ExactPosition
position: 1
reference: MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL

18636006061586222tt88
type: Position
type: ExactPosition
position: 88
reference: MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL

18636006061586222tt9
type: Position
type: ExactPosition
position: 9
reference: MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL

SIP3C9371C25618D0A6
subclass of: CHEBI_18420
comment: catalytic

MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 10480

http://purl.uniprot.org/uniprot/B5YIU7#attribution-7C5673A0680FCFC8F90B5740087391F4
manual: true
evidence: ECO_0000255
source: MF_01471

B5YJN4
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 72
mnemonic: CH10_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPFDB43817E50FCF12
alternative name: SIP2774763869FB9103
alternative name: SIP5D535EA69F0EC691
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPEE1CD4081E75FD20
annotation: SIPC11CD7028DAD7EED
annotation: SIP26F20D072641B8CA
annotation: SIPE31A4A752C1CB307
annotation: PRO_1000129721
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0046872
classified with: GO_0044183
classified with: GO_0051087
classified with: GO_0051082
classified with: GO_0051085
sequence: MKIKPLKDRVVVKFSSEELEKTPGGIYVPDVAKEKPQKGTVVEIGSEVKEVKVGDTVLFDKYAGSKIKVDDVEYLIIKEEEILGIVEK
proteome: Chromosome

B5YJN4-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0234
type: Resource
database: eggNOG
comment: Bacteria

cd00320
type: Resource
database: CDD
comment: cpn10
signature sequence match: CDD cd00320 match 1

http://purl.uniprot.org/gene3d/2.30.33.40
type: Resource
database: Gene3D
comment: GroES chaperonin
signature sequence match: Gene3D 2.30.33.40 match 1

MF_00580
type: Resource
database: HAMAP
comment: CH10
signature sequence match: HAMAP MF 00580 match 1

IPR020818
type: Resource
database: InterPro
comment: Chaperonin_GroES

IPR037124
type: Resource
database: InterPro
comment: Chaperonin_GroES_sf

IPR011032
type: Resource
database: InterPro
comment: GroES-like_sf

PTHR10772:SF58
type: Resource
database: PANTHER
comment: 10 KDA CHAPERONIN
signature sequence match: PANTHER PTHR10772:SF58 match 1

PTHR10772
type: Resource
database: PANTHER
comment: 10 KDA HEAT SHOCK PROTEIN
signature sequence match: PANTHER PTHR10772 match 1

PF00166
type: Resource
database: Pfam
comment: Cpn10
signature sequence match: Pfam PF00166 match 1

PR00297
type: Resource
database: PRINTS
comment: CHAPERONIN10

SM00883
type: Resource
database: SMART
comment: Cpn10
signature sequence match: SMART SM00883 match 1

SSF50129
type: Resource
database: SUPFAM
comment: GroES-like
signature sequence match: SUPFAM SSF50129 match 1

SIPFDB43817E50FCF12
type: Structured Name
full name: Co-chaperonin GroES

SIP2774763869FB9103
type: Structured Name
full name: 10 kDa chaperonin

SIP5D535EA69F0EC691
type: Structured Name
full name: Chaperonin-10
short name: Cpn10

groES
type: Gene
alternative label: groS
locus name: THEYE_A0606

SIPEE1CD4081E75FD20
type: Function Annotation
comment: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

SIPC11CD7028DAD7EED
type: Subunit Annotation
comment: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.

SIPE31A4A752C1CB307
type: Similarity Annotation
comment: Belongs to the GroES chaperonin family.

PRO_1000129721
type: Chain Annotation
comment: Co-chaperonin GroES
mass: 9820
range: 18636006077903918tt1tt88

18636006077903918tt1
type: Position
type: ExactPosition
position: 1
reference: MKIKPLKDRVVVKFSSEELEKTPGGIYVPDVAKEKPQKGTVVEIGSEVKEVKVGDTVLFDKYAGSKIKVDDVEYLIIKEEEILGIVEK

18636006077903918tt88
type: Position
type: ExactPosition
position: 88
reference: MKIKPLKDRVVVKFSSEELEKTPGGIYVPDVAKEKPQKGTVVEIGSEVKEVKVGDTVLFDKYAGSKIKVDDVEYLIIKEEEILGIVEK

MKIKPLKDRVVVKFSSEELEKTPGGIYVPDVAKEKPQKGTVVEIGSEVKEVKVGDTVLFDKYAGSKIKVDDVEYLIIKEEEILGIVEK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 9820

http://purl.uniprot.org/uniprot/B5YJN4#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJN4#attribution-BE67A4551C804FD86CAC41C18705626C
manual: true
evidence: ECO_0000255
source: MF_00580

B5YJN3
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 76
mnemonic: CH60_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPF255B4347D4E348A
alternative name: SIPE5C33196A30979CA
alternative name: SIPE325E657B082D974
enzyme: http://purl.uniprot.org/enzyme/5.6.1.7
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP2CBDE1CAF26D2CCE
annotation: SIP7385DA4D3019F06B
annotation: SIP8D18A16031B61742
annotation: SIPE2E2A3FCAF264241
annotation: SIP7B3387476CCD86C3
annotation: PRO_1000130073
annotation: SIPECB8967C3D4BE92A
annotation: SIP0D481A6A7CDDA1B6
annotation: SIP51AD87DBE8FBC79A
annotation: SIP0D3E879E321A8218
annotation: SIPE18F6F0437527180
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_1990220
classified with: GO_0005524
classified with: GO_0140662
classified with: GO_0016853
classified with: GO_0051082
classified with: GO_0051085
classified with: GO_0042026
classified with: GO_0009408
sequence: B5YJN3-1
proteome: Chromosome

B5YJN3-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0459
type: Resource
database: eggNOG
comment: Bacteria

cd03344
type: Resource
database: CDD
comment: GroEL
signature sequence match: CDD cd03344 match 1

http://purl.uniprot.org/gene3d/3.50.7.10
type: Resource
database: Gene3D
comment: GroEL
signature sequence match: Gene3D 3.50.7.10 match 1

http://purl.uniprot.org/gene3d/1.10.560.10
type: Resource
database: Gene3D
comment: GroEL-like equatorial domain
signature sequence match: Gene3D 1.10.560.10 match 1

http://purl.uniprot.org/gene3d/3.30.260.10
type: Resource
database: Gene3D
comment: TCP-1-like chaperonin intermediate domain
signature sequence match: Gene3D 3.30.260.10 match 1

MF_00600
type: Resource
database: HAMAP
comment: CH60
signature sequence match: HAMAP MF 00600 match 1

IPR018370
type: Resource
database: InterPro
comment: Chaperonin_Cpn60_CS

IPR001844
type: Resource
database: InterPro
comment: Cpn60/GroEL

IPR002423
type: Resource
database: InterPro
comment: Cpn60/GroEL/TCP-1

IPR027409
type: Resource
database: InterPro
comment: GroEL-like_apical_dom_sf

IPR027413
type: Resource
database: InterPro
comment: GROEL-like_equatorial_sf

IPR027410
type: Resource
database: InterPro
comment: TCP-1-like_intermed_sf

PTHR45633
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633 match 1

PTHR45633:SF3
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633:SF3 match 1

PF00118
type: Resource
database: Pfam
comment: Cpn60_TCP1
signature sequence match: Pfam PF00118 match 1

PR00298
type: Resource
database: PRINTS
comment: CHAPERONIN60

SSF52029
type: Resource
database: SUPFAM
comment: GroEL apical domain-like
signature sequence match: SUPFAM SSF52029 match 1

SSF48592
type: Resource
database: SUPFAM
comment: GroEL equatorial domain-like
signature sequence match: SUPFAM SSF48592 match 1

SSF54849
type: Resource
database: SUPFAM
comment: GroEL-intermediate domain like
signature sequence match: SUPFAM SSF54849 match 1

TIGR02348
type: Resource
database: TIGRFAMs
comment: GroEL
signature sequence match: TIGRFAMs TIGR02348 match 1

PS00296
type: Resource
database: PROSITE
comment: CHAPERONINS_CPN60
signature sequence match: PROSITE PS00296 match 1

SIPF255B4347D4E348A
type: Structured Name
full name: Chaperonin GroEL
ec name: 5.6.1.7

SIPE5C33196A30979CA
type: Structured Name
full name: 60 kDa chaperonin

SIPE325E657B082D974
type: Structured Name
full name: Chaperonin-60
short name: Cpn60

groEL
type: Gene
alternative label: groL
locus name: THEYE_A0605

SIP2CBDE1CAF26D2CCE
type: Function Annotation
comment: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

SIP8D18A16031B61742
type: Subunit Annotation
comment: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

SIP7B3387476CCD86C3
type: Similarity Annotation
comment: Belongs to the chaperonin (HSP60) family.

PRO_1000130073
type: Chain Annotation
comment: Chaperonin GroEL
mass: 58406
range: 18636006077903662tt1tt540

18636006077903662tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJN3-1

18636006077903662tt540
type: Position
type: ExactPosition
position: 540
reference: B5YJN3-1

18636006077903662tt30
type: Position
type: ExactPosition
position: 30
reference: B5YJN3-1

18636006077903662tt33
type: Position
type: ExactPosition
position: 33
reference: B5YJN3-1

18636006077903662tt51
type: Position
type: ExactPosition
position: 51
reference: B5YJN3-1

18636006077903662tt87
type: Position
type: ExactPosition
position: 87
reference: B5YJN3-1

18636006077903662tt91
type: Position
type: ExactPosition
position: 91
reference: B5YJN3-1

18636006077903662tt415
type: Position
type: ExactPosition
position: 415
reference: B5YJN3-1

18636006077903662tt496
type: Position
type: ExactPosition
position: 496
reference: B5YJN3-1

B5YJN3-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 58406
value: MAAKQLIFGDAARQSILKGVTLLTDAVKATLGPRGRNVVIERKFGSPNVTKDGVTVAKEIDLKEPFENMGAQLVREVASKTSDVAGDGTTTATVLAYAIYKEGLKYVSAGANSMDLKRGIDKAVEAVVEELKKISKPVVDKKEIAQVGTISANNDVSIGELIAEAMDKVGKDGVITVEEAKGMATTLDIVEGMQFDRGYISPYFITDPERLECILEDAFVLIHDKKISTMKDLLPILEQIARMGRPLLIIAEDVEGEALATLVVNKLRGVLQVCAVKAPGFGERRKAMLEDIAILTGGTVISEDIGLKLENVKVEDLGKAKKIIIDKDNTTIVEGAGDPQKIQARIKQIKVQIDETTSDYDREKLQERLAKLAGGVARINVGAATEAEMKEKKARVEDALNATRAAVEEGIVPGGGVALLRCQKALEKIKFENHDQQLGAEIVKKALEEPIKQIIANAGVEATLIVEKVKENKNINYGYDAYAEKFVDMMEAGIIDPTKVTRTALQNAASVAGLMLTTEVLVAEIPEEEKKPPMPSPDMY

http://purl.uniprot.org/uniprot/B5YJN3#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJN3#attribution-2F1A0E67B478851653C1AADDD6958B54
manual: true
evidence: ECO_0000255
source: MF_00600

B5YI38
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 80
mnemonic: CLPP_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP07EC96E90BC5B0F2
alternative name: SIP7353D1C153228504
enzyme: http://purl.uniprot.org/enzyme/3.4.21.92
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPC3F62AD0582131E1
annotation: SIPAC74AFC872AB8C66
annotation: SIP63926B3C374DD4B8
annotation: SIP13415212658FE627
annotation: SIP4AE2AA8BABBA91A7
annotation: PRO_1000124721
annotation: SIP2F20020062B124F5
annotation: SIPD08B32B4C3BD9124
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/720
classified with: GO_0005737
classified with: GO_0009368
classified with: GO_0004176
classified with: GO_0051117
classified with: GO_0004252
classified with: GO_0006515
sequence: MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK
proteome: Chromosome

B5YI38-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0740
type: Resource
database: eggNOG
comment: Bacteria

cd07017
type: Resource
database: CDD
comment: S14_ClpP_2
signature sequence match: CDD cd07017 match 1

MF_00444
type: Resource
database: HAMAP
comment: ClpP
signature sequence match: HAMAP MF 00444 match 1

IPR001907
type: Resource
database: InterPro
comment: ClpP

IPR023562
type: Resource
database: InterPro
comment: ClpP/TepA

IPR033135
type: Resource
database: InterPro
comment: ClpP_His_AS

PTHR10381
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT
signature sequence match: PANTHER PTHR10381 match 1

PTHR10381:SF70
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT
signature sequence match: PANTHER PTHR10381:SF70 match 1

PF00574
type: Resource
database: Pfam
comment: CLP_protease
signature sequence match: Pfam PF00574 match 1

PR00127
type: Resource
database: PRINTS
comment: CLPPROTEASEP

TIGR00493
type: Resource
database: TIGRFAMs
comment: clpP
signature sequence match: TIGRFAMs TIGR00493 match 1

PS00382
type: Resource
database: PROSITE
comment: CLP_PROTEASE_HIS
signature sequence match: PROSITE PS00382 match 1

SIP07EC96E90BC5B0F2
type: Structured Name
full name: ATP-dependent Clp protease proteolytic subunit
ec name: 3.4.21.92

SIP7353D1C153228504
type: Structured Name
full name: Endopeptidase Clp

clpP
type: Gene
locus name: THEYE_A0255

SIPC3F62AD0582131E1
type: Function Annotation
comment: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.

SIP63926B3C374DD4B8
type: Subunit Annotation
comment: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIP4AE2AA8BABBA91A7
type: Similarity Annotation
comment: Belongs to the peptidase S14 family.

PRO_1000124721
type: Chain Annotation
comment: ATP-dependent Clp protease proteolytic subunit
mass: 21783
range: 18636006059358254tt1tt195

18636006059358254tt1
type: Position
type: ExactPosition
position: 1
reference: MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK

18636006059358254tt195
type: Position
type: ExactPosition
position: 195
reference: MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK

SIP2F20020062B124F5
type: Active Site Annotation
comment: Nucleophile
range: 18636006059358254tt98tt98

18636006059358254tt98
type: Position
type: ExactPosition
position: 98
reference: MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK

18636006059358254tt123
type: Position
type: ExactPosition
position: 123
reference: MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK

MSIVPIVIEQTGRTERVYDIYSRLLKDRIIFIGTEINDHVANVVIAQLLFLQTEDPEKDIHIYINSPGGMVSSGLAIYDTMQYVKPDIATYCIGQASSMACVLLAAGTKGKRFALPHSRVMIHQPIGGFYGQATDVEIHAKEILKMKDLLNNILAKHTGQPIEKIQKDTERDFFMSAEEAKLYGIVDEVISSIKK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 21783

http://purl.uniprot.org/uniprot/B5YI38#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI38#attribution-83FF83956DB918F871897D2ABDA0D60B
manual: true
evidence: ECO_0000255
source: MF_00444

B5YI39
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 88
mnemonic: CLPX_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPF43CC31C6B90A8EC
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPB3B106D82364AC9E
annotation: SIP769DBDE3A58D8E27
annotation: SIP7CCFBEAE0D5B83BB
annotation: PRO_1000123857
annotation: SIP71C9CCB5986E0867
annotation: SIP28E1FF54FBD7E23C
annotation: SIP321E9A6A78291033
annotation: SIPC5BD6E753F4F41E8
annotation: SIP630CBB020D73A0E0
annotation: SIP675216CCF5D3EE96
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0009376
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0046983
classified with: GO_0051082
classified with: GO_0008270
classified with: GO_0051301
classified with: GO_0051603
sequence: B5YI39-1
proteome: Chromosome

B5YI39-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1219
type: Resource
database: eggNOG
comment: Bacteria

cd19497
type: Resource
database: CDD
comment: RecA-like_ClpX
signature sequence match: CDD cd19497 match 1

http://purl.uniprot.org/gene3d/6.20.220.10
type: Resource
database: Gene3D
comment: ClpX chaperone, C4-type zinc finger domain
signature sequence match: Gene3D 6.20.220.10 match 1

MF_00175
type: Resource
database: HAMAP
comment: ClpX
signature sequence match: HAMAP MF 00175 match 1

IPR003959
type: Resource
database: InterPro
comment: ATPase_AAA_core

IPR019489
type: Resource
database: InterPro
comment: Clp_ATPase_C

IPR004487
type: Resource
database: InterPro
comment: Clp_protease_ATP-bd_su_ClpX

IPR046425
type: Resource
database: InterPro
comment: ClpX_bact

IPR010603
type: Resource
database: InterPro
comment: Znf_CppX_C4

IPR038366
type: Resource
database: InterPro
comment: Znf_CppX_C4_sf

PTHR48102:SF7
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48102:SF7 match 1

PTHR48102
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED
signature sequence match: PANTHER PTHR48102 match 1

PF07724
type: Resource
database: Pfam
comment: AAA_2
signature sequence match: Pfam PF07724 match 1

PF10431
type: Resource
database: Pfam
comment: ClpB_D2-small
signature sequence match: Pfam PF10431 match 1

PF06689
type: Resource
database: Pfam
comment: zf-C4_ClpX
signature sequence match: Pfam PF06689 match 1

SM01086
type: Resource
database: SMART
comment: ClpB_D2-small
signature sequence match: SMART SM01086 match 1

SM00994
type: Resource
database: SMART
comment: zf-C4_ClpX
signature sequence match: SMART SM00994 match 1

SSF57716
type: Resource
database: SUPFAM
comment: Glucocorticoid receptor-like (DNA-binding domain)
signature sequence match: SUPFAM SSF57716 match 1

TIGR00382
type: Resource
database: TIGRFAMs
comment: clpX
signature sequence match: TIGRFAMs TIGR00382 match 1

PS51902
type: Resource
database: PROSITE
comment: CLPX_ZB
signature sequence match: PROSITE PS51902 match 1

SIPF43CC31C6B90A8EC
type: Structured Name
full name: ATP-dependent Clp protease ATP-binding subunit ClpX

clpX
type: Gene
locus name: THEYE_A0256

SIPB3B106D82364AC9E
type: Function Annotation
comment: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.

SIP769DBDE3A58D8E27
type: Subunit Annotation
comment: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIP7CCFBEAE0D5B83BB
type: Similarity Annotation
comment: Belongs to the ClpX chaperone family.

PRO_1000123857
type: Chain Annotation
comment: ATP-dependent Clp protease ATP-binding subunit ClpX
mass: 45754
range: 18636006059358510tt1tt409

18636006059358510tt1
type: Position
type: ExactPosition
position: 1
reference: B5YI39-1

18636006059358510tt409
type: Position
type: ExactPosition
position: 409
reference: B5YI39-1

SIP71C9CCB5986E0867
type: Domain Extent Annotation
comment: ClpX-type ZB
range: 18636006059358510tt1tt52

18636006059358510tt52
type: Position
type: ExactPosition
position: 52
reference: B5YI39-1

18636006059358510tt11
type: Position
type: ExactPosition
position: 11
reference: B5YI39-1

18636006059358510tt14
type: Position
type: ExactPosition
position: 14
reference: B5YI39-1

18636006059358510tt33
type: Position
type: ExactPosition
position: 33
reference: B5YI39-1

18636006059358510tt36
type: Position
type: ExactPosition
position: 36
reference: B5YI39-1

18636006059358510tt113
type: Position
type: ExactPosition
position: 113
reference: B5YI39-1

18636006059358510tt120
type: Position
type: ExactPosition
position: 120
reference: B5YI39-1

B5YI39-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 45754
value: MAKKNEETLRCSFCGKSQKEVKKLIAGNGVYICDECVSLCNEILEEERFEHLEGIKQDLPTPQEIHKFLNDYVIGQERAKKILSVAVYNHYKRIFKGTSSDEIQKSNIMLIGPTGTGKTLLAQTLAKFLDVPFAIADATTLTEAGYVGEDVENILLKLLQNANFDIQRAQIGIIYIDEIDKISRKSDSPSITRDVSGEGVQQALLKIVEGTLANIPPQGGRKHPQQEYIQLDTTNILFICGGAFVGLEEIIKKRIGKRTIGFLSETKKIDEENVLSQAEPEDLIKYGMIPEFVGRFPVVATLNQLDEDALIEILTKPKNALVKQYQKLFSIDGVKLTFTDDALRAIAKKAIERKTGARALRSILEDIMLDVMYLIPSERGINECIINEDVVNKKASPILIYKEKKVKHA

http://purl.uniprot.org/uniprot/B5YI39#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI39#attribution-CFB06F30A19C652E3C2E44B930DCAAA4
manual: true
evidence: ECO_0000255
source: MF_00175

http://purl.uniprot.org/uniprot/B5YI39#attribution-53EBA6D767FE97D40C9959E24A2E919D
manual: true
evidence: ECO_0000255
source: PRU01250

B5YK79
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 77
mnemonic: COAD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPF6F66FCD23803F87
alternative name: SIPCEC148E019BD360F
alternative name: SIP35682BD6712EB9F8
enzyme: http://purl.uniprot.org/enzyme/2.7.7.3
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP3A19230305DC8CFE
annotation: SIP97C2E5ABAF2F5218
annotation: SIPDB406EAB805FA1EC
annotation: SIPA3FDF84B536CFBE7
annotation: SIP4549EAFC1F9438B2
annotation: SIPAC4C1FE3812E11F2
annotation: SIP80AC9545F8569FD2
annotation: PRO_1000118086
annotation: SIPFAA52D88DF5FB5DC
annotation: SIP2EB9A692C09F9C03
annotation: SIP8090097746E237F0
annotation: SIPC3C310585DE58708
annotation: SIP5F98AE0BA2DE740A
annotation: SIP37E27CDC83ECF868
annotation: SIPA2EB4BA47BD626C4
annotation: SIPA07171C198C5AC57
annotation: SIPA0A7E1FA7F79827F
annotation: SIP0A954A80ACB45ACC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/173
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0004595
classified with: GO_0015937
sequence: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK
proteome: Chromosome

B5YK79-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0669
type: Resource
database: eggNOG
comment: Bacteria

cd02163
type: Resource
database: CDD
comment: PPAT
signature sequence match: CDD cd02163 match 1

http://purl.uniprot.org/gene3d/3.40.50.620
type: Resource
database: Gene3D
comment: HUPs
signature sequence match: Gene3D 3.40.50.620 match 1

MF_00151
type: Resource
database: HAMAP
comment: PPAT_bact
signature sequence match: HAMAP MF 00151 match 1

IPR004821
type: Resource
database: InterPro
comment: Cyt_trans-like

IPR001980
type: Resource
database: InterPro
comment: PPAT

IPR014729
type: Resource
database: InterPro
comment: Rossmann-like_a/b/a_fold

PTHR21342
type: Resource
database: PANTHER
comment: PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
signature sequence match: PANTHER PTHR21342 match 1

PTHR21342:SF1
type: Resource
database: PANTHER
comment: PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
signature sequence match: PANTHER PTHR21342:SF1 match 1

PF01467
type: Resource
database: Pfam
comment: CTP_transf_like
signature sequence match: Pfam PF01467 match 1

PR01020
type: Resource
database: PRINTS
comment: LPSBIOSNTHSS

SSF52374
type: Resource
database: SUPFAM
comment: Nucleotidylyl transferase
signature sequence match: SUPFAM SSF52374 match 1

TIGR01510
type: Resource
database: TIGRFAMs
comment: coaD_prev_kdtB
signature sequence match: TIGRFAMs TIGR01510 match 1

TIGR00125
type: Resource
database: TIGRFAMs
comment: cyt_tran_rel
signature sequence match: TIGRFAMs TIGR00125 match 1

SIPF6F66FCD23803F87
type: Structured Name
full name: Phosphopantetheine adenylyltransferase
ec name: 2.7.7.3

SIPCEC148E019BD360F
type: Structured Name
full name: Dephospho-CoA pyrophosphorylase

SIP35682BD6712EB9F8
type: Structured Name
full name: Pantetheine-phosphate adenylyltransferase
short name: PPAT

coaD
type: Gene
locus name: THEYE_A0803

SIP3A19230305DC8CFE
type: Function Annotation
comment: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

SIP4549EAFC1F9438B2
type: Subunit Annotation
comment: Homohexamer.

SIP80AC9545F8569FD2
type: Similarity Annotation
comment: Belongs to the bacterial CoaD family.

PRO_1000118086
type: Chain Annotation
comment: Phosphopantetheine adenylyltransferase
mass: 18300
range: 18636006093175086tt1tt161

18636006093175086tt1
type: Position
type: ExactPosition
position: 1
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt161
type: Position
type: ExactPosition
position: 161
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt10
type: Position
type: ExactPosition
position: 10
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt11
type: Position
type: ExactPosition
position: 11
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt18
type: Position
type: ExactPosition
position: 18
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt42
type: Position
type: ExactPosition
position: 42
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt75
type: Position
type: ExactPosition
position: 75
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt89
type: Position
type: ExactPosition
position: 89
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt90
type: Position
type: ExactPosition
position: 90
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt92
type: Position
type: ExactPosition
position: 92
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt100
type: Position
type: ExactPosition
position: 100
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt125
type: Position
type: ExactPosition
position: 125
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

18636006093175086tt131
type: Position
type: ExactPosition
position: 131
reference: MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK

SIP0A954A80ACB45ACC
type: Site Annotation
comment: Transition state stabilizer
range: 18636006093175086tt18tt18

substrate

MTKTGVYPGTFDPITNGHLDVIKRALKIFDELIVAVAMSSYKKTPIFTVEERVHFIAQTTKDLKNLKVEVFDGLLVNFIKEKKAVAIVRGLRAVSDYEFELQLAHANRRLFRDIETVFLMPSEEYSFLSSSLVKEIAYFGGSVKSLVPPIVEKALRNKFKK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 18300

http://purl.uniprot.org/uniprot/B5YK79#attribution-1FBF028CE5C20B3CECCC520D3E79044A
manual: true
evidence: ECO_0000255
source: MF_00151

B5YL83
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 75
mnemonic: COBQ_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP1F22C1FD7104CE3A
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPDEAF66D2D085AAFC
annotation: SIP664B06F6E87CAB74
annotation: SIP58EBD6FB335128A8
annotation: PRO_1000090251
annotation: SIPCC68A3460D87C759
annotation: SIP324E22838A72FF6F
annotation: SIP8FDDBE1032DBF5DD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/315
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0015420
classified with: GO_0003824
classified with: GO_0009236
classified with: GO_0006541
sequence: B5YL83-1
proteome: Chromosome

B5YL83-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1492
type: Resource
database: eggNOG
comment: Bacteria

cd05389
type: Resource
database: CDD
comment: CobQ_N
signature sequence match: CDD cd05389 match 1

cd01750
type: Resource
database: CDD
comment: GATase1_CobQ
signature sequence match: CDD cd01750 match 1

MF_00028
type: Resource
database: HAMAP
comment: CobQ
signature sequence match: HAMAP MF 00028 match 1

IPR029062
type: Resource
database: InterPro
comment: Class_I_gatase-like

IPR002586
type: Resource
database: InterPro
comment: CobQ/CobB/MinD/ParA_Nub-bd_dom

IPR033949
type: Resource
database: InterPro
comment: CobQ_GATase1

IPR047045
type: Resource
database: InterPro
comment: CobQ_N

IPR004459
type: Resource
database: InterPro
comment: CobQ_synth

IPR011698
type: Resource
database: InterPro
comment: GATase_3

PTHR21343:SF1
type: Resource
database: PANTHER
comment: COBYRIC ACID SYNTHASE
signature sequence match: PANTHER PTHR21343:SF1 match 1

PTHR21343
type: Resource
database: PANTHER
comment: DETHIOBIOTIN SYNTHETASE
signature sequence match: PANTHER PTHR21343 match 1

PF01656
type: Resource
database: Pfam
comment: CbiA
signature sequence match: Pfam PF01656 match 1

PF07685
type: Resource
database: Pfam
comment: GATase_3
signature sequence match: Pfam PF07685 match 1

SSF52317
type: Resource
database: SUPFAM
comment: Class I glutamine amidotransferase-like
signature sequence match: SUPFAM SSF52317 match 1

TIGR00313
type: Resource
database: TIGRFAMs
comment: cobQ
signature sequence match: TIGRFAMs TIGR00313 match 1

PS51274
type: Resource
database: PROSITE
comment: GATASE_COBBQ
signature sequence match: PROSITE PS51274 match 1

SIP1F22C1FD7104CE3A
type: Structured Name
full name: Cobyric acid synthase

cobQ
type: Gene
locus name: THEYE_A1177

SIPDEAF66D2D085AAFC
type: Function Annotation
comment: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

SIP58EBD6FB335128A8
type: Similarity Annotation
comment: Belongs to the CobB/CobQ family. CobQ subfamily.

PRO_1000090251
type: Chain Annotation
comment: Cobyric acid synthase
mass: 55213
range: 18636006110016302tt1tt493

18636006110016302tt1
type: Position
type: ExactPosition
position: 1
reference: B5YL83-1

18636006110016302tt493
type: Position
type: ExactPosition
position: 493
reference: B5YL83-1

SIPCC68A3460D87C759
type: Domain Extent Annotation
comment: GATase cobBQ-type
range: 18636006110016302tt252tt440

18636006110016302tt252
type: Position
type: ExactPosition
position: 252
reference: B5YL83-1

18636006110016302tt440
type: Position
type: ExactPosition
position: 440
reference: B5YL83-1

SIP324E22838A72FF6F
type: Active Site Annotation
comment: Nucleophile
range: 18636006110016302tt333tt333

18636006110016302tt333
type: Position
type: ExactPosition
position: 333
reference: B5YL83-1

18636006110016302tt432
type: Position
type: ExactPosition
position: 432
reference: B5YL83-1

B5YL83-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 55213
value: MAKLLMIQGTSSNCGKSLIVTALCRITKNRGIKVAPFKAQNMSLQSFITEDGGEIGLAQAIQAEAAGVVPNVHMNPVLLKPSGQQGIQIVVHGKLYKTLNSIDFYSEKKKLWENVTDSLNYLLKEHDFLIIEGAGSPAEINLLEKDIVNMAVAEYLKAPVILVGDIDRGGVFASLYGTVKLLEKYDSLFKGFIINKFRGHVDILSPGIKKLEELINKPCLGVVPYLDETGISDEDGVSMRLINFFAQKVNAPVKIVVLRLRYISNFNDFEPLRFEPDTELMYSLKKEDLLSADIIIIPGSKKTFEDLKLLRELKIDQTLRELAKNGVEIIGICGGFQMLGEKLIDPYMVESSLREFDGIGLLPVETLFYPEKITTQVEGCLCSEPSIKITGYEIHKGITYGHLGLFKITRTSMNQTLFDGIVCGNVWGTYIHGIFESDSLRRWLINRHRVKKGLNPIDYSFSWKKLKESFIDTLANTIEKNLDINRVWEIAGL

http://purl.uniprot.org/uniprot/B5YL83#attribution-3EECC318250E032297AF9DA630730042
manual: true
evidence: ECO_0000255
source: MF_00028

B5YL84
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 77
mnemonic: COBS_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPC8F0476443F80643
alternative name: SIP15C415C9304BACEC
alternative name: SIPAAFD642635A00D3E
enzyme: http://purl.uniprot.org/enzyme/2.7.8.26
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP93636B7C48A21E59
annotation: SIP4364C9427FE40515
annotation: SIPB678D27F5140D8BB
annotation: SIP71E46C4486AA6618
annotation: SIP42382560FB2ED3D9
annotation: SIP32782F1C392BA40C
annotation: SIP8E56F45942DDE497
annotation: PRO_1000132612
annotation: SIPBC285BC520BA3FC9
annotation: SIP8FEC8238E5697DDF
annotation: SIP19D962D3C87216D8
annotation: SIP238114666FC64EC5
annotation: SIP4AE94C422F72FD38
annotation: SIPB07BAE9F2D0C40BB
annotation: SIP5E1116C7C83D9F3B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/169
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0051073
classified with: GO_0008818
classified with: GO_0009236
sequence: B5YL84-1
proteome: Chromosome

B5YL84-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0368
type: Resource
database: eggNOG
comment: Bacteria

MF_00719
type: Resource
database: HAMAP
comment: CobS
signature sequence match: HAMAP MF 00719 match 1

IPR003805
type: Resource
database: InterPro
comment: CobS

PTHR34148
type: Resource
database: PANTHER
comment: ADENOSYLCOBINAMIDE-GDP RIBAZOLETRANSFERASE
signature sequence match: PANTHER PTHR34148 match 1

PTHR34148:SF1
type: Resource
database: PANTHER
comment: ADENOSYLCOBINAMIDE-GDP RIBAZOLETRANSFERASE
signature sequence match: PANTHER PTHR34148:SF1 match 1

PF02654
type: Resource
database: Pfam
comment: CobS
signature sequence match: Pfam PF02654 match 1

TIGR00317
type: Resource
database: TIGRFAMs
comment: cobS
signature sequence match: TIGRFAMs TIGR00317 match 1

SIPC8F0476443F80643
type: Structured Name
full name: Adenosylcobinamide-GDP ribazoletransferase
ec name: 2.7.8.26

SIP15C415C9304BACEC
type: Structured Name
full name: Cobalamin synthase

SIPAAFD642635A00D3E
type: Structured Name
full name: Cobalamin-5'-phosphate synthase

cobS
type: Gene
locus name: THEYE_A1178

SIP93636B7C48A21E59
type: Function Annotation
comment: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

SIP8E56F45942DDE497
type: Similarity Annotation
comment: Belongs to the CobS family.

PRO_1000132612
type: Chain Annotation
comment: Adenosylcobinamide-GDP ribazoletransferase
mass: 29998
range: 18636006110016558tt1tt260

18636006110016558tt1
type: Position
type: ExactPosition
position: 1
reference: B5YL84-1

18636006110016558tt260
type: Position
type: ExactPosition
position: 260
reference: B5YL84-1

SIPBC285BC520BA3FC9
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt31tt51

18636006110016558tt31
type: Position
type: ExactPosition
position: 31
reference: B5YL84-1

18636006110016558tt51
type: Position
type: ExactPosition
position: 51
reference: B5YL84-1

SIP8FEC8238E5697DDF
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt55tt75

18636006110016558tt55
type: Position
type: ExactPosition
position: 55
reference: B5YL84-1

18636006110016558tt75
type: Position
type: ExactPosition
position: 75
reference: B5YL84-1

SIP19D962D3C87216D8
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt111tt131

18636006110016558tt111
type: Position
type: ExactPosition
position: 111
reference: B5YL84-1

18636006110016558tt131
type: Position
type: ExactPosition
position: 131
reference: B5YL84-1

SIP238114666FC64EC5
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt140tt160

18636006110016558tt140
type: Position
type: ExactPosition
position: 140
reference: B5YL84-1

18636006110016558tt160
type: Position
type: ExactPosition
position: 160
reference: B5YL84-1

SIP4AE94C422F72FD38
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt177tt197

18636006110016558tt177
type: Position
type: ExactPosition
position: 177
reference: B5YL84-1

18636006110016558tt197
type: Position
type: ExactPosition
position: 197
reference: B5YL84-1

SIPB07BAE9F2D0C40BB
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt202tt222

18636006110016558tt202
type: Position
type: ExactPosition
position: 202
reference: B5YL84-1

18636006110016558tt222
type: Position
type: ExactPosition
position: 222
reference: B5YL84-1

SIP5E1116C7C83D9F3B
type: Transmembrane Annotation
comment: Helical
range: 18636006110016558tt234tt254

18636006110016558tt234
type: Position
type: ExactPosition
position: 234
reference: B5YL84-1

18636006110016558tt254
type: Position
type: ExactPosition
position: 254
reference: B5YL84-1

B5YL84-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 29998
value: MINRFLIALSFLTVLPLKFKEINEKELIRSIIFFPFIGFLEGVFCIFLVNIFKQIFSSSVISIILLVFLFSVRGIFHIDGLSDTFDALFYKGTGQKEKDLQQRLQIMKDSVIGVAGAVALVLDVLCRFAFVKELIDINQFLIFLFMFCFSRWIVIPLMYYGKPARTTGLGVLFIGKISSWQVIISTVLPIFLLVYFTIEKNFIFLPLIALFLFFISYILKKFFERKFNGITGDHLGATVEITEIVFLICFLLGEKLWLSY

http://purl.uniprot.org/uniprot/B5YL84#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YL84#attribution-F9FF836B4CDE0FA70381736F117C802A
manual: true
evidence: ECO_0000255
source: MF_00719

B5YJA6
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 78
mnemonic: CYSC_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPA7B1C1A582B5D83A
alternative name: SIPE7EF2B89C9B7C006
alternative name: SIPB41809F2CA33CD2E
alternative name: SIP66D8ACEE4AF1A34A
enzyme: http://purl.uniprot.org/enzyme/2.7.1.25
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPC4B1BC15E0C37FF3
annotation: SIP490EC1879C290304
annotation: SIP0F1D51B94EDD3175
annotation: SIPE62CAB33F404911A
annotation: PRO_1000117959
annotation: SIP385AB80ACB7E487D
annotation: SIPC78E5429301FD5C6
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004020
classified with: GO_0005524
classified with: GO_0070814
classified with: GO_0016310
classified with: GO_0000103
sequence: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL
proteome: Chromosome

B5YJA6-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0529
type: Resource
database: eggNOG
comment: Bacteria

cd02027
type: Resource
database: CDD
comment: APSK
signature sequence match: CDD cd02027 match 1

MF_00065
type: Resource
database: HAMAP
comment: Adenylyl_sulf_kinase
signature sequence match: HAMAP MF 00065 match 1

IPR002891
type: Resource
database: InterPro
comment: APS_kinase

PTHR11055:SF1
type: Resource
database: PANTHER
comment: 3'-PHOSPHOADENOSINE-5'-PHOSPHOSULFATE SYNTHASE
signature sequence match: PANTHER PTHR11055:SF1 match 1

PTHR11055
type: Resource
database: PANTHER
comment: BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE
signature sequence match: PANTHER PTHR11055 match 1

PF01583
type: Resource
database: Pfam
comment: APS_kinase
signature sequence match: Pfam PF01583 match 1

TIGR00455
type: Resource
database: TIGRFAMs
comment: apsK
signature sequence match: TIGRFAMs TIGR00455 match 1

SIPA7B1C1A582B5D83A
type: Structured Name
full name: Adenylyl-sulfate kinase
ec name: 2.7.1.25

SIPE7EF2B89C9B7C006
type: Structured Name
full name: APS kinase

SIPB41809F2CA33CD2E
type: Structured Name
full name: ATP adenosine-5'-phosphosulfate 3'-phosphotransferase

SIP66D8ACEE4AF1A34A
type: Structured Name
full name: Adenosine-5'-phosphosulfate kinase

cysC
type: Gene
locus name: THEYE_A0476

SIPC4B1BC15E0C37FF3
type: Function Annotation
comment: Catalyzes the synthesis of activated sulfate.

SIPE62CAB33F404911A
type: Similarity Annotation
comment: Belongs to the APS kinase family.

PRO_1000117959
type: Chain Annotation
comment: Adenylyl-sulfate kinase
mass: 23070
range: 18636006077052462tt1tt200

18636006077052462tt1
type: Position
type: ExactPosition
position: 1
reference: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL

18636006077052462tt200
type: Position
type: ExactPosition
position: 200
reference: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL

SIP385AB80ACB7E487D
type: Active Site Annotation
comment: Phosphoserine intermediate
range: 18636006077052462tt109tt109

18636006077052462tt109
type: Position
type: ExactPosition
position: 109
reference: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL

18636006077052462tt35
type: Position
type: ExactPosition
position: 35
reference: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL

18636006077052462tt42
type: Position
type: ExactPosition
position: 42
reference: MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL

MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 23070

http://purl.uniprot.org/uniprot/B5YJA6#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJA6#attribution-91A1F1551FA6A9D7B56CB2E8B282B495
manual: true
evidence: ECO_0000255
source: MF_00065

B5YKK4
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 74
mnemonic: DAPA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP3DCCD2FAF2A8502D
enzyme: http://purl.uniprot.org/enzyme/4.3.3.7
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPA550681A038742E6
annotation: SIP8946604B43527BDE
annotation: SIP3BBFCD97638DD228
annotation: SIP527C35B428B3C19C
annotation: SIP573FB7A2D8BAF3FB
annotation: SIPA4F512D06E2B1F98
annotation: SIP859630E68AF3293B
annotation: PRO_1000124078
annotation: SIPD3190A2F47C32F26
annotation: SIPA699B6B71A5E073F
annotation: SIP38D61F8EF115412E
annotation: SIP13206AAB2953A781
annotation: SIP6F4998024A7F388F
annotation: SIP0D821A93D0A7971C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0005829
classified with: GO_0008840
classified with: GO_0019877
classified with: GO_0009089
sequence: B5YKK4-1
proteome: Chromosome

B5YKK4-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0329
type: Resource
database: eggNOG
comment: Bacteria

cd00950
type: Resource
database: CDD
comment: DHDPS
signature sequence match: CDD cd00950 match 1

MF_00418
type: Resource
database: HAMAP
comment: DapA
signature sequence match: HAMAP MF 00418 match 1

IPR005263
type: Resource
database: InterPro
comment: DapA

IPR002220
type: Resource
database: InterPro
comment: DapA-like

IPR020625
type: Resource
database: InterPro
comment: Schiff_base-form_aldolases_AS

IPR020624
type: Resource
database: InterPro
comment: Schiff_base-form_aldolases_CS

PTHR12128:SF66
type: Resource
database: PANTHER
comment: 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128:SF66 match 1

PTHR12128
type: Resource
database: PANTHER
comment: DIHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128 match 1

PF00701
type: Resource
database: Pfam
comment: DHDPS
signature sequence match: Pfam PF00701 match 1

PIRSF001365
type: Resource
database: PIRSF
comment: DHDPS
signature sequence match: PIRSF PIRSF001365 match 1

PR00146
type: Resource
database: PRINTS
comment: DHPICSNTHASE

SM01130
type: Resource
database: SMART
comment: DHDPS
signature sequence match: SMART SM01130 match 1

TIGR00674
type: Resource
database: TIGRFAMs
comment: dapA
signature sequence match: TIGRFAMs TIGR00674 match 1

PS00665
type: Resource
database: PROSITE
comment: DHDPS_1
signature sequence match: PROSITE PS00665 match 1

PS00666
type: Resource
database: PROSITE
comment: DHDPS_2
signature sequence match: PROSITE PS00666 match 1

SIP3DCCD2FAF2A8502D
type: Structured Name
full name: 4-hydroxy-tetrahydrodipicolinate synthase
short name: HTPA synthase
ec name: 4.3.3.7

dapA
type: Gene
locus name: THEYE_A0933

SIPA550681A038742E6
type: Function Annotation
comment: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

SIP527C35B428B3C19C
type: Subunit Annotation
comment: Homotetramer; dimer of dimers.

SIPA4F512D06E2B1F98
type: Similarity Annotation
comment: Belongs to the DapA family.

SIP859630E68AF3293B
type: Caution Annotation
comment: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

PRO_1000124078
type: Chain Annotation
comment: 4-hydroxy-tetrahydrodipicolinate synthase
mass: 32118
range: 18636006094484526tt1tt291

18636006094484526tt1
type: Position
type: ExactPosition
position: 1
reference: B5YKK4-1

18636006094484526tt291
type: Position
type: ExactPosition
position: 291
reference: B5YKK4-1

SIPD3190A2F47C32F26
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18636006094484526tt132tt132

18636006094484526tt132
type: Position
type: ExactPosition
position: 132
reference: B5YKK4-1

SIPA699B6B71A5E073F
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 18636006094484526tt160tt160

18636006094484526tt160
type: Position
type: ExactPosition
position: 160
reference: B5YKK4-1

18636006094484526tt44
type: Position
type: ExactPosition
position: 44
reference: B5YKK4-1

18636006094484526tt202
type: Position
type: ExactPosition
position: 202
reference: B5YKK4-1

SIP6F4998024A7F388F
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18636006094484526tt43tt43

18636006094484526tt43
type: Position
type: ExactPosition
position: 43
reference: B5YKK4-1

SIP0D821A93D0A7971C
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18636006094484526tt106tt106

18636006094484526tt106
type: Position
type: ExactPosition
position: 106
reference: B5YKK4-1

B5YKK4-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 32118
value: MFKGSMVAIVTPFKKGKIDEKAFEKLIEWHIKEGTHGIVPCGTTGEASTLDYEEHYKVIEITVKVVNKRIPVIAGTGSNSTDEAIMITKKAEKLGADAALLVTPYYNKPTQEGLYRHYKEIADKTGIPLILYNVPGRTSVNILPQTVARLAEHPRIVGIKEATGDMKQVSELIRLCGDKITVLSGDDFTNLTLLALGGKGAISVTANICPKDMAELFNAWEKGDIEHARKLHYKLEPLNKAMFIETNPIPVKTALAMMGKIKEEFRLPLCEMSQTNKEKLAEVLRSAGLIK

http://purl.uniprot.org/uniprot/B5YKK4#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YKK4#attribution-BD5BACAA957515974E6FCCE76684BF01
manual: true
evidence: ECO_0000255
source: MF_00418

http://purl.uniprot.org/uniprot/B5YKK4#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B5YK82
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 71
mnemonic: DCUP_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP71B4CDF4EDA7ED39
enzyme: http://purl.uniprot.org/enzyme/4.1.1.37
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP21D81598125A4455
annotation: SIP88216EAB81E0F6F6
annotation: SIP2FE4ED01A343E092
annotation: SIP738042D3F4AC30E8
annotation: SIPF6413C0C583F0408
annotation: SIP3D7BB66732DDAFA9
annotation: PRO_1000100022
annotation: SIP5ADB3A544942186A
annotation: SIP2C3DFEF1895449FF
annotation: SIPC9B3212A15D11990
annotation: SIP9FC91B595648F8BD
annotation: SIPBEBA34D51E36FC58
annotation: SIP197C113C6F840B17
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/210
classified with: http://purl.uniprot.org/keywords/627
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0004853
classified with: GO_0006783
classified with: GO_0006782
sequence: B5YK82-1
proteome: Chromosome

B5YK82-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0407
type: Resource
database: eggNOG
comment: Bacteria

cd00717
type: Resource
database: CDD
comment: URO-D
signature sequence match: CDD cd00717 match 1

MF_00218
type: Resource
database: HAMAP
comment: URO_D
signature sequence match: HAMAP MF 00218 match 1

IPR038071
type: Resource
database: InterPro
comment: UROD/MetE-like_sf

IPR006361
type: Resource
database: InterPro
comment: Uroporphyrinogen_deCO2ase_HemE

IPR000257
type: Resource
database: InterPro
comment: Uroporphyrinogen_deCOase

PTHR21091
type: Resource
database: PANTHER
comment: METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED
signature sequence match: PANTHER PTHR21091 match 1

PTHR21091:SF169
type: Resource
database: PANTHER
comment: UROPORPHYRINOGEN DECARBOXYLASE
signature sequence match: PANTHER PTHR21091:SF169 match 1

PF01208
type: Resource
database: Pfam
comment: URO-D
signature sequence match: Pfam PF01208 match 1

SSF51726
type: Resource
database: SUPFAM
comment: UROD/MetE-like
signature sequence match: SUPFAM SSF51726 match 1
signature sequence match: SUPFAM SSF51726 match 2

TIGR01464
type: Resource
database: TIGRFAMs
comment: hemE
signature sequence match: TIGRFAMs TIGR01464 match 1

PS00906
type: Resource
database: PROSITE
comment: UROD_1
signature sequence match: PROSITE PS00906 match 1

PS00907
type: Resource
database: PROSITE
comment: UROD_2
signature sequence match: PROSITE PS00907 match 1

SIP71B4CDF4EDA7ED39
type: Structured Name
full name: Uroporphyrinogen decarboxylase
short name: UPD
short name: URO-D
ec name: 4.1.1.37

hemE
type: Gene
locus name: THEYE_A0806

SIP21D81598125A4455
type: Function Annotation
comment: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

SIP738042D3F4AC30E8
type: Subunit Annotation
comment: Homodimer.

SIP3D7BB66732DDAFA9
type: Similarity Annotation
comment: Belongs to the uroporphyrinogen decarboxylase family.

PRO_1000100022
type: Chain Annotation
comment: Uroporphyrinogen decarboxylase
mass: 38338
range: 18636006093238830tt1tt338

18636006093238830tt1
type: Position
type: ExactPosition
position: 1
reference: B5YK82-1

18636006093238830tt338
type: Position
type: ExactPosition
position: 338
reference: B5YK82-1

18636006093238830tt23
type: Position
type: ExactPosition
position: 23
reference: B5YK82-1

18636006093238830tt27
type: Position
type: ExactPosition
position: 27
reference: B5YK82-1

18636006093238830tt72
type: Position
type: ExactPosition
position: 72
reference: B5YK82-1

18636006093238830tt146
type: Position
type: ExactPosition
position: 146
reference: B5YK82-1

18636006093238830tt201
type: Position
type: ExactPosition
position: 201
reference: B5YK82-1

18636006093238830tt312
type: Position
type: ExactPosition
position: 312
reference: B5YK82-1

SIP197C113C6F840B17
type: Site Annotation
comment: Transition state stabilizer
range: 18636006093238830tt72tt72

substrate

B5YK82-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 38338
value: MKEAFLKACRGIRTDYTPVWFMRQAGRYMPEYQKLRQKYDFLTMCKTPEIAAEVTLQPVKVLGVDAAILFSDILIPLEAMGLKIEFIDDKGPQVLPNIRTVADLEILGELNLEKIGFVFDAIRILINELNVPLIGFAASPFTLATYVIEGGSTKEFVNTKRFMFLEPEGFHKLMSLFTKATQKYLNEQIRAGVHAVQIFDTWAGILSPFDYESFVKPYVKRLIESLKTVPVIYFSSNTAGLINHLKELNADVLSIDWRIDIKDATDLLKNKPLQGNLDPLTLLGSDEELFKRVEKVLIGARGAKSHIFNLGHGVNINTSVDKLKKLVDFVHEFKFMED

http://purl.uniprot.org/uniprot/B5YK82#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YK82#attribution-4E5E061B594E89D8C223D5E7FD64BDE5
manual: true
evidence: ECO_0000255
source: MF_00218

B5YFT1
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 85
mnemonic: DDL_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP97EEA9C6D689407F
alternative name: SIP68E9DEFDB2526EAF
alternative name: SIPB2B37D09B53E5142
enzyme: http://purl.uniprot.org/enzyme/6.3.2.4
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP293A7348E19F0A9A
annotation: SIPE215184F348A5417
annotation: SIPCD116B8F00F0A5D1
annotation: SIP32671E508BF8763D
annotation: SIPA900636391D7D2EA
annotation: SIPBEFBA543D9217FDD
annotation: PRO_1000091212
annotation: SIPEEF5F13E55129665
annotation: SIPDE8973BF81AA7C34
annotation: SIP2813A550B6D550C8
annotation: SIPAD72C3C36DF31367
annotation: SIP502FC1BCCF86E21D
annotation: SIP0F617DBEC374B813
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/961
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/573
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0008716
classified with: GO_0046872
classified with: GO_0071555
classified with: GO_0009252
classified with: GO_0008360
sequence: B5YFT1-1
proteome: Chromosome

B5YFT1-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1181
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.30.1490.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, A domain
signature sequence match: Gene3D 3.30.1490.20 match 1

http://purl.uniprot.org/gene3d/3.30.470.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, B domain
signature sequence match: Gene3D 3.30.470.20 match 1

MF_00047
type: Resource
database: HAMAP
comment: Dala_Dala_lig
signature sequence match: HAMAP MF 00047 match 1

IPR011761
type: Resource
database: InterPro
comment: ATP-grasp

IPR013815
type: Resource
database: InterPro
comment: ATP_grasp_subdomain_1

IPR000291
type: Resource
database: InterPro
comment: D-Ala_lig_Van_CS

IPR005905
type: Resource
database: InterPro
comment: D_ala_D_ala

IPR011095
type: Resource
database: InterPro
comment: Dala_Dala_lig_C

IPR011127
type: Resource
database: InterPro
comment: Dala_Dala_lig_N

IPR016185
type: Resource
database: InterPro
comment: PreATP-grasp_dom_sf

PTHR23132
type: Resource
database: PANTHER
comment: D-ALANINE--D-ALANINE LIGASE
signature sequence match: PANTHER PTHR23132 match 1

PTHR23132:SF23
type: Resource
database: PANTHER
comment: D-ALANINE--D-ALANINE LIGASE B
signature sequence match: PANTHER PTHR23132:SF23 match 1

PF07478
type: Resource
database: Pfam
comment: Dala_Dala_lig_C
signature sequence match: Pfam PF07478 match 1

PF01820
type: Resource
database: Pfam
comment: Dala_Dala_lig_N
signature sequence match: Pfam PF01820 match 1

PIRSF039102
type: Resource
database: PIRSF
comment: Ddl/VanB
signature sequence match: PIRSF PIRSF039102 match 1

SM01209
type: Resource
database: SMART
comment: GARS_A
signature sequence match: SMART SM01209 match 1

SSF56059
type: Resource
database: SUPFAM
comment: Glutathione synthetase ATP-binding domain-like
signature sequence match: SUPFAM SSF56059 match 1

SSF52440
type: Resource
database: SUPFAM
comment: PreATP-grasp domain
signature sequence match: SUPFAM SSF52440 match 1

TIGR01205
type: Resource
database: TIGRFAMs
comment: D_ala_D_alaTIGR
signature sequence match: TIGRFAMs TIGR01205 match 1

PS50975
type: Resource
database: PROSITE
comment: ATP_GRASP
signature sequence match: PROSITE PS50975 match 1

PS00843
type: Resource
database: PROSITE
comment: DALA_DALA_LIGASE_1
signature sequence match: PROSITE PS00843 match 1

PS00844
type: Resource
database: PROSITE
comment: DALA_DALA_LIGASE_2
signature sequence match: PROSITE PS00844 match 1

SIP97EEA9C6D689407F
type: Structured Name
full name: D-alanine--D-alanine ligase
ec name: 6.3.2.4

SIP68E9DEFDB2526EAF
type: Structured Name
full name: D-Ala-D-Ala ligase

SIPB2B37D09B53E5142
type: Structured Name
full name: D-alanylalanine synthetase

ddl
type: Gene
locus name: THEYE_A1319

SIP293A7348E19F0A9A
type: Function Annotation
comment: Cell wall formation.

SIPCD116B8F00F0A5D1
type: Cofactor Annotation
comment: Binds 2 magnesium or manganese ions per subunit.
cofactor: CHEBI_18420
cofactor: CHEBI_29035

SIPBEFBA543D9217FDD
type: Similarity Annotation
comment: Belongs to the D-alanine--D-alanine ligase family.

PRO_1000091212
type: Chain Annotation
comment: D-alanine--D-alanine ligase
mass: 33164
range: 18636006011187502tt1tt304

18636006011187502tt1
type: Position
type: ExactPosition
position: 1
reference: B5YFT1-1

18636006011187502tt304
type: Position
type: ExactPosition
position: 304
reference: B5YFT1-1

SIPEEF5F13E55129665
type: Domain Extent Annotation
comment: ATP-grasp
range: 18636006011187502tt99tt296

18636006011187502tt99
type: Position
type: ExactPosition
position: 99
reference: B5YFT1-1

18636006011187502tt296
type: Position
type: ExactPosition
position: 296
reference: B5YFT1-1

18636006011187502tt127
type: Position
type: ExactPosition
position: 127
reference: B5YFT1-1

18636006011187502tt182
type: Position
type: ExactPosition
position: 182
reference: B5YFT1-1

18636006011187502tt250
type: Position
type: ExactPosition
position: 250
reference: B5YFT1-1

18636006011187502tt263
type: Position
type: ExactPosition
position: 263
reference: B5YFT1-1

18636006011187502tt265
type: Position
type: ExactPosition
position: 265
reference: B5YFT1-1

1
subclass of: CHEBI_18420

2
subclass of: CHEBI_18420

B5YFT1-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 33164
value: MKVGVIAGGISSEREVSLRSGQAVFNALKELGYDVVFIDAGIDLCEKIKIEKIDIAFLVLHGGWGENGAVQGMLEVMGIPYTGSGVLASALAMDKEASKKIFLYHGIPVPPFKVLNKKDYISSAVSLSSFSFPCVVKPAEEGSSIGVNIVKNEREFKNAINEAFQFGKRVIIEKFIEGREIHIGVLGDKALGGVEVRPKKGFYSYEAKYTKGLTEYILPPEIDNALYEKLKELGLKAHKSLNCKGGTRVDMIVDQQGNPYVLEVNTIPGMTETSLLPKIASLAGYDFKGLVKEILELSLKNNEK

http://purl.uniprot.org/uniprot/B5YFT1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YFT1#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/B5YFT1#attribution-A0A5C738C775730E0CCEA3AE6FA50A40
manual: true
evidence: ECO_0000255
source: MF_00047

B5YIL7
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 74
mnemonic: DEF_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP4DBF63A64CA12CE0
alternative name: SIPFCC85FB4173C1EC9
enzyme: http://purl.uniprot.org/enzyme/3.5.1.88
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP871B4D9C568BE624
annotation: SIPDD984E33537353F1
annotation: SIP89AAE20DFBF35E0D
annotation: SIP46A585A96565E4B4
annotation: PRO_1000097356
annotation: SIP27679035A90AA6B7
annotation: SIP6D0D6E5BE0199EF9
annotation: SIP499B97FDC27D0AE1
annotation: SIPF28A9DA691D10454
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/408
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0046872
classified with: GO_0042586
classified with: GO_0043686
classified with: GO_0031365
classified with: GO_0018206
classified with: GO_0006412
sequence: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK
proteome: Chromosome

B5YIL7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0242
type: Resource
database: eggNOG
comment: Bacteria

cd00487
type: Resource
database: CDD
comment: Pep_deformylase
signature sequence match: CDD cd00487 match 1

http://purl.uniprot.org/gene3d/3.90.45.10
type: Resource
database: Gene3D
comment: Peptide deformylase
signature sequence match: Gene3D 3.90.45.10 match 1

MF_00163
type: Resource
database: HAMAP
comment: Pep_deformylase
signature sequence match: HAMAP MF 00163 match 1

IPR023635
type: Resource
database: InterPro
comment: Peptide_deformylase

IPR036821
type: Resource
database: InterPro
comment: Peptide_deformylase_sf

PTHR10458
type: Resource
database: PANTHER
comment: PEPTIDE DEFORMYLASE
signature sequence match: PANTHER PTHR10458 match 1

PTHR10458:SF22
type: Resource
database: PANTHER
comment: PEPTIDE DEFORMYLASE
signature sequence match: PANTHER PTHR10458:SF22 match 1

PF01327
type: Resource
database: Pfam
comment: Pep_deformylase
signature sequence match: Pfam PF01327 match 1

PIRSF004749
type: Resource
database: PIRSF
comment: Pep_def
signature sequence match: PIRSF PIRSF004749 match 1

PR01576
type: Resource
database: PRINTS
comment: PDEFORMYLASE

SSF56420
type: Resource
database: SUPFAM
comment: Peptide deformylase
signature sequence match: SUPFAM SSF56420 match 1

TIGR00079
type: Resource
database: TIGRFAMs
comment: pept_deformyl
signature sequence match: TIGRFAMs TIGR00079 match 1

SIP4DBF63A64CA12CE0
type: Structured Name
full name: Peptide deformylase
short name: PDF
ec name: 3.5.1.88

SIPFCC85FB4173C1EC9
type: Structured Name
full name: Polypeptide deformylase

def
type: Gene
locus name: THEYE_A0329

SIP871B4D9C568BE624
type: Function Annotation
comment: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

SIP89AAE20DFBF35E0D
type: Cofactor Annotation
comment: Binds 1 Fe(2+) ion.
cofactor: CHEBI_29033

SIP46A585A96565E4B4
type: Similarity Annotation
comment: Belongs to the polypeptide deformylase family.

PRO_1000097356
type: Chain Annotation
comment: Peptide deformylase
mass: 18570
range: 18636006060996398tt1tt165

18636006060996398tt1
type: Position
type: ExactPosition
position: 1
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

18636006060996398tt165
type: Position
type: ExactPosition
position: 165
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

18636006060996398tt136
type: Position
type: ExactPosition
position: 136
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

18636006060996398tt93
type: Position
type: ExactPosition
position: 93
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

18636006060996398tt135
type: Position
type: ExactPosition
position: 135
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

18636006060996398tt139
type: Position
type: ExactPosition
position: 139
reference: MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK

MAILEIKKYPDEVLKKKAETISEINGDLQKLIDNMIETMYNANGIGLAAPQVGVLKRLIVVDTSPREQNQSLIVLINPEITDSEGEILSEEGCLSLPGFTTRLKRKERVIVKGLDRNGKEIEIEATGLLARALQHEIDHLDGILLIDKISPLKRELFRKKFKTKK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 18570

http://purl.uniprot.org/uniprot/B5YIL7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YIL7#attribution-C2600E8E092EA4975A3CC32A86C7B414
manual: true
evidence: ECO_0000255
source: MF_00163

B5YFX9
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 75
mnemonic: DER_THEYD
old mnemonic: ENGA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP2330F71CA8A314DB
alternative name: SIP12F40DC05E2E52C8
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP3DAD19C40C2718FC
annotation: SIPAA25006C60EFCEDB
annotation: SIPF370D9FFC6959BDF
annotation: PRO_1000099175
annotation: SIP896F8268FC9035D5
annotation: SIPAF39BA7512B4DCE1
annotation: SIPC8F3816058254AFB
annotation: SIP4F62F49CBA078FD0
annotation: SIP3C6D7DD82FBCE232
annotation: SIPC46077C13179E71C
annotation: SIP498BBEFC84CD9853
annotation: SIP2E450925100DB613
annotation: SIP23611C1B31B2FE96
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/690
classified with: GO_0005525
classified with: GO_0043022
classified with: GO_0000027
sequence: B5YFX9-1
proteome: Chromosome

B5YFX9-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1160
type: Resource
database: eggNOG
comment: Bacteria

cd01894
type: Resource
database: CDD
comment: EngA1
signature sequence match: CDD cd01894 match 1

cd01895
type: Resource
database: CDD
comment: EngA2
signature sequence match: CDD cd01895 match 1

MF_00195
type: Resource
database: HAMAP
comment: GTPase_Der
signature sequence match: HAMAP MF 00195 match 1

IPR031166
type: Resource
database: InterPro
comment: G_ENGA

IPR006073
type: Resource
database: InterPro
comment: GTP-bd

IPR016484
type: Resource
database: InterPro
comment: GTP-bd_EngA

IPR032859
type: Resource
database: InterPro
comment: KH_dom-like

IPR015946
type: Resource
database: InterPro
comment: KH_dom-like_a/b

IPR005225
type: Resource
database: InterPro
comment: Small_GTP-bd_dom

PTHR43834:SF6
type: Resource
database: PANTHER
comment: GTP-BINDING PROTEIN ENGA
signature sequence match: PANTHER PTHR43834:SF6 match 1

PTHR43834
type: Resource
database: PANTHER
comment: GTPASE DER
signature sequence match: PANTHER PTHR43834 match 1

PF14714
type: Resource
database: Pfam
comment: KH_dom-like
signature sequence match: Pfam PF14714 match 1

PF01926
type: Resource
database: Pfam
comment: MMR_HSR1
signature sequence match: Pfam PF01926 match 1
signature sequence match: Pfam PF01926 match 2

PIRSF006485
type: Resource
database: PIRSF
comment: GTP-binding_EngA
signature sequence match: PIRSF PIRSF006485 match 1

PR00326
type: Resource
database: PRINTS
comment: GTP1OBG

TIGR03594
type: Resource
database: TIGRFAMs
comment: GTPase_EngA
signature sequence match: TIGRFAMs TIGR03594 match 1

TIGR00231
type: Resource
database: TIGRFAMs
comment: small_GTP
signature sequence match: TIGRFAMs TIGR00231 match 1
signature sequence match: TIGRFAMs TIGR00231 match 2

PS51712
type: Resource
database: PROSITE
comment: G_ENGA
signature sequence match: PROSITE PS51712 match 1
signature sequence match: PROSITE PS51712 match 2

SIP2330F71CA8A314DB
type: Structured Name
full name: GTPase Der

SIP12F40DC05E2E52C8
type: Structured Name
full name: GTP-binding protein EngA

der
type: Gene
alternative label: engA
locus name: THEYE_A1376

SIP3DAD19C40C2718FC
type: Function Annotation
comment: GTPase that plays an essential role in the late steps of ribosome biogenesis.

SIPAA25006C60EFCEDB
type: Subunit Annotation
comment: Associates with the 50S ribosomal subunit.

SIPF370D9FFC6959BDF
type: Similarity Annotation
comment: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

PRO_1000099175
type: Chain Annotation
comment: GTPase Der
mass: 51363
range: 18636006011451694tt1tt448

18636006011451694tt1
type: Position
type: ExactPosition
position: 1
reference: B5YFX9-1

18636006011451694tt448
type: Position
type: ExactPosition
position: 448
reference: B5YFX9-1

SIP896F8268FC9035D5
type: Domain Extent Annotation
comment: EngA-type G 1
range: 18636006011451694tt2tt171

18636006011451694tt2
type: Position
type: ExactPosition
position: 2
reference: B5YFX9-1

18636006011451694tt171
type: Position
type: ExactPosition
position: 171
reference: B5YFX9-1

SIPAF39BA7512B4DCE1
type: Domain Extent Annotation
comment: EngA-type G 2
range: 18636006011451694tt181tt364

18636006011451694tt181
type: Position
type: ExactPosition
position: 181
reference: B5YFX9-1

18636006011451694tt364
type: Position
type: ExactPosition
position: 364
reference: B5YFX9-1

SIPC8F3816058254AFB
type: Domain Extent Annotation
comment: KH-like
range: 18636006011451694tt365tt448

18636006011451694tt365
type: Position
type: ExactPosition
position: 365
reference: B5YFX9-1

18636006011451694tt8
type: Position
type: ExactPosition
position: 8
reference: B5YFX9-1

18636006011451694tt15
type: Position
type: ExactPosition
position: 15
reference: B5YFX9-1

18636006011451694tt58
type: Position
type: ExactPosition
position: 58
reference: B5YFX9-1

18636006011451694tt62
type: Position
type: ExactPosition
position: 62
reference: B5YFX9-1

18636006011451694tt123
type: Position
type: ExactPosition
position: 123
reference: B5YFX9-1

18636006011451694tt126
type: Position
type: ExactPosition
position: 126
reference: B5YFX9-1

18636006011451694tt187
type: Position
type: ExactPosition
position: 187
reference: B5YFX9-1

18636006011451694tt194
type: Position
type: ExactPosition
position: 194
reference: B5YFX9-1

18636006011451694tt234
type: Position
type: ExactPosition
position: 234
reference: B5YFX9-1

18636006011451694tt238
type: Position
type: ExactPosition
position: 238
reference: B5YFX9-1

18636006011451694tt305
type: Position
type: ExactPosition
position: 305
reference: B5YFX9-1

18636006011451694tt308
type: Position
type: ExactPosition
position: 308
reference: B5YFX9-1

1
subclass of: CHEBI_37565

2
subclass of: CHEBI_37565

B5YFX9-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 51363
value: MFTVVIVGRPNVGKSTLFNRMIKSDEKIKAITDKFPGVTRDINYGVAKWDDKEFIVVDTGGFFPEEKIEDIIQKQMLEQIEMAISDADLIIHLLDSKEGLLPDDIETARQLRQTGKDILWVVNKIDDPSKLSRIYDFYSIGTEELIPISGITGYGFDELIDKIIEKIPDTQPVNLEQQNLPKIAVVGRPNVGKSTIINALLGKKRMIVSPIPGTTRDTIDAICTYYGKKYLLIDTAGIKRLSYYKKEISQEIYVERLAYFKALRSIERADVAILVIDALEGIVNQDQKIAGIVAEQKKGLIILINKWDLIPANERDKKAKFFTDEIKHKLWFVDYAPYLTVSAIDKTRLTKIFPLIDQILEEYSKRVSTSELNRLFSEKLKDVIMSSHGKELKFYYITQVNVAPPTFVVFVNDQSAVKQHHIKFIEKLLRETFHFKFSPINIKIKQRK

http://purl.uniprot.org/uniprot/B5YFX9#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YFX9#attribution-3BD876A211ED32AF99CF0E5E3E1B3BEC
manual: true
evidence: ECO_0000255
source: MF_00195

B5YJG7
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 67
mnemonic: DGTL1_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP74A4099EA6547AB3
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP4B209144C62F126E
annotation: PRO_1000138937
annotation: SIPF43B1A88126148F4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0008832
classified with: GO_0006203
sequence: B5YJG7-1
proteome: Chromosome

B5YJG7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0232
type: Resource
database: eggNOG
comment: Bacteria

cd00077
type: Resource
database: CDD
comment: HDc
signature sequence match: CDD cd00077 match 1

http://purl.uniprot.org/gene3d/1.10.3210.10
type: Resource
database: Gene3D
comment: Hypothetical protein af1432
signature sequence match: Gene3D 1.10.3210.10 match 1

MF_01212
type: Resource
database: HAMAP
comment: dGTPase_type2
signature sequence match: HAMAP MF 01212 match 1

IPR006261
type: Resource
database: InterPro
comment: dNTPase

IPR023023
type: Resource
database: InterPro
comment: dNTPase_2

IPR003607
type: Resource
database: InterPro
comment: HD/PDEase_dom

IPR006674
type: Resource
database: InterPro
comment: HD_domain

IPR026875
type: Resource
database: InterPro
comment: PHydrolase_assoc_dom

PTHR35795
type: Resource
database: PANTHER
comment: SLR1885 PROTEIN
signature sequence match: PANTHER PTHR35795 match 1

PTHR35795:SF1
type: Resource
database: PANTHER
comment: SLR1885 PROTEIN
signature sequence match: PANTHER PTHR35795:SF1 match 1

PF01966
type: Resource
database: Pfam
comment: HD
signature sequence match: Pfam PF01966 match 1

PF13286
type: Resource
database: Pfam
comment: HD_assoc
signature sequence match: Pfam PF13286 match 1

SM00471
type: Resource
database: SMART
comment: HDc
signature sequence match: SMART SM00471 match 1

SSF109604
type: Resource
database: SUPFAM
comment: HD-domain/PDEase-like
signature sequence match: SUPFAM SSF109604 match 1

TIGR01353
type: Resource
database: TIGRFAMs
comment: dGTP_triPase
signature sequence match: TIGRFAMs TIGR01353 match 1

PS51831
type: Resource
database: PROSITE
comment: HD
signature sequence match: PROSITE PS51831 match 1

SIP74A4099EA6547AB3
type: Structured Name
full name: Deoxyguanosinetriphosphate triphosphohydrolase-like protein

http://purl.uniprot.org/uniprot/B5YJG7#gene-MD5710BDA61BD01C52C8750EA78B7E2F322
type: Gene
locus name: THEYE_A0539

SIP4B209144C62F126E
type: Similarity Annotation
comment: Belongs to the dGTPase family. Type 2 subfamily.

PRO_1000138937
type: Chain Annotation
comment: Deoxyguanosinetriphosphate triphosphohydrolase-like protein
mass: 39923
range: 18636006077445934tt1tt339

18636006077445934tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJG7-1

18636006077445934tt339
type: Position
type: ExactPosition
position: 339
reference: B5YJG7-1

SIPF43B1A88126148F4
type: Domain Extent Annotation
comment: HD
range: 18636006077445934tt75tt192

18636006077445934tt75
type: Position
type: ExactPosition
position: 75
reference: B5YJG7-1

18636006077445934tt192
type: Position
type: ExactPosition
position: 192
reference: B5YJG7-1

B5YJG7-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 39923
value: MNIRERYQEIEKSFLHPKSCLSSQTKGRLKPEPEDDIRTPFQRDRDRIIHSKAFRRLKHKTQVFFSPQGDHYRTRLTHVFEVSQISRTIARALRLNEDLTEAIALGHDLGHTPFGHAGEAILRELHPGGFEHYEQSLRVVDILEKNGKGLNLTFEVRDGILKHSKGRGKILSDEPFTLEGQIVRVGDVIAYINHDIDDAIRAGIIKKNDIPQQFLKFFGDRHSKRIDKMVRDVIFTTIKEDYEKISMSPEMEEMVHSFRDFLFEKVYYNERIIEEFKKAKRMLESLYNYYLDNPHIIDAQELEEKELHRKICDFIAGMTDRYALYTFEKIFIPKSWAVP

http://purl.uniprot.org/uniprot/B5YJG7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJG7#attribution-2D92BBDF2BB0C8D0BC8C884CE6A5B047
manual: true
evidence: ECO_0000255
source: MF_01212

http://purl.uniprot.org/uniprot/B5YJG7#attribution-7F0A0D957167C8E65A730A530587D3A9
manual: true
evidence: ECO_0000255
source: PRU01175

B5YGT9
type: Protein
reviewed: true
created: 2009-09-22
modified: 2023-05-03
version: 82
mnemonic: DNAA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPCBCFC2E9BA151A7C
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP39B4BA4EC65B92F6
annotation: SIP8FCDE955BDDB0696
annotation: SIP34978D82ABFEF1D7
annotation: PRO_1000205665
annotation: SIP4B4513B5E01A0778
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005886
classified with: GO_0005524
classified with: GO_0003688
classified with: GO_0006260
classified with: GO_0006270
classified with: GO_0006275
sequence: B5YGT9-1
proteome: Chromosome

B5YGT9-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0593
type: Resource
database: eggNOG
comment: Bacteria

cd00009
type: Resource
database: CDD
comment: AAA
signature sequence match: CDD cd00009 match 1

cd06571
type: Resource
database: CDD
comment: Bac_DnaA_C
signature sequence match: CDD cd06571 match 1

MF_00377
type: Resource
database: HAMAP
comment: DnaA_bact
signature sequence match: HAMAP MF 00377 match 1

IPR001957
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA

IPR020591
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA-like

IPR018312
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA_CS

IPR013317
type: Resource
database: InterPro
comment: DnaA

IPR013159
type: Resource
database: InterPro
comment: DnaA_C

IPR024633
type: Resource
database: InterPro
comment: DnaA_N_dom

IPR038454
type: Resource
database: InterPro
comment: DnaA_N_sf

IPR010921
type: Resource
database: InterPro
comment: Trp_repressor/repl_initiator

PTHR30050
type: Resource
database: PANTHER
comment: CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA
signature sequence match: PANTHER PTHR30050 match 1

PTHR30050:SF2
type: Resource
database: PANTHER
comment: CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA
signature sequence match: PANTHER PTHR30050:SF2 match 1

PF00308
type: Resource
database: Pfam
comment: Bac_DnaA
signature sequence match: Pfam PF00308 match 1

PF08299
type: Resource
database: Pfam
comment: Bac_DnaA_C
signature sequence match: Pfam PF08299 match 1

PF11638
type: Resource
database: Pfam
comment: DnaA_N
signature sequence match: Pfam PF11638 match 1

PR00051
type: Resource
database: PRINTS
comment: DNAA

SM00760
type: Resource
database: SMART
comment: Bac_DnaA_C
signature sequence match: SMART SM00760 match 1

SSF48295
type: Resource
database: SUPFAM
comment: TrpR-like
signature sequence match: SUPFAM SSF48295 match 1

TIGR00362
type: Resource
database: TIGRFAMs
comment: DnaA
signature sequence match: TIGRFAMs TIGR00362 match 1

PS01008
type: Resource
database: PROSITE
comment: DNAA
signature sequence match: PROSITE PS01008 match 1

SIPCBCFC2E9BA151A7C
type: Structured Name
full name: Chromosomal replication initiator protein DnaA

dnaA
type: Gene
locus name: THEYE_A0015

SIP39B4BA4EC65B92F6
type: Function Annotation
comment: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

SIP34978D82ABFEF1D7
type: Similarity Annotation
comment: Belongs to the DnaA family.

PRO_1000205665
type: Chain Annotation
comment: Chromosomal replication initiator protein DnaA
mass: 49900
range: 18636006027966766tt1tt438

18636006027966766tt1
type: Position
type: ExactPosition
position: 1
reference: B5YGT9-1

18636006027966766tt438
type: Position
type: ExactPosition
position: 438
reference: B5YGT9-1

18636006027966766tt142
type: Position
type: ExactPosition
position: 142
reference: B5YGT9-1

18636006027966766tt149
type: Position
type: ExactPosition
position: 149
reference: B5YGT9-1

B5YGT9-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 49900
value: MNEINKIWQKILEIILEKVGESTFELWFSPIKLLDIKNSEAFIEVPNRFFKDWIEDNFPSIISDSFYQITGSQVEVKYIITGKEHETGLIEEKKQVIKKGNLNPKYTFDTFVVGPSNQFAHAASFRVAENPGFAYNPLFIYGGVGLGKTHLITAIGNYILDKKPEMNVCYISSEQFTGEFVSAIRHEKMPEFRNKYRTVDVFLVDDIQFIAGKDSTQEEFFHTFNELYSKQKQIVISSDRPPMEISDITDRLRSRFGMGLIADIQPPEIETRLAILYKKADMEGVKLPEDVAYFIASRVKSNVRELEGSLIKLCAYTSLTKVPISMDVAKYVLRDLLPDENKPITIELIQKAVCEAVGLKIQDIKSKKRTKEISNARKLAMYITKKLTNLSLAEIGNAFGGKDHATVIYACKQVEKEKEKDESISRLIDSIIKKVTGQ

http://purl.uniprot.org/uniprot/B5YGT9#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YGT9#attribution-DBF1A02807F1BF3B2D49375A3DDDD731
manual: true
evidence: ECO_0000255
source: MF_00377

B5YH59
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 78
mnemonic: DNAK_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP77347BD26C11F2DD
alternative name: SIPB9F2AC767B62F30E
alternative name: SIP46A93DADC713DCB9
alternative name: SIPE022D25B133FC824
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP8A65D87A9F54D6C2
annotation: SIP7FC1784A3B1BA599
annotation: SIP269C1EBB5B91C494
annotation: PRO_1000119770
annotation: SIPD33EE1062A100BE9
annotation: SIP2E4393208746FC07
annotation: SIP6823A336C97654C2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/346
classified with: GO_0005829
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0031072
classified with: GO_0044183
classified with: GO_0051082
classified with: GO_0051085
classified with: GO_0042026
sequence: B5YH59-1
proteome: Chromosome

B5YH59-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0443
type: Resource
database: eggNOG
comment: Bacteria

cd10234
type: Resource
database: CDD
comment: HSPA9-Ssq1-like_NBD
signature sequence match: CDD cd10234 match 1

MF_00332
type: Resource
database: HAMAP
comment: DnaK
signature sequence match: HAMAP MF 00332 match 1

IPR043129
type: Resource
database: InterPro
comment: ATPase_NBD

IPR012725
type: Resource
database: InterPro
comment: Chaperone_DnaK

IPR018181
type: Resource
database: InterPro
comment: Heat_shock_70_CS

IPR029048
type: Resource
database: InterPro
comment: HSP70_C_sf

IPR029047
type: Resource
database: InterPro
comment: HSP70_peptide-bd_sf

IPR013126
type: Resource
database: InterPro
comment: Hsp_70_fam

PTHR19375
type: Resource
database: PANTHER
comment: HEAT SHOCK PROTEIN 70KDA
signature sequence match: PANTHER PTHR19375 match 1

PTHR19375:SF184
type: Resource
database: PANTHER
comment: STRESS-70 PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR19375:SF184 match 1

PF00012
type: Resource
database: Pfam
comment: HSP70
signature sequence match: Pfam PF00012 match 1

PR00301
type: Resource
database: PRINTS
comment: HEATSHOCK70

SSF53067
type: Resource
database: SUPFAM
comment: Actin-like ATPase domain
signature sequence match: SUPFAM SSF53067 match 1
signature sequence match: SUPFAM SSF53067 match 2

SSF100934
type: Resource
database: SUPFAM
comment: Heat shock protein 70kD (HSP70), C-terminal subdomain
signature sequence match: SUPFAM SSF100934 match 1

SSF100920
type: Resource
database: SUPFAM
comment: Heat shock protein 70kD (HSP70), peptide-binding domain
signature sequence match: SUPFAM SSF100920 match 1

TIGR02350
type: Resource
database: TIGRFAMs
comment: prok_dnaK
signature sequence match: TIGRFAMs TIGR02350 match 1

PS00297
type: Resource
database: PROSITE
comment: HSP70_1
signature sequence match: PROSITE PS00297 match 1

PS00329
type: Resource
database: PROSITE
comment: HSP70_2
signature sequence match: PROSITE PS00329 match 1

SIP77347BD26C11F2DD
type: Structured Name
full name: Chaperone protein DnaK

SIPB9F2AC767B62F30E
type: Structured Name
full name: HSP70

SIP46A93DADC713DCB9
type: Structured Name
full name: Heat shock 70 kDa protein

SIPE022D25B133FC824
type: Structured Name
full name: Heat shock protein 70

dnaK
type: Gene
locus name: THEYE_A1758

SIP8A65D87A9F54D6C2
type: Function Annotation
comment: Acts as a chaperone.

SIP7FC1784A3B1BA599
type: Induction Annotation
comment: By stress conditions e.g. heat shock.

SIP269C1EBB5B91C494
type: Similarity Annotation
comment: Belongs to the heat shock protein 70 family.

PRO_1000119770
type: Chain Annotation
comment: Chaperone protein DnaK
mass: 69290
range: 18636006042712366tt1tt632

18636006042712366tt1
type: Position
type: ExactPosition
position: 1
reference: B5YH59-1

18636006042712366tt632
type: Position
type: ExactPosition
position: 632
reference: B5YH59-1

SIPD33EE1062A100BE9
type: Region Annotation
comment: Disordered
range: 18636006042712366tt599tt632

18636006042712366tt599
type: Position
type: ExactPosition
position: 599
reference: B5YH59-1

SIP2E4393208746FC07
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18636006042712366tt616tt632

18636006042712366tt616
type: Position
type: ExactPosition
position: 616
reference: B5YH59-1

SIP6823A336C97654C2
type: Modified Residue Annotation
comment: Phosphothreonine; by autocatalysis
range: 18636006042712366tt198tt198

18636006042712366tt198
type: Position
type: ExactPosition
position: 198
reference: B5YH59-1

B5YH59-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 69290
value: MGKAIGIDLGTTNSVVAVVVGGEPVVIPNQEGQRTTPSVVAFTDKGERLVGQVAKRQAITNPENTIFSIKRLMGRKYNSQEVQEAKKRLPYKIVEAPNGDAHVEIMGKRYSPPEISAMILQKLKQAAEDYLGEPVTEAVITVPAYFDDSQRQATKDAGRIAGLNVLRIINEPTAAALAYGLDKKKEEKIAVYDLGGGTFDISILEIGEGVIEVKATNGDTYLGGDDFDIRVMDWLIEEFKKQEGIDLRKDRMALQRLKEAAERAKIELSSAMETEINLPFITADASGPKHLLMKLTRAKLEQLVDDLIQKSLEPCKKALSDAGLSQSQIDEVILVGGQTRTPKVQKVVQDFFGKEPHKGVNPDEVVAVGAAIQAAILKGEVKEVLLLDVTPLSLGIETLGGVFTKIIERNTTIPTKKSQIFTTAADNQTAVTIKVYQGEREMAADNKLLGVFELVGIPPAPRGIPQIEVTFDIDANGILHVSAKDLATGKEQSIRITASSGLSEEEIKKMIREAEAHAEEDRRKKQIAEARNEADNMIYTVEKTLRDMGDRISEDERKRIEEAIEKCRRIKDTSNDVNEIKAAVEELAKASHRVAEELYKKAGASQQGAGSTTQSKKEEDVIEAEVEDKDNK

http://purl.uniprot.org/uniprot/B5YH59#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YH59#attribution-DF48ACB5BC6928786EC8A207943949A8
manual: true
evidence: ECO_0000255
source: MF_00332

B5YIF8
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 82
mnemonic: DNLJ_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP61544389502FCBE3
alternative name: SIPBF6E3D52175D0838
enzyme: http://purl.uniprot.org/enzyme/6.5.1.2
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP1C69C2943DEBE138
annotation: SIP894736C0ECAE07E1
annotation: SIPE983B56DC3EBE46C
annotation: SIPB19A574DF6E120CC
annotation: PRO_0000380498
annotation: SIP5559EAD266187DBF
annotation: SIP1C59A6B09F4F1CF5
annotation: SIP0041E246A3CB0424
annotation: SIP253F87C6FF25C253
annotation: SIPF4675C85CD3D45C4
annotation: SIP5A98FABE05C1BF8B
annotation: SIP3186F2792E004C40
annotation: SIPAC7E19E5763E907E
annotation: SIP10E2E50D2CE2C320
annotation: SIP521803EA3D832271
annotation: SIPB2044BB617A8B15F
annotation: SIPFF94036920D375AB
annotation: SIP9F0BC014D366DB92
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005829
classified with: GO_0003677
classified with: GO_0003911
classified with: GO_0046872
classified with: GO_0006288
classified with: GO_0006260
sequence: B5YIF8-1
proteome: Chromosome

B5YIF8-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0272
type: Resource
database: eggNOG
comment: Bacteria

cd17748
type: Resource
database: CDD
comment: BRCT_DNA_ligase_like
signature sequence match: CDD cd17748 match 1

cd00114
type: Resource
database: CDD
comment: LIGANc
signature sequence match: CDD cd00114 match 1

http://purl.uniprot.org/gene3d/1.10.150.20
type: Resource
database: Gene3D
comment: 5' to 3' exonuclease, C-terminal subdomain
signature sequence match: Gene3D 1.10.150.20 match 1
signature sequence match: Gene3D 1.10.150.20 match 2

http://purl.uniprot.org/gene3d/3.40.50.10190
type: Resource
database: Gene3D
comment: BRCT domain
signature sequence match: Gene3D 3.40.50.10190 match 1

http://purl.uniprot.org/gene3d/3.30.470.30
type: Resource
database: Gene3D
comment: DNA ligase/mRNA capping enzyme
signature sequence match: Gene3D 3.30.470.30 match 1

http://purl.uniprot.org/gene3d/1.10.287.610
type: Resource
database: Gene3D
comment: Helix hairpin bin
signature sequence match: Gene3D 1.10.287.610 match 1

http://purl.uniprot.org/gene3d/2.40.50.140
type: Resource
database: Gene3D
comment: Nucleic acid-binding proteins
signature sequence match: Gene3D 2.40.50.140 match 1
signature sequence match: Gene3D 2.40.50.140 match 2

MF_01588
type: Resource
database: HAMAP
comment: DNA_ligase_A
signature sequence match: HAMAP MF 01588 match 1

IPR001357
type: Resource
database: InterPro
comment: BRCT_dom

IPR036420
type: Resource
database: InterPro
comment: BRCT_dom_sf

IPR041663
type: Resource
database: InterPro
comment: DisA/LigA_HHH

IPR033136
type: Resource
database: InterPro
comment: DNA_ligase_CS

IPR001679
type: Resource
database: InterPro
comment: DNAligase

IPR013839
type: Resource
database: InterPro
comment: DNAligase_adenylation

IPR013840
type: Resource
database: InterPro
comment: DNAligase_N

IPR003583
type: Resource
database: InterPro
comment: Hlx-hairpin-Hlx_DNA-bd_motif

IPR012340
type: Resource
database: InterPro
comment: NA-bd_OB-fold

IPR004150
type: Resource
database: InterPro
comment: NAD_DNA_ligase_OB

IPR010994
type: Resource
database: InterPro
comment: RuvA_2-like

IPR004149
type: Resource
database: InterPro
comment: Znf_DNAligase_C4

PTHR23389
type: Resource
database: PANTHER
comment: CHROMOSOME TRANSMISSION FIDELITY FACTOR 18
signature sequence match: PANTHER PTHR23389 match 1

PTHR23389:SF9
type: Resource
database: PANTHER
comment: DNA LIGASE
signature sequence match: PANTHER PTHR23389:SF9 match 1

PF00533
type: Resource
database: Pfam
comment: BRCT
signature sequence match: Pfam PF00533 match 1

PF01653
type: Resource
database: Pfam
comment: DNA_ligase_aden
signature sequence match: Pfam PF01653 match 1

PF03120
type: Resource
database: Pfam
comment: DNA_ligase_OB
signature sequence match: Pfam PF03120 match 1

PF03119
type: Resource
database: Pfam
comment: DNA_ligase_ZBD
signature sequence match: Pfam PF03119 match 1

PF12826
type: Resource
database: Pfam
comment: HHH_2
signature sequence match: Pfam PF12826 match 1

PIRSF001604
type: Resource
database: PIRSF
comment: LigA
signature sequence match: PIRSF PIRSF001604 match 1

SM00292
type: Resource
database: SMART
comment: BRCT
signature sequence match: SMART SM00292 match 1

SM00278
type: Resource
database: SMART
comment: HhH1
signature sequence match: SMART SM00278 match 1
signature sequence match: SMART SM00278 match 2
signature sequence match: SMART SM00278 match 3

SM00532
type: Resource
database: SMART
comment: LIGANc
signature sequence match: SMART SM00532 match 1

SSF52113
type: Resource
database: SUPFAM
comment: BRCT domain
signature sequence match: SUPFAM SSF52113 match 1

SSF56091
type: Resource
database: SUPFAM
comment: DNA ligase/mRNA capping enzyme, catalytic domain
signature sequence match: SUPFAM SSF56091 match 1

SSF50249
type: Resource
database: SUPFAM
comment: Nucleic acid-binding proteins
signature sequence match: SUPFAM SSF50249 match 1
signature sequence match: SUPFAM SSF50249 match 2

SSF47781
type: Resource
database: SUPFAM
comment: RuvA domain 2-like
signature sequence match: SUPFAM SSF47781 match 1

TIGR00575
type: Resource
database: TIGRFAMs
comment: dnlj
signature sequence match: TIGRFAMs TIGR00575 match 1

PS50172
type: Resource
database: PROSITE
comment: BRCT
signature sequence match: PROSITE PS50172 match 1

PS01056
type: Resource
database: PROSITE
comment: DNA_LIGASE_N2
signature sequence match: PROSITE PS01056 match 1

SIP61544389502FCBE3
type: Structured Name
full name: DNA ligase
ec name: 6.5.1.2

SIPBF6E3D52175D0838
type: Structured Name
full name: Polydeoxyribonucleotide synthase [NAD(+)]

ligA
type: Gene
locus name: THEYE_A2000

SIP1C69C2943DEBE138
type: Function Annotation
comment: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

SIPB19A574DF6E120CC
type: Similarity Annotation
comment: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.

PRO_0000380498
type: Chain Annotation
comment: DNA ligase
mass: 76155
range: 18636006060603438tt1tt670

18636006060603438tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIF8-1

18636006060603438tt670
type: Position
type: ExactPosition
position: 670
reference: B5YIF8-1

SIP5559EAD266187DBF
type: Domain Extent Annotation
comment: BRCT
range: 18636006060603438tt594tt670

18636006060603438tt594
type: Position
type: ExactPosition
position: 594
reference: B5YIF8-1

SIP1C59A6B09F4F1CF5
type: Active Site Annotation
comment: N6-AMP-lysine intermediate
range: 18636006060603438tt118tt118

18636006060603438tt118
type: Position
type: ExactPosition
position: 118
reference: B5YIF8-1

18636006060603438tt36
type: Position
type: ExactPosition
position: 36
reference: B5YIF8-1

18636006060603438tt40
type: Position
type: ExactPosition
position: 40
reference: B5YIF8-1

18636006060603438tt84
type: Position
type: ExactPosition
position: 84
reference: B5YIF8-1

18636006060603438tt85
type: Position
type: ExactPosition
position: 85
reference: B5YIF8-1

18636006060603438tt116
type: Position
type: ExactPosition
position: 116
reference: B5YIF8-1

18636006060603438tt139
type: Position
type: ExactPosition
position: 139
reference: B5YIF8-1

18636006060603438tt177
type: Position
type: ExactPosition
position: 177
reference: B5YIF8-1

18636006060603438tt293
type: Position
type: ExactPosition
position: 293
reference: B5YIF8-1

18636006060603438tt317
type: Position
type: ExactPosition
position: 317
reference: B5YIF8-1

18636006060603438tt411
type: Position
type: ExactPosition
position: 411
reference: B5YIF8-1

18636006060603438tt414
type: Position
type: ExactPosition
position: 414
reference: B5YIF8-1

18636006060603438tt429
type: Position
type: ExactPosition
position: 429
reference: B5YIF8-1

18636006060603438tt434
type: Position
type: ExactPosition
position: 434
reference: B5YIF8-1

B5YIF8-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 76155
value: MKQIPEDIKKEIEKLVKELNYHNYRYYVLDSPVISDEEYDMMLRRLKELEEKWGYILPDSPTQRVGAAPSEKFEKAEHREPMLSLDNAFSIEELRDFDARVKRLLGSSEEVEYTVEPKYDGLAVELSYKDGLLYKASTRGDGYVGEDITQNIKTIKAIPLRIEGVDKIPEEIDIRGEVYLNIDEFERINKERIEKGEPVFANPRNAASGSVRQLDPSITASRRLYMSCYGIGYVKGIEFKSQIEFIEWLKKGRFPVPAYVKLAKGIEEVIEAIKEIEKLRQGYPFETDGAVVKVNSFELQRKLGTKTREPRWAIAYKYPAHQGITKLKDILASVGRTGVITPVAVLEPVKIGGVTVSRSTLHNWDEVERKDIRVGDYVIVERAGEVIPHIIGVVKDRRTGEEKEVKIPEHCPVCGSKTVREPGEVAVKCINFNCPAQVEERIKHFASRRAMNIEGLGDKTVELLHNKGIIKHFVDLYKLRQEDIKGLPGFAELSSKKLIEAIAKSKKTTLSRLLYALGISQVGEYASKLLAQHFRKLEDLYHIKAEKLVQIPQIGEKTAKTIEQFFNNEENLKAIEELKRMGLKVENPEFEEEKKPSPLKGLTFVITGTLPKPREEVKEMIEKAGGKVSSSVSKNTDYLLVGEDPGSKLAKAQALRVKTLSYEEFLKMLE

http://purl.uniprot.org/uniprot/B5YIF8#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YIF8#attribution-205EE578AABEFC2A9D16E41084DB3D31
manual: true
evidence: ECO_0000255
source: MF_01588

B5YJ89
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 74
mnemonic: DTD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP34666DAC82CE7EC4
alternative name: SIPBCD097FF3A2902C8
enzyme: http://purl.uniprot.org/enzyme/3.1.1.96
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP6F1EB9B43F17E601
annotation: SIP99747ADAEAAB087F
annotation: SIP70DA87B36A5B2D03
annotation: SIPF0B3E6C265D6C3ED
annotation: SIPB6A4983F9635BE5C
annotation: SIP140086B1B4BEB129
annotation: SIP13BF4A744FDE244C
annotation: PRO_1000127590
annotation: SIP245827F81552D1EC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/820
classified with: GO_0005737
classified with: GO_0051500
classified with: GO_0106026
classified with: GO_0043908
classified with: GO_0000049
classified with: GO_0019478
classified with: GO_0006399
sequence: MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR
proteome: Chromosome

B5YJ89-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1490
type: Resource
database: eggNOG
comment: Bacteria

cd00563
type: Resource
database: CDD
comment: Dtyr_deacylase
signature sequence match: CDD cd00563 match 1

http://purl.uniprot.org/gene3d/3.50.80.10
type: Resource
database: Gene3D
comment: D-tyrosyl-tRNA(Tyr) deacylase
signature sequence match: Gene3D 3.50.80.10 match 1

MF_00518
type: Resource
database: HAMAP
comment: Deacylase_Dtd
signature sequence match: HAMAP MF 00518 match 1

IPR003732
type: Resource
database: InterPro
comment: Daa-tRNA_deacyls_DTD

IPR023509
type: Resource
database: InterPro
comment: DTD-like_sf

PTHR10472:SF5
type: Resource
database: PANTHER
comment: D-AMINOACYL-TRNA DEACYLASE 1
signature sequence match: PANTHER PTHR10472:SF5 match 1

PTHR10472
type: Resource
database: PANTHER
comment: D-TYROSYL-TRNA TYR DEACYLASE
signature sequence match: PANTHER PTHR10472 match 1

PF02580
type: Resource
database: Pfam
comment: Tyr_Deacylase
signature sequence match: Pfam PF02580 match 1

SSF69500
type: Resource
database: SUPFAM
comment: DTD-like
signature sequence match: SUPFAM SSF69500 match 1

TIGR00256
type: Resource
database: TIGRFAMs
comment: D-tyrosyl-tRNA(Tyr) deacylase
signature sequence match: TIGRFAMs TIGR00256 match 1

SIP34666DAC82CE7EC4
type: Structured Name
full name: D-aminoacyl-tRNA deacylase
short name: DTD
ec name: 3.1.1.96

SIPBCD097FF3A2902C8
type: Structured Name
full name: Gly-tRNA(Ala) deacylase

dtd
type: Gene
locus name: THEYE_A0459

SIP6F1EB9B43F17E601
type: Function Annotation
comment: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.

SIPF0B3E6C265D6C3ED
type: Subunit Annotation
comment: Homodimer.

SIP140086B1B4BEB129
type: Domain Annotation
comment: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.

SIP13BF4A744FDE244C
type: Similarity Annotation
comment: Belongs to the DTD family.

PRO_1000127590
type: Chain Annotation
comment: D-aminoacyl-tRNA deacylase
mass: 16252
range: 18636006076463406tt1tt146

18636006076463406tt1
type: Position
type: ExactPosition
position: 1
reference: MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR

18636006076463406tt146
type: Position
type: ExactPosition
position: 146
reference: MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR

SIP245827F81552D1EC
type: Motif Annotation
comment: Gly-cisPro motif, important for rejection of L-amino acids
range: 18636006076463406tt137tt138

18636006076463406tt137
type: Position
type: ExactPosition
position: 137
reference: MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR

18636006076463406tt138
type: Position
type: ExactPosition
position: 138
reference: MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR

MIALLQRVNKASVEVGGETISEIGKGILIFLGIDKKDSKKDVEYLADKVVNLRIFEDNNSKMNLSIKDVGGEIMVVSEFTLAGDCKKGNRPSFDKAMPPEEAEKLYRDFIDSLRSKGIPVKEGVFRSFMHVSLINEGPVTFILNTR
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 16252

http://purl.uniprot.org/uniprot/B5YJ89#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJ89#attribution-2FCA4DC1F7A9F9BB916B3F5139223798
manual: true
evidence: ECO_0000255
source: MF_00518

B5YI09
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 76
mnemonic: DXR_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP98B9B9057F9702D6
alternative name: SIPF3A9D7FEC1BB3DED
alternative name: SIP32C843B5F7958A87
enzyme: http://purl.uniprot.org/enzyme/1.1.1.267
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP1FE3FCB659645C81
annotation: SIP9C4C6C319004ED40
annotation: SIPC45D96FE4A9E83EB
annotation: SIP5FD94BF003519ED3
annotation: SIP7771463A095FCD0C
annotation: PRO_1000098522
annotation: SIP8A84201C7962934D
annotation: SIP29B18B07C1AC9C87
annotation: SIPDE38F26CD2698ECB
annotation: SIP3B868C5DB5BCFE56
annotation: SIP59B0362D8687BBA8
annotation: SIPCD16662DAEF1CA7C
annotation: SIPF460E8A87C95656B
annotation: SIP50DC0B96D8988B14
annotation: SIPBB64DF8A5981E4D6
annotation: SIPB12508C34E62FC4F
annotation: SIP39747860DC864AEC
annotation: SIPD35CC252EF0B223E
annotation: SIPEF514A27452E887D
annotation: SIPCB5B98189DAEE708
annotation: SIP74C363078C4240DA
annotation: SIP9A7405315A3D4BB1
annotation: SIP7FC12545609ACB49
annotation: SIPB48CC20A49252E2C
annotation: SIPC21C162E1AED283C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/414
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0030604
classified with: GO_0030145
classified with: GO_0070402
classified with: GO_0051484
sequence: B5YI09-1
proteome: Chromosome

B5YI09-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0743
type: Resource
database: eggNOG
comment: Bacteria

MF_00183
type: Resource
database: HAMAP
comment: DXP_reductoisom
signature sequence match: HAMAP MF 00183 match 1

IPR003821
type: Resource
database: InterPro
comment: DXP_reductoisomerase

IPR013644
type: Resource
database: InterPro
comment: DXP_reductoisomerase_C

IPR013512
type: Resource
database: InterPro
comment: DXP_reductoisomerase_N

IPR026877
type: Resource
database: InterPro
comment: DXPR_C

IPR036169
type: Resource
database: InterPro
comment: DXPR_C_sf

PTHR30525
type: Resource
database: PANTHER
comment: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE
signature sequence match: PANTHER PTHR30525 match 1

PTHR30525:SF0
type: Resource
database: PANTHER
comment: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, CHLOROPLASTIC
signature sequence match: PANTHER PTHR30525:SF0 match 1

PF08436
type: Resource
database: Pfam
comment: DXP_redisom_C
signature sequence match: Pfam PF08436 match 1

PF02670
type: Resource
database: Pfam
comment: DXP_reductoisom
signature sequence match: Pfam PF02670 match 1

PF13288
type: Resource
database: Pfam
comment: DXPR_C
signature sequence match: Pfam PF13288 match 1

PIRSF006205
type: Resource
database: PIRSF
comment: Dxp_reductismrs
signature sequence match: PIRSF PIRSF006205 match 1

SSF69055
type: Resource
database: SUPFAM
comment: 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
signature sequence match: SUPFAM SSF69055 match 1

SSF55347
type: Resource
database: SUPFAM
comment: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
signature sequence match: SUPFAM SSF55347 match 1

TIGR00243
type: Resource
database: TIGRFAMs
comment: Dxr
signature sequence match: TIGRFAMs TIGR00243 match 1

SIP98B9B9057F9702D6
type: Structured Name
full name: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
short name: DXP reductoisomerase
ec name: 1.1.1.267

SIPF3A9D7FEC1BB3DED
type: Structured Name
full name: 1-deoxyxylulose-5-phosphate reductoisomerase

SIP32C843B5F7958A87
type: Structured Name
full name: 2-C-methyl-D-erythritol 4-phosphate synthase

dxr
type: Gene
locus name: THEYE_A0226

SIP1FE3FCB659645C81
type: Function Annotation
comment: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

SIP7771463A095FCD0C
type: Similarity Annotation
comment: Belongs to the DXR family.

PRO_1000098522
type: Chain Annotation
comment: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
mass: 41939
range: 18636006059161902tt1tt381

18636006059161902tt1
type: Position
type: ExactPosition
position: 1
reference: B5YI09-1

18636006059161902tt381
type: Position
type: ExactPosition
position: 381
reference: B5YI09-1

18636006059161902tt10
type: Position
type: ExactPosition
position: 10
reference: B5YI09-1

18636006059161902tt11
type: Position
type: ExactPosition
position: 11
reference: B5YI09-1

18636006059161902tt12
type: Position
type: ExactPosition
position: 12
reference: B5YI09-1

18636006059161902tt13
type: Position
type: ExactPosition
position: 13
reference: B5YI09-1

18636006059161902tt120
type: Position
type: ExactPosition
position: 120
reference: B5YI09-1

18636006059161902tt121
type: Position
type: ExactPosition
position: 121
reference: B5YI09-1

18636006059161902tt122
type: Position
type: ExactPosition
position: 122
reference: B5YI09-1

18636006059161902tt146
type: Position
type: ExactPosition
position: 146
reference: B5YI09-1

18636006059161902tt147
type: Position
type: ExactPosition
position: 147
reference: B5YI09-1

18636006059161902tt148
type: Position
type: ExactPosition
position: 148
reference: B5YI09-1

18636006059161902tt172
type: Position
type: ExactPosition
position: 172
reference: B5YI09-1

18636006059161902tt195
type: Position
type: ExactPosition
position: 195
reference: B5YI09-1

18636006059161902tt201
type: Position
type: ExactPosition
position: 201
reference: B5YI09-1

18636006059161902tt208
type: Position
type: ExactPosition
position: 208
reference: B5YI09-1

18636006059161902tt213
type: Position
type: ExactPosition
position: 213
reference: B5YI09-1

18636006059161902tt214
type: Position
type: ExactPosition
position: 214
reference: B5YI09-1

18636006059161902tt217
type: Position
type: ExactPosition
position: 217
reference: B5YI09-1

B5YI09-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 41939
value: MKKVVILGSTGSIGKNALEVIRKFPDKFKVLGLAAKSSVNILEEQIKEFNPQYVAVFDKKACDELRKKVKNLEILKGNEGICKLAKLKEADIILSAIVGAAGLIPTFEAVKEGKTIGVANKESFVMAGELIKKQGKISGAKIIPVDSEHSAVFQCINGCNKPYIKKIWLTASGGPFRGKKSYEIENVTPQEALNHPKWKMGKRITIDSATLMNKGFEVIEAHYLFDMPAENIGVLIHPQSIIHCLVEFIDGTYLAQMSNPDMKAPIALALSFPERLPEIVPPIDWSITTKLQFEIPDTEVFPCLKLAYEALNAGGSMPAVLNAADEVAVEAFLSGRLKFKEIYKIIKKVMDAHKIVSVSSIEEVLEADSWARKMAKKEIGE

http://purl.uniprot.org/uniprot/B5YI09#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YI09#attribution-46B1CDA2A36C7BCBDCF0CCD986A4E65F
manual: true
evidence: ECO_0000255
source: MF_00183

B5YJ32
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 73
mnemonic: EFP_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP42E8051B8F3706F6
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP5168D3B6C8243EA8
annotation: SIP04510096B1B8FD92
annotation: SIP3D4A47A8E4609E3B
annotation: SIP0BE3C682C774C471
annotation: PRO_1000117907
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003746
sequence: MISTSEFKKGLKIEYKGEPYEIIDFQHVKMQQRAPIVRTKIKHLKTGRVLEENFPAGEKFEKPELEEKQMQYLYSQGDSYVFMDMESYEQISIPKERIGDAIYYIKDEMIVDVIYYKGEPLVIEPPMFVELRVAETEPAFKGDTASGGTKPAKLETGLTVKVPFHIQTGDLLKIDTRTGEYIEKVKE
proteome: Chromosome

B5YJ32-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0231
type: Resource
database: eggNOG
comment: Bacteria

cd04470
type: Resource
database: CDD
comment: S1_EF-P_repeat_1
signature sequence match: CDD cd04470 match 1

cd05794
type: Resource
database: CDD
comment: S1_EF-P_repeat_2
signature sequence match: CDD cd05794 match 1

MF_00141
type: Resource
database: HAMAP
comment: EF_P
signature sequence match: HAMAP MF 00141 match 1

IPR015365
type: Resource
database: InterPro
comment: Elong-fact-P_C

IPR014722
type: Resource
database: InterPro
comment: Rib_L2_dom2

IPR020599
type: Resource
database: InterPro
comment: Transl_elong_fac_P/YeiP

IPR013185
type: Resource
database: InterPro
comment: Transl_elong_KOW-like

IPR001059
type: Resource
database: InterPro
comment: Transl_elong_P/YeiP_cen

IPR013852
type: Resource
database: InterPro
comment: Transl_elong_P/YeiP_CS

IPR011768
type: Resource
database: InterPro
comment: Transl_elongation_fac_P

IPR008991
type: Resource
database: InterPro
comment: Translation_prot_SH3-like_sf

PTHR30053
type: Resource
database: PANTHER
comment: ELONGATION FACTOR P
signature sequence match: PANTHER PTHR30053 match 1

PTHR30053:SF12
type: Resource
database: PANTHER
comment: ELONGATION FACTOR P (EF-P) FAMILY PROTEIN
signature sequence match: PANTHER PTHR30053:SF12 match 1

PF01132
type: Resource
database: Pfam
comment: EFP
signature sequence match: Pfam PF01132 match 1

PF08207
type: Resource
database: Pfam
comment: EFP_N
signature sequence match: Pfam PF08207 match 1

PF09285
type: Resource
database: Pfam
comment: Elong-fact-P_C
signature sequence match: Pfam PF09285 match 1

PIRSF005901
type: Resource
database: PIRSF
comment: EF-P
signature sequence match: PIRSF PIRSF005901 match 1

SM01185
type: Resource
database: SMART
comment: EFP
signature sequence match: SMART SM01185 match 1

SM00841
type: Resource
database: SMART
comment: Elong-fact-P_C
signature sequence match: SMART SM00841 match 1

SSF50104
type: Resource
database: SUPFAM
comment: Translation proteins SH3-like domain
signature sequence match: SUPFAM SSF50104 match 1

TIGR00038
type: Resource
database: TIGRFAMs
comment: efp
signature sequence match: TIGRFAMs TIGR00038 match 1

PS01275
type: Resource
database: PROSITE
comment: EFP
signature sequence match: PROSITE PS01275 match 1

SIP42E8051B8F3706F6
type: Structured Name
full name: Elongation factor P
short name: EF-P

efp
type: Gene
locus name: THEYE_A0400

SIP5168D3B6C8243EA8
type: Function Annotation
comment: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

SIP0BE3C682C774C471
type: Similarity Annotation
comment: Belongs to the elongation factor P family.

PRO_1000117907
type: Chain Annotation
comment: Elongation factor P
mass: 21610
range: 18636006076133934tt1tt187

18636006076133934tt1
type: Position
type: ExactPosition
position: 1
reference: MISTSEFKKGLKIEYKGEPYEIIDFQHVKMQQRAPIVRTKIKHLKTGRVLEENFPAGEKFEKPELEEKQMQYLYSQGDSYVFMDMESYEQISIPKERIGDAIYYIKDEMIVDVIYYKGEPLVIEPPMFVELRVAETEPAFKGDTASGGTKPAKLETGLTVKVPFHIQTGDLLKIDTRTGEYIEKVKE

18636006076133934tt187
type: Position
type: ExactPosition
position: 187
reference: MISTSEFKKGLKIEYKGEPYEIIDFQHVKMQQRAPIVRTKIKHLKTGRVLEENFPAGEKFEKPELEEKQMQYLYSQGDSYVFMDMESYEQISIPKERIGDAIYYIKDEMIVDVIYYKGEPLVIEPPMFVELRVAETEPAFKGDTASGGTKPAKLETGLTVKVPFHIQTGDLLKIDTRTGEYIEKVKE

MISTSEFKKGLKIEYKGEPYEIIDFQHVKMQQRAPIVRTKIKHLKTGRVLEENFPAGEKFEKPELEEKQMQYLYSQGDSYVFMDMESYEQISIPKERIGDAIYYIKDEMIVDVIYYKGEPLVIEPPMFVELRVAETEPAFKGDTASGGTKPAKLETGLTVKVPFHIQTGDLLKIDTRTGEYIEKVKE
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 21610

http://purl.uniprot.org/uniprot/B5YJ32#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJ32#attribution-68AEDF1632F0BC61D700CEF2CC98DAC2
manual: true
evidence: ECO_0000255
source: MF_00141

B5YGE0
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 71
mnemonic: EFTS_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPFF0ED0AA27B8537C
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPBC0AE8A2CCA9980E
annotation: SIP4A8765F6F003CCB6
annotation: SIP32AAD90B7A23EF5A
annotation: PRO_1000189893
annotation: SIPC1F1279963356173
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003746
classified with: GO_0006414
sequence: MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE
proteome: Chromosome

B5YGE0-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0264
type: Resource
database: eggNOG
comment: Bacteria

cd14275
type: Resource
database: CDD
comment: UBA_EF-Ts
signature sequence match: CDD cd14275 match 1

http://purl.uniprot.org/gene3d/1.10.8.10
type: Resource
database: Gene3D
comment: DNA helicase RuvA subunit, C-terminal domain
signature sequence match: Gene3D 1.10.8.10 match 1

http://purl.uniprot.org/gene3d/3.30.479.20
type: Resource
database: Gene3D
comment: Elongation factor Ts, dimerisation domain
signature sequence match: Gene3D 3.30.479.20 match 1

MF_00050
type: Resource
database: HAMAP
comment: EF_Ts
signature sequence match: HAMAP MF 00050 match 1

IPR036402
type: Resource
database: InterPro
comment: EF-Ts_dimer_sf

IPR001816
type: Resource
database: InterPro
comment: Transl_elong_EFTs/EF1B

IPR014039
type: Resource
database: InterPro
comment: Transl_elong_EFTs/EF1B_dimer

IPR018101
type: Resource
database: InterPro
comment: Transl_elong_Ts_CS

IPR009060
type: Resource
database: InterPro
comment: UBA-like_sf

PTHR11741
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TS
signature sequence match: PANTHER PTHR11741 match 1

PTHR11741:SF0
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TS, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11741:SF0 match 1

PF00889
type: Resource
database: Pfam
comment: EF_TS
signature sequence match: Pfam PF00889 match 1

SSF54713
type: Resource
database: SUPFAM
comment: Elongation factor Ts (EF-Ts), dimerisation domain
signature sequence match: SUPFAM SSF54713 match 1

SSF46934
type: Resource
database: SUPFAM
comment: UBA-like
signature sequence match: SUPFAM SSF46934 match 1

TIGR00116
type: Resource
database: TIGRFAMs
comment: tsf
signature sequence match: TIGRFAMs TIGR00116 match 1

PS01126
type: Resource
database: PROSITE
comment: EF_TS_1
signature sequence match: PROSITE PS01126 match 1

PS01127
type: Resource
database: PROSITE
comment: EF_TS_2
signature sequence match: PROSITE PS01127 match 1

SIPFF0ED0AA27B8537C
type: Structured Name
full name: Elongation factor Ts
short name: EF-Ts

tsf
type: Gene
locus name: THEYE_A1542

SIPBC0AE8A2CCA9980E
type: Function Annotation
comment: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.

SIP32AAD90B7A23EF5A
type: Similarity Annotation
comment: Belongs to the EF-Ts family.

PRO_1000189893
type: Chain Annotation
comment: Elongation factor Ts
mass: 22832
range: 18636006026981422tt1tt199

18636006026981422tt1
type: Position
type: ExactPosition
position: 1
reference: MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE

18636006026981422tt199
type: Position
type: ExactPosition
position: 199
reference: MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE

SIPC1F1279963356173
type: Region Annotation
comment: Involved in Mg(2+) ion dislocation from EF-Tu
range: 18636006026981422tt80tt83

18636006026981422tt80
type: Position
type: ExactPosition
position: 80
reference: MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE

18636006026981422tt83
type: Position
type: ExactPosition
position: 83
reference: MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE

MAITAQMVKELREKTGAGMMECKKALETSGGDFNKAIDILRQKGLATAQKKASREAKEGIITSYIHMDKIGVMLELNCETDFVARNEEFRQLAKDIAMQIAASNPQYIQREDIPQEVIEKEKEIYKSQIKGNKPPQVIEKIVEGKLEKFFEEMCLLDQPFIKEPEKKIKDLITEKVAKFGENIMVRRFVRFQVGQTQDE
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 22832

http://purl.uniprot.org/uniprot/B5YGE0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YGE0#attribution-7640461A89C5EECC81FABE53E97D5FB6
manual: true
evidence: ECO_0000255
source: MF_00050

B5YIX2
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 61
mnemonic: FLGH_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPDBE289F5FB363F43
alternative name: SIP6F2C97754F1C709B
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP8531D1A084F5DDB3
annotation: SIP1720F8EB6C18A86E
annotation: SIP4189DC844BE38D63
annotation: SIP74E52CE85A015BCE
annotation: SIP8431CFA6DC3D7EAB
annotation: PRO_1000134833
annotation: SIPC9EA8D7245B1400E
annotation: SIPA074FAD4C655F0D9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/975
classified with: http://purl.uniprot.org/keywords/998
classified with: http://purl.uniprot.org/keywords/564
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/732
classified with: GO_0009427
classified with: GO_0009279
classified with: GO_0003774
classified with: GO_0071973
sequence: B5YIX2-1
proteome: Chromosome

B5YIX2-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG2063
type: Resource
database: eggNOG
comment: Bacteria

MF_00415
type: Resource
database: HAMAP
comment: FlgH
signature sequence match: HAMAP MF 00415 match 1

IPR000527
type: Resource
database: InterPro
comment: Flag_Lring

PTHR34933
type: Resource
database: PANTHER
comment: FLAGELLAR L-RING PROTEIN
signature sequence match: PANTHER PTHR34933 match 1

PTHR34933:SF1
type: Resource
database: PANTHER
comment: FLAGELLAR L-RING PROTEIN
signature sequence match: PANTHER PTHR34933:SF1 match 1

PF02107
type: Resource
database: Pfam
comment: FlgH
signature sequence match: Pfam PF02107 match 1

PS51257
type: Resource
database: PROSITE
comment: PROKAR_LIPOPROTEIN
signature sequence match: PROSITE PS51257 match 1

SIPDBE289F5FB363F43
type: Structured Name
full name: Flagellar L-ring protein

SIP6F2C97754F1C709B
type: Structured Name
full name: Basal body L-ring protein

flgH
type: Gene
locus name: THEYE_A2059

SIP8531D1A084F5DDB3
type: Function Annotation
comment: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.

SIP1720F8EB6C18A86E
type: Subunit Annotation
comment: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

SIP74E52CE85A015BCE
type: Similarity Annotation
comment: Belongs to the FlgH family.

18636006061781550tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIX2-1

18636006061781550tt16
type: Position
type: ExactPosition
position: 16
reference: B5YIX2-1

PRO_1000134833
type: Chain Annotation
comment: Flagellar L-ring protein
mass: 24468
range: 18636006061781550tt17tt238

18636006061781550tt17
type: Position
type: ExactPosition
position: 17
reference: B5YIX2-1

18636006061781550tt238
type: Position
type: ExactPosition
position: 238
reference: B5YIX2-1

SIPC9EA8D7245B1400E
type: Lipidation Annotation
comment: N-palmitoyl cysteine
range: 18636006061781550tt17tt17

SIPA074FAD4C655F0D9
type: Lipidation Annotation
comment: S-diacylglycerol cysteine
range: 18636006061781550tt17tt17

B5YIX2-1
type: Simple Sequence
modified: 2008-11-25
version: 1
precursor: true
mass: 26318
value: MRKLILISLCIFFLASCSELQEVRDIKNAGMPPKYYPEPPQTQVASEGSLWRNKASLYEDKKARRVNDLVTILINESTSAQKTASTTASRDSSTNYGLDTFFGMNTDFNIHNLPLINGFYKAGNVFSPSVKGSATSDFKGDGDTARTGKITGTITAKVVEVLPNGNLVIESRKEVIVNNEKEILVLRGIIRPDDISQSNTILSQYVADAQIYLVGEGTLGDKQSQGWLVRFLDKIWPF

http://purl.uniprot.org/uniprot/B5YIX2#attribution-508D8F6E97012976A2DF69E64E09318C
manual: true
evidence: ECO_0000255
source: MF_00415

B5YIL6
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 79
mnemonic: FMT_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPB847825D2C1252D7
enzyme: http://purl.uniprot.org/enzyme/2.1.2.9
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPD34082F3D4F3B630
annotation: SIPD7434B49002D798D
annotation: SIP349F14DCBC8FA5BC
annotation: PRO_1000098455
annotation: SIPCFF0AD8952893084
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005829
classified with: GO_0004479
classified with: GO_0071951
sequence: B5YIL6-1
proteome: Chromosome

B5YIL6-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0223
type: Resource
database: eggNOG
comment: Bacteria

cd08646
type: Resource
database: CDD
comment: FMT_core_Met-tRNA-FMT_N
signature sequence match: CDD cd08646 match 1

cd08704
type: Resource
database: CDD
comment: Met_tRNA_FMT_C
signature sequence match: CDD cd08704 match 1

MF_00182
type: Resource
database: HAMAP
comment: Formyl_trans
signature sequence match: HAMAP MF 00182 match 1

IPR005794
type: Resource
database: InterPro
comment: Fmt

IPR005793
type: Resource
database: InterPro
comment: Formyl_trans_C

IPR002376
type: Resource
database: InterPro
comment: Formyl_transf_N

IPR036477
type: Resource
database: InterPro
comment: Formyl_transf_N_sf

IPR011034
type: Resource
database: InterPro
comment: Formyl_transferase-like_C_sf

IPR044135
type: Resource
database: InterPro
comment: Met-tRNA-FMT_C

IPR041711
type: Resource
database: InterPro
comment: Met-tRNA-FMT_N

PTHR11138
type: Resource
database: PANTHER
comment: METHIONYL-TRNA FORMYLTRANSFERASE
signature sequence match: PANTHER PTHR11138 match 1

PTHR11138:SF5
type: Resource
database: PANTHER
comment: METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11138:SF5 match 1

PF02911
type: Resource
database: Pfam
comment: Formyl_trans_C
signature sequence match: Pfam PF02911 match 1

PF00551
type: Resource
database: Pfam
comment: Formyl_trans_N
signature sequence match: Pfam PF00551 match 1

SSF50486
type: Resource
database: SUPFAM
comment: FMT C-terminal domain-like
signature sequence match: SUPFAM SSF50486 match 1

SSF53328
type: Resource
database: SUPFAM
comment: Formyltransferase
signature sequence match: SUPFAM SSF53328 match 1

TIGR00460
type: Resource
database: TIGRFAMs
comment: fmt
signature sequence match: TIGRFAMs TIGR00460 match 1

SIPB847825D2C1252D7
type: Structured Name
full name: Methionyl-tRNA formyltransferase
ec name: 2.1.2.9

fmt
type: Gene
locus name: THEYE_A0328

SIPD34082F3D4F3B630
type: Function Annotation
comment: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.

SIP349F14DCBC8FA5BC
type: Similarity Annotation
comment: Belongs to the Fmt family.

PRO_1000098455
type: Chain Annotation
comment: Methionyl-tRNA formyltransferase
mass: 33993
range: 18636006060996142tt1tt308

18636006060996142tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIL6-1

18636006060996142tt308
type: Position
type: ExactPosition
position: 308
reference: B5YIL6-1

18636006060996142tt111
type: Position
type: ExactPosition
position: 111
reference: B5YIL6-1

18636006060996142tt114
type: Position
type: ExactPosition
position: 114
reference: B5YIL6-1

B5YIL6-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 33993
value: MSSGIIFFGTPEFAVPSLKALISRGEKILLVVTQPDKPKGRGKNLQAPEIKKVALQCGLPLCQPEKMKDDNFIKKLKSLNPEFAIVVAYGKILPKEILEIPKHGCINLHASLLPKYRGAAPIQWALINGEKITGVTTMIIDEGLDTGPILLQKEISINDEDNAETLSEKLSVVGAELIIETIDKMRKGIITPKPQTGEITYAPQLKKDDGKINWNNSARKIFNLVRGTYPWPCAYSFLKDERVKIIKTEVLEGNAAPGLIIKAKNELIVGTQEGLLRILLIQPEGKKIMTAKEFISGRKINEGMDSFS

http://purl.uniprot.org/uniprot/B5YIL6#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YIL6#attribution-7ADB9D678307BD581F4CF2062C7F6356
manual: true
evidence: ECO_0000255
source: MF_00182

B5YJV1
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 77
mnemonic: FOLD_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPB0E7861556C8069B
domain: SIP48F851C727976C5B
domain: SIP7FDA6903BF270483
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPF38A8D0561AD9A4E
annotation: SIP2B4A8B58575FEB41
annotation: SIP07FD3156FEB8C7CD
annotation: SIP2744287CA3B5AC94
annotation: SIP29DB29C074B2916A
annotation: SIPA81B6C8EF0D335F5
annotation: PRO_1000147534
annotation: SIPEA2AC3A194E980D7
annotation: SIP006D1BD5F7CA6179
annotation: SIPFC3B97CBCCCD05C9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/368
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/511
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/554
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/658
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0004477
classified with: GO_0004488
classified with: GO_0000105
classified with: GO_0009086
classified with: GO_0006164
classified with: GO_0035999
sequence: B5YJV1-1
proteome: Chromosome

B5YJV1-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0190
type: Resource
database: eggNOG
comment: Bacteria

cd01080
type: Resource
database: CDD
comment: NAD_bind_m-THF_DH_Cyclohyd
signature sequence match: CDD cd01080 match 1

MF_01576
type: Resource
database: HAMAP
comment: THF_DHG_CYH
signature sequence match: HAMAP MF 01576 match 1

IPR000672
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase

IPR020630
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_cat_dom

IPR020867
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_CS

IPR020631
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_NAD-bd_dom

PTHR48099:SF5
type: Resource
database: PANTHER
comment: C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC
signature sequence match: PANTHER PTHR48099:SF5 match 1

PTHR48099
type: Resource
database: PANTHER
comment: C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED
signature sequence match: PANTHER PTHR48099 match 1

PF00763
type: Resource
database: Pfam
comment: THF_DHG_CYH
signature sequence match: Pfam PF00763 match 1

PF02882
type: Resource
database: Pfam
comment: THF_DHG_CYH_C
signature sequence match: Pfam PF02882 match 1

PR00085
type: Resource
database: PRINTS
comment: THFDHDRGNASE

PS00766
type: Resource
database: PROSITE
comment: THF_DHG_CYH_1
signature sequence match: PROSITE PS00766 match 1

PS00767
type: Resource
database: PROSITE
comment: THF_DHG_CYH_2
signature sequence match: PROSITE PS00767 match 1

SIPB0E7861556C8069B
type: Structured Name
full name: Bifunctional protein FolD

SIP1DCE05B86FF5482A
type: Structured Name
full name: Methylenetetrahydrofolate dehydrogenase
ec name: 1.5.1.5

SIPC5E9CCE6F8486257
type: Structured Name
full name: Methenyltetrahydrofolate cyclohydrolase
ec name: 3.5.4.9

folD
type: Gene
locus name: THEYE_A0674

SIPF38A8D0561AD9A4E
type: Function Annotation
comment: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.

SIP29DB29C074B2916A
type: Subunit Annotation
comment: Homodimer.

SIPA81B6C8EF0D335F5
type: Similarity Annotation
comment: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

PRO_1000147534
type: Chain Annotation
comment: Bifunctional protein FolD
mass: 31538
range: 18636006078427438tt1tt286

18636006078427438tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJV1-1

18636006078427438tt286
type: Position
type: ExactPosition
position: 286
reference: B5YJV1-1

18636006078427438tt165
type: Position
type: ExactPosition
position: 165
reference: B5YJV1-1

18636006078427438tt167
type: Position
type: ExactPosition
position: 167
reference: B5YJV1-1

18636006078427438tt190
type: Position
type: ExactPosition
position: 190
reference: B5YJV1-1

18636006078427438tt231
type: Position
type: ExactPosition
position: 231
reference: B5YJV1-1

B5YJV1-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 31538
value: MSAEILDGKSLALKIKEELKKEVQDLKNQGINPCLAVVLVGENKSSQKYVSFKEKTCKELDIQSLVFKLPENTEETSLIKLIDELNENSQVNGILIQLPLPKHLNQNKVLERINPFKDVDGFTPFCLGRLLIDSPLFIPCTPKGIIRMLDEYKINLEGKQAVVIGRSIIVGKPLSLLLLKRNATVTMCHSKTINLQDITKKADILCVAIGREKFITSNMIKKGAVVIDIGINVTASGKVVGDVNFDDVKEKASYITPVPGGVGPMTIAMLMENAIYAAKLQKRVVK

http://purl.uniprot.org/uniprot/B5YJV1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJV1#attribution-F069A5E3914EDBC44119710B6922B871
manual: true
evidence: ECO_0000255
source: MF_01576

B5YJE1
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 68
mnemonic: FTHS_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP1AE76A05755D2324
alternative name: SIPCF7F49F2D1E850C1
enzyme: http://purl.uniprot.org/enzyme/6.3.4.3
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPC786C7D1853D3962
annotation: SIP462896A82588587E
annotation: SIP72251836A354BF91
annotation: PRO_1000146709
annotation: SIP1ECD32BD86B4B3B1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/554
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0004329
classified with: GO_0035999
sequence: B5YJE1-1
proteome: Chromosome

B5YJE1-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG2759
type: Resource
database: eggNOG
comment: Bacteria

cd00477
type: Resource
database: CDD
comment: FTHFS
signature sequence match: CDD cd00477 match 1

http://purl.uniprot.org/gene3d/3.30.1510.10
type: Resource
database: Gene3D
comment: Domain 2, N(10)-formyltetrahydrofolate synthetase
signature sequence match: Gene3D 3.30.1510.10 match 1

http://purl.uniprot.org/gene3d/3.10.410.10
type: Resource
database: Gene3D
comment: Formyltetrahydrofolate synthetase, domain 3
signature sequence match: Gene3D 3.10.410.10 match 1

MF_01543
type: Resource
database: HAMAP
comment: FTHFS
signature sequence match: HAMAP MF 01543 match 1

IPR000559
type: Resource
database: InterPro
comment: Formate_THF_ligase

IPR020628
type: Resource
database: InterPro
comment: Formate_THF_ligase_CS

PF01268
type: Resource
database: Pfam
comment: FTHFS
signature sequence match: Pfam PF01268 match 1

PS00721
type: Resource
database: PROSITE
comment: FTHFS_1
signature sequence match: PROSITE PS00721 match 1

SIP1AE76A05755D2324
type: Structured Name
full name: Formate--tetrahydrofolate ligase
ec name: 6.3.4.3

SIPCF7F49F2D1E850C1
type: Structured Name
full name: Formyltetrahydrofolate synthetase
short name: FHS
short name: FTHFS

fhs
type: Gene
locus name: THEYE_A0513

SIP72251836A354BF91
type: Similarity Annotation
comment: Belongs to the formate--tetrahydrofolate ligase family.

PRO_1000146709
type: Chain Annotation
comment: Formate--tetrahydrofolate ligase
mass: 64990
range: 18636006077313326tt1tt589

18636006077313326tt1
type: Position
type: ExactPosition
position: 1
reference: B5YJE1-1

18636006077313326tt589
type: Position
type: ExactPosition
position: 589
reference: B5YJE1-1

18636006077313326tt74
type: Position
type: ExactPosition
position: 74
reference: B5YJE1-1

18636006077313326tt81
type: Position
type: ExactPosition
position: 81
reference: B5YJE1-1

B5YJE1-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 64990
value: MLPEPVSCPDWLIAQEAEKRMKSIFQLAEELDIKKEELIPYGSYIAKIDYRKLYSRIKNNPNGKYIIVTAITPTPFGEGKSTTTIGLTQGLGKRGKKVSCAIRQPSAGPLMNIKGSAAGGGLSQCIPRTEFSLGFTGDINAVMNAHNLAMVALTSRMLHEANYSDEILKKRGLRRLDIDPKRVQMGWVIDFCVQALRKIVIGLGGKKDGITMESRFDIATSSELMAILSLVKDLKELKKRISSIVVAYSKTGNPITTEDLEVSGAMSALMLPAFNPNLIQTIEGQPVFVHAAPFANIAIGQSSIIADMVGLKLNEYHVTECGFGADIGFEKFWNIKCRTSGLKPDVAVLVATLRALKYHGADKDSPKIIPGNPLPKEYIEKNMQWLERGMKNLFHHIKIIKKSGLSIVVCINKFQSDTHEELDFVRKFCEEMGIPVAISEHWQKGGQGALELADFVIDACKNNSNFNFLYENSLPHISRIELIAREIYGADSVEFSPLALEKLQSINSKKEFSDFAICIAKTHLSLSDNPLLRGVPEGWQLFIRDILVFYGAKLIVPVAGEISLMPGTASTPNFRTIDVDLQTGKVTGI

http://purl.uniprot.org/uniprot/B5YJE1#attribution-B4C2FE07047A93F934B2E4CA9A149808
manual: true
evidence: ECO_0000255
source: MF_01543

B5YL59
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 72
mnemonic: GATA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP2D1DF79B0D224CCE
enzyme: http://purl.uniprot.org/enzyme/6.3.5.7
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPC623499D0FCCA528
annotation: SIP0BDF614EED7239A7
annotation: SIPC26C96D72CF25BBA
annotation: SIP15E8DAB504C50F0D
annotation: PRO_1000095176
annotation: SIP5BBF77ECF5F6AF92
annotation: SIPA37E8DA297045C94
annotation: SIP54F8C92A4CC847D5
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0030956
classified with: GO_0005524
classified with: GO_0050567
classified with: GO_0006412
sequence: B5YL59-1
proteome: Chromosome

B5YL59-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0154
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.90.1300.10
type: Resource
database: Gene3D
comment: Amidase signature (AS) domain
signature sequence match: Gene3D 3.90.1300.10 match 1

MF_00120
type: Resource
database: HAMAP
comment: GatA
signature sequence match: HAMAP MF 00120 match 1

IPR000120
type: Resource
database: InterPro
comment: Amidase

IPR020556
type: Resource
database: InterPro
comment: Amidase_CS

IPR023631
type: Resource
database: InterPro
comment: Amidase_dom

IPR036928
type: Resource
database: InterPro
comment: AS_sf

IPR004412
type: Resource
database: InterPro
comment: GatA

PTHR11895:SF151
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A
signature sequence match: PANTHER PTHR11895:SF151 match 1

PTHR11895
type: Resource
database: PANTHER
comment: TRANSAMIDASE
signature sequence match: PANTHER PTHR11895 match 1

PF01425
type: Resource
database: Pfam
comment: Amidase
signature sequence match: Pfam PF01425 match 1

SSF75304
type: Resource
database: SUPFAM
comment: Amidase signature (AS) enzymes
signature sequence match: SUPFAM SSF75304 match 1

TIGR00132
type: Resource
database: TIGRFAMs
comment: gatA
signature sequence match: TIGRFAMs TIGR00132 match 1

PS00571
type: Resource
database: PROSITE
comment: AMIDASES
signature sequence match: PROSITE PS00571 match 1

SIP2D1DF79B0D224CCE
type: Structured Name
full name: Glutamyl-tRNA(Gln) amidotransferase subunit A
short name: Glu-ADT subunit A
ec name: 6.3.5.7

gatA
type: Gene
locus name: THEYE_A1150

SIPC623499D0FCCA528
type: Function Annotation
comment: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

SIPC26C96D72CF25BBA
type: Subunit Annotation
comment: Heterotrimer of A, B and C subunits.

SIP15E8DAB504C50F0D
type: Similarity Annotation
comment: Belongs to the amidase family. GatA subfamily.

PRO_1000095176
type: Chain Annotation
comment: Glutamyl-tRNA(Gln) amidotransferase subunit A
mass: 52963
range: 18636006109821230tt1tt484

18636006109821230tt1
type: Position
type: ExactPosition
position: 1
reference: B5YL59-1

18636006109821230tt484
type: Position
type: ExactPosition
position: 484
reference: B5YL59-1

SIP5BBF77ECF5F6AF92
type: Active Site Annotation
comment: Charge relay system
range: 18636006109821230tt78tt78

18636006109821230tt78
type: Position
type: ExactPosition
position: 78
reference: B5YL59-1

SIPA37E8DA297045C94
type: Active Site Annotation
comment: Charge relay system
range: 18636006109821230tt153tt153

18636006109821230tt153
type: Position
type: ExactPosition
position: 153
reference: B5YL59-1

SIP54F8C92A4CC847D5
type: Active Site Annotation
comment: Acyl-ester intermediate
range: 18636006109821230tt177tt177

18636006109821230tt177
type: Position
type: ExactPosition
position: 177
reference: B5YL59-1

B5YL59-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 52963
value: MELNKLKLTELVPLISKGEVRPHEIIIDVFKRVQEVEGKVKAYITLTVEKAYDMAREAENAIFSGKKSLLTGIPIAVKDNICTKGILTTCASKILYNFYPPYESTVTSKLLNNKYILIGKTNMDEFAMGSSTENSGFHVTKNPWDLERVPGGSSGGSAAAVAADECIAALGSDTGGSIRQPASFCGVVGLKPTYGRVSRFGLVAFASSLDQIGPITKCVADAALLMNVISGHDPMDSTSAPIESSDFTEYLGKEVKGIKIGIPKEYFIEGMDKEVEERIKDAIKELESLGCIPVEISLPHTEYAVATYYIIATSEASSNLARYDGVKYGLRVQGKDLLEMYMKTRSRGFGTEVKRRIMLGTYSLSAGYYEAYYKKAQQVRTLIKNDFEKAFEKVDFIVTPTAPSPAFKIGEKIDDPLQMYLSDIFTISVNLAGVPAISLPCGFSEKGLPVGLQIIGKPFDEAGILQLAYAYEQSTPWHKMKPLL

http://purl.uniprot.org/uniprot/B5YL59#attribution-211B70616AB828C89E92AFFD413454DC
manual: true
evidence: ECO_0000255
source: MF_00120

B5YL60
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 80
mnemonic: GATB_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPC71EC75D25D6A970
enzyme: http://purl.uniprot.org/enzyme/6.3.5.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP92AC1A0E59D4BF73
annotation: SIP800C7FF864FE4F10
annotation: SIPACEF34ED4C6070F6
annotation: SIPF18408C12A038BD6
annotation: SIPA8F0F312DF882FFF
annotation: PRO_1000117624
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0050566
classified with: GO_0005524
classified with: GO_0050567
classified with: GO_0070681
classified with: GO_0006412
sequence: B5YL60-1
proteome: Chromosome

B5YL60-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0064
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.150.380
type: Resource
database: Gene3D
comment: GatB domain, N-terminal subdomain
signature sequence match: Gene3D 1.10.150.380 match 1

MF_00121
type: Resource
database: HAMAP
comment: GatB
signature sequence match: HAMAP MF 00121 match 1

IPR004413
type: Resource
database: InterPro
comment: Apn/Gln-ADT_bsu

IPR017959
type: Resource
database: InterPro
comment: Asn/Gln-tRNA_amidoTrfase_suB/E

IPR006075
type: Resource
database: InterPro
comment: Asn/Gln-tRNA_Trfase_suB/E_cat

IPR018027
type: Resource
database: InterPro
comment: Asn/Gln_amidotransferase

IPR003789
type: Resource
database: InterPro
comment: Asn/Gln_tRNA_amidoTrase-B-like

IPR042114
type: Resource
database: InterPro
comment: GatB_C_1

IPR023168
type: Resource
database: InterPro
comment: GatB_Yqey_C_2

IPR017958
type: Resource
database: InterPro
comment: Gln-tRNA_amidoTrfase_suB_CS

IPR014746
type: Resource
database: InterPro
comment: Gln_synth/guanido_kin_cat_dom

PTHR11659
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED
signature sequence match: PANTHER PTHR11659 match 1

PTHR11659:SF0
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11659:SF0 match 1

PF02934
type: Resource
database: Pfam
comment: GatB_N
signature sequence match: Pfam PF02934 match 1

PF02637
type: Resource
database: Pfam
comment: GatB_Yqey
signature sequence match: Pfam PF02637 match 1

SM00845
type: Resource
database: SMART
comment: GatB_Yqey
signature sequence match: SMART SM00845 match 1

SSF89095
type: Resource
database: SUPFAM
comment: GatB/YqeY motif
signature sequence match: SUPFAM SSF89095 match 1

SSF55931
type: Resource
database: SUPFAM
comment: Glutamine synthetase/guanido kinase
signature sequence match: SUPFAM SSF55931 match 1

TIGR00133
type: Resource
database: TIGRFAMs
comment: gatB
signature sequence match: TIGRFAMs TIGR00133 match 1

PS01234
type: Resource
database: PROSITE
comment: GATB
signature sequence match: PROSITE PS01234 match 1

SIPC71EC75D25D6A970
type: Structured Name
full name: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
short name: Asp/Glu-ADT subunit B
ec name: 6.3.5.-

gatB
type: Gene
locus name: THEYE_A1151

SIP92AC1A0E59D4BF73
type: Function Annotation
comment: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).

SIPF18408C12A038BD6
type: Subunit Annotation
comment: Heterotrimer of A, B and C subunits.

SIPA8F0F312DF882FFF
type: Similarity Annotation
comment: Belongs to the GatB/GatE family. GatB subfamily.

PRO_1000117624
type: Chain Annotation
comment: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
mass: 54324
range: 18636006109884462tt1tt475

18636006109884462tt1
type: Position
type: ExactPosition
position: 1
reference: B5YL60-1

18636006109884462tt475
type: Position
type: ExactPosition
position: 475
reference: B5YL60-1

B5YL60-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 54324
value: MQYEAVIGLEVHAQLLTESKIFCGCSTQFGAEPNTQVCPVCLGMPGVLPVLNKKAVEYTVKTGLAMNCKIAPYSRFARKNYFYPDLPKGYQISQYELPLCEDGYLEIMLNGTKRKIRIKRIHLEEDAGKNIHDPSGYSFVDFNRTGVPLMEIVSEPDIRSPKEAALYMKKLRAILRYLGVCDGNLEQGSLRCDANVSVRPVGSTEFGVKTEIKNINSFRFVEKALEYEIKRQIKLIENGEKIIQETRLWDSQTGTTQSMRSKEEAHDYRYFPEPDLVPVVVSEDWIEKIKKDMPELPDQKIERFIKEYGLPQYDSEILTEEKALSEWFEEAVKLGGKPKEVANWIMVELLRLLNEEGKDINECSLKPIQLVELIELINKGTINRNTAKEVFEEMYKTGKTAEAIVREKGLTQISDDSVIIEAIKEVMNKNPKEVERFRNGEEKLIGFFVGQVMKITKGKANPKLVNELIFKILKE

http://purl.uniprot.org/uniprot/B5YL60#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YL60#attribution-566F024AB45254E6A93C8C84ADE6F906
manual: true
evidence: ECO_0000255
source: MF_00121

B5YHS7
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 66
mnemonic: GATC_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP3F06189354D3336F
enzyme: http://purl.uniprot.org/enzyme/6.3.5.-
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP41DD88EF9B0BB443
annotation: SIPA3D049F699B2A717
annotation: SIP4D59D72A39536B0F
annotation: SIP8F3E8C89425F9898
annotation: SIPCD6DA363C9622339
annotation: PRO_1000095324
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0050566
classified with: GO_0005524
classified with: GO_0050567
classified with: GO_0070681
classified with: GO_0006450
classified with: GO_0006412
sequence: MKISKEEVKHIAMLSRLELNEEEIGVYQEQLSRILDYIEKLNEIDTTLVEPTSHVIELKNVFRDDNVKGSISRDEALKNAPDQTDKFFRVPKIIE
proteome: Chromosome

B5YHS7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0721
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.20.60
type: Resource
database: Gene3D
comment: Glu-tRNAGln amidotransferase C subunit, N-terminal domain
signature sequence match: Gene3D 1.10.20.60 match 1

MF_00122
type: Resource
database: HAMAP
comment: GatC
signature sequence match: HAMAP MF 00122 match 1

IPR003837
type: Resource
database: InterPro
comment: Asp/Glu-ADT_csu

IPR036113
type: Resource
database: InterPro
comment: Asp/Glu-ADT_sf_sub_c

PTHR15004:SF0
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL
signature sequence match: PANTHER PTHR15004:SF0 match 1

PTHR15004
type: Resource
database: PANTHER
comment: UNCHARACTERIZED
signature sequence match: PANTHER PTHR15004 match 1

PF02686
type: Resource
database: Pfam
comment: Glu-tRNAGln
signature sequence match: Pfam PF02686 match 1

SSF141000
type: Resource
database: SUPFAM
comment: Glu-tRNAGln amidotransferase C subunit
signature sequence match: SUPFAM SSF141000 match 1

TIGR00135
type: Resource
database: TIGRFAMs
comment: gatC
signature sequence match: TIGRFAMs TIGR00135 match 1

SIP3F06189354D3336F
type: Structured Name
full name: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
short name: Asp/Glu-ADT subunit C
ec name: 6.3.5.-

gatC
type: Gene
locus name: THEYE_A1873

SIP41DD88EF9B0BB443
type: Function Annotation
comment: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).

SIP8F3E8C89425F9898
type: Subunit Annotation
comment: Heterotrimer of A, B and C subunits.

SIPCD6DA363C9622339
type: Similarity Annotation
comment: Belongs to the GatC family.

PRO_1000095324
type: Chain Annotation
comment: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
mass: 11086
range: 18636006044677934tt1tt95

18636006044677934tt1
type: Position
type: ExactPosition
position: 1
reference: MKISKEEVKHIAMLSRLELNEEEIGVYQEQLSRILDYIEKLNEIDTTLVEPTSHVIELKNVFRDDNVKGSISRDEALKNAPDQTDKFFRVPKIIE

18636006044677934tt95
type: Position
type: ExactPosition
position: 95
reference: MKISKEEVKHIAMLSRLELNEEEIGVYQEQLSRILDYIEKLNEIDTTLVEPTSHVIELKNVFRDDNVKGSISRDEALKNAPDQTDKFFRVPKIIE

MKISKEEVKHIAMLSRLELNEEEIGVYQEQLSRILDYIEKLNEIDTTLVEPTSHVIELKNVFRDDNVKGSISRDEALKNAPDQTDKFFRVPKIIE
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 11086

http://purl.uniprot.org/uniprot/B5YHS7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YHS7#attribution-BDF30789043FD672D4F4F6AF69885F87
manual: true
evidence: ECO_0000255
source: MF_00122

B5YJV0
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 72
mnemonic: GCH1_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP763AFDCB6FD786CE
alternative name: SIP06D5C4DD2158AF26
enzyme: http://purl.uniprot.org/enzyme/3.5.4.16
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP36887624C9E798A4
annotation: SIPD9FE43E7F1650E24
annotation: SIP3752FA502C521044
annotation: SIP36F0FA0A1C634DBC
annotation: PRO_1000100208
annotation: SIPF94E4560E8F82DAC
annotation: SIPD6016CB24447C9DD
annotation: SIP7DBF3EBF9F9E993C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/554
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0005525
classified with: GO_0003934
classified with: GO_0008270
classified with: GO_0035998
classified with: GO_0006730
classified with: GO_0006729
classified with: GO_0046654
sequence: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK
proteome: Chromosome

B5YJV0-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0302
type: Resource
database: eggNOG
comment: Bacteria

MF_00223
type: Resource
database: HAMAP
comment: FolE
signature sequence match: HAMAP MF 00223 match 1

IPR043133
type: Resource
database: InterPro
comment: GTP-CH-I_C/QueF

IPR043134
type: Resource
database: InterPro
comment: GTP-CH-I_N

IPR001474
type: Resource
database: InterPro
comment: GTP_CycHdrlase_I

IPR018234
type: Resource
database: InterPro
comment: GTP_CycHdrlase_I_CS

IPR020602
type: Resource
database: InterPro
comment: GTP_CycHdrlase_I_dom

PTHR11109:SF7
type: Resource
database: PANTHER
comment: GTP CYCLOHYDROLASE 1
signature sequence match: PANTHER PTHR11109:SF7 match 1

PTHR11109
type: Resource
database: PANTHER
comment: GTP CYCLOHYDROLASE I
signature sequence match: PANTHER PTHR11109 match 1

PF01227
type: Resource
database: Pfam
comment: GTP_cyclohydroI
signature sequence match: Pfam PF01227 match 1

SSF55620
type: Resource
database: SUPFAM
comment: Tetrahydrobiopterin biosynthesis enzymes-like
signature sequence match: SUPFAM SSF55620 match 1

TIGR00063
type: Resource
database: TIGRFAMs
comment: folE
signature sequence match: TIGRFAMs TIGR00063 match 1

PS00859
type: Resource
database: PROSITE
comment: GTP_CYCLOHYDROL_1_1
signature sequence match: PROSITE PS00859 match 1

PS00860
type: Resource
database: PROSITE
comment: GTP_CYCLOHYDROL_1_2
signature sequence match: PROSITE PS00860 match 1

SIP763AFDCB6FD786CE
type: Structured Name
full name: GTP cyclohydrolase 1
ec name: 3.5.4.16

SIP06D5C4DD2158AF26
type: Structured Name
full name: GTP cyclohydrolase I
short name: GTP-CH-I

folE
type: Gene
locus name: THEYE_A0673

SIP3752FA502C521044
type: Subunit Annotation
comment: Homomer.

SIP36F0FA0A1C634DBC
type: Similarity Annotation
comment: Belongs to the GTP cyclohydrolase I family.

PRO_1000100208
type: Chain Annotation
comment: GTP cyclohydrolase 1
mass: 21521
range: 18636006078427182tt1tt188

18636006078427182tt1
type: Position
type: ExactPosition
position: 1
reference: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK

18636006078427182tt188
type: Position
type: ExactPosition
position: 188
reference: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK

18636006078427182tt76
type: Position
type: ExactPosition
position: 76
reference: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK

18636006078427182tt79
type: Position
type: ExactPosition
position: 79
reference: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK

18636006078427182tt147
type: Position
type: ExactPosition
position: 147
reference: MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK

MFDRKKIEEGVRLILEGIGEDVERPGIKDTPIRIARMFEEIFRGLLPPDEDLLKSIEGETHDEMVLIKDIPFYSVCEHHLLPFFGNAHIAYIPDGRIVGLSELPKALDYLSKRPQVQERLTSQLANLLMEKLKPKGCMVVIEAEHLCMSMRGIKKPDAKTITSAVRGIFRKSQTTRQEALELINRRDK
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 21521

http://purl.uniprot.org/uniprot/B5YJV0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YJV0#attribution-3389E839BCF99834550B5285C976B5BC
manual: true
evidence: ECO_0000255
source: MF_00223

B5YG91
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 73
mnemonic: GLGA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP81117537D441A9FA
alternative name: SIP8BE3046EC2F6BBF9
enzyme: http://purl.uniprot.org/enzyme/2.4.1.21
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP115A10A17CABCACA
annotation: SIP4ECBD8D3285051E0
annotation: SIPC7CAD1BB44457B96
annotation: SIP70DC8CCE699B3F1E
annotation: PRO_1000126110
annotation: SIP00B56DD48CDC98DD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/320
classified with: http://purl.uniprot.org/keywords/328
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0033201
classified with: GO_0004373
classified with: GO_0009011
classified with: GO_0005978
sequence: B5YG91-1
proteome: Chromosome

B5YG91-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

GT5
type: Resource
database: CAZy
comment: Glycosyltransferase Family 5

COG0297
type: Resource
database: eggNOG
comment: Bacteria

cd03791
type: Resource
database: CDD
comment: GT5_Glycogen_synthase_DULL1-like
signature sequence match: CDD cd03791 match 1

http://purl.uniprot.org/gene3d/3.40.50.2000
type: Resource
database: Gene3D
comment: Glycogen Phosphorylase B
signature sequence match: Gene3D 3.40.50.2000 match 1
signature sequence match: Gene3D 3.40.50.2000 match 2

MF_00484
type: Resource
database: HAMAP
comment: Glycogen_synth
signature sequence match: HAMAP MF 00484 match 1

IPR001296
type: Resource
database: InterPro
comment: Glyco_trans_1

IPR011835
type: Resource
database: InterPro
comment: GS/SS

IPR013534
type: Resource
database: InterPro
comment: Starch_synth_cat_dom

PTHR45825
type: Resource
database: PANTHER
comment: GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC
signature sequence match: PANTHER PTHR45825 match 1

PTHR45825:SF11
type: Resource
database: PANTHER
comment: STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC
signature sequence match: PANTHER PTHR45825:SF11 match 1

PF08323
type: Resource
database: Pfam
comment: Glyco_transf_5
signature sequence match: Pfam PF08323 match 1

PF00534
type: Resource
database: Pfam
comment: Glycos_transf_1
signature sequence match: Pfam PF00534 match 1

SSF53756
type: Resource
database: SUPFAM
comment: UDP-Glycosyltransferase/glycogen phosphorylase
signature sequence match: SUPFAM SSF53756 match 1

TIGR02095
type: Resource
database: TIGRFAMs
comment: glgA
signature sequence match: TIGRFAMs TIGR02095 match 1

SIP81117537D441A9FA
type: Structured Name
full name: Glycogen synthase
ec name: 2.4.1.21

SIP8BE3046EC2F6BBF9
type: Structured Name
full name: Starch [bacterial glycogen] synthase

glgA
type: Gene
locus name: THEYE_A1492

SIP115A10A17CABCACA
type: Function Annotation
comment: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

SIP70DC8CCE699B3F1E
type: Similarity Annotation
comment: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

PRO_1000126110
type: Chain Annotation
comment: Glycogen synthase
mass: 56159
range: 18636006026195246tt1tt497

18636006026195246tt1
type: Position
type: ExactPosition
position: 1
reference: B5YG91-1

18636006026195246tt497
type: Position
type: ExactPosition
position: 497
reference: B5YG91-1

18636006026195246tt15
type: Position
type: ExactPosition
position: 15
reference: B5YG91-1

B5YG91-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 56159
value: MKLALVSAEAYPFSKTGGLGDVVGSLFKEFIKAGIDVTLFLPFYKITRDNFSNSVVNAEIVYGAPIGLNTLFGAVRVAKVSVDSDDNLIIEPSKKGNLFFIEHNNFFDRNELYGTNHGEYLDNAERFVFFSRAVLEICKIMNLNFDVIHCHDWHTALIPLYLKTLYRECSCFEKTKTVLTVHNLGYQGIFPREKLELTGFGQEMFHIDGLEFYGMVNFLKGGLFNADIITTVSPTYAKEILTPDYGAGLDGVLRKRKENLVGIINGIDYKIWNPEEDPFIAKKYGLQNINDKQKNKEDLIALAGINSSLQDPIIAFIGRMVYQKGIDIVVDAMPNLIKNGISFIFEGTGESYYEHKIRELQNSYPSKVFAFIGFDEALAHKIYAGADSLLVPSRYEPCGLSQLIAMRYGTIPICRKTGGLSDTVEDKVTGFLFSEYSSSALTHAISRFIEIYNNKQKFLEMIREAMKRDFSWSNSSKKYIELYRGLIGERERKTGTI

http://purl.uniprot.org/uniprot/B5YG91#attribution-172BEF8AEF7E7201DA9924392DEFDFFD
manual: true
evidence: ECO_0000255
source: MF_00484

B5YIR0
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 80
mnemonic: GLGC_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP5E02F283A1605EDA
alternative name: SIP7FD5A96F60B00D11
alternative name: SIP735B781897FCAC7C
enzyme: http://purl.uniprot.org/enzyme/2.7.7.27
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPCC16DF3C01E0EF1B
annotation: SIP1CE9448049A87FBD
annotation: SIP3582668984321497
annotation: SIPAEE6CA67A7EABD06
annotation: SIPC56150B9F74DDD09
annotation: PRO_1000130511
annotation: SIP269F2C828B8FB0ED
annotation: SIPEBA4B0165DCED395
annotation: SIPF43FDDFB56783E2D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/320
classified with: http://purl.uniprot.org/keywords/321
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0008878
classified with: GO_0005978
sequence: B5YIR0-1
proteome: Chromosome

B5YIR0-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0448
type: Resource
database: eggNOG
comment: Bacteria

cd02508
type: Resource
database: CDD
comment: ADP_Glucose_PP
signature sequence match: CDD cd02508 match 1

cd04651
type: Resource
database: CDD
comment: LbH_G1P_AT_C
signature sequence match: CDD cd04651 match 1

http://purl.uniprot.org/gene3d/2.160.10.10
type: Resource
database: Gene3D
comment: Hexapeptide repeat proteins
signature sequence match: Gene3D 2.160.10.10 match 1

MF_00624
type: Resource
database: HAMAP
comment: GlgC
signature sequence match: HAMAP MF 00624 match 1

IPR011831
type: Resource
database: InterPro
comment: ADP-Glc_PPase

IPR005836
type: Resource
database: InterPro
comment: ADP_Glu_pyroP_CS

IPR023049
type: Resource
database: InterPro
comment: GlgC_bac

IPR005835
type: Resource
database: InterPro
comment: NTP_transferase_dom

IPR029044
type: Resource
database: InterPro
comment: Nucleotide-diphossugar_trans

IPR011004
type: Resource
database: InterPro
comment: Trimer_LpxA-like_sf

PTHR43523:SF2
type: Resource
database: PANTHER
comment: GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE
signature sequence match: PANTHER PTHR43523:SF2 match 1

PTHR43523
type: Resource
database: PANTHER
comment: GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED
signature sequence match: PANTHER PTHR43523 match 1

PF00483
type: Resource
database: Pfam
comment: NTP_transferase
signature sequence match: Pfam PF00483 match 1

SSF53448
type: Resource
database: SUPFAM
comment: Nucleotide-diphospho-sugar transferases
signature sequence match: SUPFAM SSF53448 match 1

SSF51161
type: Resource
database: SUPFAM
comment: Trimeric LpxA-like enzymes
signature sequence match: SUPFAM SSF51161 match 1

TIGR02091
type: Resource
database: TIGRFAMs
comment: glgC
signature sequence match: TIGRFAMs TIGR02091 match 1

PS00809
type: Resource
database: PROSITE
comment: ADP_GLC_PYROPHOSPH_2
signature sequence match: PROSITE PS00809 match 1

PS00810
type: Resource
database: PROSITE
comment: ADP_GLC_PYROPHOSPH_3
signature sequence match: PROSITE PS00810 match 1

SIP5E02F283A1605EDA
type: Structured Name
full name: Glucose-1-phosphate adenylyltransferase
ec name: 2.7.7.27

SIP7FD5A96F60B00D11
type: Structured Name
full name: ADP-glucose pyrophosphorylase
short name: ADPGlc PPase

SIP735B781897FCAC7C
type: Structured Name
full name: ADP-glucose synthase

glgC
type: Gene
locus name: THEYE_A0372

SIPCC16DF3C01E0EF1B
type: Function Annotation
comment: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

SIPAEE6CA67A7EABD06
type: Subunit Annotation
comment: Homotetramer.

SIPC56150B9F74DDD09
type: Similarity Annotation
comment: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

PRO_1000130511
type: Chain Annotation
comment: Glucose-1-phosphate adenylyltransferase
mass: 46816
range: 18636006061387822tt1tt411

18636006061387822tt1
type: Position
type: ExactPosition
position: 1
reference: B5YIR0-1

18636006061387822tt411
type: Position
type: ExactPosition
position: 411
reference: B5YIR0-1

18636006061387822tt162
type: Position
type: ExactPosition
position: 162
reference: B5YIR0-1

18636006061387822tt177
type: Position
type: ExactPosition
position: 177
reference: B5YIR0-1

18636006061387822tt178
type: Position
type: ExactPosition
position: 178
reference: B5YIR0-1

18636006061387822tt195
type: Position
type: ExactPosition
position: 195
reference: B5YIR0-1

B5YIR0-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 46816
value: MPKVLAIVLAGGKGERLFPLTSFRSKPSVPFGARYRIVDFVLSNLVNSQIYSIYLLVQYKSQSLIEHIRQNWFFSSVGSDHFVTVVPPQMRMGPEWFQGTADAVFQNIGLIKEHNPDIVLIFGADHIYRMDIRQMIKFHIENNAHVTVAARPVALKHASSFGVIITDPDHRIAGFQEKPKDPIPMPDNPDMAYVSMGNYIFNADILIDALVRAEKKKQHDFGAHVIPDLVGRKCKVYAYDFAKNEIPGIKSYEERGYWRDVGTISAYFDAHMDMLGEKPIFEIYNKMWPIHPARYEGPPVKILDGEIKNSIIAEGALIYGGKIENSFIRSGSIIEKDVEIKDSLIMDDVIIKRNSKLYRVIVDKKNVVYEGEKIGFSAEQDRFRCYIDSSGICILPRAARYNDWIKEINHA

http://purl.uniprot.org/uniprot/B5YIR0#attribution-29E20A4965EA5D2B682789D8248FF830
manual: true
evidence: ECO_0000255
source: MF_00624

B5YGX0
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 76
mnemonic: GLMM_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIP4599C31D49F2F569
enzyme: http://purl.uniprot.org/enzyme/5.4.2.10
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP67DA08DCD56C9C70
annotation: SIP1BA57308C798E88D
annotation: SIP1ED196F6E1CB9F95
annotation: SIP1B16268177D33E86
annotation: SIP6029BFE91FE0AE20
annotation: PRO_1000185392
annotation: SIP6DB49F28433072AD
annotation: SIPF0066EB30F5106C8
annotation: SIPAE4FC6E72765CCED
annotation: SIP23DB6431B84A7BB6
annotation: SIP894E9515AB8133E4
annotation: SIP936394E0F5D41030
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0000287
classified with: GO_0008966
classified with: GO_0004615
classified with: GO_0005975
classified with: GO_0009252
classified with: GO_0006048
sequence: B5YGX0-1
proteome: Chromosome

B5YGX0-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1109
type: Resource
database: eggNOG
comment: Bacteria

cd05802
type: Resource
database: CDD
comment: GlmM
signature sequence match: CDD cd05802 match 1

http://purl.uniprot.org/gene3d/3.40.120.10
type: Resource
database: Gene3D
comment: Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3
signature sequence match: Gene3D 3.40.120.10 match 1
signature sequence match: Gene3D 3.40.120.10 match 2
signature sequence match: Gene3D 3.40.120.10 match 3

http://purl.uniprot.org/gene3d/3.30.310.50
type: Resource
database: Gene3D
comment: Alpha-D-phosphohexomutase, C-terminal domain
signature sequence match: Gene3D 3.30.310.50 match 1

MF 01554 B
type: Resource
database: HAMAP
comment: GlmM_B
signature sequence match: HAMAP MF 01554 B match 1

IPR005844
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-I

IPR016055
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-I/II/III

IPR005845
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-II

IPR005846
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-III

IPR005843
type: Resource
database: InterPro
comment: A-D-PHexomutase_C

IPR036900
type: Resource
database: InterPro
comment: A-D-PHexomutase_C_sf

IPR016066
type: Resource
database: InterPro
comment: A-D-PHexomutase_CS

IPR005841
type: Resource
database: InterPro
comment: Alpha-D-phosphohexomutase_SF

IPR006352
type: Resource
database: InterPro
comment: GlmM_bact

PTHR42946:SF1
type: Resource
database: PANTHER
comment: PHOSPHOGLUCOSAMINE MUTASE FAMILY PROTEIN
signature sequence match: PANTHER PTHR42946:SF1 match 1

PTHR42946
type: Resource
database: PANTHER
comment: PHOSPHOHEXOSE MUTASE
signature sequence match: PANTHER PTHR42946 match 1

PF02878
type: Resource
database: Pfam
comment: PGM_PMM_I
signature sequence match: Pfam PF02878 match 1

PF02879
type: Resource
database: Pfam
comment: PGM_PMM_II
signature sequence match: Pfam PF02879 match 1

PF02880
type: Resource
database: Pfam
comment: PGM_PMM_III
signature sequence match: Pfam PF02880 match 1

PF00408
type: Resource
database: Pfam
comment: PGM_PMM_IV
signature sequence match: Pfam PF00408 match 1

PR00509
type: Resource
database: PRINTS
comment: PGMPMM

SSF55957
type: Resource
database: SUPFAM
comment: Phosphoglucomutase, C-terminal domain
signature sequence match: SUPFAM SSF55957 match 1

SSF53738
type: Resource
database: SUPFAM
comment: Phosphoglucomutase, first 3 domains
signature sequence match: SUPFAM SSF53738 match 1
signature sequence match: SUPFAM SSF53738 match 2
signature sequence match: SUPFAM SSF53738 match 3

TIGR01455
type: Resource
database: TIGRFAMs
comment: glmM
signature sequence match: TIGRFAMs TIGR01455 match 1

PS00710
type: Resource
database: PROSITE
comment: PGM_PMM
signature sequence match: PROSITE PS00710 match 1

SIP4599C31D49F2F569
type: Structured Name
full name: Phosphoglucosamine mutase
ec name: 5.4.2.10

glmM
type: Gene
locus name: THEYE_A0046

SIP67DA08DCD56C9C70
type: Function Annotation
comment: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

SIP1ED196F6E1CB9F95
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIP1B16268177D33E86
type: PTM Annotation
comment: Activated by phosphorylation.

SIP6029BFE91FE0AE20
type: Similarity Annotation
comment: Belongs to the phosphohexose mutase family.

PRO_1000185392
type: Chain Annotation
comment: Phosphoglucosamine mutase
mass: 49962
range: 18636006028226606tt1tt451

18636006028226606tt1
type: Position
type: ExactPosition
position: 1
reference: B5YGX0-1

18636006028226606tt451
type: Position
type: ExactPosition
position: 451
reference: B5YGX0-1

SIP6DB49F28433072AD
type: Active Site Annotation
comment: Phosphoserine intermediate
range: 18636006028226606tt101tt101

18636006028226606tt101
type: Position
type: ExactPosition
position: 101
reference: B5YGX0-1

SIPF0066EB30F5106C8
type: Binding Site Annotation
comment: via phosphate group
ligand: SIPF40628EA7D6FABAA
range: 18636006028226606tt101tt101

18636006028226606tt243
type: Position
type: ExactPosition
position: 243
reference: B5YGX0-1

18636006028226606tt245
type: Position
type: ExactPosition
position: 245
reference: B5YGX0-1

18636006028226606tt247
type: Position
type: ExactPosition
position: 247
reference: B5YGX0-1

SIP936394E0F5D41030
type: Modified Residue Annotation
comment: Phosphoserine
range: 18636006028226606tt101tt101

B5YGX0-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 49962
value: MRIFGTDGIRGTINNYPMTPEVCLRAGMALCFLLKKRLPHKPKILIGKDTRISGYVIESALTSGITSMGGDVYLVGPIPTPAVAFLVKSMRVDAGIVISASHNPFSDNGIKIFSNDGFKLTEELENDIEKLINDKDFPAIRPSARELGKAYRIEDAQGRYIEFIKSTLPKDSNLEGLKVAIDPANGAAYKITPTLFHELGAEVITINDKPDGVNINKECGALYPESLIKIVKETQAHFGVAHDGDADRTILVDEKGNIVDGDFILTILAEELKKERKLKKNTVVATIMTNMGVENYLKNAGIKMIRTKVGDKYVVEEMLKGGYNLGGEQSGHIICMDYTNTGDGPITAVQMAYIIKKNQFYLSELIKNIPRYPQALKNIKIPEKLPKDEVKNVIKKLSQKASTLEKNMRGRIIIRPSGTEPKIRIMVEDENPERLKQVLDELEAVANMMLS

http://purl.uniprot.org/uniprot/B5YGX0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YGX0#attribution-C93393D63E25D74B141B8CB43ED1CFC9
manual: true
evidence: ECO_0000255
source: MF_01554

B5YHS4
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-02-22
version: 79
mnemonic: GLMU_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPCA8A86852D5E53A7
domain: SIP5A073372A6624A0C
domain: SIPC29F6BF5ECAC7A4F
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPC45F1159DDAD7E0A
annotation: SIPFBBC07314E7A3B31
annotation: SIP52FF82662AC2C5BE
annotation: SIPBB54AA532C1EC458
annotation: SIPD8E03972E5FB18B9
annotation: SIPE93195EA59D2410A
annotation: SIP75067CD18ECCBE21
annotation: SIPA042890CCBC61220
annotation: SIPFF017200F387B43F
annotation: SIP2C281772E7AFDD66
annotation: SIPAF9C5BE6C50FA38F
annotation: PRO_1000186507
annotation: SIP36190110B4E7FE9C
annotation: SIP2E36BE2F61B177D4
annotation: SIP5A32407BA774B348
annotation: SIPA7B9452E88953B5D
annotation: SIP5346F79EBCF89AAE
annotation: SIP5A36814BE0192451
annotation: SIP1E37F072A394C49E
annotation: SIP8B5BC91A26843736
annotation: SIP477059FA7CF5B3B0
annotation: SIP00429CE028E77E74
annotation: SIP19FF8B9389F04B04
annotation: SIP5BBDE5A7E567B4AD
annotation: SIP6E6A0361A4C56FF0
annotation: SIP3F6D1B8005EF58AB
annotation: SIPCA7FC5F7C017DD1E
annotation: SIP2474F4BC89E2B810
annotation: SIP1F2C8B323083B5DE
annotation: SIP092C3443D8FDD05B
annotation: SIP1D09C97BBFB82C99
annotation: SIP0D04EB3763521846
annotation: SIP904BEF985A6EF588
annotation: SIPFD9232DD9524B6F0
annotation: SIPD087ED289626E385
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/12
classified with: http://purl.uniprot.org/keywords/961
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/511
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/573
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: GO_0005737
classified with: GO_0019134
classified with: GO_0000287
classified with: GO_0003977
classified with: GO_0000902
classified with: GO_0071555
classified with: GO_0009245
classified with: GO_0009252
classified with: GO_0008360
classified with: GO_0006048
sequence: B5YHS4-1
proteome: Chromosome

B5YHS4-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG1207
type: Resource
database: eggNOG
comment: Bacteria

cd02540
type: Resource
database: CDD
comment: GT2_GlmU_N_bac
signature sequence match: CDD cd02540 match 1

cd03353
type: Resource
database: CDD
comment: LbH_GlmU_C
signature sequence match: CDD cd03353 match 1

MF_01631
type: Resource
database: HAMAP
comment: GlmU
signature sequence match: HAMAP MF 01631 match 1

IPR005882
type: Resource
database: InterPro
comment: Bifunctional_GlmU

IPR038009
type: Resource
database: InterPro
comment: GlmU_C_LbH

IPR001451
type: Resource
database: InterPro
comment: Hexapep

IPR025877
type: Resource
database: InterPro
comment: MobA-like_NTP_Trfase

PTHR43584:SF3
type: Resource
database: PANTHER
comment: BIFUNCTIONAL PROTEIN GLMU
signature sequence match: PANTHER PTHR43584:SF3 match 1

PTHR43584
type: Resource
database: PANTHER
comment: NUCLEOTIDYL TRANSFERASE
signature sequence match: PANTHER PTHR43584 match 1

PF00132
type: Resource
database: Pfam
comment: Hexapep
signature sequence match: Pfam PF00132 match 1
signature sequence match: Pfam PF00132 match 2
signature sequence match: Pfam PF00132 match 3

PF12804
type: Resource
database: Pfam
comment: NTP_transf_3
signature sequence match: Pfam PF12804 match 1

TIGR01173
type: Resource
database: TIGRFAMs
comment: glmU
signature sequence match: TIGRFAMs TIGR01173 match 1

SIPCA8A86852D5E53A7
type: Structured Name
full name: Bifunctional protein GlmU

SIPC951C80C0C95FA55
type: Structured Name
full name: UDP-N-acetylglucosamine pyrophosphorylase
ec name: 2.7.7.23

SIPCEDAB4ED360D081A
type: Structured Name
full name: N-acetylglucosamine-1-phosphate uridyltransferase

SIP86B4ACCCB7F209A0
type: Structured Name
full name: Glucosamine-1-phosphate N-acetyltransferase
ec name: 2.3.1.157

glmU
type: Gene
locus name: THEYE_A1870

SIPC45F1159DDAD7E0A
type: Function Annotation
comment: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.

SIPBB54AA532C1EC458
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIPA042890CCBC61220
type: Subunit Annotation
comment: Homotrimer.

SIP2C281772E7AFDD66
type: Similarity Annotation
comment: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

SIPAF9C5BE6C50FA38F
type: Similarity Annotation
comment: In the C-terminal section; belongs to the transferase hexapeptide repeat family.

PRO_1000186507
type: Chain Annotation
comment: Bifunctional protein GlmU
mass: 50222
range: 18636006044677166tt1tt452

18636006044677166tt1
type: Position
type: ExactPosition
position: 1
reference: B5YHS4-1

18636006044677166tt452
type: Position
type: ExactPosition
position: 452
reference: B5YHS4-1

SIP36190110B4E7FE9C
type: Region Annotation
comment: Pyrophosphorylase
range: 18636006044677166tt1tt225

18636006044677166tt225
type: Position
type: ExactPosition
position: 225
reference: B5YHS4-1

SIP2E36BE2F61B177D4
type: Region Annotation
comment: Linker
range: 18636006044677166tt226tt246

18636006044677166tt226
type: Position
type: ExactPosition
position: 226
reference: B5YHS4-1

18636006044677166tt246
type: Position
type: ExactPosition
position: 246
reference: B5YHS4-1

SIP5A32407BA774B348
type: Region Annotation
comment: N-acetyltransferase
range: 18636006044677166tt247tt452

18636006044677166tt247
type: Position
type: ExactPosition
position: 247
reference: B5YHS4-1

SIPA7B9452E88953B5D
type: Active Site Annotation
comment: Proton acceptor
range: 18636006044677166tt359tt359

18636006044677166tt359
type: Position
type: ExactPosition
position: 359
reference: B5YHS4-1

18636006044677166tt6
type: Position
type: ExactPosition
position: 6
reference: B5YHS4-1

18636006044677166tt9
type: Position
type: ExactPosition
position: 9
reference: B5YHS4-1

18636006044677166tt20
type: Position
type: ExactPosition
position: 20
reference: B5YHS4-1

18636006044677166tt71
type: Position
type: ExactPosition
position: 71
reference: B5YHS4-1

18636006044677166tt76
type: Position
type: ExactPosition
position: 76
reference: B5YHS4-1

18636006044677166tt77
type: Position
type: ExactPosition
position: 77
reference: B5YHS4-1

18636006044677166tt99
type: Position
type: ExactPosition
position: 99
reference: B5YHS4-1

18636006044677166tt136
type: Position
type: ExactPosition
position: 136
reference: B5YHS4-1

18636006044677166tt151
type: Position
type: ExactPosition
position: 151
reference: B5YHS4-1

18636006044677166tt166
type: Position
type: ExactPosition
position: 166
reference: B5YHS4-1

18636006044677166tt223
type: Position
type: ExactPosition
position: 223
reference: B5YHS4-1

18636006044677166tt329
type: Position
type: ExactPosition
position: 329
reference: B5YHS4-1

18636006044677166tt347
type: Position
type: ExactPosition
position: 347
reference: B5YHS4-1

18636006044677166tt362
type: Position
type: ExactPosition
position: 362
reference: B5YHS4-1

18636006044677166tt373
type: Position
type: ExactPosition
position: 373
reference: B5YHS4-1

18636006044677166tt376
type: Position
type: ExactPosition
position: 376
reference: B5YHS4-1

18636006044677166tt382
type: Position
type: ExactPosition
position: 382
reference: B5YHS4-1

18636006044677166tt383
type: Position
type: ExactPosition
position: 383
reference: B5YHS4-1

18636006044677166tt401
type: Position
type: ExactPosition
position: 401
reference: B5YHS4-1

18636006044677166tt419
type: Position
type: ExactPosition
position: 419
reference: B5YHS4-1

18636006044677166tt436
type: Position
type: ExactPosition
position: 436
reference: B5YHS4-1

B5YHS4-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 50222
value: MDVVILAAGLGTRMKSSKPKVLHRILEKPIIDYVIDCAKSLNPFNSFVVINPSLKEVAEHLEKYNIKIVFQDEPKGTAHALLSALPYLSSDKILILNGDTPLLRKETLDSFIELFNKNGLDMALLSFYPQREHSYGRILRDGEQKIKKIVEITDFKDELMLSSEANSGIYILKREVAELVKEIKQNPNKGEFYLTDIVEIAVNKGFNIEAYPLAEENELIGINTRAELSLAMRYLRDRIVKGWMEKGITFYDPALVWISPSVTIGQDTIIYPNVFLEGDTKIGQNCLICQGVRIKNSIIEDNVQINDCTVIENSHIKSASKIGPFAHLRPDSIIGKGCRIGNFVEVKNSTIGDGTKAAHLSYIGDSEIGNNVNIGAGTITCNYDGQKKHKTIIEDNVFIGSDTQLVAPVKICKGAYIGAGSTITKEVPEDSLAISRTPQKNILGWAKKKRKQ

http://purl.uniprot.org/uniprot/B5YHS4#attribution-050D2B8762FDB859BFC3E638879F5B12
manual: true
evidence: ECO_0000255
source: MF_01631

B5YFZ0
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-02-22
version: 81
mnemonic: GLYA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPA8BEDF791B077162
enzyme: http://purl.uniprot.org/enzyme/2.1.2.1
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIPD701782BC7C561BE
annotation: SIP8CD7174B119AD51F
annotation: SIP633A1AE4572A8DFA
annotation: SIP26B8911CB09C8DA5
annotation: SIPA6785F9E7CF4B363
annotation: SIPB63E1AD1E122C5F6
annotation: SIP653EFB7879225C87
annotation: SIPA734758E8BA3F59C
annotation: PRO_0000369960
annotation: SIP60CC49982431AF40
annotation: SIP9D1BA688B573BFD8
annotation: SIPD1BB83C160C6D718
annotation: SIP114F7F06508A1C06
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/28
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/554
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0005829
classified with: GO_0004372
classified with: GO_0030170
classified with: GO_0070905
classified with: GO_0008270
classified with: GO_0046655
classified with: GO_0019264
classified with: GO_0006565
classified with: GO_0006730
classified with: GO_0035999
classified with: GO_0046653
sequence: B5YFZ0-1
proteome: Chromosome

B5YFZ0-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0112
type: Resource
database: eggNOG
comment: Bacteria

cd00378
type: Resource
database: CDD
comment: SHMT
signature sequence match: CDD cd00378 match 1

MF_00051
type: Resource
database: HAMAP
comment: SHMT
signature sequence match: HAMAP MF 00051 match 1

IPR001085
type: Resource
database: InterPro
comment: Ser_HO-MeTrfase

IPR019798
type: Resource
database: InterPro
comment: Ser_HO-MeTrfase_PLP_BS

IPR039429
type: Resource
database: InterPro
comment: SHMT-like_dom

PTHR11680
type: Resource
database: PANTHER
comment: SERINE HYDROXYMETHYLTRANSFERASE
signature sequence match: PANTHER PTHR11680 match 1

PTHR11680:SF28
type: Resource
database: PANTHER
comment: SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11680:SF28 match 1

PF00464
type: Resource
database: Pfam
comment: SHMT
signature sequence match: Pfam PF00464 match 1

PIRSF000412
type: Resource
database: PIRSF
comment: SHMT
signature sequence match: PIRSF PIRSF000412 match 1

PS00096
type: Resource
database: PROSITE
comment: SHMT
signature sequence match: PROSITE PS00096 match 1

SIPA8BEDF791B077162
type: Structured Name
full name: Serine hydroxymethyltransferase
short name: SHMT
short name: Serine methylase
ec name: 2.1.2.1

glyA
type: Gene
locus name: THEYE_A1387

SIPD701782BC7C561BE
type: Function Annotation
comment: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.

SIPB63E1AD1E122C5F6
type: Subunit Annotation
comment: Homodimer.

SIPA734758E8BA3F59C
type: Similarity Annotation
comment: Belongs to the SHMT family.

PRO_0000369960
type: Chain Annotation
comment: Serine hydroxymethyltransferase
mass: 45673
range: 18636006011580462tt1tt412

18636006011580462tt1
type: Position
type: ExactPosition
position: 1
reference: B5YFZ0-1

18636006011580462tt412
type: Position
type: ExactPosition
position: 412
reference: B5YFZ0-1

18636006011580462tt119
type: Position
type: ExactPosition
position: 119
reference: B5YFZ0-1

18636006011580462tt123
type: Position
type: ExactPosition
position: 123
reference: B5YFZ0-1

18636006011580462tt125
type: Position
type: ExactPosition
position: 125
reference: B5YFZ0-1

SIPD1BB83C160C6D718
type: Site Annotation
comment: Plays an important role in substrate specificity
range: 18636006011580462tt227tt227

18636006011580462tt227
type: Position
type: ExactPosition
position: 227
reference: B5YFZ0-1

SIP114F7F06508A1C06
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18636006011580462tt228tt228

18636006011580462tt228
type: Position
type: ExactPosition
position: 228
reference: B5YFZ0-1

B5YFZ0-1
type: Simple Sequence
modified: 2008-11-25
version: 1
mass: 45673
value: MKMKSLREVDAEIYSLILQEKKRETNKILMIASENYASRAVMEAQGSLFTNKYAEGYPGRRYYGGCEYADEVERLAQERAKQLFNVEHVNVQPHSGTQANMAVYFAMLQPGDTIMGMSLTHGGHLSHGSPVNFTGKLYKTVFYGVNKETGYIDMDEVRRLAQEHKPKIIITGASAYPRTIDFKAFSEIAKEVGAYLMADIAHIAGLIATSMHPSPVPYSDFITTTTHKTLRGPRGGVVMCKAQYAKAIDKTVFPGIQGGPLVHVIAAKAVAFKEALSEDFKEYQKKVIKNAKTLAEALKKKGFKLVSDGTDNHLMLVDLTNFNITGKEAEEALDKAGITVNKNTIPFDTKPPTVTSGIRIGTPSVTTRGMGEEEMEKIAEIIERVIKNISNDSVIKDMQKKVQELCKKFPIY

http://purl.uniprot.org/uniprot/B5YFZ0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/B5YFZ0#attribution-3599E19C8BC546E40420244F25405B1D
manual: true
evidence: ECO_0000255
source: MF_00051

B5YJT7
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-02-22
version: 69
mnemonic: GMHA_THEYD
citation: SIPE9FD0B7DB3E0BCE1
recommended name: SIPBCD0C22383E0EE7C
alternative name: SIPAE919FD756C5174F
enzyme: http://purl.uniprot.org/enzyme/5.3.1.28
organism: http://purl.uniprot.org/taxonomy/289376
annotation: SIP3C33989C33020F73
annotation: SIP33281A63C843F5C8
annotation: SIPF882649D42BADB91
annotation: SIP2B3D709033DD73C7
annotation: SIP52344F70F077AACE
annotation: SIPBD56ED3C75F03A81
annotation: SIP1DB30009B6A053EC
annotation: PRO_1000092295
annotation: SIP0C49F775B38D1AB0
annotation: SIP93D6E9148561BA01
annotation: SIPE0DCA2786BB57E39
annotation: SIP6451CA40E145C49A
annotation: SIP9BF32A3CFE152684
annotation: SIPC3F8EEC196982782
annotation: SIP67747CBE10651EF6
annotation: SIPBD58DCEE2D94FBBE
annotation: SIPCBDE6E44B55688B4
annotation: SIP5F5FE7F4E726AA57
annotation: SIP455A30CE4803106D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/119
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0097367
classified with: GO_0008968
classified with: GO_0008270
classified with: GO_0005975
classified with: GO_2001061
sequence: B5YJT7-1
proteome: Chromosome

B5YJT7-citation-SIPE9FD0B7DB3E0BCE1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 51303 / DSM 11347 / YP87
type: Strain

COG0279
type: Resource
database: eggNOG
comment: Bacteria

cd05006
type: Resource
database: CDD
comment: SIS_GmhA
signature sequence match: CDD cd05006 match 1

MF_00067
type: Resource
database: HAMAP
comment: GmhA
signature sequence match: HAMAP MF 00067 match 1

IPR035461
type: Resource
database: InterPro
comment: GmhA/DiaA

IPR004515
type: Resource
database: InterPro
comment: Phosphoheptose_Isoase

IPR001347
type: Resource
database: InterPro
comment: SIS_dom

IPR046348
type: Resource
database: InterPro
comment: SIS_dom_sf

PTHR30390:SF6
type: Resource
database: PANTHER
comment: DNAA INITIATOR-ASSOCIATING PROTEIN DIAA
signature sequence match: PANTHER PTHR30390:SF6 match 1

PTHR30390
type: Resource
database: PANTHER
comment: SEDOHEPTULOSE 7-PHOSPHATE ISOMERASE / DNAA INITIATOR-ASSOCIATING FACTOR FOR REPLICATION INITIATION
signature sequence match: PANTHER PTHR30390 match 1

PF13580
type: Resource
database: Pfam
comment: SIS_2
signature sequence match: Pfam PF13580 match 1

SSF53697
type: Resource
database: SUPFAM
comment: SIS domain
signature sequence match: SUPFAM SSF53697 match 1

PS51464
type: Resource
database: PROSITE
comment: SIS
signature sequence match: PROSITE PS51464 match 1

SIPBCD0C22383E0EE7C
type: Structured Name
full name: Phosphoheptose isomerase
ec name: 5.3.1.28

SIPAE919FD756C5174F
type: Structured Name
full name: Sedoheptulose 7-phosphate isomerase

gmhA
type: Gene
locus name: THEYE_A0660

SIP3C33989C33020F73
type: Function Annotation
comment: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.