B7JA39
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 79
mnemonic: ACCA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPD345ED6FED4C7897
enzyme: http://purl.uniprot.org/enzyme/2.1.3.15
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP2938FCFE5C382188
annotation: SIP67ABD6D2AC86BE7D
annotation: SIPC4D16D0DB9579AA5
annotation: SIP903A75D2D0A4FEDB
annotation: SIP2542670BE0E0607D
annotation: SIPE551F50DEBFF1926
annotation: PRO_1000148726
annotation: SIP1F2690830059F1C0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0009317
classified with: GO_0003989
classified with: GO_0005524
classified with: GO_0016743
classified with: GO_0006633
classified with: GO_2001295
sequence: B7JA39-1
proteome: Chromosome

B7JA39-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0825
type: Resource
database: eggNOG
comment: Bacteria

MF_00823
type: Resource
database: HAMAP
comment: AcetylCoA_CT_alpha
signature sequence match: HAMAP MF 00823 match 1

IPR001095
type: Resource
database: InterPro
comment: Acetyl_CoA_COase_a_su

IPR029045
type: Resource
database: InterPro
comment: ClpP/crotonase-like_dom_sf

IPR011763
type: Resource
database: InterPro
comment: COA_CT_C

PTHR42853
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA
signature sequence match: PANTHER PTHR42853 match 1

PTHR42853:SF3
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA, CHLOROPLASTIC
signature sequence match: PANTHER PTHR42853:SF3 match 1

PF03255
type: Resource
database: Pfam
comment: ACCA
signature sequence match: Pfam PF03255 match 1

PR01069
type: Resource
database: PRINTS
comment: ACCCTRFRASEA

SSF52096
type: Resource
database: SUPFAM
comment: ClpP/crotonase
signature sequence match: SUPFAM SSF52096 match 1

TIGR00513
type: Resource
database: TIGRFAMs
comment: accA
signature sequence match: TIGRFAMs TIGR00513 match 1

PS50989
type: Resource
database: PROSITE
comment: COA_CT_CTER
signature sequence match: PROSITE PS50989 match 1

SIPD345ED6FED4C7897
type: Structured Name
full name: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
short name: ACCase subunit alpha
short name: Acetyl-CoA carboxylase carboxyltransferase subunit alpha
ec name: 2.1.3.15

accA
type: Gene
locus name: AFE_1462

SIP2938FCFE5C382188
type: Function Annotation
comment: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.

SIP903A75D2D0A4FEDB
type: Subunit Annotation
comment: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).

SIPE551F50DEBFF1926
type: Similarity Annotation
comment: Belongs to the AccA family.

PRO_1000148726
type: Chain Annotation
comment: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
mass: 34693
range: 18638140523886894tt1tt316

18638140523886894tt1
type: Position
type: ExactPosition
position: 1
reference: B7JA39-1

18638140523886894tt316
type: Position
type: ExactPosition
position: 316
reference: B7JA39-1

SIP1F2690830059F1C0
type: Domain Extent Annotation
comment: CoA carboxyltransferase C-terminal
range: 18638140523886894tt40tt290

18638140523886894tt40
type: Position
type: ExactPosition
position: 40
reference: B7JA39-1

18638140523886894tt290
type: Position
type: ExactPosition
position: 290
reference: B7JA39-1

B7JA39-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 34693
value: MKISYLDFEQSVAELDAKVEELHALNQPGIADDISRLEVKARKELQRIYSKLGAWQTVQVARHPQRPYTMDYVQALFTEVQVLAGDRAFADDQAIIGGLARFNGQPIVWMGHQKGRDTKEKIQRNFGMPRPEGYRKALRLLRLAERFALPVFTFIDTPGAYPGIGAEERGQSEAIARNLAVMSDLAVPIICTVIGEGGSGGALAIGVGDRMLMLEYGVYSVISPEGCASILWKNAAMAAEAAETLGITARRLQGMGLVDEVLAEPLGGAHRDPEAVFALARERFAHHLQELQAMDTSKLLTTRYERLMHYGVVGAA

http://purl.uniprot.org/uniprot/B7JA39#attribution-59F6F4DF8DA7A0D31AA2B64E6869E9D5
manual: true
evidence: ECO_0000255
source: MF_00823

http://purl.uniprot.org/uniprot/B7JA39#attribution-71DD31C3EAE9838607F06234F6539BBA
manual: true
evidence: ECO_0000255
source: PRU01137

B5EQR6
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 82
mnemonic: ACCA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPD345ED6FED4C7897
enzyme: http://purl.uniprot.org/enzyme/2.1.3.15
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP24FDE834B055B3EF
annotation: SIP648A307D0FC3B32E
annotation: SIP5402385ED9409444
annotation: SIPEFDB62935B62C2B2
annotation: SIP49039E163C59C1EC
annotation: SIP51EFC83531C027E0
annotation: PRO_1000148727
annotation: SIP6D06CC96116E006F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0009317
classified with: GO_0003989
classified with: GO_0005524
classified with: GO_0016743
classified with: GO_0006633
classified with: GO_2001295
sequence: B5EQR6-1

SIP952ED53E42E68AC1
type: Submission Citation
title: Complete sequence of Acidithiobacillus ferrooxidans ATCC 53993.
author: Lucas S.
author: Copeland A.
author: Lapidus A.
author: Glavina del Rio T.
author: Dalin E.
author: Tice H.
author: Bruce D.
author: Goodwin L.
author: Pitluck S.
author: Sims D.
author: Brettin T.
author: Detter J.C.
author: Han C.
author: Kuske C.R.
author: Larimer F.
author: Land M.
author: Hauser L.
author: Kyrpides N.
author: Lykidis A.
author: Borole A.P.
date: 2008-08
submitted to: EMBL/GenBank/DDBJ

B5EQR6-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPD345ED6FED4C7897
type: Structured Name
full name: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
short name: ACCase subunit alpha
short name: Acetyl-CoA carboxylase carboxyltransferase subunit alpha
ec name: 2.1.3.15

accA
type: Gene
locus name: Lferr_1178

SIP24FDE834B055B3EF
type: Function Annotation
comment: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.

SIPEFDB62935B62C2B2
type: Subunit Annotation
comment: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).

SIP51EFC83531C027E0
type: Similarity Annotation
comment: Belongs to the AccA family.

PRO_1000148727
type: Chain Annotation
comment: Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
mass: 34693
range: 18635920296261166tt1tt316

18635920296261166tt1
type: Position
type: ExactPosition
position: 1
reference: B5EQR6-1

18635920296261166tt316
type: Position
type: ExactPosition
position: 316
reference: B5EQR6-1

SIP6D06CC96116E006F
type: Domain Extent Annotation
comment: CoA carboxyltransferase C-terminal
range: 18635920296261166tt40tt290

18635920296261166tt40
type: Position
type: ExactPosition
position: 40
reference: B5EQR6-1

18635920296261166tt290
type: Position
type: ExactPosition
position: 290
reference: B5EQR6-1

B5EQR6-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 34693
value: MKISYLDFEQSVAELDAKVEELHALNQPGIADDISRLEVKARKELQRIYSKLGAWQTVQVARHPQRPYTMDYVQALFTEVQVLAGDRAFADDQAIIGGLARFNGQPIVWMGHQKGRDTKEKIQRNFGMPRPEGYRKALRLLRLAERFALPVFTFIDTPGAYPGIGAEERGQSEAIARNLAVMSDLAVPIICTVIGEGGSGGALAIGVGDRMLMLEYGVYSVISPEGCASILWKNAAMAAEAAETLGITARRLQGMGLVDEVLAEPLGGAHRDPEAVFALARERFAHHLQELQAMDTSKLLTTRYERLMHYGVVGAA

http://purl.uniprot.org/uniprot/B5EQR6#attribution-59F6F4DF8DA7A0D31AA2B64E6869E9D5
manual: true
evidence: ECO_0000255
source: MF_00823

http://purl.uniprot.org/uniprot/B5EQR6#attribution-71DD31C3EAE9838607F06234F6539BBA
manual: true
evidence: ECO_0000255
source: PRU01137

B7J9K5
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 69
mnemonic: ACPS_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP2BEBC682D9C5D011
alternative name: SIP479C3A2215184A35
enzyme: http://purl.uniprot.org/enzyme/2.7.8.7
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPA951F1868F5E0CE2
annotation: SIP8DB559FD46697C78
annotation: SIP186214BE659FBD25
annotation: SIP6CB8B2B30281C8DD
annotation: SIPA6C2EC45642CA4BC
annotation: PRO_1000117339
annotation: SIPF926DB34779D3512
annotation: SIPB9E19D0E4EEF5560
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0008897
classified with: GO_0000287
classified with: GO_0006633
sequence: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG
proteome: Chromosome

B7J9K5-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0736
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.90.470.20
type: Resource
database: Gene3D
comment: 4'-phosphopantetheinyl transferase domain
signature sequence match: Gene3D 3.90.470.20 match 1

MF_00101
type: Resource
database: HAMAP
comment: AcpS
signature sequence match: HAMAP MF 00101 match 1

IPR008278
type: Resource
database: InterPro
comment: 4-PPantetheinyl_Trfase_dom

IPR037143
type: Resource
database: InterPro
comment: 4-PPantetheinyl_Trfase_dom_sf

IPR002582
type: Resource
database: InterPro
comment: ACPS

IPR004568
type: Resource
database: InterPro
comment: Ppantetheine-prot_Trfase_dom

PF01648
type: Resource
database: Pfam
comment: ACPS
signature sequence match: Pfam PF01648 match 1

SSF56214
type: Resource
database: SUPFAM
comment: 4'-phosphopantetheinyl transferase
signature sequence match: SUPFAM SSF56214 match 1

TIGR00516
type: Resource
database: TIGRFAMs
comment: acpS
signature sequence match: TIGRFAMs TIGR00516 match 1

TIGR00556
type: Resource
database: TIGRFAMs
comment: pantethn_trn
signature sequence match: TIGRFAMs TIGR00556 match 1

SIP2BEBC682D9C5D011
type: Structured Name
full name: Holo-[acyl-carrier-protein] synthase
short name: Holo-ACP synthase
ec name: 2.7.8.7

SIP479C3A2215184A35
type: Structured Name
full name: 4'-phosphopantetheinyl transferase AcpS

acpS
type: Gene
locus name: AFE_1404

SIPA951F1868F5E0CE2
type: Function Annotation
comment: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

SIPA6C2EC45642CA4BC
type: Similarity Annotation
comment: Belongs to the P-Pant transferase superfamily. AcpS family.

PRO_1000117339
type: Chain Annotation
comment: Holo-[acyl-carrier-protein] synthase
mass: 13895
range: 18638140391241006tt1tt129

18638140391241006tt1
type: Position
type: ExactPosition
position: 1
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18638140391241006tt129
type: Position
type: ExactPosition
position: 129
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18638140391241006tt8
type: Position
type: ExactPosition
position: 8
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18638140391241006tt58
type: Position
type: ExactPosition
position: 58
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 13895

http://purl.uniprot.org/uniprot/B7J9K5#attribution-1F5F5386E209DFCC3422387253639116
manual: true
evidence: ECO_0000255
source: MF_00101

B5EQL7
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 74
mnemonic: ACPS_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP2BEBC682D9C5D011
alternative name: SIP479C3A2215184A35
enzyme: http://purl.uniprot.org/enzyme/2.7.8.7
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP1997091E66E1CB37
annotation: SIP80DE354388B09CFA
annotation: SIP1B91C168EEDE0771
annotation: SIPC18027CB331BFC21
annotation: SIP62DA6527C8655FD4
annotation: PRO_1000093850
annotation: SIPB724604FD0B570E3
annotation: SIP73769540F9510D1A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0008897
classified with: GO_0000287
classified with: GO_0006633
sequence: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

B5EQL7-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP2BEBC682D9C5D011
type: Structured Name
full name: Holo-[acyl-carrier-protein] synthase
short name: Holo-ACP synthase
ec name: 2.7.8.7

SIP479C3A2215184A35
type: Structured Name
full name: 4'-phosphopantetheinyl transferase AcpS

acpS
type: Gene
locus name: Lferr_1125

SIP1997091E66E1CB37
type: Function Annotation
comment: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

SIP62DA6527C8655FD4
type: Similarity Annotation
comment: Belongs to the P-Pant transferase superfamily. AcpS family.

PRO_1000093850
type: Chain Annotation
comment: Holo-[acyl-carrier-protein] synthase
mass: 13895
range: 18635920295868206tt1tt129

18635920295868206tt1
type: Position
type: ExactPosition
position: 1
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18635920295868206tt129
type: Position
type: ExactPosition
position: 129
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18635920295868206tt8
type: Position
type: ExactPosition
position: 8
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

18635920295868206tt58
type: Position
type: ExactPosition
position: 58
reference: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG

MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 13895

http://purl.uniprot.org/uniprot/B5EQL7#attribution-1F5F5386E209DFCC3422387253639116
manual: true
evidence: ECO_0000255
source: MF_00101

B7JC10
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 77
mnemonic: ACP_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPF018D8BE7E205B4F
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPB2F4547CBC0AD350
annotation: SIP697A1B55F4391B4A
annotation: SIPA99479E04864C047
annotation: SIP02A4F3EAC6E528ED
annotation: SIPB0CD506B89315172
annotation: PRO_1000138992
annotation: SIP9A3FE97698069C6A
annotation: SIP3A7F6F0CA11DDE81
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/596
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0000036
classified with: GO_0031177
sequence: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA
proteome: Chromosome

B7JC10-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0236
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.1200.10
type: Resource
database: Gene3D
comment: ACP-like
signature sequence match: Gene3D 1.10.1200.10 match 1

MF_01217
type: Resource
database: HAMAP
comment: Acyl_carrier
signature sequence match: HAMAP MF 01217 match 1

IPR036736
type: Resource
database: InterPro
comment: ACP-like_sf

IPR003231
type: Resource
database: InterPro
comment: Acyl_carrier

IPR020806
type: Resource
database: InterPro
comment: PKS_PP-bd

IPR009081
type: Resource
database: InterPro
comment: PP-bd_ACP

IPR006162
type: Resource
database: InterPro
comment: Ppantetheine_attach_site

PTHR20863
type: Resource
database: PANTHER
comment: ACYL CARRIER PROTEIN
signature sequence match: PANTHER PTHR20863 match 1

PTHR20863:SF28
type: Resource
database: PANTHER
comment: ACYL CARRIER PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR20863:SF28 match 1

PF00550
type: Resource
database: Pfam
comment: PP-binding
signature sequence match: Pfam PF00550 match 1

SM00823
type: Resource
database: SMART
comment: PKS_PP
signature sequence match: SMART SM00823 match 1

SSF47336
type: Resource
database: SUPFAM
comment: ACP-like
signature sequence match: SUPFAM SSF47336 match 1

TIGR00517
type: Resource
database: TIGRFAMs
comment: acyl_carrier
signature sequence match: TIGRFAMs TIGR00517 match 1

PS50075
type: Resource
database: PROSITE
comment: CARRIER
signature sequence match: PROSITE PS50075 match 1

PS00012
type: Resource
database: PROSITE
comment: PHOSPHOPANTETHEINE
signature sequence match: PROSITE PS00012 match 1

SIPF018D8BE7E205B4F
type: Structured Name
full name: Acyl carrier protein
short name: ACP

acpP
type: Gene
locus name: AFE_1909

SIPB2F4547CBC0AD350
type: Function Annotation
comment: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

SIP02A4F3EAC6E528ED
type: PTM Annotation
comment: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.

SIPB0CD506B89315172
type: Similarity Annotation
comment: Belongs to the acyl carrier protein (ACP) family.

PRO_1000138992
type: Chain Annotation
comment: Acyl carrier protein
mass: 8981
range: 18638140557307950tt1tt82

18638140557307950tt1
type: Position
type: ExactPosition
position: 1
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

18638140557307950tt82
type: Position
type: ExactPosition
position: 82
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

SIP9A3FE97698069C6A
type: Domain Extent Annotation
comment: Carrier
range: 18638140557307950tt2tt77

18638140557307950tt2
type: Position
type: ExactPosition
position: 2
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

18638140557307950tt77
type: Position
type: ExactPosition
position: 77
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

SIP3A7F6F0CA11DDE81
type: Modified Residue Annotation
comment: O-(pantetheine 4'-phosphoryl)serine
range: 18638140557307950tt37tt37

18638140557307950tt37
type: Position
type: ExactPosition
position: 37
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 8981

http://purl.uniprot.org/uniprot/B7JC10#attribution-EBFCF1D44A6B78477DFBD33475E43FB0
manual: true
evidence: ECO_0000255
source: MF_01217

http://purl.uniprot.org/uniprot/B7JC10#attribution-D13C97E04C041CF3567C01508AE538D1
manual: true
evidence: ECO_0000255
source: PRU00258

B5EJD2
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 80
mnemonic: ACP_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPF018D8BE7E205B4F
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP6C3EC65AB5300D97
annotation: SIPAC7E528C6F1DC784
annotation: SIP485CD2A8EA6C641C
annotation: SIP5BEEEE672A99BCD7
annotation: SIP02E72F5E7403CD75
annotation: PRO_1000138993
annotation: SIP32ABB45CFC1B50DF
annotation: SIP43450D95748D74DF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/596
classified with: http://purl.uniprot.org/keywords/597
classified with: GO_0005737
classified with: GO_0000036
classified with: GO_0031177
sequence: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

B5EJD2-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPF018D8BE7E205B4F
type: Structured Name
full name: Acyl carrier protein
short name: ACP

acpP
type: Gene
locus name: Lferr_1584

SIP6C3EC65AB5300D97
type: Function Annotation
comment: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

SIP5BEEEE672A99BCD7
type: PTM Annotation
comment: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.

SIP02E72F5E7403CD75
type: Similarity Annotation
comment: Belongs to the acyl carrier protein (ACP) family.

PRO_1000138993
type: Chain Annotation
comment: Acyl carrier protein
mass: 8981
range: 18635920177902126tt1tt82

18635920177902126tt1
type: Position
type: ExactPosition
position: 1
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

18635920177902126tt82
type: Position
type: ExactPosition
position: 82
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

SIP32ABB45CFC1B50DF
type: Domain Extent Annotation
comment: Carrier
range: 18635920177902126tt2tt77

18635920177902126tt2
type: Position
type: ExactPosition
position: 2
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

18635920177902126tt77
type: Position
type: ExactPosition
position: 77
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

SIP43450D95748D74DF
type: Modified Residue Annotation
comment: O-(pantetheine 4'-phosphoryl)serine
range: 18635920177902126tt37tt37

18635920177902126tt37
type: Position
type: ExactPosition
position: 37
reference: MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA

MDNVADRVKKVVVEQLGVNEDEVTNEASFVDDLGADSLDTVELVMALEEEFDCEIPDEEAEKIATVQQAIDYVSAHIPAKDA
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 8981

http://purl.uniprot.org/uniprot/B5EJD2#attribution-EBFCF1D44A6B78477DFBD33475E43FB0
manual: true
evidence: ECO_0000255
source: MF_01217

http://purl.uniprot.org/uniprot/B5EJD2#attribution-D13C97E04C041CF3567C01508AE538D1
manual: true
evidence: ECO_0000255
source: PRU00258

B7J911
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 74
mnemonic: ALR_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPA9A4E98D933D1F32
enzyme: http://purl.uniprot.org/enzyme/5.1.1.1
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP92B8E2EF47865D4E
annotation: SIPFF483A883E15FBD7
annotation: SIP27E9CD17460147CC
annotation: SIP146B6F20DE505319
annotation: SIPD8368363C5493D97
annotation: PRO_1000164588
annotation: SIPA921963013DC5EA8
annotation: SIPAAA1FF911C048E20
annotation: SIPC4BF2AA306AC89A1
annotation: SIPAB96A63EEA46D9A9
annotation: SIPCE94DD67E60D0093
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0008784
classified with: GO_0030170
classified with: GO_0030632
sequence: B7J911-1
proteome: Chromosome

B7J911-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0787
type: Resource
database: eggNOG
comment: Bacteria

cd06827
type: Resource
database: CDD
comment: PLPDE_III_AR_proteobact
signature sequence match: CDD cd06827 match 1

http://purl.uniprot.org/gene3d/3.20.20.10
type: Resource
database: Gene3D
comment: Alanine racemase
signature sequence match: Gene3D 3.20.20.10 match 1

MF_01201
type: Resource
database: HAMAP
comment: Ala_racemase
signature sequence match: HAMAP MF 01201 match 1

IPR000821
type: Resource
database: InterPro
comment: Ala_racemase

IPR009006
type: Resource
database: InterPro
comment: Ala_racemase/Decarboxylase_C

IPR011079
type: Resource
database: InterPro
comment: Ala_racemase_C

IPR001608
type: Resource
database: InterPro
comment: Ala_racemase_N

IPR020622
type: Resource
database: InterPro
comment: Ala_racemase_pyridoxalP-BS

IPR029066
type: Resource
database: InterPro
comment: PLP-binding_barrel

PTHR30511
type: Resource
database: PANTHER
comment: ALANINE RACEMASE
signature sequence match: PANTHER PTHR30511 match 1

PTHR30511:SF0
type: Resource
database: PANTHER
comment: ALANINE RACEMASE, CATABOLIC-RELATED
signature sequence match: PANTHER PTHR30511:SF0 match 1

PF00842
type: Resource
database: Pfam
comment: Ala_racemase_C
signature sequence match: Pfam PF00842 match 1

PF01168
type: Resource
database: Pfam
comment: Ala_racemase_N
signature sequence match: Pfam PF01168 match 1

PR00992
type: Resource
database: PRINTS
comment: ALARACEMASE

SM01005
type: Resource
database: SMART
comment: Ala_racemase_C
signature sequence match: SMART SM01005 match 1

SSF50621
type: Resource
database: SUPFAM
comment: Alanine racemase C-terminal domain-like
signature sequence match: SUPFAM SSF50621 match 1

SSF51419
type: Resource
database: SUPFAM
comment: PLP-binding barrel
signature sequence match: SUPFAM SSF51419 match 1

TIGR00492
type: Resource
database: TIGRFAMs
comment: alr
signature sequence match: TIGRFAMs TIGR00492 match 1

PS00395
type: Resource
database: PROSITE
comment: ALANINE_RACEMASE
signature sequence match: PROSITE PS00395 match 1

SIPA9A4E98D933D1F32
type: Structured Name
full name: Alanine racemase
ec name: 5.1.1.1

alr
type: Gene
locus name: AFE_2818

SIP92B8E2EF47865D4E
type: Function Annotation
comment: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

SIPD8368363C5493D97
type: Similarity Annotation
comment: Belongs to the alanine racemase family.

PRO_1000164588
type: Chain Annotation
comment: Alanine racemase
mass: 38859
range: 18638140389536046tt1tt364

18638140389536046tt1
type: Position
type: ExactPosition
position: 1
reference: B7J911-1

18638140389536046tt364
type: Position
type: ExactPosition
position: 364
reference: B7J911-1

SIPA921963013DC5EA8
type: Active Site Annotation
comment: Proton acceptor; specific for D-alanine
range: 18638140389536046tt35tt35

18638140389536046tt35
type: Position
type: ExactPosition
position: 35
reference: B7J911-1

SIPAAA1FF911C048E20
type: Active Site Annotation
comment: Proton acceptor; specific for L-alanine
range: 18638140389536046tt260tt260

18638140389536046tt260
type: Position
type: ExactPosition
position: 260
reference: B7J911-1

18638140389536046tt132
type: Position
type: ExactPosition
position: 132
reference: B7J911-1

18638140389536046tt308
type: Position
type: ExactPosition
position: 308
reference: B7J911-1

SIPCE94DD67E60D0093
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18638140389536046tt35tt35

substrate

B7J911-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 38859
value: MTRPIVADISAAALRHNVAVVREHAPRARIMAAVKANAYGHGVTLCAPVLAEAGVDAFAVASLEEAEALHALGLERPICLLGGPFDADEVSVAAERAYLLVIHEQRQLQWLETRAADAALRLFIKVDTGMHRLGFAPERLPALFAALQRHPRWEVLGLMSHLARSDTPDDPFNRQQAGVFADAIAHVGHVTAGQHSLANSGGVLALPFTHQYWVRPGLMLYGLSPFAGRRGSEIGLQPVLSWRSAVVAIRELGPGDWLGYGAAWQAPARCRVGVVAAGYGDGYPRHLGCGAPVTVAGQTTRTLARVSMDMLFVDLTAVEADIGAPVVLMGAGGPPLESLAAELGTISYEMSCRMQMRVPRRLVS

http://purl.uniprot.org/uniprot/B7J911#attribution-35F80A75CD326B6A74A2E2D4A39D726C
manual: true
evidence: ECO_0000255
source: MF_01201

B5EP95
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 81
mnemonic: ALR_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPA9A4E98D933D1F32
enzyme: http://purl.uniprot.org/enzyme/5.1.1.1
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPE4BB686C038AAC1B
annotation: SIPEE1427EB577E809E
annotation: SIP740AA404FB05465F
annotation: SIP5F3D51DFE985453A
annotation: SIPF727B9C9CAACE38D
annotation: PRO_1000164589
annotation: SIP61C07758571FD421
annotation: SIP120BD9FAAD1A15C4
annotation: SIPAE2A0C513F02BBAF
annotation: SIP3E1698CA63BE29C6
annotation: SIPFDA1728F8E78971E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/663
classified with: GO_0008784
classified with: GO_0030170
classified with: GO_0030632
sequence: B5EP95-1

B5EP95-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPA9A4E98D933D1F32
type: Structured Name
full name: Alanine racemase
ec name: 5.1.1.1

alr
type: Gene
locus name: Lferr_2441

SIPE4BB686C038AAC1B
type: Function Annotation
comment: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

SIPF727B9C9CAACE38D
type: Similarity Annotation
comment: Belongs to the alanine racemase family.

PRO_1000164589
type: Chain Annotation
comment: Alanine racemase
mass: 38859
range: 18635920277845294tt1tt364

18635920277845294tt1
type: Position
type: ExactPosition
position: 1
reference: B5EP95-1

18635920277845294tt364
type: Position
type: ExactPosition
position: 364
reference: B5EP95-1

SIP61C07758571FD421
type: Active Site Annotation
comment: Proton acceptor; specific for D-alanine
range: 18635920277845294tt35tt35

18635920277845294tt35
type: Position
type: ExactPosition
position: 35
reference: B5EP95-1

SIP120BD9FAAD1A15C4
type: Active Site Annotation
comment: Proton acceptor; specific for L-alanine
range: 18635920277845294tt260tt260

18635920277845294tt260
type: Position
type: ExactPosition
position: 260
reference: B5EP95-1

18635920277845294tt132
type: Position
type: ExactPosition
position: 132
reference: B5EP95-1

18635920277845294tt308
type: Position
type: ExactPosition
position: 308
reference: B5EP95-1

SIPFDA1728F8E78971E
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18635920277845294tt35tt35

substrate

B5EP95-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 38859
value: MTRPIVADISAAALRHNVAVVREHAPRARIMAAVKANAYGHGVTLCAPVLAEAGVDAFAVASLEEAEALHALGLERPICLLGGPFDADEVSVAAERAYLLVIHEQRQLQWLETRAADAALRLFIKVDTGMHRLGFAPERLPALFAALQRHPRWEVLGLMSHLARSDTPDDPFNRQQAGVFADAIAHVGHVTAGQHSLANSGGVLALPFTHQYWVRPGLMLYGLSPFAGRRGSEIGLQPVLSWRSAVVAIRELGPGDWLGYGAAWQAPARCRVGVVAAGYGDGYPRHLGCGAPVTVAGQTTRTLARVSMDMLFVDLTAVEADIGAPVVLMGAGGPPLESLAAELGTISYEMSCRMQMRVPRRLVS

http://purl.uniprot.org/uniprot/B5EP95#attribution-35F80A75CD326B6A74A2E2D4A39D726C
manual: true
evidence: ECO_0000255
source: MF_01201

B7J5I9
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 67
mnemonic: AMPA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP4C2E197687D5A48E
alternative name: SIP8E066A1821A9A88A
alternative name: SIP2BA06BA51D2DD54D
enzyme: http://purl.uniprot.org/enzyme/3.4.11.1
enzyme: http://purl.uniprot.org/enzyme/3.4.11.10
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP7B876FF938FB0622
annotation: SIP5498562DB2618DBD
annotation: SIP098F64A21F6894C1
annotation: SIP2F30313D3CADDCD0
annotation: SIPD2A29E45E97D063E
annotation: SIP2233B93021C6C5B0
annotation: PRO_1000118444
annotation: SIPF7AAE850290F7CAD
annotation: SIP7BE90D20D68ED2F8
annotation: SIPE847B0D1C901EEEC
annotation: SIP701BF3BCC17925D1
annotation: SIP5C549CD487AD6F6D
annotation: SIPF745554DFC7C4FD7
annotation: SIP9886AE32446EA636
annotation: SIP6F2655B1F274197A
annotation: SIPFC2090465A38EC36
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/31
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0030145
classified with: GO_0070006
classified with: GO_0006508
sequence: B7J5I9-1
proteome: Chromosome

B7J5I9-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0260
type: Resource
database: eggNOG
comment: Bacteria

cd00433
type: Resource
database: CDD
comment: Peptidase_M17
signature sequence match: CDD cd00433 match 1

http://purl.uniprot.org/gene3d/3.40.220.10
type: Resource
database: Gene3D
comment: Leucine Aminopeptidase, subunit E, domain 1
signature sequence match: Gene3D 3.40.220.10 match 1

http://purl.uniprot.org/gene3d/3.40.630.10
type: Resource
database: Gene3D
comment: Zn peptidases
signature sequence match: Gene3D 3.40.630.10 match 1
signature sequence match: Gene3D 3.40.630.10 match 2

MF_00181
type: Resource
database: HAMAP
comment: Cytosol_peptidase_M17
signature sequence match: HAMAP MF 00181 match 1

IPR011356
type: Resource
database: InterPro
comment: Leucine_aapep/pepB

IPR043472
type: Resource
database: InterPro
comment: Macro_dom-like

IPR000819
type: Resource
database: InterPro
comment: Peptidase_M17_C

IPR023042
type: Resource
database: InterPro
comment: Peptidase_M17_leu_NH2_pept

IPR008283
type: Resource
database: InterPro
comment: Peptidase_M17_N

PTHR11963:SF23
type: Resource
database: PANTHER
comment: CYTOSOL AMINOPEPTIDASE
signature sequence match: PANTHER PTHR11963:SF23 match 1

PTHR11963
type: Resource
database: PANTHER
comment: LEUCINE AMINOPEPTIDASE-RELATED
signature sequence match: PANTHER PTHR11963 match 1

PF00883
type: Resource
database: Pfam
comment: Peptidase_M17
signature sequence match: Pfam PF00883 match 1

PF02789
type: Resource
database: Pfam
comment: Peptidase_M17_N
signature sequence match: Pfam PF02789 match 1

PR00481
type: Resource
database: PRINTS
comment: LAMNOPPTDASE

SSF52949
type: Resource
database: SUPFAM
comment: Macro domain-like
signature sequence match: SUPFAM SSF52949 match 1

SSF53187
type: Resource
database: SUPFAM
comment: Zn-dependent exopeptidases
signature sequence match: SUPFAM SSF53187 match 1

PS00631
type: Resource
database: PROSITE
comment: CYTOSOL_AP
signature sequence match: PROSITE PS00631 match 1

SIP4C2E197687D5A48E
type: Structured Name
full name: Probable cytosol aminopeptidase
ec name: 3.4.11.1

SIP8E066A1821A9A88A
type: Structured Name
full name: Leucine aminopeptidase
short name: LAP
ec name: 3.4.11.10

SIP2BA06BA51D2DD54D
type: Structured Name
full name: Leucyl aminopeptidase

pepA
type: Gene
locus name: AFE_2201

SIP7B876FF938FB0622
type: Function Annotation
comment: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

SIP2F30313D3CADDCD0
type: Cofactor Annotation
comment: Binds 2 manganese ions per subunit.
cofactor: CHEBI_29035

SIP2233B93021C6C5B0
type: Similarity Annotation
comment: Belongs to the peptidase M17 family.

PRO_1000118444
type: Chain Annotation
comment: Probable cytosol aminopeptidase
mass: 52844
range: 18638140324002094tt1tt500

18638140324002094tt1
type: Position
type: ExactPosition
position: 1
reference: B7J5I9-1

18638140324002094tt500
type: Position
type: ExactPosition
position: 500
reference: B7J5I9-1

18638140324002094tt281
type: Position
type: ExactPosition
position: 281
reference: B7J5I9-1

18638140324002094tt355
type: Position
type: ExactPosition
position: 355
reference: B7J5I9-1

18638140324002094tt269
type: Position
type: ExactPosition
position: 269
reference: B7J5I9-1

18638140324002094tt274
type: Position
type: ExactPosition
position: 274
reference: B7J5I9-1

18638140324002094tt292
type: Position
type: ExactPosition
position: 292
reference: B7J5I9-1

18638140324002094tt351
type: Position
type: ExactPosition
position: 351
reference: B7J5I9-1

18638140324002094tt353
type: Position
type: ExactPosition
position: 353
reference: B7J5I9-1

2
subclass of: CHEBI_29035

1
subclass of: CHEBI_29035

B7J5I9-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 52844
value: MEIAVQCQNPTTDNSDCVVVGIYEGGILSPAATLVDLASGGALRALLDTGDFTGDCGDTQLLYQVPGMAAARVLVLGLGSHGKVKDSQFRKAALAAARALQGARVGRASLHLLDTPVIRRSAPACAKILVQAVADAEYHFDRHKKPADAPQRPISELQLSISENDTAALAELQGAVAEAQATARAVAWTRDMANEPGNICTPTWLAEQAEAMAGRLGIKSTILGPDAMEALGMHLLLGVAHGSRQPPRLIILEYRGGAENQAPIVLVGKGITFDAGGISLKPADKMDEMKYDMCGGASALAAIQAAAELQLPLNIVTVVPASENLPDGQATKPGDIHRSMNGLSVEVVNTDAEGRLILADTLTYVERFEPDVVIDMATLTGACIIALGHQTAAVMGNHEGLVHDLIAAGKESMDRVWELPLFEEYQEQLKSPVADLSNVGGRPAGTITAACFLSRFTENYRWAHLDIAGVAWKSGEHKGATGRPVPLLVEYLLRRARQVA

http://purl.uniprot.org/uniprot/B7J5I9#attribution-5B745BD8E303FB1FA1AC6F6C6041F55D
manual: true
evidence: ECO_0000255
source: MF_00181

B5EKZ2
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 68
mnemonic: AMPA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP4C2E197687D5A48E
alternative name: SIP8E066A1821A9A88A
alternative name: SIP2BA06BA51D2DD54D
enzyme: http://purl.uniprot.org/enzyme/3.4.11.1
enzyme: http://purl.uniprot.org/enzyme/3.4.11.10
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPF4743DE3A61CE022
annotation: SIP01A5F50FAA65B68C
annotation: SIPE98F534ABECF5937
annotation: SIPF4F3471C1A7E41CC
annotation: SIP6C7BE562B5DE0639
annotation: SIP9DE2652154079D06
annotation: PRO_1000098300
annotation: SIPB7613FAA00FA964C
annotation: SIP4DAAB45456BBC10B
annotation: SIPCC1BEEF21F254A7E
annotation: SIPD5E726BAF3D6A689
annotation: SIP2E0B2A635977EC88
annotation: SIP1E119E0A20447674
annotation: SIPBFDE0CF07FDA0129
annotation: SIP031F954580E05AE3
annotation: SIPC8063EC41A0F7655
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/31
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: GO_0005737
classified with: GO_0030145
classified with: GO_0070006
classified with: GO_0006508
sequence: B5EKZ2-1

B5EKZ2-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP4C2E197687D5A48E
type: Structured Name
full name: Probable cytosol aminopeptidase
ec name: 3.4.11.1

SIP8E066A1821A9A88A
type: Structured Name
full name: Leucine aminopeptidase
short name: LAP
ec name: 3.4.11.10

SIP2BA06BA51D2DD54D
type: Structured Name
full name: Leucyl aminopeptidase

pepA
type: Gene
locus name: Lferr_1857

SIPF4743DE3A61CE022
type: Function Annotation
comment: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

SIPF4F3471C1A7E41CC
type: Cofactor Annotation
comment: Binds 2 manganese ions per subunit.
cofactor: CHEBI_29035

SIP9DE2652154079D06
type: Similarity Annotation
comment: Belongs to the peptidase M17 family.

PRO_1000098300
type: Chain Annotation
comment: Probable cytosol aminopeptidase
mass: 52844
range: 18635920196121134tt1tt500

18635920196121134tt1
type: Position
type: ExactPosition
position: 1
reference: B5EKZ2-1

18635920196121134tt500
type: Position
type: ExactPosition
position: 500
reference: B5EKZ2-1

18635920196121134tt281
type: Position
type: ExactPosition
position: 281
reference: B5EKZ2-1

18635920196121134tt355
type: Position
type: ExactPosition
position: 355
reference: B5EKZ2-1

18635920196121134tt269
type: Position
type: ExactPosition
position: 269
reference: B5EKZ2-1

18635920196121134tt274
type: Position
type: ExactPosition
position: 274
reference: B5EKZ2-1

18635920196121134tt292
type: Position
type: ExactPosition
position: 292
reference: B5EKZ2-1

18635920196121134tt351
type: Position
type: ExactPosition
position: 351
reference: B5EKZ2-1

18635920196121134tt353
type: Position
type: ExactPosition
position: 353
reference: B5EKZ2-1

2
subclass of: CHEBI_29035

1
subclass of: CHEBI_29035

B5EKZ2-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 52844
value: MEIAVQCQNPTTDNSDCVVVGIYEGGILSPAATLVDLASGGALRALLDTGDFTGDCGDTQLLYQVPGMAAARVLVLGLGSHGKVKDSQFRKAALAAARALQGARVGRASLHLLDTPVIRRSAPACAKILVQAVADAEYHFDRHKKPADAPQRPISELQLSISENDTAALAELQGAVAEAQATARAVAWTRDMANEPGNICTPTWLAEQAEAMAGRLGIKSTILGPDAMEALGMHLLLGVAHGSRQPPRLIILEYRGGAENQAPIVLVGKGITFDAGGISLKPADKMDEMKYDMCGGASALAAIQAAAELQLPLNIVTVVPASENLPDGQATKPGDIHRSMNGLSVEVVNTDAEGRLILADTLTYVERFEPDVVIDMATLTGACIIALGHQTAAVMGNHEGLVHDLIAAGKESMDRVWELPLFEEYQEQLKSPVADLSNVGGRPAGTITAACFLSRFTENYRWAHLDIAGVAWKSGEHKGATGRPVPLLVEYLLRRARQVA

http://purl.uniprot.org/uniprot/B5EKZ2#attribution-5B745BD8E303FB1FA1AC6F6C6041F55D
manual: true
evidence: ECO_0000255
source: MF_00181

B7J3S7
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 72
mnemonic: ANMK_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP8D3BD855B979A262
alternative name: SIP0719F4A3ABD6246F
enzyme: http://purl.uniprot.org/enzyme/2.7.1.170
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP2F0C6EE5B6809C8F
annotation: SIP5130F7C8E210DBBB
annotation: SIPF31499FDA01E286A
annotation: SIPF598F9A815C478AB
annotation: SIP7C4C6051DFB172E2
annotation: PRO_1000165149
annotation: SIP9A417C4A7A46A63F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/119
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0016301
classified with: GO_0016773
classified with: GO_0097175
classified with: GO_0006040
classified with: GO_0005975
classified with: GO_0009254
classified with: GO_0016310
sequence: B7J3S7-1
proteome: Chromosome

B7J3S7-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG2377
type: Resource
database: eggNOG
comment: Bacteria

MF_01270
type: Resource
database: HAMAP
comment: AnhMurNAc_kinase
signature sequence match: HAMAP MF 01270 match 1

IPR005338
type: Resource
database: InterPro
comment: Anhydro_N_Ac-Mur_kinase

IPR043129
type: Resource
database: InterPro
comment: ATPase_NBD

PTHR30605
type: Resource
database: PANTHER
comment: ANHYDRO-N-ACETYLMURAMIC ACID KINASE
signature sequence match: PANTHER PTHR30605 match 1

PTHR30605:SF0
type: Resource
database: PANTHER
comment: ANHYDRO-N-ACETYLMURAMIC ACID KINASE
signature sequence match: PANTHER PTHR30605:SF0 match 1

PF03702
type: Resource
database: Pfam
comment: AnmK
signature sequence match: Pfam PF03702 match 1

SSF53067
type: Resource
database: SUPFAM
comment: Actin-like ATPase domain
signature sequence match: SUPFAM SSF53067 match 1
signature sequence match: SUPFAM SSF53067 match 2

SIP8D3BD855B979A262
type: Structured Name
full name: Anhydro-N-acetylmuramic acid kinase
ec name: 2.7.1.170

SIP0719F4A3ABD6246F
type: Structured Name
full name: AnhMurNAc kinase

anmK
type: Gene
locus name: AFE_0181

SIP2F0C6EE5B6809C8F
type: Function Annotation
comment: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

SIP7C4C6051DFB172E2
type: Similarity Annotation
comment: Belongs to the anhydro-N-acetylmuramic acid kinase family.

PRO_1000165149
type: Chain Annotation
comment: Anhydro-N-acetylmuramic acid kinase
mass: 41745
range: 18638140291102510tt1tt393

18638140291102510tt1
type: Position
type: ExactPosition
position: 1
reference: B7J3S7-1

18638140291102510tt393
type: Position
type: ExactPosition
position: 393
reference: B7J3S7-1

18638140291102510tt9
type: Position
type: ExactPosition
position: 9
reference: B7J3S7-1

18638140291102510tt16
type: Position
type: ExactPosition
position: 16
reference: B7J3S7-1

B7J3S7-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 41745
value: MRGLGLMSGTSADGVDAAVLDLAVAGCGGYRGVFTHAFEPALRTEVLAANGPLGVEAMAQLDRRLGACYARVAREAVDRLGPVDFIALHGQTIRHQPRGEPGFTLQIGAAADIAVATGLTVVHDFRRTDVAAGGEGAPLVPPFHQYCFQDEQPRLVLNLGGMANVTWLPGTGDPRPLLAFDCGPGNVLMDAAVELCSAGQATCDVDGRLAAAGQCDVVRLEEWLDHVFFRQAPPKSTGRETFGMPLVTRWWSSWRGSAADFLATLTALTAESVARAVRAWTPGAAEMLVFGGGAENQALMQALQDAMKETRVLHGGRHSGIPGQALEALAFAWLGSQCLLGKRLDLERVTGAQHPMILGNILPGDNWPDLLVQLSQQPEITAREGPYRALRSV

http://purl.uniprot.org/uniprot/B7J3S7#attribution-F3DB2BDD21B051D36DB5D0AA23C5B570
manual: true
evidence: ECO_0000255
source: MF_01270

B7J8G8
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 59
mnemonic: APAG_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPAD7EBDCBBA123ACE
organism: http://purl.uniprot.org/taxonomy/243159
annotation: PRO_1000133778
annotation: SIP3076C8DD06ACC074
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
sequence: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH
proteome: Chromosome

B7J8G8-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG2967
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/2.60.40.1470
type: Resource
database: Gene3D
comment: ApaG domain
signature sequence match: Gene3D 2.60.40.1470 match 1

MF_00791
type: Resource
database: HAMAP
comment: ApaG
signature sequence match: HAMAP MF 00791 match 1

IPR007474
type: Resource
database: InterPro
comment: ApaG_domain

IPR036767
type: Resource
database: InterPro
comment: ApaG_sf

IPR023065
type: Resource
database: InterPro
comment: Uncharacterised_ApaG

PTHR14289
type: Resource
database: PANTHER
comment: F-BOX ONLY PROTEIN 3
signature sequence match: PANTHER PTHR14289 match 1

PTHR14289:SF16
type: Resource
database: PANTHER
comment: POLYMERASE DELTA-INTERACTING PROTEIN 2
signature sequence match: PANTHER PTHR14289:SF16 match 1

PF04379
type: Resource
database: Pfam
comment: DUF525
signature sequence match: Pfam PF04379 match 1

SSF110069
type: Resource
database: SUPFAM
comment: ApaG-like
signature sequence match: SUPFAM SSF110069 match 1

PS51087
type: Resource
database: PROSITE
comment: APAG
signature sequence match: PROSITE PS51087 match 1

SIPAD7EBDCBBA123ACE
type: Structured Name
full name: Protein ApaG

apaG
type: Gene
locus name: AFE_2738

PRO_1000133778
type: Chain Annotation
comment: Protein ApaG
mass: 14069
range: 18638140374202414tt1tt127

18638140374202414tt1
type: Position
type: ExactPosition
position: 1
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

18638140374202414tt127
type: Position
type: ExactPosition
position: 127
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

SIP3076C8DD06ACC074
type: Domain Extent Annotation
comment: ApaG
range: 18638140374202414tt3tt127

18638140374202414tt3
type: Position
type: ExactPosition
position: 3
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 14069

http://purl.uniprot.org/uniprot/B7J8G8#attribution-EC2A511A58BDD012365E19A4E0100665
manual: true
evidence: ECO_0000255
source: MF_00791

B5ENR7
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 62
mnemonic: APAG_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPAD7EBDCBBA123ACE
organism: http://purl.uniprot.org/taxonomy/380394
annotation: PRO_1000133779
annotation: SIP10EDE0B360695443
existence: Inferred from Homology Existence
sequence: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

B5ENR7-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPAD7EBDCBBA123ACE
type: Structured Name
full name: Protein ApaG

apaG
type: Gene
locus name: Lferr_2359

PRO_1000133779
type: Chain Annotation
comment: Protein ApaG
mass: 14069
range: 18635920245929774tt1tt127

18635920245929774tt1
type: Position
type: ExactPosition
position: 1
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

18635920245929774tt127
type: Position
type: ExactPosition
position: 127
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

SIP10EDE0B360695443
type: Domain Extent Annotation
comment: ApaG
range: 18635920245929774tt3tt127

18635920245929774tt3
type: Position
type: ExactPosition
position: 3
reference: MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH

MEDQPPTEIQISVETRYLPEQSSPEQEHFAFAYQITMQNNGPQTAQLLSRHWIITDAEGHVQEVKGPGVVGEQPTLQPGQRFRYTSGSVLSTPVGSMHGTFEWVSDTGESFVVPIPAFRLAAATVFH
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 14069

http://purl.uniprot.org/uniprot/B5ENR7#attribution-EC2A511A58BDD012365E19A4E0100665
manual: true
evidence: ECO_0000255
source: MF_00791

B7JAI2
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 73
mnemonic: ARGC_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP21AA9D787FDBB406
alternative name: SIP59D6176D9B5E4DB4
enzyme: http://purl.uniprot.org/enzyme/1.2.1.38
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP60DA29BB94171F7B
annotation: SIP4CF7720C21D94923
annotation: SIP23611F207039EDBB
annotation: SIP026C8F4B0D8046BE
annotation: SIP72A8E3F6DA6DF3A0
annotation: PRO_1000118051
annotation: SIP8435156BE72068D8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003942
classified with: GO_0051287
classified with: GO_0070401
classified with: GO_0046983
classified with: GO_0006526
sequence: B7JAI2-1
proteome: Chromosome

B7JAI2-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0002
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.40.50.720
type: Resource
database: Gene3D
comment: NAD(P)-binding Rossmann-like Domain
signature sequence match: Gene3D 3.40.50.720 match 1

MF_00150
type: Resource
database: HAMAP
comment: ArgC_type1
signature sequence match: HAMAP MF 00150 match 1

IPR023013
type: Resource
database: InterPro
comment: AGPR_AS

IPR000706
type: Resource
database: InterPro
comment: AGPR_type-1

IPR036291
type: Resource
database: InterPro
comment: NAD(P)-bd_dom_sf

IPR000534
type: Resource
database: InterPro
comment: Semialdehyde_DH_NAD-bd

IPR012280
type: Resource
database: InterPro
comment: Semialdhyde_DH_dimer_dom

PTHR32338:SF10
type: Resource
database: PANTHER
comment: N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE, CHLOROPLASTIC-RELATED
signature sequence match: PANTHER PTHR32338:SF10 match 1

PTHR32338
type: Resource
database: PANTHER
comment: N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE, CHLOROPLASTIC-RELATED-RELATED
signature sequence match: PANTHER PTHR32338 match 1

PF01118
type: Resource
database: Pfam
comment: Semialdhyde_dh
signature sequence match: Pfam PF01118 match 1

PF02774
type: Resource
database: Pfam
comment: Semialdhyde_dhC
signature sequence match: Pfam PF02774 match 1

SM00859
type: Resource
database: SMART
comment: Semialdhyde_dh
signature sequence match: SMART SM00859 match 1

SSF55347
type: Resource
database: SUPFAM
comment: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
signature sequence match: SUPFAM SSF55347 match 1

SSF51735
type: Resource
database: SUPFAM
comment: NAD(P)-binding Rossmann-fold domains
signature sequence match: SUPFAM SSF51735 match 1

TIGR01850
type: Resource
database: TIGRFAMs
comment: argC
signature sequence match: TIGRFAMs TIGR01850 match 1

PS01224
type: Resource
database: PROSITE
comment: ARGC
signature sequence match: PROSITE PS01224 match 1

SIP21AA9D787FDBB406
type: Structured Name
full name: N-acetyl-gamma-glutamyl-phosphate reductase
short name: AGPR
ec name: 1.2.1.38

SIP59D6176D9B5E4DB4
type: Structured Name
full name: N-acetyl-glutamate semialdehyde dehydrogenase
short name: NAGSA dehydrogenase

argC
type: Gene
locus name: AFE_3073

SIP60DA29BB94171F7B
type: Function Annotation
comment: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.

SIP72A8E3F6DA6DF3A0
type: Similarity Annotation
comment: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.

PRO_1000118051
type: Chain Annotation
comment: N-acetyl-gamma-glutamyl-phosphate reductase
mass: 36666
range: 18638140525326894tt1tt344

18638140525326894tt1
type: Position
type: ExactPosition
position: 1
reference: B7JAI2-1

18638140525326894tt344
type: Position
type: ExactPosition
position: 344
reference: B7JAI2-1

18638140525326894tt149
type: Position
type: ExactPosition
position: 149
reference: B7JAI2-1

B7JAI2-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 36666
value: MIRAGIVGGTGYTGVELLRLLLPHPEVELVAITSRAEAGQRVDEHFPNLRGHCNLSYTAPDPAILGTLDVVFFATPHGVAMDSAPKLLAEGVRIIDLGADFRLPDAEVFAQWYGMAHRAPEVLGEACYGLPEYYRTKISEARLIANPGCYPTAVILGLAPLLAEGLLQEDTLIADCKSGVSGAGRSAKVGLILPETADSVSAYGVGGHRHRPEIEAVLSDISGTPLELQFTPHLMPMIRGIHATLYGRLAQPMSDAALQDLFATRYASEPFVDVLPFGSHPATRSVRGANMCLIAVHQPRPGQVVVLSVIDNLVKGAAGQAIQNMNRLFSLAEDAGLMQIALLP

http://purl.uniprot.org/uniprot/B7JAI2#attribution-43D39B81B54D13C15DBBCB68A6E81D52
manual: true
evidence: ECO_0000255
source: MF_00150

B5EQH6
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 76
mnemonic: ARGC_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP21AA9D787FDBB406
alternative name: SIP59D6176D9B5E4DB4
enzyme: http://purl.uniprot.org/enzyme/1.2.1.38
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP7924FACA3A1EE856
annotation: SIP8BA731E0706FFFFB
annotation: SIP925D3B13454BC29E
annotation: SIP7A2FD15E076287DD
annotation: SIPCAC10A28B6CC49B0
annotation: PRO_1000096711
annotation: SIP1BDC6C77CED1D22E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/55
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: GO_0005737
classified with: GO_0003942
classified with: GO_0051287
classified with: GO_0070401
classified with: GO_0046983
classified with: GO_0006526
sequence: B5EQH6-1

B5EQH6-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP21AA9D787FDBB406
type: Structured Name
full name: N-acetyl-gamma-glutamyl-phosphate reductase
short name: AGPR
ec name: 1.2.1.38

SIP59D6176D9B5E4DB4
type: Structured Name
full name: N-acetyl-glutamate semialdehyde dehydrogenase
short name: NAGSA dehydrogenase

argC
type: Gene
locus name: Lferr_2679

SIP7924FACA3A1EE856
type: Function Annotation
comment: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.

SIPCAC10A28B6CC49B0
type: Similarity Annotation
comment: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.

PRO_1000096711
type: Chain Annotation
comment: N-acetyl-gamma-glutamyl-phosphate reductase
mass: 36666
range: 18635920295605806tt1tt344

18635920295605806tt1
type: Position
type: ExactPosition
position: 1
reference: B5EQH6-1

18635920295605806tt344
type: Position
type: ExactPosition
position: 344
reference: B5EQH6-1

18635920295605806tt149
type: Position
type: ExactPosition
position: 149
reference: B5EQH6-1

B5EQH6-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 36666
value: MIRAGIVGGTGYTGVELLRLLLPHPEVELVAITSRAEAGQRVDEHFPNLRGHCNLSYTAPDPAILGTLDVVFFATPHGVAMDSAPKLLAEGVRIIDLGADFRLPDAEVFAQWYGMAHRAPEVLGEACYGLPEYYRTKISEARLIANPGCYPTAVILGLAPLLAEGLLQEDTLIADCKSGVSGAGRSAKVGLILPETADSVSAYGVGGHRHRPEIEAVLSDISGTPLELQFTPHLMPMIRGIHATLYGRLAQPMSDAALQDLFATRYASEPFVDVLPFGSHPATRSVRGANMCLIAVHQPRPGQVVVLSVIDNLVKGAAGQAIQNMNRLFSLAEDAGLMQIALLP

http://purl.uniprot.org/uniprot/B5EQH6#attribution-43D39B81B54D13C15DBBCB68A6E81D52
manual: true
evidence: ECO_0000255
source: MF_00150

B7J781
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 81
mnemonic: AROA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP8ADDB3B43DDAF7EF
annotation: SIP9BD62258220604C9
annotation: SIP33BB9DA2854B5F85
annotation: SIPF3677CC84D782DA7
annotation: SIPE819A2BB97F72B1A
annotation: SIP6FAF4F6A30FCE6E2
annotation: PRO_1000118773
annotation: SIP5ABFCAA2581B4959
annotation: SIPFC397822941BDAA8
annotation: SIP6661667806099D15
annotation: SIPC96D5C042CD665A5
annotation: SIPFC4D4004199BA144
annotation: SIP34A08BFE1983E91E
annotation: SIPF1FF68CC9B5C650C
annotation: SIP4EBEA8158C6742BC
annotation: SIP5086AF0BD0533567
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B7J781-1
proteome: Chromosome

B7J781-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0128
type: Resource
database: eggNOG
comment: Bacteria

cd01556
type: Resource
database: CDD
comment: EPSP_synthase
signature sequence match: CDD cd01556 match 1

http://purl.uniprot.org/gene3d/3.65.10.10
type: Resource
database: Gene3D
comment: Enolpyruvate transferase domain
signature sequence match: Gene3D 3.65.10.10 match 1
signature sequence match: Gene3D 3.65.10.10 match 2

MF_00210
type: Resource
database: HAMAP
comment: EPSP_synth
signature sequence match: HAMAP MF 00210 match 1

IPR001986
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_dom

IPR036968
type: Resource
database: InterPro
comment: Enolpyruvate_Tfrase_sf

IPR006264
type: Resource
database: InterPro
comment: EPSP_synthase

IPR023193
type: Resource
database: InterPro
comment: EPSP_synthase_CS

IPR013792
type: Resource
database: InterPro
comment: RNA3'P_cycl/enolpyr_Trfase_a/b

PTHR21090
type: Resource
database: PANTHER
comment: AROM/DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR21090 match 1

PTHR21090:SF5
type: Resource
database: PANTHER
comment: PENTAFUNCTIONAL AROM POLYPEPTIDE
signature sequence match: PANTHER PTHR21090:SF5 match 1

PF00275
type: Resource
database: Pfam
comment: EPSP_synthase
signature sequence match: Pfam PF00275 match 1

PIRSF000505
type: Resource
database: PIRSF
comment: EPSPS
signature sequence match: PIRSF PIRSF000505 match 1

SSF55205
type: Resource
database: SUPFAM
comment: EPT/RTPC-like
signature sequence match: SUPFAM SSF55205 match 1

TIGR01356
type: Resource
database: TIGRFAMs
comment: aroA
signature sequence match: TIGRFAMs TIGR01356 match 1

PS00104
type: Resource
database: PROSITE
comment: EPSP_SYNTHASE_1
signature sequence match: PROSITE PS00104 match 1

PS00885
type: Resource
database: PROSITE
comment: EPSP_SYNTHASE_2
signature sequence match: PROSITE PS00885 match 1

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: AFE_0901

SIP8ADDB3B43DDAF7EF
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIPF3677CC84D782DA7
type: Subunit Annotation
comment: Monomer.

SIP6FAF4F6A30FCE6E2
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_1000118773
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 44810
range: 18638140356440366tt1tt433

18638140356440366tt1
type: Position
type: ExactPosition
position: 1
reference: B7J781-1

18638140356440366tt433
type: Position
type: ExactPosition
position: 433
reference: B7J781-1

SIP5ABFCAA2581B4959
type: Region Annotation
comment: Phosphoenolpyruvate
range: 18638140356440366tt93tt96

18638140356440366tt93
type: Position
type: ExactPosition
position: 93
reference: B7J781-1

18638140356440366tt96
type: Position
type: ExactPosition
position: 96
reference: B7J781-1

SIPFC397822941BDAA8
type: Active Site Annotation
comment: Proton acceptor
range: 18638140356440366tt314tt314

18638140356440366tt314
type: Position
type: ExactPosition
position: 314
reference: B7J781-1

SIP6661667806099D15
type: Active Site Annotation
comment: Proton donor
range: 18638140356440366tt342tt342

18638140356440366tt342
type: Position
type: ExactPosition
position: 342
reference: B7J781-1

18638140356440366tt22
type: Position
type: ExactPosition
position: 22
reference: B7J781-1

18638140356440366tt23
type: Position
type: ExactPosition
position: 23
reference: B7J781-1

18638140356440366tt27
type: Position
type: ExactPosition
position: 27
reference: B7J781-1

18638140356440366tt123
type: Position
type: ExactPosition
position: 123
reference: B7J781-1

18638140356440366tt341
type: Position
type: ExactPosition
position: 341
reference: B7J781-1

18638140356440366tt345
type: Position
type: ExactPosition
position: 345
reference: B7J781-1

18638140356440366tt386
type: Position
type: ExactPosition
position: 386
reference: B7J781-1

B7J781-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 44810
value: MTRYLVRPGSRLAGRFPVPGDKSISHRAVILGALAEGVTEVEGLLEGADVLATIAAFRSMGVQMEGPDKGHLRIHGAGLQGLRAPVVPLDCGNSGTAMRLLAGVLAGQPFPSTLVGDASLQKRPMGRILNPLRAMGAEIAAQDGRAPLHIHGRPLHGIDYALPVASAQVKSAVLLAGLYADGQTCVTEPAPTRDHSERMLQGFGQPVERHGPRACLRGGGRLCGQALQVPGDISSAAFFLLGATIAPGSDLTLEGVGINPTRTGIIEILTRMGARIDLTALREVGGEPVADIRVRYAPLQGIAIPPRLVPLAIDEFPALFIAAACAKGQTVITGAEELRVKESDRIAVMAGGLRALGATVEERVDGAIISGSALLGGRVDSHGDHRIAMAFAMAALVAQGDMEILDCANVATSFPSFPALAQQAGLLLEVASA

http://purl.uniprot.org/uniprot/B7J781#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

B5EQ20
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 81
mnemonic: AROA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP9B7B8EEDD6AC7691
alternative name: SIP7BCBDA8035E4F966
enzyme: http://purl.uniprot.org/enzyme/2.5.1.19
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP35D9E9407C4F74E5
annotation: SIP03209B77D6D3DE17
annotation: SIP08124B00B339FC61
annotation: SIP65264F4826E0C078
annotation: SIP630D749FD026349F
annotation: SIP18A638F99BA85B5C
annotation: PRO_1000118774
annotation: SIP4478CD9A6FF59682
annotation: SIPD46DE6515ED334D7
annotation: SIPEE683DE18A55F09F
annotation: SIPDF523E0F55486901
annotation: SIP1B9DD1584F9DF31B
annotation: SIP8D6912FAB036FFB1
annotation: SIP9DB445E262E68938
annotation: SIP3F8BE86AD6B62A65
annotation: SIPB223EDA706F5C7B8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0005737
classified with: GO_0003866
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5EQ20-1

B5EQ20-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP9B7B8EEDD6AC7691
type: Structured Name
full name: 3-phosphoshikimate 1-carboxyvinyltransferase
ec name: 2.5.1.19

SIP7BCBDA8035E4F966
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate synthase
short name: EPSP synthase
short name: EPSPS

aroA
type: Gene
locus name: Lferr_1023

SIP35D9E9407C4F74E5
type: Function Annotation
comment: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

SIP65264F4826E0C078
type: Subunit Annotation
comment: Monomer.

SIP18A638F99BA85B5C
type: Similarity Annotation
comment: Belongs to the EPSP synthase family.

PRO_1000118774
type: Chain Annotation
comment: 3-phosphoshikimate 1-carboxyvinyltransferase
mass: 44810
range: 18635920294162478tt1tt433

18635920294162478tt1
type: Position
type: ExactPosition
position: 1
reference: B5EQ20-1

18635920294162478tt433
type: Position
type: ExactPosition
position: 433
reference: B5EQ20-1

SIP4478CD9A6FF59682
type: Region Annotation
comment: Phosphoenolpyruvate
range: 18635920294162478tt93tt96

18635920294162478tt93
type: Position
type: ExactPosition
position: 93
reference: B5EQ20-1

18635920294162478tt96
type: Position
type: ExactPosition
position: 96
reference: B5EQ20-1

SIPD46DE6515ED334D7
type: Active Site Annotation
comment: Proton acceptor
range: 18635920294162478tt314tt314

18635920294162478tt314
type: Position
type: ExactPosition
position: 314
reference: B5EQ20-1

SIPEE683DE18A55F09F
type: Active Site Annotation
comment: Proton donor
range: 18635920294162478tt342tt342

18635920294162478tt342
type: Position
type: ExactPosition
position: 342
reference: B5EQ20-1

18635920294162478tt22
type: Position
type: ExactPosition
position: 22
reference: B5EQ20-1

18635920294162478tt23
type: Position
type: ExactPosition
position: 23
reference: B5EQ20-1

18635920294162478tt27
type: Position
type: ExactPosition
position: 27
reference: B5EQ20-1

18635920294162478tt123
type: Position
type: ExactPosition
position: 123
reference: B5EQ20-1

18635920294162478tt341
type: Position
type: ExactPosition
position: 341
reference: B5EQ20-1

18635920294162478tt345
type: Position
type: ExactPosition
position: 345
reference: B5EQ20-1

18635920294162478tt386
type: Position
type: ExactPosition
position: 386
reference: B5EQ20-1

B5EQ20-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 44810
value: MTRYLVRPGSRLAGRFPVPGDKSISHRAVILGALAEGVTEVEGLLEGADVLATIAAFRSMGVQMEGPDKGHLRIHGAGLQGLRAPVVPLDCGNSGTAMRLLAGVLAGQPFPSTLVGDASLQKRPMGRILNPLRAMGAEIAAQDGRAPLHIHGRPLHGIDYALPVASAQVKSAVLLAGLYADGQTCVTEPAPTRDHSERMLQGFGQPVERHGPRACLRGGGRLCGQALQVPGDISSAAFFLLGATIAPGSDLTLEGVGINPTRTGIIEILTRMGARIDLTALREVGGEPVADIRVRYAPLQGIAIPPRLVPLAIDEFPALFIAAACAKGQTVITGAEELRVKESDRIAVMAGGLRALGATVEERVDGAIISGSALLGGRVDSHGDHRIAMAFAMAALVAQGDMEILDCANVATSFPSFPALAQQAGLLLEVASA

http://purl.uniprot.org/uniprot/B5EQ20#attribution-0A561F4F067256E9CA6406750D5E4A5F
manual: true
evidence: ECO_0000255
source: MF_00210

B7J629
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 81
mnemonic: AROB_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPE69F6258FF124877
annotation: SIPF9C8910E50E85CB5
annotation: SIPA922D27C1F4FE1D8
annotation: SIP032E45C206BCEC35
annotation: SIP208B512F70745F52
annotation: SIPB6F75C8FB3BC28C1
annotation: SIPD624A78191867A96
annotation: PRO_1000117470
annotation: SIP95F3F65320FEF58F
annotation: SIPF8A36D99BAFCD5D0
annotation: SIP48AE85DD2766FBF9
annotation: SIP2DA463C60D0C40E8
annotation: SIPA20396CC38D89BD9
annotation: SIP3185EC25B8F9789B
annotation: SIP406252A411EDFCCE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B7J629-1
proteome: Chromosome

B7J629-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0337
type: Resource
database: eggNOG
comment: Bacteria

cd08195
type: Resource
database: CDD
comment: DHQS
signature sequence match: CDD cd08195 match 1

http://purl.uniprot.org/gene3d/1.20.1090.10
type: Resource
database: Gene3D
comment: Dehydroquinate synthase-like - alpha domain
signature sequence match: Gene3D 1.20.1090.10 match 1

MF_00110
type: Resource
database: HAMAP
comment: DHQ_synthase
signature sequence match: HAMAP MF 00110 match 1

IPR016037
type: Resource
database: InterPro
comment: DHQ_synth_AroB

IPR030963
type: Resource
database: InterPro
comment: DHQ_synth_fam

IPR030960
type: Resource
database: InterPro
comment: DHQS/DOIS

PTHR43622
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE
signature sequence match: PANTHER PTHR43622 match 1

PTHR43622:SF7
type: Resource
database: PANTHER
comment: 3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC
signature sequence match: PANTHER PTHR43622:SF7 match 1

PF01761
type: Resource
database: Pfam
comment: DHQ_synthase
signature sequence match: Pfam PF01761 match 1

PIRSF001455
type: Resource
database: PIRSF
comment: DHQ_synth
signature sequence match: PIRSF PIRSF001455 match 1

SSF56796
type: Resource
database: SUPFAM
comment: Dehydroquinate synthase-like
signature sequence match: SUPFAM SSF56796 match 1

TIGR01357
type: Resource
database: TIGRFAMs
comment: aroB
signature sequence match: TIGRFAMs TIGR01357 match 1

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: AFE_0733

SIPE69F6258FF124877
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIPA922D27C1F4FE1D8
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIPD624A78191867A96
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_1000117470
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 38695
range: 18638140339271982tt1tt364

18638140339271982tt1
type: Position
type: ExactPosition
position: 1
reference: B7J629-1

18638140339271982tt364
type: Position
type: ExactPosition
position: 364
reference: B7J629-1

18638140339271982tt105
type: Position
type: ExactPosition
position: 105
reference: B7J629-1

18638140339271982tt109
type: Position
type: ExactPosition
position: 109
reference: B7J629-1

18638140339271982tt129
type: Position
type: ExactPosition
position: 129
reference: B7J629-1

18638140339271982tt130
type: Position
type: ExactPosition
position: 130
reference: B7J629-1

18638140339271982tt142
type: Position
type: ExactPosition
position: 142
reference: B7J629-1

18638140339271982tt151
type: Position
type: ExactPosition
position: 151
reference: B7J629-1

18638140339271982tt184
type: Position
type: ExactPosition
position: 184
reference: B7J629-1

18638140339271982tt247
type: Position
type: ExactPosition
position: 247
reference: B7J629-1

18638140339271982tt264
type: Position
type: ExactPosition
position: 264
reference: B7J629-1

B7J629-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 38695
value: MRSLCVDLGQRSYPIHTGTGILADSALFAPALSKGPVAVVTDSNVAPLYLETLQKTLKALDKPSLSIILPAGEESKSLDNIQEIAGRLLSAGYGRDCTLCALGGGVVGDITGFAAAVYQRGVAYIQVPTTLLAMVDSSVGGKTGVNHPLGKNMIGAFYQPQAVIADTDTLDSLPEREFRSGLAEVIKYGLINDQGFFSWLEDHMDAVLAREPDALTKVIRHSCKDKADIVARDELEGGLRAILNLGHTFGHAIEAATGYGQYLHGEAVAIGMVMAADLSRRLDLIRESEQDRIYALVEATGLPTLAPALPVADYLGFMRVDKKAEGGRVRFILLRGIGSAVITGEVPPAAITQTLQAFMEHGHA

http://purl.uniprot.org/uniprot/B7J629#attribution-F61B7AC94BE0710BC96CCD11C1C2E895
manual: true
evidence: ECO_0000255
source: MF_00110

B5EP40
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 81
mnemonic: AROB_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPFE5B0953054B33F3
enzyme: http://purl.uniprot.org/enzyme/4.2.3.4
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPA2C8C9C2565E7526
annotation: SIPA252DAE0778594A6
annotation: SIPFEFCF0BB32583A19
annotation: SIP9B5DE704B27C47AA
annotation: SIP6A16C0BBFC3ED6DA
annotation: SIP7E2B187CB24C2822
annotation: SIP82A38DC6D5B01A99
annotation: PRO_1000094443
annotation: SIP2F7D9FB7F7864741
annotation: SIP3E723BF8FF561BC3
annotation: SIP533D5F7EAE04D9EF
annotation: SIP10F975D00CC06563
annotation: SIPC2213C6FD0536072
annotation: SIPC02AE6D7A1D8D0DB
annotation: SIPCFB07782ABFAD3C1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0003856
classified with: GO_0046872
classified with: GO_0000166
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5EP40-1

B5EP40-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPFE5B0953054B33F3
type: Structured Name
full name: 3-dehydroquinate synthase
short name: DHQS
ec name: 4.2.3.4

aroB
type: Gene
locus name: Lferr_0881

SIPA2C8C9C2565E7526
type: Function Annotation
comment: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

SIPFEFCF0BB32583A19
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
cofactor: CHEBI_48828
cofactor: CHEBI_29105

SIP82A38DC6D5B01A99
type: Similarity Annotation
comment: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.

PRO_1000094443
type: Chain Annotation
comment: 3-dehydroquinate synthase
mass: 38695
range: 18635920277516334tt1tt364

18635920277516334tt1
type: Position
type: ExactPosition
position: 1
reference: B5EP40-1

18635920277516334tt364
type: Position
type: ExactPosition
position: 364
reference: B5EP40-1

18635920277516334tt105
type: Position
type: ExactPosition
position: 105
reference: B5EP40-1

18635920277516334tt109
type: Position
type: ExactPosition
position: 109
reference: B5EP40-1

18635920277516334tt129
type: Position
type: ExactPosition
position: 129
reference: B5EP40-1

18635920277516334tt130
type: Position
type: ExactPosition
position: 130
reference: B5EP40-1

18635920277516334tt142
type: Position
type: ExactPosition
position: 142
reference: B5EP40-1

18635920277516334tt151
type: Position
type: ExactPosition
position: 151
reference: B5EP40-1

18635920277516334tt184
type: Position
type: ExactPosition
position: 184
reference: B5EP40-1

18635920277516334tt247
type: Position
type: ExactPosition
position: 247
reference: B5EP40-1

18635920277516334tt264
type: Position
type: ExactPosition
position: 264
reference: B5EP40-1

B5EP40-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 38695
value: MRSLCVDLGQRSYPIHTGTGILADSALFAPALSKGPVAVVTDSNVAPLYLETLQKTLKALDKPSLSIILPAGEESKSLDNIQEIAGRLLSAGYGRDCTLCALGGGVVGDITGFAAAVYQRGVAYIQVPTTLLAMVDSSVGGKTGVNHPLGKNMIGAFYQPQAVIADTDTLDSLPEREFRSGLAEVIKYGLINDQGFFSWLEDHMDAVLAREPDALTKVIRHSCKDKADIVARDELEGGLRAILNLGHTFGHAIEAATGYGQYLHGEAVAIGMVMAADLSRRLDLIRESEQDRIYALVEATGLPTLAPALPVADYLGFMRVDKKAEGGRVRFILLRGIGSAVITGEVPPAAITQTLQAFMEHGHA

http://purl.uniprot.org/uniprot/B5EP40#attribution-F61B7AC94BE0710BC96CCD11C1C2E895
manual: true
evidence: ECO_0000255
source: MF_00110

B7JC67
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 67
mnemonic: AROC_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP26EDFBEC82708729
alternative name: SIPE4438FB08936EFF5
enzyme: http://purl.uniprot.org/enzyme/4.2.3.5
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP9BE07798836C25D1
annotation: SIPC29DCF50718847D2
annotation: SIP768E04447564279C
annotation: SIP3396668A5681FB73
annotation: SIP62DBE9A54C5C9A18
annotation: SIP9048CCA6A0F55365
annotation: PRO_1000119484
annotation: SIP72ACA6E07CD8A978
annotation: SIPB18B5664AF4E4BCD
annotation: SIP90DAAE33843DD3D1
annotation: SIPF676728E1BF10702
annotation: SIPE0470D0965D37B1B
annotation: SIP28DBC0A430D78E0A
annotation: SIP5187F3D890B4CCE7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/274
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004107
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B7JC67-1
proteome: Chromosome

B7JC67-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0082
type: Resource
database: eggNOG
comment: Bacteria

cd07304
type: Resource
database: CDD
comment: Chorismate_synthase
signature sequence match: CDD cd07304 match 1

http://purl.uniprot.org/gene3d/3.60.150.10
type: Resource
database: Gene3D
comment: Chorismate synthase AroC
signature sequence match: Gene3D 3.60.150.10 match 1

MF_00300
type: Resource
database: HAMAP
comment: Chorismate_synth
signature sequence match: HAMAP MF 00300 match 1

IPR000453
type: Resource
database: InterPro
comment: Chorismate_synth

IPR035904
type: Resource
database: InterPro
comment: Chorismate_synth_AroC_sf

IPR020541
type: Resource
database: InterPro
comment: Chorismate_synthase_CS

PTHR21085
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085 match 1

PTHR21085:SF0
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085:SF0 match 1

PF01264
type: Resource
database: Pfam
comment: Chorismate_synt
signature sequence match: Pfam PF01264 match 1

PIRSF001456
type: Resource
database: PIRSF
comment: Chorismate_synth
signature sequence match: PIRSF PIRSF001456 match 1

SSF103263
type: Resource
database: SUPFAM
comment: Chorismate synthase, AroC
signature sequence match: SUPFAM SSF103263 match 1

TIGR00033
type: Resource
database: TIGRFAMs
comment: aroC
signature sequence match: TIGRFAMs TIGR00033 match 1

PS00787
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_1
signature sequence match: PROSITE PS00787 match 1

PS00788
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_2
signature sequence match: PROSITE PS00788 match 1

PS00789
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_3
signature sequence match: PROSITE PS00789 match 1

SIP26EDFBEC82708729
type: Structured Name
full name: Chorismate synthase
short name: CS
ec name: 4.2.3.5

SIPE4438FB08936EFF5
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate phospholyase

aroC
type: Gene
locus name: AFE_1972

SIP9BE07798836C25D1
type: Function Annotation
comment: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

SIP768E04447564279C
type: Cofactor Annotation
comment: Reduced FMN (FMNH(2)).
cofactor: CHEBI_57618

SIP62DBE9A54C5C9A18
type: Subunit Annotation
comment: Homotetramer.

SIP9048CCA6A0F55365
type: Similarity Annotation
comment: Belongs to the chorismate synthase family.

PRO_1000119484
type: Chain Annotation
comment: Chorismate synthase
mass: 38913
range: 18638140557637422tt1tt363

18638140557637422tt1
type: Position
type: ExactPosition
position: 1
reference: B7JC67-1

18638140557637422tt363
type: Position
type: ExactPosition
position: 363
reference: B7JC67-1

18638140557637422tt48
type: Position
type: ExactPosition
position: 48
reference: B7JC67-1

18638140557637422tt54
type: Position
type: ExactPosition
position: 54
reference: B7JC67-1

18638140557637422tt125
type: Position
type: ExactPosition
position: 125
reference: B7JC67-1

18638140557637422tt127
type: Position
type: ExactPosition
position: 127
reference: B7JC67-1

18638140557637422tt238
type: Position
type: ExactPosition
position: 238
reference: B7JC67-1

18638140557637422tt239
type: Position
type: ExactPosition
position: 239
reference: B7JC67-1

18638140557637422tt278
type: Position
type: ExactPosition
position: 278
reference: B7JC67-1

18638140557637422tt293
type: Position
type: ExactPosition
position: 293
reference: B7JC67-1

18638140557637422tt297
type: Position
type: ExactPosition
position: 297
reference: B7JC67-1

18638140557637422tt319
type: Position
type: ExactPosition
position: 319
reference: B7JC67-1

B7JC67-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 38913
value: MAGSSIGECFRVSTFGESHGPAIGCIVDGCPPGMTLSAADIQTELDRRRPGRSRHTTQRQEADQVEILSGVFEGLTTGTPIGLLIRNTDQRSQDYSKIKDLFRPGHADYTYLQKYGLRDYRGGGRSSARETAMRVAAGAIARKFLRERLGVNIQAWMAQMGPIHAEDFDAAEISHNDFFCPDAGAAIRMADFLDGLRKEGDSIGARVDARVSGMPVGLGEPVFDRLEADIAKAMMSINAVKAIAVGDGFAVVEQRGSYHGDAMAATGFQSNHAGGVLGGISSGQDLTLSVAIKPTSSIRIPRQSIDVHGRPAEVITTGRHDPCVGIRAVPIVEAMLALVIMDHWMRHRAQNADVQAPLPPIPA

http://purl.uniprot.org/uniprot/B7JC67#attribution-2F3E6EDFAEDDC061C716E49B15F505C7
manual: true
evidence: ECO_0000255
source: MF_00300

B5EJT1
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 66
mnemonic: AROC_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP26EDFBEC82708729
alternative name: SIPE4438FB08936EFF5
enzyme: http://purl.uniprot.org/enzyme/4.2.3.5
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPC3107725D7D39746
annotation: SIP571DB958BFBF5595
annotation: SIPA16BFD17EC0B4425
annotation: SIPCB45EA1C57406F69
annotation: SIP4784A51136D3415E
annotation: SIP5AA4409D3D082918
annotation: PRO_1000115321
annotation: SIP74797D4B0EE17FF1
annotation: SIP2BAF37CBB764683F
annotation: SIP9FB2D84CD14B45CA
annotation: SIP849141C3F469B631
annotation: SIPAD11242499A36386
annotation: SIP88B288A9AC722E8B
annotation: SIPEDAD25317BBF901A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/274
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/521
classified with: GO_0004107
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: B5EJT1-1

B5EJT1-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP26EDFBEC82708729
type: Structured Name
full name: Chorismate synthase
short name: CS
ec name: 4.2.3.5

SIPE4438FB08936EFF5
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate phospholyase

aroC
type: Gene
locus name: Lferr_1640

SIPC3107725D7D39746
type: Function Annotation
comment: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

SIPA16BFD17EC0B4425
type: Cofactor Annotation
comment: Reduced FMN (FMNH(2)).
cofactor: CHEBI_57618

SIP4784A51136D3415E
type: Subunit Annotation
comment: Homotetramer.

SIP5AA4409D3D082918
type: Similarity Annotation
comment: Belongs to the chorismate synthase family.

PRO_1000115321
type: Chain Annotation
comment: Chorismate synthase
mass: 38913
range: 18635920178950446tt1tt363

18635920178950446tt1
type: Position
type: ExactPosition
position: 1
reference: B5EJT1-1

18635920178950446tt363
type: Position
type: ExactPosition
position: 363
reference: B5EJT1-1

18635920178950446tt48
type: Position
type: ExactPosition
position: 48
reference: B5EJT1-1

18635920178950446tt54
type: Position
type: ExactPosition
position: 54
reference: B5EJT1-1

18635920178950446tt125
type: Position
type: ExactPosition
position: 125
reference: B5EJT1-1

18635920178950446tt127
type: Position
type: ExactPosition
position: 127
reference: B5EJT1-1

18635920178950446tt238
type: Position
type: ExactPosition
position: 238
reference: B5EJT1-1

18635920178950446tt239
type: Position
type: ExactPosition
position: 239
reference: B5EJT1-1

18635920178950446tt278
type: Position
type: ExactPosition
position: 278
reference: B5EJT1-1

18635920178950446tt293
type: Position
type: ExactPosition
position: 293
reference: B5EJT1-1

18635920178950446tt297
type: Position
type: ExactPosition
position: 297
reference: B5EJT1-1

18635920178950446tt319
type: Position
type: ExactPosition
position: 319
reference: B5EJT1-1

B5EJT1-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 38913
value: MAGSSIGECFRVSTFGESHGPAIGCIVDGCPPGMTLSAADIQTELDRRRPGRSRHTTQRQEADQVEILSGVFEGLTTGTPIGLLIRNTDQRSQDYSKIKDLFRPGHADYTYLQKYGLRDYRGGGRSSARETAMRVAAGAIARKFLRERLGVNIQAWMAQMGPIHAEDFDAAEISHNDFFCPDAGAAIRMADFLDGLRKEGDSIGARVDARVSGMPVGLGEPVFDRLEADIAKAMMSINAVKAIAVGDGFAVVEQRGSYHGDAMAATGFQSNHAGGVLGGISSGQDLTLSVAIKPTSSIRIPRQSIDVHGRPAEVITTGRHDPCVGIRAVPIVEAMLALVIMDHWMRHRAQNADVQAPLPPIPA

http://purl.uniprot.org/uniprot/B5EJT1#attribution-2F3E6EDFAEDDC061C716E49B15F505C7
manual: true
evidence: ECO_0000255
source: MF_00300

B7J950
type: Protein
reviewed: true
created: 2015-03-04
modified: 2023-05-03
version: 63
mnemonic: ARREH_ACIF2
citation: http://purl.uniprot.org/citations/19077236
citation: http://purl.uniprot.org/citations/21617342
recommended name: SIPF5D720AC44C3D270
alternative name: SIPFAC63E5F32361BDA
enzyme: http://purl.uniprot.org/enzyme/1.-.-.-
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP0984ADB2FDC84AC1
annotation: SIPD9272D782FA25135
annotation: SIPD3044EDB0F3C5907
annotation: SIP7859B0F696C50FC1
annotation: SIP3D8899BC9BC72204
annotation: SIP0908AEDC570ECC95
annotation: SIP676E5FBC53B703B7
annotation: PRO_0000432219
annotation: SIP545DDF9F33191E6B
annotation: SIPA535BF0C8B24F898
annotation: SIPB27B33B336909090
annotation: SIPAC2ADC64056C986C
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0052851
classified with: GO_0000293
classified with: GO_0010181
classified with: GO_0052873
classified with: GO_0051289
sequence: B7J950-1
proteome: Chromosome

B7J950-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

B7J950-citation-21617342
type: Citation Statement
scope: FUNCTION
scope: CATALYTIC ACTIVITY
scope: COFACTOR
scope: BIOPHYSICOCHEMICAL PROPERTIES
scope: SUBSTRATE SPECIFICITY
scope: MUTAGENESIS OF GLU-104
scope: 3D-STRUCTURE MODELING

COG0431
type: Resource
database: eggNOG
comment: Bacteria

IPR014063
type: Resource
database: InterPro
comment: Arsenate-R_ArsH

IPR029039
type: Resource
database: InterPro
comment: Flavoprotein-like_sf

IPR005025
type: Resource
database: InterPro
comment: FMN_Rdtase-like

PTHR43590
type: Resource
database: PANTHER
comment: ARSENIC RESISTANCE PROTEIN ARSH (AFU_ORTHOLOGUE AFUA_5G15030)
signature sequence match: PANTHER PTHR43590 match 1

PTHR43590:SF1
type: Resource
database: PANTHER
comment: ARSENIC RESISTANCE PROTEIN ARSH (AFU_ORTHOLOGUE AFUA_5G15030)
signature sequence match: PANTHER PTHR43590:SF1 match 1

PF03358
type: Resource
database: Pfam
comment: FMN_red
signature sequence match: Pfam PF03358 match 1

SSF52218
type: Resource
database: SUPFAM
comment: Flavoproteins
signature sequence match: SUPFAM SSF52218 match 1

TIGR02690
type: Resource
database: TIGRFAMs
comment: resist_ArsH
signature sequence match: TIGRFAMs TIGR02690 match 1

SIPF5D720AC44C3D270
type: Structured Name
full name: NADPH-dependent FMN reductase ArsH
ec name: 1.-.-.-

SIPFAC63E5F32361BDA
type: Structured Name
full name: Arsenical resistance operon protein ArsH

arsH
type: Gene
locus name: AFE_2857

SIP0984ADB2FDC84AC1
type: Function Annotation
comment: Has NADPH-dependent FMN reductase activity and high NADPH-dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH, iron trichloride, Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH-dependent ferric reductase in vivo.

SIPD3044EDB0F3C5907
type: Kinetics Annotation
measured affinity: 76 uM for NADPH
measured affinity: 30 uM for Fe(3+)
measured activity: 21.6 umol/min/mg enzyme

SIP7859B0F696C50FC1
type: PH Dependence Annotation
comment: Optimum pH is 6.5 for the ferric reductase activity.

SIP3D8899BC9BC72204
type: Temperature Dependence Annotation
comment: Optimum temperature is 35 degrees Celsius for the ferric reductase activity.

SIP0908AEDC570ECC95
type: Subunit Annotation
comment: Homotetramer.

SIP676E5FBC53B703B7
type: Similarity Annotation
comment: Belongs to the ArsH family.

PRO_0000432219
type: Chain Annotation
comment: NADPH-dependent FMN reductase ArsH
mass: 26871
range: 18638140389797934tt1tt237

18638140389797934tt1
type: Position
type: ExactPosition
position: 1
reference: B7J950-1

18638140389797934tt237
type: Position
type: ExactPosition
position: 237
reference: B7J950-1

18638140389797934tt39
type: Position
type: ExactPosition
position: 39
reference: B7J950-1

18638140389797934tt46
type: Position
type: ExactPosition
position: 46
reference: B7J950-1

18638140389797934tt102
type: Position
type: ExactPosition
position: 102
reference: B7J950-1

18638140389797934tt107
type: Position
type: ExactPosition
position: 107
reference: B7J950-1

SIPB27B33B336909090
type: Mutagenesis Annotation
comment: Loss of ferric reductase activity. Does not bind FMN cofactor.
substitution: A
range: 18638140389797934tt104tt104

18638140389797934tt104
type: Position
type: ExactPosition
position: 104
reference: B7J950-1

SIPAC2ADC64056C986C
type: Mutagenesis Annotation
comment: Strongly reduced ferric reductase activity. Binds FMN cofactor.
substitution: D
substitution: Q
range: 18638140389797934tt104tt104

B7J950-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 26871
value: MSGNLPNTDDVLLQVPDVRCLRSAAETDHPPRILLLYGSNRECSYSRLLTLEAERLLRYFGAETRVFHPTGLPLPDDAPVTHPKVVELQELVEWSEGQVWCSPERHGAMTGVFKSQVDWIPLNSGAIRPTQGKTLALMQVCGGSQSFNAVNQMRILGRWLRMLTIPNQSSVPKAFLEFDDGGRMKPSAYYDRVVDVMEELMKFTLLTRGNSDYLVDRYSERKESAEELSRRVNLQNL

http://purl.uniprot.org/uniprot/B7J950#attribution-845419DEC7A1EEACF21483187C0B059C
creator: UniProtKB
manual: true
evidence: ECO_0000314
source: http://purl.uniprot.org/citations/21617342

http://purl.uniprot.org/uniprot/B7J950#attribution-68097C5C9D39FEEE8BE013645ACBBDD4
creator: UniProtKB
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/B7J950#attribution-50F57AEA1AC0E25B6881297417A02A6C
manual: true
evidence: ECO_0000250
source: Q92R45

http://purl.uniprot.org/uniprot/B7J950#attribution-CF26B2A211536F89DB577AB413F37F49
manual: true
evidence: ECO_0000250
source: Q9I4D4

http://purl.uniprot.org/uniprot/B7J950#attribution-30B87F007C783673FC2A1D78347701D7
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/21617342

http://purl.uniprot.org/uniprot/B7J950#attribution-4743BB95EC4D31F6850790DCEB85D873
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/21617342

http://purl.uniprot.org/uniprot/B7J950#attribution-BB6D3423A7BEDC455B2A76CF87AB3737
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/B7J950#attribution-A7EEDDA48677217F28679480A214EDDF
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/21617342

http://purl.uniprot.org/uniprot/B7J950#attribution-114D71D71DF58A3312794545D251A206
manual: true
evidence: ECO_0000312
source: ACK78531.1

http://purl.uniprot.org/uniprot/B7J950#attribution-DD291B541C122759F60DBD5B618EBD71
manual: true
evidence: ECO_0000312
source: UP000001362

B7JB86
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 81
mnemonic: ATPA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPBE7712CDD879D1B2
alternative name: SIP605D291825F99072
alternative name: SIPA3FE03A31043C3FE
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPC45F93264468F4F5
annotation: SIP13A52BD8D78A3B8D
annotation: SIPD1551D9E03B8D03D
annotation: SIP0E856F10B3D573A4
annotation: SIPC91ACB764574A723
annotation: PRO_1000143332
annotation: SIPF830EFCFFE7A8AC3
annotation: SIP79085FF62EED6AFA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: B7JB86-1
proteome: Chromosome

B7JB86-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0056
type: Resource
database: eggNOG
comment: Bacteria

cd18113
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_C
signature sequence match: CDD cd18113 match 1

cd18116
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_N
signature sequence match: CDD cd18116 match 1

cd01132
type: Resource
database: CDD
comment: F1-ATPase_alpha_CD
signature sequence match: CDD cd01132 match 1

http://purl.uniprot.org/gene3d/1.20.150.20
type: Resource
database: Gene3D
comment: ATP synthase alpha/beta chain, C-terminal domain
signature sequence match: Gene3D 1.20.150.20 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1
signature sequence match: Gene3D 3.40.50.300 match 2

MF_01346
type: Resource
database: HAMAP
comment: ATP_synth_alpha_bact
signature sequence match: HAMAP MF 01346 match 1

IPR023366
type: Resource
database: InterPro
comment: ATP_synth_asu-like_sf

IPR000793
type: Resource
database: InterPro
comment: ATP_synth_asu_C

IPR038376
type: Resource
database: InterPro
comment: ATP_synth_asu_C_sf

IPR033732
type: Resource
database: InterPro
comment: ATP_synth_F1_a_nt-bd_dom

IPR005294
type: Resource
database: InterPro
comment: ATP_synth_F1_asu

IPR020003
type: Resource
database: InterPro
comment: ATPase_a/bsu_AS

IPR004100
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N

IPR036121
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N_sf

IPR000194
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_nucl-bd

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

PTHR48082
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082 match 1

PTHR48082:SF2
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082:SF2 match 1

PF00006
type: Resource
database: Pfam
comment: ATP-synt_ab
signature sequence match: Pfam PF00006 match 1

PF00306
type: Resource
database: Pfam
comment: ATP-synt_ab_C
signature sequence match: Pfam PF00306 match 1

PF02874
type: Resource
database: Pfam
comment: ATP-synt_ab_N
signature sequence match: Pfam PF02874 match 1

PIRSF039088
type: Resource
database: PIRSF
comment: F_ATPase_subunit_alpha
signature sequence match: PIRSF PIRSF039088 match 1

SSF47917
type: Resource
database: SUPFAM
comment: C-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF47917 match 1

SSF50615
type: Resource
database: SUPFAM
comment: N-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF50615 match 1

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1
signature sequence match: SUPFAM SSF52540 match 2

TIGR00962
type: Resource
database: TIGRFAMs
comment: atpA
signature sequence match: TIGRFAMs TIGR00962 match 1

PS00152
type: Resource
database: PROSITE
comment: ATPASE_ALPHA_BETA
signature sequence match: PROSITE PS00152 match 1

SIPBE7712CDD879D1B2
type: Structured Name
full name: ATP synthase subunit alpha
ec name: 7.1.2.2

SIP605D291825F99072
type: Structured Name
full name: ATP synthase F1 sector subunit alpha

SIPA3FE03A31043C3FE
type: Structured Name
full name: F-ATPase subunit alpha

atpA
type: Gene
locus name: AFE_3205

SIPC45F93264468F4F5
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

SIPD1551D9E03B8D03D
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPC91ACB764574A723
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_1000143332
type: Chain Annotation
comment: ATP synthase subunit alpha
mass: 55605
range: 18638140540991022tt1tt514

18638140540991022tt1
type: Position
type: ExactPosition
position: 1
reference: B7JB86-1

18638140540991022tt514
type: Position
type: ExactPosition
position: 514
reference: B7JB86-1

18638140540991022tt170
type: Position
type: ExactPosition
position: 170
reference: B7JB86-1

18638140540991022tt177
type: Position
type: ExactPosition
position: 177
reference: B7JB86-1

SIP79085FF62EED6AFA
type: Site Annotation
comment: Required for activity
range: 18638140540991022tt374tt374

18638140540991022tt374
type: Position
type: ExactPosition
position: 374
reference: B7JB86-1

B7JB86-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 55605
value: MQQLNPSEISELIRARIAGFEGRVETRSQGTIISLSDGILRIHGLEDVMYGEMLELPGGRFGLAMNLEQDNVGAVVLGEFSGLQEGDVVKCTGRVMQVPIGKALLGRVVNALGQPVDGKGAIDAEEFDVLEKIAPGVIDRQSVDEPMQTGIKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAILNQKGKDVQCIYVAIGQKASTVAGVVRKLEEYGAMEYTTVIAANASESAAMQYLAPYAGCTMGEYFRDRGMNALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADFVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIYLETDLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLGGGIRLDLAQYRELAAFAQFASDLDEITRKQIERGKRVTELLKQDQFSPMSVAEQGAALFAASSGALDDVEVANVRPFEKALLAYLNSNNKELMAGIEEKKDLTDDLKKQLDAAVKQFKSGSTY

http://purl.uniprot.org/uniprot/B7JB86#attribution-5C1C7D08C5C30A92BBCA3D89004F22BF
manual: true
evidence: ECO_0000255
source: MF_01346

B5ER44
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 84
mnemonic: ATPA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPBE7712CDD879D1B2
alternative name: SIP605D291825F99072
alternative name: SIPA3FE03A31043C3FE
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPCF1F3321E52ED5EE
annotation: SIP0FF2033E05AC4928
annotation: SIP6ED4A0831A950E2B
annotation: SIP25E346C4F715953E
annotation: SIP0ED3AEF1AABDB522
annotation: PRO_1000143333
annotation: SIP1085CCA8A8D569E1
annotation: SIP015002E992181FD1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: B5ER44-1

B5ER44-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPBE7712CDD879D1B2
type: Structured Name
full name: ATP synthase subunit alpha
ec name: 7.1.2.2

SIP605D291825F99072
type: Structured Name
full name: ATP synthase F1 sector subunit alpha

SIPA3FE03A31043C3FE
type: Structured Name
full name: F-ATPase subunit alpha

atpA
type: Gene
locus name: Lferr_2809

SIPCF1F3321E52ED5EE
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

SIP6ED4A0831A950E2B
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP0ED3AEF1AABDB522
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_1000143333
type: Chain Annotation
comment: ATP synthase subunit alpha
mass: 55605
range: 18635920311071790tt1tt514

18635920311071790tt1
type: Position
type: ExactPosition
position: 1
reference: B5ER44-1

18635920311071790tt514
type: Position
type: ExactPosition
position: 514
reference: B5ER44-1

18635920311071790tt170
type: Position
type: ExactPosition
position: 170
reference: B5ER44-1

18635920311071790tt177
type: Position
type: ExactPosition
position: 177
reference: B5ER44-1

SIP015002E992181FD1
type: Site Annotation
comment: Required for activity
range: 18635920311071790tt374tt374

18635920311071790tt374
type: Position
type: ExactPosition
position: 374
reference: B5ER44-1

B5ER44-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 55605
value: MQQLNPSEISELIRARIAGFEGRVETRSQGTIISLSDGILRIHGLEDVMYGEMLELPGGRFGLAMNLEQDNVGAVVLGEFSGLQEGDVVKCTGRVMQVPIGKALLGRVVNALGQPVDGKGAIDAEEFDVLEKIAPGVIDRQSVDEPMQTGIKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAILNQKGKDVQCIYVAIGQKASTVAGVVRKLEEYGAMEYTTVIAANASESAAMQYLAPYAGCTMGEYFRDRGMNALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADFVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIYLETDLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLGGGIRLDLAQYRELAAFAQFASDLDEITRKQIERGKRVTELLKQDQFSPMSVAEQGAALFAASSGALDDVEVANVRPFEKALLAYLNSNNKELMAGIEEKKDLTDDLKKQLDAAVKQFKSGSTY

http://purl.uniprot.org/uniprot/B5ER44#attribution-5C1C7D08C5C30A92BBCA3D89004F22BF
manual: true
evidence: ECO_0000255
source: MF_01346

P41167
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 126
mnemonic: ATPA_ACIFI
old mnemonic: ATPA_ACIFR
old mnemonic: ATPA_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIPBE7712CDD879D1B2
alternative name: SIP605D291825F99072
alternative name: SIPA3FE03A31043C3FE
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP1670219517A29722
annotation: SIP98160333C09C6D26
annotation: SIP8B28833C8CA710AF
annotation: SIP81A2FC24E4C25C41
annotation: SIP8C9FD8FC0C2103F3
annotation: PRO_0000144363
annotation: SIP180144237AB23755
annotation: SIP9533A571E61C923B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: P41167-1

P41167-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

SIPBE7712CDD879D1B2
type: Structured Name
full name: ATP synthase subunit alpha
ec name: 7.1.2.2

SIP605D291825F99072
type: Structured Name
full name: ATP synthase F1 sector subunit alpha

SIPA3FE03A31043C3FE
type: Structured Name
full name: F-ATPase subunit alpha

atpA
type: Gene

SIP1670219517A29722
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

SIP8B28833C8CA710AF
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP8C9FD8FC0C2103F3
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_0000144363
type: Chain Annotation
comment: ATP synthase subunit alpha
mass: 55601
range: 22575384020530990tt1tt514

22575384020530990tt1
type: Position
type: ExactPosition
position: 1
reference: P41167-1

22575384020530990tt514
type: Position
type: ExactPosition
position: 514
reference: P41167-1

22575384020530990tt170
type: Position
type: ExactPosition
position: 170
reference: P41167-1

22575384020530990tt177
type: Position
type: ExactPosition
position: 177
reference: P41167-1

SIP9533A571E61C923B
type: Site Annotation
comment: Required for activity
range: 22575384020530990tt374tt374

22575384020530990tt374
type: Position
type: ExactPosition
position: 374
reference: P41167-1

P41167-1
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 55601
value: MQQLNPSEISELIRARIAGFEGRVETRSQGTIISLSDGILRIHGLEDVMYGEMLELPGGRFGLAMNLEQDNVGAVVLGEFSGLQEGDVVKCTGRVMQVPIGKALLGRVVNALGQPVDGKGAIDAEEFDVLEKIAPGVIDRQSVDEPMQTGIKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAILNQKGKDVQCIYVAIGQKASTVAGVVRKLEEYGAMEYTTVIAANASESAAMQYLAPYAGCTMGEYFRDRGMNALIVYDDLTKQAWAYRHISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADFVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIYLETDLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLGGGIRLDLAQYRELAAFAQFASDLDEITRKQIERGKRVTELLKQDQFSPMSVADEGAALFAASSGALDDVEVANVRPFEKALLAYLNSNNKELMAGIEEKKDLTDDLKKQLDAAVKQFKSGSTY

http://purl.uniprot.org/uniprot/P41167#attribution-5C1C7D08C5C30A92BBCA3D89004F22BF
manual: true
evidence: ECO_0000255
source: MF_01346

P41168
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 116
mnemonic: ATPB_ACIFI
old mnemonic: ATPB_ACIFR
old mnemonic: ATPB_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIPCABF2B7C796C67AF
alternative name: SIP54BDE05048B44533
alternative name: SIPE5DC476874342920
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIPEFC9704539ABA56D
annotation: SIPA431E8DE95D1E993
annotation: SIP60AD0C8E924A3E77
annotation: SIP25BE8810869EBB3B
annotation: SIP3585379A9E332D83
annotation: PRO_0000144485
annotation: SIP183AD6DF3EBF1D06
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: P41168-1

P41168-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

cd18110
type: Resource
database: CDD
comment: ATP-synt_F1_beta_C
signature sequence match: CDD cd18110 match 1

cd18115
type: Resource
database: CDD
comment: ATP-synt_F1_beta_N
signature sequence match: CDD cd18115 match 1

cd01133
type: Resource
database: CDD
comment: F1-ATPase_beta_CD
signature sequence match: CDD cd01133 match 1

MF_01347
type: Resource
database: HAMAP
comment: ATP_synth_beta_bact
signature sequence match: HAMAP MF 01347 match 1

IPR003593
type: Resource
database: InterPro
comment: AAA+_ATPase

IPR005722
type: Resource
database: InterPro
comment: ATP_synth_F1_bsu

IPR024034
type: Resource
database: InterPro
comment: ATPase_F1/V1_b/a_C

PTHR15184
type: Resource
database: PANTHER
comment: ATP SYNTHASE
signature sequence match: PANTHER PTHR15184 match 1

PTHR15184:SF71
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR15184:SF71 match 1

SM00382
type: Resource
database: SMART
comment: AAA
signature sequence match: SMART SM00382 match 1

TIGR01039
type: Resource
database: TIGRFAMs
comment: atpD
signature sequence match: TIGRFAMs TIGR01039 match 1

SIPCABF2B7C796C67AF
type: Structured Name
full name: ATP synthase subunit beta
ec name: 7.1.2.2

SIP54BDE05048B44533
type: Structured Name
full name: ATP synthase F1 sector subunit beta

SIPE5DC476874342920
type: Structured Name
full name: F-ATPase subunit beta

atpD
type: Gene

SIPEFC9704539ABA56D
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

SIP60AD0C8E924A3E77
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP3585379A9E332D83
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_0000144485
type: Chain Annotation
comment: ATP synthase subunit beta
mass: 50610
range: 22575384020531246tt1tt468

22575384020531246tt1
type: Position
type: ExactPosition
position: 1
reference: P41168-1

22575384020531246tt468
type: Position
type: ExactPosition
position: 468
reference: P41168-1

22575384020531246tt155
type: Position
type: ExactPosition
position: 155
reference: P41168-1

22575384020531246tt162
type: Position
type: ExactPosition
position: 162
reference: P41168-1

P41168-1
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 50610
value: MSERCKENAVGHIVQVIGPVIDVAFSRGQVPEIMEAIVVDANNLTIEVQAQLGDGVARGIAMGPSEGLKRGLAVTRTGAPISVPVGHATLGRIMNVLGEPVDGKGPVQTEDRQAIHRPAPAFDELAASTEVLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVLMMELIRNIAIEHTGYSVFAGVGERTREGNDFYHEMTDSGVLDKVALVYGQMNEPPGNRLRAGLTGLTMAEHFRDEGRDILMFIDNIFRYPLAGTEVSALLGRMPSAVGYQPTLAEEMGQLQERITSTKVGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIAELGIYPALDPLDSFSRQLDPQIVGQEHYDVARSCQKTLQRYKELQDIIAILGMDELSEDDKLLVSRARKIQRYLSQPFFVAEVFTGSPGTYVSLKETIRAFKAIVAGEYDHLPEQAFYMVGTIDEALAKAQKLQQG

http://purl.uniprot.org/uniprot/P41168#attribution-43A9882434E9506AAFC23F741E3F28D4
manual: true
evidence: ECO_0000255
source: MF_01347

B7JB87
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 69
mnemonic: ATPD_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPBD1370672D799AB1
alternative name: SIP998F9CFFBC003414
alternative name: SIP3196E599EDF744CD
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP11E3A886EACC317F
annotation: SIP2BB2F4325BB7BC1D
annotation: SIPDC1FA71914F8E23B
annotation: SIP0F290B8AE9BCACF0
annotation: SIPC24E05775E6476EC
annotation: PRO_1000184633
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0046933
sequence: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS
proteome: Chromosome

B7JB87-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0712
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.520.20
type: Resource
database: Gene3D
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: Gene3D 1.10.520.20 match 1

MF_01416
type: Resource
database: HAMAP
comment: ATP_synth_delta_bact
signature sequence match: HAMAP MF 01416 match 1

IPR026015
type: Resource
database: InterPro
comment: ATP_synth_OSCP/delta_N_sf

IPR020781
type: Resource
database: InterPro
comment: ATPase_OSCP/d_CS

IPR000711
type: Resource
database: InterPro
comment: ATPase_OSCP/dsu

PTHR11910
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA CHAIN
signature sequence match: PANTHER PTHR11910 match 1

PTHR11910:SF22
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, CHLOROPLASTIC
signature sequence match: PANTHER PTHR11910:SF22 match 1

PF00213
type: Resource
database: Pfam
comment: OSCP
signature sequence match: Pfam PF00213 match 1

PR00125
type: Resource
database: PRINTS
comment: ATPASEDELTA

SSF47928
type: Resource
database: SUPFAM
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: SUPFAM SSF47928 match 1

TIGR01145
type: Resource
database: TIGRFAMs
comment: ATP_synt_delta
signature sequence match: TIGRFAMs TIGR01145 match 1

PS00389
type: Resource
database: PROSITE
comment: ATPASE_DELTA
signature sequence match: PROSITE PS00389 match 1

SIPBD1370672D799AB1
type: Structured Name
full name: ATP synthase subunit delta

SIP998F9CFFBC003414
type: Structured Name
full name: ATP synthase F(1) sector subunit delta

SIP3196E599EDF744CD
type: Structured Name
full name: F-type ATPase subunit delta
short name: F-ATPase subunit delta

atpH
type: Gene
locus name: AFE_3206

SIP11E3A886EACC317F
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP2BB2F4325BB7BC1D
type: Function Annotation
comment: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

SIPDC1FA71914F8E23B
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPC24E05775E6476EC
type: Similarity Annotation
comment: Belongs to the ATPase delta chain family.

PRO_1000184633
type: Chain Annotation
comment: ATP synthase subunit delta
mass: 19018
range: 18638140540991278tt1tt179

18638140540991278tt1
type: Position
type: ExactPosition
position: 1
reference: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

18638140540991278tt179
type: Position
type: ExactPosition
position: 179
reference: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 19018

http://purl.uniprot.org/uniprot/B7JB87#attribution-B1DD1792DF5CD88DBD7981631B7C9A70
manual: true
evidence: ECO_0000255
source: MF_01416

B5ER45
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 72
mnemonic: ATPD_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPBD1370672D799AB1
alternative name: SIP998F9CFFBC003414
alternative name: SIP3196E599EDF744CD
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP4B8D6ED3C50A580B
annotation: SIP4342E3E1DCFFCE7B
annotation: SIP36B11A5305E118D2
annotation: SIP112F5D905FB937B2
annotation: SIPF5B7A44EABA4DAE0
annotation: PRO_1000184634
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0046933
sequence: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

B5ER45-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPBD1370672D799AB1
type: Structured Name
full name: ATP synthase subunit delta

SIP998F9CFFBC003414
type: Structured Name
full name: ATP synthase F(1) sector subunit delta

SIP3196E599EDF744CD
type: Structured Name
full name: F-type ATPase subunit delta
short name: F-ATPase subunit delta

atpH
type: Gene
locus name: Lferr_2810

SIP4B8D6ED3C50A580B
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP4342E3E1DCFFCE7B
type: Function Annotation
comment: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

SIP36B11A5305E118D2
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPF5B7A44EABA4DAE0
type: Similarity Annotation
comment: Belongs to the ATPase delta chain family.

PRO_1000184634
type: Chain Annotation
comment: ATP synthase subunit delta
mass: 19018
range: 18635920311072046tt1tt179

18635920311072046tt1
type: Position
type: ExactPosition
position: 1
reference: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

18635920311072046tt179
type: Position
type: ExactPosition
position: 179
reference: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 19018

http://purl.uniprot.org/uniprot/B5ER45#attribution-B1DD1792DF5CD88DBD7981631B7C9A70
manual: true
evidence: ECO_0000255
source: MF_01416

P41170
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 92
mnemonic: ATPD_ACIFI
old mnemonic: ATPD_ACIFR
old mnemonic: ATPD_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIPBD1370672D799AB1
alternative name: SIP998F9CFFBC003414
alternative name: SIP3196E599EDF744CD
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP83FE295AD926EF5E
annotation: SIP6233D106D9C8661F
annotation: SIP1CDC8E6E0BCE7189
annotation: SIP6C107214E402CB8B
annotation: SIPCAE408CCBE2976CD
annotation: PRO_0000193496
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0046933
sequence: MADLITVARPYAEALMGWRKRAARNRPGRMHCRRLPAMIADVQAQAFLTDPERRDAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVRFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

P41170-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

SIPBD1370672D799AB1
type: Structured Name
full name: ATP synthase subunit delta

SIP998F9CFFBC003414
type: Structured Name
full name: ATP synthase F(1) sector subunit delta

SIP3196E599EDF744CD
type: Structured Name
full name: F-type ATPase subunit delta
short name: F-ATPase subunit delta

atpH
type: Gene

SIP83FE295AD926EF5E
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP6233D106D9C8661F
type: Function Annotation
comment: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

SIP1CDC8E6E0BCE7189
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPCAE408CCBE2976CD
type: Similarity Annotation
comment: Belongs to the ATPase delta chain family.

PRO_0000193496
type: Chain Annotation
comment: ATP synthase subunit delta
mass: 19574
range: 22575384020594734tt1tt179

22575384020594734tt1
type: Position
type: ExactPosition
position: 1
reference: MADLITVARPYAEALMGWRKRAARNRPGRMHCRRLPAMIADVQAQAFLTDPERRDAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVRFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

22575384020594734tt179
type: Position
type: ExactPosition
position: 179
reference: MADLITVARPYAEALMGWRKRAARNRPGRMHCRRLPAMIADVQAQAFLTDPERRDAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVRFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS

MADLITVARPYAEALMGWRKRAARNRPGRMHCRRLPAMIADVQAQAFLTDPERRDAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVRFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 19574

http://purl.uniprot.org/uniprot/P41170#attribution-B1DD1792DF5CD88DBD7981631B7C9A70
manual: true
evidence: ECO_0000255
source: MF_01416

P41171
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 102
mnemonic: ATPE_ACIFI
old mnemonic: ATPE_ACIFR
old mnemonic: ATPE_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIP45B225C96B5B8720
alternative name: SIP1A3B8E10330D1A15
alternative name: SIPA309F3952E20E34C
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIPA5395AB006339DEC
annotation: SIP0E716FED7A8BF803
annotation: SIPCB7E32C1E6CF7026
annotation: SIP4B947042CEB56F97
annotation: PRO_0000188233
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
sequence: MAMTIDVRVVSAEGSIYAGVADMVVAPGEMGELGILPRHAPLLTGLRPGELRIIHGAETEYLFVNGGILEIQPDMVTVLADSAERATDIDEAKALAAKQAAEARMAGHTDQMEYAAAQAELLEQIARLKTVQRLREQGFVR

P41171-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

cd12152
type: Resource
database: CDD
comment: F1-ATPase_delta
signature sequence match: CDD cd12152 match 1

http://purl.uniprot.org/gene3d/1.20.5.440
type: Resource
database: Gene3D
comment: ATP synthase delta/epsilon subunit, C-terminal domain
signature sequence match: Gene3D 1.20.5.440 match 1

http://purl.uniprot.org/gene3d/2.60.15.10
type: Resource
database: Gene3D
comment: F0F1 ATP synthase delta/epsilon subunit, N-terminal
signature sequence match: Gene3D 2.60.15.10 match 1

MF_00530
type: Resource
database: HAMAP
comment: ATP_synth_epsil_bac
signature sequence match: HAMAP MF 00530 match 1

IPR036794
type: Resource
database: InterPro
comment: ATP_F1_dsu/esu_C_sf

IPR001469
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu

IPR020546
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu_N

IPR020547
type: Resource
database: InterPro
comment: ATP_synth_F1_esu_C

IPR036771
type: Resource
database: InterPro
comment: ATPsynth_dsu/esu_N

PTHR13822
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA/EPSILON CHAIN
signature sequence match: PANTHER PTHR13822 match 1

PTHR13822:SF7
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR13822:SF7 match 1

PF00401
type: Resource
database: Pfam
comment: ATP-synt_DE
signature sequence match: Pfam PF00401 match 1

PF02823
type: Resource
database: Pfam
comment: ATP-synt_DE_N
signature sequence match: Pfam PF02823 match 1

SSF46604
type: Resource
database: SUPFAM
comment: Epsilon subunit of F1F0-ATP synthase C-terminal domain
signature sequence match: SUPFAM SSF46604 match 1

SSF51344
type: Resource
database: SUPFAM
comment: Epsilon subunit of F1F0-ATP synthase N-terminal domain
signature sequence match: SUPFAM SSF51344 match 1

TIGR01216
type: Resource
database: TIGRFAMs
comment: ATP_synt_epsi
signature sequence match: TIGRFAMs TIGR01216 match 1

SIP45B225C96B5B8720
type: Structured Name
full name: ATP synthase epsilon chain

SIP1A3B8E10330D1A15
type: Structured Name
full name: ATP synthase F1 sector epsilon subunit

SIPA309F3952E20E34C
type: Structured Name
full name: F-ATPase epsilon subunit

atpC
type: Gene

SIPA5395AB006339DEC
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane.

SIP0E716FED7A8BF803
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIP4B947042CEB56F97
type: Similarity Annotation
comment: Belongs to the ATPase epsilon chain family.

PRO_0000188233
type: Chain Annotation
comment: ATP synthase epsilon chain
mass: 15169
range: 22575384020594990tt1tt141

22575384020594990tt1
type: Position
type: ExactPosition
position: 1
reference: MAMTIDVRVVSAEGSIYAGVADMVVAPGEMGELGILPRHAPLLTGLRPGELRIIHGAETEYLFVNGGILEIQPDMVTVLADSAERATDIDEAKALAAKQAAEARMAGHTDQMEYAAAQAELLEQIARLKTVQRLREQGFVR

22575384020594990tt141
type: Position
type: ExactPosition
position: 141
reference: MAMTIDVRVVSAEGSIYAGVADMVVAPGEMGELGILPRHAPLLTGLRPGELRIIHGAETEYLFVNGGILEIQPDMVTVLADSAERATDIDEAKALAAKQAAEARMAGHTDQMEYAAAQAELLEQIARLKTVQRLREQGFVR

MAMTIDVRVVSAEGSIYAGVADMVVAPGEMGELGILPRHAPLLTGLRPGELRIIHGAETEYLFVNGGILEIQPDMVTVLADSAERATDIDEAKALAAKQAAEARMAGHTDQMEYAAAQAELLEQIARLKTVQRLREQGFVR
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 15169

http://purl.uniprot.org/uniprot/P41171#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/P41171#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B7JB88
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 70
mnemonic: ATPF_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP9908B01B6DDF809F
alternative name: SIP2DA520AFF070A505
alternative name: SIP21033C35161E7941
alternative name: SIPAF55909EB1107504
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPBF00A0614597BB78
annotation: SIP84B0922F55FEC829
annotation: SIPA54F8AF333938FEB
annotation: SIPC726F7A0398F2F5C
annotation: SIPFD08A1F14ED6F595
annotation: PRO_0000368283
annotation: SIP657703BD787EE129
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL
proteome: Chromosome

B7JB88-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0711
type: Resource
database: eggNOG
comment: Bacteria

cd06503
type: Resource
database: CDD
comment: ATP-synt_Fo_b
signature sequence match: CDD cd06503 match 1

http://purl.uniprot.org/gene3d/1.20.5.620
type: Resource
database: Gene3D
comment: F1F0 ATP synthase subunit B, membrane domain
signature sequence match: Gene3D 1.20.5.620 match 1

MF_01398
type: Resource
database: HAMAP
comment: ATP_synth_b_bprime
signature sequence match: HAMAP MF 01398 match 1

IPR028987
type: Resource
database: InterPro
comment: ATP_synth_B-like_membr_sf

IPR002146
type: Resource
database: InterPro
comment: ATP_synth_b/b'su_bac/chlpt

IPR005864
type: Resource
database: InterPro
comment: ATP_synth_F0_bsu_bac

PTHR33445:SF1
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B
signature sequence match: PANTHER PTHR33445:SF1 match 1

PTHR33445
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B', CHLOROPLASTIC
signature sequence match: PANTHER PTHR33445 match 1

PF00430
type: Resource
database: Pfam
comment: ATP-synt_B
signature sequence match: Pfam PF00430 match 1

SSF81573
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit B, membrane domain
signature sequence match: SUPFAM SSF81573 match 1

TIGR01144
type: Resource
database: TIGRFAMs
comment: ATP_synt_b
signature sequence match: TIGRFAMs TIGR01144 match 1

SIP9908B01B6DDF809F
type: Structured Name
full name: ATP synthase subunit b

SIP2DA520AFF070A505
type: Structured Name
full name: ATP synthase F(0) sector subunit b

SIP21033C35161E7941
type: Structured Name
full name: ATPase subunit I

SIPAF55909EB1107504
type: Structured Name
full name: F-type ATPase subunit b
short name: F-ATPase subunit b

atpF
type: Gene
locus name: AFE_3207

SIPBF00A0614597BB78
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP84B0922F55FEC829
type: Function Annotation
comment: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).

SIPA54F8AF333938FEB
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPFD08A1F14ED6F595
type: Similarity Annotation
comment: Belongs to the ATPase B chain family.

PRO_0000368283
type: Chain Annotation
comment: ATP synthase subunit b
mass: 17899
range: 18638140540991534tt1tt159

18638140540991534tt1
type: Position
type: ExactPosition
position: 1
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

18638140540991534tt159
type: Position
type: ExactPosition
position: 159
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

SIP657703BD787EE129
type: Transmembrane Annotation
comment: Helical
range: 18638140540991534tt4tt24

18638140540991534tt4
type: Position
type: ExactPosition
position: 4
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

18638140540991534tt24
type: Position
type: ExactPosition
position: 24
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 17899

http://purl.uniprot.org/uniprot/B7JB88#attribution-F532F36C147A4DB2E74653A5DA543EB9
manual: true
evidence: ECO_0000255
source: MF_01398

B5ER46
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 70
mnemonic: ATPF_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP9908B01B6DDF809F
alternative name: SIP2DA520AFF070A505
alternative name: SIP21033C35161E7941
alternative name: SIPAF55909EB1107504
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP44BE2DFB3513ACFE
annotation: SIPB12358A13AE2A41D
annotation: SIPEED1AC23E4B0B693
annotation: SIPC4D5432286680AC2
annotation: SIP4321D12E16FE56DA
annotation: PRO_0000368284
annotation: SIP4ADEAFD368BC2F79
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

B5ER46-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP9908B01B6DDF809F
type: Structured Name
full name: ATP synthase subunit b

SIP2DA520AFF070A505
type: Structured Name
full name: ATP synthase F(0) sector subunit b

SIP21033C35161E7941
type: Structured Name
full name: ATPase subunit I

SIPAF55909EB1107504
type: Structured Name
full name: F-type ATPase subunit b
short name: F-ATPase subunit b

atpF
type: Gene
locus name: Lferr_2811

SIP44BE2DFB3513ACFE
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIPB12358A13AE2A41D
type: Function Annotation
comment: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).

SIPEED1AC23E4B0B693
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP4321D12E16FE56DA
type: Similarity Annotation
comment: Belongs to the ATPase B chain family.

PRO_0000368284
type: Chain Annotation
comment: ATP synthase subunit b
mass: 17899
range: 18635920311072302tt1tt159

18635920311072302tt1
type: Position
type: ExactPosition
position: 1
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

18635920311072302tt159
type: Position
type: ExactPosition
position: 159
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

SIP4ADEAFD368BC2F79
type: Transmembrane Annotation
comment: Helical
range: 18635920311072302tt4tt24

18635920311072302tt4
type: Position
type: ExactPosition
position: 4
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

18635920311072302tt24
type: Position
type: ExactPosition
position: 24
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELLREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 17899

http://purl.uniprot.org/uniprot/B5ER46#attribution-F532F36C147A4DB2E74653A5DA543EB9
manual: true
evidence: ECO_0000255
source: MF_01398

P41172
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 102
mnemonic: ATPF_ACIFI
old mnemonic: ATPF_ACIFR
old mnemonic: ATPF_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIP9908B01B6DDF809F
alternative name: SIP2DA520AFF070A505
alternative name: SIP21033C35161E7941
alternative name: SIPAF55909EB1107504
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP8325ECCF669782EA
annotation: SIPF1DA76FA96A4592D
annotation: SIPEE17D7A9C86604D9
annotation: SIP77FF2EFA0FA17FF8
annotation: SIP8FF9C22342AAF8D6
annotation: PRO_0000082394
annotation: SIPEBCFB7D5709C77C8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

P41172-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

SIP9908B01B6DDF809F
type: Structured Name
full name: ATP synthase subunit b

SIP2DA520AFF070A505
type: Structured Name
full name: ATP synthase F(0) sector subunit b

SIP21033C35161E7941
type: Structured Name
full name: ATPase subunit I

SIPAF55909EB1107504
type: Structured Name
full name: F-type ATPase subunit b
short name: F-ATPase subunit b

atpF
type: Gene

SIP8325ECCF669782EA
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIPF1DA76FA96A4592D
type: Function Annotation
comment: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).

SIPEE17D7A9C86604D9
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP8FF9C22342AAF8D6
type: Similarity Annotation
comment: Belongs to the ATPase B chain family.

PRO_0000082394
type: Chain Annotation
comment: ATP synthase subunit b
mass: 17885
range: 22575384020595246tt1tt159

22575384020595246tt1
type: Position
type: ExactPosition
position: 1
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

22575384020595246tt159
type: Position
type: ExactPosition
position: 159
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

SIPEBCFB7D5709C77C8
type: Transmembrane Annotation
comment: Helical
range: 22575384020595246tt4tt24

22575384020595246tt4
type: Position
type: ExactPosition
position: 4
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

22575384020595246tt24
type: Position
type: ExactPosition
position: 24
reference: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL

MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 17885

http://purl.uniprot.org/uniprot/P41172#attribution-F532F36C147A4DB2E74653A5DA543EB9
manual: true
evidence: ECO_0000255
source: MF_01398

B7JB85
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 71
mnemonic: ATPG_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPA74E809999CB5FD8
alternative name: SIP44F0DB08F4BB3CEB
alternative name: SIP4FE115C883A6523F
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP308EFF8CC019C191
annotation: SIPAA014A2A64BEAE35
annotation: SIPE6E7121099371DCA
annotation: SIPE1036CB4A2BD89D1
annotation: PRO_1000134098
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0042777
sequence: B7JB85-1
proteome: Chromosome

B7JB85-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0224
type: Resource
database: eggNOG
comment: Bacteria

cd12151
type: Resource
database: CDD
comment: F1-ATPase_gamma
signature sequence match: CDD cd12151 match 1

http://purl.uniprot.org/gene3d/1.10.287.80
type: Resource
database: Gene3D
comment: ATP synthase, gamma subunit, helix hairpin domain
signature sequence match: Gene3D 1.10.287.80 match 1

MF_00815
type: Resource
database: HAMAP
comment: ATP_synth_gamma_bact
signature sequence match: HAMAP MF 00815 match 1

IPR035968
type: Resource
database: InterPro
comment: ATP_synth_F1_ATPase_gsu

IPR000131
type: Resource
database: InterPro
comment: ATP_synth_F1_gsu

IPR023632
type: Resource
database: InterPro
comment: ATP_synth_F1_gsu_CS

PTHR11693
type: Resource
database: PANTHER
comment: ATP SYNTHASE GAMMA CHAIN
signature sequence match: PANTHER PTHR11693 match 1

PTHR11693:SF41
type: Resource
database: PANTHER
comment: ATP SYNTHASE GAMMA CHAIN
signature sequence match: PANTHER PTHR11693:SF41 match 1

PF00231
type: Resource
database: Pfam
comment: ATP-synt
signature sequence match: Pfam PF00231 match 1

PR00126
type: Resource
database: PRINTS
comment: ATPASEGAMMA

SSF52943
type: Resource
database: SUPFAM
comment: ATP synthase (F1-ATPase), gamma subunit
signature sequence match: SUPFAM SSF52943 match 1

TIGR01146
type: Resource
database: TIGRFAMs
comment: ATPsyn_F1gamma
signature sequence match: TIGRFAMs TIGR01146 match 1

PS00153
type: Resource
database: PROSITE
comment: ATPASE_GAMMA
signature sequence match: PROSITE PS00153 match 1

SIPA74E809999CB5FD8
type: Structured Name
full name: ATP synthase gamma chain

SIP44F0DB08F4BB3CEB
type: Structured Name
full name: ATP synthase F1 sector gamma subunit

SIP4FE115C883A6523F
type: Structured Name
full name: F-ATPase gamma subunit

atpG
type: Gene
locus name: AFE_3204

SIP308EFF8CC019C191
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

SIPAA014A2A64BEAE35
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPE1036CB4A2BD89D1
type: Similarity Annotation
comment: Belongs to the ATPase gamma chain family.

PRO_1000134098
type: Chain Annotation
comment: ATP synthase gamma chain
mass: 31995
range: 18638140540990766tt1tt288

18638140540990766tt1
type: Position
type: ExactPosition
position: 1
reference: B7JB85-1

18638140540990766tt288
type: Position
type: ExactPosition
position: 288
reference: B7JB85-1

B7JB85-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 31995
value: MANAKEIRGQIKSVKNTRKITRAMEMVAASKMRRAQERMRAARPYAEKIREVLGHLAQAHPEYEHPLMQVRPVKKAGFLVVTTDRGLCGGLNVNVLRNVVQKMRELHEEGVESNLAVVGNKGLGFLRRHGAHLVAELNGLGDSPHLGDMIGPIRAMADAYAKGEVDVVYLVSSRFVNTMLQRATVEQLLPVEKPTASAEQRAELWDYIYEPEARPVLDRLMQRYVESVVYQAVIEHLACEQSARMVAMKSASDNAKRMVDDLQLAYNKARQAAITQEIAEISAGAAAV

http://purl.uniprot.org/uniprot/B7JB85#attribution-0FB3B03FF09B8F0EFB536369EB58B6C4
manual: true
evidence: ECO_0000255
source: MF_00815

B5ER43
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 72
mnemonic: ATPG_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPA74E809999CB5FD8
alternative name: SIP44F0DB08F4BB3CEB
alternative name: SIP4FE115C883A6523F
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP66084AB23C96D16B
annotation: SIP930271EF1B83342E
annotation: SIP1B137B5142868C23
annotation: SIPF8414C5D13CEED94
annotation: PRO_1000134099
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0042777
sequence: B5ER43-1

B5ER43-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPA74E809999CB5FD8
type: Structured Name
full name: ATP synthase gamma chain

SIP44F0DB08F4BB3CEB
type: Structured Name
full name: ATP synthase F1 sector gamma subunit

SIP4FE115C883A6523F
type: Structured Name
full name: F-ATPase gamma subunit

atpG
type: Gene
locus name: Lferr_2808

SIP66084AB23C96D16B
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

SIP930271EF1B83342E
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPF8414C5D13CEED94
type: Similarity Annotation
comment: Belongs to the ATPase gamma chain family.

PRO_1000134099
type: Chain Annotation
comment: ATP synthase gamma chain
mass: 31995
range: 18635920311071534tt1tt288

18635920311071534tt1
type: Position
type: ExactPosition
position: 1
reference: B5ER43-1

18635920311071534tt288
type: Position
type: ExactPosition
position: 288
reference: B5ER43-1

B5ER43-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 31995
value: MANAKEIRGQIKSVKNTRKITRAMEMVAASKMRRAQERMRAARPYAEKIREVLGHLAQAHPEYEHPLMQVRPVKKAGFLVVTTDRGLCGGLNVNVLRNVVQKMRELHEEGVESNLAVVGNKGLGFLRRHGAHLVAELNGLGDSPHLGDMIGPIRAMADAYAKGEVDVVYLVSSRFVNTMLQRATVEQLLPVEKPTASAEQRAELWDYIYEPEARPVLDRLMQRYVESVVYQAVIEHLACEQSARMVAMKSASDNAKRMVDDLQLAYNKARQAAITQEIAEISAGAAAV

http://purl.uniprot.org/uniprot/B5ER43#attribution-0FB3B03FF09B8F0EFB536369EB58B6C4
manual: true
evidence: ECO_0000255
source: MF_00815

P41169
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 100
mnemonic: ATPG_ACIFI
old mnemonic: ATPG_ACIFR
old mnemonic: ATPG_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIPA74E809999CB5FD8
alternative name: SIP44F0DB08F4BB3CEB
alternative name: SIP4FE115C883A6523F
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP9657FA666C205025
annotation: SIP72BB51D5A3E23BC9
annotation: SIPE496419BF019EEDF
annotation: SIPEADD311D1D51A19C
annotation: PRO_0000073408
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0042777
sequence: P41169-1

P41169-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

SIPA74E809999CB5FD8
type: Structured Name
full name: ATP synthase gamma chain

SIP44F0DB08F4BB3CEB
type: Structured Name
full name: ATP synthase F1 sector gamma subunit

SIP4FE115C883A6523F
type: Structured Name
full name: F-ATPase gamma subunit

atpG
type: Gene

SIP9657FA666C205025
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

SIP72BB51D5A3E23BC9
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPEADD311D1D51A19C
type: Similarity Annotation
comment: Belongs to the ATPase gamma chain family.

PRO_0000073408
type: Chain Annotation
comment: ATP synthase gamma chain
mass: 33318
range: 22575384020531502tt1tt298

22575384020531502tt1
type: Position
type: ExactPosition
position: 1
reference: P41169-1

22575384020531502tt298
type: Position
type: ExactPosition
position: 298
reference: P41169-1

P41169-1
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 33318
value: MANAKEIRGQIKSVKNTRKITRAMEMVAASKMRRAQERMRAARPCAEKIREVLGHLAQAHPEYEHPLMQVRPVKKAGFLVVTTDRGLCGGLNVNVLRNVVQKMRELHEEGVESNLAVVGNKGLGFLRRHGAHLVADVNGLGDSPHLGDMIGPIRAMADAYAKGEVDVVYLVSSRFVNTMLQRATVEQLLPVEKPTASAEQRAELWDYIYEPEARPVLDRLMQRYVESVVYQAVIEHLACEQSARMVAMKSASDNAKRMVDDLQLAYNKARQAAITQEIAEISAGAARFDDCAQHFWKF

http://purl.uniprot.org/uniprot/P41169#attribution-0FB3B03FF09B8F0EFB536369EB58B6C4
manual: true
evidence: ECO_0000255
source: MF_00815

B7JB89
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 75
mnemonic: ATPL_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP5FF7173628D234E4
alternative name: SIPB0BFD942ED335F81
alternative name: SIP36C9FA1BB6433AC0
alternative name: SIP47A478988503071F
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP5C2C5FF2968572A3
annotation: SIP3AF5A3CF7D4081E0
annotation: SIPFD21502B2CABD49F
annotation: SIP6CD8A9EE76B1E038
annotation: SIPC004DA3D12695723
annotation: PRO_1000184307
annotation: SIP60695C8EA59A8E37
annotation: SIP824F14B22C983AAF
annotation: SIP387437CA306429BB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/446
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0008289
classified with: GO_0046933
sequence: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG
proteome: Chromosome

B7JB89-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

ENOG5032S3K
type: Resource
database: eggNOG
comment: Bacteria

cd18185
type: Resource
database: CDD
comment: ATP-synt_Fo_c_ATPE
signature sequence match: CDD cd18185 match 1

http://purl.uniprot.org/gene3d/1.20.20.10
type: Resource
database: Gene3D
comment: F1F0 ATP synthase subunit C
signature sequence match: Gene3D 1.20.20.10 match 1

MF_01396
type: Resource
database: HAMAP
comment: ATP_synth_c_bact
signature sequence match: HAMAP MF 01396 match 1

IPR005953
type: Resource
database: InterPro
comment: ATP_synth_csu_bac/chlpt

IPR000454
type: Resource
database: InterPro
comment: ATP_synth_F0_csu

IPR020537
type: Resource
database: InterPro
comment: ATP_synth_F0_csu_DDCD_BS

IPR038662
type: Resource
database: InterPro
comment: ATP_synth_F0_csu_sf

IPR002379
type: Resource
database: InterPro
comment: ATPase_proteolipid_c-like_dom

IPR035921
type: Resource
database: InterPro
comment: F/V-ATP_Csub_sf

PF00137
type: Resource
database: Pfam
comment: ATP-synt_C
signature sequence match: Pfam PF00137 match 1

SSF81333
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit C
signature sequence match: SUPFAM SSF81333 match 1

TIGR01260
type: Resource
database: TIGRFAMs
comment: ATP_synt_c
signature sequence match: TIGRFAMs TIGR01260 match 1

PS00605
type: Resource
database: PROSITE
comment: ATPASE_C
signature sequence match: PROSITE PS00605 match 1

SIP5FF7173628D234E4
type: Structured Name
full name: ATP synthase subunit c

SIPB0BFD942ED335F81
type: Structured Name
full name: ATP synthase F(0) sector subunit c

SIP36C9FA1BB6433AC0
type: Structured Name
full name: F-type ATPase subunit c
short name: F-ATPase subunit c

SIP47A478988503071F
type: Structured Name
full name: Lipid-binding protein

atpE
type: Gene
locus name: AFE_3208

SIP5C2C5FF2968572A3
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP3AF5A3CF7D4081E0
type: Function Annotation
comment: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

SIPFD21502B2CABD49F
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPC004DA3D12695723
type: Similarity Annotation
comment: Belongs to the ATPase C chain family.

PRO_1000184307
type: Chain Annotation
comment: ATP synthase subunit c
mass: 8990
range: 18638140540991790tt1tt84

18638140540991790tt1
type: Position
type: ExactPosition
position: 1
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18638140540991790tt84
type: Position
type: ExactPosition
position: 84
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP60695C8EA59A8E37
type: Transmembrane Annotation
comment: Helical
range: 18638140540991790tt13tt33

18638140540991790tt13
type: Position
type: ExactPosition
position: 13
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18638140540991790tt33
type: Position
type: ExactPosition
position: 33
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP824F14B22C983AAF
type: Transmembrane Annotation
comment: Helical
range: 18638140540991790tt56tt76

18638140540991790tt56
type: Position
type: ExactPosition
position: 56
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18638140540991790tt76
type: Position
type: ExactPosition
position: 76
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP387437CA306429BB
type: Site Annotation
comment: Reversibly protonated during proton transport
range: 18638140540991790tt63tt63

18638140540991790tt63
type: Position
type: ExactPosition
position: 63
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 8990

http://purl.uniprot.org/uniprot/B7JB89#attribution-A30093FC3652A8EBF93668C13F9E1E0F
manual: true
evidence: ECO_0000255
source: MF_01396

B5ER47
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 76
mnemonic: ATPL_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP5FF7173628D234E4
alternative name: SIPB0BFD942ED335F81
alternative name: SIP36C9FA1BB6433AC0
alternative name: SIP47A478988503071F
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP8DFB2165D8BE6E7C
annotation: SIP6C532B8185E5A8F9
annotation: SIPBCFC6C92A06E0089
annotation: SIP9383513ECD5A383F
annotation: SIP8FE1D11F048AF452
annotation: PRO_1000184308
annotation: SIP420D646AF86041B3
annotation: SIP081E3216D438EF37
annotation: SIP6E0BD1D6D72DDD86
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/446
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0008289
classified with: GO_0046933
sequence: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

B5ER47-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP5FF7173628D234E4
type: Structured Name
full name: ATP synthase subunit c

SIPB0BFD942ED335F81
type: Structured Name
full name: ATP synthase F(0) sector subunit c

SIP36C9FA1BB6433AC0
type: Structured Name
full name: F-type ATPase subunit c
short name: F-ATPase subunit c

SIP47A478988503071F
type: Structured Name
full name: Lipid-binding protein

atpE
type: Gene
locus name: Lferr_2812

SIP8DFB2165D8BE6E7C
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP6C532B8185E5A8F9
type: Function Annotation
comment: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

SIPBCFC6C92A06E0089
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP8FE1D11F048AF452
type: Similarity Annotation
comment: Belongs to the ATPase C chain family.

PRO_1000184308
type: Chain Annotation
comment: ATP synthase subunit c
mass: 8990
range: 18635920311072558tt1tt84

18635920311072558tt1
type: Position
type: ExactPosition
position: 1
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18635920311072558tt84
type: Position
type: ExactPosition
position: 84
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP420D646AF86041B3
type: Transmembrane Annotation
comment: Helical
range: 18635920311072558tt13tt33

18635920311072558tt13
type: Position
type: ExactPosition
position: 13
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18635920311072558tt33
type: Position
type: ExactPosition
position: 33
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP081E3216D438EF37
type: Transmembrane Annotation
comment: Helical
range: 18635920311072558tt56tt76

18635920311072558tt56
type: Position
type: ExactPosition
position: 56
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

18635920311072558tt76
type: Position
type: ExactPosition
position: 76
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIP6E0BD1D6D72DDD86
type: Site Annotation
comment: Reversibly protonated during proton transport
range: 18635920311072558tt63tt63

18635920311072558tt63
type: Position
type: ExactPosition
position: 63
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 8990

http://purl.uniprot.org/uniprot/B5ER47#attribution-A30093FC3652A8EBF93668C13F9E1E0F
manual: true
evidence: ECO_0000255
source: MF_01396

P41173
type: Protein
reviewed: true
created: 1995-02-01
modified: 2023-05-03
version: 112
mnemonic: ATPL_ACIFI
old mnemonic: ATPL_ACIFR
old mnemonic: ATPL_THIFE
citation: http://purl.uniprot.org/citations/7958772
recommended name: SIP5FF7173628D234E4
alternative name: SIPB0BFD942ED335F81
alternative name: SIP36C9FA1BB6433AC0
alternative name: SIP47A478988503071F
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP271161D253962CBC
annotation: SIP7BAFD380F03F01EF
annotation: SIP816A18B5056008A0
annotation: SIPECDDA3D34CF27D74
annotation: SIP240AF7579193CB20
annotation: PRO_0000112174
annotation: SIPD3B94E37F8186CE0
annotation: SIPFECF5BF7B0942C35
annotation: SIPA8D3DE39EC2407D2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/446
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0008289
classified with: GO_0046933
sequence: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

P41173-citation-7958772
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

SIP5FF7173628D234E4
type: Structured Name
full name: ATP synthase subunit c

SIPB0BFD942ED335F81
type: Structured Name
full name: ATP synthase F(0) sector subunit c

SIP36C9FA1BB6433AC0
type: Structured Name
full name: F-type ATPase subunit c
short name: F-ATPase subunit c

SIP47A478988503071F
type: Structured Name
full name: Lipid-binding protein

atpE
type: Gene

SIP271161D253962CBC
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP7BAFD380F03F01EF
type: Function Annotation
comment: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

SIP816A18B5056008A0
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP240AF7579193CB20
type: Similarity Annotation
comment: Belongs to the ATPase C chain family.

PRO_0000112174
type: Chain Annotation
comment: ATP synthase subunit c
mass: 8990
range: 22575384020595502tt1tt84

22575384020595502tt1
type: Position
type: ExactPosition
position: 1
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

22575384020595502tt84
type: Position
type: ExactPosition
position: 84
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIPD3B94E37F8186CE0
type: Transmembrane Annotation
comment: Helical
range: 22575384020595502tt13tt33

22575384020595502tt13
type: Position
type: ExactPosition
position: 13
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

22575384020595502tt33
type: Position
type: ExactPosition
position: 33
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIPFECF5BF7B0942C35
type: Transmembrane Annotation
comment: Helical
range: 22575384020595502tt56tt76

22575384020595502tt56
type: Position
type: ExactPosition
position: 56
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

22575384020595502tt76
type: Position
type: ExactPosition
position: 76
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

SIPA8D3DE39EC2407D2
type: Site Annotation
comment: Reversibly protonated during proton transport
range: 22575384020595502tt63tt63

22575384020595502tt63
type: Position
type: ExactPosition
position: 63
reference: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG

MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG
type: Simple Sequence
modified: 1995-02-01
version: 1
mass: 8990

http://purl.uniprot.org/uniprot/P41173#attribution-A30093FC3652A8EBF93668C13F9E1E0F
manual: true
evidence: ECO_0000255
source: MF_01396

B7J403
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 77
mnemonic: BIOB_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPBB15AFB22594DDF3
enzyme: http://purl.uniprot.org/enzyme/2.8.1.6
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPA46DFD0532F0790D
annotation: SIP41C6A74FD39F6C8F
annotation: SIPAE9AF884D728860A
annotation: SIP3984F87317F25D82
annotation: SIPF2F11FD27CD693E2
annotation: SIPFDA302A4761D100F
annotation: SIP2C58A03D703EC857
annotation: PRO_0000381177
annotation: SIP82143604516C72FA
annotation: SIP0773292E32057ABC
annotation: SIPDA899D1622CDE6DC
annotation: SIP6840C8157907030A
annotation: SIPB6D229E56A13FA4D
annotation: SIPEAE9D1485CD2E740
annotation: SIPB3CF20D63D828B2D
annotation: SIP8CF1C044740E8020
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/949
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0051537
classified with: GO_0051539
classified with: GO_0004076
classified with: GO_0005506
classified with: GO_0009102
sequence: B7J403-1
proteome: Chromosome

B7J403-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0502
type: Resource
database: eggNOG
comment: Bacteria

cd01335
type: Resource
database: CDD
comment: Radical_SAM
signature sequence match: CDD cd01335 match 1

http://purl.uniprot.org/gene3d/3.20.20.70
type: Resource
database: Gene3D
comment: Aldolase class I
signature sequence match: Gene3D 3.20.20.70 match 1

MF_01694
type: Resource
database: HAMAP
comment: BioB
signature sequence match: HAMAP MF 01694 match 1

IPR013785
type: Resource
database: InterPro
comment: Aldolase_TIM

IPR010722
type: Resource
database: InterPro
comment: BATS_dom

IPR002684
type: Resource
database: InterPro
comment: Biotin_synth/BioAB

IPR024177
type: Resource
database: InterPro
comment: Biotin_synthase

IPR006638
type: Resource
database: InterPro
comment: Elp3/MiaA/NifB-like_rSAM

IPR007197
type: Resource
database: InterPro
comment: rSAM

PTHR22976
type: Resource
database: PANTHER
comment: BIOTIN SYNTHASE
signature sequence match: PANTHER PTHR22976 match 1

PTHR22976:SF2
type: Resource
database: PANTHER
comment: BIOTIN SYNTHASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR22976:SF2 match 1

PF06968
type: Resource
database: Pfam
comment: BATS
signature sequence match: Pfam PF06968 match 1

PF04055
type: Resource
database: Pfam
comment: Radical_SAM
signature sequence match: Pfam PF04055 match 1

PIRSF001619
type: Resource
database: PIRSF
comment: Biotin_synth
signature sequence match: PIRSF PIRSF001619 match 1

SFLDF00272
type: Resource
database: SFLD
comment: biotin_synthase
signature sequence match: SFLD SFLDF00272 match 1

SFLDG01278
type: Resource
database: SFLD
comment: biotin_synthase_like
signature sequence match: SFLD SFLDG01278 match 1

SM00876
type: Resource
database: SMART
comment: BATS
signature sequence match: SMART SM00876 match 1

SM00729
type: Resource
database: SMART
comment: Elp3
signature sequence match: SMART SM00729 match 1

SSF102114
type: Resource
database: SUPFAM
comment: Radical SAM enzymes
signature sequence match: SUPFAM SSF102114 match 1

TIGR00433
type: Resource
database: TIGRFAMs
comment: bioB
signature sequence match: TIGRFAMs TIGR00433 match 1

PS51918
type: Resource
database: PROSITE
comment: RADICAL_SAM
signature sequence match: PROSITE PS51918 match 1

SIPBB15AFB22594DDF3
type: Structured Name
full name: Biotin synthase
ec name: 2.8.1.6

bioB
type: Gene
locus name: AFE_0259

SIPA46DFD0532F0790D
type: Function Annotation
comment: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.

SIPAE9AF884D728860A
type: Cofactor Annotation
comment: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
cofactor: CHEBI_49883

SIP3984F87317F25D82
type: Cofactor Annotation
comment: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
cofactor: CHEBI_190135

SIPFDA302A4761D100F
type: Subunit Annotation
comment: Homodimer.

SIP2C58A03D703EC857
type: Similarity Annotation
comment: Belongs to the radical SAM superfamily. Biotin synthase family.

PRO_0000381177
type: Chain Annotation
comment: Biotin synthase
mass: 34539
range: 18638140305584942tt1tt316

18638140305584942tt1
type: Position
type: ExactPosition
position: 1
reference: B7J403-1

18638140305584942tt316
type: Position
type: ExactPosition
position: 316
reference: B7J403-1

SIP82143604516C72FA
type: Domain Extent Annotation
comment: Radical SAM core
range: 18638140305584942tt39tt263

18638140305584942tt39
type: Position
type: ExactPosition
position: 39
reference: B7J403-1

18638140305584942tt263
type: Position
type: ExactPosition
position: 263
reference: B7J403-1

18638140305584942tt54
type: Position
type: ExactPosition
position: 54
reference: B7J403-1

18638140305584942tt58
type: Position
type: ExactPosition
position: 58
reference: B7J403-1

18638140305584942tt61
type: Position
type: ExactPosition
position: 61
reference: B7J403-1

18638140305584942tt98
type: Position
type: ExactPosition
position: 98
reference: B7J403-1

18638140305584942tt129
type: Position
type: ExactPosition
position: 129
reference: B7J403-1

18638140305584942tt189
type: Position
type: ExactPosition
position: 189
reference: B7J403-1

18638140305584942tt261
type: Position
type: ExactPosition
position: 261
reference: B7J403-1

SIP0EB8875058CDA956
subclass of: CHEBI_49883
comment: 4Fe-4S-S-AdoMet

B7J403-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 34539
value: MNNSTALQTLDAILEIYARPFNDLIYAAQQVHRLHFDPNAIQCSTLLSIKTGGCPEDCGYCSQSVHHQTALQAEPLMDLEQVRAAAREAKANGAQRLCMGAAWRSPHDRDIEKVAAMIGVVKEYGLESCVTLGMLKPGQAERLQHAGLDYYNHNLDTSPEFYGEVIHTRSYQDRLDTLEAVRDAGIRICSGGILGMGESRRDRARMLQVLAQLPQAPESIPINALVPIPGTPLEAAEPIDGFEFVRTVAVTRILFPKAYVRLSAGREAMSDELQALAFLAGANSIFLGDRLLTTGNASTGHDQALFNRLGLHRSAD

http://purl.uniprot.org/uniprot/B7J403#attribution-55428B9244A0EC48C2387090F66C8227
manual: true
evidence: ECO_0000255
source: MF_01694

http://purl.uniprot.org/uniprot/B7J403#attribution-3F4EA4141FE4507DF0695D0A72C2893B
manual: true
evidence: ECO_0000255
source: PRU01266

B5ELR8
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 78
mnemonic: BIOB_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPBB15AFB22594DDF3
enzyme: http://purl.uniprot.org/enzyme/2.8.1.6
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP162138D705963192
annotation: SIPBC251A9E1E96F180
annotation: SIP4221EC4D7D2A9E4D
annotation: SIP27857F2A93B42062
annotation: SIP6D7548D539E67B08
annotation: SIPD1603DC05ADD4A60
annotation: SIP281B8A44D1F3C791
annotation: PRO_0000381178
annotation: SIP90EC2FF60D906AD5
annotation: SIPFAF784D7295BF130
annotation: SIP23DA9DD54F91E724
annotation: SIP658421D58084DABC
annotation: SIPF89EBF6693A58D76
annotation: SIP32173E6FB4251DAC
annotation: SIP996DBE0FB0A1891D
annotation: SIPDEFBC80D90D71C85
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/949
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0051537
classified with: GO_0051539
classified with: GO_0004076
classified with: GO_0005506
classified with: GO_0009102
sequence: B5ELR8-1

B5ELR8-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPBB15AFB22594DDF3
type: Structured Name
full name: Biotin synthase
ec name: 2.8.1.6

bioB
type: Gene
locus name: Lferr_0436

SIP162138D705963192
type: Function Annotation
comment: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.

SIP4221EC4D7D2A9E4D
type: Cofactor Annotation
comment: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
cofactor: CHEBI_49883

SIP27857F2A93B42062
type: Cofactor Annotation
comment: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
cofactor: CHEBI_190135

SIPD1603DC05ADD4A60
type: Subunit Annotation
comment: Homodimer.

SIP281B8A44D1F3C791
type: Similarity Annotation
comment: Belongs to the radical SAM superfamily. Biotin synthase family.

PRO_0000381178
type: Chain Annotation
comment: Biotin synthase
mass: 34539
range: 18635920212375598tt1tt316

18635920212375598tt1
type: Position
type: ExactPosition
position: 1
reference: B5ELR8-1

18635920212375598tt316
type: Position
type: ExactPosition
position: 316
reference: B5ELR8-1

SIP90EC2FF60D906AD5
type: Domain Extent Annotation
comment: Radical SAM core
range: 18635920212375598tt39tt263

18635920212375598tt39
type: Position
type: ExactPosition
position: 39
reference: B5ELR8-1

18635920212375598tt263
type: Position
type: ExactPosition
position: 263
reference: B5ELR8-1

18635920212375598tt54
type: Position
type: ExactPosition
position: 54
reference: B5ELR8-1

18635920212375598tt58
type: Position
type: ExactPosition
position: 58
reference: B5ELR8-1

18635920212375598tt61
type: Position
type: ExactPosition
position: 61
reference: B5ELR8-1

18635920212375598tt98
type: Position
type: ExactPosition
position: 98
reference: B5ELR8-1

18635920212375598tt129
type: Position
type: ExactPosition
position: 129
reference: B5ELR8-1

18635920212375598tt189
type: Position
type: ExactPosition
position: 189
reference: B5ELR8-1

18635920212375598tt261
type: Position
type: ExactPosition
position: 261
reference: B5ELR8-1

SIP0EB8875058CDA956
subclass of: CHEBI_49883
comment: 4Fe-4S-S-AdoMet

B5ELR8-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 34539
value: MNNSTALQTLDAILEIYARPFNDLIYAAQQVHRLHFDPNAIQCSTLLSIKTGGCPEDCGYCSQSVHHQTALQAEPLMDLEQVRAAAREAKANGAQRLCMGAAWRSPHDRDIEKVAAMIGVVKEYGLESCVTLGMLKPGQAERLQHAGLDYYNHNLDTSPEFYGEVIHTRSYQDRLDTLEAVRDAGIRICSGGILGMGESRRDRARMLQVLAQLPQAPESIPINALVPIPGTPLEAAEPIDGFEFVRTVAVTRILFPKAYVRLSAGREAMSDELQALAFLAGANSIFLGDRLLTTGNASTGHDQALFNRLGLHRSAD

http://purl.uniprot.org/uniprot/B5ELR8#attribution-55428B9244A0EC48C2387090F66C8227
manual: true
evidence: ECO_0000255
source: MF_01694

http://purl.uniprot.org/uniprot/B5ELR8#attribution-3F4EA4141FE4507DF0695D0A72C2893B
manual: true
evidence: ECO_0000255
source: PRU01266

B7J3Y7
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 76
mnemonic: BIOF_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPD7ADB99A00D2D6E0
alternative name: SIP6AA432A4A9DA7749
alternative name: SIPD3A475FA85257690
enzyme: http://purl.uniprot.org/enzyme/2.3.1.47
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP19C555523742FF25
annotation: SIP64E6B7EEE780E8AD
annotation: SIPAC996DC8EC679941
annotation: SIPB31A5BC278531828
annotation: SIPEC5778632C099B40
annotation: SIP20E518F6518089AB
annotation: PRO_0000380885
annotation: SIP3642058780DBA10C
annotation: SIP00AADEBDCE781F46
annotation: SIP8B783DC0BB79014C
annotation: SIPD93BFBFE94E9B9BF
annotation: SIP8D3716389CE0D131
annotation: SIP58B81248D2960FF4
annotation: SIP05168E433C9B9765
annotation: SIP35410EBC1DE5CAC3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0008710
classified with: GO_0030170
classified with: GO_0009102
sequence: B7J3Y7-1
proteome: Chromosome

B7J3Y7-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0156
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.90.1150.10
type: Resource
database: Gene3D
comment: Aspartate Aminotransferase, domain 1
signature sequence match: Gene3D 3.90.1150.10 match 1

http://purl.uniprot.org/gene3d/3.40.640.10
type: Resource
database: Gene3D
comment: Type I PLP-dependent aspartate aminotransferase-like (Major domain)
signature sequence match: Gene3D 3.40.640.10 match 1

MF_01693
type: Resource
database: HAMAP
comment: BioF_aminotrans_2
signature sequence match: HAMAP MF 01693 match 1

IPR001917
type: Resource
database: InterPro
comment: Aminotrans_II_pyridoxalP_BS

IPR004839
type: Resource
database: InterPro
comment: Aminotransferase_I/II

IPR004723
type: Resource
database: InterPro
comment: AONS_Archaea/Proteobacteria

IPR022834
type: Resource
database: InterPro
comment: AONS_Proteobacteria

IPR015424
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase

IPR015421
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_major

IPR015422
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_small

PTHR13693:SF100
type: Resource
database: PANTHER
comment: 8-AMINO-7-OXONONANOATE SYNTHASE
signature sequence match: PANTHER PTHR13693:SF100 match 1

PTHR13693
type: Resource
database: PANTHER
comment: CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE
signature sequence match: PANTHER PTHR13693 match 1

PF00155
type: Resource
database: Pfam
comment: Aminotran_1_2
signature sequence match: Pfam PF00155 match 1

SSF53383
type: Resource
database: SUPFAM
comment: PLP-dependent transferases
signature sequence match: SUPFAM SSF53383 match 1

TIGR00858
type: Resource
database: TIGRFAMs
comment: bioF
signature sequence match: TIGRFAMs TIGR00858 match 1

PS00599
type: Resource
database: PROSITE
comment: AA_TRANSFER_CLASS_2
signature sequence match: PROSITE PS00599 match 1

SIPD7ADB99A00D2D6E0
type: Structured Name
full name: 8-amino-7-oxononanoate synthase
short name: AONS
ec name: 2.3.1.47

SIP6AA432A4A9DA7749
type: Structured Name
full name: 7-keto-8-amino-pelargonic acid synthase
short name: 7-KAP synthase
short name: KAPA synthase

SIPD3A475FA85257690
type: Structured Name
full name: 8-amino-7-ketopelargonate synthase

bioF
type: Gene
locus name: AFE_0243

SIP19C555523742FF25
type: Function Annotation
comment: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.

SIPEC5778632C099B40
type: Subunit Annotation
comment: Homodimer.

SIP20E518F6518089AB
type: Similarity Annotation
comment: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

PRO_0000380885
type: Chain Annotation
comment: 8-amino-7-oxononanoate synthase
mass: 41748
range: 18638140291495726tt1tt389

18638140291495726tt1
type: Position
type: ExactPosition
position: 1
reference: B7J3Y7-1

18638140291495726tt389
type: Position
type: ExactPosition
position: 389
reference: B7J3Y7-1

18638140291495726tt23
type: Position
type: ExactPosition
position: 23
reference: B7J3Y7-1

18638140291495726tt114
type: Position
type: ExactPosition
position: 114
reference: B7J3Y7-1

18638140291495726tt115
type: Position
type: ExactPosition
position: 115
reference: B7J3Y7-1

18638140291495726tt139
type: Position
type: ExactPosition
position: 139
reference: B7J3Y7-1

18638140291495726tt185
type: Position
type: ExactPosition
position: 185
reference: B7J3Y7-1

18638140291495726tt213
type: Position
type: ExactPosition
position: 213
reference: B7J3Y7-1

18638140291495726tt242
type: Position
type: ExactPosition
position: 242
reference: B7J3Y7-1

18638140291495726tt357
type: Position
type: ExactPosition
position: 357
reference: B7J3Y7-1

SIP35410EBC1DE5CAC3
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18638140291495726tt245tt245

18638140291495726tt245
type: Position
type: ExactPosition
position: 245
reference: B7J3Y7-1

substrate

B7J3Y7-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 41748
value: MHSEREESWRAELSALRAHDLWRELQVLQPAPERGPPTFVGTRGEPLLSFASNDYLGLSAESALRDAAIAEIQQSGVGAGAAPLLGGERPAHAVLANALARWLGVEAALLFGSGYLANLGVISTLVGRGDRVYADRLNHASLVDGVRLSGARLHRYRHGDMTHLAQWLERGGRGQAWIITDGVFSMDGDIAPLPELATLAQQYGAGIILDEAHAFGVLGTEGQGTAAHWNMDIHGVDVIMGTLGKAFGVYGAFVAGSQDVVDLLRNRARSFIYHTALPSALAAAALVALDLLRHGDARRERLTQHRQHLRAQVPDAPWLASETPIQGLLLGDARRALTVSAQLRRAGLYCPAVRPPTVPADSARLRITLSAAHSHDDIELLATTLREVL

http://purl.uniprot.org/uniprot/B7J3Y7#attribution-FA5D98A901B748BD469A88B44E346004
manual: true
evidence: ECO_0000255
source: MF_01693

B5ELF7
type: Protein
reviewed: true
created: 2009-07-28
modified: 2023-05-03
version: 79
mnemonic: BIOF_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPD7ADB99A00D2D6E0
alternative name: SIP6AA432A4A9DA7749
alternative name: SIPD3A475FA85257690
enzyme: http://purl.uniprot.org/enzyme/2.3.1.47
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPBB63CBF15952CFE1
annotation: SIPAE0A5EAFBB70DD29
annotation: SIPC130AC129620C3DA
annotation: SIP7E4D9DEB567F11FA
annotation: SIP4C7A47016473C63F
annotation: SIPEAFA7697331CCB6D
annotation: PRO_0000380886
annotation: SIP8971584EC8C041BB
annotation: SIPF2D364BF49355E2C
annotation: SIPD95C88F0F94CD635
annotation: SIP47F94A696281589A
annotation: SIP0B3C6C44B457027C
annotation: SIPD6FC0C0804C61FFC
annotation: SIPA580847CAE23AA50
annotation: SIP26110E1F1C9BEB91
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/93
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0008710
classified with: GO_0030170
classified with: GO_0009102
sequence: B5ELF7-1

B5ELF7-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPD7ADB99A00D2D6E0
type: Structured Name
full name: 8-amino-7-oxononanoate synthase
short name: AONS
ec name: 2.3.1.47

SIP6AA432A4A9DA7749
type: Structured Name
full name: 7-keto-8-amino-pelargonic acid synthase
short name: 7-KAP synthase
short name: KAPA synthase

SIPD3A475FA85257690
type: Structured Name
full name: 8-amino-7-ketopelargonate synthase

bioF
type: Gene
locus name: Lferr_0419

SIPBB63CBF15952CFE1
type: Function Annotation
comment: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.

SIP4C7A47016473C63F
type: Subunit Annotation
comment: Homodimer.

SIPEAFA7697331CCB6D
type: Similarity Annotation
comment: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

PRO_0000380886
type: Chain Annotation
comment: 8-amino-7-oxononanoate synthase
mass: 41748
range: 18635920211588910tt1tt389

18635920211588910tt1
type: Position
type: ExactPosition
position: 1
reference: B5ELF7-1

18635920211588910tt389
type: Position
type: ExactPosition
position: 389
reference: B5ELF7-1

18635920211588910tt23
type: Position
type: ExactPosition
position: 23
reference: B5ELF7-1

18635920211588910tt114
type: Position
type: ExactPosition
position: 114
reference: B5ELF7-1

18635920211588910tt115
type: Position
type: ExactPosition
position: 115
reference: B5ELF7-1

18635920211588910tt139
type: Position
type: ExactPosition
position: 139
reference: B5ELF7-1

18635920211588910tt185
type: Position
type: ExactPosition
position: 185
reference: B5ELF7-1

18635920211588910tt213
type: Position
type: ExactPosition
position: 213
reference: B5ELF7-1

18635920211588910tt242
type: Position
type: ExactPosition
position: 242
reference: B5ELF7-1

18635920211588910tt357
type: Position
type: ExactPosition
position: 357
reference: B5ELF7-1

SIP26110E1F1C9BEB91
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18635920211588910tt245tt245

18635920211588910tt245
type: Position
type: ExactPosition
position: 245
reference: B5ELF7-1

substrate

B5ELF7-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 41748
value: MHSEREESWRAELSALRAHDLWRELQVLQPAPERGPPTFVGTRGEPLLSFASNDYLGLSAESALRDAAIAEIQQSGVGAGAAPLLGGERPAHAVLANALARWLGVEAALLFGSGYLANLGVISTLVGRGDRVYADRLNHASLVDGVRLSGARLHRYRHGDMTHLAQWLERGGRGQAWIITDGVFSMDGDIAPLPELATLAQQYGAGIILDEAHAFGVLGTEGQGTAAHWNMDIHGVDVIMGTLGKAFGVYGAFVAGSQDVVDLLRNRARSFIYHTALPSALAAAALVALDLLRHGDARRERLTQHRQHLRAQVPDAPWLASETPIQGLLLGDARRALTVSAQLRRAGLYCPAVRPPTVPADSARLRITLSAAHSHDDIELLATTLREVL

http://purl.uniprot.org/uniprot/B5ELF7#attribution-FA5D98A901B748BD469A88B44E346004
manual: true
evidence: ECO_0000255
source: MF_01693

B7J562
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 66
mnemonic: CH10_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPFDB43817E50FCF12
alternative name: SIP2774763869FB9103
alternative name: SIP5D535EA69F0EC691
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPC5023704368A9B88
annotation: SIPF447E3BAEF67E3C2
annotation: SIP2A1B6C419EB30FC6
annotation: SIPB3D2FC2A8293CCF2
annotation: PRO_1000129615
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0044183
sequence: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK
proteome: Chromosome

B7J562-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0234
type: Resource
database: eggNOG
comment: Bacteria

cd00320
type: Resource
database: CDD
comment: cpn10
signature sequence match: CDD cd00320 match 1

http://purl.uniprot.org/gene3d/2.30.33.40
type: Resource
database: Gene3D
comment: GroES chaperonin
signature sequence match: Gene3D 2.30.33.40 match 1

MF_00580
type: Resource
database: HAMAP
comment: CH10
signature sequence match: HAMAP MF 00580 match 1

IPR020818
type: Resource
database: InterPro
comment: Chaperonin_GroES

IPR037124
type: Resource
database: InterPro
comment: Chaperonin_GroES_sf

IPR018369
type: Resource
database: InterPro
comment: Chaprnonin_Cpn10_CS

IPR011032
type: Resource
database: InterPro
comment: GroES-like_sf

PTHR10772:SF58
type: Resource
database: PANTHER
comment: 10 KDA CHAPERONIN
signature sequence match: PANTHER PTHR10772:SF58 match 1

PTHR10772
type: Resource
database: PANTHER
comment: 10 KDA HEAT SHOCK PROTEIN
signature sequence match: PANTHER PTHR10772 match 1

PF00166
type: Resource
database: Pfam
comment: Cpn10
signature sequence match: Pfam PF00166 match 1

PR00297
type: Resource
database: PRINTS
comment: CHAPERONIN10

SM00883
type: Resource
database: SMART
comment: Cpn10
signature sequence match: SMART SM00883 match 1

SSF50129
type: Resource
database: SUPFAM
comment: GroES-like
signature sequence match: SUPFAM SSF50129 match 1

PS00681
type: Resource
database: PROSITE
comment: CHAPERONINS_CPN10
signature sequence match: PROSITE PS00681 match 1

SIPFDB43817E50FCF12
type: Structured Name
full name: Co-chaperonin GroES

SIP2774763869FB9103
type: Structured Name
full name: 10 kDa chaperonin

SIP5D535EA69F0EC691
type: Structured Name
full name: Chaperonin-10
short name: Cpn10

groES
type: Gene
alternative label: groS
locus name: AFE_0543

SIPC5023704368A9B88
type: Function Annotation
comment: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

SIPF447E3BAEF67E3C2
type: Subunit Annotation
comment: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.

SIPB3D2FC2A8293CCF2
type: Similarity Annotation
comment: Belongs to the GroES chaperonin family.

PRO_1000129615
type: Chain Annotation
comment: Co-chaperonin GroES
mass: 10675
range: 18638140322755118tt1tt96

18638140322755118tt1
type: Position
type: ExactPosition
position: 1
reference: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK

18638140322755118tt96
type: Position
type: ExactPosition
position: 96
reference: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK

MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 10675

http://purl.uniprot.org/uniprot/B7J562#attribution-BE67A4551C804FD86CAC41C18705626C
manual: true
evidence: ECO_0000255
source: MF_00580

B5EN20
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 67
mnemonic: CH10_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPFDB43817E50FCF12
alternative name: SIP2774763869FB9103
alternative name: SIP5D535EA69F0EC691
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP8252357B4C89D6C4
annotation: SIP02AE5A0D71CACC0B
annotation: SIP453C0CFBE3E4A2AC
annotation: SIPDEBAE7C847B0F3BB
annotation: PRO_1000129616
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0044183
sequence: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK

B5EN20-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPFDB43817E50FCF12
type: Structured Name
full name: Co-chaperonin GroES

SIP2774763869FB9103
type: Structured Name
full name: 10 kDa chaperonin

SIP5D535EA69F0EC691
type: Structured Name
full name: Chaperonin-10
short name: Cpn10

groES
type: Gene
alternative label: groS
locus name: Lferr_0699

SIP8252357B4C89D6C4
type: Function Annotation
comment: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

SIP02AE5A0D71CACC0B
type: Subunit Annotation
comment: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.

SIPDEBAE7C847B0F3BB
type: Similarity Annotation
comment: Belongs to the GroES chaperonin family.

PRO_1000129616
type: Chain Annotation
comment: Co-chaperonin GroES
mass: 10675
range: 18635920243830830tt1tt96

18635920243830830tt1
type: Position
type: ExactPosition
position: 1
reference: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK

18635920243830830tt96
type: Position
type: ExactPosition
position: 96
reference: MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK

MKLRPLHDRVVIRRLEEEQKTAGGIIIPDTAKEKPVRGEIVAAGHGKILEDGKVRALDVKTGDQVLFAKYAGTEIKVEGEELLVMREDDIMAVIEK
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 10675

http://purl.uniprot.org/uniprot/B5EN20#attribution-BE67A4551C804FD86CAC41C18705626C
manual: true
evidence: ECO_0000255
source: MF_00580

B7J561
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 70
mnemonic: CH60_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPF255B4347D4E348A
alternative name: SIPE5C33196A30979CA
alternative name: SIPE325E657B082D974
enzyme: http://purl.uniprot.org/enzyme/5.6.1.7
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP50B993CC19592D2A
annotation: SIPC789C35D1B1BF539
annotation: SIPEB3BE83F36056264
annotation: SIPFABED432CF6BEDF0
annotation: SIPB1F598B7D0A5AAF6
annotation: PRO_1000129962
annotation: SIP9415ADFBA2C2B226
annotation: SIP0A9F643869149528
annotation: SIP7F5BF6C2F4358B5E
annotation: SIP24D27E47AA1BC774
annotation: SIPE55C06B8E8783AF1
annotation: SIPA97C2CBB54C5E618
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0140662
classified with: GO_0016853
classified with: GO_0051082
classified with: GO_0042026
sequence: B7J561-1
proteome: Chromosome

B7J561-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0459
type: Resource
database: eggNOG
comment: Bacteria

cd03344
type: Resource
database: CDD
comment: GroEL
signature sequence match: CDD cd03344 match 1

http://purl.uniprot.org/gene3d/3.50.7.10
type: Resource
database: Gene3D
comment: GroEL
signature sequence match: Gene3D 3.50.7.10 match 1

http://purl.uniprot.org/gene3d/1.10.560.10
type: Resource
database: Gene3D
comment: GroEL-like equatorial domain
signature sequence match: Gene3D 1.10.560.10 match 1

http://purl.uniprot.org/gene3d/3.30.260.10
type: Resource
database: Gene3D
comment: TCP-1-like chaperonin intermediate domain
signature sequence match: Gene3D 3.30.260.10 match 1

MF_00600
type: Resource
database: HAMAP
comment: CH60
signature sequence match: HAMAP MF 00600 match 1

IPR018370
type: Resource
database: InterPro
comment: Chaperonin_Cpn60_CS

IPR001844
type: Resource
database: InterPro
comment: Cpn60/GroEL

IPR002423
type: Resource
database: InterPro
comment: Cpn60/GroEL/TCP-1

IPR027409
type: Resource
database: InterPro
comment: GroEL-like_apical_dom_sf

IPR027413
type: Resource
database: InterPro
comment: GROEL-like_equatorial_sf

IPR027410
type: Resource
database: InterPro
comment: TCP-1-like_intermed_sf

PTHR45633
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633 match 1

PTHR45633:SF3
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633:SF3 match 1

PF00118
type: Resource
database: Pfam
comment: Cpn60_TCP1
signature sequence match: Pfam PF00118 match 1

PR00298
type: Resource
database: PRINTS
comment: CHAPERONIN60

SSF52029
type: Resource
database: SUPFAM
comment: GroEL apical domain-like
signature sequence match: SUPFAM SSF52029 match 1

SSF48592
type: Resource
database: SUPFAM
comment: GroEL equatorial domain-like
signature sequence match: SUPFAM SSF48592 match 1

SSF54849
type: Resource
database: SUPFAM
comment: GroEL-intermediate domain like
signature sequence match: SUPFAM SSF54849 match 1

TIGR02348
type: Resource
database: TIGRFAMs
comment: GroEL
signature sequence match: TIGRFAMs TIGR02348 match 1

PS00296
type: Resource
database: PROSITE
comment: CHAPERONINS_CPN60
signature sequence match: PROSITE PS00296 match 1

SIPF255B4347D4E348A
type: Structured Name
full name: Chaperonin GroEL
ec name: 5.6.1.7

SIPE5C33196A30979CA
type: Structured Name
full name: 60 kDa chaperonin

SIPE325E657B082D974
type: Structured Name
full name: Chaperonin-60
short name: Cpn60

groEL
type: Gene
alternative label: groL
locus name: AFE_0542

SIP50B993CC19592D2A
type: Function Annotation
comment: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

SIPEB3BE83F36056264
type: Subunit Annotation
comment: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

SIPB1F598B7D0A5AAF6
type: Similarity Annotation
comment: Belongs to the chaperonin (HSP60) family.

PRO_1000129962
type: Chain Annotation
comment: Chaperonin GroEL
mass: 58631
range: 18638140322754862tt1tt551

18638140322754862tt1
type: Position
type: ExactPosition
position: 1
reference: B7J561-1

18638140322754862tt551
type: Position
type: ExactPosition
position: 551
reference: B7J561-1

18638140322754862tt30
type: Position
type: ExactPosition
position: 30
reference: B7J561-1

18638140322754862tt33
type: Position
type: ExactPosition
position: 33
reference: B7J561-1

18638140322754862tt51
type: Position
type: ExactPosition
position: 51
reference: B7J561-1

18638140322754862tt87
type: Position
type: ExactPosition
position: 87
reference: B7J561-1

18638140322754862tt91
type: Position
type: ExactPosition
position: 91
reference: B7J561-1

18638140322754862tt415
type: Position
type: ExactPosition
position: 415
reference: B7J561-1

18638140322754862tt479
type: Position
type: ExactPosition
position: 479
reference: B7J561-1

18638140322754862tt481
type: Position
type: ExactPosition
position: 481
reference: B7J561-1

18638140322754862tt495
type: Position
type: ExactPosition
position: 495
reference: B7J561-1

B7J561-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 58631
value: MPAKQVAFAEHAREKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASQASDEAGDGTTTATVLAQAIIREGLKAVIAGMNPMDLKRGIDKSVIVVVEELKKQSKPCKTQKEVAQVGTISANSDDSIGKIIAEAMEKVGNEGVITVEEGSGLANELDVVEGMQFDRGYLSPYFVNNQDKMVAELENPYILLHDKKISSIRDMLPILEQVAKSSRPLLIVAEDVEGEALATLVVNTMRGIIKVAAVKAPGFGDRRKAMLEDMAILTGGRVVSEEIGMKLESTTLADLGQAKKIVIDKENTTMIDGAGQQSEIKARVEQIRRQMEDASSDYDREKLQERVAKLAGGVAVIKVGAGSEMEMKEKKARVEDALHATRAAVEEGIVPGGGVALVRARHALEGFKTANHDQDMGVAIIRRAIEEPLRQIVANAGGEGSVVLNKVVDGKDGYGYNAATDEYGDMFEMGVIDPTKVTRTALQKASSIAGLMITTEAMVTELPKKDDKSGGDMGDMGGGMGGMGGMGGF

http://purl.uniprot.org/uniprot/B7J561#attribution-2F1A0E67B478851653C1AADDD6958B54
manual: true
evidence: ECO_0000255
source: MF_00600

B5EN19
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 71
mnemonic: CH60_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPF255B4347D4E348A
alternative name: SIPE5C33196A30979CA
alternative name: SIPE325E657B082D974
enzyme: http://purl.uniprot.org/enzyme/5.6.1.7
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP1288E792D0DC4594
annotation: SIP09FCED8CED3C3B3D
annotation: SIPD234B82E2A89895D
annotation: SIPBA1BF3FE16F93E43
annotation: SIP5D9C3A234581A023
annotation: PRO_1000129963
annotation: SIP94138B61F5001976
annotation: SIP92F72CD0528677EB
annotation: SIP3185F6E2303AC0AF
annotation: SIP8B956DDFD3BF4F53
annotation: SIP5ED88526E39B8547
annotation: SIP850670B3C7F6BA0E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0140662
classified with: GO_0016853
classified with: GO_0051082
classified with: GO_0042026
sequence: B5EN19-1

B5EN19-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPF255B4347D4E348A
type: Structured Name
full name: Chaperonin GroEL
ec name: 5.6.1.7

SIPE5C33196A30979CA
type: Structured Name
full name: 60 kDa chaperonin

SIPE325E657B082D974
type: Structured Name
full name: Chaperonin-60
short name: Cpn60

groEL
type: Gene
alternative label: groL
locus name: Lferr_0698

SIP1288E792D0DC4594
type: Function Annotation
comment: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

SIPD234B82E2A89895D
type: Subunit Annotation
comment: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

SIP5D9C3A234581A023
type: Similarity Annotation
comment: Belongs to the chaperonin (HSP60) family.

PRO_1000129963
type: Chain Annotation
comment: Chaperonin GroEL
mass: 58631
range: 18635920243767598tt1tt551

18635920243767598tt1
type: Position
type: ExactPosition
position: 1
reference: B5EN19-1

18635920243767598tt551
type: Position
type: ExactPosition
position: 551
reference: B5EN19-1

18635920243767598tt30
type: Position
type: ExactPosition
position: 30
reference: B5EN19-1

18635920243767598tt33
type: Position
type: ExactPosition
position: 33
reference: B5EN19-1

18635920243767598tt51
type: Position
type: ExactPosition
position: 51
reference: B5EN19-1

18635920243767598tt87
type: Position
type: ExactPosition
position: 87
reference: B5EN19-1

18635920243767598tt91
type: Position
type: ExactPosition
position: 91
reference: B5EN19-1

18635920243767598tt415
type: Position
type: ExactPosition
position: 415
reference: B5EN19-1

18635920243767598tt479
type: Position
type: ExactPosition
position: 479
reference: B5EN19-1

18635920243767598tt481
type: Position
type: ExactPosition
position: 481
reference: B5EN19-1

18635920243767598tt495
type: Position
type: ExactPosition
position: 495
reference: B5EN19-1

B5EN19-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 58631
value: MPAKQVAFAEHAREKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASQASDEAGDGTTTATVLAQAIIREGLKAVIAGMNPMDLKRGIDKSVIVVVEELKKQSKPCKTQKEVAQVGTISANSDDSIGKIIAEAMEKVGNEGVITVEEGSGLANELDVVEGMQFDRGYLSPYFVNNQDKMVAELENPYILLHDKKISSIRDMLPILEQVAKSSRPLLIVAEDVEGEALATLVVNTMRGIIKVAAVKAPGFGDRRKAMLEDMAILTGGRVVSEEIGMKLESTTLADLGQAKKIVIDKENTTMIDGAGQQSEIKARVEQIRRQMEDASSDYDREKLQERVAKLAGGVAVIKVGAGSEMEMKEKKARVEDALHATRAAVEEGIVPGGGVALVRARHALEGFKTANHDQDMGVAIIRRAIEEPLRQIVANAGGEGSVVLNKVVDGKDGYGYNAATDEYGDMFEMGVIDPTKVTRTALQKASSIAGLMITTEAMVTELPKKDDKSGGDMGDMGGGMGGMGGMGGF

http://purl.uniprot.org/uniprot/B5EN19#attribution-2F1A0E67B478851653C1AADDD6958B54
manual: true
evidence: ECO_0000255
source: MF_00600

P29134
type: Protein
reviewed: true
created: 1992-12-01
modified: 2023-05-03
version: 68
mnemonic: CH60_ACIFR
old mnemonic: CH60_THIFE
citation: http://purl.uniprot.org/citations/1360930
citation: http://purl.uniprot.org/citations/9026439
recommended name: SIPF255B4347D4E348A
alternative name: SIPE5C33196A30979CA
alternative name: SIPE325E657B082D974
enzyme: http://purl.uniprot.org/enzyme/5.6.1.7
organism: http://purl.uniprot.org/taxonomy/920
annotation: SIP01A930C6FE962CE8
annotation: SIP2F1AE808063B52EC
annotation: SIP061B6F8FA9A37448
annotation: SIPBB350DABA1F2FEEE
annotation: SIP52316E0FDDC925EF
annotation: SIP5C2FF073EEDEC081
annotation: SIPC23DAA3B449555E3
annotation: PRO_0000063585
annotation: SIPD5D716C6E633E850
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/903
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/346
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0016853
sequence: PAKQVAFAEHAREKMLRGVNVLA

P29134-citation-1360930
type: Citation Statement
scope: PROTEIN SEQUENCE

ATCC 19859 / BCRC 13033 / JCM 3863 / NCIMB 9490
type: Strain

P29134-citation-9026439
type: Citation Statement
scope: PHOSPHORYLATION

SIPF255B4347D4E348A
type: Structured Name
full name: Chaperonin GroEL
ec name: 5.6.1.7

SIPE5C33196A30979CA
type: Structured Name
full name: 60 kDa chaperonin

SIPE325E657B082D974
type: Structured Name
full name: Chaperonin-60
short name: Cpn60

groEL
type: Gene
alternative label: groL
alternative label: mopA

SIP01A930C6FE962CE8
type: Function Annotation
comment: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

SIP061B6F8FA9A37448
type: Subunit Annotation
comment: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

SIP52316E0FDDC925EF
type: Induction Annotation
comment: By heat shock.

SIP5C2FF073EEDEC081
type: PTM Annotation
comment: Phosphorylated on threonine.

SIPC23DAA3B449555E3
type: Similarity Annotation
comment: Belongs to the chaperonin (HSP60) family.

PRO_0000063585
type: Chain Annotation
comment: Chaperonin GroEL
mass: 2536
range: 22573219356816430tt1tf23

22573219356816430tt1
type: Position
type: ExactPosition
position: 1
reference: PAKQVAFAEHAREKMLRGVNVLA

22573219356816430tt23
type: Position
type: ExactPosition
position: 23
reference: PAKQVAFAEHAREKMLRGVNVLA

PAKQVAFAEHAREKMLRGVNVLA
type: Simple Sequence
modified: 1992-12-01
version: 1
fragment: single
mass: 2536

http://purl.uniprot.org/uniprot/P29134#attribution-2F1A0E67B478851653C1AADDD6958B54
manual: true
evidence: ECO_0000255
source: MF_00600

http://purl.uniprot.org/uniprot/P29134#attribution-ECCDA4D1C036CEE7A0F63728CB2AFFC4
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/9026439

http://purl.uniprot.org/uniprot/P29134#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

P51045
type: Protein
reviewed: true
created: 1996-10-01
modified: 2023-05-03
version: 90
mnemonic: CISY_ACIFI
old mnemonic: CISY_ACIFR
old mnemonic: CISY_THIFE
citation: http://purl.uniprot.org/citations/8828222
recommended name: SIP0CC0E185EA58BFB7
enzyme: http://purl.uniprot.org/enzyme/2.3.3.16
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP196D6CDC3EEBEE74
annotation: SIP4AC45CD537F474DF
annotation: SIP8BBC7C4B078E909B
annotation: SIPC3760D15E1A2ECBF
annotation: PRO_0000169975
annotation: SIPF3E6E0312CBA7049
annotation: SIP3E1603850A459A90
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/816
classified with: GO_0005737
classified with: GO_0036440
classified with: GO_0006099
sequence: P51045-1

P51045-citation-8828222
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

cd06112
type: Resource
database: CDD
comment: citrate_synt_like_1_1
signature sequence match: CDD cd06112 match 1

http://purl.uniprot.org/gene3d/1.10.580.10
type: Resource
database: Gene3D
comment: Citrate Synthase, domain 1
signature sequence match: Gene3D 1.10.580.10 match 1

http://purl.uniprot.org/gene3d/1.10.230.10
type: Resource
database: Gene3D
comment: Cytochrome P450-Terp, domain 2
signature sequence match: Gene3D 1.10.230.10 match 1

IPR011278
type: Resource
database: InterPro
comment: 2-MeCitrate/Citrate_synth_II

IPR016142
type: Resource
database: InterPro
comment: Citrate_synth-like_lrg_a-sub

IPR016143
type: Resource
database: InterPro
comment: Citrate_synth-like_sm_a-sub

IPR002020
type: Resource
database: InterPro
comment: Citrate_synthase

IPR019810
type: Resource
database: InterPro
comment: Citrate_synthase_AS

IPR024176
type: Resource
database: InterPro
comment: Citrate_synthase_bac-typ

IPR036969
type: Resource
database: InterPro
comment: Citrate_synthase_sf

PTHR11739
type: Resource
database: PANTHER
comment: CITRATE SYNTHASE
signature sequence match: PANTHER PTHR11739 match 1

PTHR11739:SF4
type: Resource
database: PANTHER
comment: CITRATE SYNTHASE, PEROXISOMAL
signature sequence match: PANTHER PTHR11739:SF4 match 1

PF00285
type: Resource
database: Pfam
comment: Citrate_synt
signature sequence match: Pfam PF00285 match 1

PIRSF001369
type: Resource
database: PIRSF
comment: Citrate_synth
signature sequence match: PIRSF PIRSF001369 match 1

PR00143
type: Resource
database: PRINTS
comment: CITRTSNTHASE

SSF48256
type: Resource
database: SUPFAM
comment: Citrate synthase
signature sequence match: SUPFAM SSF48256 match 1

TIGR01800
type: Resource
database: TIGRFAMs
comment: cit_synth_II
signature sequence match: TIGRFAMs TIGR01800 match 1

PS00480
type: Resource
database: PROSITE
comment: CITRATE_SYNTHASE
signature sequence match: PROSITE PS00480 match 1

SIP0CC0E185EA58BFB7
type: Structured Name
full name: Citrate synthase
ec name: 2.3.3.16

gltA
type: Gene

SIP8BBC7C4B078E909B
type: Annotation
comment: Citrate synthase is found in nearly all cells capable of oxidative metabolism.

SIPC3760D15E1A2ECBF
type: Similarity Annotation
comment: Belongs to the citrate synthase family.

PRO_0000169975
type: Chain Annotation
comment: Citrate synthase
mass: 42689
range: 22576483515249966tt1tt386

22576483515249966tt1
type: Position
type: ExactPosition
position: 1
reference: P51045-1

22576483515249966tt386
type: Position
type: ExactPosition
position: 386
reference: P51045-1

22576483515249966tt266
type: Position
type: ExactPosition
position: 266
reference: P51045-1

22576483515249966tt322
type: Position
type: ExactPosition
position: 322
reference: P51045-1

P51045-1
type: Simple Sequence
modified: 1996-10-01
version: 1
mass: 42689
value: MAEPNFAPGLEGVAATQSSISNIDGAAGLLSYRGFAIADLAAHSSFEEVALLLLDGVLPGAADLERFDHGLRAHRQVKYNVREIMKFMPVTGHPMDMLHCAVASLGMFYPQQELSDAERGNTLHLDAMAMRIIARMPTIVAMWEQMRFGNDPISPRPDLSHAANFLYMLSGREPDPAHTKILDSCLILHAEHTINASTFSVLVTGSTLTNPYHVIGGAIGTLAGPLHGGANQKVVEMLEEISSVQQVGAYLDRKMANKEKIWGFGHRIYKTRDPRAVILKGMMEDMASHGNLRHSSLFEIAIEVERQATERLGAQGIHANVDFYSGVLYHEMGIKADLFTPIFAMARSAGWLAHWREQLADNRIFRPTQVYTGEQDRRYVPVAQRT

http://purl.uniprot.org/uniprot/P51045#attribution-490D07EB864C312F8B2ACA8AA0E742D6
manual: true
evidence: ECO_0000255
source: PRU10117

http://purl.uniprot.org/uniprot/P51045#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B7J791
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 78
mnemonic: CLPX_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPF43CC31C6B90A8EC
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP2F0169F9EB73924A
annotation: SIP997D47444A6687B8
annotation: SIPCBB33544DB237BAC
annotation: PRO_1000189672
annotation: SIP27057F58460D6107
annotation: SIPB2870C4E76B46C41
annotation: SIPA36F5541D30336AD
annotation: SIPA3C4B955B643145F
annotation: SIP5B0C78ED64C014DC
annotation: SIP07DA67774885CEB1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0046983
classified with: GO_0051082
classified with: GO_0008270
sequence: B7J791-1
proteome: Chromosome

B7J791-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG1219
type: Resource
database: eggNOG
comment: Bacteria

cd19497
type: Resource
database: CDD
comment: RecA-like_ClpX
signature sequence match: CDD cd19497 match 1

http://purl.uniprot.org/gene3d/6.20.220.10
type: Resource
database: Gene3D
comment: ClpX chaperone, C4-type zinc finger domain
signature sequence match: Gene3D 6.20.220.10 match 1

MF_00175
type: Resource
database: HAMAP
comment: ClpX
signature sequence match: HAMAP MF 00175 match 1

IPR003959
type: Resource
database: InterPro
comment: ATPase_AAA_core

IPR019489
type: Resource
database: InterPro
comment: Clp_ATPase_C

IPR004487
type: Resource
database: InterPro
comment: Clp_protease_ATP-bd_su_ClpX

IPR046425
type: Resource
database: InterPro
comment: ClpX_bact

IPR010603
type: Resource
database: InterPro
comment: Znf_CppX_C4

IPR038366
type: Resource
database: InterPro
comment: Znf_CppX_C4_sf

PTHR48102:SF7
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48102:SF7 match 1

PTHR48102
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED
signature sequence match: PANTHER PTHR48102 match 1

PF07724
type: Resource
database: Pfam
comment: AAA_2
signature sequence match: Pfam PF07724 match 1

PF10431
type: Resource
database: Pfam
comment: ClpB_D2-small
signature sequence match: Pfam PF10431 match 1

PF06689
type: Resource
database: Pfam
comment: zf-C4_ClpX
signature sequence match: Pfam PF06689 match 1

SM01086
type: Resource
database: SMART
comment: ClpB_D2-small
signature sequence match: SMART SM01086 match 1

SM00994
type: Resource
database: SMART
comment: zf-C4_ClpX
signature sequence match: SMART SM00994 match 1

SSF57716
type: Resource
database: SUPFAM
comment: Glucocorticoid receptor-like (DNA-binding domain)
signature sequence match: SUPFAM SSF57716 match 1

TIGR00382
type: Resource
database: TIGRFAMs
comment: clpX
signature sequence match: TIGRFAMs TIGR00382 match 1

PS51902
type: Resource
database: PROSITE
comment: CLPX_ZB
signature sequence match: PROSITE PS51902 match 1

SIPF43CC31C6B90A8EC
type: Structured Name
full name: ATP-dependent Clp protease ATP-binding subunit ClpX

clpX
type: Gene
locus name: AFE_0911

SIP2F0169F9EB73924A
type: Function Annotation
comment: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.

SIP997D47444A6687B8
type: Subunit Annotation
comment: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIPCBB33544DB237BAC
type: Similarity Annotation
comment: Belongs to the ClpX chaperone family.

PRO_1000189672
type: Chain Annotation
comment: ATP-dependent Clp protease ATP-binding subunit ClpX
mass: 46457
range: 18638140356505902tt1tt423

18638140356505902tt1
type: Position
type: ExactPosition
position: 1
reference: B7J791-1

18638140356505902tt423
type: Position
type: ExactPosition
position: 423
reference: B7J791-1

SIP27057F58460D6107
type: Domain Extent Annotation
comment: ClpX-type ZB
range: 18638140356505902tt3tt56

18638140356505902tt3
type: Position
type: ExactPosition
position: 3
reference: B7J791-1

18638140356505902tt56
type: Position
type: ExactPosition
position: 56
reference: B7J791-1

18638140356505902tt15
type: Position
type: ExactPosition
position: 15
reference: B7J791-1

18638140356505902tt18
type: Position
type: ExactPosition
position: 18
reference: B7J791-1

18638140356505902tt37
type: Position
type: ExactPosition
position: 37
reference: B7J791-1

18638140356505902tt40
type: Position
type: ExactPosition
position: 40
reference: B7J791-1

18638140356505902tt119
type: Position
type: ExactPosition
position: 119
reference: B7J791-1

18638140356505902tt126
type: Position
type: ExactPosition
position: 126
reference: B7J791-1

B7J791-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 46457
value: MAGKHEGSGEKTLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIVKDEILDDHSEAQDKLPKPMEIRKTLDDYVIGQDVAKKVLSVAVYNHYKRLEHGGKDNEVELDKSNILLIGPTGSGKTLLAQTLARLLNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQTGIVYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRHILFICGGAFAGLEKSVSARLEKGGMGFNAPLKRRDKEATAAMLMQNLEPEDLVRYGLIPEFVGRLPILALLEELDEEALISILTDPKNALVKQYQKLFALEGVTLEFRTEALRAIAKKALARKTGARGLRSILEQILLDTMYELPSMSGVKKVVVDAAVVESGTKPLLVYDDAAKVDMSHPA

http://purl.uniprot.org/uniprot/B7J791#attribution-CFB06F30A19C652E3C2E44B930DCAAA4
manual: true
evidence: ECO_0000255
source: MF_00175

http://purl.uniprot.org/uniprot/B7J791#attribution-53EBA6D767FE97D40C9959E24A2E919D
manual: true
evidence: ECO_0000255
source: PRU01250

B5EQ29
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 80
mnemonic: CLPX_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPF43CC31C6B90A8EC
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP7F0D7A9053B461DC
annotation: SIPA9AF54A9DCFF432F
annotation: SIP2AC22D15742493F8
annotation: PRO_1000189673
annotation: SIPD60063AB630E1002
annotation: SIPD0018B8A89C61989
annotation: SIP1347B4694EEA7F34
annotation: SIPC1798CE357FF7EF6
annotation: SIP888E6FC60DCEE278
annotation: SIP4F6C0EB1992EC665
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0046983
classified with: GO_0051082
classified with: GO_0008270
sequence: B5EQ29-1

B5EQ29-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPF43CC31C6B90A8EC
type: Structured Name
full name: ATP-dependent Clp protease ATP-binding subunit ClpX

clpX
type: Gene
locus name: Lferr_1032

SIP7F0D7A9053B461DC
type: Function Annotation
comment: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.

SIPA9AF54A9DCFF432F
type: Subunit Annotation
comment: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIP2AC22D15742493F8
type: Similarity Annotation
comment: Belongs to the ClpX chaperone family.

PRO_1000189673
type: Chain Annotation
comment: ATP-dependent Clp protease ATP-binding subunit ClpX
mass: 46457
range: 18635920294164782tt1tt423

18635920294164782tt1
type: Position
type: ExactPosition
position: 1
reference: B5EQ29-1

18635920294164782tt423
type: Position
type: ExactPosition
position: 423
reference: B5EQ29-1

SIPD60063AB630E1002
type: Domain Extent Annotation
comment: ClpX-type ZB
range: 18635920294164782tt3tt56

18635920294164782tt3
type: Position
type: ExactPosition
position: 3
reference: B5EQ29-1

18635920294164782tt56
type: Position
type: ExactPosition
position: 56
reference: B5EQ29-1

18635920294164782tt15
type: Position
type: ExactPosition
position: 15
reference: B5EQ29-1

18635920294164782tt18
type: Position
type: ExactPosition
position: 18
reference: B5EQ29-1

18635920294164782tt37
type: Position
type: ExactPosition
position: 37
reference: B5EQ29-1

18635920294164782tt40
type: Position
type: ExactPosition
position: 40
reference: B5EQ29-1

18635920294164782tt119
type: Position
type: ExactPosition
position: 119
reference: B5EQ29-1

18635920294164782tt126
type: Position
type: ExactPosition
position: 126
reference: B5EQ29-1

B5EQ29-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 46457
value: MAGKHEGSGEKTLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIVKDEILDDHSEAQDKLPKPMEIRKTLDDYVIGQDVAKKVLSVAVYNHYKRLEHGGKDNEVELDKSNILLIGPTGSGKTLLAQTLARLLNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQTGIVYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRHILFICGGAFAGLEKSVSARLEKGGMGFNAPLKRRDKEATAAMLMQNLEPEDLVRYGLIPEFVGRLPILALLEELDEEALISILTDPKNALVKQYQKLFALEGVTLEFRTEALRAIAKKALARKTGARGLRSILEQILLDTMYELPSMSGVKKVVVDAAVVESGTKPLLVYDDAAKVDMSHPA

http://purl.uniprot.org/uniprot/B5EQ29#attribution-CFB06F30A19C652E3C2E44B930DCAAA4
manual: true
evidence: ECO_0000255
source: MF_00175

http://purl.uniprot.org/uniprot/B5EQ29#attribution-53EBA6D767FE97D40C9959E24A2E919D
manual: true
evidence: ECO_0000255
source: PRU01250

B7J9Q0
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 73
mnemonic: CRCB_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP0E954245F7FA06E4
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP7D273414D8C33E01
annotation: SIPE7D452C9C1FF9E32
annotation: SIP8CBFF344704E21A4
annotation: PRO_1000189698
annotation: SIP7373D82D64CB5E86
annotation: SIPDAACA4EF5BA6EE69
annotation: SIPF540F825EE99C81F
annotation: SIP3D092192D8F1EE6C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/813
classified with: GO_0005886
classified with: GO_1903425
sequence: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST
proteome: Chromosome

B7J9Q0-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0239
type: Resource
database: eggNOG
comment: Bacteria

MF_00454
type: Resource
database: HAMAP
comment: CrcB
signature sequence match: HAMAP MF 00454 match 1

IPR003691
type: Resource
database: InterPro
comment: CrcB

PTHR28259
type: Resource
database: PANTHER
comment: FLUORIDE EXPORT PROTEIN 1-RELATED
signature sequence match: PANTHER PTHR28259 match 1

PTHR28259:SF1
type: Resource
database: PANTHER
comment: FLUORIDE EXPORT PROTEIN 1-RELATED
signature sequence match: PANTHER PTHR28259:SF1 match 1

PF02537
type: Resource
database: Pfam
comment: CRCB
signature sequence match: Pfam PF02537 match 1

TIGR00494
type: Resource
database: TIGRFAMs
comment: crcB
signature sequence match: TIGRFAMs TIGR00494 match 1

SIP0E954245F7FA06E4
type: Structured Name
full name: Putative fluoride ion transporter CrcB

crcB
type: Gene
locus name: AFE_2926

SIP7D273414D8C33E01
type: Function Annotation
comment: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

SIP8CBFF344704E21A4
type: Similarity Annotation
comment: Belongs to the CrcB (TC 9.B.71) family.

PRO_1000189698
type: Chain Annotation
comment: Putative fluoride ion transporter CrcB
mass: 13553
range: 18638140391632942tt1tt125

18638140391632942tt1
type: Position
type: ExactPosition
position: 1
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18638140391632942tt125
type: Position
type: ExactPosition
position: 125
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIP7373D82D64CB5E86
type: Transmembrane Annotation
comment: Helical
range: 18638140391632942tt1tt21

18638140391632942tt21
type: Position
type: ExactPosition
position: 21
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIPDAACA4EF5BA6EE69
type: Transmembrane Annotation
comment: Helical
range: 18638140391632942tt34tt54

18638140391632942tt34
type: Position
type: ExactPosition
position: 34
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18638140391632942tt54
type: Position
type: ExactPosition
position: 54
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIPF540F825EE99C81F
type: Transmembrane Annotation
comment: Helical
range: 18638140391632942tt72tt92

18638140391632942tt72
type: Position
type: ExactPosition
position: 72
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18638140391632942tt92
type: Position
type: ExactPosition
position: 92
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIP3D092192D8F1EE6C
type: Transmembrane Annotation
comment: Helical
range: 18638140391632942tt101tt121

18638140391632942tt101
type: Position
type: ExactPosition
position: 101
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18638140391632942tt121
type: Position
type: ExactPosition
position: 121
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 13553

http://purl.uniprot.org/uniprot/B7J9Q0#attribution-A584A86F444CAD9FA979C3404C4D5D6F
manual: true
evidence: ECO_0000255
source: MF_00454

B5EPU0
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 75
mnemonic: CRCB_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP0E954245F7FA06E4
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP02608A824409BE6E
annotation: SIP45D997D34B88AD33
annotation: SIPC4EF28A53E0DEC0B
annotation: PRO_1000189699
annotation: SIPEC02275E94F76CE8
annotation: SIPB4F0C01DB6AC9631
annotation: SIPD3156382C757A9CB
annotation: SIP0485BE02780A384B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/813
classified with: GO_0005886
classified with: GO_1903425
sequence: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

B5EPU0-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP0E954245F7FA06E4
type: Structured Name
full name: Putative fluoride ion transporter CrcB

crcB
type: Gene
locus name: Lferr_2541

SIP02608A824409BE6E
type: Function Annotation
comment: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

SIPC4EF28A53E0DEC0B
type: Similarity Annotation
comment: Belongs to the CrcB (TC 9.B.71) family.

PRO_1000189699
type: Chain Annotation
comment: Putative fluoride ion transporter CrcB
mass: 13553
range: 18635920279679022tt1tt125

18635920279679022tt1
type: Position
type: ExactPosition
position: 1
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18635920279679022tt125
type: Position
type: ExactPosition
position: 125
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIPEC02275E94F76CE8
type: Transmembrane Annotation
comment: Helical
range: 18635920279679022tt1tt21

18635920279679022tt21
type: Position
type: ExactPosition
position: 21
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIPB4F0C01DB6AC9631
type: Transmembrane Annotation
comment: Helical
range: 18635920279679022tt34tt54

18635920279679022tt34
type: Position
type: ExactPosition
position: 34
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18635920279679022tt54
type: Position
type: ExactPosition
position: 54
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIPD3156382C757A9CB
type: Transmembrane Annotation
comment: Helical
range: 18635920279679022tt72tt92

18635920279679022tt72
type: Position
type: ExactPosition
position: 72
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18635920279679022tt92
type: Position
type: ExactPosition
position: 92
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

SIP0485BE02780A384B
type: Transmembrane Annotation
comment: Helical
range: 18635920279679022tt101tt121

18635920279679022tt101
type: Position
type: ExactPosition
position: 101
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

18635920279679022tt121
type: Position
type: ExactPosition
position: 121
reference: MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST

MFATFGFIALFAVLGAWARYGQTLLVQAAFGRGFPWATLSINVLGCFLMGFLFFETLERISVSPELRTGMLTGGLGAYTTFSTFSLETLVLFENGEAVKGLLYMFTSLFLCVGAAFAGAWISHST
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 13553

http://purl.uniprot.org/uniprot/B5EPU0#attribution-A584A86F444CAD9FA979C3404C4D5D6F
manual: true
evidence: ECO_0000255
source: MF_00454

S5FT07
type: Protein
reviewed: true
created: 2018-09-12
modified: 2023-05-03
version: 25
mnemonic: CS2H1_ACITH
citation: http://purl.uniprot.org/citations/23836868
recommended name: SIP55EA5E640DAA335D
enzyme: http://purl.uniprot.org/enzyme/3.13.1.5
organism: http://purl.uniprot.org/taxonomy/930
annotation: SIP9B56F9F7180203C2
annotation: SIP1C15AA0C94EA391E
annotation: SIP79F610E73989F628
annotation: SIP6DD8E794AB4B61FD
annotation: SIP3CCD8D230C9FA1C5
annotation: SIP03EC8131D0B6ED53
annotation: SIP87FD38CB43B6E6D3
annotation: PRO_0000444999
annotation: SIP9185677FCBEB20F7
annotation: SIP7EA2C18434991E14
annotation: SIP954D92AB3AFAA4F8
annotation: SIPF1837C73065BD801
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0004089
classified with: GO_0016787
classified with: GO_0008270
classified with: GO_0070814
sequence: S5FT07-1

S5FT07-citation-23836868
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
scope: FUNCTION
scope: CATALYTIC ACTIVITY
scope: SUBSTRATE SPECIFICITY
scope: BIOPHYSICOCHEMICAL PROPERTIES
scope: SUBUNIT
scope: 3D-STRUCTURE MODELING
scope: PATHWAY

S1p
type: Strain

http://purl.uniprot.org/brenda/3.13.1.5
type: Resource
database: BRENDA
comment: 92

cd03379
type: Resource
database: CDD
comment: beta_CA_cladeD
signature sequence match: CDD cd03379 match 1

http://purl.uniprot.org/gene3d/3.40.1050.10
type: Resource
database: Gene3D
comment: Carbonic anhydrase
signature sequence match: Gene3D 3.40.1050.10 match 1

IPR001765
type: Resource
database: InterPro
comment: Carbonic_anhydrase

IPR036874
type: Resource
database: InterPro
comment: Carbonic_anhydrase_sf

PTHR43175:SF3
type: Resource
database: PANTHER
comment: CARBON DISULFIDE HYDROLASE
signature sequence match: PANTHER PTHR43175:SF3 match 1

PTHR43175
type: Resource
database: PANTHER
comment: CARBONIC ANHYDRASE
signature sequence match: PANTHER PTHR43175 match 1

PF00484
type: Resource
database: Pfam
comment: Pro_CA
signature sequence match: Pfam PF00484 match 1

SM00947
type: Resource
database: SMART
comment: Pro_CA
signature sequence match: SMART SM00947 match 1

SSF53056
type: Resource
database: SUPFAM
comment: beta-carbonic anhydrase, cab
signature sequence match: SUPFAM SSF53056 match 1

SIP55EA5E640DAA335D
type: Structured Name
full name: Carbon disulfide hydrolase
short name: CS(2) hydrolase
ec name: 3.13.1.5

csh
type: Gene

SIP9B56F9F7180203C2
type: Function Annotation
comment: Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate. Likely plays a key role in sulfur metabolism that allows A.thiooxidans S1p to grow on carbon disulfide as the main carbon and energy source. Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).

SIP79F610E73989F628
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP6DD8E794AB4B61FD
type: Kinetics Annotation
comment: kcat is 780 sec(-1) with carbon disulfide as substrate. kcat is 814 sec(-1) with the intermediate carbonyl sulfide as substrate.
measured affinity: 93 uM for carbon disulfide
measured affinity: 74 uM for carbonyl sulfide
measured activity: 32 nmol/min/ug enzyme towards hydrogen sulfide formation from carbon disulfide
measured activity: 34 nmol/min/ug enzyme towards hydrogen sulfide formation from carbonyl sulfide

SIP03EC8131D0B6ED53
type: Subunit Annotation
comment: Forms only homooctamers in solution.

SIP87FD38CB43B6E6D3
type: Similarity Annotation
comment: Belongs to the beta-class carbonic anhydrase family.

PRO_0000444999
type: Chain Annotation
comment: Carbon disulfide hydrolase
mass: 24317
range: 23420999243413294tt1tt217

23420999243413294tt1
type: Position
type: ExactPosition
position: 1
reference: S5FT07-1

23420999243413294tt217
type: Position
type: ExactPosition
position: 217
reference: S5FT07-1

SIP9185677FCBEB20F7
type: Region Annotation
comment: Disordered
range: 23420999243413294tt192tt217

23420999243413294tt192
type: Position
type: ExactPosition
position: 192
reference: S5FT07-1

23420999243413294tt39
type: Position
type: ExactPosition
position: 39
reference: S5FT07-1

23420999243413294tt98
type: Position
type: ExactPosition
position: 98
reference: S5FT07-1

23420999243413294tt101
type: Position
type: ExactPosition
position: 101
reference: S5FT07-1

S5FT07-1
type: Simple Sequence
modified: 2013-10-16
version: 1
mass: 24317
value: MSTLKEQLTAHVASYDHWAQRRRYGPDGHNNRSLWVLACMDERLPVDEALGIHVDTPAGGGDAHCFRNAGGIVTDDAIRSAMLTCNFFGTKEIVIVQHTQCGMLSGNANEMEKVLREKGMDTDNITLDPTLPELQLAKGAFAKWIGMMDDVDETCMKTINAFKNHPLIPKDIVVSGWVWEVENRRLRAPTLDKEKRARTDCTPTPYGVKGNQPPRWK

http://purl.uniprot.org/uniprot/S5FT07#attribution-90D4939E566A6E70F1403B34B96263A9
manual: true
evidence: ECO_0000250
source: G0WXL9

http://purl.uniprot.org/uniprot/S5FT07#attribution-0DB7A293AA6E380F443DD18BC34C17A8
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/23836868

http://purl.uniprot.org/uniprot/S5FT07#attribution-1C6500CAD0522AB6B9F59BDDCC10FE10
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/23836868

http://purl.uniprot.org/uniprot/S5FT07#attribution-8FACB4A0C3895B31B3B9691A25D284CB
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/S5FT07#attribution-83BD2F717DA0B54ACFCB0AF0882A1986
manual: true
evidence: ECO_0000312
source: AGQ48123.1

S5FU55
type: Protein
reviewed: true
created: 2018-09-12
modified: 2023-05-03
version: 25
mnemonic: CS2H2_ACITH
citation: http://purl.uniprot.org/citations/23836868
recommended name: SIP55EA5E640DAA335D
enzyme: http://purl.uniprot.org/enzyme/3.13.1.5
organism: http://purl.uniprot.org/taxonomy/930
annotation: SIP4E3426B25AF11138
annotation: SIP27C824C200A41960
annotation: SIP4B4D362C89D7278E
annotation: SIPCC15EB6C21805B6E
annotation: SIPFB3162F42F5FE331
annotation: SIPFE872B495EC4CA7E
annotation: SIP6C4D8E75D6AAF9A7
annotation: PRO_0000445000
annotation: SIP6E1630580AA55D6D
annotation: SIP82412D2EE2DF52BA
annotation: SIPBE7C259215F7AA47
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0004089
classified with: GO_0016787
classified with: GO_0008270
classified with: GO_0070814
sequence: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

S5FU55-citation-23836868
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
scope: FUNCTION
scope: CATALYTIC ACTIVITY
scope: SUBSTRATE SPECIFICITY
scope: BIOPHYSICOCHEMICAL PROPERTIES
scope: SUBUNIT
scope: 3D-STRUCTURE MODELING
scope: PATHWAY

G8
type: Strain

SIP55EA5E640DAA335D
type: Structured Name
full name: Carbon disulfide hydrolase
short name: CS(2) hydrolase
ec name: 3.13.1.5

csh
type: Gene

SIP4E3426B25AF11138
type: Function Annotation
comment: Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate. Likely plays a key role in sulfur metabolism that allows A.thiooxidans G8 to grow on carbon disulfide as the main carbon and energy source. Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).

SIP4B4D362C89D7278E
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIPCC15EB6C21805B6E
type: Kinetics Annotation
comment: kcat is 3000 sec(-1) with carbon disulfide as substrate. kcat is 22400 sec(-1) with the intermediate carbonyl sulfide as substrate.
measured affinity: 46 uM for carbon disulfide
measured affinity: 14 uM for carbonyl sulfide
measured activity: 131 nmol/min/ug enzyme towards hydrogen sulfide formation from carbon disulfide
measured activity: 97 nmol/min/ug enzyme towards hydrogen sulfide formation from carbonyl sulfide

SIPFE872B495EC4CA7E
type: Subunit Annotation
comment: Exists as both octamers and hexadecamers in solution. The hexadecameric homooligomer may form a catenane, through interactions of two interlocked octameric rings.

SIP6C4D8E75D6AAF9A7
type: Similarity Annotation
comment: Belongs to the beta-class carbonic anhydrase family.

PRO_0000445000
type: Chain Annotation
comment: Carbon disulfide hydrolase
mass: 22632
range: 23420999260517678tt1tt199

23420999260517678tt1
type: Position
type: ExactPosition
position: 1
reference: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

23420999260517678tt199
type: Position
type: ExactPosition
position: 199
reference: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

23420999260517678tt36
type: Position
type: ExactPosition
position: 36
reference: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

23420999260517678tt91
type: Position
type: ExactPosition
position: 91
reference: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

23420999260517678tt94
type: Position
type: ExactPosition
position: 94
reference: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK

MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK
type: Simple Sequence
modified: 2013-10-16
version: 1
mass: 22632

http://purl.uniprot.org/uniprot/S5FU55#attribution-90D4939E566A6E70F1403B34B96263A9
manual: true
evidence: ECO_0000250
source: G0WXL9

http://purl.uniprot.org/uniprot/S5FU55#attribution-0DB7A293AA6E380F443DD18BC34C17A8
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/23836868

http://purl.uniprot.org/uniprot/S5FU55#attribution-1C6500CAD0522AB6B9F59BDDCC10FE10
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/23836868

http://purl.uniprot.org/uniprot/S5FU55#attribution-8FACB4A0C3895B31B3B9691A25D284CB
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/S5FU55#attribution-D524C81DBF1CAF4F0B1C6B6B0B44359D
manual: true
evidence: ECO_0000312
source: AGQ48122.1

P74917
type: Protein
reviewed: true
created: 1997-11-01
modified: 2023-05-03
version: 118
mnemonic: CY552_ACIFI
old mnemonic: C552_THIFE
old mnemonic: CY552_ACIFR
old mnemonic: CY552_THIFE
citation: SIP4DFECD6624AD3A70
citation: http://purl.uniprot.org/citations/8973648
conflicting sequence: SIP097C334A225050D5
recommended name: SIP46E234A20120E7EA
alternative name: SIPC7C0ACF5683AB041
organism: http://purl.uniprot.org/taxonomy/1232575
annotation: SIP2FC41E6E4F984B4D
annotation: SIPF6A34B257051A47A
annotation: SIP56F6EA9C0678ECE6
annotation: SIP161A4F6CD4552737
annotation: SIP799FA66278B6F80C
annotation: SIP74F7EB8D61FA51AE
annotation: PRO_0000006534
annotation: SIP9A46AAA3F0372FC4
annotation: SIPE9862AA018BF5780
annotation: SIPF9EBED60F87938CB
annotation: SIPCD8F0F023DB73E1F
annotation: SIP924E29C940A6DCD2
annotation: SIP31ACD5FEAB3B4E2A
annotation: SIPE3BD362ACA8FD43D
annotation: SIP5A773BD65B0DFD83
annotation: SIPFC9771955A76240A
annotation: SIP199AF2FE7C2CE540
annotation: SIP3F33649D746E90A5
annotation: SIPA11A0E8CB525B7F6
annotation: SIP46AEC7A71A31B7C9
annotation: SIP3D0267DD05C1B0B9
annotation: SIP69003904C95C91F2
annotation: SIPD674CB340E9BC75E
annotation: SIP880805B7154B4E39
annotation: SIPD9DAC5219A696014
annotation: SIPAF0D5F005800A95B
annotation: SIP15CE79CBF8443C86
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/903
classified with: http://purl.uniprot.org/keywords/249
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/574
classified with: http://purl.uniprot.org/keywords/732
classified with: GO_0042597
classified with: GO_0009055
classified with: GO_0020037
classified with: GO_0005506
sequence: P74917-1

SIP4DFECD6624AD3A70
type: Submission Citation
author: Appia C.
author: Bengrine A.
author: Chippaux M.
author: Cavazza C.
author: Bruschi M.
author: Bonnefoy V.
date: 2001-08
submitted to: EMBL/GenBank/DDBJ

P74917-citation-SIP4DFECD6624AD3A70
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe
type: Strain

P74917-citation-8973648
type: Citation Statement
scope: PROTEIN SEQUENCE OF 48-95
scope: MASS SPECTROMETRY
scope: CHARACTERIZATION

1H1O
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.13
chain sequence mapping: PDB 1H1O tt48tt230

PDB 1H1O tt48tt230
chain: A/B=48-230

http://purl.uniprot.org/gene3d/1.10.760.10
type: Resource
database: Gene3D
comment: Cytochrome c-like domain
signature sequence match: Gene3D 1.10.760.10 match 1
signature sequence match: Gene3D 1.10.760.10 match 2

IPR009056
type: Resource
database: InterPro
comment: Cyt_c-like_dom

IPR036909
type: Resource
database: InterPro
comment: Cyt_c-like_dom_sf

IPR024167
type: Resource
database: InterPro
comment: Cytochrome_c4-like

PTHR33751
type: Resource
database: PANTHER
comment: CBB3-TYPE CYTOCHROME C OXIDASE SUBUNIT FIXP
signature sequence match: PANTHER PTHR33751 match 1

PTHR33751:SF9
type: Resource
database: PANTHER
comment: CYTOCHROME C4
signature sequence match: PANTHER PTHR33751:SF9 match 1

PF00034
type: Resource
database: Pfam
comment: Cytochrom_C
signature sequence match: Pfam PF00034 match 1
signature sequence match: Pfam PF00034 match 2

PIRSF000005
type: Resource
database: PIRSF
comment: Cytochrome_c4
signature sequence match: PIRSF PIRSF000005 match 1

SSF46626
type: Resource
database: SUPFAM
comment: Cytochrome c
signature sequence match: SUPFAM SSF46626 match 1
signature sequence match: SUPFAM SSF46626 match 2

PS51007
type: Resource
database: PROSITE
comment: CYTC
signature sequence match: PROSITE PS51007 match 1
signature sequence match: PROSITE PS51007 match 2

SIP097C334A225050D5
type: External Sequence
comment: AA sequence
citation: http://purl.uniprot.org/citations/8973648

SIP46E234A20120E7EA
type: Structured Name
full name: Cytochrome c-552

SIPC7C0ACF5683AB041
type: Structured Name
full name: Cytochrome c552

cyc1
type: Gene

SIP2FC41E6E4F984B4D
type: Function Annotation
comment: Diheme, high potential cytochrome c.

SIPF6A34B257051A47A
type: Redox Potential Annotation
comment: E(0) are +385 +/- 20 mV and +480 +/- 20 mV.

SIP161A4F6CD4552737
type: PTM Annotation
comment: Binds 2 heme c groups covalently per subunit.

SIP799FA66278B6F80C
type: Mass Spectrometry Annotation
measured value: 21193
method: ESI

22578695574206254tt1
type: Position
type: ExactPosition
position: 1
reference: P74917-1

22578695574206254tt47
type: Position
type: ExactPosition
position: 47
reference: P74917-1

PRO_0000006534
type: Chain Annotation
comment: Cytochrome c-552
mass: 19914
range: 22578695574206254tt48tt230

22578695574206254tt48
type: Position
type: ExactPosition
position: 48
reference: P74917-1

22578695574206254tt230
type: Position
type: ExactPosition
position: 230
reference: P74917-1

SIP9A46AAA3F0372FC4
type: Binding Site Annotation
comment: covalent
ligand: 1
range: 22578695574206254tt63tt63

22578695574206254tt63
type: Position
type: ExactPosition
position: 63
reference: P74917-1

SIPE9862AA018BF5780
type: Binding Site Annotation
comment: covalent
ligand: 1
range: 22578695574206254tt66tt66

22578695574206254tt66
type: Position
type: ExactPosition
position: 66
reference: P74917-1

SIPF9EBED60F87938CB
type: Binding Site Annotation
comment: axial binding residue
ligand: 1
ligand part: SIP85C37483D3E0B42A
range: 22578695574206254tt67tt67

22578695574206254tt67
type: Position
type: ExactPosition
position: 67
reference: P74917-1

SIPCD8F0F023DB73E1F
type: Binding Site Annotation
comment: covalent
ligand: 2
range: 22578695574206254tt166tt166

22578695574206254tt166
type: Position
type: ExactPosition
position: 166
reference: P74917-1

SIP924E29C940A6DCD2
type: Binding Site Annotation
comment: covalent
ligand: 2
range: 22578695574206254tt169tt169

22578695574206254tt169
type: Position
type: ExactPosition
position: 169
reference: P74917-1

SIP31ACD5FEAB3B4E2A
type: Binding Site Annotation
comment: axial binding residue
ligand: 2
ligand part: SIP428C6123B1B272B9
range: 22578695574206254tt170tt170

22578695574206254tt170
type: Position
type: ExactPosition
position: 170
reference: P74917-1

SIPE3BD362ACA8FD43D
type: Sequence Conflict Annotation
conflicting sequence: SIP097C334A225050D5
substitution: YI
range: 22578695574206254tt89tt89

22578695574206254tt89
type: Position
type: ExactPosition
position: 89
reference: P74917-1

22578695574206254tt60
type: Position
type: ExactPosition
position: 60
reference: P74917-1

22578695574206254tt62
type: Position
type: ExactPosition
position: 62
reference: P74917-1

22578695574206254tt64
type: Position
type: ExactPosition
position: 64
reference: P74917-1

22578695574206254tt87
type: Position
type: ExactPosition
position: 87
reference: P74917-1

22578695574206254tt98
type: Position
type: ExactPosition
position: 98
reference: P74917-1

22578695574206254tt105
type: Position
type: ExactPosition
position: 105
reference: P74917-1

22578695574206254tt110
type: Position
type: ExactPosition
position: 110
reference: P74917-1

22578695574206254tt112
type: Position
type: ExactPosition
position: 112
reference: P74917-1

22578695574206254tt116
type: Position
type: ExactPosition
position: 116
reference: P74917-1

22578695574206254tt120
type: Position
type: ExactPosition
position: 120
reference: P74917-1

22578695574206254tt132
type: Position
type: ExactPosition
position: 132
reference: P74917-1

22578695574206254tt147
type: Position
type: ExactPosition
position: 147
reference: P74917-1

22578695574206254tt156
type: Position
type: ExactPosition
position: 156
reference: P74917-1

22578695574206254tt159
type: Position
type: ExactPosition
position: 159
reference: P74917-1

22578695574206254tt161
type: Position
type: ExactPosition
position: 161
reference: P74917-1

22578695574206254tt167
type: Position
type: ExactPosition
position: 167
reference: P74917-1

22578695574206254tt188
type: Position
type: ExactPosition
position: 188
reference: P74917-1

22578695574206254tt200
type: Position
type: ExactPosition
position: 200
reference: P74917-1

22578695574206254tt201
type: Position
type: ExactPosition
position: 201
reference: P74917-1

22578695574206254tt203
type: Position
type: ExactPosition
position: 203
reference: P74917-1

22578695574206254tt206
type: Position
type: ExactPosition
position: 206
reference: P74917-1

22578695574206254tt212
type: Position
type: ExactPosition
position: 212
reference: P74917-1

22578695574206254tt217
type: Position
type: ExactPosition
position: 217
reference: P74917-1

22578695574206254tt229
type: Position
type: ExactPosition
position: 229
reference: P74917-1

1
subclass of: CHEBI_61717

2
subclass of: CHEBI_61717

P74917-1
type: Simple Sequence
modified: 1998-07-15
version: 2
precursor: true
mass: 25298
value: MTTYLSQDRLRNKENDTMTYQHSKMYQSRTFLLFSALLLVAGQASAAVGSADAPAPYRVSSDCMVCHGMTGRDTLYPIVPRLAGQHKSYMEAQLKAYKDHSRADQNGEIYMWPVAQALDSAKITALADYFNAQKPPMQSSGIKHAGAKEGKAIFNQGVTNEQIPACMECHGSDGQGAGPFPRLAGQRYGYIIQQLTYFHNGTRVNTLMNQIAKNITVAQMKDVAAYLSSL

http://purl.uniprot.org/uniprot/P74917#attribution-77CA0AB3DE3B0FAB3D5F74F61D9051E0
manual: true
evidence: ECO_0000255
source: PRU00433

http://purl.uniprot.org/uniprot/P74917#attribution-9592748748974EBBF52CEA4B32263E20
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/8973648

http://purl.uniprot.org/uniprot/P74917#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B7JAM6
type: Protein
reviewed: true
created: 2009-11-03
modified: 2023-05-03
version: 73
mnemonic: CYSI_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP112BE6771109E8CF
enzyme: http://purl.uniprot.org/enzyme/1.8.1.2
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP9D4327D02AF541C3
annotation: SIPAC742ADBC0DABD45
annotation: SIPE3F48E88610AEBCD
annotation: SIP15361D436EFEF6F0
annotation: SIPA9C5833366CBF9D6
annotation: SIP66A243A1FBCEE74B
annotation: SIP0F748FE52E820D31
annotation: PRO_0000388470
annotation: SIP703A7D0AC7A9189D
annotation: SIPCDA0EEE1D423753A
annotation: SIPB6851E8B9CAAB641
annotation: SIP8F4BB0658BCCCB6C
annotation: SIP46FE35F0B14FB0E4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/198
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0009337
classified with: GO_0051539
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0050661
classified with: GO_0004783
classified with: GO_0019344
classified with: GO_0070814
classified with: GO_0000103
sequence: B7JAM6-1
proteome: Chromosome

B7JAM6-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0155
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.30.413.10
type: Resource
database: Gene3D
comment: Sulfite Reductase Hemoprotein, domain 1
signature sequence match: Gene3D 3.30.413.10 match 1
signature sequence match: Gene3D 3.30.413.10 match 2

MF_01540
type: Resource
database: HAMAP
comment: CysI
signature sequence match: HAMAP MF 01540 match 1

IPR011786
type: Resource
database: InterPro
comment: CysI

IPR005117
type: Resource
database: InterPro
comment: NiRdtase/SiRdtase_haem-b_fer

IPR036136
type: Resource
database: InterPro
comment: Nit/Sulf_reduc_fer-like_dom_sf

IPR006067
type: Resource
database: InterPro
comment: NO2/SO3_Rdtase_4Fe4S_dom

IPR045169
type: Resource
database: InterPro
comment: NO2/SO3_Rdtase_4Fe4S_prot

IPR045854
type: Resource
database: InterPro
comment: NO2/SO3_Rdtase_4Fe4S_sf

IPR006066
type: Resource
database: InterPro
comment: NO2/SO3_Rdtase_FeS/sirohaem_BS

PTHR11493:SF47
type: Resource
database: PANTHER
comment: SULFITE REDUCTASE [NADPH] SUBUNIT BETA
signature sequence match: PANTHER PTHR11493:SF47 match 1

PTHR11493
type: Resource
database: PANTHER
comment: SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED
signature sequence match: PANTHER PTHR11493 match 1

PF01077
type: Resource
database: Pfam
comment: NIR_SIR
signature sequence match: Pfam PF01077 match 1

PF03460
type: Resource
database: Pfam
comment: NIR_SIR_ferr
signature sequence match: Pfam PF03460 match 1
signature sequence match: Pfam PF03460 match 2

PR00397
type: Resource
database: PRINTS
comment: SIROHAEM

SSF56014
type: Resource
database: SUPFAM
comment: Nitrite and sulphite reductase 4Fe-4S domain-like
signature sequence match: SUPFAM SSF56014 match 1
signature sequence match: SUPFAM SSF56014 match 2

SSF55124
type: Resource
database: SUPFAM
comment: Nitrite/Sulfite reductase N-terminal domain-like
signature sequence match: SUPFAM SSF55124 match 1
signature sequence match: SUPFAM SSF55124 match 2

PS00365
type: Resource
database: PROSITE
comment: NIR_SIR
signature sequence match: PROSITE PS00365 match 1

SIP112BE6771109E8CF
type: Structured Name
full name: Sulfite reductase [NADPH] hemoprotein beta-component
short name: SiR-HP
short name: SiRHP
ec name: 1.8.1.2

cysI
type: Gene
locus name: AFE_3122

SIP9D4327D02AF541C3
type: Function Annotation
comment: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

SIPE3F48E88610AEBCD
type: Cofactor Annotation
comment: Binds 1 siroheme per subunit.
cofactor: CHEBI_60052

SIP15361D436EFEF6F0
type: Cofactor Annotation
comment: Binds 1 [4Fe-4S] cluster per subunit.
cofactor: CHEBI_49883

SIP66A243A1FBCEE74B
type: Subunit Annotation
comment: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.

SIP0F748FE52E820D31
type: Similarity Annotation
comment: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

PRO_0000388470
type: Chain Annotation
comment: Sulfite reductase [NADPH] hemoprotein beta-component
mass: 61946
range: 18638140525590062tt1tt563

18638140525590062tt1
type: Position
type: ExactPosition
position: 1
reference: B7JAM6-1

18638140525590062tt563
type: Position
type: ExactPosition
position: 563
reference: B7JAM6-1

18638140525590062tt427
type: Position
type: ExactPosition
position: 427
reference: B7JAM6-1

18638140525590062tt433
type: Position
type: ExactPosition
position: 433
reference: B7JAM6-1

18638140525590062tt472
type: Position
type: ExactPosition
position: 472
reference: B7JAM6-1

18638140525590062tt476
type: Position
type: ExactPosition
position: 476
reference: B7JAM6-1

SIP46FE35F0B14FB0E4
type: Binding Site Annotation
comment: axial binding residue
ligand: SIP1C8547FA5315714B
ligand part: SIP5078E8E585470BA2
range: 18638140525590062tt476tt476

B7JAM6-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 61946
value: MSINDKALSDVERIKAESQGLRGTLRESLHNPVTGALAEDDVQVIKFHGIYQQDYRDLRAERHQQKLEPLYQFMARLRLPGGVLSGAQWLALGDIARTYGNASLRITSRQSIQFHGLLKPHLRPVLQALDRALLDTVSACGDVNRNVIASSAPQISAFHAEAYGWAQKIAEHLLPQSHAYHEIWLGGQQITAPEEDLLYGSTYLPRKFKIAIAVPPHNDVDVLTQDLGFIAIHEEGRLAGFNVCVGGGLGRSHNKPDTYSRLADVCGFCAPGQVLAIAEAVLITQRDHGDRSNRSHARLKYTVDRMGLDRFMEEVQQRTGFSLAPPRPFHFETSGDRFGWLENDDGTACLTLFIPGGRVADGDIPLLSGLDALARLHHGEIRLTCNQNLLIAGISPAERPVVETVLAEYGLNRLLNLAPVRAHAMACVALPTCPLAMAEAERYLPVFLDRIEALLAEVGLEGEALTVRMTGCPNGCARPYLAEIGLVGKAPGLYDLYLGGDRTGMRLNALYREALDEEALLDALRPLLKRFAGQRWAGETFGDFVRRQDLLPPDPGLPHTGRR

http://purl.uniprot.org/uniprot/B7JAM6#attribution-747B76829C828BA633C0E21975D6BD6A
manual: true
evidence: ECO_0000255
source: MF_01540

B5EQW2
type: Protein
reviewed: true
created: 2009-11-03
modified: 2023-05-03
version: 75
mnemonic: CYSI_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP112BE6771109E8CF
enzyme: http://purl.uniprot.org/enzyme/1.8.1.2
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP5F5E778EA4E39A99
annotation: SIPEE51D013921FC515
annotation: SIP2A2100BBB9ED6571
annotation: SIP048688B298B9546F
annotation: SIP6F02943EBB879224
annotation: SIPBE54E5DAED9E8FDC
annotation: SIP4A0086F485D30FC5
annotation: PRO_0000388471
annotation: SIPCA99FBCA36203607
annotation: SIP5823E2BC8392E356
annotation: SIP453B7AA189AD98B9
annotation: SIPFA88B006911103E0
annotation: SIP278D3FB346140C02
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/198
classified with: http://purl.uniprot.org/keywords/349
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: GO_0009337
classified with: GO_0051539
classified with: GO_0020037
classified with: GO_0046872
classified with: GO_0050661
classified with: GO_0004783
classified with: GO_0019344
classified with: GO_0070814
classified with: GO_0000103
sequence: B5EQW2-1

B5EQW2-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP112BE6771109E8CF
type: Structured Name
full name: Sulfite reductase [NADPH] hemoprotein beta-component
short name: SiR-HP
short name: SiRHP
ec name: 1.8.1.2

cysI
type: Gene
locus name: Lferr_2721

SIP5F5E778EA4E39A99
type: Function Annotation
comment: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

SIP2A2100BBB9ED6571
type: Cofactor Annotation
comment: Binds 1 siroheme per subunit.
cofactor: CHEBI_60052

SIP048688B298B9546F
type: Cofactor Annotation
comment: Binds 1 [4Fe-4S] cluster per subunit.
cofactor: CHEBI_49883

SIPBE54E5DAED9E8FDC
type: Subunit Annotation
comment: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.

SIP4A0086F485D30FC5
type: Similarity Annotation
comment: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

PRO_0000388471
type: Chain Annotation
comment: Sulfite reductase [NADPH] hemoprotein beta-component
mass: 61946
range: 18635920296587822tt1tt563

18635920296587822tt1
type: Position
type: ExactPosition
position: 1
reference: B5EQW2-1

18635920296587822tt563
type: Position
type: ExactPosition
position: 563
reference: B5EQW2-1

18635920296587822tt427
type: Position
type: ExactPosition
position: 427
reference: B5EQW2-1

18635920296587822tt433
type: Position
type: ExactPosition
position: 433
reference: B5EQW2-1

18635920296587822tt472
type: Position
type: ExactPosition
position: 472
reference: B5EQW2-1

18635920296587822tt476
type: Position
type: ExactPosition
position: 476
reference: B5EQW2-1

SIP278D3FB346140C02
type: Binding Site Annotation
comment: axial binding residue
ligand: SIP1C8547FA5315714B
ligand part: SIP5078E8E585470BA2
range: 18635920296587822tt476tt476

B5EQW2-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 61946
value: MSINDKALSDVERIKAESQGLRGTLRESLHNPVTGALAEDDVQVIKFHGIYQQDYRDLRAERHQQKLEPLYQFMARLRLPGGVLSGAQWLALGDIARTYGNASLRITSRQSIQFHGLLKPHLRPVLQALDRALLDTVSACGDVNRNVIASSAPQISAFHAEAYGWAQKIAEHLLPQSHAYHEIWLGGQQITAPEEDLLYGSTYLPRKFKIAIAVPPHNDVDVLTQDLGFIAIHEEGRLAGFNVCVGGGLGRSHNKPDTYSRLADVCGFCAPGQVLAIAEAVLITQRDHGDRSNRSHARLKYTVDRMGLDRFMEEVQQRTGFSLAPPRPFHFETSGDRFGWLENDDGTACLTLFIPGGRVADGDIPLLSGLDALARLHHGEIRLTCNQNLLIAGISPAERPVVETVLAEYGLNRLLNLAPVRAHAMACVALPTCPLAMAEAERYLPVFLDRIEALLAEVGLEGEALTVRMTGCPNGCARPYLAEIGLVGKAPGLYDLYLGGDRTGMRLNALYREALDEEALLDALRPLLKRFAGQRWAGETFGDFVRRQDLLPPDPGLPHTGRR

http://purl.uniprot.org/uniprot/B5EQW2#attribution-747B76829C828BA633C0E21975D6BD6A
manual: true
evidence: ECO_0000255
source: MF_01540

B7JB00
type: Protein
reviewed: true
created: 2009-11-03
modified: 2023-05-03
version: 59
mnemonic: DABA_ACIF2
old mnemonic: Y1661_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP625FCC8B7C4B4B8B
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPA2823046BC0BB736
annotation: SIPEA78B3CEC0EF2C37
annotation: SIP2D38AFE0A5E1A03E
annotation: SIP63340271E2FCBF93
annotation: SIPF2F1EBFF69F8230B
annotation: PRO_0000387227
annotation: SIPCF48D947C1CE00A7
annotation: SIP555772D627FC84D7
annotation: SIPBDB4AF2C3C2917DC
annotation: SIP9A206762361F9807
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/813
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005886
classified with: GO_0008270
sequence: B7JB00-1
proteome: Chromosome

B7JB00-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG3002
type: Resource
database: eggNOG
comment: Bacteria

MF_01871
type: Resource
database: HAMAP
comment: DabA
signature sequence match: HAMAP MF 01871 match 1

IPR018752
type: Resource
database: InterPro
comment: DabA

PTHR38344
type: Resource
database: PANTHER
comment: UPF0753 PROTEIN AQ_863
signature sequence match: PANTHER PTHR38344 match 1

PTHR38344:SF1
type: Resource
database: PANTHER
comment: UPF0753 PROTEIN YBCC
signature sequence match: PANTHER PTHR38344:SF1 match 1

PF10070
type: Resource
database: Pfam
comment: DabA
signature sequence match: Pfam PF10070 match 1

SIP625FCC8B7C4B4B8B
type: Structured Name
full name: Probable inorganic carbon transporter subunit DabA

dabA
type: Gene
locus name: AFE_1661

SIPA2823046BC0BB736
type: Function Annotation
comment: Part of an energy-coupled inorganic carbon pump.

SIP2D38AFE0A5E1A03E
type: Subunit Annotation
comment: Forms a complex with DabB.

SIPF2F1EBFF69F8230B
type: Similarity Annotation
comment: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.

PRO_0000387227
type: Chain Annotation
comment: Probable inorganic carbon transporter subunit DabA
mass: 92277
range: 18638140540465198tt1tt825

18638140540465198tt1
type: Position
type: ExactPosition
position: 1
reference: B7JB00-1

18638140540465198tt825
type: Position
type: ExactPosition
position: 825
reference: B7JB00-1

18638140540465198tt334
type: Position
type: ExactPosition
position: 334
reference: B7JB00-1

18638140540465198tt336
type: Position
type: ExactPosition
position: 336
reference: B7JB00-1

18638140540465198tt521
type: Position
type: ExactPosition
position: 521
reference: B7JB00-1

18638140540465198tt536
type: Position
type: ExactPosition
position: 536
reference: B7JB00-1

B7JB00-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 92277
value: MPTPATIKSYQDIKANIEGACQRIAPLWPLKHFVAVNPYVGLRDQPFWRADQTLRKITGKGLTMPRPYYEEQIANGRIIQEDLDEALKQMHSNWSVTQLKQVMKQRSASRNVPFPVFADAMFADDRRDWPGFVVERISQYCAAYFDEGQATWSMPWRDDPMYQAWLKFMHFDKSPRMVGLRGIGEAAAALPAAAETAIALALKELSVPFDLIDDYLFAALLSIGGWAGWARYLRWQAELKGETDQSLRDLLAIRVCWDAILHKTCADIAVRKQWHLMLHTQQNRAIEKPSEHVDAILQTALEIGYQRSLIKSLKEASRPSNTVIERPVAQAAFCIDVRSEIIRRALETVAPGIQTLGFAGFFGVLMEYVPFGSNAPKGHLPVIFNPPYRVCEDLSHASEDETQRHAAKRQLRLRVATAWKSFKTSAVSTFTFVEATGLLYAPKLFGDSMGWTRTVPHPDERGLDSGTKQRLRPRLIASGNGKSSAKSTGIPETERAGVGEFILKNMGLTQTFARLILLAGHGSTTVNNPQGTGLDCGACAGQTGEASARIAVTLLNDPATRRGLEEKGLKIPKDTYFIAGLHDTTTDEVTIFDTEDLPTTHAKDLAQLRQWLADAGELTRLERATLLGTASQAPEVVTRDMRRRTRDWAEVRPEWALAGNAAFIAAPRQRTRGVDLEGRAFLHDYDWHKDAGFSTLELIMTAPMVVANWINMQYYGSMVDNLRFGSGNKVLHNVVGGSIGVLEGNGGDLRVGFALQSLHDGKRWIHEPVRLNVVIEAPQAEMESIISRHILVRELVDNGWLYLFQIDDDGSVYRRVCDKQWPRMT

http://purl.uniprot.org/uniprot/B7JB00#attribution-ECA8209EFF680E087F8BD9CB4CAE95BB
manual: true
evidence: ECO_0000255
source: MF_01871

B5ERS0
type: Protein
reviewed: true
created: 2009-11-03
modified: 2023-05-03
version: 60
mnemonic: DABA_ACIF5
old mnemonic: Y1358_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP625FCC8B7C4B4B8B
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP839FC27903CB4B4D
annotation: SIPF97DB0A9972530F0
annotation: SIP7BFEB7F3C14D0CFA
annotation: SIPFE7F8F706DF26A2B
annotation: SIPFC9065F883750531
annotation: PRO_0000387228
annotation: SIPF3DF85CAAFE4CD43
annotation: SIPBA07BA731F3CAAE6
annotation: SIP78DFE23789A6967F
annotation: SIP30F4446179036A3B
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/813
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005886
classified with: GO_0008270
sequence: B5ERS0-1

B5ERS0-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP625FCC8B7C4B4B8B
type: Structured Name
full name: Probable inorganic carbon transporter subunit DabA

dabA
type: Gene
locus name: Lferr_1358

SIP839FC27903CB4B4D
type: Function Annotation
comment: Part of an energy-coupled inorganic carbon pump.

SIP7BFEB7F3C14D0CFA
type: Subunit Annotation
comment: Forms a complex with DabB.

SIPFC9065F883750531
type: Similarity Annotation
comment: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.

PRO_0000387228
type: Chain Annotation
comment: Probable inorganic carbon transporter subunit DabA
mass: 92340
range: 18635920313102382tt1tt825

18635920313102382tt1
type: Position
type: ExactPosition
position: 1
reference: B5ERS0-1

18635920313102382tt825
type: Position
type: ExactPosition
position: 825
reference: B5ERS0-1

18635920313102382tt334
type: Position
type: ExactPosition
position: 334
reference: B5ERS0-1

18635920313102382tt336
type: Position
type: ExactPosition
position: 336
reference: B5ERS0-1

18635920313102382tt521
type: Position
type: ExactPosition
position: 521
reference: B5ERS0-1

18635920313102382tt536
type: Position
type: ExactPosition
position: 536
reference: B5ERS0-1

B5ERS0-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 92340
value: MQTPATIKSYQDIKANIEKACQRIAPLWPLKHFVAVNPYVGLRDQPFWRADQTLRKITGKGLTMPRPYYEEQIANGRITQEDLDEALKEMHSNWSVTQLKQAMKQRSASRNVPFPVFADAMFADDRRDWPGFVVERISQYCAAYFDEGQATWSMPWRDDPMYQAWLKFMHFDKSPRMVGLRGIGEAAAALPAAAETAIALALKELSVPFDLIDDYLFAALLSIGGWAGWARYLRWQAELKGETDQSLRDLLAIRVCWDAILHKTCADIAVRKQWHLMLHTQQNRAIEKPSEHVDAILQTALEIGYQRSLIKSLKEASRPSNTVIERPVAQAAFCIDVRSEIIRRALETVAPGIQTLGFAGFFGVLMEYVPFGSNAPKGHLPVIFNPPYRVCEDLSHASEDETQRHAAKRQLRLRVATAWKSFKTSAVSTFTFVEATGLLYAPKLFGDSMGWTRTVPHPDERGLDSGTKQRLRPRLIASGNGKSSAKSTGIPETERAGVGEFILKNMGLTQTFARLILLAGHGSTTVNNPQGTGLDCGACAGQTGEASARIAVTLLNDPATRRGLEEKGLKIPKDTYFIAGLHDTTTDEVTIFDTEDLPTTHAKDLAQLRQWLADAGELTRLERATLLGTASQAPEVVTRDMRRRTRDWAEVRPEWALAGNAAFIAAPRQRTRGVDLEGRAFLHDYDWHKDAGFSTLELIMTAPMVVANWINMQYYGSMVDNLRFGSGNKVLHNVVGGSIGVLEGNGGDLRVGFALQSLHDGKRWIHEPVRLNVVIEAPQAEMESIISRHILVRELVDNGWLYLFQIDDDGSVYRRVCDKQWPRMT

http://purl.uniprot.org/uniprot/B5ERS0#attribution-ECA8209EFF680E087F8BD9CB4CAE95BB
manual: true
evidence: ECO_0000255
source: MF_01871

B7J6C4
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 74
mnemonic: DAPA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP3DCCD2FAF2A8502D
enzyme: http://purl.uniprot.org/enzyme/4.3.3.7
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP5BA96AFCE87621FC
annotation: SIP0BFEECF169E7543E
annotation: SIP88DB8E649823356E
annotation: SIP3EA90304426B648F
annotation: SIPA79C550499CCC977
annotation: SIPDEADEC093ED045FD
annotation: SIPFCF9B34B2DF7447E
annotation: PRO_1000124012
annotation: SIP80F5FDD03B2A2D40
annotation: SIP73E03963DDA48C8B
annotation: SIP5ED1728FAB66D33C
annotation: SIP1C75AE20063C2017
annotation: SIP877F5968C53A1F38
annotation: SIP960AAF3F85A67F98
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0005737
classified with: GO_0008840
classified with: GO_0019877
classified with: GO_0009089
sequence: B7J6C4-1
proteome: Chromosome

B7J6C4-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0329
type: Resource
database: eggNOG
comment: Bacteria

cd00950
type: Resource
database: CDD
comment: DHDPS
signature sequence match: CDD cd00950 match 1

MF_00418
type: Resource
database: HAMAP
comment: DapA
signature sequence match: HAMAP MF 00418 match 1

IPR005263
type: Resource
database: InterPro
comment: DapA

IPR002220
type: Resource
database: InterPro
comment: DapA-like

IPR020625
type: Resource
database: InterPro
comment: Schiff_base-form_aldolases_AS

IPR020624
type: Resource
database: InterPro
comment: Schiff_base-form_aldolases_CS

PTHR12128:SF66
type: Resource
database: PANTHER
comment: 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128:SF66 match 1

PTHR12128
type: Resource
database: PANTHER
comment: DIHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128 match 1

PF00701
type: Resource
database: Pfam
comment: DHDPS
signature sequence match: Pfam PF00701 match 1

PIRSF001365
type: Resource
database: PIRSF
comment: DHDPS
signature sequence match: PIRSF PIRSF001365 match 1

PR00146
type: Resource
database: PRINTS
comment: DHPICSNTHASE

SM01130
type: Resource
database: SMART
comment: DHDPS
signature sequence match: SMART SM01130 match 1

SSF51569
type: Resource
database: SUPFAM
comment: Aldolase
signature sequence match: SUPFAM SSF51569 match 1

TIGR00674
type: Resource
database: TIGRFAMs
comment: dapA
signature sequence match: TIGRFAMs TIGR00674 match 1

PS00665
type: Resource
database: PROSITE
comment: DHDPS_1
signature sequence match: PROSITE PS00665 match 1

PS00666
type: Resource
database: PROSITE
comment: DHDPS_2
signature sequence match: PROSITE PS00666 match 1

SIP3DCCD2FAF2A8502D
type: Structured Name
full name: 4-hydroxy-tetrahydrodipicolinate synthase
short name: HTPA synthase
ec name: 4.3.3.7

dapA
type: Gene
locus name: AFE_2358

SIP5BA96AFCE87621FC
type: Function Annotation
comment: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

SIP3EA90304426B648F
type: Subunit Annotation
comment: Homotetramer; dimer of dimers.

SIPDEADEC093ED045FD
type: Similarity Annotation
comment: Belongs to the DapA family.

SIPFCF9B34B2DF7447E
type: Caution Annotation
comment: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

PRO_1000124012
type: Chain Annotation
comment: 4-hydroxy-tetrahydrodipicolinate synthase
mass: 31199
range: 18638140340384814tt1tt291

18638140340384814tt1
type: Position
type: ExactPosition
position: 1
reference: B7J6C4-1

18638140340384814tt291
type: Position
type: ExactPosition
position: 291
reference: B7J6C4-1

SIP80F5FDD03B2A2D40
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18638140340384814tt133tt133

18638140340384814tt133
type: Position
type: ExactPosition
position: 133
reference: B7J6C4-1

SIP73E03963DDA48C8B
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 18638140340384814tt161tt161

18638140340384814tt161
type: Position
type: ExactPosition
position: 161
reference: B7J6C4-1

18638140340384814tt45
type: Position
type: ExactPosition
position: 45
reference: B7J6C4-1

18638140340384814tt203
type: Position
type: ExactPosition
position: 203
reference: B7J6C4-1

SIP877F5968C53A1F38
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18638140340384814tt44tt44

18638140340384814tt44
type: Position
type: ExactPosition
position: 44
reference: B7J6C4-1

SIP960AAF3F85A67F98
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18638140340384814tt107tt107

18638140340384814tt107
type: Position
type: ExactPosition
position: 107
reference: B7J6C4-1

B7J6C4-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 31199
value: MFHGSMVALVTPMQVDGAIDDVALRELVEWHIAEGTHALVAVGTTGESATLEMREHVAVIQTVVEQARGRVPVIAGTGANATHEAIELTRAAMEVKADAALLVSPYYNKPTQEGLFQHYSAIAEHCHFPIILYNVPGRTAGDILPETVARLAPRADIIGIKEASGKVERVAEILALCGDQVQVYSGDDGAALAAMALGARGVISVTANAAPRLMARMCDLALAGDFVGARAVNAQLTGLHRDLFLESNPIPVKWALHEMGRMESVLRLPLTTLSSVHHERLRESLRRAQCI

http://purl.uniprot.org/uniprot/B7J6C4#attribution-BD5BACAA957515974E6FCCE76684BF01
manual: true
evidence: ECO_0000255
source: MF_00418

http://purl.uniprot.org/uniprot/B7J6C4#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B5ELM5
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 75
mnemonic: DAPA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP3DCCD2FAF2A8502D
enzyme: http://purl.uniprot.org/enzyme/4.3.3.7
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP071CFA12ABE68B83
annotation: SIP50AD48C2A3F37160
annotation: SIP6B7835ABAD759082
annotation: SIP1250448EC1CC0D42
annotation: SIPF584593038E5B5F1
annotation: SIP2660E8A5333124FA
annotation: SIPE443CFA62D16126F
annotation: PRO_1000124013
annotation: SIPEAE305E8B2215852
annotation: SIPFAF2BEAA28880B06
annotation: SIP4CBD8637C1AA2512
annotation: SIP94591560B6746A99
annotation: SIPE7858F654040C694
annotation: SIPD15083DDF95372EE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0005737
classified with: GO_0008840
classified with: GO_0019877
classified with: GO_0009089
sequence: B5ELM5-1

B5ELM5-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP3DCCD2FAF2A8502D
type: Structured Name
full name: 4-hydroxy-tetrahydrodipicolinate synthase
short name: HTPA synthase
ec name: 4.3.3.7

dapA
type: Gene
locus name: Lferr_1992

SIP071CFA12ABE68B83
type: Function Annotation
comment: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

SIP1250448EC1CC0D42
type: Subunit Annotation
comment: Homotetramer; dimer of dimers.

SIP2660E8A5333124FA
type: Similarity Annotation
comment: Belongs to the DapA family.

SIPE443CFA62D16126F
type: Caution Annotation
comment: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

PRO_1000124013
type: Chain Annotation
comment: 4-hydroxy-tetrahydrodipicolinate synthase
mass: 31199
range: 18635920212047150tt1tt291

18635920212047150tt1
type: Position
type: ExactPosition
position: 1
reference: B5ELM5-1

18635920212047150tt291
type: Position
type: ExactPosition
position: 291
reference: B5ELM5-1

SIPEAE305E8B2215852
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18635920212047150tt133tt133

18635920212047150tt133
type: Position
type: ExactPosition
position: 133
reference: B5ELM5-1

SIPFAF2BEAA28880B06
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 18635920212047150tt161tt161

18635920212047150tt161
type: Position
type: ExactPosition
position: 161
reference: B5ELM5-1

18635920212047150tt45
type: Position
type: ExactPosition
position: 45
reference: B5ELM5-1

18635920212047150tt203
type: Position
type: ExactPosition
position: 203
reference: B5ELM5-1

SIPE7858F654040C694
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18635920212047150tt44tt44

18635920212047150tt44
type: Position
type: ExactPosition
position: 44
reference: B5ELM5-1

SIPD15083DDF95372EE
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 18635920212047150tt107tt107

18635920212047150tt107
type: Position
type: ExactPosition
position: 107
reference: B5ELM5-1

B5ELM5-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 31199
value: MFHGSMVALVTPMQVDGAIDDVALRELVEWHIAEGTHALVAVGTTGESATLEMREHVAVIQTVVEQARGRVPVIAGTGANATHEAIELTRAAMEVKADAALLVSPYYNKPTQEGLFQHYSAIAEHCHFPIILYNVPGRTAGDILPETVARLAPRADIIGIKEASGKVERVAEILALCGDQVQVYSGDDGAALAAMALGARGVISVTANAAPRLMARMCDLALAGDFVGARAVNAQLTGLHRDLFLESNPIPVKWALHEMGRMESVLRLPLTTLSSVHHERLRESLRRAQCI

http://purl.uniprot.org/uniprot/B5ELM5#attribution-BD5BACAA957515974E6FCCE76684BF01
manual: true
evidence: ECO_0000255
source: MF_00418

http://purl.uniprot.org/uniprot/B5ELM5#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

B7JBS5
type: Protein
reviewed: true
created: 2009-05-26
modified: 2023-05-03
version: 71
mnemonic: DAPE_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP940409A2ABB01B77
alternative name: SIPEDF5303665E61462
enzyme: http://purl.uniprot.org/enzyme/3.5.1.18
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPC10B067370872A5C
annotation: SIPBE01D95FB846C72C
annotation: SIP3F2BF4E76AE26468
annotation: SIPD85AD98A3A2ACC14
annotation: SIPED4DF29461790E6F
annotation: SIP19294F709C5A1584
annotation: PRO_0000375438
annotation: SIP31886D4EAEA042D6
annotation: SIPF986485A7D20EB09
annotation: SIPCDE172FBD6B5C41D
annotation: SIPCAEF4628A857DBA5
annotation: SIP739F39620E7EC6FA
annotation: SIP3B2FA4C8CA499338
annotation: SIP895D8FC4B102496E
annotation: SIP57DB96BD8033D8FE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0050897
classified with: GO_0009014
classified with: GO_0008270
classified with: GO_0019877
classified with: GO_0009089
sequence: B7JBS5-1
proteome: Chromosome

B7JBS5-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0624
type: Resource
database: eggNOG
comment: Bacteria

cd03891
type: Resource
database: CDD
comment: M20_DapE_proteobac
signature sequence match: CDD cd03891 match 1

MF_01690
type: Resource
database: HAMAP
comment: DapE
signature sequence match: HAMAP MF 01690 match 1

IPR001261
type: Resource
database: InterPro
comment: ArgE/DapE_CS

IPR036264
type: Resource
database: InterPro
comment: Bact_exopeptidase_dim_dom

IPR005941
type: Resource
database: InterPro
comment: DapE_proteobac

IPR002933
type: Resource
database: InterPro
comment: Peptidase_M20

IPR011650
type: Resource
database: InterPro
comment: Peptidase_M20_dimer

PTHR43808
type: Resource
database: PANTHER
comment: ACETYLORNITHINE DEACETYLASE
signature sequence match: PANTHER PTHR43808 match 1

PTHR43808:SF31
type: Resource
database: PANTHER
comment: DIPEPTIDASE YTJP-RELATED
signature sequence match: PANTHER PTHR43808:SF31 match 1

PF07687
type: Resource
database: Pfam
comment: M20_dimer
signature sequence match: Pfam PF07687 match 1

PF01546
type: Resource
database: Pfam
comment: Peptidase_M20
signature sequence match: Pfam PF01546 match 1

SSF55031
type: Resource
database: SUPFAM
comment: Bacterial exopeptidase dimerisation domain
signature sequence match: SUPFAM SSF55031 match 1

TIGR01246
type: Resource
database: TIGRFAMs
comment: dapE_proteo
signature sequence match: TIGRFAMs TIGR01246 match 1

PS00759
type: Resource
database: PROSITE
comment: ARGE_DAPE_CPG2_2
signature sequence match: PROSITE PS00759 match 1

SIP940409A2ABB01B77
type: Structured Name
full name: Succinyl-diaminopimelate desuccinylase
short name: SDAP desuccinylase
ec name: 3.5.1.18

SIPEDF5303665E61462
type: Structured Name
full name: N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase

dapE
type: Gene
locus name: AFE_1819

SIPC10B067370872A5C
type: Function Annotation
comment: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.

SIP3F2BF4E76AE26468
type: Cofactor Annotation
comment: Binds 2 Zn(2+) or Co(2+) ions per subunit.
cofactor: CHEBI_29105
cofactor: CHEBI_48828

SIPED4DF29461790E6F
type: Subunit Annotation
comment: Homodimer.

SIP19294F709C5A1584
type: Similarity Annotation
comment: Belongs to the peptidase M20A family. DapE subfamily.

PRO_0000375438
type: Chain Annotation
comment: Succinyl-diaminopimelate desuccinylase
mass: 41156
range: 18638140542760238tt1tt382

18638140542760238tt1
type: Position
type: ExactPosition
position: 1
reference: B7JBS5-1

18638140542760238tt382
type: Position
type: ExactPosition
position: 382
reference: B7JBS5-1

18638140542760238tt70
type: Position
type: ExactPosition
position: 70
reference: B7JBS5-1

SIPF986485A7D20EB09
type: Active Site Annotation
comment: Proton acceptor
range: 18638140542760238tt135tt135

18638140542760238tt135
type: Position
type: ExactPosition
position: 135
reference: B7JBS5-1

18638140542760238tt68
type: Position
type: ExactPosition
position: 68
reference: B7JBS5-1

18638140542760238tt101
type: Position
type: ExactPosition
position: 101
reference: B7JBS5-1

18638140542760238tt136
type: Position
type: ExactPosition
position: 136
reference: B7JBS5-1

18638140542760238tt164
type: Position
type: ExactPosition
position: 164
reference: B7JBS5-1

18638140542760238tt350
type: Position
type: ExactPosition
position: 350
reference: B7JBS5-1

1
subclass of: CHEBI_29105

2
subclass of: CHEBI_29105

B7JBS5-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 41156
value: MGKSAVLELAEDLISRPSVTPEDAGCQELMIARLKAVGFRVTRLPANGVENFWAERGGAGPRLCFAGHTDVVPSGPLAEWQNDPFQPIIRDGMLYGRGAADMKGSLAAMVVAAERFVALHPAHSGRLAFLITSDEEGIATHGTRHVVDWLREHGETIDWCVVGEPSSEKVLGDVIKNGRRGSLNGRLTVHGIQGHVAYPDKADNPIHRAFRPLADLVDQSWDAGNDFFPPTRLQFSNIHAGTGANNVIPGQLQADFNFRFSTESTPESLQAGVHKILDASAMRYTIDWQLSGPPFFTAPGPLVAATQKALQAVEQRVAQLSTGGGTSDGRFIAQLGGQVVELGPVNATIHKINECVAVADLEHLAQIYMEIMVHLLETANGR

http://purl.uniprot.org/uniprot/B7JBS5#attribution-6C748251BEDA78C1A6122C288516E40E
manual: true
evidence: ECO_0000255
source: MF_01690

B5ES53
type: Protein
reviewed: true
created: 2009-05-26
modified: 2023-05-03
version: 77
mnemonic: DAPE_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP940409A2ABB01B77
alternative name: SIPEDF5303665E61462
enzyme: http://purl.uniprot.org/enzyme/3.5.1.18
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPFB682448F464E6CD
annotation: SIP748D197574B58724
annotation: SIP4578E6B4C1829ED3
annotation: SIP37C970D85138D948
annotation: SIP01CAE4CAE2AD0388
annotation: SIPBE67773DD7530326
annotation: PRO_0000375439
annotation: SIPCB3B2DE5BEFAB765
annotation: SIP82A290A9879191E5
annotation: SIPC132E131BD97C72E
annotation: SIPCD86493B7B11019B
annotation: SIPFA74ED6ECAE5631A
annotation: SIP7F2E031C48E646BA
annotation: SIP3F78C57233DC08A6
annotation: SIP6C69EE7B612CE057
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/170
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0050897
classified with: GO_0009014
classified with: GO_0008270
classified with: GO_0019877
classified with: GO_0009089
sequence: B5ES53-1

B5ES53-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP940409A2ABB01B77
type: Structured Name
full name: Succinyl-diaminopimelate desuccinylase
short name: SDAP desuccinylase
ec name: 3.5.1.18

SIPEDF5303665E61462
type: Structured Name
full name: N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase

dapE
type: Gene
locus name: Lferr_1496

SIPFB682448F464E6CD
type: Function Annotation
comment: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.

SIP4578E6B4C1829ED3
type: Cofactor Annotation
comment: Binds 2 Zn(2+) or Co(2+) ions per subunit.
cofactor: CHEBI_29105
cofactor: CHEBI_48828

SIP01CAE4CAE2AD0388
type: Subunit Annotation
comment: Homodimer.

SIPBE67773DD7530326
type: Similarity Annotation
comment: Belongs to the peptidase M20A family. DapE subfamily.

PRO_0000375439
type: Chain Annotation
comment: Succinyl-diaminopimelate desuccinylase
mass: 41156
range: 18635920327914286tt1tt382

18635920327914286tt1
type: Position
type: ExactPosition
position: 1
reference: B5ES53-1

18635920327914286tt382
type: Position
type: ExactPosition
position: 382
reference: B5ES53-1

18635920327914286tt70
type: Position
type: ExactPosition
position: 70
reference: B5ES53-1

SIP82A290A9879191E5
type: Active Site Annotation
comment: Proton acceptor
range: 18635920327914286tt135tt135

18635920327914286tt135
type: Position
type: ExactPosition
position: 135
reference: B5ES53-1

18635920327914286tt68
type: Position
type: ExactPosition
position: 68
reference: B5ES53-1

18635920327914286tt101
type: Position
type: ExactPosition
position: 101
reference: B5ES53-1

18635920327914286tt136
type: Position
type: ExactPosition
position: 136
reference: B5ES53-1

18635920327914286tt164
type: Position
type: ExactPosition
position: 164
reference: B5ES53-1

18635920327914286tt350
type: Position
type: ExactPosition
position: 350
reference: B5ES53-1

1
subclass of: CHEBI_29105

2
subclass of: CHEBI_29105

B5ES53-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 41156
value: MGKSAVLELAEDLISRPSVTPEDAGCQELMIARLKAVGFRVTRLPANGVENFWAERGGAGPRLCFAGHTDVVPSGPLAEWQNDPFQPIIRDGMLYGRGAADMKGSLAAMVVAAERFVALHPAHSGRLAFLITSDEEGIATHGTRHVVDWLREHGETIDWCVVGEPSSEKVLGDVIKNGRRGSLNGRLTVHGIQGHVAYPDKADNPIHRAFRPLADLVDQSWDAGNDFFPPTRLQFSNIHAGTGANNVIPGQLQADFNFRFSTESTPESLQAGVHKILDASAMRYTIDWQLSGPPFFTAPGPLVAATQKALQAVEQRVAQLSTGGGTSDGRFIAQLGGQVVELGPVNATIHKINECVAVADLEHLAQIYMEIMVHLLETANGR

http://purl.uniprot.org/uniprot/B5ES53#attribution-6C748251BEDA78C1A6122C288516E40E
manual: true
evidence: ECO_0000255
source: MF_01690

B7J7X4
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 71
mnemonic: DCD_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP3334ADF56A9CDDC0
alternative name: SIP8B976E765BA78420
enzyme: http://purl.uniprot.org/enzyme/3.5.4.13
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP975899FC1B7FBF6B
annotation: SIP5AF62E63218F3067
annotation: SIP5A5415B66F790E33
annotation: SIP4A66EEED137D22E1
annotation: SIP8A8EB4D97C7AFBF1
annotation: PRO_1000189820
annotation: SIPDF3829456E084FC1
annotation: SIP34749EB36EBAF601
annotation: SIP0B923114648C6CFB
annotation: SIPEF75CA4A8955992C
annotation: SIP3B677AD4EBD176D0
annotation: SIP678CA7B15495F19D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/546
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0008829
classified with: GO_0000166
classified with: GO_0006226
classified with: GO_0006229
sequence: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA
proteome: Chromosome

B7J7X4-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0717
type: Resource
database: eggNOG
comment: Bacteria

cd07557
type: Resource
database: CDD
comment: trimeric_dUTPase
signature sequence match: CDD cd07557 match 1

MF_00146
type: Resource
database: HAMAP
comment: dCTP_deaminase
signature sequence match: HAMAP MF 00146 match 1

IPR011962
type: Resource
database: InterPro
comment: dCTP_deaminase

IPR029054
type: Resource
database: InterPro
comment: dUTPase-like

IPR036157
type: Resource
database: InterPro
comment: dUTPase-like_sf

IPR033704
type: Resource
database: InterPro
comment: dUTPase_trimeric

PTHR42680
type: Resource
database: PANTHER
comment: DCTP DEAMINASE
signature sequence match: PANTHER PTHR42680 match 1

PTHR42680:SF3
type: Resource
database: PANTHER
comment: DCTP DEAMINASE
signature sequence match: PANTHER PTHR42680:SF3 match 1

PF00692
type: Resource
database: Pfam
comment: dUTPase
signature sequence match: Pfam PF00692 match 1

SSF51283
type: Resource
database: SUPFAM
comment: dUTPase-like
signature sequence match: SUPFAM SSF51283 match 1

TIGR02274
type: Resource
database: TIGRFAMs
comment: dCTP_deam
signature sequence match: TIGRFAMs TIGR02274 match 1

SIP3334ADF56A9CDDC0
type: Structured Name
full name: dCTP deaminase
ec name: 3.5.4.13

SIP8B976E765BA78420
type: Structured Name
full name: Deoxycytidine triphosphate deaminase

dcd
type: Gene
locus name: AFE_2660

SIP975899FC1B7FBF6B
type: Function Annotation
comment: Catalyzes the deamination of dCTP to dUTP.

SIP4A66EEED137D22E1
type: Subunit Annotation
comment: Homotrimer.

SIP8A8EB4D97C7AFBF1
type: Similarity Annotation
comment: Belongs to the dCTP deaminase family.

PRO_1000189820
type: Chain Annotation
comment: dCTP deaminase
mass: 21104
range: 18638140358538286tt1tt188

18638140358538286tt1
type: Position
type: ExactPosition
position: 1
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt188
type: Position
type: ExactPosition
position: 188
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

SIPDF3829456E084FC1
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18638140358538286tt137tt137

18638140358538286tt137
type: Position
type: ExactPosition
position: 137
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt111
type: Position
type: ExactPosition
position: 111
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt116
type: Position
type: ExactPosition
position: 116
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt135
type: Position
type: ExactPosition
position: 135
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt156
type: Position
type: ExactPosition
position: 156
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt170
type: Position
type: ExactPosition
position: 170
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18638140358538286tt180
type: Position
type: ExactPosition
position: 180
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 21104

http://purl.uniprot.org/uniprot/B7J7X4#attribution-3ABB7F69A8843C04FE288B6707F5AE21
manual: true
evidence: ECO_0000255
source: MF_00146

B5EN98
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 74
mnemonic: DCD_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP3334ADF56A9CDDC0
alternative name: SIP8B976E765BA78420
enzyme: http://purl.uniprot.org/enzyme/3.5.4.13
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP8C5F865B0DB5E49A
annotation: SIP8F9005538BC6E5CA
annotation: SIP8CA4549FAA4F38AC
annotation: SIPF7E01226529461B7
annotation: SIP70B1793811168C89
annotation: PRO_1000096402
annotation: SIPC308DE8FCB850208
annotation: SIPE6578F753A0B1DA1
annotation: SIPB317B8A4319348EC
annotation: SIPE57D0781C2F1E1FB
annotation: SIP43966E88219CEC22
annotation: SIPBD64119765CB735A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/546
classified with: http://purl.uniprot.org/keywords/547
classified with: GO_0008829
classified with: GO_0000166
classified with: GO_0006226
classified with: GO_0006229
sequence: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

B5EN98-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP3334ADF56A9CDDC0
type: Structured Name
full name: dCTP deaminase
ec name: 3.5.4.13

SIP8B976E765BA78420
type: Structured Name
full name: Deoxycytidine triphosphate deaminase

dcd
type: Gene
locus name: Lferr_2286

SIP8C5F865B0DB5E49A
type: Function Annotation
comment: Catalyzes the deamination of dCTP to dUTP.

SIPF7E01226529461B7
type: Subunit Annotation
comment: Homotrimer.

SIP70B1793811168C89
type: Similarity Annotation
comment: Belongs to the dCTP deaminase family.

PRO_1000096402
type: Chain Annotation
comment: dCTP deaminase
mass: 21104
range: 18635920244291630tt1tt188

18635920244291630tt1
type: Position
type: ExactPosition
position: 1
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt188
type: Position
type: ExactPosition
position: 188
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

SIPC308DE8FCB850208
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18635920244291630tt137tt137

18635920244291630tt137
type: Position
type: ExactPosition
position: 137
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt111
type: Position
type: ExactPosition
position: 111
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt116
type: Position
type: ExactPosition
position: 116
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt135
type: Position
type: ExactPosition
position: 135
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt156
type: Position
type: ExactPosition
position: 156
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt170
type: Position
type: ExactPosition
position: 170
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

18635920244291630tt180
type: Position
type: ExactPosition
position: 180
reference: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA

MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 21104

http://purl.uniprot.org/uniprot/B5EN98#attribution-3ABB7F69A8843C04FE288B6707F5AE21
manual: true
evidence: ECO_0000255
source: MF_00146

B7JC34
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 77
mnemonic: DER_ACIF2
old mnemonic: ENGA_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIP2330F71CA8A314DB
alternative name: SIP12F40DC05E2E52C8
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIP5524FE23B5710D08
annotation: SIP0B3C9E7CEB86DE08
annotation: SIPD31ABA57DFB3DB42
annotation: PRO_1000118634
annotation: SIPEBF06A286A8D65DE
annotation: SIP79D8038134335C0C
annotation: SIPC99C940C2DA5B404
annotation: SIP3129CD10DD7BB832
annotation: SIPBE450D6DF9D802B0
annotation: SIP95583A89E14CEFFF
annotation: SIP0DB881762FF65840
annotation: SIP4A414BC6B2110F64
annotation: SIPEC361FA79E453753
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/690
classified with: GO_0005525
classified with: GO_0042254
sequence: B7JC34-1
proteome: Chromosome

B7JC34-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG1160
type: Resource
database: eggNOG
comment: Bacteria

cd01894
type: Resource
database: CDD
comment: EngA1
signature sequence match: CDD cd01894 match 1

cd01895
type: Resource
database: CDD
comment: EngA2
signature sequence match: CDD cd01895 match 1

MF_00195
type: Resource
database: HAMAP
comment: GTPase_Der
signature sequence match: HAMAP MF 00195 match 1

IPR031166
type: Resource
database: InterPro
comment: G_ENGA

IPR006073
type: Resource
database: InterPro
comment: GTP-bd

IPR016484
type: Resource
database: InterPro
comment: GTP-bd_EngA

IPR032859
type: Resource
database: InterPro
comment: KH_dom-like

IPR015946
type: Resource
database: InterPro
comment: KH_dom-like_a/b

IPR005225
type: Resource
database: InterPro
comment: Small_GTP-bd_dom

PTHR43834:SF6
type: Resource
database: PANTHER
comment: GTP-BINDING PROTEIN ENGA
signature sequence match: PANTHER PTHR43834:SF6 match 1

PTHR43834
type: Resource
database: PANTHER
comment: GTPASE DER
signature sequence match: PANTHER PTHR43834 match 1

PF14714
type: Resource
database: Pfam
comment: KH_dom-like
signature sequence match: Pfam PF14714 match 1

PF01926
type: Resource
database: Pfam
comment: MMR_HSR1
signature sequence match: Pfam PF01926 match 1
signature sequence match: Pfam PF01926 match 2

PIRSF006485
type: Resource
database: PIRSF
comment: GTP-binding_EngA
signature sequence match: PIRSF PIRSF006485 match 1

PR00326
type: Resource
database: PRINTS
comment: GTP1OBG

TIGR03594
type: Resource
database: TIGRFAMs
comment: GTPase_EngA
signature sequence match: TIGRFAMs TIGR03594 match 1

TIGR00231
type: Resource
database: TIGRFAMs
comment: small_GTP
signature sequence match: TIGRFAMs TIGR00231 match 1
signature sequence match: TIGRFAMs TIGR00231 match 2

PS51712
type: Resource
database: PROSITE
comment: G_ENGA
signature sequence match: PROSITE PS51712 match 1
signature sequence match: PROSITE PS51712 match 2

SIP2330F71CA8A314DB
type: Structured Name
full name: GTPase Der

SIP12F40DC05E2E52C8
type: Structured Name
full name: GTP-binding protein EngA

der
type: Gene
alternative label: engA
locus name: AFE_1937

SIP5524FE23B5710D08
type: Function Annotation
comment: GTPase that plays an essential role in the late steps of ribosome biogenesis.

SIP0B3C9E7CEB86DE08
type: Subunit Annotation
comment: Associates with the 50S ribosomal subunit.

SIPD31ABA57DFB3DB42
type: Similarity Annotation
comment: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

PRO_1000118634
type: Chain Annotation
comment: GTPase Der
mass: 49847
range: 18638140557440046tt1tt449

18638140557440046tt1
type: Position
type: ExactPosition
position: 1
reference: B7JC34-1

18638140557440046tt449
type: Position
type: ExactPosition
position: 449
reference: B7JC34-1

SIPEBF06A286A8D65DE
type: Domain Extent Annotation
comment: EngA-type G 1
range: 18638140557440046tt3tt167

18638140557440046tt3
type: Position
type: ExactPosition
position: 3
reference: B7JC34-1

18638140557440046tt167
type: Position
type: ExactPosition
position: 167
reference: B7JC34-1

SIP79D8038134335C0C
type: Domain Extent Annotation
comment: EngA-type G 2
range: 18638140557440046tt178tt351

18638140557440046tt178
type: Position
type: ExactPosition
position: 178
reference: B7JC34-1

18638140557440046tt351
type: Position
type: ExactPosition
position: 351
reference: B7JC34-1

SIPC99C940C2DA5B404
type: Domain Extent Annotation
comment: KH-like
range: 18638140557440046tt352tt436

18638140557440046tt352
type: Position
type: ExactPosition
position: 352
reference: B7JC34-1

18638140557440046tt436
type: Position
type: ExactPosition
position: 436
reference: B7JC34-1

18638140557440046tt9
type: Position
type: ExactPosition
position: 9
reference: B7JC34-1

18638140557440046tt16
type: Position
type: ExactPosition
position: 16
reference: B7JC34-1

18638140557440046tt56
type: Position
type: ExactPosition
position: 56
reference: B7JC34-1

18638140557440046tt60
type: Position
type: ExactPosition
position: 60
reference: B7JC34-1

18638140557440046tt119
type: Position
type: ExactPosition
position: 119
reference: B7JC34-1

18638140557440046tt122
type: Position
type: ExactPosition
position: 122
reference: B7JC34-1

18638140557440046tt184
type: Position
type: ExactPosition
position: 184
reference: B7JC34-1

18638140557440046tt191
type: Position
type: ExactPosition
position: 191
reference: B7JC34-1

18638140557440046tt231
type: Position
type: ExactPosition
position: 231
reference: B7JC34-1

18638140557440046tt235
type: Position
type: ExactPosition
position: 235
reference: B7JC34-1

18638140557440046tt296
type: Position
type: ExactPosition
position: 296
reference: B7JC34-1

18638140557440046tt299
type: Position
type: ExactPosition
position: 299
reference: B7JC34-1

1
subclass of: CHEBI_37565

2
subclass of: CHEBI_37565

B7JC34-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 49847
value: MTAVIALVGRPNVGKSTFFNRLTRTREALVADLPGLTRDRHYGTAQFEGRQYLVVDTGGFEPEEREGLVAAMAAQTRLAITEADAICFLVDAKEGLSTQDAEIAQELRRGGKPIYLVVNKMDAKGAVSELPEFYRLGLGTPYTISAAHGHGVEPLLEAIFSDLPTSEDDTADAARKGPRIAMLGRPNVGKSTLVNTMLGEKRVLVFDEPGTTRDSIRIPYERQGKPYVMIDTAGMRRRARVGEGLEKLSVLKTLSALREADVVLLVLDARLGIAEQDAHLVGVAVELGRPIVVVVNKWDGMTPEERKAVKQELERRLDFIRYAPVYTISALHGTGVGDLYKSIDQLWIDSRRHFSTAELNRALADVIETHQPPMVGGRRIKLRYCHQGGENPITLVFHGNQLTRLPGTYKRYLESAFRRALHLEAVPLRLVFRQGENPYDPQPKNGRQH

http://purl.uniprot.org/uniprot/B7JC34#attribution-3BD876A211ED32AF99CF0E5E3E1B3BEC
manual: true
evidence: ECO_0000255
source: MF_00195

B5EJF7
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 80
mnemonic: DER_ACIF5
old mnemonic: ENGA_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIP2330F71CA8A314DB
alternative name: SIP12F40DC05E2E52C8
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIPD3FEAA0F2BE9FA5D
annotation: SIPCCAE928BB975C95C
annotation: SIP8EDB855EB82D1162
annotation: PRO_1000099083
annotation: SIP1EADB78AB6AF994E
annotation: SIPB781A6CD36E98E7A
annotation: SIPEBF39183D7D81483
annotation: SIP42C177DC0769DA8D
annotation: SIP6ECE15EE9CC24CFA
annotation: SIP67A4DD6468F97981
annotation: SIPE8D662569303F4A5
annotation: SIP90D0782D8BFC4595
annotation: SIPA5B1E128E1D50ED4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/690
classified with: GO_0005525
classified with: GO_0042254
sequence: B5EJF7-1

B5EJF7-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIP2330F71CA8A314DB
type: Structured Name
full name: GTPase Der

SIP12F40DC05E2E52C8
type: Structured Name
full name: GTP-binding protein EngA

der
type: Gene
alternative label: engA
locus name: Lferr_1609

SIPD3FEAA0F2BE9FA5D
type: Function Annotation
comment: GTPase that plays an essential role in the late steps of ribosome biogenesis.

SIPCCAE928BB975C95C
type: Subunit Annotation
comment: Associates with the 50S ribosomal subunit.

SIP8EDB855EB82D1162
type: Similarity Annotation
comment: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

PRO_1000099083
type: Chain Annotation
comment: GTPase Der
mass: 49847
range: 18635920178034478tt1tt449

18635920178034478tt1
type: Position
type: ExactPosition
position: 1
reference: B5EJF7-1

18635920178034478tt449
type: Position
type: ExactPosition
position: 449
reference: B5EJF7-1

SIP1EADB78AB6AF994E
type: Domain Extent Annotation
comment: EngA-type G 1
range: 18635920178034478tt3tt167

18635920178034478tt3
type: Position
type: ExactPosition
position: 3
reference: B5EJF7-1

18635920178034478tt167
type: Position
type: ExactPosition
position: 167
reference: B5EJF7-1

SIPB781A6CD36E98E7A
type: Domain Extent Annotation
comment: EngA-type G 2
range: 18635920178034478tt178tt351

18635920178034478tt178
type: Position
type: ExactPosition
position: 178
reference: B5EJF7-1

18635920178034478tt351
type: Position
type: ExactPosition
position: 351
reference: B5EJF7-1

SIPEBF39183D7D81483
type: Domain Extent Annotation
comment: KH-like
range: 18635920178034478tt352tt436

18635920178034478tt352
type: Position
type: ExactPosition
position: 352
reference: B5EJF7-1

18635920178034478tt436
type: Position
type: ExactPosition
position: 436
reference: B5EJF7-1

18635920178034478tt9
type: Position
type: ExactPosition
position: 9
reference: B5EJF7-1

18635920178034478tt16
type: Position
type: ExactPosition
position: 16
reference: B5EJF7-1

18635920178034478tt56
type: Position
type: ExactPosition
position: 56
reference: B5EJF7-1

18635920178034478tt60
type: Position
type: ExactPosition
position: 60
reference: B5EJF7-1

18635920178034478tt119
type: Position
type: ExactPosition
position: 119
reference: B5EJF7-1

18635920178034478tt122
type: Position
type: ExactPosition
position: 122
reference: B5EJF7-1

18635920178034478tt184
type: Position
type: ExactPosition
position: 184
reference: B5EJF7-1

18635920178034478tt191
type: Position
type: ExactPosition
position: 191
reference: B5EJF7-1

18635920178034478tt231
type: Position
type: ExactPosition
position: 231
reference: B5EJF7-1

18635920178034478tt235
type: Position
type: ExactPosition
position: 235
reference: B5EJF7-1

18635920178034478tt296
type: Position
type: ExactPosition
position: 296
reference: B5EJF7-1

18635920178034478tt299
type: Position
type: ExactPosition
position: 299
reference: B5EJF7-1

1
subclass of: CHEBI_37565

2
subclass of: CHEBI_37565

B5EJF7-1
type: Simple Sequence
modified: 2008-10-14
version: 1
mass: 49847
value: MTAVIALVGRPNVGKSTFFNRLTRTREALVADLPGLTRDRHYGTAQFEGRQYLVVDTGGFEPEEREGLVAAMAAQTRLAITEADAICFLVDAKEGLSTQDAEIAQELRRGGKPIYLVVNKMDAKGAVSELPEFYRLGLGTPYTISAAHGHGVEPLLEAIFSDLPTSEDDTADAARKGPRIAMLGRPNVGKSTLVNTMLGEKRVLVFDEPGTTRDSIRIPYERQGKPYVMIDTAGMRRRARVGEGLEKLSVLKTLSALREADVVLLVLDARLGIAEQDAHLVGVAVELGRPIVVVVNKWDGMTPEERKAVKQELERRLDFIRYAPVYTISALHGTGVGDLYKSIDQLWIDSRRHFSTAELNRALADVIETHQPPMVGGRRIKLRYCHQGGENPITLVFHGNQLTRLPGTYKRYLESAFRRALHLEAVPLRLVFRQGENPYDPQPKNGRQH

http://purl.uniprot.org/uniprot/B5EJF7#attribution-3BD876A211ED32AF99CF0E5E3E1B3BEC
manual: true
evidence: ECO_0000255
source: MF_00195

B7J7X8
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 78
mnemonic: DNAJ_ACIF2
citation: http://purl.uniprot.org/citations/19077236
recommended name: SIPAB5D6734BF88C1A0
organism: http://purl.uniprot.org/taxonomy/243159
annotation: SIPB01DE12B9AC93042
annotation: SIPEB822388A5E0E26E
annotation: SIP9CF0CC5E695A4B9B
annotation: SIPC86EBF327ACD6D82
annotation: SIPC04C80CBAACBDDA8
annotation: SIP2CA8FE040B6307C9
annotation: PRO_1000137653
annotation: SIP7E01C610EFF04418
annotation: SIP67BFC5EF119AD5BB
annotation: SIPD163F7349015D15C
annotation: SIP43E0C9205647C2AA
annotation: SIP271AACC004364CCF
annotation: SIP52949B7B6F118F5A
annotation: SIP4D4401F0CD977BC6
annotation: SIPE5B41C352A0EC0FE
annotation: SIP1204444433AB1286
annotation: SIP9553B106BDD1858A
annotation: SIP6AE3CE9CB762A9E3
annotation: SIPC39ADC312BB9871A
annotation: SIP25A4947601851AF0
annotation: SIPF21C7873A2C4D2D7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/346
classified with: http://purl.uniprot.org/keywords/863
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0031072
classified with: GO_0051082
classified with: GO_0008270
classified with: GO_0006260
classified with: GO_0006457
classified with: GO_0009408
sequence: B7J7X8-1
proteome: Chromosome

B7J7X8-citation-19077236
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
type: Strain

COG0484
type: Resource
database: eggNOG
comment: Bacteria

cd06257
type: Resource
database: CDD
comment: DnaJ
signature sequence match: CDD cd06257 match 1

cd10747
type: Resource
database: CDD
comment: DnaJ_C
signature sequence match: CDD cd10747 match 1

cd10719
type: Resource
database: CDD
comment: DnaJ_zf
signature sequence match: CDD cd10719 match 1

http://purl.uniprot.org/gene3d/1.10.287.110
type: Resource
database: Gene3D
comment: DnaJ domain
signature sequence match: Gene3D 1.10.287.110 match 1

http://purl.uniprot.org/gene3d/2.10.230.10
type: Resource
database: Gene3D
comment: Heat shock protein DnaJ, cysteine-rich domain
signature sequence match: Gene3D 2.10.230.10 match 1

http://purl.uniprot.org/gene3d/2.60.260.20
type: Resource
database: Gene3D
comment: Urease metallochaperone UreE, N-terminal domain
signature sequence match: Gene3D 2.60.260.20 match 1
signature sequence match: Gene3D 2.60.260.20 match 2

MF_01152
type: Resource
database: HAMAP
comment: DnaJ
signature sequence match: HAMAP MF 01152 match 1

IPR012724
type: Resource
database: InterPro
comment: DnaJ

IPR002939
type: Resource
database: InterPro
comment: DnaJ_C

IPR001623
type: Resource
database: InterPro
comment: DnaJ_domain

IPR018253
type: Resource
database: InterPro
comment: DnaJ_domain_CS

IPR008971
type: Resource
database: InterPro
comment: HSP40/DnaJ_pept-bd

IPR001305
type: Resource
database: InterPro
comment: HSP_DnaJ_Cys-rich_dom

IPR036410
type: Resource
database: InterPro
comment: HSP_DnaJ_Cys-rich_dom_sf

IPR036869
type: Resource
database: InterPro
comment: J_dom_sf

PTHR43096:SF48
type: Resource
database: PANTHER
comment: CHAPERONE PROTEIN DNAJ
signature sequence match: PANTHER PTHR43096:SF48 match 1

PTHR43096
type: Resource
database: PANTHER
comment: DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED
signature sequence match: PANTHER PTHR43096 match 1

PF00226
type: Resource
database: Pfam
comment: DnaJ
signature sequence match: Pfam PF00226 match 1

PF01556
type: Resource
database: Pfam
comment: DnaJ_C
signature sequence match: Pfam PF01556 match 1

PF00684
type: Resource
database: Pfam
comment: DnaJ_CXXCXGXG
signature sequence match: Pfam PF00684 match 1

PR00625
type: Resource
database: PRINTS
comment: JDOMAIN

SM00271
type: Resource
database: SMART
comment: DnaJ
signature sequence match: SMART SM00271 match 1

SSF46565
type: Resource
database: SUPFAM
comment: Chaperone J-domain
signature sequence match: SUPFAM SSF46565 match 1

SSF57938
type: Resource
database: SUPFAM
comment: DnaJ/Hsp40 cysteine-rich domain
signature sequence match: SUPFAM SSF57938 match 1

SSF49493
type: Resource
database: SUPFAM
comment: HSP40/DnaJ peptide-binding domain
signature sequence match: SUPFAM SSF49493 match 1
signature sequence match: SUPFAM SSF49493 match 2

TIGR02349
type: Resource
database: TIGRFAMs
comment: DnaJ_bact
signature sequence match: TIGRFAMs TIGR02349 match 1

PS00636
type: Resource
database: PROSITE
comment: DNAJ_1
signature sequence match: PROSITE PS00636 match 1

PS50076
type: Resource
database: PROSITE
comment: DNAJ_2
signature sequence match: PROSITE PS50076 match 1

PS51188
type: Resource
database: PROSITE
comment: ZF_CR
signature sequence match: PROSITE PS51188 match 1

SIPAB5D6734BF88C1A0
type: Structured Name
full name: Chaperone protein DnaJ

dnaJ
type: Gene
locus name: AFE_2664

SIPB01DE12B9AC93042
type: Function Annotation
comment: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.

SIPEB822388A5E0E26E
type: Cofactor Annotation
comment: Binds 2 Zn(2+) ions per monomer.
cofactor: CHEBI_29105

SIP9CF0CC5E695A4B9B
type: Subunit Annotation
comment: Homodimer.

SIPC04C80CBAACBDDA8
type: Domain Annotation
comment: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

SIP2CA8FE040B6307C9
type: Similarity Annotation
comment: Belongs to the DnaJ family.

PRO_1000137653
type: Chain Annotation
comment: Chaperone protein DnaJ
mass: 40516
range: 18638140358539310tt1tt375

18638140358539310tt1
type: Position
type: ExactPosition
position: 1
reference: B7J7X8-1

18638140358539310tt375
type: Position
type: ExactPosition
position: 375
reference: B7J7X8-1

SIP7E01C610EFF04418
type: Domain Extent Annotation
comment: J
range: 18638140358539310tt5tt70

18638140358539310tt5
type: Position
type: ExactPosition
position: 5
reference: B7J7X8-1

18638140358539310tt70
type: Position
type: ExactPosition
position: 70
reference: B7J7X8-1

SIP67BFC5EF119AD5BB
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18638140358539310tt146tt153

18638140358539310tt146
type: Position
type: ExactPosition
position: 146
reference: B7J7X8-1

18638140358539310tt153
type: Position
type: ExactPosition
position: 153
reference: B7J7X8-1

SIPD163F7349015D15C
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18638140358539310tt163tt170

18638140358539310tt163
type: Position
type: ExactPosition
position: 163
reference: B7J7X8-1

18638140358539310tt170
type: Position
type: ExactPosition
position: 170
reference: B7J7X8-1

SIP43E0C9205647C2AA
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18638140358539310tt185tt192

18638140358539310tt185
type: Position
type: ExactPosition
position: 185
reference: B7J7X8-1

18638140358539310tt192
type: Position
type: ExactPosition
position: 192
reference: B7J7X8-1

SIP271AACC004364CCF
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18638140358539310tt199tt206

18638140358539310tt199
type: Position
type: ExactPosition
position: 199
reference: B7J7X8-1

18638140358539310tt206
type: Position
type: ExactPosition
position: 206
reference: B7J7X8-1

SIP52949B7B6F118F5A
type: Zinc Finger Annotation
comment: CR-type
range: 18638140358539310tt133tt211

18638140358539310tt133
type: Position
type: ExactPosition
position: 133
reference: B7J7X8-1

18638140358539310tt211
type: Position
type: ExactPosition
position: 211
reference: B7J7X8-1

18638140358539310tt149
type: Position
type: ExactPosition
position: 149
reference: B7J7X8-1

18638140358539310tt166
type: Position
type: ExactPosition
position: 166
reference: B7J7X8-1

18638140358539310tt188
type: Position
type: ExactPosition
position: 188
reference: B7J7X8-1

18638140358539310tt202
type: Position
type: ExactPosition
position: 202
reference: B7J7X8-1

1
subclass of: CHEBI_29105

2
subclass of: CHEBI_29105

B7J7X8-1
type: Simple Sequence
modified: 2009-02-10
version: 1
mass: 40516
value: MATRDYYEVLEISRTADDGEIKKSYRRLAMRYHPDRNPDDASAEERFKEISAAYEVLSDPQKRQAYDRFGHAGVNGGGGGPGAGFGGGGGGFGDVFSDLFEQAFGGGFRGQDSGRGADLRYELELTLEEAALGKEVTIQIPSSATCEVCRGSGAKPGSAVEDCATCGGRGQVRMVQGFFSVTRPCPQCNGSGKVIKEPCTNCHGHGRVRRNRDLQVKVPAGVDTGDRIRLNGEGEAGERGGPAGDLYIQVRVLPHALFERDGDDLHCAVPVQFTTMAMGGELEVPTLTGRAKVQIAPGTQSGAVFRLRGKGIKGVRSKLNGDLHCQLQVEVPVHLSARQKELLEEFAREGGDNIQHPQQESWWNKAKDFFDRMGL

http://purl.uniprot.org/uniprot/B7J7X8#attribution-91DEEFF61680FB8F8CA288D6901560AE
manual: true
evidence: ECO_0000255
source: MF_01152

B5ENA2
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 85
mnemonic: DNAJ_ACIF5
citation: SIP952ED53E42E68AC1
recommended name: SIPAB5D6734BF88C1A0
organism: http://purl.uniprot.org/taxonomy/380394
annotation: SIP67530082B3AD199D
annotation: SIP72DC67366F63A76A
annotation: SIP1F8CCAD178E0153D
annotation: SIPD3497856EC462218
annotation: SIP7C25C318FFCC05D5
annotation: SIPF7465E81ED4C53C9
annotation: PRO_1000137654
annotation: SIP4A71E7D632A4CD21
annotation: SIPB3A2C4B1F37FFED0
annotation: SIP7D652546DDBDC22C
annotation: SIP6A0F49D00540600B
annotation: SIP801F2FF28D52529F
annotation: SIP15B19E5E02F88F13
annotation: SIP0F1A7C2AA0C70107
annotation: SIPBD88D0743B9659AD
annotation: SIP94E14B4D5378302B
annotation: SIP5F99D54D71742C64
annotation: SIP6F00B89987CED611
annotation: SIP1EF9A7DC30F8F23F
annotation: SIPB7FB4A4CF6977662
annotation: SIPC741762EEF2FC8F6
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/346
classified with: http://purl.uniprot.org/keywords/863
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0031072
classified with: GO_0051082
classified with: GO_0008270
classified with: GO_0006260
classified with: GO_0006457
classified with: GO_0009408
sequence: B5ENA2-1

B5ENA2-citation-SIP952ED53E42E68AC1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 53993 / BNL-5-31
type: Strain

SIPAB5D6734BF88C1A0
type: Structured Name
full name: Chaperone protein DnaJ

dnaJ
type: Gene
locus name: Lferr_2290

SIP67530082B3AD199D
type: Function Annotation
comment: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.

SIP72DC67366F63A76A
type: Cofactor Annotation
comment: Binds 2 Zn(2+) ions per monomer.
cofactor: CHEBI_29105

SIP1F8CCAD178E0153D
type: Subunit Annotation
comment: Homodimer.

SIP7C25C318FFCC05D5
type: Domain Annotation
comment: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

SIPF7465E81ED4C53C9
type: Similarity Annotation
comment: Belongs to the DnaJ family.

PRO_1000137654
type: Chain Annotation
comment: Chaperone protein DnaJ
mass: 40516
range: 18635920244814382tt1tt375

18635920244814382tt1
type: Position
type: ExactPosition
position: 1
reference: B5ENA2-1

18635920244814382tt375
type: Position
type: ExactPosition
position: 375
reference: B5ENA2-1

SIP4A71E7D632A4CD21
type: Domain Extent Annotation
comment: J
range: 18635920244814382tt5tt70

18635920244814382tt5
type: Position
type: ExactPosition
position: 5
reference: B5ENA2-1

18635920244814382tt70
type: Position
type: ExactPosition
position: 70
reference: B5ENA2-1

SIPB3A2C4B1F37FFED0
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18635920244814382tt146tt153

18635920244814382tt146
type: Position
type: ExactPosition
position: 146
reference: B5ENA2-1

18635920244814382tt153
type: Position
type: ExactPosition
position: 153
reference: B5ENA2-1

SIP7D652546DDBDC22C
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18635920244814382tt163tt170

18635920244814382tt163
type: Position
type: ExactPosition
position: 163
reference: B5ENA2-1

18635920244814382tt170
type: Position
type: ExactPosition
position: 170
reference: B5ENA2-1

SIP6A0F49D00540600B
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18635920244814382tt185tt192

18635920244814382tt185
type: Position
type: ExactPosition
position: 185
reference: B5ENA2-1

18635920244814382tt192
type: Position
type: ExactPosition
position: 192
reference: B5ENA2-1

SIP801F2FF28D52529F
type: Repeat Annotation
comment: CXXCXGXG motif
range: 18635920244814382tt199tt206

18635920244814382tt199
type: Position
type: ExactPosition
position: 199
reference: B5ENA2-1

18635920244814382tt206
type: Position
type: ExactPosition
position: 206
reference: B5ENA2-1

SIP15B19E5E02F88F13
type: Zinc Finger Annotation
comment: CR-type
range: 18635920244814382tt133tt211

18635920244814382tt133
type: Position
type: ExactPosition
position: 133
reference: B5ENA2-1