A0A060N0V5
type: Protein
reviewed: false
created: 2014-09-03
modified: 2023-02-22
version: 17
mnemonic: A0A060N0V5_9EUKA
citation: SIP8957282E9CE978E6
submitted name: SIP19F6306D51C4AC72
organism: http://purl.uniprot.org/taxonomy/85707
annotation: SIPA5AE16B26E1EF906
annotation: SIPD26D6229225AA5FA
existence: Evidence at Transcript Level Existence
classified with: http://purl.uniprot.org/keywords/251
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0003746
sequence: A0A060N0V5-1

SIP8957282E9CE978E6
type: Submission Citation
title: Evolution of elongation factor 1alpha and elongation factor-like genes in eukaryotes.
author: Kamikawa R.
author: Inagaki Y.
date: 2012-11
submitted to: EMBL/GenBank/DDBJ

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

CCAP 1958/3
type: Strain

cd01883
type: Resource
database: CDD
comment: EF1_alpha
signature sequence match: CDD cd01883 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1

IPR031157
type: Resource
database: InterPro
comment: G_TR_CS

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

IPR000795
type: Resource
database: InterPro
comment: T_Tr_GTP-bd_dom

PTHR23115:SF224
type: Resource
database: PANTHER
comment: TRANSLATION ELONGATION FACTOR ALPHA
signature sequence match: PANTHER PTHR23115:SF224 match 1

PTHR23115
type: Resource
database: PANTHER
comment: TRANSLATION FACTOR
signature sequence match: PANTHER PTHR23115 match 1

PF00009
type: Resource
database: Pfam
comment: GTP_EFTU
signature sequence match: Pfam PF00009 match 1

PR00315
type: Resource
database: PRINTS
comment: ELONGATNFCT

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1

PS00301
type: Resource
database: PROSITE
comment: G_TR_1
signature sequence match: PROSITE PS00301 match 1

PS51722
type: Resource
database: PROSITE
comment: G_TR_2
signature sequence match: PROSITE PS51722 match 1

SIP19F6306D51C4AC72
type: Structured Name
full name: Elongation factor-like protein

EFL
type: Gene

SIPA5AE16B26E1EF906
type: Domain Extent Annotation
comment: Tr-type G
range: -9218586547919940562tt11tt258

-9218586547919940562tt11
type: Position
type: ExactPosition
position: 11
reference: A0A060N0V5-1

-9218586547919940562tt258
type: Position
type: ExactPosition
position: 258
reference: A0A060N0V5-1

-9218586547919940562tt275
type: Position
type: ExactPosition
position: 275
reference: A0A060N0V5-1

A0A060N0V5-1
type: Simple Sequence
modified: 2014-09-03
version: 1
fragment: single
mass: 30467
value: MTDAVSATDGKDHLSIVICGHVDSGKSTTTGRLLFELGGIPEREMQKLKDEAGRLGKSSFAFAFYMDRQKDERERGVTISCTTKEFFTDKWHYTIIDAPGHRDFIKNMISGAAQADVALLMVPADGNFTTAIQKGDHKAGEIQGQTRQHARLLNLLGVKQLIIGINKMDADIAGYKEARYIEIRDEMRDMLGRVGWKKDFIADQVPVLPISGWIGDNLLSKSTNMPWWSGVDIKNNAGVALHINCLLDALNDMACLPSRKTEAPMRVPISGIYKI

V9I190
type: Protein
reviewed: false
created: 2014-03-19
modified: 2023-02-22
version: 24
mnemonic: V9I190_9EUKA
citation: SIPEB01C8CE8EFAE55C
recommended name: SIPAC6946E25126E43E
enzyme: http://purl.uniprot.org/enzyme/2.7.7.6
organism: http://purl.uniprot.org/taxonomy/85707
annotation: SIP3BC5BF145FFCC4D0
annotation: SIPB624725DC1E7BC26
annotation: SIPAAC48584DE69B76C
annotation: SIPE25CF4AB762AFE9D
annotation: SIPC3F441CEDF9FAACE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/240
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/548
classified with: GO_0000428
classified with: GO_0003677
classified with: GO_0003899
classified with: GO_0006351
sequence: V9I190-1

SIPEB01C8CE8EFAE55C
type: Submission Citation
title: Evolutionary relationships of diverse free-living protists among eukaryotes inferred using Rpb1, the largest subunit of RNA polymerase II.
author: Malik S.-B.
author: Brochu C.D.
author: Yuan J.
author: Whetstone A.
author: Morse G.J.
author: McKiernan K.R.
author: Sebastian N.
author: Logsdon J.M.Jr.
date: 2010-12
submitted to: EMBL/GenBank/DDBJ

V9I190-citation-SIPEB01C8CE8EFAE55C
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

cd02584
type: Resource
database: CDD
comment: RNAP_II_Rpb1_C
signature sequence match: CDD cd02584 match 1

http://purl.uniprot.org/gene3d/1.10.274.100
type: Resource
database: Gene3D
comment: RNA polymerase Rpb1, domain 3
signature sequence match: Gene3D 1.10.274.100 match 1

IPR045867
type: Resource
database: InterPro
comment: DNA-dir_RpoC_beta_prime

IPR000722
type: Resource
database: InterPro
comment: RNA_pol_asu

IPR006592
type: Resource
database: InterPro
comment: RNA_pol_N

IPR007066
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_3

IPR042102
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_3_sf

IPR007083
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_4

IPR007081
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_5

IPR007075
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_6

IPR007073
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_7

IPR038593
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_7_sf

IPR038120
type: Resource
database: InterPro
comment: Rpb1_funnel_sf

PTHR19376
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE
signature sequence match: PANTHER PTHR19376 match 1

PTHR19376:SF37
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
signature sequence match: PANTHER PTHR19376:SF37 match 1

PF00623
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_2
signature sequence match: Pfam PF00623 match 1

PF04983
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_3
signature sequence match: Pfam PF04983 match 1

PF05000
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_4
signature sequence match: Pfam PF05000 match 1

PF04998
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_5
signature sequence match: Pfam PF04998 match 1

PF04992
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_6
signature sequence match: Pfam PF04992 match 1

PF04990
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_7
signature sequence match: Pfam PF04990 match 1

SM00663
type: Resource
database: SMART
comment: RPOLA_N
signature sequence match: SMART SM00663 match 1

SSF64484
type: Resource
database: SUPFAM
comment: beta and beta-prime subunits of DNA dependent RNA-polymerase
signature sequence match: SUPFAM SSF64484 match 1

SIPAC6946E25126E43E
type: Structured Name
full name: DNA-directed RNA polymerase
ec name: 2.7.7.6

Rpb1
type: Gene

SIPB624725DC1E7BC26
type: Similarity Annotation
comment: Belongs to the RNA polymerase beta' chain family.

SIPAAC48584DE69B76C
type: Domain Extent Annotation
comment: RNA polymerase N-terminal
range: 24269834518343726tt1tt87

24269834518343726tt1
type: Position
type: ExactPosition
position: 1
reference: V9I190-1

24269834518343726tt87
type: Position
type: ExactPosition
position: 87
reference: V9I190-1

24269834518343726tt963
type: Position
type: ExactPosition
position: 963
reference: V9I190-1

V9I190-1
type: Simple Sequence
modified: 2014-03-19
version: 1
fragment: single
mass: 107880
value: SLHKMSIMGHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNMHVAQSSETRAEVREIMMVPRQIVSPQANKPVIGLVQDALLACSKFTRRDTFIERDLMMNICMWLPDFDGKMPQPAILKPKPLWTGKQLFSLIIPAVNLEIAPGGADRSHPDFAMTPVDNRVLIVNGEVLSGILTKSTLGTSGVGLVHTTWKEYGPDGAKRFLNSAQVVVNYWLQNTGFSIGIGDTIADAETMGQINEAIHEAKVQVKEYVRMAQERKLASEPGKTVMESFEGKVNKVLNTARDKAGKNAEDSLAVHNNVKAMVTAGSKGSYINISQMIACVGQQNVEGKRIPYGFRKRTLPHFTKDDLGPEARGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAKTGYIQRRLVKSMEDVSVMYDGTVRNSMGKIIQFLYGEDGMDGTSHEDQIIPHLRPSDARVSEMYEWDVDAAAFGRGVLNREIIDDVRDSAASRQLLKEEFEELQGDRALLREYVLTDGEEKWPMPINLSRLIWNARTLHGIDGMEPSDLNPSVIVETIRHLTRTLVVVPGEDQTSKEAQMNATIMLFSLIRGTLASKRVIHEYHLTKDAFLWLVGEISEKFAQAMVHPGEMIGAIAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLEELINVSRSPKTPSLVVYLEETYANDSDLAKRVQTSLEYTCLADVTSEVEVHYDPDLKNTTIEADRELVRSYYEMPDDDLDMDKISPWLLRIVLDGKRIYDKDLKMDYITQCINETFPADFHVIYSDDNAEQLVIHLRLKSEEDQKGADEEDDILGQGDDVWLQDNMAAILSLTKLRGVANIKKVFMDERKRVAIDSVTGEFSTRTEWFLDTEGTNMLEVMSMPGVDYTRIEPNDVYESLPVLGIEGARGVLLFQIRAVLKGSGGSYVNYRHLAMLVDVMCFRGYLMAITRHGINRVDSGPLMR

A0A2R4IKW1
type: Protein
reviewed: false
created: 2018-06-20
modified: 2023-05-03
version: 13
mnemonic: A0A2R4IKW1_9EUKA
citation: http://purl.uniprot.org/citations/29588502
citation: SIP4C817A4A6F379F2F
submitted name: SIPE8386DC0D0A1E038
organism: http://purl.uniprot.org/taxonomy/554453
existence: Predicted Existence
classified with: GO_0016020
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0007165
sequence: A0A2R4IKW1-1

A0A2R4IKW1-citation-29588502
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

SIP4C817A4A6F379F2F
type: Submission Citation
author: Cohen D.B.
author: Kent A.D.
date: 2018-02
submitted to: EMBL/GenBank/DDBJ

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

IPR005225
type: Resource
database: InterPro
comment: Small_GTP-bd_dom

IPR001806
type: Resource
database: InterPro
comment: Small_GTPase

IPR020849
type: Resource
database: InterPro
comment: Small_GTPase_Ras-type

PTHR24070:SF226
type: Resource
database: PANTHER
comment: GTP-BINDING PROTEIN RHEB HOMOLOG
signature sequence match: PANTHER PTHR24070:SF226 match 1

PTHR24070
type: Resource
database: PANTHER
comment: RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY
signature sequence match: PANTHER PTHR24070 match 1

PF00071
type: Resource
database: Pfam
comment: Ras
signature sequence match: Pfam PF00071 match 1

PR00449
type: Resource
database: PRINTS
comment: RASTRNSFRMNG

SM00175
type: Resource
database: SMART
comment: RAB
signature sequence match: SMART SM00175 match 1

SM00173
type: Resource
database: SMART
comment: RAS
signature sequence match: SMART SM00173 match 1

SM00174
type: Resource
database: SMART
comment: RHO
signature sequence match: SMART SM00174 match 1

TIGR00231
type: Resource
database: TIGRFAMs
comment: small_GTP
signature sequence match: TIGRFAMs TIGR00231 match 1

PS51419
type: Resource
database: PROSITE
comment: RAB
signature sequence match: PROSITE PS51419 match 1

PS51421
type: Resource
database: PROSITE
comment: RAS
signature sequence match: PROSITE PS51421 match 1

PS51420
type: Resource
database: PROSITE
comment: RHO
signature sequence match: PROSITE PS51420 match 1

SIPE8386DC0D0A1E038
type: Structured Name
full name: Rheb

A0A2R4IKW1-1
type: Simple Sequence
modified: 2018-06-20
version: 1
mass: 23600
value: MPFCCPPSNDDKAVAALDADDSTAPLAGGRRRRNIQQKRKIVVLGFRGVGKSAVTIQFCENHFADMYHPTIENTFERTVQLGSEEFTVQVVDTAGQDEYSVFPSQYSVGVDGYLLVYSIASKSSLQMIKVLNDKILNAAGVESVPRVLIGNKCDMGARRQVTVEDGQRLAAQWGCSHMEVSAKHNQHIEEAFMGVLAEIEKSRAPAVEEKSCSLM

A1KYY6
type: Protein
reviewed: false
created: 2007-02-06
modified: 2023-02-22
version: 40
mnemonic: A1KYY6_9EUKA
citation: SIPFEE3CCDA8131433D
submitted name: SIPF88D9215D3C90935
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP491216289EC394AC
annotation: SIPD742ED065CBE08E9
annotation: SIP3EE567F040522DD1
existence: Predicted Existence
classified with: http://purl.uniprot.org/keywords/251
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0003746
sequence: KYAWVLDKLKAERERGITIDIGLWKFESTKFEYTIIDAPGHRDFVKNMITGTSQADVAVLVVAAGQGEFEAGFSKEGQTREHALLVFTLGVKQVIVAVNKMDDKSVNYSKARFDEVQEEVATYLRKVGYNPATIPFVPISGWSGDNMTEPSANMPWYSGPTLLGALDACEVPKRHADKPLRLPL

SIPFEE3CCDA8131433D
type: Submission Citation
title: Protistan origins of animals and fungi.
author: Steenkamp E.T.
date: 2004-10
submitted to: EMBL/GenBank/DDBJ

A1KYY6-citation-SIPFEE3CCDA8131433D
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

PTHR23115:SF170
type: Resource
database: PANTHER
comment: ELONGATION FACTOR 1-ALPHA 2
signature sequence match: PANTHER PTHR23115:SF170 match 1

SIPF88D9215D3C90935
type: Structured Name
full name: Elongation factor 1 alpha

ef1a
type: Gene

SIP491216289EC394AC
type: Domain Extent Annotation
comment: Tr-type G
range: 18350073177519662tt1tt173

18350073177519662tt1
type: Position
type: ExactPosition
position: 1
reference: KYAWVLDKLKAERERGITIDIGLWKFESTKFEYTIIDAPGHRDFVKNMITGTSQADVAVLVVAAGQGEFEAGFSKEGQTREHALLVFTLGVKQVIVAVNKMDDKSVNYSKARFDEVQEEVATYLRKVGYNPATIPFVPISGWSGDNMTEPSANMPWYSGPTLLGALDACEVPKRHADKPLRLPL

18350073177519662tt173
type: Position
type: ExactPosition
position: 173
reference: KYAWVLDKLKAERERGITIDIGLWKFESTKFEYTIIDAPGHRDFVKNMITGTSQADVAVLVVAAGQGEFEAGFSKEGQTREHALLVFTLGVKQVIVAVNKMDDKSVNYSKARFDEVQEEVATYLRKVGYNPATIPFVPISGWSGDNMTEPSANMPWYSGPTLLGALDACEVPKRHADKPLRLPL

18350073177519662tt184
type: Position
type: ExactPosition
position: 184
reference: KYAWVLDKLKAERERGITIDIGLWKFESTKFEYTIIDAPGHRDFVKNMITGTSQADVAVLVVAAGQGEFEAGFSKEGQTREHALLVFTLGVKQVIVAVNKMDDKSVNYSKARFDEVQEEVATYLRKVGYNPATIPFVPISGWSGDNMTEPSANMPWYSGPTLLGALDACEVPKRHADKPLRLPL

KYAWVLDKLKAERERGITIDIGLWKFESTKFEYTIIDAPGHRDFVKNMITGTSQADVAVLVVAAGQGEFEAGFSKEGQTREHALLVFTLGVKQVIVAVNKMDDKSVNYSKARFDEVQEEVATYLRKVGYNPATIPFVPISGWSGDNMTEPSANMPWYSGPTLLGALDACEVPKRHADKPLRLPL
type: Simple Sequence
modified: 2007-02-06
version: 1
fragment: single
mass: 20434

Q3LZH9
type: Protein
reviewed: false
created: 2005-10-25
modified: 2023-02-22
version: 32
mnemonic: Q3LZH9_9EUKA
citation: http://purl.uniprot.org/citations/16171183
submitted name: SIPA1F34214C4CB2266
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP5BB73C8FF04B146F
annotation: SIP8F2C55C2E7C06B7E
annotation: SIPA7A9759D147EBF61
annotation: SIPE7D9C3E6522F8E07
existence: Predicted Existence
sequence: QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI

Q3LZH9-citation-16171183
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

IPR000626
type: Resource
database: InterPro
comment: Ubiquitin-like_dom

IPR029071
type: Resource
database: InterPro
comment: Ubiquitin-like_domsf

IPR019956
type: Resource
database: InterPro
comment: Ubiquitin_dom

PTHR10666:SF437
type: Resource
database: PANTHER
comment: POLYUBIQUITIN-B
signature sequence match: PANTHER PTHR10666:SF437 match 1

PTHR10666
type: Resource
database: PANTHER
comment: UBIQUITIN
signature sequence match: PANTHER PTHR10666 match 1

PF00240
type: Resource
database: Pfam
comment: ubiquitin
signature sequence match: Pfam PF00240 match 1
signature sequence match: Pfam PF00240 match 2

PR00348
type: Resource
database: PRINTS
comment: UBIQUITIN

SSF54236
type: Resource
database: SUPFAM
comment: Ubiquitin-like
signature sequence match: SUPFAM SSF54236 match 1
signature sequence match: SUPFAM SSF54236 match 2

PS50053
type: Resource
database: PROSITE
comment: UBIQUITIN_2
signature sequence match: PROSITE PS50053 match 1
signature sequence match: PROSITE PS50053 match 2

SIPA1F34214C4CB2266
type: Structured Name
full name: Polyubiquitin

pub
type: Gene

SIP5BB73C8FF04B146F
type: Domain Extent Annotation
comment: Ubiquitin-like
range: 22855876138776878tt1tt28

22855876138776878tt1
type: Position
type: ExactPosition
position: 1
reference: QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI

22855876138776878tt28
type: Position
type: ExactPosition
position: 28
reference: QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI

SIP8F2C55C2E7C06B7E
type: Domain Extent Annotation
comment: Ubiquitin-like
range: 22855876138776878tt29tt64

22855876138776878tt29
type: Position
type: ExactPosition
position: 29
reference: QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI

22855876138776878tt64
type: Position
type: ExactPosition
position: 64
reference: QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI

QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSDSIENVKAKIQDKEGI
type: Simple Sequence
modified: 2005-10-25
version: 1
fragment: single
mass: 7185

B3SHP3
type: Protein
reviewed: false
created: 2008-09-02
modified: 2023-02-22
version: 60
mnemonic: B3SHP3_9EUKA
citation: http://purl.uniprot.org/citations/18205932
recommended name: SIP4216B33C8D2C6461
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP0BE48F17A9449180
annotation: SIP86B2D9341E52AABA
annotation: SIP2F1562DBB1DC89F5
annotation: SIP5C8800CEFFFF1E9F
annotation: SIP58D2F66AECCEDCC2
annotation: SIPE046163AEACA6679
annotation: SIPF3DF52255AF4DF03
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/493
classified with: GO_0005874
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0005200
classified with: GO_0007017
sequence: B3SHP3-1

B3SHP3-citation-18205932
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

cd02187
type: Resource
database: CDD
comment: beta_tubulin
signature sequence match: CDD cd02187 match 1

http://purl.uniprot.org/gene3d/1.10.287.600
type: Resource
database: Gene3D
comment: Helix hairpin bin
signature sequence match: Gene3D 1.10.287.600 match 1

http://purl.uniprot.org/gene3d/3.30.1330.20
type: Resource
database: Gene3D
comment: Tubulin/FtsZ, C-terminal domain
signature sequence match: Gene3D 3.30.1330.20 match 1

http://purl.uniprot.org/gene3d/3.40.50.1440
type: Resource
database: Gene3D
comment: Tubulin/FtsZ, GTPase domain
signature sequence match: Gene3D 3.40.50.1440 match 1

IPR002453
type: Resource
database: InterPro
comment: Beta_tubulin

IPR008280
type: Resource
database: InterPro
comment: Tub_FtsZ_C

IPR000217
type: Resource
database: InterPro
comment: Tubulin

IPR037103
type: Resource
database: InterPro
comment: Tubulin/FtsZ-like_C

IPR018316
type: Resource
database: InterPro
comment: Tubulin/FtsZ_2-layer-sand-dom

IPR036525
type: Resource
database: InterPro
comment: Tubulin/FtsZ_GTPase_sf

IPR023123
type: Resource
database: InterPro
comment: Tubulin_C

IPR017975
type: Resource
database: InterPro
comment: Tubulin_CS

IPR003008
type: Resource
database: InterPro
comment: Tubulin_FtsZ_GTPase

PTHR11588
type: Resource
database: PANTHER
comment: TUBULIN
signature sequence match: PANTHER PTHR11588 match 1

PTHR11588:SF429
type: Resource
database: PANTHER
comment: TUBULIN BETA-1 CHAIN-RELATED
signature sequence match: PANTHER PTHR11588:SF429 match 1

PF00091
type: Resource
database: Pfam
comment: Tubulin
signature sequence match: Pfam PF00091 match 1

PF03953
type: Resource
database: Pfam
comment: Tubulin_C
signature sequence match: Pfam PF03953 match 1

PR01163
type: Resource
database: PRINTS
comment: BETATUBULIN

PR01161
type: Resource
database: PRINTS
comment: TUBULIN

SM00864
type: Resource
database: SMART
comment: Tubulin
signature sequence match: SMART SM00864 match 1

SM00865
type: Resource
database: SMART
comment: Tubulin_C
signature sequence match: SMART SM00865 match 1

SSF55307
type: Resource
database: SUPFAM
comment: Tubulin C-terminal domain-like
signature sequence match: SUPFAM SSF55307 match 1

SSF52490
type: Resource
database: SUPFAM
comment: Tubulin nucleotide-binding domain-like
signature sequence match: SUPFAM SSF52490 match 1

PS00227
type: Resource
database: PROSITE
comment: TUBULIN
signature sequence match: PROSITE PS00227 match 1

SIP4216B33C8D2C6461
type: Structured Name
full name: Tubulin beta chain

btub
type: Gene

SIP0BE48F17A9449180
type: Function Annotation
comment: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

SIP86B2D9341E52AABA
type: Subunit Annotation
comment: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.

SIP2F1562DBB1DC89F5
type: Similarity Annotation
comment: Belongs to the tubulin family.

SIP5C8800CEFFFF1E9F
type: Domain Extent Annotation
comment: Tubulin/FtsZ GTPase
range: 18633781251420974tt1tt135

18633781251420974tt1
type: Position
type: ExactPosition
position: 1
reference: B3SHP3-1

18633781251420974tt135
type: Position
type: ExactPosition
position: 135
reference: B3SHP3-1

SIP58D2F66AECCEDCC2
type: Domain Extent Annotation
comment: Tubulin/FtsZ 2-layer sandwich
range: 18633781251420974tt137tt274

18633781251420974tt137
type: Position
type: ExactPosition
position: 137
reference: B3SHP3-1

18633781251420974tt274
type: Position
type: ExactPosition
position: 274
reference: B3SHP3-1

18633781251420974tt297
type: Position
type: ExactPosition
position: 297
reference: B3SHP3-1

B3SHP3-1
type: Simple Sequence
modified: 2008-09-02
version: 1
fragment: single
mass: 33291
value: AELIDSALDVVRKEAESCDCLQGFQITHSLGGGTGSGMGTLLISKIREEYPDRMMCTYSVVPSPKVSDTVVEPYNATLSVHQLVENADEVFCIDNEALYDICFRTLKLTTPTYGDLNHLVSAVMSGITCCLRFPGQLNADLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAASDPRHGRYLTCAALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSVCDIPPKGLKMATTFIGNSTAIQELFKRVSEQFTGMFRRKAFLHWYTGEGMDEM

A0A125SEA1
type: Protein
reviewed: false
created: 2016-04-13
modified: 2023-02-22
version: 14
mnemonic: A0A125SEA1_9EUKA
citation: http://purl.uniprot.org/citations/26832778
submitted name: SIP31CC8C3D6EB49CB8
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP5F05200B60065629
annotation: SIPAF4F370AEC926409
existence: Predicted Existence
classified with: GO_0005525
classified with: GO_0003924
sequence: A0A125SEA1-1

A0A125SEA1-citation-26832778
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

PTHR47978:SF30
type: Resource
database: PANTHER
comment: RAS-RELATED PROTEIN RAB-33A
signature sequence match: PANTHER PTHR47978:SF30 match 1

SM00176
type: Resource
database: SMART
comment: RAN
signature sequence match: SMART SM00176 match 1

SIP31CC8C3D6EB49CB8
type: Structured Name
full name: RABL2

SIP5F05200B60065629
type: Region Annotation
comment: Disordered
range: -9218582402919283666tt1tt26

-9218582402919283666tt1
type: Position
type: ExactPosition
position: 1
reference: A0A125SEA1-1

-9218582402919283666tt26
type: Position
type: ExactPosition
position: 26
reference: A0A125SEA1-1

SIPAF4F370AEC926409
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: -9218582402919283666tt1tt15

-9218582402919283666tt15
type: Position
type: ExactPosition
position: 15
reference: A0A125SEA1-1

A0A125SEA1-1
type: Simple Sequence
modified: 2016-04-13
version: 1
mass: 23534
value: MSTEAADRTADERPAGAEGEAAAAPGSNEDTVKIILLGDSAVGKSKLVERFLMDDYQPQQLSTYALTLFRHNAEVEGKPIAVDFWDTAGQERFQNLHPSYFHGAHCCVLVFDCTRKVTYTNLSKWYSELQENRYGIPVVVVANKIDVDYRVTRKNFAFASKRNLPFFFVSASDGTNVVQLFTEAIRLAVDCKQNPPEGDFVQDVLDLLGDK

I6LD90
type: Protein
reviewed: false
created: 2012-10-03
modified: 2023-02-22
version: 17
mnemonic: I6LD90_9EUKA
citation: http://purl.uniprot.org/citations/18723395
submitted name: SIP60F41C9A6C653DBD
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIPD4ACD9AF201390C1
annotation: SIP40F92CC6214009AD
annotation: SIP55C80273F2FBE232
existence: Inferred from Homology Existence
sequence: I6LD90-1

I6LD90-citation-18723395
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

cd00012
type: Resource
database: CDD
comment: NBD_sugar-kinase_HSP70_actin
signature sequence match: CDD cd00012 match 1

IPR004000
type: Resource
database: InterPro
comment: Actin

IPR004001
type: Resource
database: InterPro
comment: Actin_CS

IPR043129
type: Resource
database: InterPro
comment: ATPase_NBD

PTHR11937
type: Resource
database: PANTHER
comment: ACTIN
signature sequence match: PANTHER PTHR11937 match 1

PTHR11937:SF387
type: Resource
database: PANTHER
comment: ACTIN
signature sequence match: PANTHER PTHR11937:SF387 match 1

PF00022
type: Resource
database: Pfam
comment: Actin
signature sequence match: Pfam PF00022 match 1

PR00190
type: Resource
database: PRINTS
comment: ACTIN

SM00268
type: Resource
database: SMART
comment: ACTIN
signature sequence match: SMART SM00268 match 1

SSF53067
type: Resource
database: SUPFAM
comment: Actin-like ATPase domain
signature sequence match: SUPFAM SSF53067 match 1
signature sequence match: SUPFAM SSF53067 match 2

PS00432
type: Resource
database: PROSITE
comment: ACTINS_2
signature sequence match: PROSITE PS00432 match 1

SIP60F41C9A6C653DBD
type: Structured Name
full name: Actin

SIPD4ACD9AF201390C1
type: Similarity Annotation
comment: Belongs to the actin family.

20607374489890862tt1
type: Position
type: ExactPosition
position: 1
reference: I6LD90-1

20607374489890862tt259
type: Position
type: ExactPosition
position: 259
reference: I6LD90-1

I6LD90-1
type: Simple Sequence
modified: 2012-10-03
version: 1
fragment: single
mass: 28777
value: EKMHQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLAFVALDFEAEMATAASSSELEKSYELPDGQVITVGNERFRCPEALFQPSFIGLEHAGIHETTYNSIMKCDVDIRKDLYCNVVLSGGTTMYAGIADRMQKELTALAPSSMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPFTVNASRP

D9YM14
type: Protein
reviewed: false
created: 2010-10-05
modified: 2023-02-22
version: 40
mnemonic: D9YM14_9EUKA
citation: SIP1DFEE87303D2B3E1
citation: http://purl.uniprot.org/citations/20656852
submitted name: SIPEB86C9708F6217FA
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIPD844BF088A63C849
annotation: SIPDDE9900AABED7C35
annotation: SIPDF5F1CE83956E8BC
annotation: SIP68B3054D791EB0A6
annotation: SIPC9EC122A11891922
annotation: SIPAD0196D1F14A89ED
annotation: SIP369DD91BD707EFD3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0051082
sequence: D9YM14-1

SIP1DFEE87303D2B3E1
type: Submission Citation
author: Wegener Parfrey L.
author: Grant J.R.
author: Tekle Y.I.
author: Lasek-Nesselquist E.
author: Morrison H.G.
author: Sogin M.L.
author: Patterson D.J.
author: Katz L.A.
date: 2009-07
submitted to: EMBL/GenBank/DDBJ

D9YM14-citation-SIP1DFEE87303D2B3E1
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

D9YM14-citation-20656852
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd16927
type: Resource
database: CDD
comment: HATPase_Hsp90-like
signature sequence match: CDD cd16927 match 1

http://purl.uniprot.org/gene3d/3.30.565.10
type: Resource
database: Gene3D
comment: Histidine kinase-like ATPase, C-terminal domain
signature sequence match: Gene3D 3.30.565.10 match 1

IPR003594
type: Resource
database: InterPro
comment: HATPase_C

IPR036890
type: Resource
database: InterPro
comment: HATPase_C_sf

IPR001404
type: Resource
database: InterPro
comment: Hsp90_fam

IPR020575
type: Resource
database: InterPro
comment: Hsp90_N

IPR020568
type: Resource
database: InterPro
comment: Ribosomal_S5_D2-typ_fold

PTHR11528:SF34
type: Resource
database: PANTHER
comment: HEAT SHOCK PROTEIN 83
signature sequence match: PANTHER PTHR11528:SF34 match 1

PTHR11528
type: Resource
database: PANTHER
comment: HEAT SHOCK PROTEIN 90 FAMILY MEMBER
signature sequence match: PANTHER PTHR11528 match 1

PF02518
type: Resource
database: Pfam
comment: HATPase_c
signature sequence match: Pfam PF02518 match 1

PF00183
type: Resource
database: Pfam
comment: HSP90
signature sequence match: Pfam PF00183 match 1

PR00775
type: Resource
database: PRINTS
comment: HEATSHOCK90

SM00387
type: Resource
database: SMART
comment: HATPase_c
signature sequence match: SMART SM00387 match 1

SSF55874
type: Resource
database: SUPFAM
comment: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
signature sequence match: SUPFAM SSF55874 match 1

SSF54211
type: Resource
database: SUPFAM
comment: Ribosomal protein S5 domain 2-like
signature sequence match: SUPFAM SSF54211 match 1

SIPEB86C9708F6217FA
type: Structured Name
full name: HSP90

SIPD844BF088A63C849
type: Similarity Annotation
comment: Belongs to the heat shock protein 90 family.

SIPDDE9900AABED7C35
type: Domain Extent Annotation
comment: Histidine kinase/HSP90-like ATPase
range: 19203354126267438tt2tt156

19203354126267438tt2
type: Position
type: ExactPosition
position: 2
reference: D9YM14-1

19203354126267438tt156
type: Position
type: ExactPosition
position: 156
reference: D9YM14-1

SIPDF5F1CE83956E8BC
type: Region Annotation
comment: Disordered
range: 19203354126267438tt189tt224

19203354126267438tt189
type: Position
type: ExactPosition
position: 189
reference: D9YM14-1

19203354126267438tt224
type: Position
type: ExactPosition
position: 224
reference: D9YM14-1

SIP68B3054D791EB0A6
type: Compositional Bias Annotation
comment: Acidic residues
range: 19203354126267438tt191tt205

19203354126267438tt191
type: Position
type: ExactPosition
position: 191
reference: D9YM14-1

19203354126267438tt205
type: Position
type: ExactPosition
position: 205
reference: D9YM14-1

SIPC9EC122A11891922
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 19203354126267438tt206tt224

19203354126267438tt206
type: Position
type: ExactPosition
position: 206
reference: D9YM14-1

19203354126267438tt1
type: Position
type: ExactPosition
position: 1
reference: D9YM14-1

19203354126267438tt343
type: Position
type: ExactPosition
position: 343
reference: D9YM14-1

D9YM14-1
type: Simple Sequence
modified: 2010-10-05
version: 1
fragment: single
mass: 38847
value: SNKDIAVRELISNASBALDKIRYESLTDKAALETAPELKVDVIPDKESNTLTIQDTGIGMTKADLINNLGTIARSGTKAFMEAISAGADVSMIGQFGVGFYSAYLIADKVTVVTKNNADDQYIWESSAGGSFTVTKDEGESIGRGTKIILHLKEDQEQFGTEAHIKQIIQRHSIFLAFPINLWVEKTEEKEVTDDEAEEEKADEELPEGDKPKIEEVDEDEEKKTKKTKKVKETHHEFELQNKVKPLWTRNPDEVTTEEYATFYKSLSNDWEEPLATKHFSVEGQLEFRSVLFVPKRAPFDMFEPKKKANNIKLYVRRVFIMDNCEELIPEWLGFVKGIVDSE

B3SHP2
type: Protein
reviewed: false
created: 2008-09-02
modified: 2023-02-22
version: 59
mnemonic: B3SHP2_9EUKA
citation: http://purl.uniprot.org/citations/18205932
recommended name: SIP5C9FF6B2788E480E
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP8F6CB11869FFD8B9
annotation: SIP4795C1F666FDE908
annotation: SIPE97CD7F4786E09A4
annotation: SIP28A01A18ACB78080
annotation: SIP1E8340613C5FB2B8
annotation: SIPD74A8819BA1D271F
annotation: SIP107D08E4ADDE7814
annotation: SIP720FF771A28C3698
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/493
classified with: GO_0005874
classified with: GO_0005525
classified with: GO_0016787
classified with: GO_0005200
classified with: GO_0007017
sequence: B3SHP2-1

B3SHP2-citation-18205932
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

cd02186
type: Resource
database: CDD
comment: alpha_tubulin
signature sequence match: CDD cd02186 match 1

IPR002452
type: Resource
database: InterPro
comment: Alpha_tubulin

PTHR11588:SF239
type: Resource
database: PANTHER
comment: TUBULIN ALPHA-4 CHAIN
signature sequence match: PANTHER PTHR11588:SF239 match 1

PR01162
type: Resource
database: PRINTS
comment: ALPHATUBULIN

SIP5C9FF6B2788E480E
type: Structured Name
full name: Tubulin alpha chain

atub
type: Gene

SIP8F6CB11869FFD8B9
type: Function Annotation
comment: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

SIPE97CD7F4786E09A4
type: Subunit Annotation
comment: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.

SIP28A01A18ACB78080
type: Similarity Annotation
comment: Belongs to the tubulin family.

SIP1E8340613C5FB2B8
type: Domain Extent Annotation
comment: Tubulin/FtsZ GTPase
range: 18633781251420718tt20tt217

18633781251420718tt20
type: Position
type: ExactPosition
position: 20
reference: B3SHP2-1

18633781251420718tt217
type: Position
type: ExactPosition
position: 217
reference: B3SHP2-1

SIPD74A8819BA1D271F
type: Domain Extent Annotation
comment: Tubulin/FtsZ 2-layer sandwich
range: 18633781251420718tt219tt364

18633781251420718tt219
type: Position
type: ExactPosition
position: 219
reference: B3SHP2-1

18633781251420718tt364
type: Position
type: ExactPosition
position: 364
reference: B3SHP2-1

18633781251420718tt1
type: Position
type: ExactPosition
position: 1
reference: B3SHP2-1

18633781251420718tt373
type: Position
type: ExactPosition
position: 373
reference: B3SHP2-1

B3SHP2-1
type: Simple Sequence
modified: 2008-09-02
version: 1
fragment: single
mass: 41372
value: IQPDGQMPSDKTVGYGDDAFNTFFSETGAGKHVPRAVYVDLEPTAVDEVRTGTYRQLFHPEQLISGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHALGGGTGAGLGSLLLERLSVDYGKKSKLDFVVYPCPQVSTAVVEPYNCILSAHSMLEHTDCSFLVDNEALYDICRRNLDVERPTYTNLNRLIAQLISSMTASLRFDGALNVDLTEFQTNLVPYPRIHFPLCSYAPVISAEKAYHEQLSVAEITNTVFEPASSMVKCDPRHGKYMACCVLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRSILMISNTTAIAEVWSRLDHKFDLMYAKR

B3SHQ3
type: Protein
reviewed: false
created: 2008-09-02
modified: 2023-02-22
version: 26
mnemonic: B3SHQ3_9EUKA
citation: http://purl.uniprot.org/citations/18205932
submitted name: SIP60F41C9A6C653DBD
organism: http://purl.uniprot.org/taxonomy/554453
annotation: SIP2FED4A4785C4530E
annotation: SIPD92FC34625243535
annotation: SIP5AEFBE00B1479E0B
existence: Inferred from Homology Existence
sequence: B3SHQ3-1

B3SHQ3-citation-18205932
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

ATCC 50267
type: Strain

IPR020902
type: Resource
database: InterPro
comment: Actin/actin-like_CS

PS01132
type: Resource
database: PROSITE
comment: ACTINS_ACT_LIKE
signature sequence match: PROSITE PS01132 match 1

SIP60F41C9A6C653DBD
type: Structured Name
full name: Actin

SIP2FED4A4785C4530E
type: Similarity Annotation
comment: Belongs to the actin family.

18633781251486510tt1
type: Position
type: ExactPosition
position: 1
reference: B3SHQ3-1

18633781251486510tt265
type: Position
type: ExactPosition
position: 265
reference: B3SHQ3-1

B3SHQ3-1
type: Simple Sequence
modified: 2008-09-02
version: 1
fragment: single
mass: 29474
value: WHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLAFVALDFEAEMATAASSSELEKSYELPDGQVITVGNERFRCPEALFQPSFIGLEHAGIHETTYNSIMKCDVDIRKDLYCNVVLSGGTTMYAGIADRMQKELTALAPSSMKIKIIAPPERKYSVWIGGSILASLS

A0A060MZP8
type: Protein
reviewed: false
created: 2014-09-03
modified: 2023-02-22
version: 23
mnemonic: A0A060MZP8_9EUKA
citation: SIP8957282E9CE978E6
submitted name: SIP19F6306D51C4AC72
organism: http://purl.uniprot.org/taxonomy/1246791
annotation: SIPA72E88A47CE611C4
annotation: SIP56D85F8E866291A8
existence: Evidence at Transcript Level Existence
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/342
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0003746
sequence: A0A060MZP8-1

…
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

NYK3C
type: Strain

cd03693
type: Resource
database: CDD
comment: EF1_alpha_II
signature sequence match: CDD cd03693 match 1

cd03705
type: Resource
database: CDD
comment: EF1_alpha_III
signature sequence match: CDD cd03705 match 1

http://purl.uniprot.org/gene3d/2.40.30.10
type: Resource
database: Gene3D
comment: Translation factors
signature sequence match: Gene3D 2.40.30.10 match 1
signature sequence match: Gene3D 2.40.30.10 match 2

IPR004161
type: Resource
database: InterPro
comment: EFTu-like_2

IPR009000
type: Resource
database: InterPro
comment: Transl_B-barrel_sf

IPR009001
type: Resource
database: InterPro
comment: Transl_elong_EF1A/Init_IF2_C

IPR004160
type: Resource
database: InterPro
comment: Transl_elong_EFTu/EF1A_C

PF03144
type: Resource
database: Pfam
comment: GTP_EFTU_D2
signature sequence match: Pfam PF03144 match 1

PF03143
type: Resource
database: Pfam
comment: GTP_EFTU_D3
signature sequence match: Pfam PF03143 match 1

SSF50465
type: Resource
database: SUPFAM
comment: EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
signature sequence match: SUPFAM SSF50465 match 1

SSF50447
type: Resource
database: SUPFAM
comment: Translation proteins
signature sequence match: SUPFAM SSF50447 match 1

SIP19F6306D51C4AC72
type: Structured Name
full name: Elongation factor-like protein

EFL
type: Gene

SIPA72E88A47CE611C4
type: Similarity Annotation
comment: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

SIP56D85F8E866291A8
type: Domain Extent Annotation
comment: Tr-type G
range: -9218586547943104466tt5tt253

-9218586547943104466tt5
type: Position
type: ExactPosition
position: 5
reference: A0A060MZP8-1

-9218586547943104466tt253
type: Position
type: ExactPosition
position: 253
reference: A0A060MZP8-1

A0A060MZP8-1
type: Simple Sequence
modified: 2014-09-03
version: 1
mass: 51413
value: MSEGKEHLSIVICGHVDSGKSTTTGRLLFELGGIPEREMEKLKQEAERLGKASFAFAFYMDRQKDERERGVTIACTTKEFFTDKWHYTIIDAPGHRDFIKNMISGAAQADVALLMVPADGNFTTAIQKGDHKAGDIQGQTRQHARLLNLLGVKQLLVGVNKMDEKTSAGYKEARYNEIADEMRDMLAKVGWKKDFIKESVPVLPISGWMGDNLLTKSENMAWWKGQKVKSMSGREVEVNTLKDALNDLIELPSRKADSPMRTPISGIYKIKGVGDVLAGRVEQGTVEPNTDVIFLPTHTSANACAGKVFTVEMHHKRVDKAQTGDNVGMNIKGLDKQNMPHVGDVMIYKSDDTLKHVKNFTAQVQTLDIPGELKAGYSPIGFVRCGRSACRIKELNWKIGKETGRKKLESPHSLKSNEAAEIVFEPIQPLIVDTFANCEGLSRIAFLDGNTAVMLGKVVKVEHK