Comparative analysis of mitochondrial genomes of the ancient jakobid protists.
NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L
Cytochrome c oxidase subunit II-like, transmembrane region
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Belongs to the cytochrome c oxidase subunit 2 family.
Cytochrome oxidase subunit II transmembrane region profile
Cytochrome oxidase subunit II copper A binding
NADH:ubiquinone/plastoquinone oxidoreductase, chain 3
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
Belongs to the complex I subunit 3 family.
28S RIBOSOMAL PROTEIN S12, MITOCHONDRIAL
Belongs to the universal ribosomal protein uS12 family.
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
Cytochrome c-type biogenesis protein CcmF C-terminal
Fumarate reductase/succinate dehydrogenase, transmembrane subunit
SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT
SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL
Fumarate reductase respiratory complex transmembrane subunits
The heme is bound between the two transmembrane subunits.
ligand shared with second transmembrane subunit
NADH:ubiquinone oxidoreductase, 30kDa subunit
NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL
NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3
Belongs to the complex I 30 kDa subunit family.
NADH:ubiquinone oxidoreductase 30kDa subunit
39S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL
Belongs to the bacterial ribosomal protein bL20 family.
Belongs to the universal ribosomal protein uS8 family.
Prokaryotic type KH domain (KH-domain type II)
Belongs to the universal ribosomal protein uS3 family.
Belongs to the bacterial ribosomal protein bL19 family.
30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR
Belongs to the universal ribosomal protein uS2 family.
39S RIBOSOMAL PROTEIN L16, MITOCHONDRIAL
Belongs to the universal ribosomal protein uL16 family.
Cytochrome c oxidase-like, subunit I domain
Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
Belongs to the heme-copper respiratory oxidase family.
SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC
SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC, CHLOROPLASTIC-RELATED
Sec-independent protein translocase component TatC
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
37S RIBOSOMAL PROTEIN S19, MITOCHONDRIAL
Belongs to the universal ribosomal protein uS19 family.
40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11
Belongs to the universal ribosomal protein uS11 family.
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cytochrome b/b6 N-terminal region profile
Cytochrome b/b6 C-terminal region profile
28S RIBOSOMAL PROTEIN S14, MITOCHONDRIAL
Glucocorticoid receptor-like (DNA-binding domain)
Belongs to the universal ribosomal protein uS14 family.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Belongs to the complex I subunit 5 family.
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
54S RIBOSOMAL PROTEIN L38, MITOCHONDRIAL
Belongs to the universal ribosomal protein uL14 family.
Belongs to the universal ribosomal protein uL2 family.
Belongs to the universal ribosomal protein uS7 family.
ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL
F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ
Belongs to the complex I subunit 6 family.
37S RIBOSOMAL PROTEIN NAM9, MITOCHONDRIAL
Belongs to the universal ribosomal protein uS4 family.
Belongs to the complex I subunit 4 family.
Belongs to the universal ribosomal protein uL6 family.
Histidine kinase-like ATPase, C-terminal domain
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
Belongs to the heat shock protein 90 family.
Elongation Factor G (Translational Gtpase), domain 3
P-loop containing nucleotide triphosphate hydrolases
EUKARYOTIC TRANSLATION ELONGATION FACTOR 2
P-loop containing nucleoside triphosphate hydrolases
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Ribosomal protein L11/L12, N-terminal domain
39S RIBOSOMAL PROTEIN L11, MITOCHONDRIAL
Belongs to the universal ribosomal protein uL11 family.
Belongs to the universal ribosomal protein uL5 family.
30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18
37S RIBOSOMAL PROTEIN SWS2, MITOCHONDRIAL
Belongs to the universal ribosomal protein uS13 family.
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
Belongs to the complex I subunit 1 family.
Cytochrome c oxidase, subunit III, four-helix bundle
Belongs to the cytochrome c oxidase subunit 3 family.
Heme-copper oxidase subunit III family profile
Medium-chain alcohol dehydrogenases, catalytic domain
TCP-1-like chaperonin intermediate domain
YVTN repeat-like/Quinoprotein amine dehydrogenase
Belongs to the WD repeat peroxin-7 family.
CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF
Ribosome maturation protein SBDS, N-terminal domain
SBDS protein C-terminal domain, subdomain 1
RESTRICTION OF TELOMERE CAPPING PROTEIN 3
Hypothetical protein AF0491, middle domain
Shwachman-Bodian-Diamond protein-like protein
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Formate/glycerate dehydrogenase catalytic domain-like
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Belongs to the bacterial ribosomal protein bL36 family.
An ancient spliceosomal intron in the Rpl7A gene.
Belongs to the eukaryotic ribosomal protein eL8 family.
DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
beta and beta-prime subunits of DNA dependent RNA-polymerase
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Belongs to the RNA polymerase beta' chain family.
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
RIBOSOMAL PROTEIN S11, MITOCHONDRIAL-RELATED
Bacterial type II secretion system protein E
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Spo11/DNA topoisomerase VI subunit A N-terminal
Belongs to the enoyl-CoA hydratase/isomerase family.
50S ribosomal protein L31, chloroplastic
Ribosomal protein L11, C-terminal domain
TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED
Heat shock protein 90, C-terminal domain
Type II secretion system protein GspG C-terminal
HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED
Heat shock protein 70kD (HSP70), C-terminal subdomain
Heat shock protein 70kD (HSP70), peptide-binding domain
Belongs to the heat shock protein 70 family.
NADH:ubiquinone oxidoreductase chain 4 N-terminal
TYPE II SECRETION SYSTEM PROTEIN F-RELATED
39S RIBOSOMAL PROTEIN L19, MITOCHONDRIAL
Lacks conserved residue(s) required for the propagation of feature annotation.
RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY
28S RIBOSOMAL PROTEIN S11, MITOCHONDRIAL
SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC-RELATED
Belongs to the ParA family. MinD subfamily.
Cell division topological specificity factor MinE
Cell division protein MinE topological specificity domain
Cell-division inhibitor MinC, C-terminal domain
Septum formation inhibitor MinC C-terminal