Q6MGX6
type: Protein
reviewed: true
created: 2006-12-12
modified: 2023-09-13
version: 85
mnemonic: 3MGH_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP5A237E3C5A0F7C9A
enzyme: http://purl.uniprot.org/enzyme/3.2.2.-
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPCA3338BE79B8DAE6
annotation: PRO_0000264999
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003905
classified with: GO_0003677
classified with: GO_0006284
sequence: MILPQEFYFEDTTLVAQSLLGKVLNIRTDSGIQKARIIETEAYLGIEDPACHTFEDRRTERTKSMYLDGGHSYVYMIYGMYFCLNFVTRTHQHPEAVLIRAVEPLPAQENLRKKDLKTNGPGKLCKYYGITRKHDGLKLWKKSSDLYVTDEDFKVSKKQIIPTARVGVDYAGEAAKWPLRFYLRDHLFVSKK
proteome: Chromosome

Q6MGX6-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG2094
type: Resource
database: eggNOG
comment: Bacteria

cd00540
type: Resource
database: CDD
comment: AAG
signature sequence match: CDD cd00540 match 1

http://purl.uniprot.org/gene3d/3.10.300.10
type: Resource
database: Gene3D
comment: Methylpurine-DNA glycosylase (MPG)
signature sequence match: Gene3D 3.10.300.10 match 1

MF_00527
type: Resource
database: HAMAP
comment: 3MGH
signature sequence match: HAMAP MF 00527 match 1

IPR011034
type: Resource
database: InterPro
comment: Formyl_transferase-like_C_sf

IPR003180
type: Resource
database: InterPro
comment: MPG

IPR036995
type: Resource
database: InterPro
comment: MPG_sf

TIGR00567
type: Resource
database: NCBIfam
comment: 3mg
signature sequence match: NCBIfam TIGR00567 match 1

PTHR10429
type: Resource
database: PANTHER
comment: DNA-3-METHYLADENINE GLYCOSYLASE
signature sequence match: PANTHER PTHR10429 match 1

PTHR10429:SF0
type: Resource
database: PANTHER
comment: DNA-3-METHYLADENINE GLYCOSYLASE
signature sequence match: PANTHER PTHR10429:SF0 match 1

PF02245
type: Resource
database: Pfam
comment: Pur_DNA_glyco
signature sequence match: Pfam PF02245 match 1

SSF50486
type: Resource
database: SUPFAM
comment: FMT C-terminal domain-like
signature sequence match: SUPFAM SSF50486 match 1

SIP5A237E3C5A0F7C9A
type: Structured Name
full name: Putative 3-methyladenine DNA glycosylase
ec name: 3.2.2.-

http://purl.uniprot.org/uniprot/Q6MGX6#gene-MD54CA9175D70B2E7A4C499B8CE6A930697
type: Gene
locus name: Bd3793

SIPCA3338BE79B8DAE6
type: Similarity Annotation
comment: Belongs to the DNA glycosylase MPG family.

PRO_0000264999
type: Chain Annotation
comment: Putative 3-methyladenine DNA glycosylase
mass: 22260
range: 22859178650908206tt1tt192

22859178650908206tt1
type: Position
type: ExactPosition
position: 1
reference: MILPQEFYFEDTTLVAQSLLGKVLNIRTDSGIQKARIIETEAYLGIEDPACHTFEDRRTERTKSMYLDGGHSYVYMIYGMYFCLNFVTRTHQHPEAVLIRAVEPLPAQENLRKKDLKTNGPGKLCKYYGITRKHDGLKLWKKSSDLYVTDEDFKVSKKQIIPTARVGVDYAGEAAKWPLRFYLRDHLFVSKK

22859178650908206tt192
type: Position
type: ExactPosition
position: 192
reference: MILPQEFYFEDTTLVAQSLLGKVLNIRTDSGIQKARIIETEAYLGIEDPACHTFEDRRTERTKSMYLDGGHSYVYMIYGMYFCLNFVTRTHQHPEAVLIRAVEPLPAQENLRKKDLKTNGPGKLCKYYGITRKHDGLKLWKKSSDLYVTDEDFKVSKKQIIPTARVGVDYAGEAAKWPLRFYLRDHLFVSKK

MILPQEFYFEDTTLVAQSLLGKVLNIRTDSGIQKARIIETEAYLGIEDPACHTFEDRRTERTKSMYLDGGHSYVYMIYGMYFCLNFVTRTHQHPEAVLIRAVEPLPAQENLRKKDLKTNGPGKLCKYYGITRKHDGLKLWKKSSDLYVTDEDFKVSKKQIIPTARVGVDYAGEAAKWPLRFYLRDHLFVSKK
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 22260

http://purl.uniprot.org/uniprot/Q6MGX6#attribution-9DC027CD38BBC94810E46F630C5D32ED
manual: true
evidence: ECO_0000255
source: MF_00527

Q6MLJ8
type: Protein
reviewed: true
created: 2005-03-01
modified: 2023-09-13
version: 102
mnemonic: ACP_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPF018D8BE7E205B4F
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP8E5D01DCA255BA73
annotation: SIP378CCC5301795E90
annotation: SIPC033EEA28EAC756F
annotation: SIP0BC7E89CFD2BA510
annotation: SIP3DE0725233F75572
annotation: PRO_0000180108
annotation: SIP8BA489D64523AEA6
annotation: SIP445B3C621166C187
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/275
classified with: http://purl.uniprot.org/keywords/596
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0000036
sequence: MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA
proteome: Chromosome

Q6MLJ8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0236
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.1200.10
type: Resource
database: Gene3D
comment: ACP-like
signature sequence match: Gene3D 1.10.1200.10 match 1

MF_01217
type: Resource
database: HAMAP
comment: Acyl_carrier
signature sequence match: HAMAP MF 01217 match 1

IPR036736
type: Resource
database: InterPro
comment: ACP-like_sf

IPR003231
type: Resource
database: InterPro
comment: Acyl_carrier

IPR009081
type: Resource
database: InterPro
comment: PP-bd_ACP

IPR006162
type: Resource
database: InterPro
comment: Ppantetheine_attach_site

TIGR00517
type: Resource
database: NCBIfam
comment: acyl_carrier
signature sequence match: NCBIfam TIGR00517 match 1

PTHR20863
type: Resource
database: PANTHER
comment: ACYL CARRIER PROTEIN
signature sequence match: PANTHER PTHR20863 match 1

PTHR20863:SF28
type: Resource
database: PANTHER
comment: ACYL CARRIER PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR20863:SF28 match 1

PF00550
type: Resource
database: Pfam
comment: PP-binding
signature sequence match: Pfam PF00550 match 1

SSF47336
type: Resource
database: SUPFAM
comment: ACP-like
signature sequence match: SUPFAM SSF47336 match 1

PS50075
type: Resource
database: PROSITE
comment: CARRIER
signature sequence match: PROSITE PS50075 match 1

PS00012
type: Resource
database: PROSITE
comment: PHOSPHOPANTETHEINE
signature sequence match: PROSITE PS00012 match 1

SIPF018D8BE7E205B4F
type: Structured Name
full name: Acyl carrier protein
short name: ACP

acpP
type: Gene
locus name: Bd2011

SIP8E5D01DCA255BA73
type: Function Annotation
comment: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

SIP0BC7E89CFD2BA510
type: PTM Annotation
comment: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.

SIP3DE0725233F75572
type: Similarity Annotation
comment: Belongs to the acyl carrier protein (ACP) family.

PRO_0000180108
type: Chain Annotation
comment: Acyl carrier protein
mass: 8631
range: 22859178733877294tt1tt78

22859178733877294tt1
type: Position
type: ExactPosition
position: 1
reference: MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA

22859178733877294tt78
type: Position
type: ExactPosition
position: 78
reference: MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA

SIP8BA489D64523AEA6
type: Domain Extent Annotation
comment: Carrier
range: 22859178733877294tt1tt76

22859178733877294tt76
type: Position
type: ExactPosition
position: 76
reference: MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA

SIP445B3C621166C187
type: Modified Residue Annotation
comment: O-(pantetheine 4'-phosphoryl)serine
range: 22859178733877294tt36tt36

22859178733877294tt36
type: Position
type: ExactPosition
position: 36
reference: MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA

MAIHPKVKDIIVEQLGVDPDKVKAEASFIDDLGADSLDIVELVMAMEEEFDLEIPDEDAEKLKTVQDVASYLEKKGKA
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 8631

http://purl.uniprot.org/uniprot/Q6MLJ8#attribution-EBFCF1D44A6B78477DFBD33475E43FB0
manual: true
evidence: ECO_0000255
source: MF_01217

http://purl.uniprot.org/uniprot/Q6MLJ8#attribution-D13C97E04C041CF3567C01508AE538D1
manual: true
evidence: ECO_0000255
source: PRU00258

Q6MNF1
type: Protein
reviewed: true
created: 2008-02-05
modified: 2023-09-13
version: 100
mnemonic: ACSA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPEE7A9725AAD3935C
alternative name: SIPB1DE999BD73CE87E
alternative name: SIP47EF8A93DA3133C1
enzyme: http://purl.uniprot.org/enzyme/6.2.1.1
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP05BF68F5B3C7E8C4
annotation: SIP3F17D8C219D9E7E7
annotation: SIP29553EEAA1DF4CB0
annotation: SIPD4651B2887F020BB
annotation: SIPB3E0E076FE0E0486
annotation: PRO_1000065272
annotation: SIP7D87E5C1ABAAD939
annotation: SIP6DF150178A5E56D0
annotation: SIPE3A726FE6A0F9665
annotation: SIP096DBAFB3D7836CB
annotation: SIP1B1DE9660218190F
annotation: SIP4D06F002F8EED873
annotation: SIP1F42EA4C2DC4DF43
annotation: SIPEF58432E51F54D35
annotation: SIP6ACA53C75B0895C1
annotation: SIPFD064B8F3F962A8E
annotation: SIP74B69789A3E70E4B
annotation: SIP35F380B5EEE53998
annotation: SIPDAE4ABD3E350259F
annotation: SIP78BA55D9AF4118D8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/7
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003987
classified with: GO_0016208
classified with: GO_0005524
classified with: GO_0046872
classified with: GO_0019427
sequence: Q6MNF1-1
proteome: Chromosome

Q6MNF1-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0365
type: Resource
database: eggNOG
comment: Bacteria

cd05966
type: Resource
database: CDD
comment: ACS
signature sequence match: CDD cd05966 match 1

http://purl.uniprot.org/gene3d/3.40.50.12780
type: Resource
database: Gene3D
comment: N-terminal domain of ligase-like
signature sequence match: Gene3D 3.40.50.12780 match 1

MF_01123
type: Resource
database: HAMAP
comment: Ac_CoA_synth
signature sequence match: HAMAP MF 01123 match 1

IPR011904
type: Resource
database: InterPro
comment: Ac_CoA_lig

IPR032387
type: Resource
database: InterPro
comment: ACAS_N

IPR025110
type: Resource
database: InterPro
comment: AMP-bd_C

IPR045851
type: Resource
database: InterPro
comment: AMP-bd_C_sf

IPR020845
type: Resource
database: InterPro
comment: AMP-binding_CS

IPR000873
type: Resource
database: InterPro
comment: AMP-dep_Synth/Lig_com

IPR042099
type: Resource
database: InterPro
comment: ANL_N_sf

TIGR02188
type: Resource
database: NCBIfam
comment: Ac_CoA_lig_AcsA
signature sequence match: NCBIfam TIGR02188 match 1

PTHR24095
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A SYNTHETASE
signature sequence match: PANTHER PTHR24095 match 1

PTHR24095:SF14
type: Resource
database: PANTHER
comment: ACETYL-COENZYME A SYNTHETASE 1
signature sequence match: PANTHER PTHR24095:SF14 match 1

PF16177
type: Resource
database: Pfam
comment: ACAS_N
signature sequence match: Pfam PF16177 match 1

PF00501
type: Resource
database: Pfam
comment: AMP-binding
signature sequence match: Pfam PF00501 match 1

PF13193
type: Resource
database: Pfam
comment: AMP-binding_C
signature sequence match: Pfam PF13193 match 1

SSF56801
type: Resource
database: SUPFAM
comment: Acetyl-CoA synthetase-like
signature sequence match: SUPFAM SSF56801 match 1

PS00455
type: Resource
database: PROSITE
comment: AMP_BINDING
signature sequence match: PROSITE PS00455 match 1

SIPEE7A9725AAD3935C
type: Structured Name
full name: Acetyl-coenzyme A synthetase
short name: AcCoA synthetase
short name: Acs
ec name: 6.2.1.1

SIPB1DE999BD73CE87E
type: Structured Name
full name: Acetate--CoA ligase

SIP47EF8A93DA3133C1
type: Structured Name
full name: Acyl-activating enzyme

acsA
type: Gene
locus name: Bd1306

SIP05BF68F5B3C7E8C4
type: Function Annotation
comment: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

SIPD4651B2887F020BB
type: PTM Annotation
comment: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.

SIPB3E0E076FE0E0486
type: Similarity Annotation
comment: Belongs to the ATP-dependent AMP-binding enzyme family.

PRO_1000065272
type: Chain Annotation
comment: Acetyl-coenzyme A synthetase
mass: 72415
range: 22859178767167790tt1tt645

22859178767167790tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MNF1-1

22859178767167790tt645
type: Position
type: ExactPosition
position: 645
reference: Q6MNF1-1

22859178767167790tt190
type: Position
type: ExactPosition
position: 190
reference: Q6MNF1-1

22859178767167790tt193
type: Position
type: ExactPosition
position: 193
reference: Q6MNF1-1

22859178767167790tt308
type: Position
type: ExactPosition
position: 308
reference: Q6MNF1-1

22859178767167790tt332
type: Position
type: ExactPosition
position: 332
reference: Q6MNF1-1

22859178767167790tt384
type: Position
type: ExactPosition
position: 384
reference: Q6MNF1-1

22859178767167790tt386
type: Position
type: ExactPosition
position: 386
reference: Q6MNF1-1

22859178767167790tt408
type: Position
type: ExactPosition
position: 408
reference: Q6MNF1-1

22859178767167790tt413
type: Position
type: ExactPosition
position: 413
reference: Q6MNF1-1

22859178767167790tt497
type: Position
type: ExactPosition
position: 497
reference: Q6MNF1-1

22859178767167790tt512
type: Position
type: ExactPosition
position: 512
reference: Q6MNF1-1

22859178767167790tt520
type: Position
type: ExactPosition
position: 520
reference: Q6MNF1-1

22859178767167790tt523
type: Position
type: ExactPosition
position: 523
reference: Q6MNF1-1

22859178767167790tt534
type: Position
type: ExactPosition
position: 534
reference: Q6MNF1-1

22859178767167790tt536
type: Position
type: ExactPosition
position: 536
reference: Q6MNF1-1

22859178767167790tt539
type: Position
type: ExactPosition
position: 539
reference: Q6MNF1-1

22859178767167790tt581
type: Position
type: ExactPosition
position: 581
reference: Q6MNF1-1

SIP78BA55D9AF4118D8
type: Modified Residue Annotation
comment: N6-acetyllysine
range: 22859178767167790tt606tt606

22859178767167790tt606
type: Position
type: ExactPosition
position: 606
reference: Q6MNF1-1

Q6MNF1-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 72415
value: MHKELYPVNSEVAKKAWIDEAKYKAMYERSIQDNEAFWAEQAERLDWIKKWDKVKEVSFKKPVSIKWYLGGKMNVSYNCVDRHLKTRGDKTALLWEADNPSTPSRKITYKELHLEVCRFANVLKKMGVKKGDVVTIYMPMIPDTAVAMLACARIGAVHSVVFAGFSPDSISDRILDGQCRFVITGDAGFRGSKVVALKENIDKALVKTPDVQKVLVVKYAGTTVDMKPGRDLWYHEEVKTVSDQCEPEPMDAEDPLFILYTSGSTGKPKGVMHTTGGYLVYASMTHQYVFDYHEDDIYWCSADVGWVTGHSYIVYGPLANGATSLFFEGVPNYPTPSRFWEVVDKHKVTIFYTSPTAIRSLMREGDAAVKTTSRKTLRLLGSVGEPINPEAWAWYHDVVGEGRCPVVDTWWQTETGGILITPLPGAIAQKPGSATLPFFGVQPKLLTNEGQEIHGPGEGVLVIADSWPGQMRTVYRNHERFEDTYFSNYPGYYFTGDGCRRDQDGYYWITGRVDDVINVSGHRLGTAEIESALVAHHKVAEAAVVGYPHDIKGQGIYAFVTLKSGETASEELRKELIQTVRKEIGPIATPDLIQWAPRLPKTRSGKIMRRILRKIAENHPDQLGDTTTLSEPAVVQELVDNRMNR

http://purl.uniprot.org/uniprot/Q6MNF1#attribution-392F9CA02341F2C9C90C52E35C293B01
manual: true
evidence: ECO_0000255
source: MF_01123

Q6MJY0
type: Protein
reviewed: true
created: 2004-08-16
modified: 2023-09-13
version: 100
mnemonic: ADEC_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPE5145F1993188E2E
enzyme: http://purl.uniprot.org/enzyme/3.5.4.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPD23903E54E13118B
annotation: SIP0FDFEE577DA9C9D8
annotation: SIP08CA09E92A62D4BE
annotation: PRO_0000142405
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0000034
classified with: GO_0006146
sequence: Q6MJY0-1
proteome: Chromosome

Q6MJY0-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1001
type: Resource
database: eggNOG
comment: Bacteria

cd01295
type: Resource
database: CDD
comment: AdeC
signature sequence match: CDD cd01295 match 1

http://purl.uniprot.org/gene3d/3.20.20.140
type: Resource
database: Gene3D
comment: Metal-dependent hydrolases
signature sequence match: Gene3D 3.20.20.140 match 1

http://purl.uniprot.org/gene3d/2.30.40.10
type: Resource
database: Gene3D
comment: Urease, subunit C, domain 1
signature sequence match: Gene3D 2.30.40.10 match 1

MF_01518
type: Resource
database: HAMAP
comment: Adenine_deamin
signature sequence match: HAMAP MF 01518 match 1

IPR006679
type: Resource
database: InterPro
comment: Adenine_deam

IPR026912
type: Resource
database: InterPro
comment: Adenine_deam_C

IPR006680
type: Resource
database: InterPro
comment: Amidohydro-rel

IPR011059
type: Resource
database: InterPro
comment: Metal-dep_hydrolase_composite

IPR032466
type: Resource
database: InterPro
comment: Metal_Hydrolase

TIGR01178
type: Resource
database: NCBIfam
comment: ade
signature sequence match: NCBIfam TIGR01178 match 1

PTHR11113:SF2
type: Resource
database: PANTHER
comment: ADENINE DEAMINASE
signature sequence match: PANTHER PTHR11113:SF2 match 1

PTHR11113
type: Resource
database: PANTHER
comment: N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE
signature sequence match: PANTHER PTHR11113 match 1

PF13382
type: Resource
database: Pfam
comment: Adenine_deam_C
signature sequence match: Pfam PF13382 match 1

PF01979
type: Resource
database: Pfam
comment: Amidohydro_1
signature sequence match: Pfam PF01979 match 1

SSF51338
type: Resource
database: SUPFAM
comment: Composite domain of metallo-dependent hydrolases
signature sequence match: SUPFAM SSF51338 match 1

SSF51556
type: Resource
database: SUPFAM
comment: Metallo-dependent hydrolases
signature sequence match: SUPFAM SSF51556 match 1

SIPE5145F1993188E2E
type: Structured Name
full name: Adenine deaminase
short name: Adenase
short name: Adenine aminase
ec name: 3.5.4.2

ade
type: Gene
locus name: Bd2636

SIP08CA09E92A62D4BE
type: Similarity Annotation
comment: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

PRO_0000142405
type: Chain Annotation
comment: Adenine deaminase
mass: 63714
range: 22859178701303854tt1tt586

22859178701303854tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MJY0-1

22859178701303854tt586
type: Position
type: ExactPosition
position: 586
reference: Q6MJY0-1

Q6MJY0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 63714
value: MSLSNKKTQKIASDLLPARLSQARGDGTLDLLITNVQMLDVITGDIYPTCIAIGGEHIVGVGMEYQTQSARRTWNALGAFVTPGFIDGHLHIESSMMSPFEFEKATLPLGTTTAICDPHEITNVLGGRGFSWFLRSSELMHQNLFVQMSSCVPALPGFETTGSDFPLEEMKSFKDHPSVLGLAEMMNFPGVIHADEEVLAKIEAFDDLNMDGHAPLLRGKALNAYLLAGIQNCHETVTLEEGREKLQKGMGLIIREGSVAKNLRTLAPLVNEFSSPQCLLCTDDRNPFEIAHEGHINYLIKELINKHGVAVHVAYRLATYSAARHFGLKRLGLVAPGKKADLVFLKDLKAVDIQEVMIGGKFVSELKLQDSLQEKLQTSQPPLENTMKRSPLTEKELTVNLLPGVYNVIEIVPHEIITQHLTVAFDGQKFAESDVLYMANIERYGKGLPPALGLVKGMGLKSGALASSVAHDSHNIMVIGTNPADMVLAVNTLIKSGGGFAVADQGEIKALVELPIAGLLSLKSAEEIKDGIADLKTAFRSLGVHLDEPFIQMAFLALPVIPTLKLTDRGLVNVTNFSFIPLQVEA

http://purl.uniprot.org/uniprot/Q6MJY0#attribution-991395F568AA9E0C148C4CFE5DC1B91B
manual: true
evidence: ECO_0000255
source: MF_01518

Q6MH10
type: Protein
reviewed: true
created: 2004-12-07
modified: 2023-06-28
version: 99
mnemonic: AMPA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP4C2E197687D5A48E
alternative name: SIP8E066A1821A9A88A
alternative name: SIP2BA06BA51D2DD54D
enzyme: http://purl.uniprot.org/enzyme/3.4.11.1
enzyme: http://purl.uniprot.org/enzyme/3.4.11.10
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP2B7D4553A0C6296E
annotation: SIPE742D9DD2B2A895E
annotation: SIP1A898DCAF662ED39
annotation: SIPADEEE18C01448C6D
annotation: SIP72C81B2FEC34DCC8
annotation: SIPDCF845F52A5AA8F0
annotation: PRO_0000165723
annotation: SIP947B3C22ADF616E5
annotation: SIP1613F74DB8B7EEEC
annotation: SIPD7E56A3298375D3D
annotation: SIP594BFB7117E92A26
annotation: SIP4825996E33E9FF9B
annotation: SIP4AD64AF449393EC8
annotation: SIP17C499E7558B4A60
annotation: SIP19A651E7DF4F88EB
annotation: SIP7846AFAE27C4692E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/31
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0030145
classified with: GO_0070006
classified with: GO_0006508
sequence: Q6MH10-1
proteome: Chromosome

Q6MH10-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0260
type: Resource
database: eggNOG
comment: Bacteria

cd00433
type: Resource
database: CDD
comment: Peptidase_M17
signature sequence match: CDD cd00433 match 1

http://purl.uniprot.org/gene3d/3.40.220.10
type: Resource
database: Gene3D
comment: Leucine Aminopeptidase, subunit E, domain 1
signature sequence match: Gene3D 3.40.220.10 match 1

http://purl.uniprot.org/gene3d/3.40.630.10
type: Resource
database: Gene3D
comment: Zn peptidases
signature sequence match: Gene3D 3.40.630.10 match 1

MF_00181
type: Resource
database: HAMAP
comment: Cytosol_peptidase_M17
signature sequence match: HAMAP MF 00181 match 1

IPR011356
type: Resource
database: InterPro
comment: Leucine_aapep/pepB

IPR043472
type: Resource
database: InterPro
comment: Macro_dom-like

IPR000819
type: Resource
database: InterPro
comment: Peptidase_M17_C

IPR023042
type: Resource
database: InterPro
comment: Peptidase_M17_leu_NH2_pept

IPR008283
type: Resource
database: InterPro
comment: Peptidase_M17_N

PTHR11963:SF23
type: Resource
database: PANTHER
comment: CYTOSOL AMINOPEPTIDASE
signature sequence match: PANTHER PTHR11963:SF23 match 1

PTHR11963
type: Resource
database: PANTHER
comment: LEUCINE AMINOPEPTIDASE-RELATED
signature sequence match: PANTHER PTHR11963 match 1

PF00883
type: Resource
database: Pfam
comment: Peptidase_M17
signature sequence match: Pfam PF00883 match 1

PF02789
type: Resource
database: Pfam
comment: Peptidase_M17_N
signature sequence match: Pfam PF02789 match 1

PR00481
type: Resource
database: PRINTS
comment: LAMNOPPTDASE

SSF52949
type: Resource
database: SUPFAM
comment: Macro domain-like
signature sequence match: SUPFAM SSF52949 match 1

SSF53187
type: Resource
database: SUPFAM
comment: Zn-dependent exopeptidases
signature sequence match: SUPFAM SSF53187 match 1

PS00631
type: Resource
database: PROSITE
comment: CYTOSOL_AP
signature sequence match: PROSITE PS00631 match 1

SIP4C2E197687D5A48E
type: Structured Name
full name: Probable cytosol aminopeptidase
ec name: 3.4.11.1

SIP8E066A1821A9A88A
type: Structured Name
full name: Leucine aminopeptidase
short name: LAP
ec name: 3.4.11.10

SIP2BA06BA51D2DD54D
type: Structured Name
full name: Leucyl aminopeptidase

pepA
type: Gene
locus name: Bd3755

SIP2B7D4553A0C6296E
type: Function Annotation
comment: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

SIPADEEE18C01448C6D
type: Cofactor Annotation
comment: Binds 2 manganese ions per subunit.
cofactor: CHEBI_29035

SIPDCF845F52A5AA8F0
type: Similarity Annotation
comment: Belongs to the peptidase M17 family.

PRO_0000165723
type: Chain Annotation
comment: Probable cytosol aminopeptidase
mass: 53262
range: 22859178665127982tt1tt500

22859178665127982tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MH10-1

22859178665127982tt500
type: Position
type: ExactPosition
position: 500
reference: Q6MH10-1

22859178665127982tt277
type: Position
type: ExactPosition
position: 277
reference: Q6MH10-1

22859178665127982tt351
type: Position
type: ExactPosition
position: 351
reference: Q6MH10-1

22859178665127982tt265
type: Position
type: ExactPosition
position: 265
reference: Q6MH10-1

22859178665127982tt270
type: Position
type: ExactPosition
position: 270
reference: Q6MH10-1

22859178665127982tt288
type: Position
type: ExactPosition
position: 288
reference: Q6MH10-1

22859178665127982tt347
type: Position
type: ExactPosition
position: 347
reference: Q6MH10-1

22859178665127982tt349
type: Position
type: ExactPosition
position: 349
reference: Q6MH10-1

2
subclass of: CHEBI_29035

1
subclass of: CHEBI_29035

Q6MH10-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 53262
value: MAFNLLNKDIDTLTCPALVVFSKSSSQKDKLAKVTHSEIHKALLPSLEEKTISGKHQETVVFREFSFKGFRHVIVVGLGKENEITHESVRQSMASAYEAIKALNVTEAAVHFDGITAGKKDAADFAKATAEGLILTSYVFNELMSGKKETKEINVHVVSKMGNDKAVKAAFNEGAILGSVVNFSRRLGDLPGNLMTPTILADSAVEGAKGIANLKVTVWDKARIKKEKMGGLLGVSNGSDQEPRFIIMEYKGAAASKKPVCFVGKGLTFDCGGISIKPGAGMEEMKYDMCGGANVIGTLLAIAKLKLKVNAVGLVASTENLINGSATKPGDVHTARNGKTFEVNNTDAEGRLILADALSYATELQPQMIVDAATLTGAMVIALGNTHTGYFTRNSALKTKVEKAAAESGEWVWNMPLTDFHVKDMKGTYADLSNISSGKGAGSATAAAFLEQFVGEGIPWAHFDIAGTGWAVGNRLPYCPKKGASGAMIRTFVEIAKQYT

http://purl.uniprot.org/uniprot/Q6MH10#attribution-5B745BD8E303FB1FA1AC6F6C6041F55D
manual: true
evidence: ECO_0000255
source: MF_00181

Q6MK56
type: Protein
reviewed: true
created: 2004-07-19
modified: 2023-06-28
version: 73
mnemonic: APAG_BDEBA
citation: http://purl.uniprot.org/citations/14752164
conflicting sequence: SIP2F5A07284239F85F
recommended name: SIPAD7EBDCBBA123ACE
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP41C69F299DC097C9
annotation: PRO_0000197937
annotation: SIPA5AF9E45BD443BAA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
sequence: MQKTSIPDFQITAKVVYVPSESRPDEGYHFFAYKITITNTGSTPAQLMSRHWVITDALGKKEEVRGPGVVGLQPKIQPGQTFEYDSACPLTTSTGSMVGRYFFVGESGESFSVEVPEFYLIAPLALH
proteome: Chromosome

Q6MK56-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

EMBL CAE80353.1
comment: Different initiation.

COG2967
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/2.60.40.1470
type: Resource
database: Gene3D
comment: ApaG domain
signature sequence match: Gene3D 2.60.40.1470 match 1

MF_00791
type: Resource
database: HAMAP
comment: ApaG
signature sequence match: HAMAP MF 00791 match 1

IPR007474
type: Resource
database: InterPro
comment: ApaG_domain

IPR036767
type: Resource
database: InterPro
comment: ApaG_sf

IPR023065
type: Resource
database: InterPro
comment: Uncharacterised_ApaG

PTHR47191
type: Resource
database: PANTHER
comment: OS05G0170800 PROTEIN
signature sequence match: PANTHER PTHR47191 match 1

PTHR47191:SF2
type: Resource
database: PANTHER
comment: OS05G0170800 PROTEIN
signature sequence match: PANTHER PTHR47191:SF2 match 1

PF04379
type: Resource
database: Pfam
comment: DUF525
signature sequence match: Pfam PF04379 match 1

SSF110069
type: Resource
database: SUPFAM
comment: ApaG-like
signature sequence match: SUPFAM SSF110069 match 1

PS51087
type: Resource
database: PROSITE
comment: APAG
signature sequence match: PROSITE PS51087 match 1

SIPAD7EBDCBBA123ACE
type: Structured Name
full name: Protein ApaG

apaG
type: Gene
locus name: Bd2556

PRO_0000197937
type: Chain Annotation
comment: Protein ApaG
mass: 14009
range: 22859178715723310tt1tt127

22859178715723310tt1
type: Position
type: ExactPosition
position: 1
reference: MQKTSIPDFQITAKVVYVPSESRPDEGYHFFAYKITITNTGSTPAQLMSRHWVITDALGKKEEVRGPGVVGLQPKIQPGQTFEYDSACPLTTSTGSMVGRYFFVGESGESFSVEVPEFYLIAPLALH

22859178715723310tt127
type: Position
type: ExactPosition
position: 127
reference: MQKTSIPDFQITAKVVYVPSESRPDEGYHFFAYKITITNTGSTPAQLMSRHWVITDALGKKEEVRGPGVVGLQPKIQPGQTFEYDSACPLTTSTGSMVGRYFFVGESGESFSVEVPEFYLIAPLALH

SIPA5AF9E45BD443BAA
type: Domain Extent Annotation
comment: ApaG
range: 22859178715723310tt3tt127

22859178715723310tt3
type: Position
type: ExactPosition
position: 3
reference: MQKTSIPDFQITAKVVYVPSESRPDEGYHFFAYKITITNTGSTPAQLMSRHWVITDALGKKEEVRGPGVVGLQPKIQPGQTFEYDSACPLTTSTGSMVGRYFFVGESGESFSVEVPEFYLIAPLALH

MQKTSIPDFQITAKVVYVPSESRPDEGYHFFAYKITITNTGSTPAQLMSRHWVITDALGKKEEVRGPGVVGLQPKIQPGQTFEYDSACPLTTSTGSMVGRYFFVGESGESFSVEVPEFYLIAPLALH
type: Simple Sequence
modified: 2004-07-19
version: 2
mass: 14009

http://purl.uniprot.org/uniprot/Q6MK56#attribution-EC2A511A58BDD012365E19A4E0100665
manual: true
evidence: ECO_0000255
source: MF_00791

http://purl.uniprot.org/uniprot/Q6MK56#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6MPK7
type: Protein
reviewed: true
created: 2005-03-15
modified: 2023-06-28
version: 97
mnemonic: APT_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPC62527ADDBF300CB
enzyme: http://purl.uniprot.org/enzyme/2.4.2.7
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPFECB9A233E883FF9
annotation: SIP0128324098E8331C
annotation: SIPD6F91D3123FD0AF6
annotation: SIPF9350725CF793029
annotation: SIP300B093CF672DC20
annotation: SIP8F6CDD1700A0B3BB
annotation: PRO_0000149356
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/328
classified with: http://purl.uniprot.org/keywords/660
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003999
classified with: GO_0006168
classified with: GO_0044209
classified with: GO_0006166
sequence: MDLKSLIRDVPDFPKPGIIFRDMSPLLQNAEALSFVSHNLLKHVDLTHVDYFAGIESRGFILAAHMAATHKKGFLPIRKAGKLPPPTRKVSYALEYGTAEIELPPGRGNVVIVDDVLATGGTLQAAIDLCLLAGYSVESVAVLVNLTFLNKMTYNDQKVASLVQY
proteome: Chromosome

Q6MPK7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0503
type: Resource
database: eggNOG
comment: Bacteria

cd06223
type: Resource
database: CDD
comment: PRTases_typeI
signature sequence match: CDD cd06223 match 1

MF_00004
type: Resource
database: HAMAP
comment: Aden_phosphoribosyltr
signature sequence match: HAMAP MF 00004 match 1

IPR005764
type: Resource
database: InterPro
comment: Ade_phspho_trans

IPR000836
type: Resource
database: InterPro
comment: PRibTrfase_dom

IPR029057
type: Resource
database: InterPro
comment: PRTase-like

PTHR32315
type: Resource
database: PANTHER
comment: ADENINE PHOSPHORIBOSYLTRANSFERASE
signature sequence match: PANTHER PTHR32315 match 1

PTHR32315:SF3
type: Resource
database: PANTHER
comment: ADENINE PHOSPHORIBOSYLTRANSFERASE
signature sequence match: PANTHER PTHR32315:SF3 match 1

PF00156
type: Resource
database: Pfam
comment: Pribosyltran
signature sequence match: Pfam PF00156 match 1

SSF53271
type: Resource
database: SUPFAM
comment: PRTase-like
signature sequence match: SUPFAM SSF53271 match 1

PS00103
type: Resource
database: PROSITE
comment: PUR_PYR_PR_TRANSFER
signature sequence match: PROSITE PS00103 match 1

SIPC62527ADDBF300CB
type: Structured Name
full name: Adenine phosphoribosyltransferase
short name: APRT
ec name: 2.4.2.7

apt
type: Gene
locus name: Bd0845

SIPFECB9A233E883FF9
type: Function Annotation
comment: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

SIPF9350725CF793029
type: Subunit Annotation
comment: Homodimer.

SIP8F6CDD1700A0B3BB
type: Similarity Annotation
comment: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

PRO_0000149356
type: Chain Annotation
comment: Adenine phosphoribosyltransferase
mass: 18006
range: 22859178801051438tt1tt165

22859178801051438tt1
type: Position
type: ExactPosition
position: 1
reference: MDLKSLIRDVPDFPKPGIIFRDMSPLLQNAEALSFVSHNLLKHVDLTHVDYFAGIESRGFILAAHMAATHKKGFLPIRKAGKLPPPTRKVSYALEYGTAEIELPPGRGNVVIVDDVLATGGTLQAAIDLCLLAGYSVESVAVLVNLTFLNKMTYNDQKVASLVQY

22859178801051438tt165
type: Position
type: ExactPosition
position: 165
reference: MDLKSLIRDVPDFPKPGIIFRDMSPLLQNAEALSFVSHNLLKHVDLTHVDYFAGIESRGFILAAHMAATHKKGFLPIRKAGKLPPPTRKVSYALEYGTAEIELPPGRGNVVIVDDVLATGGTLQAAIDLCLLAGYSVESVAVLVNLTFLNKMTYNDQKVASLVQY

MDLKSLIRDVPDFPKPGIIFRDMSPLLQNAEALSFVSHNLLKHVDLTHVDYFAGIESRGFILAAHMAATHKKGFLPIRKAGKLPPPTRKVSYALEYGTAEIELPPGRGNVVIVDDVLATGGTLQAAIDLCLLAGYSVESVAVLVNLTFLNKMTYNDQKVASLVQY
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 18006

http://purl.uniprot.org/uniprot/Q6MPK7#attribution-0F27B14A644DA8A39AD9BF322F5FDB4F
manual: true
evidence: ECO_0000255
source: MF_00004

Q6MHP7
type: Protein
reviewed: true
created: 2011-03-08
modified: 2023-09-13
version: 106
mnemonic: AROC_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP26EDFBEC82708729
alternative name: SIPE4438FB08936EFF5
enzyme: http://purl.uniprot.org/enzyme/4.2.3.5
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPB922396607F31752
annotation: SIP8B9AB488D11483F0
annotation: SIP62165895DDE99AB7
annotation: SIPDFD756118088AC57
annotation: SIP369E601DA28C4B52
annotation: SIP8027590CDDBD4320
annotation: PRO_0000405965
annotation: SIP44D1DD2B9489A1BF
annotation: SIP46ACB69BD06E762E
annotation: SIPBB30874C079AA3CD
annotation: SIPC83EF77F9F42EF63
annotation: SIP143BA3A0636974DF
annotation: SIPFB2EB213CBC18AC0
annotation: SIP3781642D0170B10C
annotation: SIP96D1576EE5A5E2BE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/57
classified with: http://purl.uniprot.org/keywords/274
classified with: http://purl.uniprot.org/keywords/288
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004107
classified with: GO_0008652
classified with: GO_0009073
classified with: GO_0009423
sequence: Q6MHP7-1
proteome: Chromosome

Q6MHP7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0082
type: Resource
database: eggNOG
comment: Bacteria

cd07304
type: Resource
database: CDD
comment: Chorismate_synthase
signature sequence match: CDD cd07304 match 1

http://purl.uniprot.org/gene3d/3.60.150.10
type: Resource
database: Gene3D
comment: Chorismate synthase AroC
signature sequence match: Gene3D 3.60.150.10 match 1

MF_00300
type: Resource
database: HAMAP
comment: Chorismate_synth
signature sequence match: HAMAP MF 00300 match 1

IPR000453
type: Resource
database: InterPro
comment: Chorismate_synth

IPR035904
type: Resource
database: InterPro
comment: Chorismate_synth_AroC_sf

IPR020541
type: Resource
database: InterPro
comment: Chorismate_synthase_CS

TIGR00033
type: Resource
database: NCBIfam
comment: aroC
signature sequence match: NCBIfam TIGR00033 match 1

PTHR21085
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085 match 1

PTHR21085:SF0
type: Resource
database: PANTHER
comment: CHORISMATE SYNTHASE
signature sequence match: PANTHER PTHR21085:SF0 match 1

PF01264
type: Resource
database: Pfam
comment: Chorismate_synt
signature sequence match: Pfam PF01264 match 1

PIRSF001456
type: Resource
database: PIRSF
comment: Chorismate_synth
signature sequence match: PIRSF PIRSF001456 match 1

SSF103263
type: Resource
database: SUPFAM
comment: Chorismate synthase, AroC
signature sequence match: SUPFAM SSF103263 match 1

PS00787
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_1
signature sequence match: PROSITE PS00787 match 1

PS00788
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_2
signature sequence match: PROSITE PS00788 match 1

PS00789
type: Resource
database: PROSITE
comment: CHORISMATE_SYNTHASE_3
signature sequence match: PROSITE PS00789 match 1

SIP26EDFBEC82708729
type: Structured Name
full name: Chorismate synthase
short name: CS
ec name: 4.2.3.5

SIPE4438FB08936EFF5
type: Structured Name
full name: 5-enolpyruvylshikimate-3-phosphate phospholyase

aroC
type: Gene
locus name: Bd3493

SIPB922396607F31752
type: Function Annotation
comment: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

SIP62165895DDE99AB7
type: Cofactor Annotation
comment: Reduced FMN (FMNH(2)).
cofactor: CHEBI_57618

SIP369E601DA28C4B52
type: Subunit Annotation
comment: Homotetramer.

SIP8027590CDDBD4320
type: Similarity Annotation
comment: Belongs to the chorismate synthase family.

PRO_0000405965
type: Chain Annotation
comment: Chorismate synthase
mass: 36702
range: 22859178667161390tt1tt341

22859178667161390tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MHP7-1

22859178667161390tt341
type: Position
type: ExactPosition
position: 341
reference: Q6MHP7-1

SIP44D1DD2B9489A1BF
type: Region Annotation
comment: Disordered
range: 22859178667161390tt45tt64

22859178667161390tt45
type: Position
type: ExactPosition
position: 45
reference: Q6MHP7-1

22859178667161390tt64
type: Position
type: ExactPosition
position: 64
reference: Q6MHP7-1

SIP46ACB69BD06E762E
type: Region Annotation
comment: Disordered
range: 22859178667161390tt109tt134

22859178667161390tt109
type: Position
type: ExactPosition
position: 109
reference: Q6MHP7-1

22859178667161390tt134
type: Position
type: ExactPosition
position: 134
reference: Q6MHP7-1

SIPBB30874C079AA3CD
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 22859178667161390tt109tt130

22859178667161390tt130
type: Position
type: ExactPosition
position: 130
reference: Q6MHP7-1

22859178667161390tt48
type: Position
type: ExactPosition
position: 48
reference: Q6MHP7-1

22859178667161390tt128
type: Position
type: ExactPosition
position: 128
reference: Q6MHP7-1

22859178667161390tt280
type: Position
type: ExactPosition
position: 280
reference: Q6MHP7-1

22859178667161390tt295
type: Position
type: ExactPosition
position: 295
reference: Q6MHP7-1

22859178667161390tt299
type: Position
type: ExactPosition
position: 299
reference: Q6MHP7-1

22859178667161390tt308
type: Position
type: ExactPosition
position: 308
reference: Q6MHP7-1

Q6MHP7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 36702
value: MSASQFGSRFVITTFGESHGTALGVVIDGCPAGVNFDEGLLKKELERRRPGHHGSGQIVSGRQETDAPEVLSGVFDGKTLGTPMAIIVRNQDARSQDYSVIKNSPRAGHADDMWRNKFGHSDHRGGGRSSGRETVSRVMAGSVAQMMMKHVSAPTKVIGYASQIGPMTLTDAERAEVSKKDIDSFQARFPSSRDQEVADLLKKAQDNGESHGGVAEILIQNPPAHLGQPVFHKLKSDLAMAFLSVGATNGFELGLGFEAAEVKGTQFHQGPQDAYGGIRGGISTGESILLRVSFKPTSSILDVAKKGRHDPCIVTRAIPVLEAMTWLVLADHYLWSKTDRI

http://purl.uniprot.org/uniprot/Q6MHP7#attribution-2F3E6EDFAEDDC061C716E49B15F505C7
manual: true
evidence: ECO_0000255
source: MF_00300

Q6MRR3
type: Protein
reviewed: true
created: 2009-02-10
modified: 2023-09-13
version: 110
mnemonic: ATP6_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP01806B802B154B42
alternative name: SIPAAE750EF5DEF8F79
alternative name: SIPB64859FA922E406A
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPAA9CA1B326A75703
annotation: SIP94E00D7ECA932A03
annotation: SIPEAD0B67C94447603
annotation: SIPB1E6C8F36A723DD8
annotation: PRO_0000362244
annotation: SIPD5C12C472A29F411
annotation: SIPE0F5D95AD5D7DB94
annotation: SIPE9D7F2F8081E2C65
annotation: SIPEAF63C3D21146346
annotation: SIP05A9B522A2C698A9
annotation: SIP1AF06BA256258408
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: Q6MRR3-1
proteome: Chromosome

Q6MRR3-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0356
type: Resource
database: eggNOG
comment: Bacteria

cd00310
type: Resource
database: CDD
comment: ATP-synt_Fo_a_6
signature sequence match: CDD cd00310 match 1

http://purl.uniprot.org/gene3d/1.20.120.220
type: Resource
database: Gene3D
comment: ATP synthase, F0 complex, subunit A
signature sequence match: Gene3D 1.20.120.220 match 1

MF_01393
type: Resource
database: HAMAP
comment: ATP_synth_a_bact
signature sequence match: HAMAP MF 01393 match 1

IPR045082
type: Resource
database: InterPro
comment: ATP_syn_F0_a_bact/chloroplast

IPR000568
type: Resource
database: InterPro
comment: ATP_synth_F0_asu

IPR035908
type: Resource
database: InterPro
comment: F0_ATP_A_sf

TIGR01131
type: Resource
database: NCBIfam
comment: ATP_synt_6_or_A
signature sequence match: NCBIfam TIGR01131 match 1

PTHR42823
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT A, CHLOROPLASTIC
signature sequence match: PANTHER PTHR42823 match 1

PTHR42823:SF3
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT A, CHLOROPLASTIC
signature sequence match: PANTHER PTHR42823:SF3 match 1

PF00119
type: Resource
database: Pfam
comment: ATP-synt_A
signature sequence match: Pfam PF00119 match 1

PR00123
type: Resource
database: PRINTS
comment: ATPASEA

SSF81336
type: Resource
database: SUPFAM
comment: F1F0 ATP synthase subunit A
signature sequence match: SUPFAM SSF81336 match 1

SIP01806B802B154B42
type: Structured Name
full name: ATP synthase subunit a

SIPAAE750EF5DEF8F79
type: Structured Name
full name: ATP synthase F0 sector subunit a

SIPB64859FA922E406A
type: Structured Name
full name: F-ATPase subunit 6

atpB
type: Gene
locus name: Bd0009

SIPAA9CA1B326A75703
type: Function Annotation
comment: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

SIP94E00D7ECA932A03
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIPB1E6C8F36A723DD8
type: Similarity Annotation
comment: Belongs to the ATPase A chain family.

PRO_0000362244
type: Chain Annotation
comment: ATP synthase subunit a
mass: 24920
range: 22859178835063598tt1tt229

22859178835063598tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRR3-1

22859178835063598tt229
type: Position
type: ExactPosition
position: 229
reference: Q6MRR3-1

SIPD5C12C472A29F411
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt16tt36

22859178835063598tt16
type: Position
type: ExactPosition
position: 16
reference: Q6MRR3-1

22859178835063598tt36
type: Position
type: ExactPosition
position: 36
reference: Q6MRR3-1

SIPE0F5D95AD5D7DB94
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt81tt101

22859178835063598tt81
type: Position
type: ExactPosition
position: 81
reference: Q6MRR3-1

22859178835063598tt101
type: Position
type: ExactPosition
position: 101
reference: Q6MRR3-1

SIPE9D7F2F8081E2C65
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt110tt130

22859178835063598tt110
type: Position
type: ExactPosition
position: 110
reference: Q6MRR3-1

22859178835063598tt130
type: Position
type: ExactPosition
position: 130
reference: Q6MRR3-1

SIPEAF63C3D21146346
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt142tt162

22859178835063598tt142
type: Position
type: ExactPosition
position: 142
reference: Q6MRR3-1

22859178835063598tt162
type: Position
type: ExactPosition
position: 162
reference: Q6MRR3-1

SIP05A9B522A2C698A9
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt175tt195

22859178835063598tt175
type: Position
type: ExactPosition
position: 175
reference: Q6MRR3-1

22859178835063598tt195
type: Position
type: ExactPosition
position: 195
reference: Q6MRR3-1

SIP1AF06BA256258408
type: Transmembrane Annotation
comment: Helical
range: 22859178835063598tt196tt216

22859178835063598tt196
type: Position
type: ExactPosition
position: 196
reference: Q6MRR3-1

22859178835063598tt216
type: Position
type: ExactPosition
position: 216
reference: Q6MRR3-1

Q6MRR3-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 24920
value: MSFNWTQLVPGVGHEYAHVATLGIATVAAVGIGAAARASLGKGEAAVLPASKFSLRGIFELLTEMTSGLADMVIGEHGKHYIPFFASVFFFILFNNLLGMIPGMTPATENMNTTFGFGVLMFLFYNFQGVKENGPVAYLKHFMGPVIFLAPLMFVIEIVSHIVRPFSLGLRLANVMMGDHTVLSVFLDLVPIGVPIPFYVMGLFVCFVQAFVFTLLSMVYVAFAIAHDH

http://purl.uniprot.org/uniprot/Q6MRR3#attribution-D994E701E2B83728CB99F3F29F0E9616
manual: true
evidence: ECO_0000255
source: MF_01393

Q6MGM5
type: Protein
reviewed: true
created: 2006-05-30
modified: 2023-09-13
version: 124
mnemonic: ATPA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPBE7712CDD879D1B2
alternative name: SIP605D291825F99072
alternative name: SIPA3FE03A31043C3FE
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP7EC2913333CD7296
annotation: SIP5D5644F011E555FB
annotation: SIPFDABE5D5D42CC706
annotation: SIP5728466D1148482B
annotation: SIP69A87AB3D84275E7
annotation: PRO_0000238204
annotation: SIPAD9D69B31A9014EC
annotation: SIP9E49B48FB76B6D9D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: Q6MGM5-1
proteome: Chromosome

Q6MGM5-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0056
type: Resource
database: eggNOG
comment: Bacteria

cd18113
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_C
signature sequence match: CDD cd18113 match 1

cd18116
type: Resource
database: CDD
comment: ATP-synt_F1_alpha_N
signature sequence match: CDD cd18116 match 1

cd01132
type: Resource
database: CDD
comment: F1-ATPase_alpha_CD
signature sequence match: CDD cd01132 match 1

http://purl.uniprot.org/gene3d/1.20.150.20
type: Resource
database: Gene3D
comment: ATP synthase alpha/beta chain, C-terminal domain
signature sequence match: Gene3D 1.20.150.20 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1
signature sequence match: Gene3D 3.40.50.300 match 2
signature sequence match: Gene3D 3.40.50.300 match 3

MF_01346
type: Resource
database: HAMAP
comment: ATP_synth_alpha_bact
signature sequence match: HAMAP MF 01346 match 1

IPR023366
type: Resource
database: InterPro
comment: ATP_synth_asu-like_sf

IPR000793
type: Resource
database: InterPro
comment: ATP_synth_asu_C

IPR038376
type: Resource
database: InterPro
comment: ATP_synth_asu_C_sf

IPR033732
type: Resource
database: InterPro
comment: ATP_synth_F1_a_nt-bd_dom

IPR005294
type: Resource
database: InterPro
comment: ATP_synth_F1_asu

IPR004100
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N

IPR036121
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_N_sf

IPR000194
type: Resource
database: InterPro
comment: ATPase_F1/V1/A1_a/bsu_nucl-bd

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

TIGR00962
type: Resource
database: NCBIfam
comment: atpA
signature sequence match: NCBIfam TIGR00962 match 1

PTHR48082
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082 match 1

PTHR48082:SF2
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48082:SF2 match 1

PF00006
type: Resource
database: Pfam
comment: ATP-synt_ab
signature sequence match: Pfam PF00006 match 1

PF00306
type: Resource
database: Pfam
comment: ATP-synt_ab_C
signature sequence match: Pfam PF00306 match 1

PF02874
type: Resource
database: Pfam
comment: ATP-synt_ab_N
signature sequence match: Pfam PF02874 match 1

PIRSF039088
type: Resource
database: PIRSF
comment: F_ATPase_subunit_alpha
signature sequence match: PIRSF PIRSF039088 match 1

SSF47917
type: Resource
database: SUPFAM
comment: C-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF47917 match 1

SSF50615
type: Resource
database: SUPFAM
comment: N-terminal domain of alpha and beta subunits of F1 ATP synthase
signature sequence match: SUPFAM SSF50615 match 1

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1
signature sequence match: SUPFAM SSF52540 match 2

SIPBE7712CDD879D1B2
type: Structured Name
full name: ATP synthase subunit alpha
ec name: 7.1.2.2

SIP605D291825F99072
type: Structured Name
full name: ATP synthase F1 sector subunit alpha

SIPA3FE03A31043C3FE
type: Structured Name
full name: F-ATPase subunit alpha

atpA
type: Gene
locus name: Bd3899

SIP7EC2913333CD7296
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

SIPFDABE5D5D42CC706
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP69A87AB3D84275E7
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_0000238204
type: Chain Annotation
comment: ATP synthase subunit alpha
mass: 55370
range: 22859178650187054tt1tt507

22859178650187054tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MGM5-1

22859178650187054tt507
type: Position
type: ExactPosition
position: 507
reference: Q6MGM5-1

22859178650187054tt171
type: Position
type: ExactPosition
position: 171
reference: Q6MGM5-1

22859178650187054tt178
type: Position
type: ExactPosition
position: 178
reference: Q6MGM5-1

SIP9E49B48FB76B6D9D
type: Site Annotation
comment: Required for activity
range: 22859178650187054tt364tt364

22859178650187054tt364
type: Position
type: ExactPosition
position: 364
reference: Q6MGM5-1

Q6MGM5-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 55370
value: METQIRADEISRVLKEQINQYNKKIEVSETGSVLSVGDGVARIYGLENAMAGELVEFPGEVFGMVLNLEEGYVGAVLFGEDRHIKEGDVVKRTKKIVSVPVGEALLGRVVDALGNPIDGRGAINTPHSRIVETKAPGIVYRHPVEEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAVDTIINQKGLNVQCFYVAIGQKQSTVALVVEKLRAAGALEYTTVIAANASDPAPLQYLAAYSGTAMAEYFRDTGRHALIVYDDLTKQAQAYRQLSLLLRRPPGREAYPGDVFYCHSRLLERASKLSADKGGGSLTALPIIETQAGDISAYIPTNVISITDGQIFLESDLFYKGVRPAISVGKSVSRVGGAAQIKAMKQVAGSLKLELAQFRSMEAFAAFASDLDKASQQQLARGRRLIEVLKQPQYSPVKVEEQIIMIFAAGNAFVDQYPETDVKRYEKEMIEFLKNKHSDIIKTISEKKAIADDTKKALLAALEEFKAIFQPSNK

http://purl.uniprot.org/uniprot/Q6MGM5#attribution-5C1C7D08C5C30A92BBCA3D89004F22BF
manual: true
evidence: ECO_0000255
source: MF_01346

Q6MGM7
type: Protein
reviewed: true
created: 2006-10-31
modified: 2023-09-13
version: 125
mnemonic: ATPB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPCABF2B7C796C67AF
alternative name: SIP54BDE05048B44533
alternative name: SIPE5DC476874342920
enzyme: http://purl.uniprot.org/enzyme/7.1.2.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP503AA1A0B10097CA
annotation: SIP411B78E2AFB68591
annotation: SIPC5FE21F5C932F834
annotation: SIPB4FE508C065D0902
annotation: SIP75690A1DB36B306A
annotation: PRO_0000254217
annotation: SIPCACBFC0EA6A673B3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1278
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0046961
sequence: Q6MGM7-1
proteome: Chromosome

Q6MGM7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0055
type: Resource
database: eggNOG
comment: Bacteria

cd18110
type: Resource
database: CDD
comment: ATP-synt_F1_beta_C
signature sequence match: CDD cd18110 match 1

cd18115
type: Resource
database: CDD
comment: ATP-synt_F1_beta_N
signature sequence match: CDD cd18115 match 1

cd01133
type: Resource
database: CDD
comment: F1-ATPase_beta_CD
signature sequence match: CDD cd01133 match 1

MF_01347
type: Resource
database: HAMAP
comment: ATP_synth_beta_bact
signature sequence match: HAMAP MF 01347 match 1

IPR003593
type: Resource
database: InterPro
comment: AAA+_ATPase

IPR005722
type: Resource
database: InterPro
comment: ATP_synth_F1_bsu

IPR020003
type: Resource
database: InterPro
comment: ATPase_a/bsu_AS

IPR024034
type: Resource
database: InterPro
comment: ATPase_F1/V1_b/a_C

TIGR01039
type: Resource
database: NCBIfam
comment: atpD
signature sequence match: NCBIfam TIGR01039 match 1

PTHR15184
type: Resource
database: PANTHER
comment: ATP SYNTHASE
signature sequence match: PANTHER PTHR15184 match 1

PTHR15184:SF71
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR15184:SF71 match 1

SM00382
type: Resource
database: SMART
comment: AAA
signature sequence match: SMART SM00382 match 1
signature sequence match: SMART SM00382 match 2

PS00152
type: Resource
database: PROSITE
comment: ATPASE_ALPHA_BETA
signature sequence match: PROSITE PS00152 match 1

SIPCABF2B7C796C67AF
type: Structured Name
full name: ATP synthase subunit beta
ec name: 7.1.2.2

SIP54BDE05048B44533
type: Structured Name
full name: ATP synthase F1 sector subunit beta

SIPE5DC476874342920
type: Structured Name
full name: F-ATPase subunit beta

atpD
type: Gene
locus name: Bd3897

SIP503AA1A0B10097CA
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

SIPC5FE21F5C932F834
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP75690A1DB36B306A
type: Similarity Annotation
comment: Belongs to the ATPase alpha/beta chains family.

PRO_0000254217
type: Chain Annotation
comment: ATP synthase subunit beta
mass: 50802
range: 22859178650187566tt1tt468

22859178650187566tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MGM7-1

22859178650187566tt468
type: Position
type: ExactPosition
position: 468
reference: Q6MGM7-1

22859178650187566tt155
type: Position
type: ExactPosition
position: 155
reference: Q6MGM7-1

22859178650187566tt162
type: Position
type: ExactPosition
position: 162
reference: Q6MGM7-1

Q6MGM7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 50802
value: MAFGKVKQVMGPVVDVEFEGGELPAINSALRVSNKFISDVEFNLVLEVAQHLGDGVVRTISMDQTEGLVRGEKVKALGTQITAPVGREALGRIINVVGEPIDEMGPVNAKEQWGIHRTAPKFEDQATAAAMLMTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIQELIRNIATEHGGFSVFAGVGERTREGNDLWQEMKQSGVLAKTSLVFGQMNEPPGARARVALTGLTVAEYFRDVENQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATEMGTLQERITSTKKGSITSVQAVYVPADDYTDPAPATTFTHLDATTNLDRDIAAMAIFPAVHPLTSTSRLLDPTVIGEEHYKCARDVQALLQRNRELQDIIAILGMDELSESDKLVVSRSRKIQRFLSQPFFVAEQFTGLPGKYVDIKDTVKGFREILDGKHDALPEQAFYLVGTIEDAIEKAKKLQA

http://purl.uniprot.org/uniprot/Q6MGM7#attribution-43A9882434E9506AAFC23F741E3F28D4
manual: true
evidence: ECO_0000255
source: MF_01347

Q6MGM4
type: Protein
reviewed: true
created: 2009-09-01
modified: 2023-09-13
version: 99
mnemonic: ATPD_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPBD1370672D799AB1
alternative name: SIP998F9CFFBC003414
alternative name: SIP3196E599EDF744CD
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP7108E4820C40D509
annotation: SIP1BC06A972040417A
annotation: SIP96DA0A4070C3DDEF
annotation: SIP854477FC9A98E96F
annotation: SIP1FB345C7F2E98FE0
annotation: PRO_0000382059
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0046933
sequence: MRVSEISKRYAKALLAVAKQKGIHTQVHAELQALVKSFAGDVSVKNYFENPMIGSDQKIAAVKASLSGKGVSEEVVNTLVLLAEKNRFGVLEQISFAYRDLLDLEEGVTRGVVRSAQPLAADAQKDIEQKITKVLNKKIVLTYEQDPKLLGGIVATVGGWTFDDSIDTHLKKLNEELNRRAN
proteome: Chromosome

Q6MGM4-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0712
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.520.20
type: Resource
database: Gene3D
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: Gene3D 1.10.520.20 match 1

MF_01416
type: Resource
database: HAMAP
comment: ATP_synth_delta_bact
signature sequence match: HAMAP MF 01416 match 1

IPR026015
type: Resource
database: InterPro
comment: ATP_synth_OSCP/delta_N_sf

IPR000711
type: Resource
database: InterPro
comment: ATPase_OSCP/dsu

TIGR01145
type: Resource
database: NCBIfam
comment: ATP_synt_delta
signature sequence match: NCBIfam TIGR01145 match 1

PTHR11910
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA CHAIN
signature sequence match: PANTHER PTHR11910 match 1

PTHR11910:SF22
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, CHLOROPLASTIC
signature sequence match: PANTHER PTHR11910:SF22 match 1

PF00213
type: Resource
database: Pfam
comment: OSCP
signature sequence match: Pfam PF00213 match 1

PR00125
type: Resource
database: PRINTS
comment: ATPASEDELTA

SSF47928
type: Resource
database: SUPFAM
comment: N-terminal domain of the delta subunit of the F1F0-ATP synthase
signature sequence match: SUPFAM SSF47928 match 1

SIPBD1370672D799AB1
type: Structured Name
full name: ATP synthase subunit delta

SIP998F9CFFBC003414
type: Structured Name
full name: ATP synthase F(1) sector subunit delta

SIP3196E599EDF744CD
type: Structured Name
full name: F-type ATPase subunit delta
short name: F-ATPase subunit delta

atpH
type: Gene
locus name: Bd3900

SIP7108E4820C40D509
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP1BC06A972040417A
type: Function Annotation
comment: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

SIP96DA0A4070C3DDEF
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP1FB345C7F2E98FE0
type: Similarity Annotation
comment: Belongs to the ATPase delta chain family.

PRO_0000382059
type: Chain Annotation
comment: ATP synthase subunit delta
mass: 20019
range: 22859178650186798tt1tt182

22859178650186798tt1
type: Position
type: ExactPosition
position: 1
reference: MRVSEISKRYAKALLAVAKQKGIHTQVHAELQALVKSFAGDVSVKNYFENPMIGSDQKIAAVKASLSGKGVSEEVVNTLVLLAEKNRFGVLEQISFAYRDLLDLEEGVTRGVVRSAQPLAADAQKDIEQKITKVLNKKIVLTYEQDPKLLGGIVATVGGWTFDDSIDTHLKKLNEELNRRAN

22859178650186798tt182
type: Position
type: ExactPosition
position: 182
reference: MRVSEISKRYAKALLAVAKQKGIHTQVHAELQALVKSFAGDVSVKNYFENPMIGSDQKIAAVKASLSGKGVSEEVVNTLVLLAEKNRFGVLEQISFAYRDLLDLEEGVTRGVVRSAQPLAADAQKDIEQKITKVLNKKIVLTYEQDPKLLGGIVATVGGWTFDDSIDTHLKKLNEELNRRAN

MRVSEISKRYAKALLAVAKQKGIHTQVHAELQALVKSFAGDVSVKNYFENPMIGSDQKIAAVKASLSGKGVSEEVVNTLVLLAEKNRFGVLEQISFAYRDLLDLEEGVTRGVVRSAQPLAADAQKDIEQKITKVLNKKIVLTYEQDPKLLGGIVATVGGWTFDDSIDTHLKKLNEELNRRAN
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 20019

http://purl.uniprot.org/uniprot/Q6MGM4#attribution-B1DD1792DF5CD88DBD7981631B7C9A70
manual: true
evidence: ECO_0000255
source: MF_01416

Q6MGM8
type: Protein
reviewed: true
created: 2005-03-01
modified: 2023-09-13
version: 103
mnemonic: ATPE_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP45B225C96B5B8720
alternative name: SIP1A3B8E10330D1A15
alternative name: SIPA309F3952E20E34C
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP60EC2C43BDED14DD
annotation: SIP13B7116D904F7B12
annotation: SIPD7BDD20927C43681
annotation: SIPAE537E0F8090B814
annotation: PRO_0000188104
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
sequence: MNMKLTIVTPEKRILVGQEVDEVTVPAFKGELNILPGHAPLITTLETGVMKWKLKGKEKQDLAVISWGYCQVSPEGVNILANIADLPEEIDLQATKEFLALSEKKIMNELITDEDWAEFQRDWAHARAKIEAAEQQPAKK
proteome: Chromosome

Q6MGM8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0355
type: Resource
database: eggNOG
comment: Bacteria

cd12152
type: Resource
database: CDD
comment: F1-ATPase_delta
signature sequence match: CDD cd12152 match 1

http://purl.uniprot.org/gene3d/2.60.15.10
type: Resource
database: Gene3D
comment: F0F1 ATP synthase delta/epsilon subunit, N-terminal
signature sequence match: Gene3D 2.60.15.10 match 1

MF_00530
type: Resource
database: HAMAP
comment: ATP_synth_epsil_bac
signature sequence match: HAMAP MF 00530 match 1

IPR001469
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu

IPR020546
type: Resource
database: InterPro
comment: ATP_synth_F1_dsu/esu_N

IPR036771
type: Resource
database: InterPro
comment: ATPsynth_dsu/esu_N

TIGR01216
type: Resource
database: NCBIfam
comment: ATP_synt_epsi
signature sequence match: NCBIfam TIGR01216 match 1

PTHR13822
type: Resource
database: PANTHER
comment: ATP SYNTHASE DELTA/EPSILON CHAIN
signature sequence match: PANTHER PTHR13822 match 1

PTHR13822:SF7
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL
signature sequence match: PANTHER PTHR13822:SF7 match 1

PF02823
type: Resource
database: Pfam
comment: ATP-synt_DE_N
signature sequence match: Pfam PF02823 match 1

SSF51344
type: Resource
database: SUPFAM
comment: Epsilon subunit of F1F0-ATP synthase N-terminal domain
signature sequence match: SUPFAM SSF51344 match 1

SIP45B225C96B5B8720
type: Structured Name
full name: ATP synthase epsilon chain

SIP1A3B8E10330D1A15
type: Structured Name
full name: ATP synthase F1 sector epsilon subunit

SIPA309F3952E20E34C
type: Structured Name
full name: F-ATPase epsilon subunit

atpC
type: Gene
locus name: Bd3896

SIP60EC2C43BDED14DD
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane.

SIP13B7116D904F7B12
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIPAE537E0F8090B814
type: Similarity Annotation
comment: Belongs to the ATPase epsilon chain family.

PRO_0000188104
type: Chain Annotation
comment: ATP synthase epsilon chain
mass: 15737
range: 22859178650187822tt1tt140

22859178650187822tt1
type: Position
type: ExactPosition
position: 1
reference: MNMKLTIVTPEKRILVGQEVDEVTVPAFKGELNILPGHAPLITTLETGVMKWKLKGKEKQDLAVISWGYCQVSPEGVNILANIADLPEEIDLQATKEFLALSEKKIMNELITDEDWAEFQRDWAHARAKIEAAEQQPAKK

22859178650187822tt140
type: Position
type: ExactPosition
position: 140
reference: MNMKLTIVTPEKRILVGQEVDEVTVPAFKGELNILPGHAPLITTLETGVMKWKLKGKEKQDLAVISWGYCQVSPEGVNILANIADLPEEIDLQATKEFLALSEKKIMNELITDEDWAEFQRDWAHARAKIEAAEQQPAKK

MNMKLTIVTPEKRILVGQEVDEVTVPAFKGELNILPGHAPLITTLETGVMKWKLKGKEKQDLAVISWGYCQVSPEGVNILANIADLPEEIDLQATKEFLALSEKKIMNELITDEDWAEFQRDWAHARAKIEAAEQQPAKK
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 15737

http://purl.uniprot.org/uniprot/Q6MGM8#attribution-010E2FDA382798F3C5F7883FA248BBDD
manual: true
evidence: ECO_0000255
source: MF_00530

Q6MGM3
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-06-28
version: 88
mnemonic: ATPF_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP9908B01B6DDF809F
alternative name: SIP2DA520AFF070A505
alternative name: SIP21033C35161E7941
alternative name: SIPAF55909EB1107504
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP928EDA5D2D17CCAE
annotation: SIP95A51BCEBA1D168A
annotation: SIP448875B2E4285717
annotation: SIP11B93D4A3D71BEF8
annotation: SIP67924BAC891D3A7A
annotation: PRO_0000368349
annotation: SIP3515B50F581597F9
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/66
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/138
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0045263
classified with: GO_0046933
sequence: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV
proteome: Chromosome

Q6MGM3-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0711
type: Resource
database: eggNOG
comment: Bacteria

cd06503
type: Resource
database: CDD
comment: ATP-synt_Fo_b
signature sequence match: CDD cd06503 match 1

MF_01398
type: Resource
database: HAMAP
comment: ATP_synth_b_bprime
signature sequence match: HAMAP MF 01398 match 1

IPR002146
type: Resource
database: InterPro
comment: ATP_synth_b/b'su_bac/chlpt

PTHR34264
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B, CHLOROPLASTIC
signature sequence match: PANTHER PTHR34264 match 1

PTHR34264:SF3
type: Resource
database: PANTHER
comment: ATP SYNTHASE SUBUNIT B, CHLOROPLASTIC
signature sequence match: PANTHER PTHR34264:SF3 match 1

PF00430
type: Resource
database: Pfam
comment: ATP-synt_B
signature sequence match: Pfam PF00430 match 1

SIP9908B01B6DDF809F
type: Structured Name
full name: ATP synthase subunit b

SIP2DA520AFF070A505
type: Structured Name
full name: ATP synthase F(0) sector subunit b

SIP21033C35161E7941
type: Structured Name
full name: ATPase subunit I

SIPAF55909EB1107504
type: Structured Name
full name: F-type ATPase subunit b
short name: F-ATPase subunit b

atpF
type: Gene
locus name: Bd3902

SIP928EDA5D2D17CCAE
type: Function Annotation
comment: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.

SIP95A51BCEBA1D168A
type: Function Annotation
comment: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).

SIP448875B2E4285717
type: Subunit Annotation
comment: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

SIP67924BAC891D3A7A
type: Similarity Annotation
comment: Belongs to the ATPase B chain family.

PRO_0000368349
type: Chain Annotation
comment: ATP synthase subunit b
mass: 20689
range: 22859178650186542tt1tt186

22859178650186542tt1
type: Position
type: ExactPosition
position: 1
reference: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV

22859178650186542tt186
type: Position
type: ExactPosition
position: 186
reference: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV

SIP3515B50F581597F9
type: Transmembrane Annotation
comment: Helical
range: 22859178650186542tt5tt25

22859178650186542tt5
type: Position
type: ExactPosition
position: 5
reference: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV

22859178650186542tt25
type: Position
type: ExactPosition
position: 25
reference: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV

MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 20689

http://purl.uniprot.org/uniprot/Q6MGM3#attribution-F532F36C147A4DB2E74653A5DA543EB9
manual: true
evidence: ECO_0000255
source: MF_01398

Q6MGM6
type: Protein
reviewed: true
created: 2005-11-22
modified: 2023-09-13
version: 103
mnemonic: ATPG_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPA74E809999CB5FD8
alternative name: SIP44F0DB08F4BB3CEB
alternative name: SIP4FE115C883A6523F
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP97A8ED23FC5447C2
annotation: SIP8BE23AE546FDAD01
annotation: SIP5F97F917579F8F18
annotation: SIP79951A96D7E4C679
annotation: PRO_0000073241
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/139
classified with: http://purl.uniprot.org/keywords/375
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005886
classified with: GO_0045261
classified with: GO_0005524
classified with: GO_0046933
classified with: GO_0042777
sequence: Q6MGM6-1
proteome: Chromosome

Q6MGM6-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0224
type: Resource
database: eggNOG
comment: Bacteria

cd12151
type: Resource
database: CDD
comment: F1-ATPase_gamma
signature sequence match: CDD cd12151 match 1

http://purl.uniprot.org/gene3d/1.10.287.80
type: Resource
database: Gene3D
comment: ATP synthase, gamma subunit, helix hairpin domain
signature sequence match: Gene3D 1.10.287.80 match 1
signature sequence match: Gene3D 1.10.287.80 match 2

MF_00815
type: Resource
database: HAMAP
comment: ATP_synth_gamma_bact
signature sequence match: HAMAP MF 00815 match 1

IPR035968
type: Resource
database: InterPro
comment: ATP_synth_F1_ATPase_gsu

IPR000131
type: Resource
database: InterPro
comment: ATP_synth_F1_gsu

IPR023632
type: Resource
database: InterPro
comment: ATP_synth_F1_gsu_CS

TIGR01146
type: Resource
database: NCBIfam
comment: ATPsyn_F1gamma
signature sequence match: NCBIfam TIGR01146 match 1

PTHR11693
type: Resource
database: PANTHER
comment: ATP SYNTHASE GAMMA CHAIN
signature sequence match: PANTHER PTHR11693 match 1

PTHR11693:SF41
type: Resource
database: PANTHER
comment: ATP SYNTHASE GAMMA CHAIN
signature sequence match: PANTHER PTHR11693:SF41 match 1

PF00231
type: Resource
database: Pfam
comment: ATP-synt
signature sequence match: Pfam PF00231 match 1

PR00126
type: Resource
database: PRINTS
comment: ATPASEGAMMA

SSF52943
type: Resource
database: SUPFAM
comment: ATP synthase (F1-ATPase), gamma subunit
signature sequence match: SUPFAM SSF52943 match 1

PS00153
type: Resource
database: PROSITE
comment: ATPASE_GAMMA
signature sequence match: PROSITE PS00153 match 1

SIPA74E809999CB5FD8
type: Structured Name
full name: ATP synthase gamma chain

SIP44F0DB08F4BB3CEB
type: Structured Name
full name: ATP synthase F1 sector gamma subunit

SIP4FE115C883A6523F
type: Structured Name
full name: F-ATPase gamma subunit

atpG
type: Gene
locus name: Bd3898

SIP97A8ED23FC5447C2
type: Function Annotation
comment: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

SIP8BE23AE546FDAD01
type: Subunit Annotation
comment: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

SIP79951A96D7E4C679
type: Similarity Annotation
comment: Belongs to the ATPase gamma chain family.

PRO_0000073241
type: Chain Annotation
comment: ATP synthase gamma chain
mass: 33164
range: 22859178650187310tt1tt295

22859178650187310tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MGM6-1

22859178650187310tt295
type: Position
type: ExactPosition
position: 295
reference: Q6MGM6-1

Q6MGM6-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 33164
value: MASLKDIRAQIESTKNTQQITKAMKLVSAAKLRKAQNNIVNMRPYALALRQVIADIAVTNKVSHPLMEKKEQVKNVLLVVITSDRGLCGAFNSNINKFAEAYYNSNKASLEKIDFLFVGRRGHDYFARRGIKAVDYITKLDKDISYELASKVANRVMNDYLEGSYDEVRIVHNEFKSAISQVVTAETLLPIDLGMTTFKKEADTASNFAVDMIFEPAPEQIIKELLEKHFELQVYRCMSESVAGEHGARMSAMENATNNAKEMINKLTLTYNKLRQEKITTELIEIVSGAEALKG

http://purl.uniprot.org/uniprot/Q6MGM6#attribution-0FB3B03FF09B8F0EFB536369EB58B6C4
manual: true
evidence: ECO_0000255
source: MF_00815

Q6MRI1
type: Protein
reviewed: true
created: 2005-02-15
modified: 2023-09-13
version: 104
mnemonic: CH60_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPF255B4347D4E348A
alternative name: SIPE5C33196A30979CA
alternative name: SIPE325E657B082D974
enzyme: http://purl.uniprot.org/enzyme/5.6.1.7
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP1C8CA1D28E38E934
annotation: SIP11CB6D51E8E69FCF
annotation: SIP74E49C31A7580F2C
annotation: SIPAAEDD7ECECF39F49
annotation: SIPB63F48F99CD9A3B4
annotation: PRO_0000063285
annotation: SIPC1CF96858DC3FAB4
annotation: SIP5FE7FB3FEEED7E18
annotation: SIP2BC41BE3BF1E86C7
annotation: SIP28A1E280CC0D7C8D
annotation: SIP59592FE148E92D4C
annotation: SIP03598962300D4ECD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0140662
classified with: GO_0016853
classified with: GO_0051082
classified with: GO_0042026
sequence: Q6MRI1-1
proteome: Chromosome

Q6MRI1-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0459
type: Resource
database: eggNOG
comment: Bacteria

cd03344
type: Resource
database: CDD
comment: GroEL
signature sequence match: CDD cd03344 match 1

http://purl.uniprot.org/gene3d/3.50.7.10
type: Resource
database: Gene3D
comment: GroEL
signature sequence match: Gene3D 3.50.7.10 match 1

http://purl.uniprot.org/gene3d/1.10.560.10
type: Resource
database: Gene3D
comment: GroEL-like equatorial domain
signature sequence match: Gene3D 1.10.560.10 match 1

http://purl.uniprot.org/gene3d/3.30.260.10
type: Resource
database: Gene3D
comment: TCP-1-like chaperonin intermediate domain
signature sequence match: Gene3D 3.30.260.10 match 1

MF_00600
type: Resource
database: HAMAP
comment: CH60
signature sequence match: HAMAP MF 00600 match 1

IPR018370
type: Resource
database: InterPro
comment: Chaperonin_Cpn60_CS

IPR001844
type: Resource
database: InterPro
comment: Cpn60/GroEL

IPR002423
type: Resource
database: InterPro
comment: Cpn60/GroEL/TCP-1

IPR027409
type: Resource
database: InterPro
comment: GroEL-like_apical_dom_sf

IPR027413
type: Resource
database: InterPro
comment: GROEL-like_equatorial_sf

IPR027410
type: Resource
database: InterPro
comment: TCP-1-like_intermed_sf

TIGR02348
type: Resource
database: NCBIfam
comment: GroEL
signature sequence match: NCBIfam TIGR02348 match 1

PTHR45633
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633 match 1

PTHR45633:SF3
type: Resource
database: PANTHER
comment: 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR45633:SF3 match 1

PF00118
type: Resource
database: Pfam
comment: Cpn60_TCP1
signature sequence match: Pfam PF00118 match 1

PR00298
type: Resource
database: PRINTS
comment: CHAPERONIN60

SSF52029
type: Resource
database: SUPFAM
comment: GroEL apical domain-like
signature sequence match: SUPFAM SSF52029 match 1

SSF48592
type: Resource
database: SUPFAM
comment: GroEL equatorial domain-like
signature sequence match: SUPFAM SSF48592 match 1

SSF54849
type: Resource
database: SUPFAM
comment: GroEL-intermediate domain like
signature sequence match: SUPFAM SSF54849 match 1

PS00296
type: Resource
database: PROSITE
comment: CHAPERONINS_CPN60
signature sequence match: PROSITE PS00296 match 1

SIPF255B4347D4E348A
type: Structured Name
full name: Chaperonin GroEL
ec name: 5.6.1.7

SIPE5C33196A30979CA
type: Structured Name
full name: 60 kDa chaperonin

SIPE325E657B082D974
type: Structured Name
full name: Chaperonin-60
short name: Cpn60

groEL
type: Gene
alternative label: groL
locus name: Bd0099

SIP1C8CA1D28E38E934
type: Function Annotation
comment: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

SIP74E49C31A7580F2C
type: Subunit Annotation
comment: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.

SIPB63F48F99CD9A3B4
type: Similarity Annotation
comment: Belongs to the chaperonin (HSP60) family.

PRO_0000063285
type: Chain Annotation
comment: Chaperonin GroEL
mass: 58128
range: 22859178834473262tt1tt546

22859178834473262tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRI1-1

22859178834473262tt546
type: Position
type: ExactPosition
position: 546
reference: Q6MRI1-1

SIPC1CF96858DC3FAB4
type: Region Annotation
comment: Disordered
range: 22859178834473262tt525tt546

22859178834473262tt525
type: Position
type: ExactPosition
position: 525
reference: Q6MRI1-1

22859178834473262tt29
type: Position
type: ExactPosition
position: 29
reference: Q6MRI1-1

22859178834473262tt32
type: Position
type: ExactPosition
position: 32
reference: Q6MRI1-1

22859178834473262tt50
type: Position
type: ExactPosition
position: 50
reference: Q6MRI1-1

22859178834473262tt86
type: Position
type: ExactPosition
position: 86
reference: Q6MRI1-1

22859178834473262tt90
type: Position
type: ExactPosition
position: 90
reference: Q6MRI1-1

22859178834473262tt414
type: Position
type: ExactPosition
position: 414
reference: Q6MRI1-1

22859178834473262tt494
type: Position
type: ExactPosition
position: 494
reference: Q6MRI1-1

Q6MRI1-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 58128
value: MSKVITFSEDARTHILKGVNTLANAVKVTLGPKGRNVVIDKSFGSPLITKDGVTVAKEIELENKFENMGAQMVKEVASKTNDEAGDGTTTATVLAQAIYREGAKLVSAGHNPMSIKRGIDKAVGIIIEELKSMSKPVKGSNEVAQVGAISANNDKEIGQMLADAMDKVGREGVITIEESKTAKTEVTVVEGMQFDRGYLSPYFVTNAERMEAVLENAYVLVYDKKISSMKDMIGILEGVAKQGRQLLIIAEDVEGEALATLVVNKLRGTLHIAAVKAPGFGDRRKAMLEDIAILTGAKVISEDVGLKLEAATVADLGVAKRIVVDKDNTTIIDGAGKKNDINGRVGQIKAQIEETSSDYDKEKLKERLAKLAGGVAVIHVGAPSEVEMKEKKHRVEDALNATRAAVEEGIVAGGGTALLRASTKIDKSKFSEEEQFGATIIKRACEEPIRQIAANAGLDGAIVLDRILQNKSTTWGFNAYSDEYTDLIKDGVIDPVKVVRCALTNAASVSSLMLTTETMIAEAPKKESAAPAMPGHDGMGGMGGMM

http://purl.uniprot.org/uniprot/Q6MRI1#attribution-2F1A0E67B478851653C1AADDD6958B54
manual: true
evidence: ECO_0000255
source: MF_00600

P62635
type: Protein
reviewed: true
created: 2004-07-19
modified: 2023-09-13
version: 104
mnemonic: CHEB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPC2FD41740D06FCF7
enzyme: http://purl.uniprot.org/enzyme/3.1.1.61
enzyme: http://purl.uniprot.org/enzyme/3.5.1.44
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPD5371C9E6E0415A8
annotation: SIP6BECBC8E585A6869
annotation: SIPAF2EF1112FC64568
annotation: SIPF031A3839A2AE4EE
annotation: SIPFDF0D452BD1B133E
annotation: SIP7EFF9E7190DC2987
annotation: SIPEE4C8E09BD7C67BB
annotation: PRO_0000157977
annotation: SIP38273FF86ECB9DD5
annotation: SIP8EAFCE2C5BA6D4C2
annotation: SIP6507D71CF5432B16
annotation: SIP8B89A88160C1196A
annotation: SIP824C59D65FF14050
annotation: SIP3D91FC8572E74824
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/145
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0000156
classified with: GO_0008984
classified with: GO_0050568
classified with: GO_0006935
classified with: GO_0018277
classified with: GO_0006482
sequence: P62635-1
proteome: Chromosome

P62635-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG2201
type: Resource
database: eggNOG
comment: Bacteria

cd16432
type: Resource
database: CDD
comment: CheB_Rec
signature sequence match: CDD cd16432 match 1

cd17541
type: Resource
database: CDD
comment: REC_CheB-like
signature sequence match: CDD cd17541 match 1

http://purl.uniprot.org/gene3d/3.40.50.180
type: Resource
database: Gene3D
comment: Methylesterase CheB, C-terminal domain
signature sequence match: Gene3D 3.40.50.180 match 1

MF_00099
type: Resource
database: HAMAP
comment: CheB_chemtxs
signature sequence match: HAMAP MF 00099 match 1

IPR008248
type: Resource
database: InterPro
comment: CheB-like

IPR035909
type: Resource
database: InterPro
comment: CheB_C

IPR011006
type: Resource
database: InterPro
comment: CheY-like_superfamily

IPR000673
type: Resource
database: InterPro
comment: Sig_transdc_resp-reg_Me-estase

IPR001789
type: Resource
database: InterPro
comment: Sig_transdc_resp-reg_receiver

PTHR42872
type: Resource
database: PANTHER
comment: PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE
signature sequence match: PANTHER PTHR42872 match 1

PTHR42872:SF6
type: Resource
database: PANTHER
comment: PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE
signature sequence match: PANTHER PTHR42872:SF6 match 1

PF01339
type: Resource
database: Pfam
comment: CheB_methylest
signature sequence match: Pfam PF01339 match 1

PF00072
type: Resource
database: Pfam
comment: Response_reg
signature sequence match: Pfam PF00072 match 1

PIRSF000876
type: Resource
database: PIRSF
comment: RR_chemtxs_CheB
signature sequence match: PIRSF PIRSF000876 match 1

SM00448
type: Resource
database: SMART
comment: REC
signature sequence match: SMART SM00448 match 1

SSF52172
type: Resource
database: SUPFAM
comment: CheY-like
signature sequence match: SUPFAM SSF52172 match 1

SSF52738
type: Resource
database: SUPFAM
comment: Methylesterase CheB, C-terminal domain
signature sequence match: SUPFAM SSF52738 match 1

PS50122
type: Resource
database: PROSITE
comment: CHEB
signature sequence match: PROSITE PS50122 match 1

PS50110
type: Resource
database: PROSITE
comment: RESPONSE_REGULATORY
signature sequence match: PROSITE PS50110 match 1

SIPC2FD41740D06FCF7
type: Structured Name
full name: Protein-glutamate methylesterase/protein-glutamine glutaminase
ec name: 3.1.1.61
ec name: 3.5.1.44

cheB
type: Gene
locus name: Bd3467

SIPD5371C9E6E0415A8
type: Function Annotation
comment: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.

SIPFDF0D452BD1B133E
type: Domain Annotation
comment: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.

SIP7EFF9E7190DC2987
type: PTM Annotation
comment: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

SIPEE4C8E09BD7C67BB
type: Similarity Annotation
comment: Belongs to the CheB family.

PRO_0000157977
type: Chain Annotation
comment: Protein-glutamate methylesterase/protein-glutamine glutaminase
mass: 37850
range: 22577587422442798tt1tt354

22577587422442798tt1
type: Position
type: ExactPosition
position: 1
reference: P62635-1

22577587422442798tt354
type: Position
type: ExactPosition
position: 354
reference: P62635-1

SIP38273FF86ECB9DD5
type: Domain Extent Annotation
comment: Response regulatory
range: 22577587422442798tt6tt123

22577587422442798tt6
type: Position
type: ExactPosition
position: 6
reference: P62635-1

22577587422442798tt123
type: Position
type: ExactPosition
position: 123
reference: P62635-1

SIP8EAFCE2C5BA6D4C2
type: Domain Extent Annotation
comment: CheB-type methylesterase
range: 22577587422442798tt159tt351

22577587422442798tt159
type: Position
type: ExactPosition
position: 159
reference: P62635-1

22577587422442798tt351
type: Position
type: ExactPosition
position: 351
reference: P62635-1

22577587422442798tt171
type: Position
type: ExactPosition
position: 171
reference: P62635-1

22577587422442798tt197
type: Position
type: ExactPosition
position: 197
reference: P62635-1

22577587422442798tt293
type: Position
type: ExactPosition
position: 293
reference: P62635-1

SIP3D91FC8572E74824
type: Modified Residue Annotation
comment: 4-aspartylphosphate
range: 22577587422442798tt57tt57

22577587422442798tt57
type: Position
type: ExactPosition
position: 57
reference: P62635-1

P62635-1
type: Simple Sequence
modified: 2004-07-19
version: 1
mass: 37850
value: MAQKIRVLIVDDSAVIRKLLEKIFSSCADIEVVGTASDPYIARDKLVALKPDVMTLDVEMPRMDGISFLEKVMQHFPTRTIIFSSLAKTGSETYLRALEAGAIEIMEKPSIDVSQSLETLSAAIIEKVKAVAKARINPIKAVVPNPGAPVQKVASTSLARTTHQLLAVASSTGGTEALKVFLSGMPADIPGTLVVQHMPPGFTKSFAENLDKMFPFEVKEAQEGDQVVPGRVLIAPGNYHMEITRSGAFYYVKLHQGPALHSVRPAADYLMKSVAKYVGKNAMGVVLTGMGKDGAEGLLEMKNAGAYTVAQNEETCVVYGMPAAAVALGAADKVLPLDRIAGDLLKQLQTRNAA

http://purl.uniprot.org/uniprot/P62635#attribution-DCF38AE867D8117CED0A8252FB7D8B1F
manual: true
evidence: ECO_0000255
source: MF_00099

Q6MJE9
type: Protein
reviewed: true
created: 2006-10-03
modified: 2023-06-28
version: 80
mnemonic: CHED_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP09432520403E9A8D
enzyme: http://purl.uniprot.org/enzyme/3.5.1.44
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPF83E96B5A7223B1C
annotation: SIPC0B86720949BF60B
annotation: SIPED01CA11FCB824DE
annotation: PRO_0000251005
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/145
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0050568
classified with: GO_0006935
sequence: MLPVEHHVRIGQILIAENGEVLKTVLGSCVGIALVWRRQNKWALAHCLLPYPETFKEDKEARYVSQTIPRMLERMGATMADVSELEAIVAGGGRMMDGDKNYIKFVVGDENLKAAKAVLEKHRIRIVAFEPGGEQGTKMRIAGDGDYSIEKLPKTA
proteome: Chromosome

Q6MJE9-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1871
type: Resource
database: eggNOG
comment: Bacteria

cd16352
type: Resource
database: CDD
comment: CheD
signature sequence match: CDD cd16352 match 1

MF_01440
type: Resource
database: HAMAP
comment: CheD
signature sequence match: HAMAP MF 01440 match 1

IPR038592
type: Resource
database: InterPro
comment: CheD-like_sf

IPR005659
type: Resource
database: InterPro
comment: Chemorcpt_Glu_NH3ase_CheD

IPR011324
type: Resource
database: InterPro
comment: Cytotoxic_necrot_fac-like_cat

PTHR35147:SF1
type: Resource
database: PANTHER
comment: CHEMORECEPTOR GLUTAMINE DEAMIDASE CHED
signature sequence match: PANTHER PTHR35147:SF1 match 1

PTHR35147
type: Resource
database: PANTHER
comment: CHEMORECEPTOR GLUTAMINE DEAMIDASE CHED-RELATED
signature sequence match: PANTHER PTHR35147 match 1

PF03975
type: Resource
database: Pfam
comment: CheD
signature sequence match: Pfam PF03975 match 1

SSF64438
type: Resource
database: SUPFAM
comment: CNF1/YfiH-like putative cysteine hydrolases
signature sequence match: SUPFAM SSF64438 match 1

SIP09432520403E9A8D
type: Structured Name
full name: Probable chemoreceptor glutamine deamidase CheD
ec name: 3.5.1.44

cheD
type: Gene
locus name: Bd2829

SIPF83E96B5A7223B1C
type: Function Annotation
comment: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

SIPED01CA11FCB824DE
type: Similarity Annotation
comment: Belongs to the CheD family.

PRO_0000251005
type: Chain Annotation
comment: Probable chemoreceptor glutamine deamidase CheD
mass: 17304
range: 22859178699995438tt1tt156

22859178699995438tt1
type: Position
type: ExactPosition
position: 1
reference: MLPVEHHVRIGQILIAENGEVLKTVLGSCVGIALVWRRQNKWALAHCLLPYPETFKEDKEARYVSQTIPRMLERMGATMADVSELEAIVAGGGRMMDGDKNYIKFVVGDENLKAAKAVLEKHRIRIVAFEPGGEQGTKMRIAGDGDYSIEKLPKTA

22859178699995438tt156
type: Position
type: ExactPosition
position: 156
reference: MLPVEHHVRIGQILIAENGEVLKTVLGSCVGIALVWRRQNKWALAHCLLPYPETFKEDKEARYVSQTIPRMLERMGATMADVSELEAIVAGGGRMMDGDKNYIKFVVGDENLKAAKAVLEKHRIRIVAFEPGGEQGTKMRIAGDGDYSIEKLPKTA

MLPVEHHVRIGQILIAENGEVLKTVLGSCVGIALVWRRQNKWALAHCLLPYPETFKEDKEARYVSQTIPRMLERMGATMADVSELEAIVAGGGRMMDGDKNYIKFVVGDENLKAAKAVLEKHRIRIVAFEPGGEQGTKMRIAGDGDYSIEKLPKTA
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 17304

http://purl.uniprot.org/uniprot/Q6MJE9#attribution-69BF0BDD6A6C6907FEF60A871BA46CDF
manual: true
evidence: ECO_0000255
source: MF_01440

Q6MIV0
type: Protein
reviewed: true
created: 2004-10-11
modified: 2023-09-13
version: 105
mnemonic: CLPB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP38C4ECF2E591A446
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP2345FA2256AD32D1
annotation: SIP523270A1F255D104
annotation: SIP16CA061B8F8119AF
annotation: SIP0E604B580024EA26
annotation: SIPA7BF613D97D08CA4
annotation: PRO_0000191093
annotation: SIP816EFE6B219EC09F
annotation: SIPF8EBC2887A6DD94D
annotation: SIP00D8D9D771DFC066
annotation: SIP753B9B2D2BBDEAA7
annotation: SIP9DD20869AE7FD795
annotation: SIP2BC3B20C8F0820AA
annotation: SIP68E622102CF5BC3C
annotation: SIP70788EF4AE659168
annotation: SIPEA3EB5E2E2793841
annotation: SIPD671A0A7ED54D308
annotation: SIP6EC4E8F28EA6DA21
annotation: SIPA4E0CBB725A69C0F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/175
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/346
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0042026
classified with: GO_0009408
sequence: Q6MIV0-1
proteome: Chromosome

Q6MIV0-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0542
type: Resource
database: eggNOG
comment: Bacteria

cd00009
type: Resource
database: CDD
comment: AAA
signature sequence match: CDD cd00009 match 1

cd19499
type: Resource
database: CDD
comment: RecA-like_ClpB_Hsp104-like
signature sequence match: CDD cd19499 match 1

http://purl.uniprot.org/gene3d/1.10.1780.10
type: Resource
database: Gene3D
comment: Clp, N-terminal domain
signature sequence match: Gene3D 1.10.1780.10 match 1

IPR003959
type: Resource
database: InterPro
comment: ATPase_AAA_core

IPR017730
type: Resource
database: InterPro
comment: Chaperonin_ClpB

IPR019489
type: Resource
database: InterPro
comment: Clp_ATPase_C

IPR036628
type: Resource
database: InterPro
comment: Clp_N_dom_sf

IPR004176
type: Resource
database: InterPro
comment: Clp_R_dom

IPR001270
type: Resource
database: InterPro
comment: ClpA/B

IPR018368
type: Resource
database: InterPro
comment: ClpA/B_CS1

IPR028299
type: Resource
database: InterPro
comment: ClpA/B_CS2

IPR041546
type: Resource
database: InterPro
comment: ClpA/ClpB_AAA_lid

TIGR03346
type: Resource
database: NCBIfam
comment: chaperone_ClpB
signature sequence match: NCBIfam TIGR03346 match 1

PTHR11638
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE
signature sequence match: PANTHER PTHR11638 match 1

PTHR11638:SF18
type: Resource
database: PANTHER
comment: HEAT SHOCK PROTEIN 104
signature sequence match: PANTHER PTHR11638:SF18 match 1

PF00004
type: Resource
database: Pfam
comment: AAA
signature sequence match: Pfam PF00004 match 1

PF07724
type: Resource
database: Pfam
comment: AAA_2
signature sequence match: Pfam PF07724 match 1

PF17871
type: Resource
database: Pfam
comment: AAA_lid_9
signature sequence match: Pfam PF17871 match 1

PF02861
type: Resource
database: Pfam
comment: Clp_N
signature sequence match: Pfam PF02861 match 1
signature sequence match: Pfam PF02861 match 2

PF10431
type: Resource
database: Pfam
comment: ClpB_D2-small
signature sequence match: Pfam PF10431 match 1

PR00300
type: Resource
database: PRINTS
comment: CLPPROTEASEA

SM01086
type: Resource
database: SMART
comment: ClpB_D2-small
signature sequence match: SMART SM01086 match 1

SSF81923
type: Resource
database: SUPFAM
comment: Double Clp-N motif
signature sequence match: SUPFAM SSF81923 match 1

PS51903
type: Resource
database: PROSITE
comment: CLP_R
signature sequence match: PROSITE PS51903 match 1

PS00870
type: Resource
database: PROSITE
comment: CLPAB_1
signature sequence match: PROSITE PS00870 match 1

PS00871
type: Resource
database: PROSITE
comment: CLPAB_2
signature sequence match: PROSITE PS00871 match 1

SIP38C4ECF2E591A446
type: Structured Name
full name: Chaperone protein ClpB

clpB
type: Gene
locus name: Bd3048

SIP2345FA2256AD32D1
type: Function Annotation
comment: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).

SIP523270A1F255D104
type: Subunit Annotation
comment: Homohexamer. The oligomerization is ATP-dependent (By similarity).

SIP0E604B580024EA26
type: Domain Annotation
comment: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

SIPA7BF613D97D08CA4
type: Similarity Annotation
comment: Belongs to the ClpA/ClpB family.

PRO_0000191093
type: Chain Annotation
comment: Chaperone protein ClpB
mass: 95239
range: 22859178684330030tt1tt855

22859178684330030tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MIV0-1

22859178684330030tt855
type: Position
type: ExactPosition
position: 855
reference: Q6MIV0-1

SIP816EFE6B219EC09F
type: Domain Extent Annotation
comment: Clp R
range: 22859178684330030tt1tt142

22859178684330030tt142
type: Position
type: ExactPosition
position: 142
reference: Q6MIV0-1

SIPF8EBC2887A6DD94D
type: Region Annotation
comment: Repeat 1
range: 22859178684330030tt1tt66

22859178684330030tt66
type: Position
type: ExactPosition
position: 66
reference: Q6MIV0-1

SIP00D8D9D771DFC066
type: Region Annotation
comment: Disordered
range: 22859178684330030tt1tt22

22859178684330030tt22
type: Position
type: ExactPosition
position: 22
reference: Q6MIV0-1

SIP753B9B2D2BBDEAA7
type: Region Annotation
comment: Repeat 2
range: 22859178684330030tt78tt142

22859178684330030tt78
type: Position
type: ExactPosition
position: 78
reference: Q6MIV0-1

SIP9DD20869AE7FD795
type: Region Annotation
comment: NBD1
range: 22859178684330030tt155tt336

22859178684330030tt155
type: Position
type: ExactPosition
position: 155
reference: Q6MIV0-1

22859178684330030tt336
type: Position
type: ExactPosition
position: 336
reference: Q6MIV0-1

SIP2BC3B20C8F0820AA
type: Region Annotation
comment: Linker
range: 22859178684330030tt337tt547

22859178684330030tt337
type: Position
type: ExactPosition
position: 337
reference: Q6MIV0-1

22859178684330030tt547
type: Position
type: ExactPosition
position: 547
reference: Q6MIV0-1

SIP68E622102CF5BC3C
type: Region Annotation
comment: Disordered
range: 22859178684330030tt513tt532

22859178684330030tt513
type: Position
type: ExactPosition
position: 513
reference: Q6MIV0-1

22859178684330030tt532
type: Position
type: ExactPosition
position: 532
reference: Q6MIV0-1

SIP70788EF4AE659168
type: Region Annotation
comment: NBD2
range: 22859178684330030tt557tt765

22859178684330030tt557
type: Position
type: ExactPosition
position: 557
reference: Q6MIV0-1

22859178684330030tt765
type: Position
type: ExactPosition
position: 765
reference: Q6MIV0-1

SIPEA3EB5E2E2793841
type: Region Annotation
comment: C-terminal
range: 22859178684330030tt766tt855

22859178684330030tt766
type: Position
type: ExactPosition
position: 766
reference: Q6MIV0-1

22859178684330030tt387
type: Position
type: ExactPosition
position: 387
reference: Q6MIV0-1

22859178684330030tt521
type: Position
type: ExactPosition
position: 521
reference: Q6MIV0-1

22859178684330030tt202
type: Position
type: ExactPosition
position: 202
reference: Q6MIV0-1

22859178684330030tt209
type: Position
type: ExactPosition
position: 209
reference: Q6MIV0-1

22859178684330030tt607
type: Position
type: ExactPosition
position: 607
reference: Q6MIV0-1

22859178684330030tt614
type: Position
type: ExactPosition
position: 614
reference: Q6MIV0-1

1
subclass of: CHEBI_30616

2
subclass of: CHEBI_30616

Q6MIV0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 95239
value: MTRKSQEAMQAAARLAERKSSPSVEPEHLLMELVQQTEGIVPRILDKLNVPQAQFLAELRTKIDKFPQVTGGGQKMFASPRLEKIFQAAETEAQEWGDSYISTEHFFMAMLKGGDSELNGLFKKNKVTAEAARTALTEIRGKQKVTDDDPENKYEVLNKYARDLTALAAEGKLDPVVGRDEEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIIKQDVPDNLIGKKLMSLDMGALIAGAKYRGEFEDRLKAVIKEVTSSDGQIILFIDELHTLVGAGKTEGAMDAGQLLKPALARGELRCIGATTLDEYRKYIEKDAALERRFQTVMVEEPSVEDAITILRGLKEKYEVHHGIRITDAALVSAVKLSHRYITNRFLPDKAIDLIDEAASKLGIETRSVPEEVDKIERELMQLRIEKEALKKEKDESARERLAVIDKEITELNAKNQLLREQWEFEKGGIEGIKKLKADIEDLKVAVAKAEREGDLGKAAELKYGKLPEAEKKLKALEERSKEGAKSSSENRMLKEEVGPEDVAEVVAKWTGIPVSKMLESESQKLLHMEDSLKHRVVGQDHALTIVADAIRRARAEISDPNRPIGTFMFLGPTGVGKTETVKALAEFLFDDEQAVVRIDMSEYMEKHAVSRLIGAPPGYVGYEEGGQLTESVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVLIMTSNVGSQSILDPGMSENQKREAVNEALRERFRPEFLNRIDEIVMFKSLGEAQISGIVKVQLDLVAQRLRAKKIGIDFNQEAIDFLAKKGYDPIYGARPLKRVIQTELLNPLSKEIISGKVKAGDTIHVKANGSTLTF

http://purl.uniprot.org/uniprot/Q6MIV0#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q6MIV0#attribution-E711A519A93D37BE424291FA19F65320
manual: true
evidence: ECO_0000255
source: PRU01251

http://purl.uniprot.org/uniprot/Q6MIV0#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6MH11
type: Protein
reviewed: true
created: 2005-03-01
modified: 2023-06-28
version: 106
mnemonic: CLPP_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP07EC96E90BC5B0F2
alternative name: SIP7353D1C153228504
enzyme: http://purl.uniprot.org/enzyme/3.4.21.92
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP77CA4DE2F4CAFD39
annotation: SIP048DC294981D6DC3
annotation: SIP0C596689E2DFD4FD
annotation: SIPD609193C2D20194C
annotation: SIP270B64137BD8D58E
annotation: PRO_0000179505
annotation: SIPF9D0823A963144F7
annotation: SIP070C516D887610DC
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/720
classified with: GO_0005737
classified with: GO_0004176
classified with: GO_0004252
classified with: GO_0006508
sequence: Q6MH11-1
proteome: Chromosome

Q6MH11-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0740
type: Resource
database: eggNOG
comment: Bacteria

cd07017
type: Resource
database: CDD
comment: S14_ClpP_2
signature sequence match: CDD cd07017 match 1

MF_00444
type: Resource
database: HAMAP
comment: ClpP
signature sequence match: HAMAP MF 00444 match 1

IPR001907
type: Resource
database: InterPro
comment: ClpP

IPR029045
type: Resource
database: InterPro
comment: ClpP/crotonase-like_dom_sf

IPR023562
type: Resource
database: InterPro
comment: ClpP/TepA

IPR033135
type: Resource
database: InterPro
comment: ClpP_His_AS

IPR018215
type: Resource
database: InterPro
comment: ClpP_Ser_AS

PTHR10381
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT
signature sequence match: PANTHER PTHR10381 match 1

PTHR10381:SF11
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL
signature sequence match: PANTHER PTHR10381:SF11 match 1

PF00574
type: Resource
database: Pfam
comment: CLP_protease
signature sequence match: Pfam PF00574 match 1

PR00127
type: Resource
database: PRINTS
comment: CLPPROTEASEP

SSF52096
type: Resource
database: SUPFAM
comment: ClpP/crotonase
signature sequence match: SUPFAM SSF52096 match 1

PS00382
type: Resource
database: PROSITE
comment: CLP_PROTEASE_HIS
signature sequence match: PROSITE PS00382 match 1

PS00381
type: Resource
database: PROSITE
comment: CLP_PROTEASE_SER
signature sequence match: PROSITE PS00381 match 1

SIP07EC96E90BC5B0F2
type: Structured Name
full name: ATP-dependent Clp protease proteolytic subunit
ec name: 3.4.21.92

SIP7353D1C153228504
type: Structured Name
full name: Endopeptidase Clp

clpP
type: Gene
locus name: Bd3754

SIP77CA4DE2F4CAFD39
type: Function Annotation
comment: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.

SIP0C596689E2DFD4FD
type: Subunit Annotation
comment: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIP270B64137BD8D58E
type: Similarity Annotation
comment: Belongs to the peptidase S14 family.

PRO_0000179505
type: Chain Annotation
comment: ATP-dependent Clp protease proteolytic subunit
mass: 23524
range: 22859178665128238tt1tt212

22859178665128238tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MH11-1

22859178665128238tt212
type: Position
type: ExactPosition
position: 212
reference: Q6MH11-1

SIPF9D0823A963144F7
type: Active Site Annotation
comment: Nucleophile
range: 22859178665128238tt109tt109

22859178665128238tt109
type: Position
type: ExactPosition
position: 109
reference: Q6MH11-1

22859178665128238tt134
type: Position
type: ExactPosition
position: 134
reference: Q6MH11-1

Q6MH11-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 23524
value: MTPQSQPQETAVALIPYVIEQTSKGERSYDIYSRLLKDRIIILGTAVTDEVANSIIAQMLFLEVDNPEKPIHLYINSPGGSVSAGLAIYDFMQFVKCDVATYCMGMAASMGSLLLTAGTKGMRYSLPNTRIMIHQPLLSGGGLSGQVTDIEIHAKELVKTKEKLTRIYETHTGRDYDTLRAAMERDNFMDPYQAKEFGLLDHVVESRKAKKG

http://purl.uniprot.org/uniprot/Q6MH11#attribution-83FF83956DB918F871897D2ABDA0D60B
manual: true
evidence: ECO_0000255
source: MF_00444

Q6MNG7
type: Protein
reviewed: true
created: 2005-06-07
modified: 2023-06-28
version: 88
mnemonic: CLPS_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP8FB72E27D81FBA75
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP4F1DE6E764C3635F
annotation: SIP620A0186F57EAE8C
annotation: SIP0D6BF17D7C62DC4E
annotation: PRO_0000215686
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0030163
classified with: GO_0006508
sequence: MGNNKKDSNSNYPFASPEGEAGVQLVPKLDTPKMYKVILLNDDYTPMDFVVLVLRRFFAKTEEQATEIMLDVHKKGAGVAGVFSLEIAEMKVMQVNQFAQLNQYPLKSTLEEEA
proteome: Chromosome

Q6MNG7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG2127
type: Resource
database: eggNOG
comment: Bacteria

MF_00302
type: Resource
database: HAMAP
comment: ClpS
signature sequence match: HAMAP MF 00302 match 1

IPR022935
type: Resource
database: InterPro
comment: ClpS

IPR003769
type: Resource
database: InterPro
comment: ClpS_core

IPR014719
type: Resource
database: InterPro
comment: Ribosomal_L7/12_C/ClpS-like

PTHR33473:SF19
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS
signature sequence match: PANTHER PTHR33473:SF19 match 1

PTHR33473
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS1, CHLOROPLASTIC
signature sequence match: PANTHER PTHR33473 match 1

PF02617
type: Resource
database: Pfam
comment: ClpS
signature sequence match: Pfam PF02617 match 1

SSF54736
type: Resource
database: SUPFAM
comment: ClpS-like
signature sequence match: SUPFAM SSF54736 match 1

SIP8FB72E27D81FBA75
type: Structured Name
full name: ATP-dependent Clp protease adapter protein ClpS

clpS
type: Gene
locus name: Bd1289

SIP4F1DE6E764C3635F
type: Function Annotation
comment: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

SIP620A0186F57EAE8C
type: Subunit Annotation
comment: Binds to the N-terminal domain of the chaperone ClpA.

SIP0D6BF17D7C62DC4E
type: Similarity Annotation
comment: Belongs to the ClpS family.

PRO_0000215686
type: Chain Annotation
comment: ATP-dependent Clp protease adapter protein ClpS
mass: 12802
range: 22859178767234862tt1tt114

22859178767234862tt1
type: Position
type: ExactPosition
position: 1
reference: MGNNKKDSNSNYPFASPEGEAGVQLVPKLDTPKMYKVILLNDDYTPMDFVVLVLRRFFAKTEEQATEIMLDVHKKGAGVAGVFSLEIAEMKVMQVNQFAQLNQYPLKSTLEEEA

22859178767234862tt114
type: Position
type: ExactPosition
position: 114
reference: MGNNKKDSNSNYPFASPEGEAGVQLVPKLDTPKMYKVILLNDDYTPMDFVVLVLRRFFAKTEEQATEIMLDVHKKGAGVAGVFSLEIAEMKVMQVNQFAQLNQYPLKSTLEEEA

MGNNKKDSNSNYPFASPEGEAGVQLVPKLDTPKMYKVILLNDDYTPMDFVVLVLRRFFAKTEEQATEIMLDVHKKGAGVAGVFSLEIAEMKVMQVNQFAQLNQYPLKSTLEEEA
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 12802

http://purl.uniprot.org/uniprot/Q6MNG7#attribution-3174D9D7CFB4D426EA95BE9E06ACC2E0
manual: true
evidence: ECO_0000255
source: MF_00302

Q6MH12
type: Protein
reviewed: true
created: 2005-03-15
modified: 2023-09-13
version: 106
mnemonic: CLPX_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPF43CC31C6B90A8EC
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPC5A1FBC38B1BAB41
annotation: SIP28D15E43E0A674A4
annotation: SIP9287E473E90EECF1
annotation: PRO_0000160317
annotation: SIP5F9547A97FBF47BE
annotation: SIP60AC855A46D443CA
annotation: SIP1E0B23665E491C09
annotation: SIP075031719ABEC4E3
annotation: SIPE73008A0DF6FAA95
annotation: SIPDCBEC8D195DD9BD8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0140662
classified with: GO_0046983
classified with: GO_0051082
classified with: GO_0008270
sequence: Q6MH12-1
proteome: Chromosome

Q6MH12-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1219
type: Resource
database: eggNOG
comment: Bacteria

cd19497
type: Resource
database: CDD
comment: RecA-like_ClpX
signature sequence match: CDD cd19497 match 1

http://purl.uniprot.org/gene3d/6.20.220.10
type: Resource
database: Gene3D
comment: ClpX chaperone, C4-type zinc finger domain
signature sequence match: Gene3D 6.20.220.10 match 1

MF_00175
type: Resource
database: HAMAP
comment: ClpX
signature sequence match: HAMAP MF 00175 match 1

IPR004487
type: Resource
database: InterPro
comment: Clp_protease_ATP-bd_su_ClpX

IPR046425
type: Resource
database: InterPro
comment: ClpX_bact

IPR010603
type: Resource
database: InterPro
comment: Znf_CppX_C4

IPR038366
type: Resource
database: InterPro
comment: Znf_CppX_C4_sf

TIGR00382
type: Resource
database: NCBIfam
comment: clpX
signature sequence match: NCBIfam TIGR00382 match 1

PTHR48102:SF7
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR48102:SF7 match 1

PTHR48102
type: Resource
database: PANTHER
comment: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED
signature sequence match: PANTHER PTHR48102 match 1

PF06689
type: Resource
database: Pfam
comment: zf-C4_ClpX
signature sequence match: Pfam PF06689 match 1

SM00994
type: Resource
database: SMART
comment: zf-C4_ClpX
signature sequence match: SMART SM00994 match 1

SSF57716
type: Resource
database: SUPFAM
comment: Glucocorticoid receptor-like (DNA-binding domain)
signature sequence match: SUPFAM SSF57716 match 1

PS51902
type: Resource
database: PROSITE
comment: CLPX_ZB
signature sequence match: PROSITE PS51902 match 1

SIPF43CC31C6B90A8EC
type: Structured Name
full name: ATP-dependent Clp protease ATP-binding subunit ClpX

clpX
type: Gene
locus name: Bd3753

SIPC5A1FBC38B1BAB41
type: Function Annotation
comment: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.

SIP28D15E43E0A674A4
type: Subunit Annotation
comment: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

SIP9287E473E90EECF1
type: Similarity Annotation
comment: Belongs to the ClpX chaperone family.

PRO_0000160317
type: Chain Annotation
comment: ATP-dependent Clp protease ATP-binding subunit ClpX
mass: 47160
range: 22859178665128494tt1tt431

22859178665128494tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MH12-1

22859178665128494tt431
type: Position
type: ExactPosition
position: 431
reference: Q6MH12-1

SIP5F9547A97FBF47BE
type: Domain Extent Annotation
comment: ClpX-type ZB
range: 22859178665128494tt1tt53

22859178665128494tt53
type: Position
type: ExactPosition
position: 53
reference: Q6MH12-1

22859178665128494tt12
type: Position
type: ExactPosition
position: 12
reference: Q6MH12-1

22859178665128494tt15
type: Position
type: ExactPosition
position: 15
reference: Q6MH12-1

22859178665128494tt34
type: Position
type: ExactPosition
position: 34
reference: Q6MH12-1

22859178665128494tt37
type: Position
type: ExactPosition
position: 37
reference: Q6MH12-1

22859178665128494tt120
type: Position
type: ExactPosition
position: 120
reference: Q6MH12-1

22859178665128494tt127
type: Position
type: ExactPosition
position: 127
reference: Q6MH12-1

Q6MH12-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 47160
value: MTTKDTNGALRCSFCGKGQKEVKKLIAGPGVYICDECIDLCNDIIDEEKERETAVKGTFKVPKPSDIKTYLDDYVIGQTQAKKTLAVAVHNHYKRVNAMSGGKKSADVEMQKSNILLIGPTGSGKTLLAQTIAKVLNVPFAMADATTLTEAGYVGEDVENVVLNLLQASDYDVEKAQKGVIYVDEIDKISRKSENPSITRDVSGEGVQQALLKILEGTVANLPPKGGRKHPQQEFIQVDTTNILFIVGGAFVGLDKIIEQRTTNKTMGIAADIRTSEEVEKSANLLSKVEPDDLSKFGLIPEFIGRLPAIAVLAPLDEEALLDILVRPKNAITKQYQKLFSFEGVELKFTEKALRAVAQMALKRKTGARGLRGVLETAMLDVMYDIPSKNNVKEVVIDENVINEGAQPMLVYKTDEEIRAEEEEAKKKSSA

http://purl.uniprot.org/uniprot/Q6MH12#attribution-CFB06F30A19C652E3C2E44B930DCAAA4
manual: true
evidence: ECO_0000255
source: MF_00175

http://purl.uniprot.org/uniprot/Q6MH12#attribution-53EBA6D767FE97D40C9959E24A2E919D
manual: true
evidence: ECO_0000255
source: PRU01250

Q6MQ60
type: Protein
reviewed: true
created: 2005-03-15
modified: 2023-09-13
version: 104
mnemonic: COAD_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPF6F66FCD23803F87
alternative name: SIPCEC148E019BD360F
alternative name: SIP35682BD6712EB9F8
enzyme: http://purl.uniprot.org/enzyme/2.7.7.3
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP1C4E6D58DDA9A85C
annotation: SIPC8230BAB5B626EAE
annotation: SIP13990BAAEB98357C
annotation: SIPE695DB65BCAE73B3
annotation: SIPAB4FB1B82D6A760B
annotation: SIPAE758D74FA00DFB1
annotation: SIPA2EF514C190879B5
annotation: PRO_0000156174
annotation: SIP50D8371FDA7971FA
annotation: SIP9C1E4748C103B042
annotation: SIPDEEF579E87874443
annotation: SIPA2283F8C7C361753
annotation: SIPC7B70DA7B3B5EC84
annotation: SIPAD9BC06E4E2E5FB0
annotation: SIP6E83B3DB12403E63
annotation: SIP9D3C0224F25316F3
annotation: SIP569C19F5C9454B0B
annotation: SIP23D9034A28B0F3D7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/173
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0004595
classified with: GO_0015937
sequence: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
proteome: Chromosome

Q6MQ60-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0669
type: Resource
database: eggNOG
comment: Bacteria

cd02163
type: Resource
database: CDD
comment: PPAT
signature sequence match: CDD cd02163 match 1

http://purl.uniprot.org/gene3d/3.40.50.620
type: Resource
database: Gene3D
comment: HUPs
signature sequence match: Gene3D 3.40.50.620 match 1
signature sequence match: Gene3D 3.40.50.620 match 2

MF_00151
type: Resource
database: HAMAP
comment: PPAT_bact
signature sequence match: HAMAP MF 00151 match 1

IPR004821
type: Resource
database: InterPro
comment: Cyt_trans-like

IPR001980
type: Resource
database: InterPro
comment: PPAT

IPR014729
type: Resource
database: InterPro
comment: Rossmann-like_a/b/a_fold

TIGR01510
type: Resource
database: NCBIfam
comment: coaD_prev_kdtB
signature sequence match: NCBIfam TIGR01510 match 1

TIGR00125
type: Resource
database: NCBIfam
comment: cyt_tran_rel
signature sequence match: NCBIfam TIGR00125 match 1

PTHR21342
type: Resource
database: PANTHER
comment: PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
signature sequence match: PANTHER PTHR21342 match 1

PTHR21342:SF1
type: Resource
database: PANTHER
comment: PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
signature sequence match: PANTHER PTHR21342:SF1 match 1

PF01467
type: Resource
database: Pfam
comment: CTP_transf_like
signature sequence match: Pfam PF01467 match 1

PR01020
type: Resource
database: PRINTS
comment: LPSBIOSNTHSS

SSF52374
type: Resource
database: SUPFAM
comment: Nucleotidylyl transferase
signature sequence match: SUPFAM SSF52374 match 1

SIPF6F66FCD23803F87
type: Structured Name
full name: Phosphopantetheine adenylyltransferase
ec name: 2.7.7.3

SIPCEC148E019BD360F
type: Structured Name
full name: Dephospho-CoA pyrophosphorylase

SIP35682BD6712EB9F8
type: Structured Name
full name: Pantetheine-phosphate adenylyltransferase
short name: PPAT

coaD
type: Gene
locus name: Bd0623

SIP1C4E6D58DDA9A85C
type: Function Annotation
comment: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

SIPAB4FB1B82D6A760B
type: Subunit Annotation
comment: Homohexamer.

SIPA2EF514C190879B5
type: Similarity Annotation
comment: Belongs to the bacterial CoaD family.

PRO_0000156174
type: Chain Annotation
comment: Phosphopantetheine adenylyltransferase
mass: 17890
range: 22859178816450606tt1tt160

22859178816450606tt1
type: Position
type: ExactPosition
position: 1
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt160
type: Position
type: ExactPosition
position: 160
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt10
type: Position
type: ExactPosition
position: 10
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt11
type: Position
type: ExactPosition
position: 11
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt18
type: Position
type: ExactPosition
position: 18
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt42
type: Position
type: ExactPosition
position: 42
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt74
type: Position
type: ExactPosition
position: 74
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt88
type: Position
type: ExactPosition
position: 88
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt89
type: Position
type: ExactPosition
position: 89
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt91
type: Position
type: ExactPosition
position: 91
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt99
type: Position
type: ExactPosition
position: 99
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt124
type: Position
type: ExactPosition
position: 124
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

22859178816450606tt130
type: Position
type: ExactPosition
position: 130
reference: MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK

SIP23D9034A28B0F3D7
type: Site Annotation
comment: Transition state stabilizer
range: 22859178816450606tt18tt18

substrate

MSKIAVYPGSFDPITMGHVDIINRISPLYDEVIVLVAQSSQKQSMFSVEERKTLIEKALSHLKNVKVDIFGGLTVEYMKKAKAQVIVRGLRAVSDFEYEMTMANMNRKLAPDFETLLVFASPEFYYISSRGVKEVAINGGALKGLVPDVVVEAMENKIRK
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 17890

http://purl.uniprot.org/uniprot/Q6MQ60#attribution-1FBF028CE5C20B3CECCC520D3E79044A
manual: true
evidence: ECO_0000255
source: MF_00151

Q6MIK8
type: Protein
reviewed: true
created: 2004-08-16
modified: 2023-09-13
version: 107
mnemonic: COAE_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP6C5CBBF5AA70C17E
alternative name: SIP7BD80E42975FEC74
enzyme: http://purl.uniprot.org/enzyme/2.7.1.24
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP98DCE4E027393BDA
annotation: SIPACD89BAA22B050C1
annotation: SIP5C9227DBE7997C0D
annotation: SIP546F17BB39B62121
annotation: SIP115F361278F83E33
annotation: PRO_0000172910
annotation: SIPF525DEB3C89EA553
annotation: SIP5EB4862915DCC412
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/173
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0004140
classified with: GO_0015937
classified with: GO_0016310
sequence: Q6MIK8-1
proteome: Chromosome

Q6MIK8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0237
type: Resource
database: eggNOG
comment: Bacteria

cd02022
type: Resource
database: CDD
comment: DPCK
signature sequence match: CDD cd02022 match 1

MF_00376
type: Resource
database: HAMAP
comment: Dephospho_CoA_kinase
signature sequence match: HAMAP MF 00376 match 1

IPR001977
type: Resource
database: InterPro
comment: Depp_CoAkinase

TIGR00152
type: Resource
database: NCBIfam
comment: dephospho-CoA kinase
signature sequence match: NCBIfam TIGR00152 match 1

PTHR10695:SF46
type: Resource
database: PANTHER
comment: BIFUNCTIONAL COENZYME A SYNTHASE-RELATED
signature sequence match: PANTHER PTHR10695:SF46 match 1

PTHR10695
type: Resource
database: PANTHER
comment: DEPHOSPHO-COA KINASE-RELATED
signature sequence match: PANTHER PTHR10695 match 1

PF01121
type: Resource
database: Pfam
comment: CoaE
signature sequence match: Pfam PF01121 match 1

PS51219
type: Resource
database: PROSITE
comment: DPCK
signature sequence match: PROSITE PS51219 match 1

SIP6C5CBBF5AA70C17E
type: Structured Name
full name: Dephospho-CoA kinase
ec name: 2.7.1.24

SIP7BD80E42975FEC74
type: Structured Name
full name: Dephosphocoenzyme A kinase

coaE
type: Gene
locus name: Bd3147

SIP98DCE4E027393BDA
type: Function Annotation
comment: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.

SIP115F361278F83E33
type: Similarity Annotation
comment: Belongs to the CoaE family.

PRO_0000172910
type: Chain Annotation
comment: Dephospho-CoA kinase
mass: 23343
range: 22859178683611182tt1tt201

22859178683611182tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MIK8-1

22859178683611182tt201
type: Position
type: ExactPosition
position: 201
reference: Q6MIK8-1

SIPF525DEB3C89EA553
type: Domain Extent Annotation
comment: DPCK
range: 22859178683611182tt3tt201

22859178683611182tt3
type: Position
type: ExactPosition
position: 3
reference: Q6MIK8-1

22859178683611182tt11
type: Position
type: ExactPosition
position: 11
reference: Q6MIK8-1

22859178683611182tt16
type: Position
type: ExactPosition
position: 16
reference: Q6MIK8-1

Q6MIK8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 23343
value: MKWIGLTGGIACGKSTVSRMLRTHDIPVVDADEIAKEVVKPGSAGLKSVIQEFGPEFLTADGALDRRKLGQKVFGHPELLHKLEAITHPLIREETRRRRRLYEDMGHKLAIYDIPLLFETRAKDQFDGVIVVACTKEQQKERLRRQNWSEDEIEMRIASQIPIQFKEQQADFVLHNNRDEQHLLREVDRVLKWLEELKNQN

http://purl.uniprot.org/uniprot/Q6MIK8#attribution-5BBABE863AC0B55418D957FE3499D9F3
manual: true
evidence: ECO_0000255
source: MF_00376

Q6MHI0
type: Protein
reviewed: true
created: 2006-12-12
modified: 2023-09-13
version: 104
mnemonic: COAX_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP9C2BC1CF6C19D180
alternative name: SIP5A689CF50805F96C
alternative name: SIP4F70A191848DB5A7
enzyme: http://purl.uniprot.org/enzyme/2.7.1.33
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP7DB90BC14693DBA4
annotation: SIP2E2DAF91B4213E6F
annotation: SIPE5BE34CBB88495F3
annotation: SIP8EA89569289AD7E2
annotation: SIP5553F5BE3BCDCA24
annotation: SIP7A64F46CA61B2F7E
annotation: SIP0B0FEE6F804008B2
annotation: PRO_0000267499
annotation: SIP4CE13E983F901F2C
annotation: SIPF018DF81ED75BAD1
annotation: SIPC97FBE2D6803C223
annotation: SIPE4E15D81BE9D8312
annotation: SIPFBC31B2C0BE5DA5D
annotation: SIPD237BABF64495C5B
annotation: SIP66A3CC7ECA9C37CD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/173
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/418
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/630
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0046872
classified with: GO_0004594
classified with: GO_0015937
classified with: GO_0016310
sequence: Q6MHI0-1
proteome: Chromosome

Q6MHI0-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1521
type: Resource
database: eggNOG
comment: Bacteria

cd00012
type: Resource
database: CDD
comment: NBD_sugar-kinase_HSP70_actin
signature sequence match: CDD cd00012 match 1

MF_01274
type: Resource
database: HAMAP
comment: Pantothen_kinase_3
signature sequence match: HAMAP MF 01274 match 1

IPR043129
type: Resource
database: InterPro
comment: ATPase_NBD

IPR004619
type: Resource
database: InterPro
comment: Type_III_PanK

TIGR00671
type: Resource
database: NCBIfam
comment: baf
signature sequence match: NCBIfam TIGR00671 match 1

PTHR34265
type: Resource
database: PANTHER
comment: TYPE III PANTOTHENATE KINASE
signature sequence match: PANTHER PTHR34265 match 1

PTHR34265:SF1
type: Resource
database: PANTHER
comment: TYPE III PANTOTHENATE KINASE
signature sequence match: PANTHER PTHR34265:SF1 match 1

PF03309
type: Resource
database: Pfam
comment: Pan_kinase
signature sequence match: Pfam PF03309 match 1

SSF53067
type: Resource
database: SUPFAM
comment: Actin-like ATPase domain
signature sequence match: SUPFAM SSF53067 match 1
signature sequence match: SUPFAM SSF53067 match 2

SIP9C2BC1CF6C19D180
type: Structured Name
full name: Type III pantothenate kinase
ec name: 2.7.1.33

SIP5A689CF50805F96C
type: Structured Name
full name: PanK-III

SIP4F70A191848DB5A7
type: Structured Name
full name: Pantothenic acid kinase

coaX
type: Gene
locus name: Bd3564

SIP7DB90BC14693DBA4
type: Function Annotation
comment: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

SIPE5BE34CBB88495F3
type: Cofactor Annotation
comment: A monovalent cation. Ammonium or potassium.
cofactor: CHEBI_28938
cofactor: CHEBI_29103

SIP5553F5BE3BCDCA24
type: Subunit Annotation
comment: Homodimer.

SIP0B0FEE6F804008B2
type: Similarity Annotation
comment: Belongs to the type III pantothenate kinase family.

PRO_0000267499
type: Chain Annotation
comment: Type III pantothenate kinase
mass: 27952
range: 22859178666700846tt1tt256

22859178666700846tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MHI0-1

22859178666700846tt256
type: Position
type: ExactPosition
position: 256
reference: Q6MHI0-1

SIP4CE13E983F901F2C
type: Active Site Annotation
comment: Proton acceptor
range: 22859178666700846tt109tt109

22859178666700846tt109
type: Position
type: ExactPosition
position: 109
reference: Q6MHI0-1

22859178666700846tt6
type: Position
type: ExactPosition
position: 6
reference: Q6MHI0-1

22859178666700846tt13
type: Position
type: ExactPosition
position: 13
reference: Q6MHI0-1

22859178666700846tt100
type: Position
type: ExactPosition
position: 100
reference: Q6MHI0-1

22859178666700846tt107
type: Position
type: ExactPosition
position: 107
reference: Q6MHI0-1

22859178666700846tt110
type: Position
type: ExactPosition
position: 110
reference: Q6MHI0-1

22859178666700846tt130
type: Position
type: ExactPosition
position: 130
reference: Q6MHI0-1

22859178666700846tt133
type: Position
type: ExactPosition
position: 133
reference: Q6MHI0-1

22859178666700846tt185
type: Position
type: ExactPosition
position: 185
reference: Q6MHI0-1

substrate

Q6MHI0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 27952
value: MILCLDVGNTQIYAGLFDKDKMVLSFRKNSKSGASSDETGIFLRTAIRENGFDPAKVKQIAICSVVPEVIYSLRGACMKYFNINPFILQAGVKTGLKIKYRNPLEVGADRIANSIAATHLHPGKNLILVDLGTATTFCAVSKDKDYLGGSIVAGLRLCMEALESKTAKLPSVEIVAMHEALGRATIESIQSGLYYGHLGTIKELTERITKECFQGERPMVIGTGGFSYLFEKEKVFDEIVPDLVLKGMLIALQHNA

http://purl.uniprot.org/uniprot/Q6MHI0#attribution-857E44A974A72E34E0B0BBCB2B0A8D28
manual: true
evidence: ECO_0000255
source: MF_01274

Q6MR11
type: Protein
reviewed: true
created: 2008-09-02
modified: 2023-09-13
version: 100
mnemonic: COXX_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP452E119B47F77DD2
alternative name: SIP3552FEA03CD0380A
alternative name: SIPA8C672D5C47B872B
enzyme: http://purl.uniprot.org/enzyme/2.5.1.141
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP9C4BC995B5DD507C
annotation: SIP84BDCA834DB0CED9
annotation: SIP137AF392B28C5ED5
annotation: SIPE6AC30A7F316F5C5
annotation: SIP28633FADCFC424D9
annotation: SIPFC9987E7F51FDBAE
annotation: PRO_0000346028
annotation: SIP1E0FA6E29036B692
annotation: SIP0F29FDDC6F00F868
annotation: SIP120BB89C71179215
annotation: SIPEC0022DA0797932E
annotation: SIP7FF3FF32FFE2C30D
annotation: SIP1DF8AB7FF7A35D36
annotation: SIPD995F2427F77CE74
annotation: SIPAB7B974E31E47110
annotation: SIP64085FFC2E7769A0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/350
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005886
classified with: GO_0008495
classified with: GO_0048034
sequence: Q6MR11-1
proteome: Chromosome

Q6MR11-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0109
type: Resource
database: eggNOG
comment: Bacteria

cd13957
type: Resource
database: CDD
comment: PT_UbiA_Cox10
signature sequence match: CDD cd13957 match 1

http://purl.uniprot.org/gene3d/1.10.357.140
type: Resource
database: Gene3D
comment: UbiA prenyltransferase
signature sequence match: Gene3D 1.10.357.140 match 1

MF_00154
type: Resource
database: HAMAP
comment: CyoE_CtaB
signature sequence match: HAMAP MF 00154 match 1

IPR006369
type: Resource
database: InterPro
comment: Protohaem_IX_farnesylTrfase

IPR000537
type: Resource
database: InterPro
comment: UbiA_prenyltransferase

IPR030470
type: Resource
database: InterPro
comment: UbiA_prenylTrfase_CS

IPR044878
type: Resource
database: InterPro
comment: UbiA_sf

TIGR01473
type: Resource
database: NCBIfam
comment: cyoE_ctaB
signature sequence match: NCBIfam TIGR01473 match 1

PTHR43448
type: Resource
database: PANTHER
comment: PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43448 match 1

PTHR43448:SF2
type: Resource
database: PANTHER
comment: PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43448:SF2 match 1

PF01040
type: Resource
database: Pfam
comment: UbiA
signature sequence match: Pfam PF01040 match 1

PS00943
type: Resource
database: PROSITE
comment: UBIA
signature sequence match: PROSITE PS00943 match 1

SIP452E119B47F77DD2
type: Structured Name
full name: Protoheme IX farnesyltransferase
ec name: 2.5.1.141

SIP3552FEA03CD0380A
type: Structured Name
full name: Heme B farnesyltransferase

SIPA8C672D5C47B872B
type: Structured Name
full name: Heme O synthase

ctaB
type: Gene
locus name: Bd0290

SIP9C4BC995B5DD507C
type: Function Annotation
comment: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

SIP28633FADCFC424D9
type: Annotation
comment: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.

SIPFC9987E7F51FDBAE
type: Similarity Annotation
comment: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.

PRO_0000346028
type: Chain Annotation
comment: Protoheme IX farnesyltransferase
mass: 33277
range: 22859178832900398tt1tt292

22859178832900398tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MR11-1

22859178832900398tt292
type: Position
type: ExactPosition
position: 292
reference: Q6MR11-1

SIP1E0FA6E29036B692
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt11tt31

22859178832900398tt11
type: Position
type: ExactPosition
position: 11
reference: Q6MR11-1

22859178832900398tt31
type: Position
type: ExactPosition
position: 31
reference: Q6MR11-1

SIP0F29FDDC6F00F868
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt37tt57

22859178832900398tt37
type: Position
type: ExactPosition
position: 37
reference: Q6MR11-1

22859178832900398tt57
type: Position
type: ExactPosition
position: 57
reference: Q6MR11-1

SIP120BB89C71179215
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt85tt105

22859178832900398tt85
type: Position
type: ExactPosition
position: 85
reference: Q6MR11-1

22859178832900398tt105
type: Position
type: ExactPosition
position: 105
reference: Q6MR11-1

SIPEC0022DA0797932E
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt108tt128

22859178832900398tt108
type: Position
type: ExactPosition
position: 108
reference: Q6MR11-1

22859178832900398tt128
type: Position
type: ExactPosition
position: 128
reference: Q6MR11-1

SIP7FF3FF32FFE2C30D
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt133tt153

22859178832900398tt133
type: Position
type: ExactPosition
position: 133
reference: Q6MR11-1

22859178832900398tt153
type: Position
type: ExactPosition
position: 153
reference: Q6MR11-1

SIP1DF8AB7FF7A35D36
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt163tt183

22859178832900398tt163
type: Position
type: ExactPosition
position: 163
reference: Q6MR11-1

22859178832900398tt183
type: Position
type: ExactPosition
position: 183
reference: Q6MR11-1

SIPD995F2427F77CE74
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt199tt219

22859178832900398tt199
type: Position
type: ExactPosition
position: 199
reference: Q6MR11-1

22859178832900398tt219
type: Position
type: ExactPosition
position: 219
reference: Q6MR11-1

SIPAB7B974E31E47110
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt223tt243

22859178832900398tt223
type: Position
type: ExactPosition
position: 223
reference: Q6MR11-1

22859178832900398tt243
type: Position
type: ExactPosition
position: 243
reference: Q6MR11-1

SIP64085FFC2E7769A0
type: Transmembrane Annotation
comment: Helical
range: 22859178832900398tt261tt281

22859178832900398tt261
type: Position
type: ExactPosition
position: 261
reference: Q6MR11-1

22859178832900398tt281
type: Position
type: ExactPosition
position: 281
reference: Q6MR11-1

Q6MR11-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 33277
value: MLRIYADLTKFGIVVFSVLAGLAGYATGFQIENPFDWKIFLETLLGIYFLSSGSLALNQVQDWKIDQKMPRTAKRPIPSGKIKPAAAGILSVGLLLVGMNMLFKLEPVAGWVGLFCVFLYNGPYTLWWKRRWVFAAVPGAIPGALPVTIGYAVANPDIFNSESLYLFLIMFLWQMPHFWVLAIRYKDDYAAGGIPTLPVALGMEKTMFQVGLYTLVYVGVALAAPMFVHASWMFVLLTFPFVFKVLQEFYRYYKSNGTERWLAFFMWLNVSMLVFIIIPVIDKWNFLFIHHN

http://purl.uniprot.org/uniprot/Q6MR11#attribution-26CE0E084B6FE50DE7CCBDB8C156B76E
manual: true
evidence: ECO_0000255
source: MF_00154

Q6MRM9
type: Protein
reviewed: true
created: 2008-05-20
modified: 2023-09-13
version: 106
mnemonic: DAPA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP3DCCD2FAF2A8502D
enzyme: http://purl.uniprot.org/enzyme/4.3.3.7
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP897B522DE270C5E0
annotation: SIPDED3014BB1894E37
annotation: SIP66E428E6B84BD295
annotation: SIPF6CC82BA731F5B69
annotation: SIPB858C8E6C77F8568
annotation: SIPD82D8D44355CDF6A
annotation: SIP4702CA6D79A8D864
annotation: PRO_1000080524
annotation: SIPDD80DE236CBC03B9
annotation: SIP2F62D2F48857A5CF
annotation: SIPA0E662D6F448CECC
annotation: SIP3E788702D921F68E
annotation: SIP1646CA8EB559443D
annotation: SIP9430F00ADA2DE4E1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0005737
classified with: GO_0008840
classified with: GO_0019877
classified with: GO_0009089
sequence: Q6MRM9-1
proteome: Chromosome

Q6MRM9-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0329
type: Resource
database: eggNOG
comment: Bacteria

cd00950
type: Resource
database: CDD
comment: DHDPS
signature sequence match: CDD cd00950 match 1

http://purl.uniprot.org/gene3d/3.20.20.70
type: Resource
database: Gene3D
comment: Aldolase class I
signature sequence match: Gene3D 3.20.20.70 match 1

MF_00418
type: Resource
database: HAMAP
comment: DapA
signature sequence match: HAMAP MF 00418 match 1

IPR013785
type: Resource
database: InterPro
comment: Aldolase_TIM

IPR005263
type: Resource
database: InterPro
comment: DapA

IPR002220
type: Resource
database: InterPro
comment: DapA-like

IPR020625
type: Resource
database: InterPro
comment: Schiff_base-form_aldolases_AS

TIGR00674
type: Resource
database: NCBIfam
comment: dapA
signature sequence match: NCBIfam TIGR00674 match 1

PTHR12128:SF66
type: Resource
database: PANTHER
comment: 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128:SF66 match 1

PTHR12128
type: Resource
database: PANTHER
comment: DIHYDRODIPICOLINATE SYNTHASE
signature sequence match: PANTHER PTHR12128 match 1

PF00701
type: Resource
database: Pfam
comment: DHDPS
signature sequence match: Pfam PF00701 match 1

PIRSF001365
type: Resource
database: PIRSF
comment: DHDPS
signature sequence match: PIRSF PIRSF001365 match 1

PR00146
type: Resource
database: PRINTS
comment: DHPICSNTHASE

SM01130
type: Resource
database: SMART
comment: DHDPS
signature sequence match: SMART SM01130 match 1

SSF51569
type: Resource
database: SUPFAM
comment: Aldolase
signature sequence match: SUPFAM SSF51569 match 1

PS00666
type: Resource
database: PROSITE
comment: DHDPS_2
signature sequence match: PROSITE PS00666 match 1

SIP3DCCD2FAF2A8502D
type: Structured Name
full name: 4-hydroxy-tetrahydrodipicolinate synthase
short name: HTPA synthase
ec name: 4.3.3.7

dapA
type: Gene
locus name: Bd0046

SIP897B522DE270C5E0
type: Function Annotation
comment: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

SIPF6CC82BA731F5B69
type: Subunit Annotation
comment: Homotetramer; dimer of dimers.

SIPD82D8D44355CDF6A
type: Similarity Annotation
comment: Belongs to the DapA family.

SIP4702CA6D79A8D864
type: Caution Annotation
comment: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

PRO_1000080524
type: Chain Annotation
comment: 4-hydroxy-tetrahydrodipicolinate synthase
mass: 31444
range: 22859178834737454tt1tt293

22859178834737454tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRM9-1

22859178834737454tt293
type: Position
type: ExactPosition
position: 293
reference: Q6MRM9-1

SIPDD80DE236CBC03B9
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22859178834737454tt134tt134

22859178834737454tt134
type: Position
type: ExactPosition
position: 134
reference: Q6MRM9-1

SIP2F62D2F48857A5CF
type: Active Site Annotation
comment: Schiff-base intermediate with substrate
range: 22859178834737454tt162tt162

22859178834737454tt162
type: Position
type: ExactPosition
position: 162
reference: Q6MRM9-1

22859178834737454tt46
type: Position
type: ExactPosition
position: 46
reference: Q6MRM9-1

22859178834737454tt204
type: Position
type: ExactPosition
position: 204
reference: Q6MRM9-1

SIP1646CA8EB559443D
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 22859178834737454tt45tt45

22859178834737454tt45
type: Position
type: ExactPosition
position: 45
reference: Q6MRM9-1

SIP9430F00ADA2DE4E1
type: Site Annotation
comment: Part of a proton relay during catalysis
range: 22859178834737454tt108tt108

22859178834737454tt108
type: Position
type: ExactPosition
position: 108
reference: Q6MRM9-1

Q6MRM9-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 31444
value: MKNFKGTFTALVTPFKNGKIDFASLDKLLKQQLAGGVDGFVVNGTTGESPVLTSSEKAELFKHIRNVCGDKVVLIMGTGSNNTAQTIEDSRKAEEMGADAILVVVPYYNKPPQRGLYEHFKAVASSVKIPTILYNVPGRTITSLETGTIRDLAKVKGVVGIKEATGKIDLASEIIKACGSEFVMLSGDDGTYVEFLGVGGHGVISVASHVIPAQMVQWKKWVSEGALDKARADIAKYNDLINLLFVEANPIPVKKALQLMGILESAELRLPLVELGAENTAKLQAEMKKVGVL

http://purl.uniprot.org/uniprot/Q6MRM9#attribution-BD5BACAA957515974E6FCCE76684BF01
manual: true
evidence: ECO_0000255
source: MF_00418

http://purl.uniprot.org/uniprot/Q6MRM9#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6MRM8
type: Protein
reviewed: true
created: 2006-03-21
modified: 2023-06-28
version: 111
mnemonic: DAPB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP889671A2F3EEDFCB
enzyme: http://purl.uniprot.org/enzyme/1.17.1.8
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPE021FA3BEC5E0E09
annotation: SIP7A54ACE682E73578
annotation: SIP63D20AA10AFB51C5
annotation: SIP499547C32DC61AF9
annotation: SIP57DBFCFDD9E8E525
annotation: SIP82A71C5D82AC780E
annotation: SIP710A2E40537634A0
annotation: PRO_0000228328
annotation: SIPAE2F2B4518AF0B47
annotation: SIPB94957CD18346935
annotation: SIP65B86CDDEBD0FF8D
annotation: SIP7F281671B669803A
annotation: SIPF4C73490EA90374C
annotation: SIP3FA38A10C0DD66D0
annotation: SIPD18F076191BD5CCA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/220
classified with: http://purl.uniprot.org/keywords/457
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0008839
classified with: GO_0051287
classified with: GO_0050661
classified with: GO_0016726
classified with: GO_0019877
classified with: GO_0009089
sequence: Q6MRM8-1
proteome: Chromosome

Q6MRM8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0289
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.40.50.720
type: Resource
database: Gene3D
comment: NAD(P)-binding Rossmann-like Domain
signature sequence match: Gene3D 3.40.50.720 match 1

MF_00102
type: Resource
database: HAMAP
comment: DapB
signature sequence match: HAMAP MF 00102 match 1

IPR022663
type: Resource
database: InterPro
comment: DapB_C

IPR000846
type: Resource
database: InterPro
comment: DapB_N

IPR023940
type: Resource
database: InterPro
comment: DHDPR_bac

IPR036291
type: Resource
database: InterPro
comment: NAD(P)-bd_dom_sf

PTHR20836:SF7
type: Resource
database: PANTHER
comment: 4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE
signature sequence match: PANTHER PTHR20836:SF7 match 1

PTHR20836
type: Resource
database: PANTHER
comment: DIHYDRODIPICOLINATE REDUCTASE
signature sequence match: PANTHER PTHR20836 match 1

PF05173
type: Resource
database: Pfam
comment: DapB_C
signature sequence match: Pfam PF05173 match 1

PF01113
type: Resource
database: Pfam
comment: DapB_N
signature sequence match: Pfam PF01113 match 1

PIRSF000161
type: Resource
database: PIRSF
comment: DHPR
signature sequence match: PIRSF PIRSF000161 match 1

SSF55347
type: Resource
database: SUPFAM
comment: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
signature sequence match: SUPFAM SSF55347 match 1

SSF51735
type: Resource
database: SUPFAM
comment: NAD(P)-binding Rossmann-fold domains
signature sequence match: SUPFAM SSF51735 match 1

SIP889671A2F3EEDFCB
type: Structured Name
full name: 4-hydroxy-tetrahydrodipicolinate reductase
short name: HTPA reductase
ec name: 1.17.1.8

dapB
type: Gene
locus name: Bd0047

SIPE021FA3BEC5E0E09
type: Function Annotation
comment: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.

SIP82A71C5D82AC780E
type: Similarity Annotation
comment: Belongs to the DapB family.

SIP710A2E40537634A0
type: Caution Annotation
comment: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

PRO_0000228328
type: Chain Annotation
comment: 4-hydroxy-tetrahydrodipicolinate reductase
mass: 25371
range: 22859178834737198tt1tt229

22859178834737198tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRM8-1

22859178834737198tt229
type: Position
type: ExactPosition
position: 229
reference: Q6MRM8-1

SIPAE2F2B4518AF0B47
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22859178834737198tt133tt133

22859178834737198tt133
type: Position
type: ExactPosition
position: 133
reference: Q6MRM8-1

SIPB94957CD18346935
type: Active Site Annotation
comment: Proton donor
range: 22859178834737198tt137tt137

22859178834737198tt137
type: Position
type: ExactPosition
position: 137
reference: Q6MRM8-1

22859178834737198tt10
type: Position
type: ExactPosition
position: 10
reference: Q6MRM8-1

22859178834737198tt15
type: Position
type: ExactPosition
position: 15
reference: Q6MRM8-1

22859178834737198tt78
type: Position
type: ExactPosition
position: 78
reference: Q6MRM8-1

22859178834737198tt80
type: Position
type: ExactPosition
position: 80
reference: Q6MRM8-1

22859178834737198tt102
type: Position
type: ExactPosition
position: 102
reference: Q6MRM8-1

22859178834737198tt105
type: Position
type: ExactPosition
position: 105
reference: Q6MRM8-1

22859178834737198tt134
type: Position
type: ExactPosition
position: 134
reference: Q6MRM8-1

22859178834737198tt143
type: Position
type: ExactPosition
position: 143
reference: Q6MRM8-1

22859178834737198tt144
type: Position
type: ExactPosition
position: 144
reference: Q6MRM8-1

Q6MRM8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 25371
value: MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEALKDILKKASETKTPVVCGTTGFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFSAISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKLPEALAIRGGGVFGVHKIFAMSDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK

http://purl.uniprot.org/uniprot/Q6MRM8#attribution-DDE0374E5322A356F0027F105F75B112
manual: true
evidence: ECO_0000255
source: MF_00102

http://purl.uniprot.org/uniprot/Q6MRM8#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6MQ94
type: Protein
reviewed: true
created: 2008-06-10
modified: 2023-09-13
version: 113
mnemonic: DDL_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP97EEA9C6D689407F
alternative name: SIP68E9DEFDB2526EAF
alternative name: SIPB2B37D09B53E5142
enzyme: http://purl.uniprot.org/enzyme/6.3.2.4
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPEAAC7F9988053CEB
annotation: SIP4188060887009989
annotation: SIPE4DFFBB2932539F9
annotation: SIP28626C9D885CA80F
annotation: SIP9E2A8E19D872C84F
annotation: SIPFD99F5B8EDCC0124
annotation: PRO_0000341059
annotation: SIP79E8F0748DDAF803
annotation: SIP4424E98A6ED08B4B
annotation: SIPC5AD3E97AA6830D4
annotation: SIP22FCC6AD74E95D84
annotation: SIP029469DFA40E3C4C
annotation: SIP3097CEC9BBD256A0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/961
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/573
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0008716
classified with: GO_0046872
classified with: GO_0071555
classified with: GO_0009252
classified with: GO_0008360
sequence: Q6MQ94-1
proteome: Chromosome

Q6MQ94-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1181
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.30.1490.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, A domain
signature sequence match: Gene3D 3.30.1490.20 match 1

http://purl.uniprot.org/gene3d/3.30.470.20
type: Resource
database: Gene3D
comment: ATP-grasp fold, B domain
signature sequence match: Gene3D 3.30.470.20 match 1

MF_00047
type: Resource
database: HAMAP
comment: Dala_Dala_lig
signature sequence match: HAMAP MF 00047 match 1

IPR011761
type: Resource
database: InterPro
comment: ATP-grasp

IPR013815
type: Resource
database: InterPro
comment: ATP_grasp_subdomain_1

IPR000291
type: Resource
database: InterPro
comment: D-Ala_lig_Van_CS

IPR005905
type: Resource
database: InterPro
comment: D_ala_D_ala

IPR011095
type: Resource
database: InterPro
comment: Dala_Dala_lig_C

IPR011127
type: Resource
database: InterPro
comment: Dala_Dala_lig_N

IPR016185
type: Resource
database: InterPro
comment: PreATP-grasp_dom_sf

TIGR01205
type: Resource
database: NCBIfam
comment: D_ala_D_alaTIGR
signature sequence match: NCBIfam TIGR01205 match 1

PTHR23132
type: Resource
database: PANTHER
comment: D-ALANINE--D-ALANINE LIGASE
signature sequence match: PANTHER PTHR23132 match 1

PTHR23132:SF25
type: Resource
database: PANTHER
comment: D-ALANINE--D-ALANINE LIGASE A
signature sequence match: PANTHER PTHR23132:SF25 match 1

PF07478
type: Resource
database: Pfam
comment: Dala_Dala_lig_C
signature sequence match: Pfam PF07478 match 1

PF01820
type: Resource
database: Pfam
comment: Dala_Dala_lig_N
signature sequence match: Pfam PF01820 match 1

PIRSF039102
type: Resource
database: PIRSF
comment: Ddl/VanB
signature sequence match: PIRSF PIRSF039102 match 1

SSF56059
type: Resource
database: SUPFAM
comment: Glutathione synthetase ATP-binding domain-like
signature sequence match: SUPFAM SSF56059 match 1

SSF52440
type: Resource
database: SUPFAM
comment: PreATP-grasp domain
signature sequence match: SUPFAM SSF52440 match 1

PS50975
type: Resource
database: PROSITE
comment: ATP_GRASP
signature sequence match: PROSITE PS50975 match 1

PS00843
type: Resource
database: PROSITE
comment: DALA_DALA_LIGASE_1
signature sequence match: PROSITE PS00843 match 1

PS00844
type: Resource
database: PROSITE
comment: DALA_DALA_LIGASE_2
signature sequence match: PROSITE PS00844 match 1

SIP97EEA9C6D689407F
type: Structured Name
full name: D-alanine--D-alanine ligase
ec name: 6.3.2.4

SIP68E9DEFDB2526EAF
type: Structured Name
full name: D-Ala-D-Ala ligase

SIPB2B37D09B53E5142
type: Structured Name
full name: D-alanylalanine synthetase

ddl
type: Gene
locus name: Bd0585

SIPEAAC7F9988053CEB
type: Function Annotation
comment: Cell wall formation.

SIPE4DFFBB2932539F9
type: Cofactor Annotation
comment: Binds 2 magnesium or manganese ions per subunit.
cofactor: CHEBI_18420
cofactor: CHEBI_29035

SIPFD99F5B8EDCC0124
type: Similarity Annotation
comment: Belongs to the D-alanine--D-alanine ligase family.

PRO_0000341059
type: Chain Annotation
comment: D-alanine--D-alanine ligase
mass: 40347
range: 22859178816648238tt1tt365

22859178816648238tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MQ94-1

22859178816648238tt365
type: Position
type: ExactPosition
position: 365
reference: Q6MQ94-1

SIP79E8F0748DDAF803
type: Domain Extent Annotation
comment: ATP-grasp
range: 22859178816648238tt145tt347

22859178816648238tt145
type: Position
type: ExactPosition
position: 145
reference: Q6MQ94-1

22859178816648238tt347
type: Position
type: ExactPosition
position: 347
reference: Q6MQ94-1

22859178816648238tt173
type: Position
type: ExactPosition
position: 173
reference: Q6MQ94-1

22859178816648238tt228
type: Position
type: ExactPosition
position: 228
reference: Q6MQ94-1

22859178816648238tt301
type: Position
type: ExactPosition
position: 301
reference: Q6MQ94-1

22859178816648238tt314
type: Position
type: ExactPosition
position: 314
reference: Q6MQ94-1

22859178816648238tt316
type: Position
type: ExactPosition
position: 316
reference: Q6MQ94-1

1
subclass of: CHEBI_18420

2
subclass of: CHEBI_18420

Q6MQ94-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 40347
value: MSMKKIVALIFGGKSAEHEVSLRSAKNVADALDKDKFTPVLIGISKEGSWYRFPDMGVFTEATKIVDSALPSKAEPVALMSLQGKPVLYSLKDHSKTAVDVAFPILHGTMGEDGTIQGLFKMVQLPFVGCGVWSSAAGMDKEIMKRLLAVAKIPNARYLLLTPHQKNDYNEIVKELGSPFFIKPANAGSSVGVHKIKTAEDFVVKLKDAFQFDTKVLAEEFIQGREVECSVMGHNHAPKASLPGEVIPQHEFYSYEAKYIDDNGALLKIPAELSPETTKAVQKMAEQTYQAMGCDGLTRVDFFIRPNGELYINEINTIPGFTKISMYPKMWEASGLSYKDLISQLIQLGFEKFEGEQSLKTSYLD

http://purl.uniprot.org/uniprot/Q6MQ94#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q6MQ94#attribution-A0A5C738C775730E0CCEA3AE6FA50A40
manual: true
evidence: ECO_0000255
source: MF_00047

Q6MGR8
type: Protein
reviewed: true
created: 2006-04-04
modified: 2023-09-13
version: 104
mnemonic: DEOC_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP0E982507E7BF8976
alternative name: SIP373D8463696F2E1E
alternative name: SIPB67C7DC9FEF60F4F
enzyme: http://purl.uniprot.org/enzyme/4.1.2.4
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPCB1968448C55CD46
annotation: SIP125B453EB0157D8B
annotation: SIPA13D1FEBB5A0AB09
annotation: SIP310DB033976E88A0
annotation: SIP2CABDD7A3792A3A5
annotation: PRO_0000231534
annotation: SIPEDBEFC089ADB60B4
annotation: SIPBEEA73C0997D4C34
annotation: SIPCC38C74A4B8E6535
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/704
classified with: GO_0005737
classified with: GO_0004139
classified with: GO_0016052
classified with: GO_0009264
classified with: GO_0046386
sequence: Q6MGR8-1
proteome: Chromosome

Q6MGR8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0274
type: Resource
database: eggNOG
comment: Bacteria

cd00959
type: Resource
database: CDD
comment: DeoC
signature sequence match: CDD cd00959 match 1

MF_00114
type: Resource
database: HAMAP
comment: DeoC_type1
signature sequence match: HAMAP MF 00114 match 1

IPR011343
type: Resource
database: InterPro
comment: DeoC

IPR002915
type: Resource
database: InterPro
comment: DeoC/FbaB/LacD_aldolase

IPR028581
type: Resource
database: InterPro
comment: DeoC_typeI

TIGR00126
type: Resource
database: NCBIfam
comment: deoC
signature sequence match: NCBIfam TIGR00126 match 1

PTHR10889:SF1
type: Resource
database: PANTHER
comment: 2-DEOXY-D-RIBOSE 5-PHOSPHATE ALDOLASE
signature sequence match: PANTHER PTHR10889:SF1 match 1

PTHR10889
type: Resource
database: PANTHER
comment: DEOXYRIBOSE-PHOSPHATE ALDOLASE
signature sequence match: PANTHER PTHR10889 match 1

PF01791
type: Resource
database: Pfam
comment: DeoC
signature sequence match: Pfam PF01791 match 1

PIRSF001357
type: Resource
database: PIRSF
comment: DeoC
signature sequence match: PIRSF PIRSF001357 match 1

SM01133
type: Resource
database: SMART
comment: DeoC
signature sequence match: SMART SM01133 match 1

SIP0E982507E7BF8976
type: Structured Name
full name: Deoxyribose-phosphate aldolase
short name: DERA
ec name: 4.1.2.4

SIP373D8463696F2E1E
type: Structured Name
full name: 2-deoxy-D-ribose 5-phosphate aldolase

SIPB67C7DC9FEF60F4F
type: Structured Name
full name: Phosphodeoxyriboaldolase
short name: Deoxyriboaldolase

deoC
type: Gene
alternative label: dra
locus name: Bd3854

SIPCB1968448C55CD46
type: Function Annotation
comment: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.

SIP2CABDD7A3792A3A5
type: Similarity Annotation
comment: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

PRO_0000231534
type: Chain Annotation
comment: Deoxyribose-phosphate aldolase
mass: 23167
range: 22859178650515502tt1tt220

22859178650515502tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MGR8-1

22859178650515502tt220
type: Position
type: ExactPosition
position: 220
reference: Q6MGR8-1

SIPEDBEFC089ADB60B4
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22859178650515502tt89tt89

22859178650515502tt89
type: Position
type: ExactPosition
position: 89
reference: Q6MGR8-1

SIPBEEA73C0997D4C34
type: Active Site Annotation
comment: Schiff-base intermediate with acetaldehyde
range: 22859178650515502tt151tt151

22859178650515502tt151
type: Position
type: ExactPosition
position: 151
reference: Q6MGR8-1

SIPCC38C74A4B8E6535
type: Active Site Annotation
comment: Proton donor/acceptor
range: 22859178650515502tt180tt180

22859178650515502tt180
type: Position
type: ExactPosition
position: 180
reference: Q6MGR8-1

Q6MGR8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 23167
value: MQLSRYIDHTLLKPEAQTAQIEKLCAEAKEHNFFSVCVNTSYVKTCAELLKDSSVKVCCVVGFPLGAMDTTSKAFETKTAIANGAQEIDMVIQIGALKDRRLDYVRDDIKAVVQAANGHTVKVIIETSLLNQEDKTLACKAALEAGAHFVKTSTGFGGGGATVDDVKLMKSVVGSSMEVKASGGIKDAQQAKSMIDAGATRLGTSSGITIIQGGSVQGGY

http://purl.uniprot.org/uniprot/Q6MGR8#attribution-D051BD8BB754F39F914034C8E7D0A74A
manual: true
evidence: ECO_0000255
source: MF_00114

Q6MRS1
type: Protein
reviewed: true
created: 2005-03-15
modified: 2023-09-13
version: 103
mnemonic: DNAA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPCBCFC2E9BA151A7C
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP9B2A29A596F9939F
annotation: SIPA5F489A430FB5A5C
annotation: SIP896B3720BD62878B
annotation: PRO_0000114137
annotation: SIP1C503B405959BBF8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0003688
classified with: GO_0006270
classified with: GO_0006275
sequence: Q6MRS1-1
proteome: Chromosome

Q6MRS1-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0593
type: Resource
database: eggNOG
comment: Bacteria

cd06571
type: Resource
database: CDD
comment: Bac_DnaA_C
signature sequence match: CDD cd06571 match 1

MF_00377
type: Resource
database: HAMAP
comment: DnaA_bact
signature sequence match: HAMAP MF 00377 match 1

IPR001957
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA

IPR020591
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA-like

IPR018312
type: Resource
database: InterPro
comment: Chromosome_initiator_DnaA_CS

IPR013317
type: Resource
database: InterPro
comment: DnaA

IPR013159
type: Resource
database: InterPro
comment: DnaA_C

IPR038454
type: Resource
database: InterPro
comment: DnaA_N_sf

IPR010921
type: Resource
database: InterPro
comment: Trp_repressor/repl_initiator

TIGR00362
type: Resource
database: NCBIfam
comment: DnaA
signature sequence match: NCBIfam TIGR00362 match 1

PTHR30050
type: Resource
database: PANTHER
comment: CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA
signature sequence match: PANTHER PTHR30050 match 1

PTHR30050:SF2
type: Resource
database: PANTHER
comment: CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA
signature sequence match: PANTHER PTHR30050:SF2 match 1

PF00308
type: Resource
database: Pfam
comment: Bac_DnaA
signature sequence match: Pfam PF00308 match 1

PF08299
type: Resource
database: Pfam
comment: Bac_DnaA_C
signature sequence match: Pfam PF08299 match 1

PR00051
type: Resource
database: PRINTS
comment: DNAA

SM00760
type: Resource
database: SMART
comment: Bac_DnaA_C
signature sequence match: SMART SM00760 match 1

SSF48295
type: Resource
database: SUPFAM
comment: TrpR-like
signature sequence match: SUPFAM SSF48295 match 1

PS01008
type: Resource
database: PROSITE
comment: DNAA
signature sequence match: PROSITE PS01008 match 1

SIPCBCFC2E9BA151A7C
type: Structured Name
full name: Chromosomal replication initiator protein DnaA

dnaA
type: Gene
locus name: Bd0001

SIP9B2A29A596F9939F
type: Function Annotation
comment: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

SIP896B3720BD62878B
type: Similarity Annotation
comment: Belongs to the DnaA family.

PRO_0000114137
type: Chain Annotation
comment: Chromosomal replication initiator protein DnaA
mass: 53998
range: 22859178835128622tt1tt471

22859178835128622tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRS1-1

22859178835128622tt471
type: Position
type: ExactPosition
position: 471
reference: Q6MRS1-1

22859178835128622tt173
type: Position
type: ExactPosition
position: 173
reference: Q6MRS1-1

22859178835128622tt180
type: Position
type: ExactPosition
position: 180
reference: Q6MRS1-1

Q6MRS1-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 53998
value: MELNSSFWTLIKTKMKSRNDNNKLLDTWLDPIEYVSTTGSADRPRLVLGVPNALHQYFVIENLQDKIYTEISDTYGKPFEVEFSITGNKINSHIETSTTPDEVLSGSEILQAQLARAQNIQPTQPRSSSDTLNSELTFSTFVVGKNSEFAHAACYNVARNPGADDYNPLYIYGPVGMGKTHLLHAAGNHIREQYQHLRITYISAERFMNECISAIRRHEMDKFRQKYRENSDILLVDDVQFIARGEAVQEEFFHTVNSFIDSRKQVILASDRMPKDIHGLEDRSRTRLERGLIADITMPDLETRIAILRYKAEKYNVRLPEDVVNYIARISKRSIRELEGNLKKVKMFSELQGLPIDHELVKRILAHHETQSTISVEEIMKLVADHFKVRVLDLKSSTRAKPIVVPRQIAMYLIKKFLDKSLVDIGKSFGGKDHTTVMNALERVKNLQAADQDIAKDIEDLEQRIHNITRV

http://purl.uniprot.org/uniprot/Q6MRS1#attribution-DBF1A02807F1BF3B2D49375A3DDDD731
manual: true
evidence: ECO_0000255
source: MF_00377

Q6MQS6
type: Protein
reviewed: true
created: 2005-07-19
modified: 2023-09-13
version: 101
mnemonic: DNAE2_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP27404080D840AFC3
enzyme: http://purl.uniprot.org/enzyme/2.7.7.7
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP2CFAE21C015D27BF
annotation: SIP01581E069C3B1DC3
annotation: SIP5566B1CB48889CF3
annotation: SIPCEF463847AC32F1B
annotation: PRO_0000103366
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/239
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0008408
classified with: GO_0003887
classified with: GO_0006281
classified with: GO_0006260
classified with: GO_0009432
sequence: Q6MQS6-1
proteome: Chromosome

Q6MQS6-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0587
type: Resource
database: eggNOG
comment: Bacteria

cd04485
type: Resource
database: CDD
comment: DnaE_OBF
signature sequence match: CDD cd04485 match 1

cd07434
type: Resource
database: CDD
comment: PHP_PolIIIA_DnaE2
signature sequence match: CDD cd07434 match 1

http://purl.uniprot.org/gene3d/2.40.50.140
type: Resource
database: Gene3D
comment: Nucleic acid-binding proteins
signature sequence match: Gene3D 2.40.50.140 match 1
signature sequence match: Gene3D 2.40.50.140 match 2

MF_01902
type: Resource
database: HAMAP
comment: DNApol_error_prone
signature sequence match: HAMAP MF 01902 match 1

IPR011708
type: Resource
database: InterPro
comment: DNA_pol3_alpha_NTPase_dom

IPR040982
type: Resource
database: InterPro
comment: DNA_pol3_finger

IPR023073
type: Resource
database: InterPro
comment: DnaE2

IPR004805
type: Resource
database: InterPro
comment: DnaE2/DnaE/PolC

IPR029460
type: Resource
database: InterPro
comment: DNAPol_HHH

IPR012340
type: Resource
database: InterPro
comment: NA-bd_OB-fold

IPR004013
type: Resource
database: InterPro
comment: PHP_dom

IPR003141
type: Resource
database: InterPro
comment: Pol/His_phosphatase_N

IPR016195
type: Resource
database: InterPro
comment: Pol/histidinol_Pase-like

TIGR00594
type: Resource
database: NCBIfam
comment: polc
signature sequence match: NCBIfam TIGR00594 match 1

PTHR32294
type: Resource
database: PANTHER
comment: DNA POLYMERASE III SUBUNIT ALPHA
signature sequence match: PANTHER PTHR32294 match 1

PTHR32294:SF4
type: Resource
database: PANTHER
comment: ERROR-PRONE DNA POLYMERASE
signature sequence match: PANTHER PTHR32294:SF4 match 1

PF07733
type: Resource
database: Pfam
comment: DNA_pol3_alpha
signature sequence match: Pfam PF07733 match 1

PF17657
type: Resource
database: Pfam
comment: DNA_pol3_finger
signature sequence match: Pfam PF17657 match 1

PF14579
type: Resource
database: Pfam
comment: HHH_6
signature sequence match: Pfam PF14579 match 1

PF02811
type: Resource
database: Pfam
comment: PHP
signature sequence match: Pfam PF02811 match 1

SM00481
type: Resource
database: SMART
comment: POLIIIAc
signature sequence match: SMART SM00481 match 1

SSF89550
type: Resource
database: SUPFAM
comment: PHP domain-like
signature sequence match: SUPFAM SSF89550 match 1

SIP27404080D840AFC3
type: Structured Name
full name: Error-prone DNA polymerase
ec name: 2.7.7.7

dnaE2
type: Gene
locus name: Bd0384

SIP2CFAE21C015D27BF
type: Function Annotation
comment: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

SIPCEF463847AC32F1B
type: Similarity Annotation
comment: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

PRO_0000103366
type: Chain Annotation
comment: Error-prone DNA polymerase
mass: 121567
range: 22859178818352686tt1tt1061

22859178818352686tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MQS6-1

22859178818352686tt1061
type: Position
type: ExactPosition
position: 1061
reference: Q6MQS6-1

Q6MQS6-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 121567
value: MTNKALIPSQNSRLPAKPRPRAKGFVELLGRSNFSFLQGASSPEEMVSQAVEFGYDGMALCDLNGLYGVVRGFQTIQSPSLFTASPQVKENFHYLIGSELTLTDESSVVLIPMNKQGYSHLCEILTLGKRQAAKGFSKLSLEQIEKYNQGLLCLALPPWTDERYEKLEKIFDNRLYLPLWRDLTWESQEFCRQGFALEEKYKAQLFVTQRPFMHSPERKPLFDVLTCTLHHTTLAEAKNKLIQNSERCLKSLEDISWLWQDRLDLVEKTVEISARVTFSLNEIRYRYPASSLPSGMTPTEYMRHLTLKGAESRYPEGIPDKALKQIEHELELIKDLQYEDYFLTLKEICDFASERKILYQGRGSAANSVVCFCLGLTAIDPVKMDLLFERFLSRERREPPDIDIDFEHSRREEVIQHIYEKYNERHAAMVCTVIRYRSRMAIRETAKVFGMPLAKINAMIKFMGRDGMKRLLDPAVAADFGMEPGPWKMFMALAQQLHGFPRHLGIHTGGFLITQDPITEMVPVEKATMNGRYVIQWNKDDVDFLRLMKIDVLSLGMLTCLRKCFDLLRDVKGRDYSLATLPADDKPTYDMICRAETVGVFQIESRAQMNTLPRMQPRNFYDLVIEIALIRPGPLQGGMVHPFLKLRQNPPKEIKYAHPALEPILKKTMGIPIFQEQVMKMVVAVADFTPGEADELRRVMSSAWKRKATMGGIEQRLRTGFARHGISSEYADQIFKTIEGFANYGFPESHSASFALLTYASCYLKCHYPDVFACGLLNSQPMGFYAPRTIIAEAQRNGVVVAPLDVQKSDYDYTIEKTAAGDLLRVGLRSIYGIPEVLIRRIEDSRKEEGLYIDLADFIRRTQLPRSVLLKLAAAGAFESFNSNVRELIWNLESLSLDQQSFLWGHPKEQFELGEDDDEPEHLPFESNWDRLRREYDSKGYSVESHPMSVLRTYLHSKSEALREKRFVPYFSSEDLKRMKTKTKVRVAGLVAITQRPPTAKGMCFITLEDEFGFVNIVIHPEIYQKDRTTIYTRSLLEIHGQVEKVGAITNIRAERILPLG

http://purl.uniprot.org/uniprot/Q6MQS6#attribution-A61C2F6BEF3B8993F3A93836BE41F1EC
creator: CollecTF
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/16030231

http://purl.uniprot.org/uniprot/Q6MQS6#attribution-C97B5DABD79E3674D280E6905637DE5B
manual: true
evidence: ECO_0000255
source: MF_01902

Q6MNG0
type: Protein
reviewed: true
created: 2005-04-26
modified: 2023-09-13
version: 111
mnemonic: DNAJ_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPAB5D6734BF88C1A0
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPAA44F109DE7283EF
annotation: SIP34098CD2A0B63903
annotation: SIPAA954C708EF7A788
annotation: SIPEAC970E6FF8DEA57
annotation: SIP0E41C1481E79B423
annotation: SIP1DC4A07361CDF6DD
annotation: PRO_0000070732
annotation: SIP8E02D5729F6C3228
annotation: SIP9CEB5244259413D6
annotation: SIPB817A57E4792B52F
annotation: SIP5120A1CF3EAF31F7
annotation: SIP31F39EA0B90744AB
annotation: SIP84F07747BEF3B4C8
annotation: SIP94748333E53E6847
annotation: SIPFF9BA3C5CDEC9DD3
annotation: SIPA898652955BAA1FF
annotation: SIP160026322DA57E4A
annotation: SIP3AAA6A092F04158D
annotation: SIP6D1C4314D2A976BF
annotation: SIP9EA29A96EA2EA9B4
annotation: SIPEAC7C4A3D588F183
annotation: SIP8E983A4B0D4C3D80
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/346
classified with: http://purl.uniprot.org/keywords/863
classified with: GO_0005737
classified with: GO_0005524
classified with: GO_0031072
classified with: GO_0051082
classified with: GO_0008270
classified with: GO_0006260
classified with: GO_0006457
classified with: GO_0009408
sequence: Q6MNG0-1
proteome: Chromosome

Q6MNG0-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0484
type: Resource
database: eggNOG
comment: Bacteria

cd06257
type: Resource
database: CDD
comment: DnaJ
signature sequence match: CDD cd06257 match 1

cd10747
type: Resource
database: CDD
comment: DnaJ_C
signature sequence match: CDD cd10747 match 1

cd10719
type: Resource
database: CDD
comment: DnaJ_zf
signature sequence match: CDD cd10719 match 1

http://purl.uniprot.org/gene3d/1.10.287.110
type: Resource
database: Gene3D
comment: DnaJ domain
signature sequence match: Gene3D 1.10.287.110 match 1

http://purl.uniprot.org/gene3d/2.10.230.10
type: Resource
database: Gene3D
comment: Heat shock protein DnaJ, cysteine-rich domain
signature sequence match: Gene3D 2.10.230.10 match 1

http://purl.uniprot.org/gene3d/2.60.260.20
type: Resource
database: Gene3D
comment: Urease metallochaperone UreE, N-terminal domain
signature sequence match: Gene3D 2.60.260.20 match 1
signature sequence match: Gene3D 2.60.260.20 match 2

MF_01152
type: Resource
database: HAMAP
comment: DnaJ
signature sequence match: HAMAP MF 01152 match 1

IPR012724
type: Resource
database: InterPro
comment: DnaJ

IPR002939
type: Resource
database: InterPro
comment: DnaJ_C

IPR001623
type: Resource
database: InterPro
comment: DnaJ_domain

IPR018253
type: Resource
database: InterPro
comment: DnaJ_domain_CS

IPR008971
type: Resource
database: InterPro
comment: HSP40/DnaJ_pept-bd

IPR001305
type: Resource
database: InterPro
comment: HSP_DnaJ_Cys-rich_dom

IPR036410
type: Resource
database: InterPro
comment: HSP_DnaJ_Cys-rich_dom_sf

IPR036869
type: Resource
database: InterPro
comment: J_dom_sf

TIGR02349
type: Resource
database: NCBIfam
comment: DnaJ_bact
signature sequence match: NCBIfam TIGR02349 match 1

PTHR43096:SF48
type: Resource
database: PANTHER
comment: CHAPERONE PROTEIN DNAJ
signature sequence match: PANTHER PTHR43096:SF48 match 1

PTHR43096
type: Resource
database: PANTHER
comment: DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED
signature sequence match: PANTHER PTHR43096 match 1

PF00226
type: Resource
database: Pfam
comment: DnaJ
signature sequence match: Pfam PF00226 match 1

PF01556
type: Resource
database: Pfam
comment: DnaJ_C
signature sequence match: Pfam PF01556 match 1

PF00684
type: Resource
database: Pfam
comment: DnaJ_CXXCXGXG
signature sequence match: Pfam PF00684 match 1

PR00625
type: Resource
database: PRINTS
comment: JDOMAIN

SM00271
type: Resource
database: SMART
comment: DnaJ
signature sequence match: SMART SM00271 match 1

SSF46565
type: Resource
database: SUPFAM
comment: Chaperone J-domain
signature sequence match: SUPFAM SSF46565 match 1

SSF57938
type: Resource
database: SUPFAM
comment: DnaJ/Hsp40 cysteine-rich domain
signature sequence match: SUPFAM SSF57938 match 1

SSF49493
type: Resource
database: SUPFAM
comment: HSP40/DnaJ peptide-binding domain
signature sequence match: SUPFAM SSF49493 match 1
signature sequence match: SUPFAM SSF49493 match 2

PS00636
type: Resource
database: PROSITE
comment: DNAJ_1
signature sequence match: PROSITE PS00636 match 1

PS50076
type: Resource
database: PROSITE
comment: DNAJ_2
signature sequence match: PROSITE PS50076 match 1

PS51188
type: Resource
database: PROSITE
comment: ZF_CR
signature sequence match: PROSITE PS51188 match 1

SIPAB5D6734BF88C1A0
type: Structured Name
full name: Chaperone protein DnaJ

dnaJ
type: Gene
locus name: Bd1296

SIPAA44F109DE7283EF
type: Function Annotation
comment: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.

SIP34098CD2A0B63903
type: Cofactor Annotation
comment: Binds 2 Zn(2+) ions per monomer.
cofactor: CHEBI_29105

SIPAA954C708EF7A788
type: Subunit Annotation
comment: Homodimer.

SIP0E41C1481E79B423
type: Domain Annotation
comment: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

SIP1DC4A07361CDF6DD
type: Similarity Annotation
comment: Belongs to the DnaJ family.

PRO_0000070732
type: Chain Annotation
comment: Chaperone protein DnaJ
mass: 40776
range: 22859178767233070tt1tt371

22859178767233070tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MNG0-1

22859178767233070tt371
type: Position
type: ExactPosition
position: 371
reference: Q6MNG0-1

SIP8E02D5729F6C3228
type: Domain Extent Annotation
comment: J
range: 22859178767233070tt6tt71

22859178767233070tt6
type: Position
type: ExactPosition
position: 6
reference: Q6MNG0-1

22859178767233070tt71
type: Position
type: ExactPosition
position: 71
reference: Q6MNG0-1

SIP9CEB5244259413D6
type: Repeat Annotation
comment: CXXCXGXG motif
range: 22859178767233070tt152tt159

22859178767233070tt152
type: Position
type: ExactPosition
position: 152
reference: Q6MNG0-1

22859178767233070tt159
type: Position
type: ExactPosition
position: 159
reference: Q6MNG0-1

SIPB817A57E4792B52F
type: Repeat Annotation
comment: CXXCXGXG motif
range: 22859178767233070tt169tt176

22859178767233070tt169
type: Position
type: ExactPosition
position: 169
reference: Q6MNG0-1

22859178767233070tt176
type: Position
type: ExactPosition
position: 176
reference: Q6MNG0-1

SIP5120A1CF3EAF31F7
type: Repeat Annotation
comment: CXXCXGXG motif
range: 22859178767233070tt191tt198

22859178767233070tt191
type: Position
type: ExactPosition
position: 191
reference: Q6MNG0-1

22859178767233070tt198
type: Position
type: ExactPosition
position: 198
reference: Q6MNG0-1

SIP31F39EA0B90744AB
type: Repeat Annotation
comment: CXXCXGXG motif
range: 22859178767233070tt205tt212

22859178767233070tt205
type: Position
type: ExactPosition
position: 205
reference: Q6MNG0-1

22859178767233070tt212
type: Position
type: ExactPosition
position: 212
reference: Q6MNG0-1

SIP84F07747BEF3B4C8
type: Zinc Finger Annotation
comment: CR-type
range: 22859178767233070tt139tt217

22859178767233070tt139
type: Position
type: ExactPosition
position: 139
reference: Q6MNG0-1

22859178767233070tt217
type: Position
type: ExactPosition
position: 217
reference: Q6MNG0-1

SIP94748333E53E6847
type: Region Annotation
comment: Disordered
range: 22859178767233070tt104tt123

22859178767233070tt104
type: Position
type: ExactPosition
position: 104
reference: Q6MNG0-1

22859178767233070tt123
type: Position
type: ExactPosition
position: 123
reference: Q6MNG0-1

22859178767233070tt155
type: Position
type: ExactPosition
position: 155
reference: Q6MNG0-1

22859178767233070tt172
type: Position
type: ExactPosition
position: 172
reference: Q6MNG0-1

22859178767233070tt194
type: Position
type: ExactPosition
position: 194
reference: Q6MNG0-1

22859178767233070tt208
type: Position
type: ExactPosition
position: 208
reference: Q6MNG0-1

1
subclass of: CHEBI_29105

2
subclass of: CHEBI_29105

Q6MNG0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 40776
value: MAGKRDYYEILGVEKGADQDTIKKAYRKLAMQFHPDKNPGNKEAEEKFKEAAGAYEVLSDAQKRAQYDRFGHDAFTRGGGGGGFTDAEDIFSHFGDIFGDFFGGGMGGQQRQRRNRNEPRRGSDLRYVTEITLKDVITGIEKEIEFDTDKNCDECKGTGAEKGSQVSTCGTCGGSGQVVRQQGFFAMASTCPTCHGQGTVIKNPCKPCKGKGRVAEHRKIRLNIPAGVDTGTRLRVATEGEGGYMGGPPGDLYVEIRVKQHNNFERRNEDLFAELSLPYVQMLLGAEIEVPTVTGKAKLEVPKGTHHGDNVKLVGEGLPSLRGNRRGDIYFTVNVQFPEKLHKDEEKLLREIAKARGLNVTSEGGFFGKKK

http://purl.uniprot.org/uniprot/Q6MNG0#attribution-91DEEFF61680FB8F8CA288D6901560AE
manual: true
evidence: ECO_0000255
source: MF_01152

Q6MNF8
type: Protein
reviewed: true
created: 2006-03-07
modified: 2023-09-13
version: 106
mnemonic: DNAK_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP77347BD26C11F2DD
alternative name: SIPB9F2AC767B62F30E
alternative name: SIP46A93DADC713DCB9
alternative name: SIPE022D25B133FC824
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPC45B64ADB720A82C
annotation: SIPA80A4EEE21D50584
annotation: SIP7218BE85B1DF4588
annotation: PRO_0000225940
annotation: SIPA084D986F4DEF88F
annotation: SIPB921735D4074423F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/346
classified with: GO_0005524
classified with: GO_0140662
classified with: GO_0051082
sequence: Q6MNF8-1
proteome: Chromosome

Q6MNF8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0443
type: Resource
database: eggNOG
comment: Bacteria

cd10234
type: Resource
database: CDD
comment: HSPA9-Ssq1-like_NBD
signature sequence match: CDD cd10234 match 1

MF_00332
type: Resource
database: HAMAP
comment: DnaK
signature sequence match: HAMAP MF 00332 match 1

IPR012725
type: Resource
database: InterPro
comment: Chaperone_DnaK

IPR018181
type: Resource
database: InterPro
comment: Heat_shock_70_CS

IPR029048
type: Resource
database: InterPro
comment: HSP70_C_sf

IPR029047
type: Resource
database: InterPro
comment: HSP70_peptide-bd_sf

IPR013126
type: Resource
database: InterPro
comment: Hsp_70_fam

TIGR02350
type: Resource
database: NCBIfam
comment: prok_dnaK
signature sequence match: NCBIfam TIGR02350 match 1

PTHR19375
type: Resource
database: PANTHER
comment: HEAT SHOCK PROTEIN 70KDA
signature sequence match: PANTHER PTHR19375 match 1

PTHR19375:SF184
type: Resource
database: PANTHER
comment: STRESS-70 PROTEIN, MITOCHONDRIAL
signature sequence match: PANTHER PTHR19375:SF184 match 1

PF00012
type: Resource
database: Pfam
comment: HSP70
signature sequence match: Pfam PF00012 match 1

PR00301
type: Resource
database: PRINTS
comment: HEATSHOCK70

SSF100934
type: Resource
database: SUPFAM
comment: Heat shock protein 70kD (HSP70), C-terminal subdomain
signature sequence match: SUPFAM SSF100934 match 1

SSF100920
type: Resource
database: SUPFAM
comment: Heat shock protein 70kD (HSP70), peptide-binding domain
signature sequence match: SUPFAM SSF100920 match 1

PS00297
type: Resource
database: PROSITE
comment: HSP70_1
signature sequence match: PROSITE PS00297 match 1

PS00329
type: Resource
database: PROSITE
comment: HSP70_2
signature sequence match: PROSITE PS00329 match 1

PS01036
type: Resource
database: PROSITE
comment: HSP70_3
signature sequence match: PROSITE PS01036 match 1

SIP77347BD26C11F2DD
type: Structured Name
full name: Chaperone protein DnaK

SIPB9F2AC767B62F30E
type: Structured Name
full name: HSP70

SIP46A93DADC713DCB9
type: Structured Name
full name: Heat shock 70 kDa protein

SIPE022D25B133FC824
type: Structured Name
full name: Heat shock protein 70

dnaK
type: Gene
locus name: Bd1298

SIPC45B64ADB720A82C
type: Function Annotation
comment: Acts as a chaperone.

SIPA80A4EEE21D50584
type: Induction Annotation
comment: By stress conditions e.g. heat shock.

SIP7218BE85B1DF4588
type: Similarity Annotation
comment: Belongs to the heat shock protein 70 family.

PRO_0000225940
type: Chain Annotation
comment: Chaperone protein DnaK
mass: 68382
range: 22859178767169582tt1tt637

22859178767169582tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MNF8-1

22859178767169582tt637
type: Position
type: ExactPosition
position: 637
reference: Q6MNF8-1

SIPA084D986F4DEF88F
type: Region Annotation
comment: Disordered
range: 22859178767169582tt596tt637

22859178767169582tt596
type: Position
type: ExactPosition
position: 596
reference: Q6MNF8-1

SIPB921735D4074423F
type: Modified Residue Annotation
comment: Phosphothreonine; by autocatalysis
range: 22859178767169582tt195tt195

22859178767169582tt195
type: Position
type: ExactPosition
position: 195
reference: Q6MNF8-1

Q6MNF8-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 68382
value: MGKIIGIDLGTTNSCVAIMEGGEPKVLVNEEGARTTPSVVAYTKDGDRLVGQIAKRQAVTNPENTIYSAKRFIGRRFEEIQEEIKLVPYTVVAKGNDCAFKVQGKTASPEEIGAAVLAKLKKVAEDYLGEPVTEAVVTVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGMDKKKDEKIVIYDFGGGTFDVSILEVGDGVVEVRATNGDTHLGGDNFDTVILEWLITEFKKDQAIDLKNDKMALQRLKEAAEKAKIELSSAQETEINLPFITADQSGPKHLQTRLSRAKFDQMTEDLVKRSMEPCRKALADSGLKASEIDEVVLVGGSTRIPAIQKAVKDFFGKEPNRSVNPDEVVAIGAAVQGGVLAGDVKDVLLLDVTPLSLGIETLGGVMTTLIERNTAIPSKKSQVFSTAADNQPAVDIHVLQGERKMAGDNKTLGRFELVGIPPAPRGVPQVEVTFDIDANGILHVSAKDMSSGKSQQIKITAQSGMSEDEIKRAVADAEGHAEEDKRKAEAATQRNNLDNLVYQTEKLIKDSGAQLPESEVKSANEAVAEAKKILENKSASGDELKGAFERLQNLTHKLTSELYKKQGAQPGAEGQQADAAEGGEASANKGGDDVIDADYKDVN

http://purl.uniprot.org/uniprot/Q6MNF8#attribution-DF48ACB5BC6928786EC8A207943949A8
manual: true
evidence: ECO_0000255
source: MF_00332

Q6MRL9
type: Protein
reviewed: true
created: 2008-01-15
modified: 2023-09-13
version: 112
mnemonic: DNLJ_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP61544389502FCBE3
alternative name: SIPBF6E3D52175D0838
enzyme: http://purl.uniprot.org/enzyme/6.5.1.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP67320A7A387BBA57
annotation: SIP40F26C342203C8E0
annotation: SIP647B23C5284BB7A5
annotation: SIP4ECD7ADF1E23C8F9
annotation: PRO_0000313138
annotation: SIP9589AEBDE628472C
annotation: SIP6863C16B4F4CFF4A
annotation: SIPF3D6A62795A4B422
annotation: SIP302A191E4328BD22
annotation: SIP9846985630E8C480
annotation: SIP1729309350DEA8DA
annotation: SIP8D9D81F830D167F7
annotation: SIPB1BD87E9427EE35C
annotation: SIP53D8205E00DF8E72
annotation: SIP82D3D35FEF300B1E
annotation: SIP5026283E7856DC43
annotation: SIP49C8789C887FA995
annotation: SIP4B43FA3722E8B5E1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0003677
classified with: GO_0003911
classified with: GO_0046872
classified with: GO_0006281
classified with: GO_0006260
sequence: Q6MRL9-1
proteome: Chromosome

Q6MRL9-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0272
type: Resource
database: eggNOG
comment: Bacteria

cd17748
type: Resource
database: CDD
comment: BRCT_DNA_ligase_like
signature sequence match: CDD cd17748 match 1

cd00114
type: Resource
database: CDD
comment: LIGANc
signature sequence match: CDD cd00114 match 1

http://purl.uniprot.org/gene3d/1.10.150.20
type: Resource
database: Gene3D
comment: 5' to 3' exonuclease, C-terminal subdomain
signature sequence match: Gene3D 1.10.150.20 match 1
signature sequence match: Gene3D 1.10.150.20 match 2

http://purl.uniprot.org/gene3d/3.40.50.10190
type: Resource
database: Gene3D
comment: BRCT domain
signature sequence match: Gene3D 3.40.50.10190 match 1

http://purl.uniprot.org/gene3d/3.30.470.30
type: Resource
database: Gene3D
comment: DNA ligase/mRNA capping enzyme
signature sequence match: Gene3D 3.30.470.30 match 1

http://purl.uniprot.org/gene3d/1.10.287.610
type: Resource
database: Gene3D
comment: Helix hairpin bin
signature sequence match: Gene3D 1.10.287.610 match 1

MF_01588
type: Resource
database: HAMAP
comment: DNA_ligase_A
signature sequence match: HAMAP MF 01588 match 1

IPR001357
type: Resource
database: InterPro
comment: BRCT_dom

IPR036420
type: Resource
database: InterPro
comment: BRCT_dom_sf

IPR041663
type: Resource
database: InterPro
comment: DisA/LigA_HHH

IPR001679
type: Resource
database: InterPro
comment: DNA_ligase

IPR018239
type: Resource
database: InterPro
comment: DNA_ligase_AS

IPR033136
type: Resource
database: InterPro
comment: DNA_ligase_CS

IPR013839
type: Resource
database: InterPro
comment: DNAligase_adenylation

IPR013840
type: Resource
database: InterPro
comment: DNAligase_N

IPR003583
type: Resource
database: InterPro
comment: Hlx-hairpin-Hlx_DNA-bd_motif

IPR004150
type: Resource
database: InterPro
comment: NAD_DNA_ligase_OB

IPR010994
type: Resource
database: InterPro
comment: RuvA_2-like

IPR004149
type: Resource
database: InterPro
comment: Znf_DNAligase_C4

TIGR00575
type: Resource
database: NCBIfam
comment: dnlj
signature sequence match: NCBIfam TIGR00575 match 1

PTHR23389
type: Resource
database: PANTHER
comment: CHROMOSOME TRANSMISSION FIDELITY FACTOR 18
signature sequence match: PANTHER PTHR23389 match 1

PTHR23389:SF9
type: Resource
database: PANTHER
comment: DNA LIGASE
signature sequence match: PANTHER PTHR23389:SF9 match 1

PF00533
type: Resource
database: Pfam
comment: BRCT
signature sequence match: Pfam PF00533 match 1

PF01653
type: Resource
database: Pfam
comment: DNA_ligase_aden
signature sequence match: Pfam PF01653 match 1

PF03120
type: Resource
database: Pfam
comment: DNA_ligase_OB
signature sequence match: Pfam PF03120 match 1

PF03119
type: Resource
database: Pfam
comment: DNA_ligase_ZBD
signature sequence match: Pfam PF03119 match 1

PF12826
type: Resource
database: Pfam
comment: HHH_2
signature sequence match: Pfam PF12826 match 1

PF14520
type: Resource
database: Pfam
comment: HHH_5
signature sequence match: Pfam PF14520 match 1

PIRSF001604
type: Resource
database: PIRSF
comment: LigA
signature sequence match: PIRSF PIRSF001604 match 1

SM00292
type: Resource
database: SMART
comment: BRCT
signature sequence match: SMART SM00292 match 1

SM00278
type: Resource
database: SMART
comment: HhH1
signature sequence match: SMART SM00278 match 1
signature sequence match: SMART SM00278 match 2
signature sequence match: SMART SM00278 match 3

SM00532
type: Resource
database: SMART
comment: LIGANc
signature sequence match: SMART SM00532 match 1

SSF52113
type: Resource
database: SUPFAM
comment: BRCT domain
signature sequence match: SUPFAM SSF52113 match 1

SSF56091
type: Resource
database: SUPFAM
comment: DNA ligase/mRNA capping enzyme, catalytic domain
signature sequence match: SUPFAM SSF56091 match 1

SSF50249
type: Resource
database: SUPFAM
comment: Nucleic acid-binding proteins
signature sequence match: SUPFAM SSF50249 match 1
signature sequence match: SUPFAM SSF50249 match 2

SSF47781
type: Resource
database: SUPFAM
comment: RuvA domain 2-like
signature sequence match: SUPFAM SSF47781 match 1

PS50172
type: Resource
database: PROSITE
comment: BRCT
signature sequence match: PROSITE PS50172 match 1

PS01055
type: Resource
database: PROSITE
comment: DNA_LIGASE_N1
signature sequence match: PROSITE PS01055 match 1

PS01056
type: Resource
database: PROSITE
comment: DNA_LIGASE_N2
signature sequence match: PROSITE PS01056 match 1

SIP61544389502FCBE3
type: Structured Name
full name: DNA ligase
ec name: 6.5.1.2

SIPBF6E3D52175D0838
type: Structured Name
full name: Polydeoxyribonucleotide synthase [NAD(+)]

ligA
type: Gene
locus name: Bd0057

SIP67320A7A387BBA57
type: Function Annotation
comment: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

SIP4ECD7ADF1E23C8F9
type: Similarity Annotation
comment: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.

PRO_0000313138
type: Chain Annotation
comment: DNA ligase
mass: 76371
range: 22859178834671918tt1tt684

22859178834671918tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRL9-1

22859178834671918tt684
type: Position
type: ExactPosition
position: 684
reference: Q6MRL9-1

SIP9589AEBDE628472C
type: Domain Extent Annotation
comment: BRCT
range: 22859178834671918tt609tt684

22859178834671918tt609
type: Position
type: ExactPosition
position: 609
reference: Q6MRL9-1

SIP6863C16B4F4CFF4A
type: Active Site Annotation
comment: N6-AMP-lysine intermediate
range: 22859178834671918tt131tt131

22859178834671918tt131
type: Position
type: ExactPosition
position: 131
reference: Q6MRL9-1

22859178834671918tt48
type: Position
type: ExactPosition
position: 48
reference: Q6MRL9-1

22859178834671918tt52
type: Position
type: ExactPosition
position: 52
reference: Q6MRL9-1

22859178834671918tt97
type: Position
type: ExactPosition
position: 97
reference: Q6MRL9-1

22859178834671918tt98
type: Position
type: ExactPosition
position: 98
reference: Q6MRL9-1

22859178834671918tt129
type: Position
type: ExactPosition
position: 129
reference: Q6MRL9-1

22859178834671918tt152
type: Position
type: ExactPosition
position: 152
reference: Q6MRL9-1

22859178834671918tt189
type: Position
type: ExactPosition
position: 189
reference: Q6MRL9-1

22859178834671918tt310
type: Position
type: ExactPosition
position: 310
reference: Q6MRL9-1

22859178834671918tt334
type: Position
type: ExactPosition
position: 334
reference: Q6MRL9-1

22859178834671918tt429
type: Position
type: ExactPosition
position: 429
reference: Q6MRL9-1

22859178834671918tt432
type: Position
type: ExactPosition
position: 432
reference: Q6MRL9-1

22859178834671918tt447
type: Position
type: ExactPosition
position: 447
reference: Q6MRL9-1

22859178834671918tt452
type: Position
type: ExactPosition
position: 452
reference: Q6MRL9-1

Q6MRL9-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 76371
value: MPDAFCRDWTSEMGANYSMSKKRHEELKKIISEHDHNYHVLDKPTITDYEYDQLFAELLDIEKNPKGLDLSDSPSQRVGGTVLEGFTKAQHRLPMLSLANSYSPEDIFEFDERVRKFLNTEDPVEYLCELKFDGLSMELIYENGQLVRAITRGDGTVGEDVTHNIKTIKSIPLKLSHKNPPPLLEVRGEVLMFKEDFARLNETQQENGQQTFANPRNAAAGTVRQLDSRIAASRPLRFFGYALGAVEGETFNTQKNIQEYFNDHGIPTVLPYKEDLLVVAKGPEEVVKYYHHIEKVRPKLPFDIDGVVIKVNSLRLQEDLGLVARSPRWATAAKFKPEQAQTTVEDIVVQVGRTGALTPVAIMKPVKVGGVTVTNATLHNQDEITRKDIRIGDTVIIQRAGDVIPEVVEVVNPDKRPADRLPYSIPERCPACDSVAVKAEGEVVTRCVNPLCIAVVKESLKHFVARRAMNIDKVGDRLIETLVDNKLLTRFSDFYRLTKEQILSLERQGDKSADNIIKSIENSKNPTLARFIFALGIRFVGEQTGKHLADHFLTIDKFLEASEEELLQVPEIGAKVAKSIRDWTGNPKLVDEVKAMIELGVKIAGPVRAQEGSLSGMSFLITGTLPVKRDDAKDLIERNGGKILGSVSSKLNYLVVGDDPGSKVEKAQGLGVKIISWEELQAMI

http://purl.uniprot.org/uniprot/Q6MRL9#attribution-205EE578AABEFC2A9D16E41084DB3D31
manual: true
evidence: ECO_0000255
source: MF_01588

Q6MMK8
type: Protein
reviewed: true
created: 2005-02-15
modified: 2023-09-13
version: 99
mnemonic: DTD_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP34666DAC82CE7EC4
alternative name: SIPBCD097FF3A2902C8
enzyme: http://purl.uniprot.org/enzyme/3.1.1.96
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPCD75B07D9D29DAFE
annotation: SIPAF4B22BCC24EB823
annotation: SIP14E7CD89E2FA2E2D
annotation: SIP9760A65C32C8D5A7
annotation: SIPFE284D3E11D587B7
annotation: SIPBAC81B060E80AEEA
annotation: SIP6FD8D7E58B411F0A
annotation: PRO_0000164524
annotation: SIP20F20D852F85935F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/820
classified with: GO_0005737
classified with: GO_0051499
classified with: GO_0106026
classified with: GO_0043908
classified with: GO_0000049
classified with: GO_0019478
sequence: MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV
proteome: Chromosome

Q6MMK8-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1490
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.50.80.10
type: Resource
database: Gene3D
comment: D-tyrosyl-tRNA(Tyr) deacylase
signature sequence match: Gene3D 3.50.80.10 match 1

MF_00518
type: Resource
database: HAMAP
comment: Deacylase_Dtd
signature sequence match: HAMAP MF 00518 match 1

IPR003732
type: Resource
database: InterPro
comment: Daa-tRNA_deacyls_DTD

IPR023509
type: Resource
database: InterPro
comment: DTD-like_sf

TIGR00256
type: Resource
database: NCBIfam
comment: D-aminoacyl-tRNA deacylase
signature sequence match: NCBIfam TIGR00256 match 1

PTHR10472:SF5
type: Resource
database: PANTHER
comment: D-AMINOACYL-TRNA DEACYLASE 1
signature sequence match: PANTHER PTHR10472:SF5 match 1

PTHR10472
type: Resource
database: PANTHER
comment: D-TYROSYL-TRNA TYR DEACYLASE
signature sequence match: PANTHER PTHR10472 match 1

PF02580
type: Resource
database: Pfam
comment: Tyr_Deacylase
signature sequence match: Pfam PF02580 match 1

SSF69500
type: Resource
database: SUPFAM
comment: DTD-like
signature sequence match: SUPFAM SSF69500 match 1

SIP34666DAC82CE7EC4
type: Structured Name
full name: D-aminoacyl-tRNA deacylase
short name: DTD
ec name: 3.1.1.96

SIPBCD097FF3A2902C8
type: Structured Name
full name: Gly-tRNA(Ala) deacylase

dtd
type: Gene
locus name: Bd1619

SIPCD75B07D9D29DAFE
type: Function Annotation
comment: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.

SIP9760A65C32C8D5A7
type: Subunit Annotation
comment: Homodimer.

SIPBAC81B060E80AEEA
type: Domain Annotation
comment: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.

SIP6FD8D7E58B411F0A
type: Similarity Annotation
comment: Belongs to the DTD family.

PRO_0000164524
type: Chain Annotation
comment: D-aminoacyl-tRNA deacylase
mass: 15540
range: 22859178750720046tt1tt145

22859178750720046tt1
type: Position
type: ExactPosition
position: 1
reference: MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV

22859178750720046tt145
type: Position
type: ExactPosition
position: 145
reference: MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV

SIP20F20D852F85935F
type: Motif Annotation
comment: Gly-cisPro motif, important for rejection of L-amino acids
range: 22859178750720046tt137tt138

22859178750720046tt137
type: Position
type: ExactPosition
position: 137
reference: MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV

22859178750720046tt138
type: Position
type: ExactPosition
position: 138
reference: MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV

MKAVVQRVQNASVVVDGKLVSSIDKGYLTLLGVAKGDSEEQLQKLMTKILALRIFPDETGKMNLSLKDVGGQHLIVSQFTLLGDASKGNRPSFIGAELPDRAKELYEKALVLSESQGVKTQGGIFGADMKVSLLNDGPVTLLLEV
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 15540

http://purl.uniprot.org/uniprot/Q6MMK8#attribution-2FCA4DC1F7A9F9BB916B3F5139223798
manual: true
evidence: ECO_0000255
source: MF_00518

P61906
type: Protein
reviewed: true
created: 2004-06-07
modified: 2023-09-13
version: 100
mnemonic: DUT_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP0EF699CB001DE938
alternative name: SIP83C3B220815E2900
enzyme: http://purl.uniprot.org/enzyme/3.6.1.23
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPE967ADF164EC0640
annotation: SIP39017C2AE53C08DB
annotation: SIPBABEE20DF4DF8EEC
annotation: SIP79D3EA3F25B4D0F8
annotation: SIPF1E05AA09B6E12D8
annotation: PRO_0000182829
annotation: SIP18A632D6290EF2F7
annotation: SIP727449238613879D
annotation: SIP0AB5538581706D29
annotation: SIP3DDD0C56B95FE640
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/546
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004170
classified with: GO_0000287
classified with: GO_0006226
classified with: GO_0046081
sequence: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA
proteome: Chromosome

P61906-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0756
type: Resource
database: eggNOG
comment: Bacteria

cd07557
type: Resource
database: CDD
comment: trimeric_dUTPase
signature sequence match: CDD cd07557 match 1

MF_00116
type: Resource
database: HAMAP
comment: dUTPase_bact
signature sequence match: HAMAP MF 00116 match 1

IPR008181
type: Resource
database: InterPro
comment: dUTPase

IPR029054
type: Resource
database: InterPro
comment: dUTPase-like

IPR036157
type: Resource
database: InterPro
comment: dUTPase-like_sf

IPR033704
type: Resource
database: InterPro
comment: dUTPase_trimeric

TIGR00576
type: Resource
database: NCBIfam
comment: dut
signature sequence match: NCBIfam TIGR00576 match 1

PTHR11241
type: Resource
database: PANTHER
comment: DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
signature sequence match: PANTHER PTHR11241 match 1

PTHR11241:SF0
type: Resource
database: PANTHER
comment: DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
signature sequence match: PANTHER PTHR11241:SF0 match 1

PF00692
type: Resource
database: Pfam
comment: dUTPase
signature sequence match: Pfam PF00692 match 1

SSF51283
type: Resource
database: SUPFAM
comment: dUTPase-like
signature sequence match: SUPFAM SSF51283 match 1

SIP0EF699CB001DE938
type: Structured Name
full name: Deoxyuridine 5'-triphosphate nucleotidohydrolase
short name: dUTPase
ec name: 3.6.1.23

SIP83C3B220815E2900
type: Structured Name
full name: dUTP pyrophosphatase

dut
type: Gene
locus name: Bd1553

SIPE967ADF164EC0640
type: Function Annotation
comment: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

SIPF1E05AA09B6E12D8
type: Similarity Annotation
comment: Belongs to the dUTPase family.

PRO_0000182829
type: Chain Annotation
comment: Deoxyuridine 5'-triphosphate nucleotidohydrolase
mass: 15934
range: 22577583177610798tt1tt149

22577583177610798tt1
type: Position
type: ExactPosition
position: 1
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt149
type: Position
type: ExactPosition
position: 149
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt68
type: Position
type: ExactPosition
position: 68
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt70
type: Position
type: ExactPosition
position: 70
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt81
type: Position
type: ExactPosition
position: 81
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt85
type: Position
type: ExactPosition
position: 85
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt87
type: Position
type: ExactPosition
position: 87
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

22577583177610798tt95
type: Position
type: ExactPosition
position: 95
reference: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA

substrate

MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA
type: Simple Sequence
modified: 2004-06-07
version: 1
mass: 15934

http://purl.uniprot.org/uniprot/P61906#attribution-5B839E442FD54E13E6D88F3F856D315E
manual: true
evidence: ECO_0000255
source: MF_00116

Q6MJ13
type: Protein
reviewed: true
created: 2005-03-29
modified: 2023-09-13
version: 111
mnemonic: EFG1_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPA275428E7C3F8D56
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP6EDE154D6A11AF51
annotation: SIP329E311089597FA8
annotation: SIP4044FD942429D7EF
annotation: PRO_0000091075
annotation: SIPD154C902E545A869
annotation: SIP8FAE34E0C89C69FF
annotation: SIP21107E1A8DFFF65A
annotation: SIP43A143549932A618
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0097216
classified with: GO_0003746
sequence: Q6MJ13-1
proteome: Chromosome

Q6MJ13-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0480
type: Resource
database: eggNOG
comment: Bacteria

cd01886
type: Resource
database: CDD
comment: EF-G
signature sequence match: CDD cd01886 match 1

cd16262
type: Resource
database: CDD
comment: EFG_III
signature sequence match: CDD cd16262 match 1

cd03713
type: Resource
database: CDD
comment: EFG_mtEFG_C
signature sequence match: CDD cd03713 match 1

cd04088
type: Resource
database: CDD
comment: EFG_mtEFG_II
signature sequence match: CDD cd04088 match 1

http://purl.uniprot.org/gene3d/3.30.70.870
type: Resource
database: Gene3D
comment: Elongation Factor G (Translational Gtpase), domain 3
signature sequence match: Gene3D 3.30.70.870 match 1

http://purl.uniprot.org/gene3d/2.40.30.10
type: Resource
database: Gene3D
comment: Translation factors
signature sequence match: Gene3D 2.40.30.10 match 1
signature sequence match: Gene3D 2.40.30.10 match 2

MF 00054 B
type: Resource
database: HAMAP
comment: EF_G_EF_2_B
signature sequence match: HAMAP MF 00054 B match 1

IPR041095
type: Resource
database: InterPro
comment: EFG_II

IPR009022
type: Resource
database: InterPro
comment: EFG_III

IPR035647
type: Resource
database: InterPro
comment: EFG_III/V

IPR035649
type: Resource
database: InterPro
comment: EFG_V

IPR000640
type: Resource
database: InterPro
comment: EFG_V-like

IPR004161
type: Resource
database: InterPro
comment: EFTu-like_2

IPR031157
type: Resource
database: InterPro
comment: G_TR_CS

IPR020568
type: Resource
database: InterPro
comment: Ribosomal_S5_D2-typ_fold

IPR014721
type: Resource
database: InterPro
comment: Ribosomal_S5_D2-typ_fold_subgr

IPR005225
type: Resource
database: InterPro
comment: Small_GTP-bd_dom

IPR000795
type: Resource
database: InterPro
comment: T_Tr_GTP-bd_dom

IPR009000
type: Resource
database: InterPro
comment: Transl_B-barrel_sf

IPR004540
type: Resource
database: InterPro
comment: Transl_elong_EFG/EF2

IPR005517
type: Resource
database: InterPro
comment: Transl_elong_EFG/EF2_IV

TIGR00484
type: Resource
database: NCBIfam
comment: EF-G
signature sequence match: NCBIfam TIGR00484 match 1

TIGR00231
type: Resource
database: NCBIfam
comment: small_GTP
signature sequence match: NCBIfam TIGR00231 match 1

PTHR43261:SF1
type: Resource
database: PANTHER
comment: RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43261:SF1 match 1

PTHR43261
type: Resource
database: PANTHER
comment: TRANSLATION ELONGATION FACTOR G-RELATED
signature sequence match: PANTHER PTHR43261 match 1

PF00679
type: Resource
database: Pfam
comment: EFG_C
signature sequence match: Pfam PF00679 match 1

PF14492
type: Resource
database: Pfam
comment: EFG_III
signature sequence match: Pfam PF14492 match 1

PF03764
type: Resource
database: Pfam
comment: EFG_IV
signature sequence match: Pfam PF03764 match 1

PF00009
type: Resource
database: Pfam
comment: GTP_EFTU
signature sequence match: Pfam PF00009 match 1

PF03144
type: Resource
database: Pfam
comment: GTP_EFTU_D2
signature sequence match: Pfam PF03144 match 1

PR00315
type: Resource
database: PRINTS
comment: ELONGATNFCT

SM00838
type: Resource
database: SMART
comment: EFG_C
signature sequence match: SMART SM00838 match 1

SM00889
type: Resource
database: SMART
comment: EFG_IV
signature sequence match: SMART SM00889 match 1

SSF54980
type: Resource
database: SUPFAM
comment: EF-G C-terminal domain-like
signature sequence match: SUPFAM SSF54980 match 1
signature sequence match: SUPFAM SSF54980 match 2

SSF54211
type: Resource
database: SUPFAM
comment: Ribosomal protein S5 domain 2-like
signature sequence match: SUPFAM SSF54211 match 1
signature sequence match: SUPFAM SSF54211 match 2

SSF50447
type: Resource
database: SUPFAM
comment: Translation proteins
signature sequence match: SUPFAM SSF50447 match 1
signature sequence match: SUPFAM SSF50447 match 2

PS00301
type: Resource
database: PROSITE
comment: G_TR_1
signature sequence match: PROSITE PS00301 match 1

PS51722
type: Resource
database: PROSITE
comment: G_TR_2
signature sequence match: PROSITE PS51722 match 1

SIPA275428E7C3F8D56
type: Structured Name
full name: Elongation factor G 1
short name: EF-G 1

fusA1
type: Gene
locus name: Bd2979

SIP6EDE154D6A11AF51
type: Function Annotation
comment: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

SIP4044FD942429D7EF
type: Similarity Annotation
comment: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

PRO_0000091075
type: Chain Annotation
comment: Elongation factor G 1
mass: 77090
range: 22859178698683182tt1tt701

22859178698683182tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MJ13-1

22859178698683182tt701
type: Position
type: ExactPosition
position: 701
reference: Q6MJ13-1

SIPD154C902E545A869
type: Domain Extent Annotation
comment: tr-type G
range: 22859178698683182tt13tt288

22859178698683182tt13
type: Position
type: ExactPosition
position: 13
reference: Q6MJ13-1

22859178698683182tt288
type: Position
type: ExactPosition
position: 288
reference: Q6MJ13-1

22859178698683182tt22
type: Position
type: ExactPosition
position: 22
reference: Q6MJ13-1

22859178698683182tt29
type: Position
type: ExactPosition
position: 29
reference: Q6MJ13-1

22859178698683182tt86
type: Position
type: ExactPosition
position: 86
reference: Q6MJ13-1

22859178698683182tt90
type: Position
type: ExactPosition
position: 90
reference: Q6MJ13-1

22859178698683182tt140
type: Position
type: ExactPosition
position: 140
reference: Q6MJ13-1

22859178698683182tt143
type: Position
type: ExactPosition
position: 143
reference: Q6MJ13-1

Q6MJ13-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 77090
value: MSAKDPKVVADLKYTRNIGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGDATMDWMVQEQERGITITSAATMAFWKDHRINIIDTPGHVDFTIEVERSLRVLDGAIAVFDGVNGVEPQSETVWKQADKYKVPRICFVNKMDRVGADFVMSFGTIKEKLNANPIPVQVPIGMEDTFRGVVDLLENKAYMWDQSGMGDHFEITDVPNDMKEEVNRFRTEVIEKIVEFEDELLEKYLNGEEVTVPELKRALRKGTLELKAFPVFCGAAFKNKGVQPLLDGVIDYLPSPLEVPAIVGHDPERPDKEIICKTEFDAHAAALAFKIANDPFAGTLTYIRVYSGEVKVGEQLLNPRTQKKERIQKLVKMHANSREEINSLKAGDIGAVIGLKFTGTGDTLCESSHAVVLETITFPEPVISVAVEAKSSADQEKMLAGLAKLEKEDPSCRLRTDPETGQILLSGMGELHLEILVDRLLREHKIQANVGKPQVSYRETITVAAKAEHVYEREIAGETHFAKVSLSIEPISQADGIQFISKVAVSKEFTAPMLKAAESGFREAAEVGPLASCSMLGIKGTLNSVEVRPDSSSEMAFKAAASLAFRDAVKAASVELLEPIFKLEVTCPDDFVGNIVGDLNARRGKILAMNVKQGGGQVISAEAPLASLFGYATDVRSLSQGRASFSMEFLEYAIVPAKVKTDILHKMGRY

http://purl.uniprot.org/uniprot/Q6MJ13#attribution-32C07E6EED4C7B5B70DAD629E6ACEA88
manual: true
evidence: ECO_0000255
source: MF_00054

Q6MP77
type: Protein
reviewed: true
created: 2005-03-29
modified: 2023-09-13
version: 110
mnemonic: EFG2_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP407E58A2A7D08DEC
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP04A6EA289E816E5B
annotation: SIPDB9A8C1D312F2B6C
annotation: SIP96BB9511523D36A1
annotation: PRO_0000091076
annotation: SIP40DFE852CE1EA423
annotation: SIPFE6A75D33CB35295
annotation: SIP1935DE5279CFB6FE
annotation: SIP6E062ADDDBC90E95
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0097216
classified with: GO_0003746
sequence: Q6MP77-1
proteome: Chromosome

Q6MP77-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

cd01434
type: Resource
database: CDD
comment: EFG_mtEFG1_IV
signature sequence match: CDD cd01434 match 1

cd04097
type: Resource
database: CDD
comment: mtEFG1_C
signature sequence match: CDD cd04097 match 1

cd04091
type: Resource
database: CDD
comment: mtEFG1_II_like
signature sequence match: CDD cd04091 match 1

PTHR43636
type: Resource
database: PANTHER
comment: ELONGATION FACTOR G, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43636 match 1

PTHR43636:SF2
type: Resource
database: PANTHER
comment: ELONGATION FACTOR G, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43636:SF2 match 1

SIP407E58A2A7D08DEC
type: Structured Name
full name: Elongation factor G 2
short name: EF-G 2

fusA2
type: Gene
alternative label: fusA-2
locus name: Bd0987

SIP04A6EA289E816E5B
type: Function Annotation
comment: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

SIP96BB9511523D36A1
type: Similarity Annotation
comment: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

PRO_0000091076
type: Chain Annotation
comment: Elongation factor G 2
mass: 78146
range: 22859178799740718tt1tt702

22859178799740718tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MP77-1

22859178799740718tt702
type: Position
type: ExactPosition
position: 702
reference: Q6MP77-1

SIP40DFE852CE1EA423
type: Domain Extent Annotation
comment: tr-type G
range: 22859178799740718tt8tt285

22859178799740718tt8
type: Position
type: ExactPosition
position: 8
reference: Q6MP77-1

22859178799740718tt285
type: Position
type: ExactPosition
position: 285
reference: Q6MP77-1

22859178799740718tt17
type: Position
type: ExactPosition
position: 17
reference: Q6MP77-1

22859178799740718tt24
type: Position
type: ExactPosition
position: 24
reference: Q6MP77-1

22859178799740718tt84
type: Position
type: ExactPosition
position: 84
reference: Q6MP77-1

22859178799740718tt88
type: Position
type: ExactPosition
position: 88
reference: Q6MP77-1

22859178799740718tt138
type: Position
type: ExactPosition
position: 138
reference: Q6MP77-1

22859178799740718tt141
type: Position
type: ExactPosition
position: 141
reference: Q6MP77-1

Q6MP77-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 78146
value: MSKKWNIDMVRNIGISAHIDSGKTTTSERILFYGGRIHAIHEVRGKDGVGATMDSMDLEREKGITIQSAATQVQWKDYTINLIDTPGHVDFTVEVERSLRVLDGAILLLCGVAGVQSQSITVDRQMKRYNVPRLAFVNKLDRQGANPYRVTDALIEKLRLNAVMIQIPIGLEDQHRGHVDLTDMKAYINQGESGENVLVEEIPADLVETAKKYRQIMIGKLADVDSAIEEKFLMEEEPTTEEIRAAIRKGTIGLKLVPVLCGSAFKNKGVQRLMDAVTYYLPSPAEKKEQALDITKNEEKFDLHPDPTKPLVALAFKLQETPFGQLTYMRVYQGKMGKGDFIVNQVNKKSVKIPRLVRMHSDKMEDIDVSYAGDIVALFGIDCASGDTFCDENIQASMQSMHVPDSVISLAIAPKDKTAANNFSKALQKFRKEDPTFRVHRDEESNETIISGMGELHLEIYVERMKREFNCEVIVGQPQVAYRETISVEAPYDYTHKKQTGGSGQYAKIVGKIQPLPPQEDGAVFKFENKVVGGRIPKEFIPAVEEGFKEQTVKGPLIGFPIVGVEVVLEDGAYHDVDSSYMAFKIAGMAALREVYASAKPTVLEPIMKLETTVPDEYQGSAVGQINQRRGSIVATTAFEGNCVIEAEVPLTEMFGYSTDLRSATKGKGEFSMEFAKYAPVPRNIQEELAKKYQAKRAAEQK

http://purl.uniprot.org/uniprot/Q6MP77#attribution-32C07E6EED4C7B5B70DAD629E6ACEA88
manual: true
evidence: ECO_0000255
source: MF_00054

Q6MKB4
type: Protein
reviewed: true
created: 2004-08-16
modified: 2023-09-13
version: 102
mnemonic: EFP_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP42E8051B8F3706F6
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP732312BD0A7B8EED
annotation: SIP1AB8782C57F9F08C
annotation: SIP19D82138E91F3EAF
annotation: SIP4E5EB9B52395CFC1
annotation: PRO_0000094203
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003746
sequence: MYETSDFRKGLKIMLEGKPYVIVDFQHVKPGKGNQFTRTKLRNMLTGQNLESTFKSGEKFEVPNVENKEMSFLYKDDTGYNFMSQETFEQIAMSEEDLGEAKYYLTENLKVVILFYNEKAVACDVPKAVNLTVAQTDPGIKGDRVTGATKPATMETGLTVGVPLHINEGDVLRIDTSTGEYVERVSQK
proteome: Chromosome

Q6MKB4-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0231
type: Resource
database: eggNOG
comment: Bacteria

cd04470
type: Resource
database: CDD
comment: S1_EF-P_repeat_1
signature sequence match: CDD cd04470 match 1

cd05794
type: Resource
database: CDD
comment: S1_EF-P_repeat_2
signature sequence match: CDD cd05794 match 1

MF_00141
type: Resource
database: HAMAP
comment: EF_P
signature sequence match: HAMAP MF 00141 match 1

IPR015365
type: Resource
database: InterPro
comment: Elong-fact-P_C

IPR014722
type: Resource
database: InterPro
comment: Rib_L2_dom2

IPR020599
type: Resource
database: InterPro
comment: Transl_elong_fac_P/YeiP

IPR013185
type: Resource
database: InterPro
comment: Transl_elong_KOW-like

IPR001059
type: Resource
database: InterPro
comment: Transl_elong_P/YeiP_cen

IPR013852
type: Resource
database: InterPro
comment: Transl_elong_P/YeiP_CS

IPR011768
type: Resource
database: InterPro
comment: Transl_elongation_fac_P

IPR008991
type: Resource
database: InterPro
comment: Translation_prot_SH3-like_sf

TIGR00038
type: Resource
database: NCBIfam
comment: efp
signature sequence match: NCBIfam TIGR00038 match 1

PTHR30053
type: Resource
database: PANTHER
comment: ELONGATION FACTOR P
signature sequence match: PANTHER PTHR30053 match 1

PTHR30053:SF12
type: Resource
database: PANTHER
comment: ELONGATION FACTOR P (EF-P) FAMILY PROTEIN
signature sequence match: PANTHER PTHR30053:SF12 match 1

PF01132
type: Resource
database: Pfam
comment: EFP
signature sequence match: Pfam PF01132 match 1

PF08207
type: Resource
database: Pfam
comment: EFP_N
signature sequence match: Pfam PF08207 match 1

PF09285
type: Resource
database: Pfam
comment: Elong-fact-P_C
signature sequence match: Pfam PF09285 match 1

PIRSF005901
type: Resource
database: PIRSF
comment: EF-P
signature sequence match: PIRSF PIRSF005901 match 1

SM01185
type: Resource
database: SMART
comment: EFP
signature sequence match: SMART SM01185 match 1

SM00841
type: Resource
database: SMART
comment: Elong-fact-P_C
signature sequence match: SMART SM00841 match 1

SSF50104
type: Resource
database: SUPFAM
comment: Translation proteins SH3-like domain
signature sequence match: SUPFAM SSF50104 match 1

PS01275
type: Resource
database: PROSITE
comment: EFP
signature sequence match: PROSITE PS01275 match 1

SIP42E8051B8F3706F6
type: Structured Name
full name: Elongation factor P
short name: EF-P

efp
type: Gene
locus name: Bd2491

SIP732312BD0A7B8EED
type: Function Annotation
comment: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

SIP4E5EB9B52395CFC1
type: Similarity Annotation
comment: Belongs to the elongation factor P family.

PRO_0000094203
type: Chain Annotation
comment: Elongation factor P
mass: 21154
range: 22859178716574766tt1tt188

22859178716574766tt1
type: Position
type: ExactPosition
position: 1
reference: MYETSDFRKGLKIMLEGKPYVIVDFQHVKPGKGNQFTRTKLRNMLTGQNLESTFKSGEKFEVPNVENKEMSFLYKDDTGYNFMSQETFEQIAMSEEDLGEAKYYLTENLKVVILFYNEKAVACDVPKAVNLTVAQTDPGIKGDRVTGATKPATMETGLTVGVPLHINEGDVLRIDTSTGEYVERVSQK

22859178716574766tt188
type: Position
type: ExactPosition
position: 188
reference: MYETSDFRKGLKIMLEGKPYVIVDFQHVKPGKGNQFTRTKLRNMLTGQNLESTFKSGEKFEVPNVENKEMSFLYKDDTGYNFMSQETFEQIAMSEEDLGEAKYYLTENLKVVILFYNEKAVACDVPKAVNLTVAQTDPGIKGDRVTGATKPATMETGLTVGVPLHINEGDVLRIDTSTGEYVERVSQK

MYETSDFRKGLKIMLEGKPYVIVDFQHVKPGKGNQFTRTKLRNMLTGQNLESTFKSGEKFEVPNVENKEMSFLYKDDTGYNFMSQETFEQIAMSEEDLGEAKYYLTENLKVVILFYNEKAVACDVPKAVNLTVAQTDPGIKGDRVTGATKPATMETGLTVGVPLHINEGDVLRIDTSTGEYVERVSQK
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 21154

http://purl.uniprot.org/uniprot/Q6MKB4#attribution-68AEDF1632F0BC61D700CEF2CC98DAC2
manual: true
evidence: ECO_0000255
source: MF_00141

P61331
type: Protein
reviewed: true
created: 2004-05-10
modified: 2023-09-13
version: 100
mnemonic: EFTS_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPFF0ED0AA27B8537C
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP8D97D0C35821E296
annotation: SIPE7AD2EB9A5FC1E49
annotation: SIPCE436E94142DAD64
annotation: PRO_0000161082
annotation: SIP08123A1ED14A0B6D
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0003746
sequence: P61331-1
proteome: Chromosome

P61331-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0264
type: Resource
database: eggNOG
comment: Bacteria

cd14275
type: Resource
database: CDD
comment: UBA_EF-Ts
signature sequence match: CDD cd14275 match 1

http://purl.uniprot.org/gene3d/1.10.8.10
type: Resource
database: Gene3D
comment: DNA helicase RuvA subunit, C-terminal domain
signature sequence match: Gene3D 1.10.8.10 match 1

http://purl.uniprot.org/gene3d/3.30.479.20
type: Resource
database: Gene3D
comment: Elongation factor Ts, dimerisation domain
signature sequence match: Gene3D 3.30.479.20 match 1
signature sequence match: Gene3D 3.30.479.20 match 2

MF_00050
type: Resource
database: HAMAP
comment: EF_Ts
signature sequence match: HAMAP MF 00050 match 1

IPR036402
type: Resource
database: InterPro
comment: EF-Ts_dimer_sf

IPR001816
type: Resource
database: InterPro
comment: Transl_elong_EFTs/EF1B

IPR014039
type: Resource
database: InterPro
comment: Transl_elong_EFTs/EF1B_dimer

IPR018101
type: Resource
database: InterPro
comment: Transl_elong_Ts_CS

IPR009060
type: Resource
database: InterPro
comment: UBA-like_sf

TIGR00116
type: Resource
database: NCBIfam
comment: tsf
signature sequence match: NCBIfam TIGR00116 match 1

PTHR11741
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TS
signature sequence match: PANTHER PTHR11741 match 1

PTHR11741:SF0
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TS, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11741:SF0 match 1

PF00889
type: Resource
database: Pfam
comment: EF_TS
signature sequence match: Pfam PF00889 match 1

SSF54713
type: Resource
database: SUPFAM
comment: Elongation factor Ts (EF-Ts), dimerisation domain
signature sequence match: SUPFAM SSF54713 match 1
signature sequence match: SUPFAM SSF54713 match 2

SSF46934
type: Resource
database: SUPFAM
comment: UBA-like
signature sequence match: SUPFAM SSF46934 match 1

PS01126
type: Resource
database: PROSITE
comment: EF_TS_1
signature sequence match: PROSITE PS01126 match 1

PS01127
type: Resource
database: PROSITE
comment: EF_TS_2
signature sequence match: PROSITE PS01127 match 1

SIPFF0ED0AA27B8537C
type: Structured Name
full name: Elongation factor Ts
short name: EF-Ts

tsf
type: Gene
locus name: Bd3782

SIP8D97D0C35821E296
type: Function Annotation
comment: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.

SIPCE436E94142DAD64
type: Similarity Annotation
comment: Belongs to the EF-Ts family.

PRO_0000161082
type: Chain Annotation
comment: Elongation factor Ts
mass: 32957
range: 22577583077142830tt1tt308

22577583077142830tt1
type: Position
type: ExactPosition
position: 1
reference: P61331-1

22577583077142830tt308
type: Position
type: ExactPosition
position: 308
reference: P61331-1

SIP08123A1ED14A0B6D
type: Region Annotation
comment: Involved in Mg(2+) ion dislocation from EF-Tu
range: 22577583077142830tt79tt82

22577583077142830tt79
type: Position
type: ExactPosition
position: 79
reference: P61331-1

22577583077142830tt82
type: Position
type: ExactPosition
position: 82
reference: P61331-1

P61331-1
type: Simple Sequence
modified: 2004-05-10
version: 1
mass: 32957
value: MSISATLVKELREKTNAGMMDCKKALEATSGDFNAAVEWLRVKGLGAAAKKADRIAAEGAVFAELHGNTGVVIEINSETDFVARNDGFKALAANVVSHLAKTNLEGDVLAQAYAADSSKKLGDLFTEATATIGEKIVLRRQEKYTATATSLVHTYLHGEGKIGVMIEVGASKPEAVSNPALKTFAQDVALHIAAMNPMAISSEQIPADVVSKEKEILTAKNLESGKKPEMIEKIVEGQIRKFLAENCLLDQPFVKNPDMKVSDLAKSVGKEIGADVTVKRFVRFELGAGIEKKTNDFAAEVAAQMKGH

http://purl.uniprot.org/uniprot/P61331#attribution-7640461A89C5EECC81FABE53E97D5FB6
manual: true
evidence: ECO_0000255
source: MF_00050

Q6MJ00
type: Protein
reviewed: true
created: 2008-01-15
modified: 2023-09-13
version: 115
mnemonic: EFTU_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPFBC236343C54F98E
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPD4729D279CA1E18D
annotation: SIP73CF961F095D0F42
annotation: SIP07AC9EEB3F80596E
annotation: SIP96478AF4552A41E9
annotation: PRO_1000015614
annotation: SIPB5576CFA3741F96F
annotation: SIPE2E2012BCF01AFC1
annotation: SIP3BEF957C9881230D
annotation: SIP41A9F68942A27767
annotation: SIP9C91932C3E1B39F8
annotation: SIPCC542CE525FF9907
annotation: SIP40FEAB46A86F2FE0
annotation: SIPCE7E66911991E4DE
annotation: SIP03428A312B2E537E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/251
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005525
classified with: GO_0003924
classified with: GO_0097216
classified with: GO_0003746
sequence: Q6MJ00-1
proteome: Chromosome

Q6MJ00-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0050
type: Resource
database: eggNOG
comment: Bacteria

cd01884
type: Resource
database: CDD
comment: EF_Tu
signature sequence match: CDD cd01884 match 1

cd03697
type: Resource
database: CDD
comment: EFTU_II
signature sequence match: CDD cd03697 match 1

cd03707
type: Resource
database: CDD
comment: EFTU_III
signature sequence match: CDD cd03707 match 1

MF 00118 B
type: Resource
database: HAMAP
comment: EF_Tu_B
signature sequence match: HAMAP MF 00118 B match 1

IPR041709
type: Resource
database: InterPro
comment: EF-Tu_GTP-bd

IPR033720
type: Resource
database: InterPro
comment: EFTU_2

IPR009001
type: Resource
database: InterPro
comment: Transl_elong_EF1A/Init_IF2_C

IPR004541
type: Resource
database: InterPro
comment: Transl_elong_EFTu/EF1A_bac/org

IPR004160
type: Resource
database: InterPro
comment: Transl_elong_EFTu/EF1A_C

TIGR00485
type: Resource
database: NCBIfam
comment: EF-Tu
signature sequence match: NCBIfam TIGR00485 match 1

PTHR43721:SF22
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TU, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43721:SF22 match 1

PTHR43721
type: Resource
database: PANTHER
comment: ELONGATION FACTOR TU-RELATED
signature sequence match: PANTHER PTHR43721 match 1

PF03143
type: Resource
database: Pfam
comment: GTP_EFTU_D3
signature sequence match: Pfam PF03143 match 1

SSF50465
type: Resource
database: SUPFAM
comment: EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
signature sequence match: SUPFAM SSF50465 match 1

SIPFBC236343C54F98E
type: Structured Name
full name: Elongation factor Tu
short name: EF-Tu

tuf
type: Gene
locus name: Bd2994

SIPD4729D279CA1E18D
type: Function Annotation
comment: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

SIP73CF961F095D0F42
type: Subunit Annotation
comment: Monomer.

SIP96478AF4552A41E9
type: Similarity Annotation
comment: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

PRO_1000015614
type: Chain Annotation
comment: Elongation factor Tu
mass: 43266
range: 22859178698616878tt1tt396

22859178698616878tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MJ00-1

22859178698616878tt396
type: Position
type: ExactPosition
position: 396
reference: Q6MJ00-1

SIPB5576CFA3741F96F
type: Domain Extent Annotation
comment: tr-type G
range: 22859178698616878tt10tt206

22859178698616878tt10
type: Position
type: ExactPosition
position: 10
reference: Q6MJ00-1

22859178698616878tt206
type: Position
type: ExactPosition
position: 206
reference: Q6MJ00-1

SIPE2E2012BCF01AFC1
type: Region Annotation
comment: G1
range: 22859178698616878tt19tt26

22859178698616878tt19
type: Position
type: ExactPosition
position: 19
reference: Q6MJ00-1

22859178698616878tt26
type: Position
type: ExactPosition
position: 26
reference: Q6MJ00-1

SIP3BEF957C9881230D
type: Region Annotation
comment: G2
range: 22859178698616878tt60tt64

22859178698616878tt60
type: Position
type: ExactPosition
position: 60
reference: Q6MJ00-1

22859178698616878tt64
type: Position
type: ExactPosition
position: 64
reference: Q6MJ00-1

SIP41A9F68942A27767
type: Region Annotation
comment: G3
range: 22859178698616878tt81tt84

22859178698616878tt81
type: Position
type: ExactPosition
position: 81
reference: Q6MJ00-1

22859178698616878tt84
type: Position
type: ExactPosition
position: 84
reference: Q6MJ00-1

SIP9C91932C3E1B39F8
type: Region Annotation
comment: G4
range: 22859178698616878tt136tt139

22859178698616878tt136
type: Position
type: ExactPosition
position: 136
reference: Q6MJ00-1

22859178698616878tt139
type: Position
type: ExactPosition
position: 139
reference: Q6MJ00-1

SIPCC542CE525FF9907
type: Region Annotation
comment: G5
range: 22859178698616878tt174tt176

22859178698616878tt174
type: Position
type: ExactPosition
position: 174
reference: Q6MJ00-1

22859178698616878tt176
type: Position
type: ExactPosition
position: 176
reference: Q6MJ00-1

22859178698616878tt85
type: Position
type: ExactPosition
position: 85
reference: Q6MJ00-1

Q6MJ00-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 43266
value: MSKEKFTRNKPHVNIGTIGHVDHGKTTLTAAITTTLAASGKAQAMAYDQIDKSPEEKARGITISTTHVEYETDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSSADGPMPQTREHILLARQVGVPALVVFMNKVDMVDDKELLELVELEVRELLSKYEFPGDDIPVVKGSALKALEGDTSEIGRPAIMKLMEACDTYIPAPVRAVDKTFLMPVEDVFSISGRGTVVTGRVERGIVKVGDEIEIVGIRPTQKTTVTGIEMFRKLLDEGQAGDNCGVLLRGTKKEDVERGQVLVKPGTVKPHKKFKAEAYILTKEEGGRHTPFFNGYRPQFYFRTTDVTGVCTLKAGTEMVMPGDKIEVSVELIAPIAMEKELRFAIREGGRTVGAGVVTEILE

http://purl.uniprot.org/uniprot/Q6MJ00#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q6MJ00#attribution-9F28E18146AAED8DA8E9A76B5244B856
manual: true
evidence: ECO_0000255
source: MF_00118

Q6MPP2
type: Protein
reviewed: true
created: 2006-12-12
modified: 2023-09-13
version: 109
mnemonic: ENGB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPB44EC63E49740C42
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPAEB4006DA1757B7A
annotation: SIP01FB7D95AC8BB23C
annotation: SIP3CEDA541E775DE83
annotation: PRO_0000266824
annotation: SIP261624B9CB8D8D6B
annotation: SIP6AB55243C6909FC8
annotation: SIP56C4D910A6A18572
annotation: SIP671A9DE48B77CB05
annotation: SIP57AA05E3BBD61489
annotation: SIP7BA3A524A153FC93
annotation: SIP68E6A71BF85992DD
annotation: SIP3238510C92EBEB1F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/717
classified with: GO_0005525
classified with: GO_0046872
classified with: GO_0000917
sequence: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE
proteome: Chromosome

Q6MPP2-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0218
type: Resource
database: eggNOG
comment: Bacteria

cd01876
type: Resource
database: CDD
comment: YihA_EngB
signature sequence match: CDD cd01876 match 1

MF_00321
type: Resource
database: HAMAP
comment: GTPase_EngB
signature sequence match: HAMAP MF 00321 match 1

IPR030393
type: Resource
database: InterPro
comment: G_ENGB_dom

IPR006073
type: Resource
database: InterPro
comment: GTP-bd

IPR019987
type: Resource
database: InterPro
comment: GTP-bd_ribosome_bio_YsxC

TIGR03598
type: Resource
database: NCBIfam
comment: GTPase_YsxC
signature sequence match: NCBIfam TIGR03598 match 1

PTHR11649:SF13
type: Resource
database: PANTHER
comment: ENGB-TYPE G DOMAIN-CONTAINING PROTEIN
signature sequence match: PANTHER PTHR11649:SF13 match 1

PTHR11649
type: Resource
database: PANTHER
comment: MSS1/TRME-RELATED GTP-BINDING PROTEIN
signature sequence match: PANTHER PTHR11649 match 1

PF01926
type: Resource
database: Pfam
comment: MMR_HSR1
signature sequence match: Pfam PF01926 match 1

PR00326
type: Resource
database: PRINTS
comment: GTP1OBG

PS51706
type: Resource
database: PROSITE
comment: G_ENGB
signature sequence match: PROSITE PS51706 match 1

SIPB44EC63E49740C42
type: Structured Name
full name: Probable GTP-binding protein EngB

engB
type: Gene
locus name: Bd0806

SIPAEB4006DA1757B7A
type: Function Annotation
comment: Necessary for normal cell division and for the maintenance of normal septation.

SIP3CEDA541E775DE83
type: Similarity Annotation
comment: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

PRO_0000266824
type: Chain Annotation
comment: Probable GTP-binding protein EngB
mass: 22528
range: 22859178801377838tt1tt200

22859178801377838tt1
type: Position
type: ExactPosition
position: 1
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt200
type: Position
type: ExactPosition
position: 200
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

SIP261624B9CB8D8D6B
type: Domain Extent Annotation
comment: EngB-type G
range: 22859178801377838tt30tt199

22859178801377838tt30
type: Position
type: ExactPosition
position: 30
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt199
type: Position
type: ExactPosition
position: 199
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt38
type: Position
type: ExactPosition
position: 38
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt45
type: Position
type: ExactPosition
position: 45
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt64
type: Position
type: ExactPosition
position: 64
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt68
type: Position
type: ExactPosition
position: 68
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt66
type: Position
type: ExactPosition
position: 66
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt82
type: Position
type: ExactPosition
position: 82
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt85
type: Position
type: ExactPosition
position: 85
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt149
type: Position
type: ExactPosition
position: 149
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt152
type: Position
type: ExactPosition
position: 152
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt178
type: Position
type: ExactPosition
position: 178
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

22859178801377838tt180
type: Position
type: ExactPosition
position: 180
reference: MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE

MGGALIVLAMPKTIQFIKSAVLEKDFPVHKKAEVAIAGRSNAGKSSFINALTKNKIAKVSSTPGKTRLLNFFELDQSYVMVDMPGYGFAARSGDEMREWHRMIETYLMNREQLRGLLLVMDIRRSWTEDEELLKEFSERRGFPLAVVLTKADKMSRSQMLQAVAKVKKASGLSAVFGVSALKKEGQDAVEDYIYENWIKE
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 22528

http://purl.uniprot.org/uniprot/Q6MPP2#attribution-77B02FDEAED58C51211277159852D254
manual: true
evidence: ECO_0000255
source: MF_00321

Q6MPQ2
type: Protein
reviewed: true
created: 2005-02-15
modified: 2023-09-13
version: 120
mnemonic: ENO_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP5AA414AACCA1AAAA
alternative name: SIP85097F1903432050
alternative name: SIP92F03028F9AEFC78
enzyme: http://purl.uniprot.org/enzyme/4.2.1.11
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP3F35770FD235ADB5
annotation: SIP27AC6F882D81830F
annotation: SIP9B89270757144321
annotation: SIPA872EDDA56F0A77B
annotation: SIPC77E7616431D72A8
annotation: SIPAA5761DE59D0886C
annotation: SIPB930DB0A83909F2D
annotation: PRO_0000133845
annotation: SIP87C41C9E31CC9291
annotation: SIP7996E64C2954E28F
annotation: SIP30B41905DB3348F4
annotation: SIPAE57D38AF6BDB229
annotation: SIPB0193333DDF23B26
annotation: SIPD2DC14A0626CE421
annotation: SIPCB5194A55D55B4CE
annotation: SIPF43CBC88274837C3
annotation: SIP3017A036D5132691
annotation: SIP52CAA55882B9A2A5
annotation: SIP4F002F47E7EFC71A
annotation: SIP88B9358F197B84A3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/324
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/964
classified with: GO_0009986
classified with: GO_0005576
classified with: GO_0000015
classified with: GO_0000287
classified with: GO_0004634
classified with: GO_0006096
sequence: Q6MPQ2-1
proteome: Chromosome

Q6MPQ2-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0148
type: Resource
database: eggNOG
comment: Bacteria

cd03313
type: Resource
database: CDD
comment: enolase
signature sequence match: CDD cd03313 match 1

http://purl.uniprot.org/gene3d/3.20.20.120
type: Resource
database: Gene3D
comment: Enolase-like C-terminal domain
signature sequence match: Gene3D 3.20.20.120 match 1

http://purl.uniprot.org/gene3d/3.30.390.10
type: Resource
database: Gene3D
comment: Enolase-like, N-terminal domain
signature sequence match: Gene3D 3.30.390.10 match 1

MF_00318
type: Resource
database: HAMAP
comment: Enolase
signature sequence match: HAMAP MF 00318 match 1

IPR000941
type: Resource
database: InterPro
comment: Enolase

IPR036849
type: Resource
database: InterPro
comment: Enolase-like_C_sf

IPR029017
type: Resource
database: InterPro
comment: Enolase-like_N

IPR020810
type: Resource
database: InterPro
comment: Enolase_C

IPR020809
type: Resource
database: InterPro
comment: Enolase_CS

IPR020811
type: Resource
database: InterPro
comment: Enolase_N

TIGR01060
type: Resource
database: NCBIfam
comment: eno
signature sequence match: NCBIfam TIGR01060 match 1

PTHR11902
type: Resource
database: PANTHER
comment: ENOLASE
signature sequence match: PANTHER PTHR11902 match 1

PTHR11902:SF1
type: Resource
database: PANTHER
comment: ENOLASE
signature sequence match: PANTHER PTHR11902:SF1 match 1

PF00113
type: Resource
database: Pfam
comment: Enolase_C
signature sequence match: Pfam PF00113 match 1

PF03952
type: Resource
database: Pfam
comment: Enolase_N
signature sequence match: Pfam PF03952 match 1

PIRSF001400
type: Resource
database: PIRSF
comment: Enolase
signature sequence match: PIRSF PIRSF001400 match 1

PR00148
type: Resource
database: PRINTS
comment: ENOLASE

SFLDF00002
type: Resource
database: SFLD
comment: enolase
signature sequence match: SFLD SFLDF00002 match 1

SFLDG00178
type: Resource
database: SFLD
comment: enolase
signature sequence match: SFLD SFLDG00178 match 1

SM01192
type: Resource
database: SMART
comment: Enolase_C
signature sequence match: SMART SM01192 match 1

SM01193
type: Resource
database: SMART
comment: Enolase_N
signature sequence match: SMART SM01193 match 1

SSF51604
type: Resource
database: SUPFAM
comment: Enolase C-terminal domain-like
signature sequence match: SUPFAM SSF51604 match 1

SSF54826
type: Resource
database: SUPFAM
comment: Enolase N-terminal domain-like
signature sequence match: SUPFAM SSF54826 match 1

PS00164
type: Resource
database: PROSITE
comment: ENOLASE
signature sequence match: PROSITE PS00164 match 1

SIP5AA414AACCA1AAAA
type: Structured Name
full name: Enolase
ec name: 4.2.1.11

SIP85097F1903432050
type: Structured Name
full name: 2-phospho-D-glycerate hydro-lyase

SIP92F03028F9AEFC78
type: Structured Name
full name: 2-phosphoglycerate dehydratase

eno
type: Gene
locus name: Bd0796

SIP3F35770FD235ADB5
type: Function Annotation
comment: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.

SIPA872EDDA56F0A77B
type: Activity Regulation Annotation
comment: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

SIPAA5761DE59D0886C
type: Subcellular Location Annotation
comment: Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
located in: SIPB85BE2AD81C4325A
located in: SIP1C6F16A657241C15
located in: SIPF960BCF54EEA17DF

SIPB930DB0A83909F2D
type: Similarity Annotation
comment: Belongs to the enolase family.

PRO_0000133845
type: Chain Annotation
comment: Enolase
mass: 45773
range: 22859178801443374tt1tt422

22859178801443374tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MPQ2-1

22859178801443374tt422
type: Position
type: ExactPosition
position: 422
reference: Q6MPQ2-1

SIP87C41C9E31CC9291
type: Active Site Annotation
comment: Proton donor
range: 22859178801443374tt205tt205

22859178801443374tt205
type: Position
type: ExactPosition
position: 205
reference: Q6MPQ2-1

SIP7996E64C2954E28F
type: Active Site Annotation
comment: Proton acceptor
range: 22859178801443374tt335tt335

22859178801443374tt335
type: Position
type: ExactPosition
position: 335
reference: Q6MPQ2-1

22859178801443374tt155
type: Position
type: ExactPosition
position: 155
reference: Q6MPQ2-1

22859178801443374tt164
type: Position
type: ExactPosition
position: 164
reference: Q6MPQ2-1

22859178801443374tt242
type: Position
type: ExactPosition
position: 242
reference: Q6MPQ2-1

22859178801443374tt283
type: Position
type: ExactPosition
position: 283
reference: Q6MPQ2-1

22859178801443374tt310
type: Position
type: ExactPosition
position: 310
reference: Q6MPQ2-1

SIP52CAA55882B9A2A5
type: Binding Site Annotation
comment: covalent; in inhibited form
ligand: SIP6155B73171216805
range: 22859178801443374tt335tt335

22859178801443374tt362
type: Position
type: ExactPosition
position: 362
reference: Q6MPQ2-1

22859178801443374tt365
type: Position
type: ExactPosition
position: 365
reference: Q6MPQ2-1

22859178801443374tt386
type: Position
type: ExactPosition
position: 386
reference: Q6MPQ2-1

substrate

Q6MPQ2-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 45773
value: MSEIISVISREILDSRGNPTVEVEVTTADGNMGRAAVPSGASTGAHEACELRDGDKNRFLGKGVYKAVDNVREKIAPEIVGLQATEQVYIDKILRDIDGTENKSNLGANAILGVSLAVAKAAAKDCRLPLYRYVGGSQASRLPVPLMNVLNGGAHANNGLDIQEFMIVPTVNNSYAESLRAGTEIFHTLKKILAKKGLSTAVGDEGGFAPKLGSNQEALDLLMNAIVDAGYDPGQNVFLALDVAATEMFKEGKYEWQGGHISPTELLGIYKSWAEKYPLVSIEDGFAEDDWDSWVQSTAQMGSTMQLIGDDLFVTNPKRLRMGLEKKAGNALLVKVNQIGTLTETYEAVNLAQRNKFRTIMSHRSGETEDVTIADLAVGLNCHQIKTGSLCRGERTAKYNQLLRIEEDLGGMGLYWDKAAFR

http://purl.uniprot.org/uniprot/Q6MPQ2#attribution-425FAA66CD8F359F13E44030E74CCC1B
manual: true
evidence: ECO_0000255
source: MF_00318

Q6MR96
type: Protein
reviewed: true
created: 2005-06-07
modified: 2023-09-13
version: 99
mnemonic: EX7S_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP93EEC285E984A394
alternative name: SIP9BB5A74DB0F55505
enzyme: http://purl.uniprot.org/enzyme/3.1.11.6
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP2B3F05FF1317D67A
annotation: SIP567AC3D7E01FCE5E
annotation: SIPC28C67F3561581BC
annotation: SIPCA016F971963D50E
annotation: SIP5BD5473C8916BA89
annotation: PRO_0000206924
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/269
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0009318
classified with: GO_0008855
classified with: GO_0006308
sequence: MDFEKKLGRLEEIVQKMEKGDLALEESLKLFEEGVKLSRECHQRLNEAESKVKLLMSVGADGQPVTTDFTSEEN
proteome: Chromosome

Q6MR96-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1722
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.287.1040
type: Resource
database: Gene3D
comment: Exonuclease VII, small subunit
signature sequence match: Gene3D 1.10.287.1040 match 1

MF_00337
type: Resource
database: HAMAP
comment: Exonuc_7_S
signature sequence match: HAMAP MF 00337 match 1

IPR003761
type: Resource
database: InterPro
comment: Exonuc_VII_S

IPR037004
type: Resource
database: InterPro
comment: Exonuc_VII_ssu_sf

TIGR01280
type: Resource
database: NCBIfam
comment: xseB
signature sequence match: NCBIfam TIGR01280 match 1

PTHR34137
type: Resource
database: PANTHER
comment: EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT
signature sequence match: PANTHER PTHR34137 match 1

PTHR34137:SF1
type: Resource
database: PANTHER
comment: EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT
signature sequence match: PANTHER PTHR34137:SF1 match 1

PF02609
type: Resource
database: Pfam
comment: Exonuc_VII_S
signature sequence match: Pfam PF02609 match 1

SSF116842
type: Resource
database: SUPFAM
comment: XseB-like
signature sequence match: SUPFAM SSF116842 match 1

SIP93EEC285E984A394
type: Structured Name
full name: Exodeoxyribonuclease 7 small subunit
ec name: 3.1.11.6

SIP9BB5A74DB0F55505
type: Structured Name
full name: Exodeoxyribonuclease VII small subunit
short name: Exonuclease VII small subunit

xseB
type: Gene
locus name: Bd0198

SIP2B3F05FF1317D67A
type: Function Annotation
comment: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.

SIPC28C67F3561581BC
type: Subunit Annotation
comment: Heterooligomer composed of large and small subunits.

SIP5BD5473C8916BA89
type: Similarity Annotation
comment: Belongs to the XseB family.

PRO_0000206924
type: Chain Annotation
comment: Exodeoxyribonuclease 7 small subunit
mass: 8414
range: 22859178833425966tt1tt74

22859178833425966tt1
type: Position
type: ExactPosition
position: 1
reference: MDFEKKLGRLEEIVQKMEKGDLALEESLKLFEEGVKLSRECHQRLNEAESKVKLLMSVGADGQPVTTDFTSEEN

22859178833425966tt74
type: Position
type: ExactPosition
position: 74
reference: MDFEKKLGRLEEIVQKMEKGDLALEESLKLFEEGVKLSRECHQRLNEAESKVKLLMSVGADGQPVTTDFTSEEN

MDFEKKLGRLEEIVQKMEKGDLALEESLKLFEEGVKLSRECHQRLNEAESKVKLLMSVGADGQPVTTDFTSEEN
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 8414

http://purl.uniprot.org/uniprot/Q6MR96#attribution-184D7E16AE095AF4A02481257D8AED90
manual: true
evidence: ECO_0000255
source: MF_00337

Q6MQD7
type: Protein
reviewed: true
created: 2005-09-13
modified: 2023-06-28
version: 87
mnemonic: FLGI_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP4DE3960BC5B5D52E
alternative name: SIPC3519A70475DC3F9
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP0105D6409344534D
annotation: SIPA6150D7AF332A800
annotation: SIPAC04C253A684153B
annotation: SIP92A62955496BBCA1
annotation: SIP77BCCB7518DBA6F4
annotation: PRO_0000041783
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/975
classified with: http://purl.uniprot.org/keywords/574
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/732
classified with: GO_0009428
classified with: GO_0030288
classified with: GO_0005198
classified with: GO_0071973
sequence: Q6MQD7-1
proteome: Chromosome

Q6MQD7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1706
type: Resource
database: eggNOG
comment: Bacteria

MF_00416
type: Resource
database: HAMAP
comment: FlgI
signature sequence match: HAMAP MF 00416 match 1

IPR001782
type: Resource
database: InterPro
comment: Flag_FlgI

PTHR30381
type: Resource
database: PANTHER
comment: FLAGELLAR P-RING PERIPLASMIC PROTEIN FLGI
signature sequence match: PANTHER PTHR30381 match 1

PTHR30381:SF0
type: Resource
database: PANTHER
comment: FLAGELLAR P-RING PROTEIN
signature sequence match: PANTHER PTHR30381:SF0 match 1

PF02119
type: Resource
database: Pfam
comment: FlgI
signature sequence match: Pfam PF02119 match 1

PR01010
type: Resource
database: PRINTS
comment: FLGPRINGFLGI

SIP4DE3960BC5B5D52E
type: Structured Name
full name: Flagellar P-ring protein

SIPC3519A70475DC3F9
type: Structured Name
full name: Basal body P-ring protein

flgI
type: Gene
locus name: Bd0535

SIP0105D6409344534D
type: Function Annotation
comment: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.

SIPA6150D7AF332A800
type: Subunit Annotation
comment: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

SIP92A62955496BBCA1
type: Similarity Annotation
comment: Belongs to the FlgI family.

22859178817369902tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MQD7-1

22859178817369902tt24
type: Position
type: ExactPosition
position: 24
reference: Q6MQD7-1

PRO_0000041783
type: Chain Annotation
comment: Flagellar P-ring protein
mass: 32626
range: 22859178817369902tt25tt335

22859178817369902tt25
type: Position
type: ExactPosition
position: 25
reference: Q6MQD7-1

22859178817369902tt335
type: Position
type: ExactPosition
position: 335
reference: Q6MQD7-1

Q6MQD7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
precursor: true
mass: 35265
value: MNKITNFLILSAVLFFSLIESANAARLKDIASIRGVRENQLIGYGIVVGLKGTGDGKNEFMSKSMVRMLDKLGMKLDNVDFASKNVAAVIVTATMPAFGKAGNPIDINVSAIGEASSLQGGTLLQTPLRAANEQVFAVAQGSIVIGGDGKDSHTTAGRIPNGATIERDMTADFSSRKMYRLTLINPDFTTAARSVLTINKELGGHYASAKDSGTIDIITPFAYENRGVELLATIESIEINPDMKARVVVNEKTGTIVIGDKVKISRVAISHGALSVKVGDGKKGAEEKVAVLDSGVSVGELVQALNKLGVSPKDLITILQSIKSAGALHGELEVL

http://purl.uniprot.org/uniprot/Q6MQD7#attribution-78CF714320801B24577C52D1F1ED629A
manual: true
evidence: ECO_0000255
source: MF_00416

Q6MQD1
type: Protein
reviewed: true
created: 2007-01-23
modified: 2023-09-13
version: 93
mnemonic: FLIW_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP2F487846192B35D6
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPCCF21D50601220F6
annotation: SIPD0A023C9D823E5DC
annotation: SIP65B4E53A54808414
annotation: SIP3B8A0B184F2951F4
annotation: PRO_0000272971
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1005
classified with: http://purl.uniprot.org/keywords/143
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/810
classified with: GO_0005737
classified with: GO_0044780
classified with: GO_0006417
sequence: MIISTSRFGQVELKQEDVLTFTEGLLGFADLRKFVLLDDPNDEIFAWLQSCEAPAIAFPVLEPELFAPQYKATLTKGDMEALKLTAQDKARYFSIVTIPDDPTLMTANLKAPVVVNIEARTARQCVLQDNNLAIREPIFTKLQQRVVQNPAVAIKNQSTGIDVATKLHVVRDAEL
proteome: Chromosome

Q6MQD1-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1699
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/2.30.290.10
type: Resource
database: Gene3D
comment: BH3618-like
signature sequence match: Gene3D 2.30.290.10 match 1

MF_01185
type: Resource
database: HAMAP
comment: FliW
signature sequence match: HAMAP MF 01185 match 1

IPR003775
type: Resource
database: InterPro
comment: Flagellar_assembly_factor_FliW

IPR024046
type: Resource
database: InterPro
comment: Flagellar_assmbl_FliW_dom_sf

PTHR39190
type: Resource
database: PANTHER
comment: FLAGELLAR ASSEMBLY FACTOR FLIW
signature sequence match: PANTHER PTHR39190 match 1

PTHR39190:SF1
type: Resource
database: PANTHER
comment: FLAGELLAR ASSEMBLY FACTOR FLIW
signature sequence match: PANTHER PTHR39190:SF1 match 1

PF02623
type: Resource
database: Pfam
comment: FliW
signature sequence match: Pfam PF02623 match 1

SSF141457
type: Resource
database: SUPFAM
comment: BH3618-like
signature sequence match: SUPFAM SSF141457 match 1

SIP2F487846192B35D6
type: Structured Name
full name: Flagellar assembly factor FliW

fliW
type: Gene
locus name: Bd0543

SIPCCF21D50601220F6
type: Function Annotation
comment: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.

SIPD0A023C9D823E5DC
type: Subunit Annotation
comment: Interacts with translational regulator CsrA and flagellin(s).

SIP3B8A0B184F2951F4
type: Similarity Annotation
comment: Belongs to the FliW family.

PRO_0000272971
type: Chain Annotation
comment: Flagellar assembly factor FliW
mass: 19485
range: 22859178817368366tt1tt175

22859178817368366tt1
type: Position
type: ExactPosition
position: 1
reference: MIISTSRFGQVELKQEDVLTFTEGLLGFADLRKFVLLDDPNDEIFAWLQSCEAPAIAFPVLEPELFAPQYKATLTKGDMEALKLTAQDKARYFSIVTIPDDPTLMTANLKAPVVVNIEARTARQCVLQDNNLAIREPIFTKLQQRVVQNPAVAIKNQSTGIDVATKLHVVRDAEL

22859178817368366tt175
type: Position
type: ExactPosition
position: 175
reference: MIISTSRFGQVELKQEDVLTFTEGLLGFADLRKFVLLDDPNDEIFAWLQSCEAPAIAFPVLEPELFAPQYKATLTKGDMEALKLTAQDKARYFSIVTIPDDPTLMTANLKAPVVVNIEARTARQCVLQDNNLAIREPIFTKLQQRVVQNPAVAIKNQSTGIDVATKLHVVRDAEL

MIISTSRFGQVELKQEDVLTFTEGLLGFADLRKFVLLDDPNDEIFAWLQSCEAPAIAFPVLEPELFAPQYKATLTKGDMEALKLTAQDKARYFSIVTIPDDPTLMTANLKAPVVVNIEARTARQCVLQDNNLAIREPIFTKLQQRVVQNPAVAIKNQSTGIDVATKLHVVRDAEL
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 19485

http://purl.uniprot.org/uniprot/Q6MQD1#attribution-87C8224142DBB8BA44DFAAD3B17F0A64
manual: true
evidence: ECO_0000255
source: MF_01185

Q6MJL7
type: Protein
reviewed: true
created: 2005-08-30
modified: 2023-09-13
version: 105
mnemonic: FMT_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPB847825D2C1252D7
enzyme: http://purl.uniprot.org/enzyme/2.1.2.9
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP7DC4125208D8BBD1
annotation: SIP4D66599E90896F98
annotation: SIP3653712ECDD7F249
annotation: PRO_0000082922
annotation: SIP793B551F22DB30D0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: GO_0004479
sequence: Q6MJL7-1
proteome: Chromosome

Q6MJL7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0223
type: Resource
database: eggNOG
comment: Bacteria

cd08646
type: Resource
database: CDD
comment: FMT_core_Met-tRNA-FMT_N
signature sequence match: CDD cd08646 match 1

cd08704
type: Resource
database: CDD
comment: Met_tRNA_FMT_C
signature sequence match: CDD cd08704 match 1

MF_00182
type: Resource
database: HAMAP
comment: Formyl_trans
signature sequence match: HAMAP MF 00182 match 1

IPR005794
type: Resource
database: InterPro
comment: Fmt

IPR005793
type: Resource
database: InterPro
comment: Formyl_trans_C

IPR002376
type: Resource
database: InterPro
comment: Formyl_transf_N

IPR036477
type: Resource
database: InterPro
comment: Formyl_transf_N_sf

IPR001555
type: Resource
database: InterPro
comment: GART_AS

IPR044135
type: Resource
database: InterPro
comment: Met-tRNA-FMT_C

IPR041711
type: Resource
database: InterPro
comment: Met-tRNA-FMT_N

TIGR00460
type: Resource
database: NCBIfam
comment: fmt
signature sequence match: NCBIfam TIGR00460 match 1

PTHR11138
type: Resource
database: PANTHER
comment: METHIONYL-TRNA FORMYLTRANSFERASE
signature sequence match: PANTHER PTHR11138 match 1

PTHR11138:SF5
type: Resource
database: PANTHER
comment: METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11138:SF5 match 1

PF02911
type: Resource
database: Pfam
comment: Formyl_trans_C
signature sequence match: Pfam PF02911 match 1

PF00551
type: Resource
database: Pfam
comment: Formyl_trans_N
signature sequence match: Pfam PF00551 match 1

SSF53328
type: Resource
database: SUPFAM
comment: Formyltransferase
signature sequence match: SUPFAM SSF53328 match 1

PS00373
type: Resource
database: PROSITE
comment: GART
signature sequence match: PROSITE PS00373 match 1

SIPB847825D2C1252D7
type: Structured Name
full name: Methionyl-tRNA formyltransferase
ec name: 2.1.2.9

fmt
type: Gene
locus name: Bd2757

SIP7DC4125208D8BBD1
type: Function Annotation
comment: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.

SIP3653712ECDD7F249
type: Similarity Annotation
comment: Belongs to the Fmt family.

PRO_0000082922
type: Chain Annotation
comment: Methionyl-tRNA formyltransferase
mass: 34442
range: 22859178700453678tt1tt318

22859178700453678tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MJL7-1

22859178700453678tt318
type: Position
type: ExactPosition
position: 318
reference: Q6MJL7-1

22859178700453678tt114
type: Position
type: ExactPosition
position: 114
reference: Q6MJL7-1

22859178700453678tt117
type: Position
type: ExactPosition
position: 117
reference: Q6MJL7-1

Q6MJL7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 34442
value: MSKVRVCFLGTPEFAVTSLKALLSDEHFEVVGVVTQPDRPAGRKLQLTPSPVKALAQAHNLKVLAPESLKANPLMLQEIKTWGAEVAVVVAFGQILTQEFLDSFRFGCVNVHGSVLPRWRGAAPIQRAIEAGDVESGVTLQKMVKKLDAGDIIGIRRVKITPDMNALQLHDVLAQLGAELLQVELMDYVRGNLAPTPQDESKVTLAKKIEKMESQIDWSTSAKAIDGKIRGFVYGPGTYTFLQGKKLKLHRATVTRDGGSIGSAKPGTITAVHEDHISVATGDGVLQLFEVQPESRNRMAIADFLKGHALKVGDQLGV

http://purl.uniprot.org/uniprot/Q6MJL7#attribution-7ADB9D678307BD581F4CF2062C7F6356
manual: true
evidence: ECO_0000255
source: MF_00182

Q6MI74
type: Protein
reviewed: true
created: 2006-12-12
modified: 2023-06-28
version: 103
mnemonic: FOLD_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPB0E7861556C8069B
domain: SIP48F851C727976C5B
domain: SIP7FDA6903BF270483
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPF543B54AC9875004
annotation: SIP66FB30BAACA20C8F
annotation: SIPE2756835D61EEFBC
annotation: SIP0B79236D1573EEF1
annotation: SIPD0B094A288367AEF
annotation: SIP6FB00376D61BA55F
annotation: PRO_0000268279
annotation: SIP4991C22F8645170A
annotation: SIP7746F1E59FDCA30E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/368
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/511
classified with: http://purl.uniprot.org/keywords/521
classified with: http://purl.uniprot.org/keywords/554
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/658
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004477
classified with: GO_0004488
classified with: GO_0000105
classified with: GO_0009086
classified with: GO_0006164
classified with: GO_0035999
sequence: Q6MI74-1
proteome: Chromosome

Q6MI74-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0190
type: Resource
database: eggNOG
comment: Bacteria

cd01080
type: Resource
database: CDD
comment: NAD_bind_m-THF_DH_Cyclohyd
signature sequence match: CDD cd01080 match 1

http://purl.uniprot.org/gene3d/3.40.50.10860
type: Resource
database: Gene3D
comment: Leucine Dehydrogenase, chain A, domain 1
signature sequence match: Gene3D 3.40.50.10860 match 1

MF_01576
type: Resource
database: HAMAP
comment: THF_DHG_CYH
signature sequence match: HAMAP MF 01576 match 1

IPR046346
type: Resource
database: InterPro
comment: Aminoacid_DH-like_N_sf

IPR000672
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase

IPR020630
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_cat_dom

IPR020867
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_CS

IPR020631
type: Resource
database: InterPro
comment: THF_DH/CycHdrlase_NAD-bd_dom

PTHR48099:SF5
type: Resource
database: PANTHER
comment: C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC
signature sequence match: PANTHER PTHR48099:SF5 match 1

PTHR48099
type: Resource
database: PANTHER
comment: C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED
signature sequence match: PANTHER PTHR48099 match 1

PF00763
type: Resource
database: Pfam
comment: THF_DHG_CYH
signature sequence match: Pfam PF00763 match 1

PF02882
type: Resource
database: Pfam
comment: THF_DHG_CYH_C
signature sequence match: Pfam PF02882 match 1

PR00085
type: Resource
database: PRINTS
comment: THFDHDRGNASE

SSF53223
type: Resource
database: SUPFAM
comment: Aminoacid dehydrogenase-like, N-terminal domain
signature sequence match: SUPFAM SSF53223 match 1

PS00767
type: Resource
database: PROSITE
comment: THF_DHG_CYH_2
signature sequence match: PROSITE PS00767 match 1

SIPB0E7861556C8069B
type: Structured Name
full name: Bifunctional protein FolD

SIP1DCE05B86FF5482A
type: Structured Name
full name: Methylenetetrahydrofolate dehydrogenase
ec name: 1.5.1.5

SIPC5E9CCE6F8486257
type: Structured Name
full name: Methenyltetrahydrofolate cyclohydrolase
ec name: 3.5.4.9

folD
type: Gene
locus name: Bd3295

SIPF543B54AC9875004
type: Function Annotation
comment: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.

SIPD0B094A288367AEF
type: Subunit Annotation
comment: Homodimer.

SIP6FB00376D61BA55F
type: Similarity Annotation
comment: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

PRO_0000268279
type: Chain Annotation
comment: Bifunctional protein FolD
mass: 30891
range: 22859178682299438tt1tt288

22859178682299438tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MI74-1

22859178682299438tt288
type: Position
type: ExactPosition
position: 288
reference: Q6MI74-1

22859178682299438tt165
type: Position
type: ExactPosition
position: 165
reference: Q6MI74-1

22859178682299438tt167
type: Position
type: ExactPosition
position: 167
reference: Q6MI74-1

22859178682299438tt190
type: Position
type: ExactPosition
position: 190
reference: Q6MI74-1

Q6MI74-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 30891
value: MVLILDGKEVAKEVRASLVPRVAKFKETYGRAPQLSVVIVGDDKASHVYVKNKKIACEKIGMTSTIHTLPAETTQSELNQILSKLNNDNGVDGILVQFPLPKHLSSDEVLKLVSAEKDADGLTYESLGYFFAGKPLVSPCTPAGVMEILKHYRIPVEGKKAVVVGRSNIVGKPMALLLTEANATVTLCHSKTSNMSELTKQADLVVVAAGKARLLGKEDFKKDAIVIDVGMHGSGQGGKLCGDVRFEELDGWAKAATPVPGGVGPMTIAMLLKNTCQLAEQRARDPQF

http://purl.uniprot.org/uniprot/Q6MI74#attribution-F069A5E3914EDBC44119710B6922B871
manual: true
evidence: ECO_0000255
source: MF_01576

Q6ML45
type: Protein
reviewed: true
created: 2006-03-21
modified: 2023-09-13
version: 116
mnemonic: FPG_BDEBA
citation: http://purl.uniprot.org/citations/14752164
conflicting sequence: SIP1D4B6D3BC12FD9FE
recommended name: SIPD6AF3A189A51AB01
alternative name: SIP3F600CAA6F280C6D
enzyme: http://purl.uniprot.org/enzyme/3.2.2.23
enzyme: http://purl.uniprot.org/enzyme/4.2.99.18
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPAF8EC9BE292A12C5
annotation: SIP84CC03AE80408852
annotation: SIPCD1FB6A766D70F28
annotation: SIP116888E958E547C7
annotation: SIPC120A8BAF12CB87F
annotation: SIP2279C0FDC4BE7EFF
annotation: SIP4807799EB6E96DB1
annotation: SIP0A13433FF7055310
annotation: PRO_0000228418
annotation: SIPDC2E35A59936B7AA
annotation: SIP88106F88E70598FC
annotation: SIP9F4A69AC1FC0B125
annotation: SIP08682D24620DFA30
annotation: SIPF6BADDA03275FB8D
annotation: SIPCBF6FFFEE1EF38FB
annotation: SIPC46A7F9B2A848B32
annotation: SIP18B2FD38009CE2E1
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/326
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/511
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/863
classified with: GO_0140078
classified with: GO_0003684
classified with: GO_0008534
classified with: GO_0008270
classified with: GO_0006284
sequence: Q6ML45-1
proteome: Chromosome

Q6ML45-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

EMBL CAE80012.1
comment: Different initiation.

COG0266
type: Resource
database: eggNOG
comment: Bacteria

cd08966
type: Resource
database: CDD
comment: EcFpg-like_N
signature sequence match: CDD cd08966 match 1

http://purl.uniprot.org/gene3d/3.20.190.10
type: Resource
database: Gene3D
comment: MutM-like, N-terminal
signature sequence match: Gene3D 3.20.190.10 match 1

MF_00103
type: Resource
database: HAMAP
comment: Fapy_DNA_glycosyl
signature sequence match: HAMAP MF 00103 match 1

IPR015886
type: Resource
database: InterPro
comment: DNA_glyclase/AP_lyase_DNA-bd

IPR015887
type: Resource
database: InterPro
comment: DNA_glyclase_Znf_dom_DNA_BS

IPR020629
type: Resource
database: InterPro
comment: Formamido-pyr_DNA_Glyclase

IPR012319
type: Resource
database: InterPro
comment: FPG_cat

IPR035937
type: Resource
database: InterPro
comment: MutM-like_N-ter

IPR010979
type: Resource
database: InterPro
comment: Ribosomal_S13-like_H2TH

IPR000214
type: Resource
database: InterPro
comment: Znf_DNA_glyclase/AP_lyase

IPR010663
type: Resource
database: InterPro
comment: Znf_FPG/IleRS

TIGR00577
type: Resource
database: NCBIfam
comment: fpg
signature sequence match: NCBIfam TIGR00577 match 1

PTHR22993
type: Resource
database: PANTHER
comment: FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE
signature sequence match: PANTHER PTHR22993 match 1

PTHR22993:SF9
type: Resource
database: PANTHER
comment: FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE
signature sequence match: PANTHER PTHR22993:SF9 match 1

PF01149
type: Resource
database: Pfam
comment: Fapy_DNA_glyco
signature sequence match: Pfam PF01149 match 1

PF06831
type: Resource
database: Pfam
comment: H2TH
signature sequence match: Pfam PF06831 match 1

PF06827
type: Resource
database: Pfam
comment: zf-FPG_IleRS
signature sequence match: Pfam PF06827 match 1

SM00898
type: Resource
database: SMART
comment: Fapy_DNA_glyco
signature sequence match: SMART SM00898 match 1

SM01232
type: Resource
database: SMART
comment: H2TH
signature sequence match: SMART SM01232 match 1

SSF81624
type: Resource
database: SUPFAM
comment: N-terminal domain of MutM-like DNA repair proteins
signature sequence match: SUPFAM SSF81624 match 1

SSF46946
type: Resource
database: SUPFAM
comment: S13-like H2TH domain
signature sequence match: SUPFAM SSF46946 match 1

PS51068
type: Resource
database: PROSITE
comment: FPG_CAT
signature sequence match: PROSITE PS51068 match 1

PS01242
type: Resource
database: PROSITE
comment: ZF_FPG_1
signature sequence match: PROSITE PS01242 match 1

PS51066
type: Resource
database: PROSITE
comment: ZF_FPG_2
signature sequence match: PROSITE PS51066 match 1

SIPD6AF3A189A51AB01
type: Structured Name
full name: Formamidopyrimidine-DNA glycosylase
short name: Fapy-DNA glycosylase
ec name: 3.2.2.23

SIP3F600CAA6F280C6D
type: Structured Name
full name: DNA-(apurinic or apyrimidinic site) lyase MutM
short name: AP lyase MutM
ec name: 4.2.99.18

mutM
type: Gene
alternative label: fpg
locus name: Bd2176

SIPAF8EC9BE292A12C5
type: Function Annotation
comment: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

SIP116888E958E547C7
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIPC120A8BAF12CB87F
type: Subunit Annotation
comment: Monomer.

SIP2279C0FDC4BE7EFF
type: Similarity Annotation
comment: Belongs to the FPG family.

SIP0A13433FF7055310
type: Initiator Methionine Annotation
comment: Removed
range: 22859178732434734tt1tt1

22859178732434734tt1
type: Position
type: ExactPosition
position: 1
reference: Q6ML45-1

PRO_0000228418
type: Chain Annotation
comment: Formamidopyrimidine-DNA glycosylase
mass: 29994
range: 22859178732434734tt2tt270

22859178732434734tt2
type: Position
type: ExactPosition
position: 2
reference: Q6ML45-1

22859178732434734tt270
type: Position
type: ExactPosition
position: 270
reference: Q6ML45-1

SIPDC2E35A59936B7AA
type: Zinc Finger Annotation
comment: FPG-type
range: 22859178732434734tt236tt270

22859178732434734tt236
type: Position
type: ExactPosition
position: 236
reference: Q6ML45-1

SIP88106F88E70598FC
type: Active Site Annotation
comment: Schiff-base intermediate with DNA
range: 22859178732434734tt2tt2

SIP9F4A69AC1FC0B125
type: Active Site Annotation
comment: Proton donor
range: 22859178732434734tt3tt3

22859178732434734tt3
type: Position
type: ExactPosition
position: 3
reference: Q6ML45-1

SIP08682D24620DFA30
type: Active Site Annotation
comment: Proton donor; for beta-elimination activity
range: 22859178732434734tt59tt59

22859178732434734tt59
type: Position
type: ExactPosition
position: 59
reference: Q6ML45-1

SIPF6BADDA03275FB8D
type: Active Site Annotation
comment: Proton donor; for delta-elimination activity
range: 22859178732434734tt260tt260

22859178732434734tt260
type: Position
type: ExactPosition
position: 260
reference: Q6ML45-1

22859178732434734tt91
type: Position
type: ExactPosition
position: 91
reference: Q6ML45-1

22859178732434734tt110
type: Position
type: ExactPosition
position: 110
reference: Q6ML45-1

22859178732434734tt151
type: Position
type: ExactPosition
position: 151
reference: Q6ML45-1

Q6ML45-1
type: Simple Sequence
modified: 2007-01-23
version: 3
mass: 30125
value: MPELPEVEVVRRGLETILKDQPILEKVELMRKDLREPIPAKKISTLVGQPLTSIERRAKYLLLWTPKGAMLSHLGMTGTWRVAVPGDERLHDHIYLHFSGDLRLAYRDPRRFGCFDFVQDPLKHPKLADLGPEPLEAEFNGPLLWEKLRGKDVALKVALMDQKVVVGVGNIYASEALFAAGIKPTLPARKLSLERASLLVGEIKKILSQSIKAGGSSISDFAQASGESGYFQTSFRVYGRDKEPCVTCGQQVKSKVLGGRNTFWCSRCQK

http://purl.uniprot.org/uniprot/Q6ML45#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/Q6ML45#attribution-67071DA3101E9B1E15623043D728FA9D
manual: true
evidence: ECO_0000255
source: MF_00103

http://purl.uniprot.org/uniprot/Q6ML45#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

Q6MLJ0
type: Protein
reviewed: true
created: 2021-09-29
modified: 2023-06-28
version: 79
mnemonic: FPN_BDEBA
citation: http://purl.uniprot.org/citations/14752164
citation: http://purl.uniprot.org/citations/26608034
citation: http://purl.uniprot.org/citations/26461048
citation: http://purl.uniprot.org/citations/30082682
recommended name: SIP91D3114A9BF52D69
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP1BC847433B1B49FF
annotation: SIPFA122E1B0C702EB9
annotation: SIP002313942260B865
annotation: SIP8F7BB7F2DB433520
annotation: PRO_0000453803
annotation: SIP1BC0ED94BB2F291B
annotation: SIP9A9BEFCC1A1AECE1
annotation: SIP2FFE0FFC6CD9BB92
annotation: SIPFABECD52EABE8A76
annotation: SIP2B6D837B72A79FF8
annotation: SIP23F2822F0373AEC3
annotation: SIP55F759A1CB736D7C
annotation: SIPF3345BE5B9EBD46F
annotation: SIPAF1B3EDFD9CC18BC
annotation: SIP4D4BE43807CEBA26
annotation: SIPE3026C23ADE65B2F
annotation: SIPC1EC162B705F3DE2
annotation: SIP09F05394CA446782
annotation: SIP06550F5AEA6D80F3
annotation: SIP68E860C3DB14914E
annotation: SIP2B96C79C775573E4
annotation: SIPE75F4B3622A33345
annotation: SIP1854A317CD9F2DCA
annotation: SIPBE192708708C6C37
annotation: SIP01AC92FB8DBB68F0
annotation: SIPF6422EE5B8E098B3
annotation: SIP304A687FF4328FC4
annotation: SIP34774FC068E5B7A3
annotation: SIP3E3D7E2AD9AD6D0E
annotation: SIPCDDA81C722A6852B
annotation: SIPD0791561E71B309D
annotation: SIP3A6C0CDB8E0218EF
annotation: SIPEFC0D4A04973642B
annotation: SIP95C34B30F4AF60B5
annotation: SIP1C3F63FCB4AB9D8F
annotation: SIP973BE8E6B438F644
annotation: SIPBC4073202D439552
annotation: SIP93C220B52A1526A2
annotation: SIPC743D4D51268E0FF
annotation: SIPED3FB543B1488498
annotation: SIP2E9930D9913F91D4
annotation: SIP83650E48C9FFF841
annotation: SIP0CD9FE27575A598E
annotation: SIP2EC5E0A0BE7C3FAF
annotation: SIPB5FFBB012F7A26CB
annotation: SIP1790C0C7B3038A7F
annotation: SIPA9F3EF1A9686DBEC
annotation: SIP1B63CE9FB6E4E270
annotation: SIPECB32A8711D93D16
annotation: SIP16856EA85C17E832
annotation: SIP05FC86459FBA7AD8
annotation: SIP1836C645D4399144
annotation: SIPDD89808D88049EFD
annotation: SIP8E5FB2A848AC6C17
annotation: SIP2F07D25F1B2C0093
annotation: SIP938A393610FD26AD
annotation: SIP3FDBFEB4A2604DEF
annotation: SIP7071E10D3EA95432
annotation: SIP52A25A0BAB67ED12
annotation: SIP5558E940972542C0
annotation: SIP7BBB236E70083C50
annotation: SIP59B1B6C7F1B3F070
annotation: SIPDB26F85DEEF41B4C
annotation: SIP84C131D6549F5395
annotation: SIPC8FA74973111840B
existence: Evidence at Protein Level Existence
classified with: http://purl.uniprot.org/keywords/2
classified with: http://purl.uniprot.org/keywords/1003

Q6MLJ0-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

Q6MLJ0-citation-26608034
type: Citation Statement
scope: FUNCTION
scope: MUTAGENESIS OF ASP-24; ASP-28; ASP-162; GLU-166; HIS-261 AND ARG-348

Q6MLJ0-citation-26461048
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 1-433 IN COMPLEX WITH IRON
scope: SUBCELLULAR LOCATION
scope: MUTAGENESIS OF ASP-24 AND ASN-196

Q6MLJ0-citation-30082682
type: Citation Statement
scope: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS) OF 1-433
scope: COFACTOR
scope: MUTAGENESIS OF ASP-24; GLN-84; ASN-196 AND GLU-203

5AYM
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 3.00
chain sequence mapping: PDB 5AYM tt1tt433

PDB 5AYM tt1tt433
chain: A=1-433

5AYN
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 2.20
chain sequence mapping: PDB 5AYN tt1tt433

PDB 5AYN tt1tt433
chain: A=1-433

5AYO
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 3.30
chain sequence mapping: PDB 5AYO tt1tt433

PDB 5AYO tt1tt433
chain: A=1-433

6BTX
type: Structure Resource
database: PDB
method: X-Ray Crystallography
resolution: 3.20
chain sequence mapping: PDB 6BTX tt1tt433

PDB 6BTX tt1tt433
chain: A=1-433

2.A.100.2.1
type: Resource
database: TCDB
comment: the ferroportin (fpn) family

cd17480
type: Resource
database: CDD
comment: MFS_SLC40A1_like
signature sequence match: CDD cd17480 match 1

http://purl.uniprot.org/gene3d/1.20.1250.20
type: Resource
database: Gene3D
comment: MFS general substrate transporter like domains
signature sequence match: Gene3D 1.20.1250.20 match 1

IPR009716
type: Resource
database: InterPro
comment: Ferroportin-1

IPR036259
type: Resource
database: InterPro
comment: MFS_trans_sf

PTHR11660
type: Resource
database: PANTHER
comment: SOLUTE CARRIER FAMILY 40 MEMBER
signature sequence match: PANTHER PTHR11660 match 1

PTHR11660:SF57
type: Resource
database: PANTHER
comment: SOLUTE CARRIER FAMILY 40 PROTEIN
signature sequence match: PANTHER PTHR11660:SF57 match 1

PF06963
type: Resource
database: Pfam
comment: FPN1
signature sequence match: Pfam PF06963 match 1
signature sequence match: Pfam PF06963 match 2

SSF103473
type: Resource
database: SUPFAM
comment: MFS general substrate transporter
signature sequence match: SUPFAM SSF103473 match 1

SIP91D3114A9BF52D69
type: Structured Name
full name: Ferreportin
short name: Fpn

slc39
type: Gene
locus name: Bd2019

SIP1BC847433B1B49FF
type: Function Annotation
comment: Iron transpoter that exports Fe(2+) from the cell. Also binds to Co(2+) and Ni(2+). May act as a multivalent divalent metal transporter (PubMed:26608034). The transporter is composed of 12 transmembrane (TM) helices organized into N-terminal (TM1-6) and C-terminal (TM7-12) domains. The substrate-binding site is formed at the interface of the two domains and is alternately accessible from either side of the membrane. The transport cycle is viewed as a series of ligand-induced conformational changes that include open outward and open inward states (PubMed:26461048, PubMed:30082682).

SIPFA122E1B0C702EB9
type: Cofactor Annotation
comment: The cofactor facilitates a conformational change critical to the transport cycle. The binding of Ca2+ from extracellular fluid activates the transporter by triggering a conformational change that enables the transition from the open outward to open inward states.
cofactor: CHEBI_29108

SIP8F7BB7F2DB433520
type: Similarity Annotation
comment: Belongs to the ferroportin (FP) (TC 2.A.100) family.

PRO_0000453803
type: Chain Annotation
comment: Ferreportin
mass: 48363
range: 22859178733875246tt1tt440

22859178733875246tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MLJ0-1

22859178733875246tt440
type: Position
type: ExactPosition
position: 440
reference: Q6MLJ0-1

SIP1BC0ED94BB2F291B
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt1tt8

22859178733875246tt8
type: Position
type: ExactPosition
position: 8
reference: Q6MLJ0-1

SIP9A9BEFCC1A1AECE1
type: Transmembrane Annotation
comment: Helical; Name=1
range: 22859178733875246tt9tt38

22859178733875246tt9
type: Position
type: ExactPosition
position: 9
reference: Q6MLJ0-1

22859178733875246tt38
type: Position
type: ExactPosition
position: 38
reference: Q6MLJ0-1

SIP2FFE0FFC6CD9BB92
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt39tt42

22859178733875246tt39
type: Position
type: ExactPosition
position: 39
reference: Q6MLJ0-1

22859178733875246tt42
type: Position
type: ExactPosition
position: 42
reference: Q6MLJ0-1

SIPFABECD52EABE8A76
type: Transmembrane Annotation
comment: Helical; Name=2
range: 22859178733875246tt43tt69

22859178733875246tt43
type: Position
type: ExactPosition
position: 43
reference: Q6MLJ0-1

22859178733875246tt69
type: Position
type: ExactPosition
position: 69
reference: Q6MLJ0-1

SIP2B6D837B72A79FF8
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt70tt72

22859178733875246tt70
type: Position
type: ExactPosition
position: 70
reference: Q6MLJ0-1

22859178733875246tt72
type: Position
type: ExactPosition
position: 72
reference: Q6MLJ0-1

SIP23F2822F0373AEC3
type: Transmembrane Annotation
comment: Helical; Name=3
range: 22859178733875246tt73tt103

22859178733875246tt73
type: Position
type: ExactPosition
position: 73
reference: Q6MLJ0-1

22859178733875246tt103
type: Position
type: ExactPosition
position: 103
reference: Q6MLJ0-1

SIP55F759A1CB736D7C
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt104tt109

22859178733875246tt104
type: Position
type: ExactPosition
position: 104
reference: Q6MLJ0-1

22859178733875246tt109
type: Position
type: ExactPosition
position: 109
reference: Q6MLJ0-1

SIPF3345BE5B9EBD46F
type: Transmembrane Annotation
comment: Helical; Name=4
range: 22859178733875246tt110tt145

22859178733875246tt110
type: Position
type: ExactPosition
position: 110
reference: Q6MLJ0-1

22859178733875246tt145
type: Position
type: ExactPosition
position: 145
reference: Q6MLJ0-1

SIPAF1B3EDFD9CC18BC
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt146tt147

22859178733875246tt146
type: Position
type: ExactPosition
position: 146
reference: Q6MLJ0-1

22859178733875246tt147
type: Position
type: ExactPosition
position: 147
reference: Q6MLJ0-1

SIP4D4BE43807CEBA26
type: Transmembrane Annotation
comment: Helical; Name=5
range: 22859178733875246tt148tt176

22859178733875246tt148
type: Position
type: ExactPosition
position: 148
reference: Q6MLJ0-1

22859178733875246tt176
type: Position
type: ExactPosition
position: 176
reference: Q6MLJ0-1

SIPE3026C23ADE65B2F
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt177tt186

22859178733875246tt177
type: Position
type: ExactPosition
position: 177
reference: Q6MLJ0-1

22859178733875246tt186
type: Position
type: ExactPosition
position: 186
reference: Q6MLJ0-1

SIPC1EC162B705F3DE2
type: Transmembrane Annotation
comment: Helical; Name=6
range: 22859178733875246tt187tt213

22859178733875246tt187
type: Position
type: ExactPosition
position: 187
reference: Q6MLJ0-1

22859178733875246tt213
type: Position
type: ExactPosition
position: 213
reference: Q6MLJ0-1

SIP09F05394CA446782
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt214tt242

22859178733875246tt214
type: Position
type: ExactPosition
position: 214
reference: Q6MLJ0-1

22859178733875246tt242
type: Position
type: ExactPosition
position: 242
reference: Q6MLJ0-1

SIP06550F5AEA6D80F3
type: Transmembrane Annotation
comment: Helical; Name=7
range: 22859178733875246tt243tt271

22859178733875246tt243
type: Position
type: ExactPosition
position: 243
reference: Q6MLJ0-1

22859178733875246tt271
type: Position
type: ExactPosition
position: 271
reference: Q6MLJ0-1

SIP68E860C3DB14914E
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt272tt276

22859178733875246tt272
type: Position
type: ExactPosition
position: 272
reference: Q6MLJ0-1

22859178733875246tt276
type: Position
type: ExactPosition
position: 276
reference: Q6MLJ0-1

SIP2B96C79C775573E4
type: Transmembrane Annotation
comment: Helical; Name=8
range: 22859178733875246tt277tt304

22859178733875246tt277
type: Position
type: ExactPosition
position: 277
reference: Q6MLJ0-1

22859178733875246tt304
type: Position
type: ExactPosition
position: 304
reference: Q6MLJ0-1

SIPE75F4B3622A33345
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt305tt306

22859178733875246tt305
type: Position
type: ExactPosition
position: 305
reference: Q6MLJ0-1

22859178733875246tt306
type: Position
type: ExactPosition
position: 306
reference: Q6MLJ0-1

SIP1854A317CD9F2DCA
type: Transmembrane Annotation
comment: Helical; Name=9
range: 22859178733875246tt307tt329

22859178733875246tt307
type: Position
type: ExactPosition
position: 307
reference: Q6MLJ0-1

22859178733875246tt329
type: Position
type: ExactPosition
position: 329
reference: Q6MLJ0-1

SIPBE192708708C6C37
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt330tt335

22859178733875246tt330
type: Position
type: ExactPosition
position: 330
reference: Q6MLJ0-1

22859178733875246tt335
type: Position
type: ExactPosition
position: 335
reference: Q6MLJ0-1

SIP01AC92FB8DBB68F0
type: Transmembrane Annotation
comment: Helical; Name=10
range: 22859178733875246tt336tt365

22859178733875246tt336
type: Position
type: ExactPosition
position: 336
reference: Q6MLJ0-1

22859178733875246tt365
type: Position
type: ExactPosition
position: 365
reference: Q6MLJ0-1

SIPF6422EE5B8E098B3
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt366tt370

22859178733875246tt366
type: Position
type: ExactPosition
position: 366
reference: Q6MLJ0-1

22859178733875246tt370
type: Position
type: ExactPosition
position: 370
reference: Q6MLJ0-1

SIP304A687FF4328FC4
type: Transmembrane Annotation
comment: Helical; Name=11
range: 22859178733875246tt371tt395

22859178733875246tt371
type: Position
type: ExactPosition
position: 371
reference: Q6MLJ0-1

22859178733875246tt395
type: Position
type: ExactPosition
position: 395
reference: Q6MLJ0-1

SIP34774FC068E5B7A3
type: Topological Domain Annotation
comment: Extracellular
range: 22859178733875246tt396tt398

22859178733875246tt396
type: Position
type: ExactPosition
position: 396
reference: Q6MLJ0-1

22859178733875246tt398
type: Position
type: ExactPosition
position: 398
reference: Q6MLJ0-1

SIP3E3D7E2AD9AD6D0E
type: Transmembrane Annotation
comment: Helical; Name=12
range: 22859178733875246tt399tt424

22859178733875246tt399
type: Position
type: ExactPosition
position: 399
reference: Q6MLJ0-1

22859178733875246tt424
type: Position
type: ExactPosition
position: 424
reference: Q6MLJ0-1

SIPCDDA81C722A6852B
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178733875246tt425tt440

22859178733875246tt425
type: Position
type: ExactPosition
position: 425
reference: Q6MLJ0-1

22859178733875246tt24
type: Position
type: ExactPosition
position: 24
reference: Q6MLJ0-1

22859178733875246tt84
type: Position
type: ExactPosition
position: 84
reference: Q6MLJ0-1

22859178733875246tt196
type: Position
type: ExactPosition
position: 196
reference: Q6MLJ0-1

22859178733875246tt203
type: Position
type: ExactPosition
position: 203
reference: Q6MLJ0-1

SIP1C3F63FCB4AB9D8F
type: Mutagenesis Annotation
comment: Slows down the kinetics of iron transport, while not affecting the iron binding ability. Complete loss of calcium binding.
substitution: A
range: 22859178733875246tt24tt24

SIP973BE8E6B438F644
type: Mutagenesis Annotation
comment: No effect.
substitution: A
range: 22859178733875246tt28tt28

22859178733875246tt28
type: Position
type: ExactPosition
position: 28
reference: Q6MLJ0-1

SIPBC4073202D439552
type: Mutagenesis Annotation
comment: Complete loss of calcium binding.
substitution: E
range: 22859178733875246tt84tt84

SIP93C220B52A1526A2
type: Mutagenesis Annotation
comment: No effect.
substitution: A
range: 22859178733875246tt162tt162

22859178733875246tt162
type: Position
type: ExactPosition
position: 162
reference: Q6MLJ0-1

SIPC743D4D51268E0FF
type: Mutagenesis Annotation
comment: Slows down the kinetics of iron transport, while not affecting the iron binding ability.
substitution: A
range: 22859178733875246tt166tt166

22859178733875246tt166
type: Position
type: ExactPosition
position: 166
reference: Q6MLJ0-1

SIPED3FB543B1488498
type: Mutagenesis Annotation
comment: Reduces transport activity. Complete loss of calcium binding.
substitution: A
range: 22859178733875246tt196tt196

SIP2E9930D9913F91D4
type: Mutagenesis Annotation
comment: Complete loss of calcium binding.
substitution: A
range: 22859178733875246tt203tt203

SIP83650E48C9FFF841
type: Mutagenesis Annotation
comment: Complete loss of iron binding. Completely abolishes the transport ability.
substitution: D
range: 22859178733875246tt261tt261

22859178733875246tt261
type: Position
type: ExactPosition
position: 261
reference: Q6MLJ0-1

SIP0CD9FE27575A598E
type: Mutagenesis Annotation
comment: Complete loss of iron binding. Completely abolishes the transport ability.
substitution: M
range: 22859178733875246tt348tt348

22859178733875246tt348
type: Position
type: ExactPosition
position: 348
reference: Q6MLJ0-1

22859178733875246tt68
type: Position
type: ExactPosition
position: 68
reference: Q6MLJ0-1

22859178733875246tt107
type: Position
type: ExactPosition
position: 107
reference: Q6MLJ0-1

22859178733875246tt139
type: Position
type: ExactPosition
position: 139
reference: Q6MLJ0-1

22859178733875246tt141
type: Position
type: ExactPosition
position: 141
reference: Q6MLJ0-1

22859178733875246tt150
type: Position
type: ExactPosition
position: 150
reference: Q6MLJ0-1

22859178733875246tt151
type: Position
type: ExactPosition
position: 151
reference: Q6MLJ0-1

22859178733875246tt212
type: Position
type: ExactPosition
position: 212
reference: Q6MLJ0-1

22859178733875246tt215
type: Position
type: ExactPosition
position: 215
reference: Q6MLJ0-1

22859178733875246tt217
type: Position
type: ExactPosition
position: 217
reference: Q6MLJ0-1

22859178733875246tt236
type: Position
type: ExactPosition
position: 236
reference: Q6MLJ0-1

22859178733875246tt239
type: Position
type: ExactPosition
position: 239
reference: Q6MLJ0-1

22859178733875246tt251
type: Position
type: ExactPosition
position: 251
reference: Q6MLJ0-1

22859178733875246tt252
type: Position
type: ExactPosition
position: 252
reference: Q6MLJ0-1

22859178733875246tt255
type: Position
type: ExactPosition
position: 255
reference: Q6MLJ0-1

22859178733875246tt263
type: Position
type: ExactPosition
position: 263
reference: Q6MLJ0-1

22859178733875246tt334
type: Position
type: ExactPosition
position: 334
reference: Q6MLJ0-1

22859178733875246tt337
type: Position
type: ExactPosition
position: 337
reference: Q6MLJ0-1

22859178733875246tt368
type: Position
type: ExactPosition
position: 368
reference: Q6MLJ0-1

22859178733875246tt401
type: Position
type: ExactPosition
position: 401
reference: Q6MLJ0-1

22859178733875246tt402
type: Position
type: ExactPosition
position: 402
reference: Q6MLJ0-1

Q6MLJ0-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 48363
value: MKVQSLLRIETQLLLGRLLTRSGDQAWDFVVPFALLVIFPGKLQVAAFYYLIVKIGTFLLTPSSGKWIDTHPRIQVVKWGVWLQFFAILAGMVFFGMLDGLVRAGGRESWLLSVLFIALALSGVMASLGSQITDISVGNDLAPSLVAPEKLTHFNSWLRRIDLATEVGAPILAGALFAFHPEQLPLAGLFLIGLWNLVSFVPEYFLLRNVIQRSGLKIKVLTEAQSWKDTFHINLRGSFSDPIFWLILSYALLWLSVLSPHGVLLAAYLKDEMRLPETEIGLFRGLGAVFGLISTVSFPYLVRRLGLISSSRWHLGFQGVTLGIAVTAFAMGSTASVYVFLGCILLSRVGLYGFSNGEFELRQRLIPEGRRGELNSLSSLTTTSATLILFSAGSLLPQTEDFKYLVYVSLAAVLLANVVFIKWSSRQGVVTSGAAEPVES

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-1CCA98D2869C953437AC990C2C78B7CD
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/26461048

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-D4617194126C8834B756FD0E8009FAA1
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/26608034

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-7D96A558CA1D1DCF758BD327C8F3642D
manual: true
evidence: ECO_0000269
source: http://purl.uniprot.org/citations/30082682

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-F52EE6AC100CADDC16306AD8C4FAC932
manual: true
evidence: ECO_0000303
source: http://purl.uniprot.org/citations/26608034

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-412AAA1E1185BCDF2079B87BA1F4BAD7
manual: true
evidence: ECO_0000305

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-5FFF3707691D2E0B90B8E7415EC6EE34
manual: true
evidence: ECO_0000305
source: http://purl.uniprot.org/citations/26461048

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-79928B9F6E19135B31D79EAD73B7F3FA
manual: true
evidence: ECO_0007744
source: 5AYM

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-7D372474CD17AA91E3D00EC820A7EC0F
manual: true
evidence: ECO_0007744
source: 5AYN

http://purl.uniprot.org/uniprot/Q6MLJ0#attribution-3289CEAA7FA1EEDEA6278F8BF3F5D651
manual: true
evidence: ECO_0007744
source: 6BTX

Q6MLS7
type: Protein
reviewed: true
created: 2010-11-02
modified: 2023-09-13
version: 123
mnemonic: FTSH1_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP1C8B6557C9E8BD09
enzyme: http://purl.uniprot.org/enzyme/3.4.24.-
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPCE45EFD06C9ABF03
annotation: SIP4D5B8F48F6C0BB71
annotation: SIP20B9C679D024E5E9
annotation: SIP665624486AEFC8EC
annotation: SIP5161F4667E7F9B23
annotation: SIP3E987F1DCFD2751E
annotation: PRO_0000400330
annotation: SIP71AD827A82BF1E91
annotation: SIPCED9B5890A081A06
annotation: SIP65B584AE9C9F1DD1
annotation: SIP0FEE81488559AA2C
annotation: SIPD3B923ACFE783B0D
annotation: SIP221BF345707B5A43
annotation: SIPDE9631AED321F726
annotation: SIP7C40C9567A96BF0E
annotation: SIPDE10A121172168BE
annotation: SIP14F2661584926D66
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/482
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005886
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0004176
classified with: GO_0004222
classified with: GO_0008270
classified with: GO_0030163
classified with: GO_0006508
sequence: Q6MLS7-1
proteome: Chromosome

Q6MLS7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0465
type: Resource
database: eggNOG
comment: Bacteria

cd19501
type: Resource
database: CDD
comment: RecA-like_FtsH
signature sequence match: CDD cd19501 match 1

http://purl.uniprot.org/gene3d/1.20.58.760
type: Resource
database: Gene3D
comment: Peptidase M41
signature sequence match: Gene3D 1.20.58.760 match 1

MF_01458
type: Resource
database: HAMAP
comment: FtsH
signature sequence match: HAMAP MF 01458 match 1

IPR041569
type: Resource
database: InterPro
comment: AAA_lid_3

IPR003960
type: Resource
database: InterPro
comment: ATPase_AAA_CS

IPR005936
type: Resource
database: InterPro
comment: FtsH

IPR000642
type: Resource
database: InterPro
comment: Peptidase_M41

IPR037219
type: Resource
database: InterPro
comment: Peptidase_M41-like

TIGR01241
type: Resource
database: NCBIfam
comment: FtsH_fam
signature sequence match: NCBIfam TIGR01241 match 1

PTHR23076:SF97
type: Resource
database: PANTHER
comment: ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1
signature sequence match: PANTHER PTHR23076:SF97 match 1

PTHR23076
type: Resource
database: PANTHER
comment: METALLOPROTEASE M41 FTSH
signature sequence match: PANTHER PTHR23076 match 1

PF17862
type: Resource
database: Pfam
comment: AAA_lid_3
signature sequence match: Pfam PF17862 match 1

PF01434
type: Resource
database: Pfam
comment: Peptidase_M41
signature sequence match: Pfam PF01434 match 1

SSF140990
type: Resource
database: SUPFAM
comment: FtsH protease domain-like
signature sequence match: SUPFAM SSF140990 match 1

PS00674
type: Resource
database: PROSITE
comment: AAA
signature sequence match: PROSITE PS00674 match 1

SIP1C8B6557C9E8BD09
type: Structured Name
full name: ATP-dependent zinc metalloprotease FtsH 1
ec name: 3.4.24.-

ftsH1
type: Gene
locus name: Bd1928

SIPCE45EFD06C9ABF03
type: Function Annotation
comment: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.

SIP4D5B8F48F6C0BB71
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP20B9C679D024E5E9
type: Subunit Annotation
comment: Homohexamer.

SIP5161F4667E7F9B23
type: Similarity Annotation
comment: In the central section; belongs to the AAA ATPase family.

SIP3E987F1DCFD2751E
type: Similarity Annotation
comment: In the C-terminal section; belongs to the peptidase M41 family.

PRO_0000400330
type: Chain Annotation
comment: ATP-dependent zinc metalloprotease FtsH 1
mass: 70985
range: 22859178734466862tt1tt645

22859178734466862tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MLS7-1

22859178734466862tt645
type: Position
type: ExactPosition
position: 645
reference: Q6MLS7-1

SIP71AD827A82BF1E91
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178734466862tt1tt6

22859178734466862tt6
type: Position
type: ExactPosition
position: 6
reference: Q6MLS7-1

SIPCED9B5890A081A06
type: Transmembrane Annotation
comment: Helical
range: 22859178734466862tt7tt27

22859178734466862tt7
type: Position
type: ExactPosition
position: 7
reference: Q6MLS7-1

22859178734466862tt27
type: Position
type: ExactPosition
position: 27
reference: Q6MLS7-1

SIP65B584AE9C9F1DD1
type: Topological Domain Annotation
comment: Periplasmic
range: 22859178734466862tt28tt110

22859178734466862tt28
type: Position
type: ExactPosition
position: 28
reference: Q6MLS7-1

22859178734466862tt110
type: Position
type: ExactPosition
position: 110
reference: Q6MLS7-1

SIP0FEE81488559AA2C
type: Transmembrane Annotation
comment: Helical
range: 22859178734466862tt111tt131

22859178734466862tt111
type: Position
type: ExactPosition
position: 111
reference: Q6MLS7-1

22859178734466862tt131
type: Position
type: ExactPosition
position: 131
reference: Q6MLS7-1

SIPD3B923ACFE783B0D
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178734466862tt132tt645

22859178734466862tt132
type: Position
type: ExactPosition
position: 132
reference: Q6MLS7-1

22859178734466862tt426
type: Position
type: ExactPosition
position: 426
reference: Q6MLS7-1

22859178734466862tt203
type: Position
type: ExactPosition
position: 203
reference: Q6MLS7-1

22859178734466862tt210
type: Position
type: ExactPosition
position: 210
reference: Q6MLS7-1

22859178734466862tt425
type: Position
type: ExactPosition
position: 425
reference: Q6MLS7-1

22859178734466862tt429
type: Position
type: ExactPosition
position: 429
reference: Q6MLS7-1

22859178734466862tt501
type: Position
type: ExactPosition
position: 501
reference: Q6MLS7-1

SIP3BAF37F414AD6315
subclass of: CHEBI_29105
comment: catalytic

Q6MLS7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 70985
value: MRSTQKTLALWFFLIIMAVFLFQAYESKQQKAIADFNFSKFTEAVKAGEVATVTFRQDTSEVVGEMKPEFEKKYNGTHFSIVGNTQDEGYKFLQQHGITPNYERADNGGFFQSLLVNWLPLILIVAMFLFIMRQIQAGGGKAMSFGKSRARLLTEHKNRVTFKEVAGVDEAKEDLQEIVSFLKDPKKYTKLGGRIPKGVLLVGSPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQGKKNAPCLIFIDEIDAVGRHRGAGMGGGHDEREQTLNQLLVEMDGFESSEGVIMIAATNRPDVLDPALLRPGRFDRRVIVNKPDLKGREQILAVHMRKTPLGPDVDASKIARGTPGFSGADLENLVNEAALVAARSDKKYLEMEDFEKAKDKVTMGAERRSMVISDEDKKVTAYHEAGHTLVGKKLVGLDPIHKVTIIPRGMALGVTQTLPEKESVSLSKSKAENMIAFLFGGRAAEELIFKDITTGAGNDIERATEIARRMVCEWGMSKLGPLAYETRDNPVFMGMGYGNKSKEYSDAKAQEIDTEVEKIIKHGYDISIQILRDHQDALERLTQALLEYETIDGHEVDMLVNGAAVAEIEKYRNAKKDSNAAIMNAAEKKGSGDPVGNTGPVTI

http://purl.uniprot.org/uniprot/Q6MLS7#attribution-D6D0D75B0781770BD3C4CC615AC12BF1
manual: true
evidence: ECO_0000255
source: MF_01458

Q6MJV1
type: Protein
reviewed: true
created: 2010-11-02
modified: 2023-09-13
version: 121
mnemonic: FTSH2_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPAFF6AC4FB1AA5106
enzyme: http://purl.uniprot.org/enzyme/3.4.24.-
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP4BC3DBD22AD93BD0
annotation: SIP3CA9DD40645112B8
annotation: SIP16F8E88CE13F49D9
annotation: SIP350B902870648556
annotation: SIP1026BF3893729086
annotation: SIPF2ABECE534A68E5F
annotation: PRO_0000400329
annotation: SIP0F00DF64A2EB244D
annotation: SIP2E869CD97E988CE5
annotation: SIP08A2E8E5F593D8A0
annotation: SIPF9C69F85F63C1FDF
annotation: SIP130EE9C2F1AF7E65
annotation: SIPE485F162FB640970
annotation: SIP7D37D1314D3676DA
annotation: SIP797A51AFF8FB58E8
annotation: SIP9255C105D8D160D2
annotation: SIPC5E15699A93D259F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/997
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/482
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005886
classified with: GO_0005524
classified with: GO_0016887
classified with: GO_0004176
classified with: GO_0004222
classified with: GO_0008270
classified with: GO_0030163
classified with: GO_0006508
sequence: Q6MJV1-1
proteome: Chromosome

Q6MJV1-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

IPR011546
type: Resource
database: InterPro
comment: Pept_M41_FtsH_extracell

PTHR43655
type: Resource
database: PANTHER
comment: ATP-DEPENDENT PROTEASE
signature sequence match: PANTHER PTHR43655 match 1

PTHR43655:SF2
type: Resource
database: PANTHER
comment: ATP-DEPENDENT ZINC METALLOPROTEASE YME1L-RELATED
signature sequence match: PANTHER PTHR43655:SF2 match 1

PF06480
type: Resource
database: Pfam
comment: FtsH_ext
signature sequence match: Pfam PF06480 match 1

SIPAFF6AC4FB1AA5106
type: Structured Name
full name: ATP-dependent zinc metalloprotease FtsH 2
ec name: 3.4.24.-

ftsH2
type: Gene
locus name: Bd2667

SIP4BC3DBD22AD93BD0
type: Function Annotation
comment: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.

SIP3CA9DD40645112B8
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP16F8E88CE13F49D9
type: Subunit Annotation
comment: Homohexamer.

SIP1026BF3893729086
type: Similarity Annotation
comment: In the central section; belongs to the AAA ATPase family.

SIPF2ABECE534A68E5F
type: Similarity Annotation
comment: In the C-terminal section; belongs to the peptidase M41 family.

PRO_0000400329
type: Chain Annotation
comment: ATP-dependent zinc metalloprotease FtsH 2
mass: 67977
range: 22859178701107502tt1tt615

22859178701107502tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MJV1-1

22859178701107502tt615
type: Position
type: ExactPosition
position: 615
reference: Q6MJV1-1

SIP0F00DF64A2EB244D
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178701107502tt1tt7

22859178701107502tt7
type: Position
type: ExactPosition
position: 7
reference: Q6MJV1-1

SIP2E869CD97E988CE5
type: Transmembrane Annotation
comment: Helical
range: 22859178701107502tt8tt28

22859178701107502tt8
type: Position
type: ExactPosition
position: 8
reference: Q6MJV1-1

22859178701107502tt28
type: Position
type: ExactPosition
position: 28
reference: Q6MJV1-1

SIP08A2E8E5F593D8A0
type: Topological Domain Annotation
comment: Periplasmic
range: 22859178701107502tt29tt99

22859178701107502tt29
type: Position
type: ExactPosition
position: 29
reference: Q6MJV1-1

22859178701107502tt99
type: Position
type: ExactPosition
position: 99
reference: Q6MJV1-1

SIPF9C69F85F63C1FDF
type: Transmembrane Annotation
comment: Helical
range: 22859178701107502tt100tt120

22859178701107502tt100
type: Position
type: ExactPosition
position: 100
reference: Q6MJV1-1

22859178701107502tt120
type: Position
type: ExactPosition
position: 120
reference: Q6MJV1-1

SIP130EE9C2F1AF7E65
type: Topological Domain Annotation
comment: Cytoplasmic
range: 22859178701107502tt121tt615

22859178701107502tt121
type: Position
type: ExactPosition
position: 121
reference: Q6MJV1-1

22859178701107502tt419
type: Position
type: ExactPosition
position: 419
reference: Q6MJV1-1

22859178701107502tt195
type: Position
type: ExactPosition
position: 195
reference: Q6MJV1-1

22859178701107502tt202
type: Position
type: ExactPosition
position: 202
reference: Q6MJV1-1

22859178701107502tt418
type: Position
type: ExactPosition
position: 418
reference: Q6MJV1-1

22859178701107502tt422
type: Position
type: ExactPosition
position: 422
reference: Q6MJV1-1

22859178701107502tt495
type: Position
type: ExactPosition
position: 495
reference: Q6MJV1-1

SIP3BAF37F414AD6315
subclass of: CHEBI_29105
comment: catalytic

Q6MJV1-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 67977
value: MNEPNRNFFWIFFLILGIFWLQSVWFGSRTVQQIPYSQYESLVKQGDVQNLIVTENHIRGEFKQPQNGFKSFVTNRVEPELAKELSGAGVTYRREIENTFFRDLLSWVVPALIFVAVFLYFSRKFAEKGGMSGLMSVGKSGARLYAETGVKVSFGDVAGVEEAKAELYEVVQFLKSPQEFGRLGARMPKGILLVGPPGTGKTLLAKAVAGEAQVPFYSITGSEFVEMFVGVGAARVRDLFEQARKNAPCIIFIDELDALGKVRGVAGSFGGHDEKEQTLNQLLAELDGFDSRSGVVILAATNRPEVLDPALLRAGRFDRQVLVDRPDRTGREQILRVHLKKIKADEALNVEHLAHLTSGFTGADIANLINEAAMVATRRKAETVNEKDFVAAIERIVAGLEKKSRLLNEKEKAIVAHHEMGHAIMACLFPGVDKVQKISIIPRGLGALGYTMQRPTEDRYLMTRPELLDKICVLLGGRVAEELIFGEVSTGASDDLVRVTNIAEALVTRYGMSEVLGNIVFEQPTGNFLEVPGAGYRSRTYSEKSATEIDQEIRQIVAACALRTRESLAANLSILKKGAAQLLEKETLSEPEIELLMRDLVVKNAAPQRERDLSV

http://purl.uniprot.org/uniprot/Q6MJV1#attribution-D6D0D75B0781770BD3C4CC615AC12BF1
manual: true
evidence: ECO_0000255
source: MF_01458

Q6MRL7
type: Protein
reviewed: true
created: 2006-06-27
modified: 2023-09-13
version: 95
mnemonic: GATA_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP2D1DF79B0D224CCE
enzyme: http://purl.uniprot.org/enzyme/6.3.5.7
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP4100267B251ADCEE
annotation: SIPB81AD24AD4CE6A20
annotation: SIP85238FE89476231E
annotation: SIPCAE1967426CAA6A5
annotation: PRO_0000241075
annotation: SIPE3CCB291F6936EB6
annotation: SIPCB4C0EE1372A3D20
annotation: SIP08C855584CF2AADD
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0030956
classified with: GO_0005524
classified with: GO_0050567
classified with: GO_0006412
sequence: Q6MRL7-1
proteome: Chromosome

Q6MRL7-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0154
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.90.1300.10
type: Resource
database: Gene3D
comment: Amidase signature (AS) domain
signature sequence match: Gene3D 3.90.1300.10 match 1

MF_00120
type: Resource
database: HAMAP
comment: GatA
signature sequence match: HAMAP MF 00120 match 1

IPR000120
type: Resource
database: InterPro
comment: Amidase

IPR023631
type: Resource
database: InterPro
comment: Amidase_dom

IPR036928
type: Resource
database: InterPro
comment: AS_sf

IPR004412
type: Resource
database: InterPro
comment: GatA

TIGR00132
type: Resource
database: NCBIfam
comment: gatA
signature sequence match: NCBIfam TIGR00132 match 1

PTHR11895:SF151
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A
signature sequence match: PANTHER PTHR11895:SF151 match 1

PTHR11895
type: Resource
database: PANTHER
comment: TRANSAMIDASE
signature sequence match: PANTHER PTHR11895 match 1

PF01425
type: Resource
database: Pfam
comment: Amidase
signature sequence match: Pfam PF01425 match 1

SSF75304
type: Resource
database: SUPFAM
comment: Amidase signature (AS) enzymes
signature sequence match: SUPFAM SSF75304 match 1

SIP2D1DF79B0D224CCE
type: Structured Name
full name: Glutamyl-tRNA(Gln) amidotransferase subunit A
short name: Glu-ADT subunit A
ec name: 6.3.5.7

gatA
type: Gene
locus name: Bd0059

SIP4100267B251ADCEE
type: Function Annotation
comment: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

SIP85238FE89476231E
type: Subunit Annotation
comment: Heterotrimer of A, B and C subunits.

SIPCAE1967426CAA6A5
type: Similarity Annotation
comment: Belongs to the amidase family. GatA subfamily.

PRO_0000241075
type: Chain Annotation
comment: Glutamyl-tRNA(Gln) amidotransferase subunit A
mass: 52535
range: 22859178834671406tt1tt490

22859178834671406tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MRL7-1

22859178834671406tt490
type: Position
type: ExactPosition
position: 490
reference: Q6MRL7-1

SIPE3CCB291F6936EB6
type: Active Site Annotation
comment: Charge relay system
range: 22859178834671406tt78tt78

22859178834671406tt78
type: Position
type: ExactPosition
position: 78
reference: Q6MRL7-1

SIPCB4C0EE1372A3D20
type: Active Site Annotation
comment: Charge relay system
range: 22859178834671406tt153tt153

22859178834671406tt153
type: Position
type: ExactPosition
position: 153
reference: Q6MRL7-1

SIP08C855584CF2AADD
type: Active Site Annotation
comment: Acyl-ester intermediate
range: 22859178834671406tt177tt177

22859178834671406tt177
type: Position
type: ExactPosition
position: 177
reference: Q6MRL7-1

Q6MRL7-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 52535
value: MDLTFASLSEISEAVNNRSISAKEVTLHFLKRIENLNPKLNAFTSLNPQAVQEAEAVDARIANGEDVGLLAGVPFGIKEMFCTKGLTTTAGSKILENFVPPYDATAVARLKKSGIVVMGKLNQDEFAMGSSNETSFHGVVKNPWDLERVPGGSSGGSAAAQASRLVAGTLGTDTGGSIRQPASFCGIVGVKPTYGRVSRYGIVAYASSLDQAGPMVSSVRDAALTLEVISGFDPQDSTTTQKQVPAWSQNLKADVKGMKIGLMKEYMTGALDPDVQKTVENSVDTLKQLGAEIVEVSVPMTAFAVPVYYLVAASEASSNLSRYDGVKYGYRAEFKNLSAVDLEEFYSQTRGQAFGAEVKRRIMLGTYCLSSGYYDAFYNKAGQVRRLIMEQYLEAFKKCDVILSPVTTAPAFKIGERVSDPLAMYLNDIFTTSTNLAGLPGMSVPFGQSQSGLPIGIQLTAGHFEEQKMLNVAFALEGASLVKGKHPHVI

http://purl.uniprot.org/uniprot/Q6MRL7#attribution-211B70616AB828C89E92AFFD413454DC
manual: true
evidence: ECO_0000255
source: MF_00120

P61341
type: Protein
reviewed: true
created: 2004-05-10
modified: 2023-09-13
version: 93
mnemonic: GATB_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPC71EC75D25D6A970
enzyme: http://purl.uniprot.org/enzyme/6.3.5.-
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPB5D2A00E2486D3E5
annotation: SIPBE2D9CBC89E1301D
annotation: SIP92DE4938EA411298
annotation: SIPC9BF2935E09D37DF
annotation: SIP2A061888ABEA9AA4
annotation: PRO_0000148763
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/648
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0050566
classified with: GO_0005524
classified with: GO_0050567
classified with: GO_0006412
sequence: P61341-1
proteome: Chromosome

P61341-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0064
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/1.10.150.380
type: Resource
database: Gene3D
comment: GatB domain, N-terminal subdomain
signature sequence match: Gene3D 1.10.150.380 match 1

MF_00121
type: Resource
database: HAMAP
comment: GatB
signature sequence match: HAMAP MF 00121 match 1

IPR017959
type: Resource
database: InterPro
comment: Asn/Gln-tRNA_amidoTrfase_suB/E

IPR006075
type: Resource
database: InterPro
comment: Asn/Gln-tRNA_Trfase_suB/E_cat

IPR018027
type: Resource
database: InterPro
comment: Asn/Gln_amidotransferase

IPR003789
type: Resource
database: InterPro
comment: Asn/Gln_tRNA_amidoTrase-B-like

IPR004413
type: Resource
database: InterPro
comment: GatB

IPR042114
type: Resource
database: InterPro
comment: GatB_C_1

IPR023168
type: Resource
database: InterPro
comment: GatB_Yqey_C_2

IPR017958
type: Resource
database: InterPro
comment: Gln-tRNA_amidoTrfase_suB_CS

IPR014746
type: Resource
database: InterPro
comment: Gln_synth/guanido_kin_cat_dom

TIGR00133
type: Resource
database: NCBIfam
comment: gatB
signature sequence match: NCBIfam TIGR00133 match 1

PTHR11659
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED
signature sequence match: PANTHER PTHR11659 match 1

PTHR11659:SF0
type: Resource
database: PANTHER
comment: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL
signature sequence match: PANTHER PTHR11659:SF0 match 1

PF02934
type: Resource
database: Pfam
comment: GatB_N
signature sequence match: Pfam PF02934 match 1

PF02637
type: Resource
database: Pfam
comment: GatB_Yqey
signature sequence match: Pfam PF02637 match 1

SM00845
type: Resource
database: SMART
comment: GatB_Yqey
signature sequence match: SMART SM00845 match 1

SSF89095
type: Resource
database: SUPFAM
comment: GatB/YqeY motif
signature sequence match: SUPFAM SSF89095 match 1

SSF55931
type: Resource
database: SUPFAM
comment: Glutamine synthetase/guanido kinase
signature sequence match: SUPFAM SSF55931 match 1

PS01234
type: Resource
database: PROSITE
comment: GATB
signature sequence match: PROSITE PS01234 match 1

SIPC71EC75D25D6A970
type: Structured Name
full name: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
short name: Asp/Glu-ADT subunit B
ec name: 6.3.5.-

gatB
type: Gene
locus name: Bd0060

SIPB5D2A00E2486D3E5
type: Function Annotation
comment: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).

SIPC9BF2935E09D37DF
type: Subunit Annotation
comment: Heterotrimer of A, B and C subunits.

SIP2A061888ABEA9AA4
type: Similarity Annotation
comment: Belongs to the GatB/GatE family. GatB subfamily.

PRO_0000148763
type: Chain Annotation
comment: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
mass: 53589
range: 22577583077208366tt1tt477

22577583077208366tt1
type: Position
type: ExactPosition
position: 1
reference: P61341-1

22577583077208366tt477
type: Position
type: ExactPosition
position: 477
reference: P61341-1

P61341-1
type: Simple Sequence
modified: 2004-05-10
version: 1
mass: 53589
value: MSSRGYEAVIGIEIHVQLSTKTKIFSSESTAFEAGDNENTSPVSVGMPGTLPVLNSKVVEYSIKTGLALGCDIRRKSVFARKNYFYPDLPKGYQISQYDQPICENGSITFKVDGKEKTVSITRAHMEEDAGKSNHHGEYTLINYNRSGIPLLEVVSGPDMRTPQEAAEYARTIRQIVRYLDVCDGNLEEGSLRCDCNVSVRKEGAKQFGTKVEIKNINSFRFVEKAIEYEIERQIDCVERGDKIIQETRLWDPDKNRTFSMRAKEDAQDYRYFPDPDLQPVIVTDSMIEKYKKELPELPIARAQRFQDDHALPELDATVLTTEKDLADFYEDTAKESKNFKASSNWIMTELLRELNSANKNIKDSPIKPAQLGKMIAMIDKGTISGKIAKTIFQEMWASGNDPEVIMKEKGLVQISDPAAIEKLVDEVLAANAQTVEDHKSGKKKNLFGFFVGAVMKASKGQANPDLVNKILLEKLK

http://purl.uniprot.org/uniprot/P61341#attribution-566F024AB45254E6A93C8C84ADE6F906
manual: true
evidence: ECO_0000255
source: MF_00121

Q6MKE9
type: Protein
reviewed: true
created: 2005-02-01
modified: 2023-06-28
version: 85
mnemonic: GCH4_BDEBA
old mnemonic: Y2446_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPBF23C1F59B835ED8
enzyme: http://purl.uniprot.org/enzyme/3.5.4.16
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP81CE793077ACA4CD
annotation: SIP4E1A5E24D2F7B673
annotation: SIP84D75A5CF6EFDCE5
annotation: SIPFC25EBEBCEA49275
annotation: PRO_0000147702
annotation: SIP5D6AF3507230C549
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0003934
classified with: GO_0035998
sequence: Q6MKE9-1
proteome: Chromosome

Q6MKE9-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1469
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/3.10.270.10
type: Resource
database: Gene3D
comment: Urate Oxidase
signature sequence match: Gene3D 3.10.270.10 match 1

MF 01527 B
type: Resource
database: HAMAP
comment: GTP_cyclohydrol_B
signature sequence match: HAMAP MF 01527 B match 1

IPR022838
type: Resource
database: InterPro
comment: GTP_cyclohydrolase_FolE2

IPR003801
type: Resource
database: InterPro
comment: GTP_cyclohydrolase_FolE2/MptA

PTHR36445:SF1
type: Resource
database: PANTHER
comment: GTP CYCLOHYDROLASE FOLE2
signature sequence match: PANTHER PTHR36445:SF1 match 1

PTHR36445
type: Resource
database: PANTHER
comment: GTP CYCLOHYDROLASE MPTA
signature sequence match: PANTHER PTHR36445 match 1

PF02649
type: Resource
database: Pfam
comment: GCHY-1
signature sequence match: Pfam PF02649 match 1

SIPBF23C1F59B835ED8
type: Structured Name
full name: GTP cyclohydrolase FolE2
ec name: 3.5.4.16

folE2
type: Gene
locus name: Bd2446

SIP81CE793077ACA4CD
type: Function Annotation
comment: Converts GTP to 7,8-dihydroneopterin triphosphate.

SIPFC25EBEBCEA49275
type: Similarity Annotation
comment: Belongs to the GTP cyclohydrolase IV family.

PRO_0000147702
type: Chain Annotation
comment: GTP cyclohydrolase FolE2
mass: 33804
range: 22859178716772654tt1tt304

22859178716772654tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MKE9-1

22859178716772654tt304
type: Position
type: ExactPosition
position: 304
reference: Q6MKE9-1

SIP5D6AF3507230C549
type: Site Annotation
comment: May be catalytically important
range: 22859178716772654tt155tt155

22859178716772654tt155
type: Position
type: ExactPosition
position: 155
reference: Q6MKE9-1

Q6MKE9-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 33804
value: MTKQSLPDVAKETHSERFAPIDWVGMGAIELPVMLKQADGVYRIPARVDAKVSLDKKPSRGIHMSRLYLLSQELLTKSELSLGLLGTVTSEFLRTHEDLSTKALVQVQFEAPLVRKALKSNNQAWRSYPVITSAFNEEGQISYFVEVVVTYSSTCPASAALSRQLIQDGFKQNFSTDKPLDFDVVHSWLGTPQGIVATPHAQRSFARVKAEVGANYNYGDLIDIVEEALQTAVQGAVKREDEQEFALRNGQNLMFCEDAARRVKEALDAKADVLDYVAEFSHVESLHPHNAVSHISKGLKLRSF

http://purl.uniprot.org/uniprot/Q6MKE9#attribution-80C26FB8A9676D752FC7A8FACE9541FF
manual: true
evidence: ECO_0000255
source: MF_01527

Q6MKW4
type: Protein
reviewed: true
created: 2005-04-26
modified: 2023-09-13
version: 90
mnemonic: GCS2_BDEBA
old mnemonic: CAAL_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP0A6D28635788698A
alternative name: SIPD2699C3EDD31A8EF
enzyme: http://purl.uniprot.org/enzyme/6.3.2.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP8662B2C50FFB286A
annotation: SIP98206DBE5A910646
annotation: SIPDA30D43DD2000559
annotation: PRO_0000218184
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005524
classified with: GO_0004357
classified with: GO_0042398
sequence: Q6MKW4-1
proteome: Chromosome

Q6MKW4-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG2170
type: Resource
database: eggNOG
comment: Bacteria

MF_01609
type: Resource
database: HAMAP
comment: Glu_cys_ligase_2
signature sequence match: HAMAP MF 01609 match 1

IPR006336
type: Resource
database: InterPro
comment: GCS2

IPR011793
type: Resource
database: InterPro
comment: YbdK

TIGR02050
type: Resource
database: NCBIfam
comment: gshA_cyan_rel
signature sequence match: NCBIfam TIGR02050 match 1

PTHR36510
type: Resource
database: PANTHER
comment: GLUTAMATE--CYSTEINE LIGASE 2-RELATED
signature sequence match: PANTHER PTHR36510 match 1

PTHR36510:SF1
type: Resource
database: PANTHER
comment: GLUTAMATE--CYSTEINE LIGASE 2-RELATED
signature sequence match: PANTHER PTHR36510:SF1 match 1

PF04107
type: Resource
database: Pfam
comment: GCS2
signature sequence match: Pfam PF04107 match 1

SIP0A6D28635788698A
type: Structured Name
full name: Putative glutamate--cysteine ligase 2
ec name: 6.3.2.2

SIPD2699C3EDD31A8EF
type: Structured Name
full name: Gamma-glutamylcysteine synthetase 2
short name: GCS 2
short name: Gamma-GCS 2

http://purl.uniprot.org/uniprot/Q6MKW4#gene-MD56499B67F500F6533517E90EB3C5807F9
type: Gene
locus name: Bd2263

SIP8662B2C50FFB286A
type: Function Annotation
comment: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.

SIPDA30D43DD2000559
type: Similarity Annotation
comment: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

PRO_0000218184
type: Chain Annotation
comment: Putative glutamate--cysteine ligase 2
mass: 43760
range: 22859178717951022tt1tt378

22859178717951022tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MKW4-1

22859178717951022tt378
type: Position
type: ExactPosition
position: 378
reference: Q6MKW4-1

Q6MKW4-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 43760
value: MTKPQPIPFGKSDLFSLGVEVELQIIHPETRNLFPISPDILEEWSLQSPHLKPEVFQSMLEIDTPICKNVQEVEYELLLTSRELLRICKKHGARLASNGTHPFAKWHHRIFYPSDRYEYLLERNQHIARRLMIYGLHVHLGMKDGDHCIAMMNEFLYYLPHMLAMSASSPFWTGHDTGLASSRITVFEAHPAGGTPCRVENWAQFEDIVQKLTRSNSIGSFKDIWWDIRPSPNYGTLEIRICDGVPGIRKTTRLVAFIHLLAKHLQKRLEQGIRRQTPDDWMVRENKWRASRHGLDCEVLIDNDGMTKNLREDIKDLLAAMKEDAAEMGYTEYLKQLVEEDLTHPSYEIQRALFEKTGSLEHVVDSLCDVFEKDLDVV

http://purl.uniprot.org/uniprot/Q6MKW4#attribution-1C5BE1304D996528858A134AE9EE2E6D
manual: true
evidence: ECO_0000255
source: MF_01609

Q6MPZ6
type: Protein
reviewed: true
created: 2006-03-07
modified: 2023-09-13
version: 105
mnemonic: GCSP_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP54E12C0EC169311E
alternative name: SIPAFA551B9491A4FFB
alternative name: SIPF50B13214A6A61FA
alternative name: SIP6CB0734C231ACED3
enzyme: http://purl.uniprot.org/enzyme/1.4.4.2
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPA2D8BAFE5CA97302
annotation: SIP30B48090EB3EC725
annotation: SIP279A084B3FD3205E
annotation: SIP0D1C65B313E0C783
annotation: SIP5E3F6F52332A0D72
annotation: PRO_0000227095
annotation: SIP235E535E8AA86345
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/560
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004375
classified with: GO_0019464
sequence: Q6MPZ6-1
proteome: Chromosome

Q6MPZ6-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0403
type: Resource
database: eggNOG
comment: Bacteria

COG1003
type: Resource
database: eggNOG
comment: Bacteria

cd00613
type: Resource
database: CDD
comment: GDC-P
signature sequence match: CDD cd00613 match 1
signature sequence match: CDD cd00613 match 2

http://purl.uniprot.org/gene3d/3.90.1150.10
type: Resource
database: Gene3D
comment: Aspartate Aminotransferase, domain 1
signature sequence match: Gene3D 3.90.1150.10 match 1
signature sequence match: Gene3D 3.90.1150.10 match 2

http://purl.uniprot.org/gene3d/3.40.640.10
type: Resource
database: Gene3D
comment: Type I PLP-dependent aspartate aminotransferase-like (Major domain)
signature sequence match: Gene3D 3.40.640.10 match 1
signature sequence match: Gene3D 3.40.640.10 match 2

MF_00711
type: Resource
database: HAMAP
comment: GcvP
signature sequence match: HAMAP MF 00711 match 1

IPR003437
type: Resource
database: InterPro
comment: GcvP

IPR020581
type: Resource
database: InterPro
comment: GDC_P

IPR015424
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase

IPR015421
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_major

IPR015422
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_small

TIGR00461
type: Resource
database: NCBIfam
comment: gcvP
signature sequence match: NCBIfam TIGR00461 match 1

PTHR11773:SF1
type: Resource
database: PANTHER
comment: GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL
signature sequence match: PANTHER PTHR11773:SF1 match 1

PTHR11773
type: Resource
database: PANTHER
comment: GLYCINE DEHYDROGENASE, DECARBOXYLATING
signature sequence match: PANTHER PTHR11773 match 1

PF02347
type: Resource
database: Pfam
comment: GDC-P
signature sequence match: Pfam PF02347 match 1
signature sequence match: Pfam PF02347 match 2

SSF53383
type: Resource
database: SUPFAM
comment: PLP-dependent transferases
signature sequence match: SUPFAM SSF53383 match 1
signature sequence match: SUPFAM SSF53383 match 2

SIP54E12C0EC169311E
type: Structured Name
full name: Glycine dehydrogenase (decarboxylating)
ec name: 1.4.4.2

SIPAFA551B9491A4FFB
type: Structured Name
full name: Glycine cleavage system P-protein

SIPF50B13214A6A61FA
type: Structured Name
full name: Glycine decarboxylase

SIP6CB0734C231ACED3
type: Structured Name
full name: Glycine dehydrogenase (aminomethyl-transferring)

gcvP
type: Gene
locus name: Bd0692

SIPA2D8BAFE5CA97302
type: Function Annotation
comment: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

SIP0D1C65B313E0C783
type: Subunit Annotation
comment: The glycine cleavage system is composed of four proteins: P, T, L and H.

SIP5E3F6F52332A0D72
type: Similarity Annotation
comment: Belongs to the GcvP family.

PRO_0000227095
type: Chain Annotation
comment: Glycine dehydrogenase (decarboxylating)
mass: 104226
range: 22859178802034222tt1tt958

22859178802034222tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MPZ6-1

22859178802034222tt958
type: Position
type: ExactPosition
position: 958
reference: Q6MPZ6-1

SIP235E535E8AA86345
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 22859178802034222tt705tt705

22859178802034222tt705
type: Position
type: ExactPosition
position: 705
reference: Q6MPZ6-1

Q6MPZ6-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 104226
value: MKIADLSPTNEFIPRHIGPTDSDIHEMLKTLGFNSLDQMADKVIPAQIRTTHAYADVGNGISEHGLLNHLKQMVSKNKVYKNYIGMGYHDTITPTVIQRNIFENPVWYTAYTPYQPEISQGRLEALLNFQTMIADLNGMEIANASLLDEGTAAAEAMFMAHSLCKNKANAFVVSPDMHPHVIEVIGTRAEPLGFEMIVMDPAKYDFAKPVFGVFFQYPNTNGTVEDYAAIAKKYKDHGALVTASTDLLAMTLLTPPGEWGADMVVGNSQRFGVPLGFGGPHAGFLATKDAFKRLMPGRLVGVSVDSQGKSALRLALQTREQHIRREKATSNICTAQVLLANMASMYAVYHGPAGLKKIALRVQRLTAILSAGLKKLNLEVGAGHVFDTVTVKTDKAAEIIAQAEKMQMNFRNYGGGKLGVSLNEATTLEDVEQIWAAFNLGKAAGFTALSVDESLADVTLPANLTRSTAYMTHQVFNSHHSETEMLRYIHHLQNKDLTLTHSMIPLGSCTMKLNATTELVPVSWPEISKLHPFAPTAQAVGLIEMIHDLEKKLCDITGFAAVSLQPNAGSQGEYAGLLVIRKYHQSRGQGHRNICLIPSSAHGTNPASAALVNMQVVVVACDDQGNVDVADLKAKAEQHKDNLAALMITYPSTHGVFEEGIVEICKIIHDNGGQVYMDGANMNALVGMCRPGVFGPDVSHMNLHKTFSIPHGGGGPGVGPIGVGAHLAEFLPKHSLVPEAGPANGISATTSAPWGSASILPISWAYITMMGAQGLRKATLVSILSANYIAKKLEAHYPVLYKGKNGLVAHECIVDVREIKKTSGIDVTDVAKRLMDFGFHAPTMSFPVAGTLMIEPTESESKKELDRFIESMVTIRKEIAAVETGKMDKENNALKNAPHTAQMLMKPEWNHPYSREEAVYPVEWLRGNKFWPVVGRVDNAYGDRNLICSCPSIEDYQA

http://purl.uniprot.org/uniprot/Q6MPZ6#attribution-2893DE7D799CD88F46B1BBBB8E84E401
manual: true
evidence: ECO_0000255
source: MF_00711

Q6MQ03
type: Protein
reviewed: true
created: 2005-02-15
modified: 2023-09-13
version: 97
mnemonic: GCST_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIPC2264701DB8A87E7
alternative name: SIPEC22F3B18B1707E5
enzyme: http://purl.uniprot.org/enzyme/2.1.2.10
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIP91FD58FBB3EB9CA9
annotation: SIP03F69737CC103849
annotation: SIPBB110BF868EB8DF2
annotation: SIP120B00FE486915E3
annotation: PRO_0000122545
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/32
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0004047
classified with: GO_0008483
classified with: GO_0019464
sequence: Q6MQ03-1
proteome: Chromosome

Q6MQ03-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG0404
type: Resource
database: eggNOG
comment: Bacteria

http://purl.uniprot.org/gene3d/2.40.30.110
type: Resource
database: Gene3D
comment: Aminomethyltransferase beta-barrel domains
signature sequence match: Gene3D 2.40.30.110 match 1

http://purl.uniprot.org/gene3d/3.30.70.1400
type: Resource
database: Gene3D
comment: Aminomethyltransferase beta-barrel domains
signature sequence match: Gene3D 3.30.70.1400 match 1

http://purl.uniprot.org/gene3d/4.10.1250.10
type: Resource
database: Gene3D
comment: Aminomethyltransferase fragment
signature sequence match: Gene3D 4.10.1250.10 match 1

MF_00259
type: Resource
database: HAMAP
comment: GcvT
signature sequence match: HAMAP MF 00259 match 1

IPR006223
type: Resource
database: InterPro
comment: GCS_T

IPR022903
type: Resource
database: InterPro
comment: GCS_T_bac

IPR028896
type: Resource
database: InterPro
comment: GCST/YgfZ/DmdA

IPR013977
type: Resource
database: InterPro
comment: GCV_T_C

IPR006222
type: Resource
database: InterPro
comment: GCV_T_N

IPR029043
type: Resource
database: InterPro
comment: GcvT/YgfZ_C

IPR027266
type: Resource
database: InterPro
comment: TrmE/GcvT_dom1

TIGR00528
type: Resource
database: NCBIfam
comment: gcvT
signature sequence match: NCBIfam TIGR00528 match 1

PTHR43757
type: Resource
database: PANTHER
comment: AMINOMETHYLTRANSFERASE
signature sequence match: PANTHER PTHR43757 match 1

PTHR43757:SF2
type: Resource
database: PANTHER
comment: AMINOMETHYLTRANSFERASE, MITOCHONDRIAL
signature sequence match: PANTHER PTHR43757:SF2 match 1

PF01571
type: Resource
database: Pfam
comment: GCV_T
signature sequence match: Pfam PF01571 match 1

PF08669
type: Resource
database: Pfam
comment: GCV_T_C
signature sequence match: Pfam PF08669 match 1

PIRSF006487
type: Resource
database: PIRSF
comment: GcvT
signature sequence match: PIRSF PIRSF006487 match 1

SSF101790
type: Resource
database: SUPFAM
comment: Aminomethyltransferase beta-barrel domain
signature sequence match: SUPFAM SSF101790 match 1

SSF103025
type: Resource
database: SUPFAM
comment: Folate-binding domain
signature sequence match: SUPFAM SSF103025 match 1

SIPC2264701DB8A87E7
type: Structured Name
full name: Aminomethyltransferase
ec name: 2.1.2.10

SIPEC22F3B18B1707E5
type: Structured Name
full name: Glycine cleavage system T protein

gcvT
type: Gene
locus name: Bd0684

SIP91FD58FBB3EB9CA9
type: Function Annotation
comment: The glycine cleavage system catalyzes the degradation of glycine.

SIPBB110BF868EB8DF2
type: Subunit Annotation
comment: The glycine cleavage system is composed of four proteins: P, T, L and H.

SIP120B00FE486915E3
type: Similarity Annotation
comment: Belongs to the GcvT family.

PRO_0000122545
type: Chain Annotation
comment: Aminomethyltransferase
mass: 39861
range: 22859178816058158tt1tt360

22859178816058158tt1
type: Position
type: ExactPosition
position: 1
reference: Q6MQ03-1

22859178816058158tt360
type: Position
type: ExactPosition
position: 360
reference: Q6MQ03-1

Q6MQ03-1
type: Simple Sequence
modified: 2004-07-05
version: 1
mass: 39861
value: MKKTPLADTHEKLGARMVDFAGWYMPVQYIGLREEHNNVRTNVGLFDVSHMGEVRVKGPKALETLEWLTTNDVSKLNDGEAQYSLLPNDQGGLVDDIIVYCLSKDSDYLVCVNASNKDKDFAWMTKHNKGADITDESDLWGQIAIQGPKALELCDRVFDIKVSEMKSFTVKSGTFKGHKIMIATTGYTGEKGCEVFVEAAGTADLWMTLLEKGKDLGCMGIGLGARDTLRTEMKYSLYGHEIDDTTNPYEAGLGWVIKPAKKDFMNKAQIVGKKEAGLTRNLVGFKMLEKGIPRQGYSLFSFDNKEIGKVTSGTHSPTLDEPIGIAFIDVAYAKEGTEFLLDIRGRKVKAVVCKTPFVTK

http://purl.uniprot.org/uniprot/Q6MQ03#attribution-D693840B1AF9F2C1A1B8905C2208AEAB
manual: true
evidence: ECO_0000255
source: MF_00259

Q6MLS4
type: Protein
reviewed: true
created: 2005-12-20
modified: 2023-09-13
version: 98
mnemonic: GLMM_BDEBA
citation: http://purl.uniprot.org/citations/14752164
recommended name: SIP4599C31D49F2F569
enzyme: http://purl.uniprot.org/enzyme/5.4.2.10
organism: http://purl.uniprot.org/taxonomy/264462
annotation: SIPA49425077BB3E782
annotation: SIPF1BB0AEAB9506E43
annotation: SIP2D585FCD3A0CF534
annotation: SIPA5B3584936115460
annotation: SIPA6E85661E89A3A6E
annotation: PRO_0000147850
annotation: SIPA19E470E6BF14154
annotation: SIP9ACCB4E3A95775D4
annotation: SIPECA694E6E78A4C32
annotation: SIP12FFD970571484A9
annotation: SIP8B540D95158EFB30
annotation: SIP3557DFFDC6AB959E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0000287
classified with: GO_0008966
classified with: GO_0005975
sequence: Q6MLS4-1
proteome: Chromosome

Q6MLS4-citation-14752164
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
type: Strain

COG1109
type: Resource
database: eggNOG
comment: Bacteria

cd05802
type: Resource
database: CDD
comment: GlmM
signature sequence match: CDD cd05802 match 1

http://purl.uniprot.org/gene3d/3.40.120.10
type: Resource
database: Gene3D
comment: Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3
signature sequence match: Gene3D 3.40.120.10 match 1
signature sequence match: Gene3D 3.40.120.10 match 2
signature sequence match: Gene3D 3.40.120.10 match 3

http://purl.uniprot.org/gene3d/3.30.310.50
type: Resource
database: Gene3D
comment: Alpha-D-phosphohexomutase, C-terminal domain
signature sequence match: Gene3D 3.30.310.50 match 1

MF 01554 B
type: Resource
database: HAMAP
comment: GlmM_B
signature sequence match: HAMAP MF 01554 B match 1

IPR005844
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-I

IPR016055
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-I/II/III

IPR005845
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-II

IPR005846
type: Resource
database: InterPro
comment: A-D-PHexomutase_a/b/a-III

IPR005843
type: Resource
database: InterPro
comment: A-D-PHexomutase_C

IPR036900
type: Resource
database: InterPro
comment: A-D-PHexomutase_C_sf

IPR016066
type: Resource
database: InterPro
comment: A-D-PHexomutase_CS

IPR005841
type: Resource
database: InterPro
comment: Alpha-D-phosphohexomutase_SF

IPR006352
type: Resource
database: InterPro
comment: GlmM_bact

TIGR01455
type: Resource
database: NCBIfam
comment: glmM
signature sequence match: NCBIfam TIGR01455 match 1

PTHR42946:SF1
type: Resource
database: PANTHER
comment: PHOSPHOGLUCOSAMINE MUTASE FAMILY PROTEIN
signature sequence match: PANTHER PTHR42946:SF1 match 1

PTHR42946
type: Resource
database: PANTHER
comment: PHOSPHOHEXOSE MUTASE
signature sequence match: PANTHER PTHR42946 match 1

PF02878
type: Resource
database: Pfam
comment: PGM_PMM_I
signature sequence match: Pfam PF02878 match 1

PF02879
type: Resource
database: Pfam
comment: PGM_PMM_II
signature sequence match: Pfam PF02879 match 1

PF02880
type: Resource
database: Pfam
comment: PGM_PMM_III
signature sequence match: Pfam PF02880 match 1

PF00408
type: Resource
database: Pfam
comment: PGM_PMM_IV
signature sequence match: Pfam PF00408 match 1

PR00509
type: Resource
database: PRINTS
comment: PGMPMM

SSF55957
type: Resource
database: SUPFAM
comment: Phosphoglucomutase, C-terminal domain
signature sequence match: SUPFAM SSF55957 match 1

SSF53738
type: Resource
database: SUPFAM
comment: Phosphoglucomutase, first 3 domains
signature sequence match: SUPFAM SSF53738 match 1
signature sequence match: SUPFAM SSF53738 match 2
signature sequence match: SUPFAM SSF53738 match 3

PS00710
type: Resource
database: PROSITE
comment: PGM_PMM
signature sequence match: PROSITE PS00710 match 1

SIP4599C31D49F2F569
type: Structured Name
full name: Phosphoglucosamine mutase
ec name: 5.4.2.10

glmM
type: Gene
locus name: Bd1931

SIPA49425077BB3E782
type: Function Annotation
comment: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

SIP2D585FCD3A0CF534
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIPA5B3584936115460
type: PTM Annotation
comment: Activated by phosphorylation.