A9UZ24
type: Protein
reviewed: true
created: 2008-06-10
modified: 2023-09-13
version: 69
mnemonic: BCAT_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP62A076A3A68FB7CB
enzyme: http://purl.uniprot.org/enzyme/2.6.1.42
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPB2F1D525DED9006F
annotation: SIP803D6BB793C366AD
annotation: SIPEDA97C3350FDA1D1
annotation: SIP9C5AB812C26957C9
annotation: SIP320A918BD712CCD5
annotation: SIPE0FE602FBEA80197
annotation: SIP6FF1D2D80ACE1BC8
annotation: PRO_0000340237
annotation: SIPCE036AA51EB86561
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/32
classified with: http://purl.uniprot.org/keywords/100
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005739
classified with: GO_0004084
classified with: GO_0052656
classified with: GO_0052654
classified with: GO_0050048
classified with: GO_0052655
classified with: GO_0009098
classified with: GO_0009099
sequence: A9UZ24-1
proteome: Unassembled WGS sequence

A9UZ24-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0975
type: Resource
database: eggNOG
comment: Eukaryota

cd01557
type: Resource
database: CDD
comment: BCAT_beta_family
signature sequence match: CDD cd01557 match 1

http://purl.uniprot.org/gene3d/3.20.10.10
type: Resource
database: Gene3D
comment: D-amino Acid Aminotransferase, subunit A, domain 2
signature sequence match: Gene3D 3.20.10.10 match 1

IPR001544
type: Resource
database: InterPro
comment: Aminotrans_IV

IPR018300
type: Resource
database: InterPro
comment: Aminotrans_IV_CS

IPR036038
type: Resource
database: InterPro
comment: Aminotransferase-like

IPR005786
type: Resource
database: InterPro
comment: B_amino_transII

IPR043132
type: Resource
database: InterPro
comment: BCAT-like_C

IPR043131
type: Resource
database: InterPro
comment: BCAT-like_N

IPR033939
type: Resource
database: InterPro
comment: BCAT_family

TIGR01123
type: Resource
database: NCBIfam
comment: ilvE_II
signature sequence match: NCBIfam TIGR01123 match 1

PTHR11825:SF44
type: Resource
database: PANTHER
comment: BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE
signature sequence match: PANTHER PTHR11825:SF44 match 1

PTHR11825
type: Resource
database: PANTHER
comment: SUBGROUP IIII AMINOTRANSFERASE
signature sequence match: PANTHER PTHR11825 match 1

PF01063
type: Resource
database: Pfam
comment: Aminotran_4
signature sequence match: Pfam PF01063 match 1

PIRSF006468
type: Resource
database: PIRSF
comment: BCAT1
signature sequence match: PIRSF PIRSF006468 match 1

SSF56752
type: Resource
database: SUPFAM
comment: D-aminoacid aminotransferase-like PLP-dependent enzymes
signature sequence match: SUPFAM SSF56752 match 1

PS00770
type: Resource
database: PROSITE
comment: AA_TRANSFER_CLASS_4
signature sequence match: PROSITE PS00770 match 1

SIP62A076A3A68FB7CB
type: Structured Name
full name: Branched-chain-amino-acid aminotransferase
ec name: 2.6.1.42

http://purl.uniprot.org/uniprot/A9UZ24#gene-MD591EC2D48594221DEB1A18CED4664BF99
type: Gene
orf name: 37018

SIPB2F1D525DED9006F
type: Function Annotation
comment: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.

SIPE0FE602FBEA80197
type: Subunit Annotation
comment: Homodimer.

SIP6FF1D2D80ACE1BC8
type: Similarity Annotation
comment: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

PRO_0000340237
type: Chain Annotation
comment: Branched-chain-amino-acid aminotransferase
mass: 43290
range: 18358912234435630tt1tt390

18358912234435630tt1
type: Position
type: ExactPosition
position: 1
reference: A9UZ24-1

18358912234435630tt390
type: Position
type: ExactPosition
position: 390
reference: A9UZ24-1

SIPCE036AA51EB86561
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18358912234435630tt225tt225

18358912234435630tt225
type: Position
type: ExactPosition
position: 225
reference: A9UZ24-1

A9UZ24-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 43290
value: MAAALRLTPHMRQAYPVVAAPSVARLSTLDASKLTIETTTQPRERVEKTKLVFGHTFSDHMLKCKWDVNEGWAAPTISPYANLSLAPSSIVLHYAIECFEGMKAFRGDDDRIRLFRPNLNMDRLHRSSVRLALPDFDQDELLKCITELVIKDKDWIPAGRGYSLYLRPTHIGTAEYLGVGKSSSSLLFCINSPSGAYYSTGFKPVSLLADPAYVRAWPGGVGNTKGGCNYAPSIYPQSQAQAQGCQQVLWLFGEDHEVTEVGTMNLFMYWKNEQGEDELITPPLDGTILPGVTRQSIVDMARGWNEFKVSERKFNMGQVSRALKEGRVYEMFGAGTAATVCPIGQIKYLGEDLNVPLALGNSGELTNRIWTDIFDIQYGAVEHEWAPVIA

http://purl.uniprot.org/uniprot/A9UZ24#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UZ24#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UZ24#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UZS7
type: Protein
reviewed: true
created: 2009-05-05
modified: 2023-02-22
version: 66
mnemonic: BOP1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP29541BBB9FADD78D
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPCB5F77532BEAE9E4
annotation: SIP609FE57FA3456F5D
annotation: SIPBDCD2C2BF3312C8C
annotation: PRO_0000370409
annotation: SIP986AD5B5EC856A12
annotation: SIP41540EA6B46D2111
annotation: SIPB5F13D871EFF934C
annotation: SIPB6BCF8CDED9C9450
annotation: SIP32FB2667BBECC624
annotation: SIPAF6913701D28EF2F
annotation: SIP6F785E554CFCF272
annotation: SIP1FA2CCBFE95DE81D
annotation: SIP1DF3E7BAE7B50444
annotation: SIPD0637D4A06F9200D
annotation: SIPCE30D3557B1BA9C5
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/690
classified with: http://purl.uniprot.org/keywords/698
classified with: http://purl.uniprot.org/keywords/853
classified with: GO_0005654
classified with: GO_0070545
classified with: GO_0030687
classified with: GO_0043021
classified with: GO_0000466
classified with: GO_0000463
sequence: A9UZS7-1
proteome: Unassembled WGS sequence

A9UZS7-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0650
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/2.130.10.10
type: Resource
database: Gene3D
comment: YVTN repeat-like/Quinoprotein amine dehydrogenase
signature sequence match: Gene3D 2.130.10.10 match 1

MF_03027
type: Resource
database: HAMAP
comment: BOP1
signature sequence match: HAMAP MF 03027 match 1

IPR028598
type: Resource
database: InterPro
comment: BOP1/Erb1

IPR012953
type: Resource
database: InterPro
comment: BOP1_N_dom

IPR015943
type: Resource
database: InterPro
comment: WD40/YVTN_repeat-like_dom_sf

IPR001680
type: Resource
database: InterPro
comment: WD40_repeat

IPR019775
type: Resource
database: InterPro
comment: WD40_repeat_CS

IPR036322
type: Resource
database: InterPro
comment: WD40_repeat_dom_sf

PTHR17605:SF0
type: Resource
database: PANTHER
comment: RIBOSOME BIOGENESIS PROTEIN BOP1
signature sequence match: PANTHER PTHR17605:SF0 match 1

PTHR17605
type: Resource
database: PANTHER
comment: RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN
signature sequence match: PANTHER PTHR17605 match 1

PF08145
type: Resource
database: Pfam
comment: BOP1NT
signature sequence match: Pfam PF08145 match 1

PF00400
type: Resource
database: Pfam
comment: WD40
signature sequence match: Pfam PF00400 match 1
signature sequence match: Pfam PF00400 match 2
signature sequence match: Pfam PF00400 match 3
signature sequence match: Pfam PF00400 match 4
signature sequence match: Pfam PF00400 match 5
signature sequence match: Pfam PF00400 match 6

SM01035
type: Resource
database: SMART
comment: BOP1NT
signature sequence match: SMART SM01035 match 1

SM00320
type: Resource
database: SMART
comment: WD40
signature sequence match: SMART SM00320 match 1
signature sequence match: SMART SM00320 match 2
signature sequence match: SMART SM00320 match 3
signature sequence match: SMART SM00320 match 4
signature sequence match: SMART SM00320 match 5
signature sequence match: SMART SM00320 match 6
signature sequence match: SMART SM00320 match 7

SSF50978
type: Resource
database: SUPFAM
comment: WD40 repeat-like
signature sequence match: SUPFAM SSF50978 match 1

PS00678
type: Resource
database: PROSITE
comment: WD_REPEATS_1
signature sequence match: PROSITE PS00678 match 1
signature sequence match: PROSITE PS00678 match 2
signature sequence match: PROSITE PS00678 match 3
signature sequence match: PROSITE PS00678 match 4
signature sequence match: PROSITE PS00678 match 5

PS50082
type: Resource
database: PROSITE
comment: WD_REPEATS_2
signature sequence match: PROSITE PS50082 match 1
signature sequence match: PROSITE PS50082 match 2
signature sequence match: PROSITE PS50082 match 3
signature sequence match: PROSITE PS50082 match 4
signature sequence match: PROSITE PS50082 match 5
signature sequence match: PROSITE PS50082 match 6

PS50294
type: Resource
database: PROSITE
comment: WD_REPEATS_REGION
signature sequence match: PROSITE PS50294 match 1
signature sequence match: PROSITE PS50294 match 2

SIP29541BBB9FADD78D
type: Structured Name
full name: Ribosome biogenesis protein BOP1 homolog

http://purl.uniprot.org/uniprot/A9UZS7#gene-MD5C6242C432DD566AEB517A9AABA26C490
type: Gene
orf name: 37129

SIPCB5F77532BEAE9E4
type: Function Annotation
comment: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

SIPBDCD2C2BF3312C8C
type: Similarity Annotation
comment: Belongs to the WD repeat BOP1/ERB1 family.

PRO_0000370409
type: Chain Annotation
comment: Ribosome biogenesis protein BOP1 homolog
mass: 90954
range: 18358912236599086tt1tt799

18358912236599086tt1
type: Position
type: ExactPosition
position: 1
reference: A9UZS7-1

18358912236599086tt799
type: Position
type: ExactPosition
position: 799
reference: A9UZS7-1

SIP986AD5B5EC856A12
type: Repeat Annotation
comment: WD 1
range: 18358912236599086tt457tt498

18358912236599086tt457
type: Position
type: ExactPosition
position: 457
reference: A9UZS7-1

18358912236599086tt498
type: Position
type: ExactPosition
position: 498
reference: A9UZS7-1

SIP41540EA6B46D2111
type: Repeat Annotation
comment: WD 2
range: 18358912236599086tt500tt538

18358912236599086tt500
type: Position
type: ExactPosition
position: 500
reference: A9UZS7-1

18358912236599086tt538
type: Position
type: ExactPosition
position: 538
reference: A9UZS7-1

SIPB5F13D871EFF934C
type: Repeat Annotation
comment: WD 3
range: 18358912236599086tt584tt626

18358912236599086tt584
type: Position
type: ExactPosition
position: 584
reference: A9UZS7-1

18358912236599086tt626
type: Position
type: ExactPosition
position: 626
reference: A9UZS7-1

SIPB6BCF8CDED9C9450
type: Repeat Annotation
comment: WD 4
range: 18358912236599086tt629tt669

18358912236599086tt629
type: Position
type: ExactPosition
position: 629
reference: A9UZS7-1

18358912236599086tt669
type: Position
type: ExactPosition
position: 669
reference: A9UZS7-1

SIP32FB2667BBECC624
type: Repeat Annotation
comment: WD 5
range: 18358912236599086tt670tt709

18358912236599086tt670
type: Position
type: ExactPosition
position: 670
reference: A9UZS7-1

18358912236599086tt709
type: Position
type: ExactPosition
position: 709
reference: A9UZS7-1

SIPAF6913701D28EF2F
type: Repeat Annotation
comment: WD 6
range: 18358912236599086tt713tt752

18358912236599086tt713
type: Position
type: ExactPosition
position: 713
reference: A9UZS7-1

18358912236599086tt752
type: Position
type: ExactPosition
position: 752
reference: A9UZS7-1

SIP6F785E554CFCF272
type: Repeat Annotation
comment: WD 7
range: 18358912236599086tt769tt799

18358912236599086tt769
type: Position
type: ExactPosition
position: 769
reference: A9UZS7-1

SIP1FA2CCBFE95DE81D
type: Region Annotation
comment: Disordered
range: 18358912236599086tt1tt171

18358912236599086tt171
type: Position
type: ExactPosition
position: 171
reference: A9UZS7-1

SIP1DF3E7BAE7B50444
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912236599086tt9tt41

18358912236599086tt9
type: Position
type: ExactPosition
position: 9
reference: A9UZS7-1

18358912236599086tt41
type: Position
type: ExactPosition
position: 41
reference: A9UZS7-1

SIPD0637D4A06F9200D
type: Compositional Bias Annotation
comment: Acidic residues
range: 18358912236599086tt94tt124

18358912236599086tt94
type: Position
type: ExactPosition
position: 94
reference: A9UZS7-1

18358912236599086tt124
type: Position
type: ExactPosition
position: 124
reference: A9UZS7-1

SIPCE30D3557B1BA9C5
type: Compositional Bias Annotation
comment: Polar residues
range: 18358912236599086tt125tt160

18358912236599086tt125
type: Position
type: ExactPosition
position: 125
reference: A9UZS7-1

18358912236599086tt160
type: Position
type: ExactPosition
position: 160
reference: A9UZS7-1

A9UZS7-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 90954
value: MPRRVRAQKRTAGVVEDEEVKAEQVRREHKAKQKQAVGSDAEQEEEELFPDSLHGPDSESDVTDDEQIDEEARQADRDLLKELVTLQGLNGEDPSDADNDDDDDEEEAASDDDDEEEDAEPSSDSSNEASDAGQEEGTTDPHTTTDDKASATTQMVVYSSDDDTSDEEHSLNRVGRIPMEWYEDYEHIGYDLNGKRIRKPKQKDRLEKFLDAFEAGNNGRTIYDPVTGKEIELTDDDINMIKRIQSGQLPDTGINPYEDYVDFFTHEKMQTPVVDKPEPKRRFVPSKWEHKKIMKIVRSIRKGLIKLPTSDDEKDKSSEEEQYYDVWGNEDDPNDPRIKVRQANHIAAPKVALPHHAESYNPPEEYLPTDAEAEKWRNAHEDDRERNYLPHKYGSLRLVPAYDQYIQERFHRCLDLYLCPRARRIRMNVDPEDLLPKLPKPEDLQPFPSAPSLVYRGHKARVTSISCDPTGQWLVSGSDDKTIRVWEISTGRCVRVVTVDAEVNMVAWCPNAGVSIVAVAHGHTVSLICPRVATAAIDKATAVLCNQSIEKPSQGAEEGMRATPTWNRIRGERQDQDGIFFEIPHHAEVMQVTWHHKGNYFASVMPRAETQSVCVHSLNRQSTQHPFQKRNRDVQRVLFHPTQPLFFVATKTHVRVYNLQAQALVKKLLTGVRWLSSLAIHPAGDNLIIGSYDKRLCWFDMDLSIKPYKILRYHKYALRQVCFHKKYPIFASCGDDGNVHVLHGMVYNDLGQNPLIVPVKIIKAHNQTSDGMGVMDCTFHPSQPWLFSAGSDGSIKLHV

http://purl.uniprot.org/uniprot/A9UZS7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UZS7#attribution-8F2859D8305D15330898A6B8F18233F0
manual: true
evidence: ECO_0000255
source: MF_03027

A9UNU6
type: Protein
reviewed: true
created: 2008-04-08
modified: 2023-05-03
version: 49
mnemonic: BYST_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPB5F1D4270066E986
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP3DFD541DD943314C
annotation: SIP5E173AB41E8A4E08
annotation: SIPC2A76D2982BE7BD3
annotation: PRO_0000327727
annotation: SIP7533D1DD17DBA212
annotation: SIPD4B8442991B0BE96
annotation: SIPB9D731C7BF593852
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/690
classified with: GO_0005737
classified with: GO_0005730
classified with: GO_0030688
classified with: GO_0030515
classified with: GO_0006364
sequence: A9UNU6-1
proteome: Unassembled WGS sequence

A9UNU6-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3871
type: Resource
database: eggNOG
comment: Eukaryota

IPR007955
type: Resource
database: InterPro
comment: Bystin

PTHR12821
type: Resource
database: PANTHER
comment: BYSTIN
signature sequence match: PANTHER PTHR12821 match 1

PTHR12821:SF0
type: Resource
database: PANTHER
comment: BYSTIN
signature sequence match: PANTHER PTHR12821:SF0 match 1

PF05291
type: Resource
database: Pfam
comment: Bystin
signature sequence match: Pfam PF05291 match 1

SIPB5F1D4270066E986
type: Structured Name
full name: Bystin

bysl
type: Gene
orf name: 17006

SIP3DFD541DD943314C
type: Function Annotation
comment: Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.

SIPC2A76D2982BE7BD3
type: Similarity Annotation
comment: Belongs to the bystin family.

PRO_0000327727
type: Chain Annotation
comment: Bystin
mass: 47686
range: 18358912035403310tt1tt414

18358912035403310tt1
type: Position
type: ExactPosition
position: 1
reference: A9UNU6-1

18358912035403310tt414
type: Position
type: ExactPosition
position: 414
reference: A9UNU6-1

SIP7533D1DD17DBA212
type: Region Annotation
comment: Disordered
range: 18358912035403310tt1tt91

18358912035403310tt91
type: Position
type: ExactPosition
position: 91
reference: A9UNU6-1

SIPD4B8442991B0BE96
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912035403310tt8tt45

18358912035403310tt8
type: Position
type: ExactPosition
position: 8
reference: A9UNU6-1

18358912035403310tt45
type: Position
type: ExactPosition
position: 45
reference: A9UNU6-1

SIPB9D731C7BF593852
type: Compositional Bias Annotation
comment: Polar residues
range: 18358912035403310tt52tt77

18358912035403310tt52
type: Position
type: ExactPosition
position: 52
reference: A9UNU6-1

18358912035403310tt77
type: Position
type: ExactPosition
position: 77
reference: A9UNU6-1

A9UNU6-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 47686
value: MSAKRNTKLRHAPLEHAYVDDKSVRRNKRSKQRGRMQDDESVDAPLNEKQAQVIARQAQLQQNEEDVSDSEQTGQPVDIDVPSDDEGQADDLAQPEDAYRHFEIDEHDEVALRAFMPAEPAQRRTLADIIMEKIQGKRTEVASQVSQTGPRELNPKVIEVYQGVGQVLSRYRSGKLPKAFKIIPRLKNWEEIVYITEPENWTAASMYAATRLFASNLKEKMAQRFYNLILLPRVRDDIAEYKRLNFHLYQAIKKAIFKPGAFFKGFLLPLCEAGDCTLREAVIIGGILVRKSIPVLHSSAAMLKMAEMPYSGATSIFLRVLLDKKYSLPFRVVDAVVAHFYRFNADHRQLPVLWHQCLLVFVQRYKEDITSEQKRALLDVLRSHNHYAITPEIRRELVQSKSRDREMPLEESSR

http://purl.uniprot.org/uniprot/A9UNU6#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UNU6#attribution-45BF8D55BAF095D71FE542F966671CCB
manual: true
evidence: ECO_0000250
source: Q13895

http://purl.uniprot.org/uniprot/A9UNU6#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UQN0
type: Protein
reviewed: true
created: 2008-07-22
modified: 2023-05-03
version: 35
mnemonic: CCD42_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPDCB52BA3DAEAED5E
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPF6EE2E71011E3241
annotation: PRO_0000343718
annotation: SIP4952607226E406DA
annotation: SIP7A70227DD16E97A8
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/175
classified with: http://purl.uniprot.org/keywords/1185
sequence: A9UQN0-1
proteome: Unassembled WGS sequence

A9UQN0-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

ENOG502QRZS
type: Resource
database: eggNOG
comment: Eukaryota

IPR025252
type: Resource
database: InterPro
comment: DUF4200

PTHR21683:SF13
type: Resource
database: PANTHER
comment: DUF4200 DOMAIN-CONTAINING PROTEIN
signature sequence match: PANTHER PTHR21683:SF13 match 1

PTHR21683
type: Resource
database: PANTHER
comment: UNCHARACTERIZED
signature sequence match: PANTHER PTHR21683 match 1

PF13863
type: Resource
database: Pfam
comment: DUF4200
signature sequence match: Pfam PF13863 match 1

SIPDCB52BA3DAEAED5E
type: Structured Name
full name: Coiled-coil domain-containing protein 42 homolog

http://purl.uniprot.org/uniprot/A9UQN0#gene-MD513EE36EF2B875A88971B760571A37ED3
type: Gene
orf name: 30998

SIPF6EE2E71011E3241
type: Similarity Annotation
comment: Belongs to the CFAP73 family.

PRO_0000343718
type: Chain Annotation
comment: Coiled-coil domain-containing protein 42 homolog
mass: 33528
range: 18358912085274670tt1tt283

18358912085274670tt1
type: Position
type: ExactPosition
position: 1
reference: A9UQN0-1

18358912085274670tt283
type: Position
type: ExactPosition
position: 283
reference: A9UQN0-1

18358912085274670tt31
type: Position
type: ExactPosition
position: 31
reference: A9UQN0-1

18358912085274670tt139
type: Position
type: ExactPosition
position: 139
reference: A9UQN0-1

18358912085274670tt174
type: Position
type: ExactPosition
position: 174
reference: A9UQN0-1

18358912085274670tt204
type: Position
type: ExactPosition
position: 204
reference: A9UQN0-1

A9UQN0-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 33528
value: MAGLREFFKETVEEKLLQQMPDDVLQQTTPATQLLEKRRELEQVERALATQKEDFHVRMATLDQRKAELERKEYQLQESLLKFDRFLKENDARRERAEQKAASENEVAQAREEQVQNLRAELRSLQERKTRNRDILQRYSIFEAFMQTVLGEYPEYNEVQDVITRYKTLVATQQDLRSRDRNNQTEIERVRREMARYKEAHRVSMLDCSNKLATLRTAKERAHTETLYWENQLSAVQGAASKRTLLLGQIKMYAYPPAHPGTCPTRTWLALTREPRCCHEPPR

http://purl.uniprot.org/uniprot/A9UQN0#attribution-DC036A124EC8E88DF072B29F6D9BB9FE
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/A9UQN0#attribution-95FAD9093B1FDB34B4D966A592657382
manual: true
evidence: ECO_0000305

A9VDW7
type: Protein
reviewed: true
created: 2009-09-01
modified: 2023-05-03
version: 66
mnemonic: CIAO1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPEA5BCD160467AAC3
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP2116864AE220C548
annotation: SIPFB44F6D5576B1A8D
annotation: PRO_0000382531
annotation: SIPD80742C1CB9D84DF
annotation: SIP293FF2165DDFBBE6
annotation: SIP15DDF1459FFCEC9D
annotation: SIP19495A7C476CE56C
annotation: SIP4E8F851DFD18CE61
annotation: SIPCE165A79B8EDF4B6
annotation: SIPDE8F04362F96D1D3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/853
classified with: GO_0097361
classified with: GO_0016226
sequence: A9VDW7-1
proteome: Unassembled WGS sequence

A9VDW7-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0645
type: Resource
database: eggNOG
comment: Eukaryota

cd00200
type: Resource
database: CDD
comment: WD40
signature sequence match: CDD cd00200 match 1

MF_03037
type: Resource
database: HAMAP
comment: ciao1
signature sequence match: HAMAP MF 03037 match 1

IPR028608
type: Resource
database: InterPro
comment: CIAO1/Cia1

PTHR19920:SF0
type: Resource
database: PANTHER
comment: CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED
signature sequence match: PANTHER PTHR19920:SF0 match 1

PTHR19920
type: Resource
database: PANTHER
comment: WD40 PROTEIN CIAO1
signature sequence match: PANTHER PTHR19920 match 1

SIPEA5BCD160467AAC3
type: Structured Name
full name: Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog

http://purl.uniprot.org/uniprot/A9VDW7#gene-MD561A00570D22E72DC9A830E5A694C554E
type: Gene
orf name: 30417

SIP2116864AE220C548
type: Function Annotation
comment: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

SIPFB44F6D5576B1A8D
type: Similarity Annotation
comment: Belongs to the WD repeat CIA1 family.

PRO_0000382531
type: Chain Annotation
comment: Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog
mass: 55378
range: 18358916162729774tt1tt506

18358916162729774tt1
type: Position
type: ExactPosition
position: 1
reference: A9VDW7-1

18358916162729774tt506
type: Position
type: ExactPosition
position: 506
reference: A9VDW7-1

SIPD80742C1CB9D84DF
type: Repeat Annotation
comment: WD 1
range: 18358916162729774tt157tt196

18358916162729774tt157
type: Position
type: ExactPosition
position: 157
reference: A9VDW7-1

18358916162729774tt196
type: Position
type: ExactPosition
position: 196
reference: A9VDW7-1

SIP293FF2165DDFBBE6
type: Repeat Annotation
comment: WD 2
range: 18358916162729774tt202tt241

18358916162729774tt202
type: Position
type: ExactPosition
position: 202
reference: A9VDW7-1

18358916162729774tt241
type: Position
type: ExactPosition
position: 241
reference: A9VDW7-1

SIP15DDF1459FFCEC9D
type: Repeat Annotation
comment: WD 3
range: 18358916162729774tt246tt281

18358916162729774tt246
type: Position
type: ExactPosition
position: 246
reference: A9VDW7-1

18358916162729774tt281
type: Position
type: ExactPosition
position: 281
reference: A9VDW7-1

SIP19495A7C476CE56C
type: Repeat Annotation
comment: WD 4
range: 18358916162729774tt282tt320

18358916162729774tt282
type: Position
type: ExactPosition
position: 282
reference: A9VDW7-1

18358916162729774tt320
type: Position
type: ExactPosition
position: 320
reference: A9VDW7-1

SIP4E8F851DFD18CE61
type: Repeat Annotation
comment: WD 5
range: 18358916162729774tt327tt366

18358916162729774tt327
type: Position
type: ExactPosition
position: 327
reference: A9VDW7-1

18358916162729774tt366
type: Position
type: ExactPosition
position: 366
reference: A9VDW7-1

SIPCE165A79B8EDF4B6
type: Repeat Annotation
comment: WD 6
range: 18358916162729774tt418tt457

18358916162729774tt418
type: Position
type: ExactPosition
position: 418
reference: A9VDW7-1

18358916162729774tt457
type: Position
type: ExactPosition
position: 457
reference: A9VDW7-1

SIPDE8F04362F96D1D3
type: Repeat Annotation
comment: WD 7
range: 18358916162729774tt469tt506

18358916162729774tt469
type: Position
type: ExactPosition
position: 469
reference: A9VDW7-1

A9VDW7-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 55378
value: MACSCLLMASMQTLPGPGAFRTENGTLYLAFQEYYEAPQDPHNMADALSQTLSNSSLSQTLLSQTLISHTFLSQTLLSNSSLSHSLTLSQNSQTLLSQTLLSQTLLSLLSLTLSHSLKTLSNSFFSLKLFSLKLLDVFSLSHTRTSTREDGGDGQDGHEDRVWDVKWSPTGAVLASSSGDQTVRLWTREARDWVCLSTLEGPQKGTIRSLSWGREGNYLAAASFDSTTCVWEKGPSGFECFATLEGHENEVKGVAFSASGDYIATWFADEEEFDCAAILAEHSQDVKAVAWHPTRDLLASCSYDNTIRFYRADPDNADWICCDTLSDNQSTVWKICFNADGSRLAAVGDDRTLRVYQAFPPGNPQGAALPAHSSIYAPCLRNTLHSAINRLVCSDFAGIVTPSASDDKWKCIATITGQHTRPIYSVDWDPETNILATAGGDNIVRLFRETAVQPDTNTPSYELIGQFQAHDQDLNGLAWAPNQPDLQHRLLATCADDGLHVGNHKS

http://purl.uniprot.org/uniprot/A9VDW7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VDW7#attribution-5BC973FD11D451CAF152E52F22669FAB
manual: true
evidence: ECO_0000255
source: MF_03037

A9UQM0
type: Protein
reviewed: true
created: 2010-03-02
modified: 2023-02-22
version: 51
mnemonic: DDRGK_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP2E1AF781A0F79615
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP38BF2C953013A2F2
annotation: SIP7B7FB8F564939A3B
annotation: PRO_0000391873
annotation: SIP57F6B09D45F0958C
annotation: SIP0C363059C24FB4B7
annotation: SIP5825C05CAFCC9525
annotation: SIPB92A7355D94EF5D7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/732
sequence: A9UQM0-1
proteome: Unassembled WGS sequence

A9UQM0-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3054
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/1.10.10.10
type: Resource
database: Gene3D
comment: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
signature sequence match: Gene3D 1.10.10.10 match 1

IPR019153
type: Resource
database: InterPro
comment: DDRGK_dom-contain

IPR036388
type: Resource
database: InterPro
comment: WH-like_DNA-bd_sf

IPR036390
type: Resource
database: InterPro
comment: WH_DNA-bd_sf

PTHR48176
type: Resource
database: PANTHER
comment: DDRGK DOMAIN-CONTAINING PROTEIN 1
signature sequence match: PANTHER PTHR48176 match 1

PTHR48176:SF1
type: Resource
database: PANTHER
comment: DDRGK DOMAIN-CONTAINING PROTEIN 1
signature sequence match: PANTHER PTHR48176:SF1 match 1

PF09756
type: Resource
database: Pfam
comment: DDRGK
signature sequence match: Pfam PF09756 match 1

SM01128
type: Resource
database: SMART
comment: DDRGK
signature sequence match: SMART SM01128 match 1

SSF46785
type: Resource
database: SUPFAM
comment: Winged helix' DNA-binding domain
signature sequence match: SUPFAM SSF46785 match 1

SIP2E1AF781A0F79615
type: Structured Name
full name: DDRGK domain-containing protein 1

http://purl.uniprot.org/uniprot/A9UQM0#gene-MD55BAD48F91320C87B2F37CA648F9BF42A
type: Gene
orf name: 22450

SIP38BF2C953013A2F2
type: Similarity Annotation
comment: Belongs to the DDRGK1 family.

18358912085209134tt1
type: Position
type: ExactPosition
position: 1
reference: A9UQM0-1

18358912085209134tt27
type: Position
type: ExactPosition
position: 27
reference: A9UQM0-1

PRO_0000391873
type: Chain Annotation
comment: DDRGK domain-containing protein 1
mass: 30579
range: 18358912085209134tt28tt293

18358912085209134tt28
type: Position
type: ExactPosition
position: 28
reference: A9UQM0-1

18358912085209134tt293
type: Position
type: ExactPosition
position: 293
reference: A9UQM0-1

SIP57F6B09D45F0958C
type: Region Annotation
comment: Disordered
range: 18358912085209134tt30tt151

18358912085209134tt30
type: Position
type: ExactPosition
position: 30
reference: A9UQM0-1

18358912085209134tt151
type: Position
type: ExactPosition
position: 151
reference: A9UQM0-1

SIP0C363059C24FB4B7
type: Region Annotation
comment: Disordered
range: 18358912085209134tt273tt293

18358912085209134tt273
type: Position
type: ExactPosition
position: 273
reference: A9UQM0-1

SIP5825C05CAFCC9525
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912085209134tt30tt45

18358912085209134tt45
type: Position
type: ExactPosition
position: 45
reference: A9UQM0-1

SIPB92A7355D94EF5D7
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912085209134tt68tt151

18358912085209134tt68
type: Position
type: ExactPosition
position: 68
reference: A9UQM0-1

A9UQM0-1
type: Simple Sequence
modified: 2008-02-05
version: 1
precursor: true
mass: 33510
value: MWGPLIYALLGLAIVAAAFLFVRRSQAKEVVPVADDDDKENGAAADEVNPRQAGDQGHTDDEDGEEGNEGLKNFMYDENGKKLGVKKARKLQEKEERRRRNEEMAQAREQAKLLQHQEEEERKEREAEEAEDERQREAELEREREAQRQKELEEYNSLKSMFVVEESGELDVDHEAQAQSLLNEFVSFIKEKKVVQLEDLAAHFGLKTQDTIERIQQLEAEGRLTGLTDDRGKYIFISEEELSEVVKFIERRGRITIAELMDNSNRLISLSETDVEFPGDEPAPADVDETTTA

http://purl.uniprot.org/uniprot/A9UQM0#attribution-DC036A124EC8E88DF072B29F6D9BB9FE
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/A9UQM0#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9V767
type: Protein
reviewed: true
created: 2010-03-23
modified: 2023-02-22
version: 63
mnemonic: DRE2_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP36883F92CAEBA89D
alternative name: SIPCE816FC94C8C374F
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPA9A2EB47530D67CC
annotation: SIPA4D83A43FD5750AC
annotation: SIPCEBBA87A46816C0D
annotation: SIP411BBA9F859D8D31
annotation: SIP738F2313765D390C
annotation: SIP28EBB360E46A594B
annotation: SIP38A68B8A78616CDC
annotation: SIP4EB64E9002F41480
annotation: SIP72A450E5C6B96B01
annotation: PRO_0000392412
annotation: SIPB80E57B200EB91EA
annotation: SIPE5C6C46C3A7C2FCA
annotation: SIP589A5D5290D649B0
annotation: SIP8DAE1A4ACD2CBAD4
annotation: SIP624A4BB994F52AE0
annotation: SIP560634F734D49B55
annotation: SIP1A4E54A92E9E7A20
annotation: SIPF68979C879E8895A
annotation: SIPE0AD29498B360530
annotation: SIP321D66BBA5D8B983
annotation: SIP9E2A3ADAD3FAE0E0
annotation: SIP193D338E3FA76560
annotation: SIPA3E835C684859FE2
annotation: SIPFCFFDAF773C08634
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005758
classified with: GO_0051537
classified with: GO_0051539
classified with: GO_0009055
classified with: GO_0046872
classified with: GO_0016226
sequence: A9V767-1
proteome: Unassembled WGS sequence

A9V767-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG4020
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.40.50.150
type: Resource
database: Gene3D
comment: Vaccinia Virus protein VP39
signature sequence match: Gene3D 3.40.50.150 match 1

MF_03115
type: Resource
database: HAMAP
comment: Anamorsin
signature sequence match: HAMAP MF 03115 match 1

IPR007785
type: Resource
database: InterPro
comment: Anamorsin

IPR046408
type: Resource
database: InterPro
comment: CIAPIN1

IPR029063
type: Resource
database: InterPro
comment: SAM-dependent_MTases_sf

PTHR13273
type: Resource
database: PANTHER
comment: ANAMORSIN
signature sequence match: PANTHER PTHR13273 match 1

PTHR13273:SF14
type: Resource
database: PANTHER
comment: ANAMORSIN
signature sequence match: PANTHER PTHR13273:SF14 match 1

PF05093
type: Resource
database: Pfam
comment: CIAPIN1
signature sequence match: Pfam PF05093 match 1

SSF53335
type: Resource
database: SUPFAM
comment: S-adenosyl-L-methionine-dependent methyltransferases
signature sequence match: SUPFAM SSF53335 match 1

SIP36883F92CAEBA89D
type: Structured Name
full name: Anamorsin homolog

SIPCE816FC94C8C374F
type: Structured Name
full name: Fe-S cluster assembly protein DRE2 homolog

http://purl.uniprot.org/uniprot/A9V767#gene-MD525AC2C555A7937CBCD694C62A9C7A59E
type: Gene
orf name: 33738

SIPA9A2EB47530D67CC
type: Function Annotation
comment: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.

SIP411BBA9F859D8D31
type: Subunit Annotation
comment: Monomer.

SIP28EBB360E46A594B
type: Domain Annotation
comment: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.

SIP38A68B8A78616CDC
type: Domain Annotation
comment: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.

SIP4EB64E9002F41480
type: Domain Annotation
comment: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

SIP72A450E5C6B96B01
type: Similarity Annotation
comment: Belongs to the anamorsin family.

PRO_0000392412
type: Chain Annotation
comment: Anamorsin homolog
mass: 29474
range: 18358915942463278tt1tt282

18358915942463278tt1
type: Position
type: ExactPosition
position: 1
reference: A9V767-1

18358915942463278tt282
type: Position
type: ExactPosition
position: 282
reference: A9V767-1

SIPB80E57B200EB91EA
type: Region Annotation
comment: N-terminal SAM-like domain
range: 18358915942463278tt1tt140

18358915942463278tt140
type: Position
type: ExactPosition
position: 140
reference: A9V767-1

SIPE5C6C46C3A7C2FCA
type: Region Annotation
comment: Linker
range: 18358915942463278tt141tt192

18358915942463278tt141
type: Position
type: ExactPosition
position: 141
reference: A9V767-1

18358915942463278tt192
type: Position
type: ExactPosition
position: 192
reference: A9V767-1

SIP589A5D5290D649B0
type: Region Annotation
comment: Fe-S binding site A
range: 18358915942463278tt203tt219

18358915942463278tt203
type: Position
type: ExactPosition
position: 203
reference: A9V767-1

18358915942463278tt219
type: Position
type: ExactPosition
position: 219
reference: A9V767-1

SIP8DAE1A4ACD2CBAD4
type: Region Annotation
comment: Fe-S binding site B
range: 18358915942463278tt243tt257

18358915942463278tt243
type: Position
type: ExactPosition
position: 243
reference: A9V767-1

18358915942463278tt257
type: Position
type: ExactPosition
position: 257
reference: A9V767-1

SIP624A4BB994F52AE0
type: Motif Annotation
comment: Cx2C motif 1
range: 18358915942463278tt243tt246

18358915942463278tt246
type: Position
type: ExactPosition
position: 246
reference: A9V767-1

SIP560634F734D49B55
type: Motif Annotation
comment: Cx2C motif 2
range: 18358915942463278tt254tt257

18358915942463278tt254
type: Position
type: ExactPosition
position: 254
reference: A9V767-1

18358915942463278tt214
type: Position
type: ExactPosition
position: 214
reference: A9V767-1

18358915942463278tt217
type: Position
type: ExactPosition
position: 217
reference: A9V767-1

A9V767-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 29474
value: MADLQGKAVLTIAVPEAKADQIEAEILRLRAATTEAGSVQLEQFDRLEQVFLAPSSYDVIFSGHIALPAKSHADSALAKLAAALKPGGRLALRESLNSRNETALRSALTMGGFVNVQVSTSEHALEAHADKPVYEVGAAAPLKLSFAKKKQSGAAAPAAQVAEVWTIATDDFDDDDLLENDGDELLDAEDLALATTAPEGDDCEVGAGGKRRACKNCTCGRADAEAEQAAKPTLTGPLPASSCGNCYLGDAFRCASCPYLGMPAFKPGEKVTLSDRQLKADA

http://purl.uniprot.org/uniprot/A9V767#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V767#attribution-9E45DBD3611EC728E45A7B5111E043BD
manual: true
evidence: ECO_0000255
source: MF_03115

A9V549
type: Protein
reviewed: true
created: 2009-03-24
modified: 2023-05-03
version: 62
mnemonic: EIF3A_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP232CA75F4748A948
alternative name: SIPDCA93E927319CBE5
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP81FC3B7513910048
annotation: SIPB59A95377AD4EE42
annotation: SIPDBABD0CC4B957660
annotation: SIP0B59931A0F72BFA9
annotation: PRO_0000366372
annotation: SIP04267FCCB16DE9D9
annotation: SIP88C5BDCECFD35F21
annotation: SIP6122A866573CF5C4
annotation: SIPB336DC708A8A532A
annotation: SIPCEC9AD570761F163
annotation: SIP6CC8AB8A1D7E2FA2
annotation: SIP4C6A6C808BC5F5B2
annotation: SIP3D04AC5634403330
annotation: SIPB88208F3ADF5110B
annotation: SIP40CF95632FB95E5C
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/175
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/396
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/694
classified with: GO_0016282
classified with: GO_0033290
classified with: GO_0071540
classified with: GO_0071541
classified with: GO_0043614
classified with: GO_0003729
classified with: GO_0003743
classified with: GO_0001732
classified with: GO_0002188
sequence: A9V549-1
proteome: Unassembled WGS sequence

A9V549-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2072
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/4.10.860.10
type: Resource
database: Gene3D
comment: UVR domain
signature sequence match: Gene3D 4.10.860.10 match 1

MF_03000
type: Resource
database: HAMAP
comment: eIF3a
signature sequence match: HAMAP MF 03000 match 1

IPR027512
type: Resource
database: InterPro
comment: EIF3A

IPR000717
type: Resource
database: InterPro
comment: PCI_dom

PTHR14005:SF0
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A
signature sequence match: PANTHER PTHR14005:SF0 match 1

PTHR14005
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT
signature sequence match: PANTHER PTHR14005 match 1

PF01399
type: Resource
database: Pfam
comment: PCI
signature sequence match: Pfam PF01399 match 1

PS50250
type: Resource
database: PROSITE
comment: PCI
signature sequence match: PROSITE PS50250 match 1

SIP232CA75F4748A948
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit A
short name: eIF3a

SIPDCA93E927319CBE5
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit 10

http://purl.uniprot.org/uniprot/A9V549#gene-MD54D174C6B0FD251B2CB08A80CAB3F66CE
type: Gene
orf name: 33388

SIP81FC3B7513910048
type: Function Annotation
comment: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

SIPB59A95377AD4EE42
type: Subunit Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

SIP0B59931A0F72BFA9
type: Similarity Annotation
comment: Belongs to the eIF-3 subunit A family.

PRO_0000366372
type: Chain Annotation
comment: Eukaryotic translation initiation factor 3 subunit A
mass: 122105
range: 18358915908778286tt1tt1052

18358915908778286tt1
type: Position
type: ExactPosition
position: 1
reference: A9V549-1

18358915908778286tt1052
type: Position
type: ExactPosition
position: 1052
reference: A9V549-1

SIP04267FCCB16DE9D9
type: Domain Extent Annotation
comment: PCI
range: 18358915908778286tt325tt505

18358915908778286tt325
type: Position
type: ExactPosition
position: 325
reference: A9V549-1

18358915908778286tt505
type: Position
type: ExactPosition
position: 505
reference: A9V549-1

SIP88C5BDCECFD35F21
type: Region Annotation
comment: Disordered
range: 18358915908778286tt570tt606

18358915908778286tt570
type: Position
type: ExactPosition
position: 570
reference: A9V549-1

18358915908778286tt606
type: Position
type: ExactPosition
position: 606
reference: A9V549-1

SIP6122A866573CF5C4
type: Region Annotation
comment: Disordered
range: 18358915908778286tt793tt1052

18358915908778286tt793
type: Position
type: ExactPosition
position: 793
reference: A9V549-1

18358915908778286tt568
type: Position
type: ExactPosition
position: 568
reference: A9V549-1

18358915908778286tt712
type: Position
type: ExactPosition
position: 712
reference: A9V549-1

18358915908778286tt769
type: Position
type: ExactPosition
position: 769
reference: A9V549-1

18358915908778286tt882
type: Position
type: ExactPosition
position: 882
reference: A9V549-1

SIP6CC8AB8A1D7E2FA2
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358915908778286tt570tt595

18358915908778286tt595
type: Position
type: ExactPosition
position: 595
reference: A9V549-1

SIP4C6A6C808BC5F5B2
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358915908778286tt793tt872

18358915908778286tt872
type: Position
type: ExactPosition
position: 872
reference: A9V549-1

SIP3D04AC5634403330
type: Compositional Bias Annotation
comment: Polar residues
range: 18358915908778286tt873tt921

18358915908778286tt873
type: Position
type: ExactPosition
position: 873
reference: A9V549-1

18358915908778286tt921
type: Position
type: ExactPosition
position: 921
reference: A9V549-1

SIPB88208F3ADF5110B
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358915908778286tt925tt968

18358915908778286tt925
type: Position
type: ExactPosition
position: 925
reference: A9V549-1

18358915908778286tt968
type: Position
type: ExactPosition
position: 968
reference: A9V549-1

SIP40CF95632FB95E5C
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358915908778286tt982tt996

18358915908778286tt982
type: Position
type: ExactPosition
position: 982
reference: A9V549-1

18358915908778286tt996
type: Position
type: ExactPosition
position: 996
reference: A9V549-1

A9V549-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 122105
value: MSMNKFFQPKNALKRAEDLEAVGKPNLALETLHDLLNSSKHKKQWTAVHEEIMIKFLDLCMQLKRAPEAKDGLYQFKIVTGTSAVNSLEKVVRYYLKTAEDKVAEAWQQSQLRDATNVNDEIDDLEEAQTPEQVLLAAVSADGETERANRVQLMPWLRYLWEAYRAVLELLRHHSKMEHAYHATARQAMRFCHQYERRNEFRRLCNMLSLHLNQWRTPYQSKSGQAGIDINNPQTIQYSLDTRFELISYAGKLEQWQEAFRAMEEVTGLLDSAPEKPSPPVWGIYYHKLAQIFWRSKDYAFHAAAWHQMFDNAIRNAKSFNRDDIQYAASAVLLASLTVPLANLDTMVKPMEGYLPEVRASRQQRLAGLLGLSRMPSRDELLQYMFDLNVMTYVHPALKDLYNLVEDEFDPLQLSQKAAPVLEFLKSHEQFAQYVTPLKYILLLRLLKQLSQLYSSLKLERCFKLASFMTPEECEEVLVHAVQDKVLQLRIDHARGSLHFNNNIFAFNERQVNDGPKLQNLQAEMMNGQLTTLSRRLYTAINMIKPAVVQESQMGVKAINRIKDEVAREHVSNLSRRDEIEKQKEELEQSRRRRHQEQMQKHHQNQMQVRQKMAEAVKKNQEELERQKLQLQREEIERQKALEALNDVSSSSAGQKVVQALNKSDLGTKITAQDIHKMAYEQQKKDARERQERLRAEEKRLDHMERAKRLREIPRRKEHIAAMSEQNAKWHTELQSARLEKARVDHAKALGLKELLKAFAPDKDAYIEEKTAERRKEYMAKLDDFKQRMQEQKIRLEREERERKREEKRRAEEEEQRRIKQEEEDRKQREREAKREQERQEQLKLEEAERKKMEEATKLQRQREEQVRAREQEKLSNLSAQTSQPTWKRSARSDAPTTAAPSSMRVSSWKGDASDDSGRSQPFRPSRGGERDSGRSFSGLGDRGDRAPRDTGRSFSGLGDRGDRAPRDTGRSFSGLGDRAPRDFSGRSEPSRSGPRDFSGRSEAGRTSGERRALHVPSGGADKPSGDNVWRSSRGAGSERRVNIPSRGDDKN

http://purl.uniprot.org/uniprot/A9V549#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V549#attribution-6316FED230A849F64B93AEAFBBAD99BC
manual: true
evidence: ECO_0000255
source: MF_03000

http://purl.uniprot.org/uniprot/A9V549#attribution-A19FBB9D1D4F821617B3304C80C97E77
manual: true
evidence: ECO_0000255
source: PRU01185

A9UQS1
type: Protein
reviewed: true
created: 2009-03-03
modified: 2023-05-03
version: 71
mnemonic: EIF3E_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP5E01CB43CA96A610
alternative name: SIP1CF0C13E20A14CAB
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP7BF7F1C381777FD3
annotation: SIP23465C8280BB8FA4
annotation: SIPCBB22A0ED1538823
annotation: SIP96523F87F587D0AE
annotation: PRO_0000365994
annotation: SIP1351A96463AB9C20
annotation: SIPC0763E1B10A99FE6
annotation: SIPA6A7C5FAD9FC8995
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/396
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0016282
classified with: GO_0033290
classified with: GO_0005852
classified with: GO_0071540
classified with: GO_0005634
classified with: GO_0003743
classified with: GO_0001732
classified with: GO_0006413
sequence: A9UQS1-1
proteome: Unassembled WGS sequence

A9UQS1-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2758
type: Resource
database: eggNOG
comment: Eukaryota

cd21378
type: Resource
database: CDD
comment: eIF3E
signature sequence match: CDD cd21378 match 1

MF_03004
type: Resource
database: HAMAP
comment: eIF3e
signature sequence match: HAMAP MF 03004 match 1

IPR016650
type: Resource
database: InterPro
comment: eIF3e

IPR019010
type: Resource
database: InterPro
comment: eIF3e_N

PTHR10317
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E
signature sequence match: PANTHER PTHR10317 match 1

PTHR10317:SF0
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E
signature sequence match: PANTHER PTHR10317:SF0 match 1

PF09440
type: Resource
database: Pfam
comment: eIF3_N
signature sequence match: Pfam PF09440 match 1

PIRSF016255
type: Resource
database: PIRSF
comment: eIF3e_su6
signature sequence match: PIRSF PIRSF016255 match 1

SM01186
type: Resource
database: SMART
comment: eIF3_N
signature sequence match: SMART SM01186 match 1

SIP5E01CB43CA96A610
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit E
short name: eIF3e

SIP1CF0C13E20A14CAB
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit 6

http://purl.uniprot.org/uniprot/A9UQS1#gene-MD50CA7B851CECDEAEA931D1E14F1374F2F
type: Gene
orf name: 13685

SIP7BF7F1C381777FD3
type: Function Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

SIP23465C8280BB8FA4
type: Subunit Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

SIP96523F87F587D0AE
type: Similarity Annotation
comment: Belongs to the eIF-3 subunit E family.

PRO_0000365994
type: Chain Annotation
comment: Eukaryotic translation initiation factor 3 subunit E
mass: 55760
range: 18358912085602606tt1tt485

18358912085602606tt1
type: Position
type: ExactPosition
position: 1
reference: A9UQS1-1

18358912085602606tt485
type: Position
type: ExactPosition
position: 485
reference: A9UQS1-1

SIP1351A96463AB9C20
type: Domain Extent Annotation
comment: PCI
range: 18358912085602606tt219tt391

18358912085602606tt219
type: Position
type: ExactPosition
position: 219
reference: A9UQS1-1

18358912085602606tt391
type: Position
type: ExactPosition
position: 391
reference: A9UQS1-1

SIPC0763E1B10A99FE6
type: Region Annotation
comment: Disordered
range: 18358912085602606tt444tt485

18358912085602606tt444
type: Position
type: ExactPosition
position: 444
reference: A9UQS1-1

SIPA6A7C5FAD9FC8995
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912085602606tt450tt485

18358912085602606tt450
type: Position
type: ExactPosition
position: 450
reference: A9UQS1-1

A9UQS1-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 55760
value: MAAHDLTQAICQNLDPHLILPLLDHCVDLDIYNEADLKRAKMQVLSRTRLIEQALELADATEKKDLDARMRSISEEEKTWEKQLEPVFEMFENDEVLSIIEATKNKDSLLSELEPYGFTENTADLLYHGSKFYFDRGQYDLAHGLLYNYRAVSTDDKLKFTALWGKLAAAILSGNWQTAQEDMYLLLEYIDGGKNELTAVEQLQQRNWLLHWSLFVFFNQPDGPDGIVDLFMNKETCTNAMQTIAPHLFRYATAVAIMSRRKKRDVMWEFVGIARQDKDLGDDPVVGFLVSLIKDFDFVTAEEKLQQCREVLSKDYFLAEMTDEFINTAQLYLFEVYLRVHSRVSIKNAATRLGKSEDDAEEWLVKLIRDAKLDAQIDPASGEIHITKPVTTVYQHVLDRTKNLQYRTYVIVESLHHLHPNGAFHHSNSSIPALFRRMMNEQLQGGGKSNKKGDYKKGDYKKGGDFKKGGDFKKGGDHKKRAWVK

http://purl.uniprot.org/uniprot/A9UQS1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UQS1#attribution-8FC96F3563DFA20FB5BD6210C546FE8C
manual: true
evidence: ECO_0000255
source: MF_03004

http://purl.uniprot.org/uniprot/A9UQS1#attribution-A19FBB9D1D4F821617B3304C80C97E77
manual: true
evidence: ECO_0000255
source: PRU01185

A9V3P1
type: Protein
reviewed: true
created: 2009-03-03
modified: 2023-02-22
version: 68
mnemonic: EIF3H_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPBD4DBC9DC88FC463
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP9A6604537B846C73
annotation: SIP126CC3ABD1465648
annotation: SIP4AA9B3B79F67554A
annotation: SIP8F2E38F4D829AE82
annotation: PRO_0000365214
annotation: SIP9D25A145183AB439
annotation: SIPD08AB7FFE04D7A90
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/396
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0016282
classified with: GO_0033290
classified with: GO_0005852
classified with: GO_0042788
classified with: GO_0008237
classified with: GO_0003743
classified with: GO_0001732
sequence: A9V3P1-1
proteome: Unassembled WGS sequence

A9V3P1-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1560
type: Resource
database: eggNOG
comment: Eukaryota

cd08065
type: Resource
database: CDD
comment: MPN_eIF3h
signature sequence match: CDD cd08065 match 1

http://purl.uniprot.org/gene3d/3.40.140.10
type: Resource
database: Gene3D
comment: Cytidine Deaminase, domain 2
signature sequence match: Gene3D 3.40.140.10 match 1

MF_03007
type: Resource
database: HAMAP
comment: eIF3h
signature sequence match: HAMAP MF 03007 match 1

IPR027524
type: Resource
database: InterPro
comment: eIF3h

IPR045810
type: Resource
database: InterPro
comment: eIF3h_C

IPR000555
type: Resource
database: InterPro
comment: JAMM/MPN+_dom

IPR037518
type: Resource
database: InterPro
comment: MPN

PTHR10410
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED
signature sequence match: PANTHER PTHR10410 match 1

PTHR10410:SF3
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H
signature sequence match: PANTHER PTHR10410:SF3 match 1

PF19445
type: Resource
database: Pfam
comment: eIF3h_C
signature sequence match: Pfam PF19445 match 1

PF01398
type: Resource
database: Pfam
comment: JAB
signature sequence match: Pfam PF01398 match 1

SM00232
type: Resource
database: SMART
comment: JAB_MPN
signature sequence match: SMART SM00232 match 1

PS50249
type: Resource
database: PROSITE
comment: MPN
signature sequence match: PROSITE PS50249 match 1

SIPBD4DBC9DC88FC463
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit H
short name: eIF3h

http://purl.uniprot.org/uniprot/A9V3P1#gene-MD55BC5D025F7852D3F8F280FC7CD729CBA
type: Gene
orf name: 9558

SIP9A6604537B846C73
type: Function Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

SIP126CC3ABD1465648
type: Subunit Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

SIP8F2E38F4D829AE82
type: Similarity Annotation
comment: Belongs to the eIF-3 subunit H family.

PRO_0000365214
type: Chain Annotation
comment: Eukaryotic translation initiation factor 3 subunit H
mass: 39843
range: 18358915877056814tt1tt354

18358915877056814tt1
type: Position
type: ExactPosition
position: 1
reference: A9V3P1-1

18358915877056814tt354
type: Position
type: ExactPosition
position: 354
reference: A9V3P1-1

SIP9D25A145183AB439
type: Domain Extent Annotation
comment: MPN
range: 18358915877056814tt33tt174

18358915877056814tt33
type: Position
type: ExactPosition
position: 33
reference: A9V3P1-1

18358915877056814tt174
type: Position
type: ExactPosition
position: 174
reference: A9V3P1-1

SIPD08AB7FFE04D7A90
type: Region Annotation
comment: Disordered
range: 18358915877056814tt1tt28

18358915877056814tt28
type: Position
type: ExactPosition
position: 28
reference: A9V3P1-1

A9V3P1-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 39843
value: MATRQPYQKKFQSRDQREQTSSQQAPNSVVKQVTVDALVVMKIIKHARENPHEPVRGPLLGLSQLADASKPGEDALLEVTNCFPTPRVSDDDDDSIVQQYQVQMMRWLREVNVDHMNVGWYQAADMGTFFDEDVAAVQFQHQRHMAESVVLIYDPVLTLQGTLSLSAFRLSNKAMELFSTDSFNPKAVREAGLTYRTVFEKVPVTIRASSMARLLIPELSANLDQSEIFDRMDLNATSFMSRNIKLLMEGIDDLSQEAYKFQQYHRNATKAKASLDAQLEARRAENEQLRAKGLPEKSEAELVANHKTPTPPSRLGSLLVTAQINTFCKQVSDFSGQSFGKLYIAKATQPEAEE

http://purl.uniprot.org/uniprot/A9V3P1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V3P1#attribution-1A938BD482270576963814DA9F039F70
manual: true
evidence: ECO_0000255
source: MF_03007

http://purl.uniprot.org/uniprot/A9V3P1#attribution-52D21B6CC06AC361CED1DF8DBF49D80A
manual: true
evidence: ECO_0000255
source: PRU01182

A9VCY6
type: Protein
reviewed: true
created: 2009-03-03
modified: 2023-02-22
version: 64
mnemonic: EIF3L_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPEC571B787D65DF2F
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP52AA3B9E7EC2D0A2
annotation: SIPD154C91676AEF98C
annotation: SIPF12B2247CC47EB6C
annotation: SIPE5F559177F0C98AB
annotation: PRO_0000364234
annotation: SIPB434342141261ABF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/396
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0016282
classified with: GO_0033290
classified with: GO_0005852
classified with: GO_0003743
classified with: GO_0001732
classified with: GO_0006413
sequence: A9VCY6-1
proteome: Unassembled WGS sequence

A9VCY6-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3677
type: Resource
database: eggNOG
comment: Eukaryota

MF_03011
type: Resource
database: HAMAP
comment: eIF3l
signature sequence match: HAMAP MF 03011 match 1

IPR019382
type: Resource
database: InterPro
comment: eIF3l

PTHR13242
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3
signature sequence match: PANTHER PTHR13242 match 1

PTHR13242:SF0
type: Resource
database: PANTHER
comment: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L
signature sequence match: PANTHER PTHR13242:SF0 match 1

PF10255
type: Resource
database: Pfam
comment: Paf67
signature sequence match: Pfam PF10255 match 1

SIPEC571B787D65DF2F
type: Structured Name
full name: Eukaryotic translation initiation factor 3 subunit L
short name: eIF3l

http://purl.uniprot.org/uniprot/A9VCY6#gene-MD5E0D46C7641BFE8E714FBDE698E39435F
type: Gene
orf name: 39212

SIP52AA3B9E7EC2D0A2
type: Function Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

SIPD154C91676AEF98C
type: Subunit Annotation
comment: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

SIPE5F559177F0C98AB
type: Similarity Annotation
comment: Belongs to the eIF-3 subunit L family.

PRO_0000364234
type: Chain Annotation
comment: Eukaryotic translation initiation factor 3 subunit L
mass: 59924
range: 18358916146083374tt1tt512

18358916146083374tt1
type: Position
type: ExactPosition
position: 1
reference: A9VCY6-1

18358916146083374tt512
type: Position
type: ExactPosition
position: 512
reference: A9VCY6-1

SIPB434342141261ABF
type: Domain Extent Annotation
comment: PCI
range: 18358916146083374tt291tt477

18358916146083374tt291
type: Position
type: ExactPosition
position: 291
reference: A9VCY6-1

18358916146083374tt477
type: Position
type: ExactPosition
position: 477
reference: A9VCY6-1

A9VCY6-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 59924
value: MEQETFEEQEITVADINANVPQEVQNYLRSFNKAIQEKSLKEIEEHYEYKWRRTTDQYFKDSRWPEPVYIQAMFEQEGQEDSYFVSLYPELYYRDVYYRSSNTNIEITVEDRHASYDHYIELINMFVEPDAPLDLELPNKWLWDMIDEFLYQFQDFVIFRSRVDDAKTESDYQEIAERPNAWNVTIVLNALHSLILKSEINEQLEAYRSGQNPTEMAGAFGKSSLYKMLGCFSLVGLVRLQCHLGDYRQALQIMKNVDLDRRFIFSLVPACNVSLHYHLGFCYLMLRRYQDAFRLFESILIQMASHRGPGHYDGGRKRDTIVCLLALAYSLLPQRLERSVEHLMNEKEGENIRKIQSGEGADEAINHLLLRGAPRFLCPFLADPQQPPEEDVLKAESERQLELFKQEAKQLILLGQIRSYLKLYTRMKLEKLAKFLELTVPQLRSMLHSFKHKMSQIVHTPGGEPLAGERQFTDSVDFYVDGDEICIATMTVKKSYGDDFLTASLKMVTSNR

http://purl.uniprot.org/uniprot/A9VCY6#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VCY6#attribution-A60E36E15C42C5B1D0574B5E2F74AA0E
manual: true
evidence: ECO_0000255
source: MF_03011

http://purl.uniprot.org/uniprot/A9VCY6#attribution-A19FBB9D1D4F821617B3304C80C97E77
manual: true
evidence: ECO_0000255
source: PRU01185

A9V2Y9
type: Protein
reviewed: true
created: 2010-05-18
modified: 2023-09-13
version: 74
mnemonic: ENOPH_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP9C3CC20D0C9F50B7
alternative name: SIPD21595BF0E30805E
enzyme: http://purl.uniprot.org/enzyme/3.1.3.77
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP8EFDE83CA3D455B2
annotation: SIPAC7A3056EB59FF87
annotation: SIP6664F1C10B469C80
annotation: SIP1E65C9C4F1F772CB
annotation: SIP64F35FDA370D77C6
annotation: SIP9EE564AA27BF6760
annotation: SIPAD820B0A55CCCBE9
annotation: SIP023E3E726DDBA6BD
annotation: PRO_0000394018
annotation: SIP9D07B056E844C27E
annotation: SIPB6B22FD1EFB5E2B2
annotation: SIP1A68494BCEABA8E3
annotation: SIPC2ABABBE34A9CFE0
annotation: SIPBB5037A57BF7CEF6
annotation: SIP555CF70A67F593DA
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005634
classified with: GO_0043715
classified with: GO_0043716
classified with: GO_0043874
classified with: GO_0000287
classified with: GO_0019509
classified with: GO_0019284
sequence: A9V2Y9-1
proteome: Unassembled WGS sequence

A9V2Y9-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2630
type: Resource
database: eggNOG
comment: Eukaryota

cd01629
type: Resource
database: CDD
comment: HAD_EP
signature sequence match: CDD cd01629 match 1

http://purl.uniprot.org/gene3d/3.40.50.1000
type: Resource
database: Gene3D
comment: HAD superfamily/HAD-like
signature sequence match: Gene3D 3.40.50.1000 match 1

MF_03117
type: Resource
database: HAMAP
comment: Salvage_MtnC_euk
signature sequence match: HAMAP MF 03117 match 1

IPR023943
type: Resource
database: InterPro
comment: Enolase-ppase_E1

IPR027511
type: Resource
database: InterPro
comment: ENOPH1_eukaryotes

IPR036412
type: Resource
database: InterPro
comment: HAD-like_sf

IPR023214
type: Resource
database: InterPro
comment: HAD_sf

TIGR01691
type: Resource
database: NCBIfam
comment: enolase-ppase
signature sequence match: NCBIfam TIGR01691 match 1

PTHR20371
type: Resource
database: PANTHER
comment: ENOLASE-PHOSPHATASE E1
signature sequence match: PANTHER PTHR20371 match 1

PTHR20371:SF1
type: Resource
database: PANTHER
comment: ENOLASE-PHOSPHATASE E1
signature sequence match: PANTHER PTHR20371:SF1 match 1

SFLDF00044
type: Resource
database: SFLD
comment: enolase-phosphatase
signature sequence match: SFLD SFLDF00044 match 1

SFLDS00003
type: Resource
database: SFLD
comment: Haloacid_Dehalogenase
signature sequence match: SFLD SFLDS00003 match 1

SSF56784
type: Resource
database: SUPFAM
comment: HAD-like
signature sequence match: SUPFAM SSF56784 match 1

SIP9C3CC20D0C9F50B7
type: Structured Name
full name: Enolase-phosphatase E1
ec name: 3.1.3.77

SIPD21595BF0E30805E
type: Structured Name
full name: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

http://purl.uniprot.org/uniprot/A9V2Y9#gene-MD58ABDEFDC2442A5F839D47F5979E84218
type: Gene
orf name: 26645

SIP8EFDE83CA3D455B2
type: Function Annotation
comment: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

SIP6664F1C10B469C80
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIP9EE564AA27BF6760
type: Subunit Annotation
comment: Monomer.

SIP023E3E726DDBA6BD
type: Similarity Annotation
comment: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.

PRO_0000394018
type: Chain Annotation
comment: Enolase-phosphatase E1
mass: 32219
range: 18358915860871470tt1tt301

18358915860871470tt1
type: Position
type: ExactPosition
position: 1
reference: A9V2Y9-1

18358915860871470tt301
type: Position
type: ExactPosition
position: 301
reference: A9V2Y9-1

SIP9D07B056E844C27E
type: Region Annotation
comment: Disordered
range: 18358915860871470tt273tt301

18358915860871470tt273
type: Position
type: ExactPosition
position: 273
reference: A9V2Y9-1

18358915860871470tt22
type: Position
type: ExactPosition
position: 22
reference: A9V2Y9-1

18358915860871470tt24
type: Position
type: ExactPosition
position: 24
reference: A9V2Y9-1

18358915860871470tt163
type: Position
type: ExactPosition
position: 163
reference: A9V2Y9-1

18358915860871470tt164
type: Position
type: ExactPosition
position: 164
reference: A9V2Y9-1

18358915860871470tt197
type: Position
type: ExactPosition
position: 197
reference: A9V2Y9-1

18358915860871470tt222
type: Position
type: ExactPosition
position: 222
reference: A9V2Y9-1

substrate

A9V2Y9-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 32219
value: MANSTDETATTTLAPAPCFLFDIEGTTTSISFVHEVLFPYARNQVEAFLAAHWDTDAVKADVDKLREQVSGCGKRSVADEAGPKEHGAEAASRLCASRPILLNLLEKIILTWPLVPTAHPLLELGHIWKDAYTSGNVKGHIYEDVVPAFQRLTEAGAQLYIYSSGSIAAQKLLFGHSEAGDLQPYLSGYFDTTTGPKRDAASYSDIAAAIGVTPQSIIFLSDRIEECRAASAAAMRTALVVRPGNAPLSEAERTEFPILHDFTGLRGAKFTQAQAGDTEAKRSASGDGALAAKKAPPTHDF

http://purl.uniprot.org/uniprot/A9V2Y9#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V2Y9#attribution-6E29BBE7CD36CFE0CFF5EBFE7104B934
manual: true
evidence: ECO_0000255
source: MF_03117

A9VB27
type: Protein
reviewed: true
created: 2011-01-11
modified: 2023-02-22
version: 70
mnemonic: FEN1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPD0F3B4537BEF6488
alternative name: SIPD6CD844568711308
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPA4EAD412BEB552B1
annotation: SIP1FA7150ABEF11412
annotation: SIP4B3ED02016B8608C
annotation: SIPC0EEBAB2CA08D3BD
annotation: SIP84A5BEFF4A7584E2
annotation: SIPB851531E8082E282
annotation: PRO_0000403609
annotation: SIP04E9954BBCE3386B
annotation: SIP30F5D16AE5A00396
annotation: SIP623FC89CDEC78EB7
annotation: SIPE7628269290B28AC
annotation: SIP8C6DCFF495D74F98
annotation: SIP549D42942E6BF40D
annotation: SIP0E7DC39766A45C02
annotation: SIPC7EDB3E656ACA081
annotation: SIP357157E11CC1F102
annotation: SIP4831C4CE9A3D9EAD
annotation: SIP95051D1A2203A4CD
annotation: SIP46EEDAE420A539AD
annotation: SIPE150FAAD29F39579
annotation: SIP399542B7B163F264
annotation: SIP793A7F6869379F48
annotation: SIPE55B5828260E30DE
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/235
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/269
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005739
classified with: GO_0005730
classified with: GO_0005654
classified with: GO_0005634
classified with: GO_0008409
classified with: GO_0017108
classified with: GO_0003677
classified with: GO_0000287
classified with: GO_0030145
classified with: GO_0004523
classified with: GO_0006284
classified with: GO_0043137
sequence: A9VB27-1
proteome: Unassembled WGS sequence

A9VB27-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2519
type: Resource
database: eggNOG
comment: Eukaryota

cd09867
type: Resource
database: CDD
comment: PIN_FEN1
signature sequence match: CDD cd09867 match 1

http://purl.uniprot.org/gene3d/1.10.150.20
type: Resource
database: Gene3D
comment: 5' to 3' exonuclease, C-terminal subdomain
signature sequence match: Gene3D 1.10.150.20 match 1

http://purl.uniprot.org/gene3d/3.40.50.1010
type: Resource
database: Gene3D
comment: 5'-nuclease
signature sequence match: Gene3D 3.40.50.1010 match 1

MF_00614
type: Resource
database: HAMAP
comment: Fen
signature sequence match: HAMAP MF 00614 match 1

IPR036279
type: Resource
database: InterPro
comment: 5-3_exonuclease_C_sf

IPR023426
type: Resource
database: InterPro
comment: Flap_endonuc

IPR008918
type: Resource
database: InterPro
comment: HhH2

IPR029060
type: Resource
database: InterPro
comment: PIN-like_dom_sf

IPR006086
type: Resource
database: InterPro
comment: XPG-I_dom

IPR006084
type: Resource
database: InterPro
comment: XPG/Rad2

IPR019974
type: Resource
database: InterPro
comment: XPG_CS

IPR006085
type: Resource
database: InterPro
comment: XPG_DNA_repair_N

PTHR11081:SF9
type: Resource
database: PANTHER
comment: FLAP ENDONUCLEASE 1
signature sequence match: PANTHER PTHR11081:SF9 match 1

PTHR11081
type: Resource
database: PANTHER
comment: FLAP ENDONUCLEASE FAMILY MEMBER
signature sequence match: PANTHER PTHR11081 match 1

PF00867
type: Resource
database: Pfam
comment: XPG_I
signature sequence match: Pfam PF00867 match 1

PF00752
type: Resource
database: Pfam
comment: XPG_N
signature sequence match: Pfam PF00752 match 1

PR00853
type: Resource
database: PRINTS
comment: XPGRADSUPER

SM00279
type: Resource
database: SMART
comment: HhH2
signature sequence match: SMART SM00279 match 1

SM00484
type: Resource
database: SMART
comment: XPGI
signature sequence match: SMART SM00484 match 1

SM00485
type: Resource
database: SMART
comment: XPGN
signature sequence match: SMART SM00485 match 1

SSF47807
type: Resource
database: SUPFAM
comment: 5' to 3' exonuclease, C-terminal subdomain
signature sequence match: SUPFAM SSF47807 match 1

SSF88723
type: Resource
database: SUPFAM
comment: PIN domain-like
signature sequence match: SUPFAM SSF88723 match 1

PS00841
type: Resource
database: PROSITE
comment: XPG_1
signature sequence match: PROSITE PS00841 match 1

PS00842
type: Resource
database: PROSITE
comment: XPG_2
signature sequence match: PROSITE PS00842 match 1

SIPD0F3B4537BEF6488
type: Structured Name
full name: Flap endonuclease 1
short name: FEN-1
ec name: 3.1.-.-

SIPD6CD844568711308
type: Structured Name
full name: Flap structure-specific endonuclease 1

FEN1
type: Gene
orf name: 29430

SIPA4EAD412BEB552B1
type: Function Annotation
comment: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

SIP1FA7150ABEF11412
type: Cofactor Annotation
comment: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
cofactor: CHEBI_18420

SIP4B3ED02016B8608C
type: Subunit Annotation
comment: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.

SIPC0EEBAB2CA08D3BD
type: Subcellular Location Annotation
comment: Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
located in: SIPCDA9A13819F90335
located in: SIP4DCB3647851242B8
located in: SIP2C0DEAC8C1E35A0D

SIP84A5BEFF4A7584E2
type: PTM Annotation
comment: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.

SIPB851531E8082E282
type: Similarity Annotation
comment: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.

PRO_0000403609
type: Chain Annotation
comment: Flap endonuclease 1
mass: 41441
range: 18358916126750510tt1tt368

18358916126750510tt1
type: Position
type: ExactPosition
position: 1
reference: A9VB27-1

18358916126750510tt368
type: Position
type: ExactPosition
position: 368
reference: A9VB27-1

SIP04E9954BBCE3386B
type: Region Annotation
comment: N-domain
range: 18358916126750510tt1tt104

18358916126750510tt104
type: Position
type: ExactPosition
position: 104
reference: A9VB27-1

SIP30F5D16AE5A00396
type: Region Annotation
comment: Disordered
range: 18358916126750510tt103tt123

18358916126750510tt103
type: Position
type: ExactPosition
position: 103
reference: A9VB27-1

18358916126750510tt123
type: Position
type: ExactPosition
position: 123
reference: A9VB27-1

SIP623FC89CDEC78EB7
type: Region Annotation
comment: I-domain
range: 18358916126750510tt122tt251

18358916126750510tt122
type: Position
type: ExactPosition
position: 122
reference: A9VB27-1

18358916126750510tt251
type: Position
type: ExactPosition
position: 251
reference: A9VB27-1

SIPE7628269290B28AC
type: Region Annotation
comment: Interaction with PCNA
range: 18358916126750510tt334tt342

18358916126750510tt334
type: Position
type: ExactPosition
position: 334
reference: A9VB27-1

18358916126750510tt342
type: Position
type: ExactPosition
position: 342
reference: A9VB27-1

18358916126750510tt34
type: Position
type: ExactPosition
position: 34
reference: A9VB27-1

18358916126750510tt47
type: Position
type: ExactPosition
position: 47
reference: A9VB27-1

18358916126750510tt70
type: Position
type: ExactPosition
position: 70
reference: A9VB27-1

18358916126750510tt86
type: Position
type: ExactPosition
position: 86
reference: A9VB27-1

18358916126750510tt158
type: Position
type: ExactPosition
position: 158
reference: A9VB27-1

18358916126750510tt160
type: Position
type: ExactPosition
position: 160
reference: A9VB27-1

18358916126750510tt179
type: Position
type: ExactPosition
position: 179
reference: A9VB27-1

18358916126750510tt181
type: Position
type: ExactPosition
position: 181
reference: A9VB27-1

18358916126750510tt229
type: Position
type: ExactPosition
position: 229
reference: A9VB27-1

18358916126750510tt231
type: Position
type: ExactPosition
position: 231
reference: A9VB27-1

1
subclass of: CHEBI_18420

2
subclass of: CHEBI_18420

A9VB27-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 41441
value: MGIHDLSKVIADKAPDAIKETEIKNLFDRKVAIDASMSIYQFLIAIRSEGSNLVNEAGEATSHLSGLFYRTIRMVNHGIKPLYVFDGKPPTMKSGELLKRGARRKEAQANLEEATEQGDTEQMEKFSRRLVHVTREHNEQCRQLLTLMGIPFIIAPTEAEAQCAELVKGGKVFATATEDMDALTFGTTVLLRHMTFSEARKMPIQEFRLQKGGLEMSMEEFIDMCILLGCDYCDSIKGIGRQKAYQLIKEHKNIETVLKHLDPKKYVIPEDWHFAEARELFLRPDVTPAAECEFKWTTPDIDGLVKFMCQENGFAEDRIRKSAEKLVKARKGGQQGRLDSFFTAIPSGSAKRNTVGLLPKPGPPPFLF

http://purl.uniprot.org/uniprot/A9VB27#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VB27#attribution-28C4C5067FDD2C7EC39F63B6297C2FDA
manual: true
evidence: ECO_0000255
source: MF_03140

A9UUB8
type: Protein
reviewed: true
created: 2008-07-01
modified: 2023-05-03
version: 55
mnemonic: FUCT1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPE2970672897B10DB
alternative name: SIP579CE97E977CBBF5
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPBE33416CC824ADBE
annotation: SIP6DA78C7167A461C8
annotation: SIP3E1EC0080F8F1229
annotation: SIP437C071D6DE8B127
annotation: PRO_0000343211
annotation: SIP48E689AB55A4254B
annotation: SIPEA28AFD4017099D9
annotation: SIP02D9A9F814E7BBCD
annotation: SIP17BD9240D27B413B
annotation: SIPFAEC785FC2662A21
annotation: SIP7DCF1048D359348A
annotation: SIPC888D9E95508D902
annotation: SIP51027134C2D4065A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/333
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/762
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005794
classified with: GO_0000139
classified with: GO_0015297
classified with: GO_0005457
classified with: GO_0008643
classified with: GO_0036085
classified with: GO_0036066
sequence: A9UUB8-1
proteome: Unassembled WGS sequence

A9UUB8-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1442
type: Resource
database: eggNOG
comment: Eukaryota

IPR004853
type: Resource
database: InterPro
comment: Sugar_P_trans_dom

PTHR11132:SF255
type: Resource
database: PANTHER
comment: GDP-FUCOSE TRANSPORTER 1
signature sequence match: PANTHER PTHR11132:SF255 match 1

PTHR11132
type: Resource
database: PANTHER
comment: SOLUTE CARRIER FAMILY 35
signature sequence match: PANTHER PTHR11132 match 1

PF03151
type: Resource
database: Pfam
comment: TPT
signature sequence match: Pfam PF03151 match 1

SIPE2970672897B10DB
type: Structured Name
full name: GDP-fucose transporter 1

SIP579CE97E977CBBF5
type: Structured Name
full name: Solute carrier family 35 member C1 homolog

slc35c1
type: Gene
alternative label: fuct1
orf name: 18313

SIPBE33416CC824ADBE
type: Function Annotation
comment: Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.

SIP437C071D6DE8B127
type: Similarity Annotation
comment: Belongs to the TPT transporter family. SLC35C subfamily.

PRO_0000343211
type: Chain Annotation
comment: GDP-fucose transporter 1
mass: 36727
range: 18358912151599150tt1tt333

18358912151599150tt1
type: Position
type: ExactPosition
position: 1
reference: A9UUB8-1

18358912151599150tt333
type: Position
type: ExactPosition
position: 333
reference: A9UUB8-1

SIP48E689AB55A4254B
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt13tt33

18358912151599150tt13
type: Position
type: ExactPosition
position: 13
reference: A9UUB8-1

18358912151599150tt33
type: Position
type: ExactPosition
position: 33
reference: A9UUB8-1

SIPEA28AFD4017099D9
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt45tt65

18358912151599150tt45
type: Position
type: ExactPosition
position: 45
reference: A9UUB8-1

18358912151599150tt65
type: Position
type: ExactPosition
position: 65
reference: A9UUB8-1

SIP02D9A9F814E7BBCD
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt95tt115

18358912151599150tt95
type: Position
type: ExactPosition
position: 95
reference: A9UUB8-1

18358912151599150tt115
type: Position
type: ExactPosition
position: 115
reference: A9UUB8-1

SIP17BD9240D27B413B
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt139tt159

18358912151599150tt139
type: Position
type: ExactPosition
position: 139
reference: A9UUB8-1

18358912151599150tt159
type: Position
type: ExactPosition
position: 159
reference: A9UUB8-1

SIPFAEC785FC2662A21
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt169tt189

18358912151599150tt169
type: Position
type: ExactPosition
position: 169
reference: A9UUB8-1

18358912151599150tt189
type: Position
type: ExactPosition
position: 189
reference: A9UUB8-1

SIP7DCF1048D359348A
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt211tt231

18358912151599150tt211
type: Position
type: ExactPosition
position: 211
reference: A9UUB8-1

18358912151599150tt231
type: Position
type: ExactPosition
position: 231
reference: A9UUB8-1

SIPC888D9E95508D902
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt239tt259

18358912151599150tt239
type: Position
type: ExactPosition
position: 239
reference: A9UUB8-1

18358912151599150tt259
type: Position
type: ExactPosition
position: 259
reference: A9UUB8-1

SIP51027134C2D4065A
type: Transmembrane Annotation
comment: Helical
range: 18358912151599150tt293tt313

18358912151599150tt293
type: Position
type: ExactPosition
position: 293
reference: A9UUB8-1

18358912151599150tt313
type: Position
type: ExactPosition
position: 313
reference: A9UUB8-1

A9UUB8-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 36727
value: MSPGQDATLLERSIKIAFVVALYWVVSISMVFLNKYLLSEVSLDAPMFVTWFQCVVAVVTCFILGELRSYHPALEMFPRFAFDTHVAMKVLPLSLVFVGMIAFNNLALKFVGVAFYNVGRSLTTIFNVLLSFFMLQQRTSMPALLMCGVIVAGFFVGVNKEQEQADLTMAGIMYGVLASLCVALNAIYIKKVMPFVDNDMWKLTAYNNMNAIFLFLPVITFMGEIPDIAASEDVYSGNYWFLMTVAGLLGIAIGLVSMLQINVTSPLTHNISGTSKACAQTILALQLNDESRTATWWLGNVFVLGGSLGYVLVKRAEMKRDLEKVPSSADSKA

http://purl.uniprot.org/uniprot/A9UUB8#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UUB8#attribution-68097C5C9D39FEEE8BE013645ACBBDD4
creator: UniProtKB
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UUB8#attribution-3F423AFE3BF7028F35A0FB424BCA7F5B
manual: true
evidence: ECO_0000250
source: Q96A29

http://purl.uniprot.org/uniprot/A9UUB8#attribution-62D85EBA0BD8C81241A43D6F9D4D4F70
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/A9UUB8#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9US33
type: Protein
reviewed: true
created: 2011-05-31
modified: 2023-06-28
version: 35
mnemonic: GHL3_MONBE
citation: http://purl.uniprot.org/citations/18273011
citation: http://purl.uniprot.org/citations/20556855
recommended name: SIPEEBA9CF64C2D71FD
enzyme: http://purl.uniprot.org/enzyme/3.2.1.-
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP4E86CE0AE33E285A
annotation: PRO_0000408873
annotation: SIPEE95D79A3B4F5791
annotation: SIP27E31D1F0BC087FB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/326
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0016798
classified with: GO_0008152
sequence: A9US33-1
proteome: Unassembled WGS sequence

A9US33-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

A9US33-citation-20556855
type: Citation Statement
scope: PUTATIVE FUNCTION
scope: FAMILY ASSIGNMENT

ENOG502SHKS
type: Resource
database: eggNOG
comment: Eukaryota

IPR046226
type: Resource
database: InterPro
comment: DUF6259

PF19773
type: Resource
database: Pfam
comment: DUF6259
signature sequence match: Pfam PF19773 match 1

SIPEEBA9CF64C2D71FD
type: Structured Name
full name: Putative glycoside hydrolase 22789
ec name: 3.2.1.-

http://purl.uniprot.org/uniprot/A9US33#gene-MD54312A1AB8592043844EDDC61A2306DAB
type: Gene
orf name: 22789

SIP4E86CE0AE33E285A
type: Similarity Annotation
comment: Belongs to the glycoside hydrolase-like 3 (GHL3) family.

PRO_0000408873
type: Chain Annotation
comment: Putative glycoside hydrolase 22789
mass: 129012
range: 18358912117060398tt1tt1191

18358912117060398tt1
type: Position
type: ExactPosition
position: 1
reference: A9US33-1

18358912117060398tt1191
type: Position
type: ExactPosition
position: 1191
reference: A9US33-1

SIPEE95D79A3B4F5791
type: Region Annotation
comment: Disordered
range: 18358912117060398tt173tt221

18358912117060398tt173
type: Position
type: ExactPosition
position: 173
reference: A9US33-1

18358912117060398tt221
type: Position
type: ExactPosition
position: 221
reference: A9US33-1

SIP27E31D1F0BC087FB
type: Compositional Bias Annotation
comment: Polar residues
range: 18358912117060398tt173tt191

18358912117060398tt191
type: Position
type: ExactPosition
position: 191
reference: A9US33-1

A9US33-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 129012
value: MDPNNAAASSAHDLSSLDLSCLNEAERIVINSFMRGPHAHFEHLGVGPNVKWDENLSKRAFYHLVAINHATLKLLVAQARLCSMQQMNAPNLTNGASATALGSLHPFSLGNPATSVTMASNPLANGPGLRTQLMAPDFALALLGNGTTPHASAGLGALNPGLYNPSASILGGPSSSGASSVLPSPSAHTPDAATDANHLPNPDPASGRQELTRAGRPARKKMKATALDAALRTEMPNWPSVQDDFVRWTRLAWFEAGFASTISDGAIGVQTRRPFSPFLTTTFAQVGVHLPSMSPNLLRAFNSWVDMHLRSLRDHFKGRIDKPHAGKASLAARSLEDTTFVSLTEFINNMCNSYNLINSELSVAAVRALCKLYLNVRNMATAKDSEGVLRVHIRDASNRQPPNILRGTLPQDREDDDLLTLITECGAIDFDLPTDTSDTMALAVLMVMSTSATTLTLDQAGCFSSLSGAASAQVNLLTNVTCEWFSVTMVTESGTSTISLPSSTRPSAHISAHGKDFALSWPKITEGLEIDIGLTLELQHNVTLDAYELRAKVVNHRPKAKASLWQLELNLRNVRQPEDGSAFFPAGYGVRYQGAFAASGSYPSSGATMQWMAAGGGAANEGQGLYLAAHDGYGYIKFLNAAAVEDVASLSIVYLVEDAGLPFAESTMPFPLTLAVVGGGDDLWYQAAQMYRTFALGEAQWMQAGRLHQRQDIPGWYVNNSIWINSGWQCHDIFNETQGDPHTVLNVTRRIRERFNTNMALHWYEWQQGPDANASARYRFDTHYPDYLPPRGGDYFGTVVRELEKEGVHIFPYINGRIFDVASTSYAQHNGSDHCCRKANPSFGAADQSFYVESYGSGSTFHTADPTDIYWQTTLADTVDALVNTYGVEGVYIDQLAAAAPTPDWTSWHNHTKGGGFYWRTGIVDIIKAMRQRVGPTVPLVTESNSEPYMDAISGFLTLVAFEPAFVGTKALVPAFPAIYGGYFVGFGDIFNAEDLADQDPLMARVVAQFVYGAQLGWFSLGGVTSGPDVDTSCGKMGEYDLWMSESSDAIVAAVEYYGNLRVCLLEYLAHGRILAPPSLSPAPAEFMAVETAVQNAGPFPSAMSAVWLHEDEASAVIIVAGVLDAGQTYNVSVDLTFSLPSLHDRQVTVQEMSCDGLSQQLDVMPANDIQIYDVTLSDRNARVYRVHFGA

http://purl.uniprot.org/uniprot/A9US33#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9VE54
type: Protein
reviewed: true
created: 2011-10-19
modified: 2023-09-13
version: 66
mnemonic: ITPA_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPD8C5AFC7A6CA5E70
alternative name: SIP5FCC919668B8EABF
alternative name: SIP07CA757074EFFA74
alternative name: SIP603A72734A4B9793
alternative name: SIP0CA6CE7AD3F5EB85
enzyme: http://purl.uniprot.org/enzyme/3.6.1.9
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP7799AEE118EF15C6
annotation: SIP3D78AEEA7DD8AD4A
annotation: SIP87D320E9FE614792
annotation: SIP082B8132D4C482A5
annotation: SIPF3C041FED19C53B9
annotation: SIP8D99C60805E36479
annotation: SIP6AA98FCE4EA52E24
annotation: SIPD5F2D71D60B6E620
annotation: SIPB8028F3FFB0DCA21
annotation: SIP12CFF2A5D411ED61
annotation: PRO_0000413154
annotation: SIP9524C52228728A44
annotation: SIPBB5C702A1BF61006
annotation: SIP68B94A18B74B118D
annotation: SIP8A50103AC03D9B4A
annotation: SIPB4612CEDE8C0D6D8
annotation: SIP6957554D1F9CDFCD
annotation: SIP8B1CC64BB3408360
annotation: SIP09C24C981467B2F4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/546
classified with: http://purl.uniprot.org/keywords/547
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0035870
classified with: GO_0036220
classified with: GO_0046872
classified with: GO_0047429
classified with: GO_0000166
classified with: GO_0036222
classified with: GO_0009204
classified with: GO_0009143
classified with: GO_0009117
sequence: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA
proteome: Unassembled WGS sequence

A9VE54-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3222
type: Resource
database: eggNOG
comment: Eukaryota

cd00515
type: Resource
database: CDD
comment: HAM1
signature sequence match: CDD cd00515 match 1

MF_03148
type: Resource
database: HAMAP
comment: HAM1_NTPase
signature sequence match: HAMAP MF 03148 match 1

IPR027502
type: Resource
database: InterPro
comment: ITPase

IPR029001
type: Resource
database: InterPro
comment: ITPase-like_fam

IPR002637
type: Resource
database: InterPro
comment: RdgB/HAM1

PTHR11067:SF9
type: Resource
database: PANTHER
comment: INOSINE TRIPHOSPHATE PYROPHOSPHATASE
signature sequence match: PANTHER PTHR11067:SF9 match 1

PTHR11067
type: Resource
database: PANTHER
comment: INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN
signature sequence match: PANTHER PTHR11067 match 1

PF01725
type: Resource
database: Pfam
comment: Ham1p_like
signature sequence match: Pfam PF01725 match 1

SSF52972
type: Resource
database: SUPFAM
comment: ITPase-like
signature sequence match: SUPFAM SSF52972 match 1

SIPD8C5AFC7A6CA5E70
type: Structured Name
full name: Inosine triphosphate pyrophosphatase
short name: ITPase
short name: Inosine triphosphatase
ec name: 3.6.1.9

SIP5FCC919668B8EABF
type: Structured Name
full name: Non-canonical purine NTP pyrophosphatase

SIP07CA757074EFFA74
type: Structured Name
full name: Non-standard purine NTP pyrophosphatase

SIP603A72734A4B9793
type: Structured Name
full name: Nucleoside-triphosphate diphosphatase

SIP0CA6CE7AD3F5EB85
type: Structured Name
full name: Nucleoside-triphosphate pyrophosphatase
short name: NTPase

http://purl.uniprot.org/uniprot/A9VE54#gene-MD57739F5D6B21198AF8FFAA4619C38A29C
type: Gene
orf name: 13033

SIP7799AEE118EF15C6
type: Function Annotation
comment: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

SIP6AA98FCE4EA52E24
type: Cofactor Annotation
comment: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
cofactor: CHEBI_18420
cofactor: CHEBI_29035

SIPD5F2D71D60B6E620
type: Subunit Annotation
comment: Homodimer.

SIP12CFF2A5D411ED61
type: Similarity Annotation
comment: Belongs to the HAM1 NTPase family.

PRO_0000413154
type: Chain Annotation
comment: Inosine triphosphate pyrophosphatase
mass: 21842
range: 18358916177277998tt1tt199

18358916177277998tt1
type: Position
type: ExactPosition
position: 1
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt199
type: Position
type: ExactPosition
position: 199
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt12
type: Position
type: ExactPosition
position: 12
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt17
type: Position
type: ExactPosition
position: 17
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt42
type: Position
type: ExactPosition
position: 42
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt54
type: Position
type: ExactPosition
position: 54
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt70
type: Position
type: ExactPosition
position: 70
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt71
type: Position
type: ExactPosition
position: 71
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt87
type: Position
type: ExactPosition
position: 87
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt146
type: Position
type: ExactPosition
position: 146
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt149
type: Position
type: ExactPosition
position: 149
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt169
type: Position
type: ExactPosition
position: 169
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt174
type: Position
type: ExactPosition
position: 174
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

18358916177277998tt175
type: Position
type: ExactPosition
position: 175
reference: MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA

MAKTTAAITFVTGNAKKLQEVQQILGQGFPFELTNRKIDLPELQGEPEDISREKCRLAAAEVKGPVMVEDTSLCFNALHGLPGPYIKWFLDKTGHVGLNNLLAAYPDKSAYAQCIFAFTTGPGAEIQTFVGRTEGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKTIKNSISHRGRSLSALCAYFDTHKAELEKQLAA
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 21842

http://purl.uniprot.org/uniprot/A9VE54#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VE54#attribution-90D6E0BE39F24D99860F925B0936EA1C
manual: true
evidence: ECO_0000255
source: MF_03148

A9V3C0
type: Protein
reviewed: true
created: 2009-01-20
modified: 2023-09-13
version: 77
mnemonic: KYNU_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP9D65C7BA5834574E
alternative name: SIPF4476F51DB126AA4
enzyme: http://purl.uniprot.org/enzyme/3.7.1.3
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP3090C068C27C53DE
annotation: SIP9A137A6DB58922C7
annotation: SIP49FD12177D7A1EE8
annotation: SIPA6A753ED32B0217F
annotation: SIP0EBDCE1E2F9AB596
annotation: SIP208495C5D11D83D3
annotation: SIP235970821CCBF2D0
annotation: SIP382C0B2EAF994B6D
annotation: SIP098C1DF2D175DDF5
annotation: PRO_0000361087
annotation: SIP742C117A2D6D36D3
annotation: SIP91FFEF3A661A0FE7
annotation: SIP0C330CCC2D99EB0A
annotation: SIPB90A2DC99BD36011
annotation: SIPF0CBF69FD6DEB8A8
annotation: SIP79FA090A4E6EA2B6
annotation: SIPC187EF8A51C57F59
annotation: SIP49320D982390394F
annotation: SIPD35891A8A9A258B7
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/378
classified with: http://purl.uniprot.org/keywords/662
classified with: http://purl.uniprot.org/keywords/663
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0061981
classified with: GO_0030429
classified with: GO_0030170
classified with: GO_0034354
classified with: GO_0043420
classified with: GO_0097053
classified with: GO_0019805
classified with: GO_0019441
sequence: A9V3C0-1
proteome: Unassembled WGS sequence

A9V3C0-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3846
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.90.1150.10
type: Resource
database: Gene3D
comment: Aspartate Aminotransferase, domain 1
signature sequence match: Gene3D 3.90.1150.10 match 1

http://purl.uniprot.org/gene3d/3.40.640.10
type: Resource
database: Gene3D
comment: Type I PLP-dependent aspartate aminotransferase-like (Major domain)
signature sequence match: Gene3D 3.40.640.10 match 1

MF_01970
type: Resource
database: HAMAP
comment: Kynureninase
signature sequence match: HAMAP MF 01970 match 1

IPR000192
type: Resource
database: InterPro
comment: Aminotrans_V_dom

IPR010111
type: Resource
database: InterPro
comment: Kynureninase

IPR015424
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase

IPR015421
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_major

IPR015422
type: Resource
database: InterPro
comment: PyrdxlP-dep_Trfase_small

TIGR01814
type: Resource
database: NCBIfam
comment: kynureninase
signature sequence match: NCBIfam TIGR01814 match 1

PTHR14084
type: Resource
database: PANTHER
comment: KYNURENINASE
signature sequence match: PANTHER PTHR14084 match 1

PTHR14084:SF0
type: Resource
database: PANTHER
comment: KYNURENINASE
signature sequence match: PANTHER PTHR14084:SF0 match 1

PF00266
type: Resource
database: Pfam
comment: Aminotran_5
signature sequence match: Pfam PF00266 match 1

PIRSF038800
type: Resource
database: PIRSF
comment: KYNU
signature sequence match: PIRSF PIRSF038800 match 1

SSF53383
type: Resource
database: SUPFAM
comment: PLP-dependent transferases
signature sequence match: SUPFAM SSF53383 match 1

SIP9D65C7BA5834574E
type: Structured Name
full name: Kynureninase
ec name: 3.7.1.3

SIPF4476F51DB126AA4
type: Structured Name
full name: L-kynurenine hydrolase

kynu
type: Gene
orf name: 26773

SIP3090C068C27C53DE
type: Function Annotation
comment: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

SIP235970821CCBF2D0
type: Subunit Annotation
comment: Homodimer.

SIP098C1DF2D175DDF5
type: Similarity Annotation
comment: Belongs to the kynureninase family.

PRO_0000361087
type: Chain Annotation
comment: Kynureninase
mass: 51259
range: 18358915876204590tt1tt460

18358915876204590tt1
type: Position
type: ExactPosition
position: 1
reference: A9V3C0-1

18358915876204590tt460
type: Position
type: ExactPosition
position: 460
reference: A9V3C0-1

18358915876204590tt127
type: Position
type: ExactPosition
position: 127
reference: A9V3C0-1

18358915876204590tt128
type: Position
type: ExactPosition
position: 128
reference: A9V3C0-1

18358915876204590tt165
type: Position
type: ExactPosition
position: 165
reference: A9V3C0-1

18358915876204590tt168
type: Position
type: ExactPosition
position: 168
reference: A9V3C0-1

18358915876204590tt249
type: Position
type: ExactPosition
position: 249
reference: A9V3C0-1

18358915876204590tt252
type: Position
type: ExactPosition
position: 252
reference: A9V3C0-1

18358915876204590tt274
type: Position
type: ExactPosition
position: 274
reference: A9V3C0-1

18358915876204590tt304
type: Position
type: ExactPosition
position: 304
reference: A9V3C0-1

18358915876204590tt332
type: Position
type: ExactPosition
position: 332
reference: A9V3C0-1

SIPD35891A8A9A258B7
type: Modified Residue Annotation
comment: N6-(pyridoxal phosphate)lysine
range: 18358915876204590tt275tt275

18358915876204590tt275
type: Position
type: ExactPosition
position: 275
reference: A9V3C0-1

A9V3C0-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 51259
value: MHLARELGVNLADQRLAQALDEADPLAHLRQEFSIPQMKDIKQADLKLVEAESDCIYLCGNSLGLMPKRTRTIVNEELDTWATGGVTGHFPDGPGKRPWVSIDETVTDKCARVVGALPEEVAIMNTLTVNLHLLMVSLAHTMARQVPFYRPTSDRFKILVEAKAFPSDHFAVLSQLRMHGHDESALIEVKPREGEHNIREEDLLAILEEQGDSIATVLVGGVHYYTGQFFDLQRLCAAAHNKGCTFGVDLAHAVGNVPLQLHDWDIDFACWCTYKYLNSGPGGIAGAFIHKKHEGTSRPYLQGWWGVQLNERFRMDHDASFMPGVRGLQLSNPGVLQTVALLGSLEIYEQTDMASLRAKSLKLTAYLEQLMQALVNEEGHAPRFEIITPTDPERRGCQLSILFKVDIDAAFEALEKRGVVCDVRRPDVMRIAPVPLYNTFTDVYRFVTTLRDALNASASS

http://purl.uniprot.org/uniprot/A9V3C0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V3C0#attribution-730B651F8CA41CD89C6FBBD2C8BA723C
manual: true
evidence: ECO_0000255
source: MF_03017

A9V790
type: Protein
reviewed: true
created: 2011-02-08
modified: 2023-05-03
version: 79
mnemonic: LIS1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP02F7DB69D4BEBB4C
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP6E1D8401AC605242
annotation: SIP092ED29269E765E3
annotation: SIP69D7FF69AF5E65EF
annotation: SIPD6E36ACF448F3C4E
annotation: PRO_0000405115
annotation: SIPE0F049F8714CCFBB
annotation: SIP1F958502293EA011
annotation: SIP8E67A00A192A5629
annotation: SIP0A29D9FD2AC90C6A
annotation: SIP1FAF777742200602
annotation: SIP467CFB59A1C0F5DB
annotation: SIP6E78A8722D9F13EA
annotation: SIP442A38CE89A64637
annotation: SIP71A972D05938E2C2
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/175
classified with: http://purl.uniprot.org/keywords/206
classified with: http://purl.uniprot.org/keywords/493
classified with: http://purl.uniprot.org/keywords/498
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/813
classified with: http://purl.uniprot.org/keywords/853
classified with: GO_0005881
classified with: GO_0000776
classified with: GO_0005875
classified with: GO_0005815
classified with: GO_0005635
classified with: GO_0070840
classified with: GO_0051010
classified with: GO_0051301
classified with: GO_0000132
classified with: GO_0031023
classified with: GO_0051012
classified with: GO_0007097
classified with: GO_0047496
sequence: A9V790-1
proteome: Unassembled WGS sequence

A9V790-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0295
type: Resource
database: eggNOG
comment: Eukaryota

MF_03141
type: Resource
database: HAMAP
comment: lis1
signature sequence match: HAMAP MF 03141 match 1

IPR017252
type: Resource
database: InterPro
comment: Dynein_regulator_LIS1

IPR020472
type: Resource
database: InterPro
comment: G-protein_beta_WD-40_rep

IPR037190
type: Resource
database: InterPro
comment: LIS1_N

IPR006594
type: Resource
database: InterPro
comment: LisH

PTHR19879
type: Resource
database: PANTHER
comment: TRANSCRIPTION INITIATION FACTOR TFIID
signature sequence match: PANTHER PTHR19879 match 1

PTHR19879:SF9
type: Resource
database: PANTHER
comment: WD_REPEATS_REGION DOMAIN-CONTAINING PROTEIN
signature sequence match: PANTHER PTHR19879:SF9 match 1

PIRSF037647
type: Resource
database: PIRSF
comment: Dynein_regulator_Lis1
signature sequence match: PIRSF PIRSF037647 match 1

PR00320
type: Resource
database: PRINTS
comment: GPROTEINBRPT

SSF109925
type: Resource
database: SUPFAM
comment: Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
signature sequence match: SUPFAM SSF109925 match 1

PS50896
type: Resource
database: PROSITE
comment: LISH
signature sequence match: PROSITE PS50896 match 1

SIP02F7DB69D4BEBB4C
type: Structured Name
full name: Lissencephaly-1 homolog

http://purl.uniprot.org/uniprot/A9V790#gene-MD54913DB07FB426CF2F59E655776BE4B9D
type: Gene
orf name: 35260

SIP6E1D8401AC605242
type: Function Annotation
comment: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.

SIP092ED29269E765E3
type: Subcellular Location Annotation
comment: Localizes to the plus end of microtubules and to the centrosome.
located in: SIP1B9C834CC1092B9D
located in: SIP380472F0B4F48079

SIP69D7FF69AF5E65EF
type: Domain Annotation
comment: Dimerization mediated by the LisH domain may be required to activate dynein.

SIPD6E36ACF448F3C4E
type: Similarity Annotation
comment: Belongs to the WD repeat LIS1/nudF family.

PRO_0000405115
type: Chain Annotation
comment: Lissencephaly-1 homolog
mass: 45189
range: 18358915942658094tt1tt410

18358915942658094tt1
type: Position
type: ExactPosition
position: 1
reference: A9V790-1

18358915942658094tt410
type: Position
type: ExactPosition
position: 410
reference: A9V790-1

SIPE0F049F8714CCFBB
type: Domain Extent Annotation
comment: LisH
range: 18358915942658094tt7tt39

18358915942658094tt7
type: Position
type: ExactPosition
position: 7
reference: A9V790-1

18358915942658094tt39
type: Position
type: ExactPosition
position: 39
reference: A9V790-1

SIP1F958502293EA011
type: Repeat Annotation
comment: WD 1
range: 18358915942658094tt104tt143

18358915942658094tt104
type: Position
type: ExactPosition
position: 104
reference: A9V790-1

18358915942658094tt143
type: Position
type: ExactPosition
position: 143
reference: A9V790-1

SIP8E67A00A192A5629
type: Repeat Annotation
comment: WD 2
range: 18358915942658094tt146tt185

18358915942658094tt146
type: Position
type: ExactPosition
position: 146
reference: A9V790-1

18358915942658094tt185
type: Position
type: ExactPosition
position: 185
reference: A9V790-1

SIP0A29D9FD2AC90C6A
type: Repeat Annotation
comment: WD 3
range: 18358915942658094tt188tt227

18358915942658094tt188
type: Position
type: ExactPosition
position: 188
reference: A9V790-1

18358915942658094tt227
type: Position
type: ExactPosition
position: 227
reference: A9V790-1

SIP1FAF777742200602
type: Repeat Annotation
comment: WD 4
range: 18358915942658094tt230tt269

18358915942658094tt230
type: Position
type: ExactPosition
position: 230
reference: A9V790-1

18358915942658094tt269
type: Position
type: ExactPosition
position: 269
reference: A9V790-1

SIP467CFB59A1C0F5DB
type: Repeat Annotation
comment: WD 5
range: 18358915942658094tt294tt333

18358915942658094tt294
type: Position
type: ExactPosition
position: 294
reference: A9V790-1

18358915942658094tt333
type: Position
type: ExactPosition
position: 333
reference: A9V790-1

SIP6E78A8722D9F13EA
type: Repeat Annotation
comment: WD 6
range: 18358915942658094tt336tt375

18358915942658094tt336
type: Position
type: ExactPosition
position: 336
reference: A9V790-1

18358915942658094tt375
type: Position
type: ExactPosition
position: 375
reference: A9V790-1

SIP442A38CE89A64637
type: Repeat Annotation
comment: WD 7
range: 18358915942658094tt378tt410

18358915942658094tt378
type: Position
type: ExactPosition
position: 378
reference: A9V790-1

18358915942658094tt55
type: Position
type: ExactPosition
position: 55
reference: A9V790-1

18358915942658094tt80
type: Position
type: ExactPosition
position: 80
reference: A9V790-1

A9V790-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 45189
value: MVLTARQQEELQLAVHAYLVEAGHAEAAAAMAKSANLGDDAGDAKYTGLLEKKWTTITRLQKRNMELQAEVEELRSSARAPRSRTTTKMEEWVPRPPATVAVDGHRLPITAVAIHPSFAVMASASEDASIKLWDMESGNFERSLKGHTNAVNDIAYDREGNRLVSCSTDMTIKVWNMDNFTCTKTLSGHDHTVSSVRFDHTGDRVFSASRDKTIKIWELATGYCLQTLQGHSDWVRSIDVSADGAWICSASSDHTVRVWSVASGECKHVWSDHEHVVEHASFAPLVAHEALNLMIFGSKPSAEAASKGPFVASASRDKSICLFDVSTGQHLARLTGHDNWVRATAWSRGGRYLFSVADDKTMRVWDIATKRVSKTIPAHNHFVSCIAVHAKNTHVVTGSVDLKVKVWECN

http://purl.uniprot.org/uniprot/A9V790#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V790#attribution-8ADEC7FC9408C9D46A8A02228303D1F7
manual: true
evidence: ECO_0000255
source: MF_03141

A9UQ62
type: Protein
reviewed: true
created: 2010-11-30
modified: 2023-09-13
version: 64
mnemonic: MTNA_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPA1E30308C22C4FDA
alternative name: SIPEB12C938C49896CE
alternative name: SIP2FE3549F3E4FA470
enzyme: http://purl.uniprot.org/enzyme/5.3.1.23
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP19B56FC9E52D1562
annotation: SIP12A297D91A005907
annotation: SIPEFE5AC61902892AF
annotation: SIP74628C43617BA8DA
annotation: SIP5BD56761384C6494
annotation: PRO_0000402061
annotation: SIP234966B1F8BB2B3C
annotation: SIPD19A2966E8704BCB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/413
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005634
classified with: GO_0046523
classified with: GO_0019509
classified with: GO_0019284
sequence: A9UQ62-1
proteome: Unassembled WGS sequence

A9UQ62-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1468
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/1.20.120.420
type: Resource
database: Gene3D
comment: translation initiation factor eif-2b, domain 1
signature sequence match: Gene3D 1.20.120.420 match 1

MF_01678
type: Resource
database: HAMAP
comment: Salvage_MtnA
signature sequence match: HAMAP MF 01678 match 1

IPR000649
type: Resource
database: InterPro
comment: IF-2B-related

IPR005251
type: Resource
database: InterPro
comment: IF-M1Pi

IPR042529
type: Resource
database: InterPro
comment: IF_2B-like_C

IPR011559
type: Resource
database: InterPro
comment: Initiation_fac_2B_a/b/d

IPR027363
type: Resource
database: InterPro
comment: M1Pi_N

IPR037171
type: Resource
database: InterPro
comment: NagB/RpiA_transferase-like

TIGR00524
type: Resource
database: NCBIfam
comment: eIF-2B_rel
signature sequence match: NCBIfam TIGR00524 match 1

TIGR00512
type: Resource
database: NCBIfam
comment: salvage_mtnA
signature sequence match: NCBIfam TIGR00512 match 1

PTHR43475
type: Resource
database: PANTHER
comment: METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE
signature sequence match: PANTHER PTHR43475 match 1

PTHR43475:SF1
type: Resource
database: PANTHER
comment: METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE
signature sequence match: PANTHER PTHR43475:SF1 match 1

PF01008
type: Resource
database: Pfam
comment: IF-2B
signature sequence match: Pfam PF01008 match 1

SSF100950
type: Resource
database: SUPFAM
comment: NagB/RpiA/CoA transferase-like
signature sequence match: SUPFAM SSF100950 match 1

SIPA1E30308C22C4FDA
type: Structured Name
full name: Methylthioribose-1-phosphate isomerase
short name: M1Pi
short name: MTR-1-P isomerase
ec name: 5.3.1.23

SIPEB12C938C49896CE
type: Structured Name
full name: S-methyl-5-thioribose-1-phosphate isomerase

SIP2FE3549F3E4FA470
type: Structured Name
full name: Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein

http://purl.uniprot.org/uniprot/A9UQ62#gene-MD5DC3A6B5D6D879491B1B11FD82C148395
type: Gene
orf name: 34861

SIP19B56FC9E52D1562
type: Function Annotation
comment: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

SIP5BD56761384C6494
type: Similarity Annotation
comment: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

PRO_0000402061
type: Chain Annotation
comment: Methylthioribose-1-phosphate isomerase
mass: 38755
range: 18358912083702318tt1tt361

18358912083702318tt1
type: Position
type: ExactPosition
position: 1
reference: A9UQ62-1

18358912083702318tt361
type: Position
type: ExactPosition
position: 361
reference: A9UQ62-1

SIP234966B1F8BB2B3C
type: Active Site Annotation
comment: Proton donor
range: 18358912083702318tt245tt245

18358912083702318tt245
type: Position
type: ExactPosition
position: 245
reference: A9UQ62-1

SIPD19A2966E8704BCB
type: Site Annotation
comment: Transition state stabilizer
range: 18358912083702318tt165tt165

18358912083702318tt165
type: Position
type: ExactPosition
position: 165
reference: A9UQ62-1

A9UQ62-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 38755
value: MATLEAIKYDGEKLLVLDQIKLPLETHYDEVLSIQDGWDAIREMRVRGAPAIAIVAALTIAVVMKRSTFATAAELAAFVRTSLEHLRTSRPTAVNLFEMAGRLEALLQEQPADCTEAALRQAVLSYIEGMMQADIADNQAIGKFGAEAILKDLSADVKVKVLTHCNTGSLATARYGTALGVIRSLHEQQRLEHAFCTETRPYNQGARLTAYELVTEGIPGTLVADSMVSLLMKQKGISAVVVGADRVVANGDTANKIGTYQIAIAAKHHGVPFFVAAPLTSVDLKLSHGSEITIEERPGKELTHIFGQQLAAPGIGTWNPAFDVTPADLITGIITERGVAYKAEGQQEFDMASFAASVGRA

http://purl.uniprot.org/uniprot/A9UQ62#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UQ62#attribution-F02D2FE1BC9296A13609C5E835BC6EA1
manual: true
evidence: ECO_0000255
source: MF_03119

A9VCQ2
type: Protein
reviewed: true
created: 2010-04-20
modified: 2023-09-13
version: 64
mnemonic: MTNB_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP51BC693D3F620CAE
enzyme: http://purl.uniprot.org/enzyme/4.2.1.109
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPA2AA55732F3D4898
annotation: SIP52EEC922D7C41E4D
annotation: SIP2020B2DD453AFD28
annotation: SIP0D1BDE94F50AD7F4
annotation: SIP23E2D5C19D9585F0
annotation: SIP2F8121D3CDAD8334
annotation: PRO_0000393858
annotation: SIP03CAA4F7B3939B28
annotation: SIP97B376E5955665B7
annotation: SIP85B68C130845E0EF
annotation: SIP9C2F5383DCB2FBE1
annotation: SIP2C69424EC1AF813A
annotation: SIPB073BCBC04DC7C5A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005737
classified with: GO_0046570
classified with: GO_0008270
classified with: GO_0019509
classified with: GO_0019284
sequence: A9VCQ2-1
proteome: Unassembled WGS sequence

A9VCQ2-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2631
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.40.225.10
type: Resource
database: Gene3D
comment: Class II aldolase/adducin N-terminal domain
signature sequence match: Gene3D 3.40.225.10 match 1

MF_03116
type: Resource
database: HAMAP
comment: Salvage_MtnB_euk
signature sequence match: HAMAP MF 03116 match 1

IPR001303
type: Resource
database: InterPro
comment: Aldolase_II/adducin_N

IPR036409
type: Resource
database: InterPro
comment: Aldolase_II/adducin_N_sf

IPR017714
type: Resource
database: InterPro
comment: MethylthioRu-1-P_deHdtase_MtnB

IPR027514
type: Resource
database: InterPro
comment: Salvage_MtnB_euk

TIGR03328
type: Resource
database: NCBIfam
comment: salvage_mtnB
signature sequence match: NCBIfam TIGR03328 match 1

PTHR10640
type: Resource
database: PANTHER
comment: METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE
signature sequence match: PANTHER PTHR10640 match 1

PTHR10640:SF7
type: Resource
database: PANTHER
comment: METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE
signature sequence match: PANTHER PTHR10640:SF7 match 1

PF00596
type: Resource
database: Pfam
comment: Aldolase_II
signature sequence match: Pfam PF00596 match 1

SM01007
type: Resource
database: SMART
comment: Aldolase_II
signature sequence match: SMART SM01007 match 1

SSF53639
type: Resource
database: SUPFAM
comment: AraD/HMP-PK domain-like
signature sequence match: SUPFAM SSF53639 match 1

SIP51BC693D3F620CAE
type: Structured Name
full name: Probable methylthioribulose-1-phosphate dehydratase
short name: MTRu-1-P dehydratase
ec name: 4.2.1.109

http://purl.uniprot.org/uniprot/A9VCQ2#gene-MD5170370FBEC52570B109EE284FBBC1561
type: Gene
orf name: 29994

SIPA2AA55732F3D4898
type: Function Annotation
comment: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

SIP2020B2DD453AFD28
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP2F8121D3CDAD8334
type: Similarity Annotation
comment: Belongs to the aldolase class II family. MtnB subfamily.

PRO_0000393858
type: Chain Annotation
comment: Probable methylthioribulose-1-phosphate dehydratase
mass: 27870
range: 18358916145558062tt1tt249

18358916145558062tt1
type: Position
type: ExactPosition
position: 1
reference: A9VCQ2-1

18358916145558062tt249
type: Position
type: ExactPosition
position: 249
reference: A9VCQ2-1

SIP03CAA4F7B3939B28
type: Region Annotation
comment: Disordered
range: 18358916145558062tt230tt249

18358916145558062tt230
type: Position
type: ExactPosition
position: 230
reference: A9VCQ2-1

SIP97B376E5955665B7
type: Active Site Annotation
comment: Proton donor/acceptor
range: 18358916145558062tt136tt136

18358916145558062tt136
type: Position
type: ExactPosition
position: 136
reference: A9VCQ2-1

18358916145558062tt95
type: Position
type: ExactPosition
position: 95
reference: A9VCQ2-1

18358916145558062tt113
type: Position
type: ExactPosition
position: 113
reference: A9VCQ2-1

18358916145558062tt115
type: Position
type: ExactPosition
position: 115
reference: A9VCQ2-1

18358916145558062tt192
type: Position
type: ExactPosition
position: 192
reference: A9VCQ2-1

substrate

A9VCQ2-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 27870
value: MAAEPAALSARYFDDRYGPEHPRNLIPELCRLFYRNGWVTGTGGGISIKHEGKIYIAPSGVQKERIEPADFFVTDEAGTVLETPPADKMLKMSECTPLFMNAFTMRKAGACLHSHSPNAVLATMLCDKELRITNIEMIKGIRKASTGQSYGYYDTLVIPIIENTAREAELQSRMAACMEEYPDTCAVLVRRHGVYVWGDTWQKAKGMVECYDYLFEMFIRMKQLGLDPEQPDVNGAARAAEPDAKKAKQ

http://purl.uniprot.org/uniprot/A9VCQ2#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VCQ2#attribution-29BBB8CB29A6B5DABC594509798AD444
manual: true
evidence: ECO_0000255
source: MF_03116

A9VCM7
type: Protein
reviewed: true
created: 2011-12-14
modified: 2023-05-03
version: 70
mnemonic: MTND_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP6C4F507236151752
alternative name: SIPC0D160E1090886D0
alternative name: SIPC9EB0D8DEB78CD5E
enzyme: http://purl.uniprot.org/enzyme/1.13.11.54
enzyme: http://purl.uniprot.org/enzyme/1.13.11.53
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPF8F17208FC72F26C
annotation: SIP91CC23458EE20B63
annotation: SIP28153168EB4AB0A2
annotation: SIP231B8905F4C5321E
annotation: SIPAE664C9D92F70D32
annotation: SIPB54C7221B6FCBA98
annotation: SIP416FDE7A2D2C4378
annotation: PRO_0000414340
annotation: SIP46E98CED0DBDA1EA
annotation: SIP0AEFF0C3213CA737
annotation: SIPBB609724D29AEFD4
annotation: SIP9D20807410CD3B2F
annotation: SIPA40CD33C06BD2658
annotation: SIP63CABDC66607444B
annotation: SIPBD2880576EF57D33
annotation: SIP70ECA955609517C4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/223
classified with: http://purl.uniprot.org/keywords/408
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/486
classified with: http://purl.uniprot.org/keywords/533
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0005634
classified with: GO_0010308
classified with: GO_0010309
classified with: GO_0005506
classified with: GO_0016151
classified with: GO_0019509
classified with: GO_0006555
sequence: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN
proteome: Unassembled WGS sequence

A9VCM7-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2107
type: Resource
database: eggNOG
comment: Eukaryota

cd02232
type: Resource
database: CDD
comment: cupin_ARD
signature sequence match: CDD cd02232 match 1

http://purl.uniprot.org/gene3d/2.60.120.10
type: Resource
database: Gene3D
comment: Jelly Rolls
signature sequence match: Gene3D 2.60.120.10 match 1

MF_03154
type: Resource
database: HAMAP
comment: Salvage_MtnD_euk
signature sequence match: HAMAP MF 03154 match 1

IPR004313
type: Resource
database: InterPro
comment: ARD

IPR027496
type: Resource
database: InterPro
comment: ARD_euk

IPR014710
type: Resource
database: InterPro
comment: RmlC-like_jellyroll

IPR011051
type: Resource
database: InterPro
comment: RmlC_Cupin_sf

PTHR23418:SF0
type: Resource
database: PANTHER
comment: 1,2-DIHYDROXY-3-KETO-5-METHYLTHIOPENTENE DIOXYGENASE
signature sequence match: PANTHER PTHR23418:SF0 match 1

PTHR23418
type: Resource
database: PANTHER
comment: ACIREDUCTONE DIOXYGENASE
signature sequence match: PANTHER PTHR23418 match 1

PF03079
type: Resource
database: Pfam
comment: ARD
signature sequence match: Pfam PF03079 match 1

SSF51182
type: Resource
database: SUPFAM
comment: RmlC-like cupins
signature sequence match: SUPFAM SSF51182 match 1

SIP6C4F507236151752
type: Structured Name
full name: Acireductone dioxygenase

SIPC0D160E1090886D0
type: Structured Name
full name: Acireductone dioxygenase (Fe(2+)-requiring)
short name: ARD'
short name: Fe-ARD
ec name: 1.13.11.54

SIPC9EB0D8DEB78CD5E
type: Structured Name
full name: Acireductone dioxygenase (Ni(2+)-requiring)
short name: ARD
short name: Ni-ARD
ec name: 1.13.11.53

http://purl.uniprot.org/uniprot/A9VCM7#gene-MD51BE5236C36448329CD54281867760103
type: Gene
orf name: 12562

SIPF8F17208FC72F26C
type: Function Annotation
comment: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.

SIP231B8905F4C5321E
type: Cofactor Annotation
comment: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
cofactor: CHEBI_29033
cofactor: CHEBI_49786

SIP416FDE7A2D2C4378
type: Similarity Annotation
comment: Belongs to the acireductone dioxygenase (ARD) family.

PRO_0000414340
type: Chain Annotation
comment: Acireductone dioxygenase
mass: 20729
range: 18358916145297198tt1tt176

18358916145297198tt1
type: Position
type: ExactPosition
position: 1
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

18358916145297198tt176
type: Position
type: ExactPosition
position: 176
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

18358916145297198tt87
type: Position
type: ExactPosition
position: 87
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

18358916145297198tt89
type: Position
type: ExactPosition
position: 89
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

18358916145297198tt93
type: Position
type: ExactPosition
position: 93
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

18358916145297198tt132
type: Position
type: ExactPosition
position: 132
reference: MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN

SIPD0E51400B136DA88
subclass of: CHEBI_29033
comment: for iron-dependent acireductone dioxygenase activity

SIP5DFD3452AB516884
subclass of: CHEBI_49786
comment: for nickel-dependent acireductone dioxygenase activity

MKSWYMADVPEGGDPREPYMTDPLQEVSAEQLKALGVLYWHIPVEDHEEKLKAVCDERNYAAQDMITCSREKLPNYEDKLKTFFTEHLHEDEEIRYVTAGTGYFDVRSKDDRWIRIQVQPGDLLILPSGIYHRFTLDTDNYIQAKRLFQAEPKWTPINRPADDNSFRVEYLKALQN
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 20729

http://purl.uniprot.org/uniprot/A9VCM7#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9VCM7#attribution-69358FA1F7328576906CB1ED666FD320
manual: true
evidence: ECO_0000255
source: MF_03154

A9V2C1
type: Protein
reviewed: true
created: 2009-11-24
modified: 2023-02-22
version: 59
mnemonic: NHAAB_MONBE
citation: http://purl.uniprot.org/citations/18273011
citation: http://purl.uniprot.org/citations/19096720
recommended name: SIP0FDC83196FC1FDCF
enzyme: http://purl.uniprot.org/enzyme/4.2.1.84
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP0DE2802D95F0F7F0
annotation: SIP4FCA6C94737024B8
annotation: SIPBBB234F18161A0E5
annotation: SIPC1C99652DA712ED3
annotation: SIP73263FC949D71F9E
annotation: SIP24B735BD92F5542C
annotation: SIP1BA24434C24535E0
annotation: PRO_0000389131
annotation: SIP2A973485BD46009D
annotation: SIP81335E44BECE587E
annotation: SIP197BD3BCEC29034C
annotation: SIP42615929423F2880
annotation: SIP31FDF3EA40EFC429
annotation: SIPFC2DD0952BC326F7
annotation: SIP2438F406BAAA20BD
annotation: SIP13B3C107BBD1A241
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/408
classified with: http://purl.uniprot.org/keywords/456
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/558
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0080109
classified with: GO_0046914
classified with: GO_0006807
sequence: A9V2C1-1
proteome: Unassembled WGS sequence

A9V2C1-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

A9V2C1-citation-19096720
type: Citation Statement
scope: IDENTIFICATION

ENOG502S164
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/brenda/4.2.1.84
type: Resource
database: BRENDA
comment: 7932

http://purl.uniprot.org/gene3d/3.90.330.10
type: Resource
database: Gene3D
comment: Nitrile hydratase alpha /Thiocyanate hydrolase gamma
signature sequence match: Gene3D 3.90.330.10 match 1

http://purl.uniprot.org/gene3d/1.10.472.20
type: Resource
database: Gene3D
comment: Nitrile hydratase, beta subunit
signature sequence match: Gene3D 1.10.472.20 match 1

IPR036648
type: Resource
database: InterPro
comment: CN_Hdrase_a/SCN_Hdrase_g_sf

IPR004232
type: Resource
database: InterPro
comment: CN_Hdrtase_a/SCN_Hdrlase_g

IPR042262
type: Resource
database: InterPro
comment: CN_hydtase_beta_C

IPR024690
type: Resource
database: InterPro
comment: CN_hydtase_beta_dom

IPR008990
type: Resource
database: InterPro
comment: Elect_transpt_acc-like_dom_sf

PF02979
type: Resource
database: Pfam
comment: NHase_alpha
signature sequence match: Pfam PF02979 match 1

PF02211
type: Resource
database: Pfam
comment: NHase_beta
signature sequence match: Pfam PF02211 match 1
signature sequence match: Pfam PF02211 match 2

SSF50090
type: Resource
database: SUPFAM
comment: Electron transport accessory proteins
signature sequence match: SUPFAM SSF50090 match 1

SSF56209
type: Resource
database: SUPFAM
comment: Nitrile hydratase alpha chain
signature sequence match: SUPFAM SSF56209 match 1

SIP0FDC83196FC1FDCF
type: Structured Name
full name: Probable nitrile hydratase
short name: NHase
short name: Nitrilase
ec name: 4.2.1.84

http://purl.uniprot.org/uniprot/A9V2C1#gene-MD5609F6F8F84290A15417D40B4F48A00EF
type: Gene
orf name: 37534

SIP0DE2802D95F0F7F0
type: Function Annotation
comment: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class (By similarity).

SIPBBB234F18161A0E5
type: Cofactor Annotation
comment: Binds 1 Fe(3+) ion per subunit.
cofactor: CHEBI_29034

SIPC1C99652DA712ED3
type: PTM Annotation
comment: Oxidation on Cys-403 is essential for the activity.

SIP73263FC949D71F9E
type: PTM Annotation
comment: Oxidation on Cys-405 stabilizes the Fe-NO ligand coordinated in the inactive form.

SIP24B735BD92F5542C
type: Similarity Annotation
comment: In the N-terminal section; belongs to the nitrile hydratase subunit alpha family.

SIP1BA24434C24535E0
type: Similarity Annotation
comment: In the C-terminal section; belongs to the nitrile hydratase subunit beta family.

PRO_0000389131
type: Chain Annotation
comment: Probable nitrile hydratase
mass: 55604
range: 18358915859427630tt1tt496

18358915859427630tt1
type: Position
type: ExactPosition
position: 1
reference: A9V2C1-1

18358915859427630tt496
type: Position
type: ExactPosition
position: 496
reference: A9V2C1-1

SIP2A973485BD46009D
type: Region Annotation
comment: Disordered
range: 18358915859427630tt229tt269

18358915859427630tt229
type: Position
type: ExactPosition
position: 229
reference: A9V2C1-1

18358915859427630tt269
type: Position
type: ExactPosition
position: 269
reference: A9V2C1-1

SIP81335E44BECE587E
type: Compositional Bias Annotation
comment: Basic residues
range: 18358915859427630tt237tt261

18358915859427630tt237
type: Position
type: ExactPosition
position: 237
reference: A9V2C1-1

18358915859427630tt261
type: Position
type: ExactPosition
position: 261
reference: A9V2C1-1

18358915859427630tt400
type: Position
type: ExactPosition
position: 400
reference: A9V2C1-1

18358915859427630tt403
type: Position
type: ExactPosition
position: 403
reference: A9V2C1-1

18358915859427630tt404
type: Position
type: ExactPosition
position: 404
reference: A9V2C1-1

18358915859427630tt405
type: Position
type: ExactPosition
position: 405
reference: A9V2C1-1

SIP2438F406BAAA20BD
type: Modified Residue Annotation
comment: Cysteine sulfinic acid (-SO2H)
range: 18358915859427630tt403tt403

SIP13B3C107BBD1A241
type: Modified Residue Annotation
comment: Cysteine sulfenic acid (-SOH)
range: 18358915859427630tt405tt405

A9V2C1-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 55604
value: MHLFTYDLHHDVGGAENMLRLPLDRHERDYLPWERHIHALVVLLVKQGRMSVDELRRGVEGLPSSLAEQASYYEKWGLSVSRILTEKGTVSGHELEQGFLGVPTTDLPQVPRFQVGQRVMVRPFGTTFAYRQPHLRVPGYVHGAVGTIVELPGLFQDPMTGAYGERGTAQPLYRVAFSHRALWPEGAAHAEPGELEDGVVVDVSQPWLEALSEADYAQRLATLHRVAFTPDSNPPQAHKHHHHRHHHDHHHHHHHHHAMHAEHEAHTHDTRYGTEQAAVAKEAALDFPYQPWCEALVQTLTRRGVVRSDELHATLASLDALQNSGAGPQLVARAWSDAAFAEWLLTDAAAAAESLAIRTTNYDADPASAERVGGHRLFSHNHTELRVVANTDTVHNLVCCTLCSCYPTAILGLSPPWYKSKVFRARAVREPRRLLREEFGLVLPEARGIRVHDSTADLRYMVLPQRPQGTEGWSEEHLRTIVTRDSLLGTAVPRVD

http://purl.uniprot.org/uniprot/A9V2C1#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9V2C1#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9V7A1
type: Protein
reviewed: true
created: 2009-09-01
modified: 2023-05-03
version: 62
mnemonic: NUBP2_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP19636D702BD27E11
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP7D764134D99A2FF9
annotation: SIP9152602189A1D5CC
annotation: SIPCAE97E38E57DF63E
annotation: SIPEEC33B31F1974227
annotation: SIP54BF0BD1069E5570
annotation: PRO_0000382723
annotation: SIPF83EED4194F93C33
annotation: SIP12144C5F257F523D
annotation: SIP22A7C66D91D848E0
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/4
classified with: http://purl.uniprot.org/keywords/67
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005829
classified with: GO_0051539
classified with: GO_0005524
classified with: GO_0140663
classified with: GO_0051536
classified with: GO_0046872
classified with: GO_0016226
sequence: A9V7A1-1
proteome: Unassembled WGS sequence

A9V7A1-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3022
type: Resource
database: eggNOG
comment: Eukaryota

cd02037
type: Resource
database: CDD
comment: Mrp_NBP35
signature sequence match: CDD cd02037 match 1

http://purl.uniprot.org/gene3d/3.40.50.300
type: Resource
database: Gene3D
comment: P-loop containing nucleotide triphosphate hydrolases
signature sequence match: Gene3D 3.40.50.300 match 1

MF_02040
type: Resource
database: HAMAP
comment: Mrp_NBP35
signature sequence match: HAMAP MF 02040 match 1

MF_03039
type: Resource
database: HAMAP
comment: NUBP2
signature sequence match: HAMAP MF 03039 match 1

IPR019591
type: Resource
database: InterPro
comment: Mrp/NBP35_ATP-bd

IPR028600
type: Resource
database: InterPro
comment: NUBP2/Cfd1_eukaryotes

IPR027417
type: Resource
database: InterPro
comment: P-loop_NTPase

IPR033756
type: Resource
database: InterPro
comment: YlxH/NBP35

PTHR23264:SF19
type: Resource
database: PANTHER
comment: CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2
signature sequence match: PANTHER PTHR23264:SF19 match 1

PTHR23264
type: Resource
database: PANTHER
comment: NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED
signature sequence match: PANTHER PTHR23264 match 1

PF10609
type: Resource
database: Pfam
comment: ParA
signature sequence match: Pfam PF10609 match 1

SSF52540
type: Resource
database: SUPFAM
comment: P-loop containing nucleoside triphosphate hydrolases
signature sequence match: SUPFAM SSF52540 match 1

SIP19636D702BD27E11
type: Structured Name
full name: Cytosolic Fe-S cluster assembly factor NUBP2 homolog

http://purl.uniprot.org/uniprot/A9V7A1#gene-MD5BAE69B7D00455245E4E55AE51B6233A8
type: Gene
orf name: 33756

SIP7D764134D99A2FF9
type: Function Annotation
comment: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.

SIP9152602189A1D5CC
type: Cofactor Annotation
comment: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
cofactor: CHEBI_49883

SIPCAE97E38E57DF63E
type: Subunit Annotation
comment: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

SIP54BF0BD1069E5570
type: Similarity Annotation
comment: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.

PRO_0000382723
type: Chain Annotation
comment: Cytosolic Fe-S cluster assembly factor NUBP2 homolog
mass: 30376
range: 18358915943182638tt1tt284

18358915943182638tt1
type: Position
type: ExactPosition
position: 1
reference: A9V7A1-1

18358915943182638tt284
type: Position
type: ExactPosition
position: 284
reference: A9V7A1-1

18358915943182638tt27
type: Position
type: ExactPosition
position: 27
reference: A9V7A1-1

18358915943182638tt34
type: Position
type: ExactPosition
position: 34
reference: A9V7A1-1

18358915943182638tt200
type: Position
type: ExactPosition
position: 200
reference: A9V7A1-1

18358915943182638tt203
type: Position
type: ExactPosition
position: 203
reference: A9V7A1-1

SIPE18D463B165C7C72
subclass of: CHEBI_49883
comment: ligand shared between dimeric partners

A9V7A1-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 30376
value: MAAPNEFYETLKQRLAGVKHIVLVLSGKGGVGKSTVASQMAIGLIHRGLKVGLLDIDLTGPSIPTMFGVADQQVHTSSEGWVPLYKYDQRLAIMSIGFLLDSRDEAVIWRGPKKNAMIQQFLSEVCWDELDCLVVDTPPGTSDEHLSIVDALKLCKPDGAILVTTPQGVALSDVRREAEFCRKARLKVLGVVENMSGFACPHCKDCTNLFSKGGGEKLAQEIAAPFLGAIPIDPMLGQSLSRGEDFLASCQAAPSYEAVAALIDPLMAQLGLVQATADTSTPSH

http://purl.uniprot.org/uniprot/A9V7A1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V7A1#attribution-6CED2D6D346A740272B05F8EF9EAE773
manual: true
evidence: ECO_0000255
source: MF_03039

A9URZ4
type: Protein
reviewed: true
created: 2009-05-05
modified: 2023-05-03
version: 65
mnemonic: PESC_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPFD5457DDD06CD4EC
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPFC011649779E69F7
annotation: SIP1DF4684B598368DA
annotation: SIP2D658B0C3C82AB58
annotation: PRO_0000370468
annotation: SIP69CA3863C46EBF6F
annotation: SIP0053A45F6982AD5C
annotation: SIP893B05CB1B3AFC7F
annotation: SIP3FB4D22B14729380
annotation: SIP249890C612A8B70F
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/175
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/690
classified with: http://purl.uniprot.org/keywords/698
classified with: GO_0005654
classified with: GO_0070545
classified with: GO_0030687
classified with: GO_0043021
classified with: GO_0003723
classified with: GO_0000466
classified with: GO_0000463
sequence: A9URZ4-1
proteome: Unassembled WGS sequence

A9URZ4-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2481
type: Resource
database: eggNOG
comment: Eukaryota

cd17709
type: Resource
database: CDD
comment: BRCT_pescadillo_like
signature sequence match: CDD cd17709 match 1

http://purl.uniprot.org/gene3d/3.40.50.10190
type: Resource
database: Gene3D
comment: BRCT domain
signature sequence match: Gene3D 3.40.50.10190 match 1

MF_03028
type: Resource
database: HAMAP
comment: Pescadillo
signature sequence match: HAMAP MF 03028 match 1

IPR001357
type: Resource
database: InterPro
comment: BRCT_dom

IPR036420
type: Resource
database: InterPro
comment: BRCT_dom_sf

IPR010613
type: Resource
database: InterPro
comment: PES

PTHR12221
type: Resource
database: PANTHER
comment: PESCADILLO - RELATED
signature sequence match: PANTHER PTHR12221 match 1

PTHR12221:SF6
type: Resource
database: PANTHER
comment: PESCADILLO HOMOLOG
signature sequence match: PANTHER PTHR12221:SF6 match 1

PF16589
type: Resource
database: Pfam
comment: BRCT_2
signature sequence match: Pfam PF16589 match 1

PF06732
type: Resource
database: Pfam
comment: Pescadillo_N
signature sequence match: Pfam PF06732 match 1

SM00292
type: Resource
database: SMART
comment: BRCT
signature sequence match: SMART SM00292 match 1

SSF52113
type: Resource
database: SUPFAM
comment: BRCT domain
signature sequence match: SUPFAM SSF52113 match 1

PS50172
type: Resource
database: PROSITE
comment: BRCT
signature sequence match: PROSITE PS50172 match 1

SIPFD5457DDD06CD4EC
type: Structured Name
full name: Pescadillo homolog

http://purl.uniprot.org/uniprot/A9URZ4#gene-MD5C6502B6520E5DB75CFAABA4019072D43
type: Gene
orf name: 19511

SIPFC011649779E69F7
type: Function Annotation
comment: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

SIP2D658B0C3C82AB58
type: Similarity Annotation
comment: Belongs to the pescadillo family.

PRO_0000370468
type: Chain Annotation
comment: Pescadillo homolog
mass: 67430
range: 18358912102839342tt1tt589

18358912102839342tt1
type: Position
type: ExactPosition
position: 1
reference: A9URZ4-1

18358912102839342tt589
type: Position
type: ExactPosition
position: 589
reference: A9URZ4-1

SIP69CA3863C46EBF6F
type: Domain Extent Annotation
comment: BRCT
range: 18358912102839342tt346tt440

18358912102839342tt346
type: Position
type: ExactPosition
position: 346
reference: A9URZ4-1

18358912102839342tt440
type: Position
type: ExactPosition
position: 440
reference: A9URZ4-1

SIP0053A45F6982AD5C
type: Region Annotation
comment: Disordered
range: 18358912102839342tt287tt309

18358912102839342tt287
type: Position
type: ExactPosition
position: 287
reference: A9URZ4-1

18358912102839342tt309
type: Position
type: ExactPosition
position: 309
reference: A9URZ4-1

SIP893B05CB1B3AFC7F
type: Region Annotation
comment: Disordered
range: 18358912102839342tt503tt589

18358912102839342tt503
type: Position
type: ExactPosition
position: 503
reference: A9URZ4-1

18358912102839342tt261
type: Position
type: ExactPosition
position: 261
reference: A9URZ4-1

18358912102839342tt305
type: Position
type: ExactPosition
position: 305
reference: A9URZ4-1

18358912102839342tt520
type: Position
type: ExactPosition
position: 520
reference: A9URZ4-1

18358912102839342tt587
type: Position
type: ExactPosition
position: 587
reference: A9URZ4-1

A9URZ4-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 67430
value: MGRIKKKGEEGTATEYMSRSRAVRKLQLSLADFRRLCILKGIYPREPPNKKKVTGSTANRTYYFVKDINWLLHEPLLQRFRELKTYARRLKKAEAKDQPGVVKAIRRREPKVKVNHLVKERYPSFVDAIRDLDDCLCMLFLFASFPQTGVIRARMVEKCRRLCNEFMLYVVRARALRKVFLSIKGIYYQAEIMGQTVTWIAPYQFATDVPTDVDFRVMGTFLQFYLTLLGFVNFKLYATLGMHYPPQFEAAQSEASETMSKHHRKQAKKTESRVAQALADVKAAMDEDLNDEEEELDAQTKQEAAPADRDQASFDTFEAMADPAVDSDMNVPSGQDLEEAAAEADAATRIFQNLYFFLSREVPRYSLEFVIRSFGGNVSWDALDEAEAGPYGVDDPRITHHIVDRPAVSQTFDGRHYVQPQWVYDCINAKALLPTSTYTLGAVLPPHLSPFVEEGADDYMPPERRAQLAAAKNIHSTDMTIDESEAPEEIDDEDIYRKELEAELRGDDTAEAPEEPKGNTAKRKKTKAEKGKAAEEERKEMAKLMMSKRDRTLYNRIVHSKKQKQVEAQKLTARRQQIDKEKSAKKSKK

http://purl.uniprot.org/uniprot/A9URZ4#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9URZ4#attribution-A5CE20FC80FC07C28617C998D851486D
manual: true
evidence: ECO_0000255
source: MF_03028

A9UTP3
type: Protein
reviewed: true
created: 2010-10-05
modified: 2023-09-13
version: 72
mnemonic: PURA_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP8FA2BE9F6E6392A5
alternative name: SIPF1A8AB9C8AEB85E2
enzyme: http://purl.uniprot.org/enzyme/6.3.4.4
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP9B9FB853F7E4AD29
annotation: SIP0DF99014F2415165
annotation: SIP78F62E86C167B2F0
annotation: SIP82A8550345F54172
annotation: SIP4A95CA2CFED5B4AD
annotation: SIP47057486803FC788
annotation: SIPA65FDDFF7E7CAE58
annotation: PRO_0000399311
annotation: SIP0AEFC5D042C7F469
annotation: SIPE8AC5DB371050187
annotation: SIP085C86A64109A666
annotation: SIPF273A4F6A3ED6081
annotation: SIP3362EAFD4D2E467E
annotation: SIPBEAC195CB67676FA
annotation: SIPA83FD12802FBCA97
annotation: SIP58DDBEA1DBC26B07
annotation: SIP2D7A42B417AD0C64
annotation: SIPC68B3ACF5B7BCB1C
annotation: SIP72D402D6AADAC60D
annotation: SIP63EE7857286F4A66
annotation: SIPE5A4BFDCFE5E0E7F
annotation: SIP7B0A50B63AB11727
annotation: SIPF46E7BC8B32EC316
annotation: SIP5381AED795BF55A6
annotation: SIPF5BDF78C18484871
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/658
classified with: http://purl.uniprot.org/keywords/1185
classified with: GO_0005737
classified with: GO_0004019
classified with: GO_0005525
classified with: GO_0000287
classified with: GO_0044208
classified with: GO_0046040
sequence: A9UTP3-1
proteome: Unassembled WGS sequence

A9UTP3-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1355
type: Resource
database: eggNOG
comment: Eukaryota

cd03108
type: Resource
database: CDD
comment: AdSS
signature sequence match: CDD cd03108 match 1

http://purl.uniprot.org/gene3d/3.40.440.10
type: Resource
database: Gene3D
comment: Adenylosuccinate Synthetase, subunit A, domain 1
signature sequence match: Gene3D 3.40.440.10 match 1

http://purl.uniprot.org/gene3d/1.10.300.10
type: Resource
database: Gene3D
comment: Adenylosuccinate Synthetase, subunit A, domain 2
signature sequence match: Gene3D 1.10.300.10 match 1

http://purl.uniprot.org/gene3d/3.90.170.10
type: Resource
database: Gene3D
comment: Adenylosuccinate Synthetase, subunit A, domain 3
signature sequence match: Gene3D 3.90.170.10 match 1

MF_00011
type: Resource
database: HAMAP
comment: Adenylosucc_synth
signature sequence match: HAMAP MF 00011 match 1

IPR018220
type: Resource
database: InterPro
comment: Adenylosuccin_syn_GTP-bd

IPR033128
type: Resource
database: InterPro
comment: Adenylosuccin_syn_Lys_AS

IPR042109
type: Resource
database: InterPro
comment: Adenylosuccinate_synth_dom1

IPR042110
type: Resource
database: InterPro
comment: Adenylosuccinate_synth_dom2

IPR042111
type: Resource
database: InterPro
comment: Adenylosuccinate_synth_dom3

IPR001114
type: Resource
database: InterPro
comment: Adenylosuccinate_synthetase

TIGR00184
type: Resource
database: NCBIfam
comment: purA
signature sequence match: NCBIfam TIGR00184 match 1

PTHR11846
type: Resource
database: PANTHER
comment: ADENYLOSUCCINATE SYNTHETASE
signature sequence match: PANTHER PTHR11846 match 1

PTHR11846:SF0
type: Resource
database: PANTHER
comment: ADENYLOSUCCINATE SYNTHETASE
signature sequence match: PANTHER PTHR11846:SF0 match 1

PF00709
type: Resource
database: Pfam
comment: Adenylsucc_synt
signature sequence match: Pfam PF00709 match 1

SM00788
type: Resource
database: SMART
comment: Adenylsucc_synt
signature sequence match: SMART SM00788 match 1

PS01266
type: Resource
database: PROSITE
comment: ADENYLOSUCCIN_SYN_1
signature sequence match: PROSITE PS01266 match 1

PS00513
type: Resource
database: PROSITE
comment: ADENYLOSUCCIN_SYN_2
signature sequence match: PROSITE PS00513 match 1

SIP8FA2BE9F6E6392A5
type: Structured Name
full name: Adenylosuccinate synthetase
short name: AMPSase
short name: AdSS
ec name: 6.3.4.4

SIPF1A8AB9C8AEB85E2
type: Structured Name
full name: IMP--aspartate ligase

http://purl.uniprot.org/uniprot/A9UTP3#gene-MD5E28E125CA9992C2D048E17D25A459C67
type: Gene
orf name: 20027

SIP9B9FB853F7E4AD29
type: Function Annotation
comment: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

SIP78F62E86C167B2F0
type: Cofactor Annotation
comment: Binds 1 Mg(2+) ion per subunit.
cofactor: CHEBI_18420

SIP4A95CA2CFED5B4AD
type: Subunit Annotation
comment: Homodimer.

SIPA65FDDFF7E7CAE58
type: Similarity Annotation
comment: Belongs to the adenylosuccinate synthetase family.

PRO_0000399311
type: Chain Annotation
comment: Adenylosuccinate synthetase
mass: 47271
range: 18358912135738158tt1tt431

18358912135738158tt1
type: Position
type: ExactPosition
position: 1
reference: A9UTP3-1

18358912135738158tt431
type: Position
type: ExactPosition
position: 431
reference: A9UTP3-1

SIP0AEFC5D042C7F469
type: Active Site Annotation
comment: Proton acceptor
range: 18358912135738158tt16tt16

18358912135738158tt16
type: Position
type: ExactPosition
position: 16
reference: A9UTP3-1

SIPE8AC5DB371050187
type: Active Site Annotation
comment: Proton donor
range: 18358912135738158tt44tt44

18358912135738158tt44
type: Position
type: ExactPosition
position: 44
reference: A9UTP3-1

18358912135738158tt15
type: Position
type: ExactPosition
position: 15
reference: A9UTP3-1

18358912135738158tt21
type: Position
type: ExactPosition
position: 21
reference: A9UTP3-1

SIPF273A4F6A3ED6081
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt16tt19

18358912135738158tt19
type: Position
type: ExactPosition
position: 19
reference: A9UTP3-1

SIPBEAC195CB67676FA
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt41tt44

18358912135738158tt41
type: Position
type: ExactPosition
position: 41
reference: A9UTP3-1

18358912135738158tt43
type: Position
type: ExactPosition
position: 43
reference: A9UTP3-1

18358912135738158tt45
type: Position
type: ExactPosition
position: 45
reference: A9UTP3-1

SIP2D7A42B417AD0C64
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt135tt135

18358912135738158tt135
type: Position
type: ExactPosition
position: 135
reference: A9UTP3-1

18358912135738158tt149
type: Position
type: ExactPosition
position: 149
reference: A9UTP3-1

SIP72D402D6AADAC60D
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt227tt227

18358912135738158tt227
type: Position
type: ExactPosition
position: 227
reference: A9UTP3-1

SIP63EE7857286F4A66
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt242tt242

18358912135738158tt242
type: Position
type: ExactPosition
position: 242
reference: A9UTP3-1

18358912135738158tt302
type: Position
type: ExactPosition
position: 302
reference: A9UTP3-1

18358912135738158tt308
type: Position
type: ExactPosition
position: 308
reference: A9UTP3-1

SIP7B0A50B63AB11727
type: Binding Site Annotation
comment: in other chain
ligand: SIP14916F19539BE819
range: 18358912135738158tt306tt306

18358912135738158tt306
type: Position
type: ExactPosition
position: 306
reference: A9UTP3-1

18358912135738158tt334
type: Position
type: ExactPosition
position: 334
reference: A9UTP3-1

18358912135738158tt336
type: Position
type: ExactPosition
position: 336
reference: A9UTP3-1

18358912135738158tt416
type: Position
type: ExactPosition
position: 416
reference: A9UTP3-1

18358912135738158tt418
type: Position
type: ExactPosition
position: 418
reference: A9UTP3-1

SIP14916F19539BE819
subclass of: CHEBI_58053
comment: ligand shared between dimeric partners

substrate

A9UTP3-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 47271
value: MAQQKVAVVLGLQWGDEGKGKLVDVLAEDADVVARFAGGNNAGHTVVVDNISYDFHLLPSGIGHAKCDCVIGNGVVIHLPGLYEEVEKNMAKGPHLQGWQSRLKISDRAHLVLDLHQKVDGMKEEERGLDKIGTTKKGIGPTYSSKAIRHGLRVCDLMGDFGIFKQKFLQVVEHYQKLFPSLEVDVDAQLKAFEGYAEKVRPMVTDTTLLVHRYLKENKRVLLEGANATMLDLDFGTYPYVTSSSCCVGGICTGLGLPPQAVGDVYGVVKAYTTRVGDGAFPTEDFAEVGNYLQTKGHEYGVTTGRKRRCGWLDMMVVNYACMINGVTKICLTKLDVLDELETIKIAVAYKKGGEALLGMPASQQVLNEVEVEYVDMPGWQTNISEIRDFEALPTQAQAYVRKVEELSGVPVKWIGVGPAREAMIIVPPRQ

http://purl.uniprot.org/uniprot/A9UTP3#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UTP3#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UTP3#attribution-70A1D00530B067331C26A7BED4214158
manual: true
evidence: ECO_0000255
source: MF_03125

A9USH8
type: Protein
reviewed: true
created: 2009-11-24
modified: 2023-06-28
version: 56
mnemonic: RS3A_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIPFC9838476EBF663B
alternative name: SIPEC60292E4D7BEE60
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPDDBFBD8846080EC6
annotation: SIPEC6CAF2276AD6063
annotation: SIPD1DAA86590EE9B39
annotation: SIP68D439A8BD2E33CC
annotation: PRO_0000389422
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/689
classified with: GO_0005829
classified with: GO_0022627
classified with: GO_0003735
classified with: GO_0006412
sequence: A9USH8-1
proteome: Unassembled WGS sequence

A9USH8-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1628
type: Resource
database: eggNOG
comment: Eukaryota

MF_03122
type: Resource
database: HAMAP
comment: Ribosomal_S3Ae_euk
signature sequence match: HAMAP MF 03122 match 1

IPR027500
type: Resource
database: InterPro
comment: Ribosomal_S1/3_euk

IPR001593
type: Resource
database: InterPro
comment: Ribosomal_S3Ae

IPR018281
type: Resource
database: InterPro
comment: Ribosomal_S3Ae_CS

PTHR11830
type: Resource
database: PANTHER
comment: 40S RIBOSOMAL PROTEIN S3A
signature sequence match: PANTHER PTHR11830 match 1

PTHR11830:SF0
type: Resource
database: PANTHER
comment: 40S RIBOSOMAL PROTEIN S3A
signature sequence match: PANTHER PTHR11830:SF0 match 1

PF01015
type: Resource
database: Pfam
comment: Ribosomal_S3Ae
signature sequence match: Pfam PF01015 match 1

SM01397
type: Resource
database: SMART
comment: Ribosomal_S3Ae
signature sequence match: SMART SM01397 match 1

PS01191
type: Resource
database: PROSITE
comment: RIBOSOMAL_S3AE
signature sequence match: PROSITE PS01191 match 1

SIPFC9838476EBF663B
type: Structured Name
full name: Small ribosomal subunit protein eS1

SIPEC60292E4D7BEE60
type: Structured Name
full name: 40S ribosomal protein S3a

http://purl.uniprot.org/uniprot/A9USH8#gene-MD55D8677D65BD381421190615B041961BB
type: Gene
orf name: 34920

SIPDDBFBD8846080EC6
type: Subunit Annotation
comment: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).

SIPD1DAA86590EE9B39
type: Similarity Annotation
comment: Belongs to the eukaryotic ribosomal protein eS1 family.

SIP68D439A8BD2E33CC
type: Initiator Methionine Annotation
comment: Removed
range: 18358912118437934tt1tt1

18358912118437934tt1
type: Position
type: ExactPosition
position: 1
reference: A9USH8-1

PRO_0000389422
type: Chain Annotation
comment: Small ribosomal subunit protein eS1
mass: 29062
range: 18358912118437934tt2tt259

18358912118437934tt2
type: Position
type: ExactPosition
position: 2
reference: A9USH8-1

18358912118437934tt259
type: Position
type: ExactPosition
position: 259
reference: A9USH8-1

A9USH8-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 29193
value: MAVGKNKKLMKGKKGGKKKVVDVFTKKEWYDVKAPSYFKKRQVGKTPVNRTAGTKLSADGLRGRVYEMSLADLNDDESTFRKVKLQVEEIQGTECLTNFHGMSLTTDKLRSLVKKWRSLIEAFVDVKTNDGYVLRIFSIGFTKKQANSDRKTCYAQSAQKRALRAKMVEIMQREATCDLKEFVSKLMPGTIGQEIQKKCQSIFPLQDVYIRKVKVLKKPRFDVSKLLELHGEAGGVTADKGKTVAKSGEFVEPKPQTSV

http://purl.uniprot.org/uniprot/A9USH8#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9USH8#attribution-AA28E5F73D9840F44EA7D3CF8C2546F6
manual: true
evidence: ECO_0000255
source: MF_03122

http://purl.uniprot.org/uniprot/A9USH8#attribution-8E46A4482B9627E70753146E6F0A49F8
manual: true
evidence: ECO_0000305

A9UPA2
type: Protein
reviewed: true
created: 2009-05-05
modified: 2023-09-13
version: 68
mnemonic: RSSA_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP8AD0AAE16D340C27
alternative name: SIPE6741D25792C9A9E
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP97D28C255C20C2F8
annotation: SIPD57E9D224BB9F2C2
annotation: SIP90D7A0A0A210A09C
annotation: SIP318A03CB17F14B2B
annotation: PRO_0000371656
annotation: SIPEE8995D8DBDF180A
annotation: SIPF6B5F59C1C15CFE6
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/963
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/689
classified with: GO_0022627
classified with: GO_0003735
classified with: GO_0002181
classified with: GO_0000028
sequence: A9UPA2-1
proteome: Unassembled WGS sequence

A9UPA2-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0830
type: Resource
database: eggNOG
comment: Eukaryota

cd01425
type: Resource
database: CDD
comment: RPS2
signature sequence match: CDD cd01425 match 1

MF_03015
type: Resource
database: HAMAP
comment: Ribosomal_S2_euk
signature sequence match: HAMAP MF 03015 match 1

IPR032281
type: Resource
database: InterPro
comment: 40S_SA_C

IPR001865
type: Resource
database: InterPro
comment: Ribosomal_S2

IPR018130
type: Resource
database: InterPro
comment: Ribosomal_S2_CS

IPR027498
type: Resource
database: InterPro
comment: Ribosomal_S2_euk

IPR005707
type: Resource
database: InterPro
comment: Ribosomal_S2_euk/arc

IPR023591
type: Resource
database: InterPro
comment: Ribosomal_S2_flav_dom_sf

TIGR01012
type: Resource
database: NCBIfam
comment: uS2_euk_arch
signature sequence match: NCBIfam TIGR01012 match 1

PTHR11489
type: Resource
database: PANTHER
comment: 40S RIBOSOMAL PROTEIN SA
signature sequence match: PANTHER PTHR11489 match 1

PTHR11489:SF9
type: Resource
database: PANTHER
comment: 40S RIBOSOMAL PROTEIN SA
signature sequence match: PANTHER PTHR11489:SF9 match 1

PF16122
type: Resource
database: Pfam
comment: 40S_SA_C
signature sequence match: Pfam PF16122 match 1

PF00318
type: Resource
database: Pfam
comment: Ribosomal_S2
signature sequence match: Pfam PF00318 match 1

PR00395
type: Resource
database: PRINTS
comment: RIBOSOMALS2

SSF52313
type: Resource
database: SUPFAM
comment: Ribosomal protein S2
signature sequence match: SUPFAM SSF52313 match 1

PS00962
type: Resource
database: PROSITE
comment: RIBOSOMAL_S2_1
signature sequence match: PROSITE PS00962 match 1

PS00963
type: Resource
database: PROSITE
comment: RIBOSOMAL_S2_2
signature sequence match: PROSITE PS00963 match 1

SIP8AD0AAE16D340C27
type: Structured Name
full name: Small ribosomal subunit protein uS2

SIPE6741D25792C9A9E
type: Structured Name
full name: 40S ribosomal protein SA

http://purl.uniprot.org/uniprot/A9UPA2#gene-MD55653689DC1E59BCCF46DFD32CC52FA9A
type: Gene
orf name: 30792

SIP97D28C255C20C2F8
type: Function Annotation
comment: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

SIPD57E9D224BB9F2C2
type: Subunit Annotation
comment: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.

SIP318A03CB17F14B2B
type: Similarity Annotation
comment: Belongs to the universal ribosomal protein uS2 family.

PRO_0000371656
type: Chain Annotation
comment: Small ribosomal subunit protein uS2
mass: 30405
range: 18358912067645998tt1tt278

18358912067645998tt1
type: Position
type: ExactPosition
position: 1
reference: A9UPA2-1

18358912067645998tt278
type: Position
type: ExactPosition
position: 278
reference: A9UPA2-1

SIPEE8995D8DBDF180A
type: Region Annotation
comment: Disordered
range: 18358912067645998tt216tt235

18358912067645998tt216
type: Position
type: ExactPosition
position: 216
reference: A9UPA2-1

18358912067645998tt235
type: Position
type: ExactPosition
position: 235
reference: A9UPA2-1

SIPF6B5F59C1C15CFE6
type: Region Annotation
comment: Disordered
range: 18358912067645998tt250tt278

18358912067645998tt250
type: Position
type: ExactPosition
position: 250
reference: A9UPA2-1

A9UPA2-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 30405
value: MSEGFDILKPTEADIQKLLMAKVHLGASNCTTAMSKYVYKRRSDGVNVIDLNKTYEKIVLAARIIAAVDSPANVCAISGRNFGQRAILKFCNHIGGAFPIAGRFTPGAFTNQIQKAFQEPRLLVLTDPLVDHQAVREASYVNIPIISLCDVDAPLRYVDVVIPCNNKSPHAIGIVWWMLAREVLRLRGTLPRDAEWDVMPDLYFFRDPEEIKKEEEAAAAAKEAEDDTGYTTQWDDAALDADWSATGTGNFAAAPADGNWGATTGGDWAAAGGEEWTN

http://purl.uniprot.org/uniprot/A9UPA2#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UPA2#attribution-F889CA9F3C9EA463D3C6F72FEFE03E34
manual: true
evidence: ECO_0000255
source: MF_03015

http://purl.uniprot.org/uniprot/A9UPA2#attribution-8E46A4482B9627E70753146E6F0A49F8
manual: true
evidence: ECO_0000305

A9UXG6
type: Protein
reviewed: true
created: 2011-04-05
modified: 2023-02-22
version: 67
mnemonic: RTCB_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP5447891016986D29
alternative name: SIPABDBFA944DA4C3F7
enzyme: http://purl.uniprot.org/enzyme/6.5.1.8
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP5440F025927D6B48
annotation: SIPFE81E6073498AE2F
annotation: SIP93851DB97844AD92
annotation: SIP213AD0A87C79541E
annotation: SIP806BD7E105D93698
annotation: SIP5C2660B0BC38194D
annotation: SIP84384F74AC85CB70
annotation: PRO_0000407245
annotation: SIPD737CF1B5FD2C7E8
annotation: SIP8443A6468C768523
annotation: SIP74B12C9548AE47EE
annotation: SIP4B4C903F6B985F9C
annotation: SIPDFEB7F6102A5A4C2
annotation: SIP8EF65EB2DBC54413
annotation: SIP38B543333F1EF149
annotation: SIP6B79A57460FAEEE5
annotation: SIP7E466E22670D8242
annotation: SIPF84142EF5A474B67
annotation: SIP4A4742E3499224B4
annotation: SIP84B008310B303C45
annotation: SIPCD3A71F799B0528A
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/342
classified with: http://purl.uniprot.org/keywords/436
classified with: http://purl.uniprot.org/keywords/464
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/819
classified with: GO_0005634
classified with: GO_0072669
classified with: GO_0005525
classified with: GO_0046872
classified with: GO_0003972
classified with: GO_0000971
sequence: A9UXG6-1
proteome: Unassembled WGS sequence

A9UXG6-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3833
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.90.1860.10
type: Resource
database: Gene3D
comment: tRNA-splicing ligase RtcB
signature sequence match: Gene3D 3.90.1860.10 match 1

MF_03144
type: Resource
database: HAMAP
comment: RtcB_euk
signature sequence match: HAMAP MF 03144 match 1

IPR001233
type: Resource
database: InterPro
comment: RtcB

IPR036025
type: Resource
database: InterPro
comment: RtcB-like_sf

IPR027513
type: Resource
database: InterPro
comment: RtcB_euk

PTHR11118:SF1
type: Resource
database: PANTHER
comment: RNA-SPLICING LIGASE RTCB HOMOLOG
signature sequence match: PANTHER PTHR11118:SF1 match 1

PTHR11118
type: Resource
database: PANTHER
comment: UNCHARACTERIZED
signature sequence match: PANTHER PTHR11118 match 1

PF01139
type: Resource
database: Pfam
comment: RtcB
signature sequence match: Pfam PF01139 match 1

SSF103365
type: Resource
database: SUPFAM
comment: Hypothetical protein PH1602
signature sequence match: SUPFAM SSF103365 match 1

PS01288
type: Resource
database: PROSITE
comment: UPF0027
signature sequence match: PROSITE PS01288 match 1

SIP5447891016986D29
type: Structured Name
full name: RNA-splicing ligase RtcB homolog
ec name: 6.5.1.8

SIPABDBFA944DA4C3F7
type: Structured Name
full name: 3'-phosphate/5'-hydroxy nucleic acid ligase

http://purl.uniprot.org/uniprot/A9UXG6#gene-MD5995EAFC5512978E6E00E0C7EE77BDF5C
type: Gene
orf name: 24995

SIP5440F025927D6B48
type: Function Annotation
comment: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.

SIP213AD0A87C79541E
type: Cofactor Annotation
comment: Binds 2 manganese ions per subunit.
cofactor: CHEBI_29035

SIP806BD7E105D93698
type: Subunit Annotation
comment: Catalytic component of the tRNA-splicing ligase complex.

SIP5C2660B0BC38194D
type: Annotation
comment: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

SIP84384F74AC85CB70
type: Similarity Annotation
comment: Belongs to the RtcB family.

PRO_0000407245
type: Chain Annotation
comment: RNA-splicing ligase RtcB homolog
mass: 54297
range: 18358912202257966tt1tt497

18358912202257966tt1
type: Position
type: ExactPosition
position: 1
reference: A9UXG6-1

18358912202257966tt497
type: Position
type: ExactPosition
position: 497
reference: A9UXG6-1

SIPD737CF1B5FD2C7E8
type: Active Site Annotation
comment: GMP-histidine intermediate
range: 18358912202257966tt420tt420

18358912202257966tt420
type: Position
type: ExactPosition
position: 420
reference: A9UXG6-1

18358912202257966tt111
type: Position
type: ExactPosition
position: 111
reference: A9UXG6-1

18358912202257966tt114
type: Position
type: ExactPosition
position: 114
reference: A9UXG6-1

18358912202257966tt218
type: Position
type: ExactPosition
position: 218
reference: A9UXG6-1

18358912202257966tt222
type: Position
type: ExactPosition
position: 222
reference: A9UXG6-1

18358912202257966tt219
type: Position
type: ExactPosition
position: 219
reference: A9UXG6-1

18358912202257966tt251
type: Position
type: ExactPosition
position: 251
reference: A9UXG6-1

18358912202257966tt345
type: Position
type: ExactPosition
position: 345
reference: A9UXG6-1

18358912202257966tt346
type: Position
type: ExactPosition
position: 346
reference: A9UXG6-1

18358912202257966tt394
type: Position
type: ExactPosition
position: 394
reference: A9UXG6-1

18358912202257966tt397
type: Position
type: ExactPosition
position: 397
reference: A9UXG6-1

18358912202257966tt401
type: Position
type: ExactPosition
position: 401
reference: A9UXG6-1

18358912202257966tt423
type: Position
type: ExactPosition
position: 423
reference: A9UXG6-1

18358912202257966tt496
type: Position
type: ExactPosition
position: 496
reference: A9UXG6-1

1
subclass of: CHEBI_29035

2
subclass of: CHEBI_29035

A9UXG6-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 54297
value: MKYLERLTPSCWRIKPGFVPNMKVEGRFYVNKALEALMLEELQQFASARGVGGFLPAVKQIANVASLPGIVGASVGLPDVHSGYGFAIGNMAAFDMDDPEAIVSPGGVGFDINCGVRLLRTNLTLEDVEPVKEQLAQSLFDHIPVGVGSKGVIPMNAKDLEEALEMGMDWSLREGYAWAEDKEHCEEYGRMLQADASKVSARAKKRGLPQLGTLGAGNHYAEIQVVEEIYDKEAAAKMGINKKNQICVMIHSGSRGLGHQVATDALVAMEKAMKRDGIEVNDRQLACARIHSEEGQNYLKAMAAAANYAWVNRSTMTFLCRQAFAKQFNTTPEELDMHVIYDVSHNIAKTERHMVNGTERTLLVHRKGSTRAFPPHHPLIPVDYQLIGQPVLIGGTMGTCSYVLTGTDTGFRDTFGSTCHGAGRALSRAKSRRTLDYQQVLDKLDKKGIAIRVASPKLVMEEAPESYKDVTAVVDTCHAAGISKKVVKLRPIAVIKG

http://purl.uniprot.org/uniprot/A9UXG6#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UXG6#attribution-AAAF21F887E9DB11AF894A0A1F09ABA8
manual: true
evidence: ECO_0000255
source: MF_03144

A9UY97
type: Protein
reviewed: true
created: 2008-07-01
modified: 2023-05-03
version: 58
mnemonic: SERIC_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP76D764EBC56A8CA7
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPECCDD570CC70CB6E
annotation: SIPD5DCF81943D2DAED
annotation: SIP5F763D276430459D
annotation: PRO_0000342156
annotation: SIPF1193C1C05B9C660
annotation: SIPD69F905F4068E3BC
annotation: SIPE6A9A2B9F4507011
annotation: SIP9CF6BCB5435341D2
annotation: SIP8D59F63992DE6BF9
annotation: SIP799A6C5E848F4364
annotation: SIP488E275CBE545182
annotation: SIP239B79B9777AE0C2
annotation: SIP9CF1FDFD521BA28E
annotation: SIP4C42BC9DBAFE85F6
annotation: SIP83D4D8B1573E6E82
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/256
classified with: http://purl.uniprot.org/keywords/594
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005789
classified with: GO_0016020
classified with: GO_0008654
sequence: A9UY97-1
proteome: Unassembled WGS sequence

A9UY97-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2592
type: Resource
database: eggNOG
comment: Eukaryota

IPR005016
type: Resource
database: InterPro
comment: TDE1/TMS

PTHR10383
type: Resource
database: PANTHER
comment: SERINE INCORPORATOR
signature sequence match: PANTHER PTHR10383 match 1

PTHR10383:SF9
type: Resource
database: PANTHER
comment: TMS1, ISOFORM F
signature sequence match: PANTHER PTHR10383:SF9 match 1

PF03348
type: Resource
database: Pfam
comment: Serinc
signature sequence match: Pfam PF03348 match 1

SIP76D764EBC56A8CA7
type: Structured Name
full name: Probable serine incorporator

serinc
type: Gene
orf name: 18904

SIPECCDD570CC70CB6E
type: Function Annotation
comment: Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

SIP5F763D276430459D
type: Similarity Annotation
comment: Belongs to the TDE1 family.

PRO_0000342156
type: Chain Annotation
comment: Probable serine incorporator
mass: 52665
range: 18358912218117934tt1tt483

18358912218117934tt1
type: Position
type: ExactPosition
position: 1
reference: A9UY97-1

18358912218117934tt483
type: Position
type: ExactPosition
position: 483
reference: A9UY97-1

SIPF1193C1C05B9C660
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt43tt63

18358912218117934tt43
type: Position
type: ExactPosition
position: 43
reference: A9UY97-1

18358912218117934tt63
type: Position
type: ExactPosition
position: 63
reference: A9UY97-1

SIPD69F905F4068E3BC
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt109tt129

18358912218117934tt109
type: Position
type: ExactPosition
position: 109
reference: A9UY97-1

18358912218117934tt129
type: Position
type: ExactPosition
position: 129
reference: A9UY97-1

SIPE6A9A2B9F4507011
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt146tt166

18358912218117934tt146
type: Position
type: ExactPosition
position: 146
reference: A9UY97-1

18358912218117934tt166
type: Position
type: ExactPosition
position: 166
reference: A9UY97-1

SIP9CF6BCB5435341D2
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt169tt189

18358912218117934tt169
type: Position
type: ExactPosition
position: 169
reference: A9UY97-1

18358912218117934tt189
type: Position
type: ExactPosition
position: 189
reference: A9UY97-1

SIP8D59F63992DE6BF9
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt218tt238

18358912218117934tt218
type: Position
type: ExactPosition
position: 218
reference: A9UY97-1

18358912218117934tt238
type: Position
type: ExactPosition
position: 238
reference: A9UY97-1

SIP799A6C5E848F4364
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt249tt269

18358912218117934tt249
type: Position
type: ExactPosition
position: 249
reference: A9UY97-1

18358912218117934tt269
type: Position
type: ExactPosition
position: 269
reference: A9UY97-1

SIP488E275CBE545182
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt274tt294

18358912218117934tt274
type: Position
type: ExactPosition
position: 274
reference: A9UY97-1

18358912218117934tt294
type: Position
type: ExactPosition
position: 294
reference: A9UY97-1

SIP239B79B9777AE0C2
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt295tt315

18358912218117934tt295
type: Position
type: ExactPosition
position: 295
reference: A9UY97-1

18358912218117934tt315
type: Position
type: ExactPosition
position: 315
reference: A9UY97-1

SIP9CF1FDFD521BA28E
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt338tt358

18358912218117934tt338
type: Position
type: ExactPosition
position: 338
reference: A9UY97-1

18358912218117934tt358
type: Position
type: ExactPosition
position: 358
reference: A9UY97-1

SIP4C42BC9DBAFE85F6
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt414tt434

18358912218117934tt414
type: Position
type: ExactPosition
position: 414
reference: A9UY97-1

18358912218117934tt434
type: Position
type: ExactPosition
position: 434
reference: A9UY97-1

SIP83D4D8B1573E6E82
type: Transmembrane Annotation
comment: Helical
range: 18358912218117934tt457tt477

18358912218117934tt457
type: Position
type: ExactPosition
position: 457
reference: A9UY97-1

18358912218117934tt477
type: Position
type: ExactPosition
position: 477
reference: A9UY97-1

A9UY97-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 52665
value: MGLVASCFGGLAAYAAESVACCCGSAACSLCCRSCPSCTNSTSTRITYAILFFLSSIAAWIMLDKDVSKGLMKVCCYHSTLFRLVLFTQPAIKTTTNVVPWGELGVMRIMFSVCLFHLFLSLCTIGVSSSKDPRSSLHNGMWFIKLILLVGAMVGSFFISNSFFIGASWSWIGLVGAVLFMIVQFILLVDFAYSWNDSWVGKLEEGSKCAGFGSYRLISATVMLMAFVITLTVLMFHFYTNGDCKLSNFFIGFNLALALLVTLTSMLPSVREALPSSGILQSSVVAAYATYLVWSAVSGVPSTCHPLIAVAPLFLSSRGFLPPLPYVALKPAECGGDAGTNTAAIVIGALLTFISVAYSSIRTSSKSQLGKLGLQQGSNENIYLMDDKAADFDEDDEDRRLQRVVDNEQDAVRYSWSFFHLTFAVAALYLMMVLTEWDSSDADVRIGKGWASVWVQVVSSWVIFLLYGWTMMAPVCLPDRDFS

http://purl.uniprot.org/uniprot/A9UY97#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UY97#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UY97#attribution-DC036A124EC8E88DF072B29F6D9BB9FE
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/A9UY97#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UVV1
type: Protein
reviewed: true
created: 2012-05-16
modified: 2023-05-03
version: 68
mnemonic: SIR4_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP291A9A6D54AE3999
alternative name: SIP8E137299D54C373C
enzyme: http://purl.uniprot.org/enzyme/2.3.1.286
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPC95B4E5EFA15033D
annotation: SIP78FE64DEAAEAD559
annotation: SIP7B06ED8EC2E5A774
annotation: SIP21B5A697D9D4A6F5
annotation: SIP87330BFABB3E459A
annotation: SIP0F25C192C8CAF401
annotation: PRO_0000417352
annotation: SIP9E41A7EFD8DF15B7
annotation: SIPBC93B28D83A9C9C6
annotation: SIP8087C5B0401A1217
annotation: SIP8A1051AACBA2D455
annotation: SIP29F941C96EAAD132
annotation: SIP42FB994B43FA2D3E
annotation: SIP84970C0F6929CC6A
annotation: SIP160FAE8F2057101D
annotation: SIPAD76103C28C73956
annotation: SIP53CF5183A4A06BC2
annotation: SIPE22ABFA13FC49FBF
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/496
classified with: http://purl.uniprot.org/keywords/520
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/808
classified with: http://purl.uniprot.org/keywords/809
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0005759
classified with: GO_0005634
classified with: GO_0070403
classified with: GO_0017136
classified with: GO_0016740
classified with: GO_0008270
classified with: GO_0006476
sequence: A9UVV1-1
proteome: Unassembled WGS sequence

A9UVV1-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG2683
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.30.1600.10
type: Resource
database: Gene3D
comment: SIR2/SIRT2 'Small Domain
signature sequence match: Gene3D 3.30.1600.10 match 1

http://purl.uniprot.org/gene3d/3.40.50.1220
type: Resource
database: Gene3D
comment: TPP-binding domain
signature sequence match: Gene3D 3.40.50.1220 match 1

MF_01967
type: Resource
database: HAMAP
comment: Sirtuin_ClassII
signature sequence match: HAMAP MF 01967 match 1

IPR029035
type: Resource
database: InterPro
comment: DHS-like_NAD/FAD-binding_dom

IPR003000
type: Resource
database: InterPro
comment: Sirtuin

IPR026591
type: Resource
database: InterPro
comment: Sirtuin_cat_small_dom_sf

IPR026587
type: Resource
database: InterPro
comment: Sirtuin_class_II

IPR026590
type: Resource
database: InterPro
comment: Ssirtuin_cat_dom

PTHR47651
type: Resource
database: PANTHER
comment: NAD-DEPENDENT HISTONE DEACETYLASE HST4
signature sequence match: PANTHER PTHR47651 match 1

PTHR47651:SF7
type: Resource
database: PANTHER
comment: NAD-DEPENDENT PROTEIN DEACYLASE SIR-2.2
signature sequence match: PANTHER PTHR47651:SF7 match 1

PF02146
type: Resource
database: Pfam
comment: SIR2
signature sequence match: Pfam PF02146 match 1

SSF52467
type: Resource
database: SUPFAM
comment: DHS-like NAD/FAD-binding domain
signature sequence match: SUPFAM SSF52467 match 1

PS50305
type: Resource
database: PROSITE
comment: SIRTUIN
signature sequence match: PROSITE PS50305 match 1

SIP291A9A6D54AE3999
type: Structured Name
full name: NAD-dependent protein deacylase SIR4
ec name: 2.3.1.286

SIP8E137299D54C373C
type: Structured Name
full name: Regulatory protein SIR2 homolog 4

http://purl.uniprot.org/uniprot/A9UVV1#gene-MD5B05FDD1A63D51A51F9039455EB04B5AE
type: Gene
orf name: 15984

SIPC95B4E5EFA15033D
type: Function Annotation
comment: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

SIP7B06ED8EC2E5A774
type: Cofactor Annotation
comment: Binds 1 zinc ion per subunit.
cofactor: CHEBI_29105

SIP87330BFABB3E459A
type: Similarity Annotation
comment: Belongs to the sirtuin family. Class II subfamily.

SIP0F25C192C8CAF401
type: Transit Peptide Annotation
comment: Mitochondrion
range: 18358912169685294tt1tt16

18358912169685294tt1
type: Position
type: ExactPosition
position: 1
reference: A9UVV1-1

18358912169685294tt16
type: Position
type: ExactPosition
position: 16
reference: A9UVV1-1

PRO_0000417352
type: Chain Annotation
comment: NAD-dependent protein deacylase SIR4
mass: 31863
range: 18358912169685294tt17tt308

18358912169685294tt17
type: Position
type: ExactPosition
position: 17
reference: A9UVV1-1

18358912169685294tt308
type: Position
type: ExactPosition
position: 308
reference: A9UVV1-1

SIP9E41A7EFD8DF15B7
type: Domain Extent Annotation
comment: Deacetylase sirtuin-type
range: 18358912169685294tt28tt308

18358912169685294tt28
type: Position
type: ExactPosition
position: 28
reference: A9UVV1-1

SIPBC93B28D83A9C9C6
type: Active Site Annotation
comment: Proton acceptor
range: 18358912169685294tt147tt147

18358912169685294tt147
type: Position
type: ExactPosition
position: 147
reference: A9UVV1-1

18358912169685294tt53
type: Position
type: ExactPosition
position: 53
reference: A9UVV1-1

18358912169685294tt73
type: Position
type: ExactPosition
position: 73
reference: A9UVV1-1

18358912169685294tt129
type: Position
type: ExactPosition
position: 129
reference: A9UVV1-1

18358912169685294tt132
type: Position
type: ExactPosition
position: 132
reference: A9UVV1-1

18358912169685294tt155
type: Position
type: ExactPosition
position: 155
reference: A9UVV1-1

18358912169685294tt158
type: Position
type: ExactPosition
position: 158
reference: A9UVV1-1

18358912169685294tt211
type: Position
type: ExactPosition
position: 211
reference: A9UVV1-1

18358912169685294tt214
type: Position
type: ExactPosition
position: 214
reference: A9UVV1-1

18358912169685294tt251
type: Position
type: ExactPosition
position: 251
reference: A9UVV1-1

18358912169685294tt253
type: Position
type: ExactPosition
position: 253
reference: A9UVV1-1

18358912169685294tt277
type: Position
type: ExactPosition
position: 277
reference: A9UVV1-1

18358912169685294tt279
type: Position
type: ExactPosition
position: 279
reference: A9UVV1-1

18358912169685294tt297
type: Position
type: ExactPosition
position: 297
reference: A9UVV1-1

A9UVV1-1
type: Simple Sequence
modified: 2008-02-05
version: 1
precursor: true
mass: 33579
value: MAATKLHPALRNAIRAGANLPTEVISATFDVQEGIKLLSAFLLRHEPVCVLTGAGISTDSGIPDYRSPGRPPHRPLQHLEFLGSHERQQRYWARSLYGYPRIRDTMPNVGHQAINELQRRGLVGAIITQNVDGLHQRAGSQHVIDLHGRLDQVKCMNCHSITTRDELQSRLLADNKALLDQFSVVHDEAVRPDGDAVLDEDLYGRFTVAACASCGGVLKPNVVFFGGSLDPEDVKRASTAVSEASALFVVGTSLATWSAFRIVRQAVEEAKPVCVLNSGPTRADGVIPEYLRLCMPIGEVLPAALRQL

http://purl.uniprot.org/uniprot/A9UVV1#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UVV1#attribution-FAB84BD326A571B6E342F147F6C46FF0
manual: true
evidence: ECO_0000255
source: MF_03161

http://purl.uniprot.org/uniprot/A9UVV1#attribution-DA182776CF712B0F653704F43A901FBB
manual: true
evidence: ECO_0000255
source: PRU00236

A9V196
type: Protein
reviewed: true
created: 2009-09-22
modified: 2023-05-03
version: 54
mnemonic: SLX1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP277DE70CE7FB5885
enzyme: http://purl.uniprot.org/enzyme/3.1.-.-
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP49C576BC79C3C6BA
annotation: SIPF2D2E3470D53A922
annotation: SIPB094B6DCA6DFF0A2
annotation: SIPF22667536FC00789
annotation: SIP2BA7255B08E9D29C
annotation: PRO_0000383765
annotation: SIPD3E85AA0D1FEA7A3
annotation: SIP45ACC607AE3BEF72
annotation: SIP36A09536135F0365
annotation: SIPF73504068EAD7AA5
annotation: SIPDD5E166F2A45372E
annotation: SIP74B236BCC047C664
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/233
classified with: http://purl.uniprot.org/keywords/234
classified with: http://purl.uniprot.org/keywords/255
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/863
classified with: GO_0033557
classified with: GO_0017108
classified with: GO_0008821
classified with: GO_0046872
classified with: GO_0000724
sequence: A9V196-1
proteome: Unassembled WGS sequence

A9V196-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3005
type: Resource
database: eggNOG
comment: Eukaryota

cd10455
type: Resource
database: CDD
comment: GIY-YIG_SLX1
signature sequence match: CDD cd10455 match 1

http://purl.uniprot.org/gene3d/3.40.1440.10
type: Resource
database: Gene3D
comment: GIY-YIG endonuclease
signature sequence match: Gene3D 3.40.1440.10 match 1

http://purl.uniprot.org/gene3d/3.30.40.10
type: Resource
database: Gene3D
comment: Zinc/RING finger domain, C3HC4 (zinc finger)
signature sequence match: Gene3D 3.30.40.10 match 1

MF_03100
type: Resource
database: HAMAP
comment: Endonuc_su_Slx1
signature sequence match: HAMAP MF 03100 match 1

IPR000305
type: Resource
database: InterPro
comment: GIY-YIG_endonuc

IPR035901
type: Resource
database: InterPro
comment: GIY-YIG_endonuc_sf

IPR027520
type: Resource
database: InterPro
comment: Slx1

IPR013083
type: Resource
database: InterPro
comment: Znf_RING/FYVE/PHD

PTHR20208
type: Resource
database: PANTHER
comment: STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1
signature sequence match: PANTHER PTHR20208 match 1

PTHR20208:SF10
type: Resource
database: PANTHER
comment: STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1
signature sequence match: PANTHER PTHR20208:SF10 match 1

PF01541
type: Resource
database: Pfam
comment: GIY-YIG
signature sequence match: Pfam PF01541 match 1

PS50164
type: Resource
database: PROSITE
comment: GIY_YIG
signature sequence match: PROSITE PS50164 match 1

SIP277DE70CE7FB5885
type: Structured Name
full name: Structure-specific endonuclease subunit SLX1 homolog
ec name: 3.1.-.-

http://purl.uniprot.org/uniprot/A9V196#gene-MD5A027455F5828071997373B9CA13DAACD
type: Gene
orf name: 8836

SIP49C576BC79C3C6BA
type: Function Annotation
comment: Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

SIPB094B6DCA6DFF0A2
type: Subunit Annotation
comment: Forms a heterodimer with a member of the SLX4 family.

SIP2BA7255B08E9D29C
type: Similarity Annotation
comment: Belongs to the SLX1 family.

PRO_0000383765
type: Chain Annotation
comment: Structure-specific endonuclease subunit SLX1 homolog
mass: 45633
range: 18358915841996334tt1tt420

18358915841996334tt1
type: Position
type: ExactPosition
position: 1
reference: A9V196-1

18358915841996334tt420
type: Position
type: ExactPosition
position: 420
reference: A9V196-1

SIPD3E85AA0D1FEA7A3
type: Domain Extent Annotation
comment: GIY-YIG
range: 18358915841996334tt19tt106

18358915841996334tt19
type: Position
type: ExactPosition
position: 19
reference: A9V196-1

18358915841996334tt106
type: Position
type: ExactPosition
position: 106
reference: A9V196-1

SIP45ACC607AE3BEF72
type: Zinc Finger Annotation
comment: SLX1-type
range: 18358915841996334tt348tt405

18358915841996334tt348
type: Position
type: ExactPosition
position: 348
reference: A9V196-1

18358915841996334tt405
type: Position
type: ExactPosition
position: 405
reference: A9V196-1

SIP36A09536135F0365
type: Region Annotation
comment: Disordered
range: 18358915841996334tt237tt306

18358915841996334tt237
type: Position
type: ExactPosition
position: 237
reference: A9V196-1

18358915841996334tt306
type: Position
type: ExactPosition
position: 306
reference: A9V196-1

SIPF73504068EAD7AA5
type: Region Annotation
comment: Disordered
range: 18358915841996334tt311tt330

18358915841996334tt311
type: Position
type: ExactPosition
position: 311
reference: A9V196-1

18358915841996334tt330
type: Position
type: ExactPosition
position: 330
reference: A9V196-1

SIPDD5E166F2A45372E
type: Compositional Bias Annotation
comment: Polar residues
range: 18358915841996334tt248tt270

18358915841996334tt248
type: Position
type: ExactPosition
position: 248
reference: A9V196-1

18358915841996334tt270
type: Position
type: ExactPosition
position: 270
reference: A9V196-1

SIP74B236BCC047C664
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358915841996334tt279tt297

18358915841996334tt279
type: Position
type: ExactPosition
position: 279
reference: A9V196-1

18358915841996334tt297
type: Position
type: ExactPosition
position: 297
reference: A9V196-1

A9V196-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 45633
value: MAGGYIARVNMKGHYLSWSSDNTYPWQNIQPTQNTKLLGLQDIGFTTDPVRRLRQHNSEIGGGAVRTTRAKGSWDMAAIVYGFPNKVAALRFEWAWQHPLKSRRLRDAVRSDLPASRAAQMQLTAKLHTLAAMLYTVPWSDQPLTLCWLQPDIADKWSNIWQRHCQCQSALPPFLTTRSGNLQDPLFQLNNAAAAASTIQRAALAADHHAWRLAAAAQAQAPDFFTGLGRLDLAAPSVEESGAGPHPSSCSVPPSTGSSAAPTPGALAPQPTKQNKFGVDPRLDSDDRDDNHQFESPDNHEAAAVNVDVVDDSADDGTTDGNEDGPDDVAPHQEVTARHVHGAIGETCGHCHQSVYQELCIVCLNATCTYRAHLLCAAQAAVHPLGQSSPSETRLVPLRHSCPRCAHQAHWASWIAEVTL

http://purl.uniprot.org/uniprot/A9V196#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9V196#attribution-F0BDAEF05A91830374D2FB15AA7FEC56
manual: true
evidence: ECO_0000255
source: MF_03100

A9UWF0
type: Protein
reviewed: true
created: 2008-07-22
modified: 2023-06-28
version: 49
mnemonic: SURF1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP207A9394B746CB8C
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIP54E1E2BC8D8AF3BC
annotation: SIP56DA93C9E6913864
annotation: SIP157E4779A7C23941
annotation: PRO_0000344500
annotation: SIPD24464DFBA89EC49
annotation: SIP966FCDA47D4FCF27
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/999
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/1133
classified with: GO_0005743
classified with: GO_0005739
classified with: GO_0033617
sequence: A9UWF0-1
proteome: Unassembled WGS sequence

A9UWF0-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG1563
type: Resource
database: eggNOG
comment: Eukaryota

cd06662
type: Resource
database: CDD
comment: SURF1
signature sequence match: CDD cd06662 match 1

IPR002994
type: Resource
database: InterPro
comment: Surf1/Shy1

IPR045214
type: Resource
database: InterPro
comment: Surf1/Surf4

PTHR23427
type: Resource
database: PANTHER
comment: SURFEIT LOCUS PROTEIN
signature sequence match: PANTHER PTHR23427 match 1

PTHR23427:SF2
type: Resource
database: PANTHER
comment: SURFEIT LOCUS PROTEIN 1
signature sequence match: PANTHER PTHR23427:SF2 match 1

PF02104
type: Resource
database: Pfam
comment: SURF1
signature sequence match: Pfam PF02104 match 1

PS50895
type: Resource
database: PROSITE
comment: SURF1
signature sequence match: PROSITE PS50895 match 1

SIP207A9394B746CB8C
type: Structured Name
full name: SURF1-like protein

http://purl.uniprot.org/uniprot/A9UWF0#gene-MD5170E1EAD1D439C65D0DEAA10D14085E3
type: Gene
orf name: 18583

SIP54E1E2BC8D8AF3BC
type: Function Annotation
comment: Probably involved in the biogenesis of the COX complex.

SIP157E4779A7C23941
type: Similarity Annotation
comment: Belongs to the SURF1 family.

PRO_0000344500
type: Chain Annotation
comment: SURF1-like protein
mass: 28531
range: 18358912185413678tt1tt261

18358912185413678tt1
type: Position
type: ExactPosition
position: 1
reference: A9UWF0-1

18358912185413678tt261
type: Position
type: ExactPosition
position: 261
reference: A9UWF0-1

SIPD24464DFBA89EC49
type: Transmembrane Annotation
comment: Helical
range: 18358912185413678tt17tt37

18358912185413678tt17
type: Position
type: ExactPosition
position: 17
reference: A9UWF0-1

18358912185413678tt37
type: Position
type: ExactPosition
position: 37
reference: A9UWF0-1

SIP966FCDA47D4FCF27
type: Transmembrane Annotation
comment: Helical
range: 18358912185413678tt223tt243

18358912185413678tt223
type: Position
type: ExactPosition
position: 223
reference: A9UWF0-1

18358912185413678tt243
type: Position
type: ExactPosition
position: 243
reference: A9UWF0-1

A9UWF0-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 28531
value: MATSSSVAAASKRGGGLYWALLSVPVVTFGLGTWQIFRKQQKEELIATLEAKLSKEPAALPTNPADLAHMEYERVAVTGTFLHDQEMLVGPRTVTREVFSGMADLPEAGVQVITPFRLADTGEVILVNRGFVPEAQAPPHKRAAGQVEGTVRLEGIVRHGESQTAFVPDNHPEQNTWYWIDVFTMASNRSALPVLIDATAECTPPGGFPLGGQTNITVRNEHLSYIITWYSISAITLAMWVFLRRKGGNRSGLRAPPPRRT

http://purl.uniprot.org/uniprot/A9UWF0#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UWF0#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UWF0#attribution-DC036A124EC8E88DF072B29F6D9BB9FE
manual: true
evidence: ECO_0000255

http://purl.uniprot.org/uniprot/A9UWF0#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UYK7
type: Protein
reviewed: true
created: 2009-07-07
modified: 2023-02-22
version: 31
mnemonic: U518_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP7526FC4EC769AE32
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPE69F930DE38A1587
annotation: PRO_0000379017
annotation: SIPAEE0B48845EF5C96
annotation: SIP8ACDD48698079E8C
annotation: SIP4A7475104F2DBE0D
annotation: SIP402FB1A2E4AC6A41
annotation: SIP078DD71F393A98D4
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
sequence: A9UYK7-1
proteome: Unassembled WGS sequence

A9UYK7-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3695
type: Resource
database: eggNOG
comment: Eukaryota

IPR019384
type: Resource
database: InterPro
comment: FHIP

IPR045669
type: Resource
database: InterPro
comment: FHIP_C

IPR045668
type: Resource
database: InterPro
comment: FHIP_KELAA_motif

PTHR21705:SF11
type: Resource
database: PANTHER
comment: FHIP FAMILY PROTEIN CG3558
signature sequence match: PANTHER PTHR21705:SF11 match 1

PTHR21705
type: Resource
database: PANTHER
comment: RAI16 PROTEIN-RELATED
signature sequence match: PANTHER PTHR21705 match 1

PF19314
type: Resource
database: Pfam
comment: DUF5917
signature sequence match: Pfam PF19314 match 1

PF19311
type: Resource
database: Pfam
comment: KELAA
signature sequence match: Pfam PF19311 match 1

PF10257
type: Resource
database: Pfam
comment: RAI16-like
signature sequence match: Pfam PF10257 match 1

SIP7526FC4EC769AE32
type: Structured Name
full name: FHIP family protein 36947

http://purl.uniprot.org/uniprot/A9UYK7#gene-MD50A54B6226F3005E98B9BFC6FAD7A8B12
type: Gene
orf name: 36947

SIPE69F930DE38A1587
type: Similarity Annotation
comment: Belongs to the FHIP family.

PRO_0000379017
type: Chain Annotation
comment: FHIP family protein 36947
mass: 94995
range: 18358912219297582tt1tt880

18358912219297582tt1
type: Position
type: ExactPosition
position: 1
reference: A9UYK7-1

18358912219297582tt880
type: Position
type: ExactPosition
position: 880
reference: A9UYK7-1

SIPAEE0B48845EF5C96
type: Region Annotation
comment: Disordered
range: 18358912219297582tt437tt471

18358912219297582tt437
type: Position
type: ExactPosition
position: 437
reference: A9UYK7-1

18358912219297582tt471
type: Position
type: ExactPosition
position: 471
reference: A9UYK7-1

SIP8ACDD48698079E8C
type: Region Annotation
comment: Disordered
range: 18358912219297582tt677tt805

18358912219297582tt677
type: Position
type: ExactPosition
position: 677
reference: A9UYK7-1

18358912219297582tt805
type: Position
type: ExactPosition
position: 805
reference: A9UYK7-1

SIP4A7475104F2DBE0D
type: Compositional Bias Annotation
comment: Polar residues
range: 18358912219297582tt442tt471

18358912219297582tt442
type: Position
type: ExactPosition
position: 442
reference: A9UYK7-1

SIP402FB1A2E4AC6A41
type: Compositional Bias Annotation
comment: Basic and acidic residues
range: 18358912219297582tt746tt762

18358912219297582tt746
type: Position
type: ExactPosition
position: 746
reference: A9UYK7-1

18358912219297582tt762
type: Position
type: ExactPosition
position: 762
reference: A9UYK7-1

SIP078DD71F393A98D4
type: Compositional Bias Annotation
comment: Polar residues
range: 18358912219297582tt763tt805

18358912219297582tt763
type: Position
type: ExactPosition
position: 763
reference: A9UYK7-1

A9UYK7-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 94995
value: MAGLMSRLRAARGGDGPSGAQLHSEAGRAALFDTALSKLYKTIDQMQTKRVHLFNPIKTAEEQLQQIYLVLEAEEASIHDGMTGACLQYLLTSQRLHNIAKGLLGDQPLGARLVWLSFILQVLSHLKHPLLIHAEVLEALNSTIKVLRRDQRRLALAEANIYMQLLLRLTEYLERNPSCLPLFLEEKPQPAFPLLAALMPFVQHHTDEGKLARKAVVTCCQLANHSQQLEQFLLRHEIFAAEVAGALAGAYSNLPMSLPARSRKALKAWAYGAKAFSHRVPRAAHYFNALTFCGQVVRAVPSSVRGLILDQVYHGFMLSVLLPSLHHRAPEEAVAAMNYLRISLSRTRNTPLQGAFLRLLLASQFEGCWTLDRLVERLETLGEQSLTALSLFQALIRLHNEDVLLRLCLRFVHRPLARAAAAASRPPYPGTLMPADSGCNSEPESDIGTGTSTNTGAANHTGAGTDTSTSVHADKSNRVQLQGGTHPNGSSDVSAFALHNALEMRAGRKLLQLVPAQTAISPSERTFEGYLHAASQGVDAACAACATWRLSYLQLRPHQWLGKEDLDIDAATVNDNASAVSRCESEGLFLATLSRLTRRMLEHNLATNLLLSSIVSMLASLPVPALRNYLLDLNSPSIEGISFVEQLHALREDCLRLLAEDEGLEANLHAYRAGAEGYSRPKHRVKAPSTTAPASPARGPLATFHSSRRSRDRAASIVALPPHSAANEPGGVSTSAPTPASRASDADGASRRDARPEEPTIDDEAATTSNGGFDDGTSEQDSDSVCSSYSGSSSHRASAVSASHPSTRLTAAALATLDQERPPLPSPALGATTDTAPSVSAVGDEIKDSKRRALKVLIVQEFVKELAACAMEQSLLAVAM

http://purl.uniprot.org/uniprot/A9UYK7#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UR29
type: Protein
reviewed: true
created: 2010-03-02
modified: 2023-02-22
version: 48
mnemonic: UFC1_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP8F03E3E6D751C7DB
alternative name: SIP5EF66F31E70FC7DE
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPD968E7112BB273EB
annotation: SIPC10115F7D0D8E3F6
annotation: PRO_0000391979
annotation: SIPA0AB1A5417AA0FBB
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/833
classified with: GO_0061657
classified with: GO_0071568
classified with: GO_1990592
sequence: MVDAHTRKTLAAIPLLRVNAGPRSGDLWRARHKEELMSLITYVKNNKENDNDWFRLESNPEGTRWFGKCWIVVDMLKYEFDLEFDIPVAYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPHFGIAHAMALGLGPWLAVEIPDLVSKGIVKHKETSS
proteome: Unassembled WGS sequence

A9UR29-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG3357
type: Resource
database: eggNOG
comment: Eukaryota

http://purl.uniprot.org/gene3d/3.10.110.10
type: Resource
database: Gene3D
comment: Ubiquitin Conjugating Enzyme
signature sequence match: Gene3D 3.10.110.10 match 1

IPR016135
type: Resource
database: InterPro
comment: UBQ-conjugating_enzyme/RWD

IPR014806
type: Resource
database: InterPro
comment: Ufc1

PTHR12921
type: Resource
database: PANTHER
comment: UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1
signature sequence match: PANTHER PTHR12921 match 1

PTHR12921:SF0
type: Resource
database: PANTHER
comment: UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1
signature sequence match: PANTHER PTHR12921:SF0 match 1

PF08694
type: Resource
database: Pfam
comment: UFC1
signature sequence match: Pfam PF08694 match 1

PIRSF008716
type: Resource
database: PIRSF
comment: DUF1782
signature sequence match: PIRSF PIRSF008716 match 1

SSF54495
type: Resource
database: SUPFAM
comment: UBC-like
signature sequence match: SUPFAM SSF54495 match 1

SIP8F03E3E6D751C7DB
type: Structured Name
full name: Ubiquitin-fold modifier-conjugating enzyme 1

SIP5EF66F31E70FC7DE
type: Structured Name
full name: Ufm1-conjugating enzyme 1

http://purl.uniprot.org/uniprot/A9UR29#gene-MD5BED9C4FCE4775C33A15234801CE8A58D
type: Gene
orf name: 21173

SIPD968E7112BB273EB
type: Function Annotation
comment: E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

SIPC10115F7D0D8E3F6
type: Similarity Annotation
comment: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.

PRO_0000391979
type: Chain Annotation
comment: Ubiquitin-fold modifier-conjugating enzyme 1
mass: 18841
range: 18358912100219182tt1tt166

18358912100219182tt1
type: Position
type: ExactPosition
position: 1
reference: MVDAHTRKTLAAIPLLRVNAGPRSGDLWRARHKEELMSLITYVKNNKENDNDWFRLESNPEGTRWFGKCWIVVDMLKYEFDLEFDIPVAYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPHFGIAHAMALGLGPWLAVEIPDLVSKGIVKHKETSS

18358912100219182tt166
type: Position
type: ExactPosition
position: 166
reference: MVDAHTRKTLAAIPLLRVNAGPRSGDLWRARHKEELMSLITYVKNNKENDNDWFRLESNPEGTRWFGKCWIVVDMLKYEFDLEFDIPVAYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPHFGIAHAMALGLGPWLAVEIPDLVSKGIVKHKETSS

SIPA0AB1A5417AA0FBB
type: Active Site Annotation
comment: Glycyl thioester intermediate
range: 18358912100219182tt116tt116

18358912100219182tt116
type: Position
type: ExactPosition
position: 116
reference: MVDAHTRKTLAAIPLLRVNAGPRSGDLWRARHKEELMSLITYVKNNKENDNDWFRLESNPEGTRWFGKCWIVVDMLKYEFDLEFDIPVAYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPHFGIAHAMALGLGPWLAVEIPDLVSKGIVKHKETSS

MVDAHTRKTLAAIPLLRVNAGPRSGDLWRARHKEELMSLITYVKNNKENDNDWFRLESNPEGTRWFGKCWIVVDMLKYEFDLEFDIPVAYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPHFGIAHAMALGLGPWLAVEIPDLVSKGIVKHKETSS
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 18841

http://purl.uniprot.org/uniprot/A9UR29#attribution-4D7F72A356C1855D0A9FA246AE0C711F
creator: GO Central
manual: true
evidence: ECO_0000318
source: http://purl.uniprot.org/citations/21873635

http://purl.uniprot.org/uniprot/A9UR29#attribution-609619A7DF3E53CE5E48EDEF8B8F9DD1
manual: true
evidence: ECO_0000250

http://purl.uniprot.org/uniprot/A9UR29#attribution-080ED3982FEC43F7C43A0689717F3D20
manual: true
evidence: ECO_0000305

A9UP22
type: Protein
reviewed: true
created: 2009-04-14
modified: 2023-05-03
version: 67
mnemonic: WDR12_MONBE
citation: http://purl.uniprot.org/citations/18273011
recommended name: SIP0C806052F8B1AA8E
organism: http://purl.uniprot.org/taxonomy/81824
annotation: SIPBC86AC14483E8D88
annotation: SIPB8DF587D2FA78E02
annotation: SIP3CFC60453F8F3098
annotation: PRO_0000369570
annotation: SIP9243DCF576BE81F4
annotation: SIPE7F5D26E08A4B65F
annotation: SIPB233756232946494
annotation: SIP63CC946D79CDE8A6
annotation: SIPD72C8EF377207E83
annotation: SIPA8A59C89483C0C7F
annotation: SIP394AC9B17F5CC7FA
annotation: SIPD5B10200A77F4372
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/1185
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/690
classified with: http://purl.uniprot.org/keywords/698
classified with: http://purl.uniprot.org/keywords/853
classified with: GO_0005730
classified with: GO_0005654
classified with: GO_0030687
classified with: GO_0043021
classified with: GO_0000466
classified with: GO_0000463
sequence: A9UP22-1
proteome: Unassembled WGS sequence

A9UP22-citation-18273011
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

MX1 / ATCC 50154
type: Strain

KOG0313
type: Resource
database: eggNOG
comment: Eukaryota

MF_03029
type: Resource
database: HAMAP
comment: WDR12
signature sequence match: HAMAP MF 03029 match 1

IPR012972
type: Resource
database: InterPro
comment: NLE

IPR028599
type: Resource
database: InterPro
comment: WDR12/Ytm1

PTHR19855:SF11
type: Resource
database: PANTHER
comment: RIBOSOME BIOGENESIS PROTEIN WDR12
signature sequence match: PANTHER PTHR19855:SF11 match 1

PTHR19855
type: Resource
database: PANTHER
comment: WD40 REPEAT PROTEIN 12, 37
signature sequence match: PANTHER PTHR19855 match 1

PF08154
type: Resource
database: Pfam
comment: NLE
signature sequence match: Pfam PF08154 match 1

SIP0C806052F8B1AA8E
type: Structured Name
full name: Ribosome biogenesis protein WDR12 homolog

http://purl.uniprot.org/uniprot/A9UP22#gene-MD56FB3C73B83567318E8FE1ACCABDDB858
type: Gene
orf name: 30764

SIPBC86AC14483E8D88
type: Function Annotation
comment: Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

SIP3CFC60453F8F3098
type: Similarity Annotation
comment: Belongs to the WD repeat WDR12/YTM1 family.

PRO_0000369570
type: Chain Annotation
comment: Ribosome biogenesis protein WDR12 homolog
mass: 48702
range: 18358912066662958tt1tt447

18358912066662958tt1
type: Position
type: ExactPosition
position: 1
reference: A9UP22-1

18358912066662958tt447
type: Position
type: ExactPosition
position: 447
reference: A9UP22-1

SIP9243DCF576BE81F4
type: Repeat Annotation
comment: WD 1
range: 18358912066662958tt107tt147

18358912066662958tt107
type: Position
type: ExactPosition
position: 107
reference: A9UP22-1

18358912066662958tt147
type: Position
type: ExactPosition
position: 147
reference: A9UP22-1

SIPE7F5D26E08A4B65F
type: Repeat Annotation
comment: WD 2
range: 18358912066662958tt148tt191

18358912066662958tt148
type: Position
type: ExactPosition
position: 148
reference: A9UP22-1

18358912066662958tt191
type: Position
type: ExactPosition
position: 191
reference: A9UP22-1

SIPB233756232946494
type: Repeat Annotation
comment: WD 3
range: 18358912066662958tt195tt234

18358912066662958tt195
type: Position
type: ExactPosition
position: 195
reference: A9UP22-1

18358912066662958tt234
type: Position
type: ExactPosition
position: 234
reference: A9UP22-1

SIP63CC946D79CDE8A6
type: Repeat Annotation
comment: WD 4
range: 18358912066662958tt262tt300

18358912066662958tt262
type: Position
type: ExactPosition
position: 262
reference: A9UP22-1

18358912066662958tt300
type: Position
type: ExactPosition
position: 300
reference: A9UP22-1

SIPD72C8EF377207E83
type: Repeat Annotation
comment: WD 5
range: 18358912066662958tt304tt344

18358912066662958tt304
type: Position
type: ExactPosition
position: 304
reference: A9UP22-1

18358912066662958tt344
type: Position
type: ExactPosition
position: 344
reference: A9UP22-1

SIPA8A59C89483C0C7F
type: Repeat Annotation
comment: WD 6
range: 18358912066662958tt350tt398

18358912066662958tt350
type: Position
type: ExactPosition
position: 350
reference: A9UP22-1

18358912066662958tt398
type: Position
type: ExactPosition
position: 398
reference: A9UP22-1

SIP394AC9B17F5CC7FA
type: Repeat Annotation
comment: WD 7
range: 18358912066662958tt414tt447

18358912066662958tt414
type: Position
type: ExactPosition
position: 414
reference: A9UP22-1

SIPD5B10200A77F4372
type: Region Annotation
comment: Ubiquitin-like (UBL) domain
range: 18358912066662958tt11tt92

18358912066662958tt11
type: Position
type: ExactPosition
position: 11
reference: A9UP22-1

18358912066662958tt92
type: Position
type: ExactPosition
position: 92
reference: A9UP22-1

A9UP22-1
type: Simple Sequence
modified: 2008-02-05
version: 1
mass: 48702
value: MASADETGQELRISLFTTLPKRYVVTSAPIAVPANLRRRGLSSLINSMLDLDPPKPFDFLIEHEYLRSSLLDHVLQSQKDGAEAIIKVEYTLAMPPPQPGPSMPHEDWVGGLASTSVNGQEWLATASYDHHGRLWLPKRTECERVLQGHTRPVLGVDFITTDHSESVDVATGGMDQAVRIWQHRETESRVLVGLGHRGTVQCVAAQPTGNIVASGSWDHEIFLWSCVPDADDLDSAPGNKRRKVDSLYNEVQLKAPLGHLHGSGSVVHDMAWASVDTLYSVGGDHAVRQWDVEAGKLKMTQVGAKTGHGVAVHQGNAEHLTVATADVDGAARLYDFRTAGGTSGTTVLRSFTGPAHAVAFNPTNAYQVAVCGDEAIVNLEMAYPIKIWDRRSTRMPLHNLRVPAAEVPRGTERVDSYRMLALTWTPSALFAGGASKRVHAFHTESVQ

http://purl.uniprot.org/uniprot/A9UP22#attribution-CE4F36388C1426A9688D339E15245F35
manual: true
evidence: ECO_0000255
source: MF_03029