K4MSF5
type: Protein
reviewed: false
created: 2013-01-09
modified: 2023-09-13
version: 35
mnemonic: K4MSF5_9EUKA
citation: http://purl.uniprot.org/citations/23058793
recommended name: SIPAC6946E25126E43E
enzyme: http://purl.uniprot.org/enzyme/2.7.7.6
organism: http://purl.uniprot.org/taxonomy/1243177
annotation: SIPA07D3BC21E6E8ECC
annotation: SIPAEA3D37FE439AA50
annotation: SIP8B92F072F59B7C8E
annotation: SIP4F2E5D5CA7FD415A
annotation: SIP7E73C394EBB2BC0E
annotation: SIP805F4CAC7AA87CF4
annotation: SIP80DE169550C0F176
annotation: SIP2FC0870DD75AEEB4
annotation: SIP136BC1F91344F68E
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/240
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0000428
classified with: GO_0003677
classified with: GO_0003899
classified with: GO_0046872
classified with: GO_0032549
classified with: GO_0006351
sequence: K4MSF5-1

K4MSF5-citation-23058793
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd00653
type: Resource
database: CDD
comment: RNA_pol_B_RPB2
signature sequence match: CDD cd00653 match 1

http://purl.uniprot.org/gene3d/2.40.270.10
type: Resource
database: Gene3D
comment: DNA-directed RNA polymerase, subunit 2, domain 6
signature sequence match: Gene3D 2.40.270.10 match 1

http://purl.uniprot.org/gene3d/3.90.1800.10
type: Resource
database: Gene3D
comment: RNA polymerase alpha subunit dimerisation domain
signature sequence match: Gene3D 3.90.1800.10 match 1

http://purl.uniprot.org/gene3d/3.90.1110.10
type: Resource
database: Gene3D
comment: RNA polymerase Rpb2, domain 2
signature sequence match: Gene3D 3.90.1110.10 match 1

IPR015712
type: Resource
database: InterPro
comment: DNA-dir_RNA_pol_su2

IPR007120
type: Resource
database: InterPro
comment: DNA-dir_RNAP_su2_dom

IPR037033
type: Resource
database: InterPro
comment: DNA-dir_RNAP_su2_hyb_sf

IPR007644
type: Resource
database: InterPro
comment: RNA_pol_bsu_protrusion

IPR007642
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_2

IPR037034
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_2_sf

IPR007645
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_3

IPR007646
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_4

IPR007647
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_5

IPR007641
type: Resource
database: InterPro
comment: RNA_pol_Rpb2_7

IPR014724
type: Resource
database: InterPro
comment: RNA_pol_RPB2_OB-fold

PTHR20856
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2
signature sequence match: PANTHER PTHR20856 match 1

PTHR20856:SF7
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2
signature sequence match: PANTHER PTHR20856:SF7 match 1

PF04563
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_1
signature sequence match: Pfam PF04563 match 1

PF04561
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_2
signature sequence match: Pfam PF04561 match 1

PF04565
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_3
signature sequence match: Pfam PF04565 match 1

PF04566
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_4
signature sequence match: Pfam PF04566 match 1

PF04567
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_5
signature sequence match: Pfam PF04567 match 1

PF00562
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_6
signature sequence match: Pfam PF00562 match 1

PF04560
type: Resource
database: Pfam
comment: RNA_pol_Rpb2_7
signature sequence match: Pfam PF04560 match 1

SSF64484
type: Resource
database: SUPFAM
comment: beta and beta-prime subunits of DNA dependent RNA-polymerase
signature sequence match: SUPFAM SSF64484 match 1

SIPAC6946E25126E43E
type: Structured Name
full name: DNA-directed RNA polymerase
ec name: 2.7.7.6

RPB2
type: Gene

SIPAEA3D37FE439AA50
type: Similarity Annotation
comment: Belongs to the RNA polymerase beta chain family.

SIP8B92F072F59B7C8E
type: Domain Extent Annotation
comment: RNA polymerase beta subunit protrusion
range: 21168129967535406tt20tt439

21168129967535406tt20
type: Position
type: ExactPosition
position: 20
reference: K4MSF5-1

21168129967535406tt439
type: Position
type: ExactPosition
position: 439
reference: K4MSF5-1

SIP4F2E5D5CA7FD415A
type: Domain Extent Annotation
comment: RNA polymerase Rpb2
range: 21168129967535406tt200tt391

21168129967535406tt200
type: Position
type: ExactPosition
position: 200
reference: K4MSF5-1

21168129967535406tt391
type: Position
type: ExactPosition
position: 391
reference: K4MSF5-1

SIP7E73C394EBB2BC0E
type: Domain Extent Annotation
comment: RNA polymerase Rpb2
range: 21168129967535406tt465tt529

21168129967535406tt465
type: Position
type: ExactPosition
position: 465
reference: K4MSF5-1

21168129967535406tt529
type: Position
type: ExactPosition
position: 529
reference: K4MSF5-1

SIP805F4CAC7AA87CF4
type: Domain Extent Annotation
comment: RNA polymerase Rpb2
range: 21168129967535406tt564tt625

21168129967535406tt564
type: Position
type: ExactPosition
position: 564
reference: K4MSF5-1

21168129967535406tt625
type: Position
type: ExactPosition
position: 625
reference: K4MSF5-1

SIP80DE169550C0F176
type: Domain Extent Annotation
comment: RNA polymerase Rpb2
range: 21168129967535406tt646tt699

21168129967535406tt646
type: Position
type: ExactPosition
position: 646
reference: K4MSF5-1

21168129967535406tt699
type: Position
type: ExactPosition
position: 699
reference: K4MSF5-1

SIP2FC0870DD75AEEB4
type: Domain Extent Annotation
comment: DNA-directed RNA polymerase subunit 2 hybrid-binding
range: 21168129967535406tt707tt1078

21168129967535406tt707
type: Position
type: ExactPosition
position: 707
reference: K4MSF5-1

21168129967535406tt1078
type: Position
type: ExactPosition
position: 1078
reference: K4MSF5-1

SIP136BC1F91344F68E
type: Domain Extent Annotation
comment: RNA polymerase Rpb2
range: 21168129967535406tt1080tt1170

21168129967535406tt1080
type: Position
type: ExactPosition
position: 1080
reference: K4MSF5-1

21168129967535406tt1170
type: Position
type: ExactPosition
position: 1170
reference: K4MSF5-1

K4MSF5-1
type: Simple Sequence
modified: 2013-01-09
version: 1
mass: 132160
value: MDITQENCWQVISSFFEEKGLVRQQLDSFDSFIQNTMQELVDEHSQLVLQSNSQFSGQEGDVTRRHVIQFGQVYLSKPLHTEKDGMSTPLLPSMARLRNLTYAAPLYIDIKKTTYVADPNHELNQGIVNVNEMHLEQEDEVMYERIFLGKVPLMVKSSYCALSSSSNHELMGMGECPYDQGGYFIINGSEKVLIAQERMANNQVYVFAKSPPSPYSYTAEIRSAVERGGKNASAVFVKMLSRLADKGTSGQYIRCQIPYIKQDIPIGIVFRALGVVADKDILSHIVYDPEDTQMLDLLKPCIEEAFTIQDQNVALDFIGKRGTTVGVRREQRIKYAREILQKEFLPHVGVEEHSESKKAFFFGYMINRLLQCALERRELDDRDHFAKKRLDLAGPLLGGLFRMLFRKLTTDVGKYLQKCINEGREFNLPLAVKHQIITSGLKYSIATGNWGDQSKAMSTRAGVSQVLNRYTYISTLSHLRRCNAPIGREGKLAKPRQLHNSQFGMVCPAESPEGQACGLVKNLALMAYVSVGSPTSPVLEFLEEWAMENLADVNPSFIGGATKVFVNGVWVGIHRDPDMLAENLKQLRRSLDLSQEVSIVRDYRDRELRLYTDSGRVCRPLFIVKDGALVLTKNHVRLLEKKEIGWNQLLADGVVEYIDTEEEETALISMTPEDLVESKMRAMNGQPDLKKWTHCELHPSLMFGVSASTIPFPDHNQSPRNCYSASQSKQTIGVYLTNFQQRMDTLSSVLFYPQKPLVTTRAMEHLHYRELPAGQNAIVAIACHGGYNQEDSILMSQSAIDRGLFRSFFFRTYTEQVKKVGALELEEIEKPNPRDTLIRRGNNYEKLDADGLVPPGTRVSGDDILVGKTVPIPVDSEELGQRTARHVKRDSSATMRSTEYGVVDQVLLTTNDLDLKMCKTRVRSVKIPQVGDKHCSRHGQKGVLGMLYRQEDLPYTADGIVPDVIINPHAIPSRMTIGHLIECLLSKVSALTGDEGDGTPFTDVTVEDISNALAKCGYQKRGFEVLYNGQTGQKLAANIFIGPTFYQRLKHMVDDKIHARARGPVQILTRQPVEGRSRDGGLRFGEMEHDVIVAHGAAMFLKERLFDVSDAFRVHVCDLCGLMCIANLSKNSYECRICHNKTQISQIHLPYATKLLFQELMSMNIAPRIVVDEQ

K4N3B4
type: Protein
reviewed: false
created: 2013-01-09
modified: 2023-02-22
version: 35
mnemonic: K4N3B4_9EUKA
citation: http://purl.uniprot.org/citations/23058793
recommended name: SIP3A9FA4F947667D6C
enzyme: http://purl.uniprot.org/enzyme/2.7.7.6
organism: http://purl.uniprot.org/taxonomy/1243177
annotation: SIPC3A5F4D0BCE25CE8
annotation: SIP1CE29190E92E24A5
annotation: SIPA84C71355F791053
annotation: SIP142EB53A688B0160
annotation: SIP2B4A3AFD5FD44080
annotation: SIPBF8B100B0AF6088D
annotation: SIP76DB8D2F44292E47
annotation: SIPB6731BEB91F9F6E3
existence: Inferred from Homology Existence
classified with: http://purl.uniprot.org/keywords/238
classified with: http://purl.uniprot.org/keywords/240
classified with: http://purl.uniprot.org/keywords/460
classified with: http://purl.uniprot.org/keywords/479
classified with: http://purl.uniprot.org/keywords/548
classified with: http://purl.uniprot.org/keywords/539
classified with: http://purl.uniprot.org/keywords/597
classified with: http://purl.uniprot.org/keywords/677
classified with: http://purl.uniprot.org/keywords/862
classified with: GO_0000428
classified with: GO_0005634
classified with: GO_0003677
classified with: GO_0003899
classified with: GO_0046872
classified with: GO_0006366
sequence: K4N3B4-1

K4N3B4-citation-23058793
type: Citation Statement
scope: NUCLEOTIDE SEQUENCE

cd02584
type: Resource
database: CDD
comment: RNAP_II_Rpb1_C
signature sequence match: CDD cd02584 match 1

cd02733
type: Resource
database: CDD
comment: RNAP_II_RPB1_N
signature sequence match: CDD cd02733 match 1

http://purl.uniprot.org/gene3d/3.30.1490.180
type: Resource
database: Gene3D
comment: RNA polymerase ii
signature sequence match: Gene3D 3.30.1490.180 match 1

http://purl.uniprot.org/gene3d/4.10.860.120
type: Resource
database: Gene3D
comment: RNA polymerase II, clamp domain
signature sequence match: Gene3D 4.10.860.120 match 1

http://purl.uniprot.org/gene3d/1.10.274.100
type: Resource
database: Gene3D
comment: RNA polymerase Rpb1, domain 3
signature sequence match: Gene3D 1.10.274.100 match 1

IPR045867
type: Resource
database: InterPro
comment: DNA-dir_RpoC_beta_prime

IPR000722
type: Resource
database: InterPro
comment: RNA_pol_asu

IPR000684
type: Resource
database: InterPro
comment: RNA_pol_II_repeat_euk

IPR006592
type: Resource
database: InterPro
comment: RNA_pol_N

IPR007080
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_1

IPR007066
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_3

IPR042102
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_3_sf

IPR007083
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_4

IPR007081
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_5

IPR007075
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_6

IPR007073
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_7

IPR038593
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_7_sf

IPR044893
type: Resource
database: InterPro
comment: RNA_pol_Rpb1_clamp_domain

IPR038120
type: Resource
database: InterPro
comment: Rpb1_funnel_sf

PTHR19376
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE
signature sequence match: PANTHER PTHR19376 match 1

PTHR19376:SF37
type: Resource
database: PANTHER
comment: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
signature sequence match: PANTHER PTHR19376:SF37 match 1

PF04997
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_1
signature sequence match: Pfam PF04997 match 1

PF00623
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_2
signature sequence match: Pfam PF00623 match 1

PF04983
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_3
signature sequence match: Pfam PF04983 match 1

PF05000
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_4
signature sequence match: Pfam PF05000 match 1

PF04998
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_5
signature sequence match: Pfam PF04998 match 1

PF04992
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_6
signature sequence match: Pfam PF04992 match 1

PF04990
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_7
signature sequence match: Pfam PF04990 match 1

PF05001
type: Resource
database: Pfam
comment: RNA_pol_Rpb1_R
signature sequence match: Pfam PF05001 match 1
signature sequence match: Pfam PF05001 match 2
signature sequence match: Pfam PF05001 match 3
signature sequence match: Pfam PF05001 match 4
signature sequence match: Pfam PF05001 match 5
signature sequence match: Pfam PF05001 match 6
signature sequence match: Pfam PF05001 match 7
signature sequence match: Pfam PF05001 match 8
signature sequence match: Pfam PF05001 match 9
signature sequence match: Pfam PF05001 match 10
signature sequence match: Pfam PF05001 match 11
signature sequence match: Pfam PF05001 match 12
signature sequence match: Pfam PF05001 match 13
signature sequence match: Pfam PF05001 match 14

SM00663
type: Resource
database: SMART
comment: RPOLA_N
signature sequence match: SMART SM00663 match 1

PS00115
type: Resource
database: PROSITE
comment: RNA_POL_II_REPEAT
signature sequence match: PROSITE PS00115 match 1
signature sequence match: PROSITE PS00115 match 2
signature sequence match: PROSITE PS00115 match 3
signature sequence match: PROSITE PS00115 match 4
signature sequence match: PROSITE PS00115 match 5
signature sequence match: PROSITE PS00115 match 6
signature sequence match: PROSITE PS00115 match 7

SIP3A9FA4F947667D6C
type: Structured Name
full name: DNA-directed RNA polymerase subunit
ec name: 2.7.7.6

RPB1
type: Gene

SIPC3A5F4D0BCE25CE8
type: Function Annotation
comment: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

SIP142EB53A688B0160
type: Similarity Annotation
comment: Belongs to the RNA polymerase beta' chain family.

SIP2B4A3AFD5FD44080
type: Domain Extent Annotation
comment: RNA polymerase N-terminal
range: 21168133725369390tt239tt540

21168133725369390tt239
type: Position
type: ExactPosition
position: 239
reference: K4N3B4-1

21168133725369390tt540
type: Position
type: ExactPosition
position: 540
reference: K4N3B4-1

SIPBF8B100B0AF6088D
type: Region Annotation
comment: Disordered
range: 21168133725369390tt154tt177

21168133725369390tt154
type: Position
type: ExactPosition
position: 154
reference: K4N3B4-1

21168133725369390tt177
type: Position
type: ExactPosition
position: 177
reference: K4N3B4-1

SIP76DB8D2F44292E47
type: Region Annotation
comment: Disordered
range: 21168133725369390tt1551tt1767

21168133725369390tt1551
type: Position
type: ExactPosition
position: 1551
reference: K4N3B4-1

21168133725369390tt1767
type: Position
type: ExactPosition
position: 1767
reference: K4N3B4-1

SIPB6731BEB91F9F6E3
type: Compositional Bias Annotation
comment: Polar residues
range: 21168133725369390tt155tt175

21168133725369390tt155
type: Position
type: ExactPosition
position: 155
reference: K4N3B4-1

21168133725369390tt175
type: Position
type: ExactPosition
position: 175
reference: K4N3B4-1

K4N3B4-1
type: Simple Sequence
modified: 2013-01-09
version: 1
mass: 195557
value: MDNSSAPQRRVKQLQFGLLSPEEIKAWSVCRVDFPETYENGRPKLGGLLDPRMGTVDRNLKCLTCQESMNDCVGHFGHVELQRAVFHIGFMARIKKILECVCHSCAKLKVDTDNPRFLQTQFIKDPSKRLRAVWELCKGKQMCEGSVIEASGQKAATADDSQNVSSSSQKRSGCGAVQPSYKKEGLKFVATFKQQQQFEESAEPNKDIFNGHKVYNIFKRISDDDCRRLGLDPEWARPDWMLISVLPVPPPPVRPSIQVDGASRGEDDLTYKLADIIKANQNLKNHVDDSPAHIIAEYEALLQYHVVTYMNNDVSGIPQATQKSGRPIKSIRARLKGKEGRLRGNLMGKRVDFSARTVITGDPNISLDEVGVPRTIAKTLTFPEIVTPFNFQQLQEAVDNGPNEHPGARYVIRQNGDRIDLSRAGAIELQLNVGDKVERHIRDGDIVLFNRQPSLHKMSMMGHRVRVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSYETKAELSEICMVPRQIVSPQANRPVMGIVQDTLCGVRKFTKRDSFLTKEMVMSLCMWVRDWDGQLPQPAIIKPVPLWTGKQIFSLIIPPGTNMIGYHSQHPDNESSDISPGDTKVVIYDGELVCGIICKKTVGTSQNSLIHVIWKEHGPEKTRNFFDGCQAVVNNWLFSYGFSIGIGDTIADAQTMQVVATTISNAKNKVTEYISQAHRNVLQPSPGMTIQESFESRVNQELNRARDIAGASAQKSLNDANNVKQMVVAGSKGSFINISQMTACVGQQNVEGRRIPFGFKYRTLPHFTKDDQSPESRGFVENSYLRGLTPSELFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDVSVGYDCSVRNALGQVLQFAYGEDGMDGTSMERQTLDSLRLNEDKFKMKYKIDVSDSKYQLSPKTVKPEILQEMVQTPEIQLLLDEEFEQLSRDRALLRDHIFRKGDNQWPLPVNISRLIWNAQCIFKVKKNERSDLRPADIVRSVQELASKINIINTQDKCTAELKENASLLFRILLRSVLATKRILQEFHLTKAAFSWILGEIESKFHQSMVAPNEMVGTIAAQSIGEPATQMTLNTFHYAGVSSKNVTLGVPRLKEIINVARNNKTPSTTIYLKGDYAKLPQKAKEVQAAIEYTTLRKVADRTEIWYDPDIENTRIVEDEDTVLAYYSLMVDEDFSRYSPWVLRIVLDRRMMLDKETKPQLIVSRLKEEFQNDLDICSSDENAPVPVIRIRILRNEEDVDQDALDEEDTILRKLEAHILNQIPLRGIEGINRVFMVEKKNVALNDQGDYEQFSEWVLETDGINLKNVMTVDNVDAGRTYSNNIVEITETLGIEAGRAALLKELRNVIEFDGSYVNYRHLSMLCDVMTKHGILMAITRHGINRAETSALARSSFEETVEILMEAAACAELDQCQGVAENIIMGQVAPLGTGNFKVMLDEKSLNAMAMKAGIRARDKYGSATPGAFTPYVNPEKTPFYPSGANGFANGGGDAMFSPIISAGAYMNGGFSPVPIGASAASPAFMGGAGAQSPFVPKSPQYSPTSPGYSPTSPGYSPTSPGYSPTSPGYSPTSPSYSPTSPGYSPTSPGYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPAYSPTSPSYSPTSPAYSPTSPSYSPTSPKYSPTSPSYSPTSPSYSPTSPKYSPTSPQYSPTSPQYSPTSPQYSPTSPQYAATSPAYQGSSATAAKQKSSANGSNETK