ctcae5:C143163 Adverse Event by System Organ Class Adverse Event by System Organ Class Adverse Event by System Organ Class Adverse Event by System Organ Class PT CTCAE Adverse Event by System Organ Class PT NCI ctcae5:C143164 Blood and Lymphatic System Disorders, CTCAE C143164 Blood and Lymphatic System Disorders Blood and Lymphatic System Disorders Blood and Lymphatic System Disorders, CTCAE PT NCI ctcae5:C143165 Cardiac Disorders, CTCAE C143165 Cardiac Disorders Cardiac Disorders Cardiac Disorders, CTCAE PT NCI ctcae5:C143166 Endocrine Disorders, CTCAE C143166 Endocrine Disorders Endocrine Disorders Endocrine Disorders, CTCAE PT NCI ctcae5:C143167 Eye Disorders, CTCAE C143167 Eye Disorders Eye Disorders Eye Disorders, CTCAE PT NCI ctcae5:C143169 General Disorders and Administration Site Conditions, CTCAE C143169 General Disorders and Administration Site Conditions General Disorders and Administration Site Conditions General Disorders and Administration Site Conditions, CTCAE PT NCI ctcae5:C143170 Hepatobiliary Disorders, CTCAE C143170 Hepatobiliary Disorders Hepatobiliary Disorders Hepatobiliary Disorders, CTCAE PT NCI ctcae5:C143171 Infections and Infestations, CTCAE C143171 Infections and Infestations Infections and Infestations Infections and Infestations, CTCAE PT NCI ctcae5:C143172 Injury, Poisoning and Procedural Complications, CTCAE C143172 Injury, Poisoning and Procedural Complications Injury, Poisoning and Procedural Complications Injury, Poisoning and Procedural Complications, CTCAE PT NCI ctcae5:C143173 Investigations, CTCAE C143173 Investigations Investigations Investigations, CTCAE PT NCI ctcae5:C143174 Metabolism and Nutrition Disorders, CTCAE C143174 Metabolism and Nutrition Disorders Metabolism and Nutrition Disorders Metabolism and Nutrition Disorders, CTCAE PT NCI ctcae5:C143175 Musculoskeletal and Connective Tissue Disorders, CTCAE C143175 Musculoskeletal and Connective Tissue Disorders Musculoskeletal and Connective Tissue Disorders Musculoskeletal and Connective Tissue Disorders, CTCAE PT NCI ctcae5:C143176 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE C143176 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps), CTCAE PT NCI ctcae5:C143177 Nervous System Disorders, CTCAE C143177 Nervous System Disorders Nervous System Disorders Nervous System Disorders, CTCAE PT NCI ctcae5:C143178 Pregnancy, Puerperium and Perinatal Conditions, CTCAE C143178 Pregnancy, Puerperium and Perinatal Conditions Pregnancy, Puerperium and Perinatal Conditions Pregnancy, Puerperium and Perinatal Conditions, CTCAE PT NCI ctcae5:C143179 Renal and Urinary Disorders, CTCAE C143179 Renal and Urinary Disorders Renal and Urinary Disorders Renal and Urinary Disorders, CTCAE PT NCI ctcae5:C143180 Reproductive System and Breast Disorders, CTCAE C143180 Reproductive System and Breast Disorders Reproductive System and Breast Disorders Reproductive System and Breast Disorders, CTCAE PT NCI ctcae5:C143181 Respiratory, Thoracic and Mediastinal Disorders, CTCAE C143181 Respiratory, Thoracic and Mediastinal Disorders Respiratory, Thoracic and Mediastinal Disorders Respiratory, Thoracic and Mediastinal Disorders, CTCAE PT NCI ctcae5:C143182 Skin and Subcutaneous Tissue Disorders, CTCAE C143182 Skin and Subcutaneous Tissue Disorders Skin and Subcutaneous Tissue Disorders Skin and Subcutaneous Tissue Disorders, CTCAE PT NCI ctcae5:C143183 Vascular Disorders, CTCAE C143183 Vascular Disorders Vascular Disorders Vascular Disorders, CTCAE PT NCI ctcae5:C143184 Congenital, Familial and Genetic Disorders, CTCAE C143184 Congenital, Familial and Genetic Disorders Congenital, Familial and Genetic Disorders Congenital, Familial and Genetic Disorders, CTCAE PT NCI ctcae5:C143185 Ear and Labyrinth Disorders, CTCAE C143185 Ear and Labyrinth Disorders Ear and Labyrinth Disorders Ear and Labyrinth Disorders, CTCAE PT NCI ctcae5:C143186 Immune System Disorders, CTCAE C143186 Immune System Disorders Immune System Disorders Immune System Disorders, CTCAE PT NCI ctcae5:C143187 Psychiatric Disorders, CTCAE C143187 Psychiatric Disorders Psychiatric Disorders Psychiatric Disorders, CTCAE PT NCI ctcae5:C143188 Social Circumstances, CTCAE C143188 Social Circumstances Social Circumstances Social Circumstances, CTCAE PT NCI ctcae5:C143189 Surgical and Medical Procedures, CTCAE C143189 Surgical and Medical Procedures Surgical and Medical Procedures Surgical and Medical Procedures, CTCAE PT NCI ctcae5:C143190 A disorder characterized by laboratory test results that indicate an increased number of eosinophils in the blood. A disorder characterized by laboratory test results that indicate an increased number of eosinophils in the blood. Eosinophilia Eosinophilia, CTCAE 10014950 C143190 Eosinophilia Eosinophilia A disorder characterized by laboratory test results that indicate an increased number of eosinophils in the blood. NCI A disorder characterized by laboratory test results that indicate an increased number of eosinophils in the blood. CTCAE_v5 Eosinophilia PT CTCAE_v5 Eosinophilia, CTCAE PT NCI ctcae5:C143191 A disorder characterized by laboratory test results that indicate increased methemoglobin in the blood. A disorder characterized by laboratory test results that indicate increased methemoglobin in the blood. Methemoglobinemia Methemoglobinemia, CTCAE 10027506 C143191 Methemoglobinemia Methemoglobinemia A disorder characterized by laboratory test results that indicate increased methemoglobin in the blood. NCI A disorder characterized by laboratory test results that indicate increased methemoglobin in the blood. CTCAE_v5 Methemoglobinemia PT CTCAE_v5 Methemoglobinemia, CTCAE PT NCI ctcae5:C143192 A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. Cyanosis Cyanosis, CTCAE 10011703 C143192 Cyanosis Cyanosis A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. NCI A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. CTCAE_v5 Cyanosis PT CTCAE_v5 Cyanosis, CTCAE PT NCI ctcae5:C143193 A disorder characterized by inflammation and cellular infiltration of the pituitary gland. A disorder characterized by inflammation and cellular infiltration of the pituitary gland. Hypophysitis Hypophysitis, CTCAE 10062767 C143193 Hypophysitis Hypophysitis A disorder characterized by inflammation and cellular infiltration of the pituitary gland. NCI A disorder characterized by inflammation and cellular infiltration of the pituitary gland. CTCAE_v5 Hypophysitis PT CTCAE_v5 Hypophysitis, CTCAE PT NCI ctcae5:C143194 A disorder characterized by a decrease in production of hormones from the pituitary gland. A disorder characterized by a decrease in production of hormones from the pituitary gland. Hypopituitarism Hypopituitarism, CTCAE 10021067 C143194 Hypopituitarism Hypopituitarism A disorder characterized by a decrease in production of hormones from the pituitary gland. NCI A disorder characterized by a decrease in production of hormones from the pituitary gland. CTCAE_v5 Hypopituitarism PT CTCAE_v5 Hypopituitarism, CTCAE PT NCI ctcae5:C143195 A disorder characterized by low testosterone. A disorder characterized by low testosterone. Testosterone Deficiency, CTCAE Testosterone deficiency 10067734 C143195 Testosterone deficiency Testosterone deficiency A disorder characterized by low testosterone. NCI A disorder characterized by low testosterone. CTCAE_v5 Testosterone Deficiency, CTCAE PT NCI Testosterone deficiency PT CTCAE_v5 ctcae5:C143196 A disorder characterized by a decrease in visual acuity. A disorder characterized by a decrease in visual acuity. Vision Decreased, CTCAE Vision decreased 10047516 C143196 Vision decreased Vision decreased A disorder characterized by a decrease in visual acuity. NCI A disorder characterized by a decrease in visual acuity. CTCAE_v5 Vision Decreased, CTCAE PT NCI Vision decreased PT CTCAE_v5 ctcae5:C143197 A disorder characterized by a tear in the lining of the anus. A disorder characterized by a tear in the lining of the anus. Anal Fissure, CTCAE Anal fissure 10002153 C143197 Anal fissure Anal fissure A disorder characterized by a tear in the lining of the anus. NCI A disorder characterized by a tear in the lining of the anus. CTCAE_v5 Anal Fissure, CTCAE PT NCI Anal fissure PT CTCAE_v5 ctcae5:C143198 To expel gas noisily from the mouth. To expel gas noisily from the mouth. Belching Belching, CTCAE 10004222 C143198 Belching Belching To expel gas noisily from the mouth. NCI To expel gas noisily from the mouth. CTCAE_v5 Belching PT CTCAE_v5 Belching, CTCAE PT NCI ctcae5:C143199 A disorder characterized by accumulation of milky fluid in the peritoneal cavity. A disorder characterized by accumulation of milky fluid in the peritoneal cavity. Chylous Ascites, CTCAE Chylous ascites 10009167 C143199 Chylous ascites Chylous ascites A disorder characterized by accumulation of milky fluid in the peritoneal cavity. NCI A disorder characterized by accumulation of milky fluid in the peritoneal cavity. CTCAE_v5 Chylous Ascites, CTCAE PT NCI Chylous ascites PT CTCAE_v5 ctcae5:C143200 A disorder characterized by a tear in the lining of the rectum. A disorder characterized by a tear in the lining of the rectum. Rectal Fissure, CTCAE Rectal fissure 10064993 C143200 Rectal fissure Rectal fissure A disorder characterized by a tear in the lining of the rectum. NCI A disorder characterized by a tear in the lining of the rectum. CTCAE_v5 Rectal Fissure, CTCAE PT NCI Rectal fissure PT CTCAE_v5 ctcae5:C143201 Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5. Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5. Disease Progression, CTCAE Disease progression 10061818 C143201 Disease progression Disease progression Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5. NCI Death due to disease progression that cannot be attributed to a CTCAE term associated with Grade 5. CTCAE_v5 Disease Progression, CTCAE PT NCI Disease progression PT CTCAE_v5 ctcae5:C143202 A disorder characterized by fluid accumulation in the tissues of the body including the skin. A disorder characterized by fluid accumulation in the tissues of the body including the skin. Generalized Edema, CTCAE Generalized edema 10018112 C143202 Generalized edema Generalized edema A disorder characterized by fluid accumulation in the tissues of the body including the skin. NCI A disorder characterized by fluid accumulation in the tissues of the body including the skin. CTCAE_v5 Generalized Edema, CTCAE PT NCI Generalized edema PT CTCAE_v5 ctcae5:C143203 A disorder characterized by lymph node enlargement after vaccination A disorder characterized by lymph node enlargement after vaccination Vaccination Site Lymphadenopathy, CTCAE Vaccination site lymphadenopathy 10069480 C143203 Vaccination site lymphadenopathy Vaccination site lymphadenopathy A disorder characterized by lymph node enlargement after vaccination NCI A disorder characterized by lymph node enlargement after vaccination CTCAE_v5 Vaccination Site Lymphadenopathy, CTCAE PT NCI Vaccination site lymphadenopathy PT CTCAE_v5 ctcae5:C143204 A disorder characterized by occlusion of the hepatic veins and typically presents with abdominal pain, ascites and hepatomegaly. A disorder characterized by occlusion of the hepatic veins and typically presents with abdominal pain, ascites and hepatomegaly. Budd-Chiari Syndrome, CTCAE Budd-Chiari syndrome 10006537 C143204 Budd-Chiari syndrome Budd-Chiari syndrome A disorder characterized by occlusion of the hepatic veins and typically presents with abdominal pain, ascites and hepatomegaly. NCI A disorder characterized by occlusion of the hepatic veins and typically presents with abdominal pain, ascites and hepatomegaly. CTCAE_v5 Budd-Chiari Syndrome, CTCAE PT NCI Budd-Chiari syndrome PT CTCAE_v5 ctcae5:C143205 A disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked. A disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked. Sinusoidal Obstruction Syndrome, CTCAE Sinusoidal obstruction syndrome 10063675 C143205 Sinusoidal obstruction syndrome Sinusoidal obstruction syndrome A disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked. NCI A disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked. CTCAE_v5 Sinusoidal Obstruction Syndrome, CTCAE PT NCI Sinusoidal obstruction syndrome PT CTCAE_v5 ctcae5:C143206 A disorder characterized by the presence of bacteria in the blood stream. A disorder characterized by the presence of bacteria in the blood stream. Bacteremia Bacteremia, CTCAE 10003999 C143206 Bacteremia Bacteremia A disorder characterized by the presence of bacteria in the blood stream. NCI A disorder characterized by the presence of bacteria in the blood stream. CTCAE_v5 Bacteremia PT CTCAE_v5 Bacteremia, CTCAE PT NCI ctcae5:C143207 A disorder characterized by the reactivation of cytomegalovirus (CMV). A disorder characterized by the reactivation of cytomegalovirus (CMV). Cytomegalovirus Infection Reactivation, CTCAE Cytomegalovirus infection reactivation 10058666 C143207 Cytomegalovirus infection reactivation Cytomegalovirus infection reactivation A disorder characterized by the reactivation of cytomegalovirus (CMV). NCI A disorder characterized by the reactivation of cytomegalovirus (CMV). CTCAE_v5 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C143208 A disorder characterized by the reactivation of Epstein-Barr virus (EBV). A disorder characterized by the reactivation of Epstein-Barr virus (EBV). Epstein-Barr Virus Infection Reactivation, CTCAE Epstein-Barr virus infection reactivation 10015109 C143208 Epstein-Barr virus infection reactivation Epstein-Barr virus infection reactivation A disorder characterized by the reactivation of Epstein-Barr virus (EBV). NCI A disorder characterized by the reactivation of Epstein-Barr virus (EBV). CTCAE_v5 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C143209 A disorder characterized by inflammation or infection of the hair follicles. A disorder characterized by inflammation or infection of the hair follicles. Folliculitis Folliculitis, CTCAE 10016936 C143209 Folliculitis Folliculitis A disorder characterized by inflammation or infection of the hair follicles. NCI A disorder characterized by inflammation or infection of the hair follicles. CTCAE_v5 Folliculitis PT CTCAE_v5 Folliculitis, CTCAE PT NCI ctcae5:C143210 A disorder characterized by the presence of fungus in the blood stream. A disorder characterized by the presence of fungus in the blood stream. Fungemia Fungemia, CTCAE 10017544 C143210 Fungemia Fungemia A disorder characterized by the presence of fungus in the blood stream. NCI A disorder characterized by the presence of fungus in the blood stream. CTCAE_v5 Fungemia PT CTCAE_v5 Fungemia, CTCAE PT NCI ctcae5:C143211 A disorder characterized by the reactivation of hepatitis B virus. A disorder characterized by the reactivation of hepatitis B virus. Hepatitis B Reactivation, CTCAE Hepatitis B reactivation 10058827 C143211 Hepatitis B reactivation Hepatitis B reactivation A disorder characterized by the reactivation of hepatitis B virus. NCI A disorder characterized by the reactivation of hepatitis B virus. CTCAE_v5 Hepatitis B Reactivation, CTCAE PT NCI Hepatitis B reactivation PT CTCAE_v5 ctcae5:C143212 A disorder characterized by the reactivation of Herpes simplex virus A disorder characterized by the reactivation of Herpes simplex virus Herpes Simplex Reactivation, CTCAE Herpes simplex reactivation 10080137 C143212 Herpes simplex reactivation Herpes simplex reactivation A disorder characterized by the reactivation of Herpes simplex virus NCI A disorder characterized by the reactivation of Herpes simplex virus CTCAE_v5 Herpes Simplex Reactivation, CTCAE PT NCI Herpes simplex reactivation PT CTCAE_v5 ctcae5:C143213 A disorder characterized by the reactivation of herpes zoster virus. A disorder characterized by the reactivation of herpes zoster virus. Shingles Shingles, CTCAE 10040555 C143213 Shingles Shingles A disorder characterized by the reactivation of herpes zoster virus. NCI A disorder characterized by the reactivation of herpes zoster virus. CTCAE_v5 Shingles PT CTCAE_v5 Shingles, CTCAE PT NCI ctcae5:C143214 A disorder characterized by a suspected candidal infection involving an oral mucosal surface. A disorder characterized by a suspected candidal infection involving an oral mucosal surface. Thrush Thrush, CTCAE 10043649 C143214 Thrush Thrush A disorder characterized by a suspected candidal infection involving an oral mucosal surface. NCI A disorder characterized by a suspected candidal infection involving an oral mucosal surface. CTCAE_v5 Thrush PT CTCAE_v5 Thrush, CTCAE PT NCI ctcae5:C143215 A disorder characterized by the presence of a virus in the blood stream. A disorder characterized by the presence of a virus in the blood stream. Viremia Viremia, CTCAE 10054688 C143215 Viremia Viremia A disorder characterized by the presence of a virus in the blood stream. NCI A disorder characterized by the presence of a virus in the blood stream. CTCAE_v5 Viremia PT CTCAE_v5 Viremia, CTCAE PT NCI ctcae5:C143216 A disorder that occurs after the injection of a substance with antigenic properties, administered to activate the immune system. A disorder that occurs after the injection of a substance with antigenic properties, administered to activate the immune system. Vaccination Complication, CTCAE Vaccination complication 10046861 C143216 Vaccination complication Vaccination complication A disorder that occurs after the injection of a substance with antigenic properties, administered to activate the immune system. NCI A disorder that occurs after the injection of a substance with antigenic properties, administered to activate the immune system. CTCAE_v5 Vaccination Complication, CTCAE PT NCI Vaccination complication PT CTCAE_v5 ctcae5:C143217 A finding based on laboratory test results that indicate a decrease in levels of bicarbonate in a venous blood specimen. A finding based on laboratory test results that indicate a decrease in levels of bicarbonate in a venous blood specimen. Blood Bicarbonate Decreased, CTCAE Blood bicarbonate decreased 10005359 C143217 Blood bicarbonate decreased Blood bicarbonate decreased A finding based on laboratory test results that indicate a decrease in levels of bicarbonate in a venous blood specimen. NCI A finding based on laboratory test results that indicate a decrease in levels of bicarbonate in a venous blood specimen. CTCAE_v5 Blood Bicarbonate Decreased, CTCAE PT NCI Blood bicarbonate decreased PT CTCAE_v5 ctcae5:C143218 A finding based on laboratory test results that indicate increased levels of lactate dehydrogenase in the blood specimen. A finding based on laboratory test results that indicate increased levels of lactate dehydrogenase in the blood specimen. Blood Lactate Dehydrogenase Increased, CTCAE Blood lactate dehydrogenase increased 10005630 C143218 Blood lactate dehydrogenase increased Blood lactate dehydrogenase increased A finding based on laboratory test results that indicate increased levels of lactate dehydrogenase in the blood specimen. NCI A finding based on laboratory test results that indicate increased levels of lactate dehydrogenase in the blood specimen. CTCAE_v5 Blood Lactate Dehydrogenase Increased, CTCAE PT NCI Blood lactate dehydrogenase increased PT CTCAE_v5 ctcae5:C143219 A disorder characterized by Electrocardiogram T wave amplitude changes. A disorder characterized by Electrocardiogram T wave amplitude changes. Electrocardiogram T Wave Abnormal, CTCAE Electrocardiogram T wave abnormal 10050380 C143219 Electrocardiogram T wave abnormal Electrocardiogram T wave abnormal A disorder characterized by Electrocardiogram T wave amplitude changes. NCI A disorder characterized by Electrocardiogram T wave amplitude changes. CTCAE_v5 Electrocardiogram T Wave Abnormal, CTCAE PT NCI Electrocardiogram T wave abnormal PT CTCAE_v5 ctcae5:C143220 A disorder characterized by an increase in thyroid stimulating hormone. A disorder characterized by an increase in thyroid stimulating hormone. Thyroid Stimulating Hormone Increased, CTCAE Thyroid stimulating hormone increased 10043770 C143220 Thyroid stimulating hormone increased Thyroid stimulating hormone increased A disorder characterized by an increase in thyroid stimulating hormone. NCI A disorder characterized by an increase in thyroid stimulating hormone. CTCAE_v5 Thyroid Stimulating Hormone Increased, CTCAE PT NCI Thyroid stimulating hormone increased PT CTCAE_v5 ctcae5:C143221 A disorder characterized by laboratory test results that indicate an elevation in the concentration of lipids in blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of lipids in blood. Hyperlipidemia Hyperlipidemia, CTCAE 10020667 C143221 Hyperlipidemia Hyperlipidemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of lipids in blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of lipids in blood. CTCAE_v5 Hyperlipidemia PT CTCAE_v5 Hyperlipidemia, CTCAE PT NCI ctcae5:C143222 A disorder characterized by laboratory test results that indicate an elevation in the concentration of phosphate in a blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of phosphate in a blood. Hyperphosphatemia Hyperphosphatemia, CTCAE 10020712 C143222 Hyperphosphatemia Hyperphosphatemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of phosphate in a blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of phosphate in a blood. CTCAE_v5 Hyperphosphatemia PT CTCAE_v5 Hyperphosphatemia, CTCAE PT NCI ctcae5:C143223 A disorder characterized by a necrotic process occurring in the soft tissues of the chest wall including breast. A disorder characterized by a necrotic process occurring in the soft tissues of the chest wall including breast. Chest Wall Necrosis, CTCAE Chest wall necrosis 10048831 C143223 Chest wall necrosis Chest wall necrosis A disorder characterized by a necrotic process occurring in the soft tissues of the chest wall including breast. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the chest wall including breast. CTCAE_v5 Chest Wall Necrosis, CTCAE PT NCI Chest wall necrosis PT CTCAE_v5 ctcae5:C143224 A disorder characterized by marked cramping sensation originating from a muscle or group of muscles. A disorder characterized by marked cramping sensation originating from a muscle or group of muscles. Muscle Cramp, CTCAE Muscle cramp 10028294 C143224 Muscle cramp Muscle cramp A disorder characterized by marked cramping sensation originating from a muscle or group of muscles. NCI A disorder characterized by marked cramping sensation originating from a muscle or group of muscles. CTCAE_v5 Muscle Cramp, CTCAE PT NCI Muscle cramp PT CTCAE_v5 ctcae5:C143225 A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. Osteonecrosis Osteonecrosis, CTCAE 10031264 C143225 Osteonecrosis Osteonecrosis A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. NCI A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. CTCAE_v5 Osteonecrosis PT CTCAE_v5 Osteonecrosis, CTCAE PT NCI ctcae5:C143226 A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. Rhabdomyolysis Rhabdomyolysis, CTCAE 10039020 C143226 Rhabdomyolysis Rhabdomyolysis A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. NCI A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. CTCAE_v5 Rhabdomyolysis PT CTCAE_v5 Rhabdomyolysis, CTCAE PT NCI ctcae5:C143227 A disorder characterized by an injury of the rotator cuff. A disorder characterized by an injury of the rotator cuff. Rotator Cuff Injury, CTCAE Rotator cuff injury 10039226 C143227 Rotator cuff injury Rotator cuff injury A disorder characterized by an injury of the rotator cuff. NCI A disorder characterized by an injury of the rotator cuff. CTCAE_v5 Rotator Cuff Injury, CTCAE PT NCI Rotator cuff injury PT CTCAE_v5 ctcae5:C143228 A disorder characterized by the presence of one or more warts. A disorder characterized by the presence of one or more warts. Skin Papilloma, CTCAE Skin papilloma 10040907 C143228 Skin papilloma Skin papilloma A disorder characterized by the presence of one or more warts. NCI A disorder characterized by the presence of one or more warts. CTCAE_v5 Skin Papilloma, CTCAE PT NCI Skin papilloma PT CTCAE_v5 ctcae5:C143229 A disorder characterized by bleeding in a tumor. A disorder characterized by bleeding in a tumor. Tumor Hemorrhage, CTCAE Tumor hemorrhage 10055351 C143229 Tumor hemorrhage Tumor hemorrhage A disorder characterized by bleeding in a tumor. NCI A disorder characterized by bleeding in a tumor. CTCAE_v5 Tumor Hemorrhage, CTCAE PT NCI Tumor hemorrhage PT CTCAE_v5 ctcae5:C143230 A disorder characterized by a change in the sense of smell. A disorder characterized by a change in the sense of smell. Anosmia Anosmia, CTCAE 10002653 C143230 Anosmia Anosmia A disorder characterized by a change in the sense of smell. NCI A disorder characterized by a change in the sense of smell. CTCAE_v5 Anosmia PT CTCAE_v5 Anosmia, CTCAE PT NCI ctcae5:C143231 A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis. A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis. Guillain-Barre Syndrome, CTCAE Guillain-Barre syndrome 10018767 C143231 Guillain-Barre syndrome Guillain-Barre syndrome A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis. NCI A disorder characterized by the body's immune system attacking the peripheral nervous system causing ascending paralysis. CTCAE_v5 Guillain-Barre Syndrome, CTCAE PT NCI Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C143232 A disorder characterized by weakness and rapid fatigue of any of the skeletal muscles. A disorder characterized by weakness and rapid fatigue of any of the skeletal muscles. Myasthenia Gravis, CTCAE Myasthenia gravis 10028417 C143232 Myasthenia gravis Myasthenia gravis A disorder characterized by weakness and rapid fatigue of any of the skeletal muscles. NCI A disorder characterized by weakness and rapid fatigue of any of the skeletal muscles. CTCAE_v5 Myasthenia Gravis, CTCAE PT NCI Myasthenia gravis PT CTCAE_v5 ctcae5:C143233 A disorder characterized by pressure on the spinal cord. A disorder characterized by pressure on the spinal cord. Spinal Cord Compression, CTCAE Spinal cord compression 10041549 C143233 Spinal cord compression Spinal cord compression A disorder characterized by pressure on the spinal cord. NCI A disorder characterized by pressure on the spinal cord. CTCAE_v5 Spinal Cord Compression, CTCAE PT NCI Spinal cord compression PT CTCAE_v5 ctcae5:C143234 A disorder characterized by less than normal deep tendon reflexes. A disorder characterized by less than normal deep tendon reflexes. Tendon Reflex Decreased, CTCAE Tendon reflex decreased 10043245 C143234 Tendon reflex decreased Tendon reflex decreased A disorder characterized by less than normal deep tendon reflexes. NCI A disorder characterized by less than normal deep tendon reflexes. CTCAE_v5 Tendon Reflex Decreased, CTCAE PT NCI Tendon reflex decreased PT CTCAE_v5 ctcae5:C143235 A disorder characterized by dysfunction of the trochlear nerve (fourth cranial nerve). A disorder characterized by dysfunction of the trochlear nerve (fourth cranial nerve). Trochlear Nerve Disorder, CTCAE Trochlear nerve disorder 10074765 C143235 Trochlear nerve disorder Trochlear nerve disorder A disorder characterized by dysfunction of the trochlear nerve (fourth cranial nerve). NCI A disorder characterized by dysfunction of the trochlear nerve (fourth cranial nerve). CTCAE_v5 Trochlear Nerve Disorder, CTCAE PT NCI Trochlear nerve disorder PT CTCAE_v5 ctcae5:C143236 Death in utero. Death in utero. Pregnancy Loss, CTCAE Pregnancy loss 10072314 C143236 Pregnancy loss Pregnancy loss Death in utero. NCI Death in utero. CTCAE_v5 Pregnancy Loss, CTCAE PT NCI Pregnancy loss PT CTCAE_v5 ctcae5:C143237 A disorder characterized by painful urination. A disorder characterized by painful urination. Dysuria Dysuria, CTCAE 10013990 C143237 Dysuria Dysuria A disorder characterized by painful urination. NCI A disorder characterized by painful urination. CTCAE_v5 Dysuria PT CTCAE_v5 Dysuria, CTCAE PT NCI ctcae5:C143238 A disorder characterized by laboratory test results that indicate glucose in the urine. A disorder characterized by laboratory test results that indicate glucose in the urine. Glucosuria Glucosuria, CTCAE 10068405 C143238 Glucosuria Glucosuria A disorder characterized by laboratory test results that indicate glucose in the urine. NCI A disorder characterized by laboratory test results that indicate glucose in the urine. CTCAE_v5 Glucosuria PT CTCAE_v5 Glucosuria, CTCAE PT NCI ctcae5:C143239 A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. Nephrotic Syndrome, CTCAE Nephrotic syndrome 10029164 C143239 Nephrotic syndrome Nephrotic syndrome A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. NCI A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. CTCAE_v5 Nephrotic Syndrome, CTCAE PT NCI Nephrotic syndrome PT CTCAE_v5 ctcae5:C143240 A disorder characterized by the abnormal absence of menses for at least three consecutive menstrual cycles A disorder characterized by the abnormal absence of menses for at least three consecutive menstrual cycles Amenorrhea Amenorrhea, CTCAE 10001927 C143240 Amenorrhea Amenorrhea A disorder characterized by the abnormal absence of menses for at least three consecutive menstrual cycles NCI A disorder characterized by the abnormal absence of menses for at least three consecutive menstrual cycles CTCAE_v5 Amenorrhea PT CTCAE_v5 Amenorrhea, CTCAE PT NCI ctcae5:C143241 A disorder characterized by a sensation of marked discomfort in the oropharynx. A disorder characterized by a sensation of marked discomfort in the oropharynx. Oropharyngeal Pain, CTCAE Oropharyngeal pain 10068319 C143241 Oropharyngeal pain Oropharyngeal pain A disorder characterized by a sensation of marked discomfort in the oropharynx. NCI A disorder characterized by a sensation of marked discomfort in the oropharynx. CTCAE_v5 Oropharyngeal Pain, CTCAE PT NCI Oropharyngeal pain PT CTCAE_v5 ctcae5:C143242 A disorder characterized by excessive mucous secretions draining from the nose. A disorder characterized by excessive mucous secretions draining from the nose. Rhinorrhea Rhinorrhea, CTCAE 10039100 C143242 Rhinorrhea Rhinorrhea A disorder characterized by excessive mucous secretions draining from the nose. NCI A disorder characterized by excessive mucous secretions draining from the nose. CTCAE_v5 Rhinorrhea PT CTCAE_v5 Rhinorrhea, CTCAE PT NCI ctcae5:C143243 A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters. A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters. Eczema Eczema, CTCAE 10014184 C143243 Eczema Eczema A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters. NCI A disorder characterized by skin which becomes itchy, red, inflamed, crusty, thick, scaly, and/or forms blisters. CTCAE_v5 Eczema PT CTCAE_v5 Eczema, CTCAE PT NCI ctcae5:C143244 A disorder characterized by change in hair color or loss of normal pigmentation. A disorder characterized by change in hair color or loss of normal pigmentation. Hair Color Changes, CTCAE Hair color changes 10055525 C143244 Hair color changes Hair color changes A disorder characterized by change in hair color or loss of normal pigmentation. NCI A disorder characterized by change in hair color or loss of normal pigmentation. CTCAE_v5 Hair Color Changes, CTCAE PT NCI Hair color changes PT CTCAE_v5 ctcae5:C143245 A disorder characterized by a change in the way the hair feels. A disorder characterized by a change in the way the hair feels. Hair Texture Abnormal, CTCAE Hair texture abnormal 10019049 C143245 Hair texture abnormal Hair texture abnormal A disorder characterized by a change in the way the hair feels. NCI A disorder characterized by a change in the way the hair feels. CTCAE_v5 Hair Texture Abnormal, CTCAE PT NCI Hair texture abnormal PT CTCAE_v5 ctcae5:C143246 A disorder characterized by a thickening of the outer layer of the skin. A disorder characterized by a thickening of the outer layer of the skin. Hyperkeratosis Hyperkeratosis, CTCAE 10020649 C143246 Hyperkeratosis Hyperkeratosis A disorder characterized by a thickening of the outer layer of the skin. NCI A disorder characterized by a thickening of the outer layer of the skin. CTCAE_v5 Hyperkeratosis PT CTCAE_v5 Hyperkeratosis, CTCAE PT NCI ctcae5:C143247 A disorder characterized by a change in the nails. A disorder characterized by a change in the nails. Nail Changes, CTCAE 5.0 Nail changes 10028689 C143247 Nail changes Nail changes A disorder characterized by a change in the nails. NCI A disorder characterized by a change in the nails. CTCAE_v5 Nail Changes, CTCAE 5.0 PT NCI Nail changes PT CTCAE_v5 ctcae5:C143248 A disorder characterized by air in the subcutaneous tissue. A disorder characterized by air in the subcutaneous tissue. Subcutaneous Emphysema, CTCAE Subcutaneous emphysema 10042344 C143248 Subcutaneous emphysema Subcutaneous emphysema A disorder characterized by air in the subcutaneous tissue. NCI A disorder characterized by air in the subcutaneous tissue. CTCAE_v5 Subcutaneous Emphysema, CTCAE PT NCI Subcutaneous emphysema PT CTCAE_v5 ctcae5:C143249 A disorder characterized by occlusion of an arterial vessel by a blood clot that develops in an artery. A disorder characterized by occlusion of an arterial vessel by a blood clot that develops in an artery. Arterial Thromboembolism, CTCAE Arterial thromboembolism 10073529 C143249 Arterial thromboembolism Arterial thromboembolism A disorder characterized by occlusion of an arterial vessel by a blood clot that develops in an artery. NCI A disorder characterized by occlusion of an arterial vessel by a blood clot that develops in an artery. CTCAE_v5 Arterial Thromboembolism, CTCAE PT NCI Arterial thromboembolism PT CTCAE_v5 ctcae5:C143253 A disorder characterized by swelling of the abdomen. A disorder characterized by swelling of the abdomen. Abdominal Distension, CTCAE Abdominal distension 10000060 C143253 Abdominal distension Abdominal distension A disorder characterized by swelling of the abdomen. NCI A disorder characterized by swelling of the abdomen. CTCAE_v5 Abdominal Distension, CTCAE PT NCI Abdominal distension PT CTCAE_v5 ctcae5:C143254 A disorder characterized by an infectious process involving the abdominal cavity. A disorder characterized by an infectious process involving the abdominal cavity. Abdominal Infection, CTCAE Abdominal infection 10056519 C143254 Abdominal infection Abdominal infection A disorder characterized by an infectious process involving the abdominal cavity. NCI A disorder characterized by an infectious process involving the abdominal cavity. CTCAE_v5 Abdominal Infection, CTCAE PT NCI Abdominal infection PT CTCAE_v5 ctcae5:C143255 A disorder characterized by a sensation of marked discomfort in the abdominal region. A disorder characterized by a sensation of marked discomfort in the abdominal region. Abdominal Pain, CTCAE Abdominal pain 10000081 C143255 Abdominal pain Abdominal pain A disorder characterized by a sensation of marked discomfort in the abdominal region. NCI A disorder characterized by a sensation of marked discomfort in the abdominal region. CTCAE_v5 Abdominal Pain, CTCAE PT NCI Abdominal pain PT CTCAE_v5 ctcae5:C143256 A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. Abdominal Soft Tissue Necrosis, CTCAE Abdominal soft tissue necrosis 10065775 C143256 Abdominal soft tissue necrosis Abdominal soft tissue necrosis A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the abdominal wall. CTCAE_v5 Abdominal Soft Tissue Necrosis, CTCAE PT NCI Abdominal soft tissue necrosis PT CTCAE_v5 ctcae5:C143257 A disorder characterized by dysfunction of the abducens nerve (sixth cranial nerve). A disorder characterized by dysfunction of the abducens nerve (sixth cranial nerve). Abducens Nerve Disorder, CTCAE Abducens nerve disorder 10053662 C143257 Abducens nerve disorder Abducens nerve disorder A disorder characterized by dysfunction of the abducens nerve (sixth cranial nerve). NCI A disorder characterized by dysfunction of the abducens nerve (sixth cranial nerve). CTCAE_v5 Abducens Nerve Disorder, CTCAE PT NCI Abducens nerve disorder PT CTCAE_v5 ctcae5:C143258 A disorder characterized by dysfunction of the accessory nerve (eleventh cranial nerve). A disorder characterized by dysfunction of the accessory nerve (eleventh cranial nerve). Accessory Nerve Disorder, CTCAE Accessory nerve disorder 10060929 C143258 Accessory nerve disorder Accessory nerve disorder A disorder characterized by dysfunction of the accessory nerve (eleventh cranial nerve). NCI A disorder characterized by dysfunction of the accessory nerve (eleventh cranial nerve). CTCAE_v5 Accessory Nerve Disorder, CTCAE PT NCI Accessory nerve disorder PT CTCAE_v5 ctcae5:C143259 A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. Acidosis Acidosis, CTCAE 10000486 C143259 Acidosis Acidosis A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. NCI A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues. CTCAE_v5 Acidosis PT CTCAE_v5 Acidosis, CTCAE PT NCI ctcae5:C143260 A disorder characterized by dysfunction of the acoustic nerve (eighth cranial nerve). A disorder characterized by dysfunction of the acoustic nerve (eighth cranial nerve). Acoustic Nerve Disorder NOS, CTCAE Acoustic nerve disorder NOS 10000521 C143260 Acoustic nerve disorder NOS Acoustic nerve disorder NOS A disorder characterized by dysfunction of the acoustic nerve (eighth cranial nerve). NCI A disorder characterized by dysfunction of the acoustic nerve (eighth cranial nerve). CTCAE_v5 Acoustic Nerve Disorder NOS, CTCAE PT NCI Acoustic nerve disorder NOS PT CTCAE_v5 ctcae5:C143261 A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. Activated Partial Thromboplastin Time Prolonged, CTCAE Activated partial thromboplastin time prolonged 10000636 C143261 Activated partial thromboplastin time prolonged Activated partial thromboplastin time prolonged A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. NCI A finding based on laboratory test results in which the partial thromboplastin time is found to be greater than the control value. As a possible indicator of coagulopathy, a prolonged partial thromboplastin time (PTT) may occur in a variety of diseases and disorders, both primary and related to treatment. CTCAE_v5 Activated Partial Thromboplastin Time Prolonged, CTCAE PT NCI Activated partial thromboplastin time prolonged PT CTCAE_v5 ctcae5:C143262 A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). Acute Kidney Injury, CTCAE Acute kidney injury 10069339 C143262 Acute kidney injury Acute kidney injury A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). NCI A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). CTCAE_v5 Acute Kidney Injury, CTCAE PT NCI Acute kidney injury PT CTCAE_v5 ctcae5:C143266 A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. Akathisia Akathisia, CTCAE 10001540 C143266 Akathisia Akathisia A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. NCI A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. CTCAE_v5 Akathisia PT CTCAE_v5 Akathisia, CTCAE PT NCI ctcae5:C143267 A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. Alanine Aminotransferase Increased, CTCAE Alanine aminotransferase increased 10001551 C143267 Alanine aminotransferase increased Alanine aminotransferase increased A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. NCI A finding based on laboratory test results that indicate an increase in the level of alanine aminotransferase (ALT or SGPT) in the blood specimen. CTCAE_v5 Alanine Aminotransferase Increased, CTCAE PT NCI Alanine aminotransferase increased PT CTCAE_v5 ctcae5:C143268 A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. Alcohol Intolerance, CTCAE Alcohol intolerance 10001598 C143268 Alcohol intolerance Alcohol intolerance A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. NCI A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches. CTCAE_v5 Alcohol Intolerance, CTCAE PT NCI Alcohol intolerance PT CTCAE_v5 ctcae5:C143269 A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. Alkaline Phosphatase Increased, CTCAE Alkaline phosphatase increased 10001675 C143269 Alkaline phosphatase increased Alkaline phosphatase increased A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. NCI A finding based on laboratory test results that indicate an increase in the level of alkaline phosphatase in a blood specimen. CTCAE_v5 Alkaline Phosphatase Increased, CTCAE PT NCI Alkaline phosphatase increased PT CTCAE_v5 ctcae5:C143270 A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. Alkalosis Alkalosis, CTCAE 10001680 C143270 Alkalosis Alkalosis A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. NCI A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. CTCAE_v5 Alkalosis PT CTCAE_v5 Alkalosis, CTCAE PT NCI ctcae5:C143271 A disorder characterized by an adverse local or general response from exposure to an allergen. A disorder characterized by an adverse local or general response from exposure to an allergen. Allergic Reaction, CTCAE Allergic reaction 10001718 C143271 Allergic reaction Allergic reaction A disorder characterized by an adverse local or general response from exposure to an allergen. NCI A disorder characterized by an adverse local or general response from exposure to an allergen. CTCAE_v5 Allergic Reaction, CTCAE PT NCI Allergic reaction PT CTCAE_v5 ctcae5:C143272 A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. Allergic Rhinitis, CTCAE Allergic rhinitis 10001723 C143272 Allergic rhinitis Allergic rhinitis A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. NCI A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching. CTCAE_v5 Allergic Rhinitis, CTCAE PT NCI Allergic rhinitis PT CTCAE_v5 ctcae5:C143274 A disorder characterized by systematic and extensive loss of memory. A disorder characterized by systematic and extensive loss of memory. Amnesia Amnesia, CTCAE 10001949 C143274 Amnesia Amnesia A disorder characterized by systematic and extensive loss of memory. NCI A disorder characterized by systematic and extensive loss of memory. CTCAE_v5 Amnesia PT CTCAE_v5 Amnesia, CTCAE PT NCI ctcae5:C143275 A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. Anal Fistula, CTCAE Anal fistula 10002156 C143275 Anal fistula Anal fistula A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. NCI A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. CTCAE_v5 Anal Fistula, CTCAE PT NCI Anal fistula PT CTCAE_v5 ctcae5:C143276 A disorder characterized by bleeding from the anal region. A disorder characterized by bleeding from the anal region. Anal Hemorrhage, CTCAE Anal hemorrhage 10055226 C143276 Anal hemorrhage Anal hemorrhage A disorder characterized by bleeding from the anal region. NCI A disorder characterized by bleeding from the anal region. CTCAE_v5 Anal Hemorrhage, CTCAE PT NCI Anal hemorrhage PT CTCAE_v5 ctcae5:C143277 A disorder characterized by ulceration or inflammation of the mucous membrane of the anus. A disorder characterized by ulceration or inflammation of the mucous membrane of the anus. Anal Mucositis, CTCAE Anal mucositis 10065721 C143277 Anal mucositis Anal mucositis A disorder characterized by ulceration or inflammation of the mucous membrane of the anus. NCI A disorder characterized by ulceration or inflammation of the mucous membrane of the anus. CTCAE_v5 Anal Mucositis, CTCAE PT NCI Anal mucositis PT CTCAE_v5 ctcae5:C143278 A disorder characterized by a necrotic process occurring in the anal region. A disorder characterized by a necrotic process occurring in the anal region. Anal Necrosis, CTCAE Anal necrosis 10065722 C143278 Anal necrosis Anal necrosis A disorder characterized by a necrotic process occurring in the anal region. NCI A disorder characterized by a necrotic process occurring in the anal region. CTCAE_v5 Anal Necrosis, CTCAE PT NCI Anal necrosis PT CTCAE_v5 ctcae5:C143279 A disorder characterized by a sensation of marked discomfort in the anal region. A disorder characterized by a sensation of marked discomfort in the anal region. Anal Pain, CTCAE Anal pain 10002167 C143279 Anal pain Anal pain A disorder characterized by a sensation of marked discomfort in the anal region. NCI A disorder characterized by a sensation of marked discomfort in the anal region. CTCAE_v5 Anal Pain, CTCAE PT NCI Anal pain PT CTCAE_v5 ctcae5:C143280 A disorder characterized by a narrowing of the lumen of the anal canal. A disorder characterized by a narrowing of the lumen of the anal canal. Anal Stenosis, CTCAE Anal stenosis 10002176 C143280 Anal stenosis Anal stenosis A disorder characterized by a narrowing of the lumen of the anal canal. NCI A disorder characterized by a narrowing of the lumen of the anal canal. CTCAE_v5 Anal Stenosis, CTCAE PT NCI Anal stenosis PT CTCAE_v5 ctcae5:C143281 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the anal canal. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the anal canal. Anal Ulcer, CTCAE Anal ulcer 10002180 C143281 Anal ulcer Anal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the anal canal. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the anal canal. CTCAE_v5 Anal Ulcer, CTCAE PT NCI Anal ulcer PT CTCAE_v5 ctcae5:C143282 A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. Anaphylaxis Anaphylaxis, CTCAE 10002218 C143282 Anaphylaxis Anaphylaxis A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. NCI A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death. CTCAE_v5 Anaphylaxis PT CTCAE_v5 Anaphylaxis, CTCAE PT NCI ctcae5:C143283 A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. Anemia Anemia, CTCAE 10002272 C143283 Anemia Anemia A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. NCI A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. CTCAE_v5 Anemia PT CTCAE_v5 Anemia, CTCAE PT NCI ctcae5:C143284 A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. Ankle Fracture, CTCAE Ankle fracture 10002544 C143284 Ankle fracture Ankle fracture A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. NCI A finding of damage to the ankle joint characterized by a break in the continuity of the ankle bone. Symptoms include marked discomfort, swelling and difficulty moving the affected leg and foot. CTCAE_v5 Ankle Fracture, CTCAE PT NCI Ankle fracture PT CTCAE_v5 ctcae5:C143285 A disorder characterized by an infectious process involving the anal area and the rectum. A disorder characterized by an infectious process involving the anal area and the rectum. Anorectal Infection, CTCAE Anorectal infection 10061640 C143285 Anorectal infection Anorectal infection A disorder characterized by an infectious process involving the anal area and the rectum. NCI A disorder characterized by an infectious process involving the anal area and the rectum. CTCAE_v5 Anorectal Infection, CTCAE PT NCI Anorectal infection PT CTCAE_v5 ctcae5:C143287 A disorder characterized by an inability to achieve orgasm. A disorder characterized by an inability to achieve orgasm. Anorgasmia Anorgasmia, CTCAE 10002652 C143287 Anorgasmia Anorgasmia A disorder characterized by an inability to achieve orgasm. NCI A disorder characterized by an inability to achieve orgasm. CTCAE_v5 Anorgasmia PT CTCAE_v5 Anorgasmia, CTCAE PT NCI ctcae5:C143289 A finding of damage to the aorta. A finding of damage to the aorta. Aortic Injury, CTCAE Aortic injury 10002899 C143289 Aortic injury Aortic injury A finding of damage to the aorta. NCI A finding of damage to the aorta. CTCAE_v5 Aortic Injury, CTCAE PT NCI Aortic injury PT CTCAE_v5 ctcae5:C143290 A disorder characterized by a defect in aortic valve function or structure. A disorder characterized by a defect in aortic valve function or structure. Aortic Valve Disease, CTCAE Aortic valve disease 10061589 C143290 Aortic valve disease Aortic valve disease A disorder characterized by a defect in aortic valve function or structure. NCI A disorder characterized by a defect in aortic valve function or structure. CTCAE_v5 Aortic Valve Disease, CTCAE PT NCI Aortic valve disease PT CTCAE_v5 ctcae5:C143291 A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). Aphonia Aphonia, CTCAE 10002953 C143291 Aphonia Aphonia A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). NCI A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functional (psychogenic). CTCAE_v5 Aphonia PT CTCAE_v5 Aphonia, CTCAE PT NCI ctcae5:C143293 A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. Appendicitis Perforated, CTCAE Appendicitis perforated 10003012 C143293 Appendicitis perforated Appendicitis perforated A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. NCI A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent with gangrenous changes resulting in the rupture of the appendiceal wall. The appendiceal wall rupture causes the release of inflammatory and bacterial contents from the appendiceal lumen into the abdominal cavity. CTCAE_v5 Appendicitis Perforated, CTCAE PT NCI Appendicitis perforated PT CTCAE_v5 ctcae5:C143294 A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. Appendicitis Appendicitis, CTCAE 10003011 C143294 Appendicitis Appendicitis A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. NCI A disorder characterized by acute inflammation to the vermiform appendix caused by a pathogenic agent. CTCAE_v5 Appendicitis PT CTCAE_v5 Appendicitis, CTCAE PT NCI ctcae5:C143295 A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. Arachnoiditis Arachnoiditis, CTCAE 10003074 C143295 Arachnoiditis Arachnoiditis A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. NCI A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space. CTCAE_v5 Arachnoiditis PT CTCAE_v5 Arachnoiditis, CTCAE PT NCI ctcae5:C143296 A finding of damage to an artery. A finding of damage to an artery. Arterial Injury, CTCAE Arterial injury 10003162 C143296 Arterial injury Arterial injury A finding of damage to an artery. NCI A finding of damage to an artery. CTCAE_v5 Arterial Injury, CTCAE PT NCI Arterial injury PT CTCAE_v5 ctcae5:C143297 A disorder characterized by an infectious process involving an artery. A disorder characterized by an infectious process involving an artery. Arteritis Infective, CTCAE Arteritis infective 10065744 C143297 Arteritis infective Arteritis infective A disorder characterized by an infectious process involving an artery. NCI A disorder characterized by an infectious process involving an artery. CTCAE_v5 Arteritis Infective, CTCAE PT NCI Arteritis infective PT CTCAE_v5 ctcae5:C143298 A disorder characterized by a sensation of marked discomfort in a joint. A disorder characterized by a sensation of marked discomfort in a joint. Arthralgia Arthralgia, CTCAE 10003239 C143298 Arthralgia Arthralgia A disorder characterized by a sensation of marked discomfort in a joint. NCI A disorder characterized by a sensation of marked discomfort in a joint. CTCAE_v5 Arthralgia PT CTCAE_v5 Arthralgia, CTCAE PT NCI ctcae5:C143299 A disorder characterized by inflammation involving a joint. A disorder characterized by inflammation involving a joint. Arthritis Arthritis, CTCAE 10003246 C143299 Arthritis Arthritis A disorder characterized by inflammation involving a joint. NCI A disorder characterized by inflammation involving a joint. CTCAE_v5 Arthritis PT CTCAE_v5 Arthritis, CTCAE PT NCI ctcae5:C143300 A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. Ascites Ascites, CTCAE 10003445 C143300 Ascites Ascites A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. NCI A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity. CTCAE_v5 Ascites PT CTCAE_v5 Ascites, CTCAE PT NCI ctcae5:C143301 A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. Aspartate Aminotransferase Increased, CTCAE Aspartate aminotransferase increased 10003481 C143301 Aspartate aminotransferase increased Aspartate aminotransferase increased A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. NCI A finding based on laboratory test results that indicate an increase in the level of aspartate aminotransferase (AST or SGOT) in a blood specimen. CTCAE_v5 Aspartate Aminotransferase Increased, CTCAE PT NCI Aspartate aminotransferase increased PT CTCAE_v5 ctcae5:C143308 A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. Atrioventricular Block Complete, CTCAE Atrioventricular block complete 10003673 C143308 Atrioventricular block complete Atrioventricular block complete A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. NCI A disorder characterized by a dysrhythmia with complete failure of atrial electrical impulse conduction through the AV node to the ventricles. CTCAE_v5 Atrioventricular Block Complete, CTCAE PT NCI Atrioventricular block complete PT CTCAE_v5 ctcae5:C143309 A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. Atrioventricular Block First Degree, CTCAE Atrioventricular block first degree 10003674 C143309 Atrioventricular block first degree Atrioventricular block first degree A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. NCI A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. CTCAE_v5 Atrioventricular Block First Degree, CTCAE PT NCI Atrioventricular block first degree PT CTCAE_v5 ctcae5:C143310 A disorder characterized by loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. A disorder characterized by loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. Autoimmune Disorder, CTCAE Autoimmune disorder 10061664 C143310 Autoimmune disorder Autoimmune disorder A disorder characterized by loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. NCI A disorder characterized by loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. CTCAE_v5 Autoimmune Disorder, CTCAE PT NCI Autoimmune disorder PT CTCAE_v5 ctcae5:C143311 A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. Avascular Necrosis, CTCAE Avascular necrosis 10066480 C143311 Avascular necrosis Avascular necrosis A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. NCI A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure. CTCAE_v5 Avascular Necrosis, CTCAE PT NCI Avascular necrosis PT CTCAE_v5 ctcae5:C143312 A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. Azoospermia Azoospermia, CTCAE 10003883 C143312 Azoospermia Azoospermia A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. NCI A disorder characterized by laboratory test results that indicate complete absence of spermatozoa in the semen. CTCAE_v5 Azoospermia PT CTCAE_v5 Azoospermia, CTCAE PT NCI ctcae5:C143314 A disorder characterized by a narrowing of the lumen of the bile duct. A disorder characterized by a narrowing of the lumen of the bile duct. Bile Duct Stenosis, CTCAE Bile duct stenosis 10051341 C143314 Bile duct stenosis Bile duct stenosis A disorder characterized by a narrowing of the lumen of the bile duct. NCI A disorder characterized by a narrowing of the lumen of the bile duct. CTCAE_v5 Bile Duct Stenosis, CTCAE PT NCI Bile duct stenosis PT CTCAE_v5 ctcae5:C143315 A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). Biliary Anastomotic Leak, CTCAE Biliary anastomotic leak 10050458 C143315 Biliary anastomotic leak Biliary anastomotic leak A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage of bile due to breakdown of a biliary anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Biliary Anastomotic Leak, CTCAE PT NCI Biliary anastomotic leak PT CTCAE_v5 ctcae5:C143316 A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. Biliary Fistula, CTCAE Biliary fistula 10004665 C143316 Biliary fistula Biliary fistula A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the bile ducts and another organ or anatomic site. CTCAE_v5 Biliary Fistula, CTCAE PT NCI Biliary fistula PT CTCAE_v5 ctcae5:C143317 A disorder characterized by an infectious process involving the biliary tract. A disorder characterized by an infectious process involving the biliary tract. Biliary Tract Infection, CTCAE Biliary tract infection 10061695 C143317 Biliary tract infection Biliary tract infection A disorder characterized by an infectious process involving the biliary tract. NCI A disorder characterized by an infectious process involving the biliary tract. CTCAE_v5 Biliary Tract Infection, CTCAE PT NCI Biliary tract infection PT CTCAE_v5 ctcae5:C143318 A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). Bladder Anastomotic Leak, CTCAE Bladder anastomotic leak 10065802 C143318 Bladder anastomotic leak Bladder anastomotic leak A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage of urine due to breakdown of a bladder anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Bladder Anastomotic Leak, CTCAE PT NCI Bladder anastomotic leak PT CTCAE_v5 ctcae5:C143319 A disorder characterized by an infectious process involving the bladder. A disorder characterized by an infectious process involving the bladder. Bladder Infection, CTCAE Bladder infection 10005047 C143319 Bladder infection Bladder infection A disorder characterized by an infectious process involving the bladder. NCI A disorder characterized by an infectious process involving the bladder. CTCAE_v5 Bladder Infection, CTCAE PT NCI Bladder infection PT CTCAE_v5 ctcae5:C143322 A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. Bloating Bloating, CTCAE 10005265 C143322 Bloating Bloating A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. NCI A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen. CTCAE_v5 Bloating PT CTCAE_v5 Bloating, CTCAE PT NCI ctcae5:C143323 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Blood and lymphatic system disorders - Other, specify 10005329 C143323 Blood and lymphatic system disorders - Other, specify Blood and lymphatic system disorders - Other, specify Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C143324 A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. Blood Antidiuretic Hormone Abnormal, CTCAE Blood antidiuretic hormone abnormal 10005332 C143324 Blood antidiuretic hormone abnormal Blood antidiuretic hormone abnormal A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. NCI A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood specimen. CTCAE_v5 Blood Antidiuretic Hormone Abnormal, CTCAE PT NCI Blood antidiuretic hormone abnormal PT CTCAE_v5 ctcae5:C143325 A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. Blood Bilirubin Increased, CTCAE Blood bilirubin increased 10005364 C143325 Blood bilirubin increased Blood bilirubin increased A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. NCI A finding based on laboratory test results that indicate an abnormally high level of bilirubin in the blood. Excess bilirubin is associated with jaundice. CTCAE_v5 Blood Bilirubin Increased, CTCAE PT NCI Blood bilirubin increased PT CTCAE_v5 ctcae5:C143326 A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. Blood Corticotrophin Decreased, CTCAE Blood corticotrophin decreased 10005452 C143326 Blood corticotrophin decreased Blood corticotrophin decreased A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. NCI A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specimen. CTCAE_v5 Blood Corticotrophin Decreased, CTCAE PT NCI Blood corticotrophin decreased PT CTCAE_v5 ctcae5:C143327 A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. Blood Gonadotrophin Abnormal, CTCAE Blood gonadotrophin abnormal 10005561 C143327 Blood gonadotrophin abnormal Blood gonadotrophin abnormal A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. NCI A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood specimen. CTCAE_v5 Blood Gonadotrophin Abnormal, CTCAE PT NCI Blood gonadotrophin abnormal PT CTCAE_v5 ctcae5:C143328 A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. Blood Prolactin Abnormal, CTCAE Blood prolactin abnormal 10005778 C143328 Blood prolactin abnormal Blood prolactin abnormal A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. NCI A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specimen. CTCAE_v5 Blood Prolactin Abnormal, CTCAE PT NCI Blood prolactin abnormal PT CTCAE_v5 ctcae5:C143330 A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. Body Odor, CTCAE Body odor 10005901 C143330 Body odor Body odor A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. NCI A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body. CTCAE_v5 Body Odor, CTCAE PT NCI Body odor PT CTCAE_v5 ctcae5:C143331 A disorder characterized by an infectious process involving the bones. A disorder characterized by an infectious process involving the bones. Bone Infection, CTCAE Bone infection 10061017 C143331 Bone infection Bone infection A disorder characterized by an infectious process involving the bones. NCI A disorder characterized by an infectious process involving the bones. CTCAE_v5 Bone Infection, CTCAE PT NCI Bone infection PT CTCAE_v5 ctcae5:C143332 A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. Bone Marrow Hypocellular, CTCAE Bone marrow hypocellular 10048580 C143332 Bone marrow hypocellular Bone marrow hypocellular A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. NCI A disorder characterized by the inability of the bone marrow to produce hematopoietic elements. CTCAE_v5 Bone Marrow Hypocellular, CTCAE PT NCI Bone marrow hypocellular PT CTCAE_v5 ctcae5:C143335 A disorder characterized by underdevelopment of the breast. A disorder characterized by underdevelopment of the breast. Breast Atrophy, CTCAE Breast atrophy 10006179 C143335 Breast atrophy Breast atrophy A disorder characterized by underdevelopment of the breast. NCI A disorder characterized by underdevelopment of the breast. CTCAE_v5 Breast Atrophy, CTCAE PT NCI Breast atrophy PT CTCAE_v5 ctcae5:C143336 A disorder characterized by an infectious process involving the breast. A disorder characterized by an infectious process involving the breast. Breast Infection, CTCAE Breast infection 10006259 C143336 Breast infection Breast infection A disorder characterized by an infectious process involving the breast. NCI A disorder characterized by an infectious process involving the breast. CTCAE_v5 Breast Infection, CTCAE PT NCI Breast infection PT CTCAE_v5 ctcae5:C143338 A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. Bronchial Fistula, CTCAE Bronchial fistula 10006437 C143338 Bronchial fistula Bronchial fistula A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the bronchus and another organ or anatomic site. CTCAE_v5 Bronchial Fistula, CTCAE PT NCI Bronchial fistula PT CTCAE_v5 ctcae5:C143339 A disorder characterized by an infectious process involving the bronchi. A disorder characterized by an infectious process involving the bronchi. Bronchial Infection, CTCAE Bronchial infection 10055078 C143339 Bronchial infection Bronchial infection A disorder characterized by an infectious process involving the bronchi. NCI A disorder characterized by an infectious process involving the bronchi. CTCAE_v5 Bronchial Infection, CTCAE PT NCI Bronchial infection PT CTCAE_v5 ctcae5:C143340 A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. Bronchial Obstruction, CTCAE Bronchial obstruction 10006440 C143340 Bronchial obstruction Bronchial obstruction A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. NCI A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates. CTCAE_v5 Bronchial Obstruction, CTCAE PT NCI Bronchial obstruction PT CTCAE_v5 ctcae5:C143341 A disorder characterized by a narrowing of the bronchial tube. A disorder characterized by a narrowing of the bronchial tube. Bronchial Stricture, CTCAE Bronchial stricture 10063524 C143341 Bronchial stricture Bronchial stricture A disorder characterized by a narrowing of the bronchial tube. NCI A disorder characterized by a narrowing of the bronchial tube. CTCAE_v5 Bronchial Stricture, CTCAE PT NCI Bronchial stricture PT CTCAE_v5 ctcae5:C143342 A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. Bronchopleural Fistula, CTCAE Bronchopleural fistula 10053481 C143342 Bronchopleural fistula Bronchopleural fistula A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. NCI A disorder characterized by an abnormal communication between a bronchus and the pleural cavity. CTCAE_v5 Bronchopleural Fistula, CTCAE PT NCI Bronchopleural fistula PT CTCAE_v5 ctcae5:C143343 A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. Bronchopulmonary Hemorrhage, CTCAE Bronchopulmonary hemorrhage 10065746 C143343 Bronchopulmonary hemorrhage Bronchopulmonary hemorrhage A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. NCI A disorder characterized by bleeding from the bronchial wall and/or lung parenchyma. CTCAE_v5 Bronchopulmonary Hemorrhage, CTCAE PT NCI Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C143344 A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. Bronchospasm Bronchospasm, CTCAE 10006482 C143344 Bronchospasm Bronchospasm A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. NCI A disorder characterized by a sudden contraction of the smooth muscles of the bronchial wall. CTCAE_v5 Bronchospasm PT CTCAE_v5 Bronchospasm, CTCAE PT NCI ctcae5:C143345 A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. Bruising Bruising, CTCAE 10006504 C143345 Bruising Bruising A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. NCI A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues. CTCAE_v5 Bruising PT CTCAE_v5 Bruising, CTCAE PT NCI ctcae5:C143346 A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. Bullous Dermatitis, CTCAE Bullous dermatitis 10006556 C143346 Bullous dermatitis Bullous dermatitis A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. NCI A disorder characterized by inflammation of the skin characterized by the presence of bullae which are filled with fluid. CTCAE_v5 Bullous Dermatitis, CTCAE PT NCI Bullous dermatitis PT CTCAE_v5 ctcae5:C143349 A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. Capillary Leak Syndrome, CTCAE Capillary leak syndrome 10007196 C143349 Capillary leak syndrome Capillary leak syndrome A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. NCI A disorder characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. CTCAE_v5 Capillary Leak Syndrome, CTCAE PT NCI Capillary leak syndrome PT CTCAE_v5 ctcae5:C143350 A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. Carbon Monoxide Diffusing Capacity Decreased, CTCAE Carbon monoxide diffusing capacity decreased 10065906 C143350 Carbon monoxide diffusing capacity decreased Carbon monoxide diffusing capacity decreased A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. NCI A finding based on lung function test results that indicate a decrease in the lung capacity to absorb carbon monoxide. CTCAE_v5 Carbon Monoxide Diffusing Capacity Decreased, CTCAE PT NCI Carbon monoxide diffusing capacity decreased PT CTCAE_v5 ctcae5:C143351 A disorder characterized by cessation of the pumping function of the heart. A disorder characterized by cessation of the pumping function of the heart. Cardiac Arrest, CTCAE Cardiac arrest 10007515 C143351 Cardiac arrest Cardiac arrest A disorder characterized by cessation of the pumping function of the heart. NCI A disorder characterized by cessation of the pumping function of the heart. CTCAE_v5 Cardiac Arrest, CTCAE PT NCI Cardiac arrest PT CTCAE_v5 ctcae5:C143352 Cardiac Disorders - Other, Specify, CTCAE Cardiac disorders - Other, specify 10007541 C143352 Cardiac disorders - Other, specify Cardiac disorders - Other, specify Cardiac Disorders - Other, Specify, CTCAE PT NCI Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C143353 A finding based on laboratory test results that indicate increased levels of cardiac troponin I in a biological specimen. A finding based on laboratory test results that indicate increased levels of cardiac troponin I in a biological specimen. Cardiac Troponin I Increased, CTCAE Cardiac troponin I increased 10007612 C143353 Cardiac troponin I increased Cardiac troponin I increased A finding based on laboratory test results that indicate increased levels of cardiac troponin I in a biological specimen. NCI A finding based on laboratory test results that indicate increased levels of cardiac troponin I in a biological specimen. CTCAE_v5 Cardiac Troponin I Increased, CTCAE PT NCI Cardiac troponin I increased PT CTCAE_v5 ctcae5:C143354 A finding based on laboratory test results that indicate increased levels of cardiac troponin T in a biological specimen. A finding based on laboratory test results that indicate increased levels of cardiac troponin T in a biological specimen. Cardiac Troponin T Increased, CTCAE Cardiac troponin T increased 10007613 C143354 Cardiac troponin T increased Cardiac troponin T increased A finding based on laboratory test results that indicate increased levels of cardiac troponin T in a biological specimen. NCI A finding based on laboratory test results that indicate increased levels of cardiac troponin T in a biological specimen. CTCAE_v5 Cardiac Troponin T Increased, CTCAE PT NCI Cardiac troponin T increased PT CTCAE_v5 ctcae5:C143356 A disorder characterized by an infectious process that arises secondary to catheter use. A disorder characterized by an infectious process that arises secondary to catheter use. Catheter Related Infection, CTCAE Catheter related infection 10007810 C143356 Catheter related infection Catheter related infection A disorder characterized by an infectious process that arises secondary to catheter use. NCI A disorder characterized by an infectious process that arises secondary to catheter use. CTCAE_v5 Catheter Related Infection, CTCAE PT NCI Catheter related infection PT CTCAE_v5 ctcae5:C143357 A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. CD4 Lymphocytes Decreased, CTCAE CD4 lymphocytes decreased 10007839 C143357 CD4 lymphocytes decreased CD4 lymphocytes decreased A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. NCI A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood specimen. CTCAE_v5 CD4 Lymphocytes Decreased, CTCAE PT NCI CD4 lymphocytes decreased PT CTCAE_v5 ctcae5:C143358 A disorder characterized by bleeding from the cecum. A disorder characterized by bleeding from the cecum. Cecal Hemorrhage, CTCAE Cecal hemorrhage 10065747 C143358 Cecal hemorrhage Cecal hemorrhage A disorder characterized by bleeding from the cecum. NCI A disorder characterized by bleeding from the cecum. CTCAE_v5 Cecal Hemorrhage, CTCAE PT NCI Cecal hemorrhage PT CTCAE_v5 ctcae5:C143359 A disorder characterized by an infectious process involving the cecum. A disorder characterized by an infectious process involving the cecum. Cecal Infection, CTCAE Cecal infection 10065761 C143359 Cecal infection Cecal infection A disorder characterized by an infectious process involving the cecum. NCI A disorder characterized by an infectious process involving the cecum. CTCAE_v5 Cecal Infection, CTCAE PT NCI Cecal infection PT CTCAE_v5 ctcae5:C143360 A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. Central Nervous System Necrosis, CTCAE Central nervous system necrosis 10065784 C143360 Central nervous system necrosis Central nervous system necrosis A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. NCI A disorder characterized by a necrotic process occurring in the brain and/or spinal cord. CTCAE_v5 Central Nervous System Necrosis, CTCAE PT NCI Central nervous system necrosis PT CTCAE_v5 ctcae5:C143361 A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. Cerebrospinal Fluid Leakage, CTCAE Cerebrospinal fluid leakage 10008164 C143361 Cerebrospinal fluid leakage Cerebrospinal fluid leakage A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. NCI A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues. CTCAE_v5 Cerebrospinal Fluid Leakage, CTCAE PT NCI Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C143362 A disorder characterized by an infectious process involving the uterine cervix. A disorder characterized by an infectious process involving the uterine cervix. Cervicitis Infection, CTCAE Cervicitis infection 10008330 C143362 Cervicitis infection Cervicitis infection A disorder characterized by an infectious process involving the uterine cervix. NCI A disorder characterized by an infectious process involving the uterine cervix. CTCAE_v5 Cervicitis Infection, CTCAE PT NCI Cervicitis infection PT CTCAE_v5 ctcae5:C143364 A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation e.g., angina pectoris. A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation e.g., angina pectoris. Chest Pain - Cardiac, CTCAE Chest pain - cardiac 10008481 C143364 Chest pain - cardiac Chest pain - cardiac A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation e.g., angina pectoris. NCI A disorder characterized by substernal discomfort due to insufficient myocardial oxygenation e.g., angina pectoris. CTCAE_v5 Chest Pain - Cardiac, CTCAE PT NCI Chest pain - cardiac PT CTCAE_v5 ctcae5:C143366 A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. Chills Chills, CTCAE 10008531 C143366 Chills Chills A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. NCI A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. CTCAE_v5 Chills PT CTCAE_v5 Chills, CTCAE PT NCI ctcae5:C143368 A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. Cholesterol High, CTCAE Cholesterol high 10008661 C143368 Cholesterol high Cholesterol high A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. NCI A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood specimen. CTCAE_v5 Cholesterol High, CTCAE PT NCI Cholesterol high PT CTCAE_v5 ctcae5:C143369 A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. Chronic Kidney Disease, CTCAE Chronic kidney disease 10064848 C143369 Chronic kidney disease Chronic kidney disease A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. NCI A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure. CTCAE_v5 Chronic Kidney Disease, CTCAE PT NCI Chronic kidney disease PT CTCAE_v5 ctcae5:C143373 A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. Colonic Fistula, CTCAE Colonic fistula 10009995 C143373 Colonic fistula Colonic fistula A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the large intestine and another organ or anatomic site. CTCAE_v5 Colonic Fistula, CTCAE PT NCI Colonic fistula PT CTCAE_v5 ctcae5:C143374 A disorder characterized by bleeding from the colon. A disorder characterized by bleeding from the colon. Colonic Hemorrhage, CTCAE Colonic hemorrhage 10009998 C143374 Colonic hemorrhage Colonic hemorrhage A disorder characterized by bleeding from the colon. NCI A disorder characterized by bleeding from the colon. CTCAE_v5 Colonic Hemorrhage, CTCAE PT NCI Colonic hemorrhage PT CTCAE_v5 ctcae5:C143375 A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. Colonic Obstruction, CTCAE Colonic obstruction 10010000 C143375 Colonic obstruction Colonic obstruction A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. NCI A disorder characterized by blockage of the normal flow of the intestinal contents in the colon. CTCAE_v5 Colonic Obstruction, CTCAE PT NCI Colonic obstruction PT CTCAE_v5 ctcae5:C143376 A disorder characterized by a rupture in the colonic wall. A disorder characterized by a rupture in the colonic wall. Colonic Perforation, CTCAE Colonic perforation 10010001 C143376 Colonic perforation Colonic perforation A disorder characterized by a rupture in the colonic wall. NCI A disorder characterized by a rupture in the colonic wall. CTCAE_v5 Colonic Perforation, CTCAE PT NCI Colonic perforation PT CTCAE_v5 ctcae5:C143377 A disorder characterized by a narrowing of the lumen of the colon. A disorder characterized by a narrowing of the lumen of the colon. Colonic Stenosis, CTCAE Colonic stenosis 10010004 C143377 Colonic stenosis Colonic stenosis A disorder characterized by a narrowing of the lumen of the colon. NCI A disorder characterized by a narrowing of the lumen of the colon. CTCAE_v5 Colonic Stenosis, CTCAE PT NCI Colonic stenosis PT CTCAE_v5 ctcae5:C143378 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the colon. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the colon. Colonic Ulcer, CTCAE Colonic ulcer 10010006 C143378 Colonic ulcer Colonic ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the colon. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the colon. CTCAE_v5 Colonic Ulcer, CTCAE PT NCI Colonic ulcer PT CTCAE_v5 ctcae5:C143379 A disorder characterized by a deterioration in the ability to concentrate. A disorder characterized by a deterioration in the ability to concentrate. Concentration Impairment, CTCAE Concentration impairment 10010250 C143379 Concentration impairment Concentration impairment A disorder characterized by a deterioration in the ability to concentrate. NCI A disorder characterized by a deterioration in the ability to concentrate. CTCAE_v5 Concentration Impairment, CTCAE PT NCI Concentration impairment PT CTCAE_v5 ctcae5:C143380 A disorder characterized by pathological irregularities in the cardiac conduction system. A disorder characterized by pathological irregularities in the cardiac conduction system. Conduction Disorder, CTCAE Conduction disorder 10010276 C143380 Conduction disorder Conduction disorder A disorder characterized by pathological irregularities in the cardiac conduction system. NCI A disorder characterized by pathological irregularities in the cardiac conduction system. CTCAE_v5 Conduction Disorder, CTCAE PT NCI Conduction disorder PT CTCAE_v5 ctcae5:C143382 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Congenital, familial and genetic disorders - Other, specify 10010331 C143382 Congenital, familial and genetic disorders - Other, specify Congenital, familial and genetic disorders - Other, specify Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C143383 A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. Conjunctivitis Infective, CTCAE Conjunctivitis infective 10010742 C143383 Conjunctivitis infective Conjunctivitis infective A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. NCI A disorder characterized by an infectious process involving the conjunctiva. Clinical manifestations include pink or red color in the eyes. CTCAE_v5 Conjunctivitis Infective, CTCAE PT NCI Conjunctivitis infective PT CTCAE_v5 ctcae5:C143384 A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. Conjunctivitis Conjunctivitis, CTCAE 10010741 C143384 Conjunctivitis Conjunctivitis A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. NCI A disorder characterized by inflammation, swelling and redness to the conjunctiva of the eye. CTCAE_v5 Conjunctivitis PT CTCAE_v5 Conjunctivitis, CTCAE PT NCI ctcae5:C143386 A disorder characterized by an infectious process involving the cornea. A disorder characterized by an infectious process involving the cornea. Corneal Infection, CTCAE Corneal infection 10061788 C143386 Corneal infection Corneal infection A disorder characterized by an infectious process involving the cornea. NCI A disorder characterized by an infectious process involving the cornea. CTCAE_v5 Corneal Infection, CTCAE PT NCI Corneal infection PT CTCAE_v5 ctcae5:C143387 A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. Corneal Ulcer, CTCAE Corneal ulcer 10048492 C143387 Corneal ulcer Corneal ulcer A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. NCI A disorder characterized by an area of epithelial tissue loss on the surface of the cornea. It is associated with inflammatory cells in the cornea and anterior chamber. CTCAE_v5 Corneal Ulcer, CTCAE PT NCI Corneal ulcer PT CTCAE_v5 ctcae5:C143389 A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. CPK Increased, CTCAE CPK increased 10011268 C143389 CPK increased CPK increased A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. NCI A finding based on laboratory test results that indicate an increase in levels of creatine phosphokinase in a blood specimen. CTCAE_v5 CPK Increased, CTCAE PT NCI CPK increased PT CTCAE_v5 ctcae5:C143390 A disorder characterized by an infectious process involving a cranial nerve. A disorder characterized by an infectious process involving a cranial nerve. Cranial Nerve Infection, CTCAE Cranial nerve infection 10065765 C143390 Cranial nerve infection Cranial nerve infection A disorder characterized by an infectious process involving a cranial nerve. NCI A disorder characterized by an infectious process involving a cranial nerve. CTCAE_v5 Cranial Nerve Infection, CTCAE PT NCI Cranial nerve infection PT CTCAE_v5 ctcae5:C143391 A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. Creatinine Increased, CTCAE Creatinine increased 10011368 C143391 Creatinine increased Creatinine increased A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. NCI A finding based on laboratory test results that indicate increased levels of creatinine in a biological specimen. CTCAE_v5 Creatinine Increased, CTCAE PT NCI Creatinine increased PT CTCAE_v5 ctcae5:C143392 A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. Cushingoid Cushingoid, CTCAE 10011655 C143392 Cushingoid Cushingoid A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. NCI A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticosteroids. CTCAE_v5 Cushingoid PT CTCAE_v5 Cushingoid, CTCAE PT NCI ctcae5:C143393 A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. Cystitis Noninfective, CTCAE Cystitis noninfective 10063057 C143393 Cystitis noninfective Cystitis noninfective A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. NCI A disorder characterized by inflammation of the bladder which is not caused by an infection of the urinary tract. CTCAE_v5 Cystitis Noninfective, CTCAE PT NCI Cystitis noninfective PT CTCAE_v5 ctcae5:C143394 A disorder characterized by fever, tachypnea, headache, tachycardia, hypotension, rash, and/or hypoxia caused by the release of cytokines. A disorder characterized by fever, tachypnea, headache, tachycardia, hypotension, rash, and/or hypoxia caused by the release of cytokines. Cytokine Release Syndrome, CTCAE Cytokine release syndrome 10052015 C143394 Cytokine release syndrome Cytokine release syndrome A disorder characterized by fever, tachypnea, headache, tachycardia, hypotension, rash, and/or hypoxia caused by the release of cytokines. NCI A disorder characterized by fever, tachypnea, headache, tachycardia, hypotension, rash, and/or hypoxia caused by the release of cytokines. CTCAE_v5 Cytokine Release Syndrome, CTCAE PT NCI Cytokine release syndrome PT CTCAE_v5 ctcae5:C143395 Newborn death occurring during the first 28 days after birth. Newborn death occurring during the first 28 days after birth. Death Neonatal, CTCAE Death neonatal 10011912 C143395 Death neonatal Death neonatal Newborn death occurring during the first 28 days after birth. NCI Newborn death occurring during the first 28 days after birth. CTCAE_v5 Death Neonatal, CTCAE PT NCI Death neonatal PT CTCAE_v5 ctcae5:C143396 Death that cannot be attributed to a CTCAE term associated with Grade 5. Death that cannot be attributed to a CTCAE term associated with Grade 5. Death NOS Death NOS, CTCAE 10011914 C143396 Death NOS Death NOS Death that cannot be attributed to a CTCAE term associated with Grade 5. NCI Death that cannot be attributed to a CTCAE term associated with Grade 5. CTCAE_v5 Death NOS PT CTCAE_v5 Death NOS, CTCAE PT NCI ctcae5:C143398 A disorder characterized by sexual dysfunction characterized by a delay in climax. A disorder characterized by sexual dysfunction characterized by a delay in climax. Delayed Orgasm, CTCAE Delayed orgasm 10057066 C143398 Delayed orgasm Delayed orgasm A disorder characterized by sexual dysfunction characterized by a delay in climax. NCI A disorder characterized by sexual dysfunction characterized by a delay in climax. CTCAE_v5 Delayed Orgasm, CTCAE PT NCI Delayed orgasm PT CTCAE_v5 ctcae5:C143400 A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. Delirium Delirium, CTCAE 10012218 C143400 Delirium Delirium A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. NCI A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. CTCAE_v5 Delirium PT CTCAE_v5 Delirium, CTCAE PT NCI ctcae5:C143401 A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. Delusions Delusions, CTCAE 10012260 C143401 Delusions Delusions A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. NCI A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense. CTCAE_v5 Delusions PT CTCAE_v5 Delusions, CTCAE PT NCI ctcae5:C143402 A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. Dental Caries, CTCAE Dental caries 10012318 C143402 Dental caries Dental caries A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. NCI A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. CTCAE_v5 Dental Caries, CTCAE PT NCI Dental caries PT CTCAE_v5 ctcae5:C143403 A disorder characterized by a decrease in ability to perceive and respond. A disorder characterized by a decrease in ability to perceive and respond. Depressed Level of Consciousness, CTCAE Depressed level of consciousness 10012373 C143403 Depressed level of consciousness Depressed level of consciousness A disorder characterized by a decrease in ability to perceive and respond. NCI A disorder characterized by a decrease in ability to perceive and respond. CTCAE_v5 Depressed Level of Consciousness, CTCAE PT NCI Depressed level of consciousness PT CTCAE_v5 ctcae5:C143405 A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. Dermatitis Radiation, CTCAE Dermatitis radiation 10061103 C143405 Dermatitis radiation Dermatitis radiation A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. NCI A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. CTCAE_v5 Dermatitis Radiation, CTCAE PT NCI Dermatitis radiation PT CTCAE_v5 ctcae5:C143406 A disorder characterized by an infectious process involving the use of a medical device. A disorder characterized by an infectious process involving the use of a medical device. Device Related Infection, CTCAE Device related infection 10064687 C143406 Device related infection Device related infection A disorder characterized by an infectious process involving the use of a medical device. NCI A disorder characterized by an infectious process involving the use of a medical device. CTCAE_v5 Device Related Infection, CTCAE PT NCI Device related infection PT CTCAE_v5 ctcae5:C143410 A disorder characterized by dryness of the cornea and conjunctiva. A disorder characterized by dryness of the cornea and conjunctiva. Dry Eye, CTCAE Dry eye 10013774 C143410 Dry eye Dry eye A disorder characterized by dryness of the cornea and conjunctiva. NCI A disorder characterized by dryness of the cornea and conjunctiva. CTCAE_v5 Dry Eye, CTCAE PT NCI Dry eye PT CTCAE_v5 ctcae5:C143411 A disorder characterized by reduced salivary flow in the oral cavity. A disorder characterized by reduced salivary flow in the oral cavity. Dry Mouth, CTCAE Dry mouth 10013781 C143411 Dry mouth Dry mouth A disorder characterized by reduced salivary flow in the oral cavity. NCI A disorder characterized by reduced salivary flow in the oral cavity. CTCAE_v5 Dry Mouth, CTCAE PT NCI Dry mouth PT CTCAE_v5 ctcae5:C143414 A disorder characterized by bleeding from the duodenum. A disorder characterized by bleeding from the duodenum. Duodenal Hemorrhage, CTCAE Duodenal hemorrhage 10055242 C143414 Duodenal hemorrhage Duodenal hemorrhage A disorder characterized by bleeding from the duodenum. NCI A disorder characterized by bleeding from the duodenum. CTCAE_v5 Duodenal Hemorrhage, CTCAE PT NCI Duodenal hemorrhage PT CTCAE_v5 ctcae5:C143415 A disorder characterized by an infectious process involving the duodenum. A disorder characterized by an infectious process involving the duodenum. Duodenal Infection, CTCAE Duodenal infection 10065752 C143415 Duodenal infection Duodenal infection A disorder characterized by an infectious process involving the duodenum. NCI A disorder characterized by an infectious process involving the duodenum. CTCAE_v5 Duodenal Infection, CTCAE PT NCI Duodenal infection PT CTCAE_v5 ctcae5:C143416 A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. Duodenal Obstruction, CTCAE Duodenal obstruction 10013830 C143416 Duodenal obstruction Duodenal obstruction A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. NCI A disorder characterized by blockage of the normal flow of stomach contents through the duodenum. CTCAE_v5 Duodenal Obstruction, CTCAE PT NCI Duodenal obstruction PT CTCAE_v5 ctcae5:C143417 A disorder characterized by a rupture in the duodenal wall. A disorder characterized by a rupture in the duodenal wall. Duodenal Perforation, CTCAE Duodenal perforation 10013832 C143417 Duodenal perforation Duodenal perforation A disorder characterized by a rupture in the duodenal wall. NCI A disorder characterized by a rupture in the duodenal wall. CTCAE_v5 Duodenal Perforation, CTCAE PT NCI Duodenal perforation PT CTCAE_v5 ctcae5:C143418 A disorder characterized by a narrowing of the lumen of the duodenum. A disorder characterized by a narrowing of the lumen of the duodenum. Duodenal Stenosis, CTCAE Duodenal stenosis 10050094 C143418 Duodenal stenosis Duodenal stenosis A disorder characterized by a narrowing of the lumen of the duodenum. NCI A disorder characterized by a narrowing of the lumen of the duodenum. CTCAE_v5 Duodenal Stenosis, CTCAE PT NCI Duodenal stenosis PT CTCAE_v5 ctcae5:C143419 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the duodenal wall. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the duodenal wall. Duodenal Ulcer, CTCAE Duodenal ulcer 10013836 C143419 Duodenal ulcer Duodenal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the duodenal wall. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the duodenal wall. CTCAE_v5 Duodenal Ulcer, CTCAE PT NCI Duodenal ulcer PT CTCAE_v5 ctcae5:C143420 A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. Dysarthria Dysarthria, CTCAE 10013887 C143420 Dysarthria Dysarthria A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. NCI A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used in speech. CTCAE_v5 Dysarthria PT CTCAE_v5 Dysarthria, CTCAE PT NCI ctcae5:C143421 A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. Dysesthesia Dysesthesia, CTCAE 10062872 C143421 Dysesthesia Dysesthesia A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. NCI A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation. CTCAE_v5 Dysesthesia PT CTCAE_v5 Dysesthesia, CTCAE PT NCI ctcae5:C143422 A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. Dysgeusia Dysgeusia, CTCAE 10013911 C143422 Dysgeusia Dysgeusia A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. NCI A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a decrease in the sense of smell. CTCAE_v5 Dysgeusia PT CTCAE_v5 Dysgeusia, CTCAE PT NCI ctcae5:C143423 A disorder characterized by abnormally painful abdominal cramps during menses. A disorder characterized by abnormally painful abdominal cramps during menses. Dysmenorrhea Dysmenorrhea, CTCAE 10013934 C143423 Dysmenorrhea Dysmenorrhea A disorder characterized by abnormally painful abdominal cramps during menses. NCI A disorder characterized by abnormally painful abdominal cramps during menses. CTCAE_v5 Dysmenorrhea PT CTCAE_v5 Dysmenorrhea, CTCAE PT NCI ctcae5:C143424 A disorder characterized by painful or difficult coitus. A disorder characterized by painful or difficult coitus. Dyspareunia Dyspareunia, CTCAE 10013941 C143424 Dyspareunia Dyspareunia A disorder characterized by painful or difficult coitus. NCI A disorder characterized by painful or difficult coitus. CTCAE_v5 Dyspareunia PT CTCAE_v5 Dyspareunia, CTCAE PT NCI ctcae5:C143425 A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. Dyspepsia Dyspepsia, CTCAE 10013946 C143425 Dyspepsia Dyspepsia A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. NCI A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. CTCAE_v5 Dyspepsia PT CTCAE_v5 Dyspepsia, CTCAE PT NCI ctcae5:C143427 A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. Dysphasia Dysphasia, CTCAE 10013951 C143427 Dysphasia Dysphasia A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. NCI A disorder characterized by impairment of verbal communication skills, often resulting from brain damage. CTCAE_v5 Dysphasia PT CTCAE_v5 Dysphasia, CTCAE PT NCI ctcae5:C143429 Ear and Labyrinth Disorders - Other, Specify, CTCAE Ear and labyrinth disorders - Other, specify 10013993 C143429 Ear and labyrinth disorders - Other, specify Ear and labyrinth disorders - Other, specify Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C143430 A disorder characterized by a sensation of marked discomfort in the ear. A disorder characterized by a sensation of marked discomfort in the ear. Ear Pain, CTCAE Ear pain 10014020 C143430 Ear pain Ear pain A disorder characterized by a sensation of marked discomfort in the ear. NCI A disorder characterized by a sensation of marked discomfort in the ear. CTCAE_v5 Ear Pain, CTCAE PT NCI Ear pain PT CTCAE_v5 ctcae5:C143431 A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. Edema Cerebral, CTCAE Edema cerebral 10014217 C143431 Edema cerebral Edema cerebral A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. NCI A disorder characterized by swelling due to an excessive accumulation of fluid in the brain. CTCAE_v5 Edema Cerebral, CTCAE PT NCI Edema cerebral PT CTCAE_v5 ctcae5:C143432 A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. Edema Face, CTCAE Edema face 10014222 C143432 Edema face Edema face A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. NCI A disorder characterized by swelling due to excessive fluid accumulation in facial tissues. CTCAE_v5 Edema Face, CTCAE PT NCI Edema face PT CTCAE_v5 ctcae5:C143433 A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. Edema Limbs, CTCAE Edema limbs 10050068 C143433 Edema limbs Edema limbs A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. NCI A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities. CTCAE_v5 Edema Limbs, CTCAE PT NCI Edema limbs PT CTCAE_v5 ctcae5:C143434 A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. Edema Trunk, CTCAE Edema trunk 10058720 C143434 Edema trunk Edema trunk A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. NCI A disorder characterized by swelling due to excessive fluid accumulation in the trunk area. CTCAE_v5 Edema Trunk, CTCAE PT NCI Edema trunk PT CTCAE_v5 ctcae5:C143435 A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. Ejaculation Disorder, CTCAE Ejaculation disorder 10014326 C143435 Ejaculation disorder Ejaculation disorder A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. NCI A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrograde and painful ejaculation. CTCAE_v5 Ejaculation Disorder, CTCAE PT NCI Ejaculation disorder PT CTCAE_v5 ctcae5:C143436 The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. Ejection Fraction Decreased, CTCAE Ejection fraction decreased 10050528 C143436 Ejection fraction decreased Ejection fraction decreased The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. NCI The percentage computed when the amount of blood ejected during a ventricular contraction of the heart is compared to the amount that was present prior to the contraction. CTCAE_v5 Ejection Fraction Decreased, CTCAE PT NCI Ejection fraction decreased PT CTCAE_v5 ctcae5:C143437 A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. Electrocardiogram QT Corrected Interval Prolonged, CTCAE Electrocardiogram QT corrected interval prolonged 10014383 C143437 Electrocardiogram QT corrected interval prolonged Electrocardiogram QT corrected interval prolonged A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. NCI A finding of a cardiac dysrhythmia characterized by an abnormally long corrected QT interval. CTCAE_v5 Electrocardiogram QT Corrected Interval Prolonged, CTCAE PT NCI Electrocardiogram QT corrected interval prolonged PT CTCAE_v5 ctcae5:C143438 A disorder characterized by an infectious process involving the brain tissue. A disorder characterized by an infectious process involving the brain tissue. Encephalitis Infection, CTCAE Encephalitis infection 10014594 C143438 Encephalitis infection Encephalitis infection A disorder characterized by an infectious process involving the brain tissue. NCI A disorder characterized by an infectious process involving the brain tissue. CTCAE_v5 Encephalitis Infection, CTCAE PT NCI Encephalitis infection PT CTCAE_v5 ctcae5:C143439 A disorder characterized by an infectious process involving the brain and spinal cord tissues. A disorder characterized by an infectious process involving the brain and spinal cord tissues. Encephalomyelitis Infection, CTCAE Encephalomyelitis infection 10014621 C143439 Encephalomyelitis infection Encephalomyelitis infection A disorder characterized by an infectious process involving the brain and spinal cord tissues. NCI A disorder characterized by an infectious process involving the brain and spinal cord tissues. CTCAE_v5 Encephalomyelitis Infection, CTCAE PT NCI Encephalomyelitis infection PT CTCAE_v5 ctcae5:C143441 A disorder characterized by an infectious process involving the endocardial layer of the heart. A disorder characterized by an infectious process involving the endocardial layer of the heart. Endocarditis Infective, CTCAE Endocarditis infective 10014678 C143441 Endocarditis infective Endocarditis infective A disorder characterized by an infectious process involving the endocardial layer of the heart. NCI A disorder characterized by an infectious process involving the endocardial layer of the heart. CTCAE_v5 Endocarditis Infective, CTCAE PT NCI Endocarditis infective PT CTCAE_v5 ctcae5:C143442 Endocrine Disorders - Other, Specify, CTCAE Endocrine disorders - Other, specify 10014698 C143442 Endocrine disorders - Other, specify Endocrine disorders - Other, specify Endocrine Disorders - Other, Specify, CTCAE PT NCI Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C143443 A disorder characterized by an infectious process involving the internal structures of the eye. A disorder characterized by an infectious process involving the internal structures of the eye. Endophthalmitis Endophthalmitis, CTCAE 10014801 C143443 Endophthalmitis Endophthalmitis A disorder characterized by an infectious process involving the internal structures of the eye. NCI A disorder characterized by an infectious process involving the internal structures of the eye. CTCAE_v5 Endophthalmitis PT CTCAE_v5 Endophthalmitis, CTCAE PT NCI ctcae5:C143444 A disorder characterized by an infectious process involving the small and large intestines. A disorder characterized by an infectious process involving the small and large intestines. Enterocolitis Infectious, CTCAE Enterocolitis infectious 10058838 C143444 Enterocolitis infectious Enterocolitis infectious A disorder characterized by an infectious process involving the small and large intestines. NCI A disorder characterized by an infectious process involving the small and large intestines. CTCAE_v5 Enterocolitis Infectious, CTCAE PT NCI Enterocolitis infectious PT CTCAE_v5 ctcae5:C143445 A disorder characterized by inflammation of the small and large intestines. A disorder characterized by inflammation of the small and large intestines. Enterocolitis Enterocolitis, CTCAE 10014893 C143445 Enterocolitis Enterocolitis A disorder characterized by inflammation of the small and large intestines. NCI A disorder characterized by inflammation of the small and large intestines. CTCAE_v5 Enterocolitis PT CTCAE_v5 Enterocolitis, CTCAE PT NCI ctcae5:C143446 A disorder characterized by an abnormal communication between the urinary bladder and the intestine. A disorder characterized by an abnormal communication between the urinary bladder and the intestine. Enterovesical Fistula, CTCAE Enterovesical fistula 10062570 C143446 Enterovesical fistula Enterovesical fistula A disorder characterized by an abnormal communication between the urinary bladder and the intestine. NCI A disorder characterized by an abnormal communication between the urinary bladder and the intestine. CTCAE_v5 Enterovesical Fistula, CTCAE PT NCI Enterovesical fistula PT CTCAE_v5 ctcae5:C143447 A disorder characterized by bleeding from the nose. A disorder characterized by bleeding from the nose. Epistaxis Epistaxis, CTCAE 10015090 C143447 Epistaxis Epistaxis A disorder characterized by bleeding from the nose. NCI A disorder characterized by bleeding from the nose. CTCAE_v5 Epistaxis PT CTCAE_v5 Epistaxis, CTCAE PT NCI ctcae5:C143449 A disorder characterized by target lesions (a pink-red ring around a pale center). A disorder characterized by target lesions (a pink-red ring around a pale center). Erythema Multiforme, CTCAE Erythema multiforme 10015218 C143449 Erythema multiforme Erythema multiforme A disorder characterized by target lesions (a pink-red ring around a pale center). NCI A disorder characterized by target lesions (a pink-red ring around a pale center). CTCAE_v5 Erythema Multiforme, CTCAE PT NCI Erythema multiforme PT CTCAE_v5 ctcae5:C143450 A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. Erythroderma Erythroderma, CTCAE 10015277 C143450 Erythroderma Erythroderma A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. NCI A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process involves > 90% of the body surface area. CTCAE_v5 Erythroderma PT CTCAE_v5 Erythroderma, CTCAE PT NCI ctcae5:C143451 A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). Esophageal Anastomotic Leak, CTCAE Esophageal anastomotic leak 10065961 C143451 Esophageal anastomotic leak Esophageal anastomotic leak A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of an esophageal anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Esophageal Anastomotic Leak, CTCAE PT NCI Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C143453 A disorder characterized by bleeding from the esophagus. A disorder characterized by bleeding from the esophagus. Esophageal Hemorrhage, CTCAE Esophageal hemorrhage 10015384 C143453 Esophageal hemorrhage Esophageal hemorrhage A disorder characterized by bleeding from the esophagus. NCI A disorder characterized by bleeding from the esophagus. CTCAE_v5 Esophageal Hemorrhage, CTCAE PT NCI Esophageal hemorrhage PT CTCAE_v5 ctcae5:C143454 A disorder characterized by an infectious process involving the esophagus. A disorder characterized by an infectious process involving the esophagus. Esophageal Infection, CTCAE Esophageal infection 10058804 C143454 Esophageal infection Esophageal infection A disorder characterized by an infectious process involving the esophagus. NCI A disorder characterized by an infectious process involving the esophagus. CTCAE_v5 Esophageal Infection, CTCAE PT NCI Esophageal infection PT CTCAE_v5 ctcae5:C143455 A disorder characterized by a necrotic process occurring in the esophageal wall. A disorder characterized by a necrotic process occurring in the esophageal wall. Esophageal Necrosis, CTCAE Esophageal necrosis 10065727 C143455 Esophageal necrosis Esophageal necrosis A disorder characterized by a necrotic process occurring in the esophageal wall. NCI A disorder characterized by a necrotic process occurring in the esophageal wall. CTCAE_v5 Esophageal Necrosis, CTCAE PT NCI Esophageal necrosis PT CTCAE_v5 ctcae5:C143456 A disorder characterized by blockage of the normal flow of the contents in the esophagus. A disorder characterized by blockage of the normal flow of the contents in the esophagus. Esophageal Obstruction, CTCAE Esophageal obstruction 10015387 C143456 Esophageal obstruction Esophageal obstruction A disorder characterized by blockage of the normal flow of the contents in the esophagus. NCI A disorder characterized by blockage of the normal flow of the contents in the esophagus. CTCAE_v5 Esophageal Obstruction, CTCAE PT NCI Esophageal obstruction PT CTCAE_v5 ctcae5:C143457 A disorder characterized by a sensation of marked discomfort in the esophageal region. A disorder characterized by a sensation of marked discomfort in the esophageal region. Esophageal Pain, CTCAE Esophageal pain 10015388 C143457 Esophageal pain Esophageal pain A disorder characterized by a sensation of marked discomfort in the esophageal region. NCI A disorder characterized by a sensation of marked discomfort in the esophageal region. CTCAE_v5 Esophageal Pain, CTCAE PT NCI Esophageal pain PT CTCAE_v5 ctcae5:C143458 A disorder characterized by a rupture in the wall of the esophagus. A disorder characterized by a rupture in the wall of the esophagus. Esophageal Perforation, CTCAE Esophageal perforation 10055472 C143458 Esophageal perforation Esophageal perforation A disorder characterized by a rupture in the wall of the esophagus. NCI A disorder characterized by a rupture in the wall of the esophagus. CTCAE_v5 Esophageal Perforation, CTCAE PT NCI Esophageal perforation PT CTCAE_v5 ctcae5:C143459 A disorder characterized by a narrowing of the lumen of the esophagus. A disorder characterized by a narrowing of the lumen of the esophagus. Esophageal Stenosis, CTCAE Esophageal stenosis 10015448 C143459 Esophageal stenosis Esophageal stenosis A disorder characterized by a narrowing of the lumen of the esophagus. NCI A disorder characterized by a narrowing of the lumen of the esophagus. CTCAE_v5 Esophageal Stenosis, CTCAE PT NCI Esophageal stenosis PT CTCAE_v5 ctcae5:C143460 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the esophageal wall. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the esophageal wall. Esophageal Ulcer, CTCAE Esophageal ulcer 10015451 C143460 Esophageal ulcer Esophageal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the esophageal wall. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the esophageal wall. CTCAE_v5 Esophageal Ulcer, CTCAE PT NCI Esophageal ulcer PT CTCAE_v5 ctcae5:C143466 A disorder characterized by incomplete paralysis of an extraocular muscle. A disorder characterized by incomplete paralysis of an extraocular muscle. Extraocular Muscle Paresis, CTCAE Extraocular muscle paresis 10015829 C143466 Extraocular muscle paresis Extraocular muscle paresis A disorder characterized by incomplete paralysis of an extraocular muscle. NCI A disorder characterized by incomplete paralysis of an extraocular muscle. CTCAE_v5 Extraocular Muscle Paresis, CTCAE PT NCI Extraocular muscle paresis PT CTCAE_v5 ctcae5:C143467 A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. Extrapyramidal Disorder, CTCAE Extrapyramidal disorder 10015832 C143467 Extrapyramidal disorder Extrapyramidal disorder A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. NCI A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness. CTCAE_v5 Extrapyramidal Disorder, CTCAE PT NCI Extrapyramidal disorder PT CTCAE_v5 ctcae5:C143468 Eye Disorders - Other, Specify, CTCAE Eye disorders - Other, specify 10015919 C143468 Eye disorders - Other, specify Eye disorders - Other, specify Eye Disorders - Other, Specify, CTCAE PT NCI Eye disorders - Other, specify PT CTCAE_v5 ctcae5:C143469 A disorder characterized by an infectious process involving the eye. A disorder characterized by an infectious process involving the eye. Eye Infection, CTCAE Eye infection 10015929 C143469 Eye infection Eye infection A disorder characterized by an infectious process involving the eye. NCI A disorder characterized by an infectious process involving the eye. CTCAE_v5 Eye Infection, CTCAE PT NCI Eye infection PT CTCAE_v5 ctcae5:C143471 A disorder characterized by impaired eyelid function. A disorder characterized by impaired eyelid function. Eyelid Function Disorder, CTCAE Eyelid function disorder 10061145 C143471 Eyelid function disorder Eyelid function disorder A disorder characterized by impaired eyelid function. NCI A disorder characterized by impaired eyelid function. CTCAE_v5 Eyelid Function Disorder, CTCAE PT NCI Eyelid function disorder PT CTCAE_v5 ctcae5:C143472 A disorder characterized by a reduction in the strength of the facial muscles. A disorder characterized by a reduction in the strength of the facial muscles. Facial Muscle Weakness, CTCAE Facial muscle weakness 10051272 C143472 Facial muscle weakness Facial muscle weakness A disorder characterized by a reduction in the strength of the facial muscles. NCI A disorder characterized by a reduction in the strength of the facial muscles. CTCAE_v5 Facial Muscle Weakness, CTCAE PT NCI Facial muscle weakness PT CTCAE_v5 ctcae5:C143473 A disorder characterized by dysfunction of the facial nerve (seventh cranial nerve). A disorder characterized by dysfunction of the facial nerve (seventh cranial nerve). Facial Nerve Disorder, CTCAE Facial nerve disorder 10061457 C143473 Facial nerve disorder Facial nerve disorder A disorder characterized by dysfunction of the facial nerve (seventh cranial nerve). NCI A disorder characterized by dysfunction of the facial nerve (seventh cranial nerve). CTCAE_v5 Facial Nerve Disorder, CTCAE PT NCI Facial nerve disorder PT CTCAE_v5 ctcae5:C143474 A disorder characterized by a sensation of marked discomfort in the face. A disorder characterized by a sensation of marked discomfort in the face. Facial Pain, CTCAE Facial pain 10016059 C143474 Facial pain Facial pain A disorder characterized by a sensation of marked discomfort in the face. NCI A disorder characterized by a sensation of marked discomfort in the face. CTCAE_v5 Facial Pain, CTCAE PT NCI Facial pain PT CTCAE_v5 ctcae5:C143475 A finding of sudden movement downward, usually resulting in injury. A finding of sudden movement downward, usually resulting in injury. Fall Fall, CTCAE 10016173 C143475 Fall Fall A finding of sudden movement downward, usually resulting in injury. NCI A finding of sudden movement downward, usually resulting in injury. CTCAE_v5 Fall PT CTCAE_v5 Fall, CTCAE PT NCI ctcae5:C143476 A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). Fallopian Tube Anastomotic Leak, CTCAE Fallopian tube anastomotic leak 10065788 C143476 Fallopian tube anastomotic leak Fallopian tube anastomotic leak A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a fallopian tube anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C143479 A disorder characterized by shrinking of adipose tissue. A disorder characterized by shrinking of adipose tissue. Fat Atrophy, CTCAE Fat atrophy 10016241 C143479 Fat atrophy Fat atrophy A disorder characterized by shrinking of adipose tissue. NCI A disorder characterized by shrinking of adipose tissue. CTCAE_v5 Fat Atrophy, CTCAE PT NCI Fat atrophy PT CTCAE_v5 ctcae5:C143481 A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour Febrile Neutropenia, CTCAE Febrile neutropenia 10016288 C143481 Febrile neutropenia Febrile neutropenia A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour NCI A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour CTCAE_v5 Febrile Neutropenia, CTCAE PT NCI Febrile neutropenia PT CTCAE_v5 ctcae5:C143482 A disorder characterized by inability to control the escape of stool from the rectum. A disorder characterized by inability to control the escape of stool from the rectum. Fecal Incontinence, CTCAE Fecal incontinence 10016296 C143482 Fecal incontinence Fecal incontinence A disorder characterized by inability to control the escape of stool from the rectum. NCI A disorder characterized by inability to control the escape of stool from the rectum. CTCAE_v5 Fecal Incontinence, CTCAE PT NCI Fecal incontinence PT CTCAE_v5 ctcae5:C143483 A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. Feminization Acquired, CTCAE Feminization acquired 10054382 C143483 Feminization acquired Feminization acquired A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. NCI A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic factors. CTCAE_v5 Feminization Acquired, CTCAE PT NCI Feminization acquired PT CTCAE_v5 ctcae5:C143484 A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. Fetal Growth Retardation, CTCAE Fetal growth retardation 10054746 C143484 Fetal growth retardation Fetal growth retardation A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. NCI A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potential weight. CTCAE_v5 Fetal Growth Retardation, CTCAE PT NCI Fetal growth retardation PT CTCAE_v5 ctcae5:C143485 A disorder characterized by elevation of the body's temperature above the upper limit of normal. A disorder characterized by elevation of the body's temperature above the upper limit of normal. Fever Fever, CTCAE 10016558 C143485 Fever Fever A disorder characterized by elevation of the body's temperature above the upper limit of normal. NCI A disorder characterized by elevation of the body's temperature above the upper limit of normal. CTCAE_v5 Fever PT CTCAE_v5 Fever, CTCAE PT NCI ctcae5:C143486 A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. Fibrinogen Decreased, CTCAE Fibrinogen decreased 10016596 C143486 Fibrinogen decreased Fibrinogen decreased A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. NCI A finding based on laboratory test results that indicate an decrease in levels of fibrinogen in a blood specimen. CTCAE_v5 Fibrinogen Decreased, CTCAE PT NCI Fibrinogen decreased PT CTCAE_v5 ctcae5:C143487 A disorder characterized by fibrotic degeneration of the deep connective tissues. A disorder characterized by fibrotic degeneration of the deep connective tissues. Fibrosis Deep Connective Tissue, CTCAE Fibrosis deep connective tissue 10065799 C143487 Fibrosis deep connective tissue Fibrosis deep connective tissue A disorder characterized by fibrotic degeneration of the deep connective tissues. NCI A disorder characterized by fibrotic degeneration of the deep connective tissues. CTCAE_v5 Fibrosis Deep Connective Tissue, CTCAE PT NCI Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C143488 A disorder characterized by a sensation of marked discomfort on the lateral side of the body in the region below the ribs and above the hip. A disorder characterized by a sensation of marked discomfort on the lateral side of the body in the region below the ribs and above the hip. Flank Pain, CTCAE Flank pain 10016750 C143488 Flank pain Flank pain A disorder characterized by a sensation of marked discomfort on the lateral side of the body in the region below the ribs and above the hip. NCI A disorder characterized by a sensation of marked discomfort on the lateral side of the body in the region below the ribs and above the hip. CTCAE_v5 Flank Pain, CTCAE PT NCI Flank pain PT CTCAE_v5 ctcae5:C143489 A disorder characterized by a sudden or brief burst of light. A disorder characterized by a sudden or brief burst of light. Flashing Lights, CTCAE Flashing lights 10016757 C143489 Flashing lights Flashing lights A disorder characterized by a sudden or brief burst of light. NCI A disorder characterized by a sudden or brief burst of light. CTCAE_v5 Flashing Lights, CTCAE PT NCI Flashing lights PT CTCAE_v5 ctcae5:C143491 A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. Floaters Floaters, CTCAE 10016778 C143491 Floaters Floaters A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. NCI A disorder characterized by an individual seeing spots before their eyes. The spots are shadows of opaque cell fragments in the vitreous humor or lens. CTCAE_v5 Floaters PT CTCAE_v5 Floaters, CTCAE PT NCI ctcae5:C143492 A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. Flu Like Symptoms, CTCAE Flu like symptoms 10016791 C143492 Flu like symptoms Flu like symptoms A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. NCI A disorder characterized by a group of symptoms similar to those observed in patients with the flu. It includes fever, chills, body aches, malaise, loss of appetite and dry cough. CTCAE_v5 Flu Like Symptoms, CTCAE PT NCI Flu like symptoms PT CTCAE_v5 ctcae5:C143494 A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. Forced Expiratory Volume Decreased, CTCAE Forced expiratory volume decreased 10016987 C143494 Forced expiratory volume decreased Forced expiratory volume decreased A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. NCI A finding based on test results that indicate a relative decrease in the fraction of the forced vital capacity that is exhaled in a specific number of seconds. CTCAE_v5 Forced Expiratory Volume Decreased, CTCAE PT NCI Forced expiratory volume decreased PT CTCAE_v5 ctcae5:C143496 A disorder characterized by walking difficulties. A disorder characterized by walking difficulties. Gait Disturbance, CTCAE Gait disturbance 10017577 C143496 Gait disturbance Gait disturbance A disorder characterized by walking difficulties. NCI A disorder characterized by walking difficulties. CTCAE_v5 Gait Disturbance, CTCAE PT NCI Gait disturbance PT CTCAE_v5 ctcae5:C143497 A disorder characterized by an infectious process involving the gallbladder. A disorder characterized by an infectious process involving the gallbladder. Gallbladder Infection, CTCAE Gallbladder infection 10062632 C143497 Gallbladder infection Gallbladder infection A disorder characterized by an infectious process involving the gallbladder. NCI A disorder characterized by an infectious process involving the gallbladder. CTCAE_v5 Gallbladder Infection, CTCAE PT NCI Gallbladder infection PT CTCAE_v5 ctcae5:C143498 A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). Gastric Anastomotic Leak, CTCAE Gastric anastomotic leak 10065893 C143498 Gastric anastomotic leak Gastric anastomotic leak A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a gastric anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Gastric Anastomotic Leak, CTCAE PT NCI Gastric anastomotic leak PT CTCAE_v5 ctcae5:C143499 A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. Gastric Fistula, CTCAE Gastric fistula 10065713 C143499 Gastric fistula Gastric fistula A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site. CTCAE_v5 Gastric Fistula, CTCAE PT NCI Gastric fistula PT CTCAE_v5 ctcae5:C143500 A disorder characterized by bleeding from the gastric wall. A disorder characterized by bleeding from the gastric wall. Gastric Hemorrhage, CTCAE Gastric hemorrhage 10017789 C143500 Gastric hemorrhage Gastric hemorrhage A disorder characterized by bleeding from the gastric wall. NCI A disorder characterized by bleeding from the gastric wall. CTCAE_v5 Gastric Hemorrhage, CTCAE PT NCI Gastric hemorrhage PT CTCAE_v5 ctcae5:C143501 A disorder characterized by a necrotic process occurring in the gastric wall. A disorder characterized by a necrotic process occurring in the gastric wall. Gastric Necrosis, CTCAE Gastric necrosis 10051886 C143501 Gastric necrosis Gastric necrosis A disorder characterized by a necrotic process occurring in the gastric wall. NCI A disorder characterized by a necrotic process occurring in the gastric wall. CTCAE_v5 Gastric Necrosis, CTCAE PT NCI Gastric necrosis PT CTCAE_v5 ctcae5:C143502 A disorder characterized by a rupture in the stomach wall. A disorder characterized by a rupture in the stomach wall. Gastric Perforation, CTCAE Gastric perforation 10017815 C143502 Gastric perforation Gastric perforation A disorder characterized by a rupture in the stomach wall. NCI A disorder characterized by a rupture in the stomach wall. CTCAE_v5 Gastric Perforation, CTCAE PT NCI Gastric perforation PT CTCAE_v5 ctcae5:C143503 A disorder characterized by a narrowing of the lumen of the stomach. A disorder characterized by a narrowing of the lumen of the stomach. Gastric Stenosis, CTCAE Gastric stenosis 10061970 C143503 Gastric stenosis Gastric stenosis A disorder characterized by a narrowing of the lumen of the stomach. NCI A disorder characterized by a narrowing of the lumen of the stomach. CTCAE_v5 Gastric Stenosis, CTCAE PT NCI Gastric stenosis PT CTCAE_v5 ctcae5:C143504 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the stomach. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the stomach. Gastric Ulcer, CTCAE Gastric ulcer 10017822 C143504 Gastric ulcer Gastric ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the stomach. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the stomach. CTCAE_v5 Gastric Ulcer, CTCAE PT NCI Gastric ulcer PT CTCAE_v5 ctcae5:C143506 A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. Gastroesophageal Reflux Disease, CTCAE Gastroesophageal reflux disease 10066874 C143506 Gastroesophageal reflux disease Gastroesophageal reflux disease A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. NCI A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion. CTCAE_v5 Gastroesophageal Reflux Disease, CTCAE PT NCI Gastroesophageal reflux disease PT CTCAE_v5 ctcae5:C143507 A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). Gastrointestinal Anastomotic Leak, CTCAE Gastrointestinal anastomotic leak 10065879 C143507 Gastrointestinal anastomotic leak Gastrointestinal anastomotic leak A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a gastrointestinal anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C143508 Gastrointestinal Disorders - Other, Specify, CTCAE Gastrointestinal disorders - Other, specify 10017947 C143508 Gastrointestinal disorders - Other, specify Gastrointestinal disorders - Other, specify Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C143510 A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. Gastrointestinal Pain, CTCAE Gastrointestinal pain 10017999 C143510 Gastrointestinal pain Gastrointestinal pain A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. NCI A disorder characterized by a sensation of marked discomfort in the gastrointestinal region. CTCAE_v5 Gastrointestinal Pain, CTCAE PT NCI Gastrointestinal pain PT CTCAE_v5 ctcae5:C143511 A disorder characterized by a necrotic process occurring in the gastrointestinal tract stoma. A disorder characterized by a necrotic process occurring in the gastrointestinal tract stoma. Gastrointestinal Stoma Necrosis, CTCAE Gastrointestinal stoma necrosis 10065712 C143511 Gastrointestinal stoma necrosis Gastrointestinal stoma necrosis A disorder characterized by a necrotic process occurring in the gastrointestinal tract stoma. NCI A disorder characterized by a necrotic process occurring in the gastrointestinal tract stoma. CTCAE_v5 Gastrointestinal Stoma Necrosis, CTCAE PT NCI Gastrointestinal stoma necrosis PT CTCAE_v5 ctcae5:C143512 A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. Gastroparesis Gastroparesis, CTCAE 10018043 C143512 Gastroparesis Gastroparesis A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. NCI A disorder characterized by an incomplete paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine. CTCAE_v5 Gastroparesis PT CTCAE_v5 Gastroparesis, CTCAE PT NCI ctcae5:C143513 General Disorders and Administration Site Conditions - Other, Specify, CTCAE General disorders and administration site conditions - Other, specify 10018065 C143513 General disorders and administration site conditions - Other, specify General disorders and administration site conditions - Other, specify General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C143514 A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. Generalized Muscle Weakness, CTCAE Generalized muscle weakness 10062572 C143514 Generalized muscle weakness Generalized muscle weakness A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. NCI A disorder characterized by a reduction in the strength of muscles in multiple anatomic sites. CTCAE_v5 Generalized Muscle Weakness, CTCAE PT NCI Generalized muscle weakness PT CTCAE_v5 ctcae5:C143515 A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. Genital Edema, CTCAE Genital edema 10018146 C143515 Genital edema Genital edema A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. NCI A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals. CTCAE_v5 Genital Edema, CTCAE PT NCI Genital edema PT CTCAE_v5 ctcae5:C143516 A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. GGT Increased, CTCAE GGT increased 10056910 C143516 GGT increased GGT increased A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. NCI A finding based on laboratory test results that indicate higher than normal levels of the enzyme gamma-glutamyltransferase in the blood specimen. GGT (gamma-glutamyltransferase ) catalyzes the transfer of a gamma glutamyl group from a gamma glutamyl peptide to another peptide, amino acids or water. CTCAE_v5 GGT Increased, CTCAE PT NCI GGT increased PT CTCAE_v5 ctcae5:C143518 A disorder characterized by dysfunction of the glossopharyngeal nerve (ninth cranial nerve). A disorder characterized by dysfunction of the glossopharyngeal nerve (ninth cranial nerve). Glossopharyngeal Nerve Disorder, CTCAE Glossopharyngeal nerve disorder 10061185 C143518 Glossopharyngeal nerve disorder Glossopharyngeal nerve disorder A disorder characterized by dysfunction of the glossopharyngeal nerve (ninth cranial nerve). NCI A disorder characterized by dysfunction of the glossopharyngeal nerve (ninth cranial nerve). CTCAE_v5 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C143519 A disorder characterized by an inability to properly metabolize glucose. A disorder characterized by an inability to properly metabolize glucose. Glucose Intolerance, CTCAE Glucose intolerance 10052426 C143519 Glucose intolerance Glucose intolerance A disorder characterized by an inability to properly metabolize glucose. NCI A disorder characterized by an inability to properly metabolize glucose. CTCAE_v5 Glucose Intolerance, CTCAE PT NCI Glucose intolerance PT CTCAE_v5 ctcae5:C143520 A disorder characterized by greater growth than expected for age. A disorder characterized by greater growth than expected for age. Growth Accelerated, CTCAE Growth accelerated 10018746 C143520 Growth accelerated Growth accelerated A disorder characterized by greater growth than expected for age. NCI A disorder characterized by greater growth than expected for age. CTCAE_v5 Growth Accelerated, CTCAE PT NCI Growth accelerated PT CTCAE_v5 ctcae5:C143521 A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. Growth Hormone Abnormal, CTCAE Growth hormone abnormal 10018748 C143521 Growth hormone abnormal Growth hormone abnormal A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. NCI A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological specimen. CTCAE_v5 Growth Hormone Abnormal, CTCAE PT NCI Growth hormone abnormal PT CTCAE_v5 ctcae5:C143522 A disorder characterized by stature that is smaller than normal as expected for age. A disorder characterized by stature that is smaller than normal as expected for age. Growth Suppression, CTCAE Growth suppression 10018761 C143522 Growth suppression Growth suppression A disorder characterized by stature that is smaller than normal as expected for age. NCI A disorder characterized by stature that is smaller than normal as expected for age. CTCAE_v5 Growth Suppression, CTCAE PT NCI Growth suppression PT CTCAE_v5 ctcae5:C143523 A disorder characterized by an infectious process involving the gums. A disorder characterized by an infectious process involving the gums. Gum Infection, CTCAE Gum infection 10018784 C143523 Gum infection Gum infection A disorder characterized by an infectious process involving the gums. NCI A disorder characterized by an infectious process involving the gums. CTCAE_v5 Gum Infection, CTCAE PT NCI Gum infection PT CTCAE_v5 ctcae5:C143525 A disorder characterized by a false sensory perception in the absence of an external stimulus. A disorder characterized by a false sensory perception in the absence of an external stimulus. Hallucinations Hallucinations, CTCAE 10019077 C143525 Hallucinations Hallucinations A disorder characterized by a false sensory perception in the absence of an external stimulus. NCI A disorder characterized by a false sensory perception in the absence of an external stimulus. CTCAE_v5 Hallucinations PT CTCAE_v5 Hallucinations, CTCAE PT NCI ctcae5:C143526 A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. Haptoglobin Decreased, CTCAE Haptoglobin decreased 10019150 C143526 Haptoglobin decreased Haptoglobin decreased A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. NCI A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen. CTCAE_v5 Haptoglobin Decreased, CTCAE PT NCI Haptoglobin decreased PT CTCAE_v5 ctcae5:C143527 A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. Headache Headache, CTCAE 10019211 C143527 Headache Headache A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. NCI A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve. CTCAE_v5 Headache PT CTCAE_v5 Headache, CTCAE PT NCI ctcae5:C143528 A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. Hearing Impaired, CTCAE Hearing impaired 10019245 C143528 Hearing impaired Hearing impaired A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. NCI A disorder characterized by partial or complete loss of the ability to detect or understand sounds resulting from damage to ear structures. CTCAE_v5 Hearing Impaired, CTCAE PT NCI Hearing impaired PT CTCAE_v5 ctcae5:C143529 A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. Heart Failure, CTCAE Heart failure 10019279 C143529 Heart failure Heart failure A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. NCI A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure. CTCAE_v5 Heart Failure, CTCAE PT NCI Heart failure PT CTCAE_v5 ctcae5:C143531 A disorder characterized by the presence of blood in a fallopian tube. A disorder characterized by the presence of blood in a fallopian tube. Hematosalpinx Hematosalpinx, CTCAE 10060602 C143531 Hematosalpinx Hematosalpinx A disorder characterized by the presence of blood in a fallopian tube. NCI A disorder characterized by the presence of blood in a fallopian tube. CTCAE_v5 Hematosalpinx PT CTCAE_v5 Hematosalpinx, CTCAE PT NCI ctcae5:C143532 A disorder characterized by laboratory test results that indicate blood in the urine. A disorder characterized by laboratory test results that indicate blood in the urine. Hematuria Hematuria, CTCAE 10019450 C143532 Hematuria Hematuria A disorder characterized by laboratory test results that indicate blood in the urine. NCI A disorder characterized by laboratory test results that indicate blood in the urine. CTCAE_v5 Hematuria PT CTCAE_v5 Hematuria, CTCAE PT NCI ctcae5:C143533 A finding based on laboratory test results that indicate increased levels of hemoglobin above normal. A finding based on laboratory test results that indicate increased levels of hemoglobin above normal. Hemoglobin Increased, CTCAE Hemoglobin increased 10055599 C143533 Hemoglobin increased Hemoglobin increased A finding based on laboratory test results that indicate increased levels of hemoglobin above normal. NCI A finding based on laboratory test results that indicate increased levels of hemoglobin above normal. CTCAE_v5 Hemoglobin Increased, CTCAE PT NCI Hemoglobin increased PT CTCAE_v5 ctcae5:C143536 A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. Hemolytic Uremic Syndrome, CTCAE Hemolytic uremic syndrome 10019515 C143536 Hemolytic uremic syndrome Hemolytic uremic syndrome A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. NCI A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia. CTCAE_v5 Hemolytic Uremic Syndrome, CTCAE PT NCI Hemolytic uremic syndrome PT CTCAE_v5 ctcae5:C143537 A disorder characterized by bleeding from the hemorrhoids. A disorder characterized by bleeding from the hemorrhoids. Hemorrhoidal Hemorrhage, CTCAE Hemorrhoidal hemorrhage 10060640 C143537 Hemorrhoidal hemorrhage Hemorrhoidal hemorrhage A disorder characterized by bleeding from the hemorrhoids. NCI A disorder characterized by bleeding from the hemorrhoids. CTCAE_v5 Hemorrhoidal Hemorrhage, CTCAE PT NCI Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C143539 A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law. A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law. Hepatic Failure, CTCAE Hepatic failure 10019663 C143539 Hepatic failure Hepatic failure A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law. NCI A disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liever injury (DILI) as defined by Hy's Law. CTCAE_v5 Hepatic Failure, CTCAE PT NCI Hepatic failure PT CTCAE_v5 ctcae5:C143540 A disorder characterized by bleeding from the liver. A disorder characterized by bleeding from the liver. Hepatic Hemorrhage, CTCAE Hepatic hemorrhage 10019678 C143540 Hepatic hemorrhage Hepatic hemorrhage A disorder characterized by bleeding from the liver. NCI A disorder characterized by bleeding from the liver. CTCAE_v5 Hepatic Hemorrhage, CTCAE PT NCI Hepatic hemorrhage PT CTCAE_v5 ctcae5:C143541 A disorder characterized by an infectious process involving the liver. A disorder characterized by an infectious process involving the liver. Hepatic Infection, CTCAE Hepatic infection 10056522 C143541 Hepatic infection Hepatic infection A disorder characterized by an infectious process involving the liver. NCI A disorder characterized by an infectious process involving the liver. CTCAE_v5 Hepatic Infection, CTCAE PT NCI Hepatic infection PT CTCAE_v5 ctcae5:C143542 A disorder characterized by a sensation of marked discomfort in the liver region. A disorder characterized by a sensation of marked discomfort in the liver region. Hepatic Pain, CTCAE Hepatic pain 10019705 C143542 Hepatic pain Hepatic pain A disorder characterized by a sensation of marked discomfort in the liver region. NCI A disorder characterized by a sensation of marked discomfort in the liver region. CTCAE_v5 Hepatic Pain, CTCAE PT NCI Hepatic pain PT CTCAE_v5 ctcae5:C143543 A disorder characterized by a viral pathologic process involving the liver parenchyma. A disorder characterized by a viral pathologic process involving the liver parenchyma. Hepatitis Viral, CTCAE Hepatitis viral 10019799 C143543 Hepatitis viral Hepatitis viral A disorder characterized by a viral pathologic process involving the liver parenchyma. NCI A disorder characterized by a viral pathologic process involving the liver parenchyma. CTCAE_v5 Hepatitis Viral, CTCAE PT NCI Hepatitis viral PT CTCAE_v5 ctcae5:C143544 Hepatobiliary Disorders - Other, Specify, CTCAE Hepatobiliary disorders - Other, specify 10019805 C143544 Hepatobiliary disorders - Other, specify Hepatobiliary disorders - Other, specify Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C143545 A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. Hiccups Hiccups, CTCAE 10020039 C143545 Hiccups Hiccups A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. NCI A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. CTCAE_v5 Hiccups PT CTCAE_v5 Hiccups, CTCAE PT NCI ctcae5:C143546 A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. Hip Fracture, CTCAE Hip fracture 10020100 C143546 Hip fracture Hip fracture A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. NCI A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. CTCAE_v5 Hip Fracture, CTCAE PT NCI Hip fracture PT CTCAE_v5 ctcae5:C143547 A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen). A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen). Hirsutism Hirsutism, CTCAE 10020112 C143547 Hirsutism Hirsutism A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen). NCI A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, abdomen). CTCAE_v5 Hirsutism PT CTCAE_v5 Hirsutism, CTCAE PT NCI ctcae5:C143548 A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. Hoarseness Hoarseness, CTCAE 10020201 C143548 Hoarseness Hoarseness A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. NCI A disorder characterized by harsh and raspy voice arising from or spreading to the larynx. CTCAE_v5 Hoarseness PT CTCAE_v5 Hoarseness, CTCAE PT NCI ctcae5:C143549 A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. Hot Flashes, CTCAE Hot flashes 10020407 C143549 Hot flashes Hot flashes A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. NCI A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling. CTCAE_v5 Hot Flashes, CTCAE PT NCI Hot flashes PT CTCAE_v5 ctcae5:C143551 A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood. Hypercalcemia Hypercalcemia, CTCAE 10020587 C143551 Hypercalcemia Hypercalcemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (corrected for albumin) in blood. CTCAE_v5 Hypercalcemia PT CTCAE_v5 Hypercalcemia, CTCAE PT NCI ctcae5:C143552 A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. Hyperglycemia Hyperglycemia, CTCAE 10020639 C143552 Hyperglycemia Hyperglycemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of blood sugar. It is usually an indication of diabetes mellitus or glucose intolerance. CTCAE_v5 Hyperglycemia PT CTCAE_v5 Hyperglycemia, CTCAE PT NCI ctcae5:C143553 A disorder characterized by excessive sweating. A disorder characterized by excessive sweating. Hyperhidrosis Hyperhidrosis, CTCAE 10020642 C143553 Hyperhidrosis Hyperhidrosis A disorder characterized by excessive sweating. NCI A disorder characterized by excessive sweating. CTCAE_v5 Hyperhidrosis PT CTCAE_v5 Hyperhidrosis, CTCAE PT NCI ctcae5:C143554 A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. Hyperkalemia Hyperkalemia, CTCAE 10020647 C143554 Hyperkalemia Hyperkalemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs. CTCAE_v5 Hyperkalemia PT CTCAE_v5 Hyperkalemia, CTCAE PT NCI ctcae5:C143555 A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. Hypermagnesemia Hypermagnesemia, CTCAE 10020670 C143555 Hypermagnesemia Hypermagnesemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood. CTCAE_v5 Hypermagnesemia PT CTCAE_v5 Hypermagnesemia, CTCAE PT NCI ctcae5:C143556 A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. Hypernatremia Hypernatremia, CTCAE 10020680 C143556 Hypernatremia Hypernatremia A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of sodium in the blood. CTCAE_v5 Hypernatremia PT CTCAE_v5 Hypernatremia, CTCAE PT NCI ctcae5:C143557 A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). Hyperparathyroidism Hyperparathyroidism, CTCAE 10020705 C143557 Hyperparathyroidism Hyperparathyroidism A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). NCI A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood). CTCAE_v5 Hyperparathyroidism PT CTCAE_v5 Hyperparathyroidism, CTCAE PT NCI ctcae5:C143558 A disorder characterized by characterized by excessive sleepiness during the daytime. A disorder characterized by characterized by excessive sleepiness during the daytime. Hypersomnia Hypersomnia, CTCAE 10020765 C143558 Hypersomnia Hypersomnia A disorder characterized by characterized by excessive sleepiness during the daytime. NCI A disorder characterized by characterized by excessive sleepiness during the daytime. CTCAE_v5 Hypersomnia PT CTCAE_v5 Hypersomnia, CTCAE PT NCI ctcae5:C143560 A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. Hyperthyroidism Hyperthyroidism, CTCAE 10020850 C143560 Hyperthyroidism Hyperthyroidism A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. NCI A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose. CTCAE_v5 Hyperthyroidism PT CTCAE_v5 Hyperthyroidism, CTCAE PT NCI ctcae5:C143561 A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. Hypertrichosis Hypertrichosis, CTCAE 10020864 C143561 Hypertrichosis Hypertrichosis A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. NCI A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race. CTCAE_v5 Hypertrichosis PT CTCAE_v5 Hypertrichosis, CTCAE PT NCI ctcae5:C143562 A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. Hypertriglyceridemia Hypertriglyceridemia, CTCAE 10020870 C143562 Hypertriglyceridemia Hypertriglyceridemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride concentration in the blood. CTCAE_v5 Hypertriglyceridemia PT CTCAE_v5 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C143563 A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. Hyperuricemia Hyperuricemia, CTCAE 10020907 C143563 Hyperuricemia Hyperuricemia A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. NCI A disorder characterized by laboratory test results that indicate an elevation in the concentration of uric acid. CTCAE_v5 Hyperuricemia PT CTCAE_v5 Hyperuricemia, CTCAE PT NCI ctcae5:C143564 A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. Hypoalbuminemia Hypoalbuminemia, CTCAE 10020943 C143564 Hypoalbuminemia Hypoalbuminemia A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood. CTCAE_v5 Hypoalbuminemia PT CTCAE_v5 Hypoalbuminemia, CTCAE PT NCI ctcae5:C143565 A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood. A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood. Hypocalcemia Hypocalcemia, CTCAE 10020949 C143565 Hypocalcemia Hypocalcemia A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for albumin) in the blood. CTCAE_v5 Hypocalcemia PT CTCAE_v5 Hypocalcemia, CTCAE PT NCI ctcae5:C143566 A disorder characterized by dysfunction of the hypoglossal nerve (twelfth cranial nerve). A disorder characterized by dysfunction of the hypoglossal nerve (twelfth cranial nerve). Hypoglossal Nerve Disorder, CTCAE Hypoglossal nerve disorder 10061212 C143566 Hypoglossal nerve disorder Hypoglossal nerve disorder A disorder characterized by dysfunction of the hypoglossal nerve (twelfth cranial nerve). NCI A disorder characterized by dysfunction of the hypoglossal nerve (twelfth cranial nerve). CTCAE_v5 Hypoglossal Nerve Disorder, CTCAE PT NCI Hypoglossal nerve disorder PT CTCAE_v5 ctcae5:C143567 A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. Hypoglycemia Hypoglycemia, CTCAE 10021005 C143567 Hypoglycemia Hypoglycemia A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood. CTCAE_v5 Hypoglycemia PT CTCAE_v5 Hypoglycemia, CTCAE PT NCI ctcae5:C143568 A disorder characterized by reduced sweating. A disorder characterized by reduced sweating. Hypohidrosis Hypohidrosis, CTCAE 10021013 C143568 Hypohidrosis Hypohidrosis A disorder characterized by reduced sweating. NCI A disorder characterized by reduced sweating. CTCAE_v5 Hypohidrosis PT CTCAE_v5 Hypohidrosis, CTCAE PT NCI ctcae5:C143569 A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. Hypokalemia Hypokalemia, CTCAE 10021018 C143569 Hypokalemia Hypokalemia A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of potassium in the blood. CTCAE_v5 Hypokalemia PT CTCAE_v5 Hypokalemia, CTCAE PT NCI ctcae5:C143570 A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. Hypomagnesemia Hypomagnesemia, CTCAE 10021028 C143570 Hypomagnesemia Hypomagnesemia A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood. CTCAE_v5 Hypomagnesemia PT CTCAE_v5 Hypomagnesemia, CTCAE PT NCI ctcae5:C143571 A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. Hyponatremia Hyponatremia, CTCAE 10021038 C143571 Hyponatremia Hyponatremia A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of sodium in the blood. CTCAE_v5 Hyponatremia PT CTCAE_v5 Hyponatremia, CTCAE PT NCI ctcae5:C143572 A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. Hypoparathyroidism Hypoparathyroidism, CTCAE 10021041 C143572 Hypoparathyroidism Hypoparathyroidism A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. NCI A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands. CTCAE_v5 Hypoparathyroidism PT CTCAE_v5 Hypoparathyroidism, CTCAE PT NCI ctcae5:C143573 A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. Hypophosphatemia Hypophosphatemia, CTCAE 10021059 C143573 Hypophosphatemia Hypophosphatemia A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. NCI A disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood. CTCAE_v5 Hypophosphatemia PT CTCAE_v5 Hypophosphatemia, CTCAE PT NCI ctcae5:C143576 A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. Hypothyroidism Hypothyroidism, CTCAE 10021114 C143576 Hypothyroidism Hypothyroidism A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. NCI A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland. CTCAE_v5 Hypothyroidism PT CTCAE_v5 Hypothyroidism, CTCAE PT NCI ctcae5:C143578 A disorder characterized by a narrowing of the lumen of the ileum. A disorder characterized by a narrowing of the lumen of the ileum. Ileal Stenosis, CTCAE Ileal stenosis 10021307 C143578 Ileal stenosis Ileal stenosis A disorder characterized by a narrowing of the lumen of the ileum. NCI A disorder characterized by a narrowing of the lumen of the ileum. CTCAE_v5 Ileal Stenosis, CTCAE PT NCI Ileal stenosis PT CTCAE_v5 ctcae5:C143580 Immune System Disorders - Other, Specify, CTCAE Immune system disorders - Other, specify 10021428 C143580 Immune system disorders - Other, specify Immune system disorders - Other, specify Immune System Disorders - Other, Specify, CTCAE PT NCI Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C143581 Infections and Infestations - Other, Specify, CTCAE Infections and infestations - Other, specify 10021881 C143581 Infections and infestations - Other, specify Infections and infestations - Other, specify Infections and Infestations - Other, Specify, CTCAE PT NCI Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C143582 A disorder characterized by an infectious process involving the skeletal muscles. A disorder characterized by an infectious process involving the skeletal muscles. Infective Myositis, CTCAE Infective myositis 10021918 C143582 Infective myositis Infective myositis A disorder characterized by an infectious process involving the skeletal muscles. NCI A disorder characterized by an infectious process involving the skeletal muscles. CTCAE_v5 Infective Myositis, CTCAE PT NCI Infective myositis PT CTCAE_v5 ctcae5:C143583 A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. Infusion Related Reaction, CTCAE Infusion related reaction 10051792 C143583 Infusion related reaction Infusion related reaction A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. NCI A disorder characterized by adverse reaction to the infusion of pharmacological or biological substances. CTCAE_v5 Infusion Related Reaction, CTCAE PT NCI Infusion related reaction PT CTCAE_v5 ctcae5:C143584 A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. Infusion Site Extravasation, CTCAE Infusion site extravasation 10064774 C143584 Infusion site extravasation Infusion site extravasation A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. NCI A disorder characterized by leakage of the infusion into the surrounding tissue. Signs and symptoms may include induration, erythema, swelling, burning sensation and marked discomfort at the infusion site. CTCAE_v5 Infusion Site Extravasation, CTCAE PT NCI Infusion site extravasation PT CTCAE_v5 ctcae5:C143585 A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. Injection Site Reaction, CTCAE Injection site reaction 10022095 C143585 Injection site reaction Injection site reaction A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. NCI A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injection. CTCAE_v5 Injection Site Reaction, CTCAE PT NCI Injection site reaction PT CTCAE_v5 ctcae5:C143586 A finding of damage to the carotid artery. A finding of damage to the carotid artery. Injury To Carotid Artery, CTCAE Injury to carotid artery 10022161 C143586 Injury to carotid artery Injury to carotid artery A finding of damage to the carotid artery. NCI A finding of damage to the carotid artery. CTCAE_v5 Injury To Carotid Artery, CTCAE PT NCI Injury to carotid artery PT CTCAE_v5 ctcae5:C143587 A finding of damage to the jugular vein. A finding of damage to the jugular vein. Injury To Jugular Vein, CTCAE Injury to jugular vein 10065849 C143587 Injury to jugular vein Injury to jugular vein A finding of damage to the jugular vein. NCI A finding of damage to the jugular vein. CTCAE_v5 Injury To Jugular Vein, CTCAE PT NCI Injury to jugular vein PT CTCAE_v5 ctcae5:C143588 A finding of damage to the superior vena cava. A finding of damage to the superior vena cava. Injury To Superior Vena Cava, CTCAE Injury to superior vena cava 10022356 C143588 Injury to superior vena cava Injury to superior vena cava A finding of damage to the superior vena cava. NCI A finding of damage to the superior vena cava. CTCAE_v5 Injury To Superior Vena Cava, CTCAE PT NCI Injury to superior vena cava PT CTCAE_v5 ctcae5:C143589 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Injury, poisoning and procedural complications - Other, specify 10022117 C143589 Injury, poisoning and procedural complications - Other, specify Injury, poisoning and procedural complications - Other, specify Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C143590 A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. INR Increased, CTCAE INR increased 10022402 C143590 INR increased INR increased A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. NCI A finding based on laboratory test results that indicate an increase in the ratio of the patient's prothrombin time to a control sample in the blood. CTCAE_v5 INR Increased, CTCAE PT NCI INR increased PT CTCAE_v5 ctcae5:C143592 A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). Intestinal Stoma Leak, CTCAE Intestinal stoma leak 10059095 C143592 Intestinal stoma leak Intestinal stoma leak A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). NCI A finding of leakage of contents from an intestinal stoma (surgically created opening on the surface of the body). CTCAE_v5 Intestinal Stoma Leak, CTCAE PT NCI Intestinal stoma leak PT CTCAE_v5 ctcae5:C143593 A disorder characterized by blockage of the normal flow of the contents of the intestinal stoma. A disorder characterized by blockage of the normal flow of the contents of the intestinal stoma. Intestinal Stoma Obstruction, CTCAE Intestinal stoma obstruction 10059094 C143593 Intestinal stoma obstruction Intestinal stoma obstruction A disorder characterized by blockage of the normal flow of the contents of the intestinal stoma. NCI A disorder characterized by blockage of the normal flow of the contents of the intestinal stoma. CTCAE_v5 Intestinal Stoma Obstruction, CTCAE PT NCI Intestinal stoma obstruction PT CTCAE_v5 ctcae5:C143594 A disorder characterized by bleeding from the intestinal stoma. A disorder characterized by bleeding from the intestinal stoma. Intestinal Stoma Site Bleeding, CTCAE Intestinal stoma site bleeding 10049468 C143594 Intestinal stoma site bleeding Intestinal stoma site bleeding A disorder characterized by bleeding from the intestinal stoma. NCI A disorder characterized by bleeding from the intestinal stoma. CTCAE_v5 Intestinal Stoma Site Bleeding, CTCAE PT NCI Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C143595 A disorder characterized by bleeding in the abdominal cavity. A disorder characterized by bleeding in the abdominal cavity. Intra-Abdominal Hemorrhage, CTCAE Intra-abdominal hemorrhage 10055291 C143595 Intra-abdominal hemorrhage Intra-abdominal hemorrhage A disorder characterized by bleeding in the abdominal cavity. NCI A disorder characterized by bleeding in the abdominal cavity. CTCAE_v5 Intra-Abdominal Hemorrhage, CTCAE PT NCI Intra-abdominal hemorrhage PT CTCAE_v5 ctcae5:C143596 A disorder characterized by bleeding from the cranium. A disorder characterized by bleeding from the cranium. Intracranial Hemorrhage, CTCAE Intracranial hemorrhage 10022763 C143596 Intracranial hemorrhage Intracranial hemorrhage A disorder characterized by bleeding from the cranium. NCI A disorder characterized by bleeding from the cranium. CTCAE_v5 Intracranial Hemorrhage, CTCAE PT NCI Intracranial hemorrhage PT CTCAE_v5 ctcae5:C143597 A finding of damage to an artery during a surgical procedure. A finding of damage to an artery during a surgical procedure. Intraoperative Arterial Injury, CTCAE Intraoperative arterial injury 10065826 C143597 Intraoperative arterial injury Intraoperative arterial injury A finding of damage to an artery during a surgical procedure. NCI A finding of damage to an artery during a surgical procedure. CTCAE_v5 Intraoperative Arterial Injury, CTCAE PT NCI Intraoperative arterial injury PT CTCAE_v5 ctcae5:C143598 A finding of damage to the breast parenchyma during a surgical procedure. A finding of damage to the breast parenchyma during a surgical procedure. Intraoperative Breast Injury, CTCAE Intraoperative breast injury 10065831 C143598 Intraoperative breast injury Intraoperative breast injury A finding of damage to the breast parenchyma during a surgical procedure. NCI A finding of damage to the breast parenchyma during a surgical procedure. CTCAE_v5 Intraoperative Breast Injury, CTCAE PT NCI Intraoperative breast injury PT CTCAE_v5 ctcae5:C143599 A finding of damage to the heart during a surgical procedure. A finding of damage to the heart during a surgical procedure. Intraoperative Cardiac Injury, CTCAE Intraoperative cardiac injury 10065843 C143599 Intraoperative cardiac injury Intraoperative cardiac injury A finding of damage to the heart during a surgical procedure. NCI A finding of damage to the heart during a surgical procedure. CTCAE_v5 Intraoperative Cardiac Injury, CTCAE PT NCI Intraoperative cardiac injury PT CTCAE_v5 ctcae5:C143600 A finding of damage to the ear during a surgical procedure. A finding of damage to the ear during a surgical procedure. Intraoperative Ear Injury, CTCAE Intraoperative ear injury 10065844 C143600 Intraoperative ear injury Intraoperative ear injury A finding of damage to the ear during a surgical procedure. NCI A finding of damage to the ear during a surgical procedure. CTCAE_v5 Intraoperative Ear Injury, CTCAE PT NCI Intraoperative ear injury PT CTCAE_v5 ctcae5:C143601 A finding of damage to the endocrine gland during a surgical procedure. A finding of damage to the endocrine gland during a surgical procedure. Intraoperative Endocrine Injury, CTCAE Intraoperative endocrine injury 10065834 C143601 Intraoperative endocrine injury Intraoperative endocrine injury A finding of damage to the endocrine gland during a surgical procedure. NCI A finding of damage to the endocrine gland during a surgical procedure. CTCAE_v5 Intraoperative Endocrine Injury, CTCAE PT NCI Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C143602 A finding of damage to the gastrointestinal system during a surgical procedure. A finding of damage to the gastrointestinal system during a surgical procedure. Intraoperative Gastrointestinal Injury, CTCAE Intraoperative gastrointestinal injury 10065825 C143602 Intraoperative gastrointestinal injury Intraoperative gastrointestinal injury A finding of damage to the gastrointestinal system during a surgical procedure. NCI A finding of damage to the gastrointestinal system during a surgical procedure. CTCAE_v5 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C143603 A finding of damage to the head and neck during a surgical procedure. A finding of damage to the head and neck during a surgical procedure. Intraoperative Head and Neck Injury, CTCAE Intraoperative head and neck injury 10065842 C143603 Intraoperative head and neck injury Intraoperative head and neck injury A finding of damage to the head and neck during a surgical procedure. NCI A finding of damage to the head and neck during a surgical procedure. CTCAE_v5 Intraoperative Head and Neck Injury, CTCAE PT NCI Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C143604 A finding of uncontrolled bleeding during a surgical procedure. A finding of uncontrolled bleeding during a surgical procedure. Intraoperative Hemorrhage, CTCAE Intraoperative hemorrhage 10055298 C143604 Intraoperative hemorrhage Intraoperative hemorrhage A finding of uncontrolled bleeding during a surgical procedure. NCI A finding of uncontrolled bleeding during a surgical procedure. CTCAE_v5 Intraoperative Hemorrhage, CTCAE PT NCI Intraoperative hemorrhage PT CTCAE_v5 ctcae5:C143605 A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. Intraoperative Hepatobiliary Injury, CTCAE Intraoperative hepatobiliary injury 10065827 C143605 Intraoperative hepatobiliary injury Intraoperative hepatobiliary injury A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. NCI A finding of damage to the hepatic parenchyma and/or biliary tract during a surgical procedure. CTCAE_v5 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C143606 A finding of damage to the musculoskeletal system during a surgical procedure. A finding of damage to the musculoskeletal system during a surgical procedure. Intraoperative Musculoskeletal Injury, CTCAE Intraoperative musculoskeletal injury 10065829 C143606 Intraoperative musculoskeletal injury Intraoperative musculoskeletal injury A finding of damage to the musculoskeletal system during a surgical procedure. NCI A finding of damage to the musculoskeletal system during a surgical procedure. CTCAE_v5 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C143607 A finding of damage to the nervous system during a surgical procedure. A finding of damage to the nervous system during a surgical procedure. Intraoperative Neurological Injury, CTCAE Intraoperative neurological injury 10065830 C143607 Intraoperative neurological injury Intraoperative neurological injury A finding of damage to the nervous system during a surgical procedure. NCI A finding of damage to the nervous system during a surgical procedure. CTCAE_v5 Intraoperative Neurological Injury, CTCAE PT NCI Intraoperative neurological injury PT CTCAE_v5 ctcae5:C143608 A finding of damage to the eye during a surgical procedure. A finding of damage to the eye during a surgical procedure. Intraoperative Ocular Injury, CTCAE Intraoperative ocular injury 10065841 C143608 Intraoperative ocular injury Intraoperative ocular injury A finding of damage to the eye during a surgical procedure. NCI A finding of damage to the eye during a surgical procedure. CTCAE_v5 Intraoperative Ocular Injury, CTCAE PT NCI Intraoperative ocular injury PT CTCAE_v5 ctcae5:C143609 A finding of damage to the kidney during a surgical procedure. A finding of damage to the kidney during a surgical procedure. Intraoperative Renal Injury, CTCAE Intraoperative renal injury 10065845 C143609 Intraoperative renal injury Intraoperative renal injury A finding of damage to the kidney during a surgical procedure. NCI A finding of damage to the kidney during a surgical procedure. CTCAE_v5 Intraoperative Renal Injury, CTCAE PT NCI Intraoperative renal injury PT CTCAE_v5 ctcae5:C143610 A finding of damage to the reproductive organs during a surgical procedure. A finding of damage to the reproductive organs during a surgical procedure. Intraoperative Reproductive Tract Injury, CTCAE Intraoperative reproductive tract injury 10065840 C143610 Intraoperative reproductive tract injury Intraoperative reproductive tract injury A finding of damage to the reproductive organs during a surgical procedure. NCI A finding of damage to the reproductive organs during a surgical procedure. CTCAE_v5 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C143611 A finding of damage to the respiratory system during a surgical procedure. A finding of damage to the respiratory system during a surgical procedure. Intraoperative Respiratory Injury, CTCAE Intraoperative respiratory injury 10065832 C143611 Intraoperative respiratory injury Intraoperative respiratory injury A finding of damage to the respiratory system during a surgical procedure. NCI A finding of damage to the respiratory system during a surgical procedure. CTCAE_v5 Intraoperative Respiratory Injury, CTCAE PT NCI Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C143612 A finding of damage to the spleen during a surgical procedure. A finding of damage to the spleen during a surgical procedure. Intraoperative Splenic Injury, CTCAE Intraoperative splenic injury 10065847 C143612 Intraoperative splenic injury Intraoperative splenic injury A finding of damage to the spleen during a surgical procedure. NCI A finding of damage to the spleen during a surgical procedure. CTCAE_v5 Intraoperative Splenic Injury, CTCAE PT NCI Intraoperative splenic injury PT CTCAE_v5 ctcae5:C143613 A finding of damage to the urinary system during a surgical procedure. A finding of damage to the urinary system during a surgical procedure. Intraoperative Urinary Injury, CTCAE Intraoperative urinary injury 10065828 C143613 Intraoperative urinary injury Intraoperative urinary injury A finding of damage to the urinary system during a surgical procedure. NCI A finding of damage to the urinary system during a surgical procedure. CTCAE_v5 Intraoperative Urinary Injury, CTCAE PT NCI Intraoperative urinary injury PT CTCAE_v5 ctcae5:C143614 A finding of damage to a vein during a surgical procedure. A finding of damage to a vein during a surgical procedure. Intraoperative Venous Injury, CTCAE Intraoperative venous injury 10065848 C143614 Intraoperative venous injury Intraoperative venous injury A finding of damage to a vein during a surgical procedure. NCI A finding of damage to a vein during a surgical procedure. CTCAE_v5 Intraoperative Venous Injury, CTCAE PT NCI Intraoperative venous injury PT CTCAE_v5 ctcae5:C143615 Investigations - Other, Specify, CTCAE Investigations - Other, specify 10022891 C143615 Investigations - Other, specify Investigations - Other, specify Investigations - Other, Specify, CTCAE PT NCI Investigations - Other, specify PT CTCAE_v5 ctcae5:C143617 A disorder characterized by a change in cycle or duration of menses from baseline. A disorder characterized by a change in cycle or duration of menses from baseline. Irregular Menstruation, CTCAE Irregular menstruation 10022992 C143617 Irregular menstruation Irregular menstruation A disorder characterized by a change in cycle or duration of menses from baseline. NCI A disorder characterized by a change in cycle or duration of menses from baseline. CTCAE_v5 Irregular Menstruation, CTCAE PT NCI Irregular menstruation PT CTCAE_v5 ctcae5:C143618 A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. Irritability Irritability, CTCAE 10022998 C143618 Irritability Irritability A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. NCI A disorder characterized by an abnormal responsiveness to stimuli or physiological arousal; may be in response to pain, fright, a drug, an emotional situation or a medical condition. CTCAE_v5 Irritability PT CTCAE_v5 Irritability, CTCAE PT NCI ctcae5:C143619 A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. Ischemia Cerebrovascular, CTCAE Ischemia cerebrovascular 10023030 C143619 Ischemia cerebrovascular Ischemia cerebrovascular A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. NCI A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. CTCAE_v5 Ischemia Cerebrovascular, CTCAE PT NCI Ischemia cerebrovascular PT CTCAE_v5 ctcae5:C143622 A disorder characterized by a rupture in the jejunal wall. A disorder characterized by a rupture in the jejunal wall. Jejunal Perforation, CTCAE Jejunal perforation 10023174 C143622 Jejunal perforation Jejunal perforation A disorder characterized by a rupture in the jejunal wall. NCI A disorder characterized by a rupture in the jejunal wall. CTCAE_v5 Jejunal Perforation, CTCAE PT NCI Jejunal perforation PT CTCAE_v5 ctcae5:C143623 A disorder characterized by a narrowing of the lumen of the jejunum. A disorder characterized by a narrowing of the lumen of the jejunum. Jejunal Stenosis, CTCAE Jejunal stenosis 10023176 C143623 Jejunal stenosis Jejunal stenosis A disorder characterized by a narrowing of the lumen of the jejunum. NCI A disorder characterized by a narrowing of the lumen of the jejunum. CTCAE_v5 Jejunal Stenosis, CTCAE PT NCI Jejunal stenosis PT CTCAE_v5 ctcae5:C143626 A disorder characterized by an infectious process involving a joint. A disorder characterized by an infectious process involving a joint. Joint Infection, CTCAE Joint infection 10023216 C143626 Joint infection Joint infection A disorder characterized by an infectious process involving a joint. NCI A disorder characterized by an infectious process involving a joint. CTCAE_v5 Joint Infection, CTCAE PT NCI Joint infection PT CTCAE_v5 ctcae5:C143627 A disorder characterized by a decrease in flexibility of a cervical spine joint. A disorder characterized by a decrease in flexibility of a cervical spine joint. Joint Range of Motion Decreased Cervical Spine, CTCAE Joint range of motion decreased cervical spine 10065796 C143627 Joint range of motion decreased cervical spine Joint range of motion decreased cervical spine A disorder characterized by a decrease in flexibility of a cervical spine joint. NCI A disorder characterized by a decrease in flexibility of a cervical spine joint. CTCAE_v5 Joint Range of Motion Decreased Cervical Spine, CTCAE PT NCI Joint range of motion decreased cervical spine PT CTCAE_v5 ctcae5:C143628 A disorder characterized by a decrease in flexibility of a lumbar spine joint. A disorder characterized by a decrease in flexibility of a lumbar spine joint. Joint Range of Motion Decreased Lumbar Spine, CTCAE Joint range of motion decreased lumbar spine 10065800 C143628 Joint range of motion decreased lumbar spine Joint range of motion decreased lumbar spine A disorder characterized by a decrease in flexibility of a lumbar spine joint. NCI A disorder characterized by a decrease in flexibility of a lumbar spine joint. CTCAE_v5 Joint Range of Motion Decreased Lumbar Spine, CTCAE PT NCI Joint range of motion decreased lumbar spine PT CTCAE_v5 ctcae5:C143629 A disorder characterized by a decrease in joint flexibility of any joint. A disorder characterized by a decrease in joint flexibility of any joint. Joint Range of Motion Decreased, CTCAE Joint range of motion decreased 10048706 C143629 Joint range of motion decreased Joint range of motion decreased A disorder characterized by a decrease in joint flexibility of any joint. NCI A disorder characterized by a decrease in joint flexibility of any joint. CTCAE_v5 Joint Range of Motion Decreased, CTCAE PT NCI Joint range of motion decreased PT CTCAE_v5 ctcae5:C143631 A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). Kidney Anastomotic Leak, CTCAE Kidney anastomotic leak 10065803 C143631 Kidney anastomotic leak Kidney anastomotic leak A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage of urine due to breakdown of a kidney anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Kidney Anastomotic Leak, CTCAE PT NCI Kidney anastomotic leak PT CTCAE_v5 ctcae5:C143632 A disorder characterized by an infectious process involving the kidney. A disorder characterized by an infectious process involving the kidney. Kidney Infection, CTCAE Kidney infection 10023424 C143632 Kidney infection Kidney infection A disorder characterized by an infectious process involving the kidney. NCI A disorder characterized by an infectious process involving the kidney. CTCAE_v5 Kidney Infection, CTCAE PT NCI Kidney infection PT CTCAE_v5 ctcae5:C143633 A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. Kyphosis Kyphosis, CTCAE 10023509 C143633 Kyphosis Kyphosis A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. NCI A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine. CTCAE_v5 Kyphosis PT CTCAE_v5 Kyphosis, CTCAE PT NCI ctcae5:C143634 A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. Lactation Disorder, CTCAE Lactation disorder 10061261 C143634 Lactation disorder Lactation disorder A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. NCI A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is observed in females and can be observed in males. CTCAE_v5 Lactation Disorder, CTCAE PT NCI Lactation disorder PT CTCAE_v5 ctcae5:C143635 A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. Large Intestinal Anastomotic Leak, CTCAE Large intestinal anastomotic leak 10065891 C143635 Large intestinal anastomotic leak Large intestinal anastomotic leak A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. NCI A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the large intestine. CTCAE_v5 Large Intestinal Anastomotic Leak, CTCAE PT NCI Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C143636 A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. Laryngeal Edema, CTCAE Laryngeal edema 10023838 C143636 Laryngeal edema Laryngeal edema A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. NCI A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx. CTCAE_v5 Laryngeal Edema, CTCAE PT NCI Laryngeal edema PT CTCAE_v5 ctcae5:C143637 A disorder characterized by an inflammation involving the larynx. A disorder characterized by an inflammation involving the larynx. Laryngeal Inflammation, CTCAE Laryngeal inflammation 10065735 C143637 Laryngeal inflammation Laryngeal inflammation A disorder characterized by an inflammation involving the larynx. NCI A disorder characterized by an inflammation involving the larynx. CTCAE_v5 Laryngeal Inflammation, CTCAE PT NCI Laryngeal inflammation PT CTCAE_v5 ctcae5:C143638 A disorder characterized by ulceration or inflammation involving the mucous membrane of the larynx. A disorder characterized by ulceration or inflammation involving the mucous membrane of the larynx. Laryngeal Mucositis, CTCAE Laryngeal mucositis 10065880 C143638 Laryngeal mucositis Laryngeal mucositis A disorder characterized by ulceration or inflammation involving the mucous membrane of the larynx. NCI A disorder characterized by ulceration or inflammation involving the mucous membrane of the larynx. CTCAE_v5 Laryngeal Mucositis, CTCAE PT NCI Laryngeal mucositis PT CTCAE_v5 ctcae5:C143639 A disorder characterized by blockage of the laryngeal airway. A disorder characterized by blockage of the laryngeal airway. Laryngeal Obstruction, CTCAE Laryngeal obstruction 10059639 C143639 Laryngeal obstruction Laryngeal obstruction A disorder characterized by blockage of the laryngeal airway. NCI A disorder characterized by blockage of the laryngeal airway. CTCAE_v5 Laryngeal Obstruction, CTCAE PT NCI Laryngeal obstruction PT CTCAE_v5 ctcae5:C143640 A disorder characterized by a narrowing of the laryngeal airway. A disorder characterized by a narrowing of the laryngeal airway. Laryngeal Stenosis, CTCAE Laryngeal stenosis 10023862 C143640 Laryngeal stenosis Laryngeal stenosis A disorder characterized by a narrowing of the laryngeal airway. NCI A disorder characterized by a narrowing of the laryngeal airway. CTCAE_v5 Laryngeal Stenosis, CTCAE PT NCI Laryngeal stenosis PT CTCAE_v5 ctcae5:C143641 A disorder characterized by an inflammatory process involving the larynx. A disorder characterized by an inflammatory process involving the larynx. Laryngitis Laryngitis, CTCAE 10023874 C143641 Laryngitis Laryngitis A disorder characterized by an inflammatory process involving the larynx. NCI A disorder characterized by an inflammatory process involving the larynx. CTCAE_v5 Laryngitis PT CTCAE_v5 Laryngitis, CTCAE PT NCI ctcae5:C143642 A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. Laryngopharyngeal Dysesthesia, CTCAE Laryngopharyngeal dysesthesia 10062667 C143642 Laryngopharyngeal dysesthesia Laryngopharyngeal dysesthesia A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. NCI A disorder characterized by an uncomfortable persistent sensation in the area of the laryngopharynx. CTCAE_v5 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C143643 A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. Laryngospasm Laryngospasm, CTCAE 10023891 C143643 Laryngospasm Laryngospasm A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. NCI A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. CTCAE_v5 Laryngospasm PT CTCAE_v5 Laryngospasm, CTCAE PT NCI ctcae5:C143645 A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. Lethargy Lethargy, CTCAE 10024264 C143645 Lethargy Lethargy A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. NCI A disorder characterized by a decrease in consciousness characterized by mental and physical inertness. CTCAE_v5 Lethargy PT CTCAE_v5 Lethargy, CTCAE PT NCI ctcae5:C143646 A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. Leukemia Secondary To Oncology Chemotherapy, CTCAE Leukemia secondary to oncology chemotherapy 10048293 C143646 Leukemia secondary to oncology chemotherapy Leukemia secondary to oncology chemotherapy A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. NCI A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents. CTCAE_v5 Leukemia Secondary To Oncology Chemotherapy, CTCAE PT NCI Leukemia secondary to oncology chemotherapy PT CTCAE_v5 ctcae5:C143647 A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. Leukocytosis Leukocytosis, CTCAE 10024378 C143647 Leukocytosis Leukocytosis A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. NCI A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the blood. CTCAE_v5 Leukocytosis PT CTCAE_v5 Leukocytosis, CTCAE PT NCI ctcae5:C143648 A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. Leukoencephalopathy Leukoencephalopathy, CTCAE 10024382 C143648 Leukoencephalopathy Leukoencephalopathy A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. NCI A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. CTCAE_v5 Leukoencephalopathy PT CTCAE_v5 Leukoencephalopathy, CTCAE PT NCI ctcae5:C143649 A disorder characterized by a decrease in sexual desire. A disorder characterized by a decrease in sexual desire. Libido Decreased, CTCAE Libido decreased 10024419 C143649 Libido decreased Libido decreased A disorder characterized by a decrease in sexual desire. NCI A disorder characterized by a decrease in sexual desire. CTCAE_v5 Libido Decreased, CTCAE PT NCI Libido decreased PT CTCAE_v5 ctcae5:C143650 A disorder characterized by an increase in sexual desire. A disorder characterized by an increase in sexual desire. Libido Increased, CTCAE Libido increased 10024421 C143650 Libido increased Libido increased A disorder characterized by an increase in sexual desire. NCI A disorder characterized by an increase in sexual desire. CTCAE_v5 Libido Increased, CTCAE PT NCI Libido increased PT CTCAE_v5 ctcae5:C143651 A disorder characterized by an infectious process involving the lips. A disorder characterized by an infectious process involving the lips. Lip Infection, CTCAE Lip infection 10065755 C143651 Lip infection Lip infection A disorder characterized by an infectious process involving the lips. NCI A disorder characterized by an infectious process involving the lips. CTCAE_v5 Lip Infection, CTCAE PT NCI Lip infection PT CTCAE_v5 ctcae5:C143652 A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. Lipase Increased, CTCAE Lipase increased 10024574 C143652 Lipase increased Lipase increased A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. NCI A finding based on laboratory test results that indicate an increase in the level of lipase in a biological specimen. CTCAE_v5 Lipase Increased, CTCAE PT NCI Lipase increased PT CTCAE_v5 ctcae5:C143653 A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. Lipohypertrophy Lipohypertrophy, CTCAE 10062315 C143653 Lipohypertrophy Lipohypertrophy A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. NCI A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. CTCAE_v5 Lipohypertrophy PT CTCAE_v5 Lipohypertrophy, CTCAE PT NCI ctcae5:C143654 A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. Localized Edema, CTCAE Localized edema 10062466 C143654 Localized edema Localized edema A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. NCI A disorder characterized by swelling due to excessive fluid accumulation at a specific anatomic site. CTCAE_v5 Localized Edema, CTCAE PT NCI Localized edema PT CTCAE_v5 ctcae5:C143655 A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. Lordosis Lordosis, CTCAE 10024842 C143655 Lordosis Lordosis A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. NCI A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine. CTCAE_v5 Lordosis PT CTCAE_v5 Lordosis, CTCAE PT NCI ctcae5:C143656 A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). Lower Gastrointestinal Hemorrhage, CTCAE Lower gastrointestinal hemorrhage 10051746 C143656 Lower gastrointestinal hemorrhage Lower gastrointestinal hemorrhage A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). NCI A disorder characterized by bleeding from the lower gastrointestinal tract (small intestine, large intestine, and anus). CTCAE_v5 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C143657 A disorder characterized by an infectious process involving the lungs, including pneumonia. A disorder characterized by an infectious process involving the lungs, including pneumonia. Lung Infection, CTCAE Lung infection 10061229 C143657 Lung infection Lung infection A disorder characterized by an infectious process involving the lungs, including pneumonia. NCI A disorder characterized by an infectious process involving the lungs, including pneumonia. CTCAE_v5 Lung Infection, CTCAE PT NCI Lung infection PT CTCAE_v5 ctcae5:C143658 A disorder characterized by an infectious process involving the lymph nodes. A disorder characterized by an infectious process involving the lymph nodes. Lymph Gland Infection, CTCAE Lymph gland infection 10050823 C143658 Lymph gland infection Lymph gland infection A disorder characterized by an infectious process involving the lymph nodes. NCI A disorder characterized by an infectious process involving the lymph nodes. CTCAE_v5 Lymph Gland Infection, CTCAE PT NCI Lymph gland infection PT CTCAE_v5 ctcae5:C143659 A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. Lymph Leakage, CTCAE Lymph leakage 10065773 C143659 Lymph leakage Lymph leakage A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. NCI A disorder characterized by the loss of lymph fluid into the surrounding tissue or body cavity. CTCAE_v5 Lymph Leakage, CTCAE PT NCI Lymph leakage PT CTCAE_v5 ctcae5:C143660 A disorder characterized by excessive fluid collection in tissues that causes swelling. A disorder characterized by excessive fluid collection in tissues that causes swelling. Lymphedema Lymphedema, CTCAE 10025233 C143660 Lymphedema Lymphedema A disorder characterized by excessive fluid collection in tissues that causes swelling. NCI A disorder characterized by excessive fluid collection in tissues that causes swelling. CTCAE_v5 Lymphedema PT CTCAE_v5 Lymphedema, CTCAE PT NCI ctcae5:C143662 A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. Lymphocyte Count Decreased, CTCAE Lymphocyte count decreased 10025256 C143662 Lymphocyte count decreased Lymphocyte count decreased A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. NCI A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specimen. CTCAE_v5 Lymphocyte Count Decreased, CTCAE PT NCI Lymphocyte count decreased PT CTCAE_v5 ctcae5:C143663 A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. Lymphocyte Count Increased, CTCAE Lymphocyte count increased 10025258 C143663 Lymphocyte count increased Lymphocyte count increased A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. NCI A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow. CTCAE_v5 Lymphocyte Count Increased, CTCAE PT NCI Lymphocyte count increased PT CTCAE_v5 ctcae5:C143665 A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. Malaise Malaise, CTCAE 10025482 C143665 Malaise Malaise A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. NCI A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. CTCAE_v5 Malaise PT CTCAE_v5 Malaise, CTCAE PT NCI ctcae5:C143666 A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. Mania Mania, CTCAE 10026749 C143666 Mania Mania A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. NCI A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. CTCAE_v5 Mania PT CTCAE_v5 Mania, CTCAE PT NCI ctcae5:C143667 A disorder characterized by an infectious process involving the mediastinum. A disorder characterized by an infectious process involving the mediastinum. Mediastinal Infection, CTCAE Mediastinal infection 10057483 C143667 Mediastinal infection Mediastinal infection A disorder characterized by an infectious process involving the mediastinum. NCI A disorder characterized by an infectious process involving the mediastinum. CTCAE_v5 Mediastinal Infection, CTCAE PT NCI Mediastinal infection PT CTCAE_v5 ctcae5:C143669 A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. Meningismus Meningismus, CTCAE 10027198 C143669 Meningismus Meningismus A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. NCI A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral meninges. CTCAE_v5 Meningismus PT CTCAE_v5 Meningismus, CTCAE PT NCI ctcae5:C143670 A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. Meningitis Meningitis, CTCAE 10027199 C143670 Meningitis Meningitis A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. NCI A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord. CTCAE_v5 Meningitis PT CTCAE_v5 Meningitis, CTCAE PT NCI ctcae5:C143671 A disorder characterized by abnormally heavy vaginal bleeding during menses. A disorder characterized by abnormally heavy vaginal bleeding during menses. Menorrhagia Menorrhagia, CTCAE 10027313 C143671 Menorrhagia Menorrhagia A disorder characterized by abnormally heavy vaginal bleeding during menses. NCI A disorder characterized by abnormally heavy vaginal bleeding during menses. CTCAE_v5 Menorrhagia PT CTCAE_v5 Menorrhagia, CTCAE PT NCI ctcae5:C143672 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Metabolism and nutrition disorders - Other, specify 10027433 C143672 Metabolism and nutrition disorders - Other, specify Metabolism and nutrition disorders - Other, specify Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C143673 A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. Middle Ear Inflammation, CTCAE Middle ear inflammation 10065838 C143673 Middle ear inflammation Middle ear inflammation A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. NCI A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middle ear. CTCAE_v5 Middle Ear Inflammation, CTCAE PT NCI Middle ear inflammation PT CTCAE_v5 ctcae5:C143674 A disorder characterized by a defect in mitral valve function or structure. A disorder characterized by a defect in mitral valve function or structure. Mitral Valve Disease, CTCAE Mitral valve disease 10061532 C143674 Mitral valve disease Mitral valve disease A disorder characterized by a defect in mitral valve function or structure. NCI A disorder characterized by a defect in mitral valve function or structure. CTCAE_v5 Mitral Valve Disease, CTCAE PT NCI Mitral valve disease PT CTCAE_v5 ctcae5:C143677 A disorder characterized by uncontrolled and purposeless movements. A disorder characterized by uncontrolled and purposeless movements. Movements Involuntary, CTCAE Movements involuntary 10028041 C143677 Movements involuntary Movements involuntary A disorder characterized by uncontrolled and purposeless movements. NCI A disorder characterized by uncontrolled and purposeless movements. CTCAE_v5 Movements Involuntary, CTCAE PT NCI Movements involuntary PT CTCAE_v5 ctcae5:C143678 A disorder characterized by an infectious process involving a mucosal surface. A disorder characterized by an infectious process involving a mucosal surface. Mucosal Infection, CTCAE Mucosal infection 10065764 C143678 Mucosal infection Mucosal infection A disorder characterized by an infectious process involving a mucosal surface. NCI A disorder characterized by an infectious process involving a mucosal surface. CTCAE_v5 Mucosal Infection, CTCAE PT NCI Mucosal infection PT CTCAE_v5 ctcae5:C143679 A disorder characterized by ulceration or inflammation of the oral mucosal. A disorder characterized by ulceration or inflammation of the oral mucosal. Mucositis Oral, CTCAE Mucositis oral 10028130 C143679 Mucositis oral Mucositis oral A disorder characterized by ulceration or inflammation of the oral mucosal. NCI A disorder characterized by ulceration or inflammation of the oral mucosal. CTCAE_v5 Mucositis Oral, CTCAE PT NCI Mucositis oral PT CTCAE_v5 ctcae5:C143680 A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. Multi-Organ Failure, CTCAE Multi-organ failure 10028154 C143680 Multi-organ failure Multi-organ failure A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. NCI A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. CTCAE_v5 Multi-Organ Failure, CTCAE PT NCI Multi-organ failure PT CTCAE_v5 ctcae5:C143681 A disorder characterized by a reduction in the strength of the muscles on the left side of the body. A disorder characterized by a reduction in the strength of the muscles on the left side of the body. Muscle Weakness Left-Sided, CTCAE Muscle weakness left-sided 10065780 C143681 Muscle weakness left-sided Muscle weakness left-sided A disorder characterized by a reduction in the strength of the muscles on the left side of the body. NCI A disorder characterized by a reduction in the strength of the muscles on the left side of the body. CTCAE_v5 Muscle Weakness Left-Sided, CTCAE PT NCI Muscle weakness left-sided PT CTCAE_v5 ctcae5:C143682 A disorder characterized by a reduction in the strength of the lower limb muscles. A disorder characterized by a reduction in the strength of the lower limb muscles. Muscle Weakness Lower Limb, CTCAE Muscle weakness lower limb 10065776 C143682 Muscle weakness lower limb Muscle weakness lower limb A disorder characterized by a reduction in the strength of the lower limb muscles. NCI A disorder characterized by a reduction in the strength of the lower limb muscles. CTCAE_v5 Muscle Weakness Lower Limb, CTCAE PT NCI Muscle weakness lower limb PT CTCAE_v5 ctcae5:C143683 A disorder characterized by a reduction in the strength of the muscles on the right side of the body. A disorder characterized by a reduction in the strength of the muscles on the right side of the body. Muscle Weakness Right-Sided, CTCAE Muscle weakness right-sided 10065794 C143683 Muscle weakness right-sided Muscle weakness right-sided A disorder characterized by a reduction in the strength of the muscles on the right side of the body. NCI A disorder characterized by a reduction in the strength of the muscles on the right side of the body. CTCAE_v5 Muscle Weakness Right-Sided, CTCAE PT NCI Muscle weakness right-sided PT CTCAE_v5 ctcae5:C143684 A disorder characterized by a reduction in the strength of the trunk muscles. A disorder characterized by a reduction in the strength of the trunk muscles. Muscle Weakness Trunk, CTCAE Muscle weakness trunk 10065795 C143684 Muscle weakness trunk Muscle weakness trunk A disorder characterized by a reduction in the strength of the trunk muscles. NCI A disorder characterized by a reduction in the strength of the trunk muscles. CTCAE_v5 Muscle Weakness Trunk, CTCAE PT NCI Muscle weakness trunk PT CTCAE_v5 ctcae5:C143685 A disorder characterized by a reduction in the strength of the upper limb muscles. A disorder characterized by a reduction in the strength of the upper limb muscles. Muscle Weakness Upper Limb, CTCAE Muscle weakness upper limb 10065895 C143685 Muscle weakness upper limb Muscle weakness upper limb A disorder characterized by a reduction in the strength of the upper limb muscles. NCI A disorder characterized by a reduction in the strength of the upper limb muscles. CTCAE_v5 Muscle Weakness Upper Limb, CTCAE PT NCI Muscle weakness upper limb PT CTCAE_v5 ctcae5:C143686 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Musculoskeletal and connective tissue disorder - Other, specify 10028395 C143686 Musculoskeletal and connective tissue disorder - Other, specify Musculoskeletal and connective tissue disorder - Other, specify Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C143687 A disorder characterized by a malformation of the musculoskeletal system. A disorder characterized by a malformation of the musculoskeletal system. Musculoskeletal Deformity, CTCAE Musculoskeletal deformity 10065783 C143687 Musculoskeletal deformity Musculoskeletal deformity A disorder characterized by a malformation of the musculoskeletal system. NCI A disorder characterized by a malformation of the musculoskeletal system. CTCAE_v5 Musculoskeletal Deformity, CTCAE PT NCI Musculoskeletal deformity PT CTCAE_v5 ctcae5:C143688 A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. Myalgia Myalgia, CTCAE 10028411 C143688 Myalgia Myalgia A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. NCI A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles. CTCAE_v5 Myalgia PT CTCAE_v5 Myalgia, CTCAE PT NCI ctcae5:C143690 A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. Myelodysplastic Syndrome, CTCAE Myelodysplastic syndrome 10028533 C143690 Myelodysplastic syndrome Myelodysplastic syndrome A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. NCI A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. CTCAE_v5 Myelodysplastic Syndrome, CTCAE PT NCI Myelodysplastic syndrome PT CTCAE_v5 ctcae5:C143691 A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. Myocardial Infarction, CTCAE Myocardial infarction 10028596 C143691 Myocardial infarction Myocardial infarction A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. NCI A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. CTCAE_v5 Myocardial Infarction, CTCAE PT NCI Myocardial infarction PT CTCAE_v5 ctcae5:C143694 A disorder characterized by a change in the color of the nail plate. A disorder characterized by a change in the color of the nail plate. Nail Discoloration, CTCAE Nail discoloration 10028691 C143694 Nail discoloration Nail discoloration A disorder characterized by a change in the color of the nail plate. NCI A disorder characterized by a change in the color of the nail plate. CTCAE_v5 Nail Discoloration, CTCAE PT NCI Nail discoloration PT CTCAE_v5 ctcae5:C143695 A disorder characterized by an infectious process involving the nail. A disorder characterized by an infectious process involving the nail. Nail Infection, CTCAE Nail infection 10061304 C143695 Nail infection Nail infection A disorder characterized by an infectious process involving the nail. NCI A disorder characterized by an infectious process involving the nail. CTCAE_v5 Nail Infection, CTCAE PT NCI Nail infection PT CTCAE_v5 ctcae5:C143696 A disorder characterized by loss of all or a portion of the nail. A disorder characterized by loss of all or a portion of the nail. Nail Loss, CTCAE Nail loss 10049281 C143696 Nail loss Nail loss A disorder characterized by loss of all or a portion of the nail. NCI A disorder characterized by loss of all or a portion of the nail. CTCAE_v5 Nail Loss, CTCAE PT NCI Nail loss PT CTCAE_v5 ctcae5:C143697 A disorder characterized by vertical or horizontal ridges on the nails. A disorder characterized by vertical or horizontal ridges on the nails. Nail Ridging, CTCAE Nail ridging 10062283 C143697 Nail ridging Nail ridging A disorder characterized by vertical or horizontal ridges on the nails. NCI A disorder characterized by vertical or horizontal ridges on the nails. CTCAE_v5 Nail Ridging, CTCAE PT NCI Nail ridging PT CTCAE_v5 ctcae5:C143698 A disorder characterized by obstruction of the nasal passage due to mucosal edema. A disorder characterized by obstruction of the nasal passage due to mucosal edema. Nasal Congestion, CTCAE Nasal congestion 10028735 C143698 Nasal congestion Nasal congestion A disorder characterized by obstruction of the nasal passage due to mucosal edema. NCI A disorder characterized by obstruction of the nasal passage due to mucosal edema. CTCAE_v5 Nasal Congestion, CTCAE PT NCI Nasal congestion PT CTCAE_v5 ctcae5:C143700 A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. Neck Edema, CTCAE Neck edema 10054482 C143700 Neck edema Neck edema A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. NCI A disorder characterized by swelling due to an accumulation of excessive fluid in the neck. CTCAE_v5 Neck Edema, CTCAE PT NCI Neck edema PT CTCAE_v5 ctcae5:C143701 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C143701 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C143702 Nervous System Disorders - Other, Specify, CTCAE Nervous system disorders - Other, specify 10029205 C143702 Nervous system disorders - Other, specify Nervous system disorders - Other, specify Nervous System Disorders - Other, Specify, CTCAE PT NCI Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C143703 A disorder characterized by intense painful sensation along a nerve or group of nerves. A disorder characterized by intense painful sensation along a nerve or group of nerves. Neuralgia Neuralgia, CTCAE 10029223 C143703 Neuralgia Neuralgia A disorder characterized by intense painful sensation along a nerve or group of nerves. NCI A disorder characterized by intense painful sensation along a nerve or group of nerves. CTCAE_v5 Neuralgia PT CTCAE_v5 Neuralgia, CTCAE PT NCI ctcae5:C143704 A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. Neutrophil Count Decreased, CTCAE Neutrophil count decreased 10029366 C143704 Neutrophil count decreased Neutrophil count decreased A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. NCI A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen. CTCAE_v5 Neutrophil Count Decreased, CTCAE PT NCI Neutrophil count decreased PT CTCAE_v5 ctcae5:C143705 A disorder characterized by an inability to see clearly in dim light. A disorder characterized by an inability to see clearly in dim light. Night Blindness, CTCAE Night blindness 10029404 C143705 Night blindness Night blindness A disorder characterized by an inability to see clearly in dim light. NCI A disorder characterized by an inability to see clearly in dim light. CTCAE_v5 Night Blindness, CTCAE PT NCI Night blindness PT CTCAE_v5 ctcae5:C143706 A disorder characterized by a malformation of the nipple. A disorder characterized by a malformation of the nipple. Nipple Deformity, CTCAE Nipple deformity 10065823 C143706 Nipple deformity Nipple deformity A disorder characterized by a malformation of the nipple. NCI A disorder characterized by a malformation of the nipple. CTCAE_v5 Nipple Deformity, CTCAE PT NCI Nipple deformity PT CTCAE_v5 ctcae5:C143707 A disorder characterized by a sensation of marked discomfort in the chest unrelated to a heart disorder. A disorder characterized by a sensation of marked discomfort in the chest unrelated to a heart disorder. Non-Cardiac Chest Pain, CTCAE Non-cardiac chest pain 10062501 C143707 Non-cardiac chest pain Non-cardiac chest pain A disorder characterized by a sensation of marked discomfort in the chest unrelated to a heart disorder. NCI A disorder characterized by a sensation of marked discomfort in the chest unrelated to a heart disorder. CTCAE_v5 Non-Cardiac Chest Pain, CTCAE PT NCI Non-cardiac chest pain PT CTCAE_v5 ctcae5:C143710 A disorder characterized by blockage of the normal flow of the contents in the stomach. A disorder characterized by blockage of the normal flow of the contents in the stomach. Obstruction Gastric, CTCAE Obstruction gastric 10029957 C143710 Obstruction gastric Obstruction gastric A disorder characterized by blockage of the normal flow of the contents in the stomach. NCI A disorder characterized by blockage of the normal flow of the contents in the stomach. CTCAE_v5 Obstruction Gastric, CTCAE PT NCI Obstruction gastric PT CTCAE_v5 ctcae5:C143711 A disorder characterized by dysfunction of the oculomotor nerve (third cranial nerve). A disorder characterized by dysfunction of the oculomotor nerve (third cranial nerve). Oculomotor Nerve Disorder, CTCAE Oculomotor nerve disorder 10053661 C143711 Oculomotor nerve disorder Oculomotor nerve disorder A disorder characterized by dysfunction of the oculomotor nerve (third cranial nerve). NCI A disorder characterized by dysfunction of the oculomotor nerve (third cranial nerve). CTCAE_v5 Oculomotor Nerve Disorder, CTCAE PT NCI Oculomotor nerve disorder PT CTCAE_v5 ctcae5:C143712 A disorder characterized by dysfunction of the olfactory nerve (first cranial nerve). A disorder characterized by dysfunction of the olfactory nerve (first cranial nerve). Olfactory Nerve Disorder, CTCAE Olfactory nerve disorder 10056388 C143712 Olfactory nerve disorder Olfactory nerve disorder A disorder characterized by dysfunction of the olfactory nerve (first cranial nerve). NCI A disorder characterized by dysfunction of the olfactory nerve (first cranial nerve). CTCAE_v5 Olfactory Nerve Disorder, CTCAE PT NCI Olfactory nerve disorder PT CTCAE_v5 ctcae5:C143713 A disorder characterized by a decrease in the number of spermatozoa in the semen. A disorder characterized by a decrease in the number of spermatozoa in the semen. Oligospermia Oligospermia, CTCAE 10030300 C143713 Oligospermia Oligospermia A disorder characterized by a decrease in the number of spermatozoa in the semen. NCI A disorder characterized by a decrease in the number of spermatozoa in the semen. CTCAE_v5 Oligospermia PT CTCAE_v5 Oligospermia, CTCAE PT NCI ctcae5:C143714 A disorder characterized by involvement of the optic nerve (second cranial nerve). A disorder characterized by involvement of the optic nerve (second cranial nerve). Optic Nerve Disorder, CTCAE Optic nerve disorder 10061322 C143714 Optic nerve disorder Optic nerve disorder A disorder characterized by involvement of the optic nerve (second cranial nerve). NCI A disorder characterized by involvement of the optic nerve (second cranial nerve). CTCAE_v5 Optic Nerve Disorder, CTCAE PT NCI Optic nerve disorder PT CTCAE_v5 ctcae5:C143715 A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. Oral Cavity Fistula, CTCAE Oral cavity fistula 10065720 C143715 Oral cavity fistula Oral cavity fistula A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the oral cavity and another organ or anatomic site. CTCAE_v5 Oral Cavity Fistula, CTCAE PT NCI Oral cavity fistula PT CTCAE_v5 ctcae5:C143716 A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. Oral Dysesthesia, CTCAE Oral dysesthesia 10054520 C143716 Oral dysesthesia Oral dysesthesia A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. NCI A disorder characterized by a burning or tingling sensation on the lips, tongue or entire mouth. CTCAE_v5 Oral Dysesthesia, CTCAE PT NCI Oral dysesthesia PT CTCAE_v5 ctcae5:C143717 A disorder characterized by a necrotic process occurring in the bone of the mandible. A disorder characterized by a necrotic process occurring in the bone of the mandible. Osteonecrosis of Jaw, CTCAE Osteonecrosis of jaw 10064658 C143717 Osteonecrosis of jaw Osteonecrosis of jaw A disorder characterized by a necrotic process occurring in the bone of the mandible. NCI A disorder characterized by a necrotic process occurring in the bone of the mandible. CTCAE_v5 Osteonecrosis of Jaw, CTCAE PT NCI Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C143719 A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. Otitis Externa, CTCAE Otitis externa 10033072 C143719 Otitis externa Otitis externa A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. NCI A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage. CTCAE_v5 Otitis Externa, CTCAE PT NCI Otitis externa PT CTCAE_v5 ctcae5:C143720 A disorder characterized by an infectious process involving the middle ear. A disorder characterized by an infectious process involving the middle ear. Otitis Media, CTCAE Otitis media 10033078 C143720 Otitis media Otitis media A disorder characterized by an infectious process involving the middle ear. NCI A disorder characterized by an infectious process involving the middle ear. CTCAE_v5 Otitis Media, CTCAE PT NCI Otitis media PT CTCAE_v5 ctcae5:C143721 A disorder characterized by an infectious process involving the ovary. A disorder characterized by an infectious process involving the ovary. Ovarian Infection, CTCAE Ovarian infection 10055005 C143721 Ovarian infection Ovarian infection A disorder characterized by an infectious process involving the ovary. NCI A disorder characterized by an infectious process involving the ovary. CTCAE_v5 Ovarian Infection, CTCAE PT NCI Ovarian infection PT CTCAE_v5 ctcae5:C143722 A disorder characterized by tearing or disruption of the ovarian tissue. A disorder characterized by tearing or disruption of the ovarian tissue. Ovarian Rupture, CTCAE Ovarian rupture 10033279 C143722 Ovarian rupture Ovarian rupture A disorder characterized by tearing or disruption of the ovarian tissue. NCI A disorder characterized by tearing or disruption of the ovarian tissue. CTCAE_v5 Ovarian Rupture, CTCAE PT NCI Ovarian rupture PT CTCAE_v5 ctcae5:C143723 A disorder characterized by a sensation of marked discomfort in the upper or lower extremities. A disorder characterized by a sensation of marked discomfort in the upper or lower extremities. Pain In Extremity, CTCAE Pain in extremity 10033425 C143723 Pain in extremity Pain in extremity A disorder characterized by a sensation of marked discomfort in the upper or lower extremities. NCI A disorder characterized by a sensation of marked discomfort in the upper or lower extremities. CTCAE_v5 Pain In Extremity, CTCAE PT NCI Pain in extremity PT CTCAE_v5 ctcae5:C143724 A disorder characterized by a sensation of marked discomfort in the skin. A disorder characterized by a sensation of marked discomfort in the skin. Pain of Skin, CTCAE Pain of skin 10033474 C143724 Pain of skin Pain of skin A disorder characterized by a sensation of marked discomfort in the skin. NCI A disorder characterized by a sensation of marked discomfort in the skin. CTCAE_v5 Pain of Skin, CTCAE PT NCI Pain of skin PT CTCAE_v5 ctcae5:C143725 A disorder characterized by the sensation of marked discomfort, distress or agony. A disorder characterized by the sensation of marked discomfort, distress or agony. Pain Pain, CTCAE 10033371 C143725 Pain Pain A disorder characterized by the sensation of marked discomfort, distress or agony. NCI A disorder characterized by the sensation of marked discomfort, distress or agony. CTCAE_v5 Pain PT CTCAE_v5 Pain, CTCAE PT NCI ctcae5:C143726 A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome. A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome. Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE Palmar-plantar erythrodysesthesia syndrome 10054524 C143726 Palmar-plantar erythrodysesthesia syndrome Palmar-plantar erythrodysesthesia syndrome A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome. NCI A disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome. CTCAE_v5 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE PT NCI Palmar-plantar erythrodysesthesia syndrome PT CTCAE_v5 ctcae5:C143728 A disorder characterized by an infectious process involving the pancreas. A disorder characterized by an infectious process involving the pancreas. Pancreas Infection, CTCAE Pancreas infection 10051741 C143728 Pancreas infection Pancreas infection A disorder characterized by an infectious process involving the pancreas. NCI A disorder characterized by an infectious process involving the pancreas. CTCAE_v5 Pancreas Infection, CTCAE PT NCI Pancreas infection PT CTCAE_v5 ctcae5:C143729 A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). Pancreatic Anastomotic Leak, CTCAE Pancreatic anastomotic leak 10050457 C143729 Pancreatic anastomotic leak Pancreatic anastomotic leak A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a pancreatic anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Pancreatic Anastomotic Leak, CTCAE PT NCI Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C143730 A disorder characterized by a narrowing of the lumen of the pancreatic duct. A disorder characterized by a narrowing of the lumen of the pancreatic duct. Pancreatic Duct Stenosis, CTCAE Pancreatic duct stenosis 10065703 C143730 Pancreatic duct stenosis Pancreatic duct stenosis A disorder characterized by a narrowing of the lumen of the pancreatic duct. NCI A disorder characterized by a narrowing of the lumen of the pancreatic duct. CTCAE_v5 Pancreatic Duct Stenosis, CTCAE PT NCI Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C143731 A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. Pancreatic Enzymes Decreased, CTCAE Pancreatic enzymes decreased 10062646 C143731 Pancreatic enzymes decreased Pancreatic enzymes decreased A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. NCI A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biological specimen. CTCAE_v5 Pancreatic Enzymes Decreased, CTCAE PT NCI Pancreatic enzymes decreased PT CTCAE_v5 ctcae5:C143732 A disorder characterized by a necrotic process occurring in the pancreas. A disorder characterized by a necrotic process occurring in the pancreas. Pancreatic Necrosis, CTCAE Pancreatic necrosis 10058096 C143732 Pancreatic necrosis Pancreatic necrosis A disorder characterized by a necrotic process occurring in the pancreas. NCI A disorder characterized by a necrotic process occurring in the pancreas. CTCAE_v5 Pancreatic Necrosis, CTCAE PT NCI Pancreatic necrosis PT CTCAE_v5 ctcae5:C143734 A disorder characterized by swelling around the optic disc. A disorder characterized by swelling around the optic disc. Papilledema Papilledema, CTCAE 10033703 C143734 Papilledema Papilledema A disorder characterized by swelling around the optic disc. NCI A disorder characterized by swelling around the optic disc. CTCAE_v5 Papilledema PT CTCAE_v5 Papilledema, CTCAE PT NCI ctcae5:C143735 A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back. Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back. Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. Papulopustular Rash, CTCAE Papulopustular rash 10069138 C143735 Papulopustular rash Papulopustular rash A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back. Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. NCI A disorder characterized by an eruption consisting of papules (a small, raised pimple) and pustules (a small pus filled blister), typically appearing in face, scalp, and upper chest and back. Unlike acne, this rash does not present with whiteheads or blackheads, and can be symptomatic, with itchy or tender lesions. CTCAE_v5 Papulopustular Rash, CTCAE PT NCI Papulopustular rash PT CTCAE_v5 ctcae5:C143736 A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and/or warmth. A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and/or warmth. Paresthesia Paresthesia, CTCAE 10033987 C143736 Paresthesia Paresthesia A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and/or warmth. NCI A disorder characterized by functional disturbances of sensory neurons resulting in abnormal cutaneous sensations of tingling, numbness, pressure, cold, and/or warmth. CTCAE_v5 Paresthesia PT CTCAE_v5 Paresthesia, CTCAE PT NCI ctcae5:C143737 A disorder characterized by an infectious process involving the soft tissues around the nail. A disorder characterized by an infectious process involving the soft tissues around the nail. Paronychia Paronychia, CTCAE 10034016 C143737 Paronychia Paronychia A disorder characterized by an infectious process involving the soft tissues around the nail. NCI A disorder characterized by an infectious process involving the soft tissues around the nail. CTCAE_v5 Paronychia PT CTCAE_v5 Paronychia, CTCAE PT NCI ctcae5:C143738 A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. Paroxysmal Atrial Tachycardia, CTCAE Paroxysmal atrial tachycardia 10034040 C143738 Paroxysmal atrial tachycardia Paroxysmal atrial tachycardia A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. NCI A disorder characterized by a dysrhythmia with abrupt onset and sudden termination of atrial contractions with a rate of 150-250 beats per minute. The rhythm disturbance originates in the atria. CTCAE_v5 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C143739 A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. Pelvic Floor Muscle Weakness, CTCAE Pelvic floor muscle weakness 10064026 C143739 Pelvic floor muscle weakness Pelvic floor muscle weakness A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. NCI A disorder characterized by a reduction in the strength of the muscles of the pelvic floor. CTCAE_v5 Pelvic Floor Muscle Weakness, CTCAE PT NCI Pelvic floor muscle weakness PT CTCAE_v5 ctcae5:C143740 A disorder characterized by an infectious process involving the pelvic cavity. A disorder characterized by an infectious process involving the pelvic cavity. Pelvic Infection, CTCAE Pelvic infection 10058674 C143740 Pelvic infection Pelvic infection A disorder characterized by an infectious process involving the pelvic cavity. NCI A disorder characterized by an infectious process involving the pelvic cavity. CTCAE_v5 Pelvic Infection, CTCAE PT NCI Pelvic infection PT CTCAE_v5 ctcae5:C143741 A disorder characterized by an infectious process involving the penis. A disorder characterized by an infectious process involving the penis. Penile Infection, CTCAE Penile infection 10061912 C143741 Penile infection Penile infection A disorder characterized by an infectious process involving the penis. NCI A disorder characterized by an infectious process involving the penis. CTCAE_v5 Penile Infection, CTCAE PT NCI Penile infection PT CTCAE_v5 ctcae5:C143742 A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. Perforation Bile Duct, CTCAE Perforation bile duct 10034405 C143742 Perforation bile duct Perforation bile duct A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. NCI A disorder characterized by a rupture in the wall of the extrahepatic or intrahepatic bile duct. CTCAE_v5 Perforation Bile Duct, CTCAE PT NCI Perforation bile duct PT CTCAE_v5 ctcae5:C143743 A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. Pericardial Effusion, CTCAE Pericardial effusion 10034474 C143743 Pericardial effusion Pericardial effusion A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. NCI A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation. CTCAE_v5 Pericardial Effusion, CTCAE PT NCI Pericardial effusion PT CTCAE_v5 ctcae5:C143744 A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. Pericardial Tamponade, CTCAE Pericardial tamponade 10053565 C143744 Pericardial tamponade Pericardial tamponade A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. NCI A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the pericardium. CTCAE_v5 Pericardial Tamponade, CTCAE PT NCI Pericardial tamponade PT CTCAE_v5 ctcae5:C143747 A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. Periorbital Edema, CTCAE Periorbital edema 10054541 C143747 Periorbital edema Periorbital edema A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. NCI A disorder characterized by swelling due to an excessive accumulation of fluid around the orbits of the face. CTCAE_v5 Periorbital Edema, CTCAE PT NCI Periorbital edema PT CTCAE_v5 ctcae5:C143748 A disorder characterized by an infectious process involving the orbit of the eye. A disorder characterized by an infectious process involving the orbit of the eye. Periorbital Infection, CTCAE Periorbital infection 10051472 C143748 Periorbital infection Periorbital infection A disorder characterized by an infectious process involving the orbit of the eye. NCI A disorder characterized by an infectious process involving the orbit of the eye. CTCAE_v5 Periorbital Infection, CTCAE PT NCI Periorbital infection PT CTCAE_v5 ctcae5:C143749 A disorder characterized by impaired circulation to an extremity. A disorder characterized by impaired circulation to an extremity. Peripheral Ischemia, CTCAE Peripheral ischemia 10034578 C143749 Peripheral ischemia Peripheral ischemia A disorder characterized by impaired circulation to an extremity. NCI A disorder characterized by impaired circulation to an extremity. CTCAE_v5 Peripheral Ischemia, CTCAE PT NCI Peripheral ischemia PT CTCAE_v5 ctcae5:C143750 A disorder characterized by damage or dysfunction of the peripheral motor nerves. A disorder characterized by damage or dysfunction of the peripheral motor nerves. Peripheral Motor Neuropathy, CTCAE Peripheral motor neuropathy 10034580 C143750 Peripheral motor neuropathy Peripheral motor neuropathy A disorder characterized by damage or dysfunction of the peripheral motor nerves. NCI A disorder characterized by damage or dysfunction of the peripheral motor nerves. CTCAE_v5 Peripheral Motor Neuropathy, CTCAE PT NCI Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C143751 A disorder characterized by an infectious process involving the peripheral nerves. A disorder characterized by an infectious process involving the peripheral nerves. Peripheral Nerve Infection, CTCAE Peripheral nerve infection 10065766 C143751 Peripheral nerve infection Peripheral nerve infection A disorder characterized by an infectious process involving the peripheral nerves. NCI A disorder characterized by an infectious process involving the peripheral nerves. CTCAE_v5 Peripheral Nerve Infection, CTCAE PT NCI Peripheral nerve infection PT CTCAE_v5 ctcae5:C143752 A disorder characterized by damage or dysfunction of the peripheral sensory nerves. A disorder characterized by damage or dysfunction of the peripheral sensory nerves. Peripheral Sensory Neuropathy, CTCAE Peripheral sensory neuropathy 10034620 C143752 Peripheral sensory neuropathy Peripheral sensory neuropathy A disorder characterized by damage or dysfunction of the peripheral sensory nerves. NCI A disorder characterized by damage or dysfunction of the peripheral sensory nerves. CTCAE_v5 Peripheral Sensory Neuropathy, CTCAE PT NCI Peripheral sensory neuropathy PT CTCAE_v5 ctcae5:C143753 A disorder characterized by an infectious process involving the peritoneum. A disorder characterized by an infectious process involving the peritoneum. Peritoneal Infection, CTCAE Peritoneal infection 10057262 C143753 Peritoneal infection Peritoneal infection A disorder characterized by an infectious process involving the peritoneum. NCI A disorder characterized by an infectious process involving the peritoneum. CTCAE_v5 Peritoneal Infection, CTCAE PT NCI Peritoneal infection PT CTCAE_v5 ctcae5:C143754 A disorder characterized by a conspicuous change in a person's behavior and thinking. A disorder characterized by a conspicuous change in a person's behavior and thinking. Personality Change, CTCAE Personality change 10034719 C143754 Personality change Personality change A disorder characterized by a conspicuous change in a person's behavior and thinking. NCI A disorder characterized by a conspicuous change in a person's behavior and thinking. CTCAE_v5 Personality Change, CTCAE PT NCI Personality change PT CTCAE_v5 ctcae5:C143755 A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). Pharyngeal Anastomotic Leak, CTCAE Pharyngeal anastomotic leak 10065705 C143755 Pharyngeal anastomotic leak Pharyngeal anastomotic leak A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a pharyngeal anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Pharyngeal Anastomotic Leak, CTCAE PT NCI Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C143756 A disorder characterized by ulceration or inflammation involving the mucous membrane of the pharynx. A disorder characterized by ulceration or inflammation involving the mucous membrane of the pharynx. Pharyngeal Mucositis, CTCAE Pharyngeal mucositis 10065881 C143756 Pharyngeal mucositis Pharyngeal mucositis A disorder characterized by ulceration or inflammation involving the mucous membrane of the pharynx. NCI A disorder characterized by ulceration or inflammation involving the mucous membrane of the pharynx. CTCAE_v5 Pharyngeal Mucositis, CTCAE PT NCI Pharyngeal mucositis PT CTCAE_v5 ctcae5:C143757 A disorder characterized by a narrowing of the pharyngeal airway. A disorder characterized by a narrowing of the pharyngeal airway. Pharyngeal Stenosis, CTCAE Pharyngeal stenosis 10050028 C143757 Pharyngeal stenosis Pharyngeal stenosis A disorder characterized by a narrowing of the pharyngeal airway. NCI A disorder characterized by a narrowing of the pharyngeal airway. CTCAE_v5 Pharyngeal Stenosis, CTCAE PT NCI Pharyngeal stenosis PT CTCAE_v5 ctcae5:C143758 A disorder characterized by inflammation of the throat. A disorder characterized by inflammation of the throat. Pharyngitis Pharyngitis, CTCAE 10034835 C143758 Pharyngitis Pharyngitis A disorder characterized by inflammation of the throat. NCI A disorder characterized by inflammation of the throat. CTCAE_v5 Pharyngitis PT CTCAE_v5 Pharyngitis, CTCAE PT NCI ctcae5:C143759 A disorder characterized by a sensation of marked discomfort in the pharyngolaryngeal region. A disorder characterized by a sensation of marked discomfort in the pharyngolaryngeal region. Pharyngolaryngeal Pain, CTCAE Pharyngolaryngeal pain 10034844 C143759 Pharyngolaryngeal pain Pharyngolaryngeal pain A disorder characterized by a sensation of marked discomfort in the pharyngolaryngeal region. NCI A disorder characterized by a sensation of marked discomfort in the pharyngolaryngeal region. CTCAE_v5 Pharyngolaryngeal Pain, CTCAE PT NCI Pharyngolaryngeal pain PT CTCAE_v5 ctcae5:C143760 A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. Phlebitis Infective, CTCAE Phlebitis infective 10056627 C143760 Phlebitis infective Phlebitis infective A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. NCI A disorder characterized by an infectious process involving the vein. Clinical manifestations include erythema, marked discomfort, swelling, and induration along the course of the infected vein. CTCAE_v5 Phlebitis Infective, CTCAE PT NCI Phlebitis infective PT CTCAE_v5 ctcae5:C143761 A disorder characterized by inflammation of the wall of a vein. A disorder characterized by inflammation of the wall of a vein. Phlebitis Phlebitis, CTCAE 10034879 C143761 Phlebitis Phlebitis A disorder characterized by inflammation of the wall of a vein. NCI A disorder characterized by inflammation of the wall of a vein. CTCAE_v5 Phlebitis PT CTCAE_v5 Phlebitis, CTCAE PT NCI ctcae5:C143764 A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. Platelet Count Decreased, CTCAE Platelet count decreased 10035528 C143764 Platelet count decreased Platelet count decreased A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. NCI A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen. CTCAE_v5 Platelet Count Decreased, CTCAE PT NCI Platelet count decreased PT CTCAE_v5 ctcae5:C143765 A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. Pleural Effusion, CTCAE Pleural effusion 10035598 C143765 Pleural effusion Pleural effusion A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. NCI A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. CTCAE_v5 Pleural Effusion, CTCAE PT NCI Pleural effusion PT CTCAE_v5 ctcae5:C143766 A disorder characterized by an infectious process involving the pleura. A disorder characterized by an infectious process involving the pleura. Pleural Infection, CTCAE Pleural infection 10061351 C143766 Pleural infection Pleural infection A disorder characterized by an infectious process involving the pleura. NCI A disorder characterized by an infectious process involving the pleura. CTCAE_v5 Pleural Infection, CTCAE PT NCI Pleural infection PT CTCAE_v5 ctcae5:C143767 A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. Pneumonitis Pneumonitis, CTCAE 10035742 C143767 Pneumonitis Pneumonitis A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. NCI A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma. CTCAE_v5 Pneumonitis PT CTCAE_v5 Pneumonitis, CTCAE PT NCI ctcae5:C143769 A disorder characterized by an increase in blood pressure in the portal venous system. A disorder characterized by an increase in blood pressure in the portal venous system. Portal Hypertension, CTCAE Portal hypertension 10036200 C143769 Portal hypertension Portal hypertension A disorder characterized by an increase in blood pressure in the portal venous system. NCI A disorder characterized by an increase in blood pressure in the portal venous system. CTCAE_v5 Portal Hypertension, CTCAE PT NCI Portal hypertension PT CTCAE_v5 ctcae5:C143770 A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. Portal Vein Thrombosis, CTCAE Portal vein thrombosis 10036206 C143770 Portal vein thrombosis Portal vein thrombosis A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. NCI A disorder characterized by the formation of a thrombus (blood clot) in the portal vein. CTCAE_v5 Portal Vein Thrombosis, CTCAE PT NCI Portal vein thrombosis PT CTCAE_v5 ctcae5:C143771 A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. Postnasal Drip, CTCAE Postnasal drip 10036402 C143771 Postnasal drip Postnasal drip A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. NCI A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore throat and/or coughing. CTCAE_v5 Postnasal Drip, CTCAE PT NCI Postnasal drip PT CTCAE_v5 ctcae5:C143772 A disorder characterized by bleeding occurring after a surgical procedure. A disorder characterized by bleeding occurring after a surgical procedure. Postoperative Hemorrhage, CTCAE Postoperative hemorrhage 10055322 C143772 Postoperative hemorrhage Postoperative hemorrhage A disorder characterized by bleeding occurring after a surgical procedure. NCI A disorder characterized by bleeding occurring after a surgical procedure. CTCAE_v5 Postoperative Hemorrhage, CTCAE PT NCI Postoperative hemorrhage PT CTCAE_v5 ctcae5:C143773 A finding of a previously undocumented problem that occurs after a thoracic procedure. A finding of a previously undocumented problem that occurs after a thoracic procedure. Postoperative Thoracic Procedure Complication, CTCAE Postoperative thoracic procedure complication 10056745 C143773 Postoperative thoracic procedure complication Postoperative thoracic procedure complication A finding of a previously undocumented problem that occurs after a thoracic procedure. NCI A finding of a previously undocumented problem that occurs after a thoracic procedure. CTCAE_v5 Postoperative Thoracic Procedure Complication, CTCAE PT NCI Postoperative thoracic procedure complication PT CTCAE_v5 ctcae5:C143775 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C143775 Pregnancy, puerperium and perinatal conditions - Other, specify Pregnancy, puerperium and perinatal conditions - Other, specify Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C143776 A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. Premature Delivery, CTCAE Premature delivery 10036595 C143776 Premature delivery Premature delivery A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. NCI A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation. CTCAE_v5 Premature Delivery, CTCAE PT NCI Premature delivery PT CTCAE_v5 ctcae5:C143777 A disorder characterized by premature ovarian failure. Symptoms may include hot flashes, night sweats, mood swings, and a decrease in sex drive. Laboratory findings include elevated luteinizing hormone (LH) and follicle-stimulating hormone (FSH.) A disorder characterized by premature ovarian failure. Symptoms may include hot flashes, night sweats, mood swings, and a decrease in sex drive. Laboratory findings include elevated luteinizing hormone (LH) and follicle-stimulating hormone (FSH.) Premature Menopause, CTCAE Premature menopause 10036601 C143777 Premature menopause Premature menopause A disorder characterized by premature ovarian failure. Symptoms may include hot flashes, night sweats, mood swings, and a decrease in sex drive. Laboratory findings include elevated luteinizing hormone (LH) and follicle-stimulating hormone (FSH.) NCI A disorder characterized by premature ovarian failure. Symptoms may include hot flashes, night sweats, mood swings, and a decrease in sex drive. Laboratory findings include elevated luteinizing hormone (LH) and follicle-stimulating hormone (FSH.) CTCAE_v5 Premature Menopause, CTCAE PT NCI Premature menopause PT CTCAE_v5 ctcae5:C143778 A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. Presyncope Presyncope, CTCAE 10036653 C143778 Presyncope Presyncope A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. NCI A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. CTCAE_v5 Presyncope PT CTCAE_v5 Presyncope, CTCAE PT NCI ctcae5:C143780 A disorder characterized by expectorated secretions upon coughing. A disorder characterized by expectorated secretions upon coughing. Productive Cough, CTCAE Productive cough 10036790 C143780 Productive cough Productive cough A disorder characterized by expectorated secretions upon coughing. NCI A disorder characterized by expectorated secretions upon coughing. CTCAE_v5 Productive Cough, CTCAE PT NCI Productive cough PT CTCAE_v5 ctcae5:C143781 A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. Prolapse of Intestinal Stoma, CTCAE Prolapse of intestinal stoma 10065745 C143781 Prolapse of intestinal stoma Prolapse of intestinal stoma A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. NCI A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the abdominal surface. CTCAE_v5 Prolapse of Intestinal Stoma, CTCAE PT NCI Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C143782 A finding of displacement of the urostomy. A finding of displacement of the urostomy. Prolapse of Urostomy, CTCAE Prolapse of urostomy 10065822 C143782 Prolapse of urostomy Prolapse of urostomy A finding of displacement of the urostomy. NCI A finding of displacement of the urostomy. CTCAE_v5 Prolapse of Urostomy, CTCAE PT NCI Prolapse of urostomy PT CTCAE_v5 ctcae5:C143783 A disorder characterized by an infectious process involving the prostate gland. A disorder characterized by an infectious process involving the prostate gland. Prostate Infection, CTCAE Prostate infection 10050662 C143783 Prostate infection Prostate infection A disorder characterized by an infectious process involving the prostate gland. NCI A disorder characterized by an infectious process involving the prostate gland. CTCAE_v5 Prostate Infection, CTCAE PT NCI Prostate infection PT CTCAE_v5 ctcae5:C143784 A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). Prostatic Obstruction, CTCAE Prostatic obstruction 10055026 C143784 Prostatic obstruction Prostatic obstruction A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). NCI A disorder characterized by compression of the urethra secondary to enlargement of the prostate gland. This results in voiding difficulties (straining to void, slow urine stream, and incomplete emptying of the bladder). CTCAE_v5 Prostatic Obstruction, CTCAE PT NCI Prostatic obstruction PT CTCAE_v5 ctcae5:C143787 Psychiatric Disorders - Other, Specify, CTCAE Psychiatric disorders - Other, specify 10037175 C143787 Psychiatric disorders - Other, specify Psychiatric disorders - Other, specify Psychiatric Disorders - Other, Specify, CTCAE PT NCI Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C143788 A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. Psychosis Psychosis, CTCAE 10037234 C143788 Psychosis Psychosis A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. NCI A disorder characterized by personality change, impaired functioning, and loss of touch with reality. It may be a manifestation of schizophrenia, bipolar disorder or brain tumor. CTCAE_v5 Psychosis PT CTCAE_v5 Psychosis, CTCAE PT NCI ctcae5:C143789 A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. Pulmonary Edema, CTCAE Pulmonary edema 10037375 C143789 Pulmonary edema Pulmonary edema A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. NCI A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure. CTCAE_v5 Pulmonary Edema, CTCAE PT NCI Pulmonary edema PT CTCAE_v5 ctcae5:C143790 A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. Pulmonary Fibrosis, CTCAE Pulmonary fibrosis 10037383 C143790 Pulmonary fibrosis Pulmonary fibrosis A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. NCI A disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure or right heart failure. CTCAE_v5 Pulmonary Fibrosis, CTCAE PT NCI Pulmonary fibrosis PT CTCAE_v5 ctcae5:C143791 A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. Pulmonary Fistula, CTCAE Pulmonary fistula 10065873 C143791 Pulmonary fistula Pulmonary fistula A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the lung and another organ or anatomic site. CTCAE_v5 Pulmonary Fistula, CTCAE PT NCI Pulmonary fistula PT CTCAE_v5 ctcae5:C143793 A disorder characterized by a defect in pulmonary valve function or structure. A disorder characterized by a defect in pulmonary valve function or structure. Pulmonary Valve Disease, CTCAE Pulmonary valve disease 10061541 C143793 Pulmonary valve disease Pulmonary valve disease A disorder characterized by a defect in pulmonary valve function or structure. NCI A disorder characterized by a defect in pulmonary valve function or structure. CTCAE_v5 Pulmonary Valve Disease, CTCAE PT NCI Pulmonary valve disease PT CTCAE_v5 ctcae5:C143794 A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. Purpura Purpura, CTCAE 10037549 C143794 Purpura Purpura A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. NCI A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. CTCAE_v5 Purpura PT CTCAE_v5 Purpura, CTCAE PT NCI ctcae5:C143795 A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. Pyramidal Tract Syndrome, CTCAE Pyramidal tract syndrome 10063636 C143795 Pyramidal tract syndrome Pyramidal tract syndrome A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. NCI A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination. CTCAE_v5 Pyramidal Tract Syndrome, CTCAE PT NCI Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C143796 A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. Radiation Recall Reaction (Dermatologic), CTCAE Radiation recall reaction (dermatologic) 10037767 C143796 Radiation recall reaction (dermatologic) Radiation recall reaction (dermatologic) A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. NCI A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent. CTCAE_v5 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C143797 A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. Radiculitis Radiculitis, CTCAE 10061928 C143797 Radiculitis Radiculitis A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. NCI A disorder characterized by inflammation involving a nerve root. Patients experience marked discomfort radiating along a nerve path because of spinal pressure on the connecting nerve root. CTCAE_v5 Radiculitis PT CTCAE_v5 Radiculitis, CTCAE PT NCI ctcae5:C143798 A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. Rash Acneiform, CTCAE Rash acneiform 10037847 C143798 Rash acneiform Rash acneiform A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. NCI A disorder characterized by an eruption of papules and pustules, typically appearing in face, scalp, upper chest and back. CTCAE_v5 Rash Acneiform, CTCAE PT NCI Rash acneiform PT CTCAE_v5 ctcae5:C143799 A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis. A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis. Rash Maculo-Papular, CTCAE Rash maculo-papular 10037868 C143799 Rash maculo-papular Rash maculo-papular A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis. NCI A disorder characterized by the presence of macules (flat) and papules (elevated). Also known as morbillform rash, it is one of the most common cutaneous adverse events, frequently affecting the upper trunk, spreading centripetally and associated with pruritis. CTCAE_v5 Rash Maculo-Papular, CTCAE PT NCI Rash maculo-papular PT CTCAE_v5 ctcae5:C143800 A disorder characterized by a circumscribed and elevated skin lesion filled with pus. A disorder characterized by a circumscribed and elevated skin lesion filled with pus. Rash Pustular, CTCAE Rash pustular 10037888 C143800 Rash pustular Rash pustular A disorder characterized by a circumscribed and elevated skin lesion filled with pus. NCI A disorder characterized by a circumscribed and elevated skin lesion filled with pus. CTCAE_v5 Rash Pustular, CTCAE PT NCI Rash pustular PT CTCAE_v5 ctcae5:C143801 A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). Rectal Anastomotic Leak, CTCAE Rectal anastomotic leak 10065894 C143801 Rectal anastomotic leak Rectal anastomotic leak A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a rectal anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Rectal Anastomotic Leak, CTCAE PT NCI Rectal anastomotic leak PT CTCAE_v5 ctcae5:C143802 A disorder characterized by ulceration or inflammation of the mucous membrane of the rectum. A disorder characterized by ulceration or inflammation of the mucous membrane of the rectum. Rectal Mucositis, CTCAE Rectal mucositis 10063190 C143802 Rectal mucositis Rectal mucositis A disorder characterized by ulceration or inflammation of the mucous membrane of the rectum. NCI A disorder characterized by ulceration or inflammation of the mucous membrane of the rectum. CTCAE_v5 Rectal Mucositis, CTCAE PT NCI Rectal mucositis PT CTCAE_v5 ctcae5:C143803 A disorder characterized by a narrowing of the lumen of the rectum. A disorder characterized by a narrowing of the lumen of the rectum. Rectal Stenosis, CTCAE Rectal stenosis 10038079 C143803 Rectal stenosis Rectal stenosis A disorder characterized by a narrowing of the lumen of the rectum. NCI A disorder characterized by a narrowing of the lumen of the rectum. CTCAE_v5 Rectal Stenosis, CTCAE PT NCI Rectal stenosis PT CTCAE_v5 ctcae5:C143804 A disorder characterized by paralysis of the recurrent laryngeal nerve. A disorder characterized by paralysis of the recurrent laryngeal nerve. Recurrent Laryngeal Nerve Palsy, CTCAE Recurrent laryngeal nerve palsy 10038130 C143804 Recurrent laryngeal nerve palsy Recurrent laryngeal nerve palsy A disorder characterized by paralysis of the recurrent laryngeal nerve. NCI A disorder characterized by paralysis of the recurrent laryngeal nerve. CTCAE_v5 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C143805 Renal and Urinary Disorders - Other, Specify, CTCAE Renal and urinary disorders - Other, specify 10038359 C143805 Renal and urinary disorders - Other, specify Renal and urinary disorders - Other, specify Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C143806 A disorder characterized by the formation of crystals/kidney stones in the pelvis of the kidney. A disorder characterized by the formation of crystals/kidney stones in the pelvis of the kidney. Renal Calculi, CTCAE Renal calculi 10038385 C143806 Renal calculi Renal calculi A disorder characterized by the formation of crystals/kidney stones in the pelvis of the kidney. NCI A disorder characterized by the formation of crystals/kidney stones in the pelvis of the kidney. CTCAE_v5 Renal Calculi, CTCAE PT NCI Renal calculi PT CTCAE_v5 ctcae5:C143807 A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of crystals/kidney stones. A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of crystals/kidney stones. Renal Colic, CTCAE Renal colic 10038419 C143807 Renal colic Renal colic A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of crystals/kidney stones. NCI A disorder characterized by paroxysmal and severe flank marked discomfort radiating to the inguinal area. Often, the cause is the passage of crystals/kidney stones. CTCAE_v5 Renal Colic, CTCAE PT NCI Renal colic PT CTCAE_v5 ctcae5:C143808 Reproductive System and Breast Disorders - Other, Specify, CTCAE Reproductive system and breast disorders - Other, specify 10038604 C143808 Reproductive system and breast disorders - Other, specify Reproductive system and breast disorders - Other, specify Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C143809 A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. Respiratory Failure, CTCAE Respiratory failure 10038695 C143809 Respiratory failure Respiratory failure A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. NCI A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. CTCAE_v5 Respiratory Failure, CTCAE PT NCI Respiratory failure PT CTCAE_v5 ctcae5:C143810 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C143810 Respiratory, thoracic and mediastinal disorders - Other, specify Respiratory, thoracic and mediastinal disorders - Other, specify Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C143811 A disorder characterized by an inability to rest, relax or be still. A disorder characterized by an inability to rest, relax or be still. Restlessness Restlessness, CTCAE 10038743 C143811 Restlessness Restlessness A disorder characterized by an inability to rest, relax or be still. NCI A disorder characterized by an inability to rest, relax or be still. CTCAE_v5 Restlessness PT CTCAE_v5 Restlessness, CTCAE PT NCI ctcae5:C143814 A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. Retinal Tear, CTCAE Retinal tear 10038897 C143814 Retinal tear Retinal tear A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. NCI A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters. CTCAE_v5 Retinal Tear, CTCAE PT NCI Retinal tear PT CTCAE_v5 ctcae5:C143815 A disorder characterized by pathological retinal blood vessels that adversely affects vision. A disorder characterized by pathological retinal blood vessels that adversely affects vision. Retinal Vascular Disorder, CTCAE Retinal vascular disorder 10038901 C143815 Retinal vascular disorder Retinal vascular disorder A disorder characterized by pathological retinal blood vessels that adversely affects vision. NCI A disorder characterized by pathological retinal blood vessels that adversely affects vision. CTCAE_v5 Retinal Vascular Disorder, CTCAE PT NCI Retinal vascular disorder PT CTCAE_v5 ctcae5:C143818 A disorder characterized by headaches, mental status changes, visual disturbances, and/or seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. Also known as posterior reversible encephalopathy syndrome (PRES). A disorder characterized by headaches, mental status changes, visual disturbances, and/or seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. Also known as posterior reversible encephalopathy syndrome (PRES). Reversible Posterior Leukoencephalopathy Syndrome, CTCAE Reversible posterior leukoencephalopathy syndrome 10063761 C143818 Reversible posterior leukoencephalopathy syndrome Reversible posterior leukoencephalopathy syndrome A disorder characterized by headaches, mental status changes, visual disturbances, and/or seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. Also known as posterior reversible encephalopathy syndrome (PRES). NCI A disorder characterized by headaches, mental status changes, visual disturbances, and/or seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. Also known as posterior reversible encephalopathy syndrome (PRES). CTCAE_v5 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE PT NCI Reversible posterior leukoencephalopathy syndrome PT CTCAE_v5 ctcae5:C143819 A disorder characterized by an infectious process involving the nasal mucosal. A disorder characterized by an infectious process involving the nasal mucosal. Rhinitis Infective, CTCAE Rhinitis infective 10059827 C143819 Rhinitis infective Rhinitis infective A disorder characterized by an infectious process involving the nasal mucosal. NCI A disorder characterized by an infectious process involving the nasal mucosal. CTCAE_v5 Rhinitis Infective, CTCAE PT NCI Rhinitis infective PT CTCAE_v5 ctcae5:C143821 A disorder characterized by inflammation of the salivary duct. A disorder characterized by inflammation of the salivary duct. Salivary Duct Inflammation, CTCAE Salivary duct inflammation 10056681 C143821 Salivary duct inflammation Salivary duct inflammation A disorder characterized by inflammation of the salivary duct. NCI A disorder characterized by inflammation of the salivary duct. CTCAE_v5 Salivary Duct Inflammation, CTCAE PT NCI Salivary duct inflammation PT CTCAE_v5 ctcae5:C143822 A disorder characterized by an infectious process involving the salivary gland. A disorder characterized by an infectious process involving the salivary gland. Salivary Gland Infection, CTCAE Salivary gland infection 10039413 C143822 Salivary gland infection Salivary gland infection A disorder characterized by an infectious process involving the salivary gland. NCI A disorder characterized by an infectious process involving the salivary gland. CTCAE_v5 Salivary Gland Infection, CTCAE PT NCI Salivary gland infection PT CTCAE_v5 ctcae5:C143823 A disorder characterized by involvement of the sclera of the eye. A disorder characterized by involvement of the sclera of the eye. Scleral Disorder, CTCAE Scleral disorder 10061510 C143823 Scleral disorder Scleral disorder A disorder characterized by involvement of the sclera of the eye. NCI A disorder characterized by involvement of the sclera of the eye. CTCAE_v5 Scleral Disorder, CTCAE PT NCI Scleral disorder PT CTCAE_v5 ctcae5:C143824 A disorder characterized by a malformed, lateral curvature of the spine. A disorder characterized by a malformed, lateral curvature of the spine. Scoliosis Scoliosis, CTCAE 10039722 C143824 Scoliosis Scoliosis A disorder characterized by a malformed, lateral curvature of the spine. NCI A disorder characterized by a malformed, lateral curvature of the spine. CTCAE_v5 Scoliosis PT CTCAE_v5 Scoliosis, CTCAE PT NCI ctcae5:C143825 A disorder characterized by an infectious process involving the scrotum. A disorder characterized by an infectious process involving the scrotum. Scrotal Infection, CTCAE Scrotal infection 10062156 C143825 Scrotal infection Scrotal infection A disorder characterized by an infectious process involving the scrotum. NCI A disorder characterized by an infectious process involving the scrotum. CTCAE_v5 Scrotal Infection, CTCAE PT NCI Scrotal infection PT CTCAE_v5 ctcae5:C143827 A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. Sepsis Sepsis, CTCAE 10040047 C143827 Sepsis Sepsis A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. NCI A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock. CTCAE_v5 Sepsis PT CTCAE_v5 Sepsis, CTCAE PT NCI ctcae5:C143829 A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. Serum Amylase Increased, CTCAE Serum amylase increased 10040139 C143829 Serum amylase increased Serum amylase increased A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. NCI A finding based on laboratory test results that indicate an increase in the levels of amylase in a serum specimen. CTCAE_v5 Serum Amylase Increased, CTCAE PT NCI Serum amylase increased PT CTCAE_v5 ctcae5:C143831 A disorder characterized by involvement of the paranasal sinuses. A disorder characterized by involvement of the paranasal sinuses. Sinus Disorder, CTCAE Sinus disorder 10062244 C143831 Sinus disorder Sinus disorder A disorder characterized by involvement of the paranasal sinuses. NCI A disorder characterized by involvement of the paranasal sinuses. CTCAE_v5 Sinus Disorder, CTCAE PT NCI Sinus disorder PT CTCAE_v5 ctcae5:C143832 A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. Sinusitis Sinusitis, CTCAE 10040753 C143832 Sinusitis Sinusitis A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. NCI A disorder characterized by an infectious process involving the mucous membranes of the paranasal sinuses. CTCAE_v5 Sinusitis PT CTCAE_v5 Sinusitis, CTCAE PT NCI ctcae5:C143833 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Skin and subcutaneous tissue disorders - Other, specify 10040785 C143833 Skin and subcutaneous tissue disorders - Other, specify Skin and subcutaneous tissue disorders - Other, specify Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C143835 A disorder characterized by darkening of the skin due to excessive melanin deposition. A disorder characterized by darkening of the skin due to excessive melanin deposition. Skin Hyperpigmentation, CTCAE Skin hyperpigmentation 10040865 C143835 Skin hyperpigmentation Skin hyperpigmentation A disorder characterized by darkening of the skin due to excessive melanin deposition. NCI A disorder characterized by darkening of the skin due to excessive melanin deposition. CTCAE_v5 Skin Hyperpigmentation, CTCAE PT NCI Skin hyperpigmentation PT CTCAE_v5 ctcae5:C143836 A disorder characterized by loss of skin pigment (e.g., vitiligo). A disorder characterized by loss of skin pigment (e.g., vitiligo). Skin Hypopigmentation, CTCAE Skin hypopigmentation 10040868 C143836 Skin hypopigmentation Skin hypopigmentation A disorder characterized by loss of skin pigment (e.g., vitiligo). NCI A disorder characterized by loss of skin pigment (e.g., vitiligo). CTCAE_v5 Skin Hypopigmentation, CTCAE PT NCI Skin hypopigmentation PT CTCAE_v5 ctcae5:C143837 A disorder characterized by an area of hardness in the skin. A disorder characterized by an area of hardness in the skin. Skin Induration, CTCAE Skin induration 10051837 C143837 Skin induration Skin induration A disorder characterized by an area of hardness in the skin. NCI A disorder characterized by an area of hardness in the skin. CTCAE_v5 Skin Induration, CTCAE PT NCI Skin induration PT CTCAE_v5 ctcae5:C143838 A disorder characterized by an infectious process involving the skin such as cellulitis. A disorder characterized by an infectious process involving the skin such as cellulitis. Skin Infection, CTCAE Skin infection 10040872 C143838 Skin infection Skin infection A disorder characterized by an infectious process involving the skin such as cellulitis. NCI A disorder characterized by an infectious process involving the skin such as cellulitis. CTCAE_v5 Skin Infection, CTCAE PT NCI Skin infection PT CTCAE_v5 ctcae5:C143839 A disorder characterized by a circumscribed, erosive lesion on the skin. A disorder characterized by a circumscribed, erosive lesion on the skin. Skin Ulceration, CTCAE Skin ulceration 10040947 C143839 Skin ulceration Skin ulceration A disorder characterized by a circumscribed, erosive lesion on the skin. NCI A disorder characterized by a circumscribed, erosive lesion on the skin. CTCAE_v5 Skin Ulceration, CTCAE PT NCI Skin ulceration PT CTCAE_v5 ctcae5:C143840 A disorder characterized by cessation of breathing for short periods during sleep. A disorder characterized by cessation of breathing for short periods during sleep. Sleep Apnea, CTCAE Sleep apnea 10040975 C143840 Sleep apnea Sleep apnea A disorder characterized by cessation of breathing for short periods during sleep. NCI A disorder characterized by cessation of breathing for short periods during sleep. CTCAE_v5 Sleep Apnea, CTCAE PT NCI Sleep apnea PT CTCAE_v5 ctcae5:C143841 A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. Small Intestinal Anastomotic Leak, CTCAE Small intestinal anastomotic leak 10065892 C143841 Small intestinal anastomotic leak Small intestinal anastomotic leak A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. NCI A finding of leakage due to breakdown of an anastomosis (surgical connection of two separate anatomic structures) in the small bowel. CTCAE_v5 Small Intestinal Anastomotic Leak, CTCAE PT NCI Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C143842 A disorder characterized by ulceration or inflammation of the mucous membrane of the small intestine. A disorder characterized by ulceration or inflammation of the mucous membrane of the small intestine. Small Intestinal Mucositis, CTCAE Small intestinal mucositis 10065710 C143842 Small intestinal mucositis Small intestinal mucositis A disorder characterized by ulceration or inflammation of the mucous membrane of the small intestine. NCI A disorder characterized by ulceration or inflammation of the mucous membrane of the small intestine. CTCAE_v5 Small Intestinal Mucositis, CTCAE PT NCI Small intestinal mucositis PT CTCAE_v5 ctcae5:C143843 A disorder characterized by blockage of the normal flow of the intestinal contents of the small intestine. A disorder characterized by blockage of the normal flow of the intestinal contents of the small intestine. Small Intestinal Obstruction, CTCAE Small intestinal obstruction 10041101 C143843 Small intestinal obstruction Small intestinal obstruction A disorder characterized by blockage of the normal flow of the intestinal contents of the small intestine. NCI A disorder characterized by blockage of the normal flow of the intestinal contents of the small intestine. CTCAE_v5 Small Intestinal Obstruction, CTCAE PT NCI Small intestinal obstruction PT CTCAE_v5 ctcae5:C143844 A disorder characterized by a narrowing of the lumen of the small intestine. A disorder characterized by a narrowing of the lumen of the small intestine. Small Intestinal Stenosis, CTCAE Small intestinal stenosis 10062263 C143844 Small intestinal stenosis Small intestinal stenosis A disorder characterized by a narrowing of the lumen of the small intestine. NCI A disorder characterized by a narrowing of the lumen of the small intestine. CTCAE_v5 Small Intestinal Stenosis, CTCAE PT NCI Small intestinal stenosis PT CTCAE_v5 ctcae5:C143845 A disorder characterized by an infectious process involving the small intestine. A disorder characterized by an infectious process involving the small intestine. Small Intestine Infection, CTCAE Small intestine infection 10065771 C143845 Small intestine infection Small intestine infection A disorder characterized by an infectious process involving the small intestine. NCI A disorder characterized by an infectious process involving the small intestine. CTCAE_v5 Small Intestine Infection, CTCAE PT NCI Small intestine infection PT CTCAE_v5 ctcae5:C143846 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the small intestine. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the small intestine. Small Intestine Ulcer, CTCAE Small intestine ulcer 10041133 C143846 Small intestine ulcer Small intestine ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the small intestine. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the small intestine. CTCAE_v5 Small Intestine Ulcer, CTCAE PT NCI Small intestine ulcer PT CTCAE_v5 ctcae5:C143847 A disorder characterized by the involuntary expulsion of air from the nose. A disorder characterized by the involuntary expulsion of air from the nose. Sneezing Sneezing, CTCAE 10041232 C143847 Sneezing Sneezing A disorder characterized by the involuntary expulsion of air from the nose. NCI A disorder characterized by the involuntary expulsion of air from the nose. CTCAE_v5 Sneezing PT CTCAE_v5 Sneezing, CTCAE PT NCI ctcae5:C143848 Social Circumstances - Other, Specify, CTCAE Social circumstances - Other, specify 10041244 C143848 Social circumstances - Other, specify Social circumstances - Other, specify Social Circumstances - Other, Specify, CTCAE PT NCI Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C143849 A disorder characterized by an infectious process involving soft tissues. A disorder characterized by an infectious process involving soft tissues. Soft Tissue Infection, CTCAE Soft tissue infection 10062255 C143849 Soft tissue infection Soft tissue infection A disorder characterized by an infectious process involving soft tissues. NCI A disorder characterized by an infectious process involving soft tissues. CTCAE_v5 Soft Tissue Infection, CTCAE PT NCI Soft tissue infection PT CTCAE_v5 ctcae5:C143850 A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. Soft Tissue Necrosis Lower Limb, CTCAE Soft tissue necrosis lower limb 10065777 C143850 Soft tissue necrosis lower limb Soft tissue necrosis lower limb A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the lower extremity. CTCAE_v5 Soft Tissue Necrosis Lower Limb, CTCAE PT NCI Soft tissue necrosis lower limb PT CTCAE_v5 ctcae5:C143851 A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. Soft Tissue Necrosis Upper Limb, CTCAE Soft tissue necrosis upper limb 10065778 C143851 Soft tissue necrosis upper limb Soft tissue necrosis upper limb A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the upper extremity. CTCAE_v5 Soft Tissue Necrosis Upper Limb, CTCAE PT NCI Soft tissue necrosis upper limb PT CTCAE_v5 ctcae5:C143852 A disorder characterized by characterized by excessive sleepiness and drowsiness. A disorder characterized by characterized by excessive sleepiness and drowsiness. Somnolence Somnolence, CTCAE 10041349 C143852 Somnolence Somnolence A disorder characterized by characterized by excessive sleepiness and drowsiness. NCI A disorder characterized by characterized by excessive sleepiness and drowsiness. CTCAE_v5 Somnolence PT CTCAE_v5 Somnolence, CTCAE PT NCI ctcae5:C143853 A disorder characterized by marked discomfort in the throat A disorder characterized by marked discomfort in the throat Sore Throat, CTCAE Sore throat 10041367 C143853 Sore throat Sore throat A disorder characterized by marked discomfort in the throat NCI A disorder characterized by marked discomfort in the throat CTCAE_v5 Sore Throat, CTCAE PT NCI Sore throat PT CTCAE_v5 ctcae5:C143854 A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. Spasticity Spasticity, CTCAE 10041416 C143854 Spasticity Spasticity A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. NCI A disorder characterized by increased involuntary muscle tone that affects the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. CTCAE_v5 Spasticity PT CTCAE_v5 Spasticity, CTCAE PT NCI ctcae5:C143855 A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). Spermatic Cord Anastomotic Leak, CTCAE Spermatic cord anastomotic leak 10065897 C143855 Spermatic cord anastomotic leak Spermatic cord anastomotic leak A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a spermatic cord anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C143856 A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. Spinal Fracture, CTCAE Spinal fracture 10041569 C143856 Spinal fracture Spinal fracture A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. NCI A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken. CTCAE_v5 Spinal Fracture, CTCAE PT NCI Spinal fracture PT CTCAE_v5 ctcae5:C143857 A disorder characterized by an infectious process involving the spleen. A disorder characterized by an infectious process involving the spleen. Splenic Infection, CTCAE Splenic infection 10062112 C143857 Splenic infection Splenic infection A disorder characterized by an infectious process involving the spleen. NCI A disorder characterized by an infectious process involving the spleen. CTCAE_v5 Splenic Infection, CTCAE PT NCI Splenic infection PT CTCAE_v5 ctcae5:C143858 A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). Stenosis of Gastrointestinal Stoma, CTCAE Stenosis of gastrointestinal stoma 10065898 C143858 Stenosis of gastrointestinal stoma Stenosis of gastrointestinal stoma A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). NCI A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body). CTCAE_v5 Stenosis of Gastrointestinal Stoma, CTCAE PT NCI Stenosis of gastrointestinal stoma PT CTCAE_v5 ctcae5:C143859 A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. Stevens-Johnson Syndrome, CTCAE Stevens-Johnson syndrome 10042033 C143859 Stevens-Johnson syndrome Stevens-Johnson syndrome A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. NCI A disorder characterized by less than 10% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. CTCAE_v5 Stevens-Johnson Syndrome, CTCAE PT NCI Stevens-Johnson syndrome PT CTCAE_v5 ctcae5:C143860 A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). Stoma Site Infection, CTCAE Stoma site infection 10064505 C143860 Stoma site infection Stoma site infection A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). NCI A disorder characterized by an infectious process involving a stoma (surgically created opening on the surface of the body). CTCAE_v5 Stoma Site Infection, CTCAE PT NCI Stoma site infection PT CTCAE_v5 ctcae5:C143861 A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. Stridor Stridor, CTCAE 10042241 C143861 Stridor Stridor A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. NCI A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction. CTCAE_v5 Stridor PT CTCAE_v5 Stridor, CTCAE PT NCI ctcae5:C143862 A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. Stroke Stroke, CTCAE 10042244 C143862 Stroke Stroke A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. NCI A disorder characterized by a decrease or absence of blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurological damage. CTCAE_v5 Stroke PT CTCAE_v5 Stroke, CTCAE PT NCI ctcae5:C143863 An unexpected death that cannot be attributed to a CTCAE term associated with Grade 5. An unexpected death that cannot be attributed to a CTCAE term associated with Grade 5. Sudden Death NOS, CTCAE Sudden death NOS 10042435 C143863 Sudden death NOS Sudden death NOS An unexpected death that cannot be attributed to a CTCAE term associated with Grade 5. NCI An unexpected death that cannot be attributed to a CTCAE term associated with Grade 5. CTCAE_v5 Sudden Death NOS, CTCAE PT NCI Sudden death NOS PT CTCAE_v5 ctcae5:C143864 A disorder characterized by thoughts of taking one's own life. A disorder characterized by thoughts of taking one's own life. Suicidal Ideation, CTCAE Suicidal ideation 10042458 C143864 Suicidal ideation Suicidal ideation A disorder characterized by thoughts of taking one's own life. NCI A disorder characterized by thoughts of taking one's own life. CTCAE_v5 Suicidal Ideation, CTCAE PT NCI Suicidal ideation PT CTCAE_v5 ctcae5:C143865 A disorder characterized by self-inflicted harm in an attempt to end one's own life. A disorder characterized by self-inflicted harm in an attempt to end one's own life. Suicide Attempt, CTCAE Suicide attempt 10042464 C143865 Suicide attempt Suicide attempt A disorder characterized by self-inflicted harm in an attempt to end one's own life. NCI A disorder characterized by self-inflicted harm in an attempt to end one's own life. CTCAE_v5 Suicide Attempt, CTCAE PT NCI Suicide attempt PT CTCAE_v5 ctcae5:C143866 A disorder characterized by fibrotic degeneration of the superficial soft tissues. A disorder characterized by fibrotic degeneration of the superficial soft tissues. Superficial Soft Tissue Fibrosis, CTCAE Superficial soft tissue fibrosis 10065798 C143866 Superficial soft tissue fibrosis Superficial soft tissue fibrosis A disorder characterized by fibrotic degeneration of the superficial soft tissues. NCI A disorder characterized by fibrotic degeneration of the superficial soft tissues. CTCAE_v5 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C143867 A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. Superficial Thrombophlebitis, CTCAE Superficial thrombophlebitis 10042554 C143867 Superficial thrombophlebitis Superficial thrombophlebitis A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. NCI A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities. CTCAE_v5 Superficial Thrombophlebitis, CTCAE PT NCI Superficial thrombophlebitis PT CTCAE_v5 ctcae5:C143868 A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. Superior Vena Cava Syndrome, CTCAE Superior vena cava syndrome 10042569 C143868 Superior vena cava syndrome Superior vena cava syndrome A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. NCI A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache. CTCAE_v5 Superior Vena Cava Syndrome, CTCAE PT NCI Superior vena cava syndrome PT CTCAE_v5 ctcae5:C143869 Surgical and Medical Procedures - Other, Specify, CTCAE Surgical and medical procedures - Other, specify 10042613 C143869 Surgical and medical procedures - Other, specify Surgical and medical procedures - Other, specify Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C143872 A disorder characterized by abnormal function or appearance of the testis. A disorder characterized by abnormal function or appearance of the testis. Testicular Disorder, CTCAE Testicular disorder 10043306 C143872 Testicular disorder Testicular disorder A disorder characterized by abnormal function or appearance of the testis. NCI A disorder characterized by abnormal function or appearance of the testis. CTCAE_v5 Testicular Disorder, CTCAE PT NCI Testicular disorder PT CTCAE_v5 ctcae5:C143873 A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. Thromboembolic Event, CTCAE Thromboembolic event 10043565 C143873 Thromboembolic event Thromboembolic event A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. NCI A disorder characterized by occlusion of a vessel by a thrombus that has migrated from a distal site via the blood stream. CTCAE_v5 Thromboembolic Event, CTCAE PT NCI Thromboembolic event PT CTCAE_v5 ctcae5:C143874 A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. Thrombotic Thrombocytopenic Purpura, CTCAE Thrombotic thrombocytopenic purpura 10043648 C143874 Thrombotic thrombocytopenic purpura Thrombotic thrombocytopenic purpura A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. NCI A disorder characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition. CTCAE_v5 Thrombotic Thrombocytopenic Purpura, CTCAE PT NCI Thrombotic thrombocytopenic purpura PT CTCAE_v5 ctcae5:C143876 A disorder characterized by a pathological process of the teeth occurring during tooth development. A disorder characterized by a pathological process of the teeth occurring during tooth development. Tooth Development Disorder, CTCAE Tooth development disorder 10044030 C143876 Tooth development disorder Tooth development disorder A disorder characterized by a pathological process of the teeth occurring during tooth development. NCI A disorder characterized by a pathological process of the teeth occurring during tooth development. CTCAE_v5 Tooth Development Disorder, CTCAE PT NCI Tooth development disorder PT CTCAE_v5 ctcae5:C143877 A disorder characterized by a change in tooth hue or tint. A disorder characterized by a change in tooth hue or tint. Tooth Discoloration, CTCAE Tooth discoloration 10044031 C143877 Tooth discoloration Tooth discoloration A disorder characterized by a change in tooth hue or tint. NCI A disorder characterized by a change in tooth hue or tint. CTCAE_v5 Tooth Discoloration, CTCAE PT NCI Tooth discoloration PT CTCAE_v5 ctcae5:C143878 A disorder characterized by an infectious process involving a tooth. A disorder characterized by an infectious process involving a tooth. Tooth Infection, CTCAE Tooth infection 10048762 C143878 Tooth infection Tooth infection A disorder characterized by an infectious process involving a tooth. NCI A disorder characterized by an infectious process involving a tooth. CTCAE_v5 Tooth Infection, CTCAE PT NCI Tooth infection PT CTCAE_v5 ctcae5:C143879 A disorder characterized by a sensation of marked discomfort in the tooth. A disorder characterized by a sensation of marked discomfort in the tooth. Toothache Toothache, CTCAE 10044055 C143879 Toothache Toothache A disorder characterized by a sensation of marked discomfort in the tooth. NCI A disorder characterized by a sensation of marked discomfort in the tooth. CTCAE_v5 Toothache PT CTCAE_v5 Toothache, CTCAE PT NCI ctcae5:C143880 A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. Toxic Epidermal Necrolysis, CTCAE Toxic epidermal necrolysis 10044223 C143880 Toxic epidermal necrolysis Toxic epidermal necrolysis A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. NCI A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes. CTCAE_v5 Toxic Epidermal Necrolysis, CTCAE PT NCI Toxic epidermal necrolysis PT CTCAE_v5 ctcae5:C143881 A disorder characterized by an inflammation or ulceration involving the mucous membrane of the trachea. A disorder characterized by an inflammation or ulceration involving the mucous membrane of the trachea. Tracheal Mucositis, CTCAE Tracheal mucositis 10065900 C143881 Tracheal mucositis Tracheal mucositis A disorder characterized by an inflammation or ulceration involving the mucous membrane of the trachea. NCI A disorder characterized by an inflammation or ulceration involving the mucous membrane of the trachea. CTCAE_v5 Tracheal Mucositis, CTCAE PT NCI Tracheal mucositis PT CTCAE_v5 ctcae5:C143882 A disorder characterized by blockage of the lumen of the trachea. A disorder characterized by blockage of the lumen of the trachea. Tracheal Obstruction, CTCAE Tracheal obstruction 10044291 C143882 Tracheal obstruction Tracheal obstruction A disorder characterized by blockage of the lumen of the trachea. NCI A disorder characterized by blockage of the lumen of the trachea. CTCAE_v5 Tracheal Obstruction, CTCAE PT NCI Tracheal obstruction PT CTCAE_v5 ctcae5:C143883 A disorder characterized by a narrowing of the trachea. A disorder characterized by a narrowing of the trachea. Tracheal Stenosis, CTCAE Tracheal stenosis 10050816 C143883 Tracheal stenosis Tracheal stenosis A disorder characterized by a narrowing of the trachea. NCI A disorder characterized by a narrowing of the trachea. CTCAE_v5 Tracheal Stenosis, CTCAE PT NCI Tracheal stenosis PT CTCAE_v5 ctcae5:C143884 A disorder characterized by an infectious process involving the trachea. A disorder characterized by an infectious process involving the trachea. Tracheitis Tracheitis, CTCAE 10044302 C143884 Tracheitis Tracheitis A disorder characterized by an infectious process involving the trachea. NCI A disorder characterized by an infectious process involving the trachea. CTCAE_v5 Tracheitis PT CTCAE_v5 Tracheitis, CTCAE PT NCI ctcae5:C143885 A disorder characterized by bleeding from the tracheostomy site. A disorder characterized by bleeding from the tracheostomy site. Tracheostomy Site Bleeding, CTCAE Tracheostomy site bleeding 10065749 C143885 Tracheostomy site bleeding Tracheostomy site bleeding A disorder characterized by bleeding from the tracheostomy site. NCI A disorder characterized by bleeding from the tracheostomy site. CTCAE_v5 Tracheostomy Site Bleeding, CTCAE PT NCI Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C143886 A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. Transient Ischemic Attacks, CTCAE Transient ischemic attacks 10044391 C143886 Transient ischemic attacks Transient ischemic attacks A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. NCI A disorder characterized by a brief attack (less than 24 hours) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. CTCAE_v5 Transient Ischemic Attacks, CTCAE PT NCI Transient ischemic attacks PT CTCAE_v5 ctcae5:C143887 A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. Treatment Related Secondary Malignancy, CTCAE Treatment related secondary malignancy 10049737 C143887 Treatment related secondary malignancy Treatment related secondary malignancy A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. NCI A disorder characterized by development of a malignancy most probably as a result of treatment for a previously existing malignancy. CTCAE_v5 Treatment Related Secondary Malignancy, CTCAE PT NCI Treatment related secondary malignancy PT CTCAE_v5 ctcae5:C143889 A disorder characterized by a defect in tricuspid valve function or structure. A disorder characterized by a defect in tricuspid valve function or structure. Tricuspid Valve Disease, CTCAE Tricuspid valve disease 10061389 C143889 Tricuspid valve disease Tricuspid valve disease A disorder characterized by a defect in tricuspid valve function or structure. NCI A disorder characterized by a defect in tricuspid valve function or structure. CTCAE_v5 Tricuspid Valve Disease, CTCAE PT NCI Tricuspid valve disease PT CTCAE_v5 ctcae5:C143890 A disorder characterized by dysfunction of the trigeminal nerve (fifth cranial nerve). A disorder characterized by dysfunction of the trigeminal nerve (fifth cranial nerve). Trigeminal Nerve Disorder, CTCAE Trigeminal nerve disorder 10060890 C143890 Trigeminal nerve disorder Trigeminal nerve disorder A disorder characterized by dysfunction of the trigeminal nerve (fifth cranial nerve). NCI A disorder characterized by dysfunction of the trigeminal nerve (fifth cranial nerve). CTCAE_v5 Trigeminal Nerve Disorder, CTCAE PT NCI Trigeminal nerve disorder PT CTCAE_v5 ctcae5:C143894 A disorder characterized by a discrepancy between the lengths of the lower or upper extremities. A disorder characterized by a discrepancy between the lengths of the lower or upper extremities. Unequal Limb Length, CTCAE Unequal limb length 10065738 C143894 Unequal limb length Unequal limb length A disorder characterized by a discrepancy between the lengths of the lower or upper extremities. NCI A disorder characterized by a discrepancy between the lengths of the lower or upper extremities. CTCAE_v5 Unequal Limb Length, CTCAE PT NCI Unequal limb length PT CTCAE_v5 ctcae5:C143895 A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). Upper Gastrointestinal Hemorrhage, CTCAE Upper gastrointestinal hemorrhage 10055356 C143895 Upper gastrointestinal hemorrhage Upper gastrointestinal hemorrhage A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). NCI A disorder characterized by bleeding from the upper gastrointestinal tract (oral cavity, pharynx, esophagus, and stomach). CTCAE_v5 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C143896 A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). Upper Respiratory Infection, CTCAE Upper respiratory infection 10046300 C143896 Upper respiratory infection Upper respiratory infection A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). NCI A disorder characterized by an infectious process involving the upper respiratory tract (nose, paranasal sinuses, pharynx, larynx, or trachea). CTCAE_v5 Upper Respiratory Infection, CTCAE PT NCI Upper respiratory infection PT CTCAE_v5 ctcae5:C143897 A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). Ureteric Anastomotic Leak, CTCAE Ureteric anastomotic leak 10065814 C143897 Ureteric anastomotic leak Ureteric anastomotic leak A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a ureteral anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Ureteric Anastomotic Leak, CTCAE PT NCI Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C143898 A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). Urethral Anastomotic Leak, CTCAE Urethral anastomotic leak 10065815 C143898 Urethral anastomotic leak Urethral anastomotic leak A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a urethral anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Urethral Anastomotic Leak, CTCAE PT NCI Urethral anastomotic leak PT CTCAE_v5 ctcae5:C143899 A disorder characterized by an infectious process involving the urethra. A disorder characterized by an infectious process involving the urethra. Urethral Infection, CTCAE Urethral infection 10052298 C143899 Urethral infection Urethral infection A disorder characterized by an infectious process involving the urethra. NCI A disorder characterized by an infectious process involving the urethra. CTCAE_v5 Urethral Infection, CTCAE PT NCI Urethral infection PT CTCAE_v5 ctcae5:C143900 A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. Urinary Fistula, CTCAE Urinary fistula 10065368 C143900 Urinary fistula Urinary fistula A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between any part of the urinary system and another organ or anatomic site. CTCAE_v5 Urinary Fistula, CTCAE PT NCI Urinary fistula PT CTCAE_v5 ctcae5:C143901 A disorder characterized by urination at short intervals. A disorder characterized by urination at short intervals. Urinary Frequency, CTCAE Urinary frequency 10046539 C143901 Urinary frequency Urinary frequency A disorder characterized by urination at short intervals. NCI A disorder characterized by urination at short intervals. CTCAE_v5 Urinary Frequency, CTCAE PT NCI Urinary frequency PT CTCAE_v5 ctcae5:C143904 A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. Urinary Tract Infection, CTCAE Urinary tract infection 10046571 C143904 Urinary tract infection Urinary tract infection A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. NCI A disorder characterized by an infectious process involving the urinary tract, most commonly the bladder and the urethra. CTCAE_v5 Urinary Tract Infection, CTCAE PT NCI Urinary tract infection PT CTCAE_v5 ctcae5:C143905 A disorder characterized by blockage of the normal flow of contents of the urinary tract. A disorder characterized by blockage of the normal flow of contents of the urinary tract. Urinary Tract Obstruction, CTCAE Urinary tract obstruction 10061574 C143905 Urinary tract obstruction Urinary tract obstruction A disorder characterized by blockage of the normal flow of contents of the urinary tract. NCI A disorder characterized by blockage of the normal flow of contents of the urinary tract. CTCAE_v5 Urinary Tract Obstruction, CTCAE PT NCI Urinary tract obstruction PT CTCAE_v5 ctcae5:C143906 A disorder characterized by a sensation of marked discomfort in the urinary tract. A disorder characterized by a sensation of marked discomfort in the urinary tract. Urinary Tract Pain, CTCAE Urinary tract pain 10062225 C143906 Urinary tract pain Urinary tract pain A disorder characterized by a sensation of marked discomfort in the urinary tract. NCI A disorder characterized by a sensation of marked discomfort in the urinary tract. CTCAE_v5 Urinary Tract Pain, CTCAE PT NCI Urinary tract pain PT CTCAE_v5 ctcae5:C143907 A disorder characterized by a sudden compelling urge to urinate. A disorder characterized by a sudden compelling urge to urinate. Urinary Urgency, CTCAE Urinary urgency 10046593 C143907 Urinary urgency Urinary urgency A disorder characterized by a sudden compelling urge to urinate. NCI A disorder characterized by a sudden compelling urge to urinate. CTCAE_v5 Urinary Urgency, CTCAE PT NCI Urinary urgency PT CTCAE_v5 ctcae5:C143908 A disorder characterized by a change in the color of the urine. A disorder characterized by a change in the color of the urine. Urine Discoloration, CTCAE Urine discoloration 10046628 C143908 Urine discoloration Urine discoloration A disorder characterized by a change in the color of the urine. NCI A disorder characterized by a change in the color of the urine. CTCAE_v5 Urine Discoloration, CTCAE PT NCI Urine discoloration PT CTCAE_v5 ctcae5:C143909 A finding based on test results that indicate urine production is less relative to previous output. A finding based on test results that indicate urine production is less relative to previous output. Urine Output Decreased, CTCAE Urine output decreased 10059895 C143909 Urine output decreased Urine output decreased A finding based on test results that indicate urine production is less relative to previous output. NCI A finding based on test results that indicate urine production is less relative to previous output. CTCAE_v5 Urine Output Decreased, CTCAE PT NCI Urine output decreased PT CTCAE_v5 ctcae5:C143910 A finding of leakage of contents from a urostomy. A finding of leakage of contents from a urostomy. Urostomy Leak, CTCAE Urostomy leak 10065882 C143910 Urostomy leak Urostomy leak A finding of leakage of contents from a urostomy. NCI A finding of leakage of contents from a urostomy. CTCAE_v5 Urostomy Leak, CTCAE PT NCI Urostomy leak PT CTCAE_v5 ctcae5:C143911 A disorder characterized by blockage of the urostomy. A disorder characterized by blockage of the urostomy. Urostomy Obstruction, CTCAE Urostomy obstruction 10065883 C143911 Urostomy obstruction Urostomy obstruction A disorder characterized by blockage of the urostomy. NCI A disorder characterized by blockage of the urostomy. CTCAE_v5 Urostomy Obstruction, CTCAE PT NCI Urostomy obstruction PT CTCAE_v5 ctcae5:C143912 A disorder characterized by bleeding from the urostomy site. A disorder characterized by bleeding from the urostomy site. Urostomy Site Bleeding, CTCAE Urostomy site bleeding 10065748 C143912 Urostomy site bleeding Urostomy site bleeding A disorder characterized by bleeding from the urostomy site. NCI A disorder characterized by bleeding from the urostomy site. CTCAE_v5 Urostomy Site Bleeding, CTCAE PT NCI Urostomy site bleeding PT CTCAE_v5 ctcae5:C143913 A finding of narrowing of the opening of a urostomy. A finding of narrowing of the opening of a urostomy. Urostomy Stenosis, CTCAE Urostomy stenosis 10065885 C143913 Urostomy stenosis Urostomy stenosis A finding of narrowing of the opening of a urostomy. NCI A finding of narrowing of the opening of a urostomy. CTCAE_v5 Urostomy Stenosis, CTCAE PT NCI Urostomy stenosis PT CTCAE_v5 ctcae5:C143915 A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). Uterine Anastomotic Leak, CTCAE Uterine anastomotic leak 10065886 C143915 Uterine anastomotic leak Uterine anastomotic leak A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a uterine anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Uterine Anastomotic Leak, CTCAE PT NCI Uterine anastomotic leak PT CTCAE_v5 ctcae5:C143916 A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. Uterine Fistula, CTCAE Uterine fistula 10065811 C143916 Uterine fistula Uterine fistula A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the uterus and another organ or anatomic site. CTCAE_v5 Uterine Fistula, CTCAE PT NCI Uterine fistula PT CTCAE_v5 ctcae5:C143917 A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. Uterine Infection, CTCAE Uterine infection 10062233 C143917 Uterine infection Uterine infection A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. NCI A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues. CTCAE_v5 Uterine Infection, CTCAE PT NCI Uterine infection PT CTCAE_v5 ctcae5:C143918 A disorder characterized by blockage of the uterine outlet. A disorder characterized by blockage of the uterine outlet. Uterine Obstruction, CTCAE Uterine obstruction 10065928 C143918 Uterine obstruction Uterine obstruction A disorder characterized by blockage of the uterine outlet. NCI A disorder characterized by blockage of the uterine outlet. CTCAE_v5 Uterine Obstruction, CTCAE PT NCI Uterine obstruction PT CTCAE_v5 ctcae5:C143919 A disorder characterized by a rupture in the uterine wall. A disorder characterized by a rupture in the uterine wall. Uterine Perforation, CTCAE Uterine perforation 10046810 C143919 Uterine perforation Uterine perforation A disorder characterized by a rupture in the uterine wall. NCI A disorder characterized by a rupture in the uterine wall. CTCAE_v5 Uterine Perforation, CTCAE PT NCI Uterine perforation PT CTCAE_v5 ctcae5:C143921 A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). Vaginal Anastomotic Leak, CTCAE Vaginal anastomotic leak 10065887 C143921 Vaginal anastomotic leak Vaginal anastomotic leak A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a vaginal anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Vaginal Anastomotic Leak, CTCAE PT NCI Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C143922 A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. Vaginal Discharge, CTCAE Vaginal discharge 10046901 C143922 Vaginal discharge Vaginal discharge A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. NCI A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years. CTCAE_v5 Vaginal Discharge, CTCAE PT NCI Vaginal discharge PT CTCAE_v5 ctcae5:C143924 A disorder characterized by an infectious process involving the vagina. A disorder characterized by an infectious process involving the vagina. Vaginal Infection, CTCAE Vaginal infection 10046914 C143924 Vaginal infection Vaginal infection A disorder characterized by an infectious process involving the vagina. NCI A disorder characterized by an infectious process involving the vagina. CTCAE_v5 Vaginal Infection, CTCAE PT NCI Vaginal infection PT CTCAE_v5 ctcae5:C143925 A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. Vaginal Inflammation, CTCAE Vaginal inflammation 10046916 C143925 Vaginal inflammation Vaginal inflammation A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. NCI A disorder characterized by inflammation involving the vagina. Symptoms may include redness, edema, marked discomfort and an increase in vaginal discharge. CTCAE_v5 Vaginal Inflammation, CTCAE PT NCI Vaginal inflammation PT CTCAE_v5 ctcae5:C143926 A disorder characterized by a narrowing of the vaginal canal. A disorder characterized by a narrowing of the vaginal canal. Vaginal Stricture, CTCAE Vaginal stricture 10053496 C143926 Vaginal stricture Vaginal stricture A disorder characterized by a narrowing of the vaginal canal. NCI A disorder characterized by a narrowing of the vaginal canal. CTCAE_v5 Vaginal Stricture, CTCAE PT NCI Vaginal stricture PT CTCAE_v5 ctcae5:C143927 A disorder characterized by dysfunction of the vagus nerve (tenth cranial nerve). A disorder characterized by dysfunction of the vagus nerve (tenth cranial nerve). Vagus Nerve Disorder, CTCAE Vagus nerve disorder 10061403 C143927 Vagus nerve disorder Vagus nerve disorder A disorder characterized by dysfunction of the vagus nerve (tenth cranial nerve). NCI A disorder characterized by dysfunction of the vagus nerve (tenth cranial nerve). CTCAE_v5 Vagus Nerve Disorder, CTCAE PT NCI Vagus nerve disorder PT CTCAE_v5 ctcae5:C143928 A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). Vas Deferens Anastomotic Leak, CTCAE Vas deferens anastomotic leak 10065888 C143928 Vas deferens anastomotic leak Vas deferens anastomotic leak A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). NCI A finding of leakage due to breakdown of a vas deferens anastomosis (surgical connection of two separate anatomic structures). CTCAE_v5 Vas Deferens Anastomotic Leak, CTCAE PT NCI Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C143929 A finding of a previously undocumented problem related to the vascular access site. A finding of a previously undocumented problem related to the vascular access site. Vascular Access Complication, CTCAE Vascular access complication 10062169 C143929 Vascular access complication Vascular access complication A finding of a previously undocumented problem related to the vascular access site. NCI A finding of a previously undocumented problem related to the vascular access site. CTCAE_v5 Vascular Access Complication, CTCAE PT NCI Vascular access complication PT CTCAE_v5 ctcae5:C143930 Vascular Disorders - Other, Specify, CTCAE Vascular disorders - Other, specify 10047065 C143930 Vascular disorders - Other, specify Vascular disorders - Other, specify Vascular Disorders - Other, Specify, CTCAE PT NCI Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C143932 A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. Vasovagal Reaction, CTCAE Vasovagal reaction 10047166 C143932 Vasovagal reaction Vasovagal reaction A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. NCI A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve. CTCAE_v5 Vasovagal Reaction, CTCAE PT NCI Vasovagal reaction PT CTCAE_v5 ctcae5:C143933 A finding of damage to a vein. A finding of damage to a vein. Venous Injury, CTCAE Venous injury 10047228 C143933 Venous injury Venous injury A finding of damage to a vein. NCI A finding of damage to a vein. CTCAE_v5 Venous Injury, CTCAE PT NCI Venous injury PT CTCAE_v5 ctcae5:C143935 A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). Vertigo Vertigo, CTCAE 10047340 C143935 Vertigo Vertigo A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). NCI A disorder characterized by a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). CTCAE_v5 Vertigo PT CTCAE_v5 Vertigo, CTCAE PT NCI ctcae5:C143936 A disorder characterized by dizziness, imbalance, nausea, and vision problems. A disorder characterized by dizziness, imbalance, nausea, and vision problems. Vestibular Disorder, CTCAE Vestibular disorder 10047386 C143936 Vestibular disorder Vestibular disorder A disorder characterized by dizziness, imbalance, nausea, and vision problems. NCI A disorder characterized by dizziness, imbalance, nausea, and vision problems. CTCAE_v5 Vestibular Disorder, CTCAE PT NCI Vestibular disorder PT CTCAE_v5 ctcae5:C143937 A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. Virilization Virilization, CTCAE 10047488 C143937 Virilization Virilization A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. NCI A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male. CTCAE_v5 Virilization PT CTCAE_v5 Virilization, CTCAE PT NCI ctcae5:C143938 A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. Visceral Arterial Ischemia, CTCAE Visceral arterial ischemia 10054692 C143938 Visceral arterial ischemia Visceral arterial ischemia A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. NCI A disorder characterized by a decrease in blood supply due to narrowing or blockage of a visceral (mesenteric) artery. CTCAE_v5 Visceral Arterial Ischemia, CTCAE PT NCI Visceral arterial ischemia PT CTCAE_v5 ctcae5:C143939 A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. Vital Capacity Abnormal, CTCAE Vital capacity abnormal 10047580 C143939 Vital capacity abnormal Vital capacity abnormal A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. NCI A finding based on pulmonary function test results that indicate an abnormal vital capacity (amount of exhaled after a maximum inhalation) when compared to the predicted value. CTCAE_v5 Vital Capacity Abnormal, CTCAE PT NCI Vital capacity abnormal PT CTCAE_v5 ctcae5:C143941 A disorder characterized by a change in the sound and/or speed of the voice. A disorder characterized by a change in the sound and/or speed of the voice. Voice Alteration, CTCAE Voice alteration 10047681 C143941 Voice alteration Voice alteration A disorder characterized by a change in the sound and/or speed of the voice. NCI A disorder characterized by a change in the sound and/or speed of the voice. CTCAE_v5 Voice Alteration, CTCAE PT NCI Voice alteration PT CTCAE_v5 ctcae5:C143943 A disorder characterized by an infectious process involving the vulva. A disorder characterized by an infectious process involving the vulva. Vulval Infection, CTCAE Vulval infection 10065772 C143943 Vulval infection Vulval infection A disorder characterized by an infectious process involving the vulva. NCI A disorder characterized by an infectious process involving the vulva. CTCAE_v5 Vulval Infection, CTCAE PT NCI Vulval infection PT CTCAE_v5 ctcae5:C143944 A disorder characterized by excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. A disorder characterized by excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. Watering Eyes, CTCAE Watering eyes 10047848 C143944 Watering eyes Watering eyes A disorder characterized by excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. NCI A disorder characterized by excessive tearing in the eyes; it can be caused by overproduction of tears or impaired drainage of the tear duct. CTCAE_v5 Watering Eyes, CTCAE PT NCI Watering eyes PT CTCAE_v5 ctcae5:C143947 A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. Wheezing Wheezing, CTCAE 10047924 C143947 Wheezing Wheezing A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. NCI A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or obstruction of the respiratory airways. CTCAE_v5 Wheezing PT CTCAE_v5 Wheezing, CTCAE PT NCI ctcae5:C143948 A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. White Blood Cell Decreased, CTCAE White blood cell decreased 10049182 C143948 White blood cell decreased White blood cell decreased A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. NCI A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen. CTCAE_v5 White Blood Cell Decreased, CTCAE PT NCI White blood cell decreased PT CTCAE_v5 ctcae5:C143949 A finding of development of a new problem at the site of an existing wound. A finding of development of a new problem at the site of an existing wound. Wound Complication, CTCAE Wound complication 10053692 C143949 Wound complication Wound complication A finding of development of a new problem at the site of an existing wound. NCI A finding of development of a new problem at the site of an existing wound. CTCAE_v5 Wound Complication, CTCAE PT NCI Wound complication PT CTCAE_v5 ctcae5:C143950 A finding of separation of the approximated margins of a surgical wound. A finding of separation of the approximated margins of a surgical wound. Wound Dehiscence, CTCAE Wound dehiscence 10048031 C143950 Wound dehiscence Wound dehiscence A finding of separation of the approximated margins of a surgical wound. NCI A finding of separation of the approximated margins of a surgical wound. CTCAE_v5 Wound Dehiscence, CTCAE PT NCI Wound dehiscence PT CTCAE_v5 ctcae5:C143951 A disorder characterized by an infectious process involving the wound. A disorder characterized by an infectious process involving the wound. Wound Infection, CTCAE Wound infection 10048038 C143951 Wound infection Wound infection A disorder characterized by an infectious process involving the wound. NCI A disorder characterized by an infectious process involving the wound. CTCAE_v5 Wound Infection, CTCAE PT NCI Wound infection PT CTCAE_v5 ctcae5:C143952 A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. Wrist Fracture, CTCAE Wrist fracture 10048049 C143952 Wrist fracture Wrist fracture A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. NCI A finding of traumatic injury to the wrist joint in which the continuity of a wrist bone is broken. CTCAE_v5 Wrist Fracture, CTCAE PT NCI Wrist fracture PT CTCAE_v5 ctcae5:C143958 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Abdominal Distension, CTCAE Grade 1 Abdominal distension 10000060 C143958 Grade 1 Abdominal distension Grade 1 Abdominal distension Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Abdominal Distension, CTCAE PT NCI Grade 1 Abdominal distension PT CTCAE_v5 ctcae5:C143959 Mild pain Mild pain Grade 1 Abdominal Pain, CTCAE Grade 1 Abdominal pain 10000081 C143959 Grade 1 Abdominal pain Grade 1 Abdominal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Abdominal Pain, CTCAE PT NCI Grade 1 Abdominal pain PT CTCAE_v5 ctcae5:C143960 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Abducens Nerve Disorder, CTCAE Grade 1 Abducens nerve disorder 10053662 C143960 Grade 1 Abducens nerve disorder Grade 1 Abducens nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Abducens Nerve Disorder, CTCAE PT NCI Grade 1 Abducens nerve disorder PT CTCAE_v5 ctcae5:C143961 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Accessory Nerve Disorder, CTCAE Grade 1 Accessory nerve disorder 10060929 C143961 Grade 1 Accessory nerve disorder Grade 1 Accessory nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Accessory Nerve Disorder, CTCAE PT NCI Grade 1 Accessory nerve disorder PT CTCAE_v5 ctcae5:C143962 pH <normal, but >=7.3 pH <normal, but >=7.3 Grade 1 Acidosis Grade 1 Acidosis, CTCAE 10000486 C143962 Grade 1 Acidosis Grade 1 Acidosis pH <normal, but >=7.3 NCI pH <normal, but >=7.3 CTCAE_v5 Grade 1 Acidosis PT CTCAE_v5 Grade 1 Acidosis, CTCAE PT NCI ctcae5:C143963 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Acoustic Nerve Disorder NOS, CTCAE Grade 1 Acoustic nerve disorder NOS 10000521 C143963 Grade 1 Acoustic nerve disorder NOS Grade 1 Acoustic nerve disorder NOS Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Acoustic Nerve Disorder NOS, CTCAE PT NCI Grade 1 Acoustic nerve disorder NOS PT CTCAE_v5 ctcae5:C143964 >ULN-1.5 x ULN >ULN-1.5 x ULN Grade 1 Activated Partial Thromboplastin Time Prolonged, CTCAE Grade 1 Activated partial thromboplastin time prolonged 10000636 C143964 Grade 1 Activated partial thromboplastin time prolonged Grade 1 Activated partial thromboplastin time prolonged >ULN-1.5 x ULN NCI >ULN-1.5 x ULN CTCAE_v5 Grade 1 Activated Partial Thromboplastin Time Prolonged, CTCAE PT NCI Grade 1 Activated partial thromboplastin time prolonged PT CTCAE_v5 ctcae5:C143965 Mild restlessness or increased motor activity Mild restlessness or increased motor activity Grade 1 Akathisia Grade 1 Akathisia, CTCAE 10001540 C143965 Grade 1 Akathisia Grade 1 Akathisia Mild restlessness or increased motor activity NCI Mild restlessness or increased motor activity CTCAE_v5 Grade 1 Akathisia PT CTCAE_v5 Grade 1 Akathisia, CTCAE PT NCI ctcae5:C143966 >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal Grade 1 Alanine Aminotransferase Increased, CTCAE Grade 1 Alanine aminotransferase increased 10001551 C143966 Grade 1 Alanine aminotransferase increased Grade 1 Alanine aminotransferase increased >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal NCI >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal CTCAE_v5 Grade 1 Alanine Aminotransferase Increased, CTCAE PT NCI Grade 1 Alanine aminotransferase increased PT CTCAE_v5 ctcae5:C143967 >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal Grade 1 Alkaline Phosphatase Increased, CTCAE Grade 1 Alkaline phosphatase increased 10001675 C143967 Grade 1 Alkaline phosphatase increased Grade 1 Alkaline phosphatase increased >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal NCI >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal CTCAE_v5 Grade 1 Alkaline Phosphatase Increased, CTCAE PT NCI Grade 1 Alkaline phosphatase increased PT CTCAE_v5 ctcae5:C143968 pH >normal, but <=7.5 pH >normal, but <=7.5 Grade 1 Alkalosis Grade 1 Alkalosis, CTCAE 10001680 C143968 Grade 1 Alkalosis Grade 1 Alkalosis pH >normal, but <=7.5 NCI pH >normal, but <=7.5 CTCAE_v5 Grade 1 Alkalosis PT CTCAE_v5 Grade 1 Alkalosis, CTCAE PT NCI ctcae5:C143969 Systemic intervention not indicated Systemic intervention not indicated Grade 1 Allergic Reaction, CTCAE Grade 1 Allergic reaction 10001718 C143969 Grade 1 Allergic reaction Grade 1 Allergic reaction Systemic intervention not indicated NCI Systemic intervention not indicated CTCAE_v5 Grade 1 Allergic Reaction, CTCAE PT NCI Grade 1 Allergic reaction PT CTCAE_v5 ctcae5:C143970 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Allergic Rhinitis, CTCAE Grade 1 Allergic rhinitis 10001723 C143970 Grade 1 Allergic rhinitis Grade 1 Allergic rhinitis Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Allergic Rhinitis, CTCAE PT NCI Grade 1 Allergic rhinitis PT CTCAE_v5 ctcae5:C143971 Mild; transient memory loss Mild; transient memory loss Grade 1 Amnesia Grade 1 Amnesia, CTCAE 10001949 C143971 Grade 1 Amnesia Grade 1 Amnesia Mild; transient memory loss NCI Mild; transient memory loss CTCAE_v5 Grade 1 Amnesia PT CTCAE_v5 Grade 1 Amnesia, CTCAE PT NCI ctcae5:C143972 Asymptomatic Asymptomatic Grade 1 Anal Fissure, CTCAE Grade 1 Anal fissure 10002153 C143972 Grade 1 Anal fissure Grade 1 Anal fissure Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Anal Fissure, CTCAE PT NCI Grade 1 Anal fissure PT CTCAE_v5 ctcae5:C143973 Asymptomatic Asymptomatic Grade 1 Anal Fistula, CTCAE Grade 1 Anal fistula 10002156 C143973 Grade 1 Anal fistula Grade 1 Anal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Anal Fistula, CTCAE PT NCI Grade 1 Anal fistula PT CTCAE_v5 ctcae5:C143974 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Anal Hemorrhage, CTCAE Grade 1 Anal hemorrhage 10055226 C143974 Grade 1 Anal hemorrhage Grade 1 Anal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Anal Hemorrhage, CTCAE PT NCI Grade 1 Anal hemorrhage PT CTCAE_v5 ctcae5:C143975 Asymptomatic or mild symptoms; intervention not indicated Asymptomatic or mild symptoms; intervention not indicated Grade 1 Anal Mucositis, CTCAE Grade 1 Anal mucositis 10065721 C143975 Grade 1 Anal mucositis Grade 1 Anal mucositis Asymptomatic or mild symptoms; intervention not indicated NCI Asymptomatic or mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Anal Mucositis, CTCAE PT NCI Grade 1 Anal mucositis PT CTCAE_v5 ctcae5:C143976 Mild pain Mild pain Grade 1 Anal Pain, CTCAE Grade 1 Anal pain 10002167 C143976 Grade 1 Anal pain Grade 1 Anal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Anal Pain, CTCAE PT NCI Grade 1 Anal pain PT CTCAE_v5 ctcae5:C143977 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Anal Stenosis, CTCAE Grade 1 Anal stenosis 10002176 C143977 Grade 1 Anal stenosis Grade 1 Anal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Anal Stenosis, CTCAE PT NCI Grade 1 Anal stenosis PT CTCAE_v5 ctcae5:C143978 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Anal Ulcer, CTCAE Grade 1 Anal ulcer 10002180 C143978 Grade 1 Anal ulcer Grade 1 Anal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Anal Ulcer, CTCAE PT NCI Grade 1 Anal ulcer PT CTCAE_v5 ctcae5:C143979 Hemoglobin (Hgb) <LLN-10.0 g/dL; <LLN-6.2 mmol/L; <LLN-100 g/L Hemoglobin (Hgb) <LLN-10.0 g/dL; <LLN-6.2 mmol/L; <LLN-100 g/L Grade 1 Anemia Grade 1 Anemia, CTCAE 10002272 C143979 Grade 1 Anemia Grade 1 Anemia Hemoglobin (Hgb) <LLN-10.0 g/dL; <LLN-6.2 mmol/L; <LLN-100 g/L NCI Hemoglobin (Hgb) <LLN-10.0 g/dL; <LLN-6.2 mmol/L; <LLN-100 g/L CTCAE_v5 Grade 1 Anemia PT CTCAE_v5 Grade 1 Anemia, CTCAE PT NCI ctcae5:C143980 Mild; non-operative intervention indicated Mild; non-operative intervention indicated Grade 1 Ankle Fracture, CTCAE Grade 1 Ankle fracture 10002544 C143980 Grade 1 Ankle fracture Grade 1 Ankle fracture Mild; non-operative intervention indicated NCI Mild; non-operative intervention indicated CTCAE_v5 Grade 1 Ankle Fracture, CTCAE PT NCI Grade 1 Ankle fracture PT CTCAE_v5 ctcae5:C143981 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Anorectal Infection, CTCAE Grade 1 Anorectal infection 10061640 C143981 Grade 1 Anorectal infection Grade 1 Anorectal infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Anorectal Infection, CTCAE PT NCI Grade 1 Anorectal infection PT CTCAE_v5 ctcae5:C143982 Inability to achieve orgasm not adversely affecting relationship Inability to achieve orgasm not adversely affecting relationship Grade 1 Anorgasmia Grade 1 Anorgasmia, CTCAE 10002652 C143982 Grade 1 Anorgasmia Grade 1 Anorgasmia Inability to achieve orgasm not adversely affecting relationship NCI Inability to achieve orgasm not adversely affecting relationship CTCAE_v5 Grade 1 Anorgasmia PT CTCAE_v5 Grade 1 Anorgasmia, CTCAE PT NCI ctcae5:C143983 Present Present Grade 1 Anosmia Grade 1 Anosmia, CTCAE 10002653 C143983 Grade 1 Anosmia Grade 1 Anosmia Present NCI Present CTCAE_v5 Grade 1 Anosmia PT CTCAE_v5 Grade 1 Anosmia, CTCAE PT NCI ctcae5:C143984 Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Grade 1 Aortic Valve Disease, CTCAE Grade 1 Aortic valve disease 10061589 C143984 Grade 1 Aortic valve disease Grade 1 Aortic valve disease Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging NCI Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging CTCAE_v5 Grade 1 Aortic Valve Disease, CTCAE PT NCI Grade 1 Aortic valve disease PT CTCAE_v5 ctcae5:C143985 Mild symptoms Mild symptoms Grade 1 Arachnoiditis Grade 1 Arachnoiditis, CTCAE 10003074 C143985 Grade 1 Arachnoiditis Grade 1 Arachnoiditis Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Arachnoiditis PT CTCAE_v5 Grade 1 Arachnoiditis, CTCAE PT NCI ctcae5:C143986 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Arterial Injury, CTCAE Grade 1 Arterial injury 10003162 C143986 Grade 1 Arterial injury Grade 1 Arterial injury Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Arterial Injury, CTCAE PT NCI Grade 1 Arterial injury PT CTCAE_v5 ctcae5:C143987 Mild pain Mild pain Grade 1 Arthralgia Grade 1 Arthralgia, CTCAE 10003239 C143987 Grade 1 Arthralgia Grade 1 Arthralgia Mild pain NCI Mild pain CTCAE_v5 Grade 1 Arthralgia PT CTCAE_v5 Grade 1 Arthralgia, CTCAE PT NCI ctcae5:C143988 Mild pain with inflammation, erythema, or joint swelling Mild pain with inflammation, erythema, or joint swelling Grade 1 Arthritis Grade 1 Arthritis, CTCAE 10003246 C143988 Grade 1 Arthritis Grade 1 Arthritis Mild pain with inflammation, erythema, or joint swelling NCI Mild pain with inflammation, erythema, or joint swelling CTCAE_v5 Grade 1 Arthritis PT CTCAE_v5 Grade 1 Arthritis, CTCAE PT NCI ctcae5:C143989 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ascites Grade 1 Ascites, CTCAE 10003445 C143989 Grade 1 Ascites Grade 1 Ascites Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ascites PT CTCAE_v5 Grade 1 Ascites, CTCAE PT NCI ctcae5:C143990 >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal Grade 1 Aspartate Aminotransferase Increased, CTCAE Grade 1 Aspartate aminotransferase increased 10003481 C143990 Grade 1 Aspartate aminotransferase increased Grade 1 Aspartate aminotransferase increased >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal NCI >ULN-3.0 x ULN if baseline was normal; 1.5-3.0 x baseline if baseline was abnormal CTCAE_v5 Grade 1 Aspartate Aminotransferase Increased, CTCAE PT NCI Grade 1 Aspartate aminotransferase increased PT CTCAE_v5 ctcae5:C143991 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Atrioventricular Block First Degree, CTCAE Grade 1 Atrioventricular block first degree 10003674 C143991 Grade 1 Atrioventricular block first degree Grade 1 Atrioventricular block first degree Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Atrioventricular Block First Degree, CTCAE PT NCI Grade 1 Atrioventricular block first degree PT CTCAE_v5 ctcae5:C143992 Asymptomatic; serologic or other evidence of autoimmune reaction, with normal organ function; intervention not indicated Asymptomatic; serologic or other evidence of autoimmune reaction, with normal organ function; intervention not indicated Grade 1 Autoimmune Disorder, CTCAE Grade 1 Autoimmune disorder 10061664 C143992 Grade 1 Autoimmune disorder Grade 1 Autoimmune disorder Asymptomatic; serologic or other evidence of autoimmune reaction, with normal organ function; intervention not indicated NCI Asymptomatic; serologic or other evidence of autoimmune reaction, with normal organ function; intervention not indicated CTCAE_v5 Grade 1 Autoimmune Disorder, CTCAE PT NCI Grade 1 Autoimmune disorder PT CTCAE_v5 ctcae5:C143993 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Avascular Necrosis, CTCAE Grade 1 Avascular necrosis 10066480 C143993 Grade 1 Avascular necrosis Grade 1 Avascular necrosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Avascular Necrosis, CTCAE PT NCI Grade 1 Avascular necrosis PT CTCAE_v5 ctcae5:C143994 Increase from baseline Increase from baseline Grade 1 Belching Grade 1 Belching, CTCAE 10004222 C143994 Grade 1 Belching Grade 1 Belching Increase from baseline NCI Increase from baseline CTCAE_v5 Grade 1 Belching PT CTCAE_v5 Grade 1 Belching, CTCAE PT NCI ctcae5:C143995 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Bile Duct Stenosis, CTCAE Grade 1 Bile duct stenosis 10051341 C143995 Grade 1 Bile duct stenosis Grade 1 Bile duct stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Bile Duct Stenosis, CTCAE PT NCI Grade 1 Bile duct stenosis PT CTCAE_v5 ctcae5:C143996 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Biliary Anastomotic Leak, CTCAE Grade 1 Biliary anastomotic leak 10050458 C143996 Grade 1 Biliary anastomotic leak Grade 1 Biliary anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Biliary Anastomotic Leak, CTCAE PT NCI Grade 1 Biliary anastomotic leak PT CTCAE_v5 ctcae5:C143997 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Bladder Anastomotic Leak, CTCAE Grade 1 Bladder anastomotic leak 10065802 C143997 Grade 1 Bladder anastomotic leak Grade 1 Bladder anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Bladder Anastomotic Leak, CTCAE PT NCI Grade 1 Bladder anastomotic leak PT CTCAE_v5 ctcae5:C143999 No change in bowel function or oral intake No change in bowel function or oral intake Grade 1 Bloating Grade 1 Bloating, CTCAE 10005265 C143999 Grade 1 Bloating Grade 1 Bloating No change in bowel function or oral intake NCI No change in bowel function or oral intake CTCAE_v5 Grade 1 Bloating PT CTCAE_v5 Grade 1 Bloating, CTCAE PT NCI ctcae5:C144000 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Grade 1 Blood and lymphatic system disorders - Other, specify 10005329 C144000 Grade 1 Blood and lymphatic system disorders - Other, specify Grade 1 Blood and lymphatic system disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Grade 1 Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C144001 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Blood Antidiuretic Hormone Abnormal, CTCAE Grade 1 Blood antidiuretic hormone abnormal 10005332 C144001 Grade 1 Blood antidiuretic hormone abnormal Grade 1 Blood antidiuretic hormone abnormal Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Blood Antidiuretic Hormone Abnormal, CTCAE PT NCI Grade 1 Blood antidiuretic hormone abnormal PT CTCAE_v5 ctcae5:C144002 <LLN and no intervention initiated <LLN and no intervention initiated Grade 1 Blood Bicarbonate Decreased, CTCAE Grade 1 Blood bicarbonate decreased 10005359 C144002 Grade 1 Blood bicarbonate decreased Grade 1 Blood bicarbonate decreased <LLN and no intervention initiated NCI <LLN and no intervention initiated CTCAE_v5 Grade 1 Blood Bicarbonate Decreased, CTCAE PT NCI Grade 1 Blood bicarbonate decreased PT CTCAE_v5 ctcae5:C144003 >ULN-1.5 x ULN if baseline was normal; > 1.0-1.5 x baseline if baseline was abnormal >ULN-1.5 x ULN if baseline was normal; > 1.0-1.5 x baseline if baseline was abnormal Grade 1 Blood Bilirubin Increased, CTCAE Grade 1 Blood bilirubin increased 10005364 C144003 Grade 1 Blood bilirubin increased Grade 1 Blood bilirubin increased >ULN-1.5 x ULN if baseline was normal; > 1.0-1.5 x baseline if baseline was abnormal NCI >ULN-1.5 x ULN if baseline was normal; > 1.0-1.5 x baseline if baseline was abnormal CTCAE_v5 Grade 1 Blood Bilirubin Increased, CTCAE PT NCI Grade 1 Blood bilirubin increased PT CTCAE_v5 ctcae5:C144004 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Blood Corticotrophin Decreased, CTCAE Grade 1 Blood corticotrophin decreased 10005452 C144004 Grade 1 Blood corticotrophin decreased Grade 1 Blood corticotrophin decreased Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Blood Corticotrophin Decreased, CTCAE PT NCI Grade 1 Blood corticotrophin decreased PT CTCAE_v5 ctcae5:C144005 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Blood Gonadotrophin Abnormal, CTCAE Grade 1 Blood gonadotrophin abnormal 10005561 C144005 Grade 1 Blood gonadotrophin abnormal Grade 1 Blood gonadotrophin abnormal Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Blood Gonadotrophin Abnormal, CTCAE PT NCI Grade 1 Blood gonadotrophin abnormal PT CTCAE_v5 ctcae5:C144006 >ULN >ULN Grade 1 Blood Lactate Dehydrogenase Increased, CTCAE Grade 1 Blood lactate dehydrogenase increased 10005630 C144006 Grade 1 Blood lactate dehydrogenase increased Grade 1 Blood lactate dehydrogenase increased >ULN NCI >ULN CTCAE_v5 Grade 1 Blood Lactate Dehydrogenase Increased, CTCAE PT NCI Grade 1 Blood lactate dehydrogenase increased PT CTCAE_v5 ctcae5:C144007 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Blood Prolactin Abnormal, CTCAE Grade 1 Blood prolactin abnormal 10005778 C144007 Grade 1 Blood prolactin abnormal Grade 1 Blood prolactin abnormal Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Blood Prolactin Abnormal, CTCAE PT NCI Grade 1 Blood prolactin abnormal PT CTCAE_v5 ctcae5:C144008 Mild odor; physician intervention not indicated; self care interventions Mild odor; physician intervention not indicated; self care interventions Grade 1 Body Odor, CTCAE Grade 1 Body odor 10005901 C144008 Grade 1 Body odor Grade 1 Body odor Mild odor; physician intervention not indicated; self care interventions NCI Mild odor; physician intervention not indicated; self care interventions CTCAE_v5 Grade 1 Body Odor, CTCAE PT NCI Grade 1 Body odor PT CTCAE_v5 ctcae5:C144009 Mildly hypocellular or <=25% reduction from normal cellularity for age Mildly hypocellular or <=25% reduction from normal cellularity for age Grade 1 Bone Marrow Hypocellular, CTCAE Grade 1 Bone marrow hypocellular 10048580 C144009 Grade 1 Bone marrow hypocellular Grade 1 Bone marrow hypocellular Mildly hypocellular or <=25% reduction from normal cellularity for age NCI Mildly hypocellular or <=25% reduction from normal cellularity for age CTCAE_v5 Grade 1 Bone Marrow Hypocellular, CTCAE PT NCI Grade 1 Bone marrow hypocellular PT CTCAE_v5 ctcae5:C144010 Minimal asymmetry; minimal atrophy Minimal asymmetry; minimal atrophy Grade 1 Breast Atrophy, CTCAE Grade 1 Breast atrophy 10006179 C144010 Grade 1 Breast atrophy Grade 1 Breast atrophy Minimal asymmetry; minimal atrophy NCI Minimal asymmetry; minimal atrophy CTCAE_v5 Grade 1 Breast Atrophy, CTCAE PT NCI Grade 1 Breast atrophy PT CTCAE_v5 ctcae5:C144011 Asymptomatic Asymptomatic Grade 1 Bronchial Fistula, CTCAE Grade 1 Bronchial fistula 10006437 C144011 Grade 1 Bronchial fistula Grade 1 Bronchial fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Bronchial Fistula, CTCAE PT NCI Grade 1 Bronchial fistula PT CTCAE_v5 ctcae5:C144012 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Bronchial Obstruction, CTCAE Grade 1 Bronchial obstruction 10006440 C144012 Grade 1 Bronchial obstruction Grade 1 Bronchial obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Bronchial Obstruction, CTCAE PT NCI Grade 1 Bronchial obstruction PT CTCAE_v5 ctcae5:C144013 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Bronchial Stricture, CTCAE Grade 1 Bronchial stricture 10063524 C144013 Grade 1 Bronchial stricture Grade 1 Bronchial stricture Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Bronchial Stricture, CTCAE PT NCI Grade 1 Bronchial stricture PT CTCAE_v5 ctcae5:C144014 Asymptomatic Asymptomatic Grade 1 Bronchopleural Fistula, CTCAE Grade 1 Bronchopleural fistula 10053481 C144014 Grade 1 Bronchopleural fistula Grade 1 Bronchopleural fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Bronchopleural Fistula, CTCAE PT NCI Grade 1 Bronchopleural fistula PT CTCAE_v5 ctcae5:C144015 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Bronchopulmonary Hemorrhage, CTCAE Grade 1 Bronchopulmonary hemorrhage 10065746 C144015 Grade 1 Bronchopulmonary hemorrhage Grade 1 Bronchopulmonary hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Bronchopulmonary Hemorrhage, CTCAE PT NCI Grade 1 Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C144016 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Bronchospasm Grade 1 Bronchospasm, CTCAE 10006482 C144016 Grade 1 Bronchospasm Grade 1 Bronchospasm Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Bronchospasm PT CTCAE_v5 Grade 1 Bronchospasm, CTCAE PT NCI ctcae5:C144017 Localized or in a dependent area Localized or in a dependent area Grade 1 Bruising Grade 1 Bruising, CTCAE 10006504 C144017 Grade 1 Bruising Grade 1 Bruising Localized or in a dependent area NCI Localized or in a dependent area CTCAE_v5 Grade 1 Bruising PT CTCAE_v5 Grade 1 Bruising, CTCAE PT NCI ctcae5:C144018 Asymptomatic; blisters covering <10% BSA Asymptomatic; blisters covering <10% BSA Grade 1 Bullous Dermatitis, CTCAE Grade 1 Bullous dermatitis 10006556 C144018 Grade 1 Bullous dermatitis Grade 1 Bullous dermatitis Asymptomatic; blisters covering <10% BSA NCI Asymptomatic; blisters covering <10% BSA CTCAE_v5 Grade 1 Bullous Dermatitis, CTCAE PT NCI Grade 1 Bullous dermatitis PT CTCAE_v5 ctcae5:C144019 Asymptomatic Asymptomatic Grade 1 Capillary Leak Syndrome, CTCAE Grade 1 Capillary leak syndrome 10007196 C144019 Grade 1 Capillary leak syndrome Grade 1 Capillary leak syndrome Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Capillary Leak Syndrome, CTCAE PT NCI Grade 1 Capillary leak syndrome PT CTCAE_v5 ctcae5:C144020 3-5 units below LLN; for follow-up, a decrease of 3-5 units (ml/min/mm Hg) below the baseline value; asymptomatic and intervention not indicated 3-5 units below LLN; for follow-up, a decrease of 3-5 units (ml/min/mm Hg) below the baseline value; asymptomatic and intervention not indicated Grade 1 Carbon Monoxide Diffusing Capacity Decreased, CTCAE Grade 1 Carbon monoxide diffusing capacity decreased 10065906 C144020 Grade 1 Carbon monoxide diffusing capacity decreased Grade 1 Carbon monoxide diffusing capacity decreased 3-5 units below LLN; for follow-up, a decrease of 3-5 units (ml/min/mm Hg) below the baseline value; asymptomatic and intervention not indicated NCI 3-5 units below LLN; for follow-up, a decrease of 3-5 units (ml/min/mm Hg) below the baseline value; asymptomatic and intervention not indicated CTCAE_v5 Grade 1 Carbon Monoxide Diffusing Capacity Decreased, CTCAE PT NCI Grade 1 Carbon monoxide diffusing capacity decreased PT CTCAE_v5 ctcae5:C144021 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Cardiac Disorders - Other, Specify, CTCAE Grade 1 Cardiac disorders - Other, specify 10007541 C144021 Grade 1 Cardiac disorders - Other, specify Grade 1 Cardiac disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Cardiac Disorders - Other, Specify, CTCAE PT NCI Grade 1 Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C144022 Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer Grade 1 Cardiac Troponin I Increased, CTCAE Grade 1 Cardiac troponin I increased 10007612 C144022 Grade 1 Cardiac troponin I increased Grade 1 Cardiac troponin I increased Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer NCI Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer CTCAE_v5 Grade 1 Cardiac Troponin I Increased, CTCAE PT NCI Grade 1 Cardiac troponin I increased PT CTCAE_v5 ctcae5:C144023 Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer Grade 1 Cardiac Troponin T Increased, CTCAE Grade 1 Cardiac troponin T increased 10007613 C144023 Grade 1 Cardiac troponin T increased Grade 1 Cardiac troponin T increased Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer NCI Levels above the upper limit of normal and below the level of myocardial infarction as defined by the manufacturer CTCAE_v5 Grade 1 Cardiac Troponin T Increased, CTCAE PT NCI Grade 1 Cardiac troponin T increased PT CTCAE_v5 ctcae5:C144024 <LLN-500/mm3; <LLN-0.5 x 10e9/L <LLN-500/mm3; <LLN-0.5 x 10e9/L Grade 1 CD4 Lymphocytes Decreased, CTCAE Grade 1 CD4 lymphocytes decreased 10007839 C144024 Grade 1 CD4 lymphocytes decreased Grade 1 CD4 lymphocytes decreased <LLN-500/mm3; <LLN-0.5 x 10e9/L NCI <LLN-500/mm3; <LLN-0.5 x 10e9/L CTCAE_v5 Grade 1 CD4 Lymphocytes Decreased, CTCAE PT NCI Grade 1 CD4 lymphocytes decreased PT CTCAE_v5 ctcae5:C144025 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Cecal Hemorrhage, CTCAE Grade 1 Cecal hemorrhage 10065747 C144025 Grade 1 Cecal hemorrhage Grade 1 Cecal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Cecal Hemorrhage, CTCAE PT NCI Grade 1 Cecal hemorrhage PT CTCAE_v5 ctcae5:C144026 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Central Nervous System Necrosis, CTCAE Grade 1 Central nervous system necrosis 10065784 C144026 Grade 1 Central nervous system necrosis Grade 1 Central nervous system necrosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Central Nervous System Necrosis, CTCAE PT NCI Grade 1 Central nervous system necrosis PT CTCAE_v5 ctcae5:C144027 Post-craniotomy: asymptomatic; Post-lumbar puncture: transient headache; postural care indicated Post-craniotomy: asymptomatic; Post-lumbar puncture: transient headache; postural care indicated Grade 1 Cerebrospinal Fluid Leakage, CTCAE Grade 1 Cerebrospinal fluid leakage 10008164 C144027 Grade 1 Cerebrospinal fluid leakage Grade 1 Cerebrospinal fluid leakage Post-craniotomy: asymptomatic; Post-lumbar puncture: transient headache; postural care indicated NCI Post-craniotomy: asymptomatic; Post-lumbar puncture: transient headache; postural care indicated CTCAE_v5 Grade 1 Cerebrospinal Fluid Leakage, CTCAE PT NCI Grade 1 Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C144028 Mild pain Mild pain Grade 1 Chest Pain - Cardiac, CTCAE Grade 1 Chest pain - cardiac 10008481 C144028 Grade 1 Chest pain - cardiac Grade 1 Chest pain - cardiac Mild pain NCI Mild pain CTCAE_v5 Grade 1 Chest Pain - Cardiac, CTCAE PT NCI Grade 1 Chest pain - cardiac PT CTCAE_v5 ctcae5:C144029 Mild sensation of cold; shivering; chattering of teeth Mild sensation of cold; shivering; chattering of teeth Grade 1 Chills Grade 1 Chills, CTCAE 10008531 C144029 Grade 1 Chills Grade 1 Chills Mild sensation of cold; shivering; chattering of teeth NCI Mild sensation of cold; shivering; chattering of teeth CTCAE_v5 Grade 1 Chills PT CTCAE_v5 Grade 1 Chills, CTCAE PT NCI ctcae5:C144030 >ULN-300 mg/dL; >ULN-7.75 mmol/L >ULN-300 mg/dL; >ULN-7.75 mmol/L Grade 1 Cholesterol High, CTCAE Grade 1 Cholesterol high 10008661 C144030 Grade 1 Cholesterol high Grade 1 Cholesterol high >ULN-300 mg/dL; >ULN-7.75 mmol/L NCI >ULN-300 mg/dL; >ULN-7.75 mmol/L CTCAE_v5 Grade 1 Cholesterol High, CTCAE PT NCI Grade 1 Cholesterol high PT CTCAE_v5 ctcae5:C144031 eGFR (estimated Glomerular Filtration Rate) or CrCl (creatinine clearance) <LLN-60 ml/min/1.73 m2 or proteinuria 2+ present; urine protein/creatinine >0.5 eGFR (estimated Glomerular Filtration Rate) or CrCl (creatinine clearance) <LLN-60 ml/min/1.73 m2 or proteinuria 2+ present; urine protein/creatinine >0.5 Grade 1 Chronic Kidney Disease, CTCAE Grade 1 Chronic kidney disease 10064848 C144031 Grade 1 Chronic kidney disease Grade 1 Chronic kidney disease eGFR (estimated Glomerular Filtration Rate) or CrCl (creatinine clearance) <LLN-60 ml/min/1.73 m2 or proteinuria 2+ present; urine protein/creatinine >0.5 NCI eGFR (estimated Glomerular Filtration Rate) or CrCl (creatinine clearance) <LLN-60 ml/min/1.73 m2 or proteinuria 2+ present; urine protein/creatinine >0.5 CTCAE_v5 Grade 1 Chronic Kidney Disease, CTCAE PT NCI Grade 1 Chronic kidney disease PT CTCAE_v5 ctcae5:C144032 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Chylous Ascites, CTCAE Grade 1 Chylous ascites 10009167 C144032 Grade 1 Chylous ascites Grade 1 Chylous ascites Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Chylous Ascites, CTCAE PT NCI Grade 1 Chylous ascites PT CTCAE_v5 ctcae5:C144033 Asymptomatic Asymptomatic Grade 1 Colonic Fistula, CTCAE Grade 1 Colonic fistula 10009995 C144033 Grade 1 Colonic fistula Grade 1 Colonic fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Colonic Fistula, CTCAE PT NCI Grade 1 Colonic fistula PT CTCAE_v5 ctcae5:C144034 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Colonic Hemorrhage, CTCAE Grade 1 Colonic hemorrhage 10009998 C144034 Grade 1 Colonic hemorrhage Grade 1 Colonic hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Colonic Hemorrhage, CTCAE PT NCI Grade 1 Colonic hemorrhage PT CTCAE_v5 ctcae5:C144035 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Colonic Obstruction, CTCAE Grade 1 Colonic obstruction 10010000 C144035 Grade 1 Colonic obstruction Grade 1 Colonic obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Colonic Obstruction, CTCAE PT NCI Grade 1 Colonic obstruction PT CTCAE_v5 ctcae5:C144036 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Colonic Stenosis, CTCAE Grade 1 Colonic stenosis 10010004 C144036 Grade 1 Colonic stenosis Grade 1 Colonic stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Colonic Stenosis, CTCAE PT NCI Grade 1 Colonic stenosis PT CTCAE_v5 ctcae5:C144037 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Colonic Ulcer, CTCAE Grade 1 Colonic ulcer 10010006 C144037 Grade 1 Colonic ulcer Grade 1 Colonic ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Colonic Ulcer, CTCAE PT NCI Grade 1 Colonic ulcer PT CTCAE_v5 ctcae5:C144038 Mild inattention or decreased level of concentration Mild inattention or decreased level of concentration Grade 1 Concentration Impairment, CTCAE Grade 1 Concentration impairment 10010250 C144038 Grade 1 Concentration impairment Grade 1 Concentration impairment Mild inattention or decreased level of concentration NCI Mild inattention or decreased level of concentration CTCAE_v5 Grade 1 Concentration Impairment, CTCAE PT NCI Grade 1 Concentration impairment PT CTCAE_v5 ctcae5:C144039 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Conduction Disorder, CTCAE Grade 1 Conduction disorder 10010276 C144039 Grade 1 Conduction disorder Grade 1 Conduction disorder Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Conduction Disorder, CTCAE PT NCI Grade 1 Conduction disorder PT CTCAE_v5 ctcae5:C144040 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Grade 1 Congenital, familial and genetic disorders - Other, specify 10010331 C144040 Grade 1 Congenital, familial and genetic disorders - Other, specify Grade 1 Congenital, familial and genetic disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Grade 1 Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C144041 Asymptomatic or mild symptoms; intervention not indicated Asymptomatic or mild symptoms; intervention not indicated Grade 1 Conjunctivitis Grade 1 Conjunctivitis, CTCAE 10010741 C144041 Grade 1 Conjunctivitis Grade 1 Conjunctivitis Asymptomatic or mild symptoms; intervention not indicated NCI Asymptomatic or mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Conjunctivitis PT CTCAE_v5 Grade 1 Conjunctivitis, CTCAE PT NCI ctcae5:C144042 >ULN-2.5 x ULN >ULN-2.5 x ULN Grade 1 CPK Increased, CTCAE Grade 1 CPK increased 10011268 C144042 Grade 1 CPK increased Grade 1 CPK increased >ULN-2.5 x ULN NCI >ULN-2.5 x ULN CTCAE_v5 Grade 1 CPK Increased, CTCAE PT NCI Grade 1 CPK increased PT CTCAE_v5 ctcae5:C144043 >ULN-1.5 x ULN >ULN-1.5 x ULN Grade 1 Creatinine Increased, CTCAE Grade 1 Creatinine increased 10011368 C144043 Grade 1 Creatinine increased Grade 1 Creatinine increased >ULN-1.5 x ULN NCI >ULN-1.5 x ULN CTCAE_v5 Grade 1 Creatinine Increased, CTCAE PT NCI Grade 1 Creatinine increased PT CTCAE_v5 ctcae5:C144044 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Cushingoid Grade 1 Cushingoid, CTCAE 10011655 C144044 Grade 1 Cushingoid Grade 1 Cushingoid Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Cushingoid PT CTCAE_v5 Grade 1 Cushingoid, CTCAE PT NCI ctcae5:C144045 Microscopic hematuria; minimal increase in frequency, urgency, dysuria, or nocturia; new onset of incontinence Microscopic hematuria; minimal increase in frequency, urgency, dysuria, or nocturia; new onset of incontinence Grade 1 Cystitis Noninfective, CTCAE Grade 1 Cystitis noninfective 10063057 C144045 Grade 1 Cystitis noninfective Grade 1 Cystitis noninfective Microscopic hematuria; minimal increase in frequency, urgency, dysuria, or nocturia; new onset of incontinence NCI Microscopic hematuria; minimal increase in frequency, urgency, dysuria, or nocturia; new onset of incontinence CTCAE_v5 Grade 1 Cystitis Noninfective, CTCAE PT NCI Grade 1 Cystitis noninfective PT CTCAE_v5 ctcae5:C144046 Fever with or without constitutional symptoms Fever with or without constitutional symptoms Grade 1 Cytokine Release Syndrome, CTCAE Grade 1 Cytokine release syndrome 10052015 C144046 Grade 1 Cytokine release syndrome Grade 1 Cytokine release syndrome Fever with or without constitutional symptoms NCI Fever with or without constitutional symptoms CTCAE_v5 Grade 1 Cytokine Release Syndrome, CTCAE PT NCI Grade 1 Cytokine release syndrome PT CTCAE_v5 ctcae5:C144047 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Cytomegalovirus Infection Reactivation, CTCAE Grade 1 Cytomegalovirus infection reactivation 10058666 C144047 Grade 1 Cytomegalovirus infection reactivation Grade 1 Cytomegalovirus infection reactivation Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Grade 1 Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C144048 Delay in achieving orgasm not adversely affecting relationship Delay in achieving orgasm not adversely affecting relationship Grade 1 Delayed Orgasm, CTCAE Grade 1 Delayed orgasm 10057066 C144048 Grade 1 Delayed orgasm Grade 1 Delayed orgasm Delay in achieving orgasm not adversely affecting relationship NCI Delay in achieving orgasm not adversely affecting relationship CTCAE_v5 Grade 1 Delayed Orgasm, CTCAE PT NCI Grade 1 Delayed orgasm PT CTCAE_v5 ctcae5:C144049 Mild acute confusional state Mild acute confusional state Grade 1 Delirium Grade 1 Delirium, CTCAE 10012218 C144049 Grade 1 Delirium Grade 1 Delirium Mild acute confusional state NCI Mild acute confusional state CTCAE_v5 Grade 1 Delirium PT CTCAE_v5 Grade 1 Delirium, CTCAE PT NCI ctcae5:C144050 One or more dental caries, not involving the root One or more dental caries, not involving the root Grade 1 Dental Caries, CTCAE Grade 1 Dental caries 10012318 C144050 Grade 1 Dental caries Grade 1 Dental caries One or more dental caries, not involving the root NCI One or more dental caries, not involving the root CTCAE_v5 Grade 1 Dental Caries, CTCAE PT NCI Grade 1 Dental caries PT CTCAE_v5 ctcae5:C144051 Decreased level of alertness Decreased level of alertness Grade 1 Depressed Level of Consciousness, CTCAE Grade 1 Depressed level of consciousness 10012373 C144051 Grade 1 Depressed level of consciousness Grade 1 Depressed level of consciousness Decreased level of alertness NCI Decreased level of alertness CTCAE_v5 Grade 1 Depressed Level of Consciousness, CTCAE PT NCI Grade 1 Depressed level of consciousness PT CTCAE_v5 ctcae5:C144052 Faint erythema or dry desquamation Faint erythema or dry desquamation Grade 1 Dermatitis Radiation, CTCAE Grade 1 Dermatitis radiation 10061103 C144052 Grade 1 Dermatitis radiation Grade 1 Dermatitis radiation Faint erythema or dry desquamation NCI Faint erythema or dry desquamation CTCAE_v5 Grade 1 Dermatitis Radiation, CTCAE PT NCI Grade 1 Dermatitis radiation PT CTCAE_v5 ctcae5:C144053 Asymptomatic; clinical or diagnostic observations only; symptoms relieved by lubricants Asymptomatic; clinical or diagnostic observations only; symptoms relieved by lubricants Grade 1 Dry Eye, CTCAE Grade 1 Dry eye 10013774 C144053 Grade 1 Dry eye Grade 1 Dry eye Asymptomatic; clinical or diagnostic observations only; symptoms relieved by lubricants NCI Asymptomatic; clinical or diagnostic observations only; symptoms relieved by lubricants CTCAE_v5 Grade 1 Dry Eye, CTCAE PT NCI Grade 1 Dry eye PT CTCAE_v5 ctcae5:C144054 Symptomatic (e.g., dry or thick saliva) without significant dietary alteration; unstimulated saliva flow >0.2 ml/min Symptomatic (e.g., dry or thick saliva) without significant dietary alteration; unstimulated saliva flow >0.2 ml/min Grade 1 Dry Mouth, CTCAE Grade 1 Dry mouth 10013781 C144054 Grade 1 Dry mouth Grade 1 Dry mouth Symptomatic (e.g., dry or thick saliva) without significant dietary alteration; unstimulated saliva flow >0.2 ml/min NCI Symptomatic (e.g., dry or thick saliva) without significant dietary alteration; unstimulated saliva flow >0.2 ml/min CTCAE_v5 Grade 1 Dry Mouth, CTCAE PT NCI Grade 1 Dry mouth PT CTCAE_v5 ctcae5:C144056 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Duodenal Hemorrhage, CTCAE Grade 1 Duodenal hemorrhage 10055242 C144056 Grade 1 Duodenal hemorrhage Grade 1 Duodenal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Duodenal Hemorrhage, CTCAE PT NCI Grade 1 Duodenal hemorrhage PT CTCAE_v5 ctcae5:C144057 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Duodenal Obstruction, CTCAE Grade 1 Duodenal obstruction 10013830 C144057 Grade 1 Duodenal obstruction Grade 1 Duodenal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Duodenal Obstruction, CTCAE PT NCI Grade 1 Duodenal obstruction PT CTCAE_v5 ctcae5:C144058 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Duodenal Stenosis, CTCAE Grade 1 Duodenal stenosis 10050094 C144058 Grade 1 Duodenal stenosis Grade 1 Duodenal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Duodenal Stenosis, CTCAE PT NCI Grade 1 Duodenal stenosis PT CTCAE_v5 ctcae5:C144059 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Duodenal Ulcer, CTCAE Grade 1 Duodenal ulcer 10013836 C144059 Grade 1 Duodenal ulcer Grade 1 Duodenal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Duodenal Ulcer, CTCAE PT NCI Grade 1 Duodenal ulcer PT CTCAE_v5 ctcae5:C144060 Mild slurred speech Mild slurred speech Grade 1 Dysarthria Grade 1 Dysarthria, CTCAE 10013887 C144060 Grade 1 Dysarthria Grade 1 Dysarthria Mild slurred speech NCI Mild slurred speech CTCAE_v5 Grade 1 Dysarthria PT CTCAE_v5 Grade 1 Dysarthria, CTCAE PT NCI ctcae5:C144061 Mild sensory alteration Mild sensory alteration Grade 1 Dysesthesia Grade 1 Dysesthesia, CTCAE 10062872 C144061 Grade 1 Dysesthesia Grade 1 Dysesthesia Mild sensory alteration NCI Mild sensory alteration CTCAE_v5 Grade 1 Dysesthesia PT CTCAE_v5 Grade 1 Dysesthesia, CTCAE PT NCI ctcae5:C144062 Altered taste but no change in diet Altered taste but no change in diet Grade 1 Dysgeusia Grade 1 Dysgeusia, CTCAE 10013911 C144062 Grade 1 Dysgeusia Grade 1 Dysgeusia Altered taste but no change in diet NCI Altered taste but no change in diet CTCAE_v5 Grade 1 Dysgeusia PT CTCAE_v5 Grade 1 Dysgeusia, CTCAE PT NCI ctcae5:C144063 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Dysmenorrhea Grade 1 Dysmenorrhea, CTCAE 10013934 C144063 Grade 1 Dysmenorrhea Grade 1 Dysmenorrhea Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Dysmenorrhea PT CTCAE_v5 Grade 1 Dysmenorrhea, CTCAE PT NCI ctcae5:C144064 Mild discomfort or pain associated with vaginal penetration; discomfort relieved with use of vaginal lubricants or estrogen Mild discomfort or pain associated with vaginal penetration; discomfort relieved with use of vaginal lubricants or estrogen Grade 1 Dyspareunia Grade 1 Dyspareunia, CTCAE 10013941 C144064 Grade 1 Dyspareunia Grade 1 Dyspareunia Mild discomfort or pain associated with vaginal penetration; discomfort relieved with use of vaginal lubricants or estrogen NCI Mild discomfort or pain associated with vaginal penetration; discomfort relieved with use of vaginal lubricants or estrogen CTCAE_v5 Grade 1 Dyspareunia PT CTCAE_v5 Grade 1 Dyspareunia, CTCAE PT NCI ctcae5:C144065 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Dyspepsia Grade 1 Dyspepsia, CTCAE 10013946 C144065 Grade 1 Dyspepsia Grade 1 Dyspepsia Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Dyspepsia PT CTCAE_v5 Grade 1 Dyspepsia, CTCAE PT NCI ctcae5:C144066 Awareness of receptive or expressive characteristics; not impairing ability to communicate Awareness of receptive or expressive characteristics; not impairing ability to communicate Grade 1 Dysphasia Grade 1 Dysphasia, CTCAE 10013951 C144066 Grade 1 Dysphasia Grade 1 Dysphasia Awareness of receptive or expressive characteristics; not impairing ability to communicate NCI Awareness of receptive or expressive characteristics; not impairing ability to communicate CTCAE_v5 Grade 1 Dysphasia PT CTCAE_v5 Grade 1 Dysphasia, CTCAE PT NCI ctcae5:C144067 Present Present Grade 1 Dysuria Grade 1 Dysuria, CTCAE 10013990 C144067 Grade 1 Dysuria Grade 1 Dysuria Present NCI Present CTCAE_v5 Grade 1 Dysuria PT CTCAE_v5 Grade 1 Dysuria, CTCAE PT NCI ctcae5:C144068 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Ear and Labyrinth Disorders - Other, Specify, CTCAE Grade 1 Ear and labyrinth disorders - Other, specify 10013993 C144068 Grade 1 Ear and labyrinth disorders - Other, specify Grade 1 Ear and labyrinth disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Grade 1 Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C144069 Mild pain Mild pain Grade 1 Ear Pain, CTCAE Grade 1 Ear pain 10014020 C144069 Grade 1 Ear pain Grade 1 Ear pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Ear Pain, CTCAE PT NCI Grade 1 Ear pain PT CTCAE_v5 ctcae5:C144070 Asymptomatic or mild symptoms; additional medical intervention over baseline not indicated Asymptomatic or mild symptoms; additional medical intervention over baseline not indicated Grade 1 Eczema Grade 1 Eczema, CTCAE 10014184 C144070 Grade 1 Eczema Grade 1 Eczema Asymptomatic or mild symptoms; additional medical intervention over baseline not indicated NCI Asymptomatic or mild symptoms; additional medical intervention over baseline not indicated CTCAE_v5 Grade 1 Eczema PT CTCAE_v5 Grade 1 Eczema, CTCAE PT NCI ctcae5:C144071 Localized facial edema Localized facial edema Grade 1 Edema Face, CTCAE Grade 1 Edema face 10014222 C144071 Grade 1 Edema face Grade 1 Edema face Localized facial edema NCI Localized facial edema CTCAE_v5 Grade 1 Edema Face, CTCAE PT NCI Grade 1 Edema face PT CTCAE_v5 ctcae5:C144072 5-10% inter-limb discrepancy in volume or circumference at point of greatest visible difference; swelling or obscuration of anatomic architecture on close inspection 5-10% inter-limb discrepancy in volume or circumference at point of greatest visible difference; swelling or obscuration of anatomic architecture on close inspection Grade 1 Edema Limbs, CTCAE Grade 1 Edema limbs 10050068 C144072 Grade 1 Edema limbs Grade 1 Edema limbs 5-10% inter-limb discrepancy in volume or circumference at point of greatest visible difference; swelling or obscuration of anatomic architecture on close inspection NCI 5-10% inter-limb discrepancy in volume or circumference at point of greatest visible difference; swelling or obscuration of anatomic architecture on close inspection CTCAE_v5 Grade 1 Edema Limbs, CTCAE PT NCI Grade 1 Edema limbs PT CTCAE_v5 ctcae5:C144073 Swelling or obscuration of anatomic architecture on close inspection Swelling or obscuration of anatomic architecture on close inspection Grade 1 Edema Trunk, CTCAE Grade 1 Edema trunk 10058720 C144073 Grade 1 Edema trunk Grade 1 Edema trunk Swelling or obscuration of anatomic architecture on close inspection NCI Swelling or obscuration of anatomic architecture on close inspection CTCAE_v5 Grade 1 Edema Trunk, CTCAE PT NCI Grade 1 Edema trunk PT CTCAE_v5 ctcae5:C144074 Diminished ejaculation Diminished ejaculation Grade 1 Ejaculation Disorder, CTCAE Grade 1 Ejaculation disorder 10014326 C144074 Grade 1 Ejaculation disorder Grade 1 Ejaculation disorder Diminished ejaculation NCI Diminished ejaculation CTCAE_v5 Grade 1 Ejaculation Disorder, CTCAE PT NCI Grade 1 Ejaculation disorder PT CTCAE_v5 ctcae5:C144075 Average QTc 450-480 ms Average QTc 450-480 ms Grade 1 Electrocardiogram QT Corrected Interval Prolonged, CTCAE Grade 1 Electrocardiogram QT corrected interval prolonged 10014383 C144075 Grade 1 Electrocardiogram QT corrected interval prolonged Grade 1 Electrocardiogram QT corrected interval prolonged Average QTc 450-480 ms NCI Average QTc 450-480 ms CTCAE_v5 Grade 1 Electrocardiogram QT Corrected Interval Prolonged, CTCAE PT NCI Grade 1 Electrocardiogram QT corrected interval prolonged PT CTCAE_v5 ctcae5:C144076 T wave flattening T wave flattening Grade 1 Electrocardiogram T Wave Abnormal, CTCAE Grade 1 Electrocardiogram T wave abnormal 10050380 C144076 Grade 1 Electrocardiogram T wave abnormal Grade 1 Electrocardiogram T wave abnormal T wave flattening NCI T wave flattening CTCAE_v5 Grade 1 Electrocardiogram T Wave Abnormal, CTCAE PT NCI Grade 1 Electrocardiogram T wave abnormal PT CTCAE_v5 ctcae5:C144077 Mild symptoms Mild symptoms Grade 1 Encephalopathy Grade 1 Encephalopathy, CTCAE 10014625 C144077 Grade 1 Encephalopathy Grade 1 Encephalopathy Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Encephalopathy PT CTCAE_v5 Grade 1 Encephalopathy, CTCAE PT NCI ctcae5:C144078 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Endocrine Disorders - Other, Specify, CTCAE Grade 1 Endocrine disorders - Other, specify 10014698 C144078 Grade 1 Endocrine disorders - Other, specify Grade 1 Endocrine disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Endocrine Disorders - Other, Specify, CTCAE PT NCI Grade 1 Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C144079 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Enterocolitis Grade 1 Enterocolitis, CTCAE 10014893 C144079 Grade 1 Enterocolitis Grade 1 Enterocolitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Enterocolitis PT CTCAE_v5 Grade 1 Enterocolitis, CTCAE PT NCI ctcae5:C144080 Asymptomatic Asymptomatic Grade 1 Enterovesical Fistula, CTCAE Grade 1 Enterovesical fistula 10062570 C144080 Grade 1 Enterovesical fistula Grade 1 Enterovesical fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Enterovesical Fistula, CTCAE PT NCI Grade 1 Enterovesical fistula PT CTCAE_v5 ctcae5:C144081 >ULN and >Baseline >ULN and >Baseline Grade 1 Eosinophilia Grade 1 Eosinophilia, CTCAE 10014950 C144081 Grade 1 Eosinophilia Grade 1 Eosinophilia >ULN and >Baseline NCI >ULN and >Baseline CTCAE_v5 Grade 1 Eosinophilia PT CTCAE_v5 Grade 1 Eosinophilia, CTCAE PT NCI ctcae5:C144082 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Epistaxis Grade 1 Epistaxis, CTCAE 10015090 C144082 Grade 1 Epistaxis Grade 1 Epistaxis Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Epistaxis PT CTCAE_v5 Grade 1 Epistaxis, CTCAE PT NCI ctcae5:C144083 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Epstein-Barr Virus Infection Reactivation, CTCAE Grade 1 Epstein-Barr virus infection reactivation 10015109 C144083 Grade 1 Epstein-Barr virus infection reactivation Grade 1 Epstein-Barr virus infection reactivation Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Grade 1 Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C144084 Target lesions covering <10% BSA and not associated with skin tenderness Target lesions covering <10% BSA and not associated with skin tenderness Grade 1 Erythema Multiforme, CTCAE Grade 1 Erythema multiforme 10015218 C144084 Grade 1 Erythema multiforme Grade 1 Erythema multiforme Target lesions covering <10% BSA and not associated with skin tenderness NCI Target lesions covering <10% BSA and not associated with skin tenderness CTCAE_v5 Grade 1 Erythema Multiforme, CTCAE PT NCI Grade 1 Erythema multiforme PT CTCAE_v5 ctcae5:C144085 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Esophageal Anastomotic Leak, CTCAE Grade 1 Esophageal anastomotic leak 10065961 C144085 Grade 1 Esophageal anastomotic leak Grade 1 Esophageal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Esophageal Anastomotic Leak, CTCAE PT NCI Grade 1 Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C144087 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Esophageal Hemorrhage, CTCAE Grade 1 Esophageal hemorrhage 10015384 C144087 Grade 1 Esophageal hemorrhage Grade 1 Esophageal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Esophageal Hemorrhage, CTCAE PT NCI Grade 1 Esophageal hemorrhage PT CTCAE_v5 ctcae5:C144088 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Esophageal Obstruction, CTCAE Grade 1 Esophageal obstruction 10015387 C144088 Grade 1 Esophageal obstruction Grade 1 Esophageal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Esophageal Obstruction, CTCAE PT NCI Grade 1 Esophageal obstruction PT CTCAE_v5 ctcae5:C144089 Mild pain Mild pain Grade 1 Esophageal Pain, CTCAE Grade 1 Esophageal pain 10015388 C144089 Grade 1 Esophageal pain Grade 1 Esophageal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Esophageal Pain, CTCAE PT NCI Grade 1 Esophageal pain PT CTCAE_v5 ctcae5:C144090 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Esophageal Stenosis, CTCAE Grade 1 Esophageal stenosis 10015448 C144090 Grade 1 Esophageal stenosis Grade 1 Esophageal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Esophageal Stenosis, CTCAE PT NCI Grade 1 Esophageal stenosis PT CTCAE_v5 ctcae5:C144091 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Esophageal Ulcer, CTCAE Grade 1 Esophageal ulcer 10015451 C144091 Grade 1 Esophageal ulcer Grade 1 Esophageal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Esophageal Ulcer, CTCAE PT NCI Grade 1 Esophageal ulcer PT CTCAE_v5 ctcae5:C144092 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Extraocular Muscle Paresis, CTCAE Grade 1 Extraocular muscle paresis 10015829 C144092 Grade 1 Extraocular muscle paresis Grade 1 Extraocular muscle paresis Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Extraocular Muscle Paresis, CTCAE PT NCI Grade 1 Extraocular muscle paresis PT CTCAE_v5 ctcae5:C144093 Mild involuntary movements Mild involuntary movements Grade 1 Extrapyramidal Disorder, CTCAE Grade 1 Extrapyramidal disorder 10015832 C144093 Grade 1 Extrapyramidal disorder Grade 1 Extrapyramidal disorder Mild involuntary movements NCI Mild involuntary movements CTCAE_v5 Grade 1 Extrapyramidal Disorder, CTCAE PT NCI Grade 1 Extrapyramidal disorder PT CTCAE_v5 ctcae5:C144094 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated; no change in vision Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated; no change in vision Grade 1 Eye Disorders - Other, Specify, CTCAE Grade 1 Eye disorders - Other, specify 10015919 C144094 Grade 1 Eye disorders - Other, specify Grade 1 Eye disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated; no change in vision NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated; no change in vision CTCAE_v5 Grade 1 Eye Disorders - Other, Specify, CTCAE PT NCI Grade 1 Eye disorders - Other, specify PT CTCAE_v5 ctcae5:C144095 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Eyelid Function Disorder, CTCAE Grade 1 Eyelid function disorder 10061145 C144095 Grade 1 Eyelid function disorder Grade 1 Eyelid function disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Eyelid Function Disorder, CTCAE PT NCI Grade 1 Eyelid function disorder PT CTCAE_v5 ctcae5:C144096 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Facial Muscle Weakness, CTCAE Grade 1 Facial muscle weakness 10051272 C144096 Grade 1 Facial muscle weakness Grade 1 Facial muscle weakness Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Facial Muscle Weakness, CTCAE PT NCI Grade 1 Facial muscle weakness PT CTCAE_v5 ctcae5:C144097 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Facial Nerve Disorder, CTCAE Grade 1 Facial nerve disorder 10061457 C144097 Grade 1 Facial nerve disorder Grade 1 Facial nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Facial Nerve Disorder, CTCAE PT NCI Grade 1 Facial nerve disorder PT CTCAE_v5 ctcae5:C144098 Mild pain Mild pain Grade 1 Facial Pain, CTCAE Grade 1 Facial pain 10016059 C144098 Grade 1 Facial pain Grade 1 Facial pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Facial Pain, CTCAE PT NCI Grade 1 Facial pain PT CTCAE_v5 ctcae5:C144099 Minor with no resultant injuries; intervention not indicated Minor with no resultant injuries; intervention not indicated Grade 1 Fall Grade 1 Fall, CTCAE 10016173 C144099 Grade 1 Fall Grade 1 Fall Minor with no resultant injuries; intervention not indicated NCI Minor with no resultant injuries; intervention not indicated CTCAE_v5 Grade 1 Fall PT CTCAE_v5 Grade 1 Fall, CTCAE PT NCI ctcae5:C144100 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Fallopian Tube Anastomotic Leak, CTCAE Grade 1 Fallopian tube anastomotic leak 10065788 C144100 Grade 1 Fallopian tube anastomotic leak Grade 1 Fallopian tube anastomotic leak Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Grade 1 Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C144101 Covering <10% BSA and asymptomatic Covering <10% BSA and asymptomatic Grade 1 Fat Atrophy, CTCAE Grade 1 Fat atrophy 10016241 C144101 Grade 1 Fat atrophy Grade 1 Fat atrophy Covering <10% BSA and asymptomatic NCI Covering <10% BSA and asymptomatic CTCAE_v5 Grade 1 Fat Atrophy, CTCAE PT NCI Grade 1 Fat atrophy PT CTCAE_v5 ctcae5:C144102 Occasional use of pads required Occasional use of pads required Grade 1 Fecal Incontinence, CTCAE Grade 1 Fecal incontinence 10016296 C144102 Grade 1 Fecal incontinence Grade 1 Fecal incontinence Occasional use of pads required NCI Occasional use of pads required CTCAE_v5 Grade 1 Fecal Incontinence, CTCAE PT NCI Grade 1 Fecal incontinence PT CTCAE_v5 ctcae5:C144103 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Feminization Acquired, CTCAE Grade 1 Feminization acquired 10054382 C144103 Grade 1 Feminization acquired Grade 1 Feminization acquired Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Feminization Acquired, CTCAE PT NCI Grade 1 Feminization acquired PT CTCAE_v5 ctcae5:C144104 38.0-39.0 degrees C (100.4-102.2 degrees F) 38.0-39.0 degrees C (100.4-102.2 degrees F) Grade 1 Fever Grade 1 Fever, CTCAE 10016558 C144104 Grade 1 Fever Grade 1 Fever 38.0-39.0 degrees C (100.4-102.2 degrees F) NCI 38.0-39.0 degrees C (100.4-102.2 degrees F) CTCAE_v5 Grade 1 Fever PT CTCAE_v5 Grade 1 Fever, CTCAE PT NCI ctcae5:C144105 <1.0-0.75 x LLN; if abnormal, <25% decrease from baseline <1.0-0.75 x LLN; if abnormal, <25% decrease from baseline Grade 1 Fibrinogen Decreased, CTCAE Grade 1 Fibrinogen decreased 10016596 C144105 Grade 1 Fibrinogen decreased Grade 1 Fibrinogen decreased <1.0-0.75 x LLN; if abnormal, <25% decrease from baseline NCI <1.0-0.75 x LLN; if abnormal, <25% decrease from baseline CTCAE_v5 Grade 1 Fibrinogen Decreased, CTCAE PT NCI Grade 1 Fibrinogen decreased PT CTCAE_v5 ctcae5:C144106 Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Grade 1 Fibrosis Deep Connective Tissue, CTCAE Grade 1 Fibrosis deep connective tissue 10065799 C144106 Grade 1 Fibrosis deep connective tissue Grade 1 Fibrosis deep connective tissue Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) NCI Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) CTCAE_v5 Grade 1 Fibrosis Deep Connective Tissue, CTCAE PT NCI Grade 1 Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C144107 Mild pain Mild pain Grade 1 Flank Pain, CTCAE Grade 1 Flank pain 10016750 C144107 Grade 1 Flank pain Grade 1 Flank pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Flank Pain, CTCAE PT NCI Grade 1 Flank pain PT CTCAE_v5 ctcae5:C144108 Symptomatic but not limiting ADL Symptomatic but not limiting ADL Grade 1 Flashing Lights, CTCAE Grade 1 Flashing lights 10016757 C144108 Grade 1 Flashing lights Grade 1 Flashing lights Symptomatic but not limiting ADL NCI Symptomatic but not limiting ADL CTCAE_v5 Grade 1 Flashing Lights, CTCAE PT NCI Grade 1 Flashing lights PT CTCAE_v5 ctcae5:C144109 Symptomatic but not limiting ADL Symptomatic but not limiting ADL Grade 1 Floaters Grade 1 Floaters, CTCAE 10016778 C144109 Grade 1 Floaters Grade 1 Floaters Symptomatic but not limiting ADL NCI Symptomatic but not limiting ADL CTCAE_v5 Grade 1 Floaters PT CTCAE_v5 Grade 1 Floaters, CTCAE PT NCI ctcae5:C144110 Mild flu-like symptoms present Mild flu-like symptoms present Grade 1 Flu Like Symptoms, CTCAE Grade 1 Flu like symptoms 10016791 C144110 Grade 1 Flu like symptoms Grade 1 Flu like symptoms Mild flu-like symptoms present NCI Mild flu-like symptoms present CTCAE_v5 Grade 1 Flu Like Symptoms, CTCAE PT NCI Grade 1 Flu like symptoms PT CTCAE_v5 ctcae5:C144111 Covering <10% of the body surface area; no intervention indicated Covering <10% of the body surface area; no intervention indicated Grade 1 Folliculitis Grade 1 Folliculitis, CTCAE 10016936 C144111 Grade 1 Folliculitis Grade 1 Folliculitis Covering <10% of the body surface area; no intervention indicated NCI Covering <10% of the body surface area; no intervention indicated CTCAE_v5 Grade 1 Folliculitis PT CTCAE_v5 Grade 1 Folliculitis, CTCAE PT NCI ctcae5:C144112 FEV1% (percentages of observed FEV1 and FVC related to their respective predicted values) 99-70% predicted FEV1% (percentages of observed FEV1 and FVC related to their respective predicted values) 99-70% predicted Grade 1 Forced Expiratory Volume Decreased, CTCAE Grade 1 Forced expiratory volume decreased 10016987 C144112 Grade 1 Forced expiratory volume decreased Grade 1 Forced expiratory volume decreased FEV1% (percentages of observed FEV1 and FVC related to their respective predicted values) 99-70% predicted NCI FEV1% (percentages of observed FEV1 and FVC related to their respective predicted values) 99-70% predicted CTCAE_v5 Grade 1 Forced Expiratory Volume Decreased, CTCAE PT NCI Grade 1 Forced expiratory volume decreased PT CTCAE_v5 ctcae5:C144113 Mild change in gait (e.g., wide-based, limping or hobbling) Mild change in gait (e.g., wide-based, limping or hobbling) Grade 1 Gait Disturbance, CTCAE Grade 1 Gait disturbance 10017577 C144113 Grade 1 Gait disturbance Grade 1 Gait disturbance Mild change in gait (e.g., wide-based, limping or hobbling) NCI Mild change in gait (e.g., wide-based, limping or hobbling) CTCAE_v5 Grade 1 Gait Disturbance, CTCAE PT NCI Grade 1 Gait disturbance PT CTCAE_v5 ctcae5:C144114 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Gastric Anastomotic Leak, CTCAE Grade 1 Gastric anastomotic leak 10065893 C144114 Grade 1 Gastric anastomotic leak Grade 1 Gastric anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Gastric Anastomotic Leak, CTCAE PT NCI Grade 1 Gastric anastomotic leak PT CTCAE_v5 ctcae5:C144115 Asymptomatic Asymptomatic Grade 1 Gastric Fistula, CTCAE Grade 1 Gastric fistula 10065713 C144115 Grade 1 Gastric fistula Grade 1 Gastric fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Gastric Fistula, CTCAE PT NCI Grade 1 Gastric fistula PT CTCAE_v5 ctcae5:C144116 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Gastric Hemorrhage, CTCAE Grade 1 Gastric hemorrhage 10017789 C144116 Grade 1 Gastric hemorrhage Grade 1 Gastric hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Gastric Hemorrhage, CTCAE PT NCI Grade 1 Gastric hemorrhage PT CTCAE_v5 ctcae5:C144117 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Gastric Stenosis, CTCAE Grade 1 Gastric stenosis 10061970 C144117 Grade 1 Gastric stenosis Grade 1 Gastric stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Gastric Stenosis, CTCAE PT NCI Grade 1 Gastric stenosis PT CTCAE_v5 ctcae5:C144118 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Gastric Ulcer, CTCAE Grade 1 Gastric ulcer 10017822 C144118 Grade 1 Gastric ulcer Grade 1 Gastric ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Gastric Ulcer, CTCAE PT NCI Grade 1 Gastric ulcer PT CTCAE_v5 ctcae5:C144119 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Gastroesophageal Reflux Disease, CTCAE Grade 1 Gastroesophageal reflux disease 10066874 C144119 Grade 1 Gastroesophageal reflux disease Grade 1 Gastroesophageal reflux disease Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Gastroesophageal Reflux Disease, CTCAE PT NCI Grade 1 Gastroesophageal reflux disease PT CTCAE_v5 ctcae5:C144120 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Gastrointestinal Anastomotic Leak, CTCAE Grade 1 Gastrointestinal anastomotic leak 10065879 C144120 Grade 1 Gastrointestinal anastomotic leak Grade 1 Gastrointestinal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Grade 1 Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C144121 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Gastrointestinal Disorders - Other, Specify, CTCAE Grade 1 Gastrointestinal disorders - Other, specify 10017947 C144121 Grade 1 Gastrointestinal disorders - Other, specify Grade 1 Gastrointestinal disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Grade 1 Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C144122 Asymptomatic Asymptomatic Grade 1 Gastrointestinal Fistula, CTCAE Grade 1 Gastrointestinal fistula 10017877 C144122 Grade 1 Gastrointestinal fistula Grade 1 Gastrointestinal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Gastrointestinal Fistula, CTCAE PT NCI Grade 1 Gastrointestinal fistula PT CTCAE_v5 ctcae5:C144123 Mild pain Mild pain Grade 1 Gastrointestinal Pain, CTCAE Grade 1 Gastrointestinal pain 10017999 C144123 Grade 1 Gastrointestinal pain Grade 1 Gastrointestinal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Gastrointestinal Pain, CTCAE PT NCI Grade 1 Gastrointestinal pain PT CTCAE_v5 ctcae5:C144124 Mild nausea, early satiety and bloating, able to maintain caloric intake on regular diet Mild nausea, early satiety and bloating, able to maintain caloric intake on regular diet Grade 1 Gastroparesis Grade 1 Gastroparesis, CTCAE 10018043 C144124 Grade 1 Gastroparesis Grade 1 Gastroparesis Mild nausea, early satiety and bloating, able to maintain caloric intake on regular diet NCI Mild nausea, early satiety and bloating, able to maintain caloric intake on regular diet CTCAE_v5 Grade 1 Gastroparesis PT CTCAE_v5 Grade 1 Gastroparesis, CTCAE PT NCI ctcae5:C144125 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 General Disorders and Administration Site Conditions - Other, Specify, CTCAE Grade 1 General disorders and administration site conditions - Other, specify 10018065 C144125 Grade 1 General disorders and administration site conditions - Other, specify Grade 1 General disorders and administration site conditions - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI Grade 1 General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C144126 Noted on exam; 1+ pitting edema Noted on exam; 1+ pitting edema Grade 1 Generalized Edema, CTCAE Grade 1 Generalized edema 10018112 C144126 Grade 1 Generalized edema Grade 1 Generalized edema Noted on exam; 1+ pitting edema NCI Noted on exam; 1+ pitting edema CTCAE_v5 Grade 1 Generalized Edema, CTCAE PT NCI Grade 1 Generalized edema PT CTCAE_v5 ctcae5:C144127 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Generalized Muscle Weakness, CTCAE Grade 1 Generalized muscle weakness 10062572 C144127 Grade 1 Generalized muscle weakness Grade 1 Generalized muscle weakness Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Generalized Muscle Weakness, CTCAE PT NCI Grade 1 Generalized muscle weakness PT CTCAE_v5 ctcae5:C144128 Mild swelling or obscuration of anatomic architecture on close inspection Mild swelling or obscuration of anatomic architecture on close inspection Grade 1 Genital Edema, CTCAE Grade 1 Genital edema 10018146 C144128 Grade 1 Genital edema Grade 1 Genital edema Mild swelling or obscuration of anatomic architecture on close inspection NCI Mild swelling or obscuration of anatomic architecture on close inspection CTCAE_v5 Grade 1 Genital Edema, CTCAE PT NCI Grade 1 Genital edema PT CTCAE_v5 ctcae5:C144129 >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal Grade 1 GGT Increased, CTCAE Grade 1 GGT increased 10056910 C144129 Grade 1 GGT increased Grade 1 GGT increased >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal NCI >ULN-2.5 x ULN if baseline was normal; 2.0-2.5 x baseline if baseline was abnormal CTCAE_v5 Grade 1 GGT Increased, CTCAE PT NCI Grade 1 GGT increased PT CTCAE_v5 ctcae5:C144130 Mild pain Mild pain Grade 1 Gingival Pain, CTCAE Grade 1 Gingival pain 10018286 C144130 Grade 1 Gingival pain Grade 1 Gingival pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Gingival Pain, CTCAE PT NCI Grade 1 Gingival pain PT CTCAE_v5 ctcae5:C144131 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Glossopharyngeal Nerve Disorder, CTCAE Grade 1 Glossopharyngeal nerve disorder 10061185 C144131 Grade 1 Glossopharyngeal nerve disorder Grade 1 Glossopharyngeal nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Grade 1 Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C144132 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Glucose Intolerance, CTCAE Grade 1 Glucose intolerance 10052426 C144132 Grade 1 Glucose intolerance Grade 1 Glucose intolerance Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Glucose Intolerance, CTCAE PT NCI Grade 1 Glucose intolerance PT CTCAE_v5 ctcae5:C144133 Present Present Grade 1 Glucosuria Grade 1 Glucosuria, CTCAE 10068405 C144133 Grade 1 Glucosuria Grade 1 Glucosuria Present NCI Present CTCAE_v5 Grade 1 Glucosuria PT CTCAE_v5 Grade 1 Glucosuria, CTCAE PT NCI ctcae5:C144134 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Growth Hormone Abnormal, CTCAE Grade 1 Growth hormone abnormal 10018748 C144134 Grade 1 Growth hormone abnormal Grade 1 Growth hormone abnormal Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Growth Hormone Abnormal, CTCAE PT NCI Grade 1 Growth hormone abnormal PT CTCAE_v5 ctcae5:C144135 Reduction in growth velocity by 10-29% ideally measured over the period of a year Reduction in growth velocity by 10-29% ideally measured over the period of a year Grade 1 Growth Suppression, CTCAE Grade 1 Growth suppression 10018761 C144135 Grade 1 Growth suppression Grade 1 Growth suppression Reduction in growth velocity by 10-29% ideally measured over the period of a year NCI Reduction in growth velocity by 10-29% ideally measured over the period of a year CTCAE_v5 Grade 1 Growth Suppression, CTCAE PT NCI Grade 1 Growth suppression PT CTCAE_v5 ctcae5:C144136 Mild symptoms Mild symptoms Grade 1 Guillain-Barre Syndrome, CTCAE Grade 1 Guillain-Barre syndrome 10018767 C144136 Grade 1 Guillain-Barre syndrome Grade 1 Guillain-Barre syndrome Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Guillain-Barre Syndrome, CTCAE PT NCI Grade 1 Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C144137 Local therapy indicated (swish and swallow) Local therapy indicated (swish and swallow) Grade 1 Gum Infection, CTCAE Grade 1 Gum infection 10018784 C144137 Grade 1 Gum infection Grade 1 Gum infection Local therapy indicated (swish and swallow) NCI Local therapy indicated (swish and swallow) CTCAE_v5 Grade 1 Gum Infection, CTCAE PT NCI Grade 1 Gum infection PT CTCAE_v5 ctcae5:C144138 Asymptomatic Asymptomatic Grade 1 Gynecomastia Grade 1 Gynecomastia, CTCAE 10018801 C144138 Grade 1 Gynecomastia Grade 1 Gynecomastia Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Gynecomastia PT CTCAE_v5 Grade 1 Gynecomastia, CTCAE PT NCI ctcae5:C144139 Present Present Grade 1 Hair Color Changes, CTCAE Grade 1 Hair color changes 10055525 C144139 Grade 1 Hair color changes Grade 1 Hair color changes Present NCI Present CTCAE_v5 Grade 1 Hair Color Changes, CTCAE PT NCI Grade 1 Hair color changes PT CTCAE_v5 ctcae5:C144140 Present Present Grade 1 Hair Texture Abnormal, CTCAE Grade 1 Hair texture abnormal 10019049 C144140 Grade 1 Hair texture abnormal Grade 1 Hair texture abnormal Present NCI Present CTCAE_v5 Grade 1 Hair Texture Abnormal, CTCAE PT NCI Grade 1 Hair texture abnormal PT CTCAE_v5 ctcae5:C144141 Mild hallucinations (e.g., perceptual distortions) Mild hallucinations (e.g., perceptual distortions) Grade 1 Hallucinations Grade 1 Hallucinations, CTCAE 10019077 C144141 Grade 1 Hallucinations Grade 1 Hallucinations Mild hallucinations (e.g., perceptual distortions) NCI Mild hallucinations (e.g., perceptual distortions) CTCAE_v5 Grade 1 Hallucinations PT CTCAE_v5 Grade 1 Hallucinations, CTCAE PT NCI ctcae5:C144142 <LLN <LLN Grade 1 Haptoglobin Decreased, CTCAE Grade 1 Haptoglobin decreased 10019150 C144142 Grade 1 Haptoglobin decreased Grade 1 Haptoglobin decreased <LLN NCI <LLN CTCAE_v5 Grade 1 Haptoglobin Decreased, CTCAE PT NCI Grade 1 Haptoglobin decreased PT CTCAE_v5 ctcae5:C144143 Mild pain Mild pain Grade 1 Headache Grade 1 Headache, CTCAE 10019211 C144143 Grade 1 Headache Grade 1 Headache Mild pain NCI Mild pain CTCAE_v5 Grade 1 Headache PT CTCAE_v5 Grade 1 Headache, CTCAE PT NCI ctcae5:C144144 Adults enrolled on a Monitoring Program (on a 1, 2, 4, 3, 6, and 8 kHz audiogram): Threshold shift of 15-25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Subjective change in hearing in the absence of documented hearing loss; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB hearing loss (HL) (i.e., 25 dB HL or greater); sensorineural hearing loss (SNHL) above 4 kHz (i.e., 6 or 8 kHz) in at least one ear Adults enrolled on a Monitoring Program (on a 1, 2, 4, 3, 6, and 8 kHz audiogram): Threshold shift of 15-25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Subjective change in hearing in the absence of documented hearing loss; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB hearing loss (HL) (i.e., 25 dB HL or greater); sensorineural hearing loss (SNHL) above 4 kHz (i.e., 6 or 8 kHz) in at least one ear Grade 1 Hearing Impaired, CTCAE Grade 1 Hearing impaired 10019245 C144144 Grade 1 Hearing impaired Grade 1 Hearing impaired Adults enrolled on a Monitoring Program (on a 1, 2, 4, 3, 6, and 8 kHz audiogram): Threshold shift of 15-25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Subjective change in hearing in the absence of documented hearing loss; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB hearing loss (HL) (i.e., 25 dB HL or greater); sensorineural hearing loss (SNHL) above 4 kHz (i.e., 6 or 8 kHz) in at least one ear NCI Adults enrolled on a Monitoring Program (on a 1, 2, 4, 3, 6, and 8 kHz audiogram): Threshold shift of 15-25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Subjective change in hearing in the absence of documented hearing loss; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB hearing loss (HL) (i.e., 25 dB HL or greater); sensorineural hearing loss (SNHL) above 4 kHz (i.e., 6 or 8 kHz) in at least one ear CTCAE_v5 Grade 1 Hearing Impaired, CTCAE PT NCI Grade 1 Hearing impaired PT CTCAE_v5 ctcae5:C144145 Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities Grade 1 Heart Failure, CTCAE Grade 1 Heart failure 10019279 C144145 Grade 1 Heart failure Grade 1 Heart failure Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities NCI Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities CTCAE_v5 Grade 1 Heart Failure, CTCAE PT NCI Grade 1 Heart failure PT CTCAE_v5 ctcae5:C144146 Minimal bleeding identified on imaging study or laparoscopy; intervention not indicated Minimal bleeding identified on imaging study or laparoscopy; intervention not indicated Grade 1 Hematosalpinx Grade 1 Hematosalpinx, CTCAE 10060602 C144146 Grade 1 Hematosalpinx Grade 1 Hematosalpinx Minimal bleeding identified on imaging study or laparoscopy; intervention not indicated NCI Minimal bleeding identified on imaging study or laparoscopy; intervention not indicated CTCAE_v5 Grade 1 Hematosalpinx PT CTCAE_v5 Grade 1 Hematosalpinx, CTCAE PT NCI ctcae5:C144147 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hematuria Grade 1 Hematuria, CTCAE 10019450 C144147 Grade 1 Hematuria Grade 1 Hematuria Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hematuria PT CTCAE_v5 Grade 1 Hematuria, CTCAE PT NCI ctcae5:C144148 Increase in >0-2 g/dL Increase in >0-2 g/dL Grade 1 Hemoglobin Increased, CTCAE Grade 1 Hemoglobin increased 10055599 C144148 Grade 1 Hemoglobin increased Grade 1 Hemoglobin increased Increase in >0-2 g/dL NCI Increase in >0-2 g/dL CTCAE_v5 Grade 1 Hemoglobin Increased, CTCAE PT NCI Grade 1 Hemoglobin increased PT CTCAE_v5 ctcae5:C144149 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hemorrhoidal Hemorrhage, CTCAE Grade 1 Hemorrhoidal hemorrhage 10060640 C144149 Grade 1 Hemorrhoidal hemorrhage Grade 1 Hemorrhoidal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hemorrhoidal Hemorrhage, CTCAE PT NCI Grade 1 Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C144150 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hepatic Hemorrhage, CTCAE Grade 1 Hepatic hemorrhage 10019678 C144150 Grade 1 Hepatic hemorrhage Grade 1 Hepatic hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hepatic Hemorrhage, CTCAE PT NCI Grade 1 Hepatic hemorrhage PT CTCAE_v5 ctcae5:C144151 Mild pain Mild pain Grade 1 Hepatic Pain, CTCAE Grade 1 Hepatic pain 10019705 C144151 Grade 1 Hepatic pain Grade 1 Hepatic pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Hepatic Pain, CTCAE PT NCI Grade 1 Hepatic pain PT CTCAE_v5 ctcae5:C144152 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Hepatitis B Reactivation, CTCAE Grade 1 Hepatitis B reactivation 10058827 C144152 Grade 1 Hepatitis B reactivation Grade 1 Hepatitis B reactivation Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hepatitis B Reactivation, CTCAE PT NCI Grade 1 Hepatitis B reactivation PT CTCAE_v5 ctcae5:C144153 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Hepatitis Viral, CTCAE Grade 1 Hepatitis viral 10019799 C144153 Grade 1 Hepatitis viral Grade 1 Hepatitis viral Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Hepatitis Viral, CTCAE PT NCI Grade 1 Hepatitis viral PT CTCAE_v5 ctcae5:C144154 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Hepatobiliary Disorders - Other, Specify, CTCAE Grade 1 Hepatobiliary disorders - Other, specify 10019805 C144154 Grade 1 Hepatobiliary disorders - Other, specify Grade 1 Hepatobiliary disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Grade 1 Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C144155 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Herpes Simplex Reactivation, CTCAE Grade 1 Herpes simplex reactivation 10080137 C144155 Grade 1 Herpes simplex reactivation Grade 1 Herpes simplex reactivation Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Herpes Simplex Reactivation, CTCAE PT NCI Grade 1 Herpes simplex reactivation PT CTCAE_v5 ctcae5:C144156 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hiccups Grade 1 Hiccups, CTCAE 10020039 C144156 Grade 1 Hiccups Grade 1 Hiccups Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hiccups PT CTCAE_v5 Grade 1 Hiccups, CTCAE PT NCI ctcae5:C144157 In women, increase in length, thickness or density of hair in a male distribution that the patient is able to camouflage by periodic shaving, bleaching, or removal of hair In women, increase in length, thickness or density of hair in a male distribution that the patient is able to camouflage by periodic shaving, bleaching, or removal of hair Grade 1 Hirsutism Grade 1 Hirsutism, CTCAE 10020112 C144157 Grade 1 Hirsutism Grade 1 Hirsutism In women, increase in length, thickness or density of hair in a male distribution that the patient is able to camouflage by periodic shaving, bleaching, or removal of hair NCI In women, increase in length, thickness or density of hair in a male distribution that the patient is able to camouflage by periodic shaving, bleaching, or removal of hair CTCAE_v5 Grade 1 Hirsutism PT CTCAE_v5 Grade 1 Hirsutism, CTCAE PT NCI ctcae5:C144158 Mild or intermittent voice change; fully understandable; self-resolves Mild or intermittent voice change; fully understandable; self-resolves Grade 1 Hoarseness Grade 1 Hoarseness, CTCAE 10020201 C144158 Grade 1 Hoarseness Grade 1 Hoarseness Mild or intermittent voice change; fully understandable; self-resolves NCI Mild or intermittent voice change; fully understandable; self-resolves CTCAE_v5 Grade 1 Hoarseness PT CTCAE_v5 Grade 1 Hoarseness, CTCAE PT NCI ctcae5:C144159 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hot Flashes, CTCAE Grade 1 Hot flashes 10020407 C144159 Grade 1 Hot flashes Grade 1 Hot flashes Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hot Flashes, CTCAE PT NCI Grade 1 Hot flashes PT CTCAE_v5 ctcae5:C144160 Corrected serum calcium of >ULN-11.5 mg/dL; >ULN-2.9 mmol/L; Ionized calcium >ULN-1.5 mmol/L Corrected serum calcium of >ULN-11.5 mg/dL; >ULN-2.9 mmol/L; Ionized calcium >ULN-1.5 mmol/L Grade 1 Hypercalcemia Grade 1 Hypercalcemia, CTCAE 10020587 C144160 Grade 1 Hypercalcemia Grade 1 Hypercalcemia Corrected serum calcium of >ULN-11.5 mg/dL; >ULN-2.9 mmol/L; Ionized calcium >ULN-1.5 mmol/L NCI Corrected serum calcium of >ULN-11.5 mg/dL; >ULN-2.9 mmol/L; Ionized calcium >ULN-1.5 mmol/L CTCAE_v5 Grade 1 Hypercalcemia PT CTCAE_v5 Grade 1 Hypercalcemia, CTCAE PT NCI ctcae5:C144161 Abnormal glucose above baseline with no medical intervention Abnormal glucose above baseline with no medical intervention Grade 1 Hyperglycemia Grade 1 Hyperglycemia, CTCAE 10020639 C144161 Grade 1 Hyperglycemia Grade 1 Hyperglycemia Abnormal glucose above baseline with no medical intervention NCI Abnormal glucose above baseline with no medical intervention CTCAE_v5 Grade 1 Hyperglycemia PT CTCAE_v5 Grade 1 Hyperglycemia, CTCAE PT NCI ctcae5:C144162 Limited to one site (palms, soles, or axillae); self care interventions Limited to one site (palms, soles, or axillae); self care interventions Grade 1 Hyperhidrosis Grade 1 Hyperhidrosis, CTCAE 10020642 C144162 Grade 1 Hyperhidrosis Grade 1 Hyperhidrosis Limited to one site (palms, soles, or axillae); self care interventions NCI Limited to one site (palms, soles, or axillae); self care interventions CTCAE_v5 Grade 1 Hyperhidrosis PT CTCAE_v5 Grade 1 Hyperhidrosis, CTCAE PT NCI ctcae5:C144163 >ULN-5.5 mmol/L >ULN-5.5 mmol/L Grade 1 Hyperkalemia Grade 1 Hyperkalemia, CTCAE 10020647 C144163 Grade 1 Hyperkalemia Grade 1 Hyperkalemia >ULN-5.5 mmol/L NCI >ULN-5.5 mmol/L CTCAE_v5 Grade 1 Hyperkalemia PT CTCAE_v5 Grade 1 Hyperkalemia, CTCAE PT NCI ctcae5:C144164 Present Present Grade 1 Hyperkeratosis Grade 1 Hyperkeratosis, CTCAE 10020649 C144164 Grade 1 Hyperkeratosis Grade 1 Hyperkeratosis Present NCI Present CTCAE_v5 Grade 1 Hyperkeratosis PT CTCAE_v5 Grade 1 Hyperkeratosis, CTCAE PT NCI ctcae5:C144165 Requiring diet changes Requiring diet changes Grade 1 Hyperlipidemia Grade 1 Hyperlipidemia, CTCAE 10020667 C144165 Grade 1 Hyperlipidemia Grade 1 Hyperlipidemia Requiring diet changes NCI Requiring diet changes CTCAE_v5 Grade 1 Hyperlipidemia PT CTCAE_v5 Grade 1 Hyperlipidemia, CTCAE PT NCI ctcae5:C144166 >ULN-3.0 mg/dL; >ULN-1.23 mmol/L >ULN-3.0 mg/dL; >ULN-1.23 mmol/L Grade 1 Hypermagnesemia Grade 1 Hypermagnesemia, CTCAE 10020670 C144166 Grade 1 Hypermagnesemia Grade 1 Hypermagnesemia >ULN-3.0 mg/dL; >ULN-1.23 mmol/L NCI >ULN-3.0 mg/dL; >ULN-1.23 mmol/L CTCAE_v5 Grade 1 Hypermagnesemia PT CTCAE_v5 Grade 1 Hypermagnesemia, CTCAE PT NCI ctcae5:C144167 >ULN-150 mmol/L >ULN-150 mmol/L Grade 1 Hypernatremia Grade 1 Hypernatremia, CTCAE 10020680 C144167 Grade 1 Hypernatremia Grade 1 Hypernatremia >ULN-150 mmol/L NCI >ULN-150 mmol/L CTCAE_v5 Grade 1 Hypernatremia PT CTCAE_v5 Grade 1 Hypernatremia, CTCAE PT NCI ctcae5:C144168 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hyperparathyroidism Grade 1 Hyperparathyroidism, CTCAE 10020705 C144168 Grade 1 Hyperparathyroidism Grade 1 Hyperparathyroidism Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hyperparathyroidism PT CTCAE_v5 Grade 1 Hyperparathyroidism, CTCAE PT NCI ctcae5:C144169 Laboratory finding only and intervention not indicated Laboratory finding only and intervention not indicated Grade 1 Hyperphosphatemia Grade 1 Hyperphosphatemia, CTCAE 10020712 C144169 Grade 1 Hyperphosphatemia Grade 1 Hyperphosphatemia Laboratory finding only and intervention not indicated NCI Laboratory finding only and intervention not indicated CTCAE_v5 Grade 1 Hyperphosphatemia PT CTCAE_v5 Grade 1 Hyperphosphatemia, CTCAE PT NCI ctcae5:C144170 Mild increased need for sleep Mild increased need for sleep Grade 1 Hypersomnia Grade 1 Hypersomnia, CTCAE 10020765 C144170 Grade 1 Hypersomnia Grade 1 Hypersomnia Mild increased need for sleep NCI Mild increased need for sleep CTCAE_v5 Grade 1 Hypersomnia PT CTCAE_v5 Grade 1 Hypersomnia, CTCAE PT NCI ctcae5:C144171 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hyperthyroidism Grade 1 Hyperthyroidism, CTCAE 10020850 C144171 Grade 1 Hyperthyroidism Grade 1 Hyperthyroidism Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hyperthyroidism PT CTCAE_v5 Grade 1 Hyperthyroidism, CTCAE PT NCI ctcae5:C144172 Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal Grade 1 Hypertrichosis Grade 1 Hypertrichosis, CTCAE 10020864 C144172 Grade 1 Hypertrichosis Grade 1 Hypertrichosis Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal NCI Increase in length, thickness or density of hair that the patient is either able to camouflage by periodic shaving or removal of hairs or is not concerned enough about the overgrowth to use any form of hair removal CTCAE_v5 Grade 1 Hypertrichosis PT CTCAE_v5 Grade 1 Hypertrichosis, CTCAE PT NCI ctcae5:C144173 150 mg/dL-300 mg/dL; 1.71 mmol/L-3.42 mmol/L 150 mg/dL-300 mg/dL; 1.71 mmol/L-3.42 mmol/L Grade 1 Hypertriglyceridemia Grade 1 Hypertriglyceridemia, CTCAE 10020870 C144173 Grade 1 Hypertriglyceridemia Grade 1 Hypertriglyceridemia 150 mg/dL-300 mg/dL; 1.71 mmol/L-3.42 mmol/L NCI 150 mg/dL-300 mg/dL; 1.71 mmol/L-3.42 mmol/L CTCAE_v5 Grade 1 Hypertriglyceridemia PT CTCAE_v5 Grade 1 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C144174 >ULN without physiologic consequences >ULN without physiologic consequences Grade 1 Hyperuricemia Grade 1 Hyperuricemia, CTCAE 10020907 C144174 Grade 1 Hyperuricemia Grade 1 Hyperuricemia >ULN without physiologic consequences NCI >ULN without physiologic consequences CTCAE_v5 Grade 1 Hyperuricemia PT CTCAE_v5 Grade 1 Hyperuricemia, CTCAE PT NCI ctcae5:C144175 <LLN-3 g/dL; <LLN-30 g/L <LLN-3 g/dL; <LLN-30 g/L Grade 1 Hypoalbuminemia Grade 1 Hypoalbuminemia, CTCAE 10020943 C144175 Grade 1 Hypoalbuminemia Grade 1 Hypoalbuminemia <LLN-3 g/dL; <LLN-30 g/L NCI <LLN-3 g/dL; <LLN-30 g/L CTCAE_v5 Grade 1 Hypoalbuminemia PT CTCAE_v5 Grade 1 Hypoalbuminemia, CTCAE PT NCI ctcae5:C144176 Corrected serum calcium of <LLN-8.0 mg/dL; <LLN-2.0 mmol/L; Ionized calcium <LLN-1.0 mmol/L Corrected serum calcium of <LLN-8.0 mg/dL; <LLN-2.0 mmol/L; Ionized calcium <LLN-1.0 mmol/L Grade 1 Hypocalcemia Grade 1 Hypocalcemia, CTCAE 10020949 C144176 Grade 1 Hypocalcemia Grade 1 Hypocalcemia Corrected serum calcium of <LLN-8.0 mg/dL; <LLN-2.0 mmol/L; Ionized calcium <LLN-1.0 mmol/L NCI Corrected serum calcium of <LLN-8.0 mg/dL; <LLN-2.0 mmol/L; Ionized calcium <LLN-1.0 mmol/L CTCAE_v5 Grade 1 Hypocalcemia PT CTCAE_v5 Grade 1 Hypocalcemia, CTCAE PT NCI ctcae5:C144177 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hypoglossal Nerve Disorder, CTCAE Grade 1 Hypoglossal nerve disorder 10061212 C144177 Grade 1 Hypoglossal nerve disorder Grade 1 Hypoglossal nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hypoglossal Nerve Disorder, CTCAE PT NCI Grade 1 Hypoglossal nerve disorder PT CTCAE_v5 ctcae5:C144178 <LLN-55 mg/dL; <LLN-3.0 mmol/L <LLN-55 mg/dL; <LLN-3.0 mmol/L Grade 1 Hypoglycemia Grade 1 Hypoglycemia, CTCAE 10021005 C144178 Grade 1 Hypoglycemia Grade 1 Hypoglycemia <LLN-55 mg/dL; <LLN-3.0 mmol/L NCI <LLN-55 mg/dL; <LLN-3.0 mmol/L CTCAE_v5 Grade 1 Hypoglycemia PT CTCAE_v5 Grade 1 Hypoglycemia, CTCAE PT NCI ctcae5:C144179 <LLN-3.0 mmol/L <LLN-3.0 mmol/L Grade 1 Hypokalemia Grade 1 Hypokalemia, CTCAE 10021018 C144179 Grade 1 Hypokalemia Grade 1 Hypokalemia <LLN-3.0 mmol/L NCI <LLN-3.0 mmol/L CTCAE_v5 Grade 1 Hypokalemia PT CTCAE_v5 Grade 1 Hypokalemia, CTCAE PT NCI ctcae5:C144180 <LLN-1.2 mg/dL; <LLN-0.5 mmol/L <LLN-1.2 mg/dL; <LLN-0.5 mmol/L Grade 1 Hypomagnesemia Grade 1 Hypomagnesemia, CTCAE 10021028 C144180 Grade 1 Hypomagnesemia Grade 1 Hypomagnesemia <LLN-1.2 mg/dL; <LLN-0.5 mmol/L NCI <LLN-1.2 mg/dL; <LLN-0.5 mmol/L CTCAE_v5 Grade 1 Hypomagnesemia PT CTCAE_v5 Grade 1 Hypomagnesemia, CTCAE PT NCI ctcae5:C144181 <LLN-130 mmol/L <LLN-130 mmol/L Grade 1 Hyponatremia Grade 1 Hyponatremia, CTCAE 10021038 C144181 Grade 1 Hyponatremia Grade 1 Hyponatremia <LLN-130 mmol/L NCI <LLN-130 mmol/L CTCAE_v5 Grade 1 Hyponatremia PT CTCAE_v5 Grade 1 Hyponatremia, CTCAE PT NCI ctcae5:C144182 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hypoparathyroidism Grade 1 Hypoparathyroidism, CTCAE 10021041 C144182 Grade 1 Hypoparathyroidism Grade 1 Hypoparathyroidism Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hypoparathyroidism PT CTCAE_v5 Grade 1 Hypoparathyroidism, CTCAE PT NCI ctcae5:C144183 Laboratory finding only and intervention not indicated Laboratory finding only and intervention not indicated Grade 1 Hypophosphatemia Grade 1 Hypophosphatemia, CTCAE 10021059 C144183 Grade 1 Hypophosphatemia Grade 1 Hypophosphatemia Laboratory finding only and intervention not indicated NCI Laboratory finding only and intervention not indicated CTCAE_v5 Grade 1 Hypophosphatemia PT CTCAE_v5 Grade 1 Hypophosphatemia, CTCAE PT NCI ctcae5:C144184 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Hypophysitis Grade 1 Hypophysitis, CTCAE 10062767 C144184 Grade 1 Hypophysitis Grade 1 Hypophysitis Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hypophysitis PT CTCAE_v5 Grade 1 Hypophysitis, CTCAE PT NCI ctcae5:C144185 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Hypopituitarism Grade 1 Hypopituitarism, CTCAE 10021067 C144185 Grade 1 Hypopituitarism Grade 1 Hypopituitarism Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hypopituitarism PT CTCAE_v5 Grade 1 Hypopituitarism, CTCAE PT NCI ctcae5:C144186 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hypothyroidism Grade 1 Hypothyroidism, CTCAE 10021114 C144186 Grade 1 Hypothyroidism Grade 1 Hypothyroidism Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hypothyroidism PT CTCAE_v5 Grade 1 Hypothyroidism, CTCAE PT NCI ctcae5:C144190 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ileal Stenosis, CTCAE Grade 1 Ileal stenosis 10021307 C144190 Grade 1 Ileal stenosis Grade 1 Ileal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ileal Stenosis, CTCAE PT NCI Grade 1 Ileal stenosis PT CTCAE_v5 ctcae5:C144193 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Immune System Disorders - Other, Specify, CTCAE Grade 1 Immune system disorders - Other, specify 10021428 C144193 Grade 1 Immune system disorders - Other, specify Grade 1 Immune system disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Immune System Disorders - Other, Specify, CTCAE PT NCI Grade 1 Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C144194 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Infections and Infestations - Other, Specify, CTCAE Grade 1 Infections and infestations - Other, specify 10021881 C144194 Grade 1 Infections and infestations - Other, specify Grade 1 Infections and infestations - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Infections and Infestations - Other, Specify, CTCAE PT NCI Grade 1 Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C144195 Mild transient reaction; infusion interruption not indicated; intervention not indicated Mild transient reaction; infusion interruption not indicated; intervention not indicated Grade 1 Infusion Related Reaction, CTCAE Grade 1 Infusion related reaction 10051792 C144195 Grade 1 Infusion related reaction Grade 1 Infusion related reaction Mild transient reaction; infusion interruption not indicated; intervention not indicated NCI Mild transient reaction; infusion interruption not indicated; intervention not indicated CTCAE_v5 Grade 1 Infusion Related Reaction, CTCAE PT NCI Grade 1 Infusion related reaction PT CTCAE_v5 ctcae5:C144196 Painless edema Painless edema Grade 1 Infusion Site Extravasation, CTCAE Grade 1 Infusion site extravasation 10064774 C144196 Grade 1 Infusion site extravasation Grade 1 Infusion site extravasation Painless edema NCI Painless edema CTCAE_v5 Grade 1 Infusion Site Extravasation, CTCAE PT NCI Grade 1 Infusion site extravasation PT CTCAE_v5 ctcae5:C144197 Tenderness with or without associated symptoms (e.g., warmth, erythema, itching) Tenderness with or without associated symptoms (e.g., warmth, erythema, itching) Grade 1 Injection Site Reaction, CTCAE Grade 1 Injection site reaction 10022095 C144197 Grade 1 Injection site reaction Grade 1 Injection site reaction Tenderness with or without associated symptoms (e.g., warmth, erythema, itching) NCI Tenderness with or without associated symptoms (e.g., warmth, erythema, itching) CTCAE_v5 Grade 1 Injection Site Reaction, CTCAE PT NCI Grade 1 Injection site reaction PT CTCAE_v5 ctcae5:C144199 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Injury To Superior Vena Cava, CTCAE Grade 1 Injury to superior vena cava 10022356 C144199 Grade 1 Injury to superior vena cava Grade 1 Injury to superior vena cava Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Injury To Superior Vena Cava, CTCAE PT NCI Grade 1 Injury to superior vena cava PT CTCAE_v5 ctcae5:C144200 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Grade 1 Injury, poisoning and procedural complications - Other, specify 10022117 C144200 Grade 1 Injury, poisoning and procedural complications - Other, specify Grade 1 Injury, poisoning and procedural complications - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Grade 1 Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C144201 >1.2-1.5; >1-1.5 x baseline if on anticoagulation; monitoring only indicated >1.2-1.5; >1-1.5 x baseline if on anticoagulation; monitoring only indicated Grade 1 INR Increased, CTCAE Grade 1 INR increased 10022402 C144201 Grade 1 INR increased Grade 1 INR increased >1.2-1.5; >1-1.5 x baseline if on anticoagulation; monitoring only indicated NCI >1.2-1.5; >1-1.5 x baseline if on anticoagulation; monitoring only indicated CTCAE_v5 Grade 1 INR Increased, CTCAE PT NCI Grade 1 INR increased PT CTCAE_v5 ctcae5:C144202 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Intestinal Stoma Leak, CTCAE Grade 1 Intestinal stoma leak 10059095 C144202 Grade 1 Intestinal stoma leak Grade 1 Intestinal stoma leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Intestinal Stoma Leak, CTCAE PT NCI Grade 1 Intestinal stoma leak PT CTCAE_v5 ctcae5:C144203 Minimal bleeding identified on clinical exam; intervention not indicated Minimal bleeding identified on clinical exam; intervention not indicated Grade 1 Intestinal Stoma Site Bleeding, CTCAE Grade 1 Intestinal stoma site bleeding 10049468 C144203 Grade 1 Intestinal stoma site bleeding Grade 1 Intestinal stoma site bleeding Minimal bleeding identified on clinical exam; intervention not indicated NCI Minimal bleeding identified on clinical exam; intervention not indicated CTCAE_v5 Grade 1 Intestinal Stoma Site Bleeding, CTCAE PT NCI Grade 1 Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C144204 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Intracranial Hemorrhage, CTCAE Grade 1 Intracranial hemorrhage 10022763 C144204 Grade 1 Intracranial hemorrhage Grade 1 Intracranial hemorrhage Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Intracranial Hemorrhage, CTCAE PT NCI Grade 1 Intracranial hemorrhage PT CTCAE_v5 ctcae5:C144205 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Arterial Injury, CTCAE Grade 1 Intraoperative arterial injury 10065826 C144205 Grade 1 Intraoperative arterial injury Grade 1 Intraoperative arterial injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Arterial Injury, CTCAE PT NCI Grade 1 Intraoperative arterial injury PT CTCAE_v5 ctcae5:C144206 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Breast Injury, CTCAE Grade 1 Intraoperative breast injury 10065831 C144206 Grade 1 Intraoperative breast injury Grade 1 Intraoperative breast injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Breast Injury, CTCAE PT NCI Grade 1 Intraoperative breast injury PT CTCAE_v5 ctcae5:C144207 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Ear Injury, CTCAE Grade 1 Intraoperative ear injury 10065844 C144207 Grade 1 Intraoperative ear injury Grade 1 Intraoperative ear injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Ear Injury, CTCAE PT NCI Grade 1 Intraoperative ear injury PT CTCAE_v5 ctcae5:C144208 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Endocrine Injury, CTCAE Grade 1 Intraoperative endocrine injury 10065834 C144208 Grade 1 Intraoperative endocrine injury Grade 1 Intraoperative endocrine injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Endocrine Injury, CTCAE PT NCI Grade 1 Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C144209 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Gastrointestinal Injury, CTCAE Grade 1 Intraoperative gastrointestinal injury 10065825 C144209 Grade 1 Intraoperative gastrointestinal injury Grade 1 Intraoperative gastrointestinal injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Grade 1 Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C144210 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Head and Neck Injury, CTCAE Grade 1 Intraoperative head and neck injury 10065842 C144210 Grade 1 Intraoperative head and neck injury Grade 1 Intraoperative head and neck injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Head and Neck Injury, CTCAE PT NCI Grade 1 Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C144211 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Hepatobiliary Injury, CTCAE Grade 1 Intraoperative hepatobiliary injury 10065827 C144211 Grade 1 Intraoperative hepatobiliary injury Grade 1 Intraoperative hepatobiliary injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Grade 1 Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C144212 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Musculoskeletal Injury, CTCAE Grade 1 Intraoperative musculoskeletal injury 10065829 C144212 Grade 1 Intraoperative musculoskeletal injury Grade 1 Intraoperative musculoskeletal injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Grade 1 Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C144213 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Neurological Injury, CTCAE Grade 1 Intraoperative neurological injury 10065830 C144213 Grade 1 Intraoperative neurological injury Grade 1 Intraoperative neurological injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Neurological Injury, CTCAE PT NCI Grade 1 Intraoperative neurological injury PT CTCAE_v5 ctcae5:C144214 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Ocular Injury, CTCAE Grade 1 Intraoperative ocular injury 10065841 C144214 Grade 1 Intraoperative ocular injury Grade 1 Intraoperative ocular injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Ocular Injury, CTCAE PT NCI Grade 1 Intraoperative ocular injury PT CTCAE_v5 ctcae5:C144215 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Renal Injury, CTCAE Grade 1 Intraoperative renal injury 10065845 C144215 Grade 1 Intraoperative renal injury Grade 1 Intraoperative renal injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Renal Injury, CTCAE PT NCI Grade 1 Intraoperative renal injury PT CTCAE_v5 ctcae5:C144216 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Reproductive Tract Injury, CTCAE Grade 1 Intraoperative reproductive tract injury 10065840 C144216 Grade 1 Intraoperative reproductive tract injury Grade 1 Intraoperative reproductive tract injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Grade 1 Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C144217 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Respiratory Injury, CTCAE Grade 1 Intraoperative respiratory injury 10065832 C144217 Grade 1 Intraoperative respiratory injury Grade 1 Intraoperative respiratory injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Respiratory Injury, CTCAE PT NCI Grade 1 Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C144218 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Urinary Injury, CTCAE Grade 1 Intraoperative urinary injury 10065828 C144218 Grade 1 Intraoperative urinary injury Grade 1 Intraoperative urinary injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Urinary Injury, CTCAE PT NCI Grade 1 Intraoperative urinary injury PT CTCAE_v5 ctcae5:C144219 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 1 Intraoperative Venous Injury, CTCAE Grade 1 Intraoperative venous injury 10065848 C144219 Grade 1 Intraoperative venous injury Grade 1 Intraoperative venous injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 1 Intraoperative Venous Injury, CTCAE PT NCI Grade 1 Intraoperative venous injury PT CTCAE_v5 ctcae5:C144220 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Investigations - Other, Specify, CTCAE Grade 1 Investigations - Other, specify 10022891 C144220 Grade 1 Investigations - Other, specify Grade 1 Investigations - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Investigations - Other, Specify, CTCAE PT NCI Grade 1 Investigations - Other, specify PT CTCAE_v5 ctcae5:C144221 Intermittent/irregular menses for no more than 3 consecutive menstrual cycles Intermittent/irregular menses for no more than 3 consecutive menstrual cycles Grade 1 Irregular Menstruation, CTCAE Grade 1 Irregular menstruation 10022992 C144221 Grade 1 Irregular menstruation Grade 1 Irregular menstruation Intermittent/irregular menses for no more than 3 consecutive menstrual cycles NCI Intermittent/irregular menses for no more than 3 consecutive menstrual cycles CTCAE_v5 Grade 1 Irregular Menstruation, CTCAE PT NCI Grade 1 Irregular menstruation PT CTCAE_v5 ctcae5:C144222 Mild; easily consolable Mild; easily consolable Grade 1 Irritability Grade 1 Irritability, CTCAE 10022998 C144222 Grade 1 Irritability Grade 1 Irritability Mild; easily consolable NCI Mild; easily consolable CTCAE_v5 Grade 1 Irritability PT CTCAE_v5 Grade 1 Irritability, CTCAE PT NCI ctcae5:C144223 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ischemia Cerebrovascular, CTCAE Grade 1 Ischemia cerebrovascular 10023030 C144223 Grade 1 Ischemia cerebrovascular Grade 1 Ischemia cerebrovascular Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ischemia Cerebrovascular, CTCAE PT NCI Grade 1 Ischemia cerebrovascular PT CTCAE_v5 ctcae5:C144227 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Jejunal Stenosis, CTCAE Grade 1 Jejunal stenosis 10023176 C144227 Grade 1 Jejunal stenosis Grade 1 Jejunal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Jejunal Stenosis, CTCAE PT NCI Grade 1 Jejunal stenosis PT CTCAE_v5 ctcae5:C144229 Mild restriction of rotation or flexion between 60-70 degrees Mild restriction of rotation or flexion between 60-70 degrees Grade 1 Joint Range of Motion Decreased Cervical Spine, CTCAE Grade 1 Joint range of motion decreased cervical spine 10065796 C144229 Grade 1 Joint range of motion decreased cervical spine Grade 1 Joint range of motion decreased cervical spine Mild restriction of rotation or flexion between 60-70 degrees NCI Mild restriction of rotation or flexion between 60-70 degrees CTCAE_v5 Grade 1 Joint Range of Motion Decreased Cervical Spine, CTCAE PT NCI Grade 1 Joint range of motion decreased cervical spine PT CTCAE_v5 ctcae5:C144230 Stiffness; difficulty bending to the floor to pick up a very light object but able to do athletic activity Stiffness; difficulty bending to the floor to pick up a very light object but able to do athletic activity Grade 1 Joint Range of Motion Decreased Lumbar Spine, CTCAE Grade 1 Joint range of motion decreased lumbar spine 10065800 C144230 Grade 1 Joint range of motion decreased lumbar spine Grade 1 Joint range of motion decreased lumbar spine Stiffness; difficulty bending to the floor to pick up a very light object but able to do athletic activity NCI Stiffness; difficulty bending to the floor to pick up a very light object but able to do athletic activity CTCAE_v5 Grade 1 Joint Range of Motion Decreased Lumbar Spine, CTCAE PT NCI Grade 1 Joint range of motion decreased lumbar spine PT CTCAE_v5 ctcae5:C144231 <=25% loss of ROM (range of motion); decreased ROM limiting athletic activity <=25% loss of ROM (range of motion); decreased ROM limiting athletic activity Grade 1 Joint Range of Motion Decreased, CTCAE Grade 1 Joint range of motion decreased 10048706 C144231 Grade 1 Joint range of motion decreased Grade 1 Joint range of motion decreased <=25% loss of ROM (range of motion); decreased ROM limiting athletic activity NCI <=25% loss of ROM (range of motion); decreased ROM limiting athletic activity CTCAE_v5 Grade 1 Joint Range of Motion Decreased, CTCAE PT NCI Grade 1 Joint range of motion decreased PT CTCAE_v5 ctcae5:C144232 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Kidney Anastomotic Leak, CTCAE Grade 1 Kidney anastomotic leak 10065803 C144232 Grade 1 Kidney anastomotic leak Grade 1 Kidney anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Kidney Anastomotic Leak, CTCAE PT NCI Grade 1 Kidney anastomotic leak PT CTCAE_v5 ctcae5:C144233 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Kyphosis Grade 1 Kyphosis, CTCAE 10023509 C144233 Grade 1 Kyphosis Grade 1 Kyphosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Kyphosis PT CTCAE_v5 Grade 1 Kyphosis, CTCAE PT NCI ctcae5:C144234 Mild changes in lactation, not significantly affecting production or expression of breast milk Mild changes in lactation, not significantly affecting production or expression of breast milk Grade 1 Lactation Disorder, CTCAE Grade 1 Lactation disorder 10061261 C144234 Grade 1 Lactation disorder Grade 1 Lactation disorder Mild changes in lactation, not significantly affecting production or expression of breast milk NCI Mild changes in lactation, not significantly affecting production or expression of breast milk CTCAE_v5 Grade 1 Lactation Disorder, CTCAE PT NCI Grade 1 Lactation disorder PT CTCAE_v5 ctcae5:C144235 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Large Intestinal Anastomotic Leak, CTCAE Grade 1 Large intestinal anastomotic leak 10065891 C144235 Grade 1 Large intestinal anastomotic leak Grade 1 Large intestinal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Large Intestinal Anastomotic Leak, CTCAE PT NCI Grade 1 Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C144236 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Laryngeal Edema, CTCAE Grade 1 Laryngeal edema 10023838 C144236 Grade 1 Laryngeal edema Grade 1 Laryngeal edema Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Laryngeal Edema, CTCAE PT NCI Grade 1 Laryngeal edema PT CTCAE_v5 ctcae5:C144239 Mild sore throat; raspy voice Mild sore throat; raspy voice Grade 1 Laryngeal Inflammation, CTCAE Grade 1 Laryngeal inflammation 10065735 C144239 Grade 1 Laryngeal inflammation Grade 1 Laryngeal inflammation Mild sore throat; raspy voice NCI Mild sore throat; raspy voice CTCAE_v5 Grade 1 Laryngeal Inflammation, CTCAE PT NCI Grade 1 Laryngeal inflammation PT CTCAE_v5 ctcae5:C144240 Endoscopic findings only; mild discomfort with normal intake Endoscopic findings only; mild discomfort with normal intake Grade 1 Laryngeal Mucositis, CTCAE Grade 1 Laryngeal mucositis 10065880 C144240 Grade 1 Laryngeal mucositis Grade 1 Laryngeal mucositis Endoscopic findings only; mild discomfort with normal intake NCI Endoscopic findings only; mild discomfort with normal intake CTCAE_v5 Grade 1 Laryngeal Mucositis, CTCAE PT NCI Grade 1 Laryngeal mucositis PT CTCAE_v5 ctcae5:C144241 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Laryngeal Obstruction, CTCAE Grade 1 Laryngeal obstruction 10059639 C144241 Grade 1 Laryngeal obstruction Grade 1 Laryngeal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Laryngeal Obstruction, CTCAE PT NCI Grade 1 Laryngeal obstruction PT CTCAE_v5 ctcae5:C144242 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Laryngeal Stenosis, CTCAE Grade 1 Laryngeal stenosis 10023862 C144242 Grade 1 Laryngeal stenosis Grade 1 Laryngeal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Laryngeal Stenosis, CTCAE PT NCI Grade 1 Laryngeal stenosis PT CTCAE_v5 ctcae5:C144243 Mild symptoms; no anxiety; intervention not indicated Mild symptoms; no anxiety; intervention not indicated Grade 1 Laryngopharyngeal Dysesthesia, CTCAE Grade 1 Laryngopharyngeal dysesthesia 10062667 C144243 Grade 1 Laryngopharyngeal dysesthesia Grade 1 Laryngopharyngeal dysesthesia Mild symptoms; no anxiety; intervention not indicated NCI Mild symptoms; no anxiety; intervention not indicated CTCAE_v5 Grade 1 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Grade 1 Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C144244 Mild symptoms; reduced alertness and awareness Mild symptoms; reduced alertness and awareness Grade 1 Lethargy Grade 1 Lethargy, CTCAE 10024264 C144244 Grade 1 Lethargy Grade 1 Lethargy Mild symptoms; reduced alertness and awareness NCI Mild symptoms; reduced alertness and awareness CTCAE_v5 Grade 1 Lethargy PT CTCAE_v5 Grade 1 Lethargy, CTCAE PT NCI ctcae5:C144245 Asymptomatic; small focal T2/FLAIR hyperintensities; involving periventricular white matter or <1/3 of susceptible areas of cerebrum +/- mild increase in subarachnoid space (SAS) and/or mild ventriculomegaly Asymptomatic; small focal T2/FLAIR hyperintensities; involving periventricular white matter or <1/3 of susceptible areas of cerebrum +/- mild increase in subarachnoid space (SAS) and/or mild ventriculomegaly Grade 1 Leukoencephalopathy Grade 1 Leukoencephalopathy, CTCAE 10024382 C144245 Grade 1 Leukoencephalopathy Grade 1 Leukoencephalopathy Asymptomatic; small focal T2/FLAIR hyperintensities; involving periventricular white matter or <1/3 of susceptible areas of cerebrum +/- mild increase in subarachnoid space (SAS) and/or mild ventriculomegaly NCI Asymptomatic; small focal T2/FLAIR hyperintensities; involving periventricular white matter or <1/3 of susceptible areas of cerebrum +/- mild increase in subarachnoid space (SAS) and/or mild ventriculomegaly CTCAE_v5 Grade 1 Leukoencephalopathy PT CTCAE_v5 Grade 1 Leukoencephalopathy, CTCAE PT NCI ctcae5:C144246 Decrease in sexual interest not adversely affecting relationship Decrease in sexual interest not adversely affecting relationship Grade 1 Libido Decreased, CTCAE Grade 1 Libido decreased 10024419 C144246 Grade 1 Libido decreased Grade 1 Libido decreased Decrease in sexual interest not adversely affecting relationship NCI Decrease in sexual interest not adversely affecting relationship CTCAE_v5 Grade 1 Libido Decreased, CTCAE PT NCI Grade 1 Libido decreased PT CTCAE_v5 ctcae5:C144247 Present Present Grade 1 Libido Increased, CTCAE Grade 1 Libido increased 10024421 C144247 Grade 1 Libido increased Grade 1 Libido increased Present NCI Present CTCAE_v5 Grade 1 Libido Increased, CTCAE PT NCI Grade 1 Libido increased PT CTCAE_v5 ctcae5:C144248 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Lip Infection, CTCAE Grade 1 Lip infection 10065755 C144248 Grade 1 Lip infection Grade 1 Lip infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Lip Infection, CTCAE PT NCI Grade 1 Lip infection PT CTCAE_v5 ctcae5:C144249 >ULN-1.5 x ULN >ULN-1.5 x ULN Grade 1 Lipase Increased, CTCAE Grade 1 Lipase increased 10024574 C144249 Grade 1 Lipase increased Grade 1 Lipase increased >ULN-1.5 x ULN NCI >ULN-1.5 x ULN CTCAE_v5 Grade 1 Lipase Increased, CTCAE PT NCI Grade 1 Lipase increased PT CTCAE_v5 ctcae5:C144250 Asymptomatic and covering <10% BSA Asymptomatic and covering <10% BSA Grade 1 Lipohypertrophy Grade 1 Lipohypertrophy, CTCAE 10062315 C144250 Grade 1 Lipohypertrophy Grade 1 Lipohypertrophy Asymptomatic and covering <10% BSA NCI Asymptomatic and covering <10% BSA CTCAE_v5 Grade 1 Lipohypertrophy PT CTCAE_v5 Grade 1 Lipohypertrophy, CTCAE PT NCI ctcae5:C144251 Localized to dependent areas, no disability or functional impairment Localized to dependent areas, no disability or functional impairment Grade 1 Localized Edema, CTCAE Grade 1 Localized edema 10062466 C144251 Grade 1 Localized edema Grade 1 Localized edema Localized to dependent areas, no disability or functional impairment NCI Localized to dependent areas, no disability or functional impairment CTCAE_v5 Grade 1 Localized Edema, CTCAE PT NCI Grade 1 Localized edema PT CTCAE_v5 ctcae5:C144252 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Lordosis Grade 1 Lordosis, CTCAE 10024842 C144252 Grade 1 Lordosis Grade 1 Lordosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Lordosis PT CTCAE_v5 Grade 1 Lordosis, CTCAE PT NCI ctcae5:C144253 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Lower Gastrointestinal Hemorrhage, CTCAE Grade 1 Lower gastrointestinal hemorrhage 10051746 C144253 Grade 1 Lower gastrointestinal hemorrhage Grade 1 Lower gastrointestinal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 1 Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C144254 Trace thickening or faint discoloration Trace thickening or faint discoloration Grade 1 Lymphedema Grade 1 Lymphedema, CTCAE 10025233 C144254 Grade 1 Lymphedema Grade 1 Lymphedema Trace thickening or faint discoloration NCI Trace thickening or faint discoloration CTCAE_v5 Grade 1 Lymphedema PT CTCAE_v5 Grade 1 Lymphedema, CTCAE PT NCI ctcae5:C144255 <LLN-800/mm3; <LLN-0.8 x 10e9/L <LLN-800/mm3; <LLN-0.8 x 10e9/L Grade 1 Lymphocyte Count Decreased, CTCAE Grade 1 Lymphocyte count decreased 10025256 C144255 Grade 1 Lymphocyte count decreased Grade 1 Lymphocyte count decreased <LLN-800/mm3; <LLN-0.8 x 10e9/L NCI <LLN-800/mm3; <LLN-0.8 x 10e9/L CTCAE_v5 Grade 1 Lymphocyte Count Decreased, CTCAE PT NCI Grade 1 Lymphocyte count decreased PT CTCAE_v5 ctcae5:C144256 Uneasiness or lack of well being Uneasiness or lack of well being Grade 1 Malaise Grade 1 Malaise, CTCAE 10025482 C144256 Grade 1 Malaise Grade 1 Malaise Uneasiness or lack of well being NCI Uneasiness or lack of well being CTCAE_v5 Grade 1 Malaise PT CTCAE_v5 Grade 1 Malaise, CTCAE PT NCI ctcae5:C144257 Mild manic symptoms (e.g., elevated mood, rapid thoughts, rapid speech, decreased need for sleep) Mild manic symptoms (e.g., elevated mood, rapid thoughts, rapid speech, decreased need for sleep) Grade 1 Mania Grade 1 Mania, CTCAE 10026749 C144257 Grade 1 Mania Grade 1 Mania Mild manic symptoms (e.g., elevated mood, rapid thoughts, rapid speech, decreased need for sleep) NCI Mild manic symptoms (e.g., elevated mood, rapid thoughts, rapid speech, decreased need for sleep) CTCAE_v5 Grade 1 Mania PT CTCAE_v5 Grade 1 Mania, CTCAE PT NCI ctcae5:C144259 Mild symptoms Mild symptoms Grade 1 Meningismus Grade 1 Meningismus, CTCAE 10027198 C144259 Grade 1 Meningismus Grade 1 Meningismus Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Meningismus PT CTCAE_v5 Grade 1 Meningismus, CTCAE PT NCI ctcae5:C144260 Mild; iron supplements indicated Mild; iron supplements indicated Grade 1 Menorrhagia Grade 1 Menorrhagia, CTCAE 10027313 C144260 Grade 1 Menorrhagia Grade 1 Menorrhagia Mild; iron supplements indicated NCI Mild; iron supplements indicated CTCAE_v5 Grade 1 Menorrhagia PT CTCAE_v5 Grade 1 Menorrhagia, CTCAE PT NCI ctcae5:C144261 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Grade 1 Metabolism and nutrition disorders - Other, specify 10027433 C144261 Grade 1 Metabolism and nutrition disorders - Other, specify Grade 1 Metabolism and nutrition disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Grade 1 Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C144262 Serous otitis Serous otitis Grade 1 Middle Ear Inflammation, CTCAE Grade 1 Middle ear inflammation 10065838 C144262 Grade 1 Middle ear inflammation Grade 1 Middle ear inflammation Serous otitis NCI Serous otitis CTCAE_v5 Grade 1 Middle Ear Inflammation, CTCAE PT NCI Grade 1 Middle ear inflammation PT CTCAE_v5 ctcae5:C144263 Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Grade 1 Mitral Valve Disease, CTCAE Grade 1 Mitral valve disease 10061532 C144263 Grade 1 Mitral valve disease Grade 1 Mitral valve disease Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging NCI Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging CTCAE_v5 Grade 1 Mitral Valve Disease, CTCAE PT NCI Grade 1 Mitral valve disease PT CTCAE_v5 ctcae5:C144266 Mild symptoms Mild symptoms Grade 1 Movements Involuntary, CTCAE Grade 1 Movements involuntary 10028041 C144266 Grade 1 Movements involuntary Grade 1 Movements involuntary Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Movements Involuntary, CTCAE PT NCI Grade 1 Movements involuntary PT CTCAE_v5 ctcae5:C144267 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Mucosal Infection, CTCAE Grade 1 Mucosal infection 10065764 C144267 Grade 1 Mucosal infection Grade 1 Mucosal infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Mucosal Infection, CTCAE PT NCI Grade 1 Mucosal infection PT CTCAE_v5 ctcae5:C144268 Asymptomatic or mild symptoms; intervention not indicated Asymptomatic or mild symptoms; intervention not indicated Grade 1 Mucositis Oral, CTCAE Grade 1 Mucositis oral 10028130 C144268 Grade 1 Mucositis oral Grade 1 Mucositis oral Asymptomatic or mild symptoms; intervention not indicated NCI Asymptomatic or mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Mucositis Oral, CTCAE PT NCI Grade 1 Mucositis oral PT CTCAE_v5 ctcae5:C144269 Mild pain Mild pain Grade 1 Muscle Cramp, CTCAE Grade 1 Muscle cramp 10028294 C144269 Grade 1 Muscle cramp Grade 1 Muscle cramp Mild pain NCI Mild pain CTCAE_v5 Grade 1 Muscle Cramp, CTCAE PT NCI Grade 1 Muscle cramp PT CTCAE_v5 ctcae5:C144270 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Muscle Weakness Left-Sided, CTCAE Grade 1 Muscle weakness left-sided 10065780 C144270 Grade 1 Muscle weakness left-sided Grade 1 Muscle weakness left-sided Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Muscle Weakness Left-Sided, CTCAE PT NCI Grade 1 Muscle weakness left-sided PT CTCAE_v5 ctcae5:C144271 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Muscle Weakness Lower Limb, CTCAE Grade 1 Muscle weakness lower limb 10065776 C144271 Grade 1 Muscle weakness lower limb Grade 1 Muscle weakness lower limb Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Muscle Weakness Lower Limb, CTCAE PT NCI Grade 1 Muscle weakness lower limb PT CTCAE_v5 ctcae5:C144272 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Muscle Weakness Right-Sided, CTCAE Grade 1 Muscle weakness right-sided 10065794 C144272 Grade 1 Muscle weakness right-sided Grade 1 Muscle weakness right-sided Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Muscle Weakness Right-Sided, CTCAE PT NCI Grade 1 Muscle weakness right-sided PT CTCAE_v5 ctcae5:C144273 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Muscle Weakness Trunk, CTCAE Grade 1 Muscle weakness trunk 10065795 C144273 Grade 1 Muscle weakness trunk Grade 1 Muscle weakness trunk Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Muscle Weakness Trunk, CTCAE PT NCI Grade 1 Muscle weakness trunk PT CTCAE_v5 ctcae5:C144274 Symptomatic; perceived by patient but not evident on physical exam Symptomatic; perceived by patient but not evident on physical exam Grade 1 Muscle Weakness Upper Limb, CTCAE Grade 1 Muscle weakness upper limb 10065895 C144274 Grade 1 Muscle weakness upper limb Grade 1 Muscle weakness upper limb Symptomatic; perceived by patient but not evident on physical exam NCI Symptomatic; perceived by patient but not evident on physical exam CTCAE_v5 Grade 1 Muscle Weakness Upper Limb, CTCAE PT NCI Grade 1 Muscle weakness upper limb PT CTCAE_v5 ctcae5:C144275 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Grade 1 Musculoskeletal and connective tissue disorder - Other, specify 10028395 C144275 Grade 1 Musculoskeletal and connective tissue disorder - Other, specify Grade 1 Musculoskeletal and connective tissue disorder - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Grade 1 Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C144276 Cosmetically and functionally insignificant hypoplasia Cosmetically and functionally insignificant hypoplasia Grade 1 Musculoskeletal Deformity, CTCAE Grade 1 Musculoskeletal deformity 10065783 C144276 Grade 1 Musculoskeletal deformity Grade 1 Musculoskeletal deformity Cosmetically and functionally insignificant hypoplasia NCI Cosmetically and functionally insignificant hypoplasia CTCAE_v5 Grade 1 Musculoskeletal Deformity, CTCAE PT NCI Grade 1 Musculoskeletal deformity PT CTCAE_v5 ctcae5:C144277 Mild pain Mild pain Grade 1 Myalgia Grade 1 Myalgia, CTCAE 10028411 C144277 Grade 1 Myalgia Grade 1 Myalgia Mild pain NCI Mild pain CTCAE_v5 Grade 1 Myalgia PT CTCAE_v5 Grade 1 Myalgia, CTCAE PT NCI ctcae5:C144278 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Myasthenia Gravis, CTCAE Grade 1 Myasthenia gravis 10028417 C144278 Grade 1 Myasthenia gravis Grade 1 Myasthenia gravis Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Myasthenia Gravis, CTCAE PT NCI Grade 1 Myasthenia gravis PT CTCAE_v5 ctcae5:C144280 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Nail Discoloration, CTCAE Grade 1 Nail discoloration 10028691 C144280 Grade 1 Nail discoloration Grade 1 Nail discoloration Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Nail Discoloration, CTCAE PT NCI Grade 1 Nail discoloration PT CTCAE_v5 ctcae5:C144281 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Nail Infection, CTCAE Grade 1 Nail infection 10061304 C144281 Grade 1 Nail infection Grade 1 Nail infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Nail Infection, CTCAE PT NCI Grade 1 Nail infection PT CTCAE_v5 ctcae5:C144282 Asymptomatic separation of the nail bed from the nail plate or nail loss Asymptomatic separation of the nail bed from the nail plate or nail loss Grade 1 Nail Loss, CTCAE Grade 1 Nail loss 10049281 C144282 Grade 1 Nail loss Grade 1 Nail loss Asymptomatic separation of the nail bed from the nail plate or nail loss NCI Asymptomatic separation of the nail bed from the nail plate or nail loss CTCAE_v5 Grade 1 Nail Loss, CTCAE PT NCI Grade 1 Nail loss PT CTCAE_v5 ctcae5:C144283 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Nail Ridging, CTCAE Grade 1 Nail ridging 10062283 C144283 Grade 1 Nail ridging Grade 1 Nail ridging Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Nail Ridging, CTCAE PT NCI Grade 1 Nail ridging PT CTCAE_v5 ctcae5:C144284 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Nasal Congestion, CTCAE Grade 1 Nasal congestion 10028735 C144284 Grade 1 Nasal congestion Grade 1 Nasal congestion Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Nasal Congestion, CTCAE PT NCI Grade 1 Nasal congestion PT CTCAE_v5 ctcae5:C144285 Asymptomatic localized neck edema Asymptomatic localized neck edema Grade 1 Neck Edema, CTCAE Grade 1 Neck edema 10054482 C144285 Grade 1 Neck edema Grade 1 Neck edema Asymptomatic localized neck edema NCI Asymptomatic localized neck edema CTCAE_v5 Grade 1 Neck Edema, CTCAE PT NCI Grade 1 Neck edema PT CTCAE_v5 ctcae5:C144286 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Grade 1 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C144286 Grade 1 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Grade 1 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Grade 1 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C144287 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Nervous System Disorders - Other, Specify, CTCAE Grade 1 Nervous system disorders - Other, specify 10029205 C144287 Grade 1 Nervous system disorders - Other, specify Grade 1 Nervous system disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Nervous System Disorders - Other, Specify, CTCAE PT NCI Grade 1 Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C144288 Mild pain Mild pain Grade 1 Neuralgia Grade 1 Neuralgia, CTCAE 10029223 C144288 Grade 1 Neuralgia Grade 1 Neuralgia Mild pain NCI Mild pain CTCAE_v5 Grade 1 Neuralgia PT CTCAE_v5 Grade 1 Neuralgia, CTCAE PT NCI ctcae5:C144289 <LLN-1500/mm3; <LLN-1.5 x 10e9/L <LLN-1500/mm3; <LLN-1.5 x 10e9/L Grade 1 Neutrophil Count Decreased, CTCAE Grade 1 Neutrophil count decreased 10029366 C144289 Grade 1 Neutrophil count decreased Grade 1 Neutrophil count decreased <LLN-1500/mm3; <LLN-1.5 x 10e9/L NCI <LLN-1500/mm3; <LLN-1.5 x 10e9/L CTCAE_v5 Grade 1 Neutrophil Count Decreased, CTCAE PT NCI Grade 1 Neutrophil count decreased PT CTCAE_v5 ctcae5:C144290 Symptomatic but not limiting ADL Symptomatic but not limiting ADL Grade 1 Night Blindness, CTCAE Grade 1 Night blindness 10029404 C144290 Grade 1 Night blindness Grade 1 Night blindness Symptomatic but not limiting ADL NCI Symptomatic but not limiting ADL CTCAE_v5 Grade 1 Night Blindness, CTCAE PT NCI Grade 1 Night blindness PT CTCAE_v5 ctcae5:C144291 Asymptomatic; asymmetry with slight retraction and/or thickening of the nipple areolar complex Asymptomatic; asymmetry with slight retraction and/or thickening of the nipple areolar complex Grade 1 Nipple Deformity, CTCAE Grade 1 Nipple deformity 10065823 C144291 Grade 1 Nipple deformity Grade 1 Nipple deformity Asymptomatic; asymmetry with slight retraction and/or thickening of the nipple areolar complex NCI Asymptomatic; asymmetry with slight retraction and/or thickening of the nipple areolar complex CTCAE_v5 Grade 1 Nipple Deformity, CTCAE PT NCI Grade 1 Nipple deformity PT CTCAE_v5 ctcae5:C144292 Mild pain Mild pain Grade 1 Non-Cardiac Chest Pain, CTCAE Grade 1 Non-cardiac chest pain 10062501 C144292 Grade 1 Non-cardiac chest pain Grade 1 Non-cardiac chest pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Non-Cardiac Chest Pain, CTCAE PT NCI Grade 1 Non-cardiac chest pain PT CTCAE_v5 ctcae5:C144293 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Obstruction Gastric, CTCAE Grade 1 Obstruction gastric 10029957 C144293 Grade 1 Obstruction gastric Grade 1 Obstruction gastric Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Obstruction Gastric, CTCAE PT NCI Grade 1 Obstruction gastric PT CTCAE_v5 ctcae5:C144294 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Oculomotor Nerve Disorder, CTCAE Grade 1 Oculomotor nerve disorder 10053661 C144294 Grade 1 Oculomotor nerve disorder Grade 1 Oculomotor nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Oculomotor Nerve Disorder, CTCAE PT NCI Grade 1 Oculomotor nerve disorder PT CTCAE_v5 ctcae5:C144295 Sperm concentration > 0 to < 15 million/ml Sperm concentration > 0 to < 15 million/ml Grade 1 Oligospermia Grade 1 Oligospermia, CTCAE 10030300 C144295 Grade 1 Oligospermia Grade 1 Oligospermia Sperm concentration > 0 to < 15 million/ml NCI Sperm concentration > 0 to < 15 million/ml CTCAE_v5 Grade 1 Oligospermia PT CTCAE_v5 Grade 1 Oligospermia, CTCAE PT NCI ctcae5:C144296 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Optic Nerve Disorder, CTCAE Grade 1 Optic nerve disorder 10061322 C144296 Grade 1 Optic nerve disorder Grade 1 Optic nerve disorder Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Optic Nerve Disorder, CTCAE PT NCI Grade 1 Optic nerve disorder PT CTCAE_v5 ctcae5:C144297 Asymptomatic Asymptomatic Grade 1 Oral Cavity Fistula, CTCAE Grade 1 Oral cavity fistula 10065720 C144297 Grade 1 Oral cavity fistula Grade 1 Oral cavity fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Oral Cavity Fistula, CTCAE PT NCI Grade 1 Oral cavity fistula PT CTCAE_v5 ctcae5:C144298 Mild discomfort; not interfering with oral intake Mild discomfort; not interfering with oral intake Grade 1 Oral Dysesthesia, CTCAE Grade 1 Oral dysesthesia 10054520 C144298 Grade 1 Oral dysesthesia Grade 1 Oral dysesthesia Mild discomfort; not interfering with oral intake NCI Mild discomfort; not interfering with oral intake CTCAE_v5 Grade 1 Oral Dysesthesia, CTCAE PT NCI Grade 1 Oral dysesthesia PT CTCAE_v5 ctcae5:C144301 Mild pain Mild pain Grade 1 Oropharyngeal Pain, CTCAE Grade 1 Oropharyngeal pain 10068319 C144301 Grade 1 Oropharyngeal pain Grade 1 Oropharyngeal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Oropharyngeal Pain, CTCAE PT NCI Grade 1 Oropharyngeal pain PT CTCAE_v5 ctcae5:C144302 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Osteonecrosis of Jaw, CTCAE Grade 1 Osteonecrosis of jaw 10064658 C144302 Grade 1 Osteonecrosis of jaw Grade 1 Osteonecrosis of jaw Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Osteonecrosis of Jaw, CTCAE PT NCI Grade 1 Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C144303 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Osteonecrosis Grade 1 Osteonecrosis, CTCAE 10031264 C144303 Grade 1 Osteonecrosis Grade 1 Osteonecrosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Osteonecrosis PT CTCAE_v5 Grade 1 Osteonecrosis, CTCAE PT NCI ctcae5:C144304 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Otitis Externa, CTCAE Grade 1 Otitis externa 10033072 C144304 Grade 1 Otitis externa Grade 1 Otitis externa Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Otitis Externa, CTCAE PT NCI Grade 1 Otitis externa PT CTCAE_v5 ctcae5:C144306 Asymptomatic clinical or diagnostic observations only; intervention not indicated Asymptomatic clinical or diagnostic observations only; intervention not indicated Grade 1 Ovarian Rupture, CTCAE Grade 1 Ovarian rupture 10033279 C144306 Grade 1 Ovarian rupture Grade 1 Ovarian rupture Asymptomatic clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ovarian Rupture, CTCAE PT NCI Grade 1 Ovarian rupture PT CTCAE_v5 ctcae5:C144307 Mild pain Mild pain Grade 1 Pain In Extremity, CTCAE Grade 1 Pain in extremity 10033425 C144307 Grade 1 Pain in extremity Grade 1 Pain in extremity Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pain In Extremity, CTCAE PT NCI Grade 1 Pain in extremity PT CTCAE_v5 ctcae5:C144308 Mild pain Mild pain Grade 1 Pain of Skin, CTCAE Grade 1 Pain of skin 10033474 C144308 Grade 1 Pain of skin Grade 1 Pain of skin Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pain of Skin, CTCAE PT NCI Grade 1 Pain of skin PT CTCAE_v5 ctcae5:C144309 Mild pain Mild pain Grade 1 Pain Grade 1 Pain, CTCAE 10033371 C144309 Grade 1 Pain Grade 1 Pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pain PT CTCAE_v5 Grade 1 Pain, CTCAE PT NCI ctcae5:C144310 Minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain Minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain Grade 1 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE Grade 1 Palmar-plantar erythrodysesthesia syndrome 10054524 C144310 Grade 1 Palmar-plantar erythrodysesthesia syndrome Grade 1 Palmar-plantar erythrodysesthesia syndrome Minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain NCI Minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain CTCAE_v5 Grade 1 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE PT NCI Grade 1 Palmar-plantar erythrodysesthesia syndrome PT CTCAE_v5 ctcae5:C144311 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Pancreatic Anastomotic Leak, CTCAE Grade 1 Pancreatic anastomotic leak 10050457 C144311 Grade 1 Pancreatic anastomotic leak Grade 1 Pancreatic anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Pancreatic Anastomotic Leak, CTCAE PT NCI Grade 1 Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C144312 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pancreatic Duct Stenosis, CTCAE Grade 1 Pancreatic duct stenosis 10065703 C144312 Grade 1 Pancreatic duct stenosis Grade 1 Pancreatic duct stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pancreatic Duct Stenosis, CTCAE PT NCI Grade 1 Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C144313 <LLN and asymptomatic <LLN and asymptomatic Grade 1 Pancreatic Enzymes Decreased, CTCAE Grade 1 Pancreatic enzymes decreased 10062646 C144313 Grade 1 Pancreatic enzymes decreased Grade 1 Pancreatic enzymes decreased <LLN and asymptomatic NCI <LLN and asymptomatic CTCAE_v5 Grade 1 Pancreatic Enzymes Decreased, CTCAE PT NCI Grade 1 Pancreatic enzymes decreased PT CTCAE_v5 ctcae5:C144316 Asymptomatic; no visual field deficit Asymptomatic; no visual field deficit Grade 1 Papilledema Grade 1 Papilledema, CTCAE 10033703 C144316 Grade 1 Papilledema Grade 1 Papilledema Asymptomatic; no visual field deficit NCI Asymptomatic; no visual field deficit CTCAE_v5 Grade 1 Papilledema PT CTCAE_v5 Grade 1 Papilledema, CTCAE PT NCI ctcae5:C144317 Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness Grade 1 Papulopustular Rash, CTCAE Grade 1 Papulopustular rash 10069138 C144317 Grade 1 Papulopustular rash Grade 1 Papulopustular rash Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness NCI Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness CTCAE_v5 Grade 1 Papulopustular Rash, CTCAE PT NCI Grade 1 Papulopustular rash PT CTCAE_v5 ctcae5:C144318 Mild symptoms Mild symptoms Grade 1 Paresthesia Grade 1 Paresthesia, CTCAE 10033987 C144318 Grade 1 Paresthesia Grade 1 Paresthesia Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Paresthesia PT CTCAE_v5 Grade 1 Paresthesia, CTCAE PT NCI ctcae5:C144319 Nail fold edema or erythema; disruption of the cuticle Nail fold edema or erythema; disruption of the cuticle Grade 1 Paronychia Grade 1 Paronychia, CTCAE 10034016 C144319 Grade 1 Paronychia Grade 1 Paronychia Nail fold edema or erythema; disruption of the cuticle NCI Nail fold edema or erythema; disruption of the cuticle CTCAE_v5 Grade 1 Paronychia PT CTCAE_v5 Grade 1 Paronychia, CTCAE PT NCI ctcae5:C144320 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Paroxysmal Atrial Tachycardia, CTCAE Grade 1 Paroxysmal atrial tachycardia 10034040 C144320 Grade 1 Paroxysmal atrial tachycardia Grade 1 Paroxysmal atrial tachycardia Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Grade 1 Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C144321 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pelvic Floor Muscle Weakness, CTCAE Grade 1 Pelvic floor muscle weakness 10064026 C144321 Grade 1 Pelvic floor muscle weakness Grade 1 Pelvic floor muscle weakness Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pelvic Floor Muscle Weakness, CTCAE PT NCI Grade 1 Pelvic floor muscle weakness PT CTCAE_v5 ctcae5:C144322 Mild pain Mild pain Grade 1 Pelvic Pain, CTCAE Grade 1 Pelvic pain 10034263 C144322 Grade 1 Pelvic pain Grade 1 Pelvic pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pelvic Pain, CTCAE PT NCI Grade 1 Pelvic pain PT CTCAE_v5 ctcae5:C144323 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Penile Infection, CTCAE Grade 1 Penile infection 10061912 C144323 Grade 1 Penile infection Grade 1 Penile infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Penile Infection, CTCAE PT NCI Grade 1 Penile infection PT CTCAE_v5 ctcae5:C144325 Mild pain Mild pain Grade 1 Perineal Pain, CTCAE Grade 1 Perineal pain 10061339 C144325 Grade 1 Perineal pain Grade 1 Perineal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Perineal Pain, CTCAE PT NCI Grade 1 Perineal pain PT CTCAE_v5 ctcae5:C144326 Soft or non-pitting Soft or non-pitting Grade 1 Periorbital Edema, CTCAE Grade 1 Periorbital edema 10054541 C144326 Grade 1 Periorbital edema Grade 1 Periorbital edema Soft or non-pitting NCI Soft or non-pitting CTCAE_v5 Grade 1 Periorbital Edema, CTCAE PT NCI Grade 1 Periorbital edema PT CTCAE_v5 ctcae5:C144327 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Peripheral Motor Neuropathy, CTCAE Grade 1 Peripheral motor neuropathy 10034580 C144327 Grade 1 Peripheral motor neuropathy Grade 1 Peripheral motor neuropathy Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Peripheral Motor Neuropathy, CTCAE PT NCI Grade 1 Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C144328 Asymptomatic Asymptomatic Grade 1 Peripheral Sensory Neuropathy, CTCAE Grade 1 Peripheral sensory neuropathy 10034620 C144328 Grade 1 Peripheral sensory neuropathy Grade 1 Peripheral sensory neuropathy Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Peripheral Sensory Neuropathy, CTCAE PT NCI Grade 1 Peripheral sensory neuropathy PT CTCAE_v5 ctcae5:C144329 Mild personality change Mild personality change Grade 1 Personality Change, CTCAE Grade 1 Personality change 10034719 C144329 Grade 1 Personality change Grade 1 Personality change Mild personality change NCI Mild personality change CTCAE_v5 Grade 1 Personality Change, CTCAE PT NCI Grade 1 Personality change PT CTCAE_v5 ctcae5:C144330 Mild pain Mild pain Grade 1 Phantom Pain, CTCAE Grade 1 Phantom pain 10056238 C144330 Grade 1 Phantom pain Grade 1 Phantom pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Phantom Pain, CTCAE PT NCI Grade 1 Phantom pain PT CTCAE_v5 ctcae5:C144331 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Pharyngeal Anastomotic Leak, CTCAE Grade 1 Pharyngeal anastomotic leak 10065705 C144331 Grade 1 Pharyngeal anastomotic leak Grade 1 Pharyngeal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Pharyngeal Anastomotic Leak, CTCAE PT NCI Grade 1 Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C144334 Endoscopic findings only; minimal symptoms with normal oral intake; mild pain but analgesics not indicated Endoscopic findings only; minimal symptoms with normal oral intake; mild pain but analgesics not indicated Grade 1 Pharyngeal Mucositis, CTCAE Grade 1 Pharyngeal mucositis 10065881 C144334 Grade 1 Pharyngeal mucositis Grade 1 Pharyngeal mucositis Endoscopic findings only; minimal symptoms with normal oral intake; mild pain but analgesics not indicated NCI Endoscopic findings only; minimal symptoms with normal oral intake; mild pain but analgesics not indicated CTCAE_v5 Grade 1 Pharyngeal Mucositis, CTCAE PT NCI Grade 1 Pharyngeal mucositis PT CTCAE_v5 ctcae5:C144335 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pharyngeal Stenosis, CTCAE Grade 1 Pharyngeal stenosis 10050028 C144335 Grade 1 Pharyngeal stenosis Grade 1 Pharyngeal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pharyngeal Stenosis, CTCAE PT NCI Grade 1 Pharyngeal stenosis PT CTCAE_v5 ctcae5:C144336 Mild pain Mild pain Grade 1 Pharyngolaryngeal Pain, CTCAE Grade 1 Pharyngolaryngeal pain 10034844 C144336 Grade 1 Pharyngolaryngeal pain Grade 1 Pharyngolaryngeal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pharyngolaryngeal Pain, CTCAE PT NCI Grade 1 Pharyngolaryngeal pain PT CTCAE_v5 ctcae5:C144337 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Phlebitis Infective, CTCAE Grade 1 Phlebitis infective 10056627 C144337 Grade 1 Phlebitis infective Grade 1 Phlebitis infective Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Phlebitis Infective, CTCAE PT NCI Grade 1 Phlebitis infective PT CTCAE_v5 ctcae5:C144338 <LLN-75,000/mm3; <LLN-75.0 x 10e9/L <LLN-75,000/mm3; <LLN-75.0 x 10e9/L Grade 1 Platelet Count Decreased, CTCAE Grade 1 Platelet count decreased 10035528 C144338 Grade 1 Platelet count decreased Grade 1 Platelet count decreased <LLN-75,000/mm3; <LLN-75.0 x 10e9/L NCI <LLN-75,000/mm3; <LLN-75.0 x 10e9/L CTCAE_v5 Grade 1 Platelet Count Decreased, CTCAE PT NCI Grade 1 Platelet count decreased PT CTCAE_v5 ctcae5:C144339 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pleural Effusion, CTCAE Grade 1 Pleural effusion 10035598 C144339 Grade 1 Pleural effusion Grade 1 Pleural effusion Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pleural Effusion, CTCAE PT NCI Grade 1 Pleural effusion PT CTCAE_v5 ctcae5:C144341 Mild pain Mild pain Grade 1 Pleuritic Pain, CTCAE Grade 1 Pleuritic pain 10035623 C144341 Grade 1 Pleuritic pain Grade 1 Pleuritic pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Pleuritic Pain, CTCAE PT NCI Grade 1 Pleuritic pain PT CTCAE_v5 ctcae5:C144342 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pneumonitis Grade 1 Pneumonitis, CTCAE 10035742 C144342 Grade 1 Pneumonitis Grade 1 Pneumonitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pneumonitis PT CTCAE_v5 Grade 1 Pneumonitis, CTCAE PT NCI ctcae5:C144343 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Postnasal Drip, CTCAE Grade 1 Postnasal drip 10036402 C144343 Grade 1 Postnasal drip Grade 1 Postnasal drip Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Postnasal Drip, CTCAE PT NCI Grade 1 Postnasal drip PT CTCAE_v5 ctcae5:C144344 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Postoperative Hemorrhage, CTCAE Grade 1 Postoperative hemorrhage 10055322 C144344 Grade 1 Postoperative hemorrhage Grade 1 Postoperative hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Postoperative Hemorrhage, CTCAE PT NCI Grade 1 Postoperative hemorrhage PT CTCAE_v5 ctcae5:C144345 Physical signs of puberty with no biochemical markers for females <8 years and males <9 years Physical signs of puberty with no biochemical markers for females <8 years and males <9 years Grade 1 Precocious Puberty, CTCAE Grade 1 Precocious puberty 10058084 C144345 Grade 1 Precocious puberty Grade 1 Precocious puberty Physical signs of puberty with no biochemical markers for females <8 years and males <9 years NCI Physical signs of puberty with no biochemical markers for females <8 years and males <9 years CTCAE_v5 Grade 1 Precocious Puberty, CTCAE PT NCI Grade 1 Precocious puberty PT CTCAE_v5 ctcae5:C144346 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Grade 1 Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C144346 Grade 1 Pregnancy, puerperium and perinatal conditions - Other, specify Grade 1 Pregnancy, puerperium and perinatal conditions - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Grade 1 Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C144347 Delivery of a liveborn infant at >34 to 37 weeks gestation Delivery of a liveborn infant at >34 to 37 weeks gestation Grade 1 Premature Delivery, CTCAE Grade 1 Premature delivery 10036595 C144347 Grade 1 Premature delivery Grade 1 Premature delivery Delivery of a liveborn infant at >34 to 37 weeks gestation NCI Delivery of a liveborn infant at >34 to 37 weeks gestation CTCAE_v5 Grade 1 Premature Delivery, CTCAE PT NCI Grade 1 Premature delivery PT CTCAE_v5 ctcae5:C144348 Occasional/minimal production of sputum with cough Occasional/minimal production of sputum with cough Grade 1 Productive Cough, CTCAE Grade 1 Productive cough 10036790 C144348 Grade 1 Productive cough Grade 1 Productive cough Occasional/minimal production of sputum with cough NCI Occasional/minimal production of sputum with cough CTCAE_v5 Grade 1 Productive Cough, CTCAE PT NCI Grade 1 Productive cough PT CTCAE_v5 ctcae5:C144349 Asymptomatic; reducible Asymptomatic; reducible Grade 1 Prolapse of Intestinal Stoma, CTCAE Grade 1 Prolapse of intestinal stoma 10065745 C144349 Grade 1 Prolapse of intestinal stoma Grade 1 Prolapse of intestinal stoma Asymptomatic; reducible NCI Asymptomatic; reducible CTCAE_v5 Grade 1 Prolapse of Intestinal Stoma, CTCAE PT NCI Grade 1 Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C144350 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Prolapse of Urostomy, CTCAE Grade 1 Prolapse of urostomy 10065822 C144350 Grade 1 Prolapse of urostomy Grade 1 Prolapse of urostomy Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Prolapse of Urostomy, CTCAE PT NCI Grade 1 Prolapse of urostomy PT CTCAE_v5 ctcae5:C144352 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Prostatic Obstruction, CTCAE Grade 1 Prostatic obstruction 10055026 C144352 Grade 1 Prostatic obstruction Grade 1 Prostatic obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Prostatic Obstruction, CTCAE PT NCI Grade 1 Prostatic obstruction PT CTCAE_v5 ctcae5:C144353 Mild pain Mild pain Grade 1 Prostatic Pain, CTCAE Grade 1 Prostatic pain 10036968 C144353 Grade 1 Prostatic pain Grade 1 Prostatic pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Prostatic Pain, CTCAE PT NCI Grade 1 Prostatic pain PT CTCAE_v5 ctcae5:C144354 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Psychiatric Disorders - Other, Specify, CTCAE Grade 1 Psychiatric disorders - Other, specify 10037175 C144354 Grade 1 Psychiatric disorders - Other, specify Grade 1 Psychiatric disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Psychiatric Disorders - Other, Specify, CTCAE PT NCI Grade 1 Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C144355 Mild psychotic symptoms Mild psychotic symptoms Grade 1 Psychosis Grade 1 Psychosis, CTCAE 10037234 C144355 Grade 1 Psychosis Grade 1 Psychosis Mild psychotic symptoms NCI Mild psychotic symptoms CTCAE_v5 Grade 1 Psychosis PT CTCAE_v5 Grade 1 Psychosis, CTCAE PT NCI ctcae5:C144356 Radiologic findings only; minimal dyspnea on exertion Radiologic findings only; minimal dyspnea on exertion Grade 1 Pulmonary Edema, CTCAE Grade 1 Pulmonary edema 10037375 C144356 Grade 1 Pulmonary edema Grade 1 Pulmonary edema Radiologic findings only; minimal dyspnea on exertion NCI Radiologic findings only; minimal dyspnea on exertion CTCAE_v5 Grade 1 Pulmonary Edema, CTCAE PT NCI Grade 1 Pulmonary edema PT CTCAE_v5 ctcae5:C144357 Radiologic pulmonary fibrosis <25% of lung volume associated with hypoxia Radiologic pulmonary fibrosis <25% of lung volume associated with hypoxia Grade 1 Pulmonary Fibrosis, CTCAE Grade 1 Pulmonary fibrosis 10037383 C144357 Grade 1 Pulmonary fibrosis Grade 1 Pulmonary fibrosis Radiologic pulmonary fibrosis <25% of lung volume associated with hypoxia NCI Radiologic pulmonary fibrosis <25% of lung volume associated with hypoxia CTCAE_v5 Grade 1 Pulmonary Fibrosis, CTCAE PT NCI Grade 1 Pulmonary fibrosis PT CTCAE_v5 ctcae5:C144358 Asymptomatic Asymptomatic Grade 1 Pulmonary Fistula, CTCAE Grade 1 Pulmonary fistula 10065873 C144358 Grade 1 Pulmonary fistula Grade 1 Pulmonary fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Pulmonary Fistula, CTCAE PT NCI Grade 1 Pulmonary fistula PT CTCAE_v5 ctcae5:C144359 Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging Grade 1 Pulmonary Valve Disease, CTCAE Grade 1 Pulmonary valve disease 10061541 C144359 Grade 1 Pulmonary valve disease Grade 1 Pulmonary valve disease Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging NCI Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis by imaging CTCAE_v5 Grade 1 Pulmonary Valve Disease, CTCAE PT NCI Grade 1 Pulmonary valve disease PT CTCAE_v5 ctcae5:C144360 Combined area of lesions covering <10% BSA Combined area of lesions covering <10% BSA Grade 1 Purpura Grade 1 Purpura, CTCAE 10037549 C144360 Grade 1 Purpura Grade 1 Purpura Combined area of lesions covering <10% BSA NCI Combined area of lesions covering <10% BSA CTCAE_v5 Grade 1 Purpura PT CTCAE_v5 Grade 1 Purpura, CTCAE PT NCI ctcae5:C144361 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pyramidal Tract Syndrome, CTCAE Grade 1 Pyramidal tract syndrome 10063636 C144361 Grade 1 Pyramidal tract syndrome Grade 1 Pyramidal tract syndrome Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pyramidal Tract Syndrome, CTCAE PT NCI Grade 1 Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C144362 Faint erythema or dry desquamation Faint erythema or dry desquamation Grade 1 Radiation Recall Reaction (Dermatologic), CTCAE Grade 1 Radiation recall reaction (dermatologic) 10037767 C144362 Grade 1 Radiation recall reaction (dermatologic) Grade 1 Radiation recall reaction (dermatologic) Faint erythema or dry desquamation NCI Faint erythema or dry desquamation CTCAE_v5 Grade 1 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Grade 1 Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C144363 Mild symptoms Mild symptoms Grade 1 Radiculitis Grade 1 Radiculitis, CTCAE 10061928 C144363 Grade 1 Radiculitis Grade 1 Radiculitis Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Radiculitis PT CTCAE_v5 Grade 1 Radiculitis, CTCAE PT NCI ctcae5:C144364 Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness Grade 1 Rash Acneiform, CTCAE Grade 1 Rash acneiform 10037847 C144364 Grade 1 Rash acneiform Grade 1 Rash acneiform Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness NCI Papules and/or pustules covering <10% BSA, which may or may not be associated with symptoms of pruritus or tenderness CTCAE_v5 Grade 1 Rash Acneiform, CTCAE PT NCI Grade 1 Rash acneiform PT CTCAE_v5 ctcae5:C144365 Macules/papules covering <10% BSA with or without symptoms (e.g., pruritus, burning, tightness) Macules/papules covering <10% BSA with or without symptoms (e.g., pruritus, burning, tightness) Grade 1 Rash Maculo-Papular, CTCAE Grade 1 Rash maculo-papular 10037868 C144365 Grade 1 Rash maculo-papular Grade 1 Rash maculo-papular Macules/papules covering <10% BSA with or without symptoms (e.g., pruritus, burning, tightness) NCI Macules/papules covering <10% BSA with or without symptoms (e.g., pruritus, burning, tightness) CTCAE_v5 Grade 1 Rash Maculo-Papular, CTCAE PT NCI Grade 1 Rash maculo-papular PT CTCAE_v5 ctcae5:C144366 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Rectal Anastomotic Leak, CTCAE Grade 1 Rectal anastomotic leak 10065894 C144366 Grade 1 Rectal anastomotic leak Grade 1 Rectal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Rectal Anastomotic Leak, CTCAE PT NCI Grade 1 Rectal anastomotic leak PT CTCAE_v5 ctcae5:C144367 Asymptomatic Asymptomatic Grade 1 Rectal Fissure, CTCAE Grade 1 Rectal fissure 10064993 C144367 Grade 1 Rectal fissure Grade 1 Rectal fissure Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Rectal Fissure, CTCAE PT NCI Grade 1 Rectal fissure PT CTCAE_v5 ctcae5:C144370 Asymptomatic or mild symptoms; intervention not indicated Asymptomatic or mild symptoms; intervention not indicated Grade 1 Rectal Mucositis, CTCAE Grade 1 Rectal mucositis 10063190 C144370 Grade 1 Rectal mucositis Grade 1 Rectal mucositis Asymptomatic or mild symptoms; intervention not indicated NCI Asymptomatic or mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Rectal Mucositis, CTCAE PT NCI Grade 1 Rectal mucositis PT CTCAE_v5 ctcae5:C144372 Mild pain Mild pain Grade 1 Rectal Pain, CTCAE Grade 1 Rectal pain 10038072 C144372 Grade 1 Rectal pain Grade 1 Rectal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Rectal Pain, CTCAE PT NCI Grade 1 Rectal pain PT CTCAE_v5 ctcae5:C144373 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Rectal Stenosis, CTCAE Grade 1 Rectal stenosis 10038079 C144373 Grade 1 Rectal stenosis Grade 1 Rectal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Rectal Stenosis, CTCAE PT NCI Grade 1 Rectal stenosis PT CTCAE_v5 ctcae5:C144375 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Recurrent Laryngeal Nerve Palsy, CTCAE Grade 1 Recurrent laryngeal nerve palsy 10038130 C144375 Grade 1 Recurrent laryngeal nerve palsy Grade 1 Recurrent laryngeal nerve palsy Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Grade 1 Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C144376 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Renal and Urinary Disorders - Other, Specify, CTCAE Grade 1 Renal and urinary disorders - Other, specify 10038359 C144376 Grade 1 Renal and urinary disorders - Other, specify Grade 1 Renal and urinary disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Grade 1 Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C144377 Asymptomatic or mild symptoms; occasional use of nonprescription analgesics indicated Asymptomatic or mild symptoms; occasional use of nonprescription analgesics indicated Grade 1 Renal Calculi, CTCAE Grade 1 Renal calculi 10038385 C144377 Grade 1 Renal calculi Grade 1 Renal calculi Asymptomatic or mild symptoms; occasional use of nonprescription analgesics indicated NCI Asymptomatic or mild symptoms; occasional use of nonprescription analgesics indicated CTCAE_v5 Grade 1 Renal Calculi, CTCAE PT NCI Grade 1 Renal calculi PT CTCAE_v5 ctcae5:C144378 Mild pain not interfering with activity; nonprescription medication indicated Mild pain not interfering with activity; nonprescription medication indicated Grade 1 Renal Colic, CTCAE Grade 1 Renal colic 10038419 C144378 Grade 1 Renal colic Grade 1 Renal colic Mild pain not interfering with activity; nonprescription medication indicated NCI Mild pain not interfering with activity; nonprescription medication indicated CTCAE_v5 Grade 1 Renal Colic, CTCAE PT NCI Grade 1 Renal colic PT CTCAE_v5 ctcae5:C144380 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Reproductive System and Breast Disorders - Other, Specify, CTCAE Grade 1 Reproductive system and breast disorders - Other, specify 10038604 C144380 Grade 1 Reproductive system and breast disorders - Other, specify Grade 1 Reproductive system and breast disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Grade 1 Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C144381 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Grade 1 Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C144381 Grade 1 Respiratory, thoracic and mediastinal disorders - Other, specify Grade 1 Respiratory, thoracic and mediastinal disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Grade 1 Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C144382 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Restlessness Grade 1 Restlessness, CTCAE 10038743 C144382 Grade 1 Restlessness Grade 1 Restlessness Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Restlessness PT CTCAE_v5 Grade 1 Restlessness, CTCAE PT NCI ctcae5:C144383 No retinal detachment and treatment not indicated No retinal detachment and treatment not indicated Grade 1 Retinal Tear, CTCAE Grade 1 Retinal tear 10038897 C144383 Grade 1 Retinal tear Grade 1 Retinal tear No retinal detachment and treatment not indicated NCI No retinal detachment and treatment not indicated CTCAE_v5 Grade 1 Retinal Tear, CTCAE PT NCI Grade 1 Retinal tear PT CTCAE_v5 ctcae5:C144384 Asymptomatic, intervention not indicated; laboratory findings only Asymptomatic, intervention not indicated; laboratory findings only Grade 1 Rhabdomyolysis Grade 1 Rhabdomyolysis, CTCAE 10039020 C144384 Grade 1 Rhabdomyolysis Grade 1 Rhabdomyolysis Asymptomatic, intervention not indicated; laboratory findings only NCI Asymptomatic, intervention not indicated; laboratory findings only CTCAE_v5 Grade 1 Rhabdomyolysis PT CTCAE_v5 Grade 1 Rhabdomyolysis, CTCAE PT NCI ctcae5:C144385 Present Present Grade 1 Rhinorrhea Grade 1 Rhinorrhea, CTCAE 10039100 C144385 Grade 1 Rhinorrhea Grade 1 Rhinorrhea Present NCI Present CTCAE_v5 Grade 1 Rhinorrhea PT CTCAE_v5 Grade 1 Rhinorrhea, CTCAE PT NCI ctcae5:C144386 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Rotator Cuff Injury, CTCAE Grade 1 Rotator cuff injury 10039226 C144386 Grade 1 Rotator cuff injury Grade 1 Rotator cuff injury Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Rotator Cuff Injury, CTCAE PT NCI Grade 1 Rotator cuff injury PT CTCAE_v5 ctcae5:C144387 Slightly thickened saliva; slightly altered taste (e.g., metallic) Slightly thickened saliva; slightly altered taste (e.g., metallic) Grade 1 Salivary Duct Inflammation, CTCAE Grade 1 Salivary duct inflammation 10056681 C144387 Grade 1 Salivary duct inflammation Grade 1 Salivary duct inflammation Slightly thickened saliva; slightly altered taste (e.g., metallic) NCI Slightly thickened saliva; slightly altered taste (e.g., metallic) CTCAE_v5 Grade 1 Salivary Duct Inflammation, CTCAE PT NCI Grade 1 Salivary duct inflammation PT CTCAE_v5 ctcae5:C144388 No change in vision from baseline No change in vision from baseline Grade 1 Scleral Disorder, CTCAE Grade 1 Scleral disorder 10061510 C144388 Grade 1 Scleral disorder Grade 1 Scleral disorder No change in vision from baseline NCI No change in vision from baseline CTCAE_v5 Grade 1 Scleral Disorder, CTCAE PT NCI Grade 1 Scleral disorder PT CTCAE_v5 ctcae5:C144389 <20 degrees; clinically undetectable <20 degrees; clinically undetectable Grade 1 Scoliosis Grade 1 Scoliosis, CTCAE 10039722 C144389 Grade 1 Scoliosis Grade 1 Scoliosis <20 degrees; clinically undetectable NCI <20 degrees; clinically undetectable CTCAE_v5 Grade 1 Scoliosis PT CTCAE_v5 Grade 1 Scoliosis, CTCAE PT NCI ctcae5:C144390 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Scrotal Infection, CTCAE Grade 1 Scrotal infection 10062156 C144390 Grade 1 Scrotal infection Grade 1 Scrotal infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Scrotal Infection, CTCAE PT NCI Grade 1 Scrotal infection PT CTCAE_v5 ctcae5:C144391 Mild pain Mild pain Grade 1 Scrotal Pain, CTCAE Grade 1 Scrotal pain 10039757 C144391 Grade 1 Scrotal pain Grade 1 Scrotal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Scrotal Pain, CTCAE PT NCI Grade 1 Scrotal pain PT CTCAE_v5 ctcae5:C144392 Brief partial seizure and no loss of consciousness Brief partial seizure and no loss of consciousness Grade 1 Seizure Grade 1 Seizure, CTCAE 10039906 C144392 Grade 1 Seizure Grade 1 Seizure Brief partial seizure and no loss of consciousness NCI Brief partial seizure and no loss of consciousness CTCAE_v5 Grade 1 Seizure PT CTCAE_v5 Grade 1 Seizure, CTCAE PT NCI ctcae5:C144393 >ULN-1.5 x ULN >ULN-1.5 x ULN Grade 1 Serum Amylase Increased, CTCAE Grade 1 Serum amylase increased 10040139 C144393 Grade 1 Serum amylase increased Grade 1 Serum amylase increased >ULN-1.5 x ULN NCI >ULN-1.5 x ULN CTCAE_v5 Grade 1 Serum Amylase Increased, CTCAE PT NCI Grade 1 Serum amylase increased PT CTCAE_v5 ctcae5:C144394 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Serum Sickness, CTCAE Grade 1 Serum sickness 10040400 C144394 Grade 1 Serum sickness Grade 1 Serum sickness Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Serum Sickness, CTCAE PT NCI Grade 1 Serum sickness PT CTCAE_v5 ctcae5:C144395 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Shingles Grade 1 Shingles, CTCAE 10040555 C144395 Grade 1 Shingles Grade 1 Shingles Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Shingles PT CTCAE_v5 Grade 1 Shingles, CTCAE PT NCI ctcae5:C144396 Asymptomatic mucosal crusting; blood-tinged secretions Asymptomatic mucosal crusting; blood-tinged secretions Grade 1 Sinus Disorder, CTCAE Grade 1 Sinus disorder 10062244 C144396 Grade 1 Sinus disorder Grade 1 Sinus disorder Asymptomatic mucosal crusting; blood-tinged secretions NCI Asymptomatic mucosal crusting; blood-tinged secretions CTCAE_v5 Grade 1 Sinus Disorder, CTCAE PT NCI Grade 1 Sinus disorder PT CTCAE_v5 ctcae5:C144397 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Grade 1 Skin and subcutaneous tissue disorders - Other, specify 10040785 C144397 Grade 1 Skin and subcutaneous tissue disorders - Other, specify Grade 1 Skin and subcutaneous tissue disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Grade 1 Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C144398 Hyperpigmentation covering <10% BSA; no psychosocial impact Hyperpigmentation covering <10% BSA; no psychosocial impact Grade 1 Skin Hyperpigmentation, CTCAE Grade 1 Skin hyperpigmentation 10040865 C144398 Grade 1 Skin hyperpigmentation Grade 1 Skin hyperpigmentation Hyperpigmentation covering <10% BSA; no psychosocial impact NCI Hyperpigmentation covering <10% BSA; no psychosocial impact CTCAE_v5 Grade 1 Skin Hyperpigmentation, CTCAE PT NCI Grade 1 Skin hyperpigmentation PT CTCAE_v5 ctcae5:C144399 Hypopigmentation or depigmentation covering <10% BSA; no psychosocial impact Hypopigmentation or depigmentation covering <10% BSA; no psychosocial impact Grade 1 Skin Hypopigmentation, CTCAE Grade 1 Skin hypopigmentation 10040868 C144399 Grade 1 Skin hypopigmentation Grade 1 Skin hypopigmentation Hypopigmentation or depigmentation covering <10% BSA; no psychosocial impact NCI Hypopigmentation or depigmentation covering <10% BSA; no psychosocial impact CTCAE_v5 Grade 1 Skin Hypopigmentation, CTCAE PT NCI Grade 1 Skin hypopigmentation PT CTCAE_v5 ctcae5:C144400 Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Grade 1 Skin Induration, CTCAE Grade 1 Skin induration 10051837 C144400 Grade 1 Skin induration Grade 1 Skin induration Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) NCI Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) CTCAE_v5 Grade 1 Skin Induration, CTCAE PT NCI Grade 1 Skin induration PT CTCAE_v5 ctcae5:C144401 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Skin Infection, CTCAE Grade 1 Skin infection 10040872 C144401 Grade 1 Skin infection Grade 1 Skin infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Skin Infection, CTCAE PT NCI Grade 1 Skin infection PT CTCAE_v5 ctcae5:C144402 Asymptomatic; intervention not indicated Asymptomatic; intervention not indicated Grade 1 Skin Papilloma, CTCAE Grade 1 Skin papilloma 10040907 C144402 Grade 1 Skin papilloma Grade 1 Skin papilloma Asymptomatic; intervention not indicated NCI Asymptomatic; intervention not indicated CTCAE_v5 Grade 1 Skin Papilloma, CTCAE PT NCI Grade 1 Skin papilloma PT CTCAE_v5 ctcae5:C144403 Combined area of ulcers <1 cm; nonblanchable erythema of intact skin with associated warmth or edema Combined area of ulcers <1 cm; nonblanchable erythema of intact skin with associated warmth or edema Grade 1 Skin Ulceration, CTCAE Grade 1 Skin ulceration 10040947 C144403 Grade 1 Skin ulceration Grade 1 Skin ulceration Combined area of ulcers <1 cm; nonblanchable erythema of intact skin with associated warmth or edema NCI Combined area of ulcers <1 cm; nonblanchable erythema of intact skin with associated warmth or edema CTCAE_v5 Grade 1 Skin Ulceration, CTCAE PT NCI Grade 1 Skin ulceration PT CTCAE_v5 ctcae5:C144404 Snoring and nocturnal sleep arousal without apneic periods Snoring and nocturnal sleep arousal without apneic periods Grade 1 Sleep Apnea, CTCAE Grade 1 Sleep apnea 10040975 C144404 Grade 1 Sleep apnea Grade 1 Sleep apnea Snoring and nocturnal sleep arousal without apneic periods NCI Snoring and nocturnal sleep arousal without apneic periods CTCAE_v5 Grade 1 Sleep Apnea, CTCAE PT NCI Grade 1 Sleep apnea PT CTCAE_v5 ctcae5:C144405 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Small Intestinal Anastomotic Leak, CTCAE Grade 1 Small intestinal anastomotic leak 10065892 C144405 Grade 1 Small intestinal anastomotic leak Grade 1 Small intestinal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Small Intestinal Anastomotic Leak, CTCAE PT NCI Grade 1 Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C144406 Asymptomatic or mild symptoms; intervention not indicated Asymptomatic or mild symptoms; intervention not indicated Grade 1 Small Intestinal Mucositis, CTCAE Grade 1 Small intestinal mucositis 10065710 C144406 Grade 1 Small intestinal mucositis Grade 1 Small intestinal mucositis Asymptomatic or mild symptoms; intervention not indicated NCI Asymptomatic or mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Small Intestinal Mucositis, CTCAE PT NCI Grade 1 Small intestinal mucositis PT CTCAE_v5 ctcae5:C144407 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Small Intestinal Obstruction, CTCAE Grade 1 Small intestinal obstruction 10041101 C144407 Grade 1 Small intestinal obstruction Grade 1 Small intestinal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Small Intestinal Obstruction, CTCAE PT NCI Grade 1 Small intestinal obstruction PT CTCAE_v5 ctcae5:C144408 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Small Intestinal Stenosis, CTCAE Grade 1 Small intestinal stenosis 10062263 C144408 Grade 1 Small intestinal stenosis Grade 1 Small intestinal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Small Intestinal Stenosis, CTCAE PT NCI Grade 1 Small intestinal stenosis PT CTCAE_v5 ctcae5:C144409 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Small Intestine Ulcer, CTCAE Grade 1 Small intestine ulcer 10041133 C144409 Grade 1 Small intestine ulcer Grade 1 Small intestine ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Small Intestine Ulcer, CTCAE PT NCI Grade 1 Small intestine ulcer PT CTCAE_v5 ctcae5:C144410 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Sneezing Grade 1 Sneezing, CTCAE 10041232 C144410 Grade 1 Sneezing Grade 1 Sneezing Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Sneezing PT CTCAE_v5 Grade 1 Sneezing, CTCAE PT NCI ctcae5:C144411 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Social Circumstances - Other, Specify, CTCAE Grade 1 Social circumstances - Other, specify 10041244 C144411 Grade 1 Social circumstances - Other, specify Grade 1 Social circumstances - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Social Circumstances - Other, Specify, CTCAE PT NCI Grade 1 Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C144412 Mild but more than usual drowsiness or sleepiness Mild but more than usual drowsiness or sleepiness Grade 1 Somnolence Grade 1 Somnolence, CTCAE 10041349 C144412 Grade 1 Somnolence Grade 1 Somnolence Mild but more than usual drowsiness or sleepiness NCI Mild but more than usual drowsiness or sleepiness CTCAE_v5 Grade 1 Somnolence PT CTCAE_v5 Grade 1 Somnolence, CTCAE PT NCI ctcae5:C144413 Mild pain Mild pain Grade 1 Sore Throat, CTCAE Grade 1 Sore throat 10041367 C144413 Grade 1 Sore throat Grade 1 Sore throat Mild pain NCI Mild pain CTCAE_v5 Grade 1 Sore Throat, CTCAE PT NCI Grade 1 Sore throat PT CTCAE_v5 ctcae5:C144414 Mild or slight increase in muscle tone Mild or slight increase in muscle tone Grade 1 Spasticity Grade 1 Spasticity, CTCAE 10041416 C144414 Grade 1 Spasticity Grade 1 Spasticity Mild or slight increase in muscle tone NCI Mild or slight increase in muscle tone CTCAE_v5 Grade 1 Spasticity PT CTCAE_v5 Grade 1 Spasticity, CTCAE PT NCI ctcae5:C144415 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Spermatic Cord Anastomotic Leak, CTCAE Grade 1 Spermatic cord anastomotic leak 10065897 C144415 Grade 1 Spermatic cord anastomotic leak Grade 1 Spermatic cord anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Grade 1 Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C144416 Mild back pain; nonprescription analgesics indicated Mild back pain; nonprescription analgesics indicated Grade 1 Spinal Fracture, CTCAE Grade 1 Spinal fracture 10041569 C144416 Grade 1 Spinal fracture Grade 1 Spinal fracture Mild back pain; nonprescription analgesics indicated NCI Mild back pain; nonprescription analgesics indicated CTCAE_v5 Grade 1 Spinal Fracture, CTCAE PT NCI Grade 1 Spinal fracture PT CTCAE_v5 ctcae5:C144417 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Stoma Site Infection, CTCAE Grade 1 Stoma site infection 10064505 C144417 Grade 1 Stoma site infection Grade 1 Stoma site infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Stoma Site Infection, CTCAE PT NCI Grade 1 Stoma site infection PT CTCAE_v5 ctcae5:C144418 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Stomal Ulcer, CTCAE Grade 1 Stomal ulcer 10042127 C144418 Grade 1 Stomal ulcer Grade 1 Stomal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Stomal Ulcer, CTCAE PT NCI Grade 1 Stomal ulcer PT CTCAE_v5 ctcae5:C144419 Incidental radiographic findings only Incidental radiographic findings only Grade 1 Stroke Grade 1 Stroke, CTCAE 10042244 C144419 Grade 1 Stroke Grade 1 Stroke Incidental radiographic findings only NCI Incidental radiographic findings only CTCAE_v5 Grade 1 Stroke PT CTCAE_v5 Grade 1 Stroke, CTCAE PT NCI ctcae5:C144420 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Subcutaneous Emphysema, CTCAE Grade 1 Subcutaneous emphysema 10042344 C144420 Grade 1 Subcutaneous emphysema Grade 1 Subcutaneous emphysema Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Subcutaneous Emphysema, CTCAE PT NCI Grade 1 Subcutaneous emphysema PT CTCAE_v5 ctcae5:C144421 Increased thoughts of death but no wish to kill oneself Increased thoughts of death but no wish to kill oneself Grade 1 Suicidal Ideation, CTCAE Grade 1 Suicidal ideation 10042458 C144421 Grade 1 Suicidal ideation Grade 1 Suicidal ideation Increased thoughts of death but no wish to kill oneself NCI Increased thoughts of death but no wish to kill oneself CTCAE_v5 Grade 1 Suicidal Ideation, CTCAE PT NCI Grade 1 Suicidal ideation PT CTCAE_v5 ctcae5:C144422 Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) Grade 1 Superficial Soft Tissue Fibrosis, CTCAE Grade 1 Superficial soft tissue fibrosis 10065798 C144422 Grade 1 Superficial soft tissue fibrosis Grade 1 Superficial soft tissue fibrosis Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) NCI Mild induration, able to move skin parallel to plane (sliding) and perpendicular to skin (pinching up) CTCAE_v5 Grade 1 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Grade 1 Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C144423 Asymptomatic; incidental finding of SVC thrombosis Asymptomatic; incidental finding of SVC thrombosis Grade 1 Superior Vena Cava Syndrome, CTCAE Grade 1 Superior vena cava syndrome 10042569 C144423 Grade 1 Superior vena cava syndrome Grade 1 Superior vena cava syndrome Asymptomatic; incidental finding of SVC thrombosis NCI Asymptomatic; incidental finding of SVC thrombosis CTCAE_v5 Grade 1 Superior Vena Cava Syndrome, CTCAE PT NCI Grade 1 Superior vena cava syndrome PT CTCAE_v5 ctcae5:C144424 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Surgical and Medical Procedures - Other, Specify, CTCAE Grade 1 Surgical and medical procedures - Other, specify 10042613 C144424 Grade 1 Surgical and medical procedures - Other, specify Grade 1 Surgical and medical procedures - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Grade 1 Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C144425 Ankle reflex reduced Ankle reflex reduced Grade 1 Tendon Reflex Decreased, CTCAE Grade 1 Tendon reflex decreased 10043245 C144425 Grade 1 Tendon reflex decreased Grade 1 Tendon reflex decreased Ankle reflex reduced NCI Ankle reflex reduced CTCAE_v5 Grade 1 Tendon Reflex Decreased, CTCAE PT NCI Grade 1 Tendon reflex decreased PT CTCAE_v5 ctcae5:C144426 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Testicular Disorder, CTCAE Grade 1 Testicular disorder 10043306 C144426 Grade 1 Testicular disorder Grade 1 Testicular disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Testicular Disorder, CTCAE PT NCI Grade 1 Testicular disorder PT CTCAE_v5 ctcae5:C144428 Mild pain Mild pain Grade 1 Testicular Pain, CTCAE Grade 1 Testicular pain 10043345 C144428 Grade 1 Testicular pain Grade 1 Testicular pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Testicular Pain, CTCAE PT NCI Grade 1 Testicular pain PT CTCAE_v5 ctcae5:C144429 Asymptomatic; mild symptoms with no intervention indicated Asymptomatic; mild symptoms with no intervention indicated Grade 1 Testosterone Deficiency, CTCAE Grade 1 Testosterone deficiency 10067734 C144429 Grade 1 Testosterone deficiency Grade 1 Testosterone deficiency Asymptomatic; mild symptoms with no intervention indicated NCI Asymptomatic; mild symptoms with no intervention indicated CTCAE_v5 Grade 1 Testosterone Deficiency, CTCAE PT NCI Grade 1 Testosterone deficiency PT CTCAE_v5 ctcae5:C144430 Medical intervention not indicated (e.g., superficial thrombosis) Medical intervention not indicated (e.g., superficial thrombosis) Grade 1 Thromboembolic Event, CTCAE Grade 1 Thromboembolic event 10043565 C144430 Grade 1 Thromboembolic event Grade 1 Thromboembolic event Medical intervention not indicated (e.g., superficial thrombosis) NCI Medical intervention not indicated (e.g., superficial thrombosis) CTCAE_v5 Grade 1 Thromboembolic Event, CTCAE PT NCI Grade 1 Thromboembolic event PT CTCAE_v5 ctcae5:C144431 Asymptomatic; local symptomatic management Asymptomatic; local symptomatic management Grade 1 Thrush Grade 1 Thrush, CTCAE 10043649 C144431 Grade 1 Thrush Grade 1 Thrush Asymptomatic; local symptomatic management NCI Asymptomatic; local symptomatic management CTCAE_v5 Grade 1 Thrush PT CTCAE_v5 Grade 1 Thrush, CTCAE PT NCI ctcae5:C144432 TSH increased and no intervention initiated TSH increased and no intervention initiated Grade 1 Thyroid Stimulating Hormone Increased, CTCAE Grade 1 Thyroid stimulating hormone increased 10043770 C144432 Grade 1 Thyroid stimulating hormone increased Grade 1 Thyroid stimulating hormone increased TSH increased and no intervention initiated NCI TSH increased and no intervention initiated CTCAE_v5 Grade 1 Thyroid Stimulating Hormone Increased, CTCAE PT NCI Grade 1 Thyroid stimulating hormone increased PT CTCAE_v5 ctcae5:C144433 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Tinnitus Grade 1 Tinnitus, CTCAE 10043882 C144433 Grade 1 Tinnitus Grade 1 Tinnitus Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Tinnitus PT CTCAE_v5 Grade 1 Tinnitus, CTCAE PT NCI ctcae5:C144434 Asymptomatic; hypoplasia of tooth or enamel Asymptomatic; hypoplasia of tooth or enamel Grade 1 Tooth Development Disorder, CTCAE Grade 1 Tooth development disorder 10044030 C144434 Grade 1 Tooth development disorder Grade 1 Tooth development disorder Asymptomatic; hypoplasia of tooth or enamel NCI Asymptomatic; hypoplasia of tooth or enamel CTCAE_v5 Grade 1 Tooth Development Disorder, CTCAE PT NCI Grade 1 Tooth development disorder PT CTCAE_v5 ctcae5:C144435 Surface stains Surface stains Grade 1 Tooth Discoloration, CTCAE Grade 1 Tooth discoloration 10044031 C144435 Grade 1 Tooth discoloration Grade 1 Tooth discoloration Surface stains NCI Surface stains CTCAE_v5 Grade 1 Tooth Discoloration, CTCAE PT NCI Grade 1 Tooth discoloration PT CTCAE_v5 ctcae5:C144436 Mild pain Mild pain Grade 1 Toothache Grade 1 Toothache, CTCAE 10044055 C144436 Grade 1 Toothache Grade 1 Toothache Mild pain NCI Mild pain CTCAE_v5 Grade 1 Toothache PT CTCAE_v5 Grade 1 Toothache, CTCAE PT NCI ctcae5:C144439 Endoscopic findings only; minimal hemoptysis, pain, or respiratory symptoms Endoscopic findings only; minimal hemoptysis, pain, or respiratory symptoms Grade 1 Tracheal Mucositis, CTCAE Grade 1 Tracheal mucositis 10065900 C144439 Grade 1 Tracheal mucositis Grade 1 Tracheal mucositis Endoscopic findings only; minimal hemoptysis, pain, or respiratory symptoms NCI Endoscopic findings only; minimal hemoptysis, pain, or respiratory symptoms CTCAE_v5 Grade 1 Tracheal Mucositis, CTCAE PT NCI Grade 1 Tracheal mucositis PT CTCAE_v5 ctcae5:C144440 Partial asymptomatic obstruction on examination (e.g., visual, radiologic or endoscopic) Partial asymptomatic obstruction on examination (e.g., visual, radiologic or endoscopic) Grade 1 Tracheal Obstruction, CTCAE Grade 1 Tracheal obstruction 10044291 C144440 Grade 1 Tracheal obstruction Grade 1 Tracheal obstruction Partial asymptomatic obstruction on examination (e.g., visual, radiologic or endoscopic) NCI Partial asymptomatic obstruction on examination (e.g., visual, radiologic or endoscopic) CTCAE_v5 Grade 1 Tracheal Obstruction, CTCAE PT NCI Grade 1 Tracheal obstruction PT CTCAE_v5 ctcae5:C144441 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Tracheal Stenosis, CTCAE Grade 1 Tracheal stenosis 10050816 C144441 Grade 1 Tracheal stenosis Grade 1 Tracheal stenosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Tracheal Stenosis, CTCAE PT NCI Grade 1 Tracheal stenosis PT CTCAE_v5 ctcae5:C144442 Minimal bleeding identified on clinical exam; intervention not indicated Minimal bleeding identified on clinical exam; intervention not indicated Grade 1 Tracheostomy Site Bleeding, CTCAE Grade 1 Tracheostomy site bleeding 10065749 C144442 Grade 1 Tracheostomy site bleeding Grade 1 Tracheostomy site bleeding Minimal bleeding identified on clinical exam; intervention not indicated NCI Minimal bleeding identified on clinical exam; intervention not indicated CTCAE_v5 Grade 1 Tracheostomy Site Bleeding, CTCAE PT NCI Grade 1 Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C144443 Mild neurologic deficit with or without imaging confirmation Mild neurologic deficit with or without imaging confirmation Grade 1 Transient Ischemic Attacks, CTCAE Grade 1 Transient ischemic attacks 10044391 C144443 Grade 1 Transient ischemic attacks Grade 1 Transient ischemic attacks Mild neurologic deficit with or without imaging confirmation NCI Mild neurologic deficit with or without imaging confirmation CTCAE_v5 Grade 1 Transient Ischemic Attacks, CTCAE PT NCI Grade 1 Transient ischemic attacks PT CTCAE_v5 ctcae5:C144444 Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis Grade 1 Tricuspid Valve Disease, CTCAE Grade 1 Tricuspid valve disease 10061389 C144444 Grade 1 Tricuspid valve disease Grade 1 Tricuspid valve disease Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis NCI Asymptomatic valvular thickening with or without mild valvular regurgitation or stenosis CTCAE_v5 Grade 1 Tricuspid Valve Disease, CTCAE PT NCI Grade 1 Tricuspid valve disease PT CTCAE_v5 ctcae5:C144445 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Trigeminal Nerve Disorder, CTCAE Grade 1 Trigeminal nerve disorder 10060890 C144445 Grade 1 Trigeminal nerve disorder Grade 1 Trigeminal nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Trigeminal Nerve Disorder, CTCAE PT NCI Grade 1 Trigeminal nerve disorder PT CTCAE_v5 ctcae5:C144446 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Trochlear Nerve Disorder, CTCAE Grade 1 Trochlear nerve disorder 10074765 C144446 Grade 1 Trochlear nerve disorder Grade 1 Trochlear nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Trochlear Nerve Disorder, CTCAE PT NCI Grade 1 Trochlear nerve disorder PT CTCAE_v5 ctcae5:C144447 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Tumor Hemorrhage, CTCAE Grade 1 Tumor hemorrhage 10055351 C144447 Grade 1 Tumor hemorrhage Grade 1 Tumor hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Tumor Hemorrhage, CTCAE PT NCI Grade 1 Tumor hemorrhage PT CTCAE_v5 ctcae5:C144448 Mild length discrepancy <2 cm Mild length discrepancy <2 cm Grade 1 Unequal Limb Length, CTCAE Grade 1 Unequal limb length 10065738 C144448 Grade 1 Unequal limb length Grade 1 Unequal limb length Mild length discrepancy <2 cm NCI Mild length discrepancy <2 cm CTCAE_v5 Grade 1 Unequal Limb Length, CTCAE PT NCI Grade 1 Unequal limb length PT CTCAE_v5 ctcae5:C144449 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Upper Gastrointestinal Hemorrhage, CTCAE Grade 1 Upper gastrointestinal hemorrhage 10055356 C144449 Grade 1 Upper gastrointestinal hemorrhage Grade 1 Upper gastrointestinal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 1 Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C144450 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Ureteric Anastomotic Leak, CTCAE Grade 1 Ureteric anastomotic leak 10065814 C144450 Grade 1 Ureteric anastomotic leak Grade 1 Ureteric anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Ureteric Anastomotic Leak, CTCAE PT NCI Grade 1 Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C144451 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Urethral Anastomotic Leak, CTCAE Grade 1 Urethral anastomotic leak 10065815 C144451 Grade 1 Urethral anastomotic leak Grade 1 Urethral anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Urethral Anastomotic Leak, CTCAE PT NCI Grade 1 Urethral anastomotic leak PT CTCAE_v5 ctcae5:C144452 Present Present Grade 1 Urinary Frequency, CTCAE Grade 1 Urinary frequency 10046539 C144452 Grade 1 Urinary frequency Grade 1 Urinary frequency Present NCI Present CTCAE_v5 Grade 1 Urinary Frequency, CTCAE PT NCI Grade 1 Urinary frequency PT CTCAE_v5 ctcae5:C144453 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Urinary Tract Obstruction, CTCAE Grade 1 Urinary tract obstruction 10061574 C144453 Grade 1 Urinary tract obstruction Grade 1 Urinary tract obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Urinary Tract Obstruction, CTCAE PT NCI Grade 1 Urinary tract obstruction PT CTCAE_v5 ctcae5:C144454 Mild pain Mild pain Grade 1 Urinary Tract Pain, CTCAE Grade 1 Urinary tract pain 10062225 C144454 Grade 1 Urinary tract pain Grade 1 Urinary tract pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Urinary Tract Pain, CTCAE PT NCI Grade 1 Urinary tract pain PT CTCAE_v5 ctcae5:C144455 Present Present Grade 1 Urinary Urgency, CTCAE Grade 1 Urinary urgency 10046593 C144455 Grade 1 Urinary urgency Grade 1 Urinary urgency Present NCI Present CTCAE_v5 Grade 1 Urinary Urgency, CTCAE PT NCI Grade 1 Urinary urgency PT CTCAE_v5 ctcae5:C144456 Present Present Grade 1 Urine Discoloration, CTCAE Grade 1 Urine discoloration 10046628 C144456 Grade 1 Urine discoloration Grade 1 Urine discoloration Present NCI Present CTCAE_v5 Grade 1 Urine Discoloration, CTCAE PT NCI Grade 1 Urine discoloration PT CTCAE_v5 ctcae5:C144457 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Urostomy Leak, CTCAE Grade 1 Urostomy leak 10065882 C144457 Grade 1 Urostomy leak Grade 1 Urostomy leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Urostomy Leak, CTCAE PT NCI Grade 1 Urostomy leak PT CTCAE_v5 ctcae5:C144458 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Urostomy Obstruction, CTCAE Grade 1 Urostomy obstruction 10065883 C144458 Grade 1 Urostomy obstruction Grade 1 Urostomy obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Urostomy Obstruction, CTCAE PT NCI Grade 1 Urostomy obstruction PT CTCAE_v5 ctcae5:C144459 Minimal bleeding identified on clinical exam; intervention not indicated Minimal bleeding identified on clinical exam; intervention not indicated Grade 1 Urostomy Site Bleeding, CTCAE Grade 1 Urostomy site bleeding 10065748 C144459 Grade 1 Urostomy site bleeding Grade 1 Urostomy site bleeding Minimal bleeding identified on clinical exam; intervention not indicated NCI Minimal bleeding identified on clinical exam; intervention not indicated CTCAE_v5 Grade 1 Urostomy Site Bleeding, CTCAE PT NCI Grade 1 Urostomy site bleeding PT CTCAE_v5 ctcae5:C144460 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Uterine Anastomotic Leak, CTCAE Grade 1 Uterine anastomotic leak 10065886 C144460 Grade 1 Uterine anastomotic leak Grade 1 Uterine anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Uterine Anastomotic Leak, CTCAE PT NCI Grade 1 Uterine anastomotic leak PT CTCAE_v5 ctcae5:C144461 Asymptomatic Asymptomatic Grade 1 Uterine Fistula, CTCAE Grade 1 Uterine fistula 10065811 C144461 Grade 1 Uterine fistula Grade 1 Uterine fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Uterine Fistula, CTCAE PT NCI Grade 1 Uterine fistula PT CTCAE_v5 ctcae5:C144463 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Uterine Obstruction, CTCAE Grade 1 Uterine obstruction 10065928 C144463 Grade 1 Uterine obstruction Grade 1 Uterine obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Uterine Obstruction, CTCAE PT NCI Grade 1 Uterine obstruction PT CTCAE_v5 ctcae5:C144464 Mild pain Mild pain Grade 1 Uterine Pain, CTCAE Grade 1 Uterine pain 10046809 C144464 Grade 1 Uterine pain Grade 1 Uterine pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Uterine Pain, CTCAE PT NCI Grade 1 Uterine pain PT CTCAE_v5 ctcae5:C144465 Mild pain; erythema 2.5-5cm; induration/swelling 2.5-5cm; does not interfere with activity Mild pain; erythema 2.5-5cm; induration/swelling 2.5-5cm; does not interfere with activity Grade 1 Vaccination Complication, CTCAE Grade 1 Vaccination complication 10046861 C144465 Grade 1 Vaccination complication Grade 1 Vaccination complication Mild pain; erythema 2.5-5cm; induration/swelling 2.5-5cm; does not interfere with activity NCI Mild pain; erythema 2.5-5cm; induration/swelling 2.5-5cm; does not interfere with activity CTCAE_v5 Grade 1 Vaccination Complication, CTCAE PT NCI Grade 1 Vaccination complication PT CTCAE_v5 ctcae5:C144466 Local lymph node enlargement Local lymph node enlargement Grade 1 Vaccination Site Lymphadenopathy, CTCAE Grade 1 Vaccination site lymphadenopathy 10069480 C144466 Grade 1 Vaccination site lymphadenopathy Grade 1 Vaccination site lymphadenopathy Local lymph node enlargement NCI Local lymph node enlargement CTCAE_v5 Grade 1 Vaccination Site Lymphadenopathy, CTCAE PT NCI Grade 1 Vaccination site lymphadenopathy PT CTCAE_v5 ctcae5:C144467 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Vaginal Anastomotic Leak, CTCAE Grade 1 Vaginal anastomotic leak 10065887 C144467 Grade 1 Vaginal anastomotic leak Grade 1 Vaginal anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Vaginal Anastomotic Leak, CTCAE PT NCI Grade 1 Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C144468 Mild vaginal discharge (greater than baseline for patient) Mild vaginal discharge (greater than baseline for patient) Grade 1 Vaginal Discharge, CTCAE Grade 1 Vaginal discharge 10046901 C144468 Grade 1 Vaginal discharge Grade 1 Vaginal discharge Mild vaginal discharge (greater than baseline for patient) NCI Mild vaginal discharge (greater than baseline for patient) CTCAE_v5 Grade 1 Vaginal Discharge, CTCAE PT NCI Grade 1 Vaginal discharge PT CTCAE_v5 ctcae5:C144471 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Vaginal Infection, CTCAE Grade 1 Vaginal infection 10046914 C144471 Grade 1 Vaginal infection Grade 1 Vaginal infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Vaginal Infection, CTCAE PT NCI Grade 1 Vaginal infection PT CTCAE_v5 ctcae5:C144472 Mild discomfort or pain, edema, or redness Mild discomfort or pain, edema, or redness Grade 1 Vaginal Inflammation, CTCAE Grade 1 Vaginal inflammation 10046916 C144472 Grade 1 Vaginal inflammation Grade 1 Vaginal inflammation Mild discomfort or pain, edema, or redness NCI Mild discomfort or pain, edema, or redness CTCAE_v5 Grade 1 Vaginal Inflammation, CTCAE PT NCI Grade 1 Vaginal inflammation PT CTCAE_v5 ctcae5:C144473 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Vaginal Obstruction, CTCAE Grade 1 Vaginal obstruction 10065817 C144473 Grade 1 Vaginal obstruction Grade 1 Vaginal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Vaginal Obstruction, CTCAE PT NCI Grade 1 Vaginal obstruction PT CTCAE_v5 ctcae5:C144474 Mild pain Mild pain Grade 1 Vaginal Pain, CTCAE Grade 1 Vaginal pain 10046937 C144474 Grade 1 Vaginal pain Grade 1 Vaginal pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Vaginal Pain, CTCAE PT NCI Grade 1 Vaginal pain PT CTCAE_v5 ctcae5:C144475 Asymptomatic; mild vaginal shortening or narrowing Asymptomatic; mild vaginal shortening or narrowing Grade 1 Vaginal Stricture, CTCAE Grade 1 Vaginal stricture 10053496 C144475 Grade 1 Vaginal stricture Grade 1 Vaginal stricture Asymptomatic; mild vaginal shortening or narrowing NCI Asymptomatic; mild vaginal shortening or narrowing CTCAE_v5 Grade 1 Vaginal Stricture, CTCAE PT NCI Grade 1 Vaginal stricture PT CTCAE_v5 ctcae5:C144476 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Vagus Nerve Disorder, CTCAE Grade 1 Vagus nerve disorder 10061403 C144476 Grade 1 Vagus nerve disorder Grade 1 Vagus nerve disorder Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Vagus Nerve Disorder, CTCAE PT NCI Grade 1 Vagus nerve disorder PT CTCAE_v5 ctcae5:C144477 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Vas Deferens Anastomotic Leak, CTCAE Grade 1 Vas deferens anastomotic leak 10065888 C144477 Grade 1 Vas deferens anastomotic leak Grade 1 Vas deferens anastomotic leak Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Vas Deferens Anastomotic Leak, CTCAE PT NCI Grade 1 Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C144478 TPA administration into line with no intent for systemic therapy indicated TPA administration into line with no intent for systemic therapy indicated Grade 1 Vascular Access Complication, CTCAE Grade 1 Vascular access complication 10062169 C144478 Grade 1 Vascular access complication Grade 1 Vascular access complication TPA administration into line with no intent for systemic therapy indicated NCI TPA administration into line with no intent for systemic therapy indicated CTCAE_v5 Grade 1 Vascular Access Complication, CTCAE PT NCI Grade 1 Vascular access complication PT CTCAE_v5 ctcae5:C144479 Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Grade 1 Vascular Disorders - Other, Specify, CTCAE Grade 1 Vascular disorders - Other, specify 10047065 C144479 Grade 1 Vascular disorders - Other, specify Grade 1 Vascular disorders - Other, specify Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Vascular Disorders - Other, Specify, CTCAE PT NCI Grade 1 Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C144480 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Venous Injury, CTCAE Grade 1 Venous injury 10047228 C144480 Grade 1 Venous injury Grade 1 Venous injury Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Venous Injury, CTCAE PT NCI Grade 1 Venous injury PT CTCAE_v5 ctcae5:C144481 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Ventricular Arrhythmia, CTCAE Grade 1 Ventricular arrhythmia 10047281 C144481 Grade 1 Ventricular arrhythmia Grade 1 Ventricular arrhythmia Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Ventricular Arrhythmia, CTCAE PT NCI Grade 1 Ventricular arrhythmia PT CTCAE_v5 ctcae5:C144482 Mild symptoms Mild symptoms Grade 1 Vertigo Grade 1 Vertigo, CTCAE 10047340 C144482 Grade 1 Vertigo Grade 1 Vertigo Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Vertigo PT CTCAE_v5 Grade 1 Vertigo, CTCAE PT NCI ctcae5:C144483 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Virilization Grade 1 Virilization, CTCAE 10047488 C144483 Grade 1 Virilization Grade 1 Virilization Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Virilization PT CTCAE_v5 Grade 1 Virilization, CTCAE PT NCI ctcae5:C144484 90-75% of predicted value 90-75% of predicted value Grade 1 Vital Capacity Abnormal, CTCAE Grade 1 Vital capacity abnormal 10047580 C144484 Grade 1 Vital capacity abnormal Grade 1 Vital capacity abnormal 90-75% of predicted value NCI 90-75% of predicted value CTCAE_v5 Grade 1 Vital Capacity Abnormal, CTCAE PT NCI Grade 1 Vital capacity abnormal PT CTCAE_v5 ctcae5:C144485 Mild or intermittent change from normal voice Mild or intermittent change from normal voice Grade 1 Voice Alteration, CTCAE Grade 1 Voice alteration 10047681 C144485 Grade 1 Voice alteration Grade 1 Voice alteration Mild or intermittent change from normal voice NCI Mild or intermittent change from normal voice CTCAE_v5 Grade 1 Voice Alteration, CTCAE PT NCI Grade 1 Voice alteration PT CTCAE_v5 ctcae5:C144486 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Vulval Infection, CTCAE Grade 1 Vulval infection 10065772 C144486 Grade 1 Vulval infection Grade 1 Vulval infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Vulval Infection, CTCAE PT NCI Grade 1 Vulval infection PT CTCAE_v5 ctcae5:C144487 Intervention not indicated Intervention not indicated Grade 1 Watering Eyes, CTCAE Grade 1 Watering eyes 10047848 C144487 Grade 1 Watering eyes Grade 1 Watering eyes Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 1 Watering Eyes, CTCAE PT NCI Grade 1 Watering eyes PT CTCAE_v5 ctcae5:C144488 Detectable airway noise with minimal symptoms Detectable airway noise with minimal symptoms Grade 1 Wheezing Grade 1 Wheezing, CTCAE 10047924 C144488 Grade 1 Wheezing Grade 1 Wheezing Detectable airway noise with minimal symptoms NCI Detectable airway noise with minimal symptoms CTCAE_v5 Grade 1 Wheezing PT CTCAE_v5 Grade 1 Wheezing, CTCAE PT NCI ctcae5:C144489 <LLN-3000/mm3; <LLN-3.0 x 10e9/L <LLN-3000/mm3; <LLN-3.0 x 10e9/L Grade 1 White Blood Cell Decreased, CTCAE Grade 1 White blood cell decreased 10049182 C144489 Grade 1 White blood cell decreased Grade 1 White blood cell decreased <LLN-3000/mm3; <LLN-3.0 x 10e9/L NCI <LLN-3000/mm3; <LLN-3.0 x 10e9/L CTCAE_v5 Grade 1 White Blood Cell Decreased, CTCAE PT NCI Grade 1 White blood cell decreased PT CTCAE_v5 ctcae5:C144490 Observation only; topical intervention indicated Observation only; topical intervention indicated Grade 1 Wound Complication, CTCAE Grade 1 Wound complication 10053692 C144490 Grade 1 Wound complication Grade 1 Wound complication Observation only; topical intervention indicated NCI Observation only; topical intervention indicated CTCAE_v5 Grade 1 Wound Complication, CTCAE PT NCI Grade 1 Wound complication PT CTCAE_v5 ctcae5:C144491 Incisional separation, intervention not indicated Incisional separation, intervention not indicated Grade 1 Wound Dehiscence, CTCAE Grade 1 Wound dehiscence 10048031 C144491 Grade 1 Wound dehiscence Grade 1 Wound dehiscence Incisional separation, intervention not indicated NCI Incisional separation, intervention not indicated CTCAE_v5 Grade 1 Wound Dehiscence, CTCAE PT NCI Grade 1 Wound dehiscence PT CTCAE_v5 ctcae5:C144492 Localized, local intervention indicated Localized, local intervention indicated Grade 1 Wound Infection, CTCAE Grade 1 Wound infection 10048038 C144492 Grade 1 Wound infection Grade 1 Wound infection Localized, local intervention indicated NCI Localized, local intervention indicated CTCAE_v5 Grade 1 Wound Infection, CTCAE PT NCI Grade 1 Wound infection PT CTCAE_v5 ctcae5:C144493 Mild; non-operative intervention indicated Mild; non-operative intervention indicated Grade 1 Wrist Fracture, CTCAE Grade 1 Wrist fracture 10048049 C144493 Grade 1 Wrist fracture Grade 1 Wrist fracture Mild; non-operative intervention indicated NCI Mild; non-operative intervention indicated CTCAE_v5 Grade 1 Wrist Fracture, CTCAE PT NCI Grade 1 Wrist fracture PT CTCAE_v5 ctcae5:C144494 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Abdominal Distension, CTCAE Grade 2 Abdominal distension 10000060 C144494 Grade 2 Abdominal distension Grade 2 Abdominal distension Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Abdominal Distension, CTCAE PT NCI Grade 2 Abdominal distension PT CTCAE_v5 ctcae5:C144495 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Abdominal Infection, CTCAE Grade 2 Abdominal infection 10056519 C144495 Grade 2 Abdominal infection Grade 2 Abdominal infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Abdominal Infection, CTCAE PT NCI Grade 2 Abdominal infection PT CTCAE_v5 ctcae5:C144496 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Abdominal Pain, CTCAE Grade 2 Abdominal pain 10000081 C144496 Grade 2 Abdominal pain Grade 2 Abdominal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Abdominal Pain, CTCAE PT NCI Grade 2 Abdominal pain PT CTCAE_v5 ctcae5:C144497 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Abdominal Soft Tissue Necrosis, CTCAE Grade 2 Abdominal soft tissue necrosis 10065775 C144497 Grade 2 Abdominal soft tissue necrosis Grade 2 Abdominal soft tissue necrosis Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Abdominal Soft Tissue Necrosis, CTCAE PT NCI Grade 2 Abdominal soft tissue necrosis PT CTCAE_v5 ctcae5:C144498 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Abducens Nerve Disorder, CTCAE Grade 2 Abducens nerve disorder 10053662 C144498 Grade 2 Abducens nerve disorder Grade 2 Abducens nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Abducens Nerve Disorder, CTCAE PT NCI Grade 2 Abducens nerve disorder PT CTCAE_v5 ctcae5:C144499 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Accessory Nerve Disorder, CTCAE Grade 2 Accessory nerve disorder 10060929 C144499 Grade 2 Accessory nerve disorder Grade 2 Accessory nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Accessory Nerve Disorder, CTCAE PT NCI Grade 2 Accessory nerve disorder PT CTCAE_v5 ctcae5:C144500 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Acoustic Nerve Disorder NOS, CTCAE Grade 2 Acoustic nerve disorder NOS 10000521 C144500 Grade 2 Acoustic nerve disorder NOS Grade 2 Acoustic nerve disorder NOS Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Acoustic Nerve Disorder NOS, CTCAE PT NCI Grade 2 Acoustic nerve disorder NOS PT CTCAE_v5 ctcae5:C144501 >1.5-2.5 x ULN >1.5-2.5 x ULN Grade 2 Activated Partial Thromboplastin Time Prolonged, CTCAE Grade 2 Activated partial thromboplastin time prolonged 10000636 C144501 Grade 2 Activated partial thromboplastin time prolonged Grade 2 Activated partial thromboplastin time prolonged >1.5-2.5 x ULN NCI >1.5-2.5 x ULN CTCAE_v5 Grade 2 Activated Partial Thromboplastin Time Prolonged, CTCAE PT NCI Grade 2 Activated partial thromboplastin time prolonged PT CTCAE_v5 ctcae5:C144502 Moderate restlessness or increased motor activity; limiting instrumental ADL Moderate restlessness or increased motor activity; limiting instrumental ADL Grade 2 Akathisia Grade 2 Akathisia, CTCAE 10001540 C144502 Grade 2 Akathisia Grade 2 Akathisia Moderate restlessness or increased motor activity; limiting instrumental ADL NCI Moderate restlessness or increased motor activity; limiting instrumental ADL CTCAE_v5 Grade 2 Akathisia PT CTCAE_v5 Grade 2 Akathisia, CTCAE PT NCI ctcae5:C144503 >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal Grade 2 Alanine Aminotransferase Increased, CTCAE Grade 2 Alanine aminotransferase increased 10001551 C144503 Grade 2 Alanine aminotransferase increased Grade 2 Alanine aminotransferase increased >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal NCI >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal CTCAE_v5 Grade 2 Alanine Aminotransferase Increased, CTCAE PT NCI Grade 2 Alanine aminotransferase increased PT CTCAE_v5 ctcae5:C144504 Present Present Grade 2 Alcohol Intolerance, CTCAE Grade 2 Alcohol intolerance 10001598 C144504 Grade 2 Alcohol intolerance Grade 2 Alcohol intolerance Present NCI Present CTCAE_v5 Grade 2 Alcohol Intolerance, CTCAE PT NCI Grade 2 Alcohol intolerance PT CTCAE_v5 ctcae5:C144505 >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal Grade 2 Alkaline Phosphatase Increased, CTCAE Grade 2 Alkaline phosphatase increased 10001675 C144505 Grade 2 Alkaline phosphatase increased Grade 2 Alkaline phosphatase increased >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal NCI >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal CTCAE_v5 Grade 2 Alkaline Phosphatase Increased, CTCAE PT NCI Grade 2 Alkaline phosphatase increased PT CTCAE_v5 ctcae5:C144506 Oral intervention indicated Oral intervention indicated Grade 2 Allergic Reaction, CTCAE Grade 2 Allergic reaction 10001718 C144506 Grade 2 Allergic reaction Grade 2 Allergic reaction Oral intervention indicated NCI Oral intervention indicated CTCAE_v5 Grade 2 Allergic Reaction, CTCAE PT NCI Grade 2 Allergic reaction PT CTCAE_v5 ctcae5:C144507 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Allergic Rhinitis, CTCAE Grade 2 Allergic rhinitis 10001723 C144507 Grade 2 Allergic rhinitis Grade 2 Allergic rhinitis Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Allergic Rhinitis, CTCAE PT NCI Grade 2 Allergic rhinitis PT CTCAE_v5 ctcae5:C144508 Present Present Grade 2 Amenorrhea Grade 2 Amenorrhea, CTCAE 10001927 C144508 Grade 2 Amenorrhea Grade 2 Amenorrhea Present NCI Present CTCAE_v5 Grade 2 Amenorrhea PT CTCAE_v5 Grade 2 Amenorrhea, CTCAE PT NCI ctcae5:C144509 Moderate; short term memory loss; limiting instrumental ADL Moderate; short term memory loss; limiting instrumental ADL Grade 2 Amnesia Grade 2 Amnesia, CTCAE 10001949 C144509 Grade 2 Amnesia Grade 2 Amnesia Moderate; short term memory loss; limiting instrumental ADL NCI Moderate; short term memory loss; limiting instrumental ADL CTCAE_v5 Grade 2 Amnesia PT CTCAE_v5 Grade 2 Amnesia, CTCAE PT NCI ctcae5:C144510 Symptomatic Symptomatic Grade 2 Anal Fissure, CTCAE Grade 2 Anal fissure 10002153 C144510 Grade 2 Anal fissure Grade 2 Anal fissure Symptomatic NCI Symptomatic CTCAE_v5 Grade 2 Anal Fissure, CTCAE PT NCI Grade 2 Anal fissure PT CTCAE_v5 ctcae5:C144511 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Anal Fistula, CTCAE Grade 2 Anal fistula 10002156 C144511 Grade 2 Anal fistula Grade 2 Anal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Anal Fistula, CTCAE PT NCI Grade 2 Anal fistula PT CTCAE_v5 ctcae5:C144512 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Anal Hemorrhage, CTCAE Grade 2 Anal hemorrhage 10055226 C144512 Grade 2 Anal hemorrhage Grade 2 Anal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Anal Hemorrhage, CTCAE PT NCI Grade 2 Anal hemorrhage PT CTCAE_v5 ctcae5:C144513 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Anal Mucositis, CTCAE Grade 2 Anal mucositis 10065721 C144513 Grade 2 Anal mucositis Grade 2 Anal mucositis Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Anal Mucositis, CTCAE PT NCI Grade 2 Anal mucositis PT CTCAE_v5 ctcae5:C144514 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Anal Pain, CTCAE Grade 2 Anal pain 10002167 C144514 Grade 2 Anal pain Grade 2 Anal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Anal Pain, CTCAE PT NCI Grade 2 Anal pain PT CTCAE_v5 ctcae5:C144515 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Anal Stenosis, CTCAE Grade 2 Anal stenosis 10002176 C144515 Grade 2 Anal stenosis Grade 2 Anal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Anal Stenosis, CTCAE PT NCI Grade 2 Anal stenosis PT CTCAE_v5 ctcae5:C144516 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Anal Ulcer, CTCAE Grade 2 Anal ulcer 10002180 C144516 Grade 2 Anal ulcer Grade 2 Anal ulcer Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Anal Ulcer, CTCAE PT NCI Grade 2 Anal ulcer PT CTCAE_v5 ctcae5:C144517 Hgb <10.0-8.0 g/dL; <6.2-4.9 mmol/L; <100-80g/L Hgb <10.0-8.0 g/dL; <6.2-4.9 mmol/L; <100-80g/L Grade 2 Anemia Grade 2 Anemia, CTCAE 10002272 C144517 Grade 2 Anemia Grade 2 Anemia Hgb <10.0-8.0 g/dL; <6.2-4.9 mmol/L; <100-80g/L NCI Hgb <10.0-8.0 g/dL; <6.2-4.9 mmol/L; <100-80g/L CTCAE_v5 Grade 2 Anemia PT CTCAE_v5 Grade 2 Anemia, CTCAE PT NCI ctcae5:C144518 Limiting instrumental ADL; outpatient operative intervention indicated Limiting instrumental ADL; outpatient operative intervention indicated Grade 2 Ankle Fracture, CTCAE Grade 2 Ankle fracture 10002544 C144518 Grade 2 Ankle fracture Grade 2 Ankle fracture Limiting instrumental ADL; outpatient operative intervention indicated NCI Limiting instrumental ADL; outpatient operative intervention indicated CTCAE_v5 Grade 2 Ankle Fracture, CTCAE PT NCI Grade 2 Ankle fracture PT CTCAE_v5 ctcae5:C144519 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Anorectal Infection, CTCAE Grade 2 Anorectal infection 10061640 C144519 Grade 2 Anorectal infection Grade 2 Anorectal infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Anorectal Infection, CTCAE PT NCI Grade 2 Anorectal infection PT CTCAE_v5 ctcae5:C144520 Inability to achieve orgasm adversely affecting relationship Inability to achieve orgasm adversely affecting relationship Grade 2 Anorgasmia Grade 2 Anorgasmia, CTCAE 10002652 C144520 Grade 2 Anorgasmia Grade 2 Anorgasmia Inability to achieve orgasm adversely affecting relationship NCI Inability to achieve orgasm adversely affecting relationship CTCAE_v5 Grade 2 Anorgasmia PT CTCAE_v5 Grade 2 Anorgasmia, CTCAE PT NCI ctcae5:C144521 Operative intervention not indicated Operative intervention not indicated Grade 2 Aortic Injury, CTCAE Grade 2 Aortic injury 10002899 C144521 Grade 2 Aortic injury Grade 2 Aortic injury Operative intervention not indicated NCI Operative intervention not indicated CTCAE_v5 Grade 2 Aortic Injury, CTCAE PT NCI Grade 2 Aortic injury PT CTCAE_v5 ctcae5:C144522 Asymptomatic; moderate regurgitation or stenosis by imaging Asymptomatic; moderate regurgitation or stenosis by imaging Grade 2 Aortic Valve Disease, CTCAE Grade 2 Aortic valve disease 10061589 C144522 Grade 2 Aortic valve disease Grade 2 Aortic valve disease Asymptomatic; moderate regurgitation or stenosis by imaging NCI Asymptomatic; moderate regurgitation or stenosis by imaging CTCAE_v5 Grade 2 Aortic Valve Disease, CTCAE PT NCI Grade 2 Aortic valve disease PT CTCAE_v5 ctcae5:C144523 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Arachnoiditis Grade 2 Arachnoiditis, CTCAE 10003074 C144523 Grade 2 Arachnoiditis Grade 2 Arachnoiditis Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Arachnoiditis PT CTCAE_v5 Grade 2 Arachnoiditis, CTCAE PT NCI ctcae5:C144524 Symptomatic; repair or revision not indicated Symptomatic; repair or revision not indicated Grade 2 Arterial Injury, CTCAE Grade 2 Arterial injury 10003162 C144524 Grade 2 Arterial injury Grade 2 Arterial injury Symptomatic; repair or revision not indicated NCI Symptomatic; repair or revision not indicated CTCAE_v5 Grade 2 Arterial Injury, CTCAE PT NCI Grade 2 Arterial injury PT CTCAE_v5 ctcae5:C144525 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Arthralgia Grade 2 Arthralgia, CTCAE 10003239 C144525 Grade 2 Arthralgia Grade 2 Arthralgia Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Arthralgia PT CTCAE_v5 Grade 2 Arthralgia, CTCAE PT NCI ctcae5:C144526 Moderate pain associated with signs of inflammation, erythema, or joint swelling; limiting instrumental ADL Moderate pain associated with signs of inflammation, erythema, or joint swelling; limiting instrumental ADL Grade 2 Arthritis Grade 2 Arthritis, CTCAE 10003246 C144526 Grade 2 Arthritis Grade 2 Arthritis Moderate pain associated with signs of inflammation, erythema, or joint swelling; limiting instrumental ADL NCI Moderate pain associated with signs of inflammation, erythema, or joint swelling; limiting instrumental ADL CTCAE_v5 Grade 2 Arthritis PT CTCAE_v5 Grade 2 Arthritis, CTCAE PT NCI ctcae5:C144527 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Ascites Grade 2 Ascites, CTCAE 10003445 C144527 Grade 2 Ascites Grade 2 Ascites Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Ascites PT CTCAE_v5 Grade 2 Ascites, CTCAE PT NCI ctcae5:C144528 >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal Grade 2 Aspartate Aminotransferase Increased, CTCAE Grade 2 Aspartate aminotransferase increased 10003481 C144528 Grade 2 Aspartate aminotransferase increased Grade 2 Aspartate aminotransferase increased >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal NCI >3.0-5.0 x ULN if baseline was normal; >3.0-5.0 x baseline if baseline was abnormal CTCAE_v5 Grade 2 Aspartate Aminotransferase Increased, CTCAE PT NCI Grade 2 Aspartate aminotransferase increased PT CTCAE_v5 ctcae5:C144529 Non-urgent intervention indicated Non-urgent intervention indicated Grade 2 Atrioventricular Block Complete, CTCAE Grade 2 Atrioventricular block complete 10003673 C144529 Grade 2 Atrioventricular block complete Grade 2 Atrioventricular block complete Non-urgent intervention indicated NCI Non-urgent intervention indicated CTCAE_v5 Grade 2 Atrioventricular Block Complete, CTCAE PT NCI Grade 2 Atrioventricular block complete PT CTCAE_v5 ctcae5:C144530 Non-urgent intervention indicated Non-urgent intervention indicated Grade 2 Atrioventricular Block First Degree, CTCAE Grade 2 Atrioventricular block first degree 10003674 C144530 Grade 2 Atrioventricular block first degree Grade 2 Atrioventricular block first degree Non-urgent intervention indicated NCI Non-urgent intervention indicated CTCAE_v5 Grade 2 Atrioventricular Block First Degree, CTCAE PT NCI Grade 2 Atrioventricular block first degree PT CTCAE_v5 ctcae5:C144531 Evidence of autoimmune reaction involving a non-essential organ or function (e.g., hypothyroidism) Evidence of autoimmune reaction involving a non-essential organ or function (e.g., hypothyroidism) Grade 2 Autoimmune Disorder, CTCAE Grade 2 Autoimmune disorder 10061664 C144531 Grade 2 Autoimmune disorder Grade 2 Autoimmune disorder Evidence of autoimmune reaction involving a non-essential organ or function (e.g., hypothyroidism) NCI Evidence of autoimmune reaction involving a non-essential organ or function (e.g., hypothyroidism) CTCAE_v5 Grade 2 Autoimmune Disorder, CTCAE PT NCI Grade 2 Autoimmune disorder PT CTCAE_v5 ctcae5:C144532 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Avascular Necrosis, CTCAE Grade 2 Avascular necrosis 10066480 C144532 Grade 2 Avascular necrosis Grade 2 Avascular necrosis Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Avascular Necrosis, CTCAE PT NCI Grade 2 Avascular necrosis PT CTCAE_v5 ctcae5:C144533 Absence of sperm in ejaculate Absence of sperm in ejaculate Grade 2 Azoospermia Grade 2 Azoospermia, CTCAE 10003883 C144533 Grade 2 Azoospermia Grade 2 Azoospermia Absence of sperm in ejaculate NCI Absence of sperm in ejaculate CTCAE_v5 Grade 2 Azoospermia PT CTCAE_v5 Grade 2 Azoospermia, CTCAE PT NCI ctcae5:C144534 Blood culture positive with no signs or symptoms Blood culture positive with no signs or symptoms Grade 2 Bacteremia Grade 2 Bacteremia, CTCAE 10003999 C144534 Grade 2 Bacteremia Grade 2 Bacteremia Blood culture positive with no signs or symptoms NCI Blood culture positive with no signs or symptoms CTCAE_v5 Grade 2 Bacteremia PT CTCAE_v5 Grade 2 Bacteremia, CTCAE PT NCI ctcae5:C144535 Intervention initiated (including over the counter medications) Intervention initiated (including over the counter medications) Grade 2 Belching Grade 2 Belching, CTCAE 10004222 C144535 Grade 2 Belching Grade 2 Belching Intervention initiated (including over the counter medications) NCI Intervention initiated (including over the counter medications) CTCAE_v5 Grade 2 Belching PT CTCAE_v5 Grade 2 Belching, CTCAE PT NCI ctcae5:C144536 Symptomatic; altered GI function; IV fluids indicated <24 hrs Symptomatic; altered GI function; IV fluids indicated <24 hrs Grade 2 Bile Duct Stenosis, CTCAE Grade 2 Bile duct stenosis 10051341 C144536 Grade 2 Bile duct stenosis Grade 2 Bile duct stenosis Symptomatic; altered GI function; IV fluids indicated <24 hrs NCI Symptomatic; altered GI function; IV fluids indicated <24 hrs CTCAE_v5 Grade 2 Bile Duct Stenosis, CTCAE PT NCI Grade 2 Bile duct stenosis PT CTCAE_v5 ctcae5:C144537 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Biliary Anastomotic Leak, CTCAE Grade 2 Biliary anastomotic leak 10050458 C144537 Grade 2 Biliary anastomotic leak Grade 2 Biliary anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Biliary Anastomotic Leak, CTCAE PT NCI Grade 2 Biliary anastomotic leak PT CTCAE_v5 ctcae5:C144538 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Biliary Fistula, CTCAE Grade 2 Biliary fistula 10004665 C144538 Grade 2 Biliary fistula Grade 2 Biliary fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Biliary Fistula, CTCAE PT NCI Grade 2 Biliary fistula PT CTCAE_v5 ctcae5:C144539 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Biliary Tract Infection, CTCAE Grade 2 Biliary tract infection 10061695 C144539 Grade 2 Biliary tract infection Grade 2 Biliary tract infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Biliary Tract Infection, CTCAE PT NCI Grade 2 Biliary tract infection PT CTCAE_v5 ctcae5:C144540 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Bladder Anastomotic Leak, CTCAE Grade 2 Bladder anastomotic leak 10065802 C144540 Grade 2 Bladder anastomotic leak Grade 2 Bladder anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Bladder Anastomotic Leak, CTCAE PT NCI Grade 2 Bladder anastomotic leak PT CTCAE_v5 ctcae5:C144541 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Bladder Infection, CTCAE Grade 2 Bladder infection 10005047 C144541 Grade 2 Bladder infection Grade 2 Bladder infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Bladder Infection, CTCAE PT NCI Grade 2 Bladder infection PT CTCAE_v5 ctcae5:C144543 Symptomatic, decreased oral intake; change in bowel function Symptomatic, decreased oral intake; change in bowel function Grade 2 Bloating Grade 2 Bloating, CTCAE 10005265 C144543 Grade 2 Bloating Grade 2 Bloating Symptomatic, decreased oral intake; change in bowel function NCI Symptomatic, decreased oral intake; change in bowel function CTCAE_v5 Grade 2 Bloating PT CTCAE_v5 Grade 2 Bloating, CTCAE PT NCI ctcae5:C144544 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Grade 2 Blood and lymphatic system disorders - Other, specify 10005329 C144544 Grade 2 Blood and lymphatic system disorders - Other, specify Grade 2 Blood and lymphatic system disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Grade 2 Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C144545 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Blood Antidiuretic Hormone Abnormal, CTCAE Grade 2 Blood antidiuretic hormone abnormal 10005332 C144545 Grade 2 Blood antidiuretic hormone abnormal Grade 2 Blood antidiuretic hormone abnormal Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Blood Antidiuretic Hormone Abnormal, CTCAE PT NCI Grade 2 Blood antidiuretic hormone abnormal PT CTCAE_v5 ctcae5:C144546 >1.5-3.0 x ULN if baseline was normal; >1.5-3.0 x baseline if baseline was abnormal >1.5-3.0 x ULN if baseline was normal; >1.5-3.0 x baseline if baseline was abnormal Grade 2 Blood Bilirubin Increased, CTCAE Grade 2 Blood bilirubin increased 10005364 C144546 Grade 2 Blood bilirubin increased Grade 2 Blood bilirubin increased >1.5-3.0 x ULN if baseline was normal; >1.5-3.0 x baseline if baseline was abnormal NCI >1.5-3.0 x ULN if baseline was normal; >1.5-3.0 x baseline if baseline was abnormal CTCAE_v5 Grade 2 Blood Bilirubin Increased, CTCAE PT NCI Grade 2 Blood bilirubin increased PT CTCAE_v5 ctcae5:C144547 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Blood Corticotrophin Decreased, CTCAE Grade 2 Blood corticotrophin decreased 10005452 C144547 Grade 2 Blood corticotrophin decreased Grade 2 Blood corticotrophin decreased Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Blood Corticotrophin Decreased, CTCAE PT NCI Grade 2 Blood corticotrophin decreased PT CTCAE_v5 ctcae5:C144548 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Blood Gonadotrophin Abnormal, CTCAE Grade 2 Blood gonadotrophin abnormal 10005561 C144548 Grade 2 Blood gonadotrophin abnormal Grade 2 Blood gonadotrophin abnormal Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Blood Gonadotrophin Abnormal, CTCAE PT NCI Grade 2 Blood gonadotrophin abnormal PT CTCAE_v5 ctcae5:C144549 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Blood Prolactin Abnormal, CTCAE Grade 2 Blood prolactin abnormal 10005778 C144549 Grade 2 Blood prolactin abnormal Grade 2 Blood prolactin abnormal Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Blood Prolactin Abnormal, CTCAE PT NCI Grade 2 Blood prolactin abnormal PT CTCAE_v5 ctcae5:C144550 Pronounced odor; psychosocial impact; patient seeks medical intervention Pronounced odor; psychosocial impact; patient seeks medical intervention Grade 2 Body Odor, CTCAE Grade 2 Body odor 10005901 C144550 Grade 2 Body odor Grade 2 Body odor Pronounced odor; psychosocial impact; patient seeks medical intervention NCI Pronounced odor; psychosocial impact; patient seeks medical intervention CTCAE_v5 Grade 2 Body Odor, CTCAE PT NCI Grade 2 Body odor PT CTCAE_v5 ctcae5:C144551 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Bone Infection, CTCAE Grade 2 Bone infection 10061017 C144551 Grade 2 Bone infection Grade 2 Bone infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Bone Infection, CTCAE PT NCI Grade 2 Bone infection PT CTCAE_v5 ctcae5:C144552 Moderately hypocellular or >25-<50% reduction from normal cellularity for age Moderately hypocellular or >25-<50% reduction from normal cellularity for age Grade 2 Bone Marrow Hypocellular, CTCAE Grade 2 Bone marrow hypocellular 10048580 C144552 Grade 2 Bone marrow hypocellular Grade 2 Bone marrow hypocellular Moderately hypocellular or >25-<50% reduction from normal cellularity for age NCI Moderately hypocellular or >25-<50% reduction from normal cellularity for age CTCAE_v5 Grade 2 Bone Marrow Hypocellular, CTCAE PT NCI Grade 2 Bone marrow hypocellular PT CTCAE_v5 ctcae5:C144553 Moderate asymmetry; moderate atrophy Moderate asymmetry; moderate atrophy Grade 2 Breast Atrophy, CTCAE Grade 2 Breast atrophy 10006179 C144553 Grade 2 Breast atrophy Grade 2 Breast atrophy Moderate asymmetry; moderate atrophy NCI Moderate asymmetry; moderate atrophy CTCAE_v5 Grade 2 Breast Atrophy, CTCAE PT NCI Grade 2 Breast atrophy PT CTCAE_v5 ctcae5:C144554 Local infection with moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Local infection with moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Breast Infection, CTCAE Grade 2 Breast infection 10006259 C144554 Grade 2 Breast infection Grade 2 Breast infection Local infection with moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Local infection with moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Breast Infection, CTCAE PT NCI Grade 2 Breast infection PT CTCAE_v5 ctcae5:C144555 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Bronchial Fistula, CTCAE Grade 2 Bronchial fistula 10006437 C144555 Grade 2 Bronchial fistula Grade 2 Bronchial fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Bronchial Fistula, CTCAE PT NCI Grade 2 Bronchial fistula PT CTCAE_v5 ctcae5:C144556 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Bronchial Infection, CTCAE Grade 2 Bronchial infection 10055078 C144556 Grade 2 Bronchial infection Grade 2 Bronchial infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Bronchial Infection, CTCAE PT NCI Grade 2 Bronchial infection PT CTCAE_v5 ctcae5:C144557 Symptomatic (e.g., mild wheezing); endoscopic evaluation indicated; radiographic evidence of atelectasis/lobar collapse; medical management indicated (e.g., steroids, bronchodilators) Symptomatic (e.g., mild wheezing); endoscopic evaluation indicated; radiographic evidence of atelectasis/lobar collapse; medical management indicated (e.g., steroids, bronchodilators) Grade 2 Bronchial Obstruction, CTCAE Grade 2 Bronchial obstruction 10006440 C144557 Grade 2 Bronchial obstruction Grade 2 Bronchial obstruction Symptomatic (e.g., mild wheezing); endoscopic evaluation indicated; radiographic evidence of atelectasis/lobar collapse; medical management indicated (e.g., steroids, bronchodilators) NCI Symptomatic (e.g., mild wheezing); endoscopic evaluation indicated; radiographic evidence of atelectasis/lobar collapse; medical management indicated (e.g., steroids, bronchodilators) CTCAE_v5 Grade 2 Bronchial Obstruction, CTCAE PT NCI Grade 2 Bronchial obstruction PT CTCAE_v5 ctcae5:C144558 Symptomatic (e.g., rhonchi or wheezing) but without respiratory distress; medical intervention indicated (e.g., steroids, bronchodilators) Symptomatic (e.g., rhonchi or wheezing) but without respiratory distress; medical intervention indicated (e.g., steroids, bronchodilators) Grade 2 Bronchial Stricture, CTCAE Grade 2 Bronchial stricture 10063524 C144558 Grade 2 Bronchial stricture Grade 2 Bronchial stricture Symptomatic (e.g., rhonchi or wheezing) but without respiratory distress; medical intervention indicated (e.g., steroids, bronchodilators) NCI Symptomatic (e.g., rhonchi or wheezing) but without respiratory distress; medical intervention indicated (e.g., steroids, bronchodilators) CTCAE_v5 Grade 2 Bronchial Stricture, CTCAE PT NCI Grade 2 Bronchial stricture PT CTCAE_v5 ctcae5:C144559 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Bronchopleural Fistula, CTCAE Grade 2 Bronchopleural fistula 10053481 C144559 Grade 2 Bronchopleural fistula Grade 2 Bronchopleural fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Bronchopleural Fistula, CTCAE PT NCI Grade 2 Bronchopleural fistula PT CTCAE_v5 ctcae5:C144560 Moderate symptoms; invasive intervention not indicated Moderate symptoms; invasive intervention not indicated Grade 2 Bronchopulmonary Hemorrhage, CTCAE Grade 2 Bronchopulmonary hemorrhage 10065746 C144560 Grade 2 Bronchopulmonary hemorrhage Grade 2 Bronchopulmonary hemorrhage Moderate symptoms; invasive intervention not indicated NCI Moderate symptoms; invasive intervention not indicated CTCAE_v5 Grade 2 Bronchopulmonary Hemorrhage, CTCAE PT NCI Grade 2 Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C144561 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Bronchospasm Grade 2 Bronchospasm, CTCAE 10006482 C144561 Grade 2 Bronchospasm Grade 2 Bronchospasm Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Bronchospasm PT CTCAE_v5 Grade 2 Bronchospasm, CTCAE PT NCI ctcae5:C144562 Generalized Generalized Grade 2 Bruising Grade 2 Bruising, CTCAE 10006504 C144562 Grade 2 Bruising Grade 2 Bruising Generalized NCI Generalized CTCAE_v5 Grade 2 Bruising PT CTCAE_v5 Grade 2 Bruising, CTCAE PT NCI ctcae5:C144563 Medical management indicated Medical management indicated Grade 2 Budd-Chiari Syndrome, CTCAE Grade 2 Budd-Chiari syndrome 10006537 C144563 Grade 2 Budd-Chiari syndrome Grade 2 Budd-Chiari syndrome Medical management indicated NCI Medical management indicated CTCAE_v5 Grade 2 Budd-Chiari Syndrome, CTCAE PT NCI Grade 2 Budd-Chiari syndrome PT CTCAE_v5 ctcae5:C144564 Blisters covering 10-30% BSA; painful blisters; limiting instrumental ADL Blisters covering 10-30% BSA; painful blisters; limiting instrumental ADL Grade 2 Bullous Dermatitis, CTCAE Grade 2 Bullous dermatitis 10006556 C144564 Grade 2 Bullous dermatitis Grade 2 Bullous dermatitis Blisters covering 10-30% BSA; painful blisters; limiting instrumental ADL NCI Blisters covering 10-30% BSA; painful blisters; limiting instrumental ADL CTCAE_v5 Grade 2 Bullous Dermatitis, CTCAE PT NCI Grade 2 Bullous dermatitis PT CTCAE_v5 ctcae5:C144565 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Capillary Leak Syndrome, CTCAE Grade 2 Capillary leak syndrome 10007196 C144565 Grade 2 Capillary leak syndrome Grade 2 Capillary leak syndrome Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Capillary Leak Syndrome, CTCAE PT NCI Grade 2 Capillary leak syndrome PT CTCAE_v5 ctcae5:C144566 6-8 units below LLN; for follow-up, an asymptomatic decrease of >5-8 units (ml/min/mm Hg) below the baseline value; symptomatic and intervention not indicated 6-8 units below LLN; for follow-up, an asymptomatic decrease of >5-8 units (ml/min/mm Hg) below the baseline value; symptomatic and intervention not indicated Grade 2 Carbon Monoxide Diffusing Capacity Decreased, CTCAE Grade 2 Carbon monoxide diffusing capacity decreased 10065906 C144566 Grade 2 Carbon monoxide diffusing capacity decreased Grade 2 Carbon monoxide diffusing capacity decreased 6-8 units below LLN; for follow-up, an asymptomatic decrease of >5-8 units (ml/min/mm Hg) below the baseline value; symptomatic and intervention not indicated NCI 6-8 units below LLN; for follow-up, an asymptomatic decrease of >5-8 units (ml/min/mm Hg) below the baseline value; symptomatic and intervention not indicated CTCAE_v5 Grade 2 Carbon Monoxide Diffusing Capacity Decreased, CTCAE PT NCI Grade 2 Carbon monoxide diffusing capacity decreased PT CTCAE_v5 ctcae5:C144567 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Cardiac Disorders - Other, Specify, CTCAE Grade 2 Cardiac disorders - Other, specify 10007541 C144567 Grade 2 Cardiac disorders - Other, specify Grade 2 Cardiac disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Cardiac Disorders - Other, Specify, CTCAE PT NCI Grade 2 Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C144568 Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Catheter Related Infection, CTCAE Grade 2 Catheter related infection 10007810 C144568 Grade 2 Catheter related infection Grade 2 Catheter related infection Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Catheter Related Infection, CTCAE PT NCI Grade 2 Catheter related infection PT CTCAE_v5 ctcae5:C144569 <500-200/mm3; <0.5-0.2 x 10e9/L <500-200/mm3; <0.5-0.2 x 10e9/L Grade 2 CD4 Lymphocytes Decreased, CTCAE Grade 2 CD4 lymphocytes decreased 10007839 C144569 Grade 2 CD4 lymphocytes decreased Grade 2 CD4 lymphocytes decreased <500-200/mm3; <0.5-0.2 x 10e9/L NCI <500-200/mm3; <0.5-0.2 x 10e9/L CTCAE_v5 Grade 2 CD4 Lymphocytes Decreased, CTCAE PT NCI Grade 2 CD4 lymphocytes decreased PT CTCAE_v5 ctcae5:C144570 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Cecal Hemorrhage, CTCAE Grade 2 Cecal hemorrhage 10065747 C144570 Grade 2 Cecal hemorrhage Grade 2 Cecal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Cecal Hemorrhage, CTCAE PT NCI Grade 2 Cecal hemorrhage PT CTCAE_v5 ctcae5:C144571 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Cecal Infection, CTCAE Grade 2 Cecal infection 10065761 C144571 Grade 2 Cecal infection Grade 2 Cecal infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Cecal Infection, CTCAE PT NCI Grade 2 Cecal infection PT CTCAE_v5 ctcae5:C144572 Moderate symptoms; corticosteroids indicated Moderate symptoms; corticosteroids indicated Grade 2 Central Nervous System Necrosis, CTCAE Grade 2 Central nervous system necrosis 10065784 C144572 Grade 2 Central nervous system necrosis Grade 2 Central nervous system necrosis Moderate symptoms; corticosteroids indicated NCI Moderate symptoms; corticosteroids indicated CTCAE_v5 Grade 2 Central Nervous System Necrosis, CTCAE PT NCI Grade 2 Central nervous system necrosis PT CTCAE_v5 ctcae5:C144573 Post-craniotomy: moderate symptoms; medical intervention indicated; Post-lumbar puncture: persistent moderate symptoms; blood patch indicated Post-craniotomy: moderate symptoms; medical intervention indicated; Post-lumbar puncture: persistent moderate symptoms; blood patch indicated Grade 2 Cerebrospinal Fluid Leakage, CTCAE Grade 2 Cerebrospinal fluid leakage 10008164 C144573 Grade 2 Cerebrospinal fluid leakage Grade 2 Cerebrospinal fluid leakage Post-craniotomy: moderate symptoms; medical intervention indicated; Post-lumbar puncture: persistent moderate symptoms; blood patch indicated NCI Post-craniotomy: moderate symptoms; medical intervention indicated; Post-lumbar puncture: persistent moderate symptoms; blood patch indicated CTCAE_v5 Grade 2 Cerebrospinal Fluid Leakage, CTCAE PT NCI Grade 2 Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C144574 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Cervicitis Infection, CTCAE Grade 2 Cervicitis infection 10008330 C144574 Grade 2 Cervicitis infection Grade 2 Cervicitis infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Cervicitis Infection, CTCAE PT NCI Grade 2 Cervicitis infection PT CTCAE_v5 ctcae5:C144575 Moderate pain; pain on exertion; limiting instrumental ADL; hemodynamically stable Moderate pain; pain on exertion; limiting instrumental ADL; hemodynamically stable Grade 2 Chest Pain - Cardiac, CTCAE Grade 2 Chest pain - cardiac 10008481 C144575 Grade 2 Chest pain - cardiac Grade 2 Chest pain - cardiac Moderate pain; pain on exertion; limiting instrumental ADL; hemodynamically stable NCI Moderate pain; pain on exertion; limiting instrumental ADL; hemodynamically stable CTCAE_v5 Grade 2 Chest Pain - Cardiac, CTCAE PT NCI Grade 2 Chest pain - cardiac PT CTCAE_v5 ctcae5:C144576 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Chest Wall Necrosis, CTCAE Grade 2 Chest wall necrosis 10048831 C144576 Grade 2 Chest wall necrosis Grade 2 Chest wall necrosis Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Chest Wall Necrosis, CTCAE PT NCI Grade 2 Chest wall necrosis PT CTCAE_v5 ctcae5:C144577 Moderate tremor of the entire body; narcotics indicated Moderate tremor of the entire body; narcotics indicated Grade 2 Chills Grade 2 Chills, CTCAE 10008531 C144577 Grade 2 Chills Grade 2 Chills Moderate tremor of the entire body; narcotics indicated NCI Moderate tremor of the entire body; narcotics indicated CTCAE_v5 Grade 2 Chills PT CTCAE_v5 Grade 2 Chills, CTCAE PT NCI ctcae5:C144578 >300-400 mg/dL; >7.75-10.34 mmol/L >300-400 mg/dL; >7.75-10.34 mmol/L Grade 2 Cholesterol High, CTCAE Grade 2 Cholesterol high 10008661 C144578 Grade 2 Cholesterol high Grade 2 Cholesterol high >300-400 mg/dL; >7.75-10.34 mmol/L NCI >300-400 mg/dL; >7.75-10.34 mmol/L CTCAE_v5 Grade 2 Cholesterol High, CTCAE PT NCI Grade 2 Cholesterol high PT CTCAE_v5 ctcae5:C144579 eGFR or CrCl 59-30 ml/min/1.73 m2 eGFR or CrCl 59-30 ml/min/1.73 m2 Grade 2 Chronic Kidney Disease, CTCAE Grade 2 Chronic kidney disease 10064848 C144579 Grade 2 Chronic kidney disease Grade 2 Chronic kidney disease eGFR or CrCl 59-30 ml/min/1.73 m2 NCI eGFR or CrCl 59-30 ml/min/1.73 m2 CTCAE_v5 Grade 2 Chronic Kidney Disease, CTCAE PT NCI Grade 2 Chronic kidney disease PT CTCAE_v5 ctcae5:C144580 Symptomatic; medical intervention indicated (e.g., fat-restricted diet); paracentesis or tube drainage indicated Symptomatic; medical intervention indicated (e.g., fat-restricted diet); paracentesis or tube drainage indicated Grade 2 Chylous Ascites, CTCAE Grade 2 Chylous ascites 10009167 C144580 Grade 2 Chylous ascites Grade 2 Chylous ascites Symptomatic; medical intervention indicated (e.g., fat-restricted diet); paracentesis or tube drainage indicated NCI Symptomatic; medical intervention indicated (e.g., fat-restricted diet); paracentesis or tube drainage indicated CTCAE_v5 Grade 2 Chylous Ascites, CTCAE PT NCI Grade 2 Chylous ascites PT CTCAE_v5 ctcae5:C144581 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Colonic Fistula, CTCAE Grade 2 Colonic fistula 10009995 C144581 Grade 2 Colonic fistula Grade 2 Colonic fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Colonic Fistula, CTCAE PT NCI Grade 2 Colonic fistula PT CTCAE_v5 ctcae5:C144582 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Colonic Hemorrhage, CTCAE Grade 2 Colonic hemorrhage 10009998 C144582 Grade 2 Colonic hemorrhage Grade 2 Colonic hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Colonic Hemorrhage, CTCAE PT NCI Grade 2 Colonic hemorrhage PT CTCAE_v5 ctcae5:C144583 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Colonic Obstruction, CTCAE Grade 2 Colonic obstruction 10010000 C144583 Grade 2 Colonic obstruction Grade 2 Colonic obstruction Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Colonic Obstruction, CTCAE PT NCI Grade 2 Colonic obstruction PT CTCAE_v5 ctcae5:C144584 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Colonic Perforation, CTCAE Grade 2 Colonic perforation 10010001 C144584 Grade 2 Colonic perforation Grade 2 Colonic perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Colonic Perforation, CTCAE PT NCI Grade 2 Colonic perforation PT CTCAE_v5 ctcae5:C144585 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Colonic Stenosis, CTCAE Grade 2 Colonic stenosis 10010004 C144585 Grade 2 Colonic stenosis Grade 2 Colonic stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Colonic Stenosis, CTCAE PT NCI Grade 2 Colonic stenosis PT CTCAE_v5 ctcae5:C144586 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Colonic Ulcer, CTCAE Grade 2 Colonic ulcer 10010006 C144586 Grade 2 Colonic ulcer Grade 2 Colonic ulcer Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Colonic Ulcer, CTCAE PT NCI Grade 2 Colonic ulcer PT CTCAE_v5 ctcae5:C144587 Moderate impairment in attention or decreased level of concentration; limiting instrumental ADL Moderate impairment in attention or decreased level of concentration; limiting instrumental ADL Grade 2 Concentration Impairment, CTCAE Grade 2 Concentration impairment 10010250 C144587 Grade 2 Concentration impairment Grade 2 Concentration impairment Moderate impairment in attention or decreased level of concentration; limiting instrumental ADL NCI Moderate impairment in attention or decreased level of concentration; limiting instrumental ADL CTCAE_v5 Grade 2 Concentration Impairment, CTCAE PT NCI Grade 2 Concentration impairment PT CTCAE_v5 ctcae5:C144588 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Conduction Disorder, CTCAE Grade 2 Conduction disorder 10010276 C144588 Grade 2 Conduction disorder Grade 2 Conduction disorder Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Conduction Disorder, CTCAE PT NCI Grade 2 Conduction disorder PT CTCAE_v5 ctcae5:C144589 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Grade 2 Congenital, familial and genetic disorders - Other, specify 10010331 C144589 Grade 2 Congenital, familial and genetic disorders - Other, specify Grade 2 Congenital, familial and genetic disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Grade 2 Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C144590 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Conjunctivitis Infective, CTCAE Grade 2 Conjunctivitis infective 10010742 C144590 Grade 2 Conjunctivitis infective Grade 2 Conjunctivitis infective Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Conjunctivitis Infective, CTCAE PT NCI Grade 2 Conjunctivitis infective PT CTCAE_v5 ctcae5:C144591 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Conjunctivitis Grade 2 Conjunctivitis, CTCAE 10010741 C144591 Grade 2 Conjunctivitis Grade 2 Conjunctivitis Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Conjunctivitis PT CTCAE_v5 Grade 2 Conjunctivitis, CTCAE PT NCI ctcae5:C144592 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Corneal Infection, CTCAE Grade 2 Corneal infection 10061788 C144592 Grade 2 Corneal infection Grade 2 Corneal infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Corneal Infection, CTCAE PT NCI Grade 2 Corneal infection PT CTCAE_v5 ctcae5:C144593 >2.5 x ULN-5 x ULN >2.5 x ULN-5 x ULN Grade 2 CPK Increased, CTCAE Grade 2 CPK increased 10011268 C144593 Grade 2 CPK increased Grade 2 CPK increased >2.5 x ULN-5 x ULN NCI >2.5 x ULN-5 x ULN CTCAE_v5 Grade 2 CPK Increased, CTCAE PT NCI Grade 2 CPK increased PT CTCAE_v5 ctcae5:C144594 >1.5-3.0 x baseline; >1.5-3.0 x ULN >1.5-3.0 x baseline; >1.5-3.0 x ULN Grade 2 Creatinine Increased, CTCAE Grade 2 Creatinine increased 10011368 C144594 Grade 2 Creatinine increased Grade 2 Creatinine increased >1.5-3.0 x baseline; >1.5-3.0 x ULN NCI >1.5-3.0 x baseline; >1.5-3.0 x ULN CTCAE_v5 Grade 2 Creatinine Increased, CTCAE PT NCI Grade 2 Creatinine increased PT CTCAE_v5 ctcae5:C144595 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Cushingoid Grade 2 Cushingoid, CTCAE 10011655 C144595 Grade 2 Cushingoid Grade 2 Cushingoid Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Cushingoid PT CTCAE_v5 Grade 2 Cushingoid, CTCAE PT NCI ctcae5:C144596 Present Present Grade 2 Cyanosis Grade 2 Cyanosis, CTCAE 10011703 C144596 Grade 2 Cyanosis Grade 2 Cyanosis Present NCI Present CTCAE_v5 Grade 2 Cyanosis PT CTCAE_v5 Grade 2 Cyanosis, CTCAE PT NCI ctcae5:C144597 Moderate hematuria; moderate increase in frequency, urgency, dysuria, nocturia or incontinence; urinary catheter placement or bladder irrigation indicated; limiting instrumental ADL Moderate hematuria; moderate increase in frequency, urgency, dysuria, nocturia or incontinence; urinary catheter placement or bladder irrigation indicated; limiting instrumental ADL Grade 2 Cystitis Noninfective, CTCAE Grade 2 Cystitis noninfective 10063057 C144597 Grade 2 Cystitis noninfective Grade 2 Cystitis noninfective Moderate hematuria; moderate increase in frequency, urgency, dysuria, nocturia or incontinence; urinary catheter placement or bladder irrigation indicated; limiting instrumental ADL NCI Moderate hematuria; moderate increase in frequency, urgency, dysuria, nocturia or incontinence; urinary catheter placement or bladder irrigation indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Cystitis Noninfective, CTCAE PT NCI Grade 2 Cystitis noninfective PT CTCAE_v5 ctcae5:C144598 Hypotension responding to fluids; hypoxia responding to <40% O2 Hypotension responding to fluids; hypoxia responding to <40% O2 Grade 2 Cytokine Release Syndrome, CTCAE Grade 2 Cytokine release syndrome 10052015 C144598 Grade 2 Cytokine release syndrome Grade 2 Cytokine release syndrome Hypotension responding to fluids; hypoxia responding to <40% O2 NCI Hypotension responding to fluids; hypoxia responding to <40% O2 CTCAE_v5 Grade 2 Cytokine Release Syndrome, CTCAE PT NCI Grade 2 Cytokine release syndrome PT CTCAE_v5 ctcae5:C144599 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Cytomegalovirus Infection Reactivation, CTCAE Grade 2 Cytomegalovirus infection reactivation 10058666 C144599 Grade 2 Cytomegalovirus infection reactivation Grade 2 Cytomegalovirus infection reactivation Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Grade 2 Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C144600 Delay in achieving orgasm adversely affecting relationship Delay in achieving orgasm adversely affecting relationship Grade 2 Delayed Orgasm, CTCAE Grade 2 Delayed orgasm 10057066 C144600 Grade 2 Delayed orgasm Grade 2 Delayed orgasm Delay in achieving orgasm adversely affecting relationship NCI Delay in achieving orgasm adversely affecting relationship CTCAE_v5 Grade 2 Delayed Orgasm, CTCAE PT NCI Grade 2 Delayed orgasm PT CTCAE_v5 ctcae5:C144601 Moderate and acute confusional state; limiting instrumental ADL Moderate and acute confusional state; limiting instrumental ADL Grade 2 Delirium Grade 2 Delirium, CTCAE 10012218 C144601 Grade 2 Delirium Grade 2 Delirium Moderate and acute confusional state; limiting instrumental ADL NCI Moderate and acute confusional state; limiting instrumental ADL CTCAE_v5 Grade 2 Delirium PT CTCAE_v5 Grade 2 Delirium, CTCAE PT NCI ctcae5:C144602 Moderate delusional symptoms Moderate delusional symptoms Grade 2 Delusions Grade 2 Delusions, CTCAE 10012260 C144602 Grade 2 Delusions Grade 2 Delusions Moderate delusional symptoms NCI Moderate delusional symptoms CTCAE_v5 Grade 2 Delusions PT CTCAE_v5 Grade 2 Delusions, CTCAE PT NCI ctcae5:C144603 Dental caries involving the root Dental caries involving the root Grade 2 Dental Caries, CTCAE Grade 2 Dental caries 10012318 C144603 Grade 2 Dental caries Grade 2 Dental caries Dental caries involving the root NCI Dental caries involving the root CTCAE_v5 Grade 2 Dental Caries, CTCAE PT NCI Grade 2 Dental caries PT CTCAE_v5 ctcae5:C144604 Sedation; slow response to stimuli; limiting instrumental ADL Sedation; slow response to stimuli; limiting instrumental ADL Grade 2 Depressed Level of Consciousness, CTCAE Grade 2 Depressed level of consciousness 10012373 C144604 Grade 2 Depressed level of consciousness Grade 2 Depressed level of consciousness Sedation; slow response to stimuli; limiting instrumental ADL NCI Sedation; slow response to stimuli; limiting instrumental ADL CTCAE_v5 Grade 2 Depressed Level of Consciousness, CTCAE PT NCI Grade 2 Depressed level of consciousness PT CTCAE_v5 ctcae5:C144605 Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema Grade 2 Dermatitis Radiation, CTCAE Grade 2 Dermatitis radiation 10061103 C144605 Grade 2 Dermatitis radiation Grade 2 Dermatitis radiation Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema NCI Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema CTCAE_v5 Grade 2 Dermatitis Radiation, CTCAE PT NCI Grade 2 Dermatitis radiation PT CTCAE_v5 ctcae5:C144606 Oral intervention indicated (e.g., antibiotic, antifungal) Oral intervention indicated (e.g., antibiotic, antifungal) Grade 2 Device Related Infection, CTCAE Grade 2 Device related infection 10064687 C144606 Grade 2 Device related infection Grade 2 Device related infection Oral intervention indicated (e.g., antibiotic, antifungal) NCI Oral intervention indicated (e.g., antibiotic, antifungal) CTCAE_v5 Grade 2 Device Related Infection, CTCAE PT NCI Grade 2 Device related infection PT CTCAE_v5 ctcae5:C144607 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Dry Eye, CTCAE Grade 2 Dry eye 10013774 C144607 Grade 2 Dry eye Grade 2 Dry eye Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Dry Eye, CTCAE PT NCI Grade 2 Dry eye PT CTCAE_v5 ctcae5:C144608 Moderate symptoms; oral intake alterations (e.g., copious water, other lubricants, diet limited to purees and/or soft, moist foods); unstimulated saliva 0.1 to 0.2 ml/min Moderate symptoms; oral intake alterations (e.g., copious water, other lubricants, diet limited to purees and/or soft, moist foods); unstimulated saliva 0.1 to 0.2 ml/min Grade 2 Dry Mouth, CTCAE Grade 2 Dry mouth 10013781 C144608 Grade 2 Dry mouth Grade 2 Dry mouth Moderate symptoms; oral intake alterations (e.g., copious water, other lubricants, diet limited to purees and/or soft, moist foods); unstimulated saliva 0.1 to 0.2 ml/min NCI Moderate symptoms; oral intake alterations (e.g., copious water, other lubricants, diet limited to purees and/or soft, moist foods); unstimulated saliva 0.1 to 0.2 ml/min CTCAE_v5 Grade 2 Dry Mouth, CTCAE PT NCI Grade 2 Dry mouth PT CTCAE_v5 ctcae5:C144610 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Duodenal Hemorrhage, CTCAE Grade 2 Duodenal hemorrhage 10055242 C144610 Grade 2 Duodenal hemorrhage Grade 2 Duodenal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Duodenal Hemorrhage, CTCAE PT NCI Grade 2 Duodenal hemorrhage PT CTCAE_v5 ctcae5:C144611 Moderate symptoms; medical intervention indicated (e.g., oral antibiotics) Moderate symptoms; medical intervention indicated (e.g., oral antibiotics) Grade 2 Duodenal Infection, CTCAE Grade 2 Duodenal infection 10065752 C144611 Grade 2 Duodenal infection Grade 2 Duodenal infection Moderate symptoms; medical intervention indicated (e.g., oral antibiotics) NCI Moderate symptoms; medical intervention indicated (e.g., oral antibiotics) CTCAE_v5 Grade 2 Duodenal Infection, CTCAE PT NCI Grade 2 Duodenal infection PT CTCAE_v5 ctcae5:C144612 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Duodenal Obstruction, CTCAE Grade 2 Duodenal obstruction 10013830 C144612 Grade 2 Duodenal obstruction Grade 2 Duodenal obstruction Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Duodenal Obstruction, CTCAE PT NCI Grade 2 Duodenal obstruction PT CTCAE_v5 ctcae5:C144613 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Duodenal Perforation, CTCAE Grade 2 Duodenal perforation 10013832 C144613 Grade 2 Duodenal perforation Grade 2 Duodenal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Duodenal Perforation, CTCAE PT NCI Grade 2 Duodenal perforation PT CTCAE_v5 ctcae5:C144614 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Duodenal Stenosis, CTCAE Grade 2 Duodenal stenosis 10050094 C144614 Grade 2 Duodenal stenosis Grade 2 Duodenal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Duodenal Stenosis, CTCAE PT NCI Grade 2 Duodenal stenosis PT CTCAE_v5 ctcae5:C144615 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Duodenal Ulcer, CTCAE Grade 2 Duodenal ulcer 10013836 C144615 Grade 2 Duodenal ulcer Grade 2 Duodenal ulcer Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Duodenal Ulcer, CTCAE PT NCI Grade 2 Duodenal ulcer PT CTCAE_v5 ctcae5:C144616 Moderate impairment of articulation or slurred speech Moderate impairment of articulation or slurred speech Grade 2 Dysarthria Grade 2 Dysarthria, CTCAE 10013887 C144616 Grade 2 Dysarthria Grade 2 Dysarthria Moderate impairment of articulation or slurred speech NCI Moderate impairment of articulation or slurred speech CTCAE_v5 Grade 2 Dysarthria PT CTCAE_v5 Grade 2 Dysarthria, CTCAE PT NCI ctcae5:C144617 Moderate sensory alteration; limiting instrumental ADL Moderate sensory alteration; limiting instrumental ADL Grade 2 Dysesthesia Grade 2 Dysesthesia, CTCAE 10062872 C144617 Grade 2 Dysesthesia Grade 2 Dysesthesia Moderate sensory alteration; limiting instrumental ADL NCI Moderate sensory alteration; limiting instrumental ADL CTCAE_v5 Grade 2 Dysesthesia PT CTCAE_v5 Grade 2 Dysesthesia, CTCAE PT NCI ctcae5:C144618 Altered taste with change in diet (e.g., oral supplements); noxious or unpleasant taste; loss of taste Altered taste with change in diet (e.g., oral supplements); noxious or unpleasant taste; loss of taste Grade 2 Dysgeusia Grade 2 Dysgeusia, CTCAE 10013911 C144618 Grade 2 Dysgeusia Grade 2 Dysgeusia Altered taste with change in diet (e.g., oral supplements); noxious or unpleasant taste; loss of taste NCI Altered taste with change in diet (e.g., oral supplements); noxious or unpleasant taste; loss of taste CTCAE_v5 Grade 2 Dysgeusia PT CTCAE_v5 Grade 2 Dysgeusia, CTCAE PT NCI ctcae5:C144619 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Dysmenorrhea Grade 2 Dysmenorrhea, CTCAE 10013934 C144619 Grade 2 Dysmenorrhea Grade 2 Dysmenorrhea Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Dysmenorrhea PT CTCAE_v5 Grade 2 Dysmenorrhea, CTCAE PT NCI ctcae5:C144620 Moderate discomfort or pain associated with vaginal penetration; discomfort or pain partially relieved with use of vaginal lubricants or estrogen Moderate discomfort or pain associated with vaginal penetration; discomfort or pain partially relieved with use of vaginal lubricants or estrogen Grade 2 Dyspareunia Grade 2 Dyspareunia, CTCAE 10013941 C144620 Grade 2 Dyspareunia Grade 2 Dyspareunia Moderate discomfort or pain associated with vaginal penetration; discomfort or pain partially relieved with use of vaginal lubricants or estrogen NCI Moderate discomfort or pain associated with vaginal penetration; discomfort or pain partially relieved with use of vaginal lubricants or estrogen CTCAE_v5 Grade 2 Dyspareunia PT CTCAE_v5 Grade 2 Dyspareunia, CTCAE PT NCI ctcae5:C144621 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Dyspepsia Grade 2 Dyspepsia, CTCAE 10013946 C144621 Grade 2 Dyspepsia Grade 2 Dyspepsia Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Dyspepsia PT CTCAE_v5 Grade 2 Dyspepsia, CTCAE PT NCI ctcae5:C144622 Moderate receptive or expressive characteristics; impairing ability to communicate spontaneously Moderate receptive or expressive characteristics; impairing ability to communicate spontaneously Grade 2 Dysphasia Grade 2 Dysphasia, CTCAE 10013951 C144622 Grade 2 Dysphasia Grade 2 Dysphasia Moderate receptive or expressive characteristics; impairing ability to communicate spontaneously NCI Moderate receptive or expressive characteristics; impairing ability to communicate spontaneously CTCAE_v5 Grade 2 Dysphasia PT CTCAE_v5 Grade 2 Dysphasia, CTCAE PT NCI ctcae5:C144623 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Ear and Labyrinth Disorders - Other, Specify, CTCAE Grade 2 Ear and labyrinth disorders - Other, specify 10013993 C144623 Grade 2 Ear and labyrinth disorders - Other, specify Grade 2 Ear and labyrinth disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Grade 2 Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C144624 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Ear Pain, CTCAE Grade 2 Ear pain 10014020 C144624 Grade 2 Ear pain Grade 2 Ear pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Ear Pain, CTCAE PT NCI Grade 2 Ear pain PT CTCAE_v5 ctcae5:C144625 Moderate; topical or oral intervention indicated; additional medical intervention over baseline indicated Moderate; topical or oral intervention indicated; additional medical intervention over baseline indicated Grade 2 Eczema Grade 2 Eczema, CTCAE 10014184 C144625 Grade 2 Eczema Grade 2 Eczema Moderate; topical or oral intervention indicated; additional medical intervention over baseline indicated NCI Moderate; topical or oral intervention indicated; additional medical intervention over baseline indicated CTCAE_v5 Grade 2 Eczema PT CTCAE_v5 Grade 2 Eczema, CTCAE PT NCI ctcae5:C144626 Moderate localized facial edema; limiting instrumental ADL Moderate localized facial edema; limiting instrumental ADL Grade 2 Edema Face, CTCAE Grade 2 Edema face 10014222 C144626 Grade 2 Edema face Grade 2 Edema face Moderate localized facial edema; limiting instrumental ADL NCI Moderate localized facial edema; limiting instrumental ADL CTCAE_v5 Grade 2 Edema Face, CTCAE PT NCI Grade 2 Edema face PT CTCAE_v5 ctcae5:C144627 >10-30% inter-limb discrepancy in volume or circumference at point of greatest visible difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL >10-30% inter-limb discrepancy in volume or circumference at point of greatest visible difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL Grade 2 Edema Limbs, CTCAE Grade 2 Edema limbs 10050068 C144627 Grade 2 Edema limbs Grade 2 Edema limbs >10-30% inter-limb discrepancy in volume or circumference at point of greatest visible difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL NCI >10-30% inter-limb discrepancy in volume or circumference at point of greatest visible difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL CTCAE_v5 Grade 2 Edema Limbs, CTCAE PT NCI Grade 2 Edema limbs PT CTCAE_v5 ctcae5:C144628 Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL Grade 2 Edema Trunk, CTCAE Grade 2 Edema trunk 10058720 C144628 Grade 2 Edema trunk Grade 2 Edema trunk Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL NCI Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour; limiting instrumental ADL CTCAE_v5 Grade 2 Edema Trunk, CTCAE PT NCI Grade 2 Edema trunk PT CTCAE_v5 ctcae5:C144629 Anejaculation or retrograde ejaculation Anejaculation or retrograde ejaculation Grade 2 Ejaculation Disorder, CTCAE Grade 2 Ejaculation disorder 10014326 C144629 Grade 2 Ejaculation disorder Grade 2 Ejaculation disorder Anejaculation or retrograde ejaculation NCI Anejaculation or retrograde ejaculation CTCAE_v5 Grade 2 Ejaculation Disorder, CTCAE PT NCI Grade 2 Ejaculation disorder PT CTCAE_v5 ctcae5:C144630 Resting ejection fraction (EF) 50-40%; 10-19% drop from baseline Resting ejection fraction (EF) 50-40%; 10-19% drop from baseline Grade 2 Ejection Fraction Decreased, CTCAE Grade 2 Ejection fraction decreased 10050528 C144630 Grade 2 Ejection fraction decreased Grade 2 Ejection fraction decreased Resting ejection fraction (EF) 50-40%; 10-19% drop from baseline NCI Resting ejection fraction (EF) 50-40%; 10-19% drop from baseline CTCAE_v5 Grade 2 Ejection Fraction Decreased, CTCAE PT NCI Grade 2 Ejection fraction decreased PT CTCAE_v5 ctcae5:C144631 Average QTc 481-500 ms Average QTc 481-500 ms Grade 2 Electrocardiogram QT Corrected Interval Prolonged, CTCAE Grade 2 Electrocardiogram QT corrected interval prolonged 10014383 C144631 Grade 2 Electrocardiogram QT corrected interval prolonged Grade 2 Electrocardiogram QT corrected interval prolonged Average QTc 481-500 ms NCI Average QTc 481-500 ms CTCAE_v5 Grade 2 Electrocardiogram QT Corrected Interval Prolonged, CTCAE PT NCI Grade 2 Electrocardiogram QT corrected interval prolonged PT CTCAE_v5 ctcae5:C144632 Nonspecific ST segment change Nonspecific ST segment change Grade 2 Electrocardiogram T Wave Abnormal, CTCAE Grade 2 Electrocardiogram T wave abnormal 10050380 C144632 Grade 2 Electrocardiogram T wave abnormal Grade 2 Electrocardiogram T wave abnormal Nonspecific ST segment change NCI Nonspecific ST segment change CTCAE_v5 Grade 2 Electrocardiogram T Wave Abnormal, CTCAE PT NCI Grade 2 Electrocardiogram T wave abnormal PT CTCAE_v5 ctcae5:C144633 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Endocrine Disorders - Other, Specify, CTCAE Grade 2 Endocrine disorders - Other, specify 10014698 C144633 Grade 2 Endocrine disorders - Other, specify Grade 2 Endocrine disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Endocrine Disorders - Other, Specify, CTCAE PT NCI Grade 2 Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C144634 Local intervention indicated Local intervention indicated Grade 2 Endophthalmitis Grade 2 Endophthalmitis, CTCAE 10014801 C144634 Grade 2 Endophthalmitis Grade 2 Endophthalmitis Local intervention indicated NCI Local intervention indicated CTCAE_v5 Grade 2 Endophthalmitis PT CTCAE_v5 Grade 2 Endophthalmitis, CTCAE PT NCI ctcae5:C144635 Passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Enterocolitis Infectious, CTCAE Grade 2 Enterocolitis infectious 10058838 C144635 Grade 2 Enterocolitis infectious Grade 2 Enterocolitis infectious Passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Passage of >3 unformed stools per 24 hrs or duration of illness >48 hrs; moderate abdominal pain; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Enterocolitis Infectious, CTCAE PT NCI Grade 2 Enterocolitis infectious PT CTCAE_v5 ctcae5:C144636 Abdominal pain; mucus or blood in stool Abdominal pain; mucus or blood in stool Grade 2 Enterocolitis Grade 2 Enterocolitis, CTCAE 10014893 C144636 Grade 2 Enterocolitis Grade 2 Enterocolitis Abdominal pain; mucus or blood in stool NCI Abdominal pain; mucus or blood in stool CTCAE_v5 Grade 2 Enterocolitis PT CTCAE_v5 Grade 2 Enterocolitis, CTCAE PT NCI ctcae5:C144637 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Enterovesical Fistula, CTCAE Grade 2 Enterovesical fistula 10062570 C144637 Grade 2 Enterovesical fistula Grade 2 Enterovesical fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Enterovesical Fistula, CTCAE PT NCI Grade 2 Enterovesical fistula PT CTCAE_v5 ctcae5:C144638 Moderate symptoms; medical intervention indicated (e.g., nasal packing, cauterization; topical vasoconstrictors) Moderate symptoms; medical intervention indicated (e.g., nasal packing, cauterization; topical vasoconstrictors) Grade 2 Epistaxis Grade 2 Epistaxis, CTCAE 10015090 C144638 Grade 2 Epistaxis Grade 2 Epistaxis Moderate symptoms; medical intervention indicated (e.g., nasal packing, cauterization; topical vasoconstrictors) NCI Moderate symptoms; medical intervention indicated (e.g., nasal packing, cauterization; topical vasoconstrictors) CTCAE_v5 Grade 2 Epistaxis PT CTCAE_v5 Grade 2 Epistaxis, CTCAE PT NCI ctcae5:C144639 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Epstein-Barr Virus Infection Reactivation, CTCAE Grade 2 Epstein-Barr virus infection reactivation 10015109 C144639 Grade 2 Epstein-Barr virus infection reactivation Grade 2 Epstein-Barr virus infection reactivation Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Grade 2 Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C144640 Target lesions covering 10-30% BSA and associated with skin tenderness Target lesions covering 10-30% BSA and associated with skin tenderness Grade 2 Erythema Multiforme, CTCAE Grade 2 Erythema multiforme 10015218 C144640 Grade 2 Erythema multiforme Grade 2 Erythema multiforme Target lesions covering 10-30% BSA and associated with skin tenderness NCI Target lesions covering 10-30% BSA and associated with skin tenderness CTCAE_v5 Grade 2 Erythema Multiforme, CTCAE PT NCI Grade 2 Erythema multiforme PT CTCAE_v5 ctcae5:C144641 Erythema covering >90% BSA without associated symptoms; limiting instrumental ADL Erythema covering >90% BSA without associated symptoms; limiting instrumental ADL Grade 2 Erythroderma Grade 2 Erythroderma, CTCAE 10015277 C144641 Grade 2 Erythroderma Grade 2 Erythroderma Erythema covering >90% BSA without associated symptoms; limiting instrumental ADL NCI Erythema covering >90% BSA without associated symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Erythroderma PT CTCAE_v5 Grade 2 Erythroderma, CTCAE PT NCI ctcae5:C144642 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Esophageal Anastomotic Leak, CTCAE Grade 2 Esophageal anastomotic leak 10065961 C144642 Grade 2 Esophageal anastomotic leak Grade 2 Esophageal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Esophageal Anastomotic Leak, CTCAE PT NCI Grade 2 Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C144644 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Esophageal Hemorrhage, CTCAE Grade 2 Esophageal hemorrhage 10015384 C144644 Grade 2 Esophageal hemorrhage Grade 2 Esophageal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Esophageal Hemorrhage, CTCAE PT NCI Grade 2 Esophageal hemorrhage PT CTCAE_v5 ctcae5:C144645 Local intervention indicated (e.g., oral antibiotic, antifungal, antiviral) Local intervention indicated (e.g., oral antibiotic, antifungal, antiviral) Grade 2 Esophageal Infection, CTCAE Grade 2 Esophageal infection 10058804 C144645 Grade 2 Esophageal infection Grade 2 Esophageal infection Local intervention indicated (e.g., oral antibiotic, antifungal, antiviral) NCI Local intervention indicated (e.g., oral antibiotic, antifungal, antiviral) CTCAE_v5 Grade 2 Esophageal Infection, CTCAE PT NCI Grade 2 Esophageal infection PT CTCAE_v5 ctcae5:C144646 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Esophageal Obstruction, CTCAE Grade 2 Esophageal obstruction 10015387 C144646 Grade 2 Esophageal obstruction Grade 2 Esophageal obstruction Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Esophageal Obstruction, CTCAE PT NCI Grade 2 Esophageal obstruction PT CTCAE_v5 ctcae5:C144647 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Esophageal Pain, CTCAE Grade 2 Esophageal pain 10015388 C144647 Grade 2 Esophageal pain Grade 2 Esophageal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Esophageal Pain, CTCAE PT NCI Grade 2 Esophageal pain PT CTCAE_v5 ctcae5:C144648 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Esophageal Perforation, CTCAE Grade 2 Esophageal perforation 10055472 C144648 Grade 2 Esophageal perforation Grade 2 Esophageal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Esophageal Perforation, CTCAE PT NCI Grade 2 Esophageal perforation PT CTCAE_v5 ctcae5:C144649 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Esophageal Stenosis, CTCAE Grade 2 Esophageal stenosis 10015448 C144649 Grade 2 Esophageal stenosis Grade 2 Esophageal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Esophageal Stenosis, CTCAE PT NCI Grade 2 Esophageal stenosis PT CTCAE_v5 ctcae5:C144650 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Esophageal Ulcer, CTCAE Grade 2 Esophageal ulcer 10015451 C144650 Grade 2 Esophageal ulcer Grade 2 Esophageal ulcer Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Esophageal Ulcer, CTCAE PT NCI Grade 2 Esophageal ulcer PT CTCAE_v5 ctcae5:C144651 Unilateral paresis without double vision Unilateral paresis without double vision Grade 2 Extraocular Muscle Paresis, CTCAE Grade 2 Extraocular muscle paresis 10015829 C144651 Grade 2 Extraocular muscle paresis Grade 2 Extraocular muscle paresis Unilateral paresis without double vision NCI Unilateral paresis without double vision CTCAE_v5 Grade 2 Extraocular Muscle Paresis, CTCAE PT NCI Grade 2 Extraocular muscle paresis PT CTCAE_v5 ctcae5:C144652 Moderate involuntary movements; limiting instrumental ADL Moderate involuntary movements; limiting instrumental ADL Grade 2 Extrapyramidal Disorder, CTCAE Grade 2 Extrapyramidal disorder 10015832 C144652 Grade 2 Extrapyramidal disorder Grade 2 Extrapyramidal disorder Moderate involuntary movements; limiting instrumental ADL NCI Moderate involuntary movements; limiting instrumental ADL CTCAE_v5 Grade 2 Extrapyramidal Disorder, CTCAE PT NCI Grade 2 Extrapyramidal disorder PT CTCAE_v5 ctcae5:C144653 Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL; best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL; best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline Grade 2 Eye Disorders - Other, Specify, CTCAE Grade 2 Eye disorders - Other, specify 10015919 C144653 Grade 2 Eye disorders - Other, specify Grade 2 Eye disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL; best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline NCI Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL; best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline CTCAE_v5 Grade 2 Eye Disorders - Other, Specify, CTCAE PT NCI Grade 2 Eye disorders - Other, specify PT CTCAE_v5 ctcae5:C144654 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Eye Infection, CTCAE Grade 2 Eye infection 10015929 C144654 Grade 2 Eye infection Grade 2 Eye infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Eye Infection, CTCAE PT NCI Grade 2 Eye infection PT CTCAE_v5 ctcae5:C144655 Symptomatic; nonoperative intervention indicated; limiting instrumental ADL Symptomatic; nonoperative intervention indicated; limiting instrumental ADL Grade 2 Eyelid Function Disorder, CTCAE Grade 2 Eyelid function disorder 10061145 C144655 Grade 2 Eyelid function disorder Grade 2 Eyelid function disorder Symptomatic; nonoperative intervention indicated; limiting instrumental ADL NCI Symptomatic; nonoperative intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Eyelid Function Disorder, CTCAE PT NCI Grade 2 Eyelid function disorder PT CTCAE_v5 ctcae5:C144656 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Facial Muscle Weakness, CTCAE Grade 2 Facial muscle weakness 10051272 C144656 Grade 2 Facial muscle weakness Grade 2 Facial muscle weakness Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Facial Muscle Weakness, CTCAE PT NCI Grade 2 Facial muscle weakness PT CTCAE_v5 ctcae5:C144657 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Facial Nerve Disorder, CTCAE Grade 2 Facial nerve disorder 10061457 C144657 Grade 2 Facial nerve disorder Grade 2 Facial nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Facial Nerve Disorder, CTCAE PT NCI Grade 2 Facial nerve disorder PT CTCAE_v5 ctcae5:C144658 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Facial Pain, CTCAE Grade 2 Facial pain 10016059 C144658 Grade 2 Facial pain Grade 2 Facial pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Facial Pain, CTCAE PT NCI Grade 2 Facial pain PT CTCAE_v5 ctcae5:C144659 Symptomatic; noninvasive intervention indicated Symptomatic; noninvasive intervention indicated Grade 2 Fall Grade 2 Fall, CTCAE 10016173 C144659 Grade 2 Fall Grade 2 Fall Symptomatic; noninvasive intervention indicated NCI Symptomatic; noninvasive intervention indicated CTCAE_v5 Grade 2 Fall PT CTCAE_v5 Grade 2 Fall, CTCAE PT NCI ctcae5:C144660 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Fallopian Tube Anastomotic Leak, CTCAE Grade 2 Fallopian tube anastomotic leak 10065788 C144660 Grade 2 Fallopian tube anastomotic leak Grade 2 Fallopian tube anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Grade 2 Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C144661 Covering 10-30% BSA and associated with erythema or tenderness; limiting instrumental ADL Covering 10-30% BSA and associated with erythema or tenderness; limiting instrumental ADL Grade 2 Fat Atrophy, CTCAE Grade 2 Fat atrophy 10016241 C144661 Grade 2 Fat atrophy Grade 2 Fat atrophy Covering 10-30% BSA and associated with erythema or tenderness; limiting instrumental ADL NCI Covering 10-30% BSA and associated with erythema or tenderness; limiting instrumental ADL CTCAE_v5 Grade 2 Fat Atrophy, CTCAE PT NCI Grade 2 Fat atrophy PT CTCAE_v5 ctcae5:C144662 Daily use of pads required Daily use of pads required Grade 2 Fecal Incontinence, CTCAE Grade 2 Fecal incontinence 10016296 C144662 Grade 2 Fecal incontinence Grade 2 Fecal incontinence Daily use of pads required NCI Daily use of pads required CTCAE_v5 Grade 2 Fecal Incontinence, CTCAE PT NCI Grade 2 Fecal incontinence PT CTCAE_v5 ctcae5:C144663 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Feminization Acquired, CTCAE Grade 2 Feminization acquired 10054382 C144663 Grade 2 Feminization acquired Grade 2 Feminization acquired Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Feminization Acquired, CTCAE PT NCI Grade 2 Feminization acquired PT CTCAE_v5 ctcae5:C144664 <10% percentile of weight for gestational age <10% percentile of weight for gestational age Grade 2 Fetal Growth Retardation, CTCAE Grade 2 Fetal growth retardation 10054746 C144664 Grade 2 Fetal growth retardation Grade 2 Fetal growth retardation <10% percentile of weight for gestational age NCI <10% percentile of weight for gestational age CTCAE_v5 Grade 2 Fetal Growth Retardation, CTCAE PT NCI Grade 2 Fetal growth retardation PT CTCAE_v5 ctcae5:C144665 >39.0-40.0 degrees C (102.3-104.0 degrees F) >39.0-40.0 degrees C (102.3-104.0 degrees F) Grade 2 Fever Grade 2 Fever, CTCAE 10016558 C144665 Grade 2 Fever Grade 2 Fever >39.0-40.0 degrees C (102.3-104.0 degrees F) NCI >39.0-40.0 degrees C (102.3-104.0 degrees F) CTCAE_v5 Grade 2 Fever PT CTCAE_v5 Grade 2 Fever, CTCAE PT NCI ctcae5:C144666 <0.75-0.5 x LLN; if abnormal, 25-<50% decrease from baseline <0.75-0.5 x LLN; if abnormal, 25-<50% decrease from baseline Grade 2 Fibrinogen Decreased, CTCAE Grade 2 Fibrinogen decreased 10016596 C144666 Grade 2 Fibrinogen decreased Grade 2 Fibrinogen decreased <0.75-0.5 x LLN; if abnormal, 25-<50% decrease from baseline NCI <0.75-0.5 x LLN; if abnormal, 25-<50% decrease from baseline CTCAE_v5 Grade 2 Fibrinogen Decreased, CTCAE PT NCI Grade 2 Fibrinogen decreased PT CTCAE_v5 ctcae5:C144667 Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Grade 2 Fibrosis Deep Connective Tissue, CTCAE Grade 2 Fibrosis deep connective tissue 10065799 C144667 Grade 2 Fibrosis deep connective tissue Grade 2 Fibrosis deep connective tissue Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL NCI Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL CTCAE_v5 Grade 2 Fibrosis Deep Connective Tissue, CTCAE PT NCI Grade 2 Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C144668 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Flank Pain, CTCAE Grade 2 Flank pain 10016750 C144668 Grade 2 Flank pain Grade 2 Flank pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Flank Pain, CTCAE PT NCI Grade 2 Flank pain PT CTCAE_v5 ctcae5:C144669 Limiting instrumental ADL Limiting instrumental ADL Grade 2 Flashing Lights, CTCAE Grade 2 Flashing lights 10016757 C144669 Grade 2 Flashing lights Grade 2 Flashing lights Limiting instrumental ADL NCI Limiting instrumental ADL CTCAE_v5 Grade 2 Flashing Lights, CTCAE PT NCI Grade 2 Flashing lights PT CTCAE_v5 ctcae5:C144670 Limiting instrumental ADL Limiting instrumental ADL Grade 2 Floaters Grade 2 Floaters, CTCAE 10016778 C144670 Grade 2 Floaters Grade 2 Floaters Limiting instrumental ADL NCI Limiting instrumental ADL CTCAE_v5 Grade 2 Floaters PT CTCAE_v5 Grade 2 Floaters, CTCAE PT NCI ctcae5:C144671 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Flu Like Symptoms, CTCAE Grade 2 Flu like symptoms 10016791 C144671 Grade 2 Flu like symptoms Grade 2 Flu like symptoms Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Flu Like Symptoms, CTCAE PT NCI Grade 2 Flu like symptoms PT CTCAE_v5 ctcae5:C144672 Covering 10-30% of the body surface area; topical intervention initiated Covering 10-30% of the body surface area; topical intervention initiated Grade 2 Folliculitis Grade 2 Folliculitis, CTCAE 10016936 C144672 Grade 2 Folliculitis Grade 2 Folliculitis Covering 10-30% of the body surface area; topical intervention initiated NCI Covering 10-30% of the body surface area; topical intervention initiated CTCAE_v5 Grade 2 Folliculitis PT CTCAE_v5 Grade 2 Folliculitis, CTCAE PT NCI ctcae5:C144673 FEV1 60-69% FEV1 60-69% Grade 2 Forced Expiratory Volume Decreased, CTCAE Grade 2 Forced expiratory volume decreased 10016987 C144673 Grade 2 Forced expiratory volume decreased Grade 2 Forced expiratory volume decreased FEV1 60-69% NCI FEV1 60-69% CTCAE_v5 Grade 2 Forced Expiratory Volume Decreased, CTCAE PT NCI Grade 2 Forced expiratory volume decreased PT CTCAE_v5 ctcae5:C144674 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Fungemia Grade 2 Fungemia, CTCAE 10017544 C144674 Grade 2 Fungemia Grade 2 Fungemia Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Fungemia PT CTCAE_v5 Grade 2 Fungemia, CTCAE PT NCI ctcae5:C144675 Moderate change in gait (e.g., wide-based, limping or hobbling); assistive device indicated; limiting instrumental ADL Moderate change in gait (e.g., wide-based, limping or hobbling); assistive device indicated; limiting instrumental ADL Grade 2 Gait Disturbance, CTCAE Grade 2 Gait disturbance 10017577 C144675 Grade 2 Gait disturbance Grade 2 Gait disturbance Moderate change in gait (e.g., wide-based, limping or hobbling); assistive device indicated; limiting instrumental ADL NCI Moderate change in gait (e.g., wide-based, limping or hobbling); assistive device indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Gait Disturbance, CTCAE PT NCI Grade 2 Gait disturbance PT CTCAE_v5 ctcae5:C144676 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Gallbladder Infection, CTCAE Grade 2 Gallbladder infection 10062632 C144676 Grade 2 Gallbladder infection Grade 2 Gallbladder infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Gallbladder Infection, CTCAE PT NCI Grade 2 Gallbladder infection PT CTCAE_v5 ctcae5:C144677 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Gastric Anastomotic Leak, CTCAE Grade 2 Gastric anastomotic leak 10065893 C144677 Grade 2 Gastric anastomotic leak Grade 2 Gastric anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Gastric Anastomotic Leak, CTCAE PT NCI Grade 2 Gastric anastomotic leak PT CTCAE_v5 ctcae5:C144678 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Gastric Fistula, CTCAE Grade 2 Gastric fistula 10065713 C144678 Grade 2 Gastric fistula Grade 2 Gastric fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Gastric Fistula, CTCAE PT NCI Grade 2 Gastric fistula PT CTCAE_v5 ctcae5:C144679 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Gastric Hemorrhage, CTCAE Grade 2 Gastric hemorrhage 10017789 C144679 Grade 2 Gastric hemorrhage Grade 2 Gastric hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Gastric Hemorrhage, CTCAE PT NCI Grade 2 Gastric hemorrhage PT CTCAE_v5 ctcae5:C144680 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Gastric Perforation, CTCAE Grade 2 Gastric perforation 10017815 C144680 Grade 2 Gastric perforation Grade 2 Gastric perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Gastric Perforation, CTCAE PT NCI Grade 2 Gastric perforation PT CTCAE_v5 ctcae5:C144681 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Gastric Stenosis, CTCAE Grade 2 Gastric stenosis 10061970 C144681 Grade 2 Gastric stenosis Grade 2 Gastric stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Gastric Stenosis, CTCAE PT NCI Grade 2 Gastric stenosis PT CTCAE_v5 ctcae5:C144682 Symptomatic; altered GI function; medical intervention indicated; limiting instrumental ADL Symptomatic; altered GI function; medical intervention indicated; limiting instrumental ADL Grade 2 Gastric Ulcer, CTCAE Grade 2 Gastric ulcer 10017822 C144682 Grade 2 Gastric ulcer Grade 2 Gastric ulcer Symptomatic; altered GI function; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; altered GI function; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Gastric Ulcer, CTCAE PT NCI Grade 2 Gastric ulcer PT CTCAE_v5 ctcae5:C144683 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Gastroesophageal Reflux Disease, CTCAE Grade 2 Gastroesophageal reflux disease 10066874 C144683 Grade 2 Gastroesophageal reflux disease Grade 2 Gastroesophageal reflux disease Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Gastroesophageal Reflux Disease, CTCAE PT NCI Grade 2 Gastroesophageal reflux disease PT CTCAE_v5 ctcae5:C144684 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Gastrointestinal Anastomotic Leak, CTCAE Grade 2 Gastrointestinal anastomotic leak 10065879 C144684 Grade 2 Gastrointestinal anastomotic leak Grade 2 Gastrointestinal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Grade 2 Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C144685 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Gastrointestinal Disorders - Other, Specify, CTCAE Grade 2 Gastrointestinal disorders - Other, specify 10017947 C144685 Grade 2 Gastrointestinal disorders - Other, specify Grade 2 Gastrointestinal disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Grade 2 Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C144686 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Gastrointestinal Fistula, CTCAE Grade 2 Gastrointestinal fistula 10017877 C144686 Grade 2 Gastrointestinal fistula Grade 2 Gastrointestinal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Gastrointestinal Fistula, CTCAE PT NCI Grade 2 Gastrointestinal fistula PT CTCAE_v5 ctcae5:C144687 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Gastrointestinal Pain, CTCAE Grade 2 Gastrointestinal pain 10017999 C144687 Grade 2 Gastrointestinal pain Grade 2 Gastrointestinal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Gastrointestinal Pain, CTCAE PT NCI Grade 2 Gastrointestinal pain PT CTCAE_v5 ctcae5:C144688 Superficial necrosis; intervention not indicated Superficial necrosis; intervention not indicated Grade 2 Gastrointestinal Stoma Necrosis, CTCAE Grade 2 Gastrointestinal stoma necrosis 10065712 C144688 Grade 2 Gastrointestinal stoma necrosis Grade 2 Gastrointestinal stoma necrosis Superficial necrosis; intervention not indicated NCI Superficial necrosis; intervention not indicated CTCAE_v5 Grade 2 Gastrointestinal Stoma Necrosis, CTCAE PT NCI Grade 2 Gastrointestinal stoma necrosis PT CTCAE_v5 ctcae5:C144689 Moderate symptoms; able to maintain nutrition with dietary and lifestyle modifications; may need pharmacologic intervention Moderate symptoms; able to maintain nutrition with dietary and lifestyle modifications; may need pharmacologic intervention Grade 2 Gastroparesis Grade 2 Gastroparesis, CTCAE 10018043 C144689 Grade 2 Gastroparesis Grade 2 Gastroparesis Moderate symptoms; able to maintain nutrition with dietary and lifestyle modifications; may need pharmacologic intervention NCI Moderate symptoms; able to maintain nutrition with dietary and lifestyle modifications; may need pharmacologic intervention CTCAE_v5 Grade 2 Gastroparesis PT CTCAE_v5 Grade 2 Gastroparesis, CTCAE PT NCI ctcae5:C144690 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 General Disorders and Administration Site Conditions - Other, Specify, CTCAE Grade 2 General disorders and administration site conditions - Other, specify 10018065 C144690 Grade 2 General disorders and administration site conditions - Other, specify Grade 2 General disorders and administration site conditions - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI Grade 2 General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C144691 Interfering with instrumental ADLs; oral therapy initiated Interfering with instrumental ADLs; oral therapy initiated Grade 2 Generalized Edema, CTCAE Grade 2 Generalized edema 10018112 C144691 Grade 2 Generalized edema Grade 2 Generalized edema Interfering with instrumental ADLs; oral therapy initiated NCI Interfering with instrumental ADLs; oral therapy initiated CTCAE_v5 Grade 2 Generalized Edema, CTCAE PT NCI Grade 2 Generalized edema PT CTCAE_v5 ctcae5:C144692 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Generalized Muscle Weakness, CTCAE Grade 2 Generalized muscle weakness 10062572 C144692 Grade 2 Generalized muscle weakness Grade 2 Generalized muscle weakness Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Generalized Muscle Weakness, CTCAE PT NCI Grade 2 Generalized muscle weakness PT CTCAE_v5 ctcae5:C144693 Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour Grade 2 Genital Edema, CTCAE Grade 2 Genital edema 10018146 C144693 Grade 2 Genital edema Grade 2 Genital edema Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour NCI Readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent deviation from normal anatomic contour CTCAE_v5 Grade 2 Genital Edema, CTCAE PT NCI Grade 2 Genital edema PT CTCAE_v5 ctcae5:C144694 >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal Grade 2 GGT Increased, CTCAE Grade 2 GGT increased 10056910 C144694 Grade 2 GGT increased Grade 2 GGT increased >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal NCI >2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal CTCAE_v5 Grade 2 GGT Increased, CTCAE PT NCI Grade 2 GGT increased PT CTCAE_v5 ctcae5:C144695 Moderate pain interfering with oral intake Moderate pain interfering with oral intake Grade 2 Gingival Pain, CTCAE Grade 2 Gingival pain 10018286 C144695 Grade 2 Gingival pain Grade 2 Gingival pain Moderate pain interfering with oral intake NCI Moderate pain interfering with oral intake CTCAE_v5 Grade 2 Gingival Pain, CTCAE PT NCI Grade 2 Gingival pain PT CTCAE_v5 ctcae5:C144696 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Glossopharyngeal Nerve Disorder, CTCAE Grade 2 Glossopharyngeal nerve disorder 10061185 C144696 Grade 2 Glossopharyngeal nerve disorder Grade 2 Glossopharyngeal nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Grade 2 Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C144697 Symptomatic; dietary modification or oral agent indicated Symptomatic; dietary modification or oral agent indicated Grade 2 Glucose Intolerance, CTCAE Grade 2 Glucose intolerance 10052426 C144697 Grade 2 Glucose intolerance Grade 2 Glucose intolerance Symptomatic; dietary modification or oral agent indicated NCI Symptomatic; dietary modification or oral agent indicated CTCAE_v5 Grade 2 Glucose Intolerance, CTCAE PT NCI Grade 2 Glucose intolerance PT CTCAE_v5 ctcae5:C144698 >= +2 SD (standard deviation) above mid parental height or target height >= +2 SD (standard deviation) above mid parental height or target height Grade 2 Growth Accelerated, CTCAE Grade 2 Growth accelerated 10018746 C144698 Grade 2 Growth accelerated Grade 2 Growth accelerated >= +2 SD (standard deviation) above mid parental height or target height NCI >= +2 SD (standard deviation) above mid parental height or target height CTCAE_v5 Grade 2 Growth Accelerated, CTCAE PT NCI Grade 2 Growth accelerated PT CTCAE_v5 ctcae5:C144699 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Growth Hormone Abnormal, CTCAE Grade 2 Growth hormone abnormal 10018748 C144699 Grade 2 Growth hormone abnormal Grade 2 Growth hormone abnormal Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Growth Hormone Abnormal, CTCAE PT NCI Grade 2 Growth hormone abnormal PT CTCAE_v5 ctcae5:C144700 Reduction in growth velocity by 30-49% ideally measured over the period of a year or 0-49% reduction in growth from the baseline growth curve Reduction in growth velocity by 30-49% ideally measured over the period of a year or 0-49% reduction in growth from the baseline growth curve Grade 2 Growth Suppression, CTCAE Grade 2 Growth suppression 10018761 C144700 Grade 2 Growth suppression Grade 2 Growth suppression Reduction in growth velocity by 30-49% ideally measured over the period of a year or 0-49% reduction in growth from the baseline growth curve NCI Reduction in growth velocity by 30-49% ideally measured over the period of a year or 0-49% reduction in growth from the baseline growth curve CTCAE_v5 Grade 2 Growth Suppression, CTCAE PT NCI Grade 2 Growth suppression PT CTCAE_v5 ctcae5:C144701 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Guillain-Barre Syndrome, CTCAE Grade 2 Guillain-Barre syndrome 10018767 C144701 Grade 2 Guillain-Barre syndrome Grade 2 Guillain-Barre syndrome Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Guillain-Barre Syndrome, CTCAE PT NCI Grade 2 Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C144702 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Gum Infection, CTCAE Grade 2 Gum infection 10018784 C144702 Grade 2 Gum infection Grade 2 Gum infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Gum Infection, CTCAE PT NCI Grade 2 Gum infection PT CTCAE_v5 ctcae5:C144703 Moderate hallucinations Moderate hallucinations Grade 2 Hallucinations Grade 2 Hallucinations, CTCAE 10019077 C144703 Grade 2 Hallucinations Grade 2 Hallucinations Moderate hallucinations NCI Moderate hallucinations CTCAE_v5 Grade 2 Hallucinations PT CTCAE_v5 Grade 2 Hallucinations, CTCAE PT NCI ctcae5:C144704 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Headache Grade 2 Headache, CTCAE 10019211 C144704 Grade 2 Headache Grade 2 Headache Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Headache PT CTCAE_v5 Grade 2 Headache, CTCAE PT NCI ctcae5:C144705 Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention not indicated; limiting instrumental ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB at 4 kHz in at least one ear Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention not indicated; limiting instrumental ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB at 4 kHz in at least one ear Grade 2 Hearing Impaired, CTCAE Grade 2 Hearing impaired 10019245 C144705 Grade 2 Hearing impaired Grade 2 Hearing impaired Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention not indicated; limiting instrumental ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB at 4 kHz in at least one ear NCI Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 2 contiguous test frequencies in at least one ear; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention not indicated; limiting instrumental ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift >20 dB at 4 kHz in at least one ear CTCAE_v5 Grade 2 Hearing Impaired, CTCAE PT NCI Grade 2 Hearing impaired PT CTCAE_v5 ctcae5:C144706 Symptoms with moderate activity or exertion Symptoms with moderate activity or exertion Grade 2 Heart Failure, CTCAE Grade 2 Heart failure 10019279 C144706 Grade 2 Heart failure Grade 2 Heart failure Symptoms with moderate activity or exertion NCI Symptoms with moderate activity or exertion CTCAE_v5 Grade 2 Heart Failure, CTCAE PT NCI Grade 2 Heart failure PT CTCAE_v5 ctcae5:C144707 Moderate bleeding; medical intervention indicated Moderate bleeding; medical intervention indicated Grade 2 Hematosalpinx Grade 2 Hematosalpinx, CTCAE 10060602 C144707 Grade 2 Hematosalpinx Grade 2 Hematosalpinx Moderate bleeding; medical intervention indicated NCI Moderate bleeding; medical intervention indicated CTCAE_v5 Grade 2 Hematosalpinx PT CTCAE_v5 Grade 2 Hematosalpinx, CTCAE PT NCI ctcae5:C144708 Symptomatic; urinary catheter or bladder irrigation indicated; limiting instrumental ADL Symptomatic; urinary catheter or bladder irrigation indicated; limiting instrumental ADL Grade 2 Hematuria Grade 2 Hematuria, CTCAE 10019450 C144708 Grade 2 Hematuria Grade 2 Hematuria Symptomatic; urinary catheter or bladder irrigation indicated; limiting instrumental ADL NCI Symptomatic; urinary catheter or bladder irrigation indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Hematuria PT CTCAE_v5 Grade 2 Hematuria, CTCAE PT NCI ctcae5:C144709 Increase in >2-4 g/dL Increase in >2-4 g/dL Grade 2 Hemoglobin Increased, CTCAE Grade 2 Hemoglobin increased 10055599 C144709 Grade 2 Hemoglobin increased Grade 2 Hemoglobin increased Increase in >2-4 g/dL NCI Increase in >2-4 g/dL CTCAE_v5 Grade 2 Hemoglobin Increased, CTCAE PT NCI Grade 2 Hemoglobin increased PT CTCAE_v5 ctcae5:C144710 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Hemorrhoidal Hemorrhage, CTCAE Grade 2 Hemorrhoidal hemorrhage 10060640 C144710 Grade 2 Hemorrhoidal hemorrhage Grade 2 Hemorrhoidal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Hemorrhoidal Hemorrhage, CTCAE PT NCI Grade 2 Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C144711 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Hepatic Hemorrhage, CTCAE Grade 2 Hepatic hemorrhage 10019678 C144711 Grade 2 Hepatic hemorrhage Grade 2 Hepatic hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Hepatic Hemorrhage, CTCAE PT NCI Grade 2 Hepatic hemorrhage PT CTCAE_v5 ctcae5:C144712 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Hepatic Infection, CTCAE Grade 2 Hepatic infection 10056522 C144712 Grade 2 Hepatic infection Grade 2 Hepatic infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Hepatic Infection, CTCAE PT NCI Grade 2 Hepatic infection PT CTCAE_v5 ctcae5:C144713 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Hepatic Pain, CTCAE Grade 2 Hepatic pain 10019705 C144713 Grade 2 Hepatic pain Grade 2 Hepatic pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Hepatic Pain, CTCAE PT NCI Grade 2 Hepatic pain PT CTCAE_v5 ctcae5:C144714 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Hepatitis B Reactivation, CTCAE Grade 2 Hepatitis B reactivation 10058827 C144714 Grade 2 Hepatitis B reactivation Grade 2 Hepatitis B reactivation Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Hepatitis B Reactivation, CTCAE PT NCI Grade 2 Hepatitis B reactivation PT CTCAE_v5 ctcae5:C144715 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Hepatitis Viral, CTCAE Grade 2 Hepatitis viral 10019799 C144715 Grade 2 Hepatitis viral Grade 2 Hepatitis viral Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Hepatitis Viral, CTCAE PT NCI Grade 2 Hepatitis viral PT CTCAE_v5 ctcae5:C144716 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Hepatobiliary Disorders - Other, Specify, CTCAE Grade 2 Hepatobiliary disorders - Other, specify 10019805 C144716 Grade 2 Hepatobiliary disorders - Other, specify Grade 2 Hepatobiliary disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Grade 2 Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C144717 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Herpes Simplex Reactivation, CTCAE Grade 2 Herpes simplex reactivation 10080137 C144717 Grade 2 Herpes simplex reactivation Grade 2 Herpes simplex reactivation Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Herpes Simplex Reactivation, CTCAE PT NCI Grade 2 Herpes simplex reactivation PT CTCAE_v5 ctcae5:C144718 Moderate symptoms; medical intervention indicated; limiting instrumental ADL Moderate symptoms; medical intervention indicated; limiting instrumental ADL Grade 2 Hiccups Grade 2 Hiccups, CTCAE 10020039 C144718 Grade 2 Hiccups Grade 2 Hiccups Moderate symptoms; medical intervention indicated; limiting instrumental ADL NCI Moderate symptoms; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Hiccups PT CTCAE_v5 Grade 2 Hiccups, CTCAE PT NCI ctcae5:C144719 Hairline fracture; mild pain; limiting instrumental ADL; non-operative intervention indicated Hairline fracture; mild pain; limiting instrumental ADL; non-operative intervention indicated Grade 2 Hip Fracture, CTCAE Grade 2 Hip fracture 10020100 C144719 Grade 2 Hip fracture Grade 2 Hip fracture Hairline fracture; mild pain; limiting instrumental ADL; non-operative intervention indicated NCI Hairline fracture; mild pain; limiting instrumental ADL; non-operative intervention indicated CTCAE_v5 Grade 2 Hip Fracture, CTCAE PT NCI Grade 2 Hip fracture PT CTCAE_v5 ctcae5:C144720 In women, increase in length, thickness or density of hair in a male distribution that requires daily shaving or consistent destructive means of hair removal to camouflage; associated with psychosocial impact In women, increase in length, thickness or density of hair in a male distribution that requires daily shaving or consistent destructive means of hair removal to camouflage; associated with psychosocial impact Grade 2 Hirsutism Grade 2 Hirsutism, CTCAE 10020112 C144720 Grade 2 Hirsutism Grade 2 Hirsutism In women, increase in length, thickness or density of hair in a male distribution that requires daily shaving or consistent destructive means of hair removal to camouflage; associated with psychosocial impact NCI In women, increase in length, thickness or density of hair in a male distribution that requires daily shaving or consistent destructive means of hair removal to camouflage; associated with psychosocial impact CTCAE_v5 Grade 2 Hirsutism PT CTCAE_v5 Grade 2 Hirsutism, CTCAE PT NCI ctcae5:C144721 Moderate or persistent voice changes; may require occasional repetition but understandable on telephone; medical evaluation indicated Moderate or persistent voice changes; may require occasional repetition but understandable on telephone; medical evaluation indicated Grade 2 Hoarseness Grade 2 Hoarseness, CTCAE 10020201 C144721 Grade 2 Hoarseness Grade 2 Hoarseness Moderate or persistent voice changes; may require occasional repetition but understandable on telephone; medical evaluation indicated NCI Moderate or persistent voice changes; may require occasional repetition but understandable on telephone; medical evaluation indicated CTCAE_v5 Grade 2 Hoarseness PT CTCAE_v5 Grade 2 Hoarseness, CTCAE PT NCI ctcae5:C144722 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Hot Flashes, CTCAE Grade 2 Hot flashes 10020407 C144722 Grade 2 Hot flashes Grade 2 Hot flashes Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Hot Flashes, CTCAE PT NCI Grade 2 Hot flashes PT CTCAE_v5 ctcae5:C144723 Corrected serum calcium of >11.5-12.5 mg/dL; >2.9-3.1 mmol/L; Ionized calcium >1.5-1.6 mmol/L; symptomatic Corrected serum calcium of >11.5-12.5 mg/dL; >2.9-3.1 mmol/L; Ionized calcium >1.5-1.6 mmol/L; symptomatic Grade 2 Hypercalcemia Grade 2 Hypercalcemia, CTCAE 10020587 C144723 Grade 2 Hypercalcemia Grade 2 Hypercalcemia Corrected serum calcium of >11.5-12.5 mg/dL; >2.9-3.1 mmol/L; Ionized calcium >1.5-1.6 mmol/L; symptomatic NCI Corrected serum calcium of >11.5-12.5 mg/dL; >2.9-3.1 mmol/L; Ionized calcium >1.5-1.6 mmol/L; symptomatic CTCAE_v5 Grade 2 Hypercalcemia PT CTCAE_v5 Grade 2 Hypercalcemia, CTCAE PT NCI ctcae5:C144724 Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes Grade 2 Hyperglycemia Grade 2 Hyperglycemia, CTCAE 10020639 C144724 Grade 2 Hyperglycemia Grade 2 Hyperglycemia Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes NCI Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes CTCAE_v5 Grade 2 Hyperglycemia PT CTCAE_v5 Grade 2 Hyperglycemia, CTCAE PT NCI ctcae5:C144725 Involving >1 site; patient seeks medical intervention; associated with psychosocial impact Involving >1 site; patient seeks medical intervention; associated with psychosocial impact Grade 2 Hyperhidrosis Grade 2 Hyperhidrosis, CTCAE 10020642 C144725 Grade 2 Hyperhidrosis Grade 2 Hyperhidrosis Involving >1 site; patient seeks medical intervention; associated with psychosocial impact NCI Involving >1 site; patient seeks medical intervention; associated with psychosocial impact CTCAE_v5 Grade 2 Hyperhidrosis PT CTCAE_v5 Grade 2 Hyperhidrosis, CTCAE PT NCI ctcae5:C144726 >5.5-6.0 mmol/L; intervention initiated >5.5-6.0 mmol/L; intervention initiated Grade 2 Hyperkalemia Grade 2 Hyperkalemia, CTCAE 10020647 C144726 Grade 2 Hyperkalemia Grade 2 Hyperkalemia >5.5-6.0 mmol/L; intervention initiated NCI >5.5-6.0 mmol/L; intervention initiated CTCAE_v5 Grade 2 Hyperkalemia PT CTCAE_v5 Grade 2 Hyperkalemia, CTCAE PT NCI ctcae5:C144727 Requiring pharmaceutical intervention Requiring pharmaceutical intervention Grade 2 Hyperlipidemia Grade 2 Hyperlipidemia, CTCAE 10020667 C144727 Grade 2 Hyperlipidemia Grade 2 Hyperlipidemia Requiring pharmaceutical intervention NCI Requiring pharmaceutical intervention CTCAE_v5 Grade 2 Hyperlipidemia PT CTCAE_v5 Grade 2 Hyperlipidemia, CTCAE PT NCI ctcae5:C144728 >150-155 mmol/L; intervention initiated >150-155 mmol/L; intervention initiated Grade 2 Hypernatremia Grade 2 Hypernatremia, CTCAE 10020680 C144728 Grade 2 Hypernatremia Grade 2 Hypernatremia >150-155 mmol/L; intervention initiated NCI >150-155 mmol/L; intervention initiated CTCAE_v5 Grade 2 Hypernatremia PT CTCAE_v5 Grade 2 Hypernatremia, CTCAE PT NCI ctcae5:C144729 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Hyperparathyroidism Grade 2 Hyperparathyroidism, CTCAE 10020705 C144729 Grade 2 Hyperparathyroidism Grade 2 Hyperparathyroidism Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Hyperparathyroidism PT CTCAE_v5 Grade 2 Hyperparathyroidism, CTCAE PT NCI ctcae5:C144730 Noninvasive intervention indicated Noninvasive intervention indicated Grade 2 Hyperphosphatemia Grade 2 Hyperphosphatemia, CTCAE 10020712 C144730 Grade 2 Hyperphosphatemia Grade 2 Hyperphosphatemia Noninvasive intervention indicated NCI Noninvasive intervention indicated CTCAE_v5 Grade 2 Hyperphosphatemia PT CTCAE_v5 Grade 2 Hyperphosphatemia, CTCAE PT NCI ctcae5:C144731 Moderate increased need for sleep Moderate increased need for sleep Grade 2 Hypersomnia Grade 2 Hypersomnia, CTCAE 10020765 C144731 Grade 2 Hypersomnia Grade 2 Hypersomnia Moderate increased need for sleep NCI Moderate increased need for sleep CTCAE_v5 Grade 2 Hypersomnia PT CTCAE_v5 Grade 2 Hypersomnia, CTCAE PT NCI ctcae5:C144732 Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL Grade 2 Hyperthyroidism Grade 2 Hyperthyroidism, CTCAE 10020850 C144732 Grade 2 Hyperthyroidism Grade 2 Hyperthyroidism Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL NCI Symptomatic; thyroid suppression therapy indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Hyperthyroidism PT CTCAE_v5 Grade 2 Hyperthyroidism, CTCAE PT NCI ctcae5:C144733 Increase in length, thickness or density of hair at least on the usual exposed areas of the body [face (not limited to beard/moustache area) plus/minus arms] that requires frequent shaving or use of destructive means of hair removal to camouflage; associated with psychosocial impact Increase in length, thickness or density of hair at least on the usual exposed areas of the body [face (not limited to beard/moustache area) plus/minus arms] that requires frequent shaving or use of destructive means of hair removal to camouflage; associated with psychosocial impact Grade 2 Hypertrichosis Grade 2 Hypertrichosis, CTCAE 10020864 C144733 Grade 2 Hypertrichosis Grade 2 Hypertrichosis Increase in length, thickness or density of hair at least on the usual exposed areas of the body [face (not limited to beard/moustache area) plus/minus arms] that requires frequent shaving or use of destructive means of hair removal to camouflage; associated with psychosocial impact NCI Increase in length, thickness or density of hair at least on the usual exposed areas of the body [face (not limited to beard/moustache area) plus/minus arms] that requires frequent shaving or use of destructive means of hair removal to camouflage; associated with psychosocial impact CTCAE_v5 Grade 2 Hypertrichosis PT CTCAE_v5 Grade 2 Hypertrichosis, CTCAE PT NCI ctcae5:C144734 >300 mg/dL-500 mg/dL; >3.42 mmol/L-5.7 mmol/L >300 mg/dL-500 mg/dL; >3.42 mmol/L-5.7 mmol/L Grade 2 Hypertriglyceridemia Grade 2 Hypertriglyceridemia, CTCAE 10020870 C144734 Grade 2 Hypertriglyceridemia Grade 2 Hypertriglyceridemia >300 mg/dL-500 mg/dL; >3.42 mmol/L-5.7 mmol/L NCI >300 mg/dL-500 mg/dL; >3.42 mmol/L-5.7 mmol/L CTCAE_v5 Grade 2 Hypertriglyceridemia PT CTCAE_v5 Grade 2 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C144735 <3-2 g/dL; <30-20 g/L <3-2 g/dL; <30-20 g/L Grade 2 Hypoalbuminemia Grade 2 Hypoalbuminemia, CTCAE 10020943 C144735 Grade 2 Hypoalbuminemia Grade 2 Hypoalbuminemia <3-2 g/dL; <30-20 g/L NCI <3-2 g/dL; <30-20 g/L CTCAE_v5 Grade 2 Hypoalbuminemia PT CTCAE_v5 Grade 2 Hypoalbuminemia, CTCAE PT NCI ctcae5:C144736 Corrected serum calcium of <8.0-7.0 mg/dL; <2.0-1.75 mmol/L; Ionized calcium <1.0-0.9 mmol/L; symptomatic Corrected serum calcium of <8.0-7.0 mg/dL; <2.0-1.75 mmol/L; Ionized calcium <1.0-0.9 mmol/L; symptomatic Grade 2 Hypocalcemia Grade 2 Hypocalcemia, CTCAE 10020949 C144736 Grade 2 Hypocalcemia Grade 2 Hypocalcemia Corrected serum calcium of <8.0-7.0 mg/dL; <2.0-1.75 mmol/L; Ionized calcium <1.0-0.9 mmol/L; symptomatic NCI Corrected serum calcium of <8.0-7.0 mg/dL; <2.0-1.75 mmol/L; Ionized calcium <1.0-0.9 mmol/L; symptomatic CTCAE_v5 Grade 2 Hypocalcemia PT CTCAE_v5 Grade 2 Hypocalcemia, CTCAE PT NCI ctcae5:C144737 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Hypoglossal Nerve Disorder, CTCAE Grade 2 Hypoglossal nerve disorder 10061212 C144737 Grade 2 Hypoglossal nerve disorder Grade 2 Hypoglossal nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Hypoglossal Nerve Disorder, CTCAE PT NCI Grade 2 Hypoglossal nerve disorder PT CTCAE_v5 ctcae5:C144738 <55-40 mg/dL; <3.0-2.2 mmol/L <55-40 mg/dL; <3.0-2.2 mmol/L Grade 2 Hypoglycemia Grade 2 Hypoglycemia, CTCAE 10021005 C144738 Grade 2 Hypoglycemia Grade 2 Hypoglycemia <55-40 mg/dL; <3.0-2.2 mmol/L NCI <55-40 mg/dL; <3.0-2.2 mmol/L CTCAE_v5 Grade 2 Hypoglycemia PT CTCAE_v5 Grade 2 Hypoglycemia, CTCAE PT NCI ctcae5:C144739 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Hypohidrosis Grade 2 Hypohidrosis, CTCAE 10021013 C144739 Grade 2 Hypohidrosis Grade 2 Hypohidrosis Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Hypohidrosis PT CTCAE_v5 Grade 2 Hypohidrosis, CTCAE PT NCI ctcae5:C144740 Symptomatic with <LLN-3.0 mmol/L; intervention indicated Symptomatic with <LLN-3.0 mmol/L; intervention indicated Grade 2 Hypokalemia Grade 2 Hypokalemia, CTCAE 10021018 C144740 Grade 2 Hypokalemia Grade 2 Hypokalemia Symptomatic with <LLN-3.0 mmol/L; intervention indicated NCI Symptomatic with <LLN-3.0 mmol/L; intervention indicated CTCAE_v5 Grade 2 Hypokalemia PT CTCAE_v5 Grade 2 Hypokalemia, CTCAE PT NCI ctcae5:C144741 <1.2-0.9 mg/dL; <0.5-0.4 mmol/L <1.2-0.9 mg/dL; <0.5-0.4 mmol/L Grade 2 Hypomagnesemia Grade 2 Hypomagnesemia, CTCAE 10021028 C144741 Grade 2 Hypomagnesemia Grade 2 Hypomagnesemia <1.2-0.9 mg/dL; <0.5-0.4 mmol/L NCI <1.2-0.9 mg/dL; <0.5-0.4 mmol/L CTCAE_v5 Grade 2 Hypomagnesemia PT CTCAE_v5 Grade 2 Hypomagnesemia, CTCAE PT NCI ctcae5:C144742 125-129 mmol/L and asymptomatic 125-129 mmol/L and asymptomatic Grade 2 Hyponatremia Grade 2 Hyponatremia, CTCAE 10021038 C144742 Grade 2 Hyponatremia Grade 2 Hyponatremia 125-129 mmol/L and asymptomatic NCI 125-129 mmol/L and asymptomatic CTCAE_v5 Grade 2 Hyponatremia PT CTCAE_v5 Grade 2 Hyponatremia, CTCAE PT NCI ctcae5:C144743 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Hypoparathyroidism Grade 2 Hypoparathyroidism, CTCAE 10021041 C144743 Grade 2 Hypoparathyroidism Grade 2 Hypoparathyroidism Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Hypoparathyroidism PT CTCAE_v5 Grade 2 Hypoparathyroidism, CTCAE PT NCI ctcae5:C144744 Oral replacement therapy indicated Oral replacement therapy indicated Grade 2 Hypophosphatemia Grade 2 Hypophosphatemia, CTCAE 10021059 C144744 Grade 2 Hypophosphatemia Grade 2 Hypophosphatemia Oral replacement therapy indicated NCI Oral replacement therapy indicated CTCAE_v5 Grade 2 Hypophosphatemia PT CTCAE_v5 Grade 2 Hypophosphatemia, CTCAE PT NCI ctcae5:C144745 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Hypophysitis Grade 2 Hypophysitis, CTCAE 10062767 C144745 Grade 2 Hypophysitis Grade 2 Hypophysitis Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Hypophysitis PT CTCAE_v5 Grade 2 Hypophysitis, CTCAE PT NCI ctcae5:C144746 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Hypopituitarism Grade 2 Hypopituitarism, CTCAE 10021067 C144746 Grade 2 Hypopituitarism Grade 2 Hypopituitarism Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Hypopituitarism PT CTCAE_v5 Grade 2 Hypopituitarism, CTCAE PT NCI ctcae5:C144747 Symptomatic; thyroid replacement indicated; limiting instrumental ADL Symptomatic; thyroid replacement indicated; limiting instrumental ADL Grade 2 Hypothyroidism Grade 2 Hypothyroidism, CTCAE 10021114 C144747 Grade 2 Hypothyroidism Grade 2 Hypothyroidism Symptomatic; thyroid replacement indicated; limiting instrumental ADL NCI Symptomatic; thyroid replacement indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Hypothyroidism PT CTCAE_v5 Grade 2 Hypothyroidism, CTCAE PT NCI ctcae5:C144751 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Ileal Perforation, CTCAE Grade 2 Ileal perforation 10021305 C144751 Grade 2 Ileal perforation Grade 2 Ileal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Ileal Perforation, CTCAE PT NCI Grade 2 Ileal perforation PT CTCAE_v5 ctcae5:C144752 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Ileal Stenosis, CTCAE Grade 2 Ileal stenosis 10021307 C144752 Grade 2 Ileal stenosis Grade 2 Ileal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Ileal Stenosis, CTCAE PT NCI Grade 2 Ileal stenosis PT CTCAE_v5 ctcae5:C144755 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Immune System Disorders - Other, Specify, CTCAE Grade 2 Immune system disorders - Other, specify 10021428 C144755 Grade 2 Immune system disorders - Other, specify Grade 2 Immune system disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Immune System Disorders - Other, Specify, CTCAE PT NCI Grade 2 Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C144756 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Infections and Infestations - Other, Specify, CTCAE Grade 2 Infections and infestations - Other, specify 10021881 C144756 Grade 2 Infections and infestations - Other, specify Grade 2 Infections and infestations - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Infections and Infestations - Other, Specify, CTCAE PT NCI Grade 2 Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C144757 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Infective Myositis, CTCAE Grade 2 Infective myositis 10021918 C144757 Grade 2 Infective myositis Grade 2 Infective myositis Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Infective Myositis, CTCAE PT NCI Grade 2 Infective myositis PT CTCAE_v5 ctcae5:C144758 Therapy or infusion interruption indicated but responds promptly to symptomatic treatment (e.g., antihistamines, NSAIDS, narcotics, IV fluids); prophylactic medications indicated for <=24 hrs Therapy or infusion interruption indicated but responds promptly to symptomatic treatment (e.g., antihistamines, NSAIDS, narcotics, IV fluids); prophylactic medications indicated for <=24 hrs Grade 2 Infusion Related Reaction, CTCAE Grade 2 Infusion related reaction 10051792 C144758 Grade 2 Infusion related reaction Grade 2 Infusion related reaction Therapy or infusion interruption indicated but responds promptly to symptomatic treatment (e.g., antihistamines, NSAIDS, narcotics, IV fluids); prophylactic medications indicated for <=24 hrs NCI Therapy or infusion interruption indicated but responds promptly to symptomatic treatment (e.g., antihistamines, NSAIDS, narcotics, IV fluids); prophylactic medications indicated for <=24 hrs CTCAE_v5 Grade 2 Infusion Related Reaction, CTCAE PT NCI Grade 2 Infusion related reaction PT CTCAE_v5 ctcae5:C144759 Erythema with associated symptoms (e.g., edema, pain, induration, phlebitis) Erythema with associated symptoms (e.g., edema, pain, induration, phlebitis) Grade 2 Infusion Site Extravasation, CTCAE Grade 2 Infusion site extravasation 10064774 C144759 Grade 2 Infusion site extravasation Grade 2 Infusion site extravasation Erythema with associated symptoms (e.g., edema, pain, induration, phlebitis) NCI Erythema with associated symptoms (e.g., edema, pain, induration, phlebitis) CTCAE_v5 Grade 2 Infusion Site Extravasation, CTCAE PT NCI Grade 2 Infusion site extravasation PT CTCAE_v5 ctcae5:C144760 Pain; lipodystrophy; edema; phlebitis Pain; lipodystrophy; edema; phlebitis Grade 2 Injection Site Reaction, CTCAE Grade 2 Injection site reaction 10022095 C144760 Grade 2 Injection site reaction Grade 2 Injection site reaction Pain; lipodystrophy; edema; phlebitis NCI Pain; lipodystrophy; edema; phlebitis CTCAE_v5 Grade 2 Injection Site Reaction, CTCAE PT NCI Grade 2 Injection site reaction PT CTCAE_v5 ctcae5:C144761 Repair or revision not indicated Repair or revision not indicated Grade 2 Injury To Carotid Artery, CTCAE Grade 2 Injury to carotid artery 10022161 C144761 Grade 2 Injury to carotid artery Grade 2 Injury to carotid artery Repair or revision not indicated NCI Repair or revision not indicated CTCAE_v5 Grade 2 Injury To Carotid Artery, CTCAE PT NCI Grade 2 Injury to carotid artery PT CTCAE_v5 ctcae5:C144763 Repair or revision not indicated Repair or revision not indicated Grade 2 Injury To Jugular Vein, CTCAE Grade 2 Injury to jugular vein 10065849 C144763 Grade 2 Injury to jugular vein Grade 2 Injury to jugular vein Repair or revision not indicated NCI Repair or revision not indicated CTCAE_v5 Grade 2 Injury To Jugular Vein, CTCAE PT NCI Grade 2 Injury to jugular vein PT CTCAE_v5 ctcae5:C144764 Symptomatic; repair or revision not indicated Symptomatic; repair or revision not indicated Grade 2 Injury To Superior Vena Cava, CTCAE Grade 2 Injury to superior vena cava 10022356 C144764 Grade 2 Injury to superior vena cava Grade 2 Injury to superior vena cava Symptomatic; repair or revision not indicated NCI Symptomatic; repair or revision not indicated CTCAE_v5 Grade 2 Injury To Superior Vena Cava, CTCAE PT NCI Grade 2 Injury to superior vena cava PT CTCAE_v5 ctcae5:C144765 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Grade 2 Injury, poisoning and procedural complications - Other, specify 10022117 C144765 Grade 2 Injury, poisoning and procedural complications - Other, specify Grade 2 Injury, poisoning and procedural complications - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Grade 2 Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C144766 >1.5-2.5; >1.5-2.5 x baseline if on anticoagulation; dose adjustment indicated >1.5-2.5; >1.5-2.5 x baseline if on anticoagulation; dose adjustment indicated Grade 2 INR Increased, CTCAE Grade 2 INR increased 10022402 C144766 Grade 2 INR increased Grade 2 INR increased >1.5-2.5; >1.5-2.5 x baseline if on anticoagulation; dose adjustment indicated NCI >1.5-2.5; >1.5-2.5 x baseline if on anticoagulation; dose adjustment indicated CTCAE_v5 Grade 2 INR Increased, CTCAE PT NCI Grade 2 INR increased PT CTCAE_v5 ctcae5:C144767 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Intestinal Stoma Leak, CTCAE Grade 2 Intestinal stoma leak 10059095 C144767 Grade 2 Intestinal stoma leak Grade 2 Intestinal stoma leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Intestinal Stoma Leak, CTCAE PT NCI Grade 2 Intestinal stoma leak PT CTCAE_v5 ctcae5:C144768 Self-limited; intervention not indicated Self-limited; intervention not indicated Grade 2 Intestinal Stoma Obstruction, CTCAE Grade 2 Intestinal stoma obstruction 10059094 C144768 Grade 2 Intestinal stoma obstruction Grade 2 Intestinal stoma obstruction Self-limited; intervention not indicated NCI Self-limited; intervention not indicated CTCAE_v5 Grade 2 Intestinal Stoma Obstruction, CTCAE PT NCI Grade 2 Intestinal stoma obstruction PT CTCAE_v5 ctcae5:C144769 Moderate bleeding; medical intervention indicated Moderate bleeding; medical intervention indicated Grade 2 Intestinal Stoma Site Bleeding, CTCAE Grade 2 Intestinal stoma site bleeding 10049468 C144769 Grade 2 Intestinal stoma site bleeding Grade 2 Intestinal stoma site bleeding Moderate bleeding; medical intervention indicated NCI Moderate bleeding; medical intervention indicated CTCAE_v5 Grade 2 Intestinal Stoma Site Bleeding, CTCAE PT NCI Grade 2 Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C144770 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Intra-Abdominal Hemorrhage, CTCAE Grade 2 Intra-abdominal hemorrhage 10055291 C144770 Grade 2 Intra-abdominal hemorrhage Grade 2 Intra-abdominal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Intra-Abdominal Hemorrhage, CTCAE PT NCI Grade 2 Intra-abdominal hemorrhage PT CTCAE_v5 ctcae5:C144771 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Intracranial Hemorrhage, CTCAE Grade 2 Intracranial hemorrhage 10022763 C144771 Grade 2 Intracranial hemorrhage Grade 2 Intracranial hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Intracranial Hemorrhage, CTCAE PT NCI Grade 2 Intracranial hemorrhage PT CTCAE_v5 ctcae5:C144772 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Arterial Injury, CTCAE Grade 2 Intraoperative arterial injury 10065826 C144772 Grade 2 Intraoperative arterial injury Grade 2 Intraoperative arterial injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Arterial Injury, CTCAE PT NCI Grade 2 Intraoperative arterial injury PT CTCAE_v5 ctcae5:C144773 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Breast Injury, CTCAE Grade 2 Intraoperative breast injury 10065831 C144773 Grade 2 Intraoperative breast injury Grade 2 Intraoperative breast injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Breast Injury, CTCAE PT NCI Grade 2 Intraoperative breast injury PT CTCAE_v5 ctcae5:C144774 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Ear Injury, CTCAE Grade 2 Intraoperative ear injury 10065844 C144774 Grade 2 Intraoperative ear injury Grade 2 Intraoperative ear injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Ear Injury, CTCAE PT NCI Grade 2 Intraoperative ear injury PT CTCAE_v5 ctcae5:C144775 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Endocrine Injury, CTCAE Grade 2 Intraoperative endocrine injury 10065834 C144775 Grade 2 Intraoperative endocrine injury Grade 2 Intraoperative endocrine injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Endocrine Injury, CTCAE PT NCI Grade 2 Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C144776 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Gastrointestinal Injury, CTCAE Grade 2 Intraoperative gastrointestinal injury 10065825 C144776 Grade 2 Intraoperative gastrointestinal injury Grade 2 Intraoperative gastrointestinal injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Grade 2 Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C144777 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Head and Neck Injury, CTCAE Grade 2 Intraoperative head and neck injury 10065842 C144777 Grade 2 Intraoperative head and neck injury Grade 2 Intraoperative head and neck injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Head and Neck Injury, CTCAE PT NCI Grade 2 Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C144778 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Hepatobiliary Injury, CTCAE Grade 2 Intraoperative hepatobiliary injury 10065827 C144778 Grade 2 Intraoperative hepatobiliary injury Grade 2 Intraoperative hepatobiliary injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Grade 2 Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C144779 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Musculoskeletal Injury, CTCAE Grade 2 Intraoperative musculoskeletal injury 10065829 C144779 Grade 2 Intraoperative musculoskeletal injury Grade 2 Intraoperative musculoskeletal injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Grade 2 Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C144780 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Neurological Injury, CTCAE Grade 2 Intraoperative neurological injury 10065830 C144780 Grade 2 Intraoperative neurological injury Grade 2 Intraoperative neurological injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Neurological Injury, CTCAE PT NCI Grade 2 Intraoperative neurological injury PT CTCAE_v5 ctcae5:C144781 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Ocular Injury, CTCAE Grade 2 Intraoperative ocular injury 10065841 C144781 Grade 2 Intraoperative ocular injury Grade 2 Intraoperative ocular injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Ocular Injury, CTCAE PT NCI Grade 2 Intraoperative ocular injury PT CTCAE_v5 ctcae5:C144782 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Renal Injury, CTCAE Grade 2 Intraoperative renal injury 10065845 C144782 Grade 2 Intraoperative renal injury Grade 2 Intraoperative renal injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Renal Injury, CTCAE PT NCI Grade 2 Intraoperative renal injury PT CTCAE_v5 ctcae5:C144783 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Reproductive Tract Injury, CTCAE Grade 2 Intraoperative reproductive tract injury 10065840 C144783 Grade 2 Intraoperative reproductive tract injury Grade 2 Intraoperative reproductive tract injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Grade 2 Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C144784 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Respiratory Injury, CTCAE Grade 2 Intraoperative respiratory injury 10065832 C144784 Grade 2 Intraoperative respiratory injury Grade 2 Intraoperative respiratory injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Respiratory Injury, CTCAE PT NCI Grade 2 Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C144785 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 2 Intraoperative Splenic Injury, CTCAE Grade 2 Intraoperative splenic injury 10065847 C144785 Grade 2 Intraoperative splenic injury Grade 2 Intraoperative splenic injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Splenic Injury, CTCAE PT NCI Grade 2 Intraoperative splenic injury PT CTCAE_v5 ctcae5:C144786 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Urinary Injury, CTCAE Grade 2 Intraoperative urinary injury 10065828 C144786 Grade 2 Intraoperative urinary injury Grade 2 Intraoperative urinary injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Urinary Injury, CTCAE PT NCI Grade 2 Intraoperative urinary injury PT CTCAE_v5 ctcae5:C144787 Partial resection of injured organ/structure indicated Partial resection of injured organ/structure indicated Grade 2 Intraoperative Venous Injury, CTCAE Grade 2 Intraoperative venous injury 10065848 C144787 Grade 2 Intraoperative venous injury Grade 2 Intraoperative venous injury Partial resection of injured organ/structure indicated NCI Partial resection of injured organ/structure indicated CTCAE_v5 Grade 2 Intraoperative Venous Injury, CTCAE PT NCI Grade 2 Intraoperative venous injury PT CTCAE_v5 ctcae5:C144788 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Investigations - Other, Specify, CTCAE Grade 2 Investigations - Other, specify 10022891 C144788 Grade 2 Investigations - Other, specify Grade 2 Investigations - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Investigations - Other, Specify, CTCAE PT NCI Grade 2 Investigations - Other, specify PT CTCAE_v5 ctcae5:C144789 Intermittent/irregular menses for more than 3 consecutive menstrual cycles Intermittent/irregular menses for more than 3 consecutive menstrual cycles Grade 2 Irregular Menstruation, CTCAE Grade 2 Irregular menstruation 10022992 C144789 Grade 2 Irregular menstruation Grade 2 Irregular menstruation Intermittent/irregular menses for more than 3 consecutive menstrual cycles NCI Intermittent/irregular menses for more than 3 consecutive menstrual cycles CTCAE_v5 Grade 2 Irregular Menstruation, CTCAE PT NCI Grade 2 Irregular menstruation PT CTCAE_v5 ctcae5:C144790 Moderate; limiting instrumental ADL; increased attention indicated Moderate; limiting instrumental ADL; increased attention indicated Grade 2 Irritability Grade 2 Irritability, CTCAE 10022998 C144790 Grade 2 Irritability Grade 2 Irritability Moderate; limiting instrumental ADL; increased attention indicated NCI Moderate; limiting instrumental ADL; increased attention indicated CTCAE_v5 Grade 2 Irritability PT CTCAE_v5 Grade 2 Irritability, CTCAE PT NCI ctcae5:C144791 Moderate symptoms Moderate symptoms Grade 2 Ischemia Cerebrovascular, CTCAE Grade 2 Ischemia cerebrovascular 10023030 C144791 Grade 2 Ischemia cerebrovascular Grade 2 Ischemia cerebrovascular Moderate symptoms NCI Moderate symptoms CTCAE_v5 Grade 2 Ischemia Cerebrovascular, CTCAE PT NCI Grade 2 Ischemia cerebrovascular PT CTCAE_v5 ctcae5:C144795 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Jejunal Perforation, CTCAE Grade 2 Jejunal perforation 10023174 C144795 Grade 2 Jejunal perforation Grade 2 Jejunal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Jejunal Perforation, CTCAE PT NCI Grade 2 Jejunal perforation PT CTCAE_v5 ctcae5:C144796 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Jejunal Stenosis, CTCAE Grade 2 Jejunal stenosis 10023176 C144796 Grade 2 Jejunal stenosis Grade 2 Jejunal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Jejunal Stenosis, CTCAE PT NCI Grade 2 Jejunal stenosis PT CTCAE_v5 ctcae5:C144798 Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral); needle aspiration indicated (single or multiple) Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral); needle aspiration indicated (single or multiple) Grade 2 Joint Infection, CTCAE Grade 2 Joint infection 10023216 C144798 Grade 2 Joint infection Grade 2 Joint infection Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral); needle aspiration indicated (single or multiple) NCI Localized; local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral); needle aspiration indicated (single or multiple) CTCAE_v5 Grade 2 Joint Infection, CTCAE PT NCI Grade 2 Joint infection PT CTCAE_v5 ctcae5:C144799 Rotation <60 degrees to right or left; <60 degrees of flexion Rotation <60 degrees to right or left; <60 degrees of flexion Grade 2 Joint Range of Motion Decreased Cervical Spine, CTCAE Grade 2 Joint range of motion decreased cervical spine 10065796 C144799 Grade 2 Joint range of motion decreased cervical spine Grade 2 Joint range of motion decreased cervical spine Rotation <60 degrees to right or left; <60 degrees of flexion NCI Rotation <60 degrees to right or left; <60 degrees of flexion CTCAE_v5 Grade 2 Joint Range of Motion Decreased Cervical Spine, CTCAE PT NCI Grade 2 Joint range of motion decreased cervical spine PT CTCAE_v5 ctcae5:C144800 Pain with range of motion (ROM) in lumbar spine; requires a reaching aid to pick up a very light object from the floor Pain with range of motion (ROM) in lumbar spine; requires a reaching aid to pick up a very light object from the floor Grade 2 Joint Range of Motion Decreased Lumbar Spine, CTCAE Grade 2 Joint range of motion decreased lumbar spine 10065800 C144800 Grade 2 Joint range of motion decreased lumbar spine Grade 2 Joint range of motion decreased lumbar spine Pain with range of motion (ROM) in lumbar spine; requires a reaching aid to pick up a very light object from the floor NCI Pain with range of motion (ROM) in lumbar spine; requires a reaching aid to pick up a very light object from the floor CTCAE_v5 Grade 2 Joint Range of Motion Decreased Lumbar Spine, CTCAE PT NCI Grade 2 Joint range of motion decreased lumbar spine PT CTCAE_v5 ctcae5:C144801 >25-50% decrease in ROM; limiting instrumental ADL >25-50% decrease in ROM; limiting instrumental ADL Grade 2 Joint Range of Motion Decreased, CTCAE Grade 2 Joint range of motion decreased 10048706 C144801 Grade 2 Joint range of motion decreased Grade 2 Joint range of motion decreased >25-50% decrease in ROM; limiting instrumental ADL NCI >25-50% decrease in ROM; limiting instrumental ADL CTCAE_v5 Grade 2 Joint Range of Motion Decreased, CTCAE PT NCI Grade 2 Joint range of motion decreased PT CTCAE_v5 ctcae5:C144802 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Kidney Anastomotic Leak, CTCAE Grade 2 Kidney anastomotic leak 10065803 C144802 Grade 2 Kidney anastomotic leak Grade 2 Kidney anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Kidney Anastomotic Leak, CTCAE PT NCI Grade 2 Kidney anastomotic leak PT CTCAE_v5 ctcae5:C144803 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Kidney Infection, CTCAE Grade 2 Kidney infection 10023424 C144803 Grade 2 Kidney infection Grade 2 Kidney infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Kidney Infection, CTCAE PT NCI Grade 2 Kidney infection PT CTCAE_v5 ctcae5:C144804 Moderate accentuation; limiting instrumental ADL Moderate accentuation; limiting instrumental ADL Grade 2 Kyphosis Grade 2 Kyphosis, CTCAE 10023509 C144804 Grade 2 Kyphosis Grade 2 Kyphosis Moderate accentuation; limiting instrumental ADL NCI Moderate accentuation; limiting instrumental ADL CTCAE_v5 Grade 2 Kyphosis PT CTCAE_v5 Grade 2 Kyphosis, CTCAE PT NCI ctcae5:C144805 Changes in lactation, significantly affecting breast production or expression of breast milk Changes in lactation, significantly affecting breast production or expression of breast milk Grade 2 Lactation Disorder, CTCAE Grade 2 Lactation disorder 10061261 C144805 Grade 2 Lactation disorder Grade 2 Lactation disorder Changes in lactation, significantly affecting breast production or expression of breast milk NCI Changes in lactation, significantly affecting breast production or expression of breast milk CTCAE_v5 Grade 2 Lactation Disorder, CTCAE PT NCI Grade 2 Lactation disorder PT CTCAE_v5 ctcae5:C144806 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Large Intestinal Anastomotic Leak, CTCAE Grade 2 Large intestinal anastomotic leak 10065891 C144806 Grade 2 Large intestinal anastomotic leak Grade 2 Large intestinal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Large Intestinal Anastomotic Leak, CTCAE PT NCI Grade 2 Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C144807 Symptomatic; medical intervention indicated (e.g., dexamethasone, epinephrine, antihistamines) Symptomatic; medical intervention indicated (e.g., dexamethasone, epinephrine, antihistamines) Grade 2 Laryngeal Edema, CTCAE Grade 2 Laryngeal edema 10023838 C144807 Grade 2 Laryngeal edema Grade 2 Laryngeal edema Symptomatic; medical intervention indicated (e.g., dexamethasone, epinephrine, antihistamines) NCI Symptomatic; medical intervention indicated (e.g., dexamethasone, epinephrine, antihistamines) CTCAE_v5 Grade 2 Laryngeal Edema, CTCAE PT NCI Grade 2 Laryngeal edema PT CTCAE_v5 ctcae5:C144810 Moderate sore throat; analgesics indicated Moderate sore throat; analgesics indicated Grade 2 Laryngeal Inflammation, CTCAE Grade 2 Laryngeal inflammation 10065735 C144810 Grade 2 Laryngeal inflammation Grade 2 Laryngeal inflammation Moderate sore throat; analgesics indicated NCI Moderate sore throat; analgesics indicated CTCAE_v5 Grade 2 Laryngeal Inflammation, CTCAE PT NCI Grade 2 Laryngeal inflammation PT CTCAE_v5 ctcae5:C144811 Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL Grade 2 Laryngeal Mucositis, CTCAE Grade 2 Laryngeal mucositis 10065880 C144811 Grade 2 Laryngeal mucositis Grade 2 Laryngeal mucositis Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL NCI Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL CTCAE_v5 Grade 2 Laryngeal Mucositis, CTCAE PT NCI Grade 2 Laryngeal mucositis PT CTCAE_v5 ctcae5:C144812 Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Grade 2 Laryngeal Obstruction, CTCAE Grade 2 Laryngeal obstruction 10059639 C144812 Grade 2 Laryngeal obstruction Grade 2 Laryngeal obstruction Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL NCI Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL CTCAE_v5 Grade 2 Laryngeal Obstruction, CTCAE PT NCI Grade 2 Laryngeal obstruction PT CTCAE_v5 ctcae5:C144813 Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Grade 2 Laryngeal Stenosis, CTCAE Grade 2 Laryngeal stenosis 10023862 C144813 Grade 2 Laryngeal stenosis Grade 2 Laryngeal stenosis Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL NCI Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL CTCAE_v5 Grade 2 Laryngeal Stenosis, CTCAE PT NCI Grade 2 Laryngeal stenosis PT CTCAE_v5 ctcae5:C144814 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Laryngitis Grade 2 Laryngitis, CTCAE 10023874 C144814 Grade 2 Laryngitis Grade 2 Laryngitis Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Laryngitis PT CTCAE_v5 Grade 2 Laryngitis, CTCAE PT NCI ctcae5:C144815 Moderate symptoms; mild anxiety, but no dyspnea; short duration of observation and/or anxiolytic indicated; limiting instrumental ADL Moderate symptoms; mild anxiety, but no dyspnea; short duration of observation and/or anxiolytic indicated; limiting instrumental ADL Grade 2 Laryngopharyngeal Dysesthesia, CTCAE Grade 2 Laryngopharyngeal dysesthesia 10062667 C144815 Grade 2 Laryngopharyngeal dysesthesia Grade 2 Laryngopharyngeal dysesthesia Moderate symptoms; mild anxiety, but no dyspnea; short duration of observation and/or anxiolytic indicated; limiting instrumental ADL NCI Moderate symptoms; mild anxiety, but no dyspnea; short duration of observation and/or anxiolytic indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Grade 2 Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C144816 Transient episode; intervention not indicated Transient episode; intervention not indicated Grade 2 Laryngospasm Grade 2 Laryngospasm, CTCAE 10023891 C144816 Grade 2 Laryngospasm Grade 2 Laryngospasm Transient episode; intervention not indicated NCI Transient episode; intervention not indicated CTCAE_v5 Grade 2 Laryngospasm PT CTCAE_v5 Grade 2 Laryngospasm, CTCAE PT NCI ctcae5:C144817 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Lethargy Grade 2 Lethargy, CTCAE 10024264 C144817 Grade 2 Lethargy Grade 2 Lethargy Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Lethargy PT CTCAE_v5 Grade 2 Lethargy, CTCAE PT NCI ctcae5:C144818 Moderate symptoms; focal T2/FLAIR hyperintensities, involving periventricular white matter extending into centrum semiovale or involving 1/3 to 2/3 of susceptible areas of cerebrum +/- moderate increase in SAS and/or moderate ventriculomegaly Moderate symptoms; focal T2/FLAIR hyperintensities, involving periventricular white matter extending into centrum semiovale or involving 1/3 to 2/3 of susceptible areas of cerebrum +/- moderate increase in SAS and/or moderate ventriculomegaly Grade 2 Leukoencephalopathy Grade 2 Leukoencephalopathy, CTCAE 10024382 C144818 Grade 2 Leukoencephalopathy Grade 2 Leukoencephalopathy Moderate symptoms; focal T2/FLAIR hyperintensities, involving periventricular white matter extending into centrum semiovale or involving 1/3 to 2/3 of susceptible areas of cerebrum +/- moderate increase in SAS and/or moderate ventriculomegaly NCI Moderate symptoms; focal T2/FLAIR hyperintensities, involving periventricular white matter extending into centrum semiovale or involving 1/3 to 2/3 of susceptible areas of cerebrum +/- moderate increase in SAS and/or moderate ventriculomegaly CTCAE_v5 Grade 2 Leukoencephalopathy PT CTCAE_v5 Grade 2 Leukoencephalopathy, CTCAE PT NCI ctcae5:C144819 Decrease in sexual interest adversely affecting relationship Decrease in sexual interest adversely affecting relationship Grade 2 Libido Decreased, CTCAE Grade 2 Libido decreased 10024419 C144819 Grade 2 Libido decreased Grade 2 Libido decreased Decrease in sexual interest adversely affecting relationship NCI Decrease in sexual interest adversely affecting relationship CTCAE_v5 Grade 2 Libido Decreased, CTCAE PT NCI Grade 2 Libido decreased PT CTCAE_v5 ctcae5:C144820 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Lip Infection, CTCAE Grade 2 Lip infection 10065755 C144820 Grade 2 Lip infection Grade 2 Lip infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Lip Infection, CTCAE PT NCI Grade 2 Lip infection PT CTCAE_v5 ctcae5:C144821 >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic Grade 2 Lipase Increased, CTCAE Grade 2 Lipase increased 10024574 C144821 Grade 2 Lipase increased Grade 2 Lipase increased >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic NCI >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic CTCAE_v5 Grade 2 Lipase Increased, CTCAE PT NCI Grade 2 Lipase increased PT CTCAE_v5 ctcae5:C144822 Covering 10-30% BSA and associated tenderness; limiting instrumental ADL Covering 10-30% BSA and associated tenderness; limiting instrumental ADL Grade 2 Lipohypertrophy Grade 2 Lipohypertrophy, CTCAE 10062315 C144822 Grade 2 Lipohypertrophy Grade 2 Lipohypertrophy Covering 10-30% BSA and associated tenderness; limiting instrumental ADL NCI Covering 10-30% BSA and associated tenderness; limiting instrumental ADL CTCAE_v5 Grade 2 Lipohypertrophy PT CTCAE_v5 Grade 2 Lipohypertrophy, CTCAE PT NCI ctcae5:C144823 Moderate localized edema and intervention indicated; limiting instrumental ADL Moderate localized edema and intervention indicated; limiting instrumental ADL Grade 2 Localized Edema, CTCAE Grade 2 Localized edema 10062466 C144823 Grade 2 Localized edema Grade 2 Localized edema Moderate localized edema and intervention indicated; limiting instrumental ADL NCI Moderate localized edema and intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Localized Edema, CTCAE PT NCI Grade 2 Localized edema PT CTCAE_v5 ctcae5:C144824 Moderate accentuation; limiting instrumental ADL Moderate accentuation; limiting instrumental ADL Grade 2 Lordosis Grade 2 Lordosis, CTCAE 10024842 C144824 Grade 2 Lordosis Grade 2 Lordosis Moderate accentuation; limiting instrumental ADL NCI Moderate accentuation; limiting instrumental ADL CTCAE_v5 Grade 2 Lordosis PT CTCAE_v5 Grade 2 Lordosis, CTCAE PT NCI ctcae5:C144825 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Lower Gastrointestinal Hemorrhage, CTCAE Grade 2 Lower gastrointestinal hemorrhage 10051746 C144825 Grade 2 Lower gastrointestinal hemorrhage Grade 2 Lower gastrointestinal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 2 Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C144826 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Lung Infection, CTCAE Grade 2 Lung infection 10061229 C144826 Grade 2 Lung infection Grade 2 Lung infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Lung Infection, CTCAE PT NCI Grade 2 Lung infection PT CTCAE_v5 ctcae5:C144827 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Lymph Gland Infection, CTCAE Grade 2 Lymph gland infection 10050823 C144827 Grade 2 Lymph gland infection Grade 2 Lymph gland infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Lymph Gland Infection, CTCAE PT NCI Grade 2 Lymph gland infection PT CTCAE_v5 ctcae5:C144828 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Lymph Leakage, CTCAE Grade 2 Lymph leakage 10065773 C144828 Grade 2 Lymph leakage Grade 2 Lymph leakage Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Lymph Leakage, CTCAE PT NCI Grade 2 Lymph leakage PT CTCAE_v5 ctcae5:C144829 Marked discoloration; leathery skin texture; papillary formation; limiting instrumental ADL Marked discoloration; leathery skin texture; papillary formation; limiting instrumental ADL Grade 2 Lymphedema Grade 2 Lymphedema, CTCAE 10025233 C144829 Grade 2 Lymphedema Grade 2 Lymphedema Marked discoloration; leathery skin texture; papillary formation; limiting instrumental ADL NCI Marked discoloration; leathery skin texture; papillary formation; limiting instrumental ADL CTCAE_v5 Grade 2 Lymphedema PT CTCAE_v5 Grade 2 Lymphedema, CTCAE PT NCI ctcae5:C144830 <800-500/mm3; <0.8-0.5 x 10e9/L <800-500/mm3; <0.8-0.5 x 10e9/L Grade 2 Lymphocyte Count Decreased, CTCAE Grade 2 Lymphocyte count decreased 10025256 C144830 Grade 2 Lymphocyte count decreased Grade 2 Lymphocyte count decreased <800-500/mm3; <0.8-0.5 x 10e9/L NCI <800-500/mm3; <0.8-0.5 x 10e9/L CTCAE_v5 Grade 2 Lymphocyte Count Decreased, CTCAE PT NCI Grade 2 Lymphocyte count decreased PT CTCAE_v5 ctcae5:C144831 >4000/mm3-20,000/mm3 >4000/mm3-20,000/mm3 Grade 2 Lymphocyte Count Increased, CTCAE Grade 2 Lymphocyte count increased 10025258 C144831 Grade 2 Lymphocyte count increased Grade 2 Lymphocyte count increased >4000/mm3-20,000/mm3 NCI >4000/mm3-20,000/mm3 CTCAE_v5 Grade 2 Lymphocyte Count Increased, CTCAE PT NCI Grade 2 Lymphocyte count increased PT CTCAE_v5 ctcae5:C144832 Uneasiness or lack of well being limiting instrumental ADL Uneasiness or lack of well being limiting instrumental ADL Grade 2 Malaise Grade 2 Malaise, CTCAE 10025482 C144832 Grade 2 Malaise Grade 2 Malaise Uneasiness or lack of well being limiting instrumental ADL NCI Uneasiness or lack of well being limiting instrumental ADL CTCAE_v5 Grade 2 Malaise PT CTCAE_v5 Grade 2 Malaise, CTCAE PT NCI ctcae5:C144833 Moderate manic symptoms (e.g., relationship and work difficulties; poor hygiene) Moderate manic symptoms (e.g., relationship and work difficulties; poor hygiene) Grade 2 Mania Grade 2 Mania, CTCAE 10026749 C144833 Grade 2 Mania Grade 2 Mania Moderate manic symptoms (e.g., relationship and work difficulties; poor hygiene) NCI Moderate manic symptoms (e.g., relationship and work difficulties; poor hygiene) CTCAE_v5 Grade 2 Mania PT CTCAE_v5 Grade 2 Mania, CTCAE PT NCI ctcae5:C144835 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Meningismus Grade 2 Meningismus, CTCAE 10027198 C144835 Grade 2 Meningismus Grade 2 Meningismus Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Meningismus PT CTCAE_v5 Grade 2 Meningismus, CTCAE PT NCI ctcae5:C144836 Moderate symptoms; medical intervention indicated (e.g., hormones) Moderate symptoms; medical intervention indicated (e.g., hormones) Grade 2 Menorrhagia Grade 2 Menorrhagia, CTCAE 10027313 C144836 Grade 2 Menorrhagia Grade 2 Menorrhagia Moderate symptoms; medical intervention indicated (e.g., hormones) NCI Moderate symptoms; medical intervention indicated (e.g., hormones) CTCAE_v5 Grade 2 Menorrhagia PT CTCAE_v5 Grade 2 Menorrhagia, CTCAE PT NCI ctcae5:C144837 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Grade 2 Metabolism and nutrition disorders - Other, specify 10027433 C144837 Grade 2 Metabolism and nutrition disorders - Other, specify Grade 2 Metabolism and nutrition disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Grade 2 Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C144838 >ULN >ULN Grade 2 Methemoglobinemia Grade 2 Methemoglobinemia, CTCAE 10027506 C144838 Grade 2 Methemoglobinemia Grade 2 Methemoglobinemia >ULN NCI >ULN CTCAE_v5 Grade 2 Methemoglobinemia PT CTCAE_v5 Grade 2 Methemoglobinemia, CTCAE PT NCI ctcae5:C144839 Serous otitis, medical intervention indicated Serous otitis, medical intervention indicated Grade 2 Middle Ear Inflammation, CTCAE Grade 2 Middle ear inflammation 10065838 C144839 Grade 2 Middle ear inflammation Grade 2 Middle ear inflammation Serous otitis, medical intervention indicated NCI Serous otitis, medical intervention indicated CTCAE_v5 Grade 2 Middle Ear Inflammation, CTCAE PT NCI Grade 2 Middle ear inflammation PT CTCAE_v5 ctcae5:C144840 Asymptomatic; moderate regurgitation or stenosis by imaging Asymptomatic; moderate regurgitation or stenosis by imaging Grade 2 Mitral Valve Disease, CTCAE Grade 2 Mitral valve disease 10061532 C144840 Grade 2 Mitral valve disease Grade 2 Mitral valve disease Asymptomatic; moderate regurgitation or stenosis by imaging NCI Asymptomatic; moderate regurgitation or stenosis by imaging CTCAE_v5 Grade 2 Mitral Valve Disease, CTCAE PT NCI Grade 2 Mitral valve disease PT CTCAE_v5 ctcae5:C144843 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Movements Involuntary, CTCAE Grade 2 Movements involuntary 10028041 C144843 Grade 2 Movements involuntary Grade 2 Movements involuntary Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Movements Involuntary, CTCAE PT NCI Grade 2 Movements involuntary PT CTCAE_v5 ctcae5:C144844 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Mucosal Infection, CTCAE Grade 2 Mucosal infection 10065764 C144844 Grade 2 Mucosal infection Grade 2 Mucosal infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Mucosal Infection, CTCAE PT NCI Grade 2 Mucosal infection PT CTCAE_v5 ctcae5:C144845 Moderate pain or ulcer that does not interfere with oral intake; modified diet indicated Moderate pain or ulcer that does not interfere with oral intake; modified diet indicated Grade 2 Mucositis Oral, CTCAE Grade 2 Mucositis oral 10028130 C144845 Grade 2 Mucositis oral Grade 2 Mucositis oral Moderate pain or ulcer that does not interfere with oral intake; modified diet indicated NCI Moderate pain or ulcer that does not interfere with oral intake; modified diet indicated CTCAE_v5 Grade 2 Mucositis Oral, CTCAE PT NCI Grade 2 Mucositis oral PT CTCAE_v5 ctcae5:C144846 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Muscle Cramp, CTCAE Grade 2 Muscle cramp 10028294 C144846 Grade 2 Muscle cramp Grade 2 Muscle cramp Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Cramp, CTCAE PT NCI Grade 2 Muscle cramp PT CTCAE_v5 ctcae5:C144847 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Muscle Weakness Left-Sided, CTCAE Grade 2 Muscle weakness left-sided 10065780 C144847 Grade 2 Muscle weakness left-sided Grade 2 Muscle weakness left-sided Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Weakness Left-Sided, CTCAE PT NCI Grade 2 Muscle weakness left-sided PT CTCAE_v5 ctcae5:C144848 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Muscle Weakness Lower Limb, CTCAE Grade 2 Muscle weakness lower limb 10065776 C144848 Grade 2 Muscle weakness lower limb Grade 2 Muscle weakness lower limb Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Weakness Lower Limb, CTCAE PT NCI Grade 2 Muscle weakness lower limb PT CTCAE_v5 ctcae5:C144849 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Muscle Weakness Right-Sided, CTCAE Grade 2 Muscle weakness right-sided 10065794 C144849 Grade 2 Muscle weakness right-sided Grade 2 Muscle weakness right-sided Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Weakness Right-Sided, CTCAE PT NCI Grade 2 Muscle weakness right-sided PT CTCAE_v5 ctcae5:C144850 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Muscle Weakness Trunk, CTCAE Grade 2 Muscle weakness trunk 10065795 C144850 Grade 2 Muscle weakness trunk Grade 2 Muscle weakness trunk Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Weakness Trunk, CTCAE PT NCI Grade 2 Muscle weakness trunk PT CTCAE_v5 ctcae5:C144851 Symptomatic; evident on physical exam; limiting instrumental ADL Symptomatic; evident on physical exam; limiting instrumental ADL Grade 2 Muscle Weakness Upper Limb, CTCAE Grade 2 Muscle weakness upper limb 10065895 C144851 Grade 2 Muscle weakness upper limb Grade 2 Muscle weakness upper limb Symptomatic; evident on physical exam; limiting instrumental ADL NCI Symptomatic; evident on physical exam; limiting instrumental ADL CTCAE_v5 Grade 2 Muscle Weakness Upper Limb, CTCAE PT NCI Grade 2 Muscle weakness upper limb PT CTCAE_v5 ctcae5:C144852 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Grade 2 Musculoskeletal and connective tissue disorder - Other, specify 10028395 C144852 Grade 2 Musculoskeletal and connective tissue disorder - Other, specify Grade 2 Musculoskeletal and connective tissue disorder - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Grade 2 Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C144853 Deformity, hypoplasia, or asymmetry able to be remediated by prosthesis (e.g., shoe insert) or covered by clothing Deformity, hypoplasia, or asymmetry able to be remediated by prosthesis (e.g., shoe insert) or covered by clothing Grade 2 Musculoskeletal Deformity, CTCAE Grade 2 Musculoskeletal deformity 10065783 C144853 Grade 2 Musculoskeletal deformity Grade 2 Musculoskeletal deformity Deformity, hypoplasia, or asymmetry able to be remediated by prosthesis (e.g., shoe insert) or covered by clothing NCI Deformity, hypoplasia, or asymmetry able to be remediated by prosthesis (e.g., shoe insert) or covered by clothing CTCAE_v5 Grade 2 Musculoskeletal Deformity, CTCAE PT NCI Grade 2 Musculoskeletal deformity PT CTCAE_v5 ctcae5:C144854 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Myalgia Grade 2 Myalgia, CTCAE 10028411 C144854 Grade 2 Myalgia Grade 2 Myalgia Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Myalgia PT CTCAE_v5 Grade 2 Myalgia, CTCAE PT NCI ctcae5:C144855 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Myasthenia Gravis, CTCAE Grade 2 Myasthenia gravis 10028417 C144855 Grade 2 Myasthenia gravis Grade 2 Myasthenia gravis Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Myasthenia Gravis, CTCAE PT NCI Grade 2 Myasthenia gravis PT CTCAE_v5 ctcae5:C144856 Asymptomatic and cardiac enzymes minimally abnormal and no evidence of ischemic ECG changes Asymptomatic and cardiac enzymes minimally abnormal and no evidence of ischemic ECG changes Grade 2 Myocardial Infarction, CTCAE Grade 2 Myocardial infarction 10028596 C144856 Grade 2 Myocardial infarction Grade 2 Myocardial infarction Asymptomatic and cardiac enzymes minimally abnormal and no evidence of ischemic ECG changes NCI Asymptomatic and cardiac enzymes minimally abnormal and no evidence of ischemic ECG changes CTCAE_v5 Grade 2 Myocardial Infarction, CTCAE PT NCI Grade 2 Myocardial infarction PT CTCAE_v5 ctcae5:C144857 Symptoms with moderate activity or exertion Symptoms with moderate activity or exertion Grade 2 Myocarditis Grade 2 Myocarditis, CTCAE 10028606 C144857 Grade 2 Myocarditis Grade 2 Myocarditis Symptoms with moderate activity or exertion NCI Symptoms with moderate activity or exertion CTCAE_v5 Grade 2 Myocarditis PT CTCAE_v5 Grade 2 Myocarditis, CTCAE PT NCI ctcae5:C144858 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Nail Infection, CTCAE Grade 2 Nail infection 10061304 C144858 Grade 2 Nail infection Grade 2 Nail infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Nail Infection, CTCAE PT NCI Grade 2 Nail infection PT CTCAE_v5 ctcae5:C144859 Symptomatic separation of the nail bed from the nail plate or nail loss; limiting instrumental ADL Symptomatic separation of the nail bed from the nail plate or nail loss; limiting instrumental ADL Grade 2 Nail Loss, CTCAE Grade 2 Nail loss 10049281 C144859 Grade 2 Nail loss Grade 2 Nail loss Symptomatic separation of the nail bed from the nail plate or nail loss; limiting instrumental ADL NCI Symptomatic separation of the nail bed from the nail plate or nail loss; limiting instrumental ADL CTCAE_v5 Grade 2 Nail Loss, CTCAE PT NCI Grade 2 Nail loss PT CTCAE_v5 ctcae5:C144860 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Nasal Congestion, CTCAE Grade 2 Nasal congestion 10028735 C144860 Grade 2 Nasal congestion Grade 2 Nasal congestion Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Nasal Congestion, CTCAE PT NCI Grade 2 Nasal congestion PT CTCAE_v5 ctcae5:C144861 Moderate neck edema; slight obliteration of anatomic landmarks; limiting instrumental ADL Moderate neck edema; slight obliteration of anatomic landmarks; limiting instrumental ADL Grade 2 Neck Edema, CTCAE Grade 2 Neck edema 10054482 C144861 Grade 2 Neck edema Grade 2 Neck edema Moderate neck edema; slight obliteration of anatomic landmarks; limiting instrumental ADL NCI Moderate neck edema; slight obliteration of anatomic landmarks; limiting instrumental ADL CTCAE_v5 Grade 2 Neck Edema, CTCAE PT NCI Grade 2 Neck edema PT CTCAE_v5 ctcae5:C144862 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Grade 2 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C144862 Grade 2 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Grade 2 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Grade 2 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C144863 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Nervous System Disorders - Other, Specify, CTCAE Grade 2 Nervous system disorders - Other, specify 10029205 C144863 Grade 2 Nervous system disorders - Other, specify Grade 2 Nervous system disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Nervous System Disorders - Other, Specify, CTCAE PT NCI Grade 2 Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C144864 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Neuralgia Grade 2 Neuralgia, CTCAE 10029223 C144864 Grade 2 Neuralgia Grade 2 Neuralgia Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Neuralgia PT CTCAE_v5 Grade 2 Neuralgia, CTCAE PT NCI ctcae5:C144865 <1500-1000/mm3; <1.5-1.0 x 10e9/L <1500-1000/mm3; <1.5-1.0 x 10e9/L Grade 2 Neutrophil Count Decreased, CTCAE Grade 2 Neutrophil count decreased 10029366 C144865 Grade 2 Neutrophil count decreased Grade 2 Neutrophil count decreased <1500-1000/mm3; <1.5-1.0 x 10e9/L NCI <1500-1000/mm3; <1.5-1.0 x 10e9/L CTCAE_v5 Grade 2 Neutrophil Count Decreased, CTCAE PT NCI Grade 2 Neutrophil count decreased PT CTCAE_v5 ctcae5:C144866 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Grade 2 Night Blindness, CTCAE Grade 2 Night blindness 10029404 C144866 Grade 2 Night blindness Grade 2 Night blindness Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL CTCAE_v5 Grade 2 Night Blindness, CTCAE PT NCI Grade 2 Night blindness PT CTCAE_v5 ctcae5:C144867 Symptomatic; asymmetry of nipple areolar complex with moderate retraction and/or thickening of the nipple areolar complex Symptomatic; asymmetry of nipple areolar complex with moderate retraction and/or thickening of the nipple areolar complex Grade 2 Nipple Deformity, CTCAE Grade 2 Nipple deformity 10065823 C144867 Grade 2 Nipple deformity Grade 2 Nipple deformity Symptomatic; asymmetry of nipple areolar complex with moderate retraction and/or thickening of the nipple areolar complex NCI Symptomatic; asymmetry of nipple areolar complex with moderate retraction and/or thickening of the nipple areolar complex CTCAE_v5 Grade 2 Nipple Deformity, CTCAE PT NCI Grade 2 Nipple deformity PT CTCAE_v5 ctcae5:C144868 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Non-Cardiac Chest Pain, CTCAE Grade 2 Non-cardiac chest pain 10062501 C144868 Grade 2 Non-cardiac chest pain Grade 2 Non-cardiac chest pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Non-Cardiac Chest Pain, CTCAE PT NCI Grade 2 Non-cardiac chest pain PT CTCAE_v5 ctcae5:C144869 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Obstruction Gastric, CTCAE Grade 2 Obstruction gastric 10029957 C144869 Grade 2 Obstruction gastric Grade 2 Obstruction gastric Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Obstruction Gastric, CTCAE PT NCI Grade 2 Obstruction gastric PT CTCAE_v5 ctcae5:C144870 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Oculomotor Nerve Disorder, CTCAE Grade 2 Oculomotor nerve disorder 10053661 C144870 Grade 2 Oculomotor nerve disorder Grade 2 Oculomotor nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Oculomotor Nerve Disorder, CTCAE PT NCI Grade 2 Oculomotor nerve disorder PT CTCAE_v5 ctcae5:C144871 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Olfactory Nerve Disorder, CTCAE Grade 2 Olfactory nerve disorder 10056388 C144871 Grade 2 Olfactory nerve disorder Grade 2 Olfactory nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Olfactory Nerve Disorder, CTCAE PT NCI Grade 2 Olfactory nerve disorder PT CTCAE_v5 ctcae5:C144872 Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Optic Nerve Disorder, CTCAE Grade 2 Optic nerve disorder 10061322 C144872 Grade 2 Optic nerve disorder Grade 2 Optic nerve disorder Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Optic Nerve Disorder, CTCAE PT NCI Grade 2 Optic nerve disorder PT CTCAE_v5 ctcae5:C144873 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Oral Cavity Fistula, CTCAE Grade 2 Oral cavity fistula 10065720 C144873 Grade 2 Oral cavity fistula Grade 2 Oral cavity fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Oral Cavity Fistula, CTCAE PT NCI Grade 2 Oral cavity fistula PT CTCAE_v5 ctcae5:C144874 Moderate pain; interfering with oral intake Moderate pain; interfering with oral intake Grade 2 Oral Dysesthesia, CTCAE Grade 2 Oral dysesthesia 10054520 C144874 Grade 2 Oral dysesthesia Grade 2 Oral dysesthesia Moderate pain; interfering with oral intake NCI Moderate pain; interfering with oral intake CTCAE_v5 Grade 2 Oral Dysesthesia, CTCAE PT NCI Grade 2 Oral dysesthesia PT CTCAE_v5 ctcae5:C144877 Moderate pain; altered oral intake; non-narcotics initiated; topical analgesics initiated Moderate pain; altered oral intake; non-narcotics initiated; topical analgesics initiated Grade 2 Oropharyngeal Pain, CTCAE Grade 2 Oropharyngeal pain 10068319 C144877 Grade 2 Oropharyngeal pain Grade 2 Oropharyngeal pain Moderate pain; altered oral intake; non-narcotics initiated; topical analgesics initiated NCI Moderate pain; altered oral intake; non-narcotics initiated; topical analgesics initiated CTCAE_v5 Grade 2 Oropharyngeal Pain, CTCAE PT NCI Grade 2 Oropharyngeal pain PT CTCAE_v5 ctcae5:C144878 Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL Grade 2 Osteonecrosis of Jaw, CTCAE Grade 2 Osteonecrosis of jaw 10064658 C144878 Grade 2 Osteonecrosis of jaw Grade 2 Osteonecrosis of jaw Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL NCI Symptomatic; medical intervention indicated (e.g., topical agents); limiting instrumental ADL CTCAE_v5 Grade 2 Osteonecrosis of Jaw, CTCAE PT NCI Grade 2 Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C144879 Symptomatic; medical intervention indicated (e.g., analgesics or bisphosphonates); limiting instrumental ADL Symptomatic; medical intervention indicated (e.g., analgesics or bisphosphonates); limiting instrumental ADL Grade 2 Osteonecrosis Grade 2 Osteonecrosis, CTCAE 10031264 C144879 Grade 2 Osteonecrosis Grade 2 Osteonecrosis Symptomatic; medical intervention indicated (e.g., analgesics or bisphosphonates); limiting instrumental ADL NCI Symptomatic; medical intervention indicated (e.g., analgesics or bisphosphonates); limiting instrumental ADL CTCAE_v5 Grade 2 Osteonecrosis PT CTCAE_v5 Grade 2 Osteonecrosis, CTCAE PT NCI ctcae5:C144880 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Otitis Externa, CTCAE Grade 2 Otitis externa 10033072 C144880 Grade 2 Otitis externa Grade 2 Otitis externa Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Otitis Externa, CTCAE PT NCI Grade 2 Otitis externa PT CTCAE_v5 ctcae5:C144881 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Otitis Media, CTCAE Grade 2 Otitis media 10033078 C144881 Grade 2 Otitis media Grade 2 Otitis media Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Otitis Media, CTCAE PT NCI Grade 2 Otitis media PT CTCAE_v5 ctcae5:C144883 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Ovarian Infection, CTCAE Grade 2 Ovarian infection 10055005 C144883 Grade 2 Ovarian infection Grade 2 Ovarian infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Ovarian Infection, CTCAE PT NCI Grade 2 Ovarian infection PT CTCAE_v5 ctcae5:C144884 Symptomatic and intervention not indicated Symptomatic and intervention not indicated Grade 2 Ovarian Rupture, CTCAE Grade 2 Ovarian rupture 10033279 C144884 Grade 2 Ovarian rupture Grade 2 Ovarian rupture Symptomatic and intervention not indicated NCI Symptomatic and intervention not indicated CTCAE_v5 Grade 2 Ovarian Rupture, CTCAE PT NCI Grade 2 Ovarian rupture PT CTCAE_v5 ctcae5:C144886 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pain In Extremity, CTCAE Grade 2 Pain in extremity 10033425 C144886 Grade 2 Pain in extremity Grade 2 Pain in extremity Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pain In Extremity, CTCAE PT NCI Grade 2 Pain in extremity PT CTCAE_v5 ctcae5:C144887 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pain of Skin, CTCAE Grade 2 Pain of skin 10033474 C144887 Grade 2 Pain of skin Grade 2 Pain of skin Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pain of Skin, CTCAE PT NCI Grade 2 Pain of skin PT CTCAE_v5 ctcae5:C144888 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pain Grade 2 Pain, CTCAE 10033371 C144888 Grade 2 Pain Grade 2 Pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pain PT CTCAE_v5 Grade 2 Pain, CTCAE PT NCI ctcae5:C144889 Skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL Skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL Grade 2 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE Grade 2 Palmar-plantar erythrodysesthesia syndrome 10054524 C144889 Grade 2 Palmar-plantar erythrodysesthesia syndrome Grade 2 Palmar-plantar erythrodysesthesia syndrome Skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL NCI Skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL CTCAE_v5 Grade 2 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE PT NCI Grade 2 Palmar-plantar erythrodysesthesia syndrome PT CTCAE_v5 ctcae5:C144890 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Pancreatic Anastomotic Leak, CTCAE Grade 2 Pancreatic anastomotic leak 10050457 C144890 Grade 2 Pancreatic anastomotic leak Grade 2 Pancreatic anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Pancreatic Anastomotic Leak, CTCAE PT NCI Grade 2 Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C144891 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Pancreatic Duct Stenosis, CTCAE Grade 2 Pancreatic duct stenosis 10065703 C144891 Grade 2 Pancreatic duct stenosis Grade 2 Pancreatic duct stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Pancreatic Duct Stenosis, CTCAE PT NCI Grade 2 Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C144892 Increase in stool frequency, bulk, or odor; steatorrhea Increase in stool frequency, bulk, or odor; steatorrhea Grade 2 Pancreatic Enzymes Decreased, CTCAE Grade 2 Pancreatic enzymes decreased 10062646 C144892 Grade 2 Pancreatic enzymes decreased Grade 2 Pancreatic enzymes decreased Increase in stool frequency, bulk, or odor; steatorrhea NCI Increase in stool frequency, bulk, or odor; steatorrhea CTCAE_v5 Grade 2 Pancreatic Enzymes Decreased, CTCAE PT NCI Grade 2 Pancreatic enzymes decreased PT CTCAE_v5 ctcae5:C144895 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Papilledema Grade 2 Papilledema, CTCAE 10033703 C144895 Grade 2 Papilledema Grade 2 Papilledema Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Papilledema PT CTCAE_v5 Grade 2 Papilledema, CTCAE PT NCI ctcae5:C144896 Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms Grade 2 Papulopustular Rash, CTCAE Grade 2 Papulopustular rash 10069138 C144896 Grade 2 Papulopustular rash Grade 2 Papulopustular rash Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms NCI Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms CTCAE_v5 Grade 2 Papulopustular Rash, CTCAE PT NCI Grade 2 Papulopustular rash PT CTCAE_v5 ctcae5:C144897 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Paresthesia Grade 2 Paresthesia, CTCAE 10033987 C144897 Grade 2 Paresthesia Grade 2 Paresthesia Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Paresthesia PT CTCAE_v5 Grade 2 Paresthesia, CTCAE PT NCI ctcae5:C144898 Local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, antiviral); nail fold edema or erythema with pain; associated with discharge or nail plate separation; limiting instrumental ADL Local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, antiviral); nail fold edema or erythema with pain; associated with discharge or nail plate separation; limiting instrumental ADL Grade 2 Paronychia Grade 2 Paronychia, CTCAE 10034016 C144898 Grade 2 Paronychia Grade 2 Paronychia Local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, antiviral); nail fold edema or erythema with pain; associated with discharge or nail plate separation; limiting instrumental ADL NCI Local intervention indicated; oral intervention indicated (e.g., antibiotic, antifungal, antiviral); nail fold edema or erythema with pain; associated with discharge or nail plate separation; limiting instrumental ADL CTCAE_v5 Grade 2 Paronychia PT CTCAE_v5 Grade 2 Paronychia, CTCAE PT NCI ctcae5:C144899 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Paroxysmal Atrial Tachycardia, CTCAE Grade 2 Paroxysmal atrial tachycardia 10034040 C144899 Grade 2 Paroxysmal atrial tachycardia Grade 2 Paroxysmal atrial tachycardia Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Grade 2 Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C144900 Symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental ADL Symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental ADL Grade 2 Pelvic Floor Muscle Weakness, CTCAE Grade 2 Pelvic floor muscle weakness 10064026 C144900 Grade 2 Pelvic floor muscle weakness Grade 2 Pelvic floor muscle weakness Symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental ADL NCI Symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental ADL CTCAE_v5 Grade 2 Pelvic Floor Muscle Weakness, CTCAE PT NCI Grade 2 Pelvic floor muscle weakness PT CTCAE_v5 ctcae5:C144901 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Pelvic Infection, CTCAE Grade 2 Pelvic infection 10058674 C144901 Grade 2 Pelvic infection Grade 2 Pelvic infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Pelvic Infection, CTCAE PT NCI Grade 2 Pelvic infection PT CTCAE_v5 ctcae5:C144902 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pelvic Pain, CTCAE Grade 2 Pelvic pain 10034263 C144902 Grade 2 Pelvic pain Grade 2 Pelvic pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pelvic Pain, CTCAE PT NCI Grade 2 Pelvic pain PT CTCAE_v5 ctcae5:C144903 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Penile Infection, CTCAE Grade 2 Penile infection 10061912 C144903 Grade 2 Penile infection Grade 2 Penile infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Penile Infection, CTCAE PT NCI Grade 2 Penile infection PT CTCAE_v5 ctcae5:C144905 Asymptomatic effusion size small to moderate Asymptomatic effusion size small to moderate Grade 2 Pericardial Effusion, CTCAE Grade 2 Pericardial effusion 10034474 C144905 Grade 2 Pericardial effusion Grade 2 Pericardial effusion Asymptomatic effusion size small to moderate NCI Asymptomatic effusion size small to moderate CTCAE_v5 Grade 2 Pericardial Effusion, CTCAE PT NCI Grade 2 Pericardial effusion PT CTCAE_v5 ctcae5:C144906 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Perineal Pain, CTCAE Grade 2 Perineal pain 10061339 C144906 Grade 2 Perineal pain Grade 2 Perineal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Perineal Pain, CTCAE PT NCI Grade 2 Perineal pain PT CTCAE_v5 ctcae5:C144907 Indurated or pitting edema; topical intervention indicated Indurated or pitting edema; topical intervention indicated Grade 2 Periorbital Edema, CTCAE Grade 2 Periorbital edema 10054541 C144907 Grade 2 Periorbital edema Grade 2 Periorbital edema Indurated or pitting edema; topical intervention indicated NCI Indurated or pitting edema; topical intervention indicated CTCAE_v5 Grade 2 Periorbital Edema, CTCAE PT NCI Grade 2 Periorbital edema PT CTCAE_v5 ctcae5:C144908 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Periorbital Infection, CTCAE Grade 2 Periorbital infection 10051472 C144908 Grade 2 Periorbital infection Grade 2 Periorbital infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Periorbital Infection, CTCAE PT NCI Grade 2 Periorbital infection PT CTCAE_v5 ctcae5:C144909 Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit Grade 2 Peripheral Ischemia, CTCAE Grade 2 Peripheral ischemia 10034578 C144909 Grade 2 Peripheral ischemia Grade 2 Peripheral ischemia Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit NCI Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit CTCAE_v5 Grade 2 Peripheral Ischemia, CTCAE PT NCI Grade 2 Peripheral ischemia PT CTCAE_v5 ctcae5:C144910 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Peripheral Motor Neuropathy, CTCAE Grade 2 Peripheral motor neuropathy 10034580 C144910 Grade 2 Peripheral motor neuropathy Grade 2 Peripheral motor neuropathy Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Peripheral Motor Neuropathy, CTCAE PT NCI Grade 2 Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C144911 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Peripheral Nerve Infection, CTCAE Grade 2 Peripheral nerve infection 10065766 C144911 Grade 2 Peripheral nerve infection Grade 2 Peripheral nerve infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Peripheral Nerve Infection, CTCAE PT NCI Grade 2 Peripheral nerve infection PT CTCAE_v5 ctcae5:C144912 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Peripheral Sensory Neuropathy, CTCAE Grade 2 Peripheral sensory neuropathy 10034620 C144912 Grade 2 Peripheral sensory neuropathy Grade 2 Peripheral sensory neuropathy Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Peripheral Sensory Neuropathy, CTCAE PT NCI Grade 2 Peripheral sensory neuropathy PT CTCAE_v5 ctcae5:C144913 Moderate personality change Moderate personality change Grade 2 Personality Change, CTCAE Grade 2 Personality change 10034719 C144913 Grade 2 Personality change Grade 2 Personality change Moderate personality change NCI Moderate personality change CTCAE_v5 Grade 2 Personality Change, CTCAE PT NCI Grade 2 Personality change PT CTCAE_v5 ctcae5:C144914 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Phantom Pain, CTCAE Grade 2 Phantom pain 10056238 C144914 Grade 2 Phantom pain Grade 2 Phantom pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Phantom Pain, CTCAE PT NCI Grade 2 Phantom pain PT CTCAE_v5 ctcae5:C144915 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Pharyngeal Anastomotic Leak, CTCAE Grade 2 Pharyngeal anastomotic leak 10065705 C144915 Grade 2 Pharyngeal anastomotic leak Grade 2 Pharyngeal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Pharyngeal Anastomotic Leak, CTCAE PT NCI Grade 2 Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C144918 Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL Grade 2 Pharyngeal Mucositis, CTCAE Grade 2 Pharyngeal mucositis 10065881 C144918 Grade 2 Pharyngeal mucositis Grade 2 Pharyngeal mucositis Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL NCI Moderate pain, analgesics indicated; altered oral intake; limiting instrumental ADL CTCAE_v5 Grade 2 Pharyngeal Mucositis, CTCAE PT NCI Grade 2 Pharyngeal mucositis PT CTCAE_v5 ctcae5:C144919 Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Grade 2 Pharyngeal Stenosis, CTCAE Grade 2 Pharyngeal stenosis 10050028 C144919 Grade 2 Pharyngeal stenosis Grade 2 Pharyngeal stenosis Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL NCI Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL CTCAE_v5 Grade 2 Pharyngeal Stenosis, CTCAE PT NCI Grade 2 Pharyngeal stenosis PT CTCAE_v5 ctcae5:C144920 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Pharyngitis Grade 2 Pharyngitis, CTCAE 10034835 C144920 Grade 2 Pharyngitis Grade 2 Pharyngitis Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Pharyngitis PT CTCAE_v5 Grade 2 Pharyngitis, CTCAE PT NCI ctcae5:C144921 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pharyngolaryngeal Pain, CTCAE Grade 2 Pharyngolaryngeal pain 10034844 C144921 Grade 2 Pharyngolaryngeal pain Grade 2 Pharyngolaryngeal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pharyngolaryngeal Pain, CTCAE PT NCI Grade 2 Pharyngolaryngeal pain PT CTCAE_v5 ctcae5:C144922 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Phlebitis Infective, CTCAE Grade 2 Phlebitis infective 10056627 C144922 Grade 2 Phlebitis infective Grade 2 Phlebitis infective Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Phlebitis Infective, CTCAE PT NCI Grade 2 Phlebitis infective PT CTCAE_v5 ctcae5:C144923 Present Present Grade 2 Phlebitis Grade 2 Phlebitis, CTCAE 10034879 C144923 Grade 2 Phlebitis Grade 2 Phlebitis Present NCI Present CTCAE_v5 Grade 2 Phlebitis PT CTCAE_v5 Grade 2 Phlebitis, CTCAE PT NCI ctcae5:C144924 <75,000-50,000/mm3; <75.0-50.0 x 10e9/L <75,000-50,000/mm3; <75.0-50.0 x 10e9/L Grade 2 Platelet Count Decreased, CTCAE Grade 2 Platelet count decreased 10035528 C144924 Grade 2 Platelet count decreased Grade 2 Platelet count decreased <75,000-50,000/mm3; <75.0-50.0 x 10e9/L NCI <75,000-50,000/mm3; <75.0-50.0 x 10e9/L CTCAE_v5 Grade 2 Platelet Count Decreased, CTCAE PT NCI Grade 2 Platelet count decreased PT CTCAE_v5 ctcae5:C144925 Symptomatic; intervention indicated (e.g., diuretics or therapeutic thoracentesis) Symptomatic; intervention indicated (e.g., diuretics or therapeutic thoracentesis) Grade 2 Pleural Effusion, CTCAE Grade 2 Pleural effusion 10035598 C144925 Grade 2 Pleural effusion Grade 2 Pleural effusion Symptomatic; intervention indicated (e.g., diuretics or therapeutic thoracentesis) NCI Symptomatic; intervention indicated (e.g., diuretics or therapeutic thoracentesis) CTCAE_v5 Grade 2 Pleural Effusion, CTCAE PT NCI Grade 2 Pleural effusion PT CTCAE_v5 ctcae5:C144927 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Pleural Infection, CTCAE Grade 2 Pleural infection 10061351 C144927 Grade 2 Pleural infection Grade 2 Pleural infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Pleural Infection, CTCAE PT NCI Grade 2 Pleural infection PT CTCAE_v5 ctcae5:C144928 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Pleuritic Pain, CTCAE Grade 2 Pleuritic pain 10035623 C144928 Grade 2 Pleuritic pain Grade 2 Pleuritic pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Pleuritic Pain, CTCAE PT NCI Grade 2 Pleuritic pain PT CTCAE_v5 ctcae5:C144929 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Pneumonitis Grade 2 Pneumonitis, CTCAE 10035742 C144929 Grade 2 Pneumonitis Grade 2 Pneumonitis Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Pneumonitis PT CTCAE_v5 Grade 2 Pneumonitis, CTCAE PT NCI ctcae5:C144930 Decreased portal vein flow Decreased portal vein flow Grade 2 Portal Hypertension, CTCAE Grade 2 Portal hypertension 10036200 C144930 Grade 2 Portal hypertension Grade 2 Portal hypertension Decreased portal vein flow NCI Decreased portal vein flow CTCAE_v5 Grade 2 Portal Hypertension, CTCAE PT NCI Grade 2 Portal hypertension PT CTCAE_v5 ctcae5:C144931 Intervention not indicated Intervention not indicated Grade 2 Portal Vein Thrombosis, CTCAE Grade 2 Portal vein thrombosis 10036206 C144931 Grade 2 Portal vein thrombosis Grade 2 Portal vein thrombosis Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 2 Portal Vein Thrombosis, CTCAE PT NCI Grade 2 Portal vein thrombosis PT CTCAE_v5 ctcae5:C144932 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Postnasal Drip, CTCAE Grade 2 Postnasal drip 10036402 C144932 Grade 2 Postnasal drip Grade 2 Postnasal drip Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Postnasal Drip, CTCAE PT NCI Grade 2 Postnasal drip PT CTCAE_v5 ctcae5:C144933 Moderate bleeding requiring transfusion < 2 units (10 cc/kg for pediatrics) of pRBCs Moderate bleeding requiring transfusion < 2 units (10 cc/kg for pediatrics) of pRBCs Grade 2 Postoperative Hemorrhage, CTCAE Grade 2 Postoperative hemorrhage 10055322 C144933 Grade 2 Postoperative hemorrhage Grade 2 Postoperative hemorrhage Moderate bleeding requiring transfusion < 2 units (10 cc/kg for pediatrics) of pRBCs NCI Moderate bleeding requiring transfusion < 2 units (10 cc/kg for pediatrics) of pRBCs CTCAE_v5 Grade 2 Postoperative Hemorrhage, CTCAE PT NCI Grade 2 Postoperative hemorrhage PT CTCAE_v5 ctcae5:C144934 Extubated within 24-72 hrs postoperatively Extubated within 24-72 hrs postoperatively Grade 2 Postoperative Thoracic Procedure Complication, CTCAE Grade 2 Postoperative thoracic procedure complication 10056745 C144934 Grade 2 Postoperative thoracic procedure complication Grade 2 Postoperative thoracic procedure complication Extubated within 24-72 hrs postoperatively NCI Extubated within 24-72 hrs postoperatively CTCAE_v5 Grade 2 Postoperative Thoracic Procedure Complication, CTCAE PT NCI Grade 2 Postoperative thoracic procedure complication PT CTCAE_v5 ctcae5:C144935 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Grade 2 Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C144935 Grade 2 Pregnancy, puerperium and perinatal conditions - Other, specify Grade 2 Pregnancy, puerperium and perinatal conditions - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Grade 2 Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C144936 Delivery of a liveborn infant at >28 to 34 weeks gestation Delivery of a liveborn infant at >28 to 34 weeks gestation Grade 2 Premature Delivery, CTCAE Grade 2 Premature delivery 10036595 C144936 Grade 2 Premature delivery Grade 2 Premature delivery Delivery of a liveborn infant at >28 to 34 weeks gestation NCI Delivery of a liveborn infant at >28 to 34 weeks gestation CTCAE_v5 Grade 2 Premature Delivery, CTCAE PT NCI Grade 2 Premature delivery PT CTCAE_v5 ctcae5:C144937 Present Present Grade 2 Premature Menopause, CTCAE Grade 2 Premature menopause 10036601 C144937 Grade 2 Premature menopause Grade 2 Premature menopause Present NCI Present CTCAE_v5 Grade 2 Premature Menopause, CTCAE PT NCI Grade 2 Premature menopause PT CTCAE_v5 ctcae5:C144938 Present (e.g., near fainting) Present (e.g., near fainting) Grade 2 Presyncope Grade 2 Presyncope, CTCAE 10036653 C144938 Grade 2 Presyncope Grade 2 Presyncope Present (e.g., near fainting) NCI Present (e.g., near fainting) CTCAE_v5 Grade 2 Presyncope PT CTCAE_v5 Grade 2 Presyncope, CTCAE PT NCI ctcae5:C144939 Moderate sputum production; limiting instrumental ADL Moderate sputum production; limiting instrumental ADL Grade 2 Productive Cough, CTCAE Grade 2 Productive cough 10036790 C144939 Grade 2 Productive cough Grade 2 Productive cough Moderate sputum production; limiting instrumental ADL NCI Moderate sputum production; limiting instrumental ADL CTCAE_v5 Grade 2 Productive Cough, CTCAE PT NCI Grade 2 Productive cough PT CTCAE_v5 ctcae5:C144940 Recurrent after manual reduction; local irritation or stool leakage; difficulty to fit appliance; limiting instrumental ADL Recurrent after manual reduction; local irritation or stool leakage; difficulty to fit appliance; limiting instrumental ADL Grade 2 Prolapse of Intestinal Stoma, CTCAE Grade 2 Prolapse of intestinal stoma 10065745 C144940 Grade 2 Prolapse of intestinal stoma Grade 2 Prolapse of intestinal stoma Recurrent after manual reduction; local irritation or stool leakage; difficulty to fit appliance; limiting instrumental ADL NCI Recurrent after manual reduction; local irritation or stool leakage; difficulty to fit appliance; limiting instrumental ADL CTCAE_v5 Grade 2 Prolapse of Intestinal Stoma, CTCAE PT NCI Grade 2 Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C144941 Local care or maintenance; minor revision indicated Local care or maintenance; minor revision indicated Grade 2 Prolapse of Urostomy, CTCAE Grade 2 Prolapse of urostomy 10065822 C144941 Grade 2 Prolapse of urostomy Grade 2 Prolapse of urostomy Local care or maintenance; minor revision indicated NCI Local care or maintenance; minor revision indicated CTCAE_v5 Grade 2 Prolapse of Urostomy, CTCAE PT NCI Grade 2 Prolapse of urostomy PT CTCAE_v5 ctcae5:C144942 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Prostate Infection, CTCAE Grade 2 Prostate infection 10050662 C144942 Grade 2 Prostate infection Grade 2 Prostate infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Prostate Infection, CTCAE PT NCI Grade 2 Prostate infection PT CTCAE_v5 ctcae5:C144944 Symptomatic; elective intervention indicated Symptomatic; elective intervention indicated Grade 2 Prostatic Obstruction, CTCAE Grade 2 Prostatic obstruction 10055026 C144944 Grade 2 Prostatic obstruction Grade 2 Prostatic obstruction Symptomatic; elective intervention indicated NCI Symptomatic; elective intervention indicated CTCAE_v5 Grade 2 Prostatic Obstruction, CTCAE PT NCI Grade 2 Prostatic obstruction PT CTCAE_v5 ctcae5:C144945 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Prostatic Pain, CTCAE Grade 2 Prostatic pain 10036968 C144945 Grade 2 Prostatic pain Grade 2 Prostatic pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Prostatic Pain, CTCAE PT NCI Grade 2 Prostatic pain PT CTCAE_v5 ctcae5:C144946 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Psychiatric Disorders - Other, Specify, CTCAE Grade 2 Psychiatric disorders - Other, specify 10037175 C144946 Grade 2 Psychiatric disorders - Other, specify Grade 2 Psychiatric disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Psychiatric Disorders - Other, Specify, CTCAE PT NCI Grade 2 Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C144947 Moderate psychotic symptoms (e.g., disorganized speech; impaired reality testing) Moderate psychotic symptoms (e.g., disorganized speech; impaired reality testing) Grade 2 Psychosis Grade 2 Psychosis, CTCAE 10037234 C144947 Grade 2 Psychosis Grade 2 Psychosis Moderate psychotic symptoms (e.g., disorganized speech; impaired reality testing) NCI Moderate psychotic symptoms (e.g., disorganized speech; impaired reality testing) CTCAE_v5 Grade 2 Psychosis PT CTCAE_v5 Grade 2 Psychosis, CTCAE PT NCI ctcae5:C144948 Moderate dyspnea on exertion; medical intervention indicated; limiting instrumental ADL Moderate dyspnea on exertion; medical intervention indicated; limiting instrumental ADL Grade 2 Pulmonary Edema, CTCAE Grade 2 Pulmonary edema 10037375 C144948 Grade 2 Pulmonary edema Grade 2 Pulmonary edema Moderate dyspnea on exertion; medical intervention indicated; limiting instrumental ADL NCI Moderate dyspnea on exertion; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Pulmonary Edema, CTCAE PT NCI Grade 2 Pulmonary edema PT CTCAE_v5 ctcae5:C144949 Evidence of pulmonary hypertension; radiographic pulmonary fibrosis 25-50% associated with hypoxia Evidence of pulmonary hypertension; radiographic pulmonary fibrosis 25-50% associated with hypoxia Grade 2 Pulmonary Fibrosis, CTCAE Grade 2 Pulmonary fibrosis 10037383 C144949 Grade 2 Pulmonary fibrosis Grade 2 Pulmonary fibrosis Evidence of pulmonary hypertension; radiographic pulmonary fibrosis 25-50% associated with hypoxia NCI Evidence of pulmonary hypertension; radiographic pulmonary fibrosis 25-50% associated with hypoxia CTCAE_v5 Grade 2 Pulmonary Fibrosis, CTCAE PT NCI Grade 2 Pulmonary fibrosis PT CTCAE_v5 ctcae5:C144950 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Pulmonary Fistula, CTCAE Grade 2 Pulmonary fistula 10065873 C144950 Grade 2 Pulmonary fistula Grade 2 Pulmonary fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Pulmonary Fistula, CTCAE PT NCI Grade 2 Pulmonary fistula PT CTCAE_v5 ctcae5:C144951 Asymptomatic; moderate regurgitation or stenosis by imaging Asymptomatic; moderate regurgitation or stenosis by imaging Grade 2 Pulmonary Valve Disease, CTCAE Grade 2 Pulmonary valve disease 10061541 C144951 Grade 2 Pulmonary valve disease Grade 2 Pulmonary valve disease Asymptomatic; moderate regurgitation or stenosis by imaging NCI Asymptomatic; moderate regurgitation or stenosis by imaging CTCAE_v5 Grade 2 Pulmonary Valve Disease, CTCAE PT NCI Grade 2 Pulmonary valve disease PT CTCAE_v5 ctcae5:C144952 Combined area of lesions covering 10-30% BSA; bleeding with trauma Combined area of lesions covering 10-30% BSA; bleeding with trauma Grade 2 Purpura Grade 2 Purpura, CTCAE 10037549 C144952 Grade 2 Purpura Grade 2 Purpura Combined area of lesions covering 10-30% BSA; bleeding with trauma NCI Combined area of lesions covering 10-30% BSA; bleeding with trauma CTCAE_v5 Grade 2 Purpura PT CTCAE_v5 Grade 2 Purpura, CTCAE PT NCI ctcae5:C144953 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Pyramidal Tract Syndrome, CTCAE Grade 2 Pyramidal tract syndrome 10063636 C144953 Grade 2 Pyramidal tract syndrome Grade 2 Pyramidal tract syndrome Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Pyramidal Tract Syndrome, CTCAE PT NCI Grade 2 Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C144954 Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema Grade 2 Radiation Recall Reaction (Dermatologic), CTCAE Grade 2 Radiation recall reaction (dermatologic) 10037767 C144954 Grade 2 Radiation recall reaction (dermatologic) Grade 2 Radiation recall reaction (dermatologic) Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema NCI Moderate to brisk erythema; patchy moist desquamation, mostly confined to skin folds and creases; moderate edema CTCAE_v5 Grade 2 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Grade 2 Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C144955 Moderate symptoms; medical intervention indicated; limiting instrumental ADL Moderate symptoms; medical intervention indicated; limiting instrumental ADL Grade 2 Radiculitis Grade 2 Radiculitis, CTCAE 10061928 C144955 Grade 2 Radiculitis Grade 2 Radiculitis Moderate symptoms; medical intervention indicated; limiting instrumental ADL NCI Moderate symptoms; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Radiculitis PT CTCAE_v5 Grade 2 Radiculitis, CTCAE PT NCI ctcae5:C144956 Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms Grade 2 Rash Acneiform, CTCAE Grade 2 Rash acneiform 10037847 C144956 Grade 2 Rash acneiform Grade 2 Rash acneiform Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms NCI Papules and/or pustules covering 10-30% BSA, which may or may not be associated with symptoms of pruritus or tenderness; associated with psychosocial impact; limiting instrumental ADL; papules and/or pustules covering > 30% BSA with or without mild symptoms CTCAE_v5 Grade 2 Rash Acneiform, CTCAE PT NCI Grade 2 Rash acneiform PT CTCAE_v5 ctcae5:C144957 Macules/papules covering 10-30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental ADL; rash covering > 30% BSA with or without mild symptoms Macules/papules covering 10-30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental ADL; rash covering > 30% BSA with or without mild symptoms Grade 2 Rash Maculo-Papular, CTCAE Grade 2 Rash maculo-papular 10037868 C144957 Grade 2 Rash maculo-papular Grade 2 Rash maculo-papular Macules/papules covering 10-30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental ADL; rash covering > 30% BSA with or without mild symptoms NCI Macules/papules covering 10-30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental ADL; rash covering > 30% BSA with or without mild symptoms CTCAE_v5 Grade 2 Rash Maculo-Papular, CTCAE PT NCI Grade 2 Rash maculo-papular PT CTCAE_v5 ctcae5:C144958 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Rash Pustular, CTCAE Grade 2 Rash pustular 10037888 C144958 Grade 2 Rash pustular Grade 2 Rash pustular Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Rash Pustular, CTCAE PT NCI Grade 2 Rash pustular PT CTCAE_v5 ctcae5:C144959 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Rectal Anastomotic Leak, CTCAE Grade 2 Rectal anastomotic leak 10065894 C144959 Grade 2 Rectal anastomotic leak Grade 2 Rectal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Rectal Anastomotic Leak, CTCAE PT NCI Grade 2 Rectal anastomotic leak PT CTCAE_v5 ctcae5:C144960 Symptomatic Symptomatic Grade 2 Rectal Fissure, CTCAE Grade 2 Rectal fissure 10064993 C144960 Grade 2 Rectal fissure Grade 2 Rectal fissure Symptomatic NCI Symptomatic CTCAE_v5 Grade 2 Rectal Fissure, CTCAE PT NCI Grade 2 Rectal fissure PT CTCAE_v5 ctcae5:C144963 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Rectal Mucositis, CTCAE Grade 2 Rectal mucositis 10063190 C144963 Grade 2 Rectal mucositis Grade 2 Rectal mucositis Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Rectal Mucositis, CTCAE PT NCI Grade 2 Rectal mucositis PT CTCAE_v5 ctcae5:C144965 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Rectal Pain, CTCAE Grade 2 Rectal pain 10038072 C144965 Grade 2 Rectal pain Grade 2 Rectal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Rectal Pain, CTCAE PT NCI Grade 2 Rectal pain PT CTCAE_v5 ctcae5:C144967 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Rectal Stenosis, CTCAE Grade 2 Rectal stenosis 10038079 C144967 Grade 2 Rectal stenosis Grade 2 Rectal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Rectal Stenosis, CTCAE PT NCI Grade 2 Rectal stenosis PT CTCAE_v5 ctcae5:C144969 Moderate symptoms Moderate symptoms Grade 2 Recurrent Laryngeal Nerve Palsy, CTCAE Grade 2 Recurrent laryngeal nerve palsy 10038130 C144969 Grade 2 Recurrent laryngeal nerve palsy Grade 2 Recurrent laryngeal nerve palsy Moderate symptoms NCI Moderate symptoms CTCAE_v5 Grade 2 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Grade 2 Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C144970 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Renal and Urinary Disorders - Other, Specify, CTCAE Grade 2 Renal and urinary disorders - Other, specify 10038359 C144970 Grade 2 Renal and urinary disorders - Other, specify Grade 2 Renal and urinary disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Grade 2 Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C144971 Symptomatic; oral antiemetics indicated; around the clock nonprescription analgesics or any oral narcotic analgesics indicated Symptomatic; oral antiemetics indicated; around the clock nonprescription analgesics or any oral narcotic analgesics indicated Grade 2 Renal Calculi, CTCAE Grade 2 Renal calculi 10038385 C144971 Grade 2 Renal calculi Grade 2 Renal calculi Symptomatic; oral antiemetics indicated; around the clock nonprescription analgesics or any oral narcotic analgesics indicated NCI Symptomatic; oral antiemetics indicated; around the clock nonprescription analgesics or any oral narcotic analgesics indicated CTCAE_v5 Grade 2 Renal Calculi, CTCAE PT NCI Grade 2 Renal calculi PT CTCAE_v5 ctcae5:C144972 Moderate pain; limiting instrumental ADL; prescription medication indicated Moderate pain; limiting instrumental ADL; prescription medication indicated Grade 2 Renal Colic, CTCAE Grade 2 Renal colic 10038419 C144972 Grade 2 Renal colic Grade 2 Renal colic Moderate pain; limiting instrumental ADL; prescription medication indicated NCI Moderate pain; limiting instrumental ADL; prescription medication indicated CTCAE_v5 Grade 2 Renal Colic, CTCAE PT NCI Grade 2 Renal colic PT CTCAE_v5 ctcae5:C144974 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Reproductive System and Breast Disorders - Other, Specify, CTCAE Grade 2 Reproductive system and breast disorders - Other, specify 10038604 C144974 Grade 2 Reproductive system and breast disorders - Other, specify Grade 2 Reproductive system and breast disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Grade 2 Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C144975 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Grade 2 Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C144975 Grade 2 Respiratory, thoracic and mediastinal disorders - Other, specify Grade 2 Respiratory, thoracic and mediastinal disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Grade 2 Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C144976 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Restlessness Grade 2 Restlessness, CTCAE 10038743 C144976 Grade 2 Restlessness Grade 2 Restlessness Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Restlessness PT CTCAE_v5 Grade 2 Restlessness, CTCAE PT NCI ctcae5:C144977 No retinal detachment and treatment indicated No retinal detachment and treatment indicated Grade 2 Retinal Tear, CTCAE Grade 2 Retinal tear 10038897 C144977 Grade 2 Retinal tear Grade 2 Retinal tear No retinal detachment and treatment indicated NCI No retinal detachment and treatment indicated CTCAE_v5 Grade 2 Retinal Tear, CTCAE PT NCI Grade 2 Retinal tear PT CTCAE_v5 ctcae5:C144978 Retinal vascular disorder without neovascularization Retinal vascular disorder without neovascularization Grade 2 Retinal Vascular Disorder, CTCAE Grade 2 Retinal vascular disorder 10038901 C144978 Grade 2 Retinal vascular disorder Grade 2 Retinal vascular disorder Retinal vascular disorder without neovascularization NCI Retinal vascular disorder without neovascularization CTCAE_v5 Grade 2 Retinal Vascular Disorder, CTCAE PT NCI Grade 2 Retinal vascular disorder PT CTCAE_v5 ctcae5:C144979 Self-limited; intervention indicated Self-limited; intervention indicated Grade 2 Retroperitoneal Hemorrhage, CTCAE Grade 2 Retroperitoneal hemorrhage 10038981 C144979 Grade 2 Retroperitoneal hemorrhage Grade 2 Retroperitoneal hemorrhage Self-limited; intervention indicated NCI Self-limited; intervention indicated CTCAE_v5 Grade 2 Retroperitoneal Hemorrhage, CTCAE PT NCI Grade 2 Retroperitoneal hemorrhage PT CTCAE_v5 ctcae5:C144980 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE Grade 2 Reversible posterior leukoencephalopathy syndrome 10063761 C144980 Grade 2 Reversible posterior leukoencephalopathy syndrome Grade 2 Reversible posterior leukoencephalopathy syndrome Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE PT NCI Grade 2 Reversible posterior leukoencephalopathy syndrome PT CTCAE_v5 ctcae5:C144981 Non-urgent intervention indicated Non-urgent intervention indicated Grade 2 Rhabdomyolysis Grade 2 Rhabdomyolysis, CTCAE 10039020 C144981 Grade 2 Rhabdomyolysis Grade 2 Rhabdomyolysis Non-urgent intervention indicated NCI Non-urgent intervention indicated CTCAE_v5 Grade 2 Rhabdomyolysis PT CTCAE_v5 Grade 2 Rhabdomyolysis, CTCAE PT NCI ctcae5:C144982 Localized; local intervention indicated Localized; local intervention indicated Grade 2 Rhinitis Infective, CTCAE Grade 2 Rhinitis infective 10059827 C144982 Grade 2 Rhinitis infective Grade 2 Rhinitis infective Localized; local intervention indicated NCI Localized; local intervention indicated CTCAE_v5 Grade 2 Rhinitis Infective, CTCAE PT NCI Grade 2 Rhinitis infective PT CTCAE_v5 ctcae5:C144983 Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL Grade 2 Rotator Cuff Injury, CTCAE Grade 2 Rotator cuff injury 10039226 C144983 Grade 2 Rotator cuff injury Grade 2 Rotator cuff injury Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Rotator Cuff Injury, CTCAE PT NCI Grade 2 Rotator cuff injury PT CTCAE_v5 ctcae5:C144984 Thick, ropy, sticky saliva; markedly altered taste; alteration in diet indicated; secretion-induced symptoms; limiting instrumental ADL Thick, ropy, sticky saliva; markedly altered taste; alteration in diet indicated; secretion-induced symptoms; limiting instrumental ADL Grade 2 Salivary Duct Inflammation, CTCAE Grade 2 Salivary duct inflammation 10056681 C144984 Grade 2 Salivary duct inflammation Grade 2 Salivary duct inflammation Thick, ropy, sticky saliva; markedly altered taste; alteration in diet indicated; secretion-induced symptoms; limiting instrumental ADL NCI Thick, ropy, sticky saliva; markedly altered taste; alteration in diet indicated; secretion-induced symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Salivary Duct Inflammation, CTCAE PT NCI Grade 2 Salivary duct inflammation PT CTCAE_v5 ctcae5:C144985 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Salivary Gland Infection, CTCAE Grade 2 Salivary gland infection 10039413 C144985 Grade 2 Salivary gland infection Grade 2 Salivary gland infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Salivary Gland Infection, CTCAE PT NCI Grade 2 Salivary gland infection PT CTCAE_v5 ctcae5:C144986 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Grade 2 Scleral Disorder, CTCAE Grade 2 Scleral disorder 10061510 C144986 Grade 2 Scleral disorder Grade 2 Scleral disorder Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL CTCAE_v5 Grade 2 Scleral Disorder, CTCAE PT NCI Grade 2 Scleral disorder PT CTCAE_v5 ctcae5:C144987 >20-45 degrees; visible by forward flexion; limiting instrumental ADL >20-45 degrees; visible by forward flexion; limiting instrumental ADL Grade 2 Scoliosis Grade 2 Scoliosis, CTCAE 10039722 C144987 Grade 2 Scoliosis Grade 2 Scoliosis >20-45 degrees; visible by forward flexion; limiting instrumental ADL NCI >20-45 degrees; visible by forward flexion; limiting instrumental ADL CTCAE_v5 Grade 2 Scoliosis PT CTCAE_v5 Grade 2 Scoliosis, CTCAE PT NCI ctcae5:C144988 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Scrotal Infection, CTCAE Grade 2 Scrotal infection 10062156 C144988 Grade 2 Scrotal infection Grade 2 Scrotal infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Scrotal Infection, CTCAE PT NCI Grade 2 Scrotal infection PT CTCAE_v5 ctcae5:C144989 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Scrotal Pain, CTCAE Grade 2 Scrotal pain 10039757 C144989 Grade 2 Scrotal pain Grade 2 Scrotal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Scrotal Pain, CTCAE PT NCI Grade 2 Scrotal pain PT CTCAE_v5 ctcae5:C144990 >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic Grade 2 Serum Amylase Increased, CTCAE Grade 2 Serum amylase increased 10040139 C144990 Grade 2 Serum amylase increased Grade 2 Serum amylase increased >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic NCI >1.5-2.0 x ULN; >2.0-5.0 x ULN and asymptomatic CTCAE_v5 Grade 2 Serum Amylase Increased, CTCAE PT NCI Grade 2 Serum amylase increased PT CTCAE_v5 ctcae5:C144991 Moderate arthralgia; fever, rash, urticaria, antihistamines indicated Moderate arthralgia; fever, rash, urticaria, antihistamines indicated Grade 2 Serum Sickness, CTCAE Grade 2 Serum sickness 10040400 C144991 Grade 2 Serum sickness Grade 2 Serum sickness Moderate arthralgia; fever, rash, urticaria, antihistamines indicated NCI Moderate arthralgia; fever, rash, urticaria, antihistamines indicated CTCAE_v5 Grade 2 Serum Sickness, CTCAE PT NCI Grade 2 Serum sickness PT CTCAE_v5 ctcae5:C144992 Local infection with moderate symptoms; oral intervention indicated; limiting age-appropriate instrumental ADL Local infection with moderate symptoms; oral intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Shingles Grade 2 Shingles, CTCAE 10040555 C144992 Grade 2 Shingles Grade 2 Shingles Local infection with moderate symptoms; oral intervention indicated; limiting age-appropriate instrumental ADL NCI Local infection with moderate symptoms; oral intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Shingles PT CTCAE_v5 Grade 2 Shingles, CTCAE PT NCI ctcae5:C144993 Symptomatic stenosis or edema/narrowing interfering with airflow; limiting instrumental ADL Symptomatic stenosis or edema/narrowing interfering with airflow; limiting instrumental ADL Grade 2 Sinus Disorder, CTCAE Grade 2 Sinus disorder 10062244 C144993 Grade 2 Sinus disorder Grade 2 Sinus disorder Symptomatic stenosis or edema/narrowing interfering with airflow; limiting instrumental ADL NCI Symptomatic stenosis or edema/narrowing interfering with airflow; limiting instrumental ADL CTCAE_v5 Grade 2 Sinus Disorder, CTCAE PT NCI Grade 2 Sinus disorder PT CTCAE_v5 ctcae5:C144994 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Sinusitis Grade 2 Sinusitis, CTCAE 10040753 C144994 Grade 2 Sinusitis Grade 2 Sinusitis Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Sinusitis PT CTCAE_v5 Grade 2 Sinusitis, CTCAE PT NCI ctcae5:C144995 Blood bilirubin 2-5 mg/dL; minor interventions required (i.e., blood product, diuretic, oxygen) Blood bilirubin 2-5 mg/dL; minor interventions required (i.e., blood product, diuretic, oxygen) Grade 2 Sinusoidal Obstruction Syndrome, CTCAE Grade 2 Sinusoidal obstruction syndrome 10063675 C144995 Grade 2 Sinusoidal obstruction syndrome Grade 2 Sinusoidal obstruction syndrome Blood bilirubin 2-5 mg/dL; minor interventions required (i.e., blood product, diuretic, oxygen) NCI Blood bilirubin 2-5 mg/dL; minor interventions required (i.e., blood product, diuretic, oxygen) CTCAE_v5 Grade 2 Sinusoidal Obstruction Syndrome, CTCAE PT NCI Grade 2 Sinusoidal obstruction syndrome PT CTCAE_v5 ctcae5:C144996 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Grade 2 Skin and subcutaneous tissue disorders - Other, specify 10040785 C144996 Grade 2 Skin and subcutaneous tissue disorders - Other, specify Grade 2 Skin and subcutaneous tissue disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Grade 2 Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C144997 Hyperpigmentation covering >10% BSA; associated psychosocial impact Hyperpigmentation covering >10% BSA; associated psychosocial impact Grade 2 Skin Hyperpigmentation, CTCAE Grade 2 Skin hyperpigmentation 10040865 C144997 Grade 2 Skin hyperpigmentation Grade 2 Skin hyperpigmentation Hyperpigmentation covering >10% BSA; associated psychosocial impact NCI Hyperpigmentation covering >10% BSA; associated psychosocial impact CTCAE_v5 Grade 2 Skin Hyperpigmentation, CTCAE PT NCI Grade 2 Skin hyperpigmentation PT CTCAE_v5 ctcae5:C144998 Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact Grade 2 Skin Hypopigmentation, CTCAE Grade 2 Skin hypopigmentation 10040868 C144998 Grade 2 Skin hypopigmentation Grade 2 Skin hypopigmentation Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact NCI Hypopigmentation or depigmentation covering >10% BSA; associated psychosocial impact CTCAE_v5 Grade 2 Skin Hypopigmentation, CTCAE PT NCI Grade 2 Skin hypopigmentation PT CTCAE_v5 ctcae5:C144999 Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Grade 2 Skin Induration, CTCAE Grade 2 Skin induration 10051837 C144999 Grade 2 Skin induration Grade 2 Skin induration Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL NCI Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL CTCAE_v5 Grade 2 Skin Induration, CTCAE PT NCI Grade 2 Skin induration PT CTCAE_v5 ctcae5:C145000 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Skin Infection, CTCAE Grade 2 Skin infection 10040872 C145000 Grade 2 Skin infection Grade 2 Skin infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Skin Infection, CTCAE PT NCI Grade 2 Skin infection PT CTCAE_v5 ctcae5:C145001 Intervention initiated Intervention initiated Grade 2 Skin Papilloma, CTCAE Grade 2 Skin papilloma 10040907 C145001 Grade 2 Skin papilloma Grade 2 Skin papilloma Intervention initiated NCI Intervention initiated CTCAE_v5 Grade 2 Skin Papilloma, CTCAE PT NCI Grade 2 Skin papilloma PT CTCAE_v5 ctcae5:C145002 Combined area of ulcers 1-2 cm; partial thickness skin loss involving skin or subcutaneous fat Combined area of ulcers 1-2 cm; partial thickness skin loss involving skin or subcutaneous fat Grade 2 Skin Ulceration, CTCAE Grade 2 Skin ulceration 10040947 C145002 Grade 2 Skin ulceration Grade 2 Skin ulceration Combined area of ulcers 1-2 cm; partial thickness skin loss involving skin or subcutaneous fat NCI Combined area of ulcers 1-2 cm; partial thickness skin loss involving skin or subcutaneous fat CTCAE_v5 Grade 2 Skin Ulceration, CTCAE PT NCI Grade 2 Skin ulceration PT CTCAE_v5 ctcae5:C145003 Moderate apnea and oxygen desaturation; excessive daytime sleepiness; medical evaluation indicated; limiting instrumental ADL Moderate apnea and oxygen desaturation; excessive daytime sleepiness; medical evaluation indicated; limiting instrumental ADL Grade 2 Sleep Apnea, CTCAE Grade 2 Sleep apnea 10040975 C145003 Grade 2 Sleep apnea Grade 2 Sleep apnea Moderate apnea and oxygen desaturation; excessive daytime sleepiness; medical evaluation indicated; limiting instrumental ADL NCI Moderate apnea and oxygen desaturation; excessive daytime sleepiness; medical evaluation indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Sleep Apnea, CTCAE PT NCI Grade 2 Sleep apnea PT CTCAE_v5 ctcae5:C145004 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Small Intestinal Anastomotic Leak, CTCAE Grade 2 Small intestinal anastomotic leak 10065892 C145004 Grade 2 Small intestinal anastomotic leak Grade 2 Small intestinal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Small Intestinal Anastomotic Leak, CTCAE PT NCI Grade 2 Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C145005 Symptomatic; medical intervention indicated; limiting instrumental ADL Symptomatic; medical intervention indicated; limiting instrumental ADL Grade 2 Small Intestinal Mucositis, CTCAE Grade 2 Small intestinal mucositis 10065710 C145005 Grade 2 Small intestinal mucositis Grade 2 Small intestinal mucositis Symptomatic; medical intervention indicated; limiting instrumental ADL NCI Symptomatic; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Small Intestinal Mucositis, CTCAE PT NCI Grade 2 Small intestinal mucositis PT CTCAE_v5 ctcae5:C145006 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Small Intestinal Obstruction, CTCAE Grade 2 Small intestinal obstruction 10041101 C145006 Grade 2 Small intestinal obstruction Grade 2 Small intestinal obstruction Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Small Intestinal Obstruction, CTCAE PT NCI Grade 2 Small intestinal obstruction PT CTCAE_v5 ctcae5:C145007 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Small Intestinal Perforation, CTCAE Grade 2 Small intestinal perforation 10041103 C145007 Grade 2 Small intestinal perforation Grade 2 Small intestinal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Small Intestinal Perforation, CTCAE PT NCI Grade 2 Small intestinal perforation PT CTCAE_v5 ctcae5:C145008 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Small Intestinal Stenosis, CTCAE Grade 2 Small intestinal stenosis 10062263 C145008 Grade 2 Small intestinal stenosis Grade 2 Small intestinal stenosis Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Small Intestinal Stenosis, CTCAE PT NCI Grade 2 Small intestinal stenosis PT CTCAE_v5 ctcae5:C145009 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Small Intestine Infection, CTCAE Grade 2 Small intestine infection 10065771 C145009 Grade 2 Small intestine infection Grade 2 Small intestine infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Small Intestine Infection, CTCAE PT NCI Grade 2 Small intestine infection PT CTCAE_v5 ctcae5:C145010 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Small Intestine Ulcer, CTCAE Grade 2 Small intestine ulcer 10041133 C145010 Grade 2 Small intestine ulcer Grade 2 Small intestine ulcer Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Small Intestine Ulcer, CTCAE PT NCI Grade 2 Small intestine ulcer PT CTCAE_v5 ctcae5:C145011 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Sneezing Grade 2 Sneezing, CTCAE 10041232 C145011 Grade 2 Sneezing Grade 2 Sneezing Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Sneezing PT CTCAE_v5 Grade 2 Sneezing, CTCAE PT NCI ctcae5:C145012 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Social Circumstances - Other, Specify, CTCAE Grade 2 Social circumstances - Other, specify 10041244 C145012 Grade 2 Social circumstances - Other, specify Grade 2 Social circumstances - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Social Circumstances - Other, Specify, CTCAE PT NCI Grade 2 Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C145013 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Soft Tissue Infection, CTCAE Grade 2 Soft tissue infection 10062255 C145013 Grade 2 Soft tissue infection Grade 2 Soft tissue infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Soft Tissue Infection, CTCAE PT NCI Grade 2 Soft tissue infection PT CTCAE_v5 ctcae5:C145014 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Soft Tissue Necrosis Lower Limb, CTCAE Grade 2 Soft tissue necrosis lower limb 10065777 C145014 Grade 2 Soft tissue necrosis lower limb Grade 2 Soft tissue necrosis lower limb Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Soft Tissue Necrosis Lower Limb, CTCAE PT NCI Grade 2 Soft tissue necrosis lower limb PT CTCAE_v5 ctcae5:C145015 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Soft Tissue Necrosis Upper Limb, CTCAE Grade 2 Soft tissue necrosis upper limb 10065778 C145015 Grade 2 Soft tissue necrosis upper limb Grade 2 Soft tissue necrosis upper limb Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Soft Tissue Necrosis Upper Limb, CTCAE PT NCI Grade 2 Soft tissue necrosis upper limb PT CTCAE_v5 ctcae5:C145016 Moderate sedation; limiting instrumental ADL Moderate sedation; limiting instrumental ADL Grade 2 Somnolence Grade 2 Somnolence, CTCAE 10041349 C145016 Grade 2 Somnolence Grade 2 Somnolence Moderate sedation; limiting instrumental ADL NCI Moderate sedation; limiting instrumental ADL CTCAE_v5 Grade 2 Somnolence PT CTCAE_v5 Grade 2 Somnolence, CTCAE PT NCI ctcae5:C145017 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Sore Throat, CTCAE Grade 2 Sore throat 10041367 C145017 Grade 2 Sore throat Grade 2 Sore throat Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Sore Throat, CTCAE PT NCI Grade 2 Sore throat PT CTCAE_v5 ctcae5:C145018 Moderate increase in muscle tone and increase in resistance through range of motion Moderate increase in muscle tone and increase in resistance through range of motion Grade 2 Spasticity Grade 2 Spasticity, CTCAE 10041416 C145018 Grade 2 Spasticity Grade 2 Spasticity Moderate increase in muscle tone and increase in resistance through range of motion NCI Moderate increase in muscle tone and increase in resistance through range of motion CTCAE_v5 Grade 2 Spasticity PT CTCAE_v5 Grade 2 Spasticity, CTCAE PT NCI ctcae5:C145019 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Spermatic Cord Anastomotic Leak, CTCAE Grade 2 Spermatic cord anastomotic leak 10065897 C145019 Grade 2 Spermatic cord anastomotic leak Grade 2 Spermatic cord anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Grade 2 Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C145020 Moderate back pain; prescription analgesics indicated; limiting instrumental ADL Moderate back pain; prescription analgesics indicated; limiting instrumental ADL Grade 2 Spinal Fracture, CTCAE Grade 2 Spinal fracture 10041569 C145020 Grade 2 Spinal fracture Grade 2 Spinal fracture Moderate back pain; prescription analgesics indicated; limiting instrumental ADL NCI Moderate back pain; prescription analgesics indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Spinal Fracture, CTCAE PT NCI Grade 2 Spinal fracture PT CTCAE_v5 ctcae5:C145021 Symptomatic; IV fluids indicated <24 hrs; manual dilation at bedside Symptomatic; IV fluids indicated <24 hrs; manual dilation at bedside Grade 2 Stenosis of Gastrointestinal Stoma, CTCAE Grade 2 Stenosis of gastrointestinal stoma 10065898 C145021 Grade 2 Stenosis of gastrointestinal stoma Grade 2 Stenosis of gastrointestinal stoma Symptomatic; IV fluids indicated <24 hrs; manual dilation at bedside NCI Symptomatic; IV fluids indicated <24 hrs; manual dilation at bedside CTCAE_v5 Grade 2 Stenosis of Gastrointestinal Stoma, CTCAE PT NCI Grade 2 Stenosis of gastrointestinal stoma PT CTCAE_v5 ctcae5:C145022 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Stoma Site Infection, CTCAE Grade 2 Stoma site infection 10064505 C145022 Grade 2 Stoma site infection Grade 2 Stoma site infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Stoma Site Infection, CTCAE PT NCI Grade 2 Stoma site infection PT CTCAE_v5 ctcae5:C145023 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Stomal Ulcer, CTCAE Grade 2 Stomal ulcer 10042127 C145023 Grade 2 Stomal ulcer Grade 2 Stomal ulcer Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Stomal Ulcer, CTCAE PT NCI Grade 2 Stomal ulcer PT CTCAE_v5 ctcae5:C145024 Mild to moderate neurologic deficit; limiting instrumental ADL Mild to moderate neurologic deficit; limiting instrumental ADL Grade 2 Stroke Grade 2 Stroke, CTCAE 10042244 C145024 Grade 2 Stroke Grade 2 Stroke Mild to moderate neurologic deficit; limiting instrumental ADL NCI Mild to moderate neurologic deficit; limiting instrumental ADL CTCAE_v5 Grade 2 Stroke PT CTCAE_v5 Grade 2 Stroke, CTCAE PT NCI ctcae5:C145025 Moderate; minimal, local or noninvasive intervention indicated Moderate; minimal, local or noninvasive intervention indicated Grade 2 Subcutaneous Emphysema, CTCAE Grade 2 Subcutaneous emphysema 10042344 C145025 Grade 2 Subcutaneous emphysema Grade 2 Subcutaneous emphysema Moderate; minimal, local or noninvasive intervention indicated NCI Moderate; minimal, local or noninvasive intervention indicated CTCAE_v5 Grade 2 Subcutaneous Emphysema, CTCAE PT NCI Grade 2 Subcutaneous emphysema PT CTCAE_v5 ctcae5:C145026 Suicidal ideation with no specific plan or intent Suicidal ideation with no specific plan or intent Grade 2 Suicidal Ideation, CTCAE Grade 2 Suicidal ideation 10042458 C145026 Grade 2 Suicidal ideation Grade 2 Suicidal ideation Suicidal ideation with no specific plan or intent NCI Suicidal ideation with no specific plan or intent CTCAE_v5 Grade 2 Suicidal Ideation, CTCAE PT NCI Grade 2 Suicidal ideation PT CTCAE_v5 ctcae5:C145027 Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL Grade 2 Superficial Soft Tissue Fibrosis, CTCAE Grade 2 Superficial soft tissue fibrosis 10065798 C145027 Grade 2 Superficial soft tissue fibrosis Grade 2 Superficial soft tissue fibrosis Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL NCI Moderate induration, able to slide skin, unable to pinch skin; limiting instrumental ADL CTCAE_v5 Grade 2 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Grade 2 Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C145028 Present Present Grade 2 Superficial Thrombophlebitis, CTCAE Grade 2 Superficial thrombophlebitis 10042554 C145028 Grade 2 Superficial thrombophlebitis Grade 2 Superficial thrombophlebitis Present NCI Present CTCAE_v5 Grade 2 Superficial Thrombophlebitis, CTCAE PT NCI Grade 2 Superficial thrombophlebitis PT CTCAE_v5 ctcae5:C145029 Symptomatic; medical intervention indicated (e.g., anticoagulation, radiation or chemotherapy) Symptomatic; medical intervention indicated (e.g., anticoagulation, radiation or chemotherapy) Grade 2 Superior Vena Cava Syndrome, CTCAE Grade 2 Superior vena cava syndrome 10042569 C145029 Grade 2 Superior vena cava syndrome Grade 2 Superior vena cava syndrome Symptomatic; medical intervention indicated (e.g., anticoagulation, radiation or chemotherapy) NCI Symptomatic; medical intervention indicated (e.g., anticoagulation, radiation or chemotherapy) CTCAE_v5 Grade 2 Superior Vena Cava Syndrome, CTCAE PT NCI Grade 2 Superior vena cava syndrome PT CTCAE_v5 ctcae5:C145030 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Surgical and Medical Procedures - Other, Specify, CTCAE Grade 2 Surgical and medical procedures - Other, specify 10042613 C145030 Grade 2 Surgical and medical procedures - Other, specify Grade 2 Surgical and medical procedures - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Grade 2 Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C145031 Ankle reflex absent; other reflexes reduced Ankle reflex absent; other reflexes reduced Grade 2 Tendon Reflex Decreased, CTCAE Grade 2 Tendon reflex decreased 10043245 C145031 Grade 2 Tendon reflex decreased Grade 2 Tendon reflex decreased Ankle reflex absent; other reflexes reduced NCI Ankle reflex absent; other reflexes reduced CTCAE_v5 Grade 2 Tendon Reflex Decreased, CTCAE PT NCI Grade 2 Tendon reflex decreased PT CTCAE_v5 ctcae5:C145032 Symptomatic but not interfering with sexual function; intervention not indicated; limiting instrumental ADL Symptomatic but not interfering with sexual function; intervention not indicated; limiting instrumental ADL Grade 2 Testicular Disorder, CTCAE Grade 2 Testicular disorder 10043306 C145032 Grade 2 Testicular disorder Grade 2 Testicular disorder Symptomatic but not interfering with sexual function; intervention not indicated; limiting instrumental ADL NCI Symptomatic but not interfering with sexual function; intervention not indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Testicular Disorder, CTCAE PT NCI Grade 2 Testicular disorder PT CTCAE_v5 ctcae5:C145034 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Testicular Pain, CTCAE Grade 2 Testicular pain 10043345 C145034 Grade 2 Testicular pain Grade 2 Testicular pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Testicular Pain, CTCAE PT NCI Grade 2 Testicular pain PT CTCAE_v5 ctcae5:C145035 Replacement therapy initiated Replacement therapy initiated Grade 2 Testosterone Deficiency, CTCAE Grade 2 Testosterone deficiency 10067734 C145035 Grade 2 Testosterone deficiency Grade 2 Testosterone deficiency Replacement therapy initiated NCI Replacement therapy initiated CTCAE_v5 Grade 2 Testosterone Deficiency, CTCAE PT NCI Grade 2 Testosterone deficiency PT CTCAE_v5 ctcae5:C145036 Medical intervention indicated Medical intervention indicated Grade 2 Thromboembolic Event, CTCAE Grade 2 Thromboembolic event 10043565 C145036 Grade 2 Thromboembolic event Grade 2 Thromboembolic event Medical intervention indicated NCI Medical intervention indicated CTCAE_v5 Grade 2 Thromboembolic Event, CTCAE PT NCI Grade 2 Thromboembolic event PT CTCAE_v5 ctcae5:C145037 Oral intervention indicated (e.g., antifungal) Oral intervention indicated (e.g., antifungal) Grade 2 Thrush Grade 2 Thrush, CTCAE 10043649 C145037 Grade 2 Thrush Grade 2 Thrush Oral intervention indicated (e.g., antifungal) NCI Oral intervention indicated (e.g., antifungal) CTCAE_v5 Grade 2 Thrush PT CTCAE_v5 Grade 2 Thrush, CTCAE PT NCI ctcae5:C145038 Impairment correctable with oral surgery Impairment correctable with oral surgery Grade 2 Tooth Development Disorder, CTCAE Grade 2 Tooth development disorder 10044030 C145038 Grade 2 Tooth development disorder Grade 2 Tooth development disorder Impairment correctable with oral surgery NCI Impairment correctable with oral surgery CTCAE_v5 Grade 2 Tooth Development Disorder, CTCAE PT NCI Grade 2 Tooth development disorder PT CTCAE_v5 ctcae5:C145039 Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) Grade 2 Tooth Infection, CTCAE Grade 2 Tooth infection 10048762 C145039 Grade 2 Tooth infection Grade 2 Tooth infection Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) NCI Localized; local intervention indicated (e.g., topical antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Tooth Infection, CTCAE PT NCI Grade 2 Tooth infection PT CTCAE_v5 ctcae5:C145040 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Toothache Grade 2 Toothache, CTCAE 10044055 C145040 Grade 2 Toothache Grade 2 Toothache Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Toothache PT CTCAE_v5 Grade 2 Toothache, CTCAE PT NCI ctcae5:C145043 Moderate symptoms; medical intervention indicated; limiting instrumental ADL Moderate symptoms; medical intervention indicated; limiting instrumental ADL Grade 2 Tracheal Mucositis, CTCAE Grade 2 Tracheal mucositis 10065900 C145043 Grade 2 Tracheal mucositis Grade 2 Tracheal mucositis Moderate symptoms; medical intervention indicated; limiting instrumental ADL NCI Moderate symptoms; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Tracheal Mucositis, CTCAE PT NCI Grade 2 Tracheal mucositis PT CTCAE_v5 ctcae5:C145044 Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Grade 2 Tracheal Obstruction, CTCAE Grade 2 Tracheal obstruction 10044291 C145044 Grade 2 Tracheal obstruction Grade 2 Tracheal obstruction Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL NCI Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL CTCAE_v5 Grade 2 Tracheal Obstruction, CTCAE PT NCI Grade 2 Tracheal obstruction PT CTCAE_v5 ctcae5:C145045 Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL Grade 2 Tracheal Stenosis, CTCAE Grade 2 Tracheal stenosis 10050816 C145045 Grade 2 Tracheal stenosis Grade 2 Tracheal stenosis Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL NCI Symptomatic (e.g., noisy airway breathing), no respiratory distress; medical intervention indicated (e.g., steroids); limiting instrumental ADL CTCAE_v5 Grade 2 Tracheal Stenosis, CTCAE PT NCI Grade 2 Tracheal stenosis PT CTCAE_v5 ctcae5:C145046 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Tracheitis Grade 2 Tracheitis, CTCAE 10044302 C145046 Grade 2 Tracheitis Grade 2 Tracheitis Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Tracheitis PT CTCAE_v5 Grade 2 Tracheitis, CTCAE PT NCI ctcae5:C145047 Moderate bleeding; medical intervention indicated Moderate bleeding; medical intervention indicated Grade 2 Tracheostomy Site Bleeding, CTCAE Grade 2 Tracheostomy site bleeding 10065749 C145047 Grade 2 Tracheostomy site bleeding Grade 2 Tracheostomy site bleeding Moderate bleeding; medical intervention indicated NCI Moderate bleeding; medical intervention indicated CTCAE_v5 Grade 2 Tracheostomy Site Bleeding, CTCAE PT NCI Grade 2 Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C145048 Moderate neurologic deficit with or without imaging confirmation Moderate neurologic deficit with or without imaging confirmation Grade 2 Transient Ischemic Attacks, CTCAE Grade 2 Transient ischemic attacks 10044391 C145048 Grade 2 Transient ischemic attacks Grade 2 Transient ischemic attacks Moderate neurologic deficit with or without imaging confirmation NCI Moderate neurologic deficit with or without imaging confirmation CTCAE_v5 Grade 2 Transient Ischemic Attacks, CTCAE PT NCI Grade 2 Transient ischemic attacks PT CTCAE_v5 ctcae5:C145049 Asymptomatic; moderate regurgitation or stenosis by imaging Asymptomatic; moderate regurgitation or stenosis by imaging Grade 2 Tricuspid Valve Disease, CTCAE Grade 2 Tricuspid valve disease 10061389 C145049 Grade 2 Tricuspid valve disease Grade 2 Tricuspid valve disease Asymptomatic; moderate regurgitation or stenosis by imaging NCI Asymptomatic; moderate regurgitation or stenosis by imaging CTCAE_v5 Grade 2 Tricuspid Valve Disease, CTCAE PT NCI Grade 2 Tricuspid valve disease PT CTCAE_v5 ctcae5:C145050 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Trigeminal Nerve Disorder, CTCAE Grade 2 Trigeminal nerve disorder 10060890 C145050 Grade 2 Trigeminal nerve disorder Grade 2 Trigeminal nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Trigeminal Nerve Disorder, CTCAE PT NCI Grade 2 Trigeminal nerve disorder PT CTCAE_v5 ctcae5:C145051 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Trochlear Nerve Disorder, CTCAE Grade 2 Trochlear nerve disorder 10074765 C145051 Grade 2 Trochlear nerve disorder Grade 2 Trochlear nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Trochlear Nerve Disorder, CTCAE PT NCI Grade 2 Trochlear nerve disorder PT CTCAE_v5 ctcae5:C145052 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Tumor Hemorrhage, CTCAE Grade 2 Tumor hemorrhage 10055351 C145052 Grade 2 Tumor hemorrhage Grade 2 Tumor hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Tumor Hemorrhage, CTCAE PT NCI Grade 2 Tumor hemorrhage PT CTCAE_v5 ctcae5:C145053 Moderate length discrepancy 2-5 cm; shoe lift indicated; limiting instrumental ADL Moderate length discrepancy 2-5 cm; shoe lift indicated; limiting instrumental ADL Grade 2 Unequal Limb Length, CTCAE Grade 2 Unequal limb length 10065738 C145053 Grade 2 Unequal limb length Grade 2 Unequal limb length Moderate length discrepancy 2-5 cm; shoe lift indicated; limiting instrumental ADL NCI Moderate length discrepancy 2-5 cm; shoe lift indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Unequal Limb Length, CTCAE PT NCI Grade 2 Unequal limb length PT CTCAE_v5 ctcae5:C145054 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Upper Gastrointestinal Hemorrhage, CTCAE Grade 2 Upper gastrointestinal hemorrhage 10055356 C145054 Grade 2 Upper gastrointestinal hemorrhage Grade 2 Upper gastrointestinal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 2 Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C145055 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Upper Respiratory Infection, CTCAE Grade 2 Upper respiratory infection 10046300 C145055 Grade 2 Upper respiratory infection Grade 2 Upper respiratory infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Upper Respiratory Infection, CTCAE PT NCI Grade 2 Upper respiratory infection PT CTCAE_v5 ctcae5:C145056 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Ureteric Anastomotic Leak, CTCAE Grade 2 Ureteric anastomotic leak 10065814 C145056 Grade 2 Ureteric anastomotic leak Grade 2 Ureteric anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Ureteric Anastomotic Leak, CTCAE PT NCI Grade 2 Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C145057 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Urethral Anastomotic Leak, CTCAE Grade 2 Urethral anastomotic leak 10065815 C145057 Grade 2 Urethral anastomotic leak Grade 2 Urethral anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Urethral Anastomotic Leak, CTCAE PT NCI Grade 2 Urethral anastomotic leak PT CTCAE_v5 ctcae5:C145058 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Urethral Infection, CTCAE Grade 2 Urethral infection 10052298 C145058 Grade 2 Urethral infection Grade 2 Urethral infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Urethral Infection, CTCAE PT NCI Grade 2 Urethral infection PT CTCAE_v5 ctcae5:C145059 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Urinary Fistula, CTCAE Grade 2 Urinary fistula 10065368 C145059 Grade 2 Urinary fistula Grade 2 Urinary fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Urinary Fistula, CTCAE PT NCI Grade 2 Urinary fistula PT CTCAE_v5 ctcae5:C145060 Limiting instrumental ADL; medical management indicated Limiting instrumental ADL; medical management indicated Grade 2 Urinary Frequency, CTCAE Grade 2 Urinary frequency 10046539 C145060 Grade 2 Urinary frequency Grade 2 Urinary frequency Limiting instrumental ADL; medical management indicated NCI Limiting instrumental ADL; medical management indicated CTCAE_v5 Grade 2 Urinary Frequency, CTCAE PT NCI Grade 2 Urinary frequency PT CTCAE_v5 ctcae5:C145061 Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Urinary Tract Infection, CTCAE Grade 2 Urinary tract infection 10046571 C145061 Grade 2 Urinary tract infection Grade 2 Urinary tract infection Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Localized; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Urinary Tract Infection, CTCAE PT NCI Grade 2 Urinary tract infection PT CTCAE_v5 ctcae5:C145062 Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; urethral dilation, urinary or suprapubic catheter indicated Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; urethral dilation, urinary or suprapubic catheter indicated Grade 2 Urinary Tract Obstruction, CTCAE Grade 2 Urinary tract obstruction 10061574 C145062 Grade 2 Urinary tract obstruction Grade 2 Urinary tract obstruction Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; urethral dilation, urinary or suprapubic catheter indicated NCI Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; urethral dilation, urinary or suprapubic catheter indicated CTCAE_v5 Grade 2 Urinary Tract Obstruction, CTCAE PT NCI Grade 2 Urinary tract obstruction PT CTCAE_v5 ctcae5:C145063 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Urinary Tract Pain, CTCAE Grade 2 Urinary tract pain 10062225 C145063 Grade 2 Urinary tract pain Grade 2 Urinary tract pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Urinary Tract Pain, CTCAE PT NCI Grade 2 Urinary tract pain PT CTCAE_v5 ctcae5:C145064 Limiting instrumental ADL; medical management indicated Limiting instrumental ADL; medical management indicated Grade 2 Urinary Urgency, CTCAE Grade 2 Urinary urgency 10046593 C145064 Grade 2 Urinary urgency Grade 2 Urinary urgency Limiting instrumental ADL; medical management indicated NCI Limiting instrumental ADL; medical management indicated CTCAE_v5 Grade 2 Urinary Urgency, CTCAE PT NCI Grade 2 Urinary urgency PT CTCAE_v5 ctcae5:C145065 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Urostomy Leak, CTCAE Grade 2 Urostomy leak 10065882 C145065 Grade 2 Urostomy leak Grade 2 Urostomy leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Urostomy Leak, CTCAE PT NCI Grade 2 Urostomy leak PT CTCAE_v5 ctcae5:C145066 Symptomatic; dilation or endoscopic repair or stent placement indicated Symptomatic; dilation or endoscopic repair or stent placement indicated Grade 2 Urostomy Obstruction, CTCAE Grade 2 Urostomy obstruction 10065883 C145066 Grade 2 Urostomy obstruction Grade 2 Urostomy obstruction Symptomatic; dilation or endoscopic repair or stent placement indicated NCI Symptomatic; dilation or endoscopic repair or stent placement indicated CTCAE_v5 Grade 2 Urostomy Obstruction, CTCAE PT NCI Grade 2 Urostomy obstruction PT CTCAE_v5 ctcae5:C145067 Moderate bleeding; medical intervention indicated Moderate bleeding; medical intervention indicated Grade 2 Urostomy Site Bleeding, CTCAE Grade 2 Urostomy site bleeding 10065748 C145067 Grade 2 Urostomy site bleeding Grade 2 Urostomy site bleeding Moderate bleeding; medical intervention indicated NCI Moderate bleeding; medical intervention indicated CTCAE_v5 Grade 2 Urostomy Site Bleeding, CTCAE PT NCI Grade 2 Urostomy site bleeding PT CTCAE_v5 ctcae5:C145068 Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; dilation or endoscopic repair or stent placement indicated Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; dilation or endoscopic repair or stent placement indicated Grade 2 Urostomy Stenosis, CTCAE Grade 2 Urostomy stenosis 10065885 C145068 Grade 2 Urostomy stenosis Grade 2 Urostomy stenosis Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; dilation or endoscopic repair or stent placement indicated NCI Symptomatic but no hydronephrosis, sepsis, or renal dysfunction; dilation or endoscopic repair or stent placement indicated CTCAE_v5 Grade 2 Urostomy Stenosis, CTCAE PT NCI Grade 2 Urostomy stenosis PT CTCAE_v5 ctcae5:C145069 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Uterine Anastomotic Leak, CTCAE Grade 2 Uterine anastomotic leak 10065886 C145069 Grade 2 Uterine anastomotic leak Grade 2 Uterine anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Uterine Anastomotic Leak, CTCAE PT NCI Grade 2 Uterine anastomotic leak PT CTCAE_v5 ctcae5:C145070 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Uterine Fistula, CTCAE Grade 2 Uterine fistula 10065811 C145070 Grade 2 Uterine fistula Grade 2 Uterine fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Uterine Fistula, CTCAE PT NCI Grade 2 Uterine fistula PT CTCAE_v5 ctcae5:C145072 Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Uterine Infection, CTCAE Grade 2 Uterine infection 10062233 C145072 Grade 2 Uterine infection Grade 2 Uterine infection Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Moderate symptoms; oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Uterine Infection, CTCAE PT NCI Grade 2 Uterine infection PT CTCAE_v5 ctcae5:C145073 Symptomatic; elective intervention indicated Symptomatic; elective intervention indicated Grade 2 Uterine Obstruction, CTCAE Grade 2 Uterine obstruction 10065928 C145073 Grade 2 Uterine obstruction Grade 2 Uterine obstruction Symptomatic; elective intervention indicated NCI Symptomatic; elective intervention indicated CTCAE_v5 Grade 2 Uterine Obstruction, CTCAE PT NCI Grade 2 Uterine obstruction PT CTCAE_v5 ctcae5:C145074 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Uterine Pain, CTCAE Grade 2 Uterine pain 10046809 C145074 Grade 2 Uterine pain Grade 2 Uterine pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Uterine Pain, CTCAE PT NCI Grade 2 Uterine pain PT CTCAE_v5 ctcae5:C145075 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Uterine Perforation, CTCAE Grade 2 Uterine perforation 10046810 C145075 Grade 2 Uterine perforation Grade 2 Uterine perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Uterine Perforation, CTCAE PT NCI Grade 2 Uterine perforation PT CTCAE_v5 ctcae5:C145076 Moderate pain; Erythema 5.1-10 cm; Induration/swelling 5.1-10 cm; lipodystrophy; limiting instrumental ADL Moderate pain; Erythema 5.1-10 cm; Induration/swelling 5.1-10 cm; lipodystrophy; limiting instrumental ADL Grade 2 Vaccination Complication, CTCAE Grade 2 Vaccination complication 10046861 C145076 Grade 2 Vaccination complication Grade 2 Vaccination complication Moderate pain; Erythema 5.1-10 cm; Induration/swelling 5.1-10 cm; lipodystrophy; limiting instrumental ADL NCI Moderate pain; Erythema 5.1-10 cm; Induration/swelling 5.1-10 cm; lipodystrophy; limiting instrumental ADL CTCAE_v5 Grade 2 Vaccination Complication, CTCAE PT NCI Grade 2 Vaccination complication PT CTCAE_v5 ctcae5:C145077 Localized ulceration; generalized lymph node enlargement Localized ulceration; generalized lymph node enlargement Grade 2 Vaccination Site Lymphadenopathy, CTCAE Grade 2 Vaccination site lymphadenopathy 10069480 C145077 Grade 2 Vaccination site lymphadenopathy Grade 2 Vaccination site lymphadenopathy Localized ulceration; generalized lymph node enlargement NCI Localized ulceration; generalized lymph node enlargement CTCAE_v5 Grade 2 Vaccination Site Lymphadenopathy, CTCAE PT NCI Grade 2 Vaccination site lymphadenopathy PT CTCAE_v5 ctcae5:C145078 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Vaginal Anastomotic Leak, CTCAE Grade 2 Vaginal anastomotic leak 10065887 C145078 Grade 2 Vaginal anastomotic leak Grade 2 Vaginal anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Vaginal Anastomotic Leak, CTCAE PT NCI Grade 2 Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C145079 Moderate to heavy vaginal discharge; use of perineal pad or tampon indicated Moderate to heavy vaginal discharge; use of perineal pad or tampon indicated Grade 2 Vaginal Discharge, CTCAE Grade 2 Vaginal discharge 10046901 C145079 Grade 2 Vaginal discharge Grade 2 Vaginal discharge Moderate to heavy vaginal discharge; use of perineal pad or tampon indicated NCI Moderate to heavy vaginal discharge; use of perineal pad or tampon indicated CTCAE_v5 Grade 2 Vaginal Discharge, CTCAE PT NCI Grade 2 Vaginal discharge PT CTCAE_v5 ctcae5:C145082 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Vaginal Infection, CTCAE Grade 2 Vaginal infection 10046914 C145082 Grade 2 Vaginal infection Grade 2 Vaginal infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Vaginal Infection, CTCAE PT NCI Grade 2 Vaginal infection PT CTCAE_v5 ctcae5:C145083 Moderate discomfort or pain, edema, or redness; limiting instrumental ADL Moderate discomfort or pain, edema, or redness; limiting instrumental ADL Grade 2 Vaginal Inflammation, CTCAE Grade 2 Vaginal inflammation 10046916 C145083 Grade 2 Vaginal inflammation Grade 2 Vaginal inflammation Moderate discomfort or pain, edema, or redness; limiting instrumental ADL NCI Moderate discomfort or pain, edema, or redness; limiting instrumental ADL CTCAE_v5 Grade 2 Vaginal Inflammation, CTCAE PT NCI Grade 2 Vaginal inflammation PT CTCAE_v5 ctcae5:C145084 Symptomatic; elective intervention indicated Symptomatic; elective intervention indicated Grade 2 Vaginal Obstruction, CTCAE Grade 2 Vaginal obstruction 10065817 C145084 Grade 2 Vaginal obstruction Grade 2 Vaginal obstruction Symptomatic; elective intervention indicated NCI Symptomatic; elective intervention indicated CTCAE_v5 Grade 2 Vaginal Obstruction, CTCAE PT NCI Grade 2 Vaginal obstruction PT CTCAE_v5 ctcae5:C145085 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Vaginal Pain, CTCAE Grade 2 Vaginal pain 10046937 C145085 Grade 2 Vaginal pain Grade 2 Vaginal pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Vaginal Pain, CTCAE PT NCI Grade 2 Vaginal pain PT CTCAE_v5 ctcae5:C145086 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Vaginal Perforation, CTCAE Grade 2 Vaginal perforation 10065818 C145086 Grade 2 Vaginal perforation Grade 2 Vaginal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Vaginal Perforation, CTCAE PT NCI Grade 2 Vaginal perforation PT CTCAE_v5 ctcae5:C145087 Vaginal narrowing and/or shortening not interfering with physical examination Vaginal narrowing and/or shortening not interfering with physical examination Grade 2 Vaginal Stricture, CTCAE Grade 2 Vaginal stricture 10053496 C145087 Grade 2 Vaginal stricture Grade 2 Vaginal stricture Vaginal narrowing and/or shortening not interfering with physical examination NCI Vaginal narrowing and/or shortening not interfering with physical examination CTCAE_v5 Grade 2 Vaginal Stricture, CTCAE PT NCI Grade 2 Vaginal stricture PT CTCAE_v5 ctcae5:C145088 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Vagus Nerve Disorder, CTCAE Grade 2 Vagus nerve disorder 10061403 C145088 Grade 2 Vagus nerve disorder Grade 2 Vagus nerve disorder Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Vagus Nerve Disorder, CTCAE PT NCI Grade 2 Vagus nerve disorder PT CTCAE_v5 ctcae5:C145089 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Vas Deferens Anastomotic Leak, CTCAE Grade 2 Vas deferens anastomotic leak 10065888 C145089 Grade 2 Vas deferens anastomotic leak Grade 2 Vas deferens anastomotic leak Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Vas Deferens Anastomotic Leak, CTCAE PT NCI Grade 2 Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C145090 Device dislodgement, blockage, leak, or malposition; device replacement indicated Device dislodgement, blockage, leak, or malposition; device replacement indicated Grade 2 Vascular Access Complication, CTCAE Grade 2 Vascular access complication 10062169 C145090 Grade 2 Vascular access complication Grade 2 Vascular access complication Device dislodgement, blockage, leak, or malposition; device replacement indicated NCI Device dislodgement, blockage, leak, or malposition; device replacement indicated CTCAE_v5 Grade 2 Vascular Access Complication, CTCAE PT NCI Grade 2 Vascular access complication PT CTCAE_v5 ctcae5:C145091 Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Grade 2 Vascular Disorders - Other, Specify, CTCAE Grade 2 Vascular disorders - Other, specify 10047065 C145091 Grade 2 Vascular disorders - Other, specify Grade 2 Vascular disorders - Other, specify Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL NCI Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL CTCAE_v5 Grade 2 Vascular Disorders - Other, Specify, CTCAE PT NCI Grade 2 Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C145092 Symptomatic (e.g., claudication); repair or revision not indicated Symptomatic (e.g., claudication); repair or revision not indicated Grade 2 Venous Injury, CTCAE Grade 2 Venous injury 10047228 C145092 Grade 2 Venous injury Grade 2 Venous injury Symptomatic (e.g., claudication); repair or revision not indicated NCI Symptomatic (e.g., claudication); repair or revision not indicated CTCAE_v5 Grade 2 Venous Injury, CTCAE PT NCI Grade 2 Venous injury PT CTCAE_v5 ctcae5:C145093 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Ventricular Arrhythmia, CTCAE Grade 2 Ventricular arrhythmia 10047281 C145093 Grade 2 Ventricular arrhythmia Grade 2 Ventricular arrhythmia Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Ventricular Arrhythmia, CTCAE PT NCI Grade 2 Ventricular arrhythmia PT CTCAE_v5 ctcae5:C145094 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Vertigo Grade 2 Vertigo, CTCAE 10047340 C145094 Grade 2 Vertigo Grade 2 Vertigo Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Vertigo PT CTCAE_v5 Grade 2 Vertigo, CTCAE PT NCI ctcae5:C145095 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Vestibular Disorder, CTCAE Grade 2 Vestibular disorder 10047386 C145095 Grade 2 Vestibular disorder Grade 2 Vestibular disorder Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Vestibular Disorder, CTCAE PT NCI Grade 2 Vestibular disorder PT CTCAE_v5 ctcae5:C145096 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Viremia Grade 2 Viremia, CTCAE 10054688 C145096 Grade 2 Viremia Grade 2 Viremia Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Viremia PT CTCAE_v5 Grade 2 Viremia, CTCAE PT NCI ctcae5:C145097 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Virilization Grade 2 Virilization, CTCAE 10047488 C145097 Grade 2 Virilization Grade 2 Virilization Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Virilization PT CTCAE_v5 Grade 2 Virilization, CTCAE PT NCI ctcae5:C145098 Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit Grade 2 Visceral Arterial Ischemia, CTCAE Grade 2 Visceral arterial ischemia 10054692 C145098 Grade 2 Visceral arterial ischemia Grade 2 Visceral arterial ischemia Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit NCI Brief (<24 hrs) episode of ischemia managed medically and without permanent deficit CTCAE_v5 Grade 2 Visceral Arterial Ischemia, CTCAE PT NCI Grade 2 Visceral arterial ischemia PT CTCAE_v5 ctcae5:C145099 Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Vision Decreased, CTCAE Grade 2 Vision decreased 10047516 C145099 Grade 2 Vision decreased Grade 2 Vision decreased Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Vision Decreased, CTCAE PT NCI Grade 2 Vision decreased PT CTCAE_v5 ctcae5:C145100 <75-50% of predicted value; limiting instrumental ADL <75-50% of predicted value; limiting instrumental ADL Grade 2 Vital Capacity Abnormal, CTCAE Grade 2 Vital capacity abnormal 10047580 C145100 Grade 2 Vital capacity abnormal Grade 2 Vital capacity abnormal <75-50% of predicted value; limiting instrumental ADL NCI <75-50% of predicted value; limiting instrumental ADL CTCAE_v5 Grade 2 Vital Capacity Abnormal, CTCAE PT NCI Grade 2 Vital capacity abnormal PT CTCAE_v5 ctcae5:C145101 Moderate or persistent change from normal voice; still understandable Moderate or persistent change from normal voice; still understandable Grade 2 Voice Alteration, CTCAE Grade 2 Voice alteration 10047681 C145101 Grade 2 Voice alteration Grade 2 Voice alteration Moderate or persistent change from normal voice; still understandable NCI Moderate or persistent change from normal voice; still understandable CTCAE_v5 Grade 2 Voice Alteration, CTCAE PT NCI Grade 2 Voice alteration PT CTCAE_v5 ctcae5:C145102 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Vulval Infection, CTCAE Grade 2 Vulval infection 10065772 C145102 Grade 2 Vulval infection Grade 2 Vulval infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Vulval Infection, CTCAE PT NCI Grade 2 Vulval infection PT CTCAE_v5 ctcae5:C145103 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Watering Eyes, CTCAE Grade 2 Watering eyes 10047848 C145103 Grade 2 Watering eyes Grade 2 Watering eyes Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Watering Eyes, CTCAE PT NCI Grade 2 Watering eyes PT CTCAE_v5 ctcae5:C145104 Moderate symptoms; medical intervention indicated; limiting instrumental ADL Moderate symptoms; medical intervention indicated; limiting instrumental ADL Grade 2 Wheezing Grade 2 Wheezing, CTCAE 10047924 C145104 Grade 2 Wheezing Grade 2 Wheezing Moderate symptoms; medical intervention indicated; limiting instrumental ADL NCI Moderate symptoms; medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Wheezing PT CTCAE_v5 Grade 2 Wheezing, CTCAE PT NCI ctcae5:C145105 <3000-2000/mm3; <3.0-2.0 x 10e9/L <3000-2000/mm3; <3.0-2.0 x 10e9/L Grade 2 White Blood Cell Decreased, CTCAE Grade 2 White blood cell decreased 10049182 C145105 Grade 2 White blood cell decreased Grade 2 White blood cell decreased <3000-2000/mm3; <3.0-2.0 x 10e9/L NCI <3000-2000/mm3; <3.0-2.0 x 10e9/L CTCAE_v5 Grade 2 White Blood Cell Decreased, CTCAE PT NCI Grade 2 White blood cell decreased PT CTCAE_v5 ctcae5:C145106 Bedside local care indicated Bedside local care indicated Grade 2 Wound Complication, CTCAE Grade 2 Wound complication 10053692 C145106 Grade 2 Wound complication Grade 2 Wound complication Bedside local care indicated NCI Bedside local care indicated CTCAE_v5 Grade 2 Wound Complication, CTCAE PT NCI Grade 2 Wound complication PT CTCAE_v5 ctcae5:C145107 Incisional separation, local care (e.g., suturing) or medical intervention indicated (e.g., analgesic) Incisional separation, local care (e.g., suturing) or medical intervention indicated (e.g., analgesic) Grade 2 Wound Dehiscence, CTCAE Grade 2 Wound dehiscence 10048031 C145107 Grade 2 Wound dehiscence Grade 2 Wound dehiscence Incisional separation, local care (e.g., suturing) or medical intervention indicated (e.g., analgesic) NCI Incisional separation, local care (e.g., suturing) or medical intervention indicated (e.g., analgesic) CTCAE_v5 Grade 2 Wound Dehiscence, CTCAE PT NCI Grade 2 Wound dehiscence PT CTCAE_v5 ctcae5:C145108 Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) Grade 2 Wound Infection, CTCAE Grade 2 Wound infection 10048038 C145108 Grade 2 Wound infection Grade 2 Wound infection Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) NCI Oral intervention indicated (e.g., antibiotic, antifungal, or antiviral) CTCAE_v5 Grade 2 Wound Infection, CTCAE PT NCI Grade 2 Wound infection PT CTCAE_v5 ctcae5:C145109 Limiting instrumental ADL; outpatient operative intervention indicated Limiting instrumental ADL; outpatient operative intervention indicated Grade 2 Wrist Fracture, CTCAE Grade 2 Wrist fracture 10048049 C145109 Grade 2 Wrist fracture Grade 2 Wrist fracture Limiting instrumental ADL; outpatient operative intervention indicated NCI Limiting instrumental ADL; outpatient operative intervention indicated CTCAE_v5 Grade 2 Wrist Fracture, CTCAE PT NCI Grade 2 Wrist fracture PT CTCAE_v5 ctcae5:C145110 Severe discomfort; limiting self care ADL Severe discomfort; limiting self care ADL Grade 3 Abdominal Distension, CTCAE Grade 3 Abdominal distension 10000060 C145110 Grade 3 Abdominal distension Grade 3 Abdominal distension Severe discomfort; limiting self care ADL NCI Severe discomfort; limiting self care ADL CTCAE_v5 Grade 3 Abdominal Distension, CTCAE PT NCI Grade 3 Abdominal distension PT CTCAE_v5 ctcae5:C145111 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Abdominal Infection, CTCAE Grade 3 Abdominal infection 10056519 C145111 Grade 3 Abdominal infection Grade 3 Abdominal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Abdominal Infection, CTCAE PT NCI Grade 3 Abdominal infection PT CTCAE_v5 ctcae5:C145112 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Abdominal Pain, CTCAE Grade 3 Abdominal pain 10000081 C145112 Grade 3 Abdominal pain Grade 3 Abdominal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Abdominal Pain, CTCAE PT NCI Grade 3 Abdominal pain PT CTCAE_v5 ctcae5:C145113 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Abdominal Soft Tissue Necrosis, CTCAE Grade 3 Abdominal soft tissue necrosis 10065775 C145113 Grade 3 Abdominal soft tissue necrosis Grade 3 Abdominal soft tissue necrosis Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Abdominal Soft Tissue Necrosis, CTCAE PT NCI Grade 3 Abdominal soft tissue necrosis PT CTCAE_v5 ctcae5:C145114 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Abducens Nerve Disorder, CTCAE Grade 3 Abducens nerve disorder 10053662 C145114 Grade 3 Abducens nerve disorder Grade 3 Abducens nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Abducens Nerve Disorder, CTCAE PT NCI Grade 3 Abducens nerve disorder PT CTCAE_v5 ctcae5:C145115 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Accessory Nerve Disorder, CTCAE Grade 3 Accessory nerve disorder 10060929 C145115 Grade 3 Accessory nerve disorder Grade 3 Accessory nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Accessory Nerve Disorder, CTCAE PT NCI Grade 3 Accessory nerve disorder PT CTCAE_v5 ctcae5:C145116 pH <7.3 pH <7.3 Grade 3 Acidosis Grade 3 Acidosis, CTCAE 10000486 C145116 Grade 3 Acidosis Grade 3 Acidosis pH <7.3 NCI pH <7.3 CTCAE_v5 Grade 3 Acidosis PT CTCAE_v5 Grade 3 Acidosis, CTCAE PT NCI ctcae5:C145117 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Acoustic Nerve Disorder NOS, CTCAE Grade 3 Acoustic nerve disorder NOS 10000521 C145117 Grade 3 Acoustic nerve disorder NOS Grade 3 Acoustic nerve disorder NOS Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Acoustic Nerve Disorder NOS, CTCAE PT NCI Grade 3 Acoustic nerve disorder NOS PT CTCAE_v5 ctcae5:C145118 >2.5 x ULN; bleeding >2.5 x ULN; bleeding Grade 3 Activated Partial Thromboplastin Time Prolonged, CTCAE Grade 3 Activated partial thromboplastin time prolonged 10000636 C145118 Grade 3 Activated partial thromboplastin time prolonged Grade 3 Activated partial thromboplastin time prolonged >2.5 x ULN; bleeding NCI >2.5 x ULN; bleeding CTCAE_v5 Grade 3 Activated Partial Thromboplastin Time Prolonged, CTCAE PT NCI Grade 3 Activated partial thromboplastin time prolonged PT CTCAE_v5 ctcae5:C145119 Hospitalization indicated Hospitalization indicated Grade 3 Acute Kidney Injury, CTCAE Grade 3 Acute kidney injury 10069339 C145119 Grade 3 Acute kidney injury Grade 3 Acute kidney injury Hospitalization indicated NCI Hospitalization indicated CTCAE_v5 Grade 3 Acute Kidney Injury, CTCAE PT NCI Grade 3 Acute kidney injury PT CTCAE_v5 ctcae5:C145120 Severe restlessness or increased motor activity; limiting self care ADL Severe restlessness or increased motor activity; limiting self care ADL Grade 3 Akathisia Grade 3 Akathisia, CTCAE 10001540 C145120 Grade 3 Akathisia Grade 3 Akathisia Severe restlessness or increased motor activity; limiting self care ADL NCI Severe restlessness or increased motor activity; limiting self care ADL CTCAE_v5 Grade 3 Akathisia PT CTCAE_v5 Grade 3 Akathisia, CTCAE PT NCI ctcae5:C145121 >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal Grade 3 Alanine Aminotransferase Increased, CTCAE Grade 3 Alanine aminotransferase increased 10001551 C145121 Grade 3 Alanine aminotransferase increased Grade 3 Alanine aminotransferase increased >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal NCI >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 3 Alanine Aminotransferase Increased, CTCAE PT NCI Grade 3 Alanine aminotransferase increased PT CTCAE_v5 ctcae5:C145122 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Alcohol Intolerance, CTCAE Grade 3 Alcohol intolerance 10001598 C145122 Grade 3 Alcohol intolerance Grade 3 Alcohol intolerance Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Alcohol Intolerance, CTCAE PT NCI Grade 3 Alcohol intolerance PT CTCAE_v5 ctcae5:C145123 >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal Grade 3 Alkaline Phosphatase Increased, CTCAE Grade 3 Alkaline phosphatase increased 10001675 C145123 Grade 3 Alkaline phosphatase increased Grade 3 Alkaline phosphatase increased >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal NCI >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 3 Alkaline Phosphatase Increased, CTCAE PT NCI Grade 3 Alkaline phosphatase increased PT CTCAE_v5 ctcae5:C145124 pH >7.5 pH >7.5 Grade 3 Alkalosis Grade 3 Alkalosis, CTCAE 10001680 C145124 Grade 3 Alkalosis Grade 3 Alkalosis pH >7.5 NCI pH >7.5 CTCAE_v5 Grade 3 Alkalosis PT CTCAE_v5 Grade 3 Alkalosis, CTCAE PT NCI ctcae5:C145125 Bronchospasm; hospitalization indicated for clinical sequelae; intravenous intervention indicated Bronchospasm; hospitalization indicated for clinical sequelae; intravenous intervention indicated Grade 3 Allergic Reaction, CTCAE Grade 3 Allergic reaction 10001718 C145125 Grade 3 Allergic reaction Grade 3 Allergic reaction Bronchospasm; hospitalization indicated for clinical sequelae; intravenous intervention indicated NCI Bronchospasm; hospitalization indicated for clinical sequelae; intravenous intervention indicated CTCAE_v5 Grade 3 Allergic Reaction, CTCAE PT NCI Grade 3 Allergic reaction PT CTCAE_v5 ctcae5:C145126 Severe; long term memory loss; limiting self care ADL Severe; long term memory loss; limiting self care ADL Grade 3 Amnesia Grade 3 Amnesia, CTCAE 10001949 C145126 Grade 3 Amnesia Grade 3 Amnesia Severe; long term memory loss; limiting self care ADL NCI Severe; long term memory loss; limiting self care ADL CTCAE_v5 Grade 3 Amnesia PT CTCAE_v5 Grade 3 Amnesia, CTCAE PT NCI ctcae5:C145127 Invasive intervention indicated Invasive intervention indicated Grade 3 Anal Fissure, CTCAE Grade 3 Anal fissure 10002153 C145127 Grade 3 Anal fissure Grade 3 Anal fissure Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Anal Fissure, CTCAE PT NCI Grade 3 Anal fissure PT CTCAE_v5 ctcae5:C145128 Invasive intervention indicated Invasive intervention indicated Grade 3 Anal Fistula, CTCAE Grade 3 Anal fistula 10002156 C145128 Grade 3 Anal fistula Grade 3 Anal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Anal Fistula, CTCAE PT NCI Grade 3 Anal fistula PT CTCAE_v5 ctcae5:C145129 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Anal Hemorrhage, CTCAE Grade 3 Anal hemorrhage 10055226 C145129 Grade 3 Anal hemorrhage Grade 3 Anal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Anal Hemorrhage, CTCAE PT NCI Grade 3 Anal hemorrhage PT CTCAE_v5 ctcae5:C145130 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Anal Mucositis, CTCAE Grade 3 Anal mucositis 10065721 C145130 Grade 3 Anal mucositis Grade 3 Anal mucositis Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Anal Mucositis, CTCAE PT NCI Grade 3 Anal mucositis PT CTCAE_v5 ctcae5:C145131 TPN or hospitalization indicated; invasive intervention indicated TPN or hospitalization indicated; invasive intervention indicated Grade 3 Anal Necrosis, CTCAE Grade 3 Anal necrosis 10065722 C145131 Grade 3 Anal necrosis Grade 3 Anal necrosis TPN or hospitalization indicated; invasive intervention indicated NCI TPN or hospitalization indicated; invasive intervention indicated CTCAE_v5 Grade 3 Anal Necrosis, CTCAE PT NCI Grade 3 Anal necrosis PT CTCAE_v5 ctcae5:C145132 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Anal Pain, CTCAE Grade 3 Anal pain 10002167 C145132 Grade 3 Anal pain Grade 3 Anal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Anal Pain, CTCAE PT NCI Grade 3 Anal pain PT CTCAE_v5 ctcae5:C145133 Symptomatic and severely altered GI function; non-emergent operative intervention indicated; TPN or hospitalization indicated Symptomatic and severely altered GI function; non-emergent operative intervention indicated; TPN or hospitalization indicated Grade 3 Anal Stenosis, CTCAE Grade 3 Anal stenosis 10002176 C145133 Grade 3 Anal stenosis Grade 3 Anal stenosis Symptomatic and severely altered GI function; non-emergent operative intervention indicated; TPN or hospitalization indicated NCI Symptomatic and severely altered GI function; non-emergent operative intervention indicated; TPN or hospitalization indicated CTCAE_v5 Grade 3 Anal Stenosis, CTCAE PT NCI Grade 3 Anal stenosis PT CTCAE_v5 ctcae5:C145134 Severely altered GI function; TPN indicated; elective invasive intervention indicated Severely altered GI function; TPN indicated; elective invasive intervention indicated Grade 3 Anal Ulcer, CTCAE Grade 3 Anal ulcer 10002180 C145134 Grade 3 Anal ulcer Grade 3 Anal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Anal Ulcer, CTCAE PT NCI Grade 3 Anal ulcer PT CTCAE_v5 ctcae5:C145135 Symptomatic bronchospasm, with or without urticaria; parenteral intervention indicated; allergy-related edema/angioedema; hypotension Symptomatic bronchospasm, with or without urticaria; parenteral intervention indicated; allergy-related edema/angioedema; hypotension Grade 3 Anaphylaxis Grade 3 Anaphylaxis, CTCAE 10002218 C145135 Grade 3 Anaphylaxis Grade 3 Anaphylaxis Symptomatic bronchospasm, with or without urticaria; parenteral intervention indicated; allergy-related edema/angioedema; hypotension NCI Symptomatic bronchospasm, with or without urticaria; parenteral intervention indicated; allergy-related edema/angioedema; hypotension CTCAE_v5 Grade 3 Anaphylaxis PT CTCAE_v5 Grade 3 Anaphylaxis, CTCAE PT NCI ctcae5:C145136 Hgb <8.0 g/dL; <4.9 mmol/L; <80 g/L; transfusion indicated Hgb <8.0 g/dL; <4.9 mmol/L; <80 g/L; transfusion indicated Grade 3 Anemia Grade 3 Anemia, CTCAE 10002272 C145136 Grade 3 Anemia Grade 3 Anemia Hgb <8.0 g/dL; <4.9 mmol/L; <80 g/L; transfusion indicated NCI Hgb <8.0 g/dL; <4.9 mmol/L; <80 g/L; transfusion indicated CTCAE_v5 Grade 3 Anemia PT CTCAE_v5 Grade 3 Anemia, CTCAE PT NCI ctcae5:C145137 Limiting self care ADL; elective operative intervention indicated requiring hospitalization Limiting self care ADL; elective operative intervention indicated requiring hospitalization Grade 3 Ankle Fracture, CTCAE Grade 3 Ankle fracture 10002544 C145137 Grade 3 Ankle fracture Grade 3 Ankle fracture Limiting self care ADL; elective operative intervention indicated requiring hospitalization NCI Limiting self care ADL; elective operative intervention indicated requiring hospitalization CTCAE_v5 Grade 3 Ankle Fracture, CTCAE PT NCI Grade 3 Ankle fracture PT CTCAE_v5 ctcae5:C145138 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Anorectal Infection, CTCAE Grade 3 Anorectal infection 10061640 C145138 Grade 3 Anorectal infection Grade 3 Anorectal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Anorectal Infection, CTCAE PT NCI Grade 3 Anorectal infection PT CTCAE_v5 ctcae5:C145139 Severe symptoms; limiting self care ADL; repair or revision indicated Severe symptoms; limiting self care ADL; repair or revision indicated Grade 3 Aortic Injury, CTCAE Grade 3 Aortic injury 10002899 C145139 Grade 3 Aortic injury Grade 3 Aortic injury Severe symptoms; limiting self care ADL; repair or revision indicated NCI Severe symptoms; limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Aortic Injury, CTCAE PT NCI Grade 3 Aortic injury PT CTCAE_v5 ctcae5:C145140 Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Grade 3 Aortic Valve Disease, CTCAE Grade 3 Aortic valve disease 10061589 C145140 Grade 3 Aortic valve disease Grade 3 Aortic valve disease Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention NCI Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention CTCAE_v5 Grade 3 Aortic Valve Disease, CTCAE PT NCI Grade 3 Aortic valve disease PT CTCAE_v5 ctcae5:C145141 Voicelessness; unable to speak Voicelessness; unable to speak Grade 3 Aphonia Grade 3 Aphonia, CTCAE 10002953 C145141 Grade 3 Aphonia Grade 3 Aphonia Voicelessness; unable to speak NCI Voicelessness; unable to speak CTCAE_v5 Grade 3 Aphonia PT CTCAE_v5 Grade 3 Aphonia, CTCAE PT NCI ctcae5:C145142 Medical intervention indicated; operative intervention indicated Medical intervention indicated; operative intervention indicated Grade 3 Appendicitis Perforated, CTCAE Grade 3 Appendicitis perforated 10003012 C145142 Grade 3 Appendicitis perforated Grade 3 Appendicitis perforated Medical intervention indicated; operative intervention indicated NCI Medical intervention indicated; operative intervention indicated CTCAE_v5 Grade 3 Appendicitis Perforated, CTCAE PT NCI Grade 3 Appendicitis perforated PT CTCAE_v5 ctcae5:C145143 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Appendicitis Grade 3 Appendicitis, CTCAE 10003011 C145143 Grade 3 Appendicitis Grade 3 Appendicitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Appendicitis PT CTCAE_v5 Grade 3 Appendicitis, CTCAE PT NCI ctcae5:C145144 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Arachnoiditis Grade 3 Arachnoiditis, CTCAE 10003074 C145144 Grade 3 Arachnoiditis Grade 3 Arachnoiditis Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Arachnoiditis PT CTCAE_v5 Grade 3 Arachnoiditis, CTCAE PT NCI ctcae5:C145145 Severe symptoms; limiting self care ADL; repair or revision indicated Severe symptoms; limiting self care ADL; repair or revision indicated Grade 3 Arterial Injury, CTCAE Grade 3 Arterial injury 10003162 C145145 Grade 3 Arterial injury Grade 3 Arterial injury Severe symptoms; limiting self care ADL; repair or revision indicated NCI Severe symptoms; limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Arterial Injury, CTCAE PT NCI Grade 3 Arterial injury PT CTCAE_v5 ctcae5:C145146 Urgent intervention indicated Urgent intervention indicated Grade 3 Arterial Thromboembolism, CTCAE Grade 3 Arterial thromboembolism 10073529 C145146 Grade 3 Arterial thromboembolism Grade 3 Arterial thromboembolism Urgent intervention indicated NCI Urgent intervention indicated CTCAE_v5 Grade 3 Arterial Thromboembolism, CTCAE PT NCI Grade 3 Arterial thromboembolism PT CTCAE_v5 ctcae5:C145147 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Arteritis Infective, CTCAE Grade 3 Arteritis infective 10065744 C145147 Grade 3 Arteritis infective Grade 3 Arteritis infective IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Arteritis Infective, CTCAE PT NCI Grade 3 Arteritis infective PT CTCAE_v5 ctcae5:C145148 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Arthralgia Grade 3 Arthralgia, CTCAE 10003239 C145148 Grade 3 Arthralgia Grade 3 Arthralgia Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Arthralgia PT CTCAE_v5 Grade 3 Arthralgia, CTCAE PT NCI ctcae5:C145149 Severe pain associated with signs of inflammation, erythema, or joint swelling; irreversible joint damage; limiting self care ADL Severe pain associated with signs of inflammation, erythema, or joint swelling; irreversible joint damage; limiting self care ADL Grade 3 Arthritis Grade 3 Arthritis, CTCAE 10003246 C145149 Grade 3 Arthritis Grade 3 Arthritis Severe pain associated with signs of inflammation, erythema, or joint swelling; irreversible joint damage; limiting self care ADL NCI Severe pain associated with signs of inflammation, erythema, or joint swelling; irreversible joint damage; limiting self care ADL CTCAE_v5 Grade 3 Arthritis PT CTCAE_v5 Grade 3 Arthritis, CTCAE PT NCI ctcae5:C145150 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Ascites Grade 3 Ascites, CTCAE 10003445 C145150 Grade 3 Ascites Grade 3 Ascites Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Ascites PT CTCAE_v5 Grade 3 Ascites, CTCAE PT NCI ctcae5:C145151 >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal Grade 3 Aspartate Aminotransferase Increased, CTCAE Grade 3 Aspartate aminotransferase increased 10003481 C145151 Grade 3 Aspartate aminotransferase increased Grade 3 Aspartate aminotransferase increased >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal NCI >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 3 Aspartate Aminotransferase Increased, CTCAE PT NCI Grade 3 Aspartate aminotransferase increased PT CTCAE_v5 ctcae5:C145152 Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset Grade 3 Atrioventricular Block Complete, CTCAE Grade 3 Atrioventricular block complete 10003673 C145152 Grade 3 Atrioventricular block complete Grade 3 Atrioventricular block complete Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset NCI Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset CTCAE_v5 Grade 3 Atrioventricular Block Complete, CTCAE PT NCI Grade 3 Atrioventricular block complete PT CTCAE_v5 ctcae5:C145153 Autoimmune reactions involving major organ (e.g., colitis, anemia, myocarditis, kidney) Autoimmune reactions involving major organ (e.g., colitis, anemia, myocarditis, kidney) Grade 3 Autoimmune Disorder, CTCAE Grade 3 Autoimmune disorder 10061664 C145153 Grade 3 Autoimmune disorder Grade 3 Autoimmune disorder Autoimmune reactions involving major organ (e.g., colitis, anemia, myocarditis, kidney) NCI Autoimmune reactions involving major organ (e.g., colitis, anemia, myocarditis, kidney) CTCAE_v5 Grade 3 Autoimmune Disorder, CTCAE PT NCI Grade 3 Autoimmune disorder PT CTCAE_v5 ctcae5:C145154 Severe symptoms; limiting self care ADL; elective operative intervention indicated Severe symptoms; limiting self care ADL; elective operative intervention indicated Grade 3 Avascular Necrosis, CTCAE Grade 3 Avascular necrosis 10066480 C145154 Grade 3 Avascular necrosis Grade 3 Avascular necrosis Severe symptoms; limiting self care ADL; elective operative intervention indicated NCI Severe symptoms; limiting self care ADL; elective operative intervention indicated CTCAE_v5 Grade 3 Avascular Necrosis, CTCAE PT NCI Grade 3 Avascular necrosis PT CTCAE_v5 ctcae5:C145155 Severely altered GI function; invasive intervention indicated Severely altered GI function; invasive intervention indicated Grade 3 Bile Duct Stenosis, CTCAE Grade 3 Bile duct stenosis 10051341 C145155 Grade 3 Bile duct stenosis Grade 3 Bile duct stenosis Severely altered GI function; invasive intervention indicated NCI Severely altered GI function; invasive intervention indicated CTCAE_v5 Grade 3 Bile Duct Stenosis, CTCAE PT NCI Grade 3 Bile duct stenosis PT CTCAE_v5 ctcae5:C145156 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Biliary Anastomotic Leak, CTCAE Grade 3 Biliary anastomotic leak 10050458 C145156 Grade 3 Biliary anastomotic leak Grade 3 Biliary anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Biliary Anastomotic Leak, CTCAE PT NCI Grade 3 Biliary anastomotic leak PT CTCAE_v5 ctcae5:C145157 Invasive intervention indicated Invasive intervention indicated Grade 3 Biliary Fistula, CTCAE Grade 3 Biliary fistula 10004665 C145157 Grade 3 Biliary fistula Grade 3 Biliary fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Biliary Fistula, CTCAE PT NCI Grade 3 Biliary fistula PT CTCAE_v5 ctcae5:C145158 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Biliary Tract Infection, CTCAE Grade 3 Biliary tract infection 10061695 C145158 Grade 3 Biliary tract infection Grade 3 Biliary tract infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Biliary Tract Infection, CTCAE PT NCI Grade 3 Biliary tract infection PT CTCAE_v5 ctcae5:C145159 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Bladder Anastomotic Leak, CTCAE Grade 3 Bladder anastomotic leak 10065802 C145159 Grade 3 Bladder anastomotic leak Grade 3 Bladder anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Bladder Anastomotic Leak, CTCAE PT NCI Grade 3 Bladder anastomotic leak PT CTCAE_v5 ctcae5:C145160 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Bladder Infection, CTCAE Grade 3 Bladder infection 10005047 C145160 Grade 3 Bladder infection Grade 3 Bladder infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Bladder Infection, CTCAE PT NCI Grade 3 Bladder infection PT CTCAE_v5 ctcae5:C145162 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Grade 3 Blood and lymphatic system disorders - Other, specify 10005329 C145162 Grade 3 Blood and lymphatic system disorders - Other, specify Grade 3 Blood and lymphatic system disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Grade 3 Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C145163 Hospitalization indicated Hospitalization indicated Grade 3 Blood Antidiuretic Hormone Abnormal, CTCAE Grade 3 Blood antidiuretic hormone abnormal 10005332 C145163 Grade 3 Blood antidiuretic hormone abnormal Grade 3 Blood antidiuretic hormone abnormal Hospitalization indicated NCI Hospitalization indicated CTCAE_v5 Grade 3 Blood Antidiuretic Hormone Abnormal, CTCAE PT NCI Grade 3 Blood antidiuretic hormone abnormal PT CTCAE_v5 ctcae5:C145164 >3.0-10.0 x ULN if baseline was normal; >3.0-10.0 x baseline if baseline was abnormal >3.0-10.0 x ULN if baseline was normal; >3.0-10.0 x baseline if baseline was abnormal Grade 3 Blood Bilirubin Increased, CTCAE Grade 3 Blood bilirubin increased 10005364 C145164 Grade 3 Blood bilirubin increased Grade 3 Blood bilirubin increased >3.0-10.0 x ULN if baseline was normal; >3.0-10.0 x baseline if baseline was abnormal NCI >3.0-10.0 x ULN if baseline was normal; >3.0-10.0 x baseline if baseline was abnormal CTCAE_v5 Grade 3 Blood Bilirubin Increased, CTCAE PT NCI Grade 3 Blood bilirubin increased PT CTCAE_v5 ctcae5:C145165 Hospitalization indicated Hospitalization indicated Grade 3 Blood Corticotrophin Decreased, CTCAE Grade 3 Blood corticotrophin decreased 10005452 C145165 Grade 3 Blood corticotrophin decreased Grade 3 Blood corticotrophin decreased Hospitalization indicated NCI Hospitalization indicated CTCAE_v5 Grade 3 Blood Corticotrophin Decreased, CTCAE PT NCI Grade 3 Blood corticotrophin decreased PT CTCAE_v5 ctcae5:C145166 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Blood Gonadotrophin Abnormal, CTCAE Grade 3 Blood gonadotrophin abnormal 10005561 C145166 Grade 3 Blood gonadotrophin abnormal Grade 3 Blood gonadotrophin abnormal Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Blood Gonadotrophin Abnormal, CTCAE PT NCI Grade 3 Blood gonadotrophin abnormal PT CTCAE_v5 ctcae5:C145167 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Bone Infection, CTCAE Grade 3 Bone infection 10061017 C145167 Grade 3 Bone infection Grade 3 Bone infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Bone Infection, CTCAE PT NCI Grade 3 Bone infection PT CTCAE_v5 ctcae5:C145168 Severely hypocellular or >50-<=75% reduction cellularity from normal for age Severely hypocellular or >50-<=75% reduction cellularity from normal for age Grade 3 Bone Marrow Hypocellular, CTCAE Grade 3 Bone marrow hypocellular 10048580 C145168 Grade 3 Bone marrow hypocellular Grade 3 Bone marrow hypocellular Severely hypocellular or >50-<=75% reduction cellularity from normal for age NCI Severely hypocellular or >50-<=75% reduction cellularity from normal for age CTCAE_v5 Grade 3 Bone Marrow Hypocellular, CTCAE PT NCI Grade 3 Bone marrow hypocellular PT CTCAE_v5 ctcae5:C145169 Asymmetry >1/3 of breast volume; severe atrophy Asymmetry >1/3 of breast volume; severe atrophy Grade 3 Breast Atrophy, CTCAE Grade 3 Breast atrophy 10006179 C145169 Grade 3 Breast atrophy Grade 3 Breast atrophy Asymmetry >1/3 of breast volume; severe atrophy NCI Asymmetry >1/3 of breast volume; severe atrophy CTCAE_v5 Grade 3 Breast Atrophy, CTCAE PT NCI Grade 3 Breast atrophy PT CTCAE_v5 ctcae5:C145170 IV antibiotic, antifungal, or antiviral intervention indicated; severe infection; axillary adenitis IV antibiotic, antifungal, or antiviral intervention indicated; severe infection; axillary adenitis Grade 3 Breast Infection, CTCAE Grade 3 Breast infection 10006259 C145170 Grade 3 Breast infection Grade 3 Breast infection IV antibiotic, antifungal, or antiviral intervention indicated; severe infection; axillary adenitis NCI IV antibiotic, antifungal, or antiviral intervention indicated; severe infection; axillary adenitis CTCAE_v5 Grade 3 Breast Infection, CTCAE PT NCI Grade 3 Breast infection PT CTCAE_v5 ctcae5:C145171 Invasive intervention indicated Invasive intervention indicated Grade 3 Bronchial Fistula, CTCAE Grade 3 Bronchial fistula 10006437 C145171 Grade 3 Bronchial fistula Grade 3 Bronchial fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Bronchial Fistula, CTCAE PT NCI Grade 3 Bronchial fistula PT CTCAE_v5 ctcae5:C145172 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Bronchial Infection, CTCAE Grade 3 Bronchial infection 10055078 C145172 Grade 3 Bronchial infection Grade 3 Bronchial infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Bronchial Infection, CTCAE PT NCI Grade 3 Bronchial infection PT CTCAE_v5 ctcae5:C145173 Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) Grade 3 Bronchial Obstruction, CTCAE Grade 3 Bronchial obstruction 10006440 C145173 Grade 3 Bronchial obstruction Grade 3 Bronchial obstruction Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) NCI Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) CTCAE_v5 Grade 3 Bronchial Obstruction, CTCAE PT NCI Grade 3 Bronchial obstruction PT CTCAE_v5 ctcae5:C145174 Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) Grade 3 Bronchial Stricture, CTCAE Grade 3 Bronchial stricture 10063524 C145174 Grade 3 Bronchial stricture Grade 3 Bronchial stricture Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) NCI Shortness of breath with stridor; endoscopic intervention indicated (e.g., laser, stent placement) CTCAE_v5 Grade 3 Bronchial Stricture, CTCAE PT NCI Grade 3 Bronchial stricture PT CTCAE_v5 ctcae5:C145175 Hospitalization; invasive intervention indicated Hospitalization; invasive intervention indicated Grade 3 Bronchopleural Fistula, CTCAE Grade 3 Bronchopleural fistula 10053481 C145175 Grade 3 Bronchopleural fistula Grade 3 Bronchopleural fistula Hospitalization; invasive intervention indicated NCI Hospitalization; invasive intervention indicated CTCAE_v5 Grade 3 Bronchopleural Fistula, CTCAE PT NCI Grade 3 Bronchopleural fistula PT CTCAE_v5 ctcae5:C145176 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Bronchopulmonary Hemorrhage, CTCAE Grade 3 Bronchopulmonary hemorrhage 10065746 C145176 Grade 3 Bronchopulmonary hemorrhage Grade 3 Bronchopulmonary hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Bronchopulmonary Hemorrhage, CTCAE PT NCI Grade 3 Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C145177 Limiting self care ADL; supplemental oxygen indicated Limiting self care ADL; supplemental oxygen indicated Grade 3 Bronchospasm Grade 3 Bronchospasm, CTCAE 10006482 C145177 Grade 3 Bronchospasm Grade 3 Bronchospasm Limiting self care ADL; supplemental oxygen indicated NCI Limiting self care ADL; supplemental oxygen indicated CTCAE_v5 Grade 3 Bronchospasm PT CTCAE_v5 Grade 3 Bronchospasm, CTCAE PT NCI ctcae5:C145178 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; asterixis; mild encephalopathy Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; asterixis; mild encephalopathy Grade 3 Budd-Chiari Syndrome, CTCAE Grade 3 Budd-Chiari syndrome 10006537 C145178 Grade 3 Budd-Chiari syndrome Grade 3 Budd-Chiari syndrome Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; asterixis; mild encephalopathy NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; asterixis; mild encephalopathy CTCAE_v5 Grade 3 Budd-Chiari Syndrome, CTCAE PT NCI Grade 3 Budd-Chiari syndrome PT CTCAE_v5 ctcae5:C145179 Blisters covering >30% BSA; limiting self care ADL Blisters covering >30% BSA; limiting self care ADL Grade 3 Bullous Dermatitis, CTCAE Grade 3 Bullous dermatitis 10006556 C145179 Grade 3 Bullous dermatitis Grade 3 Bullous dermatitis Blisters covering >30% BSA; limiting self care ADL NCI Blisters covering >30% BSA; limiting self care ADL CTCAE_v5 Grade 3 Bullous Dermatitis, CTCAE PT NCI Grade 3 Bullous dermatitis PT CTCAE_v5 ctcae5:C145180 Severe symptoms; intervention indicated Severe symptoms; intervention indicated Grade 3 Capillary Leak Syndrome, CTCAE Grade 3 Capillary leak syndrome 10007196 C145180 Grade 3 Capillary leak syndrome Grade 3 Capillary leak syndrome Severe symptoms; intervention indicated NCI Severe symptoms; intervention indicated CTCAE_v5 Grade 3 Capillary Leak Syndrome, CTCAE PT NCI Grade 3 Capillary leak syndrome PT CTCAE_v5 ctcae5:C145181 Asymptomatic decrease of >8 units drop; >5 units drop along with the presence of pulmonary symptoms (e.g., >Grade 2 hypoxia or >Grade 2 dyspnea); intervention indicated Asymptomatic decrease of >8 units drop; >5 units drop along with the presence of pulmonary symptoms (e.g., >Grade 2 hypoxia or >Grade 2 dyspnea); intervention indicated Grade 3 Carbon Monoxide Diffusing Capacity Decreased, CTCAE Grade 3 Carbon monoxide diffusing capacity decreased 10065906 C145181 Grade 3 Carbon monoxide diffusing capacity decreased Grade 3 Carbon monoxide diffusing capacity decreased Asymptomatic decrease of >8 units drop; >5 units drop along with the presence of pulmonary symptoms (e.g., >Grade 2 hypoxia or >Grade 2 dyspnea); intervention indicated NCI Asymptomatic decrease of >8 units drop; >5 units drop along with the presence of pulmonary symptoms (e.g., >Grade 2 hypoxia or >Grade 2 dyspnea); intervention indicated CTCAE_v5 Grade 3 Carbon Monoxide Diffusing Capacity Decreased, CTCAE PT NCI Grade 3 Carbon monoxide diffusing capacity decreased PT CTCAE_v5 ctcae5:C145182 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Cardiac Disorders - Other, Specify, CTCAE Grade 3 Cardiac disorders - Other, specify 10007541 C145182 Grade 3 Cardiac disorders - Other, specify Grade 3 Cardiac disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Cardiac Disorders - Other, Specify, CTCAE PT NCI Grade 3 Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C145183 Levels consistent with myocardial infarction as defined by the manufacturer Levels consistent with myocardial infarction as defined by the manufacturer Grade 3 Cardiac Troponin I Increased, CTCAE Grade 3 Cardiac troponin I increased 10007612 C145183 Grade 3 Cardiac troponin I increased Grade 3 Cardiac troponin I increased Levels consistent with myocardial infarction as defined by the manufacturer NCI Levels consistent with myocardial infarction as defined by the manufacturer CTCAE_v5 Grade 3 Cardiac Troponin I Increased, CTCAE PT NCI Grade 3 Cardiac troponin I increased PT CTCAE_v5 ctcae5:C145184 Levels consistent with myocardial infarction as defined by the manufacturer Levels consistent with myocardial infarction as defined by the manufacturer Grade 3 Cardiac Troponin T Increased, CTCAE Grade 3 Cardiac troponin T increased 10007613 C145184 Grade 3 Cardiac troponin T increased Grade 3 Cardiac troponin T increased Levels consistent with myocardial infarction as defined by the manufacturer NCI Levels consistent with myocardial infarction as defined by the manufacturer CTCAE_v5 Grade 3 Cardiac Troponin T Increased, CTCAE PT NCI Grade 3 Cardiac troponin T increased PT CTCAE_v5 ctcae5:C145185 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Catheter Related Infection, CTCAE Grade 3 Catheter related infection 10007810 C145185 Grade 3 Catheter related infection Grade 3 Catheter related infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Catheter Related Infection, CTCAE PT NCI Grade 3 Catheter related infection PT CTCAE_v5 ctcae5:C145186 <200-50/mm3; <0.2 x 0.05-10e9/L <200-50/mm3; <0.2 x 0.05-10e9/L Grade 3 CD4 Lymphocytes Decreased, CTCAE Grade 3 CD4 lymphocytes decreased 10007839 C145186 Grade 3 CD4 lymphocytes decreased Grade 3 CD4 lymphocytes decreased <200-50/mm3; <0.2 x 0.05-10e9/L NCI <200-50/mm3; <0.2 x 0.05-10e9/L CTCAE_v5 Grade 3 CD4 Lymphocytes Decreased, CTCAE PT NCI Grade 3 CD4 lymphocytes decreased PT CTCAE_v5 ctcae5:C145187 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Cecal Hemorrhage, CTCAE Grade 3 Cecal hemorrhage 10065747 C145187 Grade 3 Cecal hemorrhage Grade 3 Cecal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Cecal Hemorrhage, CTCAE PT NCI Grade 3 Cecal hemorrhage PT CTCAE_v5 ctcae5:C145188 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Cecal Infection, CTCAE Grade 3 Cecal infection 10065761 C145188 Grade 3 Cecal infection Grade 3 Cecal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Cecal Infection, CTCAE PT NCI Grade 3 Cecal infection PT CTCAE_v5 ctcae5:C145189 Severe symptoms; medical intervention indicated Severe symptoms; medical intervention indicated Grade 3 Central Nervous System Necrosis, CTCAE Grade 3 Central nervous system necrosis 10065784 C145189 Grade 3 Central nervous system necrosis Grade 3 Central nervous system necrosis Severe symptoms; medical intervention indicated NCI Severe symptoms; medical intervention indicated CTCAE_v5 Grade 3 Central Nervous System Necrosis, CTCAE PT NCI Grade 3 Central nervous system necrosis PT CTCAE_v5 ctcae5:C145190 Severe symptoms; medical intervention indicated Severe symptoms; medical intervention indicated Grade 3 Cerebrospinal Fluid Leakage, CTCAE Grade 3 Cerebrospinal fluid leakage 10008164 C145190 Grade 3 Cerebrospinal fluid leakage Grade 3 Cerebrospinal fluid leakage Severe symptoms; medical intervention indicated NCI Severe symptoms; medical intervention indicated CTCAE_v5 Grade 3 Cerebrospinal Fluid Leakage, CTCAE PT NCI Grade 3 Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C145191 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Cervicitis Infection, CTCAE Grade 3 Cervicitis infection 10008330 C145191 Grade 3 Cervicitis infection Grade 3 Cervicitis infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Cervicitis Infection, CTCAE PT NCI Grade 3 Cervicitis infection PT CTCAE_v5 ctcae5:C145192 Pain at rest; limiting self care ADL; cardiac catheterization; new onset cardiac chest pain; unstable angina Pain at rest; limiting self care ADL; cardiac catheterization; new onset cardiac chest pain; unstable angina Grade 3 Chest Pain - Cardiac, CTCAE Grade 3 Chest pain - cardiac 10008481 C145192 Grade 3 Chest pain - cardiac Grade 3 Chest pain - cardiac Pain at rest; limiting self care ADL; cardiac catheterization; new onset cardiac chest pain; unstable angina NCI Pain at rest; limiting self care ADL; cardiac catheterization; new onset cardiac chest pain; unstable angina CTCAE_v5 Grade 3 Chest Pain - Cardiac, CTCAE PT NCI Grade 3 Chest pain - cardiac PT CTCAE_v5 ctcae5:C145193 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Chest Wall Necrosis, CTCAE Grade 3 Chest wall necrosis 10048831 C145193 Grade 3 Chest wall necrosis Grade 3 Chest wall necrosis Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Chest Wall Necrosis, CTCAE PT NCI Grade 3 Chest wall necrosis PT CTCAE_v5 ctcae5:C145194 Severe or prolonged, not responsive to narcotics Severe or prolonged, not responsive to narcotics Grade 3 Chills Grade 3 Chills, CTCAE 10008531 C145194 Grade 3 Chills Grade 3 Chills Severe or prolonged, not responsive to narcotics NCI Severe or prolonged, not responsive to narcotics CTCAE_v5 Grade 3 Chills PT CTCAE_v5 Grade 3 Chills, CTCAE PT NCI ctcae5:C145195 >400-500 mg/dL; >10.34-12.92 mmol/L >400-500 mg/dL; >10.34-12.92 mmol/L Grade 3 Cholesterol High, CTCAE Grade 3 Cholesterol high 10008661 C145195 Grade 3 Cholesterol high Grade 3 Cholesterol high >400-500 mg/dL; >10.34-12.92 mmol/L NCI >400-500 mg/dL; >10.34-12.92 mmol/L CTCAE_v5 Grade 3 Cholesterol High, CTCAE PT NCI Grade 3 Cholesterol high PT CTCAE_v5 ctcae5:C145196 eGFR or CrCl 29-15 ml/min/1.73 m2 eGFR or CrCl 29-15 ml/min/1.73 m2 Grade 3 Chronic Kidney Disease, CTCAE Grade 3 Chronic kidney disease 10064848 C145196 Grade 3 Chronic kidney disease Grade 3 Chronic kidney disease eGFR or CrCl 29-15 ml/min/1.73 m2 NCI eGFR or CrCl 29-15 ml/min/1.73 m2 CTCAE_v5 Grade 3 Chronic Kidney Disease, CTCAE PT NCI Grade 3 Chronic kidney disease PT CTCAE_v5 ctcae5:C145197 Severe symptoms; elective operative intervention indicated Severe symptoms; elective operative intervention indicated Grade 3 Chylous Ascites, CTCAE Grade 3 Chylous ascites 10009167 C145197 Grade 3 Chylous ascites Grade 3 Chylous ascites Severe symptoms; elective operative intervention indicated NCI Severe symptoms; elective operative intervention indicated CTCAE_v5 Grade 3 Chylous Ascites, CTCAE PT NCI Grade 3 Chylous ascites PT CTCAE_v5 ctcae5:C145198 Invasive intervention indicated Invasive intervention indicated Grade 3 Colonic Fistula, CTCAE Grade 3 Colonic fistula 10009995 C145198 Grade 3 Colonic fistula Grade 3 Colonic fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Colonic Fistula, CTCAE PT NCI Grade 3 Colonic fistula PT CTCAE_v5 ctcae5:C145199 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Colonic Hemorrhage, CTCAE Grade 3 Colonic hemorrhage 10009998 C145199 Grade 3 Colonic hemorrhage Grade 3 Colonic hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Colonic Hemorrhage, CTCAE PT NCI Grade 3 Colonic hemorrhage PT CTCAE_v5 ctcae5:C145200 Hospitalization indicated; invasive intervention indicated Hospitalization indicated; invasive intervention indicated Grade 3 Colonic Obstruction, CTCAE Grade 3 Colonic obstruction 10010000 C145200 Grade 3 Colonic obstruction Grade 3 Colonic obstruction Hospitalization indicated; invasive intervention indicated NCI Hospitalization indicated; invasive intervention indicated CTCAE_v5 Grade 3 Colonic Obstruction, CTCAE PT NCI Grade 3 Colonic obstruction PT CTCAE_v5 ctcae5:C145201 Invasive intervention indicated Invasive intervention indicated Grade 3 Colonic Perforation, CTCAE Grade 3 Colonic perforation 10010001 C145201 Grade 3 Colonic perforation Grade 3 Colonic perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Colonic Perforation, CTCAE PT NCI Grade 3 Colonic perforation PT CTCAE_v5 ctcae5:C145202 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Colonic Stenosis, CTCAE Grade 3 Colonic stenosis 10010004 C145202 Grade 3 Colonic stenosis Grade 3 Colonic stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Colonic Stenosis, CTCAE PT NCI Grade 3 Colonic stenosis PT CTCAE_v5 ctcae5:C145203 Severely altered GI function; TPN indicated; elective invasive intervention indicated Severely altered GI function; TPN indicated; elective invasive intervention indicated Grade 3 Colonic Ulcer, CTCAE Grade 3 Colonic ulcer 10010006 C145203 Grade 3 Colonic ulcer Grade 3 Colonic ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Colonic Ulcer, CTCAE PT NCI Grade 3 Colonic ulcer PT CTCAE_v5 ctcae5:C145204 Severe impairment in attention or decreased level of concentration; limiting self care ADL Severe impairment in attention or decreased level of concentration; limiting self care ADL Grade 3 Concentration Impairment, CTCAE Grade 3 Concentration impairment 10010250 C145204 Grade 3 Concentration impairment Grade 3 Concentration impairment Severe impairment in attention or decreased level of concentration; limiting self care ADL NCI Severe impairment in attention or decreased level of concentration; limiting self care ADL CTCAE_v5 Grade 3 Concentration Impairment, CTCAE PT NCI Grade 3 Concentration impairment PT CTCAE_v5 ctcae5:C145205 Symptomatic, urgent intervention indicated Symptomatic, urgent intervention indicated Grade 3 Conduction Disorder, CTCAE Grade 3 Conduction disorder 10010276 C145205 Grade 3 Conduction disorder Grade 3 Conduction disorder Symptomatic, urgent intervention indicated NCI Symptomatic, urgent intervention indicated CTCAE_v5 Grade 3 Conduction Disorder, CTCAE PT NCI Grade 3 Conduction disorder PT CTCAE_v5 ctcae5:C145206 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Grade 3 Congenital, familial and genetic disorders - Other, specify 10010331 C145206 Grade 3 Congenital, familial and genetic disorders - Other, specify Grade 3 Congenital, familial and genetic disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Grade 3 Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C145207 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Conjunctivitis Infective, CTCAE Grade 3 Conjunctivitis infective 10010742 C145207 Grade 3 Conjunctivitis infective Grade 3 Conjunctivitis infective IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Conjunctivitis Infective, CTCAE PT NCI Grade 3 Conjunctivitis infective PT CTCAE_v5 ctcae5:C145208 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Conjunctivitis Grade 3 Conjunctivitis, CTCAE 10010741 C145208 Grade 3 Conjunctivitis Grade 3 Conjunctivitis Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Conjunctivitis PT CTCAE_v5 Grade 3 Conjunctivitis, CTCAE PT NCI ctcae5:C145209 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Corneal Infection, CTCAE Grade 3 Corneal infection 10061788 C145209 Grade 3 Corneal infection Grade 3 Corneal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Corneal Infection, CTCAE PT NCI Grade 3 Corneal infection PT CTCAE_v5 ctcae5:C145210 Corneal ulcer without perforation in the affected eye Corneal ulcer without perforation in the affected eye Grade 3 Corneal Ulcer, CTCAE Grade 3 Corneal ulcer 10048492 C145210 Grade 3 Corneal ulcer Grade 3 Corneal ulcer Corneal ulcer without perforation in the affected eye NCI Corneal ulcer without perforation in the affected eye CTCAE_v5 Grade 3 Corneal Ulcer, CTCAE PT NCI Grade 3 Corneal ulcer PT CTCAE_v5 ctcae5:C145211 >5 x ULN-10 x ULN >5 x ULN-10 x ULN Grade 3 CPK Increased, CTCAE Grade 3 CPK increased 10011268 C145211 Grade 3 CPK increased Grade 3 CPK increased >5 x ULN-10 x ULN NCI >5 x ULN-10 x ULN CTCAE_v5 Grade 3 CPK Increased, CTCAE PT NCI Grade 3 CPK increased PT CTCAE_v5 ctcae5:C145212 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Cranial Nerve Infection, CTCAE Grade 3 Cranial nerve infection 10065765 C145212 Grade 3 Cranial nerve infection Grade 3 Cranial nerve infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Cranial Nerve Infection, CTCAE PT NCI Grade 3 Cranial nerve infection PT CTCAE_v5 ctcae5:C145213 >3.0 x baseline; >3.0-6.0 x ULN >3.0 x baseline; >3.0-6.0 x ULN Grade 3 Creatinine Increased, CTCAE Grade 3 Creatinine increased 10011368 C145213 Grade 3 Creatinine increased Grade 3 Creatinine increased >3.0 x baseline; >3.0-6.0 x ULN NCI >3.0 x baseline; >3.0-6.0 x ULN CTCAE_v5 Grade 3 Creatinine Increased, CTCAE PT NCI Grade 3 Creatinine increased PT CTCAE_v5 ctcae5:C145214 Severe symptoms, medical intervention or hospitalization indicated Severe symptoms, medical intervention or hospitalization indicated Grade 3 Cushingoid Grade 3 Cushingoid, CTCAE 10011655 C145214 Grade 3 Cushingoid Grade 3 Cushingoid Severe symptoms, medical intervention or hospitalization indicated NCI Severe symptoms, medical intervention or hospitalization indicated CTCAE_v5 Grade 3 Cushingoid PT CTCAE_v5 Grade 3 Cushingoid, CTCAE PT NCI ctcae5:C145215 Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated Grade 3 Cystitis Noninfective, CTCAE Grade 3 Cystitis noninfective 10063057 C145215 Grade 3 Cystitis noninfective Grade 3 Cystitis noninfective Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated NCI Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Cystitis Noninfective, CTCAE PT NCI Grade 3 Cystitis noninfective PT CTCAE_v5 ctcae5:C145216 Hypotension managed with one pressor; hypoxia requiring >= 40% O2 Hypotension managed with one pressor; hypoxia requiring >= 40% O2 Grade 3 Cytokine Release Syndrome, CTCAE Grade 3 Cytokine release syndrome 10052015 C145216 Grade 3 Cytokine release syndrome Grade 3 Cytokine release syndrome Hypotension managed with one pressor; hypoxia requiring >= 40% O2 NCI Hypotension managed with one pressor; hypoxia requiring >= 40% O2 CTCAE_v5 Grade 3 Cytokine Release Syndrome, CTCAE PT NCI Grade 3 Cytokine release syndrome PT CTCAE_v5 ctcae5:C145217 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Grade 3 Cytomegalovirus Infection Reactivation, CTCAE Grade 3 Cytomegalovirus infection reactivation 10058666 C145217 Grade 3 Cytomegalovirus infection reactivation Grade 3 Cytomegalovirus infection reactivation Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated CTCAE_v5 Grade 3 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Grade 3 Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C145218 Severe and acute confusional state; limiting self care ADL; urgent intervention indicated; new onset Severe and acute confusional state; limiting self care ADL; urgent intervention indicated; new onset Grade 3 Delirium Grade 3 Delirium, CTCAE 10012218 C145218 Grade 3 Delirium Grade 3 Delirium Severe and acute confusional state; limiting self care ADL; urgent intervention indicated; new onset NCI Severe and acute confusional state; limiting self care ADL; urgent intervention indicated; new onset CTCAE_v5 Grade 3 Delirium PT CTCAE_v5 Grade 3 Delirium, CTCAE PT NCI ctcae5:C145219 Severe delusional symptoms; hospitalization not indicated; new onset Severe delusional symptoms; hospitalization not indicated; new onset Grade 3 Delusions Grade 3 Delusions, CTCAE 10012260 C145219 Grade 3 Delusions Grade 3 Delusions Severe delusional symptoms; hospitalization not indicated; new onset NCI Severe delusional symptoms; hospitalization not indicated; new onset CTCAE_v5 Grade 3 Delusions PT CTCAE_v5 Grade 3 Delusions, CTCAE PT NCI ctcae5:C145220 Dental caries resulting in pulpitis or periapical abscess or resulting in tooth loss Dental caries resulting in pulpitis or periapical abscess or resulting in tooth loss Grade 3 Dental Caries, CTCAE Grade 3 Dental caries 10012318 C145220 Grade 3 Dental caries Grade 3 Dental caries Dental caries resulting in pulpitis or periapical abscess or resulting in tooth loss NCI Dental caries resulting in pulpitis or periapical abscess or resulting in tooth loss CTCAE_v5 Grade 3 Dental Caries, CTCAE PT NCI Grade 3 Dental caries PT CTCAE_v5 ctcae5:C145221 Difficult to arouse Difficult to arouse Grade 3 Depressed Level of Consciousness, CTCAE Grade 3 Depressed level of consciousness 10012373 C145221 Grade 3 Depressed level of consciousness Grade 3 Depressed level of consciousness Difficult to arouse NCI Difficult to arouse CTCAE_v5 Grade 3 Depressed Level of Consciousness, CTCAE PT NCI Grade 3 Depressed level of consciousness PT CTCAE_v5 ctcae5:C145222 Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion Grade 3 Dermatitis Radiation, CTCAE Grade 3 Dermatitis radiation 10061103 C145222 Grade 3 Dermatitis radiation Grade 3 Dermatitis radiation Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion NCI Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion CTCAE_v5 Grade 3 Dermatitis Radiation, CTCAE PT NCI Grade 3 Dermatitis radiation PT CTCAE_v5 ctcae5:C145223 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Device Related Infection, CTCAE Grade 3 Device related infection 10064687 C145223 Grade 3 Device related infection Grade 3 Device related infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Device Related Infection, CTCAE PT NCI Grade 3 Device related infection PT CTCAE_v5 ctcae5:C145224 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Dry Eye, CTCAE Grade 3 Dry eye 10013774 C145224 Grade 3 Dry eye Grade 3 Dry eye Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Dry Eye, CTCAE PT NCI Grade 3 Dry eye PT CTCAE_v5 ctcae5:C145225 Inability to adequately aliment orally; tube feeding or TPN indicated; unstimulated saliva <0.1 ml/min Inability to adequately aliment orally; tube feeding or TPN indicated; unstimulated saliva <0.1 ml/min Grade 3 Dry Mouth, CTCAE Grade 3 Dry mouth 10013781 C145225 Grade 3 Dry mouth Grade 3 Dry mouth Inability to adequately aliment orally; tube feeding or TPN indicated; unstimulated saliva <0.1 ml/min NCI Inability to adequately aliment orally; tube feeding or TPN indicated; unstimulated saliva <0.1 ml/min CTCAE_v5 Grade 3 Dry Mouth, CTCAE PT NCI Grade 3 Dry mouth PT CTCAE_v5 ctcae5:C145227 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Duodenal Hemorrhage, CTCAE Grade 3 Duodenal hemorrhage 10055242 C145227 Grade 3 Duodenal hemorrhage Grade 3 Duodenal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Duodenal Hemorrhage, CTCAE PT NCI Grade 3 Duodenal hemorrhage PT CTCAE_v5 ctcae5:C145228 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Duodenal Infection, CTCAE Grade 3 Duodenal infection 10065752 C145228 Grade 3 Duodenal infection Grade 3 Duodenal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Duodenal Infection, CTCAE PT NCI Grade 3 Duodenal infection PT CTCAE_v5 ctcae5:C145229 Hospitalization indicated; invasive intervention indicated Hospitalization indicated; invasive intervention indicated Grade 3 Duodenal Obstruction, CTCAE Grade 3 Duodenal obstruction 10013830 C145229 Grade 3 Duodenal obstruction Grade 3 Duodenal obstruction Hospitalization indicated; invasive intervention indicated NCI Hospitalization indicated; invasive intervention indicated CTCAE_v5 Grade 3 Duodenal Obstruction, CTCAE PT NCI Grade 3 Duodenal obstruction PT CTCAE_v5 ctcae5:C145230 Invasive intervention indicated Invasive intervention indicated Grade 3 Duodenal Perforation, CTCAE Grade 3 Duodenal perforation 10013832 C145230 Grade 3 Duodenal perforation Grade 3 Duodenal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Duodenal Perforation, CTCAE PT NCI Grade 3 Duodenal perforation PT CTCAE_v5 ctcae5:C145231 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Duodenal Stenosis, CTCAE Grade 3 Duodenal stenosis 10050094 C145231 Grade 3 Duodenal stenosis Grade 3 Duodenal stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Duodenal Stenosis, CTCAE PT NCI Grade 3 Duodenal stenosis PT CTCAE_v5 ctcae5:C145232 Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Grade 3 Duodenal Ulcer, CTCAE Grade 3 Duodenal ulcer 10013836 C145232 Grade 3 Duodenal ulcer Grade 3 Duodenal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Duodenal Ulcer, CTCAE PT NCI Grade 3 Duodenal ulcer PT CTCAE_v5 ctcae5:C145233 Severe impairment of articulation or slurred speech Severe impairment of articulation or slurred speech Grade 3 Dysarthria Grade 3 Dysarthria, CTCAE 10013887 C145233 Grade 3 Dysarthria Grade 3 Dysarthria Severe impairment of articulation or slurred speech NCI Severe impairment of articulation or slurred speech CTCAE_v5 Grade 3 Dysarthria PT CTCAE_v5 Grade 3 Dysarthria, CTCAE PT NCI ctcae5:C145234 Severe sensory alteration; limiting self care ADL Severe sensory alteration; limiting self care ADL Grade 3 Dysesthesia Grade 3 Dysesthesia, CTCAE 10062872 C145234 Grade 3 Dysesthesia Grade 3 Dysesthesia Severe sensory alteration; limiting self care ADL NCI Severe sensory alteration; limiting self care ADL CTCAE_v5 Grade 3 Dysesthesia PT CTCAE_v5 Grade 3 Dysesthesia, CTCAE PT NCI ctcae5:C145235 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Dysmenorrhea Grade 3 Dysmenorrhea, CTCAE 10013934 C145235 Grade 3 Dysmenorrhea Grade 3 Dysmenorrhea Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Dysmenorrhea PT CTCAE_v5 Grade 3 Dysmenorrhea, CTCAE PT NCI ctcae5:C145236 Severe discomfort or pain associated with vaginal penetration; discomfort or pain unrelieved by vaginal lubricants or estrogen Severe discomfort or pain associated with vaginal penetration; discomfort or pain unrelieved by vaginal lubricants or estrogen Grade 3 Dyspareunia Grade 3 Dyspareunia, CTCAE 10013941 C145236 Grade 3 Dyspareunia Grade 3 Dyspareunia Severe discomfort or pain associated with vaginal penetration; discomfort or pain unrelieved by vaginal lubricants or estrogen NCI Severe discomfort or pain associated with vaginal penetration; discomfort or pain unrelieved by vaginal lubricants or estrogen CTCAE_v5 Grade 3 Dyspareunia PT CTCAE_v5 Grade 3 Dyspareunia, CTCAE PT NCI ctcae5:C145237 Severe symptoms; operative intervention indicated Severe symptoms; operative intervention indicated Grade 3 Dyspepsia Grade 3 Dyspepsia, CTCAE 10013946 C145237 Grade 3 Dyspepsia Grade 3 Dyspepsia Severe symptoms; operative intervention indicated NCI Severe symptoms; operative intervention indicated CTCAE_v5 Grade 3 Dyspepsia PT CTCAE_v5 Grade 3 Dyspepsia, CTCAE PT NCI ctcae5:C145238 Severe receptive or expressive characteristics; impairing ability to read, write or communicate intelligibly Severe receptive or expressive characteristics; impairing ability to read, write or communicate intelligibly Grade 3 Dysphasia Grade 3 Dysphasia, CTCAE 10013951 C145238 Grade 3 Dysphasia Grade 3 Dysphasia Severe receptive or expressive characteristics; impairing ability to read, write or communicate intelligibly NCI Severe receptive or expressive characteristics; impairing ability to read, write or communicate intelligibly CTCAE_v5 Grade 3 Dysphasia PT CTCAE_v5 Grade 3 Dysphasia, CTCAE PT NCI ctcae5:C145239 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Ear and Labyrinth Disorders - Other, Specify, CTCAE Grade 3 Ear and labyrinth disorders - Other, specify 10013993 C145239 Grade 3 Ear and labyrinth disorders - Other, specify Grade 3 Ear and labyrinth disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Grade 3 Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C145240 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Ear Pain, CTCAE Grade 3 Ear pain 10014020 C145240 Grade 3 Ear pain Grade 3 Ear pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Ear Pain, CTCAE PT NCI Grade 3 Ear pain PT CTCAE_v5 ctcae5:C145241 Severe or medically significant but not immediately life-threatening; IV intervention indicated Severe or medically significant but not immediately life-threatening; IV intervention indicated Grade 3 Eczema Grade 3 Eczema, CTCAE 10014184 C145241 Grade 3 Eczema Grade 3 Eczema Severe or medically significant but not immediately life-threatening; IV intervention indicated NCI Severe or medically significant but not immediately life-threatening; IV intervention indicated CTCAE_v5 Grade 3 Eczema PT CTCAE_v5 Grade 3 Eczema, CTCAE PT NCI ctcae5:C145242 New onset; worsening from baseline New onset; worsening from baseline Grade 3 Edema Cerebral, CTCAE Grade 3 Edema cerebral 10014217 C145242 Grade 3 Edema cerebral Grade 3 Edema cerebral New onset; worsening from baseline NCI New onset; worsening from baseline CTCAE_v5 Grade 3 Edema Cerebral, CTCAE PT NCI Grade 3 Edema cerebral PT CTCAE_v5 ctcae5:C145243 Severe swelling; limiting self care ADL Severe swelling; limiting self care ADL Grade 3 Edema Face, CTCAE Grade 3 Edema face 10014222 C145243 Grade 3 Edema face Grade 3 Edema face Severe swelling; limiting self care ADL NCI Severe swelling; limiting self care ADL CTCAE_v5 Grade 3 Edema Face, CTCAE PT NCI Grade 3 Edema face PT CTCAE_v5 ctcae5:C145244 >30% inter-limb discrepancy in volume; gross deviation from normal anatomic contour; limiting self care ADL >30% inter-limb discrepancy in volume; gross deviation from normal anatomic contour; limiting self care ADL Grade 3 Edema Limbs, CTCAE Grade 3 Edema limbs 10050068 C145244 Grade 3 Edema limbs Grade 3 Edema limbs >30% inter-limb discrepancy in volume; gross deviation from normal anatomic contour; limiting self care ADL NCI >30% inter-limb discrepancy in volume; gross deviation from normal anatomic contour; limiting self care ADL CTCAE_v5 Grade 3 Edema Limbs, CTCAE PT NCI Grade 3 Edema limbs PT CTCAE_v5 ctcae5:C145245 Gross deviation from normal anatomic contour; limiting self care ADL Gross deviation from normal anatomic contour; limiting self care ADL Grade 3 Edema Trunk, CTCAE Grade 3 Edema trunk 10058720 C145245 Grade 3 Edema trunk Grade 3 Edema trunk Gross deviation from normal anatomic contour; limiting self care ADL NCI Gross deviation from normal anatomic contour; limiting self care ADL CTCAE_v5 Grade 3 Edema Trunk, CTCAE PT NCI Grade 3 Edema trunk PT CTCAE_v5 ctcae5:C145246 Resting ejection fraction (EF) 39-20%; >=20% drop from baseline Resting ejection fraction (EF) 39-20%; >=20% drop from baseline Grade 3 Ejection Fraction Decreased, CTCAE Grade 3 Ejection fraction decreased 10050528 C145246 Grade 3 Ejection fraction decreased Grade 3 Ejection fraction decreased Resting ejection fraction (EF) 39-20%; >=20% drop from baseline NCI Resting ejection fraction (EF) 39-20%; >=20% drop from baseline CTCAE_v5 Grade 3 Ejection Fraction Decreased, CTCAE PT NCI Grade 3 Ejection fraction decreased PT CTCAE_v5 ctcae5:C145247 Average QTc >= 501 ms; >60 ms change from baseline Average QTc >= 501 ms; >60 ms change from baseline Grade 3 Electrocardiogram QT Corrected Interval Prolonged, CTCAE Grade 3 Electrocardiogram QT corrected interval prolonged 10014383 C145247 Grade 3 Electrocardiogram QT corrected interval prolonged Grade 3 Electrocardiogram QT corrected interval prolonged Average QTc >= 501 ms; >60 ms change from baseline NCI Average QTc >= 501 ms; >60 ms change from baseline CTCAE_v5 Grade 3 Electrocardiogram QT Corrected Interval Prolonged, CTCAE PT NCI Grade 3 Electrocardiogram QT corrected interval prolonged PT CTCAE_v5 ctcae5:C145248 IV antibiotic, antifungal, or antiviral intervention indicated; severe changes in mental status; self-limited seizure activity; focal neurologic abnormalities IV antibiotic, antifungal, or antiviral intervention indicated; severe changes in mental status; self-limited seizure activity; focal neurologic abnormalities Grade 3 Encephalitis Infection, CTCAE Grade 3 Encephalitis infection 10014594 C145248 Grade 3 Encephalitis infection Grade 3 Encephalitis infection IV antibiotic, antifungal, or antiviral intervention indicated; severe changes in mental status; self-limited seizure activity; focal neurologic abnormalities NCI IV antibiotic, antifungal, or antiviral intervention indicated; severe changes in mental status; self-limited seizure activity; focal neurologic abnormalities CTCAE_v5 Grade 3 Encephalitis Infection, CTCAE PT NCI Grade 3 Encephalitis infection PT CTCAE_v5 ctcae5:C145249 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Encephalomyelitis Infection, CTCAE Grade 3 Encephalomyelitis infection 10014621 C145249 Grade 3 Encephalomyelitis infection Grade 3 Encephalomyelitis infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Encephalomyelitis Infection, CTCAE PT NCI Grade 3 Encephalomyelitis infection PT CTCAE_v5 ctcae5:C145250 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Endocarditis Infective, CTCAE Grade 3 Endocarditis infective 10014678 C145250 Grade 3 Endocarditis infective Grade 3 Endocarditis infective IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Endocarditis Infective, CTCAE PT NCI Grade 3 Endocarditis infective PT CTCAE_v5 ctcae5:C145251 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Endocrine Disorders - Other, Specify, CTCAE Grade 3 Endocrine disorders - Other, specify 10014698 C145251 Grade 3 Endocrine disorders - Other, specify Grade 3 Endocrine disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Endocrine Disorders - Other, Specify, CTCAE PT NCI Grade 3 Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C145252 Systemic intervention; hospitalization indicated Systemic intervention; hospitalization indicated Grade 3 Endophthalmitis Grade 3 Endophthalmitis, CTCAE 10014801 C145252 Grade 3 Endophthalmitis Grade 3 Endophthalmitis Systemic intervention; hospitalization indicated NCI Systemic intervention; hospitalization indicated CTCAE_v5 Grade 3 Endophthalmitis PT CTCAE_v5 Grade 3 Endophthalmitis, CTCAE PT NCI ctcae5:C145253 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated Grade 3 Enterocolitis Infectious, CTCAE Grade 3 Enterocolitis infectious 10058838 C145253 Grade 3 Enterocolitis infectious Grade 3 Enterocolitis infectious IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; profuse watery diarrhea with signs of hypovolemia; bloody diarrhea; fever; severe abdominal pain; hospitalization indicated CTCAE_v5 Grade 3 Enterocolitis Infectious, CTCAE PT NCI Grade 3 Enterocolitis infectious PT CTCAE_v5 ctcae5:C145254 Severe or persistent abdominal pain; fever; ileus; peritoneal signs Severe or persistent abdominal pain; fever; ileus; peritoneal signs Grade 3 Enterocolitis Grade 3 Enterocolitis, CTCAE 10014893 C145254 Grade 3 Enterocolitis Grade 3 Enterocolitis Severe or persistent abdominal pain; fever; ileus; peritoneal signs NCI Severe or persistent abdominal pain; fever; ileus; peritoneal signs CTCAE_v5 Grade 3 Enterocolitis PT CTCAE_v5 Grade 3 Enterocolitis, CTCAE PT NCI ctcae5:C145255 Invasive intervention indicated Invasive intervention indicated Grade 3 Enterovesical Fistula, CTCAE Grade 3 Enterovesical fistula 10062570 C145255 Grade 3 Enterovesical fistula Grade 3 Enterovesical fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Enterovesical Fistula, CTCAE PT NCI Grade 3 Enterovesical fistula PT CTCAE_v5 ctcae5:C145256 Steroids initiated Steroids initiated Grade 3 Eosinophilia Grade 3 Eosinophilia, CTCAE 10014950 C145256 Grade 3 Eosinophilia Grade 3 Eosinophilia Steroids initiated NCI Steroids initiated CTCAE_v5 Grade 3 Eosinophilia PT CTCAE_v5 Grade 3 Eosinophilia, CTCAE PT NCI ctcae5:C145257 Transfusion; invasive intervention indicated (e.g., hemostasis of bleeding site) Transfusion; invasive intervention indicated (e.g., hemostasis of bleeding site) Grade 3 Epistaxis Grade 3 Epistaxis, CTCAE 10015090 C145257 Grade 3 Epistaxis Grade 3 Epistaxis Transfusion; invasive intervention indicated (e.g., hemostasis of bleeding site) NCI Transfusion; invasive intervention indicated (e.g., hemostasis of bleeding site) CTCAE_v5 Grade 3 Epistaxis PT CTCAE_v5 Grade 3 Epistaxis, CTCAE PT NCI ctcae5:C145258 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Grade 3 Epstein-Barr Virus Infection Reactivation, CTCAE Grade 3 Epstein-Barr virus infection reactivation 10015109 C145258 Grade 3 Epstein-Barr virus infection reactivation Grade 3 Epstein-Barr virus infection reactivation Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated CTCAE_v5 Grade 3 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Grade 3 Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C145259 Target lesions covering >30% BSA and associated with oral or genital erosions Target lesions covering >30% BSA and associated with oral or genital erosions Grade 3 Erythema Multiforme, CTCAE Grade 3 Erythema multiforme 10015218 C145259 Grade 3 Erythema multiforme Grade 3 Erythema multiforme Target lesions covering >30% BSA and associated with oral or genital erosions NCI Target lesions covering >30% BSA and associated with oral or genital erosions CTCAE_v5 Grade 3 Erythema Multiforme, CTCAE PT NCI Grade 3 Erythema multiforme PT CTCAE_v5 ctcae5:C145260 Erythema covering >90% BSA with associated symptoms (e.g., pruritus or tenderness); limiting self care ADL Erythema covering >90% BSA with associated symptoms (e.g., pruritus or tenderness); limiting self care ADL Grade 3 Erythroderma Grade 3 Erythroderma, CTCAE 10015277 C145260 Grade 3 Erythroderma Grade 3 Erythroderma Erythema covering >90% BSA with associated symptoms (e.g., pruritus or tenderness); limiting self care ADL NCI Erythema covering >90% BSA with associated symptoms (e.g., pruritus or tenderness); limiting self care ADL CTCAE_v5 Grade 3 Erythroderma PT CTCAE_v5 Grade 3 Erythroderma, CTCAE PT NCI ctcae5:C145261 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Esophageal Anastomotic Leak, CTCAE Grade 3 Esophageal anastomotic leak 10065961 C145261 Grade 3 Esophageal anastomotic leak Grade 3 Esophageal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Esophageal Anastomotic Leak, CTCAE PT NCI Grade 3 Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C145263 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Esophageal Hemorrhage, CTCAE Grade 3 Esophageal hemorrhage 10015384 C145263 Grade 3 Esophageal hemorrhage Grade 3 Esophageal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Esophageal Hemorrhage, CTCAE PT NCI Grade 3 Esophageal hemorrhage PT CTCAE_v5 ctcae5:C145264 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Esophageal Infection, CTCAE Grade 3 Esophageal infection 10058804 C145264 Grade 3 Esophageal infection Grade 3 Esophageal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Esophageal Infection, CTCAE PT NCI Grade 3 Esophageal infection PT CTCAE_v5 ctcae5:C145265 Inability to aliment adequately by GI tract; invasive intervention indicated Inability to aliment adequately by GI tract; invasive intervention indicated Grade 3 Esophageal Necrosis, CTCAE Grade 3 Esophageal necrosis 10065727 C145265 Grade 3 Esophageal necrosis Grade 3 Esophageal necrosis Inability to aliment adequately by GI tract; invasive intervention indicated NCI Inability to aliment adequately by GI tract; invasive intervention indicated CTCAE_v5 Grade 3 Esophageal Necrosis, CTCAE PT NCI Grade 3 Esophageal necrosis PT CTCAE_v5 ctcae5:C145266 Hospitalization indicated; invasive intervention indicated; limiting self care ADL Hospitalization indicated; invasive intervention indicated; limiting self care ADL Grade 3 Esophageal Obstruction, CTCAE Grade 3 Esophageal obstruction 10015387 C145266 Grade 3 Esophageal obstruction Grade 3 Esophageal obstruction Hospitalization indicated; invasive intervention indicated; limiting self care ADL NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Esophageal Obstruction, CTCAE PT NCI Grade 3 Esophageal obstruction PT CTCAE_v5 ctcae5:C145267 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Esophageal Pain, CTCAE Grade 3 Esophageal pain 10015388 C145267 Grade 3 Esophageal pain Grade 3 Esophageal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Esophageal Pain, CTCAE PT NCI Grade 3 Esophageal pain PT CTCAE_v5 ctcae5:C145268 Invasive intervention indicated Invasive intervention indicated Grade 3 Esophageal Perforation, CTCAE Grade 3 Esophageal perforation 10055472 C145268 Grade 3 Esophageal perforation Grade 3 Esophageal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Esophageal Perforation, CTCAE PT NCI Grade 3 Esophageal perforation PT CTCAE_v5 ctcae5:C145269 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Esophageal Stenosis, CTCAE Grade 3 Esophageal stenosis 10015448 C145269 Grade 3 Esophageal stenosis Grade 3 Esophageal stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Esophageal Stenosis, CTCAE PT NCI Grade 3 Esophageal stenosis PT CTCAE_v5 ctcae5:C145270 Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Grade 3 Esophageal Ulcer, CTCAE Grade 3 Esophageal ulcer 10015451 C145270 Grade 3 Esophageal ulcer Grade 3 Esophageal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Esophageal Ulcer, CTCAE PT NCI Grade 3 Esophageal ulcer PT CTCAE_v5 ctcae5:C145271 Bilateral paresis or unilateral paresis causing double vision in peripheral gaze, but not in central gaze Bilateral paresis or unilateral paresis causing double vision in peripheral gaze, but not in central gaze Grade 3 Extraocular Muscle Paresis, CTCAE Grade 3 Extraocular muscle paresis 10015829 C145271 Grade 3 Extraocular muscle paresis Grade 3 Extraocular muscle paresis Bilateral paresis or unilateral paresis causing double vision in peripheral gaze, but not in central gaze NCI Bilateral paresis or unilateral paresis causing double vision in peripheral gaze, but not in central gaze CTCAE_v5 Grade 3 Extraocular Muscle Paresis, CTCAE PT NCI Grade 3 Extraocular muscle paresis PT CTCAE_v5 ctcae5:C145272 Severe involuntary movements or torticollis; limiting self care ADL Severe involuntary movements or torticollis; limiting self care ADL Grade 3 Extrapyramidal Disorder, CTCAE Grade 3 Extrapyramidal disorder 10015832 C145272 Grade 3 Extrapyramidal disorder Grade 3 Extrapyramidal disorder Severe involuntary movements or torticollis; limiting self care ADL NCI Severe involuntary movements or torticollis; limiting self care ADL CTCAE_v5 Grade 3 Extrapyramidal Disorder, CTCAE PT NCI Grade 3 Extrapyramidal disorder PT CTCAE_v5 ctcae5:C145273 Severe or medically significant but not immediately sight-threatening; limiting self care ADL; decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Severe or medically significant but not immediately sight-threatening; limiting self care ADL; decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Grade 3 Eye Disorders - Other, Specify, CTCAE Grade 3 Eye disorders - Other, specify 10015919 C145273 Grade 3 Eye disorders - Other, specify Grade 3 Eye disorders - Other, specify Severe or medically significant but not immediately sight-threatening; limiting self care ADL; decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) NCI Severe or medically significant but not immediately sight-threatening; limiting self care ADL; decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) CTCAE_v5 Grade 3 Eye Disorders - Other, Specify, CTCAE PT NCI Grade 3 Eye disorders - Other, specify PT CTCAE_v5 ctcae5:C145274 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Eye Infection, CTCAE Grade 3 Eye infection 10015929 C145274 Grade 3 Eye infection Grade 3 Eye infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Eye Infection, CTCAE PT NCI Grade 3 Eye infection PT CTCAE_v5 ctcae5:C145275 Limiting self care ADL; operative intervention indicated Limiting self care ADL; operative intervention indicated Grade 3 Eyelid Function Disorder, CTCAE Grade 3 Eyelid function disorder 10061145 C145275 Grade 3 Eyelid function disorder Grade 3 Eyelid function disorder Limiting self care ADL; operative intervention indicated NCI Limiting self care ADL; operative intervention indicated CTCAE_v5 Grade 3 Eyelid Function Disorder, CTCAE PT NCI Grade 3 Eyelid function disorder PT CTCAE_v5 ctcae5:C145276 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Facial Muscle Weakness, CTCAE Grade 3 Facial muscle weakness 10051272 C145276 Grade 3 Facial muscle weakness Grade 3 Facial muscle weakness Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Facial Muscle Weakness, CTCAE PT NCI Grade 3 Facial muscle weakness PT CTCAE_v5 ctcae5:C145277 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Facial Nerve Disorder, CTCAE Grade 3 Facial nerve disorder 10061457 C145277 Grade 3 Facial nerve disorder Grade 3 Facial nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Facial Nerve Disorder, CTCAE PT NCI Grade 3 Facial nerve disorder PT CTCAE_v5 ctcae5:C145278 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Facial Pain, CTCAE Grade 3 Facial pain 10016059 C145278 Grade 3 Facial pain Grade 3 Facial pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Facial Pain, CTCAE PT NCI Grade 3 Facial pain PT CTCAE_v5 ctcae5:C145279 Hospitalization indicated; invasive intervention indicated Hospitalization indicated; invasive intervention indicated Grade 3 Fall Grade 3 Fall, CTCAE 10016173 C145279 Grade 3 Fall Grade 3 Fall Hospitalization indicated; invasive intervention indicated NCI Hospitalization indicated; invasive intervention indicated CTCAE_v5 Grade 3 Fall PT CTCAE_v5 Grade 3 Fall, CTCAE PT NCI ctcae5:C145280 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Fallopian Tube Anastomotic Leak, CTCAE Grade 3 Fallopian tube anastomotic leak 10065788 C145280 Grade 3 Fallopian tube anastomotic leak Grade 3 Fallopian tube anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Grade 3 Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C145281 Covering >30% BSA; associated with erythema or tenderness; limiting self-care ADL Covering >30% BSA; associated with erythema or tenderness; limiting self-care ADL Grade 3 Fat Atrophy, CTCAE Grade 3 Fat atrophy 10016241 C145281 Grade 3 Fat atrophy Grade 3 Fat atrophy Covering >30% BSA; associated with erythema or tenderness; limiting self-care ADL NCI Covering >30% BSA; associated with erythema or tenderness; limiting self-care ADL CTCAE_v5 Grade 3 Fat Atrophy, CTCAE PT NCI Grade 3 Fat atrophy PT CTCAE_v5 ctcae5:C145283 Severe symptoms; elective operative intervention indicated Severe symptoms; elective operative intervention indicated Grade 3 Fecal Incontinence, CTCAE Grade 3 Fecal incontinence 10016296 C145283 Grade 3 Fecal incontinence Grade 3 Fecal incontinence Severe symptoms; elective operative intervention indicated NCI Severe symptoms; elective operative intervention indicated CTCAE_v5 Grade 3 Fecal Incontinence, CTCAE PT NCI Grade 3 Fecal incontinence PT CTCAE_v5 ctcae5:C145284 <5% percentile of weight for gestational age <5% percentile of weight for gestational age Grade 3 Fetal Growth Retardation, CTCAE Grade 3 Fetal growth retardation 10054746 C145284 Grade 3 Fetal growth retardation Grade 3 Fetal growth retardation <5% percentile of weight for gestational age NCI <5% percentile of weight for gestational age CTCAE_v5 Grade 3 Fetal Growth Retardation, CTCAE PT NCI Grade 3 Fetal growth retardation PT CTCAE_v5 ctcae5:C145285 >40.0 degrees C (>104.0 degrees F) for <=24 hrs >40.0 degrees C (>104.0 degrees F) for <=24 hrs Grade 3 Fever Grade 3 Fever, CTCAE 10016558 C145285 Grade 3 Fever Grade 3 Fever >40.0 degrees C (>104.0 degrees F) for <=24 hrs NCI >40.0 degrees C (>104.0 degrees F) for <=24 hrs CTCAE_v5 Grade 3 Fever PT CTCAE_v5 Grade 3 Fever, CTCAE PT NCI ctcae5:C145286 <0.5-0.25 x LLN; if abnormal, 50-<75% decrease from baseline <0.5-0.25 x LLN; if abnormal, 50-<75% decrease from baseline Grade 3 Fibrinogen Decreased, CTCAE Grade 3 Fibrinogen decreased 10016596 C145286 Grade 3 Fibrinogen decreased Grade 3 Fibrinogen decreased <0.5-0.25 x LLN; if abnormal, 50-<75% decrease from baseline NCI <0.5-0.25 x LLN; if abnormal, 50-<75% decrease from baseline CTCAE_v5 Grade 3 Fibrinogen Decreased, CTCAE PT NCI Grade 3 Fibrinogen decreased PT CTCAE_v5 ctcae5:C145287 Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Grade 3 Fibrosis Deep Connective Tissue, CTCAE Grade 3 Fibrosis deep connective tissue 10065799 C145287 Grade 3 Fibrosis deep connective tissue Grade 3 Fibrosis deep connective tissue Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL NCI Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL CTCAE_v5 Grade 3 Fibrosis Deep Connective Tissue, CTCAE PT NCI Grade 3 Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C145288 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Flank Pain, CTCAE Grade 3 Flank pain 10016750 C145288 Grade 3 Flank pain Grade 3 Flank pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Flank Pain, CTCAE PT NCI Grade 3 Flank pain PT CTCAE_v5 ctcae5:C145289 Limiting self care ADL Limiting self care ADL Grade 3 Flashing Lights, CTCAE Grade 3 Flashing lights 10016757 C145289 Grade 3 Flashing lights Grade 3 Flashing lights Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Flashing Lights, CTCAE PT NCI Grade 3 Flashing lights PT CTCAE_v5 ctcae5:C145290 Limiting self care ADL Limiting self care ADL Grade 3 Floaters Grade 3 Floaters, CTCAE 10016778 C145290 Grade 3 Floaters Grade 3 Floaters Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Floaters PT CTCAE_v5 Grade 3 Floaters, CTCAE PT NCI ctcae5:C145291 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Flu Like Symptoms, CTCAE Grade 3 Flu like symptoms 10016791 C145291 Grade 3 Flu like symptoms Grade 3 Flu like symptoms Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Flu Like Symptoms, CTCAE PT NCI Grade 3 Flu like symptoms PT CTCAE_v5 ctcae5:C145292 Symptomatic, associated with hypotension and/or tachycardia; limiting self care ADL Symptomatic, associated with hypotension and/or tachycardia; limiting self care ADL Grade 3 Flushing Grade 3 Flushing, CTCAE 10016825 C145292 Grade 3 Flushing Grade 3 Flushing Symptomatic, associated with hypotension and/or tachycardia; limiting self care ADL NCI Symptomatic, associated with hypotension and/or tachycardia; limiting self care ADL CTCAE_v5 Grade 3 Flushing PT CTCAE_v5 Grade 3 Flushing, CTCAE PT NCI ctcae5:C145293 >30% BSA; systemic intervention indicated >30% BSA; systemic intervention indicated Grade 3 Folliculitis Grade 3 Folliculitis, CTCAE 10016936 C145293 Grade 3 Folliculitis Grade 3 Folliculitis >30% BSA; systemic intervention indicated NCI >30% BSA; systemic intervention indicated CTCAE_v5 Grade 3 Folliculitis PT CTCAE_v5 Grade 3 Folliculitis, CTCAE PT NCI ctcae5:C145294 50-59% 50-59% Grade 3 Forced Expiratory Volume Decreased, CTCAE Grade 3 Forced expiratory volume decreased 10016987 C145294 Grade 3 Forced expiratory volume decreased Grade 3 Forced expiratory volume decreased 50-59% NCI 50-59% CTCAE_v5 Grade 3 Forced Expiratory Volume Decreased, CTCAE PT NCI Grade 3 Forced expiratory volume decreased PT CTCAE_v5 ctcae5:C145295 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Grade 3 Fungemia Grade 3 Fungemia, CTCAE 10017544 C145295 Grade 3 Fungemia Grade 3 Fungemia Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated CTCAE_v5 Grade 3 Fungemia PT CTCAE_v5 Grade 3 Fungemia, CTCAE PT NCI ctcae5:C145296 Limiting self care ADL Limiting self care ADL Grade 3 Gait Disturbance, CTCAE Grade 3 Gait disturbance 10017577 C145296 Grade 3 Gait disturbance Grade 3 Gait disturbance Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Gait Disturbance, CTCAE PT NCI Grade 3 Gait disturbance PT CTCAE_v5 ctcae5:C145297 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Gallbladder Infection, CTCAE Grade 3 Gallbladder infection 10062632 C145297 Grade 3 Gallbladder infection Grade 3 Gallbladder infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Gallbladder Infection, CTCAE PT NCI Grade 3 Gallbladder infection PT CTCAE_v5 ctcae5:C145298 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Gastric Anastomotic Leak, CTCAE Grade 3 Gastric anastomotic leak 10065893 C145298 Grade 3 Gastric anastomotic leak Grade 3 Gastric anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Gastric Anastomotic Leak, CTCAE PT NCI Grade 3 Gastric anastomotic leak PT CTCAE_v5 ctcae5:C145299 Invasive intervention indicated Invasive intervention indicated Grade 3 Gastric Fistula, CTCAE Grade 3 Gastric fistula 10065713 C145299 Grade 3 Gastric fistula Grade 3 Gastric fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Gastric Fistula, CTCAE PT NCI Grade 3 Gastric fistula PT CTCAE_v5 ctcae5:C145300 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Gastric Hemorrhage, CTCAE Grade 3 Gastric hemorrhage 10017789 C145300 Grade 3 Gastric hemorrhage Grade 3 Gastric hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Gastric Hemorrhage, CTCAE PT NCI Grade 3 Gastric hemorrhage PT CTCAE_v5 ctcae5:C145301 Inability to aliment adequately by GI tract; invasive intervention indicated Inability to aliment adequately by GI tract; invasive intervention indicated Grade 3 Gastric Necrosis, CTCAE Grade 3 Gastric necrosis 10051886 C145301 Grade 3 Gastric necrosis Grade 3 Gastric necrosis Inability to aliment adequately by GI tract; invasive intervention indicated NCI Inability to aliment adequately by GI tract; invasive intervention indicated CTCAE_v5 Grade 3 Gastric Necrosis, CTCAE PT NCI Grade 3 Gastric necrosis PT CTCAE_v5 ctcae5:C145302 Invasive intervention indicated Invasive intervention indicated Grade 3 Gastric Perforation, CTCAE Grade 3 Gastric perforation 10017815 C145302 Grade 3 Gastric perforation Grade 3 Gastric perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Gastric Perforation, CTCAE PT NCI Grade 3 Gastric perforation PT CTCAE_v5 ctcae5:C145303 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Gastric Stenosis, CTCAE Grade 3 Gastric stenosis 10061970 C145303 Grade 3 Gastric stenosis Grade 3 Gastric stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Gastric Stenosis, CTCAE PT NCI Grade 3 Gastric stenosis PT CTCAE_v5 ctcae5:C145304 Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Grade 3 Gastric Ulcer, CTCAE Grade 3 Gastric ulcer 10017822 C145304 Grade 3 Gastric ulcer Grade 3 Gastric ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Gastric Ulcer, CTCAE PT NCI Grade 3 Gastric ulcer PT CTCAE_v5 ctcae5:C145305 Severe symptoms; operative intervention indicated Severe symptoms; operative intervention indicated Grade 3 Gastroesophageal Reflux Disease, CTCAE Grade 3 Gastroesophageal reflux disease 10066874 C145305 Grade 3 Gastroesophageal reflux disease Grade 3 Gastroesophageal reflux disease Severe symptoms; operative intervention indicated NCI Severe symptoms; operative intervention indicated CTCAE_v5 Grade 3 Gastroesophageal Reflux Disease, CTCAE PT NCI Grade 3 Gastroesophageal reflux disease PT CTCAE_v5 ctcae5:C145306 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Gastrointestinal Anastomotic Leak, CTCAE Grade 3 Gastrointestinal anastomotic leak 10065879 C145306 Grade 3 Gastrointestinal anastomotic leak Grade 3 Gastrointestinal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Grade 3 Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C145307 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Gastrointestinal Disorders - Other, Specify, CTCAE Grade 3 Gastrointestinal disorders - Other, specify 10017947 C145307 Grade 3 Gastrointestinal disorders - Other, specify Grade 3 Gastrointestinal disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Grade 3 Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C145308 Invasive intervention indicated Invasive intervention indicated Grade 3 Gastrointestinal Fistula, CTCAE Grade 3 Gastrointestinal fistula 10017877 C145308 Grade 3 Gastrointestinal fistula Grade 3 Gastrointestinal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Gastrointestinal Fistula, CTCAE PT NCI Grade 3 Gastrointestinal fistula PT CTCAE_v5 ctcae5:C145309 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Gastrointestinal Pain, CTCAE Grade 3 Gastrointestinal pain 10017999 C145309 Grade 3 Gastrointestinal pain Grade 3 Gastrointestinal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Gastrointestinal Pain, CTCAE PT NCI Grade 3 Gastrointestinal pain PT CTCAE_v5 ctcae5:C145310 Severe symptoms; hospitalization indicated; elective operative intervention indicated Severe symptoms; hospitalization indicated; elective operative intervention indicated Grade 3 Gastrointestinal Stoma Necrosis, CTCAE Grade 3 Gastrointestinal stoma necrosis 10065712 C145310 Grade 3 Gastrointestinal stoma necrosis Grade 3 Gastrointestinal stoma necrosis Severe symptoms; hospitalization indicated; elective operative intervention indicated NCI Severe symptoms; hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Gastrointestinal Stoma Necrosis, CTCAE PT NCI Grade 3 Gastrointestinal stoma necrosis PT CTCAE_v5 ctcae5:C145311 Weight loss >=20% from baseline; tube feeding or TPN indicated; elective operative intervention indicated Weight loss >=20% from baseline; tube feeding or TPN indicated; elective operative intervention indicated Grade 3 Gastroparesis Grade 3 Gastroparesis, CTCAE 10018043 C145311 Grade 3 Gastroparesis Grade 3 Gastroparesis Weight loss >=20% from baseline; tube feeding or TPN indicated; elective operative intervention indicated NCI Weight loss >=20% from baseline; tube feeding or TPN indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Gastroparesis PT CTCAE_v5 Grade 3 Gastroparesis, CTCAE PT NCI ctcae5:C145312 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 General Disorders and Administration Site Conditions - Other, Specify, CTCAE Grade 3 General disorders and administration site conditions - Other, specify 10018065 C145312 Grade 3 General disorders and administration site conditions - Other, specify Grade 3 General disorders and administration site conditions - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI Grade 3 General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C145313 Interferes with self care ADL; intravenous therapy indicated; skin breakdown Interferes with self care ADL; intravenous therapy indicated; skin breakdown Grade 3 Generalized Edema, CTCAE Grade 3 Generalized edema 10018112 C145313 Grade 3 Generalized edema Grade 3 Generalized edema Interferes with self care ADL; intravenous therapy indicated; skin breakdown NCI Interferes with self care ADL; intravenous therapy indicated; skin breakdown CTCAE_v5 Grade 3 Generalized Edema, CTCAE PT NCI Grade 3 Generalized edema PT CTCAE_v5 ctcae5:C145314 Limiting self care ADL Limiting self care ADL Grade 3 Generalized Muscle Weakness, CTCAE Grade 3 Generalized muscle weakness 10062572 C145314 Grade 3 Generalized muscle weakness Grade 3 Generalized muscle weakness Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Generalized Muscle Weakness, CTCAE PT NCI Grade 3 Generalized muscle weakness PT CTCAE_v5 ctcae5:C145315 Lymphorrhea; gross deviation from normal anatomic contour; limiting self care ADL Lymphorrhea; gross deviation from normal anatomic contour; limiting self care ADL Grade 3 Genital Edema, CTCAE Grade 3 Genital edema 10018146 C145315 Grade 3 Genital edema Grade 3 Genital edema Lymphorrhea; gross deviation from normal anatomic contour; limiting self care ADL NCI Lymphorrhea; gross deviation from normal anatomic contour; limiting self care ADL CTCAE_v5 Grade 3 Genital Edema, CTCAE PT NCI Grade 3 Genital edema PT CTCAE_v5 ctcae5:C145316 >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal Grade 3 GGT Increased, CTCAE Grade 3 GGT increased 10056910 C145316 Grade 3 GGT increased Grade 3 GGT increased >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal NCI >5.0-20.0 x ULN if baseline was normal; >5.0-20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 3 GGT Increased, CTCAE PT NCI Grade 3 GGT increased PT CTCAE_v5 ctcae5:C145317 Severe pain; inability to aliment orally Severe pain; inability to aliment orally Grade 3 Gingival Pain, CTCAE Grade 3 Gingival pain 10018286 C145317 Grade 3 Gingival pain Grade 3 Gingival pain Severe pain; inability to aliment orally NCI Severe pain; inability to aliment orally CTCAE_v5 Grade 3 Gingival Pain, CTCAE PT NCI Grade 3 Gingival pain PT CTCAE_v5 ctcae5:C145318 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Glossopharyngeal Nerve Disorder, CTCAE Grade 3 Glossopharyngeal nerve disorder 10061185 C145318 Grade 3 Glossopharyngeal nerve disorder Grade 3 Glossopharyngeal nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Grade 3 Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C145319 Severe symptoms; insulin indicated Severe symptoms; insulin indicated Grade 3 Glucose Intolerance, CTCAE Grade 3 Glucose intolerance 10052426 C145319 Grade 3 Glucose intolerance Grade 3 Glucose intolerance Severe symptoms; insulin indicated NCI Severe symptoms; insulin indicated CTCAE_v5 Grade 3 Glucose Intolerance, CTCAE PT NCI Grade 3 Glucose intolerance PT CTCAE_v5 ctcae5:C145320 Reduction in growth velocity of >=50% ideally measured over the period of a year Reduction in growth velocity of >=50% ideally measured over the period of a year Grade 3 Growth Suppression, CTCAE Grade 3 Growth suppression 10018761 C145320 Grade 3 Growth suppression Grade 3 Growth suppression Reduction in growth velocity of >=50% ideally measured over the period of a year NCI Reduction in growth velocity of >=50% ideally measured over the period of a year CTCAE_v5 Grade 3 Growth Suppression, CTCAE PT NCI Grade 3 Growth suppression PT CTCAE_v5 ctcae5:C145321 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Guillain-Barre Syndrome, CTCAE Grade 3 Guillain-Barre syndrome 10018767 C145321 Grade 3 Guillain-Barre syndrome Grade 3 Guillain-Barre syndrome Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Guillain-Barre Syndrome, CTCAE PT NCI Grade 3 Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C145322 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Gum Infection, CTCAE Grade 3 Gum infection 10018784 C145322 Grade 3 Gum infection Grade 3 Gum infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Gum Infection, CTCAE PT NCI Grade 3 Gum infection PT CTCAE_v5 ctcae5:C145323 Severe hallucinations; hospitalization not indicated Severe hallucinations; hospitalization not indicated Grade 3 Hallucinations Grade 3 Hallucinations, CTCAE 10019077 C145323 Grade 3 Hallucinations Grade 3 Hallucinations Severe hallucinations; hospitalization not indicated NCI Severe hallucinations; hospitalization not indicated CTCAE_v5 Grade 3 Hallucinations PT CTCAE_v5 Grade 3 Hallucinations, CTCAE PT NCI ctcae5:C145324 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Headache Grade 3 Headache, CTCAE 10019211 C145324 Grade 3 Headache Grade 3 Headache Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Headache PT CTCAE_v5 Grade 3 Headache, CTCAE PT NCI ctcae5:C145325 Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 3 contiguous test frequencies in at least one ear; therapeutic intervention indicated; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention indicated; limiting self care ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Hearing loss sufficient to indicate therapeutic intervention, including hearing aids; threshold shift >20 dB at 2 to < 4 kHz in at least one ear Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 3 contiguous test frequencies in at least one ear; therapeutic intervention indicated; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention indicated; limiting self care ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Hearing loss sufficient to indicate therapeutic intervention, including hearing aids; threshold shift >20 dB at 2 to < 4 kHz in at least one ear Grade 3 Hearing Impaired, CTCAE Grade 3 Hearing impaired 10019245 C145325 Grade 3 Hearing impaired Grade 3 Hearing impaired Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 3 contiguous test frequencies in at least one ear; therapeutic intervention indicated; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention indicated; limiting self care ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Hearing loss sufficient to indicate therapeutic intervention, including hearing aids; threshold shift >20 dB at 2 to < 4 kHz in at least one ear NCI Adults enrolled on a Monitoring Program (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Threshold shift of >25 dB averaged at 3 contiguous test frequencies in at least one ear; therapeutic intervention indicated; Adults not enrolled on a Monitoring Program: Hearing loss with hearing aid or intervention indicated; limiting self care ADL; Pediatric (on a 1, 2, 3, 4, 6, and 8 kHz audiogram): Hearing loss sufficient to indicate therapeutic intervention, including hearing aids; threshold shift >20 dB at 2 to < 4 kHz in at least one ear CTCAE_v5 Grade 3 Hearing Impaired, CTCAE PT NCI Grade 3 Hearing impaired PT CTCAE_v5 ctcae5:C145326 Symptoms at rest or with minimal activity or exertion; hospitalization; new onset of symptoms Symptoms at rest or with minimal activity or exertion; hospitalization; new onset of symptoms Grade 3 Heart Failure, CTCAE Grade 3 Heart failure 10019279 C145326 Grade 3 Heart failure Grade 3 Heart failure Symptoms at rest or with minimal activity or exertion; hospitalization; new onset of symptoms NCI Symptoms at rest or with minimal activity or exertion; hospitalization; new onset of symptoms CTCAE_v5 Grade 3 Heart Failure, CTCAE PT NCI Grade 3 Heart failure PT CTCAE_v5 ctcae5:C145327 Transfusion indicated; invasive intervention indicated Transfusion indicated; invasive intervention indicated Grade 3 Hematosalpinx Grade 3 Hematosalpinx, CTCAE 10060602 C145327 Grade 3 Hematosalpinx Grade 3 Hematosalpinx Transfusion indicated; invasive intervention indicated NCI Transfusion indicated; invasive intervention indicated CTCAE_v5 Grade 3 Hematosalpinx PT CTCAE_v5 Grade 3 Hematosalpinx, CTCAE PT NCI ctcae5:C145328 Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated; limiting self care ADL Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated; limiting self care ADL Grade 3 Hematuria Grade 3 Hematuria, CTCAE 10019450 C145328 Grade 3 Hematuria Grade 3 Hematuria Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated; limiting self care ADL NCI Gross hematuria; transfusion, IV medications, or hospitalization indicated; elective invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Hematuria PT CTCAE_v5 Grade 3 Hematuria, CTCAE PT NCI ctcae5:C145329 Increase in >4 g/dL Increase in >4 g/dL Grade 3 Hemoglobin Increased, CTCAE Grade 3 Hemoglobin increased 10055599 C145329 Grade 3 Hemoglobin increased Grade 3 Hemoglobin increased Increase in >4 g/dL NCI Increase in >4 g/dL CTCAE_v5 Grade 3 Hemoglobin Increased, CTCAE PT NCI Grade 3 Hemoglobin increased PT CTCAE_v5 ctcae5:C145330 Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) Grade 3 Hemolytic Uremic Syndrome, CTCAE Grade 3 Hemolytic uremic syndrome 10019515 C145330 Grade 3 Hemolytic uremic syndrome Grade 3 Hemolytic uremic syndrome Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) NCI Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) CTCAE_v5 Grade 3 Hemolytic Uremic Syndrome, CTCAE PT NCI Grade 3 Hemolytic uremic syndrome PT CTCAE_v5 ctcae5:C145331 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Hemorrhoidal Hemorrhage, CTCAE Grade 3 Hemorrhoidal hemorrhage 10060640 C145331 Grade 3 Hemorrhoidal hemorrhage Grade 3 Hemorrhoidal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Hemorrhoidal Hemorrhage, CTCAE PT NCI Grade 3 Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C145332 Asterixis; mild encephalopathy; drug-induced liver injury (DILI); limiting self care ADL Asterixis; mild encephalopathy; drug-induced liver injury (DILI); limiting self care ADL Grade 3 Hepatic Failure, CTCAE Grade 3 Hepatic failure 10019663 C145332 Grade 3 Hepatic failure Grade 3 Hepatic failure Asterixis; mild encephalopathy; drug-induced liver injury (DILI); limiting self care ADL NCI Asterixis; mild encephalopathy; drug-induced liver injury (DILI); limiting self care ADL CTCAE_v5 Grade 3 Hepatic Failure, CTCAE PT NCI Grade 3 Hepatic failure PT CTCAE_v5 ctcae5:C145333 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Hepatic Hemorrhage, CTCAE Grade 3 Hepatic hemorrhage 10019678 C145333 Grade 3 Hepatic hemorrhage Grade 3 Hepatic hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Hepatic Hemorrhage, CTCAE PT NCI Grade 3 Hepatic hemorrhage PT CTCAE_v5 ctcae5:C145334 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Hepatic Infection, CTCAE Grade 3 Hepatic infection 10056522 C145334 Grade 3 Hepatic infection Grade 3 Hepatic infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Hepatic Infection, CTCAE PT NCI Grade 3 Hepatic infection PT CTCAE_v5 ctcae5:C145335 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Hepatic Pain, CTCAE Grade 3 Hepatic pain 10019705 C145335 Grade 3 Hepatic pain Grade 3 Hepatic pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Hepatic Pain, CTCAE PT NCI Grade 3 Hepatic pain PT CTCAE_v5 ctcae5:C145336 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Grade 3 Hepatitis B Reactivation, CTCAE Grade 3 Hepatitis B reactivation 10058827 C145336 Grade 3 Hepatitis B reactivation Grade 3 Hepatitis B reactivation Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated CTCAE_v5 Grade 3 Hepatitis B Reactivation, CTCAE PT NCI Grade 3 Hepatitis B reactivation PT CTCAE_v5 ctcae5:C145337 Symptomatic liver dysfunction; fibrosis by biopsy; compensated cirrhosis; hospitalization or prolongation of existing hospitalization indicated Symptomatic liver dysfunction; fibrosis by biopsy; compensated cirrhosis; hospitalization or prolongation of existing hospitalization indicated Grade 3 Hepatitis Viral, CTCAE Grade 3 Hepatitis viral 10019799 C145337 Grade 3 Hepatitis viral Grade 3 Hepatitis viral Symptomatic liver dysfunction; fibrosis by biopsy; compensated cirrhosis; hospitalization or prolongation of existing hospitalization indicated NCI Symptomatic liver dysfunction; fibrosis by biopsy; compensated cirrhosis; hospitalization or prolongation of existing hospitalization indicated CTCAE_v5 Grade 3 Hepatitis Viral, CTCAE PT NCI Grade 3 Hepatitis viral PT CTCAE_v5 ctcae5:C145338 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Hepatobiliary Disorders - Other, Specify, CTCAE Grade 3 Hepatobiliary disorders - Other, specify 10019805 C145338 Grade 3 Hepatobiliary disorders - Other, specify Grade 3 Hepatobiliary disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Grade 3 Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C145339 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated Grade 3 Herpes Simplex Reactivation, CTCAE Grade 3 Herpes simplex reactivation 10080137 C145339 Grade 3 Herpes simplex reactivation Grade 3 Herpes simplex reactivation Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated CTCAE_v5 Grade 3 Herpes Simplex Reactivation, CTCAE PT NCI Grade 3 Herpes simplex reactivation PT CTCAE_v5 ctcae5:C145340 Severe symptoms; interfering with sleep; limiting self care ADL Severe symptoms; interfering with sleep; limiting self care ADL Grade 3 Hiccups Grade 3 Hiccups, CTCAE 10020039 C145340 Grade 3 Hiccups Grade 3 Hiccups Severe symptoms; interfering with sleep; limiting self care ADL NCI Severe symptoms; interfering with sleep; limiting self care ADL CTCAE_v5 Grade 3 Hiccups PT CTCAE_v5 Grade 3 Hiccups, CTCAE PT NCI ctcae5:C145341 Severe pain; hospitalization or intervention indicated for pain control (e.g., traction); operative intervention indicated Severe pain; hospitalization or intervention indicated for pain control (e.g., traction); operative intervention indicated Grade 3 Hip Fracture, CTCAE Grade 3 Hip fracture 10020100 C145341 Grade 3 Hip fracture Grade 3 Hip fracture Severe pain; hospitalization or intervention indicated for pain control (e.g., traction); operative intervention indicated NCI Severe pain; hospitalization or intervention indicated for pain control (e.g., traction); operative intervention indicated CTCAE_v5 Grade 3 Hip Fracture, CTCAE PT NCI Grade 3 Hip fracture PT CTCAE_v5 ctcae5:C145342 Severe voice changes including predominantly whispered speech Severe voice changes including predominantly whispered speech Grade 3 Hoarseness Grade 3 Hoarseness, CTCAE 10020201 C145342 Grade 3 Hoarseness Grade 3 Hoarseness Severe voice changes including predominantly whispered speech NCI Severe voice changes including predominantly whispered speech CTCAE_v5 Grade 3 Hoarseness PT CTCAE_v5 Grade 3 Hoarseness, CTCAE PT NCI ctcae5:C145343 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Hot Flashes, CTCAE Grade 3 Hot flashes 10020407 C145343 Grade 3 Hot flashes Grade 3 Hot flashes Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Hot Flashes, CTCAE PT NCI Grade 3 Hot flashes PT CTCAE_v5 ctcae5:C145344 Corrected serum calcium of >12.5-13.5 mg/dL; >3.1-3.4 mmol/L; Ionized calcium >1.6-1.8 mmol/L; hospitalization indicated Corrected serum calcium of >12.5-13.5 mg/dL; >3.1-3.4 mmol/L; Ionized calcium >1.6-1.8 mmol/L; hospitalization indicated Grade 3 Hypercalcemia Grade 3 Hypercalcemia, CTCAE 10020587 C145344 Grade 3 Hypercalcemia Grade 3 Hypercalcemia Corrected serum calcium of >12.5-13.5 mg/dL; >3.1-3.4 mmol/L; Ionized calcium >1.6-1.8 mmol/L; hospitalization indicated NCI Corrected serum calcium of >12.5-13.5 mg/dL; >3.1-3.4 mmol/L; Ionized calcium >1.6-1.8 mmol/L; hospitalization indicated CTCAE_v5 Grade 3 Hypercalcemia PT CTCAE_v5 Grade 3 Hypercalcemia, CTCAE PT NCI ctcae5:C145345 Insulin therapy initiated; hospitalization indicated Insulin therapy initiated; hospitalization indicated Grade 3 Hyperglycemia Grade 3 Hyperglycemia, CTCAE 10020639 C145345 Grade 3 Hyperglycemia Grade 3 Hyperglycemia Insulin therapy initiated; hospitalization indicated NCI Insulin therapy initiated; hospitalization indicated CTCAE_v5 Grade 3 Hyperglycemia PT CTCAE_v5 Grade 3 Hyperglycemia, CTCAE PT NCI ctcae5:C145346 Associated with electrolyte/hemodynamic imbalance Associated with electrolyte/hemodynamic imbalance Grade 3 Hyperhidrosis Grade 3 Hyperhidrosis, CTCAE 10020642 C145346 Grade 3 Hyperhidrosis Grade 3 Hyperhidrosis Associated with electrolyte/hemodynamic imbalance NCI Associated with electrolyte/hemodynamic imbalance CTCAE_v5 Grade 3 Hyperhidrosis PT CTCAE_v5 Grade 3 Hyperhidrosis, CTCAE PT NCI ctcae5:C145347 >6.0-7.0 mmol/L; hospitalization indicated >6.0-7.0 mmol/L; hospitalization indicated Grade 3 Hyperkalemia Grade 3 Hyperkalemia, CTCAE 10020647 C145347 Grade 3 Hyperkalemia Grade 3 Hyperkalemia >6.0-7.0 mmol/L; hospitalization indicated NCI >6.0-7.0 mmol/L; hospitalization indicated CTCAE_v5 Grade 3 Hyperkalemia PT CTCAE_v5 Grade 3 Hyperkalemia, CTCAE PT NCI ctcae5:C145348 Limiting self-care ADLs Limiting self-care ADLs Grade 3 Hyperkeratosis Grade 3 Hyperkeratosis, CTCAE 10020649 C145348 Grade 3 Hyperkeratosis Grade 3 Hyperkeratosis Limiting self-care ADLs NCI Limiting self-care ADLs CTCAE_v5 Grade 3 Hyperkeratosis PT CTCAE_v5 Grade 3 Hyperkeratosis, CTCAE PT NCI ctcae5:C145349 Hospitalization; pancreatitis Hospitalization; pancreatitis Grade 3 Hyperlipidemia Grade 3 Hyperlipidemia, CTCAE 10020667 C145349 Grade 3 Hyperlipidemia Grade 3 Hyperlipidemia Hospitalization; pancreatitis NCI Hospitalization; pancreatitis CTCAE_v5 Grade 3 Hyperlipidemia PT CTCAE_v5 Grade 3 Hyperlipidemia, CTCAE PT NCI ctcae5:C145350 >3.0-8.0 mg/dL; >1.23-3.30 mmol/L >3.0-8.0 mg/dL; >1.23-3.30 mmol/L Grade 3 Hypermagnesemia Grade 3 Hypermagnesemia, CTCAE 10020670 C145350 Grade 3 Hypermagnesemia Grade 3 Hypermagnesemia >3.0-8.0 mg/dL; >1.23-3.30 mmol/L NCI >3.0-8.0 mg/dL; >1.23-3.30 mmol/L CTCAE_v5 Grade 3 Hypermagnesemia PT CTCAE_v5 Grade 3 Hypermagnesemia, CTCAE PT NCI ctcae5:C145351 >155-160 mmol/L; hospitalization indicated >155-160 mmol/L; hospitalization indicated Grade 3 Hypernatremia Grade 3 Hypernatremia, CTCAE 10020680 C145351 Grade 3 Hypernatremia Grade 3 Hypernatremia >155-160 mmol/L; hospitalization indicated NCI >155-160 mmol/L; hospitalization indicated CTCAE_v5 Grade 3 Hypernatremia PT CTCAE_v5 Grade 3 Hypernatremia, CTCAE PT NCI ctcae5:C145352 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Grade 3 Hyperphosphatemia Grade 3 Hyperphosphatemia, CTCAE 10020712 C145352 Grade 3 Hyperphosphatemia Grade 3 Hyperphosphatemia Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated CTCAE_v5 Grade 3 Hyperphosphatemia PT CTCAE_v5 Grade 3 Hyperphosphatemia, CTCAE PT NCI ctcae5:C145353 Severe increased need for sleep Severe increased need for sleep Grade 3 Hypersomnia Grade 3 Hypersomnia, CTCAE 10020765 C145353 Grade 3 Hypersomnia Grade 3 Hypersomnia Severe increased need for sleep NCI Severe increased need for sleep CTCAE_v5 Grade 3 Hypersomnia PT CTCAE_v5 Grade 3 Hypersomnia, CTCAE PT NCI ctcae5:C145354 Severe symptoms; limiting self care ADL; hospitalization indicated Severe symptoms; limiting self care ADL; hospitalization indicated Grade 3 Hyperthyroidism Grade 3 Hyperthyroidism, CTCAE 10020850 C145354 Grade 3 Hyperthyroidism Grade 3 Hyperthyroidism Severe symptoms; limiting self care ADL; hospitalization indicated NCI Severe symptoms; limiting self care ADL; hospitalization indicated CTCAE_v5 Grade 3 Hyperthyroidism PT CTCAE_v5 Grade 3 Hyperthyroidism, CTCAE PT NCI ctcae5:C145355 >500 mg/dL-1000 mg/dL; >5.7 mmol/L-11.4 mmol/L >500 mg/dL-1000 mg/dL; >5.7 mmol/L-11.4 mmol/L Grade 3 Hypertriglyceridemia Grade 3 Hypertriglyceridemia, CTCAE 10020870 C145355 Grade 3 Hypertriglyceridemia Grade 3 Hypertriglyceridemia >500 mg/dL-1000 mg/dL; >5.7 mmol/L-11.4 mmol/L NCI >500 mg/dL-1000 mg/dL; >5.7 mmol/L-11.4 mmol/L CTCAE_v5 Grade 3 Hypertriglyceridemia PT CTCAE_v5 Grade 3 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C145356 >ULN with physiologic consequences >ULN with physiologic consequences Grade 3 Hyperuricemia Grade 3 Hyperuricemia, CTCAE 10020907 C145356 Grade 3 Hyperuricemia Grade 3 Hyperuricemia >ULN with physiologic consequences NCI >ULN with physiologic consequences CTCAE_v5 Grade 3 Hyperuricemia PT CTCAE_v5 Grade 3 Hyperuricemia, CTCAE PT NCI ctcae5:C145357 <2 g/dL; <20 g/L <2 g/dL; <20 g/L Grade 3 Hypoalbuminemia Grade 3 Hypoalbuminemia, CTCAE 10020943 C145357 Grade 3 Hypoalbuminemia Grade 3 Hypoalbuminemia <2 g/dL; <20 g/L NCI <2 g/dL; <20 g/L CTCAE_v5 Grade 3 Hypoalbuminemia PT CTCAE_v5 Grade 3 Hypoalbuminemia, CTCAE PT NCI ctcae5:C145358 Corrected serum calcium of <7.0-6.0 mg/dL; <1.75-1.5 mmol/L; Ionized calcium <0.9-0.8 mmol/L; hospitalization indicated Corrected serum calcium of <7.0-6.0 mg/dL; <1.75-1.5 mmol/L; Ionized calcium <0.9-0.8 mmol/L; hospitalization indicated Grade 3 Hypocalcemia Grade 3 Hypocalcemia, CTCAE 10020949 C145358 Grade 3 Hypocalcemia Grade 3 Hypocalcemia Corrected serum calcium of <7.0-6.0 mg/dL; <1.75-1.5 mmol/L; Ionized calcium <0.9-0.8 mmol/L; hospitalization indicated NCI Corrected serum calcium of <7.0-6.0 mg/dL; <1.75-1.5 mmol/L; Ionized calcium <0.9-0.8 mmol/L; hospitalization indicated CTCAE_v5 Grade 3 Hypocalcemia PT CTCAE_v5 Grade 3 Hypocalcemia, CTCAE PT NCI ctcae5:C145359 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Hypoglossal Nerve Disorder, CTCAE Grade 3 Hypoglossal nerve disorder 10061212 C145359 Grade 3 Hypoglossal nerve disorder Grade 3 Hypoglossal nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Hypoglossal Nerve Disorder, CTCAE PT NCI Grade 3 Hypoglossal nerve disorder PT CTCAE_v5 ctcae5:C145360 <40-30 mg/dL; <2.2-1.7 mmol/L <40-30 mg/dL; <2.2-1.7 mmol/L Grade 3 Hypoglycemia Grade 3 Hypoglycemia, CTCAE 10021005 C145360 Grade 3 Hypoglycemia Grade 3 Hypoglycemia <40-30 mg/dL; <2.2-1.7 mmol/L NCI <40-30 mg/dL; <2.2-1.7 mmol/L CTCAE_v5 Grade 3 Hypoglycemia PT CTCAE_v5 Grade 3 Hypoglycemia, CTCAE PT NCI ctcae5:C145361 Increase in body temperature; limiting self care ADL Increase in body temperature; limiting self care ADL Grade 3 Hypohidrosis Grade 3 Hypohidrosis, CTCAE 10021013 C145361 Grade 3 Hypohidrosis Grade 3 Hypohidrosis Increase in body temperature; limiting self care ADL NCI Increase in body temperature; limiting self care ADL CTCAE_v5 Grade 3 Hypohidrosis PT CTCAE_v5 Grade 3 Hypohidrosis, CTCAE PT NCI ctcae5:C145362 <3.0-2.5 mmol/L; hospitalization indicated <3.0-2.5 mmol/L; hospitalization indicated Grade 3 Hypokalemia Grade 3 Hypokalemia, CTCAE 10021018 C145362 Grade 3 Hypokalemia Grade 3 Hypokalemia <3.0-2.5 mmol/L; hospitalization indicated NCI <3.0-2.5 mmol/L; hospitalization indicated CTCAE_v5 Grade 3 Hypokalemia PT CTCAE_v5 Grade 3 Hypokalemia, CTCAE PT NCI ctcae5:C145363 <0.9-0.7 mg/dL; <0.4-0.3 mmol/L <0.9-0.7 mg/dL; <0.4-0.3 mmol/L Grade 3 Hypomagnesemia Grade 3 Hypomagnesemia, CTCAE 10021028 C145363 Grade 3 Hypomagnesemia Grade 3 Hypomagnesemia <0.9-0.7 mg/dL; <0.4-0.3 mmol/L NCI <0.9-0.7 mg/dL; <0.4-0.3 mmol/L CTCAE_v5 Grade 3 Hypomagnesemia PT CTCAE_v5 Grade 3 Hypomagnesemia, CTCAE PT NCI ctcae5:C145364 125-129 mmol/L symptomatic; 120-124 mmol/L regardless of symptoms 125-129 mmol/L symptomatic; 120-124 mmol/L regardless of symptoms Grade 3 Hyponatremia Grade 3 Hyponatremia, CTCAE 10021038 C145364 Grade 3 Hyponatremia Grade 3 Hyponatremia 125-129 mmol/L symptomatic; 120-124 mmol/L regardless of symptoms NCI 125-129 mmol/L symptomatic; 120-124 mmol/L regardless of symptoms CTCAE_v5 Grade 3 Hyponatremia PT CTCAE_v5 Grade 3 Hyponatremia, CTCAE PT NCI ctcae5:C145365 Severe symptoms; medical intervention or hospitalization indicated Severe symptoms; medical intervention or hospitalization indicated Grade 3 Hypoparathyroidism Grade 3 Hypoparathyroidism, CTCAE 10021041 C145365 Grade 3 Hypoparathyroidism Grade 3 Hypoparathyroidism Severe symptoms; medical intervention or hospitalization indicated NCI Severe symptoms; medical intervention or hospitalization indicated CTCAE_v5 Grade 3 Hypoparathyroidism PT CTCAE_v5 Grade 3 Hypoparathyroidism, CTCAE PT NCI ctcae5:C145366 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Grade 3 Hypophosphatemia Grade 3 Hypophosphatemia, CTCAE 10021059 C145366 Grade 3 Hypophosphatemia Grade 3 Hypophosphatemia Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated CTCAE_v5 Grade 3 Hypophosphatemia PT CTCAE_v5 Grade 3 Hypophosphatemia, CTCAE PT NCI ctcae5:C145367 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Hypophysitis Grade 3 Hypophysitis, CTCAE 10062767 C145367 Grade 3 Hypophysitis Grade 3 Hypophysitis Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Hypophysitis PT CTCAE_v5 Grade 3 Hypophysitis, CTCAE PT NCI ctcae5:C145368 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Hypopituitarism Grade 3 Hypopituitarism, CTCAE 10021067 C145368 Grade 3 Hypopituitarism Grade 3 Hypopituitarism Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Hypopituitarism PT CTCAE_v5 Grade 3 Hypopituitarism, CTCAE PT NCI ctcae5:C145369 Severe symptoms; limiting self care ADL; hospitalization indicated Severe symptoms; limiting self care ADL; hospitalization indicated Grade 3 Hypothyroidism Grade 3 Hypothyroidism, CTCAE 10021114 C145369 Grade 3 Hypothyroidism Grade 3 Hypothyroidism Severe symptoms; limiting self care ADL; hospitalization indicated NCI Severe symptoms; limiting self care ADL; hospitalization indicated CTCAE_v5 Grade 3 Hypothyroidism PT CTCAE_v5 Grade 3 Hypothyroidism, CTCAE PT NCI ctcae5:C145373 Invasive intervention indicated Invasive intervention indicated Grade 3 Ileal Perforation, CTCAE Grade 3 Ileal perforation 10021305 C145373 Grade 3 Ileal perforation Grade 3 Ileal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Ileal Perforation, CTCAE PT NCI Grade 3 Ileal perforation PT CTCAE_v5 ctcae5:C145374 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Ileal Stenosis, CTCAE Grade 3 Ileal stenosis 10021307 C145374 Grade 3 Ileal stenosis Grade 3 Ileal stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Ileal Stenosis, CTCAE PT NCI Grade 3 Ileal stenosis PT CTCAE_v5 ctcae5:C145377 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Immune System Disorders - Other, Specify, CTCAE Grade 3 Immune system disorders - Other, specify 10021428 C145377 Grade 3 Immune system disorders - Other, specify Grade 3 Immune system disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Immune System Disorders - Other, Specify, CTCAE PT NCI Grade 3 Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C145378 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Infections and Infestations - Other, Specify, CTCAE Grade 3 Infections and infestations - Other, specify 10021881 C145378 Grade 3 Infections and infestations - Other, specify Grade 3 Infections and infestations - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Infections and Infestations - Other, Specify, CTCAE PT NCI Grade 3 Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C145379 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Infective Myositis, CTCAE Grade 3 Infective myositis 10021918 C145379 Grade 3 Infective myositis Grade 3 Infective myositis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Infective Myositis, CTCAE PT NCI Grade 3 Infective myositis PT CTCAE_v5 ctcae5:C145380 Prolonged (e.g., not rapidly responsive to symptomatic medication and/or brief interruption of infusion); recurrence of symptoms following initial improvement; hospitalization indicated for clinical sequelae Prolonged (e.g., not rapidly responsive to symptomatic medication and/or brief interruption of infusion); recurrence of symptoms following initial improvement; hospitalization indicated for clinical sequelae Grade 3 Infusion Related Reaction, CTCAE Grade 3 Infusion related reaction 10051792 C145380 Grade 3 Infusion related reaction Grade 3 Infusion related reaction Prolonged (e.g., not rapidly responsive to symptomatic medication and/or brief interruption of infusion); recurrence of symptoms following initial improvement; hospitalization indicated for clinical sequelae NCI Prolonged (e.g., not rapidly responsive to symptomatic medication and/or brief interruption of infusion); recurrence of symptoms following initial improvement; hospitalization indicated for clinical sequelae CTCAE_v5 Grade 3 Infusion Related Reaction, CTCAE PT NCI Grade 3 Infusion related reaction PT CTCAE_v5 ctcae5:C145381 Ulceration or necrosis; severe tissue damage; operative intervention indicated Ulceration or necrosis; severe tissue damage; operative intervention indicated Grade 3 Infusion Site Extravasation, CTCAE Grade 3 Infusion site extravasation 10064774 C145381 Grade 3 Infusion site extravasation Grade 3 Infusion site extravasation Ulceration or necrosis; severe tissue damage; operative intervention indicated NCI Ulceration or necrosis; severe tissue damage; operative intervention indicated CTCAE_v5 Grade 3 Infusion Site Extravasation, CTCAE PT NCI Grade 3 Infusion site extravasation PT CTCAE_v5 ctcae5:C145382 Ulceration or necrosis; severe tissue damage; operative intervention indicated Ulceration or necrosis; severe tissue damage; operative intervention indicated Grade 3 Injection Site Reaction, CTCAE Grade 3 Injection site reaction 10022095 C145382 Grade 3 Injection site reaction Grade 3 Injection site reaction Ulceration or necrosis; severe tissue damage; operative intervention indicated NCI Ulceration or necrosis; severe tissue damage; operative intervention indicated CTCAE_v5 Grade 3 Injection Site Reaction, CTCAE PT NCI Grade 3 Injection site reaction PT CTCAE_v5 ctcae5:C145383 Severe symptoms; limiting self care ADL (e.g., transient cerebral ischemia); repair or revision indicated Severe symptoms; limiting self care ADL (e.g., transient cerebral ischemia); repair or revision indicated Grade 3 Injury To Carotid Artery, CTCAE Grade 3 Injury to carotid artery 10022161 C145383 Grade 3 Injury to carotid artery Grade 3 Injury to carotid artery Severe symptoms; limiting self care ADL (e.g., transient cerebral ischemia); repair or revision indicated NCI Severe symptoms; limiting self care ADL (e.g., transient cerebral ischemia); repair or revision indicated CTCAE_v5 Grade 3 Injury To Carotid Artery, CTCAE PT NCI Grade 3 Injury to carotid artery PT CTCAE_v5 ctcae5:C145385 Symptomatic limiting self care ADL; repair or revision indicated Symptomatic limiting self care ADL; repair or revision indicated Grade 3 Injury To Jugular Vein, CTCAE Grade 3 Injury to jugular vein 10065849 C145385 Grade 3 Injury to jugular vein Grade 3 Injury to jugular vein Symptomatic limiting self care ADL; repair or revision indicated NCI Symptomatic limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Injury To Jugular Vein, CTCAE PT NCI Grade 3 Injury to jugular vein PT CTCAE_v5 ctcae5:C145386 Severe symptoms; limiting self care ADL; repair or revision indicated Severe symptoms; limiting self care ADL; repair or revision indicated Grade 3 Injury To Superior Vena Cava, CTCAE Grade 3 Injury to superior vena cava 10022356 C145386 Grade 3 Injury to superior vena cava Grade 3 Injury to superior vena cava Severe symptoms; limiting self care ADL; repair or revision indicated NCI Severe symptoms; limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Injury To Superior Vena Cava, CTCAE PT NCI Grade 3 Injury to superior vena cava PT CTCAE_v5 ctcae5:C145387 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Grade 3 Injury, poisoning and procedural complications - Other, specify 10022117 C145387 Grade 3 Injury, poisoning and procedural complications - Other, specify Grade 3 Injury, poisoning and procedural complications - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Grade 3 Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C145388 >2.5; >2.5 x baseline if on anticoagulation; bleeding >2.5; >2.5 x baseline if on anticoagulation; bleeding Grade 3 INR Increased, CTCAE Grade 3 INR increased 10022402 C145388 Grade 3 INR increased Grade 3 INR increased >2.5; >2.5 x baseline if on anticoagulation; bleeding NCI >2.5; >2.5 x baseline if on anticoagulation; bleeding CTCAE_v5 Grade 3 INR Increased, CTCAE PT NCI Grade 3 INR increased PT CTCAE_v5 ctcae5:C145389 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Intestinal Stoma Leak, CTCAE Grade 3 Intestinal stoma leak 10059095 C145389 Grade 3 Intestinal stoma leak Grade 3 Intestinal stoma leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Intestinal Stoma Leak, CTCAE PT NCI Grade 3 Intestinal stoma leak PT CTCAE_v5 ctcae5:C145390 Severe symptoms; IV fluids, tube feeding, or TPN indicated >=24 hrs; elective operative intervention indicated Severe symptoms; IV fluids, tube feeding, or TPN indicated >=24 hrs; elective operative intervention indicated Grade 3 Intestinal Stoma Obstruction, CTCAE Grade 3 Intestinal stoma obstruction 10059094 C145390 Grade 3 Intestinal stoma obstruction Grade 3 Intestinal stoma obstruction Severe symptoms; IV fluids, tube feeding, or TPN indicated >=24 hrs; elective operative intervention indicated NCI Severe symptoms; IV fluids, tube feeding, or TPN indicated >=24 hrs; elective operative intervention indicated CTCAE_v5 Grade 3 Intestinal Stoma Obstruction, CTCAE PT NCI Grade 3 Intestinal stoma obstruction PT CTCAE_v5 ctcae5:C145391 Transfusion indicated; invasive intervention indicated Transfusion indicated; invasive intervention indicated Grade 3 Intestinal Stoma Site Bleeding, CTCAE Grade 3 Intestinal stoma site bleeding 10049468 C145391 Grade 3 Intestinal stoma site bleeding Grade 3 Intestinal stoma site bleeding Transfusion indicated; invasive intervention indicated NCI Transfusion indicated; invasive intervention indicated CTCAE_v5 Grade 3 Intestinal Stoma Site Bleeding, CTCAE PT NCI Grade 3 Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C145392 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Intra-Abdominal Hemorrhage, CTCAE Grade 3 Intra-abdominal hemorrhage 10055291 C145392 Grade 3 Intra-abdominal hemorrhage Grade 3 Intra-abdominal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Intra-Abdominal Hemorrhage, CTCAE PT NCI Grade 3 Intra-abdominal hemorrhage PT CTCAE_v5 ctcae5:C145393 Ventriculostomy, ICP monitoring, intraventricular thrombolysis, or invasive intervention indicated; hospitalization Ventriculostomy, ICP monitoring, intraventricular thrombolysis, or invasive intervention indicated; hospitalization Grade 3 Intracranial Hemorrhage, CTCAE Grade 3 Intracranial hemorrhage 10022763 C145393 Grade 3 Intracranial hemorrhage Grade 3 Intracranial hemorrhage Ventriculostomy, ICP monitoring, intraventricular thrombolysis, or invasive intervention indicated; hospitalization NCI Ventriculostomy, ICP monitoring, intraventricular thrombolysis, or invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Intracranial Hemorrhage, CTCAE PT NCI Grade 3 Intracranial hemorrhage PT CTCAE_v5 ctcae5:C145394 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Arterial Injury, CTCAE Grade 3 Intraoperative arterial injury 10065826 C145394 Grade 3 Intraoperative arterial injury Grade 3 Intraoperative arterial injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Arterial Injury, CTCAE PT NCI Grade 3 Intraoperative arterial injury PT CTCAE_v5 ctcae5:C145395 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Breast Injury, CTCAE Grade 3 Intraoperative breast injury 10065831 C145395 Grade 3 Intraoperative breast injury Grade 3 Intraoperative breast injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Breast Injury, CTCAE PT NCI Grade 3 Intraoperative breast injury PT CTCAE_v5 ctcae5:C145396 Primary repair of injured organ/structure indicated Primary repair of injured organ/structure indicated Grade 3 Intraoperative Cardiac Injury, CTCAE Grade 3 Intraoperative cardiac injury 10065843 C145396 Grade 3 Intraoperative cardiac injury Grade 3 Intraoperative cardiac injury Primary repair of injured organ/structure indicated NCI Primary repair of injured organ/structure indicated CTCAE_v5 Grade 3 Intraoperative Cardiac Injury, CTCAE PT NCI Grade 3 Intraoperative cardiac injury PT CTCAE_v5 ctcae5:C145397 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL (e.g., impaired hearing; impaired balance) Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL (e.g., impaired hearing; impaired balance) Grade 3 Intraoperative Ear Injury, CTCAE Grade 3 Intraoperative ear injury 10065844 C145397 Grade 3 Intraoperative ear injury Grade 3 Intraoperative ear injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL (e.g., impaired hearing; impaired balance) NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL (e.g., impaired hearing; impaired balance) CTCAE_v5 Grade 3 Intraoperative Ear Injury, CTCAE PT NCI Grade 3 Intraoperative ear injury PT CTCAE_v5 ctcae5:C145398 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Endocrine Injury, CTCAE Grade 3 Intraoperative endocrine injury 10065834 C145398 Grade 3 Intraoperative endocrine injury Grade 3 Intraoperative endocrine injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Endocrine Injury, CTCAE PT NCI Grade 3 Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C145399 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Gastrointestinal Injury, CTCAE Grade 3 Intraoperative gastrointestinal injury 10065825 C145399 Grade 3 Intraoperative gastrointestinal injury Grade 3 Intraoperative gastrointestinal injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Grade 3 Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C145400 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Head and Neck Injury, CTCAE Grade 3 Intraoperative head and neck injury 10065842 C145400 Grade 3 Intraoperative head and neck injury Grade 3 Intraoperative head and neck injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Head and Neck Injury, CTCAE PT NCI Grade 3 Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C145401 Postoperative invasive intervention indicated; hospitalization Postoperative invasive intervention indicated; hospitalization Grade 3 Intraoperative Hemorrhage, CTCAE Grade 3 Intraoperative hemorrhage 10055298 C145401 Grade 3 Intraoperative hemorrhage Grade 3 Intraoperative hemorrhage Postoperative invasive intervention indicated; hospitalization NCI Postoperative invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Intraoperative Hemorrhage, CTCAE PT NCI Grade 3 Intraoperative hemorrhage PT CTCAE_v5 ctcae5:C145402 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Hepatobiliary Injury, CTCAE Grade 3 Intraoperative hepatobiliary injury 10065827 C145402 Grade 3 Intraoperative hepatobiliary injury Grade 3 Intraoperative hepatobiliary injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Grade 3 Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C145403 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Musculoskeletal Injury, CTCAE Grade 3 Intraoperative musculoskeletal injury 10065829 C145403 Grade 3 Intraoperative musculoskeletal injury Grade 3 Intraoperative musculoskeletal injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Grade 3 Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C145404 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Neurological Injury, CTCAE Grade 3 Intraoperative neurological injury 10065830 C145404 Grade 3 Intraoperative neurological injury Grade 3 Intraoperative neurological injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Neurological Injury, CTCAE PT NCI Grade 3 Intraoperative neurological injury PT CTCAE_v5 ctcae5:C145405 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Ocular Injury, CTCAE Grade 3 Intraoperative ocular injury 10065841 C145405 Grade 3 Intraoperative ocular injury Grade 3 Intraoperative ocular injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Ocular Injury, CTCAE PT NCI Grade 3 Intraoperative ocular injury PT CTCAE_v5 ctcae5:C145406 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Renal Injury, CTCAE Grade 3 Intraoperative renal injury 10065845 C145406 Grade 3 Intraoperative renal injury Grade 3 Intraoperative renal injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Renal Injury, CTCAE PT NCI Grade 3 Intraoperative renal injury PT CTCAE_v5 ctcae5:C145407 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Reproductive Tract Injury, CTCAE Grade 3 Intraoperative reproductive tract injury 10065840 C145407 Grade 3 Intraoperative reproductive tract injury Grade 3 Intraoperative reproductive tract injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Grade 3 Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C145408 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Respiratory Injury, CTCAE Grade 3 Intraoperative respiratory injury 10065832 C145408 Grade 3 Intraoperative respiratory injury Grade 3 Intraoperative respiratory injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Respiratory Injury, CTCAE PT NCI Grade 3 Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C145409 Resection or reconstruction of injured organ/structure indicated; limiting self care ADL Resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Splenic Injury, CTCAE Grade 3 Intraoperative splenic injury 10065847 C145409 Grade 3 Intraoperative splenic injury Grade 3 Intraoperative splenic injury Resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Splenic Injury, CTCAE PT NCI Grade 3 Intraoperative splenic injury PT CTCAE_v5 ctcae5:C145410 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Urinary Injury, CTCAE Grade 3 Intraoperative urinary injury 10065828 C145410 Grade 3 Intraoperative urinary injury Grade 3 Intraoperative urinary injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Urinary Injury, CTCAE PT NCI Grade 3 Intraoperative urinary injury PT CTCAE_v5 ctcae5:C145411 Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL Grade 3 Intraoperative Venous Injury, CTCAE Grade 3 Intraoperative venous injury 10065848 C145411 Grade 3 Intraoperative venous injury Grade 3 Intraoperative venous injury Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL NCI Complete resection or reconstruction of injured organ/structure indicated; limiting self care ADL CTCAE_v5 Grade 3 Intraoperative Venous Injury, CTCAE PT NCI Grade 3 Intraoperative venous injury PT CTCAE_v5 ctcae5:C145412 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Investigations - Other, Specify, CTCAE Grade 3 Investigations - Other, specify 10022891 C145412 Grade 3 Investigations - Other, specify Grade 3 Investigations - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Investigations - Other, Specify, CTCAE PT NCI Grade 3 Investigations - Other, specify PT CTCAE_v5 ctcae5:C145413 Severe abnormal or excessive response; limiting self care ADL; inconsolable; medical or psychiatric intervention indicated Severe abnormal or excessive response; limiting self care ADL; inconsolable; medical or psychiatric intervention indicated Grade 3 Irritability Grade 3 Irritability, CTCAE 10022998 C145413 Grade 3 Irritability Grade 3 Irritability Severe abnormal or excessive response; limiting self care ADL; inconsolable; medical or psychiatric intervention indicated NCI Severe abnormal or excessive response; limiting self care ADL; inconsolable; medical or psychiatric intervention indicated CTCAE_v5 Grade 3 Irritability PT CTCAE_v5 Grade 3 Irritability, CTCAE PT NCI ctcae5:C145417 Invasive intervention indicated Invasive intervention indicated Grade 3 Jejunal Perforation, CTCAE Grade 3 Jejunal perforation 10023174 C145417 Grade 3 Jejunal perforation Grade 3 Jejunal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Jejunal Perforation, CTCAE PT NCI Grade 3 Jejunal perforation PT CTCAE_v5 ctcae5:C145418 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Jejunal Stenosis, CTCAE Grade 3 Jejunal stenosis 10023176 C145418 Grade 3 Jejunal stenosis Grade 3 Jejunal stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Jejunal Stenosis, CTCAE PT NCI Grade 3 Jejunal stenosis PT CTCAE_v5 ctcae5:C145420 Arthroscopic intervention indicated (e.g., drainage) or arthrotomy (e.g., open surgical drainage) Arthroscopic intervention indicated (e.g., drainage) or arthrotomy (e.g., open surgical drainage) Grade 3 Joint Infection, CTCAE Grade 3 Joint infection 10023216 C145420 Grade 3 Joint infection Grade 3 Joint infection Arthroscopic intervention indicated (e.g., drainage) or arthrotomy (e.g., open surgical drainage) NCI Arthroscopic intervention indicated (e.g., drainage) or arthrotomy (e.g., open surgical drainage) CTCAE_v5 Grade 3 Joint Infection, CTCAE PT NCI Grade 3 Joint infection PT CTCAE_v5 ctcae5:C145421 Ankylosed/fused over multiple segments with no C-spine rotation Ankylosed/fused over multiple segments with no C-spine rotation Grade 3 Joint Range of Motion Decreased Cervical Spine, CTCAE Grade 3 Joint range of motion decreased cervical spine 10065796 C145421 Grade 3 Joint range of motion decreased cervical spine Grade 3 Joint range of motion decreased cervical spine Ankylosed/fused over multiple segments with no C-spine rotation NCI Ankylosed/fused over multiple segments with no C-spine rotation CTCAE_v5 Grade 3 Joint Range of Motion Decreased Cervical Spine, CTCAE PT NCI Grade 3 Joint range of motion decreased cervical spine PT CTCAE_v5 ctcae5:C145422 <50% lumbar spine flexion; associated with symptoms of ankylosis or fused over multiple segments with no L-spine flexion (e.g., unable to reach to floor to pick up a very light object) <50% lumbar spine flexion; associated with symptoms of ankylosis or fused over multiple segments with no L-spine flexion (e.g., unable to reach to floor to pick up a very light object) Grade 3 Joint Range of Motion Decreased Lumbar Spine, CTCAE Grade 3 Joint range of motion decreased lumbar spine 10065800 C145422 Grade 3 Joint range of motion decreased lumbar spine Grade 3 Joint range of motion decreased lumbar spine <50% lumbar spine flexion; associated with symptoms of ankylosis or fused over multiple segments with no L-spine flexion (e.g., unable to reach to floor to pick up a very light object) NCI <50% lumbar spine flexion; associated with symptoms of ankylosis or fused over multiple segments with no L-spine flexion (e.g., unable to reach to floor to pick up a very light object) CTCAE_v5 Grade 3 Joint Range of Motion Decreased Lumbar Spine, CTCAE PT NCI Grade 3 Joint range of motion decreased lumbar spine PT CTCAE_v5 ctcae5:C145423 >50% decrease in ROM; limiting self care ADL >50% decrease in ROM; limiting self care ADL Grade 3 Joint Range of Motion Decreased, CTCAE Grade 3 Joint range of motion decreased 10048706 C145423 Grade 3 Joint range of motion decreased Grade 3 Joint range of motion decreased >50% decrease in ROM; limiting self care ADL NCI >50% decrease in ROM; limiting self care ADL CTCAE_v5 Grade 3 Joint Range of Motion Decreased, CTCAE PT NCI Grade 3 Joint range of motion decreased PT CTCAE_v5 ctcae5:C145424 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Kidney Anastomotic Leak, CTCAE Grade 3 Kidney anastomotic leak 10065803 C145424 Grade 3 Kidney anastomotic leak Grade 3 Kidney anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Kidney Anastomotic Leak, CTCAE PT NCI Grade 3 Kidney anastomotic leak PT CTCAE_v5 ctcae5:C145425 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Kidney Infection, CTCAE Grade 3 Kidney infection 10023424 C145425 Grade 3 Kidney infection Grade 3 Kidney infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Kidney Infection, CTCAE PT NCI Grade 3 Kidney infection PT CTCAE_v5 ctcae5:C145426 Severe accentuation; operative intervention indicated; limiting self care ADL Severe accentuation; operative intervention indicated; limiting self care ADL Grade 3 Kyphosis Grade 3 Kyphosis, CTCAE 10023509 C145426 Grade 3 Kyphosis Grade 3 Kyphosis Severe accentuation; operative intervention indicated; limiting self care ADL NCI Severe accentuation; operative intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Kyphosis PT CTCAE_v5 Grade 3 Kyphosis, CTCAE PT NCI ctcae5:C145427 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Large Intestinal Anastomotic Leak, CTCAE Grade 3 Large intestinal anastomotic leak 10065891 C145427 Grade 3 Large intestinal anastomotic leak Grade 3 Large intestinal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Large Intestinal Anastomotic Leak, CTCAE PT NCI Grade 3 Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C145428 Stridor; respiratory distress; hospitalization indicated Stridor; respiratory distress; hospitalization indicated Grade 3 Laryngeal Edema, CTCAE Grade 3 Laryngeal edema 10023838 C145428 Grade 3 Laryngeal edema Grade 3 Laryngeal edema Stridor; respiratory distress; hospitalization indicated NCI Stridor; respiratory distress; hospitalization indicated CTCAE_v5 Grade 3 Laryngeal Edema, CTCAE PT NCI Grade 3 Laryngeal edema PT CTCAE_v5 ctcae5:C145431 Severe throat pain; endoscopic intervention indicated Severe throat pain; endoscopic intervention indicated Grade 3 Laryngeal Inflammation, CTCAE Grade 3 Laryngeal inflammation 10065735 C145431 Grade 3 Laryngeal inflammation Grade 3 Laryngeal inflammation Severe throat pain; endoscopic intervention indicated NCI Severe throat pain; endoscopic intervention indicated CTCAE_v5 Grade 3 Laryngeal Inflammation, CTCAE PT NCI Grade 3 Laryngeal inflammation PT CTCAE_v5 ctcae5:C145432 Severe pain; severely altered eating/swallowing; medical intervention indicated Severe pain; severely altered eating/swallowing; medical intervention indicated Grade 3 Laryngeal Mucositis, CTCAE Grade 3 Laryngeal mucositis 10065880 C145432 Grade 3 Laryngeal mucositis Grade 3 Laryngeal mucositis Severe pain; severely altered eating/swallowing; medical intervention indicated NCI Severe pain; severely altered eating/swallowing; medical intervention indicated CTCAE_v5 Grade 3 Laryngeal Mucositis, CTCAE PT NCI Grade 3 Laryngeal mucositis PT CTCAE_v5 ctcae5:C145433 Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Grade 3 Laryngeal Obstruction, CTCAE Grade 3 Laryngeal obstruction 10059639 C145433 Grade 3 Laryngeal obstruction Grade 3 Laryngeal obstruction Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) NCI Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Laryngeal Obstruction, CTCAE PT NCI Grade 3 Laryngeal obstruction PT CTCAE_v5 ctcae5:C145434 Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Grade 3 Laryngeal Stenosis, CTCAE Grade 3 Laryngeal stenosis 10023862 C145434 Grade 3 Laryngeal stenosis Grade 3 Laryngeal stenosis Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) NCI Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Laryngeal Stenosis, CTCAE PT NCI Grade 3 Laryngeal stenosis PT CTCAE_v5 ctcae5:C145435 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Laryngitis Grade 3 Laryngitis, CTCAE 10023874 C145435 Grade 3 Laryngitis Grade 3 Laryngitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Laryngitis PT CTCAE_v5 Grade 3 Laryngitis, CTCAE PT NCI ctcae5:C145436 Severe symptoms; dyspnea and swallowing difficulty; limiting self care ADL Severe symptoms; dyspnea and swallowing difficulty; limiting self care ADL Grade 3 Laryngopharyngeal Dysesthesia, CTCAE Grade 3 Laryngopharyngeal dysesthesia 10062667 C145436 Grade 3 Laryngopharyngeal dysesthesia Grade 3 Laryngopharyngeal dysesthesia Severe symptoms; dyspnea and swallowing difficulty; limiting self care ADL NCI Severe symptoms; dyspnea and swallowing difficulty; limiting self care ADL CTCAE_v5 Grade 3 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Grade 3 Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C145437 Recurrent episodes; noninvasive intervention indicated (e.g., breathing technique, pressure point massage) Recurrent episodes; noninvasive intervention indicated (e.g., breathing technique, pressure point massage) Grade 3 Laryngospasm Grade 3 Laryngospasm, CTCAE 10023891 C145437 Grade 3 Laryngospasm Grade 3 Laryngospasm Recurrent episodes; noninvasive intervention indicated (e.g., breathing technique, pressure point massage) NCI Recurrent episodes; noninvasive intervention indicated (e.g., breathing technique, pressure point massage) CTCAE_v5 Grade 3 Laryngospasm PT CTCAE_v5 Grade 3 Laryngospasm, CTCAE PT NCI ctcae5:C145438 >100,000/mm3 >100,000/mm3 Grade 3 Leukocytosis Grade 3 Leukocytosis, CTCAE 10024378 C145438 Grade 3 Leukocytosis Grade 3 Leukocytosis >100,000/mm3 NCI >100,000/mm3 CTCAE_v5 Grade 3 Leukocytosis PT CTCAE_v5 Grade 3 Leukocytosis, CTCAE PT NCI ctcae5:C145439 Severe symptoms; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving 2/3 or more of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly Severe symptoms; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving 2/3 or more of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly Grade 3 Leukoencephalopathy Grade 3 Leukoencephalopathy, CTCAE 10024382 C145439 Grade 3 Leukoencephalopathy Grade 3 Leukoencephalopathy Severe symptoms; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving 2/3 or more of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly NCI Severe symptoms; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving 2/3 or more of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly CTCAE_v5 Grade 3 Leukoencephalopathy PT CTCAE_v5 Grade 3 Leukoencephalopathy, CTCAE PT NCI ctcae5:C145440 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Lip Infection, CTCAE Grade 3 Lip infection 10065755 C145440 Grade 3 Lip infection Grade 3 Lip infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Lip Infection, CTCAE PT NCI Grade 3 Lip infection PT CTCAE_v5 ctcae5:C145441 >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic Grade 3 Lipase Increased, CTCAE Grade 3 Lipase increased 10024574 C145441 Grade 3 Lipase increased Grade 3 Lipase increased >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic NCI >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic CTCAE_v5 Grade 3 Lipase Increased, CTCAE PT NCI Grade 3 Lipase increased PT CTCAE_v5 ctcae5:C145442 Covering >30% BSA and associated tenderness and narcotics or NSAIDs indicated; lipohypertrophy; limiting self care ADL Covering >30% BSA and associated tenderness and narcotics or NSAIDs indicated; lipohypertrophy; limiting self care ADL Grade 3 Lipohypertrophy Grade 3 Lipohypertrophy, CTCAE 10062315 C145442 Grade 3 Lipohypertrophy Grade 3 Lipohypertrophy Covering >30% BSA and associated tenderness and narcotics or NSAIDs indicated; lipohypertrophy; limiting self care ADL NCI Covering >30% BSA and associated tenderness and narcotics or NSAIDs indicated; lipohypertrophy; limiting self care ADL CTCAE_v5 Grade 3 Lipohypertrophy PT CTCAE_v5 Grade 3 Lipohypertrophy, CTCAE PT NCI ctcae5:C145443 Severe localized edema and intervention indicated; limiting self care ADL Severe localized edema and intervention indicated; limiting self care ADL Grade 3 Localized Edema, CTCAE Grade 3 Localized edema 10062466 C145443 Grade 3 Localized edema Grade 3 Localized edema Severe localized edema and intervention indicated; limiting self care ADL NCI Severe localized edema and intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Localized Edema, CTCAE PT NCI Grade 3 Localized edema PT CTCAE_v5 ctcae5:C145444 Severe accentuation; operative intervention indicated; limiting self care ADL Severe accentuation; operative intervention indicated; limiting self care ADL Grade 3 Lordosis Grade 3 Lordosis, CTCAE 10024842 C145444 Grade 3 Lordosis Grade 3 Lordosis Severe accentuation; operative intervention indicated; limiting self care ADL NCI Severe accentuation; operative intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Lordosis PT CTCAE_v5 Grade 3 Lordosis, CTCAE PT NCI ctcae5:C145445 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Lower Gastrointestinal Hemorrhage, CTCAE Grade 3 Lower gastrointestinal hemorrhage 10051746 C145445 Grade 3 Lower gastrointestinal hemorrhage Grade 3 Lower gastrointestinal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 3 Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C145446 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Lung Infection, CTCAE Grade 3 Lung infection 10061229 C145446 Grade 3 Lung infection Grade 3 Lung infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Lung Infection, CTCAE PT NCI Grade 3 Lung infection PT CTCAE_v5 ctcae5:C145447 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Lymph Gland Infection, CTCAE Grade 3 Lymph gland infection 10050823 C145447 Grade 3 Lymph gland infection Grade 3 Lymph gland infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Lymph Gland Infection, CTCAE PT NCI Grade 3 Lymph gland infection PT CTCAE_v5 ctcae5:C145448 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Lymph Leakage, CTCAE Grade 3 Lymph leakage 10065773 C145448 Grade 3 Lymph leakage Grade 3 Lymph leakage Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Lymph Leakage, CTCAE PT NCI Grade 3 Lymph leakage PT CTCAE_v5 ctcae5:C145449 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Lymphedema Grade 3 Lymphedema, CTCAE 10025233 C145449 Grade 3 Lymphedema Grade 3 Lymphedema Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Lymphedema PT CTCAE_v5 Grade 3 Lymphedema, CTCAE PT NCI ctcae5:C145450 <500-200/mm3; <0.5-0.2 x 10e9/L <500-200/mm3; <0.5-0.2 x 10e9/L Grade 3 Lymphocyte Count Decreased, CTCAE Grade 3 Lymphocyte count decreased 10025256 C145450 Grade 3 Lymphocyte count decreased Grade 3 Lymphocyte count decreased <500-200/mm3; <0.5-0.2 x 10e9/L NCI <500-200/mm3; <0.5-0.2 x 10e9/L CTCAE_v5 Grade 3 Lymphocyte Count Decreased, CTCAE PT NCI Grade 3 Lymphocyte count decreased PT CTCAE_v5 ctcae5:C145451 >20,000/mm3 >20,000/mm3 Grade 3 Lymphocyte Count Increased, CTCAE Grade 3 Lymphocyte count increased 10025258 C145451 Grade 3 Lymphocyte count increased Grade 3 Lymphocyte count increased >20,000/mm3 NCI >20,000/mm3 CTCAE_v5 Grade 3 Lymphocyte Count Increased, CTCAE PT NCI Grade 3 Lymphocyte count increased PT CTCAE_v5 ctcae5:C145452 Uneasiness or lack of well being limiting self-care ADL Uneasiness or lack of well being limiting self-care ADL Grade 3 Malaise Grade 3 Malaise, CTCAE 10025482 C145452 Grade 3 Malaise Grade 3 Malaise Uneasiness or lack of well being limiting self-care ADL NCI Uneasiness or lack of well being limiting self-care ADL CTCAE_v5 Grade 3 Malaise PT CTCAE_v5 Grade 3 Malaise, CTCAE PT NCI ctcae5:C145453 Severe manic symptoms (e.g., hypomania; major sexual or financial indiscretions); hospitalization not indicated; new onset Severe manic symptoms (e.g., hypomania; major sexual or financial indiscretions); hospitalization not indicated; new onset Grade 3 Mania Grade 3 Mania, CTCAE 10026749 C145453 Grade 3 Mania Grade 3 Mania Severe manic symptoms (e.g., hypomania; major sexual or financial indiscretions); hospitalization not indicated; new onset NCI Severe manic symptoms (e.g., hypomania; major sexual or financial indiscretions); hospitalization not indicated; new onset CTCAE_v5 Grade 3 Mania PT CTCAE_v5 Grade 3 Mania, CTCAE PT NCI ctcae5:C145455 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Mediastinal Infection, CTCAE Grade 3 Mediastinal infection 10057483 C145455 Grade 3 Mediastinal infection Grade 3 Mediastinal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Mediastinal Infection, CTCAE PT NCI Grade 3 Mediastinal infection PT CTCAE_v5 ctcae5:C145456 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Meningismus Grade 3 Meningismus, CTCAE 10027198 C145456 Grade 3 Meningismus Grade 3 Meningismus Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Meningismus PT CTCAE_v5 Grade 3 Meningismus, CTCAE PT NCI ctcae5:C145457 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; focal neurologic deficit IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; focal neurologic deficit Grade 3 Meningitis Grade 3 Meningitis, CTCAE 10027199 C145457 Grade 3 Meningitis Grade 3 Meningitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; focal neurologic deficit NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated; focal neurologic deficit CTCAE_v5 Grade 3 Meningitis PT CTCAE_v5 Grade 3 Meningitis, CTCAE PT NCI ctcae5:C145458 Severe; transfusion indicated; operative intervention indicated (e.g., hysterectomy) Severe; transfusion indicated; operative intervention indicated (e.g., hysterectomy) Grade 3 Menorrhagia Grade 3 Menorrhagia, CTCAE 10027313 C145458 Grade 3 Menorrhagia Grade 3 Menorrhagia Severe; transfusion indicated; operative intervention indicated (e.g., hysterectomy) NCI Severe; transfusion indicated; operative intervention indicated (e.g., hysterectomy) CTCAE_v5 Grade 3 Menorrhagia PT CTCAE_v5 Grade 3 Menorrhagia, CTCAE PT NCI ctcae5:C145459 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Grade 3 Metabolism and nutrition disorders - Other, specify 10027433 C145459 Grade 3 Metabolism and nutrition disorders - Other, specify Grade 3 Metabolism and nutrition disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Grade 3 Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C145460 Requiring urgent intervention Requiring urgent intervention Grade 3 Methemoglobinemia Grade 3 Methemoglobinemia, CTCAE 10027506 C145460 Grade 3 Methemoglobinemia Grade 3 Methemoglobinemia Requiring urgent intervention NCI Requiring urgent intervention CTCAE_v5 Grade 3 Methemoglobinemia PT CTCAE_v5 Grade 3 Methemoglobinemia, CTCAE PT NCI ctcae5:C145461 Mastoiditis; necrosis of canal soft tissue or bone Mastoiditis; necrosis of canal soft tissue or bone Grade 3 Middle Ear Inflammation, CTCAE Grade 3 Middle ear inflammation 10065838 C145461 Grade 3 Middle ear inflammation Grade 3 Middle ear inflammation Mastoiditis; necrosis of canal soft tissue or bone NCI Mastoiditis; necrosis of canal soft tissue or bone CTCAE_v5 Grade 3 Middle Ear Inflammation, CTCAE PT NCI Grade 3 Middle ear inflammation PT CTCAE_v5 ctcae5:C145462 Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Grade 3 Mitral Valve Disease, CTCAE Grade 3 Mitral valve disease 10061532 C145462 Grade 3 Mitral valve disease Grade 3 Mitral valve disease Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention NCI Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention CTCAE_v5 Grade 3 Mitral Valve Disease, CTCAE PT NCI Grade 3 Mitral valve disease PT CTCAE_v5 ctcae5:C145465 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Movements Involuntary, CTCAE Grade 3 Movements involuntary 10028041 C145465 Grade 3 Movements involuntary Grade 3 Movements involuntary Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Movements Involuntary, CTCAE PT NCI Grade 3 Movements involuntary PT CTCAE_v5 ctcae5:C145466 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Mucosal Infection, CTCAE Grade 3 Mucosal infection 10065764 C145466 Grade 3 Mucosal infection Grade 3 Mucosal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Mucosal Infection, CTCAE PT NCI Grade 3 Mucosal infection PT CTCAE_v5 ctcae5:C145467 Severe pain; interfering with oral intake Severe pain; interfering with oral intake Grade 3 Mucositis Oral, CTCAE Grade 3 Mucositis oral 10028130 C145467 Grade 3 Mucositis oral Grade 3 Mucositis oral Severe pain; interfering with oral intake NCI Severe pain; interfering with oral intake CTCAE_v5 Grade 3 Mucositis Oral, CTCAE PT NCI Grade 3 Mucositis oral PT CTCAE_v5 ctcae5:C145468 Shock with azotemia and acid-base disturbances; significant coagulation abnormalities Shock with azotemia and acid-base disturbances; significant coagulation abnormalities Grade 3 Multi-Organ Failure, CTCAE Grade 3 Multi-organ failure 10028154 C145468 Grade 3 Multi-organ failure Grade 3 Multi-organ failure Shock with azotemia and acid-base disturbances; significant coagulation abnormalities NCI Shock with azotemia and acid-base disturbances; significant coagulation abnormalities CTCAE_v5 Grade 3 Multi-Organ Failure, CTCAE PT NCI Grade 3 Multi-organ failure PT CTCAE_v5 ctcae5:C145469 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Muscle Cramp, CTCAE Grade 3 Muscle cramp 10028294 C145469 Grade 3 Muscle cramp Grade 3 Muscle cramp Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Muscle Cramp, CTCAE PT NCI Grade 3 Muscle cramp PT CTCAE_v5 ctcae5:C145470 Limiting self care ADL Limiting self care ADL Grade 3 Muscle Weakness Left-Sided, CTCAE Grade 3 Muscle weakness left-sided 10065780 C145470 Grade 3 Muscle weakness left-sided Grade 3 Muscle weakness left-sided Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Muscle Weakness Left-Sided, CTCAE PT NCI Grade 3 Muscle weakness left-sided PT CTCAE_v5 ctcae5:C145471 Limiting self care ADL Limiting self care ADL Grade 3 Muscle Weakness Lower Limb, CTCAE Grade 3 Muscle weakness lower limb 10065776 C145471 Grade 3 Muscle weakness lower limb Grade 3 Muscle weakness lower limb Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Muscle Weakness Lower Limb, CTCAE PT NCI Grade 3 Muscle weakness lower limb PT CTCAE_v5 ctcae5:C145472 Limiting self care ADL Limiting self care ADL Grade 3 Muscle Weakness Right-Sided, CTCAE Grade 3 Muscle weakness right-sided 10065794 C145472 Grade 3 Muscle weakness right-sided Grade 3 Muscle weakness right-sided Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Muscle Weakness Right-Sided, CTCAE PT NCI Grade 3 Muscle weakness right-sided PT CTCAE_v5 ctcae5:C145473 Limiting self care ADL Limiting self care ADL Grade 3 Muscle Weakness Trunk, CTCAE Grade 3 Muscle weakness trunk 10065795 C145473 Grade 3 Muscle weakness trunk Grade 3 Muscle weakness trunk Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Muscle Weakness Trunk, CTCAE PT NCI Grade 3 Muscle weakness trunk PT CTCAE_v5 ctcae5:C145474 Limiting self care ADL Limiting self care ADL Grade 3 Muscle Weakness Upper Limb, CTCAE Grade 3 Muscle weakness upper limb 10065895 C145474 Grade 3 Muscle weakness upper limb Grade 3 Muscle weakness upper limb Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Muscle Weakness Upper Limb, CTCAE PT NCI Grade 3 Muscle weakness upper limb PT CTCAE_v5 ctcae5:C145475 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Grade 3 Musculoskeletal and connective tissue disorder - Other, specify 10028395 C145475 Grade 3 Musculoskeletal and connective tissue disorder - Other, specify Grade 3 Musculoskeletal and connective tissue disorder - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Grade 3 Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C145476 Significant deformity, hypoplasia, or asymmetry, unable to be remediated by prosthesis or covered by clothing; limiting self care ADL Significant deformity, hypoplasia, or asymmetry, unable to be remediated by prosthesis or covered by clothing; limiting self care ADL Grade 3 Musculoskeletal Deformity, CTCAE Grade 3 Musculoskeletal deformity 10065783 C145476 Grade 3 Musculoskeletal deformity Grade 3 Musculoskeletal deformity Significant deformity, hypoplasia, or asymmetry, unable to be remediated by prosthesis or covered by clothing; limiting self care ADL NCI Significant deformity, hypoplasia, or asymmetry, unable to be remediated by prosthesis or covered by clothing; limiting self care ADL CTCAE_v5 Grade 3 Musculoskeletal Deformity, CTCAE PT NCI Grade 3 Musculoskeletal deformity PT CTCAE_v5 ctcae5:C145477 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Myalgia Grade 3 Myalgia, CTCAE 10028411 C145477 Grade 3 Myalgia Grade 3 Myalgia Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Myalgia PT CTCAE_v5 Grade 3 Myalgia, CTCAE PT NCI ctcae5:C145478 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Myasthenia Gravis, CTCAE Grade 3 Myasthenia gravis 10028417 C145478 Grade 3 Myasthenia gravis Grade 3 Myasthenia gravis Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Myasthenia Gravis, CTCAE PT NCI Grade 3 Myasthenia gravis PT CTCAE_v5 ctcae5:C145479 Severe symptoms; cardiac enzymes abnormal; hemodynamically stable; ECG changes consistent with infarction Severe symptoms; cardiac enzymes abnormal; hemodynamically stable; ECG changes consistent with infarction Grade 3 Myocardial Infarction, CTCAE Grade 3 Myocardial infarction 10028596 C145479 Grade 3 Myocardial infarction Grade 3 Myocardial infarction Severe symptoms; cardiac enzymes abnormal; hemodynamically stable; ECG changes consistent with infarction NCI Severe symptoms; cardiac enzymes abnormal; hemodynamically stable; ECG changes consistent with infarction CTCAE_v5 Grade 3 Myocardial Infarction, CTCAE PT NCI Grade 3 Myocardial infarction PT CTCAE_v5 ctcae5:C145480 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Nail Infection, CTCAE Grade 3 Nail infection 10061304 C145480 Grade 3 Nail infection Grade 3 Nail infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Nail Infection, CTCAE PT NCI Grade 3 Nail infection PT CTCAE_v5 ctcae5:C145481 Associated with bloody nasal discharge or epistaxis Associated with bloody nasal discharge or epistaxis Grade 3 Nasal Congestion, CTCAE Grade 3 Nasal congestion 10028735 C145481 Grade 3 Nasal congestion Grade 3 Nasal congestion Associated with bloody nasal discharge or epistaxis NCI Associated with bloody nasal discharge or epistaxis CTCAE_v5 Grade 3 Nasal Congestion, CTCAE PT NCI Grade 3 Nasal congestion PT CTCAE_v5 ctcae5:C145482 Generalized neck edema (e.g., difficulty in turning neck); limiting self care ADL Generalized neck edema (e.g., difficulty in turning neck); limiting self care ADL Grade 3 Neck Edema, CTCAE Grade 3 Neck edema 10054482 C145482 Grade 3 Neck edema Grade 3 Neck edema Generalized neck edema (e.g., difficulty in turning neck); limiting self care ADL NCI Generalized neck edema (e.g., difficulty in turning neck); limiting self care ADL CTCAE_v5 Grade 3 Neck Edema, CTCAE PT NCI Grade 3 Neck edema PT CTCAE_v5 ctcae5:C145483 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Grade 3 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C145483 Grade 3 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Grade 3 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Grade 3 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C145484 Not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Nephrotic Syndrome, CTCAE Grade 3 Nephrotic syndrome 10029164 C145484 Grade 3 Nephrotic syndrome Grade 3 Nephrotic syndrome Not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Nephrotic Syndrome, CTCAE PT NCI Grade 3 Nephrotic syndrome PT CTCAE_v5 ctcae5:C145485 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Nervous System Disorders - Other, Specify, CTCAE Grade 3 Nervous system disorders - Other, specify 10029205 C145485 Grade 3 Nervous system disorders - Other, specify Grade 3 Nervous system disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Nervous System Disorders - Other, Specify, CTCAE PT NCI Grade 3 Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C145486 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Neuralgia Grade 3 Neuralgia, CTCAE 10029223 C145486 Grade 3 Neuralgia Grade 3 Neuralgia Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Neuralgia PT CTCAE_v5 Grade 3 Neuralgia, CTCAE PT NCI ctcae5:C145487 <1000-500/mm3; <1.0-0.5 x 10e9/L <1000-500/mm3; <1.0-0.5 x 10e9/L Grade 3 Neutrophil Count Decreased, CTCAE Grade 3 Neutrophil count decreased 10029366 C145487 Grade 3 Neutrophil count decreased Grade 3 Neutrophil count decreased <1000-500/mm3; <1.0-0.5 x 10e9/L NCI <1000-500/mm3; <1.0-0.5 x 10e9/L CTCAE_v5 Grade 3 Neutrophil Count Decreased, CTCAE PT NCI Grade 3 Neutrophil count decreased PT CTCAE_v5 ctcae5:C145488 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Night Blindness, CTCAE Grade 3 Night blindness 10029404 C145488 Grade 3 Night blindness Grade 3 Night blindness Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Night Blindness, CTCAE PT NCI Grade 3 Night blindness PT CTCAE_v5 ctcae5:C145489 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Non-Cardiac Chest Pain, CTCAE Grade 3 Non-cardiac chest pain 10062501 C145489 Grade 3 Non-cardiac chest pain Grade 3 Non-cardiac chest pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Non-Cardiac Chest Pain, CTCAE PT NCI Grade 3 Non-cardiac chest pain PT CTCAE_v5 ctcae5:C145490 Hospitalization indicated; invasive intervention indicated; limiting self care ADL Hospitalization indicated; invasive intervention indicated; limiting self care ADL Grade 3 Obstruction Gastric, CTCAE Grade 3 Obstruction gastric 10029957 C145490 Grade 3 Obstruction gastric Grade 3 Obstruction gastric Hospitalization indicated; invasive intervention indicated; limiting self care ADL NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Obstruction Gastric, CTCAE PT NCI Grade 3 Obstruction gastric PT CTCAE_v5 ctcae5:C145491 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Oculomotor Nerve Disorder, CTCAE Grade 3 Oculomotor nerve disorder 10053661 C145491 Grade 3 Oculomotor nerve disorder Grade 3 Oculomotor nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Oculomotor Nerve Disorder, CTCAE PT NCI Grade 3 Oculomotor nerve disorder PT CTCAE_v5 ctcae5:C145492 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Olfactory Nerve Disorder, CTCAE Grade 3 Olfactory nerve disorder 10056388 C145492 Grade 3 Olfactory nerve disorder Grade 3 Olfactory nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Olfactory Nerve Disorder, CTCAE PT NCI Grade 3 Olfactory nerve disorder PT CTCAE_v5 ctcae5:C145493 Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Grade 3 Optic Nerve Disorder, CTCAE Grade 3 Optic nerve disorder 10061322 C145493 Grade 3 Optic nerve disorder Grade 3 Optic nerve disorder Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) NCI Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) CTCAE_v5 Grade 3 Optic Nerve Disorder, CTCAE PT NCI Grade 3 Optic nerve disorder PT CTCAE_v5 ctcae5:C145494 Invasive intervention indicated Invasive intervention indicated Grade 3 Oral Cavity Fistula, CTCAE Grade 3 Oral cavity fistula 10065720 C145494 Grade 3 Oral cavity fistula Grade 3 Oral cavity fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Oral Cavity Fistula, CTCAE PT NCI Grade 3 Oral cavity fistula PT CTCAE_v5 ctcae5:C145495 Disabling pain; tube feeding or TPN indicated Disabling pain; tube feeding or TPN indicated Grade 3 Oral Dysesthesia, CTCAE Grade 3 Oral dysesthesia 10054520 C145495 Grade 3 Oral dysesthesia Grade 3 Oral dysesthesia Disabling pain; tube feeding or TPN indicated NCI Disabling pain; tube feeding or TPN indicated CTCAE_v5 Grade 3 Oral Dysesthesia, CTCAE PT NCI Grade 3 Oral dysesthesia PT CTCAE_v5 ctcae5:C145498 Severe pain; severely altered eating/swallowing; narcotics initiated; requires parenteral nutrition Severe pain; severely altered eating/swallowing; narcotics initiated; requires parenteral nutrition Grade 3 Oropharyngeal Pain, CTCAE Grade 3 Oropharyngeal pain 10068319 C145498 Grade 3 Oropharyngeal pain Grade 3 Oropharyngeal pain Severe pain; severely altered eating/swallowing; narcotics initiated; requires parenteral nutrition NCI Severe pain; severely altered eating/swallowing; narcotics initiated; requires parenteral nutrition CTCAE_v5 Grade 3 Oropharyngeal Pain, CTCAE PT NCI Grade 3 Oropharyngeal pain PT CTCAE_v5 ctcae5:C145499 Severe symptoms; limiting self care ADL; elective operative intervention indicated Severe symptoms; limiting self care ADL; elective operative intervention indicated Grade 3 Osteonecrosis of Jaw, CTCAE Grade 3 Osteonecrosis of jaw 10064658 C145499 Grade 3 Osteonecrosis of jaw Grade 3 Osteonecrosis of jaw Severe symptoms; limiting self care ADL; elective operative intervention indicated NCI Severe symptoms; limiting self care ADL; elective operative intervention indicated CTCAE_v5 Grade 3 Osteonecrosis of Jaw, CTCAE PT NCI Grade 3 Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C145500 Severe symptoms; limiting self care ADL; elective operative intervention indicated Severe symptoms; limiting self care ADL; elective operative intervention indicated Grade 3 Osteonecrosis Grade 3 Osteonecrosis, CTCAE 10031264 C145500 Grade 3 Osteonecrosis Grade 3 Osteonecrosis Severe symptoms; limiting self care ADL; elective operative intervention indicated NCI Severe symptoms; limiting self care ADL; elective operative intervention indicated CTCAE_v5 Grade 3 Osteonecrosis PT CTCAE_v5 Grade 3 Osteonecrosis, CTCAE PT NCI ctcae5:C145501 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Otitis Externa, CTCAE Grade 3 Otitis externa 10033072 C145501 Grade 3 Otitis externa Grade 3 Otitis externa IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Otitis Externa, CTCAE PT NCI Grade 3 Otitis externa PT CTCAE_v5 ctcae5:C145502 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Otitis Media, CTCAE Grade 3 Otitis media 10033078 C145502 Grade 3 Otitis media Grade 3 Otitis media IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Otitis Media, CTCAE PT NCI Grade 3 Otitis media PT CTCAE_v5 ctcae5:C145504 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Ovarian Infection, CTCAE Grade 3 Ovarian infection 10055005 C145504 Grade 3 Ovarian infection Grade 3 Ovarian infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Ovarian Infection, CTCAE PT NCI Grade 3 Ovarian infection PT CTCAE_v5 ctcae5:C145505 Transfusion; invasive intervention indicated Transfusion; invasive intervention indicated Grade 3 Ovarian Rupture, CTCAE Grade 3 Ovarian rupture 10033279 C145505 Grade 3 Ovarian rupture Grade 3 Ovarian rupture Transfusion; invasive intervention indicated NCI Transfusion; invasive intervention indicated CTCAE_v5 Grade 3 Ovarian Rupture, CTCAE PT NCI Grade 3 Ovarian rupture PT CTCAE_v5 ctcae5:C145506 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pain In Extremity, CTCAE Grade 3 Pain in extremity 10033425 C145506 Grade 3 Pain in extremity Grade 3 Pain in extremity Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pain In Extremity, CTCAE PT NCI Grade 3 Pain in extremity PT CTCAE_v5 ctcae5:C145507 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pain of Skin, CTCAE Grade 3 Pain of skin 10033474 C145507 Grade 3 Pain of skin Grade 3 Pain of skin Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pain of Skin, CTCAE PT NCI Grade 3 Pain of skin PT CTCAE_v5 ctcae5:C145508 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pain Grade 3 Pain, CTCAE 10033371 C145508 Grade 3 Pain Grade 3 Pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pain PT CTCAE_v5 Grade 3 Pain, CTCAE PT NCI ctcae5:C145509 Severe skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self care ADL Severe skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self care ADL Grade 3 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE Grade 3 Palmar-plantar erythrodysesthesia syndrome 10054524 C145509 Grade 3 Palmar-plantar erythrodysesthesia syndrome Grade 3 Palmar-plantar erythrodysesthesia syndrome Severe skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self care ADL NCI Severe skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self care ADL CTCAE_v5 Grade 3 Palmar-Plantar Erythrodysesthesia Syndrome, CTCAE PT NCI Grade 3 Palmar-plantar erythrodysesthesia syndrome PT CTCAE_v5 ctcae5:C145510 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Pancreas Infection, CTCAE Grade 3 Pancreas infection 10051741 C145510 Grade 3 Pancreas infection Grade 3 Pancreas infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Pancreas Infection, CTCAE PT NCI Grade 3 Pancreas infection PT CTCAE_v5 ctcae5:C145511 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Pancreatic Anastomotic Leak, CTCAE Grade 3 Pancreatic anastomotic leak 10050457 C145511 Grade 3 Pancreatic anastomotic leak Grade 3 Pancreatic anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Pancreatic Anastomotic Leak, CTCAE PT NCI Grade 3 Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C145512 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Pancreatic Duct Stenosis, CTCAE Grade 3 Pancreatic duct stenosis 10065703 C145512 Grade 3 Pancreatic duct stenosis Grade 3 Pancreatic duct stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Pancreatic Duct Stenosis, CTCAE PT NCI Grade 3 Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C145513 Sequelae of absorption deficiency Sequelae of absorption deficiency Grade 3 Pancreatic Enzymes Decreased, CTCAE Grade 3 Pancreatic enzymes decreased 10062646 C145513 Grade 3 Pancreatic enzymes decreased Grade 3 Pancreatic enzymes decreased Sequelae of absorption deficiency NCI Sequelae of absorption deficiency CTCAE_v5 Grade 3 Pancreatic Enzymes Decreased, CTCAE PT NCI Grade 3 Pancreatic enzymes decreased PT CTCAE_v5 ctcae5:C145516 Tube feeding or TPN indicated; invasive intervention indicated Tube feeding or TPN indicated; invasive intervention indicated Grade 3 Pancreatic Necrosis, CTCAE Grade 3 Pancreatic necrosis 10058096 C145516 Grade 3 Pancreatic necrosis Grade 3 Pancreatic necrosis Tube feeding or TPN indicated; invasive intervention indicated NCI Tube feeding or TPN indicated; invasive intervention indicated CTCAE_v5 Grade 3 Pancreatic Necrosis, CTCAE PT NCI Grade 3 Pancreatic necrosis PT CTCAE_v5 ctcae5:C145517 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Grade 3 Papilledema Grade 3 Papilledema, CTCAE 10033703 C145517 Grade 3 Papilledema Grade 3 Papilledema Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) CTCAE_v5 Grade 3 Papilledema PT CTCAE_v5 Grade 3 Papilledema, CTCAE PT NCI ctcae5:C145518 Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; IV antibiotics indicated Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; IV antibiotics indicated Grade 3 Papulopustular Rash, CTCAE Grade 3 Papulopustular rash 10069138 C145518 Grade 3 Papulopustular rash Grade 3 Papulopustular rash Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; IV antibiotics indicated NCI Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; IV antibiotics indicated CTCAE_v5 Grade 3 Papulopustular Rash, CTCAE PT NCI Grade 3 Papulopustular rash PT CTCAE_v5 ctcae5:C145519 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Paresthesia Grade 3 Paresthesia, CTCAE 10033987 C145519 Grade 3 Paresthesia Grade 3 Paresthesia Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Paresthesia PT CTCAE_v5 Grade 3 Paresthesia, CTCAE PT NCI ctcae5:C145520 Operative intervention indicated; IV antibiotics indicated; limiting self care ADL Operative intervention indicated; IV antibiotics indicated; limiting self care ADL Grade 3 Paronychia Grade 3 Paronychia, CTCAE 10034016 C145520 Grade 3 Paronychia Grade 3 Paronychia Operative intervention indicated; IV antibiotics indicated; limiting self care ADL NCI Operative intervention indicated; IV antibiotics indicated; limiting self care ADL CTCAE_v5 Grade 3 Paronychia PT CTCAE_v5 Grade 3 Paronychia, CTCAE PT NCI ctcae5:C145521 Symptomatic, urgent intervention indicated; ablation Symptomatic, urgent intervention indicated; ablation Grade 3 Paroxysmal Atrial Tachycardia, CTCAE Grade 3 Paroxysmal atrial tachycardia 10034040 C145521 Grade 3 Paroxysmal atrial tachycardia Grade 3 Paroxysmal atrial tachycardia Symptomatic, urgent intervention indicated; ablation NCI Symptomatic, urgent intervention indicated; ablation CTCAE_v5 Grade 3 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Grade 3 Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C145522 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Pelvic Floor Muscle Weakness, CTCAE Grade 3 Pelvic floor muscle weakness 10064026 C145522 Grade 3 Pelvic floor muscle weakness Grade 3 Pelvic floor muscle weakness Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Pelvic Floor Muscle Weakness, CTCAE PT NCI Grade 3 Pelvic floor muscle weakness PT CTCAE_v5 ctcae5:C145523 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Pelvic Infection, CTCAE Grade 3 Pelvic infection 10058674 C145523 Grade 3 Pelvic infection Grade 3 Pelvic infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Pelvic Infection, CTCAE PT NCI Grade 3 Pelvic infection PT CTCAE_v5 ctcae5:C145524 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pelvic Pain, CTCAE Grade 3 Pelvic pain 10034263 C145524 Grade 3 Pelvic pain Grade 3 Pelvic pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pelvic Pain, CTCAE PT NCI Grade 3 Pelvic pain PT CTCAE_v5 ctcae5:C145525 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Penile Infection, CTCAE Grade 3 Penile infection 10061912 C145525 Grade 3 Penile infection Grade 3 Penile infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Penile Infection, CTCAE PT NCI Grade 3 Penile infection PT CTCAE_v5 ctcae5:C145527 Invasive intervention indicated Invasive intervention indicated Grade 3 Perforation Bile Duct, CTCAE Grade 3 Perforation bile duct 10034405 C145527 Grade 3 Perforation bile duct Grade 3 Perforation bile duct Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Perforation Bile Duct, CTCAE PT NCI Grade 3 Perforation bile duct PT CTCAE_v5 ctcae5:C145528 Effusion with physiologic consequences Effusion with physiologic consequences Grade 3 Pericardial Effusion, CTCAE Grade 3 Pericardial effusion 10034474 C145528 Grade 3 Pericardial effusion Grade 3 Pericardial effusion Effusion with physiologic consequences NCI Effusion with physiologic consequences CTCAE_v5 Grade 3 Pericardial Effusion, CTCAE PT NCI Grade 3 Pericardial effusion PT CTCAE_v5 ctcae5:C145529 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Perineal Pain, CTCAE Grade 3 Perineal pain 10061339 C145529 Grade 3 Perineal pain Grade 3 Perineal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Perineal Pain, CTCAE PT NCI Grade 3 Perineal pain PT CTCAE_v5 ctcae5:C145530 Edema associated with visual disturbance; increased intraocular pressure, glaucoma or retinal hemorrhage; optic neuritis; diuretics indicated; operative intervention indicated Edema associated with visual disturbance; increased intraocular pressure, glaucoma or retinal hemorrhage; optic neuritis; diuretics indicated; operative intervention indicated Grade 3 Periorbital Edema, CTCAE Grade 3 Periorbital edema 10054541 C145530 Grade 3 Periorbital edema Grade 3 Periorbital edema Edema associated with visual disturbance; increased intraocular pressure, glaucoma or retinal hemorrhage; optic neuritis; diuretics indicated; operative intervention indicated NCI Edema associated with visual disturbance; increased intraocular pressure, glaucoma or retinal hemorrhage; optic neuritis; diuretics indicated; operative intervention indicated CTCAE_v5 Grade 3 Periorbital Edema, CTCAE PT NCI Grade 3 Periorbital edema PT CTCAE_v5 ctcae5:C145531 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Periorbital Infection, CTCAE Grade 3 Periorbital infection 10051472 C145531 Grade 3 Periorbital infection Grade 3 Periorbital infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Periorbital Infection, CTCAE PT NCI Grade 3 Periorbital infection PT CTCAE_v5 ctcae5:C145532 Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated Grade 3 Peripheral Ischemia, CTCAE Grade 3 Peripheral ischemia 10034578 C145532 Grade 3 Peripheral ischemia Grade 3 Peripheral ischemia Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated NCI Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated CTCAE_v5 Grade 3 Peripheral Ischemia, CTCAE PT NCI Grade 3 Peripheral ischemia PT CTCAE_v5 ctcae5:C145533 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Peripheral Motor Neuropathy, CTCAE Grade 3 Peripheral motor neuropathy 10034580 C145533 Grade 3 Peripheral motor neuropathy Grade 3 Peripheral motor neuropathy Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Peripheral Motor Neuropathy, CTCAE PT NCI Grade 3 Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C145534 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Peripheral Nerve Infection, CTCAE Grade 3 Peripheral nerve infection 10065766 C145534 Grade 3 Peripheral nerve infection Grade 3 Peripheral nerve infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Peripheral Nerve Infection, CTCAE PT NCI Grade 3 Peripheral nerve infection PT CTCAE_v5 ctcae5:C145535 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Peripheral Sensory Neuropathy, CTCAE Grade 3 Peripheral sensory neuropathy 10034620 C145535 Grade 3 Peripheral sensory neuropathy Grade 3 Peripheral sensory neuropathy Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Peripheral Sensory Neuropathy, CTCAE PT NCI Grade 3 Peripheral sensory neuropathy PT CTCAE_v5 ctcae5:C145536 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Peritoneal Infection, CTCAE Grade 3 Peritoneal infection 10057262 C145536 Grade 3 Peritoneal infection Grade 3 Peritoneal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Peritoneal Infection, CTCAE PT NCI Grade 3 Peritoneal infection PT CTCAE_v5 ctcae5:C145538 Severe personality change; hospitalization not indicated Severe personality change; hospitalization not indicated Grade 3 Personality Change, CTCAE Grade 3 Personality change 10034719 C145538 Grade 3 Personality change Grade 3 Personality change Severe personality change; hospitalization not indicated NCI Severe personality change; hospitalization not indicated CTCAE_v5 Grade 3 Personality Change, CTCAE PT NCI Grade 3 Personality change PT CTCAE_v5 ctcae5:C145539 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Phantom Pain, CTCAE Grade 3 Phantom pain 10056238 C145539 Grade 3 Phantom pain Grade 3 Phantom pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Phantom Pain, CTCAE PT NCI Grade 3 Phantom pain PT CTCAE_v5 ctcae5:C145540 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Pharyngeal Anastomotic Leak, CTCAE Grade 3 Pharyngeal anastomotic leak 10065705 C145540 Grade 3 Pharyngeal anastomotic leak Grade 3 Pharyngeal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Pharyngeal Anastomotic Leak, CTCAE PT NCI Grade 3 Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C145543 Severe pain; unable to adequately aliment or hydrate orally; limiting self care ADL Severe pain; unable to adequately aliment or hydrate orally; limiting self care ADL Grade 3 Pharyngeal Mucositis, CTCAE Grade 3 Pharyngeal mucositis 10065881 C145543 Grade 3 Pharyngeal mucositis Grade 3 Pharyngeal mucositis Severe pain; unable to adequately aliment or hydrate orally; limiting self care ADL NCI Severe pain; unable to adequately aliment or hydrate orally; limiting self care ADL CTCAE_v5 Grade 3 Pharyngeal Mucositis, CTCAE PT NCI Grade 3 Pharyngeal mucositis PT CTCAE_v5 ctcae5:C145545 Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) Grade 3 Pharyngeal Stenosis, CTCAE Grade 3 Pharyngeal stenosis 10050028 C145545 Grade 3 Pharyngeal stenosis Grade 3 Pharyngeal stenosis Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) NCI Limiting self care ADL; stridor; endoscopic intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Pharyngeal Stenosis, CTCAE PT NCI Grade 3 Pharyngeal stenosis PT CTCAE_v5 ctcae5:C145546 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Pharyngitis Grade 3 Pharyngitis, CTCAE 10034835 C145546 Grade 3 Pharyngitis Grade 3 Pharyngitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Pharyngitis PT CTCAE_v5 Grade 3 Pharyngitis, CTCAE PT NCI ctcae5:C145547 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pharyngolaryngeal Pain, CTCAE Grade 3 Pharyngolaryngeal pain 10034844 C145547 Grade 3 Pharyngolaryngeal pain Grade 3 Pharyngolaryngeal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pharyngolaryngeal Pain, CTCAE PT NCI Grade 3 Pharyngolaryngeal pain PT CTCAE_v5 ctcae5:C145548 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Phlebitis Infective, CTCAE Grade 3 Phlebitis infective 10056627 C145548 Grade 3 Phlebitis infective Grade 3 Phlebitis infective IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Phlebitis Infective, CTCAE PT NCI Grade 3 Phlebitis infective PT CTCAE_v5 ctcae5:C145549 <50,000-25,000/mm3; <50.0-25.0 x 10e9/L <50,000-25,000/mm3; <50.0-25.0 x 10e9/L Grade 3 Platelet Count Decreased, CTCAE Grade 3 Platelet count decreased 10035528 C145549 Grade 3 Platelet count decreased Grade 3 Platelet count decreased <50,000-25,000/mm3; <50.0-25.0 x 10e9/L NCI <50,000-25,000/mm3; <50.0-25.0 x 10e9/L CTCAE_v5 Grade 3 Platelet Count Decreased, CTCAE PT NCI Grade 3 Platelet count decreased PT CTCAE_v5 ctcae5:C145550 Symptomatic with respiratory distress and hypoxia; operative intervention including chest tube or pleurodesis indicated Symptomatic with respiratory distress and hypoxia; operative intervention including chest tube or pleurodesis indicated Grade 3 Pleural Effusion, CTCAE Grade 3 Pleural effusion 10035598 C145550 Grade 3 Pleural effusion Grade 3 Pleural effusion Symptomatic with respiratory distress and hypoxia; operative intervention including chest tube or pleurodesis indicated NCI Symptomatic with respiratory distress and hypoxia; operative intervention including chest tube or pleurodesis indicated CTCAE_v5 Grade 3 Pleural Effusion, CTCAE PT NCI Grade 3 Pleural effusion PT CTCAE_v5 ctcae5:C145552 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Pleural Infection, CTCAE Grade 3 Pleural infection 10061351 C145552 Grade 3 Pleural infection Grade 3 Pleural infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Pleural Infection, CTCAE PT NCI Grade 3 Pleural infection PT CTCAE_v5 ctcae5:C145553 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Pleuritic Pain, CTCAE Grade 3 Pleuritic pain 10035623 C145553 Grade 3 Pleuritic pain Grade 3 Pleuritic pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Pleuritic Pain, CTCAE PT NCI Grade 3 Pleuritic pain PT CTCAE_v5 ctcae5:C145554 Severe symptoms; limiting self care ADL; oxygen indicated Severe symptoms; limiting self care ADL; oxygen indicated Grade 3 Pneumonitis Grade 3 Pneumonitis, CTCAE 10035742 C145554 Grade 3 Pneumonitis Grade 3 Pneumonitis Severe symptoms; limiting self care ADL; oxygen indicated NCI Severe symptoms; limiting self care ADL; oxygen indicated CTCAE_v5 Grade 3 Pneumonitis PT CTCAE_v5 Grade 3 Pneumonitis, CTCAE PT NCI ctcae5:C145555 Reversal/retrograde portal vein flow; associated with varices and/or ascites Reversal/retrograde portal vein flow; associated with varices and/or ascites Grade 3 Portal Hypertension, CTCAE Grade 3 Portal hypertension 10036200 C145555 Grade 3 Portal hypertension Grade 3 Portal hypertension Reversal/retrograde portal vein flow; associated with varices and/or ascites NCI Reversal/retrograde portal vein flow; associated with varices and/or ascites CTCAE_v5 Grade 3 Portal Hypertension, CTCAE PT NCI Grade 3 Portal hypertension PT CTCAE_v5 ctcae5:C145556 Medical intervention indicated Medical intervention indicated Grade 3 Portal Vein Thrombosis, CTCAE Grade 3 Portal vein thrombosis 10036206 C145556 Grade 3 Portal vein thrombosis Grade 3 Portal vein thrombosis Medical intervention indicated NCI Medical intervention indicated CTCAE_v5 Grade 3 Portal Vein Thrombosis, CTCAE PT NCI Grade 3 Portal vein thrombosis PT CTCAE_v5 ctcae5:C145557 Transfusion indicated of >=2 units (10 cc/kg for pediatrics) pRBCs; invasive intervention indicated; hospitalization Transfusion indicated of >=2 units (10 cc/kg for pediatrics) pRBCs; invasive intervention indicated; hospitalization Grade 3 Postoperative Hemorrhage, CTCAE Grade 3 Postoperative hemorrhage 10055322 C145557 Grade 3 Postoperative hemorrhage Grade 3 Postoperative hemorrhage Transfusion indicated of >=2 units (10 cc/kg for pediatrics) pRBCs; invasive intervention indicated; hospitalization NCI Transfusion indicated of >=2 units (10 cc/kg for pediatrics) pRBCs; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Postoperative Hemorrhage, CTCAE PT NCI Grade 3 Postoperative hemorrhage PT CTCAE_v5 ctcae5:C145558 Extubated >72 hrs postoperatively, but before tracheostomy indicated Extubated >72 hrs postoperatively, but before tracheostomy indicated Grade 3 Postoperative Thoracic Procedure Complication, CTCAE Grade 3 Postoperative thoracic procedure complication 10056745 C145558 Grade 3 Postoperative thoracic procedure complication Grade 3 Postoperative thoracic procedure complication Extubated >72 hrs postoperatively, but before tracheostomy indicated NCI Extubated >72 hrs postoperatively, but before tracheostomy indicated CTCAE_v5 Grade 3 Postoperative Thoracic Procedure Complication, CTCAE PT NCI Grade 3 Postoperative thoracic procedure complication PT CTCAE_v5 ctcae5:C145559 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Grade 3 Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C145559 Grade 3 Pregnancy, puerperium and perinatal conditions - Other, specify Grade 3 Pregnancy, puerperium and perinatal conditions - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Grade 3 Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C145560 Delivery of a liveborn infant at 24 to 28 weeks gestation Delivery of a liveborn infant at 24 to 28 weeks gestation Grade 3 Premature Delivery, CTCAE Grade 3 Premature delivery 10036595 C145560 Grade 3 Premature delivery Grade 3 Premature delivery Delivery of a liveborn infant at 24 to 28 weeks gestation NCI Delivery of a liveborn infant at 24 to 28 weeks gestation CTCAE_v5 Grade 3 Premature Delivery, CTCAE PT NCI Grade 3 Premature delivery PT CTCAE_v5 ctcae5:C145561 Persistent or copious production of sputum; limiting self care ADL Persistent or copious production of sputum; limiting self care ADL Grade 3 Productive Cough, CTCAE Grade 3 Productive cough 10036790 C145561 Grade 3 Productive cough Grade 3 Productive cough Persistent or copious production of sputum; limiting self care ADL NCI Persistent or copious production of sputum; limiting self care ADL CTCAE_v5 Grade 3 Productive Cough, CTCAE PT NCI Grade 3 Productive cough PT CTCAE_v5 ctcae5:C145562 Severe symptoms; elective operative intervention indicated; limiting self care ADL Severe symptoms; elective operative intervention indicated; limiting self care ADL Grade 3 Prolapse of Intestinal Stoma, CTCAE Grade 3 Prolapse of intestinal stoma 10065745 C145562 Grade 3 Prolapse of intestinal stoma Grade 3 Prolapse of intestinal stoma Severe symptoms; elective operative intervention indicated; limiting self care ADL NCI Severe symptoms; elective operative intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Prolapse of Intestinal Stoma, CTCAE PT NCI Grade 3 Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C145563 Dysfunctional stoma; elective operative intervention or major stomal revision indicated Dysfunctional stoma; elective operative intervention or major stomal revision indicated Grade 3 Prolapse of Urostomy, CTCAE Grade 3 Prolapse of urostomy 10065822 C145563 Grade 3 Prolapse of urostomy Grade 3 Prolapse of urostomy Dysfunctional stoma; elective operative intervention or major stomal revision indicated NCI Dysfunctional stoma; elective operative intervention or major stomal revision indicated CTCAE_v5 Grade 3 Prolapse of Urostomy, CTCAE PT NCI Grade 3 Prolapse of urostomy PT CTCAE_v5 ctcae5:C145564 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Prostate Infection, CTCAE Grade 3 Prostate infection 10050662 C145564 Grade 3 Prostate infection Grade 3 Prostate infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Prostate Infection, CTCAE PT NCI Grade 3 Prostate infection PT CTCAE_v5 ctcae5:C145566 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Prostatic Obstruction, CTCAE Grade 3 Prostatic obstruction 10055026 C145566 Grade 3 Prostatic obstruction Grade 3 Prostatic obstruction Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Prostatic Obstruction, CTCAE PT NCI Grade 3 Prostatic obstruction PT CTCAE_v5 ctcae5:C145567 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Prostatic Pain, CTCAE Grade 3 Prostatic pain 10036968 C145567 Grade 3 Prostatic pain Grade 3 Prostatic pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Prostatic Pain, CTCAE PT NCI Grade 3 Prostatic pain PT CTCAE_v5 ctcae5:C145568 Severe or medically significant but not immediately life-threatening; limiting self care ADL Severe or medically significant but not immediately life-threatening; limiting self care ADL Grade 3 Psychiatric Disorders - Other, Specify, CTCAE Grade 3 Psychiatric disorders - Other, specify 10037175 C145568 Grade 3 Psychiatric disorders - Other, specify Grade 3 Psychiatric disorders - Other, specify Severe or medically significant but not immediately life-threatening; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; limiting self care ADL CTCAE_v5 Grade 3 Psychiatric Disorders - Other, Specify, CTCAE PT NCI Grade 3 Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C145569 Severe psychotic symptoms (e.g., paranoid, extreme disorganization); hospitalization not indicated; new onset Severe psychotic symptoms (e.g., paranoid, extreme disorganization); hospitalization not indicated; new onset Grade 3 Psychosis Grade 3 Psychosis, CTCAE 10037234 C145569 Grade 3 Psychosis Grade 3 Psychosis Severe psychotic symptoms (e.g., paranoid, extreme disorganization); hospitalization not indicated; new onset NCI Severe psychotic symptoms (e.g., paranoid, extreme disorganization); hospitalization not indicated; new onset CTCAE_v5 Grade 3 Psychosis PT CTCAE_v5 Grade 3 Psychosis, CTCAE PT NCI ctcae5:C145570 Severe dyspnea or dyspnea at rest; oxygen indicated; limiting self care ADL Severe dyspnea or dyspnea at rest; oxygen indicated; limiting self care ADL Grade 3 Pulmonary Edema, CTCAE Grade 3 Pulmonary edema 10037375 C145570 Grade 3 Pulmonary edema Grade 3 Pulmonary edema Severe dyspnea or dyspnea at rest; oxygen indicated; limiting self care ADL NCI Severe dyspnea or dyspnea at rest; oxygen indicated; limiting self care ADL CTCAE_v5 Grade 3 Pulmonary Edema, CTCAE PT NCI Grade 3 Pulmonary edema PT CTCAE_v5 ctcae5:C145571 Severe hypoxia; evidence of right-sided heart failure; radiographic pulmonary fibrosis >50-75% Severe hypoxia; evidence of right-sided heart failure; radiographic pulmonary fibrosis >50-75% Grade 3 Pulmonary Fibrosis, CTCAE Grade 3 Pulmonary fibrosis 10037383 C145571 Grade 3 Pulmonary fibrosis Grade 3 Pulmonary fibrosis Severe hypoxia; evidence of right-sided heart failure; radiographic pulmonary fibrosis >50-75% NCI Severe hypoxia; evidence of right-sided heart failure; radiographic pulmonary fibrosis >50-75% CTCAE_v5 Grade 3 Pulmonary Fibrosis, CTCAE PT NCI Grade 3 Pulmonary fibrosis PT CTCAE_v5 ctcae5:C145572 Invasive intervention indicated Invasive intervention indicated Grade 3 Pulmonary Fistula, CTCAE Grade 3 Pulmonary fistula 10065873 C145572 Grade 3 Pulmonary fistula Grade 3 Pulmonary fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Pulmonary Fistula, CTCAE PT NCI Grade 3 Pulmonary fistula PT CTCAE_v5 ctcae5:C145573 Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention Grade 3 Pulmonary Valve Disease, CTCAE Grade 3 Pulmonary valve disease 10061541 C145573 Grade 3 Pulmonary valve disease Grade 3 Pulmonary valve disease Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention NCI Symptomatic; severe regurgitation or stenosis by imaging; symptoms controlled with medical intervention CTCAE_v5 Grade 3 Pulmonary Valve Disease, CTCAE PT NCI Grade 3 Pulmonary valve disease PT CTCAE_v5 ctcae5:C145574 Combined area of lesions covering >30% BSA; spontaneous bleeding Combined area of lesions covering >30% BSA; spontaneous bleeding Grade 3 Purpura Grade 3 Purpura, CTCAE 10037549 C145574 Grade 3 Purpura Grade 3 Purpura Combined area of lesions covering >30% BSA; spontaneous bleeding NCI Combined area of lesions covering >30% BSA; spontaneous bleeding CTCAE_v5 Grade 3 Purpura PT CTCAE_v5 Grade 3 Purpura, CTCAE PT NCI ctcae5:C145575 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Pyramidal Tract Syndrome, CTCAE Grade 3 Pyramidal tract syndrome 10063636 C145575 Grade 3 Pyramidal tract syndrome Grade 3 Pyramidal tract syndrome Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Pyramidal Tract Syndrome, CTCAE PT NCI Grade 3 Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C145576 Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion Grade 3 Radiation Recall Reaction (Dermatologic), CTCAE Grade 3 Radiation recall reaction (dermatologic) 10037767 C145576 Grade 3 Radiation recall reaction (dermatologic) Grade 3 Radiation recall reaction (dermatologic) Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion NCI Moist desquamation in areas other than skin folds and creases; bleeding induced by minor trauma or abrasion CTCAE_v5 Grade 3 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Grade 3 Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C145577 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Radiculitis Grade 3 Radiculitis, CTCAE 10061928 C145577 Grade 3 Radiculitis Grade 3 Radiculitis Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Radiculitis PT CTCAE_v5 Grade 3 Radiculitis, CTCAE PT NCI ctcae5:C145578 Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; associated with local superinfection with oral antibiotics indicated Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; associated with local superinfection with oral antibiotics indicated Grade 3 Rash Acneiform, CTCAE Grade 3 Rash acneiform 10037847 C145578 Grade 3 Rash acneiform Grade 3 Rash acneiform Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; associated with local superinfection with oral antibiotics indicated NCI Papules and/or pustules covering >30% BSA with moderate or severe symptoms; limiting self-care ADL; associated with local superinfection with oral antibiotics indicated CTCAE_v5 Grade 3 Rash Acneiform, CTCAE PT NCI Grade 3 Rash acneiform PT CTCAE_v5 ctcae5:C145579 Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self care ADL Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self care ADL Grade 3 Rash Maculo-Papular, CTCAE Grade 3 Rash maculo-papular 10037868 C145579 Grade 3 Rash maculo-papular Grade 3 Rash maculo-papular Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self care ADL NCI Macules/papules covering >30% BSA with moderate or severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Rash Maculo-Papular, CTCAE PT NCI Grade 3 Rash maculo-papular PT CTCAE_v5 ctcae5:C145580 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Rash Pustular, CTCAE Grade 3 Rash pustular 10037888 C145580 Grade 3 Rash pustular Grade 3 Rash pustular IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Rash Pustular, CTCAE PT NCI Grade 3 Rash pustular PT CTCAE_v5 ctcae5:C145581 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Rectal Anastomotic Leak, CTCAE Grade 3 Rectal anastomotic leak 10065894 C145581 Grade 3 Rectal anastomotic leak Grade 3 Rectal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Rectal Anastomotic Leak, CTCAE PT NCI Grade 3 Rectal anastomotic leak PT CTCAE_v5 ctcae5:C145582 Invasive intervention indicated Invasive intervention indicated Grade 3 Rectal Fissure, CTCAE Grade 3 Rectal fissure 10064993 C145582 Grade 3 Rectal fissure Grade 3 Rectal fissure Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Rectal Fissure, CTCAE PT NCI Grade 3 Rectal fissure PT CTCAE_v5 ctcae5:C145585 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Rectal Mucositis, CTCAE Grade 3 Rectal mucositis 10063190 C145585 Grade 3 Rectal mucositis Grade 3 Rectal mucositis Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Rectal Mucositis, CTCAE PT NCI Grade 3 Rectal mucositis PT CTCAE_v5 ctcae5:C145588 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Rectal Pain, CTCAE Grade 3 Rectal pain 10038072 C145588 Grade 3 Rectal pain Grade 3 Rectal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Rectal Pain, CTCAE PT NCI Grade 3 Rectal pain PT CTCAE_v5 ctcae5:C145590 Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated Grade 3 Rectal Stenosis, CTCAE Grade 3 Rectal stenosis 10038079 C145590 Grade 3 Rectal stenosis Grade 3 Rectal stenosis Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Rectal Stenosis, CTCAE PT NCI Grade 3 Rectal stenosis PT CTCAE_v5 ctcae5:C145592 Severe symptoms; medical intervention indicated (e.g., thyroplasty, vocal cord injection) Severe symptoms; medical intervention indicated (e.g., thyroplasty, vocal cord injection) Grade 3 Recurrent Laryngeal Nerve Palsy, CTCAE Grade 3 Recurrent laryngeal nerve palsy 10038130 C145592 Grade 3 Recurrent laryngeal nerve palsy Grade 3 Recurrent laryngeal nerve palsy Severe symptoms; medical intervention indicated (e.g., thyroplasty, vocal cord injection) NCI Severe symptoms; medical intervention indicated (e.g., thyroplasty, vocal cord injection) CTCAE_v5 Grade 3 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Grade 3 Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C145593 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Renal and Urinary Disorders - Other, Specify, CTCAE Grade 3 Renal and urinary disorders - Other, specify 10038359 C145593 Grade 3 Renal and urinary disorders - Other, specify Grade 3 Renal and urinary disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Grade 3 Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C145594 Hospitalization indicated; IV intervention (e.g., analgesics, antiemetics); elective invasive intervention indicated Hospitalization indicated; IV intervention (e.g., analgesics, antiemetics); elective invasive intervention indicated Grade 3 Renal Calculi, CTCAE Grade 3 Renal calculi 10038385 C145594 Grade 3 Renal calculi Grade 3 Renal calculi Hospitalization indicated; IV intervention (e.g., analgesics, antiemetics); elective invasive intervention indicated NCI Hospitalization indicated; IV intervention (e.g., analgesics, antiemetics); elective invasive intervention indicated CTCAE_v5 Grade 3 Renal Calculi, CTCAE PT NCI Grade 3 Renal calculi PT CTCAE_v5 ctcae5:C145595 Hospitalization indicated; limiting self care ADL Hospitalization indicated; limiting self care ADL Grade 3 Renal Colic, CTCAE Grade 3 Renal colic 10038419 C145595 Grade 3 Renal colic Grade 3 Renal colic Hospitalization indicated; limiting self care ADL NCI Hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Renal Colic, CTCAE PT NCI Grade 3 Renal colic PT CTCAE_v5 ctcae5:C145597 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Reproductive System and Breast Disorders - Other, Specify, CTCAE Grade 3 Reproductive system and breast disorders - Other, specify 10038604 C145597 Grade 3 Reproductive system and breast disorders - Other, specify Grade 3 Reproductive system and breast disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Grade 3 Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C145598 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Grade 3 Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C145598 Grade 3 Respiratory, thoracic and mediastinal disorders - Other, specify Grade 3 Respiratory, thoracic and mediastinal disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Grade 3 Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C145599 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Restlessness Grade 3 Restlessness, CTCAE 10038743 C145599 Grade 3 Restlessness Grade 3 Restlessness Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Restlessness PT CTCAE_v5 Grade 3 Restlessness, CTCAE PT NCI ctcae5:C145600 Retinal vascular disorder with neovascularization Retinal vascular disorder with neovascularization Grade 3 Retinal Vascular Disorder, CTCAE Grade 3 Retinal vascular disorder 10038901 C145600 Grade 3 Retinal vascular disorder Grade 3 Retinal vascular disorder Retinal vascular disorder with neovascularization NCI Retinal vascular disorder with neovascularization CTCAE_v5 Grade 3 Retinal Vascular Disorder, CTCAE PT NCI Grade 3 Retinal vascular disorder PT CTCAE_v5 ctcae5:C145601 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Retroperitoneal Hemorrhage, CTCAE Grade 3 Retroperitoneal hemorrhage 10038981 C145601 Grade 3 Retroperitoneal hemorrhage Grade 3 Retroperitoneal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Retroperitoneal Hemorrhage, CTCAE PT NCI Grade 3 Retroperitoneal hemorrhage PT CTCAE_v5 ctcae5:C145602 Severe symptoms; limiting self care ADL; hospitalization Severe symptoms; limiting self care ADL; hospitalization Grade 3 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE Grade 3 Reversible posterior leukoencephalopathy syndrome 10063761 C145602 Grade 3 Reversible posterior leukoencephalopathy syndrome Grade 3 Reversible posterior leukoencephalopathy syndrome Severe symptoms; limiting self care ADL; hospitalization NCI Severe symptoms; limiting self care ADL; hospitalization CTCAE_v5 Grade 3 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE PT NCI Grade 3 Reversible posterior leukoencephalopathy syndrome PT CTCAE_v5 ctcae5:C145603 Symptomatic, urgent intervention indicated Symptomatic, urgent intervention indicated Grade 3 Rhabdomyolysis Grade 3 Rhabdomyolysis, CTCAE 10039020 C145603 Grade 3 Rhabdomyolysis Grade 3 Rhabdomyolysis Symptomatic, urgent intervention indicated NCI Symptomatic, urgent intervention indicated CTCAE_v5 Grade 3 Rhabdomyolysis PT CTCAE_v5 Grade 3 Rhabdomyolysis, CTCAE PT NCI ctcae5:C145604 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Rotator Cuff Injury, CTCAE Grade 3 Rotator cuff injury 10039226 C145604 Grade 3 Rotator cuff injury Grade 3 Rotator cuff injury Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Rotator Cuff Injury, CTCAE PT NCI Grade 3 Rotator cuff injury PT CTCAE_v5 ctcae5:C145605 Acute salivary gland necrosis; severe secretion-induced symptoms (e.g., thick saliva/oral secretions or gagging); tube feeding or TPN indicated; limiting self care ADL Acute salivary gland necrosis; severe secretion-induced symptoms (e.g., thick saliva/oral secretions or gagging); tube feeding or TPN indicated; limiting self care ADL Grade 3 Salivary Duct Inflammation, CTCAE Grade 3 Salivary duct inflammation 10056681 C145605 Grade 3 Salivary duct inflammation Grade 3 Salivary duct inflammation Acute salivary gland necrosis; severe secretion-induced symptoms (e.g., thick saliva/oral secretions or gagging); tube feeding or TPN indicated; limiting self care ADL NCI Acute salivary gland necrosis; severe secretion-induced symptoms (e.g., thick saliva/oral secretions or gagging); tube feeding or TPN indicated; limiting self care ADL CTCAE_v5 Grade 3 Salivary Duct Inflammation, CTCAE PT NCI Grade 3 Salivary duct inflammation PT CTCAE_v5 ctcae5:C145606 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Salivary Gland Infection, CTCAE Grade 3 Salivary gland infection 10039413 C145606 Grade 3 Salivary gland infection Grade 3 Salivary gland infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Salivary Gland Infection, CTCAE PT NCI Grade 3 Salivary gland infection PT CTCAE_v5 ctcae5:C145607 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Scleral Disorder, CTCAE Grade 3 Scleral disorder 10061510 C145607 Grade 3 Scleral disorder Grade 3 Scleral disorder Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Scleral Disorder, CTCAE PT NCI Grade 3 Scleral disorder PT CTCAE_v5 ctcae5:C145608 >45 degrees; scapular prominence in forward flexion; operative intervention indicated; limiting self care ADL >45 degrees; scapular prominence in forward flexion; operative intervention indicated; limiting self care ADL Grade 3 Scoliosis Grade 3 Scoliosis, CTCAE 10039722 C145608 Grade 3 Scoliosis Grade 3 Scoliosis >45 degrees; scapular prominence in forward flexion; operative intervention indicated; limiting self care ADL NCI >45 degrees; scapular prominence in forward flexion; operative intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Scoliosis PT CTCAE_v5 Grade 3 Scoliosis, CTCAE PT NCI ctcae5:C145609 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Scrotal Infection, CTCAE Grade 3 Scrotal infection 10062156 C145609 Grade 3 Scrotal infection Grade 3 Scrotal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Scrotal Infection, CTCAE PT NCI Grade 3 Scrotal infection PT CTCAE_v5 ctcae5:C145610 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Scrotal Pain, CTCAE Grade 3 Scrotal pain 10039757 C145610 Grade 3 Scrotal pain Grade 3 Scrotal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Scrotal Pain, CTCAE PT NCI Grade 3 Scrotal pain PT CTCAE_v5 ctcae5:C145611 Blood culture positive with signs or symptoms; treatment indicated Blood culture positive with signs or symptoms; treatment indicated Grade 3 Sepsis Grade 3 Sepsis, CTCAE 10040047 C145611 Grade 3 Sepsis Grade 3 Sepsis Blood culture positive with signs or symptoms; treatment indicated NCI Blood culture positive with signs or symptoms; treatment indicated CTCAE_v5 Grade 3 Sepsis PT CTCAE_v5 Grade 3 Sepsis, CTCAE PT NCI ctcae5:C145612 >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic Grade 3 Serum Amylase Increased, CTCAE Grade 3 Serum amylase increased 10040139 C145612 Grade 3 Serum amylase increased Grade 3 Serum amylase increased >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic NCI >2.0-5.0 x ULN with signs or symptoms; >5.0 x ULN and asymptomatic CTCAE_v5 Grade 3 Serum Amylase Increased, CTCAE PT NCI Grade 3 Serum amylase increased PT CTCAE_v5 ctcae5:C145613 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated; limiting self-care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated; limiting self-care ADL Grade 3 Shingles Grade 3 Shingles, CTCAE 10040555 C145613 Grade 3 Shingles Grade 3 Shingles Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated; limiting self-care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; IV intervention indicated; limiting self-care ADL CTCAE_v5 Grade 3 Shingles PT CTCAE_v5 Grade 3 Shingles, CTCAE PT NCI ctcae5:C145614 Stenosis with significant nasal obstruction; limiting self care ADL Stenosis with significant nasal obstruction; limiting self care ADL Grade 3 Sinus Disorder, CTCAE Grade 3 Sinus disorder 10062244 C145614 Grade 3 Sinus disorder Grade 3 Sinus disorder Stenosis with significant nasal obstruction; limiting self care ADL NCI Stenosis with significant nasal obstruction; limiting self care ADL CTCAE_v5 Grade 3 Sinus Disorder, CTCAE PT NCI Grade 3 Sinus disorder PT CTCAE_v5 ctcae5:C145615 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Sinusitis Grade 3 Sinusitis, CTCAE 10040753 C145615 Grade 3 Sinusitis Grade 3 Sinusitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Sinusitis PT CTCAE_v5 Grade 3 Sinusitis, CTCAE PT NCI ctcae5:C145616 Blood bilirubin >5 mg/dL; coagulation modifier indicated (e.g., defibrotide); reversal of flow on ultrasound Blood bilirubin >5 mg/dL; coagulation modifier indicated (e.g., defibrotide); reversal of flow on ultrasound Grade 3 Sinusoidal Obstruction Syndrome, CTCAE Grade 3 Sinusoidal obstruction syndrome 10063675 C145616 Grade 3 Sinusoidal obstruction syndrome Grade 3 Sinusoidal obstruction syndrome Blood bilirubin >5 mg/dL; coagulation modifier indicated (e.g., defibrotide); reversal of flow on ultrasound NCI Blood bilirubin >5 mg/dL; coagulation modifier indicated (e.g., defibrotide); reversal of flow on ultrasound CTCAE_v5 Grade 3 Sinusoidal Obstruction Syndrome, CTCAE PT NCI Grade 3 Sinusoidal obstruction syndrome PT CTCAE_v5 ctcae5:C145617 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Grade 3 Skin and subcutaneous tissue disorders - Other, specify 10040785 C145617 Grade 3 Skin and subcutaneous tissue disorders - Other, specify Grade 3 Skin and subcutaneous tissue disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Grade 3 Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C145618 Covering >30% BSA; associated with ulceration Covering >30% BSA; associated with ulceration Grade 3 Skin Atrophy, CTCAE Grade 3 Skin atrophy 10040799 C145618 Grade 3 Skin atrophy Grade 3 Skin atrophy Covering >30% BSA; associated with ulceration NCI Covering >30% BSA; associated with ulceration CTCAE_v5 Grade 3 Skin Atrophy, CTCAE PT NCI Grade 3 Skin atrophy PT CTCAE_v5 ctcae5:C145619 Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Grade 3 Skin Induration, CTCAE Grade 3 Skin induration 10051837 C145619 Grade 3 Skin induration Grade 3 Skin induration Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL NCI Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL CTCAE_v5 Grade 3 Skin Induration, CTCAE PT NCI Grade 3 Skin induration PT CTCAE_v5 ctcae5:C145620 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Skin Infection, CTCAE Grade 3 Skin infection 10040872 C145620 Grade 3 Skin infection Grade 3 Skin infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Skin Infection, CTCAE PT NCI Grade 3 Skin infection PT CTCAE_v5 ctcae5:C145621 Combined area of ulcers >2 cm; full-thickness skin loss involving damage to or necrosis of subcutaneous tissue that may extend down to fascia Combined area of ulcers >2 cm; full-thickness skin loss involving damage to or necrosis of subcutaneous tissue that may extend down to fascia Grade 3 Skin Ulceration, CTCAE Grade 3 Skin ulceration 10040947 C145621 Grade 3 Skin ulceration Grade 3 Skin ulceration Combined area of ulcers >2 cm; full-thickness skin loss involving damage to or necrosis of subcutaneous tissue that may extend down to fascia NCI Combined area of ulcers >2 cm; full-thickness skin loss involving damage to or necrosis of subcutaneous tissue that may extend down to fascia CTCAE_v5 Grade 3 Skin Ulceration, CTCAE PT NCI Grade 3 Skin ulceration PT CTCAE_v5 ctcae5:C145622 Oxygen desaturation; associated with pulmonary hypertension; medical intervention indicated; limiting self care ADL Oxygen desaturation; associated with pulmonary hypertension; medical intervention indicated; limiting self care ADL Grade 3 Sleep Apnea, CTCAE Grade 3 Sleep apnea 10040975 C145622 Grade 3 Sleep apnea Grade 3 Sleep apnea Oxygen desaturation; associated with pulmonary hypertension; medical intervention indicated; limiting self care ADL NCI Oxygen desaturation; associated with pulmonary hypertension; medical intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Sleep Apnea, CTCAE PT NCI Grade 3 Sleep apnea PT CTCAE_v5 ctcae5:C145623 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Small Intestinal Anastomotic Leak, CTCAE Grade 3 Small intestinal anastomotic leak 10065892 C145623 Grade 3 Small intestinal anastomotic leak Grade 3 Small intestinal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Small Intestinal Anastomotic Leak, CTCAE PT NCI Grade 3 Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C145624 Severe pain; interfering with oral intake; tube feeding, TPN or hospitalization indicated; limiting self care ADL Severe pain; interfering with oral intake; tube feeding, TPN or hospitalization indicated; limiting self care ADL Grade 3 Small Intestinal Mucositis, CTCAE Grade 3 Small intestinal mucositis 10065710 C145624 Grade 3 Small intestinal mucositis Grade 3 Small intestinal mucositis Severe pain; interfering with oral intake; tube feeding, TPN or hospitalization indicated; limiting self care ADL NCI Severe pain; interfering with oral intake; tube feeding, TPN or hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Small Intestinal Mucositis, CTCAE PT NCI Grade 3 Small intestinal mucositis PT CTCAE_v5 ctcae5:C145625 Hospitalization indicated; invasive intervention indicated; limiting self care ADL Hospitalization indicated; invasive intervention indicated; limiting self care ADL Grade 3 Small Intestinal Obstruction, CTCAE Grade 3 Small intestinal obstruction 10041101 C145625 Grade 3 Small intestinal obstruction Grade 3 Small intestinal obstruction Hospitalization indicated; invasive intervention indicated; limiting self care ADL NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Small Intestinal Obstruction, CTCAE PT NCI Grade 3 Small intestinal obstruction PT CTCAE_v5 ctcae5:C145626 Invasive intervention indicated Invasive intervention indicated Grade 3 Small Intestinal Perforation, CTCAE Grade 3 Small intestinal perforation 10041103 C145626 Grade 3 Small intestinal perforation Grade 3 Small intestinal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Small Intestinal Perforation, CTCAE PT NCI Grade 3 Small intestinal perforation PT CTCAE_v5 ctcae5:C145627 Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated Grade 3 Small Intestinal Stenosis, CTCAE Grade 3 Small intestinal stenosis 10062263 C145627 Grade 3 Small intestinal stenosis Grade 3 Small intestinal stenosis Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated NCI Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated CTCAE_v5 Grade 3 Small Intestinal Stenosis, CTCAE PT NCI Grade 3 Small intestinal stenosis PT CTCAE_v5 ctcae5:C145628 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Small Intestine Infection, CTCAE Grade 3 Small intestine infection 10065771 C145628 Grade 3 Small intestine infection Grade 3 Small intestine infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Small Intestine Infection, CTCAE PT NCI Grade 3 Small intestine infection PT CTCAE_v5 ctcae5:C145629 Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL Grade 3 Small Intestine Ulcer, CTCAE Grade 3 Small intestine ulcer 10041133 C145629 Grade 3 Small intestine ulcer Grade 3 Small intestine ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Small Intestine Ulcer, CTCAE PT NCI Grade 3 Small intestine ulcer PT CTCAE_v5 ctcae5:C145630 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Social Circumstances - Other, Specify, CTCAE Grade 3 Social circumstances - Other, specify 10041244 C145630 Grade 3 Social circumstances - Other, specify Grade 3 Social circumstances - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Social Circumstances - Other, Specify, CTCAE PT NCI Grade 3 Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C145631 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Soft Tissue Infection, CTCAE Grade 3 Soft tissue infection 10062255 C145631 Grade 3 Soft tissue infection Grade 3 Soft tissue infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Soft Tissue Infection, CTCAE PT NCI Grade 3 Soft tissue infection PT CTCAE_v5 ctcae5:C145632 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Soft Tissue Necrosis Lower Limb, CTCAE Grade 3 Soft tissue necrosis lower limb 10065777 C145632 Grade 3 Soft tissue necrosis lower limb Grade 3 Soft tissue necrosis lower limb Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Soft Tissue Necrosis Lower Limb, CTCAE PT NCI Grade 3 Soft tissue necrosis lower limb PT CTCAE_v5 ctcae5:C145633 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Soft Tissue Necrosis Upper Limb, CTCAE Grade 3 Soft tissue necrosis upper limb 10065778 C145633 Grade 3 Soft tissue necrosis upper limb Grade 3 Soft tissue necrosis upper limb Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Soft Tissue Necrosis Upper Limb, CTCAE PT NCI Grade 3 Soft tissue necrosis upper limb PT CTCAE_v5 ctcae5:C145634 Obtundation or stupor Obtundation or stupor Grade 3 Somnolence Grade 3 Somnolence, CTCAE 10041349 C145634 Grade 3 Somnolence Grade 3 Somnolence Obtundation or stupor NCI Obtundation or stupor CTCAE_v5 Grade 3 Somnolence PT CTCAE_v5 Grade 3 Somnolence, CTCAE PT NCI ctcae5:C145635 Severe pain; limiting self care ADL; limiting ability to swallow Severe pain; limiting self care ADL; limiting ability to swallow Grade 3 Sore Throat, CTCAE Grade 3 Sore throat 10041367 C145635 Grade 3 Sore throat Grade 3 Sore throat Severe pain; limiting self care ADL; limiting ability to swallow NCI Severe pain; limiting self care ADL; limiting ability to swallow CTCAE_v5 Grade 3 Sore Throat, CTCAE PT NCI Grade 3 Sore throat PT CTCAE_v5 ctcae5:C145636 Severe increase in muscle tone and increase in resistance through range of motion Severe increase in muscle tone and increase in resistance through range of motion Grade 3 Spasticity Grade 3 Spasticity, CTCAE 10041416 C145636 Grade 3 Spasticity Grade 3 Spasticity Severe increase in muscle tone and increase in resistance through range of motion NCI Severe increase in muscle tone and increase in resistance through range of motion CTCAE_v5 Grade 3 Spasticity PT CTCAE_v5 Grade 3 Spasticity, CTCAE PT NCI ctcae5:C145637 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Spermatic Cord Anastomotic Leak, CTCAE Grade 3 Spermatic cord anastomotic leak 10065897 C145637 Grade 3 Spermatic cord anastomotic leak Grade 3 Spermatic cord anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Grade 3 Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C145638 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Spinal Cord Compression, CTCAE Grade 3 Spinal cord compression 10041549 C145638 Grade 3 Spinal cord compression Grade 3 Spinal cord compression Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Spinal Cord Compression, CTCAE PT NCI Grade 3 Spinal cord compression PT CTCAE_v5 ctcae5:C145639 Severe back pain; hospitalization or intervention indicated for pain control (e.g., vertebroplasty); limiting self care ADL; disability Severe back pain; hospitalization or intervention indicated for pain control (e.g., vertebroplasty); limiting self care ADL; disability Grade 3 Spinal Fracture, CTCAE Grade 3 Spinal fracture 10041569 C145639 Grade 3 Spinal fracture Grade 3 Spinal fracture Severe back pain; hospitalization or intervention indicated for pain control (e.g., vertebroplasty); limiting self care ADL; disability NCI Severe back pain; hospitalization or intervention indicated for pain control (e.g., vertebroplasty); limiting self care ADL; disability CTCAE_v5 Grade 3 Spinal Fracture, CTCAE PT NCI Grade 3 Spinal fracture PT CTCAE_v5 ctcae5:C145640 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Splenic Infection, CTCAE Grade 3 Splenic infection 10062112 C145640 Grade 3 Splenic infection Grade 3 Splenic infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Splenic Infection, CTCAE PT NCI Grade 3 Splenic infection PT CTCAE_v5 ctcae5:C145641 Severely altered GI function; tube feeding, TPN or hospitalization indicated; elective operative intervention indicated Severely altered GI function; tube feeding, TPN or hospitalization indicated; elective operative intervention indicated Grade 3 Stenosis of Gastrointestinal Stoma, CTCAE Grade 3 Stenosis of gastrointestinal stoma 10065898 C145641 Grade 3 Stenosis of gastrointestinal stoma Grade 3 Stenosis of gastrointestinal stoma Severely altered GI function; tube feeding, TPN or hospitalization indicated; elective operative intervention indicated NCI Severely altered GI function; tube feeding, TPN or hospitalization indicated; elective operative intervention indicated CTCAE_v5 Grade 3 Stenosis of Gastrointestinal Stoma, CTCAE PT NCI Grade 3 Stenosis of gastrointestinal stoma PT CTCAE_v5 ctcae5:C145642 Skin sloughing covering <10% BSA with associated signs (e.g., erythema, purpura, epidermal detachment, and mucous membrane detachment) Skin sloughing covering <10% BSA with associated signs (e.g., erythema, purpura, epidermal detachment, and mucous membrane detachment) Grade 3 Stevens-Johnson Syndrome, CTCAE Grade 3 Stevens-Johnson syndrome 10042033 C145642 Grade 3 Stevens-Johnson syndrome Grade 3 Stevens-Johnson syndrome Skin sloughing covering <10% BSA with associated signs (e.g., erythema, purpura, epidermal detachment, and mucous membrane detachment) NCI Skin sloughing covering <10% BSA with associated signs (e.g., erythema, purpura, epidermal detachment, and mucous membrane detachment) CTCAE_v5 Grade 3 Stevens-Johnson Syndrome, CTCAE PT NCI Grade 3 Stevens-Johnson syndrome PT CTCAE_v5 ctcae5:C145643 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Stoma Site Infection, CTCAE Grade 3 Stoma site infection 10064505 C145643 Grade 3 Stoma site infection Grade 3 Stoma site infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Stoma Site Infection, CTCAE PT NCI Grade 3 Stoma site infection PT CTCAE_v5 ctcae5:C145644 Severe symptoms; elective operative intervention indicated Severe symptoms; elective operative intervention indicated Grade 3 Stomal Ulcer, CTCAE Grade 3 Stomal ulcer 10042127 C145644 Grade 3 Stomal ulcer Grade 3 Stomal ulcer Severe symptoms; elective operative intervention indicated NCI Severe symptoms; elective operative intervention indicated CTCAE_v5 Grade 3 Stomal Ulcer, CTCAE PT NCI Grade 3 Stomal ulcer PT CTCAE_v5 ctcae5:C145645 Respiratory distress limiting self care ADL; medical intervention indicated Respiratory distress limiting self care ADL; medical intervention indicated Grade 3 Stridor Grade 3 Stridor, CTCAE 10042241 C145645 Grade 3 Stridor Grade 3 Stridor Respiratory distress limiting self care ADL; medical intervention indicated NCI Respiratory distress limiting self care ADL; medical intervention indicated CTCAE_v5 Grade 3 Stridor PT CTCAE_v5 Grade 3 Stridor, CTCAE PT NCI ctcae5:C145646 Severe neurologic deficit; limiting self care ADL; hospitalization Severe neurologic deficit; limiting self care ADL; hospitalization Grade 3 Stroke Grade 3 Stroke, CTCAE 10042244 C145646 Grade 3 Stroke Grade 3 Stroke Severe neurologic deficit; limiting self care ADL; hospitalization NCI Severe neurologic deficit; limiting self care ADL; hospitalization CTCAE_v5 Grade 3 Stroke PT CTCAE_v5 Grade 3 Stroke, CTCAE PT NCI ctcae5:C145647 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Subcutaneous Emphysema, CTCAE Grade 3 Subcutaneous emphysema 10042344 C145647 Grade 3 Subcutaneous emphysema Grade 3 Subcutaneous emphysema Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Subcutaneous Emphysema, CTCAE PT NCI Grade 3 Subcutaneous emphysema PT CTCAE_v5 ctcae5:C145648 Specific plan to commit suicide without serious intent to die which may not require hospitalization Specific plan to commit suicide without serious intent to die which may not require hospitalization Grade 3 Suicidal Ideation, CTCAE Grade 3 Suicidal ideation 10042458 C145648 Grade 3 Suicidal ideation Grade 3 Suicidal ideation Specific plan to commit suicide without serious intent to die which may not require hospitalization NCI Specific plan to commit suicide without serious intent to die which may not require hospitalization CTCAE_v5 Grade 3 Suicidal Ideation, CTCAE PT NCI Grade 3 Suicidal ideation PT CTCAE_v5 ctcae5:C145649 Suicide attempt or gesture without intent to die Suicide attempt or gesture without intent to die Grade 3 Suicide Attempt, CTCAE Grade 3 Suicide attempt 10042464 C145649 Grade 3 Suicide attempt Grade 3 Suicide attempt Suicide attempt or gesture without intent to die NCI Suicide attempt or gesture without intent to die CTCAE_v5 Grade 3 Suicide Attempt, CTCAE PT NCI Grade 3 Suicide attempt PT CTCAE_v5 ctcae5:C145650 Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL Grade 3 Superficial Soft Tissue Fibrosis, CTCAE Grade 3 Superficial soft tissue fibrosis 10065798 C145650 Grade 3 Superficial soft tissue fibrosis Grade 3 Superficial soft tissue fibrosis Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL NCI Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self care ADL CTCAE_v5 Grade 3 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Grade 3 Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C145651 Severe symptoms; multi-modality intervention indicated (e.g., anticoagulation, chemotherapy, radiation, stenting) Severe symptoms; multi-modality intervention indicated (e.g., anticoagulation, chemotherapy, radiation, stenting) Grade 3 Superior Vena Cava Syndrome, CTCAE Grade 3 Superior vena cava syndrome 10042569 C145651 Grade 3 Superior vena cava syndrome Grade 3 Superior vena cava syndrome Severe symptoms; multi-modality intervention indicated (e.g., anticoagulation, chemotherapy, radiation, stenting) NCI Severe symptoms; multi-modality intervention indicated (e.g., anticoagulation, chemotherapy, radiation, stenting) CTCAE_v5 Grade 3 Superior Vena Cava Syndrome, CTCAE PT NCI Grade 3 Superior vena cava syndrome PT CTCAE_v5 ctcae5:C145652 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Surgical and Medical Procedures - Other, Specify, CTCAE Grade 3 Surgical and medical procedures - Other, specify 10042613 C145652 Grade 3 Surgical and medical procedures - Other, specify Grade 3 Surgical and medical procedures - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Grade 3 Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C145653 Absence of all reflexes Absence of all reflexes Grade 3 Tendon Reflex Decreased, CTCAE Grade 3 Tendon reflex decreased 10043245 C145653 Grade 3 Tendon reflex decreased Grade 3 Tendon reflex decreased Absence of all reflexes NCI Absence of all reflexes CTCAE_v5 Grade 3 Tendon Reflex Decreased, CTCAE PT NCI Grade 3 Tendon reflex decreased PT CTCAE_v5 ctcae5:C145654 Severe symptoms; interfering with sexual function; limiting self care ADL; intervention indicated Severe symptoms; interfering with sexual function; limiting self care ADL; intervention indicated Grade 3 Testicular Disorder, CTCAE Grade 3 Testicular disorder 10043306 C145654 Grade 3 Testicular disorder Grade 3 Testicular disorder Severe symptoms; interfering with sexual function; limiting self care ADL; intervention indicated NCI Severe symptoms; interfering with sexual function; limiting self care ADL; intervention indicated CTCAE_v5 Grade 3 Testicular Disorder, CTCAE PT NCI Grade 3 Testicular disorder PT CTCAE_v5 ctcae5:C145656 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Testicular Pain, CTCAE Grade 3 Testicular pain 10043345 C145656 Grade 3 Testicular pain Grade 3 Testicular pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Testicular Pain, CTCAE PT NCI Grade 3 Testicular pain PT CTCAE_v5 ctcae5:C145657 Urgent medical intervention indicated (e.g., pulmonary embolism or intracardiac thrombus) Urgent medical intervention indicated (e.g., pulmonary embolism or intracardiac thrombus) Grade 3 Thromboembolic Event, CTCAE Grade 3 Thromboembolic event 10043565 C145657 Grade 3 Thromboembolic event Grade 3 Thromboembolic event Urgent medical intervention indicated (e.g., pulmonary embolism or intracardiac thrombus) NCI Urgent medical intervention indicated (e.g., pulmonary embolism or intracardiac thrombus) CTCAE_v5 Grade 3 Thromboembolic Event, CTCAE PT NCI Grade 3 Thromboembolic event PT CTCAE_v5 ctcae5:C145658 Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) Grade 3 Thrombotic Thrombocytopenic Purpura, CTCAE Grade 3 Thrombotic thrombocytopenic purpura 10043648 C145658 Grade 3 Thrombotic thrombocytopenic purpura Grade 3 Thrombotic thrombocytopenic purpura Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) NCI Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae) CTCAE_v5 Grade 3 Thrombotic Thrombocytopenic Purpura, CTCAE PT NCI Grade 3 Thrombotic thrombocytopenic purpura PT CTCAE_v5 ctcae5:C145659 IV antifungal intervention indicated IV antifungal intervention indicated Grade 3 Thrush Grade 3 Thrush, CTCAE 10043649 C145659 Grade 3 Thrush Grade 3 Thrush IV antifungal intervention indicated NCI IV antifungal intervention indicated CTCAE_v5 Grade 3 Thrush PT CTCAE_v5 Grade 3 Thrush, CTCAE PT NCI ctcae5:C145660 Maldevelopment with impairment not surgically correctable; limiting self care ADL Maldevelopment with impairment not surgically correctable; limiting self care ADL Grade 3 Tooth Development Disorder, CTCAE Grade 3 Tooth development disorder 10044030 C145660 Grade 3 Tooth development disorder Grade 3 Tooth development disorder Maldevelopment with impairment not surgically correctable; limiting self care ADL NCI Maldevelopment with impairment not surgically correctable; limiting self care ADL CTCAE_v5 Grade 3 Tooth Development Disorder, CTCAE PT NCI Grade 3 Tooth development disorder PT CTCAE_v5 ctcae5:C145661 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Tooth Infection, CTCAE Grade 3 Tooth infection 10048762 C145661 Grade 3 Tooth infection Grade 3 Tooth infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Tooth Infection, CTCAE PT NCI Grade 3 Tooth infection PT CTCAE_v5 ctcae5:C145662 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Toothache Grade 3 Toothache, CTCAE 10044055 C145662 Grade 3 Toothache Grade 3 Toothache Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Toothache PT CTCAE_v5 Grade 3 Toothache, CTCAE PT NCI ctcae5:C145665 Severe pain; hemorrhage or respiratory symptoms; limiting self care ADL Severe pain; hemorrhage or respiratory symptoms; limiting self care ADL Grade 3 Tracheal Mucositis, CTCAE Grade 3 Tracheal mucositis 10065900 C145665 Grade 3 Tracheal mucositis Grade 3 Tracheal mucositis Severe pain; hemorrhage or respiratory symptoms; limiting self care ADL NCI Severe pain; hemorrhage or respiratory symptoms; limiting self care ADL CTCAE_v5 Grade 3 Tracheal Mucositis, CTCAE PT NCI Grade 3 Tracheal mucositis PT CTCAE_v5 ctcae5:C145666 Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) Grade 3 Tracheal Obstruction, CTCAE Grade 3 Tracheal obstruction 10044291 C145666 Grade 3 Tracheal obstruction Grade 3 Tracheal obstruction Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) NCI Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Tracheal Obstruction, CTCAE PT NCI Grade 3 Tracheal obstruction PT CTCAE_v5 ctcae5:C145667 Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) Grade 3 Tracheal Stenosis, CTCAE Grade 3 Tracheal stenosis 10050816 C145667 Grade 3 Tracheal stenosis Grade 3 Tracheal stenosis Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) NCI Stridor or respiratory distress limiting self care ADL; invasive intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Tracheal Stenosis, CTCAE PT NCI Grade 3 Tracheal stenosis PT CTCAE_v5 ctcae5:C145668 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Tracheitis Grade 3 Tracheitis, CTCAE 10044302 C145668 Grade 3 Tracheitis Grade 3 Tracheitis IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Tracheitis PT CTCAE_v5 Grade 3 Tracheitis, CTCAE PT NCI ctcae5:C145669 Transfusion indicated; invasive intervention indicated Transfusion indicated; invasive intervention indicated Grade 3 Tracheostomy Site Bleeding, CTCAE Grade 3 Tracheostomy site bleeding 10065749 C145669 Grade 3 Tracheostomy site bleeding Grade 3 Tracheostomy site bleeding Transfusion indicated; invasive intervention indicated NCI Transfusion indicated; invasive intervention indicated CTCAE_v5 Grade 3 Tracheostomy Site Bleeding, CTCAE PT NCI Grade 3 Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C145670 Non life-threatening secondary malignancy Non life-threatening secondary malignancy Grade 3 Treatment Related Secondary Malignancy, CTCAE Grade 3 Treatment related secondary malignancy 10049737 C145670 Grade 3 Treatment related secondary malignancy Grade 3 Treatment related secondary malignancy Non life-threatening secondary malignancy NCI Non life-threatening secondary malignancy CTCAE_v5 Grade 3 Treatment Related Secondary Malignancy, CTCAE PT NCI Grade 3 Treatment related secondary malignancy PT CTCAE_v5 ctcae5:C145671 Symptomatic; severe regurgitation or stenosis; symptoms controlled with medical intervention Symptomatic; severe regurgitation or stenosis; symptoms controlled with medical intervention Grade 3 Tricuspid Valve Disease, CTCAE Grade 3 Tricuspid valve disease 10061389 C145671 Grade 3 Tricuspid valve disease Grade 3 Tricuspid valve disease Symptomatic; severe regurgitation or stenosis; symptoms controlled with medical intervention NCI Symptomatic; severe regurgitation or stenosis; symptoms controlled with medical intervention CTCAE_v5 Grade 3 Tricuspid Valve Disease, CTCAE PT NCI Grade 3 Tricuspid valve disease PT CTCAE_v5 ctcae5:C145672 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Trigeminal Nerve Disorder, CTCAE Grade 3 Trigeminal nerve disorder 10060890 C145672 Grade 3 Trigeminal nerve disorder Grade 3 Trigeminal nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Trigeminal Nerve Disorder, CTCAE PT NCI Grade 3 Trigeminal nerve disorder PT CTCAE_v5 ctcae5:C145673 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Trochlear Nerve Disorder, CTCAE Grade 3 Trochlear nerve disorder 10074765 C145673 Grade 3 Trochlear nerve disorder Grade 3 Trochlear nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Trochlear Nerve Disorder, CTCAE PT NCI Grade 3 Trochlear nerve disorder PT CTCAE_v5 ctcae5:C145674 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Tumor Hemorrhage, CTCAE Grade 3 Tumor hemorrhage 10055351 C145674 Grade 3 Tumor hemorrhage Grade 3 Tumor hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Tumor Hemorrhage, CTCAE PT NCI Grade 3 Tumor hemorrhage PT CTCAE_v5 ctcae5:C145675 Severe length discrepancy >5 cm; limiting self care ADL; operative intervention indicated Severe length discrepancy >5 cm; limiting self care ADL; operative intervention indicated Grade 3 Unequal Limb Length, CTCAE Grade 3 Unequal limb length 10065738 C145675 Grade 3 Unequal limb length Grade 3 Unequal limb length Severe length discrepancy >5 cm; limiting self care ADL; operative intervention indicated NCI Severe length discrepancy >5 cm; limiting self care ADL; operative intervention indicated CTCAE_v5 Grade 3 Unequal Limb Length, CTCAE PT NCI Grade 3 Unequal limb length PT CTCAE_v5 ctcae5:C145676 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Upper Gastrointestinal Hemorrhage, CTCAE Grade 3 Upper gastrointestinal hemorrhage 10055356 C145676 Grade 3 Upper gastrointestinal hemorrhage Grade 3 Upper gastrointestinal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 3 Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C145677 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Upper Respiratory Infection, CTCAE Grade 3 Upper respiratory infection 10046300 C145677 Grade 3 Upper respiratory infection Grade 3 Upper respiratory infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Upper Respiratory Infection, CTCAE PT NCI Grade 3 Upper respiratory infection PT CTCAE_v5 ctcae5:C145678 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Ureteric Anastomotic Leak, CTCAE Grade 3 Ureteric anastomotic leak 10065814 C145678 Grade 3 Ureteric anastomotic leak Grade 3 Ureteric anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Ureteric Anastomotic Leak, CTCAE PT NCI Grade 3 Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C145679 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Urethral Anastomotic Leak, CTCAE Grade 3 Urethral anastomotic leak 10065815 C145679 Grade 3 Urethral anastomotic leak Grade 3 Urethral anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Urethral Anastomotic Leak, CTCAE PT NCI Grade 3 Urethral anastomotic leak PT CTCAE_v5 ctcae5:C145680 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Urethral Infection, CTCAE Grade 3 Urethral infection 10052298 C145680 Grade 3 Urethral infection Grade 3 Urethral infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Urethral Infection, CTCAE PT NCI Grade 3 Urethral infection PT CTCAE_v5 ctcae5:C145681 Invasive intervention indicated Invasive intervention indicated Grade 3 Urinary Fistula, CTCAE Grade 3 Urinary fistula 10065368 C145681 Grade 3 Urinary fistula Grade 3 Urinary fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Urinary Fistula, CTCAE PT NCI Grade 3 Urinary fistula PT CTCAE_v5 ctcae5:C145682 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Urinary Tract Infection, CTCAE Grade 3 Urinary tract infection 10046571 C145682 Grade 3 Urinary tract infection Grade 3 Urinary tract infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Urinary Tract Infection, CTCAE PT NCI Grade 3 Urinary tract infection PT CTCAE_v5 ctcae5:C145683 Altered organ function (e.g., hydronephrosis or renal dysfunction); invasive intervention indicated Altered organ function (e.g., hydronephrosis or renal dysfunction); invasive intervention indicated Grade 3 Urinary Tract Obstruction, CTCAE Grade 3 Urinary tract obstruction 10061574 C145683 Grade 3 Urinary tract obstruction Grade 3 Urinary tract obstruction Altered organ function (e.g., hydronephrosis or renal dysfunction); invasive intervention indicated NCI Altered organ function (e.g., hydronephrosis or renal dysfunction); invasive intervention indicated CTCAE_v5 Grade 3 Urinary Tract Obstruction, CTCAE PT NCI Grade 3 Urinary tract obstruction PT CTCAE_v5 ctcae5:C145684 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Urinary Tract Pain, CTCAE Grade 3 Urinary tract pain 10062225 C145684 Grade 3 Urinary tract pain Grade 3 Urinary tract pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Urinary Tract Pain, CTCAE PT NCI Grade 3 Urinary tract pain PT CTCAE_v5 ctcae5:C145685 Adult: Oliguria (<80 ml in 8 hr); Infants: < 0.5 mL/kg per hour for 24 hours; Children: < 500 mL/1.73 m2 body surface area per day Adult: Oliguria (<80 ml in 8 hr); Infants: < 0.5 mL/kg per hour for 24 hours; Children: < 500 mL/1.73 m2 body surface area per day Grade 3 Urine Output Decreased, CTCAE Grade 3 Urine output decreased 10059895 C145685 Grade 3 Urine output decreased Grade 3 Urine output decreased Adult: Oliguria (<80 ml in 8 hr); Infants: < 0.5 mL/kg per hour for 24 hours; Children: < 500 mL/1.73 m2 body surface area per day NCI Adult: Oliguria (<80 ml in 8 hr); Infants: < 0.5 mL/kg per hour for 24 hours; Children: < 500 mL/1.73 m2 body surface area per day CTCAE_v5 Grade 3 Urine Output Decreased, CTCAE PT NCI Grade 3 Urine output decreased PT CTCAE_v5 ctcae5:C145686 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Urostomy Leak, CTCAE Grade 3 Urostomy leak 10065882 C145686 Grade 3 Urostomy leak Grade 3 Urostomy leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Urostomy Leak, CTCAE PT NCI Grade 3 Urostomy leak PT CTCAE_v5 ctcae5:C145687 Altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); elective operative intervention indicated Altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); elective operative intervention indicated Grade 3 Urostomy Obstruction, CTCAE Grade 3 Urostomy obstruction 10065883 C145687 Grade 3 Urostomy obstruction Grade 3 Urostomy obstruction Altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); elective operative intervention indicated NCI Altered organ function (e.g., sepsis or hydronephrosis, or renal dysfunction); elective operative intervention indicated CTCAE_v5 Grade 3 Urostomy Obstruction, CTCAE PT NCI Grade 3 Urostomy obstruction PT CTCAE_v5 ctcae5:C145688 Transfusion indicated; invasive intervention indicated Transfusion indicated; invasive intervention indicated Grade 3 Urostomy Site Bleeding, CTCAE Grade 3 Urostomy site bleeding 10065748 C145688 Grade 3 Urostomy site bleeding Grade 3 Urostomy site bleeding Transfusion indicated; invasive intervention indicated NCI Transfusion indicated; invasive intervention indicated CTCAE_v5 Grade 3 Urostomy Site Bleeding, CTCAE PT NCI Grade 3 Urostomy site bleeding PT CTCAE_v5 ctcae5:C145689 Symptomatic (e.g., hydronephrosis, or renal dysfunction); elective operative intervention indicated Symptomatic (e.g., hydronephrosis, or renal dysfunction); elective operative intervention indicated Grade 3 Urostomy Stenosis, CTCAE Grade 3 Urostomy stenosis 10065885 C145689 Grade 3 Urostomy stenosis Grade 3 Urostomy stenosis Symptomatic (e.g., hydronephrosis, or renal dysfunction); elective operative intervention indicated NCI Symptomatic (e.g., hydronephrosis, or renal dysfunction); elective operative intervention indicated CTCAE_v5 Grade 3 Urostomy Stenosis, CTCAE PT NCI Grade 3 Urostomy stenosis PT CTCAE_v5 ctcae5:C145690 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Uterine Anastomotic Leak, CTCAE Grade 3 Uterine anastomotic leak 10065886 C145690 Grade 3 Uterine anastomotic leak Grade 3 Uterine anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Uterine Anastomotic Leak, CTCAE PT NCI Grade 3 Uterine anastomotic leak PT CTCAE_v5 ctcae5:C145691 Invasive intervention indicated Invasive intervention indicated Grade 3 Uterine Fistula, CTCAE Grade 3 Uterine fistula 10065811 C145691 Grade 3 Uterine fistula Grade 3 Uterine fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Uterine Fistula, CTCAE PT NCI Grade 3 Uterine fistula PT CTCAE_v5 ctcae5:C145693 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Uterine Infection, CTCAE Grade 3 Uterine infection 10062233 C145693 Grade 3 Uterine infection Grade 3 Uterine infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Uterine Infection, CTCAE PT NCI Grade 3 Uterine infection PT CTCAE_v5 ctcae5:C145694 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Uterine Obstruction, CTCAE Grade 3 Uterine obstruction 10065928 C145694 Grade 3 Uterine obstruction Grade 3 Uterine obstruction Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Uterine Obstruction, CTCAE PT NCI Grade 3 Uterine obstruction PT CTCAE_v5 ctcae5:C145695 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Uterine Pain, CTCAE Grade 3 Uterine pain 10046809 C145695 Grade 3 Uterine pain Grade 3 Uterine pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Uterine Pain, CTCAE PT NCI Grade 3 Uterine pain PT CTCAE_v5 ctcae5:C145696 Invasive intervention indicated Invasive intervention indicated Grade 3 Uterine Perforation, CTCAE Grade 3 Uterine perforation 10046810 C145696 Grade 3 Uterine perforation Grade 3 Uterine perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Uterine Perforation, CTCAE PT NCI Grade 3 Uterine perforation PT CTCAE_v5 ctcae5:C145697 Severe pain; Erythema > 10 cm; Induration/swelling > 10 cm; necrosis; limiting self care ADL Severe pain; Erythema > 10 cm; Induration/swelling > 10 cm; necrosis; limiting self care ADL Grade 3 Vaccination Complication, CTCAE Grade 3 Vaccination complication 10046861 C145697 Grade 3 Vaccination complication Grade 3 Vaccination complication Severe pain; Erythema > 10 cm; Induration/swelling > 10 cm; necrosis; limiting self care ADL NCI Severe pain; Erythema > 10 cm; Induration/swelling > 10 cm; necrosis; limiting self care ADL CTCAE_v5 Grade 3 Vaccination Complication, CTCAE PT NCI Grade 3 Vaccination complication PT CTCAE_v5 ctcae5:C145698 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Vaginal Anastomotic Leak, CTCAE Grade 3 Vaginal anastomotic leak 10065887 C145698 Grade 3 Vaginal anastomotic leak Grade 3 Vaginal anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Vaginal Anastomotic Leak, CTCAE PT NCI Grade 3 Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C145699 Severe vaginal dryness resulting in dyspareunia or severe discomfort Severe vaginal dryness resulting in dyspareunia or severe discomfort Grade 3 Vaginal Dryness, CTCAE Grade 3 Vaginal dryness 10046904 C145699 Grade 3 Vaginal dryness Grade 3 Vaginal dryness Severe vaginal dryness resulting in dyspareunia or severe discomfort NCI Severe vaginal dryness resulting in dyspareunia or severe discomfort CTCAE_v5 Grade 3 Vaginal Dryness, CTCAE PT NCI Grade 3 Vaginal dryness PT CTCAE_v5 ctcae5:C145702 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Vaginal Infection, CTCAE Grade 3 Vaginal infection 10046914 C145702 Grade 3 Vaginal infection Grade 3 Vaginal infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Vaginal Infection, CTCAE PT NCI Grade 3 Vaginal infection PT CTCAE_v5 ctcae5:C145703 Severe discomfort or pain, edema, or redness; limiting self care ADL; small areas of mucosal ulceration Severe discomfort or pain, edema, or redness; limiting self care ADL; small areas of mucosal ulceration Grade 3 Vaginal Inflammation, CTCAE Grade 3 Vaginal inflammation 10046916 C145703 Grade 3 Vaginal inflammation Grade 3 Vaginal inflammation Severe discomfort or pain, edema, or redness; limiting self care ADL; small areas of mucosal ulceration NCI Severe discomfort or pain, edema, or redness; limiting self care ADL; small areas of mucosal ulceration CTCAE_v5 Grade 3 Vaginal Inflammation, CTCAE PT NCI Grade 3 Vaginal inflammation PT CTCAE_v5 ctcae5:C145704 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Vaginal Obstruction, CTCAE Grade 3 Vaginal obstruction 10065817 C145704 Grade 3 Vaginal obstruction Grade 3 Vaginal obstruction Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Vaginal Obstruction, CTCAE PT NCI Grade 3 Vaginal obstruction PT CTCAE_v5 ctcae5:C145705 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Vaginal Pain, CTCAE Grade 3 Vaginal pain 10046937 C145705 Grade 3 Vaginal pain Grade 3 Vaginal pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Vaginal Pain, CTCAE PT NCI Grade 3 Vaginal pain PT CTCAE_v5 ctcae5:C145706 Invasive intervention indicated Invasive intervention indicated Grade 3 Vaginal Perforation, CTCAE Grade 3 Vaginal perforation 10065818 C145706 Grade 3 Vaginal perforation Grade 3 Vaginal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Vaginal Perforation, CTCAE PT NCI Grade 3 Vaginal perforation PT CTCAE_v5 ctcae5:C145707 Vaginal narrowing and/or shortening interfering with the use of tampons, sexual activity or physical examination Vaginal narrowing and/or shortening interfering with the use of tampons, sexual activity or physical examination Grade 3 Vaginal Stricture, CTCAE Grade 3 Vaginal stricture 10053496 C145707 Grade 3 Vaginal stricture Grade 3 Vaginal stricture Vaginal narrowing and/or shortening interfering with the use of tampons, sexual activity or physical examination NCI Vaginal narrowing and/or shortening interfering with the use of tampons, sexual activity or physical examination CTCAE_v5 Grade 3 Vaginal Stricture, CTCAE PT NCI Grade 3 Vaginal stricture PT CTCAE_v5 ctcae5:C145708 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Vagus Nerve Disorder, CTCAE Grade 3 Vagus nerve disorder 10061403 C145708 Grade 3 Vagus nerve disorder Grade 3 Vagus nerve disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Vagus Nerve Disorder, CTCAE PT NCI Grade 3 Vagus nerve disorder PT CTCAE_v5 ctcae5:C145709 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Vas Deferens Anastomotic Leak, CTCAE Grade 3 Vas deferens anastomotic leak 10065888 C145709 Grade 3 Vas deferens anastomotic leak Grade 3 Vas deferens anastomotic leak Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Vas Deferens Anastomotic Leak, CTCAE PT NCI Grade 3 Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C145710 Pulmonary embolism, deep vein or cardiac thrombosis; intervention indicated (e.g., anticoagulation, lysis, filter, invasive procedure) Pulmonary embolism, deep vein or cardiac thrombosis; intervention indicated (e.g., anticoagulation, lysis, filter, invasive procedure) Grade 3 Vascular Access Complication, CTCAE Grade 3 Vascular access complication 10062169 C145710 Grade 3 Vascular access complication Grade 3 Vascular access complication Pulmonary embolism, deep vein or cardiac thrombosis; intervention indicated (e.g., anticoagulation, lysis, filter, invasive procedure) NCI Pulmonary embolism, deep vein or cardiac thrombosis; intervention indicated (e.g., anticoagulation, lysis, filter, invasive procedure) CTCAE_v5 Grade 3 Vascular Access Complication, CTCAE PT NCI Grade 3 Vascular access complication PT CTCAE_v5 ctcae5:C145711 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL Grade 3 Vascular Disorders - Other, Specify, CTCAE Grade 3 Vascular disorders - Other, specify 10047065 C145711 Grade 3 Vascular disorders - Other, specify Grade 3 Vascular disorders - Other, specify Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care ADL CTCAE_v5 Grade 3 Vascular Disorders - Other, Specify, CTCAE PT NCI Grade 3 Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C145712 Present Present Grade 3 Vasovagal Reaction, CTCAE Grade 3 Vasovagal reaction 10047166 C145712 Grade 3 Vasovagal reaction Grade 3 Vasovagal reaction Present NCI Present CTCAE_v5 Grade 3 Vasovagal Reaction, CTCAE PT NCI Grade 3 Vasovagal reaction PT CTCAE_v5 ctcae5:C145713 Severe symptoms; limiting self care ADL; repair or revision indicated Severe symptoms; limiting self care ADL; repair or revision indicated Grade 3 Venous Injury, CTCAE Grade 3 Venous injury 10047228 C145713 Grade 3 Venous injury Grade 3 Venous injury Severe symptoms; limiting self care ADL; repair or revision indicated NCI Severe symptoms; limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Venous Injury, CTCAE PT NCI Grade 3 Venous injury PT CTCAE_v5 ctcae5:C145714 Urgent intervention indicated Urgent intervention indicated Grade 3 Ventricular Arrhythmia, CTCAE Grade 3 Ventricular arrhythmia 10047281 C145714 Grade 3 Ventricular arrhythmia Grade 3 Ventricular arrhythmia Urgent intervention indicated NCI Urgent intervention indicated CTCAE_v5 Grade 3 Ventricular Arrhythmia, CTCAE PT NCI Grade 3 Ventricular arrhythmia PT CTCAE_v5 ctcae5:C145715 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Vertigo Grade 3 Vertigo, CTCAE 10047340 C145715 Grade 3 Vertigo Grade 3 Vertigo Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Vertigo PT CTCAE_v5 Grade 3 Vertigo, CTCAE PT NCI ctcae5:C145716 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Vestibular Disorder, CTCAE Grade 3 Vestibular disorder 10047386 C145716 Grade 3 Vestibular disorder Grade 3 Vestibular disorder Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Vestibular Disorder, CTCAE PT NCI Grade 3 Vestibular disorder PT CTCAE_v5 ctcae5:C145717 Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated Grade 3 Viremia Grade 3 Viremia, CTCAE 10054688 C145717 Grade 3 Viremia Grade 3 Viremia Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated NCI Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated CTCAE_v5 Grade 3 Viremia PT CTCAE_v5 Grade 3 Viremia, CTCAE PT NCI ctcae5:C145718 Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated Grade 3 Visceral Arterial Ischemia, CTCAE Grade 3 Visceral arterial ischemia 10054692 C145718 Grade 3 Visceral arterial ischemia Grade 3 Visceral arterial ischemia Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated NCI Prolonged (>=24 hrs) or recurring symptoms and/or invasive intervention indicated CTCAE_v5 Grade 3 Visceral Arterial Ischemia, CTCAE PT NCI Grade 3 Visceral arterial ischemia PT CTCAE_v5 ctcae5:C145719 Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Grade 3 Vision Decreased, CTCAE Grade 3 Vision decreased 10047516 C145719 Grade 3 Vision decreased Grade 3 Vision decreased Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) NCI Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) CTCAE_v5 Grade 3 Vision Decreased, CTCAE PT NCI Grade 3 Vision decreased PT CTCAE_v5 ctcae5:C145720 <50% of predicted value; limiting self care ADL <50% of predicted value; limiting self care ADL Grade 3 Vital Capacity Abnormal, CTCAE Grade 3 Vital capacity abnormal 10047580 C145720 Grade 3 Vital capacity abnormal Grade 3 Vital capacity abnormal <50% of predicted value; limiting self care ADL NCI <50% of predicted value; limiting self care ADL CTCAE_v5 Grade 3 Vital Capacity Abnormal, CTCAE PT NCI Grade 3 Vital capacity abnormal PT CTCAE_v5 ctcae5:C145721 Severe voice changes including predominantly whispered speech; may require frequent repetition or face-to-face contact for understandability; may require assistive technology Severe voice changes including predominantly whispered speech; may require frequent repetition or face-to-face contact for understandability; may require assistive technology Grade 3 Voice Alteration, CTCAE Grade 3 Voice alteration 10047681 C145721 Grade 3 Voice alteration Grade 3 Voice alteration Severe voice changes including predominantly whispered speech; may require frequent repetition or face-to-face contact for understandability; may require assistive technology NCI Severe voice changes including predominantly whispered speech; may require frequent repetition or face-to-face contact for understandability; may require assistive technology CTCAE_v5 Grade 3 Voice Alteration, CTCAE PT NCI Grade 3 Voice alteration PT CTCAE_v5 ctcae5:C145722 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Vulval Infection, CTCAE Grade 3 Vulval infection 10065772 C145722 Grade 3 Vulval infection Grade 3 Vulval infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Vulval Infection, CTCAE PT NCI Grade 3 Vulval infection PT CTCAE_v5 ctcae5:C145723 Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) Grade 3 Watering Eyes, CTCAE Grade 3 Watering eyes 10047848 C145723 Grade 3 Watering eyes Grade 3 Watering eyes Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) NCI Marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) CTCAE_v5 Grade 3 Watering Eyes, CTCAE PT NCI Grade 3 Watering eyes PT CTCAE_v5 ctcae5:C145724 Severe respiratory symptoms limiting self care ADL; oxygen therapy or hospitalization indicated Severe respiratory symptoms limiting self care ADL; oxygen therapy or hospitalization indicated Grade 3 Wheezing Grade 3 Wheezing, CTCAE 10047924 C145724 Grade 3 Wheezing Grade 3 Wheezing Severe respiratory symptoms limiting self care ADL; oxygen therapy or hospitalization indicated NCI Severe respiratory symptoms limiting self care ADL; oxygen therapy or hospitalization indicated CTCAE_v5 Grade 3 Wheezing PT CTCAE_v5 Grade 3 Wheezing, CTCAE PT NCI ctcae5:C145725 <2000-1000/mm3; <2.0-1.0 x 10e9/L <2000-1000/mm3; <2.0-1.0 x 10e9/L Grade 3 White Blood Cell Decreased, CTCAE Grade 3 White blood cell decreased 10049182 C145725 Grade 3 White blood cell decreased Grade 3 White blood cell decreased <2000-1000/mm3; <2.0-1.0 x 10e9/L NCI <2000-1000/mm3; <2.0-1.0 x 10e9/L CTCAE_v5 Grade 3 White Blood Cell Decreased, CTCAE PT NCI Grade 3 White blood cell decreased PT CTCAE_v5 ctcae5:C145726 Operative intervention indicated Operative intervention indicated Grade 3 Wound Complication, CTCAE Grade 3 Wound complication 10053692 C145726 Grade 3 Wound complication Grade 3 Wound complication Operative intervention indicated NCI Operative intervention indicated CTCAE_v5 Grade 3 Wound Complication, CTCAE PT NCI Grade 3 Wound complication PT CTCAE_v5 ctcae5:C145727 Fascial disruption or dehiscence without evisceration; revision by operative intervention indicated Fascial disruption or dehiscence without evisceration; revision by operative intervention indicated Grade 3 Wound Dehiscence, CTCAE Grade 3 Wound dehiscence 10048031 C145727 Grade 3 Wound dehiscence Grade 3 Wound dehiscence Fascial disruption or dehiscence without evisceration; revision by operative intervention indicated NCI Fascial disruption or dehiscence without evisceration; revision by operative intervention indicated CTCAE_v5 Grade 3 Wound Dehiscence, CTCAE PT NCI Grade 3 Wound dehiscence PT CTCAE_v5 ctcae5:C145728 IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated Grade 3 Wound Infection, CTCAE Grade 3 Wound infection 10048038 C145728 Grade 3 Wound infection Grade 3 Wound infection IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated NCI IV antibiotic, antifungal, or antiviral intervention indicated; invasive intervention indicated CTCAE_v5 Grade 3 Wound Infection, CTCAE PT NCI Grade 3 Wound infection PT CTCAE_v5 ctcae5:C145729 Limiting self care ADL; elective operative intervention indicated requiring hospitalization Limiting self care ADL; elective operative intervention indicated requiring hospitalization Grade 3 Wrist Fracture, CTCAE Grade 3 Wrist fracture 10048049 C145729 Grade 3 Wrist fracture Grade 3 Wrist fracture Limiting self care ADL; elective operative intervention indicated requiring hospitalization NCI Limiting self care ADL; elective operative intervention indicated requiring hospitalization CTCAE_v5 Grade 3 Wrist Fracture, CTCAE PT NCI Grade 3 Wrist fracture PT CTCAE_v5 ctcae5:C145730 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Abdominal Infection, CTCAE Grade 4 Abdominal infection 10056519 C145730 Grade 4 Abdominal infection Grade 4 Abdominal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Abdominal Infection, CTCAE PT NCI Grade 4 Abdominal infection PT CTCAE_v5 ctcae5:C145731 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Abdominal Soft Tissue Necrosis, CTCAE Grade 4 Abdominal soft tissue necrosis 10065775 C145731 Grade 4 Abdominal soft tissue necrosis Grade 4 Abdominal soft tissue necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Abdominal Soft Tissue Necrosis, CTCAE PT NCI Grade 4 Abdominal soft tissue necrosis PT CTCAE_v5 ctcae5:C145732 Life-threatening consequences Life-threatening consequences Grade 4 Acidosis Grade 4 Acidosis, CTCAE 10000486 C145732 Grade 4 Acidosis Grade 4 Acidosis Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Acidosis PT CTCAE_v5 Grade 4 Acidosis, CTCAE PT NCI ctcae5:C145733 Life-threatening consequences; dialysis indicated Life-threatening consequences; dialysis indicated Grade 4 Acute Kidney Injury, CTCAE Grade 4 Acute kidney injury 10069339 C145733 Grade 4 Acute kidney injury Grade 4 Acute kidney injury Life-threatening consequences; dialysis indicated NCI Life-threatening consequences; dialysis indicated CTCAE_v5 Grade 4 Acute Kidney Injury, CTCAE PT NCI Grade 4 Acute kidney injury PT CTCAE_v5 ctcae5:C145734 >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal Grade 4 Alanine Aminotransferase Increased, CTCAE Grade 4 Alanine aminotransferase increased 10001551 C145734 Grade 4 Alanine aminotransferase increased Grade 4 Alanine aminotransferase increased >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal NCI >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 4 Alanine Aminotransferase Increased, CTCAE PT NCI Grade 4 Alanine aminotransferase increased PT CTCAE_v5 ctcae5:C145735 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Alcohol Intolerance, CTCAE Grade 4 Alcohol intolerance 10001598 C145735 Grade 4 Alcohol intolerance Grade 4 Alcohol intolerance Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Alcohol Intolerance, CTCAE PT NCI Grade 4 Alcohol intolerance PT CTCAE_v5 ctcae5:C145736 >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal Grade 4 Alkaline Phosphatase Increased, CTCAE Grade 4 Alkaline phosphatase increased 10001675 C145736 Grade 4 Alkaline phosphatase increased Grade 4 Alkaline phosphatase increased >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal NCI >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 4 Alkaline Phosphatase Increased, CTCAE PT NCI Grade 4 Alkaline phosphatase increased PT CTCAE_v5 ctcae5:C145737 Life-threatening consequences Life-threatening consequences Grade 4 Alkalosis Grade 4 Alkalosis, CTCAE 10001680 C145737 Grade 4 Alkalosis Grade 4 Alkalosis Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Alkalosis PT CTCAE_v5 Grade 4 Alkalosis, CTCAE PT NCI ctcae5:C145738 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Allergic Reaction, CTCAE Grade 4 Allergic reaction 10001718 C145738 Grade 4 Allergic reaction Grade 4 Allergic reaction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Allergic Reaction, CTCAE PT NCI Grade 4 Allergic reaction PT CTCAE_v5 ctcae5:C145739 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anal Fistula, CTCAE Grade 4 Anal fistula 10002156 C145739 Grade 4 Anal fistula Grade 4 Anal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anal Fistula, CTCAE PT NCI Grade 4 Anal fistula PT CTCAE_v5 ctcae5:C145740 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anal Hemorrhage, CTCAE Grade 4 Anal hemorrhage 10055226 C145740 Grade 4 Anal hemorrhage Grade 4 Anal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anal Hemorrhage, CTCAE PT NCI Grade 4 Anal hemorrhage PT CTCAE_v5 ctcae5:C145741 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Anal Necrosis, CTCAE Grade 4 Anal necrosis 10065722 C145741 Grade 4 Anal necrosis Grade 4 Anal necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Anal Necrosis, CTCAE PT NCI Grade 4 Anal necrosis PT CTCAE_v5 ctcae5:C145742 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Anal Stenosis, CTCAE Grade 4 Anal stenosis 10002176 C145742 Grade 4 Anal stenosis Grade 4 Anal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Anal Stenosis, CTCAE PT NCI Grade 4 Anal stenosis PT CTCAE_v5 ctcae5:C145743 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Anal Ulcer, CTCAE Grade 4 Anal ulcer 10002180 C145743 Grade 4 Anal ulcer Grade 4 Anal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Anal Ulcer, CTCAE PT NCI Grade 4 Anal ulcer PT CTCAE_v5 ctcae5:C145744 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anaphylaxis Grade 4 Anaphylaxis, CTCAE 10002218 C145744 Grade 4 Anaphylaxis Grade 4 Anaphylaxis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anaphylaxis PT CTCAE_v5 Grade 4 Anaphylaxis, CTCAE PT NCI ctcae5:C145745 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anemia Grade 4 Anemia, CTCAE 10002272 C145745 Grade 4 Anemia Grade 4 Anemia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anemia PT CTCAE_v5 Grade 4 Anemia, CTCAE PT NCI ctcae5:C145746 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anorectal Infection, CTCAE Grade 4 Anorectal infection 10061640 C145746 Grade 4 Anorectal infection Grade 4 Anorectal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anorectal Infection, CTCAE PT NCI Grade 4 Anorectal infection PT CTCAE_v5 ctcae5:C145747 Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Grade 4 Aortic Injury, CTCAE Grade 4 Aortic injury 10002899 C145747 Grade 4 Aortic injury Grade 4 Aortic injury Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated NCI Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated CTCAE_v5 Grade 4 Aortic Injury, CTCAE PT NCI Grade 4 Aortic injury PT CTCAE_v5 ctcae5:C145748 Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Grade 4 Aortic Valve Disease, CTCAE Grade 4 Aortic valve disease 10061589 C145748 Grade 4 Aortic valve disease Grade 4 Aortic valve disease Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) NCI Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) CTCAE_v5 Grade 4 Aortic Valve Disease, CTCAE PT NCI Grade 4 Aortic valve disease PT CTCAE_v5 ctcae5:C145749 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Appendicitis Perforated, CTCAE Grade 4 Appendicitis perforated 10003012 C145749 Grade 4 Appendicitis perforated Grade 4 Appendicitis perforated Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Appendicitis Perforated, CTCAE PT NCI Grade 4 Appendicitis perforated PT CTCAE_v5 ctcae5:C145750 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Appendicitis Grade 4 Appendicitis, CTCAE 10003011 C145750 Grade 4 Appendicitis Grade 4 Appendicitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Appendicitis PT CTCAE_v5 Grade 4 Appendicitis, CTCAE PT NCI ctcae5:C145751 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Arachnoiditis Grade 4 Arachnoiditis, CTCAE 10003074 C145751 Grade 4 Arachnoiditis Grade 4 Arachnoiditis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Arachnoiditis PT CTCAE_v5 Grade 4 Arachnoiditis, CTCAE PT NCI ctcae5:C145752 Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Grade 4 Arterial Injury, CTCAE Grade 4 Arterial injury 10003162 C145752 Grade 4 Arterial injury Grade 4 Arterial injury Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated NCI Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated CTCAE_v5 Grade 4 Arterial Injury, CTCAE PT NCI Grade 4 Arterial injury PT CTCAE_v5 ctcae5:C145753 Life-threatening consequences; hemodynamic or neurologic instability; organ damage; loss of extremity(ies) Life-threatening consequences; hemodynamic or neurologic instability; organ damage; loss of extremity(ies) Grade 4 Arterial Thromboembolism, CTCAE Grade 4 Arterial thromboembolism 10073529 C145753 Grade 4 Arterial thromboembolism Grade 4 Arterial thromboembolism Life-threatening consequences; hemodynamic or neurologic instability; organ damage; loss of extremity(ies) NCI Life-threatening consequences; hemodynamic or neurologic instability; organ damage; loss of extremity(ies) CTCAE_v5 Grade 4 Arterial Thromboembolism, CTCAE PT NCI Grade 4 Arterial thromboembolism PT CTCAE_v5 ctcae5:C145754 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Arteritis Infective, CTCAE Grade 4 Arteritis infective 10065744 C145754 Grade 4 Arteritis infective Grade 4 Arteritis infective Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Arteritis Infective, CTCAE PT NCI Grade 4 Arteritis infective PT CTCAE_v5 ctcae5:C145755 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ascites Grade 4 Ascites, CTCAE 10003445 C145755 Grade 4 Ascites Grade 4 Ascites Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ascites PT CTCAE_v5 Grade 4 Ascites, CTCAE PT NCI ctcae5:C145756 >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal Grade 4 Aspartate Aminotransferase Increased, CTCAE Grade 4 Aspartate aminotransferase increased 10003481 C145756 Grade 4 Aspartate aminotransferase increased Grade 4 Aspartate aminotransferase increased >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal NCI >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 4 Aspartate Aminotransferase Increased, CTCAE PT NCI Grade 4 Aspartate aminotransferase increased PT CTCAE_v5 ctcae5:C145757 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Atrioventricular Block Complete, CTCAE Grade 4 Atrioventricular block complete 10003673 C145757 Grade 4 Atrioventricular block complete Grade 4 Atrioventricular block complete Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Atrioventricular Block Complete, CTCAE PT NCI Grade 4 Atrioventricular block complete PT CTCAE_v5 ctcae5:C145758 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Autoimmune Disorder, CTCAE Grade 4 Autoimmune disorder 10061664 C145758 Grade 4 Autoimmune disorder Grade 4 Autoimmune disorder Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Autoimmune Disorder, CTCAE PT NCI Grade 4 Autoimmune disorder PT CTCAE_v5 ctcae5:C145759 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Avascular Necrosis, CTCAE Grade 4 Avascular necrosis 10066480 C145759 Grade 4 Avascular necrosis Grade 4 Avascular necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Avascular Necrosis, CTCAE PT NCI Grade 4 Avascular necrosis PT CTCAE_v5 ctcae5:C145760 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Bile Duct Stenosis, CTCAE Grade 4 Bile duct stenosis 10051341 C145760 Grade 4 Bile duct stenosis Grade 4 Bile duct stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Bile Duct Stenosis, CTCAE PT NCI Grade 4 Bile duct stenosis PT CTCAE_v5 ctcae5:C145761 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Biliary Anastomotic Leak, CTCAE Grade 4 Biliary anastomotic leak 10050458 C145761 Grade 4 Biliary anastomotic leak Grade 4 Biliary anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Biliary Anastomotic Leak, CTCAE PT NCI Grade 4 Biliary anastomotic leak PT CTCAE_v5 ctcae5:C145762 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Biliary Fistula, CTCAE Grade 4 Biliary fistula 10004665 C145762 Grade 4 Biliary fistula Grade 4 Biliary fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Biliary Fistula, CTCAE PT NCI Grade 4 Biliary fistula PT CTCAE_v5 ctcae5:C145763 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Biliary Tract Infection, CTCAE Grade 4 Biliary tract infection 10061695 C145763 Grade 4 Biliary tract infection Grade 4 Biliary tract infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Biliary Tract Infection, CTCAE PT NCI Grade 4 Biliary tract infection PT CTCAE_v5 ctcae5:C145764 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Bladder Anastomotic Leak, CTCAE Grade 4 Bladder anastomotic leak 10065802 C145764 Grade 4 Bladder anastomotic leak Grade 4 Bladder anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Bladder Anastomotic Leak, CTCAE PT NCI Grade 4 Bladder anastomotic leak PT CTCAE_v5 ctcae5:C145765 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Bladder Infection, CTCAE Grade 4 Bladder infection 10005047 C145765 Grade 4 Bladder infection Grade 4 Bladder infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Bladder Infection, CTCAE PT NCI Grade 4 Bladder infection PT CTCAE_v5 ctcae5:C145766 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Grade 4 Blood and lymphatic system disorders - Other, specify 10005329 C145766 Grade 4 Blood and lymphatic system disorders - Other, specify Grade 4 Blood and lymphatic system disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Grade 4 Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C145767 >10.0 x ULN if baseline was normal; >10.0 x baseline if baseline was abnormal >10.0 x ULN if baseline was normal; >10.0 x baseline if baseline was abnormal Grade 4 Blood Bilirubin Increased, CTCAE Grade 4 Blood bilirubin increased 10005364 C145767 Grade 4 Blood bilirubin increased Grade 4 Blood bilirubin increased >10.0 x ULN if baseline was normal; >10.0 x baseline if baseline was abnormal NCI >10.0 x ULN if baseline was normal; >10.0 x baseline if baseline was abnormal CTCAE_v5 Grade 4 Blood Bilirubin Increased, CTCAE PT NCI Grade 4 Blood bilirubin increased PT CTCAE_v5 ctcae5:C145768 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Bone Infection, CTCAE Grade 4 Bone infection 10061017 C145768 Grade 4 Bone infection Grade 4 Bone infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Bone Infection, CTCAE PT NCI Grade 4 Bone infection PT CTCAE_v5 ctcae5:C145769 Aplastic persistent for longer than 2 weeks Aplastic persistent for longer than 2 weeks Grade 4 Bone Marrow Hypocellular, CTCAE Grade 4 Bone marrow hypocellular 10048580 C145769 Grade 4 Bone marrow hypocellular Grade 4 Bone marrow hypocellular Aplastic persistent for longer than 2 weeks NCI Aplastic persistent for longer than 2 weeks CTCAE_v5 Grade 4 Bone Marrow Hypocellular, CTCAE PT NCI Grade 4 Bone marrow hypocellular PT CTCAE_v5 ctcae5:C145770 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Breast Infection, CTCAE Grade 4 Breast infection 10006259 C145770 Grade 4 Breast infection Grade 4 Breast infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Breast Infection, CTCAE PT NCI Grade 4 Breast infection PT CTCAE_v5 ctcae5:C145771 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Bronchial Fistula, CTCAE Grade 4 Bronchial fistula 10006437 C145771 Grade 4 Bronchial fistula Grade 4 Bronchial fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Bronchial Fistula, CTCAE PT NCI Grade 4 Bronchial fistula PT CTCAE_v5 ctcae5:C145772 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Bronchial Infection, CTCAE Grade 4 Bronchial infection 10055078 C145772 Grade 4 Bronchial infection Grade 4 Bronchial infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Bronchial Infection, CTCAE PT NCI Grade 4 Bronchial infection PT CTCAE_v5 ctcae5:C145773 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Bronchial Obstruction, CTCAE Grade 4 Bronchial obstruction 10006440 C145773 Grade 4 Bronchial obstruction Grade 4 Bronchial obstruction Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Bronchial Obstruction, CTCAE PT NCI Grade 4 Bronchial obstruction PT CTCAE_v5 ctcae5:C145774 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Bronchial Stricture, CTCAE Grade 4 Bronchial stricture 10063524 C145774 Grade 4 Bronchial stricture Grade 4 Bronchial stricture Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Bronchial Stricture, CTCAE PT NCI Grade 4 Bronchial stricture PT CTCAE_v5 ctcae5:C145775 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Bronchopleural Fistula, CTCAE Grade 4 Bronchopleural fistula 10053481 C145775 Grade 4 Bronchopleural fistula Grade 4 Bronchopleural fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Bronchopleural Fistula, CTCAE PT NCI Grade 4 Bronchopleural fistula PT CTCAE_v5 ctcae5:C145776 Life-threatening consequences; intubation or urgent intervention indicated Life-threatening consequences; intubation or urgent intervention indicated Grade 4 Bronchopulmonary Hemorrhage, CTCAE Grade 4 Bronchopulmonary hemorrhage 10065746 C145776 Grade 4 Bronchopulmonary hemorrhage Grade 4 Bronchopulmonary hemorrhage Life-threatening consequences; intubation or urgent intervention indicated NCI Life-threatening consequences; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Bronchopulmonary Hemorrhage, CTCAE PT NCI Grade 4 Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C145777 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Bronchospasm Grade 4 Bronchospasm, CTCAE 10006482 C145777 Grade 4 Bronchospasm Grade 4 Bronchospasm Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Bronchospasm PT CTCAE_v5 Grade 4 Bronchospasm, CTCAE PT NCI ctcae5:C145778 Life-threatening consequences; moderate to severe encephalopathy; coma Life-threatening consequences; moderate to severe encephalopathy; coma Grade 4 Budd-Chiari Syndrome, CTCAE Grade 4 Budd-Chiari syndrome 10006537 C145778 Grade 4 Budd-Chiari syndrome Grade 4 Budd-Chiari syndrome Life-threatening consequences; moderate to severe encephalopathy; coma NCI Life-threatening consequences; moderate to severe encephalopathy; coma CTCAE_v5 Grade 4 Budd-Chiari Syndrome, CTCAE PT NCI Grade 4 Budd-Chiari syndrome PT CTCAE_v5 ctcae5:C145779 Blisters covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated Blisters covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated Grade 4 Bullous Dermatitis, CTCAE Grade 4 Bullous dermatitis 10006556 C145779 Grade 4 Bullous dermatitis Grade 4 Bullous dermatitis Blisters covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated NCI Blisters covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated CTCAE_v5 Grade 4 Bullous Dermatitis, CTCAE PT NCI Grade 4 Bullous dermatitis PT CTCAE_v5 ctcae5:C145780 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Capillary Leak Syndrome, CTCAE Grade 4 Capillary leak syndrome 10007196 C145780 Grade 4 Capillary leak syndrome Grade 4 Capillary leak syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Capillary Leak Syndrome, CTCAE PT NCI Grade 4 Capillary leak syndrome PT CTCAE_v5 ctcae5:C145781 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cardiac Arrest, CTCAE Grade 4 Cardiac arrest 10007515 C145781 Grade 4 Cardiac arrest Grade 4 Cardiac arrest Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cardiac Arrest, CTCAE PT NCI Grade 4 Cardiac arrest PT CTCAE_v5 ctcae5:C145782 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cardiac Disorders - Other, Specify, CTCAE Grade 4 Cardiac disorders - Other, specify 10007541 C145782 Grade 4 Cardiac disorders - Other, specify Grade 4 Cardiac disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cardiac Disorders - Other, Specify, CTCAE PT NCI Grade 4 Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C145783 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Cataract Grade 4 Cataract, CTCAE 10007739 C145783 Grade 4 Cataract Grade 4 Cataract Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Cataract PT CTCAE_v5 Grade 4 Cataract, CTCAE PT NCI ctcae5:C145784 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Catheter Related Infection, CTCAE Grade 4 Catheter related infection 10007810 C145784 Grade 4 Catheter related infection Grade 4 Catheter related infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Catheter Related Infection, CTCAE PT NCI Grade 4 Catheter related infection PT CTCAE_v5 ctcae5:C145785 <50/mm3; <0.05 x 10e9/L <50/mm3; <0.05 x 10e9/L Grade 4 CD4 Lymphocytes Decreased, CTCAE Grade 4 CD4 lymphocytes decreased 10007839 C145785 Grade 4 CD4 lymphocytes decreased Grade 4 CD4 lymphocytes decreased <50/mm3; <0.05 x 10e9/L NCI <50/mm3; <0.05 x 10e9/L CTCAE_v5 Grade 4 CD4 Lymphocytes Decreased, CTCAE PT NCI Grade 4 CD4 lymphocytes decreased PT CTCAE_v5 ctcae5:C145786 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cecal Hemorrhage, CTCAE Grade 4 Cecal hemorrhage 10065747 C145786 Grade 4 Cecal hemorrhage Grade 4 Cecal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cecal Hemorrhage, CTCAE PT NCI Grade 4 Cecal hemorrhage PT CTCAE_v5 ctcae5:C145787 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cecal Infection, CTCAE Grade 4 Cecal infection 10065761 C145787 Grade 4 Cecal infection Grade 4 Cecal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cecal Infection, CTCAE PT NCI Grade 4 Cecal infection PT CTCAE_v5 ctcae5:C145788 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Central Nervous System Necrosis, CTCAE Grade 4 Central nervous system necrosis 10065784 C145788 Grade 4 Central nervous system necrosis Grade 4 Central nervous system necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Central Nervous System Necrosis, CTCAE PT NCI Grade 4 Central nervous system necrosis PT CTCAE_v5 ctcae5:C145789 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cerebrospinal Fluid Leakage, CTCAE Grade 4 Cerebrospinal fluid leakage 10008164 C145789 Grade 4 Cerebrospinal fluid leakage Grade 4 Cerebrospinal fluid leakage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cerebrospinal Fluid Leakage, CTCAE PT NCI Grade 4 Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C145790 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cervicitis Infection, CTCAE Grade 4 Cervicitis infection 10008330 C145790 Grade 4 Cervicitis infection Grade 4 Cervicitis infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cervicitis Infection, CTCAE PT NCI Grade 4 Cervicitis infection PT CTCAE_v5 ctcae5:C145791 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Chest Wall Necrosis, CTCAE Grade 4 Chest wall necrosis 10048831 C145791 Grade 4 Chest wall necrosis Grade 4 Chest wall necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Chest Wall Necrosis, CTCAE PT NCI Grade 4 Chest wall necrosis PT CTCAE_v5 ctcae5:C145792 >500 mg/dL; >12.92 mmol/L >500 mg/dL; >12.92 mmol/L Grade 4 Cholesterol High, CTCAE Grade 4 Cholesterol high 10008661 C145792 Grade 4 Cholesterol high Grade 4 Cholesterol high >500 mg/dL; >12.92 mmol/L NCI >500 mg/dL; >12.92 mmol/L CTCAE_v5 Grade 4 Cholesterol High, CTCAE PT NCI Grade 4 Cholesterol high PT CTCAE_v5 ctcae5:C145793 eGFR or CrCl <15 ml/min/1.73 m2; dialysis or renal transplant indicated eGFR or CrCl <15 ml/min/1.73 m2; dialysis or renal transplant indicated Grade 4 Chronic Kidney Disease, CTCAE Grade 4 Chronic kidney disease 10064848 C145793 Grade 4 Chronic kidney disease Grade 4 Chronic kidney disease eGFR or CrCl <15 ml/min/1.73 m2; dialysis or renal transplant indicated NCI eGFR or CrCl <15 ml/min/1.73 m2; dialysis or renal transplant indicated CTCAE_v5 Grade 4 Chronic Kidney Disease, CTCAE PT NCI Grade 4 Chronic kidney disease PT CTCAE_v5 ctcae5:C145794 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Chylous Ascites, CTCAE Grade 4 Chylous ascites 10009167 C145794 Grade 4 Chylous ascites Grade 4 Chylous ascites Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Chylous Ascites, CTCAE PT NCI Grade 4 Chylous ascites PT CTCAE_v5 ctcae5:C145795 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Colonic Fistula, CTCAE Grade 4 Colonic fistula 10009995 C145795 Grade 4 Colonic fistula Grade 4 Colonic fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Colonic Fistula, CTCAE PT NCI Grade 4 Colonic fistula PT CTCAE_v5 ctcae5:C145796 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Colonic Hemorrhage, CTCAE Grade 4 Colonic hemorrhage 10009998 C145796 Grade 4 Colonic hemorrhage Grade 4 Colonic hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Colonic Hemorrhage, CTCAE PT NCI Grade 4 Colonic hemorrhage PT CTCAE_v5 ctcae5:C145797 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Colonic Obstruction, CTCAE Grade 4 Colonic obstruction 10010000 C145797 Grade 4 Colonic obstruction Grade 4 Colonic obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Colonic Obstruction, CTCAE PT NCI Grade 4 Colonic obstruction PT CTCAE_v5 ctcae5:C145798 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Colonic Perforation, CTCAE Grade 4 Colonic perforation 10010001 C145798 Grade 4 Colonic perforation Grade 4 Colonic perforation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Colonic Perforation, CTCAE PT NCI Grade 4 Colonic perforation PT CTCAE_v5 ctcae5:C145799 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Colonic Stenosis, CTCAE Grade 4 Colonic stenosis 10010004 C145799 Grade 4 Colonic stenosis Grade 4 Colonic stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Colonic Stenosis, CTCAE PT NCI Grade 4 Colonic stenosis PT CTCAE_v5 ctcae5:C145800 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Colonic Ulcer, CTCAE Grade 4 Colonic ulcer 10010006 C145800 Grade 4 Colonic ulcer Grade 4 Colonic ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Colonic Ulcer, CTCAE PT NCI Grade 4 Colonic ulcer PT CTCAE_v5 ctcae5:C145801 Life-threatening consequences Life-threatening consequences Grade 4 Conduction Disorder, CTCAE Grade 4 Conduction disorder 10010276 C145801 Grade 4 Conduction disorder Grade 4 Conduction disorder Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Conduction Disorder, CTCAE PT NCI Grade 4 Conduction disorder PT CTCAE_v5 ctcae5:C145802 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Grade 4 Congenital, familial and genetic disorders - Other, specify 10010331 C145802 Grade 4 Congenital, familial and genetic disorders - Other, specify Grade 4 Congenital, familial and genetic disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Grade 4 Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C145803 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Conjunctivitis Infective, CTCAE Grade 4 Conjunctivitis infective 10010742 C145803 Grade 4 Conjunctivitis infective Grade 4 Conjunctivitis infective Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Conjunctivitis Infective, CTCAE PT NCI Grade 4 Conjunctivitis infective PT CTCAE_v5 ctcae5:C145804 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Conjunctivitis Grade 4 Conjunctivitis, CTCAE 10010741 C145804 Grade 4 Conjunctivitis Grade 4 Conjunctivitis Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Conjunctivitis PT CTCAE_v5 Grade 4 Conjunctivitis, CTCAE PT NCI ctcae5:C145805 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Corneal Infection, CTCAE Grade 4 Corneal infection 10061788 C145805 Grade 4 Corneal infection Grade 4 Corneal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Corneal Infection, CTCAE PT NCI Grade 4 Corneal infection PT CTCAE_v5 ctcae5:C145806 Perforation in the affected eye Perforation in the affected eye Grade 4 Corneal Ulcer, CTCAE Grade 4 Corneal ulcer 10048492 C145806 Grade 4 Corneal ulcer Grade 4 Corneal ulcer Perforation in the affected eye NCI Perforation in the affected eye CTCAE_v5 Grade 4 Corneal Ulcer, CTCAE PT NCI Grade 4 Corneal ulcer PT CTCAE_v5 ctcae5:C145807 >10 x ULN >10 x ULN Grade 4 CPK Increased, CTCAE Grade 4 CPK increased 10011268 C145807 Grade 4 CPK increased Grade 4 CPK increased >10 x ULN NCI >10 x ULN CTCAE_v5 Grade 4 CPK Increased, CTCAE PT NCI Grade 4 CPK increased PT CTCAE_v5 ctcae5:C145808 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cranial Nerve Infection, CTCAE Grade 4 Cranial nerve infection 10065765 C145808 Grade 4 Cranial nerve infection Grade 4 Cranial nerve infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cranial Nerve Infection, CTCAE PT NCI Grade 4 Cranial nerve infection PT CTCAE_v5 ctcae5:C145809 >6.0 x ULN >6.0 x ULN Grade 4 Creatinine Increased, CTCAE Grade 4 Creatinine increased 10011368 C145809 Grade 4 Creatinine increased Grade 4 Creatinine increased >6.0 x ULN NCI >6.0 x ULN CTCAE_v5 Grade 4 Creatinine Increased, CTCAE PT NCI Grade 4 Creatinine increased PT CTCAE_v5 ctcae5:C145810 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Cystitis Noninfective, CTCAE Grade 4 Cystitis noninfective 10063057 C145810 Grade 4 Cystitis noninfective Grade 4 Cystitis noninfective Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Cystitis Noninfective, CTCAE PT NCI Grade 4 Cystitis noninfective PT CTCAE_v5 ctcae5:C145811 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Cytokine Release Syndrome, CTCAE Grade 4 Cytokine release syndrome 10052015 C145811 Grade 4 Cytokine release syndrome Grade 4 Cytokine release syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Cytokine Release Syndrome, CTCAE PT NCI Grade 4 Cytokine release syndrome PT CTCAE_v5 ctcae5:C145812 Life-threatening consequences; urgent intervention indicated; blindness Life-threatening consequences; urgent intervention indicated; blindness Grade 4 Cytomegalovirus Infection Reactivation, CTCAE Grade 4 Cytomegalovirus infection reactivation 10058666 C145812 Grade 4 Cytomegalovirus infection reactivation Grade 4 Cytomegalovirus infection reactivation Life-threatening consequences; urgent intervention indicated; blindness NCI Life-threatening consequences; urgent intervention indicated; blindness CTCAE_v5 Grade 4 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Grade 4 Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C145813 Neonatal loss of life Neonatal loss of life Grade 4 Death Neonatal, CTCAE Grade 4 Death neonatal 10011912 C145813 Grade 4 Death neonatal Grade 4 Death neonatal Neonatal loss of life NCI Neonatal loss of life CTCAE_v5 Grade 4 Death Neonatal, CTCAE PT NCI Grade 4 Death neonatal PT CTCAE_v5 ctcae5:C145814 Life-threatening consequences, threats of harm to self or others; urgent intervention indicated Life-threatening consequences, threats of harm to self or others; urgent intervention indicated Grade 4 Delirium Grade 4 Delirium, CTCAE 10012218 C145814 Grade 4 Delirium Grade 4 Delirium Life-threatening consequences, threats of harm to self or others; urgent intervention indicated NCI Life-threatening consequences, threats of harm to self or others; urgent intervention indicated CTCAE_v5 Grade 4 Delirium PT CTCAE_v5 Grade 4 Delirium, CTCAE PT NCI ctcae5:C145815 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Delusions Grade 4 Delusions, CTCAE 10012260 C145815 Grade 4 Delusions Grade 4 Delusions Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Delusions PT CTCAE_v5 Grade 4 Delusions, CTCAE PT NCI ctcae5:C145816 Life-threatening consequences; coma; urgent intervention indicated Life-threatening consequences; coma; urgent intervention indicated Grade 4 Depressed Level of Consciousness, CTCAE Grade 4 Depressed level of consciousness 10012373 C145816 Grade 4 Depressed level of consciousness Grade 4 Depressed level of consciousness Life-threatening consequences; coma; urgent intervention indicated NCI Life-threatening consequences; coma; urgent intervention indicated CTCAE_v5 Grade 4 Depressed Level of Consciousness, CTCAE PT NCI Grade 4 Depressed level of consciousness PT CTCAE_v5 ctcae5:C145817 Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated Grade 4 Dermatitis Radiation, CTCAE Grade 4 Dermatitis radiation 10061103 C145817 Grade 4 Dermatitis radiation Grade 4 Dermatitis radiation Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated NCI Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated CTCAE_v5 Grade 4 Dermatitis Radiation, CTCAE PT NCI Grade 4 Dermatitis radiation PT CTCAE_v5 ctcae5:C145818 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Device Related Infection, CTCAE Grade 4 Device related infection 10064687 C145818 Grade 4 Device related infection Grade 4 Device related infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Device Related Infection, CTCAE PT NCI Grade 4 Device related infection PT CTCAE_v5 ctcae5:C145820 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Duodenal Hemorrhage, CTCAE Grade 4 Duodenal hemorrhage 10055242 C145820 Grade 4 Duodenal hemorrhage Grade 4 Duodenal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Duodenal Hemorrhage, CTCAE PT NCI Grade 4 Duodenal hemorrhage PT CTCAE_v5 ctcae5:C145821 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Duodenal Infection, CTCAE Grade 4 Duodenal infection 10065752 C145821 Grade 4 Duodenal infection Grade 4 Duodenal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Duodenal Infection, CTCAE PT NCI Grade 4 Duodenal infection PT CTCAE_v5 ctcae5:C145822 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Duodenal Obstruction, CTCAE Grade 4 Duodenal obstruction 10013830 C145822 Grade 4 Duodenal obstruction Grade 4 Duodenal obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Duodenal Obstruction, CTCAE PT NCI Grade 4 Duodenal obstruction PT CTCAE_v5 ctcae5:C145823 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Duodenal Perforation, CTCAE Grade 4 Duodenal perforation 10013832 C145823 Grade 4 Duodenal perforation Grade 4 Duodenal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Duodenal Perforation, CTCAE PT NCI Grade 4 Duodenal perforation PT CTCAE_v5 ctcae5:C145824 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Duodenal Stenosis, CTCAE Grade 4 Duodenal stenosis 10050094 C145824 Grade 4 Duodenal stenosis Grade 4 Duodenal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Duodenal Stenosis, CTCAE PT NCI Grade 4 Duodenal stenosis PT CTCAE_v5 ctcae5:C145825 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Duodenal Ulcer, CTCAE Grade 4 Duodenal ulcer 10013836 C145825 Grade 4 Duodenal ulcer Grade 4 Duodenal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Duodenal Ulcer, CTCAE PT NCI Grade 4 Duodenal ulcer PT CTCAE_v5 ctcae5:C145826 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ear and Labyrinth Disorders - Other, Specify, CTCAE Grade 4 Ear and labyrinth disorders - Other, specify 10013993 C145826 Grade 4 Ear and labyrinth disorders - Other, specify Grade 4 Ear and labyrinth disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Grade 4 Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C145827 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Edema Cerebral, CTCAE Grade 4 Edema cerebral 10014217 C145827 Grade 4 Edema cerebral Grade 4 Edema cerebral Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Edema Cerebral, CTCAE PT NCI Grade 4 Edema cerebral PT CTCAE_v5 ctcae5:C145828 Resting ejection fraction (EF) <20% Resting ejection fraction (EF) <20% Grade 4 Ejection Fraction Decreased, CTCAE Grade 4 Ejection fraction decreased 10050528 C145828 Grade 4 Ejection fraction decreased Grade 4 Ejection fraction decreased Resting ejection fraction (EF) <20% NCI Resting ejection fraction (EF) <20% CTCAE_v5 Grade 4 Ejection Fraction Decreased, CTCAE PT NCI Grade 4 Ejection fraction decreased PT CTCAE_v5 ctcae5:C145829 Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia Grade 4 Electrocardiogram QT Corrected Interval Prolonged, CTCAE Grade 4 Electrocardiogram QT corrected interval prolonged 10014383 C145829 Grade 4 Electrocardiogram QT corrected interval prolonged Grade 4 Electrocardiogram QT corrected interval prolonged Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia NCI Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia CTCAE_v5 Grade 4 Electrocardiogram QT Corrected Interval Prolonged, CTCAE PT NCI Grade 4 Electrocardiogram QT corrected interval prolonged PT CTCAE_v5 ctcae5:C145830 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Encephalitis Infection, CTCAE Grade 4 Encephalitis infection 10014594 C145830 Grade 4 Encephalitis infection Grade 4 Encephalitis infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Encephalitis Infection, CTCAE PT NCI Grade 4 Encephalitis infection PT CTCAE_v5 ctcae5:C145831 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Encephalomyelitis Infection, CTCAE Grade 4 Encephalomyelitis infection 10014621 C145831 Grade 4 Encephalomyelitis infection Grade 4 Encephalomyelitis infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Encephalomyelitis Infection, CTCAE PT NCI Grade 4 Encephalomyelitis infection PT CTCAE_v5 ctcae5:C145832 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Endocarditis Infective, CTCAE Grade 4 Endocarditis infective 10014678 C145832 Grade 4 Endocarditis infective Grade 4 Endocarditis infective Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Endocarditis Infective, CTCAE PT NCI Grade 4 Endocarditis infective PT CTCAE_v5 ctcae5:C145833 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Endocrine Disorders - Other, Specify, CTCAE Grade 4 Endocrine disorders - Other, specify 10014698 C145833 Grade 4 Endocrine disorders - Other, specify Grade 4 Endocrine disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Endocrine Disorders - Other, Specify, CTCAE PT NCI Grade 4 Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C145834 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Endophthalmitis Grade 4 Endophthalmitis, CTCAE 10014801 C145834 Grade 4 Endophthalmitis Grade 4 Endophthalmitis Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Endophthalmitis PT CTCAE_v5 Grade 4 Endophthalmitis, CTCAE PT NCI ctcae5:C145835 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Enterocolitis Infectious, CTCAE Grade 4 Enterocolitis infectious 10058838 C145835 Grade 4 Enterocolitis infectious Grade 4 Enterocolitis infectious Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Enterocolitis Infectious, CTCAE PT NCI Grade 4 Enterocolitis infectious PT CTCAE_v5 ctcae5:C145836 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Enterocolitis Grade 4 Enterocolitis, CTCAE 10014893 C145836 Grade 4 Enterocolitis Grade 4 Enterocolitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Enterocolitis PT CTCAE_v5 Grade 4 Enterocolitis, CTCAE PT NCI ctcae5:C145837 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Enterovesical Fistula, CTCAE Grade 4 Enterovesical fistula 10062570 C145837 Grade 4 Enterovesical fistula Grade 4 Enterovesical fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Enterovesical Fistula, CTCAE PT NCI Grade 4 Enterovesical fistula PT CTCAE_v5 ctcae5:C145838 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Epistaxis Grade 4 Epistaxis, CTCAE 10015090 C145838 Grade 4 Epistaxis Grade 4 Epistaxis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Epistaxis PT CTCAE_v5 Grade 4 Epistaxis, CTCAE PT NCI ctcae5:C145839 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Epstein-Barr Virus Infection Reactivation, CTCAE Grade 4 Epstein-Barr virus infection reactivation 10015109 C145839 Grade 4 Epstein-Barr virus infection reactivation Grade 4 Epstein-Barr virus infection reactivation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Grade 4 Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C145840 Target lesions covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated Target lesions covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated Grade 4 Erythema Multiforme, CTCAE Grade 4 Erythema multiforme 10015218 C145840 Grade 4 Erythema multiforme Grade 4 Erythema multiforme Target lesions covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated NCI Target lesions covering >30% BSA; associated with fluid or electrolyte abnormalities; ICU care or burn unit indicated CTCAE_v5 Grade 4 Erythema Multiforme, CTCAE PT NCI Grade 4 Erythema multiforme PT CTCAE_v5 ctcae5:C145841 Erythema covering >90% BSA with associated fluid or electrolyte abnormalities; ICU care or burn unit indicated Erythema covering >90% BSA with associated fluid or electrolyte abnormalities; ICU care or burn unit indicated Grade 4 Erythroderma Grade 4 Erythroderma, CTCAE 10015277 C145841 Grade 4 Erythroderma Grade 4 Erythroderma Erythema covering >90% BSA with associated fluid or electrolyte abnormalities; ICU care or burn unit indicated NCI Erythema covering >90% BSA with associated fluid or electrolyte abnormalities; ICU care or burn unit indicated CTCAE_v5 Grade 4 Erythroderma PT CTCAE_v5 Grade 4 Erythroderma, CTCAE PT NCI ctcae5:C145842 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophageal Anastomotic Leak, CTCAE Grade 4 Esophageal anastomotic leak 10065961 C145842 Grade 4 Esophageal anastomotic leak Grade 4 Esophageal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophageal Anastomotic Leak, CTCAE PT NCI Grade 4 Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C145844 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Esophageal Hemorrhage, CTCAE Grade 4 Esophageal hemorrhage 10015384 C145844 Grade 4 Esophageal hemorrhage Grade 4 Esophageal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Esophageal Hemorrhage, CTCAE PT NCI Grade 4 Esophageal hemorrhage PT CTCAE_v5 ctcae5:C145845 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Esophageal Infection, CTCAE Grade 4 Esophageal infection 10058804 C145845 Grade 4 Esophageal infection Grade 4 Esophageal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Esophageal Infection, CTCAE PT NCI Grade 4 Esophageal infection PT CTCAE_v5 ctcae5:C145846 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophageal Necrosis, CTCAE Grade 4 Esophageal necrosis 10065727 C145846 Grade 4 Esophageal necrosis Grade 4 Esophageal necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophageal Necrosis, CTCAE PT NCI Grade 4 Esophageal necrosis PT CTCAE_v5 ctcae5:C145847 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Esophageal Obstruction, CTCAE Grade 4 Esophageal obstruction 10015387 C145847 Grade 4 Esophageal obstruction Grade 4 Esophageal obstruction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Esophageal Obstruction, CTCAE PT NCI Grade 4 Esophageal obstruction PT CTCAE_v5 ctcae5:C145848 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophageal Perforation, CTCAE Grade 4 Esophageal perforation 10055472 C145848 Grade 4 Esophageal perforation Grade 4 Esophageal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophageal Perforation, CTCAE PT NCI Grade 4 Esophageal perforation PT CTCAE_v5 ctcae5:C145849 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophageal Stenosis, CTCAE Grade 4 Esophageal stenosis 10015448 C145849 Grade 4 Esophageal stenosis Grade 4 Esophageal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophageal Stenosis, CTCAE PT NCI Grade 4 Esophageal stenosis PT CTCAE_v5 ctcae5:C145850 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophageal Ulcer, CTCAE Grade 4 Esophageal ulcer 10015451 C145850 Grade 4 Esophageal ulcer Grade 4 Esophageal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophageal Ulcer, CTCAE PT NCI Grade 4 Esophageal ulcer PT CTCAE_v5 ctcae5:C145851 Bilateral paresis requiring head turning to see beyond central 60 degrees or double vision in central gaze Bilateral paresis requiring head turning to see beyond central 60 degrees or double vision in central gaze Grade 4 Extraocular Muscle Paresis, CTCAE Grade 4 Extraocular muscle paresis 10015829 C145851 Grade 4 Extraocular muscle paresis Grade 4 Extraocular muscle paresis Bilateral paresis requiring head turning to see beyond central 60 degrees or double vision in central gaze NCI Bilateral paresis requiring head turning to see beyond central 60 degrees or double vision in central gaze CTCAE_v5 Grade 4 Extraocular Muscle Paresis, CTCAE PT NCI Grade 4 Extraocular muscle paresis PT CTCAE_v5 ctcae5:C145852 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Extrapyramidal Disorder, CTCAE Grade 4 Extrapyramidal disorder 10015832 C145852 Grade 4 Extrapyramidal disorder Grade 4 Extrapyramidal disorder Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Extrapyramidal Disorder, CTCAE PT NCI Grade 4 Extrapyramidal disorder PT CTCAE_v5 ctcae5:C145853 Sight-threatening consequences; urgent intervention indicated; best corrected visual acuity of 20/200 or worse in the affected eye Sight-threatening consequences; urgent intervention indicated; best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Eye Disorders - Other, Specify, CTCAE Grade 4 Eye disorders - Other, specify 10015919 C145853 Grade 4 Eye disorders - Other, specify Grade 4 Eye disorders - Other, specify Sight-threatening consequences; urgent intervention indicated; best corrected visual acuity of 20/200 or worse in the affected eye NCI Sight-threatening consequences; urgent intervention indicated; best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Eye Disorders - Other, Specify, CTCAE PT NCI Grade 4 Eye disorders - Other, specify PT CTCAE_v5 ctcae5:C145854 Life-threatening consequences; urgent intervention indicated; enucleation Life-threatening consequences; urgent intervention indicated; enucleation Grade 4 Eye Infection, CTCAE Grade 4 Eye infection 10015929 C145854 Grade 4 Eye infection Grade 4 Eye infection Life-threatening consequences; urgent intervention indicated; enucleation NCI Life-threatening consequences; urgent intervention indicated; enucleation CTCAE_v5 Grade 4 Eye Infection, CTCAE PT NCI Grade 4 Eye infection PT CTCAE_v5 ctcae5:C145855 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Fallopian Tube Anastomotic Leak, CTCAE Grade 4 Fallopian tube anastomotic leak 10065788 C145855 Grade 4 Fallopian tube anastomotic leak Grade 4 Fallopian tube anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Grade 4 Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C145857 <1% percentile of weight for gestational age <1% percentile of weight for gestational age Grade 4 Fetal Growth Retardation, CTCAE Grade 4 Fetal growth retardation 10054746 C145857 Grade 4 Fetal growth retardation Grade 4 Fetal growth retardation <1% percentile of weight for gestational age NCI <1% percentile of weight for gestational age CTCAE_v5 Grade 4 Fetal Growth Retardation, CTCAE PT NCI Grade 4 Fetal growth retardation PT CTCAE_v5 ctcae5:C145858 >40.0 degrees C (>104.0 degrees F) for >24 hrs >40.0 degrees C (>104.0 degrees F) for >24 hrs Grade 4 Fever Grade 4 Fever, CTCAE 10016558 C145858 Grade 4 Fever Grade 4 Fever >40.0 degrees C (>104.0 degrees F) for >24 hrs NCI >40.0 degrees C (>104.0 degrees F) for >24 hrs CTCAE_v5 Grade 4 Fever PT CTCAE_v5 Grade 4 Fever, CTCAE PT NCI ctcae5:C145859 <0.25 x LLN; if abnormal, 75% decrease from baseline; absolute value <50 mg/dL <0.25 x LLN; if abnormal, 75% decrease from baseline; absolute value <50 mg/dL Grade 4 Fibrinogen Decreased, CTCAE Grade 4 Fibrinogen decreased 10016596 C145859 Grade 4 Fibrinogen decreased Grade 4 Fibrinogen decreased <0.25 x LLN; if abnormal, 75% decrease from baseline; absolute value <50 mg/dL NCI <0.25 x LLN; if abnormal, 75% decrease from baseline; absolute value <50 mg/dL CTCAE_v5 Grade 4 Fibrinogen Decreased, CTCAE PT NCI Grade 4 Fibrinogen decreased PT CTCAE_v5 ctcae5:C145860 Generalized; associated with signs or symptoms of impaired breathing or feeding Generalized; associated with signs or symptoms of impaired breathing or feeding Grade 4 Fibrosis Deep Connective Tissue, CTCAE Grade 4 Fibrosis deep connective tissue 10065799 C145860 Grade 4 Fibrosis deep connective tissue Grade 4 Fibrosis deep connective tissue Generalized; associated with signs or symptoms of impaired breathing or feeding NCI Generalized; associated with signs or symptoms of impaired breathing or feeding CTCAE_v5 Grade 4 Fibrosis Deep Connective Tissue, CTCAE PT NCI Grade 4 Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C145861 <=49% <=49% Grade 4 Forced Expiratory Volume Decreased, CTCAE Grade 4 Forced expiratory volume decreased 10016987 C145861 Grade 4 Forced expiratory volume decreased Grade 4 Forced expiratory volume decreased <=49% NCI <=49% CTCAE_v5 Grade 4 Forced Expiratory Volume Decreased, CTCAE PT NCI Grade 4 Forced expiratory volume decreased PT CTCAE_v5 ctcae5:C145862 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gallbladder Infection, CTCAE Grade 4 Gallbladder infection 10062632 C145862 Grade 4 Gallbladder infection Grade 4 Gallbladder infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gallbladder Infection, CTCAE PT NCI Grade 4 Gallbladder infection PT CTCAE_v5 ctcae5:C145863 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastric Anastomotic Leak, CTCAE Grade 4 Gastric anastomotic leak 10065893 C145863 Grade 4 Gastric anastomotic leak Grade 4 Gastric anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastric Anastomotic Leak, CTCAE PT NCI Grade 4 Gastric anastomotic leak PT CTCAE_v5 ctcae5:C145864 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastric Fistula, CTCAE Grade 4 Gastric fistula 10065713 C145864 Grade 4 Gastric fistula Grade 4 Gastric fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastric Fistula, CTCAE PT NCI Grade 4 Gastric fistula PT CTCAE_v5 ctcae5:C145865 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastric Hemorrhage, CTCAE Grade 4 Gastric hemorrhage 10017789 C145865 Grade 4 Gastric hemorrhage Grade 4 Gastric hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastric Hemorrhage, CTCAE PT NCI Grade 4 Gastric hemorrhage PT CTCAE_v5 ctcae5:C145866 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastric Necrosis, CTCAE Grade 4 Gastric necrosis 10051886 C145866 Grade 4 Gastric necrosis Grade 4 Gastric necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastric Necrosis, CTCAE PT NCI Grade 4 Gastric necrosis PT CTCAE_v5 ctcae5:C145867 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastric Perforation, CTCAE Grade 4 Gastric perforation 10017815 C145867 Grade 4 Gastric perforation Grade 4 Gastric perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastric Perforation, CTCAE PT NCI Grade 4 Gastric perforation PT CTCAE_v5 ctcae5:C145868 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastric Stenosis, CTCAE Grade 4 Gastric stenosis 10061970 C145868 Grade 4 Gastric stenosis Grade 4 Gastric stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastric Stenosis, CTCAE PT NCI Grade 4 Gastric stenosis PT CTCAE_v5 ctcae5:C145869 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastric Ulcer, CTCAE Grade 4 Gastric ulcer 10017822 C145869 Grade 4 Gastric ulcer Grade 4 Gastric ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastric Ulcer, CTCAE PT NCI Grade 4 Gastric ulcer PT CTCAE_v5 ctcae5:C145870 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastrointestinal Anastomotic Leak, CTCAE Grade 4 Gastrointestinal anastomotic leak 10065879 C145870 Grade 4 Gastrointestinal anastomotic leak Grade 4 Gastrointestinal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Grade 4 Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C145871 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastrointestinal Disorders - Other, Specify, CTCAE Grade 4 Gastrointestinal disorders - Other, specify 10017947 C145871 Grade 4 Gastrointestinal disorders - Other, specify Grade 4 Gastrointestinal disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Grade 4 Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C145872 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastrointestinal Fistula, CTCAE Grade 4 Gastrointestinal fistula 10017877 C145872 Grade 4 Gastrointestinal fistula Grade 4 Gastrointestinal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastrointestinal Fistula, CTCAE PT NCI Grade 4 Gastrointestinal fistula PT CTCAE_v5 ctcae5:C145873 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastrointestinal Stoma Necrosis, CTCAE Grade 4 Gastrointestinal stoma necrosis 10065712 C145873 Grade 4 Gastrointestinal stoma necrosis Grade 4 Gastrointestinal stoma necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastrointestinal Stoma Necrosis, CTCAE PT NCI Grade 4 Gastrointestinal stoma necrosis PT CTCAE_v5 ctcae5:C145874 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gastroparesis Grade 4 Gastroparesis, CTCAE 10018043 C145874 Grade 4 Gastroparesis Grade 4 Gastroparesis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gastroparesis PT CTCAE_v5 Grade 4 Gastroparesis, CTCAE PT NCI ctcae5:C145875 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 General Disorders and Administration Site Conditions - Other, Specify, CTCAE Grade 4 General disorders and administration site conditions - Other, specify 10018065 C145875 Grade 4 General disorders and administration site conditions - Other, specify Grade 4 General disorders and administration site conditions - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI Grade 4 General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C145876 Life-threatening consequences Life-threatening consequences Grade 4 Generalized Edema, CTCAE Grade 4 Generalized edema 10018112 C145876 Grade 4 Generalized edema Grade 4 Generalized edema Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Generalized Edema, CTCAE PT NCI Grade 4 Generalized edema PT CTCAE_v5 ctcae5:C145877 >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal Grade 4 GGT Increased, CTCAE Grade 4 GGT increased 10056910 C145877 Grade 4 GGT increased Grade 4 GGT increased >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal NCI >20.0 x ULN if baseline was normal; >20.0 x baseline if baseline was abnormal CTCAE_v5 Grade 4 GGT Increased, CTCAE PT NCI Grade 4 GGT increased PT CTCAE_v5 ctcae5:C145878 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Glossopharyngeal Nerve Disorder, CTCAE Grade 4 Glossopharyngeal nerve disorder 10061185 C145878 Grade 4 Glossopharyngeal nerve disorder Grade 4 Glossopharyngeal nerve disorder Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Grade 4 Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C145879 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Glucose Intolerance, CTCAE Grade 4 Glucose intolerance 10052426 C145879 Grade 4 Glucose intolerance Grade 4 Glucose intolerance Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Glucose Intolerance, CTCAE PT NCI Grade 4 Glucose intolerance PT CTCAE_v5 ctcae5:C145880 Life-threatening consequences; urgent intervention indicated; intubation Life-threatening consequences; urgent intervention indicated; intubation Grade 4 Guillain-Barre Syndrome, CTCAE Grade 4 Guillain-Barre syndrome 10018767 C145880 Grade 4 Guillain-Barre syndrome Grade 4 Guillain-Barre syndrome Life-threatening consequences; urgent intervention indicated; intubation NCI Life-threatening consequences; urgent intervention indicated; intubation CTCAE_v5 Grade 4 Guillain-Barre Syndrome, CTCAE PT NCI Grade 4 Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C145881 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gum Infection, CTCAE Grade 4 Gum infection 10018784 C145881 Grade 4 Gum infection Grade 4 Gum infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gum Infection, CTCAE PT NCI Grade 4 Gum infection PT CTCAE_v5 ctcae5:C145882 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Hallucinations Grade 4 Hallucinations, CTCAE 10019077 C145882 Grade 4 Hallucinations Grade 4 Hallucinations Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Hallucinations PT CTCAE_v5 Grade 4 Hallucinations, CTCAE PT NCI ctcae5:C145883 Adults: Decrease in hearing to profound bilateral loss (absolute threshold >80 dB HL at 2 kHz and above); nonservicable hearingPediatric: Audiologic indication for cochlear implant; > 40 dB HL (i.e., 45 dB HL or more); SNHL at 2 kHz and above Adults: Decrease in hearing to profound bilateral loss (absolute threshold >80 dB HL at 2 kHz and above); nonservicable hearingPediatric: Audiologic indication for cochlear implant; > 40 dB HL (i.e., 45 dB HL or more); SNHL at 2 kHz and above Grade 4 Hearing Impaired, CTCAE Grade 4 Hearing impaired 10019245 C145883 Grade 4 Hearing impaired Grade 4 Hearing impaired Adults: Decrease in hearing to profound bilateral loss (absolute threshold >80 dB HL at 2 kHz and above); nonservicable hearingPediatric: Audiologic indication for cochlear implant; > 40 dB HL (i.e., 45 dB HL or more); SNHL at 2 kHz and above NCI Adults: Decrease in hearing to profound bilateral loss (absolute threshold >80 dB HL at 2 kHz and above); nonservicable hearingPediatric: Audiologic indication for cochlear implant; > 40 dB HL (i.e., 45 dB HL or more); SNHL at 2 kHz and above CTCAE_v5 Grade 4 Hearing Impaired, CTCAE PT NCI Grade 4 Hearing impaired PT CTCAE_v5 ctcae5:C145884 Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) Grade 4 Heart Failure, CTCAE Grade 4 Heart failure 10019279 C145884 Grade 4 Heart failure Grade 4 Heart failure Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) NCI Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) CTCAE_v5 Grade 4 Heart Failure, CTCAE PT NCI Grade 4 Heart failure PT CTCAE_v5 ctcae5:C145885 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Hematosalpinx Grade 4 Hematosalpinx, CTCAE 10060602 C145885 Grade 4 Hematosalpinx Grade 4 Hematosalpinx Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Hematosalpinx PT CTCAE_v5 Grade 4 Hematosalpinx, CTCAE PT NCI ctcae5:C145886 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Hematuria Grade 4 Hematuria, CTCAE 10019450 C145886 Grade 4 Hematuria Grade 4 Hematuria Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Hematuria PT CTCAE_v5 Grade 4 Hematuria, CTCAE PT NCI ctcae5:C145887 Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) Grade 4 Hemolytic Uremic Syndrome, CTCAE Grade 4 Hemolytic uremic syndrome 10019515 C145887 Grade 4 Hemolytic uremic syndrome Grade 4 Hemolytic uremic syndrome Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) NCI Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) CTCAE_v5 Grade 4 Hemolytic Uremic Syndrome, CTCAE PT NCI Grade 4 Hemolytic uremic syndrome PT CTCAE_v5 ctcae5:C145888 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hemorrhoidal Hemorrhage, CTCAE Grade 4 Hemorrhoidal hemorrhage 10060640 C145888 Grade 4 Hemorrhoidal hemorrhage Grade 4 Hemorrhoidal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hemorrhoidal Hemorrhage, CTCAE PT NCI Grade 4 Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C145889 Life-threatening consequences; moderate to severe encephalopathy; coma Life-threatening consequences; moderate to severe encephalopathy; coma Grade 4 Hepatic Failure, CTCAE Grade 4 Hepatic failure 10019663 C145889 Grade 4 Hepatic failure Grade 4 Hepatic failure Life-threatening consequences; moderate to severe encephalopathy; coma NCI Life-threatening consequences; moderate to severe encephalopathy; coma CTCAE_v5 Grade 4 Hepatic Failure, CTCAE PT NCI Grade 4 Hepatic failure PT CTCAE_v5 ctcae5:C145890 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hepatic Hemorrhage, CTCAE Grade 4 Hepatic hemorrhage 10019678 C145890 Grade 4 Hepatic hemorrhage Grade 4 Hepatic hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hepatic Hemorrhage, CTCAE PT NCI Grade 4 Hepatic hemorrhage PT CTCAE_v5 ctcae5:C145891 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hepatic Infection, CTCAE Grade 4 Hepatic infection 10056522 C145891 Grade 4 Hepatic infection Grade 4 Hepatic infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hepatic Infection, CTCAE PT NCI Grade 4 Hepatic infection PT CTCAE_v5 ctcae5:C145892 Life-threatening consequences; urgent intervention indicated; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) Life-threatening consequences; urgent intervention indicated; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) Grade 4 Hepatitis B Reactivation, CTCAE Grade 4 Hepatitis B reactivation 10058827 C145892 Grade 4 Hepatitis B reactivation Grade 4 Hepatitis B reactivation Life-threatening consequences; urgent intervention indicated; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) NCI Life-threatening consequences; urgent intervention indicated; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) CTCAE_v5 Grade 4 Hepatitis B Reactivation, CTCAE PT NCI Grade 4 Hepatitis B reactivation PT CTCAE_v5 ctcae5:C145893 Life-threatening consequences; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) Life-threatening consequences; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) Grade 4 Hepatitis Viral, CTCAE Grade 4 Hepatitis viral 10019799 C145893 Grade 4 Hepatitis viral Grade 4 Hepatitis viral Life-threatening consequences; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) NCI Life-threatening consequences; severe decompensated liver function (e.g., coagulopathy, encephalopathy, coma) CTCAE_v5 Grade 4 Hepatitis Viral, CTCAE PT NCI Grade 4 Hepatitis viral PT CTCAE_v5 ctcae5:C145894 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hepatobiliary Disorders - Other, Specify, CTCAE Grade 4 Hepatobiliary disorders - Other, specify 10019805 C145894 Grade 4 Hepatobiliary disorders - Other, specify Grade 4 Hepatobiliary disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Grade 4 Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C145895 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Herpes Simplex Reactivation, CTCAE Grade 4 Herpes simplex reactivation 10080137 C145895 Grade 4 Herpes simplex reactivation Grade 4 Herpes simplex reactivation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Herpes Simplex Reactivation, CTCAE PT NCI Grade 4 Herpes simplex reactivation PT CTCAE_v5 ctcae5:C145896 Life-threatening consequences; symptoms associated with neurovascular compromise Life-threatening consequences; symptoms associated with neurovascular compromise Grade 4 Hip Fracture, CTCAE Grade 4 Hip fracture 10020100 C145896 Grade 4 Hip fracture Grade 4 Hip fracture Life-threatening consequences; symptoms associated with neurovascular compromise NCI Life-threatening consequences; symptoms associated with neurovascular compromise CTCAE_v5 Grade 4 Hip Fracture, CTCAE PT NCI Grade 4 Hip fracture PT CTCAE_v5 ctcae5:C145897 Corrected serum calcium of >13.5 mg/dL; >3.4 mmol/L; Ionized calcium >1.8 mmol/L; life-threatening consequences Corrected serum calcium of >13.5 mg/dL; >3.4 mmol/L; Ionized calcium >1.8 mmol/L; life-threatening consequences Grade 4 Hypercalcemia Grade 4 Hypercalcemia, CTCAE 10020587 C145897 Grade 4 Hypercalcemia Grade 4 Hypercalcemia Corrected serum calcium of >13.5 mg/dL; >3.4 mmol/L; Ionized calcium >1.8 mmol/L; life-threatening consequences NCI Corrected serum calcium of >13.5 mg/dL; >3.4 mmol/L; Ionized calcium >1.8 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypercalcemia PT CTCAE_v5 Grade 4 Hypercalcemia, CTCAE PT NCI ctcae5:C145898 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hyperglycemia Grade 4 Hyperglycemia, CTCAE 10020639 C145898 Grade 4 Hyperglycemia Grade 4 Hyperglycemia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hyperglycemia PT CTCAE_v5 Grade 4 Hyperglycemia, CTCAE PT NCI ctcae5:C145899 >7.0 mmol/L; life-threatening consequences >7.0 mmol/L; life-threatening consequences Grade 4 Hyperkalemia Grade 4 Hyperkalemia, CTCAE 10020647 C145899 Grade 4 Hyperkalemia Grade 4 Hyperkalemia >7.0 mmol/L; life-threatening consequences NCI >7.0 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hyperkalemia PT CTCAE_v5 Grade 4 Hyperkalemia, CTCAE PT NCI ctcae5:C145900 Life-threatening consequences Life-threatening consequences Grade 4 Hyperlipidemia Grade 4 Hyperlipidemia, CTCAE 10020667 C145900 Grade 4 Hyperlipidemia Grade 4 Hyperlipidemia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Hyperlipidemia PT CTCAE_v5 Grade 4 Hyperlipidemia, CTCAE PT NCI ctcae5:C145901 >8.0 mg/dL; >3.30 mmol/L; life-threatening consequences >8.0 mg/dL; >3.30 mmol/L; life-threatening consequences Grade 4 Hypermagnesemia Grade 4 Hypermagnesemia, CTCAE 10020670 C145901 Grade 4 Hypermagnesemia Grade 4 Hypermagnesemia >8.0 mg/dL; >3.30 mmol/L; life-threatening consequences NCI >8.0 mg/dL; >3.30 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypermagnesemia PT CTCAE_v5 Grade 4 Hypermagnesemia, CTCAE PT NCI ctcae5:C145902 >160 mmol/L; life-threatening consequences >160 mmol/L; life-threatening consequences Grade 4 Hypernatremia Grade 4 Hypernatremia, CTCAE 10020680 C145902 Grade 4 Hypernatremia Grade 4 Hypernatremia >160 mmol/L; life-threatening consequences NCI >160 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypernatremia PT CTCAE_v5 Grade 4 Hypernatremia, CTCAE PT NCI ctcae5:C145903 Life-threatening consequences; urgent intervention indicated (e.g., dialysis) Life-threatening consequences; urgent intervention indicated (e.g., dialysis) Grade 4 Hyperphosphatemia Grade 4 Hyperphosphatemia, CTCAE 10020712 C145903 Grade 4 Hyperphosphatemia Grade 4 Hyperphosphatemia Life-threatening consequences; urgent intervention indicated (e.g., dialysis) NCI Life-threatening consequences; urgent intervention indicated (e.g., dialysis) CTCAE_v5 Grade 4 Hyperphosphatemia PT CTCAE_v5 Grade 4 Hyperphosphatemia, CTCAE PT NCI ctcae5:C145904 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hyperthyroidism Grade 4 Hyperthyroidism, CTCAE 10020850 C145904 Grade 4 Hyperthyroidism Grade 4 Hyperthyroidism Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hyperthyroidism PT CTCAE_v5 Grade 4 Hyperthyroidism, CTCAE PT NCI ctcae5:C145905 >1000 mg/dL; >11.4 mmol/L; life-threatening consequences >1000 mg/dL; >11.4 mmol/L; life-threatening consequences Grade 4 Hypertriglyceridemia Grade 4 Hypertriglyceridemia, CTCAE 10020870 C145905 Grade 4 Hypertriglyceridemia Grade 4 Hypertriglyceridemia >1000 mg/dL; >11.4 mmol/L; life-threatening consequences NCI >1000 mg/dL; >11.4 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypertriglyceridemia PT CTCAE_v5 Grade 4 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C145906 Life-threatening consequences Life-threatening consequences Grade 4 Hyperuricemia Grade 4 Hyperuricemia, CTCAE 10020907 C145906 Grade 4 Hyperuricemia Grade 4 Hyperuricemia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Hyperuricemia PT CTCAE_v5 Grade 4 Hyperuricemia, CTCAE PT NCI ctcae5:C145907 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hypoalbuminemia Grade 4 Hypoalbuminemia, CTCAE 10020943 C145907 Grade 4 Hypoalbuminemia Grade 4 Hypoalbuminemia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hypoalbuminemia PT CTCAE_v5 Grade 4 Hypoalbuminemia, CTCAE PT NCI ctcae5:C145908 Corrected serum calcium of <6.0 mg/dL; <1.5 mmol/L; Ionized calcium <0.8 mmol/L; life-threatening consequences Corrected serum calcium of <6.0 mg/dL; <1.5 mmol/L; Ionized calcium <0.8 mmol/L; life-threatening consequences Grade 4 Hypocalcemia Grade 4 Hypocalcemia, CTCAE 10020949 C145908 Grade 4 Hypocalcemia Grade 4 Hypocalcemia Corrected serum calcium of <6.0 mg/dL; <1.5 mmol/L; Ionized calcium <0.8 mmol/L; life-threatening consequences NCI Corrected serum calcium of <6.0 mg/dL; <1.5 mmol/L; Ionized calcium <0.8 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypocalcemia PT CTCAE_v5 Grade 4 Hypocalcemia, CTCAE PT NCI ctcae5:C145909 <30 mg/dL; <1.7 mmol/L; life-threatening consequences; seizures <30 mg/dL; <1.7 mmol/L; life-threatening consequences; seizures Grade 4 Hypoglycemia Grade 4 Hypoglycemia, CTCAE 10021005 C145909 Grade 4 Hypoglycemia Grade 4 Hypoglycemia <30 mg/dL; <1.7 mmol/L; life-threatening consequences; seizures NCI <30 mg/dL; <1.7 mmol/L; life-threatening consequences; seizures CTCAE_v5 Grade 4 Hypoglycemia PT CTCAE_v5 Grade 4 Hypoglycemia, CTCAE PT NCI ctcae5:C145910 Heat stroke Heat stroke Grade 4 Hypohidrosis Grade 4 Hypohidrosis, CTCAE 10021013 C145910 Grade 4 Hypohidrosis Grade 4 Hypohidrosis Heat stroke NCI Heat stroke CTCAE_v5 Grade 4 Hypohidrosis PT CTCAE_v5 Grade 4 Hypohidrosis, CTCAE PT NCI ctcae5:C145911 <2.5 mmol/L; life-threatening consequences <2.5 mmol/L; life-threatening consequences Grade 4 Hypokalemia Grade 4 Hypokalemia, CTCAE 10021018 C145911 Grade 4 Hypokalemia Grade 4 Hypokalemia <2.5 mmol/L; life-threatening consequences NCI <2.5 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypokalemia PT CTCAE_v5 Grade 4 Hypokalemia, CTCAE PT NCI ctcae5:C145912 <0.7 mg/dL; <0.3 mmol/L; life-threatening consequences <0.7 mg/dL; <0.3 mmol/L; life-threatening consequences Grade 4 Hypomagnesemia Grade 4 Hypomagnesemia, CTCAE 10021028 C145912 Grade 4 Hypomagnesemia Grade 4 Hypomagnesemia <0.7 mg/dL; <0.3 mmol/L; life-threatening consequences NCI <0.7 mg/dL; <0.3 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hypomagnesemia PT CTCAE_v5 Grade 4 Hypomagnesemia, CTCAE PT NCI ctcae5:C145913 <120 mmol/L; life-threatening consequences <120 mmol/L; life-threatening consequences Grade 4 Hyponatremia Grade 4 Hyponatremia, CTCAE 10021038 C145913 Grade 4 Hyponatremia Grade 4 Hyponatremia <120 mmol/L; life-threatening consequences NCI <120 mmol/L; life-threatening consequences CTCAE_v5 Grade 4 Hyponatremia PT CTCAE_v5 Grade 4 Hyponatremia, CTCAE PT NCI ctcae5:C145914 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hypoparathyroidism Grade 4 Hypoparathyroidism, CTCAE 10021041 C145914 Grade 4 Hypoparathyroidism Grade 4 Hypoparathyroidism Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hypoparathyroidism PT CTCAE_v5 Grade 4 Hypoparathyroidism, CTCAE PT NCI ctcae5:C145915 Life-threatening consequences Life-threatening consequences Grade 4 Hypophosphatemia Grade 4 Hypophosphatemia, CTCAE 10021059 C145915 Grade 4 Hypophosphatemia Grade 4 Hypophosphatemia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Hypophosphatemia PT CTCAE_v5 Grade 4 Hypophosphatemia, CTCAE PT NCI ctcae5:C145916 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hypophysitis Grade 4 Hypophysitis, CTCAE 10062767 C145916 Grade 4 Hypophysitis Grade 4 Hypophysitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hypophysitis PT CTCAE_v5 Grade 4 Hypophysitis, CTCAE PT NCI ctcae5:C145917 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hypopituitarism Grade 4 Hypopituitarism, CTCAE 10021067 C145917 Grade 4 Hypopituitarism Grade 4 Hypopituitarism Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hypopituitarism PT CTCAE_v5 Grade 4 Hypopituitarism, CTCAE PT NCI ctcae5:C145918 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hypothyroidism Grade 4 Hypothyroidism, CTCAE 10021114 C145918 Grade 4 Hypothyroidism Grade 4 Hypothyroidism Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hypothyroidism PT CTCAE_v5 Grade 4 Hypothyroidism, CTCAE PT NCI ctcae5:C145922 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ileal Perforation, CTCAE Grade 4 Ileal perforation 10021305 C145922 Grade 4 Ileal perforation Grade 4 Ileal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ileal Perforation, CTCAE PT NCI Grade 4 Ileal perforation PT CTCAE_v5 ctcae5:C145923 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ileal Stenosis, CTCAE Grade 4 Ileal stenosis 10021307 C145923 Grade 4 Ileal stenosis Grade 4 Ileal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ileal Stenosis, CTCAE PT NCI Grade 4 Ileal stenosis PT CTCAE_v5 ctcae5:C145926 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Immune System Disorders - Other, Specify, CTCAE Grade 4 Immune system disorders - Other, specify 10021428 C145926 Grade 4 Immune system disorders - Other, specify Grade 4 Immune system disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Immune System Disorders - Other, Specify, CTCAE PT NCI Grade 4 Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C145927 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Infections and Infestations - Other, Specify, CTCAE Grade 4 Infections and infestations - Other, specify 10021881 C145927 Grade 4 Infections and infestations - Other, specify Grade 4 Infections and infestations - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Infections and Infestations - Other, Specify, CTCAE PT NCI Grade 4 Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C145928 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Infective Myositis, CTCAE Grade 4 Infective myositis 10021918 C145928 Grade 4 Infective myositis Grade 4 Infective myositis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Infective Myositis, CTCAE PT NCI Grade 4 Infective myositis PT CTCAE_v5 ctcae5:C145929 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Infusion Related Reaction, CTCAE Grade 4 Infusion related reaction 10051792 C145929 Grade 4 Infusion related reaction Grade 4 Infusion related reaction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Infusion Related Reaction, CTCAE PT NCI Grade 4 Infusion related reaction PT CTCAE_v5 ctcae5:C145930 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Infusion Site Extravasation, CTCAE Grade 4 Infusion site extravasation 10064774 C145930 Grade 4 Infusion site extravasation Grade 4 Infusion site extravasation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Infusion Site Extravasation, CTCAE PT NCI Grade 4 Infusion site extravasation PT CTCAE_v5 ctcae5:C145931 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injection Site Reaction, CTCAE Grade 4 Injection site reaction 10022095 C145931 Grade 4 Injection site reaction Grade 4 Injection site reaction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injection Site Reaction, CTCAE PT NCI Grade 4 Injection site reaction PT CTCAE_v5 ctcae5:C145932 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injury To Carotid Artery, CTCAE Grade 4 Injury to carotid artery 10022161 C145932 Grade 4 Injury to carotid artery Grade 4 Injury to carotid artery Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injury To Carotid Artery, CTCAE PT NCI Grade 4 Injury to carotid artery PT CTCAE_v5 ctcae5:C145934 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injury To Jugular Vein, CTCAE Grade 4 Injury to jugular vein 10065849 C145934 Grade 4 Injury to jugular vein Grade 4 Injury to jugular vein Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injury To Jugular Vein, CTCAE PT NCI Grade 4 Injury to jugular vein PT CTCAE_v5 ctcae5:C145935 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injury To Superior Vena Cava, CTCAE Grade 4 Injury to superior vena cava 10022356 C145935 Grade 4 Injury to superior vena cava Grade 4 Injury to superior vena cava Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injury To Superior Vena Cava, CTCAE PT NCI Grade 4 Injury to superior vena cava PT CTCAE_v5 ctcae5:C145936 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Grade 4 Injury, poisoning and procedural complications - Other, specify 10022117 C145936 Grade 4 Injury, poisoning and procedural complications - Other, specify Grade 4 Injury, poisoning and procedural complications - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Grade 4 Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C145937 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Intestinal Stoma Leak, CTCAE Grade 4 Intestinal stoma leak 10059095 C145937 Grade 4 Intestinal stoma leak Grade 4 Intestinal stoma leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Intestinal Stoma Leak, CTCAE PT NCI Grade 4 Intestinal stoma leak PT CTCAE_v5 ctcae5:C145938 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Intestinal Stoma Obstruction, CTCAE Grade 4 Intestinal stoma obstruction 10059094 C145938 Grade 4 Intestinal stoma obstruction Grade 4 Intestinal stoma obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Intestinal Stoma Obstruction, CTCAE PT NCI Grade 4 Intestinal stoma obstruction PT CTCAE_v5 ctcae5:C145939 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intestinal Stoma Site Bleeding, CTCAE Grade 4 Intestinal stoma site bleeding 10049468 C145939 Grade 4 Intestinal stoma site bleeding Grade 4 Intestinal stoma site bleeding Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intestinal Stoma Site Bleeding, CTCAE PT NCI Grade 4 Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C145940 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intra-Abdominal Hemorrhage, CTCAE Grade 4 Intra-abdominal hemorrhage 10055291 C145940 Grade 4 Intra-abdominal hemorrhage Grade 4 Intra-abdominal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intra-Abdominal Hemorrhage, CTCAE PT NCI Grade 4 Intra-abdominal hemorrhage PT CTCAE_v5 ctcae5:C145941 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intracranial Hemorrhage, CTCAE Grade 4 Intracranial hemorrhage 10022763 C145941 Grade 4 Intracranial hemorrhage Grade 4 Intracranial hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intracranial Hemorrhage, CTCAE PT NCI Grade 4 Intracranial hemorrhage PT CTCAE_v5 ctcae5:C145942 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Arterial Injury, CTCAE Grade 4 Intraoperative arterial injury 10065826 C145942 Grade 4 Intraoperative arterial injury Grade 4 Intraoperative arterial injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Arterial Injury, CTCAE PT NCI Grade 4 Intraoperative arterial injury PT CTCAE_v5 ctcae5:C145943 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Breast Injury, CTCAE Grade 4 Intraoperative breast injury 10065831 C145943 Grade 4 Intraoperative breast injury Grade 4 Intraoperative breast injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Breast Injury, CTCAE PT NCI Grade 4 Intraoperative breast injury PT CTCAE_v5 ctcae5:C145944 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Cardiac Injury, CTCAE Grade 4 Intraoperative cardiac injury 10065843 C145944 Grade 4 Intraoperative cardiac injury Grade 4 Intraoperative cardiac injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Cardiac Injury, CTCAE PT NCI Grade 4 Intraoperative cardiac injury PT CTCAE_v5 ctcae5:C145945 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Ear Injury, CTCAE Grade 4 Intraoperative ear injury 10065844 C145945 Grade 4 Intraoperative ear injury Grade 4 Intraoperative ear injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Ear Injury, CTCAE PT NCI Grade 4 Intraoperative ear injury PT CTCAE_v5 ctcae5:C145946 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Endocrine Injury, CTCAE Grade 4 Intraoperative endocrine injury 10065834 C145946 Grade 4 Intraoperative endocrine injury Grade 4 Intraoperative endocrine injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Endocrine Injury, CTCAE PT NCI Grade 4 Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C145947 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Gastrointestinal Injury, CTCAE Grade 4 Intraoperative gastrointestinal injury 10065825 C145947 Grade 4 Intraoperative gastrointestinal injury Grade 4 Intraoperative gastrointestinal injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Grade 4 Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C145948 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Head and Neck Injury, CTCAE Grade 4 Intraoperative head and neck injury 10065842 C145948 Grade 4 Intraoperative head and neck injury Grade 4 Intraoperative head and neck injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Head and Neck Injury, CTCAE PT NCI Grade 4 Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C145949 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Hemorrhage, CTCAE Grade 4 Intraoperative hemorrhage 10055298 C145949 Grade 4 Intraoperative hemorrhage Grade 4 Intraoperative hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Hemorrhage, CTCAE PT NCI Grade 4 Intraoperative hemorrhage PT CTCAE_v5 ctcae5:C145950 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Hepatobiliary Injury, CTCAE Grade 4 Intraoperative hepatobiliary injury 10065827 C145950 Grade 4 Intraoperative hepatobiliary injury Grade 4 Intraoperative hepatobiliary injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Grade 4 Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C145951 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Musculoskeletal Injury, CTCAE Grade 4 Intraoperative musculoskeletal injury 10065829 C145951 Grade 4 Intraoperative musculoskeletal injury Grade 4 Intraoperative musculoskeletal injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Grade 4 Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C145952 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Neurological Injury, CTCAE Grade 4 Intraoperative neurological injury 10065830 C145952 Grade 4 Intraoperative neurological injury Grade 4 Intraoperative neurological injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Neurological Injury, CTCAE PT NCI Grade 4 Intraoperative neurological injury PT CTCAE_v5 ctcae5:C145953 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Ocular Injury, CTCAE Grade 4 Intraoperative ocular injury 10065841 C145953 Grade 4 Intraoperative ocular injury Grade 4 Intraoperative ocular injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Ocular Injury, CTCAE PT NCI Grade 4 Intraoperative ocular injury PT CTCAE_v5 ctcae5:C145954 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Renal Injury, CTCAE Grade 4 Intraoperative renal injury 10065845 C145954 Grade 4 Intraoperative renal injury Grade 4 Intraoperative renal injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Renal Injury, CTCAE PT NCI Grade 4 Intraoperative renal injury PT CTCAE_v5 ctcae5:C145955 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Reproductive Tract Injury, CTCAE Grade 4 Intraoperative reproductive tract injury 10065840 C145955 Grade 4 Intraoperative reproductive tract injury Grade 4 Intraoperative reproductive tract injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Grade 4 Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C145956 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Respiratory Injury, CTCAE Grade 4 Intraoperative respiratory injury 10065832 C145956 Grade 4 Intraoperative respiratory injury Grade 4 Intraoperative respiratory injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Respiratory Injury, CTCAE PT NCI Grade 4 Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C145957 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Splenic Injury, CTCAE Grade 4 Intraoperative splenic injury 10065847 C145957 Grade 4 Intraoperative splenic injury Grade 4 Intraoperative splenic injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Splenic Injury, CTCAE PT NCI Grade 4 Intraoperative splenic injury PT CTCAE_v5 ctcae5:C145958 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Urinary Injury, CTCAE Grade 4 Intraoperative urinary injury 10065828 C145958 Grade 4 Intraoperative urinary injury Grade 4 Intraoperative urinary injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Urinary Injury, CTCAE PT NCI Grade 4 Intraoperative urinary injury PT CTCAE_v5 ctcae5:C145959 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Intraoperative Venous Injury, CTCAE Grade 4 Intraoperative venous injury 10065848 C145959 Grade 4 Intraoperative venous injury Grade 4 Intraoperative venous injury Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Intraoperative Venous Injury, CTCAE PT NCI Grade 4 Intraoperative venous injury PT CTCAE_v5 ctcae5:C145960 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Investigations - Other, Specify, CTCAE Grade 4 Investigations - Other, specify 10022891 C145960 Grade 4 Investigations - Other, specify Grade 4 Investigations - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Investigations - Other, Specify, CTCAE PT NCI Grade 4 Investigations - Other, specify PT CTCAE_v5 ctcae5:C145964 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Jejunal Perforation, CTCAE Grade 4 Jejunal perforation 10023174 C145964 Grade 4 Jejunal perforation Grade 4 Jejunal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Jejunal Perforation, CTCAE PT NCI Grade 4 Jejunal perforation PT CTCAE_v5 ctcae5:C145965 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Jejunal Stenosis, CTCAE Grade 4 Jejunal stenosis 10023176 C145965 Grade 4 Jejunal stenosis Grade 4 Jejunal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Jejunal Stenosis, CTCAE PT NCI Grade 4 Jejunal stenosis PT CTCAE_v5 ctcae5:C145967 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Joint Infection, CTCAE Grade 4 Joint infection 10023216 C145967 Grade 4 Joint infection Grade 4 Joint infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Joint Infection, CTCAE PT NCI Grade 4 Joint infection PT CTCAE_v5 ctcae5:C145968 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Kidney Anastomotic Leak, CTCAE Grade 4 Kidney anastomotic leak 10065803 C145968 Grade 4 Kidney anastomotic leak Grade 4 Kidney anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Kidney Anastomotic Leak, CTCAE PT NCI Grade 4 Kidney anastomotic leak PT CTCAE_v5 ctcae5:C145969 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Kidney Infection, CTCAE Grade 4 Kidney infection 10023424 C145969 Grade 4 Kidney infection Grade 4 Kidney infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Kidney Infection, CTCAE PT NCI Grade 4 Kidney infection PT CTCAE_v5 ctcae5:C145970 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Large Intestinal Anastomotic Leak, CTCAE Grade 4 Large intestinal anastomotic leak 10065891 C145970 Grade 4 Large intestinal anastomotic leak Grade 4 Large intestinal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Large Intestinal Anastomotic Leak, CTCAE PT NCI Grade 4 Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C145971 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Laryngeal Edema, CTCAE Grade 4 Laryngeal edema 10023838 C145971 Grade 4 Laryngeal edema Grade 4 Laryngeal edema Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Laryngeal Edema, CTCAE PT NCI Grade 4 Laryngeal edema PT CTCAE_v5 ctcae5:C145974 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Laryngeal Mucositis, CTCAE Grade 4 Laryngeal mucositis 10065880 C145974 Grade 4 Laryngeal mucositis Grade 4 Laryngeal mucositis Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Laryngeal Mucositis, CTCAE PT NCI Grade 4 Laryngeal mucositis PT CTCAE_v5 ctcae5:C145975 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Laryngeal Obstruction, CTCAE Grade 4 Laryngeal obstruction 10059639 C145975 Grade 4 Laryngeal obstruction Grade 4 Laryngeal obstruction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Laryngeal Obstruction, CTCAE PT NCI Grade 4 Laryngeal obstruction PT CTCAE_v5 ctcae5:C145976 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Laryngeal Stenosis, CTCAE Grade 4 Laryngeal stenosis 10023862 C145976 Grade 4 Laryngeal stenosis Grade 4 Laryngeal stenosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Laryngeal Stenosis, CTCAE PT NCI Grade 4 Laryngeal stenosis PT CTCAE_v5 ctcae5:C145977 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Laryngitis Grade 4 Laryngitis, CTCAE 10023874 C145977 Grade 4 Laryngitis Grade 4 Laryngitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Laryngitis PT CTCAE_v5 Grade 4 Laryngitis, CTCAE PT NCI ctcae5:C145978 Life-threatening consequences Life-threatening consequences Grade 4 Laryngopharyngeal Dysesthesia, CTCAE Grade 4 Laryngopharyngeal dysesthesia 10062667 C145978 Grade 4 Laryngopharyngeal dysesthesia Grade 4 Laryngopharyngeal dysesthesia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Grade 4 Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C145979 Persistent or severe episodes associated with syncope; urgent intervention indicated (e.g., fiberoptic laryngoscopy, intubation, botox injection) Persistent or severe episodes associated with syncope; urgent intervention indicated (e.g., fiberoptic laryngoscopy, intubation, botox injection) Grade 4 Laryngospasm Grade 4 Laryngospasm, CTCAE 10023891 C145979 Grade 4 Laryngospasm Grade 4 Laryngospasm Persistent or severe episodes associated with syncope; urgent intervention indicated (e.g., fiberoptic laryngoscopy, intubation, botox injection) NCI Persistent or severe episodes associated with syncope; urgent intervention indicated (e.g., fiberoptic laryngoscopy, intubation, botox injection) CTCAE_v5 Grade 4 Laryngospasm PT CTCAE_v5 Grade 4 Laryngospasm, CTCAE PT NCI ctcae5:C145980 Present Present Grade 4 Leukemia Secondary To Oncology Chemotherapy, CTCAE Grade 4 Leukemia secondary to oncology chemotherapy 10048293 C145980 Grade 4 Leukemia secondary to oncology chemotherapy Grade 4 Leukemia secondary to oncology chemotherapy Present NCI Present CTCAE_v5 Grade 4 Leukemia Secondary To Oncology Chemotherapy, CTCAE PT NCI Grade 4 Leukemia secondary to oncology chemotherapy PT CTCAE_v5 ctcae5:C145981 Clinical manifestations of leucostasis; urgent intervention indicated Clinical manifestations of leucostasis; urgent intervention indicated Grade 4 Leukocytosis Grade 4 Leukocytosis, CTCAE 10024378 C145981 Grade 4 Leukocytosis Grade 4 Leukocytosis Clinical manifestations of leucostasis; urgent intervention indicated NCI Clinical manifestations of leucostasis; urgent intervention indicated CTCAE_v5 Grade 4 Leukocytosis PT CTCAE_v5 Grade 4 Leukocytosis, CTCAE PT NCI ctcae5:C145982 Life-threatening consequences; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving most of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly Life-threatening consequences; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving most of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly Grade 4 Leukoencephalopathy Grade 4 Leukoencephalopathy, CTCAE 10024382 C145982 Grade 4 Leukoencephalopathy Grade 4 Leukoencephalopathy Life-threatening consequences; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving most of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly NCI Life-threatening consequences; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving most of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly CTCAE_v5 Grade 4 Leukoencephalopathy PT CTCAE_v5 Grade 4 Leukoencephalopathy, CTCAE PT NCI ctcae5:C145983 >5.0 x ULN and with signs or symptoms >5.0 x ULN and with signs or symptoms Grade 4 Lipase Increased, CTCAE Grade 4 Lipase increased 10024574 C145983 Grade 4 Lipase increased Grade 4 Lipase increased >5.0 x ULN and with signs or symptoms NCI >5.0 x ULN and with signs or symptoms CTCAE_v5 Grade 4 Lipase Increased, CTCAE PT NCI Grade 4 Lipase increased PT CTCAE_v5 ctcae5:C145984 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Lower Gastrointestinal Hemorrhage, CTCAE Grade 4 Lower gastrointestinal hemorrhage 10051746 C145984 Grade 4 Lower gastrointestinal hemorrhage Grade 4 Lower gastrointestinal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 4 Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C145985 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Lung Infection, CTCAE Grade 4 Lung infection 10061229 C145985 Grade 4 Lung infection Grade 4 Lung infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Lung Infection, CTCAE PT NCI Grade 4 Lung infection PT CTCAE_v5 ctcae5:C145986 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Lymph Gland Infection, CTCAE Grade 4 Lymph gland infection 10050823 C145986 Grade 4 Lymph gland infection Grade 4 Lymph gland infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Lymph Gland Infection, CTCAE PT NCI Grade 4 Lymph gland infection PT CTCAE_v5 ctcae5:C145987 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Lymph Leakage, CTCAE Grade 4 Lymph leakage 10065773 C145987 Grade 4 Lymph leakage Grade 4 Lymph leakage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Lymph Leakage, CTCAE PT NCI Grade 4 Lymph leakage PT CTCAE_v5 ctcae5:C145988 <200/mm3; <0.2 x 10e9/L <200/mm3; <0.2 x 10e9/L Grade 4 Lymphocyte Count Decreased, CTCAE Grade 4 Lymphocyte count decreased 10025256 C145988 Grade 4 Lymphocyte count decreased Grade 4 Lymphocyte count decreased <200/mm3; <0.2 x 10e9/L NCI <200/mm3; <0.2 x 10e9/L CTCAE_v5 Grade 4 Lymphocyte Count Decreased, CTCAE PT NCI Grade 4 Lymphocyte count decreased PT CTCAE_v5 ctcae5:C145989 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Mania Grade 4 Mania, CTCAE 10026749 C145989 Grade 4 Mania Grade 4 Mania Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Mania PT CTCAE_v5 Grade 4 Mania, CTCAE PT NCI ctcae5:C145991 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mediastinal Infection, CTCAE Grade 4 Mediastinal infection 10057483 C145991 Grade 4 Mediastinal infection Grade 4 Mediastinal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mediastinal Infection, CTCAE PT NCI Grade 4 Mediastinal infection PT CTCAE_v5 ctcae5:C145992 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Meningismus Grade 4 Meningismus, CTCAE 10027198 C145992 Grade 4 Meningismus Grade 4 Meningismus Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Meningismus PT CTCAE_v5 Grade 4 Meningismus, CTCAE PT NCI ctcae5:C145993 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Meningitis Grade 4 Meningitis, CTCAE 10027199 C145993 Grade 4 Meningitis Grade 4 Meningitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Meningitis PT CTCAE_v5 Grade 4 Meningitis, CTCAE PT NCI ctcae5:C145994 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Menorrhagia Grade 4 Menorrhagia, CTCAE 10027313 C145994 Grade 4 Menorrhagia Grade 4 Menorrhagia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Menorrhagia PT CTCAE_v5 Grade 4 Menorrhagia, CTCAE PT NCI ctcae5:C145995 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Grade 4 Metabolism and nutrition disorders - Other, specify 10027433 C145995 Grade 4 Metabolism and nutrition disorders - Other, specify Grade 4 Metabolism and nutrition disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Grade 4 Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C145996 Life-threatening consequences Life-threatening consequences Grade 4 Methemoglobinemia Grade 4 Methemoglobinemia, CTCAE 10027506 C145996 Grade 4 Methemoglobinemia Grade 4 Methemoglobinemia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Methemoglobinemia PT CTCAE_v5 Grade 4 Methemoglobinemia, CTCAE PT NCI ctcae5:C145997 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Middle Ear Inflammation, CTCAE Grade 4 Middle ear inflammation 10065838 C145997 Grade 4 Middle ear inflammation Grade 4 Middle ear inflammation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Middle Ear Inflammation, CTCAE PT NCI Grade 4 Middle ear inflammation PT CTCAE_v5 ctcae5:C145998 Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Grade 4 Mitral Valve Disease, CTCAE Grade 4 Mitral valve disease 10061532 C145998 Grade 4 Mitral valve disease Grade 4 Mitral valve disease Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) NCI Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) CTCAE_v5 Grade 4 Mitral Valve Disease, CTCAE PT NCI Grade 4 Mitral valve disease PT CTCAE_v5 ctcae5:C146001 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mucosal Infection, CTCAE Grade 4 Mucosal infection 10065764 C146001 Grade 4 Mucosal infection Grade 4 Mucosal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mucosal Infection, CTCAE PT NCI Grade 4 Mucosal infection PT CTCAE_v5 ctcae5:C146002 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mucositis Oral, CTCAE Grade 4 Mucositis oral 10028130 C146002 Grade 4 Mucositis oral Grade 4 Mucositis oral Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mucositis Oral, CTCAE PT NCI Grade 4 Mucositis oral PT CTCAE_v5 ctcae5:C146003 Life-threatening consequences (e.g., vasopressor dependent and oliguric or anuric or ischemic colitis or lactic acidosis) Life-threatening consequences (e.g., vasopressor dependent and oliguric or anuric or ischemic colitis or lactic acidosis) Grade 4 Multi-Organ Failure, CTCAE Grade 4 Multi-organ failure 10028154 C146003 Grade 4 Multi-organ failure Grade 4 Multi-organ failure Life-threatening consequences (e.g., vasopressor dependent and oliguric or anuric or ischemic colitis or lactic acidosis) NCI Life-threatening consequences (e.g., vasopressor dependent and oliguric or anuric or ischemic colitis or lactic acidosis) CTCAE_v5 Grade 4 Multi-Organ Failure, CTCAE PT NCI Grade 4 Multi-organ failure PT CTCAE_v5 ctcae5:C146004 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Grade 4 Musculoskeletal and connective tissue disorder - Other, specify 10028395 C146004 Grade 4 Musculoskeletal and connective tissue disorder - Other, specify Grade 4 Musculoskeletal and connective tissue disorder - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Grade 4 Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C146005 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Myasthenia Gravis, CTCAE Grade 4 Myasthenia gravis 10028417 C146005 Grade 4 Myasthenia gravis Grade 4 Myasthenia gravis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Myasthenia Gravis, CTCAE PT NCI Grade 4 Myasthenia gravis PT CTCAE_v5 ctcae5:C146006 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Myelodysplastic Syndrome, CTCAE Grade 4 Myelodysplastic syndrome 10028533 C146006 Grade 4 Myelodysplastic syndrome Grade 4 Myelodysplastic syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Myelodysplastic Syndrome, CTCAE PT NCI Grade 4 Myelodysplastic syndrome PT CTCAE_v5 ctcae5:C146007 Life-threatening consequences; hemodynamically unstable Life-threatening consequences; hemodynamically unstable Grade 4 Myocardial Infarction, CTCAE Grade 4 Myocardial infarction 10028596 C146007 Grade 4 Myocardial infarction Grade 4 Myocardial infarction Life-threatening consequences; hemodynamically unstable NCI Life-threatening consequences; hemodynamically unstable CTCAE_v5 Grade 4 Myocardial Infarction, CTCAE PT NCI Grade 4 Myocardial infarction PT CTCAE_v5 ctcae5:C146008 Vascular or respiratory impairment requiring urgent intervention Vascular or respiratory impairment requiring urgent intervention Grade 4 Neck Edema, CTCAE Grade 4 Neck edema 10054482 C146008 Grade 4 Neck edema Grade 4 Neck edema Vascular or respiratory impairment requiring urgent intervention NCI Vascular or respiratory impairment requiring urgent intervention CTCAE_v5 Grade 4 Neck Edema, CTCAE PT NCI Grade 4 Neck edema PT CTCAE_v5 ctcae5:C146009 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Grade 4 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C146009 Grade 4 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Grade 4 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Grade 4 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C146010 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Nephrotic Syndrome, CTCAE Grade 4 Nephrotic syndrome 10029164 C146010 Grade 4 Nephrotic syndrome Grade 4 Nephrotic syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Nephrotic Syndrome, CTCAE PT NCI Grade 4 Nephrotic syndrome PT CTCAE_v5 ctcae5:C146011 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Nervous System Disorders - Other, Specify, CTCAE Grade 4 Nervous system disorders - Other, specify 10029205 C146011 Grade 4 Nervous system disorders - Other, specify Grade 4 Nervous system disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Nervous System Disorders - Other, Specify, CTCAE PT NCI Grade 4 Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C146012 <500/mm3; <0.5 x 10e9/L <500/mm3; <0.5 x 10e9/L Grade 4 Neutrophil Count Decreased, CTCAE Grade 4 Neutrophil count decreased 10029366 C146012 Grade 4 Neutrophil count decreased Grade 4 Neutrophil count decreased <500/mm3; <0.5 x 10e9/L NCI <500/mm3; <0.5 x 10e9/L CTCAE_v5 Grade 4 Neutrophil Count Decreased, CTCAE PT NCI Grade 4 Neutrophil count decreased PT CTCAE_v5 ctcae5:C146013 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Night Blindness, CTCAE Grade 4 Night blindness 10029404 C146013 Grade 4 Night blindness Grade 4 Night blindness Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Night Blindness, CTCAE PT NCI Grade 4 Night blindness PT CTCAE_v5 ctcae5:C146014 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Obstruction Gastric, CTCAE Grade 4 Obstruction gastric 10029957 C146014 Grade 4 Obstruction gastric Grade 4 Obstruction gastric Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Obstruction Gastric, CTCAE PT NCI Grade 4 Obstruction gastric PT CTCAE_v5 ctcae5:C146015 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Optic Nerve Disorder, CTCAE Grade 4 Optic nerve disorder 10061322 C146015 Grade 4 Optic nerve disorder Grade 4 Optic nerve disorder Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Optic Nerve Disorder, CTCAE PT NCI Grade 4 Optic nerve disorder PT CTCAE_v5 ctcae5:C146016 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Oral Cavity Fistula, CTCAE Grade 4 Oral cavity fistula 10065720 C146016 Grade 4 Oral cavity fistula Grade 4 Oral cavity fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Oral Cavity Fistula, CTCAE PT NCI Grade 4 Oral cavity fistula PT CTCAE_v5 ctcae5:C146018 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Osteonecrosis of Jaw, CTCAE Grade 4 Osteonecrosis of jaw 10064658 C146018 Grade 4 Osteonecrosis of jaw Grade 4 Osteonecrosis of jaw Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Osteonecrosis of Jaw, CTCAE PT NCI Grade 4 Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C146019 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Osteonecrosis Grade 4 Osteonecrosis, CTCAE 10031264 C146019 Grade 4 Osteonecrosis Grade 4 Osteonecrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Osteonecrosis PT CTCAE_v5 Grade 4 Osteonecrosis, CTCAE PT NCI ctcae5:C146020 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Otitis Externa, CTCAE Grade 4 Otitis externa 10033072 C146020 Grade 4 Otitis externa Grade 4 Otitis externa Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Otitis Externa, CTCAE PT NCI Grade 4 Otitis externa PT CTCAE_v5 ctcae5:C146021 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Otitis Media, CTCAE Grade 4 Otitis media 10033078 C146021 Grade 4 Otitis media Grade 4 Otitis media Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Otitis Media, CTCAE PT NCI Grade 4 Otitis media PT CTCAE_v5 ctcae5:C146023 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ovarian Infection, CTCAE Grade 4 Ovarian infection 10055005 C146023 Grade 4 Ovarian infection Grade 4 Ovarian infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ovarian Infection, CTCAE PT NCI Grade 4 Ovarian infection PT CTCAE_v5 ctcae5:C146024 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ovarian Rupture, CTCAE Grade 4 Ovarian rupture 10033279 C146024 Grade 4 Ovarian rupture Grade 4 Ovarian rupture Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ovarian Rupture, CTCAE PT NCI Grade 4 Ovarian rupture PT CTCAE_v5 ctcae5:C146025 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pancreas Infection, CTCAE Grade 4 Pancreas infection 10051741 C146025 Grade 4 Pancreas infection Grade 4 Pancreas infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pancreas Infection, CTCAE PT NCI Grade 4 Pancreas infection PT CTCAE_v5 ctcae5:C146026 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Pancreatic Anastomotic Leak, CTCAE Grade 4 Pancreatic anastomotic leak 10050457 C146026 Grade 4 Pancreatic anastomotic leak Grade 4 Pancreatic anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Pancreatic Anastomotic Leak, CTCAE PT NCI Grade 4 Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C146027 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Pancreatic Duct Stenosis, CTCAE Grade 4 Pancreatic duct stenosis 10065703 C146027 Grade 4 Pancreatic duct stenosis Grade 4 Pancreatic duct stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Pancreatic Duct Stenosis, CTCAE PT NCI Grade 4 Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C146030 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Pancreatic Necrosis, CTCAE Grade 4 Pancreatic necrosis 10058096 C146030 Grade 4 Pancreatic necrosis Grade 4 Pancreatic necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Pancreatic Necrosis, CTCAE PT NCI Grade 4 Pancreatic necrosis PT CTCAE_v5 ctcae5:C146031 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Papilledema Grade 4 Papilledema, CTCAE 10033703 C146031 Grade 4 Papilledema Grade 4 Papilledema Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Papilledema PT CTCAE_v5 Grade 4 Papilledema, CTCAE PT NCI ctcae5:C146032 Life-threatening consequences Life-threatening consequences Grade 4 Papulopustular Rash, CTCAE Grade 4 Papulopustular rash 10069138 C146032 Grade 4 Papulopustular rash Grade 4 Papulopustular rash Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Papulopustular Rash, CTCAE PT NCI Grade 4 Papulopustular rash PT CTCAE_v5 ctcae5:C146033 Life-threatening consequences; incompletely controlled medically; cardioversion indicated Life-threatening consequences; incompletely controlled medically; cardioversion indicated Grade 4 Paroxysmal Atrial Tachycardia, CTCAE Grade 4 Paroxysmal atrial tachycardia 10034040 C146033 Grade 4 Paroxysmal atrial tachycardia Grade 4 Paroxysmal atrial tachycardia Life-threatening consequences; incompletely controlled medically; cardioversion indicated NCI Life-threatening consequences; incompletely controlled medically; cardioversion indicated CTCAE_v5 Grade 4 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Grade 4 Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C146034 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pelvic Infection, CTCAE Grade 4 Pelvic infection 10058674 C146034 Grade 4 Pelvic infection Grade 4 Pelvic infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pelvic Infection, CTCAE PT NCI Grade 4 Pelvic infection PT CTCAE_v5 ctcae5:C146035 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Penile Infection, CTCAE Grade 4 Penile infection 10061912 C146035 Grade 4 Penile infection Grade 4 Penile infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Penile Infection, CTCAE PT NCI Grade 4 Penile infection PT CTCAE_v5 ctcae5:C146036 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Perforation Bile Duct, CTCAE Grade 4 Perforation bile duct 10034405 C146036 Grade 4 Perforation bile duct Grade 4 Perforation bile duct Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Perforation Bile Duct, CTCAE PT NCI Grade 4 Perforation bile duct PT CTCAE_v5 ctcae5:C146037 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pericardial Effusion, CTCAE Grade 4 Pericardial effusion 10034474 C146037 Grade 4 Pericardial effusion Grade 4 Pericardial effusion Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pericardial Effusion, CTCAE PT NCI Grade 4 Pericardial effusion PT CTCAE_v5 ctcae5:C146038 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pericardial Tamponade, CTCAE Grade 4 Pericardial tamponade 10053565 C146038 Grade 4 Pericardial tamponade Grade 4 Pericardial tamponade Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pericardial Tamponade, CTCAE PT NCI Grade 4 Pericardial tamponade PT CTCAE_v5 ctcae5:C146039 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Periorbital Infection, CTCAE Grade 4 Periorbital infection 10051472 C146039 Grade 4 Periorbital infection Grade 4 Periorbital infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Periorbital Infection, CTCAE PT NCI Grade 4 Periorbital infection PT CTCAE_v5 ctcae5:C146040 Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Grade 4 Peripheral Ischemia, CTCAE Grade 4 Peripheral ischemia 10034578 C146040 Grade 4 Peripheral ischemia Grade 4 Peripheral ischemia Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated NCI Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated CTCAE_v5 Grade 4 Peripheral Ischemia, CTCAE PT NCI Grade 4 Peripheral ischemia PT CTCAE_v5 ctcae5:C146041 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Peripheral Motor Neuropathy, CTCAE Grade 4 Peripheral motor neuropathy 10034580 C146041 Grade 4 Peripheral motor neuropathy Grade 4 Peripheral motor neuropathy Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Peripheral Motor Neuropathy, CTCAE PT NCI Grade 4 Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C146042 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Peripheral Nerve Infection, CTCAE Grade 4 Peripheral nerve infection 10065766 C146042 Grade 4 Peripheral nerve infection Grade 4 Peripheral nerve infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Peripheral Nerve Infection, CTCAE PT NCI Grade 4 Peripheral nerve infection PT CTCAE_v5 ctcae5:C146043 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Peripheral Sensory Neuropathy, CTCAE Grade 4 Peripheral sensory neuropathy 10034620 C146043 Grade 4 Peripheral sensory neuropathy Grade 4 Peripheral sensory neuropathy Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Peripheral Sensory Neuropathy, CTCAE PT NCI Grade 4 Peripheral sensory neuropathy PT CTCAE_v5 ctcae5:C146044 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Peritoneal Infection, CTCAE Grade 4 Peritoneal infection 10057262 C146044 Grade 4 Peritoneal infection Grade 4 Peritoneal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Peritoneal Infection, CTCAE PT NCI Grade 4 Peritoneal infection PT CTCAE_v5 ctcae5:C146046 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Personality Change, CTCAE Grade 4 Personality change 10034719 C146046 Grade 4 Personality change Grade 4 Personality change Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Personality Change, CTCAE PT NCI Grade 4 Personality change PT CTCAE_v5 ctcae5:C146047 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Pharyngeal Anastomotic Leak, CTCAE Grade 4 Pharyngeal anastomotic leak 10065705 C146047 Grade 4 Pharyngeal anastomotic leak Grade 4 Pharyngeal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Pharyngeal Anastomotic Leak, CTCAE PT NCI Grade 4 Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C146050 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pharyngeal Mucositis, CTCAE Grade 4 Pharyngeal mucositis 10065881 C146050 Grade 4 Pharyngeal mucositis Grade 4 Pharyngeal mucositis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pharyngeal Mucositis, CTCAE PT NCI Grade 4 Pharyngeal mucositis PT CTCAE_v5 ctcae5:C146052 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Pharyngeal Stenosis, CTCAE Grade 4 Pharyngeal stenosis 10050028 C146052 Grade 4 Pharyngeal stenosis Grade 4 Pharyngeal stenosis Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Pharyngeal Stenosis, CTCAE PT NCI Grade 4 Pharyngeal stenosis PT CTCAE_v5 ctcae5:C146053 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pharyngitis Grade 4 Pharyngitis, CTCAE 10034835 C146053 Grade 4 Pharyngitis Grade 4 Pharyngitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pharyngitis PT CTCAE_v5 Grade 4 Pharyngitis, CTCAE PT NCI ctcae5:C146054 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Phlebitis Infective, CTCAE Grade 4 Phlebitis infective 10056627 C146054 Grade 4 Phlebitis infective Grade 4 Phlebitis infective Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Phlebitis Infective, CTCAE PT NCI Grade 4 Phlebitis infective PT CTCAE_v5 ctcae5:C146055 <25,000/mm3; <25.0 x 10e9/L <25,000/mm3; <25.0 x 10e9/L Grade 4 Platelet Count Decreased, CTCAE Grade 4 Platelet count decreased 10035528 C146055 Grade 4 Platelet count decreased Grade 4 Platelet count decreased <25,000/mm3; <25.0 x 10e9/L NCI <25,000/mm3; <25.0 x 10e9/L CTCAE_v5 Grade 4 Platelet Count Decreased, CTCAE PT NCI Grade 4 Platelet count decreased PT CTCAE_v5 ctcae5:C146056 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Pleural Effusion, CTCAE Grade 4 Pleural effusion 10035598 C146056 Grade 4 Pleural effusion Grade 4 Pleural effusion Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Pleural Effusion, CTCAE PT NCI Grade 4 Pleural effusion PT CTCAE_v5 ctcae5:C146058 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pleural Infection, CTCAE Grade 4 Pleural infection 10061351 C146058 Grade 4 Pleural infection Grade 4 Pleural infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pleural Infection, CTCAE PT NCI Grade 4 Pleural infection PT CTCAE_v5 ctcae5:C146059 Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Pneumonitis Grade 4 Pneumonitis, CTCAE 10035742 C146059 Grade 4 Pneumonitis Grade 4 Pneumonitis Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Pneumonitis PT CTCAE_v5 Grade 4 Pneumonitis, CTCAE PT NCI ctcae5:C146060 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Portal Hypertension, CTCAE Grade 4 Portal hypertension 10036200 C146060 Grade 4 Portal hypertension Grade 4 Portal hypertension Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Portal Hypertension, CTCAE PT NCI Grade 4 Portal hypertension PT CTCAE_v5 ctcae5:C146061 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Portal Vein Thrombosis, CTCAE Grade 4 Portal vein thrombosis 10036206 C146061 Grade 4 Portal vein thrombosis Grade 4 Portal vein thrombosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Portal Vein Thrombosis, CTCAE PT NCI Grade 4 Portal vein thrombosis PT CTCAE_v5 ctcae5:C146062 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Postoperative Hemorrhage, CTCAE Grade 4 Postoperative hemorrhage 10055322 C146062 Grade 4 Postoperative hemorrhage Grade 4 Postoperative hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Postoperative Hemorrhage, CTCAE PT NCI Grade 4 Postoperative hemorrhage PT CTCAE_v5 ctcae5:C146063 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Postoperative Thoracic Procedure Complication, CTCAE Grade 4 Postoperative thoracic procedure complication 10056745 C146063 Grade 4 Postoperative thoracic procedure complication Grade 4 Postoperative thoracic procedure complication Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Postoperative Thoracic Procedure Complication, CTCAE PT NCI Grade 4 Postoperative thoracic procedure complication PT CTCAE_v5 ctcae5:C146064 Fetal loss at any gestational age Fetal loss at any gestational age Grade 4 Pregnancy Loss, CTCAE Grade 4 Pregnancy loss 10072314 C146064 Grade 4 Pregnancy loss Grade 4 Pregnancy loss Fetal loss at any gestational age NCI Fetal loss at any gestational age CTCAE_v5 Grade 4 Pregnancy Loss, CTCAE PT NCI Grade 4 Pregnancy loss PT CTCAE_v5 ctcae5:C146065 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Grade 4 Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C146065 Grade 4 Pregnancy, puerperium and perinatal conditions - Other, specify Grade 4 Pregnancy, puerperium and perinatal conditions - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Grade 4 Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C146066 Delivery of a liveborn infant at 24 weeks of gestation or less Delivery of a liveborn infant at 24 weeks of gestation or less Grade 4 Premature Delivery, CTCAE Grade 4 Premature delivery 10036595 C146066 Grade 4 Premature delivery Grade 4 Premature delivery Delivery of a liveborn infant at 24 weeks of gestation or less NCI Delivery of a liveborn infant at 24 weeks of gestation or less CTCAE_v5 Grade 4 Premature Delivery, CTCAE PT NCI Grade 4 Premature delivery PT CTCAE_v5 ctcae5:C146067 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Prolapse of Intestinal Stoma, CTCAE Grade 4 Prolapse of intestinal stoma 10065745 C146067 Grade 4 Prolapse of intestinal stoma Grade 4 Prolapse of intestinal stoma Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Prolapse of Intestinal Stoma, CTCAE PT NCI Grade 4 Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C146068 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Prolapse of Urostomy, CTCAE Grade 4 Prolapse of urostomy 10065822 C146068 Grade 4 Prolapse of urostomy Grade 4 Prolapse of urostomy Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Prolapse of Urostomy, CTCAE PT NCI Grade 4 Prolapse of urostomy PT CTCAE_v5 ctcae5:C146069 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Prostate Infection, CTCAE Grade 4 Prostate infection 10050662 C146069 Grade 4 Prostate infection Grade 4 Prostate infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Prostate Infection, CTCAE PT NCI Grade 4 Prostate infection PT CTCAE_v5 ctcae5:C146071 Life-threatening consequences; hospitalization or urgent intervention indicated Life-threatening consequences; hospitalization or urgent intervention indicated Grade 4 Psychiatric Disorders - Other, Specify, CTCAE Grade 4 Psychiatric disorders - Other, specify 10037175 C146071 Grade 4 Psychiatric disorders - Other, specify Grade 4 Psychiatric disorders - Other, specify Life-threatening consequences; hospitalization or urgent intervention indicated NCI Life-threatening consequences; hospitalization or urgent intervention indicated CTCAE_v5 Grade 4 Psychiatric Disorders - Other, Specify, CTCAE PT NCI Grade 4 Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C146072 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Psychosis Grade 4 Psychosis, CTCAE 10037234 C146072 Grade 4 Psychosis Grade 4 Psychosis Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Psychosis PT CTCAE_v5 Grade 4 Psychosis, CTCAE PT NCI ctcae5:C146073 Life-threatening respiratory compromise; urgent intervention or intubation with ventilatory support indicated Life-threatening respiratory compromise; urgent intervention or intubation with ventilatory support indicated Grade 4 Pulmonary Edema, CTCAE Grade 4 Pulmonary edema 10037375 C146073 Grade 4 Pulmonary edema Grade 4 Pulmonary edema Life-threatening respiratory compromise; urgent intervention or intubation with ventilatory support indicated NCI Life-threatening respiratory compromise; urgent intervention or intubation with ventilatory support indicated CTCAE_v5 Grade 4 Pulmonary Edema, CTCAE PT NCI Grade 4 Pulmonary edema PT CTCAE_v5 ctcae5:C146074 Life-threatening consequences (e.g., hemodynamic/pulmonary complications); intubation with ventilatory support indicated; radiographic pulmonary fibrosis >75% with severe honeycombing Life-threatening consequences (e.g., hemodynamic/pulmonary complications); intubation with ventilatory support indicated; radiographic pulmonary fibrosis >75% with severe honeycombing Grade 4 Pulmonary Fibrosis, CTCAE Grade 4 Pulmonary fibrosis 10037383 C146074 Grade 4 Pulmonary fibrosis Grade 4 Pulmonary fibrosis Life-threatening consequences (e.g., hemodynamic/pulmonary complications); intubation with ventilatory support indicated; radiographic pulmonary fibrosis >75% with severe honeycombing NCI Life-threatening consequences (e.g., hemodynamic/pulmonary complications); intubation with ventilatory support indicated; radiographic pulmonary fibrosis >75% with severe honeycombing CTCAE_v5 Grade 4 Pulmonary Fibrosis, CTCAE PT NCI Grade 4 Pulmonary fibrosis PT CTCAE_v5 ctcae5:C146075 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pulmonary Fistula, CTCAE Grade 4 Pulmonary fistula 10065873 C146075 Grade 4 Pulmonary fistula Grade 4 Pulmonary fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pulmonary Fistula, CTCAE PT NCI Grade 4 Pulmonary fistula PT CTCAE_v5 ctcae5:C146076 Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Grade 4 Pulmonary Valve Disease, CTCAE Grade 4 Pulmonary valve disease 10061541 C146076 Grade 4 Pulmonary valve disease Grade 4 Pulmonary valve disease Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) NCI Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) CTCAE_v5 Grade 4 Pulmonary Valve Disease, CTCAE PT NCI Grade 4 Pulmonary valve disease PT CTCAE_v5 ctcae5:C146077 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pyramidal Tract Syndrome, CTCAE Grade 4 Pyramidal tract syndrome 10063636 C146077 Grade 4 Pyramidal tract syndrome Grade 4 Pyramidal tract syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pyramidal Tract Syndrome, CTCAE PT NCI Grade 4 Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C146078 Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated Grade 4 Radiation Recall Reaction (Dermatologic), CTCAE Grade 4 Radiation recall reaction (dermatologic) 10037767 C146078 Grade 4 Radiation recall reaction (dermatologic) Grade 4 Radiation recall reaction (dermatologic) Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated NCI Life-threatening consequences; skin necrosis or ulceration of full thickness dermis; spontaneous bleeding from involved site; skin graft indicated CTCAE_v5 Grade 4 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Grade 4 Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C146079 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Radiculitis Grade 4 Radiculitis, CTCAE 10061928 C146079 Grade 4 Radiculitis Grade 4 Radiculitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Radiculitis PT CTCAE_v5 Grade 4 Radiculitis, CTCAE PT NCI ctcae5:C146080 Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated Grade 4 Rash Acneiform, CTCAE Grade 4 Rash acneiform 10037847 C146080 Grade 4 Rash acneiform Grade 4 Rash acneiform Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated NCI Life-threatening consequences; papules and/or pustules covering any % BSA, which may or may not be associated with symptoms of pruritus or tenderness and are associated with extensive superinfection with IV antibiotics indicated CTCAE_v5 Grade 4 Rash Acneiform, CTCAE PT NCI Grade 4 Rash acneiform PT CTCAE_v5 ctcae5:C146081 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Anastomotic Leak, CTCAE Grade 4 Rectal anastomotic leak 10065894 C146081 Grade 4 Rectal anastomotic leak Grade 4 Rectal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Anastomotic Leak, CTCAE PT NCI Grade 4 Rectal anastomotic leak PT CTCAE_v5 ctcae5:C146084 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Mucositis, CTCAE Grade 4 Rectal mucositis 10063190 C146084 Grade 4 Rectal mucositis Grade 4 Rectal mucositis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Mucositis, CTCAE PT NCI Grade 4 Rectal mucositis PT CTCAE_v5 ctcae5:C146088 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Stenosis, CTCAE Grade 4 Rectal stenosis 10038079 C146088 Grade 4 Rectal stenosis Grade 4 Rectal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Stenosis, CTCAE PT NCI Grade 4 Rectal stenosis PT CTCAE_v5 ctcae5:C146090 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Recurrent Laryngeal Nerve Palsy, CTCAE Grade 4 Recurrent laryngeal nerve palsy 10038130 C146090 Grade 4 Recurrent laryngeal nerve palsy Grade 4 Recurrent laryngeal nerve palsy Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Grade 4 Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C146091 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Renal and Urinary Disorders - Other, Specify, CTCAE Grade 4 Renal and urinary disorders - Other, specify 10038359 C146091 Grade 4 Renal and urinary disorders - Other, specify Grade 4 Renal and urinary disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Grade 4 Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C146092 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Renal Calculi, CTCAE Grade 4 Renal calculi 10038385 C146092 Grade 4 Renal calculi Grade 4 Renal calculi Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Renal Calculi, CTCAE PT NCI Grade 4 Renal calculi PT CTCAE_v5 ctcae5:C146094 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Reproductive System and Breast Disorders - Other, Specify, CTCAE Grade 4 Reproductive system and breast disorders - Other, specify 10038604 C146094 Grade 4 Reproductive system and breast disorders - Other, specify Grade 4 Reproductive system and breast disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Grade 4 Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C146095 Life-threatening consequences; urgent intervention, intubation, or ventilatory support indicated Life-threatening consequences; urgent intervention, intubation, or ventilatory support indicated Grade 4 Respiratory Failure, CTCAE Grade 4 Respiratory failure 10038695 C146095 Grade 4 Respiratory failure Grade 4 Respiratory failure Life-threatening consequences; urgent intervention, intubation, or ventilatory support indicated NCI Life-threatening consequences; urgent intervention, intubation, or ventilatory support indicated CTCAE_v5 Grade 4 Respiratory Failure, CTCAE PT NCI Grade 4 Respiratory failure PT CTCAE_v5 ctcae5:C146096 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Grade 4 Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C146096 Grade 4 Respiratory, thoracic and mediastinal disorders - Other, specify Grade 4 Respiratory, thoracic and mediastinal disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Grade 4 Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C146097 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Retroperitoneal Hemorrhage, CTCAE Grade 4 Retroperitoneal hemorrhage 10038981 C146097 Grade 4 Retroperitoneal hemorrhage Grade 4 Retroperitoneal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Retroperitoneal Hemorrhage, CTCAE PT NCI Grade 4 Retroperitoneal hemorrhage PT CTCAE_v5 ctcae5:C146098 Life-threatening consequences Life-threatening consequences Grade 4 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE Grade 4 Reversible posterior leukoencephalopathy syndrome 10063761 C146098 Grade 4 Reversible posterior leukoencephalopathy syndrome Grade 4 Reversible posterior leukoencephalopathy syndrome Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE PT NCI Grade 4 Reversible posterior leukoencephalopathy syndrome PT CTCAE_v5 ctcae5:C146099 Life-threatening consequences; dialysis Life-threatening consequences; dialysis Grade 4 Rhabdomyolysis Grade 4 Rhabdomyolysis, CTCAE 10039020 C146099 Grade 4 Rhabdomyolysis Grade 4 Rhabdomyolysis Life-threatening consequences; dialysis NCI Life-threatening consequences; dialysis CTCAE_v5 Grade 4 Rhabdomyolysis PT CTCAE_v5 Grade 4 Rhabdomyolysis, CTCAE PT NCI ctcae5:C146100 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Salivary Duct Inflammation, CTCAE Grade 4 Salivary duct inflammation 10056681 C146100 Grade 4 Salivary duct inflammation Grade 4 Salivary duct inflammation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Salivary Duct Inflammation, CTCAE PT NCI Grade 4 Salivary duct inflammation PT CTCAE_v5 ctcae5:C146101 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Salivary Gland Infection, CTCAE Grade 4 Salivary gland infection 10039413 C146101 Grade 4 Salivary gland infection Grade 4 Salivary gland infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Salivary Gland Infection, CTCAE PT NCI Grade 4 Salivary gland infection PT CTCAE_v5 ctcae5:C146102 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Scleral Disorder, CTCAE Grade 4 Scleral disorder 10061510 C146102 Grade 4 Scleral disorder Grade 4 Scleral disorder Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Scleral Disorder, CTCAE PT NCI Grade 4 Scleral disorder PT CTCAE_v5 ctcae5:C146103 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Scrotal Infection, CTCAE Grade 4 Scrotal infection 10062156 C146103 Grade 4 Scrotal infection Grade 4 Scrotal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Scrotal Infection, CTCAE PT NCI Grade 4 Scrotal infection PT CTCAE_v5 ctcae5:C146104 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Sepsis Grade 4 Sepsis, CTCAE 10040047 C146104 Grade 4 Sepsis Grade 4 Sepsis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Sepsis PT CTCAE_v5 Grade 4 Sepsis, CTCAE PT NCI ctcae5:C146105 >5.0 x ULN and with signs or symptoms >5.0 x ULN and with signs or symptoms Grade 4 Serum Amylase Increased, CTCAE Grade 4 Serum amylase increased 10040139 C146105 Grade 4 Serum amylase increased Grade 4 Serum amylase increased >5.0 x ULN and with signs or symptoms NCI >5.0 x ULN and with signs or symptoms CTCAE_v5 Grade 4 Serum Amylase Increased, CTCAE PT NCI Grade 4 Serum amylase increased PT CTCAE_v5 ctcae5:C146106 Life-threatening consequences; pressor or ventilatory support indicated Life-threatening consequences; pressor or ventilatory support indicated Grade 4 Serum Sickness, CTCAE Grade 4 Serum sickness 10040400 C146106 Grade 4 Serum sickness Grade 4 Serum sickness Life-threatening consequences; pressor or ventilatory support indicated NCI Life-threatening consequences; pressor or ventilatory support indicated CTCAE_v5 Grade 4 Serum Sickness, CTCAE PT NCI Grade 4 Serum sickness PT CTCAE_v5 ctcae5:C146107 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Shingles Grade 4 Shingles, CTCAE 10040555 C146107 Grade 4 Shingles Grade 4 Shingles Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Shingles PT CTCAE_v5 Grade 4 Shingles, CTCAE PT NCI ctcae5:C146108 Necrosis of soft tissue or bone; urgent operative intervention indicated Necrosis of soft tissue or bone; urgent operative intervention indicated Grade 4 Sinus Disorder, CTCAE Grade 4 Sinus disorder 10062244 C146108 Grade 4 Sinus disorder Grade 4 Sinus disorder Necrosis of soft tissue or bone; urgent operative intervention indicated NCI Necrosis of soft tissue or bone; urgent operative intervention indicated CTCAE_v5 Grade 4 Sinus Disorder, CTCAE PT NCI Grade 4 Sinus disorder PT CTCAE_v5 ctcae5:C146109 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Sinusitis Grade 4 Sinusitis, CTCAE 10040753 C146109 Grade 4 Sinusitis Grade 4 Sinusitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Sinusitis PT CTCAE_v5 Grade 4 Sinusitis, CTCAE PT NCI ctcae5:C146110 Life-threatening consequences (e.g., ventilatory support, dialysis, plasmapheresis, peritoneal drainage) Life-threatening consequences (e.g., ventilatory support, dialysis, plasmapheresis, peritoneal drainage) Grade 4 Sinusoidal Obstruction Syndrome, CTCAE Grade 4 Sinusoidal obstruction syndrome 10063675 C146110 Grade 4 Sinusoidal obstruction syndrome Grade 4 Sinusoidal obstruction syndrome Life-threatening consequences (e.g., ventilatory support, dialysis, plasmapheresis, peritoneal drainage) NCI Life-threatening consequences (e.g., ventilatory support, dialysis, plasmapheresis, peritoneal drainage) CTCAE_v5 Grade 4 Sinusoidal Obstruction Syndrome, CTCAE PT NCI Grade 4 Sinusoidal obstruction syndrome PT CTCAE_v5 ctcae5:C146111 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Grade 4 Skin and subcutaneous tissue disorders - Other, specify 10040785 C146111 Grade 4 Skin and subcutaneous tissue disorders - Other, specify Grade 4 Skin and subcutaneous tissue disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Grade 4 Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C146112 Generalized; associated with signs or symptoms of impaired breathing or feeding Generalized; associated with signs or symptoms of impaired breathing or feeding Grade 4 Skin Induration, CTCAE Grade 4 Skin induration 10051837 C146112 Grade 4 Skin induration Grade 4 Skin induration Generalized; associated with signs or symptoms of impaired breathing or feeding NCI Generalized; associated with signs or symptoms of impaired breathing or feeding CTCAE_v5 Grade 4 Skin Induration, CTCAE PT NCI Grade 4 Skin induration PT CTCAE_v5 ctcae5:C146113 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Skin Infection, CTCAE Grade 4 Skin infection 10040872 C146113 Grade 4 Skin infection Grade 4 Skin infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Skin Infection, CTCAE PT NCI Grade 4 Skin infection PT CTCAE_v5 ctcae5:C146114 Any size ulcer with extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss Any size ulcer with extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss Grade 4 Skin Ulceration, CTCAE Grade 4 Skin ulceration 10040947 C146114 Grade 4 Skin ulceration Grade 4 Skin ulceration Any size ulcer with extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss NCI Any size ulcer with extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss CTCAE_v5 Grade 4 Skin Ulceration, CTCAE PT NCI Grade 4 Skin ulceration PT CTCAE_v5 ctcae5:C146115 Cardiovascular or neuropsychiatric symptoms; urgent operative intervention indicated Cardiovascular or neuropsychiatric symptoms; urgent operative intervention indicated Grade 4 Sleep Apnea, CTCAE Grade 4 Sleep apnea 10040975 C146115 Grade 4 Sleep apnea Grade 4 Sleep apnea Cardiovascular or neuropsychiatric symptoms; urgent operative intervention indicated NCI Cardiovascular or neuropsychiatric symptoms; urgent operative intervention indicated CTCAE_v5 Grade 4 Sleep Apnea, CTCAE PT NCI Grade 4 Sleep apnea PT CTCAE_v5 ctcae5:C146116 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Small Intestinal Anastomotic Leak, CTCAE Grade 4 Small intestinal anastomotic leak 10065892 C146116 Grade 4 Small intestinal anastomotic leak Grade 4 Small intestinal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Small Intestinal Anastomotic Leak, CTCAE PT NCI Grade 4 Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C146117 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Small Intestinal Mucositis, CTCAE Grade 4 Small intestinal mucositis 10065710 C146117 Grade 4 Small intestinal mucositis Grade 4 Small intestinal mucositis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Small Intestinal Mucositis, CTCAE PT NCI Grade 4 Small intestinal mucositis PT CTCAE_v5 ctcae5:C146118 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Small Intestinal Obstruction, CTCAE Grade 4 Small intestinal obstruction 10041101 C146118 Grade 4 Small intestinal obstruction Grade 4 Small intestinal obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Small Intestinal Obstruction, CTCAE PT NCI Grade 4 Small intestinal obstruction PT CTCAE_v5 ctcae5:C146119 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Small Intestinal Perforation, CTCAE Grade 4 Small intestinal perforation 10041103 C146119 Grade 4 Small intestinal perforation Grade 4 Small intestinal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Small Intestinal Perforation, CTCAE PT NCI Grade 4 Small intestinal perforation PT CTCAE_v5 ctcae5:C146120 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Small Intestinal Stenosis, CTCAE Grade 4 Small intestinal stenosis 10062263 C146120 Grade 4 Small intestinal stenosis Grade 4 Small intestinal stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Small Intestinal Stenosis, CTCAE PT NCI Grade 4 Small intestinal stenosis PT CTCAE_v5 ctcae5:C146121 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Small Intestine Infection, CTCAE Grade 4 Small intestine infection 10065771 C146121 Grade 4 Small intestine infection Grade 4 Small intestine infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Small Intestine Infection, CTCAE PT NCI Grade 4 Small intestine infection PT CTCAE_v5 ctcae5:C146122 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Small Intestine Ulcer, CTCAE Grade 4 Small intestine ulcer 10041133 C146122 Grade 4 Small intestine ulcer Grade 4 Small intestine ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Small Intestine Ulcer, CTCAE PT NCI Grade 4 Small intestine ulcer PT CTCAE_v5 ctcae5:C146123 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Social Circumstances - Other, Specify, CTCAE Grade 4 Social circumstances - Other, specify 10041244 C146123 Grade 4 Social circumstances - Other, specify Grade 4 Social circumstances - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Social Circumstances - Other, Specify, CTCAE PT NCI Grade 4 Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C146124 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Soft Tissue Infection, CTCAE Grade 4 Soft tissue infection 10062255 C146124 Grade 4 Soft tissue infection Grade 4 Soft tissue infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Soft Tissue Infection, CTCAE PT NCI Grade 4 Soft tissue infection PT CTCAE_v5 ctcae5:C146125 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Soft Tissue Necrosis Lower Limb, CTCAE Grade 4 Soft tissue necrosis lower limb 10065777 C146125 Grade 4 Soft tissue necrosis lower limb Grade 4 Soft tissue necrosis lower limb Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Soft Tissue Necrosis Lower Limb, CTCAE PT NCI Grade 4 Soft tissue necrosis lower limb PT CTCAE_v5 ctcae5:C146126 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Soft Tissue Necrosis Upper Limb, CTCAE Grade 4 Soft tissue necrosis upper limb 10065778 C146126 Grade 4 Soft tissue necrosis upper limb Grade 4 Soft tissue necrosis upper limb Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Soft Tissue Necrosis Upper Limb, CTCAE PT NCI Grade 4 Soft tissue necrosis upper limb PT CTCAE_v5 ctcae5:C146127 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Somnolence Grade 4 Somnolence, CTCAE 10041349 C146127 Grade 4 Somnolence Grade 4 Somnolence Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Somnolence PT CTCAE_v5 Grade 4 Somnolence, CTCAE PT NCI ctcae5:C146128 Life-threatening consequences; unable to move active or passive range of motion Life-threatening consequences; unable to move active or passive range of motion Grade 4 Spasticity Grade 4 Spasticity, CTCAE 10041416 C146128 Grade 4 Spasticity Grade 4 Spasticity Life-threatening consequences; unable to move active or passive range of motion NCI Life-threatening consequences; unable to move active or passive range of motion CTCAE_v5 Grade 4 Spasticity PT CTCAE_v5 Grade 4 Spasticity, CTCAE PT NCI ctcae5:C146129 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Spermatic Cord Anastomotic Leak, CTCAE Grade 4 Spermatic cord anastomotic leak 10065897 C146129 Grade 4 Spermatic cord anastomotic leak Grade 4 Spermatic cord anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Grade 4 Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C146130 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Spinal Cord Compression, CTCAE Grade 4 Spinal cord compression 10041549 C146130 Grade 4 Spinal cord compression Grade 4 Spinal cord compression Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Spinal Cord Compression, CTCAE PT NCI Grade 4 Spinal cord compression PT CTCAE_v5 ctcae5:C146131 Life-threatening consequences; symptoms associated with neurovascular compromise Life-threatening consequences; symptoms associated with neurovascular compromise Grade 4 Spinal Fracture, CTCAE Grade 4 Spinal fracture 10041569 C146131 Grade 4 Spinal fracture Grade 4 Spinal fracture Life-threatening consequences; symptoms associated with neurovascular compromise NCI Life-threatening consequences; symptoms associated with neurovascular compromise CTCAE_v5 Grade 4 Spinal Fracture, CTCAE PT NCI Grade 4 Spinal fracture PT CTCAE_v5 ctcae5:C146132 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Splenic Infection, CTCAE Grade 4 Splenic infection 10062112 C146132 Grade 4 Splenic infection Grade 4 Splenic infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Splenic Infection, CTCAE PT NCI Grade 4 Splenic infection PT CTCAE_v5 ctcae5:C146133 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Stenosis of Gastrointestinal Stoma, CTCAE Grade 4 Stenosis of gastrointestinal stoma 10065898 C146133 Grade 4 Stenosis of gastrointestinal stoma Grade 4 Stenosis of gastrointestinal stoma Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Stenosis of Gastrointestinal Stoma, CTCAE PT NCI Grade 4 Stenosis of gastrointestinal stoma PT CTCAE_v5 ctcae5:C146134 Skin sloughing covering 10-30% BSA with associated signs (e.g., erythema, purpura, epidermal detachment and mucous membrane detachment) Skin sloughing covering 10-30% BSA with associated signs (e.g., erythema, purpura, epidermal detachment and mucous membrane detachment) Grade 4 Stevens-Johnson Syndrome, CTCAE Grade 4 Stevens-Johnson syndrome 10042033 C146134 Grade 4 Stevens-Johnson syndrome Grade 4 Stevens-Johnson syndrome Skin sloughing covering 10-30% BSA with associated signs (e.g., erythema, purpura, epidermal detachment and mucous membrane detachment) NCI Skin sloughing covering 10-30% BSA with associated signs (e.g., erythema, purpura, epidermal detachment and mucous membrane detachment) CTCAE_v5 Grade 4 Stevens-Johnson Syndrome, CTCAE PT NCI Grade 4 Stevens-Johnson syndrome PT CTCAE_v5 ctcae5:C146135 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Stoma Site Infection, CTCAE Grade 4 Stoma site infection 10064505 C146135 Grade 4 Stoma site infection Grade 4 Stoma site infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Stoma Site Infection, CTCAE PT NCI Grade 4 Stoma site infection PT CTCAE_v5 ctcae5:C146136 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Stridor Grade 4 Stridor, CTCAE 10042241 C146136 Grade 4 Stridor Grade 4 Stridor Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Stridor PT CTCAE_v5 Grade 4 Stridor, CTCAE PT NCI ctcae5:C146137 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Stroke Grade 4 Stroke, CTCAE 10042244 C146137 Grade 4 Stroke Grade 4 Stroke Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Stroke PT CTCAE_v5 Grade 4 Stroke, CTCAE PT NCI ctcae5:C146138 Specific plan to commit suicide with serious intent to die which requires hospitalization Specific plan to commit suicide with serious intent to die which requires hospitalization Grade 4 Suicidal Ideation, CTCAE Grade 4 Suicidal ideation 10042458 C146138 Grade 4 Suicidal ideation Grade 4 Suicidal ideation Specific plan to commit suicide with serious intent to die which requires hospitalization NCI Specific plan to commit suicide with serious intent to die which requires hospitalization CTCAE_v5 Grade 4 Suicidal Ideation, CTCAE PT NCI Grade 4 Suicidal ideation PT CTCAE_v5 ctcae5:C146139 Suicide attempt with intent to die which requires hospitalization Suicide attempt with intent to die which requires hospitalization Grade 4 Suicide Attempt, CTCAE Grade 4 Suicide attempt 10042464 C146139 Grade 4 Suicide attempt Grade 4 Suicide attempt Suicide attempt with intent to die which requires hospitalization NCI Suicide attempt with intent to die which requires hospitalization CTCAE_v5 Grade 4 Suicide Attempt, CTCAE PT NCI Grade 4 Suicide attempt PT CTCAE_v5 ctcae5:C146140 Generalized; associated with signs or symptoms of impaired breathing or feeding Generalized; associated with signs or symptoms of impaired breathing or feeding Grade 4 Superficial Soft Tissue Fibrosis, CTCAE Grade 4 Superficial soft tissue fibrosis 10065798 C146140 Grade 4 Superficial soft tissue fibrosis Grade 4 Superficial soft tissue fibrosis Generalized; associated with signs or symptoms of impaired breathing or feeding NCI Generalized; associated with signs or symptoms of impaired breathing or feeding CTCAE_v5 Grade 4 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Grade 4 Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C146141 Life-threatening consequences; urgent multi-modality intervention indicated (e.g., lysis, thrombectomy, surgery) Life-threatening consequences; urgent multi-modality intervention indicated (e.g., lysis, thrombectomy, surgery) Grade 4 Superior Vena Cava Syndrome, CTCAE Grade 4 Superior vena cava syndrome 10042569 C146141 Grade 4 Superior vena cava syndrome Grade 4 Superior vena cava syndrome Life-threatening consequences; urgent multi-modality intervention indicated (e.g., lysis, thrombectomy, surgery) NCI Life-threatening consequences; urgent multi-modality intervention indicated (e.g., lysis, thrombectomy, surgery) CTCAE_v5 Grade 4 Superior Vena Cava Syndrome, CTCAE PT NCI Grade 4 Superior vena cava syndrome PT CTCAE_v5 ctcae5:C146142 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Surgical and Medical Procedures - Other, Specify, CTCAE Grade 4 Surgical and medical procedures - Other, specify 10042613 C146142 Grade 4 Surgical and medical procedures - Other, specify Grade 4 Surgical and medical procedures - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Grade 4 Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C146143 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Testicular Disorder, CTCAE Grade 4 Testicular disorder 10043306 C146143 Grade 4 Testicular disorder Grade 4 Testicular disorder Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Testicular Disorder, CTCAE PT NCI Grade 4 Testicular disorder PT CTCAE_v5 ctcae5:C146145 Life-threatening consequences with hemodynamic or neurologic instability Life-threatening consequences with hemodynamic or neurologic instability Grade 4 Thromboembolic Event, CTCAE Grade 4 Thromboembolic event 10043565 C146145 Grade 4 Thromboembolic event Grade 4 Thromboembolic event Life-threatening consequences with hemodynamic or neurologic instability NCI Life-threatening consequences with hemodynamic or neurologic instability CTCAE_v5 Grade 4 Thromboembolic Event, CTCAE PT NCI Grade 4 Thromboembolic event PT CTCAE_v5 ctcae5:C146146 Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) Grade 4 Thrombotic Thrombocytopenic Purpura, CTCAE Grade 4 Thrombotic thrombocytopenic purpura 10043648 C146146 Grade 4 Thrombotic thrombocytopenic purpura Grade 4 Thrombotic thrombocytopenic purpura Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) NCI Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure) CTCAE_v5 Grade 4 Thrombotic Thrombocytopenic Purpura, CTCAE PT NCI Grade 4 Thrombotic thrombocytopenic purpura PT CTCAE_v5 ctcae5:C146147 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tooth Infection, CTCAE Grade 4 Tooth infection 10048762 C146147 Grade 4 Tooth infection Grade 4 Tooth infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tooth Infection, CTCAE PT NCI Grade 4 Tooth infection PT CTCAE_v5 ctcae5:C146148 Skin sloughing covering >=30% BSA with associated symptoms (e.g., erythema, purpura, or epidermal detachment) Skin sloughing covering >=30% BSA with associated symptoms (e.g., erythema, purpura, or epidermal detachment) Grade 4 Toxic Epidermal Necrolysis, CTCAE Grade 4 Toxic epidermal necrolysis 10044223 C146148 Grade 4 Toxic epidermal necrolysis Grade 4 Toxic epidermal necrolysis Skin sloughing covering >=30% BSA with associated symptoms (e.g., erythema, purpura, or epidermal detachment) NCI Skin sloughing covering >=30% BSA with associated symptoms (e.g., erythema, purpura, or epidermal detachment) CTCAE_v5 Grade 4 Toxic Epidermal Necrolysis, CTCAE PT NCI Grade 4 Toxic epidermal necrolysis PT CTCAE_v5 ctcae5:C146151 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tracheal Mucositis, CTCAE Grade 4 Tracheal mucositis 10065900 C146151 Grade 4 Tracheal mucositis Grade 4 Tracheal mucositis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tracheal Mucositis, CTCAE PT NCI Grade 4 Tracheal mucositis PT CTCAE_v5 ctcae5:C146152 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Tracheal Obstruction, CTCAE Grade 4 Tracheal obstruction 10044291 C146152 Grade 4 Tracheal obstruction Grade 4 Tracheal obstruction Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Tracheal Obstruction, CTCAE PT NCI Grade 4 Tracheal obstruction PT CTCAE_v5 ctcae5:C146153 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Tracheal Stenosis, CTCAE Grade 4 Tracheal stenosis 10050816 C146153 Grade 4 Tracheal stenosis Grade 4 Tracheal stenosis Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Tracheal Stenosis, CTCAE PT NCI Grade 4 Tracheal stenosis PT CTCAE_v5 ctcae5:C146154 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tracheitis Grade 4 Tracheitis, CTCAE 10044302 C146154 Grade 4 Tracheitis Grade 4 Tracheitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tracheitis PT CTCAE_v5 Grade 4 Tracheitis, CTCAE PT NCI ctcae5:C146155 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tracheostomy Site Bleeding, CTCAE Grade 4 Tracheostomy site bleeding 10065749 C146155 Grade 4 Tracheostomy site bleeding Grade 4 Tracheostomy site bleeding Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tracheostomy Site Bleeding, CTCAE PT NCI Grade 4 Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C146156 Acute life-threatening secondary malignancy; blast crisis in leukemia Acute life-threatening secondary malignancy; blast crisis in leukemia Grade 4 Treatment Related Secondary Malignancy, CTCAE Grade 4 Treatment related secondary malignancy 10049737 C146156 Grade 4 Treatment related secondary malignancy Grade 4 Treatment related secondary malignancy Acute life-threatening secondary malignancy; blast crisis in leukemia NCI Acute life-threatening secondary malignancy; blast crisis in leukemia CTCAE_v5 Grade 4 Treatment Related Secondary Malignancy, CTCAE PT NCI Grade 4 Treatment related secondary malignancy PT CTCAE_v5 ctcae5:C146157 Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) Grade 4 Tricuspid Valve Disease, CTCAE Grade 4 Tricuspid valve disease 10061389 C146157 Grade 4 Tricuspid valve disease Grade 4 Tricuspid valve disease Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) NCI Life-threatening consequences; urgent intervention indicated (e.g., valve replacement, valvuloplasty) CTCAE_v5 Grade 4 Tricuspid Valve Disease, CTCAE PT NCI Grade 4 Tricuspid valve disease PT CTCAE_v5 ctcae5:C146158 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tumor Hemorrhage, CTCAE Grade 4 Tumor hemorrhage 10055351 C146158 Grade 4 Tumor hemorrhage Grade 4 Tumor hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tumor Hemorrhage, CTCAE PT NCI Grade 4 Tumor hemorrhage PT CTCAE_v5 ctcae5:C146159 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tumor Lysis Syndrome, CTCAE Grade 4 Tumor lysis syndrome 10045152 C146159 Grade 4 Tumor lysis syndrome Grade 4 Tumor lysis syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tumor Lysis Syndrome, CTCAE PT NCI Grade 4 Tumor lysis syndrome PT CTCAE_v5 ctcae5:C146160 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Upper Gastrointestinal Hemorrhage, CTCAE Grade 4 Upper gastrointestinal hemorrhage 10055356 C146160 Grade 4 Upper gastrointestinal hemorrhage Grade 4 Upper gastrointestinal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 4 Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C146161 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Upper Respiratory Infection, CTCAE Grade 4 Upper respiratory infection 10046300 C146161 Grade 4 Upper respiratory infection Grade 4 Upper respiratory infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Upper Respiratory Infection, CTCAE PT NCI Grade 4 Upper respiratory infection PT CTCAE_v5 ctcae5:C146162 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ureteric Anastomotic Leak, CTCAE Grade 4 Ureteric anastomotic leak 10065814 C146162 Grade 4 Ureteric anastomotic leak Grade 4 Ureteric anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ureteric Anastomotic Leak, CTCAE PT NCI Grade 4 Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C146163 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Urethral Anastomotic Leak, CTCAE Grade 4 Urethral anastomotic leak 10065815 C146163 Grade 4 Urethral anastomotic leak Grade 4 Urethral anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Urethral Anastomotic Leak, CTCAE PT NCI Grade 4 Urethral anastomotic leak PT CTCAE_v5 ctcae5:C146164 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Urethral Infection, CTCAE Grade 4 Urethral infection 10052298 C146164 Grade 4 Urethral infection Grade 4 Urethral infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Urethral Infection, CTCAE PT NCI Grade 4 Urethral infection PT CTCAE_v5 ctcae5:C146165 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Urinary Fistula, CTCAE Grade 4 Urinary fistula 10065368 C146165 Grade 4 Urinary fistula Grade 4 Urinary fistula Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Urinary Fistula, CTCAE PT NCI Grade 4 Urinary fistula PT CTCAE_v5 ctcae5:C146166 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Urinary Tract Infection, CTCAE Grade 4 Urinary tract infection 10046571 C146166 Grade 4 Urinary tract infection Grade 4 Urinary tract infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Urinary Tract Infection, CTCAE PT NCI Grade 4 Urinary tract infection PT CTCAE_v5 ctcae5:C146167 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Urinary Tract Obstruction, CTCAE Grade 4 Urinary tract obstruction 10061574 C146167 Grade 4 Urinary tract obstruction Grade 4 Urinary tract obstruction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Urinary Tract Obstruction, CTCAE PT NCI Grade 4 Urinary tract obstruction PT CTCAE_v5 ctcae5:C146168 Adult: Anuria (<240 ml in 24 hr); Pediatric: No urine output over 12 hours Adult: Anuria (<240 ml in 24 hr); Pediatric: No urine output over 12 hours Grade 4 Urine Output Decreased, CTCAE Grade 4 Urine output decreased 10059895 C146168 Grade 4 Urine output decreased Grade 4 Urine output decreased Adult: Anuria (<240 ml in 24 hr); Pediatric: No urine output over 12 hours NCI Adult: Anuria (<240 ml in 24 hr); Pediatric: No urine output over 12 hours CTCAE_v5 Grade 4 Urine Output Decreased, CTCAE PT NCI Grade 4 Urine output decreased PT CTCAE_v5 ctcae5:C146169 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Urostomy Leak, CTCAE Grade 4 Urostomy leak 10065882 C146169 Grade 4 Urostomy leak Grade 4 Urostomy leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Urostomy Leak, CTCAE PT NCI Grade 4 Urostomy leak PT CTCAE_v5 ctcae5:C146170 Life-threatening consequences; organ failure; urgent operative intervention indicated Life-threatening consequences; organ failure; urgent operative intervention indicated Grade 4 Urostomy Obstruction, CTCAE Grade 4 Urostomy obstruction 10065883 C146170 Grade 4 Urostomy obstruction Grade 4 Urostomy obstruction Life-threatening consequences; organ failure; urgent operative intervention indicated NCI Life-threatening consequences; organ failure; urgent operative intervention indicated CTCAE_v5 Grade 4 Urostomy Obstruction, CTCAE PT NCI Grade 4 Urostomy obstruction PT CTCAE_v5 ctcae5:C146171 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Urostomy Site Bleeding, CTCAE Grade 4 Urostomy site bleeding 10065748 C146171 Grade 4 Urostomy site bleeding Grade 4 Urostomy site bleeding Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Urostomy Site Bleeding, CTCAE PT NCI Grade 4 Urostomy site bleeding PT CTCAE_v5 ctcae5:C146172 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Urostomy Stenosis, CTCAE Grade 4 Urostomy stenosis 10065885 C146172 Grade 4 Urostomy stenosis Grade 4 Urostomy stenosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Urostomy Stenosis, CTCAE PT NCI Grade 4 Urostomy stenosis PT CTCAE_v5 ctcae5:C146173 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Uterine Anastomotic Leak, CTCAE Grade 4 Uterine anastomotic leak 10065886 C146173 Grade 4 Uterine anastomotic leak Grade 4 Uterine anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Uterine Anastomotic Leak, CTCAE PT NCI Grade 4 Uterine anastomotic leak PT CTCAE_v5 ctcae5:C146174 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Uterine Fistula, CTCAE Grade 4 Uterine fistula 10065811 C146174 Grade 4 Uterine fistula Grade 4 Uterine fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Uterine Fistula, CTCAE PT NCI Grade 4 Uterine fistula PT CTCAE_v5 ctcae5:C146176 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Uterine Infection, CTCAE Grade 4 Uterine infection 10062233 C146176 Grade 4 Uterine infection Grade 4 Uterine infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Uterine Infection, CTCAE PT NCI Grade 4 Uterine infection PT CTCAE_v5 ctcae5:C146177 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Uterine Perforation, CTCAE Grade 4 Uterine perforation 10046810 C146177 Grade 4 Uterine perforation Grade 4 Uterine perforation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Uterine Perforation, CTCAE PT NCI Grade 4 Uterine perforation PT CTCAE_v5 ctcae5:C146178 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vaccination Complication, CTCAE Grade 4 Vaccination complication 10046861 C146178 Grade 4 Vaccination complication Grade 4 Vaccination complication Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vaccination Complication, CTCAE PT NCI Grade 4 Vaccination complication PT CTCAE_v5 ctcae5:C146179 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Vaginal Anastomotic Leak, CTCAE Grade 4 Vaginal anastomotic leak 10065887 C146179 Grade 4 Vaginal anastomotic leak Grade 4 Vaginal anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Vaginal Anastomotic Leak, CTCAE PT NCI Grade 4 Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C146182 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vaginal Infection, CTCAE Grade 4 Vaginal infection 10046914 C146182 Grade 4 Vaginal infection Grade 4 Vaginal infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vaginal Infection, CTCAE PT NCI Grade 4 Vaginal infection PT CTCAE_v5 ctcae5:C146183 Life-threatening consequences; widespread areas of mucosal ulceration; urgent intervention indicated Life-threatening consequences; widespread areas of mucosal ulceration; urgent intervention indicated Grade 4 Vaginal Inflammation, CTCAE Grade 4 Vaginal inflammation 10046916 C146183 Grade 4 Vaginal inflammation Grade 4 Vaginal inflammation Life-threatening consequences; widespread areas of mucosal ulceration; urgent intervention indicated NCI Life-threatening consequences; widespread areas of mucosal ulceration; urgent intervention indicated CTCAE_v5 Grade 4 Vaginal Inflammation, CTCAE PT NCI Grade 4 Vaginal inflammation PT CTCAE_v5 ctcae5:C146184 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vaginal Perforation, CTCAE Grade 4 Vaginal perforation 10065818 C146184 Grade 4 Vaginal perforation Grade 4 Vaginal perforation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vaginal Perforation, CTCAE PT NCI Grade 4 Vaginal perforation PT CTCAE_v5 ctcae5:C146185 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vagus Nerve Disorder, CTCAE Grade 4 Vagus nerve disorder 10061403 C146185 Grade 4 Vagus nerve disorder Grade 4 Vagus nerve disorder Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vagus Nerve Disorder, CTCAE PT NCI Grade 4 Vagus nerve disorder PT CTCAE_v5 ctcae5:C146186 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Vas Deferens Anastomotic Leak, CTCAE Grade 4 Vas deferens anastomotic leak 10065888 C146186 Grade 4 Vas deferens anastomotic leak Grade 4 Vas deferens anastomotic leak Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Vas Deferens Anastomotic Leak, CTCAE PT NCI Grade 4 Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C146187 Life-threatening consequences with hemodynamic or neurologic instability Life-threatening consequences with hemodynamic or neurologic instability Grade 4 Vascular Access Complication, CTCAE Grade 4 Vascular access complication 10062169 C146187 Grade 4 Vascular access complication Grade 4 Vascular access complication Life-threatening consequences with hemodynamic or neurologic instability NCI Life-threatening consequences with hemodynamic or neurologic instability CTCAE_v5 Grade 4 Vascular Access Complication, CTCAE PT NCI Grade 4 Vascular access complication PT CTCAE_v5 ctcae5:C146188 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vascular Disorders - Other, Specify, CTCAE Grade 4 Vascular disorders - Other, specify 10047065 C146188 Grade 4 Vascular disorders - Other, specify Grade 4 Vascular disorders - Other, specify Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vascular Disorders - Other, Specify, CTCAE PT NCI Grade 4 Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C146189 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vasovagal Reaction, CTCAE Grade 4 Vasovagal reaction 10047166 C146189 Grade 4 Vasovagal reaction Grade 4 Vasovagal reaction Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vasovagal Reaction, CTCAE PT NCI Grade 4 Vasovagal reaction PT CTCAE_v5 ctcae5:C146190 Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Grade 4 Venous Injury, CTCAE Grade 4 Venous injury 10047228 C146190 Grade 4 Venous injury Grade 4 Venous injury Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated NCI Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated CTCAE_v5 Grade 4 Venous Injury, CTCAE PT NCI Grade 4 Venous injury PT CTCAE_v5 ctcae5:C146191 Life-threatening consequences; hemodynamic compromise Life-threatening consequences; hemodynamic compromise Grade 4 Ventricular Arrhythmia, CTCAE Grade 4 Ventricular arrhythmia 10047281 C146191 Grade 4 Ventricular arrhythmia Grade 4 Ventricular arrhythmia Life-threatening consequences; hemodynamic compromise NCI Life-threatening consequences; hemodynamic compromise CTCAE_v5 Grade 4 Ventricular Arrhythmia, CTCAE PT NCI Grade 4 Ventricular arrhythmia PT CTCAE_v5 ctcae5:C146192 Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated Grade 4 Visceral Arterial Ischemia, CTCAE Grade 4 Visceral arterial ischemia 10054692 C146192 Grade 4 Visceral arterial ischemia Grade 4 Visceral arterial ischemia Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated NCI Life-threatening consequences; evidence of end organ damage; urgent operative intervention indicated CTCAE_v5 Grade 4 Visceral Arterial Ischemia, CTCAE PT NCI Grade 4 Visceral arterial ischemia PT CTCAE_v5 ctcae5:C146193 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Vision Decreased, CTCAE Grade 4 Vision decreased 10047516 C146193 Grade 4 Vision decreased Grade 4 Vision decreased Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Vision Decreased, CTCAE PT NCI Grade 4 Vision decreased PT CTCAE_v5 ctcae5:C146194 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Vitreous Hemorrhage, CTCAE Grade 4 Vitreous hemorrhage 10047656 C146194 Grade 4 Vitreous hemorrhage Grade 4 Vitreous hemorrhage Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Vitreous Hemorrhage, CTCAE PT NCI Grade 4 Vitreous hemorrhage PT CTCAE_v5 ctcae5:C146195 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vulval Infection, CTCAE Grade 4 Vulval infection 10065772 C146195 Grade 4 Vulval infection Grade 4 Vulval infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vulval Infection, CTCAE PT NCI Grade 4 Vulval infection PT CTCAE_v5 ctcae5:C146196 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Watering Eyes, CTCAE Grade 4 Watering eyes 10047848 C146196 Grade 4 Watering eyes Grade 4 Watering eyes Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Watering Eyes, CTCAE PT NCI Grade 4 Watering eyes PT CTCAE_v5 ctcae5:C146197 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Wheezing Grade 4 Wheezing, CTCAE 10047924 C146197 Grade 4 Wheezing Grade 4 Wheezing Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Wheezing PT CTCAE_v5 Grade 4 Wheezing, CTCAE PT NCI ctcae5:C146198 <1000/mm3; <1.0 x 10e9/L <1000/mm3; <1.0 x 10e9/L Grade 4 White Blood Cell Decreased, CTCAE Grade 4 White blood cell decreased 10049182 C146198 Grade 4 White blood cell decreased Grade 4 White blood cell decreased <1000/mm3; <1.0 x 10e9/L NCI <1000/mm3; <1.0 x 10e9/L CTCAE_v5 Grade 4 White Blood Cell Decreased, CTCAE PT NCI Grade 4 White blood cell decreased PT CTCAE_v5 ctcae5:C146199 Life-threatening consequences Life-threatening consequences Grade 4 Wound Complication, CTCAE Grade 4 Wound complication 10053692 C146199 Grade 4 Wound complication Grade 4 Wound complication Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Wound Complication, CTCAE PT NCI Grade 4 Wound complication PT CTCAE_v5 ctcae5:C146200 Life-threatening consequences; symptomatic hernia with evidence of strangulation; fascial disruption with evisceration; major reconstruction flap, grafting, resection, or amputation indicated Life-threatening consequences; symptomatic hernia with evidence of strangulation; fascial disruption with evisceration; major reconstruction flap, grafting, resection, or amputation indicated Grade 4 Wound Dehiscence, CTCAE Grade 4 Wound dehiscence 10048031 C146200 Grade 4 Wound dehiscence Grade 4 Wound dehiscence Life-threatening consequences; symptomatic hernia with evidence of strangulation; fascial disruption with evisceration; major reconstruction flap, grafting, resection, or amputation indicated NCI Life-threatening consequences; symptomatic hernia with evidence of strangulation; fascial disruption with evisceration; major reconstruction flap, grafting, resection, or amputation indicated CTCAE_v5 Grade 4 Wound Dehiscence, CTCAE PT NCI Grade 4 Wound dehiscence PT CTCAE_v5 ctcae5:C146201 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Wound Infection, CTCAE Grade 4 Wound infection 10048038 C146201 Grade 4 Wound infection Grade 4 Wound infection Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Wound Infection, CTCAE PT NCI Grade 4 Wound infection PT CTCAE_v5 ctcae5:C146202 Death Death Grade 5 Abdominal Infection, CTCAE Grade 5 Abdominal infection 10056519 C146202 Grade 5 Abdominal infection Grade 5 Abdominal infection Death NCI Death CTCAE_v5 Grade 5 Abdominal Infection, CTCAE PT NCI Grade 5 Abdominal infection PT CTCAE_v5 ctcae5:C146203 Death Death Grade 5 Abdominal Soft Tissue Necrosis, CTCAE Grade 5 Abdominal soft tissue necrosis 10065775 C146203 Grade 5 Abdominal soft tissue necrosis Grade 5 Abdominal soft tissue necrosis Death NCI Death CTCAE_v5 Grade 5 Abdominal Soft Tissue Necrosis, CTCAE PT NCI Grade 5 Abdominal soft tissue necrosis PT CTCAE_v5 ctcae5:C146204 Death Death Grade 5 Acidosis Grade 5 Acidosis, CTCAE 10000486 C146204 Grade 5 Acidosis Grade 5 Acidosis Death NCI Death CTCAE_v5 Grade 5 Acidosis PT CTCAE_v5 Grade 5 Acidosis, CTCAE PT NCI ctcae5:C146205 Death Death Grade 5 Acute Kidney Injury, CTCAE Grade 5 Acute kidney injury 10069339 C146205 Grade 5 Acute kidney injury Grade 5 Acute kidney injury Death NCI Death CTCAE_v5 Grade 5 Acute Kidney Injury, CTCAE PT NCI Grade 5 Acute kidney injury PT CTCAE_v5 ctcae5:C146206 Death Death Grade 5 Alcohol Intolerance, CTCAE Grade 5 Alcohol intolerance 10001598 C146206 Grade 5 Alcohol intolerance Grade 5 Alcohol intolerance Death NCI Death CTCAE_v5 Grade 5 Alcohol Intolerance, CTCAE PT NCI Grade 5 Alcohol intolerance PT CTCAE_v5 ctcae5:C146207 Death Death Grade 5 Alkalosis Grade 5 Alkalosis, CTCAE 10001680 C146207 Grade 5 Alkalosis Grade 5 Alkalosis Death NCI Death CTCAE_v5 Grade 5 Alkalosis PT CTCAE_v5 Grade 5 Alkalosis, CTCAE PT NCI ctcae5:C146208 Death Death Grade 5 Allergic Reaction, CTCAE Grade 5 Allergic reaction 10001718 C146208 Grade 5 Allergic reaction Grade 5 Allergic reaction Death NCI Death CTCAE_v5 Grade 5 Allergic Reaction, CTCAE PT NCI Grade 5 Allergic reaction PT CTCAE_v5 ctcae5:C146209 Death Death Grade 5 Anal Fistula, CTCAE Grade 5 Anal fistula 10002156 C146209 Grade 5 Anal fistula Grade 5 Anal fistula Death NCI Death CTCAE_v5 Grade 5 Anal Fistula, CTCAE PT NCI Grade 5 Anal fistula PT CTCAE_v5 ctcae5:C146210 Death Death Grade 5 Anal Hemorrhage, CTCAE Grade 5 Anal hemorrhage 10055226 C146210 Grade 5 Anal hemorrhage Grade 5 Anal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Anal Hemorrhage, CTCAE PT NCI Grade 5 Anal hemorrhage PT CTCAE_v5 ctcae5:C146211 Death Death Grade 5 Anal Necrosis, CTCAE Grade 5 Anal necrosis 10065722 C146211 Grade 5 Anal necrosis Grade 5 Anal necrosis Death NCI Death CTCAE_v5 Grade 5 Anal Necrosis, CTCAE PT NCI Grade 5 Anal necrosis PT CTCAE_v5 ctcae5:C146212 Death Death Grade 5 Anal Stenosis, CTCAE Grade 5 Anal stenosis 10002176 C146212 Grade 5 Anal stenosis Grade 5 Anal stenosis Death NCI Death CTCAE_v5 Grade 5 Anal Stenosis, CTCAE PT NCI Grade 5 Anal stenosis PT CTCAE_v5 ctcae5:C146213 Death Death Grade 5 Anal Ulcer, CTCAE Grade 5 Anal ulcer 10002180 C146213 Grade 5 Anal ulcer Grade 5 Anal ulcer Death NCI Death CTCAE_v5 Grade 5 Anal Ulcer, CTCAE PT NCI Grade 5 Anal ulcer PT CTCAE_v5 ctcae5:C146214 Death Death Grade 5 Anaphylaxis Grade 5 Anaphylaxis, CTCAE 10002218 C146214 Grade 5 Anaphylaxis Grade 5 Anaphylaxis Death NCI Death CTCAE_v5 Grade 5 Anaphylaxis PT CTCAE_v5 Grade 5 Anaphylaxis, CTCAE PT NCI ctcae5:C146215 Death Death Grade 5 Anemia Grade 5 Anemia, CTCAE 10002272 C146215 Grade 5 Anemia Grade 5 Anemia Death NCI Death CTCAE_v5 Grade 5 Anemia PT CTCAE_v5 Grade 5 Anemia, CTCAE PT NCI ctcae5:C146216 Death Death Grade 5 Anorectal Infection, CTCAE Grade 5 Anorectal infection 10061640 C146216 Grade 5 Anorectal infection Grade 5 Anorectal infection Death NCI Death CTCAE_v5 Grade 5 Anorectal Infection, CTCAE PT NCI Grade 5 Anorectal infection PT CTCAE_v5 ctcae5:C146217 Death Death Grade 5 Aortic Injury, CTCAE Grade 5 Aortic injury 10002899 C146217 Grade 5 Aortic injury Grade 5 Aortic injury Death NCI Death CTCAE_v5 Grade 5 Aortic Injury, CTCAE PT NCI Grade 5 Aortic injury PT CTCAE_v5 ctcae5:C146218 Death Death Grade 5 Aortic Valve Disease, CTCAE Grade 5 Aortic valve disease 10061589 C146218 Grade 5 Aortic valve disease Grade 5 Aortic valve disease Death NCI Death CTCAE_v5 Grade 5 Aortic Valve Disease, CTCAE PT NCI Grade 5 Aortic valve disease PT CTCAE_v5 ctcae5:C146219 Death Death Grade 5 Appendicitis Perforated, CTCAE Grade 5 Appendicitis perforated 10003012 C146219 Grade 5 Appendicitis perforated Grade 5 Appendicitis perforated Death NCI Death CTCAE_v5 Grade 5 Appendicitis Perforated, CTCAE PT NCI Grade 5 Appendicitis perforated PT CTCAE_v5 ctcae5:C146220 Death Death Grade 5 Appendicitis Grade 5 Appendicitis, CTCAE 10003011 C146220 Grade 5 Appendicitis Grade 5 Appendicitis Death NCI Death CTCAE_v5 Grade 5 Appendicitis PT CTCAE_v5 Grade 5 Appendicitis, CTCAE PT NCI ctcae5:C146221 Death Death Grade 5 Arachnoiditis Grade 5 Arachnoiditis, CTCAE 10003074 C146221 Grade 5 Arachnoiditis Grade 5 Arachnoiditis Death NCI Death CTCAE_v5 Grade 5 Arachnoiditis PT CTCAE_v5 Grade 5 Arachnoiditis, CTCAE PT NCI ctcae5:C146222 Death Death Grade 5 Arterial Injury, CTCAE Grade 5 Arterial injury 10003162 C146222 Grade 5 Arterial injury Grade 5 Arterial injury Death NCI Death CTCAE_v5 Grade 5 Arterial Injury, CTCAE PT NCI Grade 5 Arterial injury PT CTCAE_v5 ctcae5:C146223 Death Death Grade 5 Arterial Thromboembolism, CTCAE Grade 5 Arterial thromboembolism 10073529 C146223 Grade 5 Arterial thromboembolism Grade 5 Arterial thromboembolism Death NCI Death CTCAE_v5 Grade 5 Arterial Thromboembolism, CTCAE PT NCI Grade 5 Arterial thromboembolism PT CTCAE_v5 ctcae5:C146224 Death Death Grade 5 Arteritis Infective, CTCAE Grade 5 Arteritis infective 10065744 C146224 Grade 5 Arteritis infective Grade 5 Arteritis infective Death NCI Death CTCAE_v5 Grade 5 Arteritis Infective, CTCAE PT NCI Grade 5 Arteritis infective PT CTCAE_v5 ctcae5:C146225 Death Death Grade 5 Ascites Grade 5 Ascites, CTCAE 10003445 C146225 Grade 5 Ascites Grade 5 Ascites Death NCI Death CTCAE_v5 Grade 5 Ascites PT CTCAE_v5 Grade 5 Ascites, CTCAE PT NCI ctcae5:C146226 Death Death Grade 5 Atrioventricular Block Complete, CTCAE Grade 5 Atrioventricular block complete 10003673 C146226 Grade 5 Atrioventricular block complete Grade 5 Atrioventricular block complete Death NCI Death CTCAE_v5 Grade 5 Atrioventricular Block Complete, CTCAE PT NCI Grade 5 Atrioventricular block complete PT CTCAE_v5 ctcae5:C146227 Death Death Grade 5 Autoimmune Disorder, CTCAE Grade 5 Autoimmune disorder 10061664 C146227 Grade 5 Autoimmune disorder Grade 5 Autoimmune disorder Death NCI Death CTCAE_v5 Grade 5 Autoimmune Disorder, CTCAE PT NCI Grade 5 Autoimmune disorder PT CTCAE_v5 ctcae5:C146228 Death Death Grade 5 Avascular Necrosis, CTCAE Grade 5 Avascular necrosis 10066480 C146228 Grade 5 Avascular necrosis Grade 5 Avascular necrosis Death NCI Death CTCAE_v5 Grade 5 Avascular Necrosis, CTCAE PT NCI Grade 5 Avascular necrosis PT CTCAE_v5 ctcae5:C146229 Death Death Grade 5 Bile Duct Stenosis, CTCAE Grade 5 Bile duct stenosis 10051341 C146229 Grade 5 Bile duct stenosis Grade 5 Bile duct stenosis Death NCI Death CTCAE_v5 Grade 5 Bile Duct Stenosis, CTCAE PT NCI Grade 5 Bile duct stenosis PT CTCAE_v5 ctcae5:C146230 Death Death Grade 5 Biliary Anastomotic Leak, CTCAE Grade 5 Biliary anastomotic leak 10050458 C146230 Grade 5 Biliary anastomotic leak Grade 5 Biliary anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Biliary Anastomotic Leak, CTCAE PT NCI Grade 5 Biliary anastomotic leak PT CTCAE_v5 ctcae5:C146231 Death Death Grade 5 Biliary Fistula, CTCAE Grade 5 Biliary fistula 10004665 C146231 Grade 5 Biliary fistula Grade 5 Biliary fistula Death NCI Death CTCAE_v5 Grade 5 Biliary Fistula, CTCAE PT NCI Grade 5 Biliary fistula PT CTCAE_v5 ctcae5:C146232 Death Death Grade 5 Biliary Tract Infection, CTCAE Grade 5 Biliary tract infection 10061695 C146232 Grade 5 Biliary tract infection Grade 5 Biliary tract infection Death NCI Death CTCAE_v5 Grade 5 Biliary Tract Infection, CTCAE PT NCI Grade 5 Biliary tract infection PT CTCAE_v5 ctcae5:C146233 Death Death Grade 5 Bladder Anastomotic Leak, CTCAE Grade 5 Bladder anastomotic leak 10065802 C146233 Grade 5 Bladder anastomotic leak Grade 5 Bladder anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Bladder Anastomotic Leak, CTCAE PT NCI Grade 5 Bladder anastomotic leak PT CTCAE_v5 ctcae5:C146234 Death Death Grade 5 Bladder Infection, CTCAE Grade 5 Bladder infection 10005047 C146234 Grade 5 Bladder infection Grade 5 Bladder infection Death NCI Death CTCAE_v5 Grade 5 Bladder Infection, CTCAE PT NCI Grade 5 Bladder infection PT CTCAE_v5 ctcae5:C146235 Death Death Grade 5 Blood and Lymphatic System Disorders - Other, Specify, CTCAE Grade 5 Blood and lymphatic system disorders - Other, specify 10005329 C146235 Grade 5 Blood and lymphatic system disorders - Other, specify Grade 5 Blood and lymphatic system disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Blood and Lymphatic System Disorders - Other, Specify, CTCAE PT NCI Grade 5 Blood and lymphatic system disorders - Other, specify PT CTCAE_v5 ctcae5:C146236 Death Death Grade 5 Bone Infection, CTCAE Grade 5 Bone infection 10061017 C146236 Grade 5 Bone infection Grade 5 Bone infection Death NCI Death CTCAE_v5 Grade 5 Bone Infection, CTCAE PT NCI Grade 5 Bone infection PT CTCAE_v5 ctcae5:C146237 Death Death Grade 5 Bone Marrow Hypocellular, CTCAE Grade 5 Bone marrow hypocellular 10048580 C146237 Grade 5 Bone marrow hypocellular Grade 5 Bone marrow hypocellular Death NCI Death CTCAE_v5 Grade 5 Bone Marrow Hypocellular, CTCAE PT NCI Grade 5 Bone marrow hypocellular PT CTCAE_v5 ctcae5:C146238 Death Death Grade 5 Breast Infection, CTCAE Grade 5 Breast infection 10006259 C146238 Grade 5 Breast infection Grade 5 Breast infection Death NCI Death CTCAE_v5 Grade 5 Breast Infection, CTCAE PT NCI Grade 5 Breast infection PT CTCAE_v5 ctcae5:C146239 Death Death Grade 5 Bronchial Fistula, CTCAE Grade 5 Bronchial fistula 10006437 C146239 Grade 5 Bronchial fistula Grade 5 Bronchial fistula Death NCI Death CTCAE_v5 Grade 5 Bronchial Fistula, CTCAE PT NCI Grade 5 Bronchial fistula PT CTCAE_v5 ctcae5:C146240 Death Death Grade 5 Bronchial Infection, CTCAE Grade 5 Bronchial infection 10055078 C146240 Grade 5 Bronchial infection Grade 5 Bronchial infection Death NCI Death CTCAE_v5 Grade 5 Bronchial Infection, CTCAE PT NCI Grade 5 Bronchial infection PT CTCAE_v5 ctcae5:C146241 Death Death Grade 5 Bronchial Obstruction, CTCAE Grade 5 Bronchial obstruction 10006440 C146241 Grade 5 Bronchial obstruction Grade 5 Bronchial obstruction Death NCI Death CTCAE_v5 Grade 5 Bronchial Obstruction, CTCAE PT NCI Grade 5 Bronchial obstruction PT CTCAE_v5 ctcae5:C146242 Death Death Grade 5 Bronchial Stricture, CTCAE Grade 5 Bronchial stricture 10063524 C146242 Grade 5 Bronchial stricture Grade 5 Bronchial stricture Death NCI Death CTCAE_v5 Grade 5 Bronchial Stricture, CTCAE PT NCI Grade 5 Bronchial stricture PT CTCAE_v5 ctcae5:C146243 Death Death Grade 5 Bronchopleural Fistula, CTCAE Grade 5 Bronchopleural fistula 10053481 C146243 Grade 5 Bronchopleural fistula Grade 5 Bronchopleural fistula Death NCI Death CTCAE_v5 Grade 5 Bronchopleural Fistula, CTCAE PT NCI Grade 5 Bronchopleural fistula PT CTCAE_v5 ctcae5:C146244 Death Death Grade 5 Bronchopulmonary Hemorrhage, CTCAE Grade 5 Bronchopulmonary hemorrhage 10065746 C146244 Grade 5 Bronchopulmonary hemorrhage Grade 5 Bronchopulmonary hemorrhage Death NCI Death CTCAE_v5 Grade 5 Bronchopulmonary Hemorrhage, CTCAE PT NCI Grade 5 Bronchopulmonary hemorrhage PT CTCAE_v5 ctcae5:C146245 Death Death Grade 5 Bronchospasm Grade 5 Bronchospasm, CTCAE 10006482 C146245 Grade 5 Bronchospasm Grade 5 Bronchospasm Death NCI Death CTCAE_v5 Grade 5 Bronchospasm PT CTCAE_v5 Grade 5 Bronchospasm, CTCAE PT NCI ctcae5:C146246 Death Death Grade 5 Budd-Chiari Syndrome, CTCAE Grade 5 Budd-Chiari syndrome 10006537 C146246 Grade 5 Budd-Chiari syndrome Grade 5 Budd-Chiari syndrome Death NCI Death CTCAE_v5 Grade 5 Budd-Chiari Syndrome, CTCAE PT NCI Grade 5 Budd-Chiari syndrome PT CTCAE_v5 ctcae5:C146247 Death Death Grade 5 Bullous Dermatitis, CTCAE Grade 5 Bullous dermatitis 10006556 C146247 Grade 5 Bullous dermatitis Grade 5 Bullous dermatitis Death NCI Death CTCAE_v5 Grade 5 Bullous Dermatitis, CTCAE PT NCI Grade 5 Bullous dermatitis PT CTCAE_v5 ctcae5:C146248 Death Death Grade 5 Capillary Leak Syndrome, CTCAE Grade 5 Capillary leak syndrome 10007196 C146248 Grade 5 Capillary leak syndrome Grade 5 Capillary leak syndrome Death NCI Death CTCAE_v5 Grade 5 Capillary Leak Syndrome, CTCAE PT NCI Grade 5 Capillary leak syndrome PT CTCAE_v5 ctcae5:C146249 Death Death Grade 5 Cardiac Arrest, CTCAE Grade 5 Cardiac arrest 10007515 C146249 Grade 5 Cardiac arrest Grade 5 Cardiac arrest Death NCI Death CTCAE_v5 Grade 5 Cardiac Arrest, CTCAE PT NCI Grade 5 Cardiac arrest PT CTCAE_v5 ctcae5:C146250 Death Death Grade 5 Cardiac Disorders - Other, Specify, CTCAE Grade 5 Cardiac disorders - Other, specify 10007541 C146250 Grade 5 Cardiac disorders - Other, specify Grade 5 Cardiac disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Cardiac Disorders - Other, Specify, CTCAE PT NCI Grade 5 Cardiac disorders - Other, specify PT CTCAE_v5 ctcae5:C146251 Death Death Grade 5 Catheter Related Infection, CTCAE Grade 5 Catheter related infection 10007810 C146251 Grade 5 Catheter related infection Grade 5 Catheter related infection Death NCI Death CTCAE_v5 Grade 5 Catheter Related Infection, CTCAE PT NCI Grade 5 Catheter related infection PT CTCAE_v5 ctcae5:C146252 Death Death Grade 5 Cecal Hemorrhage, CTCAE Grade 5 Cecal hemorrhage 10065747 C146252 Grade 5 Cecal hemorrhage Grade 5 Cecal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Cecal Hemorrhage, CTCAE PT NCI Grade 5 Cecal hemorrhage PT CTCAE_v5 ctcae5:C146253 Death Death Grade 5 Cecal Infection, CTCAE Grade 5 Cecal infection 10065761 C146253 Grade 5 Cecal infection Grade 5 Cecal infection Death NCI Death CTCAE_v5 Grade 5 Cecal Infection, CTCAE PT NCI Grade 5 Cecal infection PT CTCAE_v5 ctcae5:C146254 Death Death Grade 5 Central Nervous System Necrosis, CTCAE Grade 5 Central nervous system necrosis 10065784 C146254 Grade 5 Central nervous system necrosis Grade 5 Central nervous system necrosis Death NCI Death CTCAE_v5 Grade 5 Central Nervous System Necrosis, CTCAE PT NCI Grade 5 Central nervous system necrosis PT CTCAE_v5 ctcae5:C146255 Death Death Grade 5 Cerebrospinal Fluid Leakage, CTCAE Grade 5 Cerebrospinal fluid leakage 10008164 C146255 Grade 5 Cerebrospinal fluid leakage Grade 5 Cerebrospinal fluid leakage Death NCI Death CTCAE_v5 Grade 5 Cerebrospinal Fluid Leakage, CTCAE PT NCI Grade 5 Cerebrospinal fluid leakage PT CTCAE_v5 ctcae5:C146256 Death Death Grade 5 Cervicitis Infection, CTCAE Grade 5 Cervicitis infection 10008330 C146256 Grade 5 Cervicitis infection Grade 5 Cervicitis infection Death NCI Death CTCAE_v5 Grade 5 Cervicitis Infection, CTCAE PT NCI Grade 5 Cervicitis infection PT CTCAE_v5 ctcae5:C146257 Death Death Grade 5 Chest Wall Necrosis, CTCAE Grade 5 Chest wall necrosis 10048831 C146257 Grade 5 Chest wall necrosis Grade 5 Chest wall necrosis Death NCI Death CTCAE_v5 Grade 5 Chest Wall Necrosis, CTCAE PT NCI Grade 5 Chest wall necrosis PT CTCAE_v5 ctcae5:C146258 Death Death Grade 5 Chronic Kidney Disease, CTCAE Grade 5 Chronic kidney disease 10064848 C146258 Grade 5 Chronic kidney disease Grade 5 Chronic kidney disease Death NCI Death CTCAE_v5 Grade 5 Chronic Kidney Disease, CTCAE PT NCI Grade 5 Chronic kidney disease PT CTCAE_v5 ctcae5:C146259 Death Death Grade 5 Chylous Ascites, CTCAE Grade 5 Chylous ascites 10009167 C146259 Grade 5 Chylous ascites Grade 5 Chylous ascites Death NCI Death CTCAE_v5 Grade 5 Chylous Ascites, CTCAE PT NCI Grade 5 Chylous ascites PT CTCAE_v5 ctcae5:C146260 Death Death Grade 5 Colonic Fistula, CTCAE Grade 5 Colonic fistula 10009995 C146260 Grade 5 Colonic fistula Grade 5 Colonic fistula Death NCI Death CTCAE_v5 Grade 5 Colonic Fistula, CTCAE PT NCI Grade 5 Colonic fistula PT CTCAE_v5 ctcae5:C146261 Death Death Grade 5 Colonic Hemorrhage, CTCAE Grade 5 Colonic hemorrhage 10009998 C146261 Grade 5 Colonic hemorrhage Grade 5 Colonic hemorrhage Death NCI Death CTCAE_v5 Grade 5 Colonic Hemorrhage, CTCAE PT NCI Grade 5 Colonic hemorrhage PT CTCAE_v5 ctcae5:C146262 Death Death Grade 5 Colonic Obstruction, CTCAE Grade 5 Colonic obstruction 10010000 C146262 Grade 5 Colonic obstruction Grade 5 Colonic obstruction Death NCI Death CTCAE_v5 Grade 5 Colonic Obstruction, CTCAE PT NCI Grade 5 Colonic obstruction PT CTCAE_v5 ctcae5:C146263 Death Death Grade 5 Colonic Perforation, CTCAE Grade 5 Colonic perforation 10010001 C146263 Grade 5 Colonic perforation Grade 5 Colonic perforation Death NCI Death CTCAE_v5 Grade 5 Colonic Perforation, CTCAE PT NCI Grade 5 Colonic perforation PT CTCAE_v5 ctcae5:C146264 Death Death Grade 5 Colonic Stenosis, CTCAE Grade 5 Colonic stenosis 10010004 C146264 Grade 5 Colonic stenosis Grade 5 Colonic stenosis Death NCI Death CTCAE_v5 Grade 5 Colonic Stenosis, CTCAE PT NCI Grade 5 Colonic stenosis PT CTCAE_v5 ctcae5:C146265 Death Death Grade 5 Colonic Ulcer, CTCAE Grade 5 Colonic ulcer 10010006 C146265 Grade 5 Colonic ulcer Grade 5 Colonic ulcer Death NCI Death CTCAE_v5 Grade 5 Colonic Ulcer, CTCAE PT NCI Grade 5 Colonic ulcer PT CTCAE_v5 ctcae5:C146266 Death Death Grade 5 Conduction Disorder, CTCAE Grade 5 Conduction disorder 10010276 C146266 Grade 5 Conduction disorder Grade 5 Conduction disorder Death NCI Death CTCAE_v5 Grade 5 Conduction Disorder, CTCAE PT NCI Grade 5 Conduction disorder PT CTCAE_v5 ctcae5:C146267 Death Death Grade 5 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE Grade 5 Congenital, familial and genetic disorders - Other, specify 10010331 C146267 Grade 5 Congenital, familial and genetic disorders - Other, specify Grade 5 Congenital, familial and genetic disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Congenital, Familial and Genetic Disorders - Other, Specify, CTCAE PT NCI Grade 5 Congenital, familial and genetic disorders - Other, specify PT CTCAE_v5 ctcae5:C146268 Death Death Grade 5 Corneal Infection, CTCAE Grade 5 Corneal infection 10061788 C146268 Grade 5 Corneal infection Grade 5 Corneal infection Death NCI Death CTCAE_v5 Grade 5 Corneal Infection, CTCAE PT NCI Grade 5 Corneal infection PT CTCAE_v5 ctcae5:C146269 Death Death Grade 5 Cranial Nerve Infection, CTCAE Grade 5 Cranial nerve infection 10065765 C146269 Grade 5 Cranial nerve infection Grade 5 Cranial nerve infection Death NCI Death CTCAE_v5 Grade 5 Cranial Nerve Infection, CTCAE PT NCI Grade 5 Cranial nerve infection PT CTCAE_v5 ctcae5:C146270 Death Death Grade 5 Cystitis Noninfective, CTCAE Grade 5 Cystitis noninfective 10063057 C146270 Grade 5 Cystitis noninfective Grade 5 Cystitis noninfective Death NCI Death CTCAE_v5 Grade 5 Cystitis Noninfective, CTCAE PT NCI Grade 5 Cystitis noninfective PT CTCAE_v5 ctcae5:C146271 Death Death Grade 5 Cytokine Release Syndrome, CTCAE Grade 5 Cytokine release syndrome 10052015 C146271 Grade 5 Cytokine release syndrome Grade 5 Cytokine release syndrome Death NCI Death CTCAE_v5 Grade 5 Cytokine Release Syndrome, CTCAE PT NCI Grade 5 Cytokine release syndrome PT CTCAE_v5 ctcae5:C146272 Death Death Grade 5 Cytomegalovirus Infection Reactivation, CTCAE Grade 5 Cytomegalovirus infection reactivation 10058666 C146272 Grade 5 Cytomegalovirus infection reactivation Grade 5 Cytomegalovirus infection reactivation Death NCI Death CTCAE_v5 Grade 5 Cytomegalovirus Infection Reactivation, CTCAE PT NCI Grade 5 Cytomegalovirus infection reactivation PT CTCAE_v5 ctcae5:C146274 Death Death Grade 5 Delirium Grade 5 Delirium, CTCAE 10012218 C146274 Grade 5 Delirium Grade 5 Delirium Death NCI Death CTCAE_v5 Grade 5 Delirium PT CTCAE_v5 Grade 5 Delirium, CTCAE PT NCI ctcae5:C146275 Death Death Grade 5 Delusions Grade 5 Delusions, CTCAE 10012260 C146275 Grade 5 Delusions Grade 5 Delusions Death NCI Death CTCAE_v5 Grade 5 Delusions PT CTCAE_v5 Grade 5 Delusions, CTCAE PT NCI ctcae5:C146276 Death Death Grade 5 Depressed Level of Consciousness, CTCAE Grade 5 Depressed level of consciousness 10012373 C146276 Grade 5 Depressed level of consciousness Grade 5 Depressed level of consciousness Death NCI Death CTCAE_v5 Grade 5 Depressed Level of Consciousness, CTCAE PT NCI Grade 5 Depressed level of consciousness PT CTCAE_v5 ctcae5:C146277 Death Death Grade 5 Dermatitis Radiation, CTCAE Grade 5 Dermatitis radiation 10061103 C146277 Grade 5 Dermatitis radiation Grade 5 Dermatitis radiation Death NCI Death CTCAE_v5 Grade 5 Dermatitis Radiation, CTCAE PT NCI Grade 5 Dermatitis radiation PT CTCAE_v5 ctcae5:C146278 Death Death Grade 5 Device Related Infection, CTCAE Grade 5 Device related infection 10064687 C146278 Grade 5 Device related infection Grade 5 Device related infection Death NCI Death CTCAE_v5 Grade 5 Device Related Infection, CTCAE PT NCI Grade 5 Device related infection PT CTCAE_v5 ctcae5:C146279 Death Death Grade 5 Disease Progression, CTCAE Grade 5 Disease progression 10061818 C146279 Grade 5 Disease progression Grade 5 Disease progression Death NCI Death CTCAE_v5 Grade 5 Disease Progression, CTCAE PT NCI Grade 5 Disease progression PT CTCAE_v5 ctcae5:C146281 Death Death Grade 5 Duodenal Hemorrhage, CTCAE Grade 5 Duodenal hemorrhage 10055242 C146281 Grade 5 Duodenal hemorrhage Grade 5 Duodenal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Duodenal Hemorrhage, CTCAE PT NCI Grade 5 Duodenal hemorrhage PT CTCAE_v5 ctcae5:C146282 Death Death Grade 5 Duodenal Infection, CTCAE Grade 5 Duodenal infection 10065752 C146282 Grade 5 Duodenal infection Grade 5 Duodenal infection Death NCI Death CTCAE_v5 Grade 5 Duodenal Infection, CTCAE PT NCI Grade 5 Duodenal infection PT CTCAE_v5 ctcae5:C146283 Death Death Grade 5 Duodenal Obstruction, CTCAE Grade 5 Duodenal obstruction 10013830 C146283 Grade 5 Duodenal obstruction Grade 5 Duodenal obstruction Death NCI Death CTCAE_v5 Grade 5 Duodenal Obstruction, CTCAE PT NCI Grade 5 Duodenal obstruction PT CTCAE_v5 ctcae5:C146284 Death Death Grade 5 Duodenal Perforation, CTCAE Grade 5 Duodenal perforation 10013832 C146284 Grade 5 Duodenal perforation Grade 5 Duodenal perforation Death NCI Death CTCAE_v5 Grade 5 Duodenal Perforation, CTCAE PT NCI Grade 5 Duodenal perforation PT CTCAE_v5 ctcae5:C146285 Death Death Grade 5 Duodenal Stenosis, CTCAE Grade 5 Duodenal stenosis 10050094 C146285 Grade 5 Duodenal stenosis Grade 5 Duodenal stenosis Death NCI Death CTCAE_v5 Grade 5 Duodenal Stenosis, CTCAE PT NCI Grade 5 Duodenal stenosis PT CTCAE_v5 ctcae5:C146286 Death Death Grade 5 Duodenal Ulcer, CTCAE Grade 5 Duodenal ulcer 10013836 C146286 Grade 5 Duodenal ulcer Grade 5 Duodenal ulcer Death NCI Death CTCAE_v5 Grade 5 Duodenal Ulcer, CTCAE PT NCI Grade 5 Duodenal ulcer PT CTCAE_v5 ctcae5:C146287 Death Death Grade 5 Ear and Labyrinth Disorders - Other, Specify, CTCAE Grade 5 Ear and labyrinth disorders - Other, specify 10013993 C146287 Grade 5 Ear and labyrinth disorders - Other, specify Grade 5 Ear and labyrinth disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Ear and Labyrinth Disorders - Other, Specify, CTCAE PT NCI Grade 5 Ear and labyrinth disorders - Other, specify PT CTCAE_v5 ctcae5:C146288 Death Death Grade 5 Edema Cerebral, CTCAE Grade 5 Edema cerebral 10014217 C146288 Grade 5 Edema cerebral Grade 5 Edema cerebral Death NCI Death CTCAE_v5 Grade 5 Edema Cerebral, CTCAE PT NCI Grade 5 Edema cerebral PT CTCAE_v5 ctcae5:C146289 Death Death Grade 5 Encephalitis Infection, CTCAE Grade 5 Encephalitis infection 10014594 C146289 Grade 5 Encephalitis infection Grade 5 Encephalitis infection Death NCI Death CTCAE_v5 Grade 5 Encephalitis Infection, CTCAE PT NCI Grade 5 Encephalitis infection PT CTCAE_v5 ctcae5:C146290 Death Death Grade 5 Encephalomyelitis Infection, CTCAE Grade 5 Encephalomyelitis infection 10014621 C146290 Grade 5 Encephalomyelitis infection Grade 5 Encephalomyelitis infection Death NCI Death CTCAE_v5 Grade 5 Encephalomyelitis Infection, CTCAE PT NCI Grade 5 Encephalomyelitis infection PT CTCAE_v5 ctcae5:C146291 Death Death Grade 5 Endocarditis Infective, CTCAE Grade 5 Endocarditis infective 10014678 C146291 Grade 5 Endocarditis infective Grade 5 Endocarditis infective Death NCI Death CTCAE_v5 Grade 5 Endocarditis Infective, CTCAE PT NCI Grade 5 Endocarditis infective PT CTCAE_v5 ctcae5:C146292 Death Death Grade 5 Endocrine Disorders - Other, Specify, CTCAE Grade 5 Endocrine disorders - Other, specify 10014698 C146292 Grade 5 Endocrine disorders - Other, specify Grade 5 Endocrine disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Endocrine Disorders - Other, Specify, CTCAE PT NCI Grade 5 Endocrine disorders - Other, specify PT CTCAE_v5 ctcae5:C146293 Death Death Grade 5 Enterocolitis Infectious, CTCAE Grade 5 Enterocolitis infectious 10058838 C146293 Grade 5 Enterocolitis infectious Grade 5 Enterocolitis infectious Death NCI Death CTCAE_v5 Grade 5 Enterocolitis Infectious, CTCAE PT NCI Grade 5 Enterocolitis infectious PT CTCAE_v5 ctcae5:C146294 Death Death Grade 5 Enterocolitis Grade 5 Enterocolitis, CTCAE 10014893 C146294 Grade 5 Enterocolitis Grade 5 Enterocolitis Death NCI Death CTCAE_v5 Grade 5 Enterocolitis PT CTCAE_v5 Grade 5 Enterocolitis, CTCAE PT NCI ctcae5:C146295 Death Death Grade 5 Enterovesical Fistula, CTCAE Grade 5 Enterovesical fistula 10062570 C146295 Grade 5 Enterovesical fistula Grade 5 Enterovesical fistula Death NCI Death CTCAE_v5 Grade 5 Enterovesical Fistula, CTCAE PT NCI Grade 5 Enterovesical fistula PT CTCAE_v5 ctcae5:C146296 Death Death Grade 5 Epistaxis Grade 5 Epistaxis, CTCAE 10015090 C146296 Grade 5 Epistaxis Grade 5 Epistaxis Death NCI Death CTCAE_v5 Grade 5 Epistaxis PT CTCAE_v5 Grade 5 Epistaxis, CTCAE PT NCI ctcae5:C146297 Death Death Grade 5 Epstein-Barr Virus Infection Reactivation, CTCAE Grade 5 Epstein-Barr virus infection reactivation 10015109 C146297 Grade 5 Epstein-Barr virus infection reactivation Grade 5 Epstein-Barr virus infection reactivation Death NCI Death CTCAE_v5 Grade 5 Epstein-Barr Virus Infection Reactivation, CTCAE PT NCI Grade 5 Epstein-Barr virus infection reactivation PT CTCAE_v5 ctcae5:C146298 Death Death Grade 5 Erythema Multiforme, CTCAE Grade 5 Erythema multiforme 10015218 C146298 Grade 5 Erythema multiforme Grade 5 Erythema multiforme Death NCI Death CTCAE_v5 Grade 5 Erythema Multiforme, CTCAE PT NCI Grade 5 Erythema multiforme PT CTCAE_v5 ctcae5:C146299 Death Death Grade 5 Erythroderma Grade 5 Erythroderma, CTCAE 10015277 C146299 Grade 5 Erythroderma Grade 5 Erythroderma Death NCI Death CTCAE_v5 Grade 5 Erythroderma PT CTCAE_v5 Grade 5 Erythroderma, CTCAE PT NCI ctcae5:C146300 Death Death Grade 5 Esophageal Anastomotic Leak, CTCAE Grade 5 Esophageal anastomotic leak 10065961 C146300 Grade 5 Esophageal anastomotic leak Grade 5 Esophageal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Esophageal Anastomotic Leak, CTCAE PT NCI Grade 5 Esophageal anastomotic leak PT CTCAE_v5 ctcae5:C146302 Death Death Grade 5 Esophageal Hemorrhage, CTCAE Grade 5 Esophageal hemorrhage 10015384 C146302 Grade 5 Esophageal hemorrhage Grade 5 Esophageal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Esophageal Hemorrhage, CTCAE PT NCI Grade 5 Esophageal hemorrhage PT CTCAE_v5 ctcae5:C146303 Death Death Grade 5 Esophageal Infection, CTCAE Grade 5 Esophageal infection 10058804 C146303 Grade 5 Esophageal infection Grade 5 Esophageal infection Death NCI Death CTCAE_v5 Grade 5 Esophageal Infection, CTCAE PT NCI Grade 5 Esophageal infection PT CTCAE_v5 ctcae5:C146304 Death Death Grade 5 Esophageal Necrosis, CTCAE Grade 5 Esophageal necrosis 10065727 C146304 Grade 5 Esophageal necrosis Grade 5 Esophageal necrosis Death NCI Death CTCAE_v5 Grade 5 Esophageal Necrosis, CTCAE PT NCI Grade 5 Esophageal necrosis PT CTCAE_v5 ctcae5:C146305 Death Death Grade 5 Esophageal Obstruction, CTCAE Grade 5 Esophageal obstruction 10015387 C146305 Grade 5 Esophageal obstruction Grade 5 Esophageal obstruction Death NCI Death CTCAE_v5 Grade 5 Esophageal Obstruction, CTCAE PT NCI Grade 5 Esophageal obstruction PT CTCAE_v5 ctcae5:C146306 Death Death Grade 5 Esophageal Perforation, CTCAE Grade 5 Esophageal perforation 10055472 C146306 Grade 5 Esophageal perforation Grade 5 Esophageal perforation Death NCI Death CTCAE_v5 Grade 5 Esophageal Perforation, CTCAE PT NCI Grade 5 Esophageal perforation PT CTCAE_v5 ctcae5:C146307 Death Death Grade 5 Esophageal Stenosis, CTCAE Grade 5 Esophageal stenosis 10015448 C146307 Grade 5 Esophageal stenosis Grade 5 Esophageal stenosis Death NCI Death CTCAE_v5 Grade 5 Esophageal Stenosis, CTCAE PT NCI Grade 5 Esophageal stenosis PT CTCAE_v5 ctcae5:C146308 Death Death Grade 5 Esophageal Ulcer, CTCAE Grade 5 Esophageal ulcer 10015451 C146308 Grade 5 Esophageal ulcer Grade 5 Esophageal ulcer Death NCI Death CTCAE_v5 Grade 5 Esophageal Ulcer, CTCAE PT NCI Grade 5 Esophageal ulcer PT CTCAE_v5 ctcae5:C146309 Death Death Grade 5 Extrapyramidal Disorder, CTCAE Grade 5 Extrapyramidal disorder 10015832 C146309 Grade 5 Extrapyramidal disorder Grade 5 Extrapyramidal disorder Death NCI Death CTCAE_v5 Grade 5 Extrapyramidal Disorder, CTCAE PT NCI Grade 5 Extrapyramidal disorder PT CTCAE_v5 ctcae5:C146310 Death Death Grade 5 Eye Infection, CTCAE Grade 5 Eye infection 10015929 C146310 Grade 5 Eye infection Grade 5 Eye infection Death NCI Death CTCAE_v5 Grade 5 Eye Infection, CTCAE PT NCI Grade 5 Eye infection PT CTCAE_v5 ctcae5:C146311 Death Death Grade 5 Fallopian Tube Anastomotic Leak, CTCAE Grade 5 Fallopian tube anastomotic leak 10065788 C146311 Grade 5 Fallopian tube anastomotic leak Grade 5 Fallopian tube anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Fallopian Tube Anastomotic Leak, CTCAE PT NCI Grade 5 Fallopian tube anastomotic leak PT CTCAE_v5 ctcae5:C146313 Death Death Grade 5 Fever Grade 5 Fever, CTCAE 10016558 C146313 Grade 5 Fever Grade 5 Fever Death NCI Death CTCAE_v5 Grade 5 Fever PT CTCAE_v5 Grade 5 Fever, CTCAE PT NCI ctcae5:C146314 Death Death Grade 5 Fibrosis Deep Connective Tissue, CTCAE Grade 5 Fibrosis deep connective tissue 10065799 C146314 Grade 5 Fibrosis deep connective tissue Grade 5 Fibrosis deep connective tissue Death NCI Death CTCAE_v5 Grade 5 Fibrosis Deep Connective Tissue, CTCAE PT NCI Grade 5 Fibrosis deep connective tissue PT CTCAE_v5 ctcae5:C146315 Death Death Grade 5 Gallbladder Infection, CTCAE Grade 5 Gallbladder infection 10062632 C146315 Grade 5 Gallbladder infection Grade 5 Gallbladder infection Death NCI Death CTCAE_v5 Grade 5 Gallbladder Infection, CTCAE PT NCI Grade 5 Gallbladder infection PT CTCAE_v5 ctcae5:C146316 Death Death Grade 5 Gastric Anastomotic Leak, CTCAE Grade 5 Gastric anastomotic leak 10065893 C146316 Grade 5 Gastric anastomotic leak Grade 5 Gastric anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Gastric Anastomotic Leak, CTCAE PT NCI Grade 5 Gastric anastomotic leak PT CTCAE_v5 ctcae5:C146317 Death Death Grade 5 Gastric Fistula, CTCAE Grade 5 Gastric fistula 10065713 C146317 Grade 5 Gastric fistula Grade 5 Gastric fistula Death NCI Death CTCAE_v5 Grade 5 Gastric Fistula, CTCAE PT NCI Grade 5 Gastric fistula PT CTCAE_v5 ctcae5:C146318 Death Death Grade 5 Gastric Hemorrhage, CTCAE Grade 5 Gastric hemorrhage 10017789 C146318 Grade 5 Gastric hemorrhage Grade 5 Gastric hemorrhage Death NCI Death CTCAE_v5 Grade 5 Gastric Hemorrhage, CTCAE PT NCI Grade 5 Gastric hemorrhage PT CTCAE_v5 ctcae5:C146319 Death Death Grade 5 Gastric Necrosis, CTCAE Grade 5 Gastric necrosis 10051886 C146319 Grade 5 Gastric necrosis Grade 5 Gastric necrosis Death NCI Death CTCAE_v5 Grade 5 Gastric Necrosis, CTCAE PT NCI Grade 5 Gastric necrosis PT CTCAE_v5 ctcae5:C146320 Death Death Grade 5 Gastric Perforation, CTCAE Grade 5 Gastric perforation 10017815 C146320 Grade 5 Gastric perforation Grade 5 Gastric perforation Death NCI Death CTCAE_v5 Grade 5 Gastric Perforation, CTCAE PT NCI Grade 5 Gastric perforation PT CTCAE_v5 ctcae5:C146321 Death Death Grade 5 Gastric Stenosis, CTCAE Grade 5 Gastric stenosis 10061970 C146321 Grade 5 Gastric stenosis Grade 5 Gastric stenosis Death NCI Death CTCAE_v5 Grade 5 Gastric Stenosis, CTCAE PT NCI Grade 5 Gastric stenosis PT CTCAE_v5 ctcae5:C146322 Death Death Grade 5 Gastric Ulcer, CTCAE Grade 5 Gastric ulcer 10017822 C146322 Grade 5 Gastric ulcer Grade 5 Gastric ulcer Death NCI Death CTCAE_v5 Grade 5 Gastric Ulcer, CTCAE PT NCI Grade 5 Gastric ulcer PT CTCAE_v5 ctcae5:C146323 Death Death Grade 5 Gastrointestinal Anastomotic Leak, CTCAE Grade 5 Gastrointestinal anastomotic leak 10065879 C146323 Grade 5 Gastrointestinal anastomotic leak Grade 5 Gastrointestinal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Gastrointestinal Anastomotic Leak, CTCAE PT NCI Grade 5 Gastrointestinal anastomotic leak PT CTCAE_v5 ctcae5:C146324 Death Death Grade 5 Gastrointestinal Disorders - Other, Specify, CTCAE Grade 5 Gastrointestinal disorders - Other, specify 10017947 C146324 Grade 5 Gastrointestinal disorders - Other, specify Grade 5 Gastrointestinal disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Gastrointestinal Disorders - Other, Specify, CTCAE PT NCI Grade 5 Gastrointestinal disorders - Other, specify PT CTCAE_v5 ctcae5:C146325 Death Death Grade 5 Gastrointestinal Fistula, CTCAE Grade 5 Gastrointestinal fistula 10017877 C146325 Grade 5 Gastrointestinal fistula Grade 5 Gastrointestinal fistula Death NCI Death CTCAE_v5 Grade 5 Gastrointestinal Fistula, CTCAE PT NCI Grade 5 Gastrointestinal fistula PT CTCAE_v5 ctcae5:C146326 Death Death Grade 5 Gastrointestinal Stoma Necrosis, CTCAE Grade 5 Gastrointestinal stoma necrosis 10065712 C146326 Grade 5 Gastrointestinal stoma necrosis Grade 5 Gastrointestinal stoma necrosis Death NCI Death CTCAE_v5 Grade 5 Gastrointestinal Stoma Necrosis, CTCAE PT NCI Grade 5 Gastrointestinal stoma necrosis PT CTCAE_v5 ctcae5:C146327 Death Death Grade 5 General Disorders and Administration Site Conditions - Other, Specify, CTCAE Grade 5 General disorders and administration site conditions - Other, specify 10018065 C146327 Grade 5 General disorders and administration site conditions - Other, specify Grade 5 General disorders and administration site conditions - Other, specify Death NCI Death CTCAE_v5 Grade 5 General Disorders and Administration Site Conditions - Other, Specify, CTCAE PT NCI Grade 5 General disorders and administration site conditions - Other, specify PT CTCAE_v5 ctcae5:C146328 Death Death Grade 5 Glossopharyngeal Nerve Disorder, CTCAE Grade 5 Glossopharyngeal nerve disorder 10061185 C146328 Grade 5 Glossopharyngeal nerve disorder Grade 5 Glossopharyngeal nerve disorder Death NCI Death CTCAE_v5 Grade 5 Glossopharyngeal Nerve Disorder, CTCAE PT NCI Grade 5 Glossopharyngeal nerve disorder PT CTCAE_v5 ctcae5:C146329 Death Death Grade 5 Glucose Intolerance, CTCAE Grade 5 Glucose intolerance 10052426 C146329 Grade 5 Glucose intolerance Grade 5 Glucose intolerance Death NCI Death CTCAE_v5 Grade 5 Glucose Intolerance, CTCAE PT NCI Grade 5 Glucose intolerance PT CTCAE_v5 ctcae5:C146330 Death Death Grade 5 Guillain-Barre Syndrome, CTCAE Grade 5 Guillain-Barre syndrome 10018767 C146330 Grade 5 Guillain-Barre syndrome Grade 5 Guillain-Barre syndrome Death NCI Death CTCAE_v5 Grade 5 Guillain-Barre Syndrome, CTCAE PT NCI Grade 5 Guillain-Barre syndrome PT CTCAE_v5 ctcae5:C146331 Death Death Grade 5 Gum Infection, CTCAE Grade 5 Gum infection 10018784 C146331 Grade 5 Gum infection Grade 5 Gum infection Death NCI Death CTCAE_v5 Grade 5 Gum Infection, CTCAE PT NCI Grade 5 Gum infection PT CTCAE_v5 ctcae5:C146332 Death Death Grade 5 Hallucinations Grade 5 Hallucinations, CTCAE 10019077 C146332 Grade 5 Hallucinations Grade 5 Hallucinations Death NCI Death CTCAE_v5 Grade 5 Hallucinations PT CTCAE_v5 Grade 5 Hallucinations, CTCAE PT NCI ctcae5:C146333 Death Death Grade 5 Heart Failure, CTCAE Grade 5 Heart failure 10019279 C146333 Grade 5 Heart failure Grade 5 Heart failure Death NCI Death CTCAE_v5 Grade 5 Heart Failure, CTCAE PT NCI Grade 5 Heart failure PT CTCAE_v5 ctcae5:C146334 Death Death Grade 5 Hematosalpinx Grade 5 Hematosalpinx, CTCAE 10060602 C146334 Grade 5 Hematosalpinx Grade 5 Hematosalpinx Death NCI Death CTCAE_v5 Grade 5 Hematosalpinx PT CTCAE_v5 Grade 5 Hematosalpinx, CTCAE PT NCI ctcae5:C146335 Death Death Grade 5 Hematuria Grade 5 Hematuria, CTCAE 10019450 C146335 Grade 5 Hematuria Grade 5 Hematuria Death NCI Death CTCAE_v5 Grade 5 Hematuria PT CTCAE_v5 Grade 5 Hematuria, CTCAE PT NCI ctcae5:C146336 Death Death Grade 5 Hemolytic Uremic Syndrome, CTCAE Grade 5 Hemolytic uremic syndrome 10019515 C146336 Grade 5 Hemolytic uremic syndrome Grade 5 Hemolytic uremic syndrome Death NCI Death CTCAE_v5 Grade 5 Hemolytic Uremic Syndrome, CTCAE PT NCI Grade 5 Hemolytic uremic syndrome PT CTCAE_v5 ctcae5:C146337 Death Death Grade 5 Hemorrhoidal Hemorrhage, CTCAE Grade 5 Hemorrhoidal hemorrhage 10060640 C146337 Grade 5 Hemorrhoidal hemorrhage Grade 5 Hemorrhoidal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Hemorrhoidal Hemorrhage, CTCAE PT NCI Grade 5 Hemorrhoidal hemorrhage PT CTCAE_v5 ctcae5:C146338 Death Death Grade 5 Hepatic Failure, CTCAE Grade 5 Hepatic failure 10019663 C146338 Grade 5 Hepatic failure Grade 5 Hepatic failure Death NCI Death CTCAE_v5 Grade 5 Hepatic Failure, CTCAE PT NCI Grade 5 Hepatic failure PT CTCAE_v5 ctcae5:C146339 Death Death Grade 5 Hepatic Hemorrhage, CTCAE Grade 5 Hepatic hemorrhage 10019678 C146339 Grade 5 Hepatic hemorrhage Grade 5 Hepatic hemorrhage Death NCI Death CTCAE_v5 Grade 5 Hepatic Hemorrhage, CTCAE PT NCI Grade 5 Hepatic hemorrhage PT CTCAE_v5 ctcae5:C146340 Death Death Grade 5 Hepatic Infection, CTCAE Grade 5 Hepatic infection 10056522 C146340 Grade 5 Hepatic infection Grade 5 Hepatic infection Death NCI Death CTCAE_v5 Grade 5 Hepatic Infection, CTCAE PT NCI Grade 5 Hepatic infection PT CTCAE_v5 ctcae5:C146341 Death Death Grade 5 Hepatitis B Reactivation, CTCAE Grade 5 Hepatitis B reactivation 10058827 C146341 Grade 5 Hepatitis B reactivation Grade 5 Hepatitis B reactivation Death NCI Death CTCAE_v5 Grade 5 Hepatitis B Reactivation, CTCAE PT NCI Grade 5 Hepatitis B reactivation PT CTCAE_v5 ctcae5:C146342 Death Death Grade 5 Hepatitis Viral, CTCAE Grade 5 Hepatitis viral 10019799 C146342 Grade 5 Hepatitis viral Grade 5 Hepatitis viral Death NCI Death CTCAE_v5 Grade 5 Hepatitis Viral, CTCAE PT NCI Grade 5 Hepatitis viral PT CTCAE_v5 ctcae5:C146343 Death Death Grade 5 Hepatobiliary Disorders - Other, Specify, CTCAE Grade 5 Hepatobiliary disorders - Other, specify 10019805 C146343 Grade 5 Hepatobiliary disorders - Other, specify Grade 5 Hepatobiliary disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Hepatobiliary Disorders - Other, Specify, CTCAE PT NCI Grade 5 Hepatobiliary disorders - Other, specify PT CTCAE_v5 ctcae5:C146344 Death Death Grade 5 Herpes Simplex Reactivation, CTCAE Grade 5 Herpes simplex reactivation 10080137 C146344 Grade 5 Herpes simplex reactivation Grade 5 Herpes simplex reactivation Death NCI Death CTCAE_v5 Grade 5 Herpes Simplex Reactivation, CTCAE PT NCI Grade 5 Herpes simplex reactivation PT CTCAE_v5 ctcae5:C146345 Death Death Grade 5 Hypercalcemia Grade 5 Hypercalcemia, CTCAE 10020587 C146345 Grade 5 Hypercalcemia Grade 5 Hypercalcemia Death NCI Death CTCAE_v5 Grade 5 Hypercalcemia PT CTCAE_v5 Grade 5 Hypercalcemia, CTCAE PT NCI ctcae5:C146346 Death Death Grade 5 Hyperglycemia Grade 5 Hyperglycemia, CTCAE 10020639 C146346 Grade 5 Hyperglycemia Grade 5 Hyperglycemia Death NCI Death CTCAE_v5 Grade 5 Hyperglycemia PT CTCAE_v5 Grade 5 Hyperglycemia, CTCAE PT NCI ctcae5:C146347 Death Death Grade 5 Hyperkalemia Grade 5 Hyperkalemia, CTCAE 10020647 C146347 Grade 5 Hyperkalemia Grade 5 Hyperkalemia Death NCI Death CTCAE_v5 Grade 5 Hyperkalemia PT CTCAE_v5 Grade 5 Hyperkalemia, CTCAE PT NCI ctcae5:C146348 Death Death Grade 5 Hypermagnesemia Grade 5 Hypermagnesemia, CTCAE 10020670 C146348 Grade 5 Hypermagnesemia Grade 5 Hypermagnesemia Death NCI Death CTCAE_v5 Grade 5 Hypermagnesemia PT CTCAE_v5 Grade 5 Hypermagnesemia, CTCAE PT NCI ctcae5:C146349 Death Death Grade 5 Hypernatremia Grade 5 Hypernatremia, CTCAE 10020680 C146349 Grade 5 Hypernatremia Grade 5 Hypernatremia Death NCI Death CTCAE_v5 Grade 5 Hypernatremia PT CTCAE_v5 Grade 5 Hypernatremia, CTCAE PT NCI ctcae5:C146350 Death Death Grade 5 Hyperphosphatemia Grade 5 Hyperphosphatemia, CTCAE 10020712 C146350 Grade 5 Hyperphosphatemia Grade 5 Hyperphosphatemia Death NCI Death CTCAE_v5 Grade 5 Hyperphosphatemia PT CTCAE_v5 Grade 5 Hyperphosphatemia, CTCAE PT NCI ctcae5:C146351 Death Death Grade 5 Hyperthyroidism Grade 5 Hyperthyroidism, CTCAE 10020850 C146351 Grade 5 Hyperthyroidism Grade 5 Hyperthyroidism Death NCI Death CTCAE_v5 Grade 5 Hyperthyroidism PT CTCAE_v5 Grade 5 Hyperthyroidism, CTCAE PT NCI ctcae5:C146352 Death Death Grade 5 Hypertriglyceridemia Grade 5 Hypertriglyceridemia, CTCAE 10020870 C146352 Grade 5 Hypertriglyceridemia Grade 5 Hypertriglyceridemia Death NCI Death CTCAE_v5 Grade 5 Hypertriglyceridemia PT CTCAE_v5 Grade 5 Hypertriglyceridemia, CTCAE PT NCI ctcae5:C146353 Death Death Grade 5 Hyperuricemia Grade 5 Hyperuricemia, CTCAE 10020907 C146353 Grade 5 Hyperuricemia Grade 5 Hyperuricemia Death NCI Death CTCAE_v5 Grade 5 Hyperuricemia PT CTCAE_v5 Grade 5 Hyperuricemia, CTCAE PT NCI ctcae5:C146354 Death Death Grade 5 Hypoalbuminemia Grade 5 Hypoalbuminemia, CTCAE 10020943 C146354 Grade 5 Hypoalbuminemia Grade 5 Hypoalbuminemia Death NCI Death CTCAE_v5 Grade 5 Hypoalbuminemia PT CTCAE_v5 Grade 5 Hypoalbuminemia, CTCAE PT NCI ctcae5:C146355 Death Death Grade 5 Hypocalcemia Grade 5 Hypocalcemia, CTCAE 10020949 C146355 Grade 5 Hypocalcemia Grade 5 Hypocalcemia Death NCI Death CTCAE_v5 Grade 5 Hypocalcemia PT CTCAE_v5 Grade 5 Hypocalcemia, CTCAE PT NCI ctcae5:C146356 Death Death Grade 5 Hypoglycemia Grade 5 Hypoglycemia, CTCAE 10021005 C146356 Grade 5 Hypoglycemia Grade 5 Hypoglycemia Death NCI Death CTCAE_v5 Grade 5 Hypoglycemia PT CTCAE_v5 Grade 5 Hypoglycemia, CTCAE PT NCI ctcae5:C146357 Death Death Grade 5 Hypohidrosis Grade 5 Hypohidrosis, CTCAE 10021013 C146357 Grade 5 Hypohidrosis Grade 5 Hypohidrosis Death NCI Death CTCAE_v5 Grade 5 Hypohidrosis PT CTCAE_v5 Grade 5 Hypohidrosis, CTCAE PT NCI ctcae5:C146358 Death Death Grade 5 Hypokalemia Grade 5 Hypokalemia, CTCAE 10021018 C146358 Grade 5 Hypokalemia Grade 5 Hypokalemia Death NCI Death CTCAE_v5 Grade 5 Hypokalemia PT CTCAE_v5 Grade 5 Hypokalemia, CTCAE PT NCI ctcae5:C146359 Death Death Grade 5 Hypomagnesemia Grade 5 Hypomagnesemia, CTCAE 10021028 C146359 Grade 5 Hypomagnesemia Grade 5 Hypomagnesemia Death NCI Death CTCAE_v5 Grade 5 Hypomagnesemia PT CTCAE_v5 Grade 5 Hypomagnesemia, CTCAE PT NCI ctcae5:C146360 Death Death Grade 5 Hyponatremia Grade 5 Hyponatremia, CTCAE 10021038 C146360 Grade 5 Hyponatremia Grade 5 Hyponatremia Death NCI Death CTCAE_v5 Grade 5 Hyponatremia PT CTCAE_v5 Grade 5 Hyponatremia, CTCAE PT NCI ctcae5:C146361 Death Death Grade 5 Hypoparathyroidism Grade 5 Hypoparathyroidism, CTCAE 10021041 C146361 Grade 5 Hypoparathyroidism Grade 5 Hypoparathyroidism Death NCI Death CTCAE_v5 Grade 5 Hypoparathyroidism PT CTCAE_v5 Grade 5 Hypoparathyroidism, CTCAE PT NCI ctcae5:C146362 Death Death Grade 5 Hypophosphatemia Grade 5 Hypophosphatemia, CTCAE 10021059 C146362 Grade 5 Hypophosphatemia Grade 5 Hypophosphatemia Death NCI Death CTCAE_v5 Grade 5 Hypophosphatemia PT CTCAE_v5 Grade 5 Hypophosphatemia, CTCAE PT NCI ctcae5:C146363 Death Death Grade 5 Hypophysitis Grade 5 Hypophysitis, CTCAE 10062767 C146363 Grade 5 Hypophysitis Grade 5 Hypophysitis Death NCI Death CTCAE_v5 Grade 5 Hypophysitis PT CTCAE_v5 Grade 5 Hypophysitis, CTCAE PT NCI ctcae5:C146364 Death Death Grade 5 Hypopituitarism Grade 5 Hypopituitarism, CTCAE 10021067 C146364 Grade 5 Hypopituitarism Grade 5 Hypopituitarism Death NCI Death CTCAE_v5 Grade 5 Hypopituitarism PT CTCAE_v5 Grade 5 Hypopituitarism, CTCAE PT NCI ctcae5:C146365 Death Death Grade 5 Hypothyroidism Grade 5 Hypothyroidism, CTCAE 10021114 C146365 Grade 5 Hypothyroidism Grade 5 Hypothyroidism Death NCI Death CTCAE_v5 Grade 5 Hypothyroidism PT CTCAE_v5 Grade 5 Hypothyroidism, CTCAE PT NCI ctcae5:C146369 Death Death Grade 5 Ileal Perforation, CTCAE Grade 5 Ileal perforation 10021305 C146369 Grade 5 Ileal perforation Grade 5 Ileal perforation Death NCI Death CTCAE_v5 Grade 5 Ileal Perforation, CTCAE PT NCI Grade 5 Ileal perforation PT CTCAE_v5 ctcae5:C146370 Death Death Grade 5 Ileal Stenosis, CTCAE Grade 5 Ileal stenosis 10021307 C146370 Grade 5 Ileal stenosis Grade 5 Ileal stenosis Death NCI Death CTCAE_v5 Grade 5 Ileal Stenosis, CTCAE PT NCI Grade 5 Ileal stenosis PT CTCAE_v5 ctcae5:C146373 Death Death Grade 5 Immune System Disorders - Other, Specify, CTCAE Grade 5 Immune system disorders - Other, specify 10021428 C146373 Grade 5 Immune system disorders - Other, specify Grade 5 Immune system disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Immune System Disorders - Other, Specify, CTCAE PT NCI Grade 5 Immune system disorders - Other, specify PT CTCAE_v5 ctcae5:C146374 Death Death Grade 5 Infections and Infestations - Other, Specify, CTCAE Grade 5 Infections and infestations - Other, specify 10021881 C146374 Grade 5 Infections and infestations - Other, specify Grade 5 Infections and infestations - Other, specify Death NCI Death CTCAE_v5 Grade 5 Infections and Infestations - Other, Specify, CTCAE PT NCI Grade 5 Infections and infestations - Other, specify PT CTCAE_v5 ctcae5:C146375 Death Death Grade 5 Infective Myositis, CTCAE Grade 5 Infective myositis 10021918 C146375 Grade 5 Infective myositis Grade 5 Infective myositis Death NCI Death CTCAE_v5 Grade 5 Infective Myositis, CTCAE PT NCI Grade 5 Infective myositis PT CTCAE_v5 ctcae5:C146376 Death Death Grade 5 Infusion Related Reaction, CTCAE Grade 5 Infusion related reaction 10051792 C146376 Grade 5 Infusion related reaction Grade 5 Infusion related reaction Death NCI Death CTCAE_v5 Grade 5 Infusion Related Reaction, CTCAE PT NCI Grade 5 Infusion related reaction PT CTCAE_v5 ctcae5:C146377 Death Death Grade 5 Infusion Site Extravasation, CTCAE Grade 5 Infusion site extravasation 10064774 C146377 Grade 5 Infusion site extravasation Grade 5 Infusion site extravasation Death NCI Death CTCAE_v5 Grade 5 Infusion Site Extravasation, CTCAE PT NCI Grade 5 Infusion site extravasation PT CTCAE_v5 ctcae5:C146378 Death Death Grade 5 Injection Site Reaction, CTCAE Grade 5 Injection site reaction 10022095 C146378 Grade 5 Injection site reaction Grade 5 Injection site reaction Death NCI Death CTCAE_v5 Grade 5 Injection Site Reaction, CTCAE PT NCI Grade 5 Injection site reaction PT CTCAE_v5 ctcae5:C146379 Death Death Grade 5 Injury To Carotid Artery, CTCAE Grade 5 Injury to carotid artery 10022161 C146379 Grade 5 Injury to carotid artery Grade 5 Injury to carotid artery Death NCI Death CTCAE_v5 Grade 5 Injury To Carotid Artery, CTCAE PT NCI Grade 5 Injury to carotid artery PT CTCAE_v5 ctcae5:C146381 Death Death Grade 5 Injury To Jugular Vein, CTCAE Grade 5 Injury to jugular vein 10065849 C146381 Grade 5 Injury to jugular vein Grade 5 Injury to jugular vein Death NCI Death CTCAE_v5 Grade 5 Injury To Jugular Vein, CTCAE PT NCI Grade 5 Injury to jugular vein PT CTCAE_v5 ctcae5:C146382 Death Death Grade 5 Injury To Superior Vena Cava, CTCAE Grade 5 Injury to superior vena cava 10022356 C146382 Grade 5 Injury to superior vena cava Grade 5 Injury to superior vena cava Death NCI Death CTCAE_v5 Grade 5 Injury To Superior Vena Cava, CTCAE PT NCI Grade 5 Injury to superior vena cava PT CTCAE_v5 ctcae5:C146383 Death Death Grade 5 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE Grade 5 Injury, poisoning and procedural complications - Other, specify 10022117 C146383 Grade 5 Injury, poisoning and procedural complications - Other, specify Grade 5 Injury, poisoning and procedural complications - Other, specify Death NCI Death CTCAE_v5 Grade 5 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE PT NCI Grade 5 Injury, poisoning and procedural complications - Other, specify PT CTCAE_v5 ctcae5:C146384 Death Death Grade 5 Intestinal Stoma Leak, CTCAE Grade 5 Intestinal stoma leak 10059095 C146384 Grade 5 Intestinal stoma leak Grade 5 Intestinal stoma leak Death NCI Death CTCAE_v5 Grade 5 Intestinal Stoma Leak, CTCAE PT NCI Grade 5 Intestinal stoma leak PT CTCAE_v5 ctcae5:C146385 Death Death Grade 5 Intestinal Stoma Obstruction, CTCAE Grade 5 Intestinal stoma obstruction 10059094 C146385 Grade 5 Intestinal stoma obstruction Grade 5 Intestinal stoma obstruction Death NCI Death CTCAE_v5 Grade 5 Intestinal Stoma Obstruction, CTCAE PT NCI Grade 5 Intestinal stoma obstruction PT CTCAE_v5 ctcae5:C146386 Death Death Grade 5 Intestinal Stoma Site Bleeding, CTCAE Grade 5 Intestinal stoma site bleeding 10049468 C146386 Grade 5 Intestinal stoma site bleeding Grade 5 Intestinal stoma site bleeding Death NCI Death CTCAE_v5 Grade 5 Intestinal Stoma Site Bleeding, CTCAE PT NCI Grade 5 Intestinal stoma site bleeding PT CTCAE_v5 ctcae5:C146387 Death Death Grade 5 Intra-Abdominal Hemorrhage, CTCAE Grade 5 Intra-abdominal hemorrhage 10055291 C146387 Grade 5 Intra-abdominal hemorrhage Grade 5 Intra-abdominal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Intra-Abdominal Hemorrhage, CTCAE PT NCI Grade 5 Intra-abdominal hemorrhage PT CTCAE_v5 ctcae5:C146388 Death Death Grade 5 Intracranial Hemorrhage, CTCAE Grade 5 Intracranial hemorrhage 10022763 C146388 Grade 5 Intracranial hemorrhage Grade 5 Intracranial hemorrhage Death NCI Death CTCAE_v5 Grade 5 Intracranial Hemorrhage, CTCAE PT NCI Grade 5 Intracranial hemorrhage PT CTCAE_v5 ctcae5:C146389 Death Death Grade 5 Intraoperative Arterial Injury, CTCAE Grade 5 Intraoperative arterial injury 10065826 C146389 Grade 5 Intraoperative arterial injury Grade 5 Intraoperative arterial injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Arterial Injury, CTCAE PT NCI Grade 5 Intraoperative arterial injury PT CTCAE_v5 ctcae5:C146390 Death Death Grade 5 Intraoperative Breast Injury, CTCAE Grade 5 Intraoperative breast injury 10065831 C146390 Grade 5 Intraoperative breast injury Grade 5 Intraoperative breast injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Breast Injury, CTCAE PT NCI Grade 5 Intraoperative breast injury PT CTCAE_v5 ctcae5:C146391 Death Death Grade 5 Intraoperative Cardiac Injury, CTCAE Grade 5 Intraoperative cardiac injury 10065843 C146391 Grade 5 Intraoperative cardiac injury Grade 5 Intraoperative cardiac injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Cardiac Injury, CTCAE PT NCI Grade 5 Intraoperative cardiac injury PT CTCAE_v5 ctcae5:C146392 Death Death Grade 5 Intraoperative Ear Injury, CTCAE Grade 5 Intraoperative ear injury 10065844 C146392 Grade 5 Intraoperative ear injury Grade 5 Intraoperative ear injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Ear Injury, CTCAE PT NCI Grade 5 Intraoperative ear injury PT CTCAE_v5 ctcae5:C146393 Death Death Grade 5 Intraoperative Endocrine Injury, CTCAE Grade 5 Intraoperative endocrine injury 10065834 C146393 Grade 5 Intraoperative endocrine injury Grade 5 Intraoperative endocrine injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Endocrine Injury, CTCAE PT NCI Grade 5 Intraoperative endocrine injury PT CTCAE_v5 ctcae5:C146394 Death Death Grade 5 Intraoperative Gastrointestinal Injury, CTCAE Grade 5 Intraoperative gastrointestinal injury 10065825 C146394 Grade 5 Intraoperative gastrointestinal injury Grade 5 Intraoperative gastrointestinal injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Gastrointestinal Injury, CTCAE PT NCI Grade 5 Intraoperative gastrointestinal injury PT CTCAE_v5 ctcae5:C146395 Death Death Grade 5 Intraoperative Head and Neck Injury, CTCAE Grade 5 Intraoperative head and neck injury 10065842 C146395 Grade 5 Intraoperative head and neck injury Grade 5 Intraoperative head and neck injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Head and Neck Injury, CTCAE PT NCI Grade 5 Intraoperative head and neck injury PT CTCAE_v5 ctcae5:C146396 Death Death Grade 5 Intraoperative Hemorrhage, CTCAE Grade 5 Intraoperative hemorrhage 10055298 C146396 Grade 5 Intraoperative hemorrhage Grade 5 Intraoperative hemorrhage Death NCI Death CTCAE_v5 Grade 5 Intraoperative Hemorrhage, CTCAE PT NCI Grade 5 Intraoperative hemorrhage PT CTCAE_v5 ctcae5:C146397 Death Death Grade 5 Intraoperative Hepatobiliary Injury, CTCAE Grade 5 Intraoperative hepatobiliary injury 10065827 C146397 Grade 5 Intraoperative hepatobiliary injury Grade 5 Intraoperative hepatobiliary injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Hepatobiliary Injury, CTCAE PT NCI Grade 5 Intraoperative hepatobiliary injury PT CTCAE_v5 ctcae5:C146398 Death Death Grade 5 Intraoperative Musculoskeletal Injury, CTCAE Grade 5 Intraoperative musculoskeletal injury 10065829 C146398 Grade 5 Intraoperative musculoskeletal injury Grade 5 Intraoperative musculoskeletal injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Musculoskeletal Injury, CTCAE PT NCI Grade 5 Intraoperative musculoskeletal injury PT CTCAE_v5 ctcae5:C146399 Death Death Grade 5 Intraoperative Neurological Injury, CTCAE Grade 5 Intraoperative neurological injury 10065830 C146399 Grade 5 Intraoperative neurological injury Grade 5 Intraoperative neurological injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Neurological Injury, CTCAE PT NCI Grade 5 Intraoperative neurological injury PT CTCAE_v5 ctcae5:C146400 Death Death Grade 5 Intraoperative Ocular Injury, CTCAE Grade 5 Intraoperative ocular injury 10065841 C146400 Grade 5 Intraoperative ocular injury Grade 5 Intraoperative ocular injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Ocular Injury, CTCAE PT NCI Grade 5 Intraoperative ocular injury PT CTCAE_v5 ctcae5:C146401 Death Death Grade 5 Intraoperative Renal Injury, CTCAE Grade 5 Intraoperative renal injury 10065845 C146401 Grade 5 Intraoperative renal injury Grade 5 Intraoperative renal injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Renal Injury, CTCAE PT NCI Grade 5 Intraoperative renal injury PT CTCAE_v5 ctcae5:C146402 Death Death Grade 5 Intraoperative Reproductive Tract Injury, CTCAE Grade 5 Intraoperative reproductive tract injury 10065840 C146402 Grade 5 Intraoperative reproductive tract injury Grade 5 Intraoperative reproductive tract injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Reproductive Tract Injury, CTCAE PT NCI Grade 5 Intraoperative reproductive tract injury PT CTCAE_v5 ctcae5:C146403 Death Death Grade 5 Intraoperative Respiratory Injury, CTCAE Grade 5 Intraoperative respiratory injury 10065832 C146403 Grade 5 Intraoperative respiratory injury Grade 5 Intraoperative respiratory injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Respiratory Injury, CTCAE PT NCI Grade 5 Intraoperative respiratory injury PT CTCAE_v5 ctcae5:C146404 Death Death Grade 5 Intraoperative Splenic Injury, CTCAE Grade 5 Intraoperative splenic injury 10065847 C146404 Grade 5 Intraoperative splenic injury Grade 5 Intraoperative splenic injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Splenic Injury, CTCAE PT NCI Grade 5 Intraoperative splenic injury PT CTCAE_v5 ctcae5:C146405 Death Death Grade 5 Intraoperative Urinary Injury, CTCAE Grade 5 Intraoperative urinary injury 10065828 C146405 Grade 5 Intraoperative urinary injury Grade 5 Intraoperative urinary injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Urinary Injury, CTCAE PT NCI Grade 5 Intraoperative urinary injury PT CTCAE_v5 ctcae5:C146406 Death Death Grade 5 Intraoperative Venous Injury, CTCAE Grade 5 Intraoperative venous injury 10065848 C146406 Grade 5 Intraoperative venous injury Grade 5 Intraoperative venous injury Death NCI Death CTCAE_v5 Grade 5 Intraoperative Venous Injury, CTCAE PT NCI Grade 5 Intraoperative venous injury PT CTCAE_v5 ctcae5:C146407 Death Death Grade 5 Investigations - Other, Specify, CTCAE Grade 5 Investigations - Other, specify 10022891 C146407 Grade 5 Investigations - Other, specify Grade 5 Investigations - Other, specify Death NCI Death CTCAE_v5 Grade 5 Investigations - Other, Specify, CTCAE PT NCI Grade 5 Investigations - Other, specify PT CTCAE_v5 ctcae5:C146411 Death Death Grade 5 Jejunal Perforation, CTCAE Grade 5 Jejunal perforation 10023174 C146411 Grade 5 Jejunal perforation Grade 5 Jejunal perforation Death NCI Death CTCAE_v5 Grade 5 Jejunal Perforation, CTCAE PT NCI Grade 5 Jejunal perforation PT CTCAE_v5 ctcae5:C146412 Death Death Grade 5 Jejunal Stenosis, CTCAE Grade 5 Jejunal stenosis 10023176 C146412 Grade 5 Jejunal stenosis Grade 5 Jejunal stenosis Death NCI Death CTCAE_v5 Grade 5 Jejunal Stenosis, CTCAE PT NCI Grade 5 Jejunal stenosis PT CTCAE_v5 ctcae5:C146414 Death Death Grade 5 Joint Infection, CTCAE Grade 5 Joint infection 10023216 C146414 Grade 5 Joint infection Grade 5 Joint infection Death NCI Death CTCAE_v5 Grade 5 Joint Infection, CTCAE PT NCI Grade 5 Joint infection PT CTCAE_v5 ctcae5:C146415 Death Death Grade 5 Kidney Anastomotic Leak, CTCAE Grade 5 Kidney anastomotic leak 10065803 C146415 Grade 5 Kidney anastomotic leak Grade 5 Kidney anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Kidney Anastomotic Leak, CTCAE PT NCI Grade 5 Kidney anastomotic leak PT CTCAE_v5 ctcae5:C146416 Death Death Grade 5 Kidney Infection, CTCAE Grade 5 Kidney infection 10023424 C146416 Grade 5 Kidney infection Grade 5 Kidney infection Death NCI Death CTCAE_v5 Grade 5 Kidney Infection, CTCAE PT NCI Grade 5 Kidney infection PT CTCAE_v5 ctcae5:C146417 Death Death Grade 5 Large Intestinal Anastomotic Leak, CTCAE Grade 5 Large intestinal anastomotic leak 10065891 C146417 Grade 5 Large intestinal anastomotic leak Grade 5 Large intestinal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Large Intestinal Anastomotic Leak, CTCAE PT NCI Grade 5 Large intestinal anastomotic leak PT CTCAE_v5 ctcae5:C146418 Death Death Grade 5 Laryngeal Edema, CTCAE Grade 5 Laryngeal edema 10023838 C146418 Grade 5 Laryngeal edema Grade 5 Laryngeal edema Death NCI Death CTCAE_v5 Grade 5 Laryngeal Edema, CTCAE PT NCI Grade 5 Laryngeal edema PT CTCAE_v5 ctcae5:C146421 Death Death Grade 5 Laryngeal Mucositis, CTCAE Grade 5 Laryngeal mucositis 10065880 C146421 Grade 5 Laryngeal mucositis Grade 5 Laryngeal mucositis Death NCI Death CTCAE_v5 Grade 5 Laryngeal Mucositis, CTCAE PT NCI Grade 5 Laryngeal mucositis PT CTCAE_v5 ctcae5:C146422 Death Death Grade 5 Laryngeal Obstruction, CTCAE Grade 5 Laryngeal obstruction 10059639 C146422 Grade 5 Laryngeal obstruction Grade 5 Laryngeal obstruction Death NCI Death CTCAE_v5 Grade 5 Laryngeal Obstruction, CTCAE PT NCI Grade 5 Laryngeal obstruction PT CTCAE_v5 ctcae5:C146423 Death Death Grade 5 Laryngeal Stenosis, CTCAE Grade 5 Laryngeal stenosis 10023862 C146423 Grade 5 Laryngeal stenosis Grade 5 Laryngeal stenosis Death NCI Death CTCAE_v5 Grade 5 Laryngeal Stenosis, CTCAE PT NCI Grade 5 Laryngeal stenosis PT CTCAE_v5 ctcae5:C146424 Death Death Grade 5 Laryngitis Grade 5 Laryngitis, CTCAE 10023874 C146424 Grade 5 Laryngitis Grade 5 Laryngitis Death NCI Death CTCAE_v5 Grade 5 Laryngitis PT CTCAE_v5 Grade 5 Laryngitis, CTCAE PT NCI ctcae5:C146425 Death Death Grade 5 Laryngopharyngeal Dysesthesia, CTCAE Grade 5 Laryngopharyngeal dysesthesia 10062667 C146425 Grade 5 Laryngopharyngeal dysesthesia Grade 5 Laryngopharyngeal dysesthesia Death NCI Death CTCAE_v5 Grade 5 Laryngopharyngeal Dysesthesia, CTCAE PT NCI Grade 5 Laryngopharyngeal dysesthesia PT CTCAE_v5 ctcae5:C146426 Death Death Grade 5 Laryngospasm Grade 5 Laryngospasm, CTCAE 10023891 C146426 Grade 5 Laryngospasm Grade 5 Laryngospasm Death NCI Death CTCAE_v5 Grade 5 Laryngospasm PT CTCAE_v5 Grade 5 Laryngospasm, CTCAE PT NCI ctcae5:C146427 Death Death Grade 5 Leukemia Secondary To Oncology Chemotherapy, CTCAE Grade 5 Leukemia secondary to oncology chemotherapy 10048293 C146427 Grade 5 Leukemia secondary to oncology chemotherapy Grade 5 Leukemia secondary to oncology chemotherapy Death NCI Death CTCAE_v5 Grade 5 Leukemia Secondary To Oncology Chemotherapy, CTCAE PT NCI Grade 5 Leukemia secondary to oncology chemotherapy PT CTCAE_v5 ctcae5:C146428 Death Death Grade 5 Leukocytosis Grade 5 Leukocytosis, CTCAE 10024378 C146428 Grade 5 Leukocytosis Grade 5 Leukocytosis Death NCI Death CTCAE_v5 Grade 5 Leukocytosis PT CTCAE_v5 Grade 5 Leukocytosis, CTCAE PT NCI ctcae5:C146429 Death Death Grade 5 Leukoencephalopathy Grade 5 Leukoencephalopathy, CTCAE 10024382 C146429 Grade 5 Leukoencephalopathy Grade 5 Leukoencephalopathy Death NCI Death CTCAE_v5 Grade 5 Leukoencephalopathy PT CTCAE_v5 Grade 5 Leukoencephalopathy, CTCAE PT NCI ctcae5:C146430 Death Death Grade 5 Lower Gastrointestinal Hemorrhage, CTCAE Grade 5 Lower gastrointestinal hemorrhage 10051746 C146430 Grade 5 Lower gastrointestinal hemorrhage Grade 5 Lower gastrointestinal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Lower Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 5 Lower gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C146431 Death Death Grade 5 Lung Infection, CTCAE Grade 5 Lung infection 10061229 C146431 Grade 5 Lung infection Grade 5 Lung infection Death NCI Death CTCAE_v5 Grade 5 Lung Infection, CTCAE PT NCI Grade 5 Lung infection PT CTCAE_v5 ctcae5:C146432 Death Death Grade 5 Lymph Gland Infection, CTCAE Grade 5 Lymph gland infection 10050823 C146432 Grade 5 Lymph gland infection Grade 5 Lymph gland infection Death NCI Death CTCAE_v5 Grade 5 Lymph Gland Infection, CTCAE PT NCI Grade 5 Lymph gland infection PT CTCAE_v5 ctcae5:C146433 Death Death Grade 5 Lymph Leakage, CTCAE Grade 5 Lymph leakage 10065773 C146433 Grade 5 Lymph leakage Grade 5 Lymph leakage Death NCI Death CTCAE_v5 Grade 5 Lymph Leakage, CTCAE PT NCI Grade 5 Lymph leakage PT CTCAE_v5 ctcae5:C146434 Death Death Grade 5 Mania Grade 5 Mania, CTCAE 10026749 C146434 Grade 5 Mania Grade 5 Mania Death NCI Death CTCAE_v5 Grade 5 Mania PT CTCAE_v5 Grade 5 Mania, CTCAE PT NCI ctcae5:C146436 Death Death Grade 5 Mediastinal Infection, CTCAE Grade 5 Mediastinal infection 10057483 C146436 Grade 5 Mediastinal infection Grade 5 Mediastinal infection Death NCI Death CTCAE_v5 Grade 5 Mediastinal Infection, CTCAE PT NCI Grade 5 Mediastinal infection PT CTCAE_v5 ctcae5:C146437 Death Death Grade 5 Meningismus Grade 5 Meningismus, CTCAE 10027198 C146437 Grade 5 Meningismus Grade 5 Meningismus Death NCI Death CTCAE_v5 Grade 5 Meningismus PT CTCAE_v5 Grade 5 Meningismus, CTCAE PT NCI ctcae5:C146438 Death Death Grade 5 Meningitis Grade 5 Meningitis, CTCAE 10027199 C146438 Grade 5 Meningitis Grade 5 Meningitis Death NCI Death CTCAE_v5 Grade 5 Meningitis PT CTCAE_v5 Grade 5 Meningitis, CTCAE PT NCI ctcae5:C146439 Death Death Grade 5 Menorrhagia Grade 5 Menorrhagia, CTCAE 10027313 C146439 Grade 5 Menorrhagia Grade 5 Menorrhagia Death NCI Death CTCAE_v5 Grade 5 Menorrhagia PT CTCAE_v5 Grade 5 Menorrhagia, CTCAE PT NCI ctcae5:C146440 Death Death Grade 5 Metabolism and Nutrition Disorders - Other, Specify, CTCAE Grade 5 Metabolism and nutrition disorders - Other, specify 10027433 C146440 Grade 5 Metabolism and nutrition disorders - Other, specify Grade 5 Metabolism and nutrition disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Metabolism and Nutrition Disorders - Other, Specify, CTCAE PT NCI Grade 5 Metabolism and nutrition disorders - Other, specify PT CTCAE_v5 ctcae5:C146441 Death Death Grade 5 Methemoglobinemia Grade 5 Methemoglobinemia, CTCAE 10027506 C146441 Grade 5 Methemoglobinemia Grade 5 Methemoglobinemia Death NCI Death CTCAE_v5 Grade 5 Methemoglobinemia PT CTCAE_v5 Grade 5 Methemoglobinemia, CTCAE PT NCI ctcae5:C146442 Death Death Grade 5 Middle Ear Inflammation, CTCAE Grade 5 Middle ear inflammation 10065838 C146442 Grade 5 Middle ear inflammation Grade 5 Middle ear inflammation Death NCI Death CTCAE_v5 Grade 5 Middle Ear Inflammation, CTCAE PT NCI Grade 5 Middle ear inflammation PT CTCAE_v5 ctcae5:C146443 Death Death Grade 5 Mitral Valve Disease, CTCAE Grade 5 Mitral valve disease 10061532 C146443 Grade 5 Mitral valve disease Grade 5 Mitral valve disease Death NCI Death CTCAE_v5 Grade 5 Mitral Valve Disease, CTCAE PT NCI Grade 5 Mitral valve disease PT CTCAE_v5 ctcae5:C146446 Death Death Grade 5 Mucosal Infection, CTCAE Grade 5 Mucosal infection 10065764 C146446 Grade 5 Mucosal infection Grade 5 Mucosal infection Death NCI Death CTCAE_v5 Grade 5 Mucosal Infection, CTCAE PT NCI Grade 5 Mucosal infection PT CTCAE_v5 ctcae5:C146447 Death Death Grade 5 Mucositis Oral, CTCAE Grade 5 Mucositis oral 10028130 C146447 Grade 5 Mucositis oral Grade 5 Mucositis oral Death NCI Death CTCAE_v5 Grade 5 Mucositis Oral, CTCAE PT NCI Grade 5 Mucositis oral PT CTCAE_v5 ctcae5:C146449 Death Death Grade 5 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE Grade 5 Musculoskeletal and connective tissue disorder - Other, specify 10028395 C146449 Grade 5 Musculoskeletal and connective tissue disorder - Other, specify Grade 5 Musculoskeletal and connective tissue disorder - Other, specify Death NCI Death CTCAE_v5 Grade 5 Musculoskeletal and Connective Tissue Disorder - Other, Specify, CTCAE PT NCI Grade 5 Musculoskeletal and connective tissue disorder - Other, specify PT CTCAE_v5 ctcae5:C146450 Death Death Grade 5 Myasthenia Gravis, CTCAE Grade 5 Myasthenia gravis 10028417 C146450 Grade 5 Myasthenia gravis Grade 5 Myasthenia gravis Death NCI Death CTCAE_v5 Grade 5 Myasthenia Gravis, CTCAE PT NCI Grade 5 Myasthenia gravis PT CTCAE_v5 ctcae5:C146451 Death Death Grade 5 Myelodysplastic Syndrome, CTCAE Grade 5 Myelodysplastic syndrome 10028533 C146451 Grade 5 Myelodysplastic syndrome Grade 5 Myelodysplastic syndrome Death NCI Death CTCAE_v5 Grade 5 Myelodysplastic Syndrome, CTCAE PT NCI Grade 5 Myelodysplastic syndrome PT CTCAE_v5 ctcae5:C146452 Death Death Grade 5 Myocardial Infarction, CTCAE Grade 5 Myocardial infarction 10028596 C146452 Grade 5 Myocardial infarction Grade 5 Myocardial infarction Death NCI Death CTCAE_v5 Grade 5 Myocardial Infarction, CTCAE PT NCI Grade 5 Myocardial infarction PT CTCAE_v5 ctcae5:C146453 Death Death Grade 5 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE Grade 5 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify 10029104 C146453 Grade 5 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Grade 5 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify Death NCI Death CTCAE_v5 Grade 5 Neoplasms Benign, Malignant and Unspecified (Incl Cysts and Polyps) - Other, Specify, CTCAE PT NCI Grade 5 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify PT CTCAE_v5 ctcae5:C146454 Death Death Grade 5 Nephrotic Syndrome, CTCAE Grade 5 Nephrotic syndrome 10029164 C146454 Grade 5 Nephrotic syndrome Grade 5 Nephrotic syndrome Death NCI Death CTCAE_v5 Grade 5 Nephrotic Syndrome, CTCAE PT NCI Grade 5 Nephrotic syndrome PT CTCAE_v5 ctcae5:C146455 Death Death Grade 5 Nervous System Disorders - Other, Specify, CTCAE Grade 5 Nervous system disorders - Other, specify 10029205 C146455 Grade 5 Nervous system disorders - Other, specify Grade 5 Nervous system disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Nervous System Disorders - Other, Specify, CTCAE PT NCI Grade 5 Nervous system disorders - Other, specify PT CTCAE_v5 ctcae5:C146456 Death Death Grade 5 Obstruction Gastric, CTCAE Grade 5 Obstruction gastric 10029957 C146456 Grade 5 Obstruction gastric Grade 5 Obstruction gastric Death NCI Death CTCAE_v5 Grade 5 Obstruction Gastric, CTCAE PT NCI Grade 5 Obstruction gastric PT CTCAE_v5 ctcae5:C146457 Death Death Grade 5 Oral Cavity Fistula, CTCAE Grade 5 Oral cavity fistula 10065720 C146457 Grade 5 Oral cavity fistula Grade 5 Oral cavity fistula Death NCI Death CTCAE_v5 Grade 5 Oral Cavity Fistula, CTCAE PT NCI Grade 5 Oral cavity fistula PT CTCAE_v5 ctcae5:C146459 Death Death Grade 5 Osteonecrosis of Jaw, CTCAE Grade 5 Osteonecrosis of jaw 10064658 C146459 Grade 5 Osteonecrosis of jaw Grade 5 Osteonecrosis of jaw Death NCI Death CTCAE_v5 Grade 5 Osteonecrosis of Jaw, CTCAE PT NCI Grade 5 Osteonecrosis of jaw PT CTCAE_v5 ctcae5:C146460 Death Death Grade 5 Osteonecrosis Grade 5 Osteonecrosis, CTCAE 10031264 C146460 Grade 5 Osteonecrosis Grade 5 Osteonecrosis Death NCI Death CTCAE_v5 Grade 5 Osteonecrosis PT CTCAE_v5 Grade 5 Osteonecrosis, CTCAE PT NCI ctcae5:C146461 Death Death Grade 5 Otitis Externa, CTCAE Grade 5 Otitis externa 10033072 C146461 Grade 5 Otitis externa Grade 5 Otitis externa Death NCI Death CTCAE_v5 Grade 5 Otitis Externa, CTCAE PT NCI Grade 5 Otitis externa PT CTCAE_v5 ctcae5:C146462 Death Death Grade 5 Otitis Media, CTCAE Grade 5 Otitis media 10033078 C146462 Grade 5 Otitis media Grade 5 Otitis media Death NCI Death CTCAE_v5 Grade 5 Otitis Media, CTCAE PT NCI Grade 5 Otitis media PT CTCAE_v5 ctcae5:C146464 Death Death Grade 5 Ovarian Infection, CTCAE Grade 5 Ovarian infection 10055005 C146464 Grade 5 Ovarian infection Grade 5 Ovarian infection Death NCI Death CTCAE_v5 Grade 5 Ovarian Infection, CTCAE PT NCI Grade 5 Ovarian infection PT CTCAE_v5 ctcae5:C146465 Death Death Grade 5 Ovarian Rupture, CTCAE Grade 5 Ovarian rupture 10033279 C146465 Grade 5 Ovarian rupture Grade 5 Ovarian rupture Death NCI Death CTCAE_v5 Grade 5 Ovarian Rupture, CTCAE PT NCI Grade 5 Ovarian rupture PT CTCAE_v5 ctcae5:C146466 Death Death Grade 5 Pancreas Infection, CTCAE Grade 5 Pancreas infection 10051741 C146466 Grade 5 Pancreas infection Grade 5 Pancreas infection Death NCI Death CTCAE_v5 Grade 5 Pancreas Infection, CTCAE PT NCI Grade 5 Pancreas infection PT CTCAE_v5 ctcae5:C146467 Death Death Grade 5 Pancreatic Anastomotic Leak, CTCAE Grade 5 Pancreatic anastomotic leak 10050457 C146467 Grade 5 Pancreatic anastomotic leak Grade 5 Pancreatic anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Pancreatic Anastomotic Leak, CTCAE PT NCI Grade 5 Pancreatic anastomotic leak PT CTCAE_v5 ctcae5:C146468 Death Death Grade 5 Pancreatic Duct Stenosis, CTCAE Grade 5 Pancreatic duct stenosis 10065703 C146468 Grade 5 Pancreatic duct stenosis Grade 5 Pancreatic duct stenosis Death NCI Death CTCAE_v5 Grade 5 Pancreatic Duct Stenosis, CTCAE PT NCI Grade 5 Pancreatic duct stenosis PT CTCAE_v5 ctcae5:C146471 Death Death Grade 5 Pancreatic Necrosis, CTCAE Grade 5 Pancreatic necrosis 10058096 C146471 Grade 5 Pancreatic necrosis Grade 5 Pancreatic necrosis Death NCI Death CTCAE_v5 Grade 5 Pancreatic Necrosis, CTCAE PT NCI Grade 5 Pancreatic necrosis PT CTCAE_v5 ctcae5:C146472 Death Death Grade 5 Papulopustular Rash, CTCAE Grade 5 Papulopustular rash 10069138 C146472 Grade 5 Papulopustular rash Grade 5 Papulopustular rash Death NCI Death CTCAE_v5 Grade 5 Papulopustular Rash, CTCAE PT NCI Grade 5 Papulopustular rash PT CTCAE_v5 ctcae5:C146473 Death Death Grade 5 Paroxysmal Atrial Tachycardia, CTCAE Grade 5 Paroxysmal atrial tachycardia 10034040 C146473 Grade 5 Paroxysmal atrial tachycardia Grade 5 Paroxysmal atrial tachycardia Death NCI Death CTCAE_v5 Grade 5 Paroxysmal Atrial Tachycardia, CTCAE PT NCI Grade 5 Paroxysmal atrial tachycardia PT CTCAE_v5 ctcae5:C146474 Death Death Grade 5 Pelvic Infection, CTCAE Grade 5 Pelvic infection 10058674 C146474 Grade 5 Pelvic infection Grade 5 Pelvic infection Death NCI Death CTCAE_v5 Grade 5 Pelvic Infection, CTCAE PT NCI Grade 5 Pelvic infection PT CTCAE_v5 ctcae5:C146475 Death Death Grade 5 Penile Infection, CTCAE Grade 5 Penile infection 10061912 C146475 Grade 5 Penile infection Grade 5 Penile infection Death NCI Death CTCAE_v5 Grade 5 Penile Infection, CTCAE PT NCI Grade 5 Penile infection PT CTCAE_v5 ctcae5:C146476 Death Death Grade 5 Perforation Bile Duct, CTCAE Grade 5 Perforation bile duct 10034405 C146476 Grade 5 Perforation bile duct Grade 5 Perforation bile duct Death NCI Death CTCAE_v5 Grade 5 Perforation Bile Duct, CTCAE PT NCI Grade 5 Perforation bile duct PT CTCAE_v5 ctcae5:C146477 Death Death Grade 5 Pericardial Effusion, CTCAE Grade 5 Pericardial effusion 10034474 C146477 Grade 5 Pericardial effusion Grade 5 Pericardial effusion Death NCI Death CTCAE_v5 Grade 5 Pericardial Effusion, CTCAE PT NCI Grade 5 Pericardial effusion PT CTCAE_v5 ctcae5:C146478 Death Death Grade 5 Pericardial Tamponade, CTCAE Grade 5 Pericardial tamponade 10053565 C146478 Grade 5 Pericardial tamponade Grade 5 Pericardial tamponade Death NCI Death CTCAE_v5 Grade 5 Pericardial Tamponade, CTCAE PT NCI Grade 5 Pericardial tamponade PT CTCAE_v5 ctcae5:C146479 Death Death Grade 5 Periorbital Infection, CTCAE Grade 5 Periorbital infection 10051472 C146479 Grade 5 Periorbital infection Grade 5 Periorbital infection Death NCI Death CTCAE_v5 Grade 5 Periorbital Infection, CTCAE PT NCI Grade 5 Periorbital infection PT CTCAE_v5 ctcae5:C146480 Death Death Grade 5 Peripheral Ischemia, CTCAE Grade 5 Peripheral ischemia 10034578 C146480 Grade 5 Peripheral ischemia Grade 5 Peripheral ischemia Death NCI Death CTCAE_v5 Grade 5 Peripheral Ischemia, CTCAE PT NCI Grade 5 Peripheral ischemia PT CTCAE_v5 ctcae5:C146481 Death Death Grade 5 Peripheral Motor Neuropathy, CTCAE Grade 5 Peripheral motor neuropathy 10034580 C146481 Grade 5 Peripheral motor neuropathy Grade 5 Peripheral motor neuropathy Death NCI Death CTCAE_v5 Grade 5 Peripheral Motor Neuropathy, CTCAE PT NCI Grade 5 Peripheral motor neuropathy PT CTCAE_v5 ctcae5:C146482 Death Death Grade 5 Peripheral Nerve Infection, CTCAE Grade 5 Peripheral nerve infection 10065766 C146482 Grade 5 Peripheral nerve infection Grade 5 Peripheral nerve infection Death NCI Death CTCAE_v5 Grade 5 Peripheral Nerve Infection, CTCAE PT NCI Grade 5 Peripheral nerve infection PT CTCAE_v5 ctcae5:C146483 Death Death Grade 5 Peritoneal Infection, CTCAE Grade 5 Peritoneal infection 10057262 C146483 Grade 5 Peritoneal infection Grade 5 Peritoneal infection Death NCI Death CTCAE_v5 Grade 5 Peritoneal Infection, CTCAE PT NCI Grade 5 Peritoneal infection PT CTCAE_v5 ctcae5:C146485 Death Death Grade 5 Pharyngeal Anastomotic Leak, CTCAE Grade 5 Pharyngeal anastomotic leak 10065705 C146485 Grade 5 Pharyngeal anastomotic leak Grade 5 Pharyngeal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Anastomotic Leak, CTCAE PT NCI Grade 5 Pharyngeal anastomotic leak PT CTCAE_v5 ctcae5:C146488 Death Death Grade 5 Pharyngeal Mucositis, CTCAE Grade 5 Pharyngeal mucositis 10065881 C146488 Grade 5 Pharyngeal mucositis Grade 5 Pharyngeal mucositis Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Mucositis, CTCAE PT NCI Grade 5 Pharyngeal mucositis PT CTCAE_v5 ctcae5:C146490 Death Death Grade 5 Pharyngeal Stenosis, CTCAE Grade 5 Pharyngeal stenosis 10050028 C146490 Grade 5 Pharyngeal stenosis Grade 5 Pharyngeal stenosis Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Stenosis, CTCAE PT NCI Grade 5 Pharyngeal stenosis PT CTCAE_v5 ctcae5:C146491 Death Death Grade 5 Pharyngitis Grade 5 Pharyngitis, CTCAE 10034835 C146491 Grade 5 Pharyngitis Grade 5 Pharyngitis Death NCI Death CTCAE_v5 Grade 5 Pharyngitis PT CTCAE_v5 Grade 5 Pharyngitis, CTCAE PT NCI ctcae5:C146492 Death Death Grade 5 Phlebitis Infective, CTCAE Grade 5 Phlebitis infective 10056627 C146492 Grade 5 Phlebitis infective Grade 5 Phlebitis infective Death NCI Death CTCAE_v5 Grade 5 Phlebitis Infective, CTCAE PT NCI Grade 5 Phlebitis infective PT CTCAE_v5 ctcae5:C146493 Death Death Grade 5 Pleural Effusion, CTCAE Grade 5 Pleural effusion 10035598 C146493 Grade 5 Pleural effusion Grade 5 Pleural effusion Death NCI Death CTCAE_v5 Grade 5 Pleural Effusion, CTCAE PT NCI Grade 5 Pleural effusion PT CTCAE_v5 ctcae5:C146495 Death Death Grade 5 Pleural Infection, CTCAE Grade 5 Pleural infection 10061351 C146495 Grade 5 Pleural infection Grade 5 Pleural infection Death NCI Death CTCAE_v5 Grade 5 Pleural Infection, CTCAE PT NCI Grade 5 Pleural infection PT CTCAE_v5 ctcae5:C146496 Death Death Grade 5 Pneumonitis Grade 5 Pneumonitis, CTCAE 10035742 C146496 Grade 5 Pneumonitis Grade 5 Pneumonitis Death NCI Death CTCAE_v5 Grade 5 Pneumonitis PT CTCAE_v5 Grade 5 Pneumonitis, CTCAE PT NCI ctcae5:C146497 Death Death Grade 5 Portal Hypertension, CTCAE Grade 5 Portal hypertension 10036200 C146497 Grade 5 Portal hypertension Grade 5 Portal hypertension Death NCI Death CTCAE_v5 Grade 5 Portal Hypertension, CTCAE PT NCI Grade 5 Portal hypertension PT CTCAE_v5 ctcae5:C146498 Death Death Grade 5 Portal Vein Thrombosis, CTCAE Grade 5 Portal vein thrombosis 10036206 C146498 Grade 5 Portal vein thrombosis Grade 5 Portal vein thrombosis Death NCI Death CTCAE_v5 Grade 5 Portal Vein Thrombosis, CTCAE PT NCI Grade 5 Portal vein thrombosis PT CTCAE_v5 ctcae5:C146499 Death Death Grade 5 Postoperative Hemorrhage, CTCAE Grade 5 Postoperative hemorrhage 10055322 C146499 Grade 5 Postoperative hemorrhage Grade 5 Postoperative hemorrhage Death NCI Death CTCAE_v5 Grade 5 Postoperative Hemorrhage, CTCAE PT NCI Grade 5 Postoperative hemorrhage PT CTCAE_v5 ctcae5:C146500 Death Death Grade 5 Postoperative Thoracic Procedure Complication, CTCAE Grade 5 Postoperative thoracic procedure complication 10056745 C146500 Grade 5 Postoperative thoracic procedure complication Grade 5 Postoperative thoracic procedure complication Death NCI Death CTCAE_v5 Grade 5 Postoperative Thoracic Procedure Complication, CTCAE PT NCI Grade 5 Postoperative thoracic procedure complication PT CTCAE_v5 ctcae5:C146501 Death Death Grade 5 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE Grade 5 Pregnancy, puerperium and perinatal conditions - Other, specify 10036585 C146501 Grade 5 Pregnancy, puerperium and perinatal conditions - Other, specify Grade 5 Pregnancy, puerperium and perinatal conditions - Other, specify Death NCI Death CTCAE_v5 Grade 5 Pregnancy, Puerperium and Perinatal Conditions - Other, Specify, CTCAE PT NCI Grade 5 Pregnancy, puerperium and perinatal conditions - Other, specify PT CTCAE_v5 ctcae5:C146502 Death Death Grade 5 Prolapse of Intestinal Stoma, CTCAE Grade 5 Prolapse of intestinal stoma 10065745 C146502 Grade 5 Prolapse of intestinal stoma Grade 5 Prolapse of intestinal stoma Death NCI Death CTCAE_v5 Grade 5 Prolapse of Intestinal Stoma, CTCAE PT NCI Grade 5 Prolapse of intestinal stoma PT CTCAE_v5 ctcae5:C146503 Death Death Grade 5 Prolapse of Urostomy, CTCAE Grade 5 Prolapse of urostomy 10065822 C146503 Grade 5 Prolapse of urostomy Grade 5 Prolapse of urostomy Death NCI Death CTCAE_v5 Grade 5 Prolapse of Urostomy, CTCAE PT NCI Grade 5 Prolapse of urostomy PT CTCAE_v5 ctcae5:C146504 Death Death Grade 5 Prostate Infection, CTCAE Grade 5 Prostate infection 10050662 C146504 Grade 5 Prostate infection Grade 5 Prostate infection Death NCI Death CTCAE_v5 Grade 5 Prostate Infection, CTCAE PT NCI Grade 5 Prostate infection PT CTCAE_v5 ctcae5:C146506 Death Death Grade 5 Psychiatric Disorders - Other, Specify, CTCAE Grade 5 Psychiatric disorders - Other, specify 10037175 C146506 Grade 5 Psychiatric disorders - Other, specify Grade 5 Psychiatric disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Psychiatric Disorders - Other, Specify, CTCAE PT NCI Grade 5 Psychiatric disorders - Other, specify PT CTCAE_v5 ctcae5:C146507 Death Death Grade 5 Psychosis Grade 5 Psychosis, CTCAE 10037234 C146507 Grade 5 Psychosis Grade 5 Psychosis Death NCI Death CTCAE_v5 Grade 5 Psychosis PT CTCAE_v5 Grade 5 Psychosis, CTCAE PT NCI ctcae5:C146508 Death Death Grade 5 Pulmonary Edema, CTCAE Grade 5 Pulmonary edema 10037375 C146508 Grade 5 Pulmonary edema Grade 5 Pulmonary edema Death NCI Death CTCAE_v5 Grade 5 Pulmonary Edema, CTCAE PT NCI Grade 5 Pulmonary edema PT CTCAE_v5 ctcae5:C146509 Death Death Grade 5 Pulmonary Fibrosis, CTCAE Grade 5 Pulmonary fibrosis 10037383 C146509 Grade 5 Pulmonary fibrosis Grade 5 Pulmonary fibrosis Death NCI Death CTCAE_v5 Grade 5 Pulmonary Fibrosis, CTCAE PT NCI Grade 5 Pulmonary fibrosis PT CTCAE_v5 ctcae5:C146510 Death Death Grade 5 Pulmonary Fistula, CTCAE Grade 5 Pulmonary fistula 10065873 C146510 Grade 5 Pulmonary fistula Grade 5 Pulmonary fistula Death NCI Death CTCAE_v5 Grade 5 Pulmonary Fistula, CTCAE PT NCI Grade 5 Pulmonary fistula PT CTCAE_v5 ctcae5:C146511 Death Death Grade 5 Pulmonary Valve Disease, CTCAE Grade 5 Pulmonary valve disease 10061541 C146511 Grade 5 Pulmonary valve disease Grade 5 Pulmonary valve disease Death NCI Death CTCAE_v5 Grade 5 Pulmonary Valve Disease, CTCAE PT NCI Grade 5 Pulmonary valve disease PT CTCAE_v5 ctcae5:C146512 Death Death Grade 5 Pyramidal Tract Syndrome, CTCAE Grade 5 Pyramidal tract syndrome 10063636 C146512 Grade 5 Pyramidal tract syndrome Grade 5 Pyramidal tract syndrome Death NCI Death CTCAE_v5 Grade 5 Pyramidal Tract Syndrome, CTCAE PT NCI Grade 5 Pyramidal tract syndrome PT CTCAE_v5 ctcae5:C146513 Death Death Grade 5 Radiation Recall Reaction (Dermatologic), CTCAE Grade 5 Radiation recall reaction (dermatologic) 10037767 C146513 Grade 5 Radiation recall reaction (dermatologic) Grade 5 Radiation recall reaction (dermatologic) Death NCI Death CTCAE_v5 Grade 5 Radiation Recall Reaction (Dermatologic), CTCAE PT NCI Grade 5 Radiation recall reaction (dermatologic) PT CTCAE_v5 ctcae5:C146514 Death Death Grade 5 Radiculitis Grade 5 Radiculitis, CTCAE 10061928 C146514 Grade 5 Radiculitis Grade 5 Radiculitis Death NCI Death CTCAE_v5 Grade 5 Radiculitis PT CTCAE_v5 Grade 5 Radiculitis, CTCAE PT NCI ctcae5:C146515 Death Death Grade 5 Rash Acneiform, CTCAE Grade 5 Rash acneiform 10037847 C146515 Grade 5 Rash acneiform Grade 5 Rash acneiform Death NCI Death CTCAE_v5 Grade 5 Rash Acneiform, CTCAE PT NCI Grade 5 Rash acneiform PT CTCAE_v5 ctcae5:C146516 Death Death Grade 5 Rectal Anastomotic Leak, CTCAE Grade 5 Rectal anastomotic leak 10065894 C146516 Grade 5 Rectal anastomotic leak Grade 5 Rectal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Rectal Anastomotic Leak, CTCAE PT NCI Grade 5 Rectal anastomotic leak PT CTCAE_v5 ctcae5:C146519 Death Death Grade 5 Rectal Mucositis, CTCAE Grade 5 Rectal mucositis 10063190 C146519 Grade 5 Rectal mucositis Grade 5 Rectal mucositis Death NCI Death CTCAE_v5 Grade 5 Rectal Mucositis, CTCAE PT NCI Grade 5 Rectal mucositis PT CTCAE_v5 ctcae5:C146523 Death Death Grade 5 Rectal Stenosis, CTCAE Grade 5 Rectal stenosis 10038079 C146523 Grade 5 Rectal stenosis Grade 5 Rectal stenosis Death NCI Death CTCAE_v5 Grade 5 Rectal Stenosis, CTCAE PT NCI Grade 5 Rectal stenosis PT CTCAE_v5 ctcae5:C146525 Death Death Grade 5 Recurrent Laryngeal Nerve Palsy, CTCAE Grade 5 Recurrent laryngeal nerve palsy 10038130 C146525 Grade 5 Recurrent laryngeal nerve palsy Grade 5 Recurrent laryngeal nerve palsy Death NCI Death CTCAE_v5 Grade 5 Recurrent Laryngeal Nerve Palsy, CTCAE PT NCI Grade 5 Recurrent laryngeal nerve palsy PT CTCAE_v5 ctcae5:C146526 Death Death Grade 5 Renal and Urinary Disorders - Other, Specify, CTCAE Grade 5 Renal and urinary disorders - Other, specify 10038359 C146526 Grade 5 Renal and urinary disorders - Other, specify Grade 5 Renal and urinary disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Renal and Urinary Disorders - Other, Specify, CTCAE PT NCI Grade 5 Renal and urinary disorders - Other, specify PT CTCAE_v5 ctcae5:C146527 Death Death Grade 5 Renal Calculi, CTCAE Grade 5 Renal calculi 10038385 C146527 Grade 5 Renal calculi Grade 5 Renal calculi Death NCI Death CTCAE_v5 Grade 5 Renal Calculi, CTCAE PT NCI Grade 5 Renal calculi PT CTCAE_v5 ctcae5:C146529 Death Death Grade 5 Reproductive System and Breast Disorders - Other, Specify, CTCAE Grade 5 Reproductive system and breast disorders - Other, specify 10038604 C146529 Grade 5 Reproductive system and breast disorders - Other, specify Grade 5 Reproductive system and breast disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Reproductive System and Breast Disorders - Other, Specify, CTCAE PT NCI Grade 5 Reproductive system and breast disorders - Other, specify PT CTCAE_v5 ctcae5:C146530 Death Death Grade 5 Respiratory Failure, CTCAE Grade 5 Respiratory failure 10038695 C146530 Grade 5 Respiratory failure Grade 5 Respiratory failure Death NCI Death CTCAE_v5 Grade 5 Respiratory Failure, CTCAE PT NCI Grade 5 Respiratory failure PT CTCAE_v5 ctcae5:C146531 Death Death Grade 5 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE Grade 5 Respiratory, thoracic and mediastinal disorders - Other, specify 10038738 C146531 Grade 5 Respiratory, thoracic and mediastinal disorders - Other, specify Grade 5 Respiratory, thoracic and mediastinal disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE PT NCI Grade 5 Respiratory, thoracic and mediastinal disorders - Other, specify PT CTCAE_v5 ctcae5:C146532 Death Death Grade 5 Retroperitoneal Hemorrhage, CTCAE Grade 5 Retroperitoneal hemorrhage 10038981 C146532 Grade 5 Retroperitoneal hemorrhage Grade 5 Retroperitoneal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Retroperitoneal Hemorrhage, CTCAE PT NCI Grade 5 Retroperitoneal hemorrhage PT CTCAE_v5 ctcae5:C146533 Death Death Grade 5 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE Grade 5 Reversible posterior leukoencephalopathy syndrome 10063761 C146533 Grade 5 Reversible posterior leukoencephalopathy syndrome Grade 5 Reversible posterior leukoencephalopathy syndrome Death NCI Death CTCAE_v5 Grade 5 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE PT NCI Grade 5 Reversible posterior leukoencephalopathy syndrome PT CTCAE_v5 ctcae5:C146534 Death Death Grade 5 Rhabdomyolysis Grade 5 Rhabdomyolysis, CTCAE 10039020 C146534 Grade 5 Rhabdomyolysis Grade 5 Rhabdomyolysis Death NCI Death CTCAE_v5 Grade 5 Rhabdomyolysis PT CTCAE_v5 Grade 5 Rhabdomyolysis, CTCAE PT NCI ctcae5:C146535 Death Death Grade 5 Salivary Duct Inflammation, CTCAE Grade 5 Salivary duct inflammation 10056681 C146535 Grade 5 Salivary duct inflammation Grade 5 Salivary duct inflammation Death NCI Death CTCAE_v5 Grade 5 Salivary Duct Inflammation, CTCAE PT NCI Grade 5 Salivary duct inflammation PT CTCAE_v5 ctcae5:C146536 Death Death Grade 5 Salivary Gland Infection, CTCAE Grade 5 Salivary gland infection 10039413 C146536 Grade 5 Salivary gland infection Grade 5 Salivary gland infection Death NCI Death CTCAE_v5 Grade 5 Salivary Gland Infection, CTCAE PT NCI Grade 5 Salivary gland infection PT CTCAE_v5 ctcae5:C146537 Death Death Grade 5 Scrotal Infection, CTCAE Grade 5 Scrotal infection 10062156 C146537 Grade 5 Scrotal infection Grade 5 Scrotal infection Death NCI Death CTCAE_v5 Grade 5 Scrotal Infection, CTCAE PT NCI Grade 5 Scrotal infection PT CTCAE_v5 ctcae5:C146538 Death Death Grade 5 Sepsis Grade 5 Sepsis, CTCAE 10040047 C146538 Grade 5 Sepsis Grade 5 Sepsis Death NCI Death CTCAE_v5 Grade 5 Sepsis PT CTCAE_v5 Grade 5 Sepsis, CTCAE PT NCI ctcae5:C146539 Death Death Grade 5 Shingles Grade 5 Shingles, CTCAE 10040555 C146539 Grade 5 Shingles Grade 5 Shingles Death NCI Death CTCAE_v5 Grade 5 Shingles PT CTCAE_v5 Grade 5 Shingles, CTCAE PT NCI ctcae5:C146540 Death Death Grade 5 Sinus Disorder, CTCAE Grade 5 Sinus disorder 10062244 C146540 Grade 5 Sinus disorder Grade 5 Sinus disorder Death NCI Death CTCAE_v5 Grade 5 Sinus Disorder, CTCAE PT NCI Grade 5 Sinus disorder PT CTCAE_v5 ctcae5:C146541 Death Death Grade 5 Sinusitis Grade 5 Sinusitis, CTCAE 10040753 C146541 Grade 5 Sinusitis Grade 5 Sinusitis Death NCI Death CTCAE_v5 Grade 5 Sinusitis PT CTCAE_v5 Grade 5 Sinusitis, CTCAE PT NCI ctcae5:C146542 Death Death Grade 5 Sinusoidal Obstruction Syndrome, CTCAE Grade 5 Sinusoidal obstruction syndrome 10063675 C146542 Grade 5 Sinusoidal obstruction syndrome Grade 5 Sinusoidal obstruction syndrome Death NCI Death CTCAE_v5 Grade 5 Sinusoidal Obstruction Syndrome, CTCAE PT NCI Grade 5 Sinusoidal obstruction syndrome PT CTCAE_v5 ctcae5:C146543 Death Death Grade 5 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE Grade 5 Skin and subcutaneous tissue disorders - Other, specify 10040785 C146543 Grade 5 Skin and subcutaneous tissue disorders - Other, specify Grade 5 Skin and subcutaneous tissue disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE PT NCI Grade 5 Skin and subcutaneous tissue disorders - Other, specify PT CTCAE_v5 ctcae5:C146544 Death Death Grade 5 Skin Induration, CTCAE Grade 5 Skin induration 10051837 C146544 Grade 5 Skin induration Grade 5 Skin induration Death NCI Death CTCAE_v5 Grade 5 Skin Induration, CTCAE PT NCI Grade 5 Skin induration PT CTCAE_v5 ctcae5:C146545 Death Death Grade 5 Skin Infection, CTCAE Grade 5 Skin infection 10040872 C146545 Grade 5 Skin infection Grade 5 Skin infection Death NCI Death CTCAE_v5 Grade 5 Skin Infection, CTCAE PT NCI Grade 5 Skin infection PT CTCAE_v5 ctcae5:C146546 Death Death Grade 5 Skin Ulceration, CTCAE Grade 5 Skin ulceration 10040947 C146546 Grade 5 Skin ulceration Grade 5 Skin ulceration Death NCI Death CTCAE_v5 Grade 5 Skin Ulceration, CTCAE PT NCI Grade 5 Skin ulceration PT CTCAE_v5 ctcae5:C146547 Death Death Grade 5 Sleep Apnea, CTCAE Grade 5 Sleep apnea 10040975 C146547 Grade 5 Sleep apnea Grade 5 Sleep apnea Death NCI Death CTCAE_v5 Grade 5 Sleep Apnea, CTCAE PT NCI Grade 5 Sleep apnea PT CTCAE_v5 ctcae5:C146548 Death Death Grade 5 Small Intestinal Anastomotic Leak, CTCAE Grade 5 Small intestinal anastomotic leak 10065892 C146548 Grade 5 Small intestinal anastomotic leak Grade 5 Small intestinal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Small Intestinal Anastomotic Leak, CTCAE PT NCI Grade 5 Small intestinal anastomotic leak PT CTCAE_v5 ctcae5:C146549 Death Death Grade 5 Small Intestinal Mucositis, CTCAE Grade 5 Small intestinal mucositis 10065710 C146549 Grade 5 Small intestinal mucositis Grade 5 Small intestinal mucositis Death NCI Death CTCAE_v5 Grade 5 Small Intestinal Mucositis, CTCAE PT NCI Grade 5 Small intestinal mucositis PT CTCAE_v5 ctcae5:C146550 Death Death Grade 5 Small Intestinal Obstruction, CTCAE Grade 5 Small intestinal obstruction 10041101 C146550 Grade 5 Small intestinal obstruction Grade 5 Small intestinal obstruction Death NCI Death CTCAE_v5 Grade 5 Small Intestinal Obstruction, CTCAE PT NCI Grade 5 Small intestinal obstruction PT CTCAE_v5 ctcae5:C146551 Death Death Grade 5 Small Intestinal Perforation, CTCAE Grade 5 Small intestinal perforation 10041103 C146551 Grade 5 Small intestinal perforation Grade 5 Small intestinal perforation Death NCI Death CTCAE_v5 Grade 5 Small Intestinal Perforation, CTCAE PT NCI Grade 5 Small intestinal perforation PT CTCAE_v5 ctcae5:C146552 Death Death Grade 5 Small Intestinal Stenosis, CTCAE Grade 5 Small intestinal stenosis 10062263 C146552 Grade 5 Small intestinal stenosis Grade 5 Small intestinal stenosis Death NCI Death CTCAE_v5 Grade 5 Small Intestinal Stenosis, CTCAE PT NCI Grade 5 Small intestinal stenosis PT CTCAE_v5 ctcae5:C146553 Death Death Grade 5 Small Intestine Infection, CTCAE Grade 5 Small intestine infection 10065771 C146553 Grade 5 Small intestine infection Grade 5 Small intestine infection Death NCI Death CTCAE_v5 Grade 5 Small Intestine Infection, CTCAE PT NCI Grade 5 Small intestine infection PT CTCAE_v5 ctcae5:C146554 Death Death Grade 5 Small Intestine Ulcer, CTCAE Grade 5 Small intestine ulcer 10041133 C146554 Grade 5 Small intestine ulcer Grade 5 Small intestine ulcer Death NCI Death CTCAE_v5 Grade 5 Small Intestine Ulcer, CTCAE PT NCI Grade 5 Small intestine ulcer PT CTCAE_v5 ctcae5:C146555 Death Death Grade 5 Social Circumstances - Other, Specify, CTCAE Grade 5 Social circumstances - Other, specify 10041244 C146555 Grade 5 Social circumstances - Other, specify Grade 5 Social circumstances - Other, specify Death NCI Death CTCAE_v5 Grade 5 Social Circumstances - Other, Specify, CTCAE PT NCI Grade 5 Social circumstances - Other, specify PT CTCAE_v5 ctcae5:C146556 Death Death Grade 5 Soft Tissue Infection, CTCAE Grade 5 Soft tissue infection 10062255 C146556 Grade 5 Soft tissue infection Grade 5 Soft tissue infection Death NCI Death CTCAE_v5 Grade 5 Soft Tissue Infection, CTCAE PT NCI Grade 5 Soft tissue infection PT CTCAE_v5 ctcae5:C146557 Death Death Grade 5 Soft Tissue Necrosis Lower Limb, CTCAE Grade 5 Soft tissue necrosis lower limb 10065777 C146557 Grade 5 Soft tissue necrosis lower limb Grade 5 Soft tissue necrosis lower limb Death NCI Death CTCAE_v5 Grade 5 Soft Tissue Necrosis Lower Limb, CTCAE PT NCI Grade 5 Soft tissue necrosis lower limb PT CTCAE_v5 ctcae5:C146558 Death Death Grade 5 Soft Tissue Necrosis Upper Limb, CTCAE Grade 5 Soft tissue necrosis upper limb 10065778 C146558 Grade 5 Soft tissue necrosis upper limb Grade 5 Soft tissue necrosis upper limb Death NCI Death CTCAE_v5 Grade 5 Soft Tissue Necrosis Upper Limb, CTCAE PT NCI Grade 5 Soft tissue necrosis upper limb PT CTCAE_v5 ctcae5:C146559 Death Death Grade 5 Somnolence Grade 5 Somnolence, CTCAE 10041349 C146559 Grade 5 Somnolence Grade 5 Somnolence Death NCI Death CTCAE_v5 Grade 5 Somnolence PT CTCAE_v5 Grade 5 Somnolence, CTCAE PT NCI ctcae5:C146560 Death Death Grade 5 Spasticity Grade 5 Spasticity, CTCAE 10041416 C146560 Grade 5 Spasticity Grade 5 Spasticity Death NCI Death CTCAE_v5 Grade 5 Spasticity PT CTCAE_v5 Grade 5 Spasticity, CTCAE PT NCI ctcae5:C146561 Death Death Grade 5 Spermatic Cord Anastomotic Leak, CTCAE Grade 5 Spermatic cord anastomotic leak 10065897 C146561 Grade 5 Spermatic cord anastomotic leak Grade 5 Spermatic cord anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Spermatic Cord Anastomotic Leak, CTCAE PT NCI Grade 5 Spermatic cord anastomotic leak PT CTCAE_v5 ctcae5:C146562 Death Death Grade 5 Spinal Cord Compression, CTCAE Grade 5 Spinal cord compression 10041549 C146562 Grade 5 Spinal cord compression Grade 5 Spinal cord compression Death NCI Death CTCAE_v5 Grade 5 Spinal Cord Compression, CTCAE PT NCI Grade 5 Spinal cord compression PT CTCAE_v5 ctcae5:C146563 Death Death Grade 5 Spinal Fracture, CTCAE Grade 5 Spinal fracture 10041569 C146563 Grade 5 Spinal fracture Grade 5 Spinal fracture Death NCI Death CTCAE_v5 Grade 5 Spinal Fracture, CTCAE PT NCI Grade 5 Spinal fracture PT CTCAE_v5 ctcae5:C146564 Death Death Grade 5 Splenic Infection, CTCAE Grade 5 Splenic infection 10062112 C146564 Grade 5 Splenic infection Grade 5 Splenic infection Death NCI Death CTCAE_v5 Grade 5 Splenic Infection, CTCAE PT NCI Grade 5 Splenic infection PT CTCAE_v5 ctcae5:C146565 Death Death Grade 5 Stenosis of Gastrointestinal Stoma, CTCAE Grade 5 Stenosis of gastrointestinal stoma 10065898 C146565 Grade 5 Stenosis of gastrointestinal stoma Grade 5 Stenosis of gastrointestinal stoma Death NCI Death CTCAE_v5 Grade 5 Stenosis of Gastrointestinal Stoma, CTCAE PT NCI Grade 5 Stenosis of gastrointestinal stoma PT CTCAE_v5 ctcae5:C146566 Death Death Grade 5 Stevens-Johnson Syndrome, CTCAE Grade 5 Stevens-Johnson syndrome 10042033 C146566 Grade 5 Stevens-Johnson syndrome Grade 5 Stevens-Johnson syndrome Death NCI Death CTCAE_v5 Grade 5 Stevens-Johnson Syndrome, CTCAE PT NCI Grade 5 Stevens-Johnson syndrome PT CTCAE_v5 ctcae5:C146567 Death Death Grade 5 Stoma Site Infection, CTCAE Grade 5 Stoma site infection 10064505 C146567 Grade 5 Stoma site infection Grade 5 Stoma site infection Death NCI Death CTCAE_v5 Grade 5 Stoma Site Infection, CTCAE PT NCI Grade 5 Stoma site infection PT CTCAE_v5 ctcae5:C146568 Death Death Grade 5 Stridor Grade 5 Stridor, CTCAE 10042241 C146568 Grade 5 Stridor Grade 5 Stridor Death NCI Death CTCAE_v5 Grade 5 Stridor PT CTCAE_v5 Grade 5 Stridor, CTCAE PT NCI ctcae5:C146569 Death Death Grade 5 Stroke Grade 5 Stroke, CTCAE 10042244 C146569 Grade 5 Stroke Grade 5 Stroke Death NCI Death CTCAE_v5 Grade 5 Stroke PT CTCAE_v5 Grade 5 Stroke, CTCAE PT NCI ctcae5:C146570 Death Death Grade 5 Sudden Death NOS, CTCAE Grade 5 Sudden death NOS 10042435 C146570 Grade 5 Sudden death NOS Grade 5 Sudden death NOS Death NCI Death CTCAE_v5 Grade 5 Sudden Death NOS, CTCAE PT NCI Grade 5 Sudden death NOS PT CTCAE_v5 ctcae5:C146571 Death Death Grade 5 Suicide Attempt, CTCAE Grade 5 Suicide attempt 10042464 C146571 Grade 5 Suicide attempt Grade 5 Suicide attempt Death NCI Death CTCAE_v5 Grade 5 Suicide Attempt, CTCAE PT NCI Grade 5 Suicide attempt PT CTCAE_v5 ctcae5:C146572 Death Death Grade 5 Superficial Soft Tissue Fibrosis, CTCAE Grade 5 Superficial soft tissue fibrosis 10065798 C146572 Grade 5 Superficial soft tissue fibrosis Grade 5 Superficial soft tissue fibrosis Death NCI Death CTCAE_v5 Grade 5 Superficial Soft Tissue Fibrosis, CTCAE PT NCI Grade 5 Superficial soft tissue fibrosis PT CTCAE_v5 ctcae5:C146573 Death Death Grade 5 Superior Vena Cava Syndrome, CTCAE Grade 5 Superior vena cava syndrome 10042569 C146573 Grade 5 Superior vena cava syndrome Grade 5 Superior vena cava syndrome Death NCI Death CTCAE_v5 Grade 5 Superior Vena Cava Syndrome, CTCAE PT NCI Grade 5 Superior vena cava syndrome PT CTCAE_v5 ctcae5:C146574 Death Death Grade 5 Surgical and Medical Procedures - Other, Specify, CTCAE Grade 5 Surgical and medical procedures - Other, specify 10042613 C146574 Grade 5 Surgical and medical procedures - Other, specify Grade 5 Surgical and medical procedures - Other, specify Death NCI Death CTCAE_v5 Grade 5 Surgical and Medical Procedures - Other, Specify, CTCAE PT NCI Grade 5 Surgical and medical procedures - Other, specify PT CTCAE_v5 ctcae5:C146576 Death Death Grade 5 Thromboembolic Event, CTCAE Grade 5 Thromboembolic event 10043565 C146576 Grade 5 Thromboembolic event Grade 5 Thromboembolic event Death NCI Death CTCAE_v5 Grade 5 Thromboembolic Event, CTCAE PT NCI Grade 5 Thromboembolic event PT CTCAE_v5 ctcae5:C146577 Death Death Grade 5 Thrombotic Thrombocytopenic Purpura, CTCAE Grade 5 Thrombotic thrombocytopenic purpura 10043648 C146577 Grade 5 Thrombotic thrombocytopenic purpura Grade 5 Thrombotic thrombocytopenic purpura Death NCI Death CTCAE_v5 Grade 5 Thrombotic Thrombocytopenic Purpura, CTCAE PT NCI Grade 5 Thrombotic thrombocytopenic purpura PT CTCAE_v5 ctcae5:C146578 Death Death Grade 5 Tooth Infection, CTCAE Grade 5 Tooth infection 10048762 C146578 Grade 5 Tooth infection Grade 5 Tooth infection Death NCI Death CTCAE_v5 Grade 5 Tooth Infection, CTCAE PT NCI Grade 5 Tooth infection PT CTCAE_v5 ctcae5:C146579 Death Death Grade 5 Toxic Epidermal Necrolysis, CTCAE Grade 5 Toxic epidermal necrolysis 10044223 C146579 Grade 5 Toxic epidermal necrolysis Grade 5 Toxic epidermal necrolysis Death NCI Death CTCAE_v5 Grade 5 Toxic Epidermal Necrolysis, CTCAE PT NCI Grade 5 Toxic epidermal necrolysis PT CTCAE_v5 ctcae5:C146582 Death Death Grade 5 Tracheal Mucositis, CTCAE Grade 5 Tracheal mucositis 10065900 C146582 Grade 5 Tracheal mucositis Grade 5 Tracheal mucositis Death NCI Death CTCAE_v5 Grade 5 Tracheal Mucositis, CTCAE PT NCI Grade 5 Tracheal mucositis PT CTCAE_v5 ctcae5:C146583 Death Death Grade 5 Tracheal Obstruction, CTCAE Grade 5 Tracheal obstruction 10044291 C146583 Grade 5 Tracheal obstruction Grade 5 Tracheal obstruction Death NCI Death CTCAE_v5 Grade 5 Tracheal Obstruction, CTCAE PT NCI Grade 5 Tracheal obstruction PT CTCAE_v5 ctcae5:C146584 Death Death Grade 5 Tracheal Stenosis, CTCAE Grade 5 Tracheal stenosis 10050816 C146584 Grade 5 Tracheal stenosis Grade 5 Tracheal stenosis Death NCI Death CTCAE_v5 Grade 5 Tracheal Stenosis, CTCAE PT NCI Grade 5 Tracheal stenosis PT CTCAE_v5 ctcae5:C146585 Death Death Grade 5 Tracheitis Grade 5 Tracheitis, CTCAE 10044302 C146585 Grade 5 Tracheitis Grade 5 Tracheitis Death NCI Death CTCAE_v5 Grade 5 Tracheitis PT CTCAE_v5 Grade 5 Tracheitis, CTCAE PT NCI ctcae5:C146586 Death Death Grade 5 Tracheostomy Site Bleeding, CTCAE Grade 5 Tracheostomy site bleeding 10065749 C146586 Grade 5 Tracheostomy site bleeding Grade 5 Tracheostomy site bleeding Death NCI Death CTCAE_v5 Grade 5 Tracheostomy Site Bleeding, CTCAE PT NCI Grade 5 Tracheostomy site bleeding PT CTCAE_v5 ctcae5:C146587 Death Death Grade 5 Treatment Related Secondary Malignancy, CTCAE Grade 5 Treatment related secondary malignancy 10049737 C146587 Grade 5 Treatment related secondary malignancy Grade 5 Treatment related secondary malignancy Death NCI Death CTCAE_v5 Grade 5 Treatment Related Secondary Malignancy, CTCAE PT NCI Grade 5 Treatment related secondary malignancy PT CTCAE_v5 ctcae5:C146588 Death Death Grade 5 Tricuspid Valve Disease, CTCAE Grade 5 Tricuspid valve disease 10061389 C146588 Grade 5 Tricuspid valve disease Grade 5 Tricuspid valve disease Death NCI Death CTCAE_v5 Grade 5 Tricuspid Valve Disease, CTCAE PT NCI Grade 5 Tricuspid valve disease PT CTCAE_v5 ctcae5:C146589 Death Death Grade 5 Tumor Hemorrhage, CTCAE Grade 5 Tumor hemorrhage 10055351 C146589 Grade 5 Tumor hemorrhage Grade 5 Tumor hemorrhage Death NCI Death CTCAE_v5 Grade 5 Tumor Hemorrhage, CTCAE PT NCI Grade 5 Tumor hemorrhage PT CTCAE_v5 ctcae5:C146590 Death Death Grade 5 Upper Gastrointestinal Hemorrhage, CTCAE Grade 5 Upper gastrointestinal hemorrhage 10055356 C146590 Grade 5 Upper gastrointestinal hemorrhage Grade 5 Upper gastrointestinal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Upper Gastrointestinal Hemorrhage, CTCAE PT NCI Grade 5 Upper gastrointestinal hemorrhage PT CTCAE_v5 ctcae5:C146591 Death Death Grade 5 Upper Respiratory Infection, CTCAE Grade 5 Upper respiratory infection 10046300 C146591 Grade 5 Upper respiratory infection Grade 5 Upper respiratory infection Death NCI Death CTCAE_v5 Grade 5 Upper Respiratory Infection, CTCAE PT NCI Grade 5 Upper respiratory infection PT CTCAE_v5 ctcae5:C146592 Death Death Grade 5 Ureteric Anastomotic Leak, CTCAE Grade 5 Ureteric anastomotic leak 10065814 C146592 Grade 5 Ureteric anastomotic leak Grade 5 Ureteric anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Ureteric Anastomotic Leak, CTCAE PT NCI Grade 5 Ureteric anastomotic leak PT CTCAE_v5 ctcae5:C146593 Death Death Grade 5 Urethral Anastomotic Leak, CTCAE Grade 5 Urethral anastomotic leak 10065815 C146593 Grade 5 Urethral anastomotic leak Grade 5 Urethral anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Urethral Anastomotic Leak, CTCAE PT NCI Grade 5 Urethral anastomotic leak PT CTCAE_v5 ctcae5:C146594 Death Death Grade 5 Urethral Infection, CTCAE Grade 5 Urethral infection 10052298 C146594 Grade 5 Urethral infection Grade 5 Urethral infection Death NCI Death CTCAE_v5 Grade 5 Urethral Infection, CTCAE PT NCI Grade 5 Urethral infection PT CTCAE_v5 ctcae5:C146595 Death Death Grade 5 Urinary Fistula, CTCAE Grade 5 Urinary fistula 10065368 C146595 Grade 5 Urinary fistula Grade 5 Urinary fistula Death NCI Death CTCAE_v5 Grade 5 Urinary Fistula, CTCAE PT NCI Grade 5 Urinary fistula PT CTCAE_v5 ctcae5:C146596 Death Death Grade 5 Urinary Tract Infection, CTCAE Grade 5 Urinary tract infection 10046571 C146596 Grade 5 Urinary tract infection Grade 5 Urinary tract infection Death NCI Death CTCAE_v5 Grade 5 Urinary Tract Infection, CTCAE PT NCI Grade 5 Urinary tract infection PT CTCAE_v5 ctcae5:C146597 Death Death Grade 5 Urinary Tract Obstruction, CTCAE Grade 5 Urinary tract obstruction 10061574 C146597 Grade 5 Urinary tract obstruction Grade 5 Urinary tract obstruction Death NCI Death CTCAE_v5 Grade 5 Urinary Tract Obstruction, CTCAE PT NCI Grade 5 Urinary tract obstruction PT CTCAE_v5 ctcae5:C146598 Death Death Grade 5 Urostomy Leak, CTCAE Grade 5 Urostomy leak 10065882 C146598 Grade 5 Urostomy leak Grade 5 Urostomy leak Death NCI Death CTCAE_v5 Grade 5 Urostomy Leak, CTCAE PT NCI Grade 5 Urostomy leak PT CTCAE_v5 ctcae5:C146599 Death Death Grade 5 Urostomy Obstruction, CTCAE Grade 5 Urostomy obstruction 10065883 C146599 Grade 5 Urostomy obstruction Grade 5 Urostomy obstruction Death NCI Death CTCAE_v5 Grade 5 Urostomy Obstruction, CTCAE PT NCI Grade 5 Urostomy obstruction PT CTCAE_v5 ctcae5:C146600 Death Death Grade 5 Urostomy Site Bleeding, CTCAE Grade 5 Urostomy site bleeding 10065748 C146600 Grade 5 Urostomy site bleeding Grade 5 Urostomy site bleeding Death NCI Death CTCAE_v5 Grade 5 Urostomy Site Bleeding, CTCAE PT NCI Grade 5 Urostomy site bleeding PT CTCAE_v5 ctcae5:C146601 Death Death Grade 5 Urostomy Stenosis, CTCAE Grade 5 Urostomy stenosis 10065885 C146601 Grade 5 Urostomy stenosis Grade 5 Urostomy stenosis Death NCI Death CTCAE_v5 Grade 5 Urostomy Stenosis, CTCAE PT NCI Grade 5 Urostomy stenosis PT CTCAE_v5 ctcae5:C146602 Death Death Grade 5 Uterine Anastomotic Leak, CTCAE Grade 5 Uterine anastomotic leak 10065886 C146602 Grade 5 Uterine anastomotic leak Grade 5 Uterine anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Uterine Anastomotic Leak, CTCAE PT NCI Grade 5 Uterine anastomotic leak PT CTCAE_v5 ctcae5:C146603 Death Death Grade 5 Uterine Fistula, CTCAE Grade 5 Uterine fistula 10065811 C146603 Grade 5 Uterine fistula Grade 5 Uterine fistula Death NCI Death CTCAE_v5 Grade 5 Uterine Fistula, CTCAE PT NCI Grade 5 Uterine fistula PT CTCAE_v5 ctcae5:C146605 Death Death Grade 5 Uterine Infection, CTCAE Grade 5 Uterine infection 10062233 C146605 Grade 5 Uterine infection Grade 5 Uterine infection Death NCI Death CTCAE_v5 Grade 5 Uterine Infection, CTCAE PT NCI Grade 5 Uterine infection PT CTCAE_v5 ctcae5:C146606 Death Death Grade 5 Uterine Perforation, CTCAE Grade 5 Uterine perforation 10046810 C146606 Grade 5 Uterine perforation Grade 5 Uterine perforation Death NCI Death CTCAE_v5 Grade 5 Uterine Perforation, CTCAE PT NCI Grade 5 Uterine perforation PT CTCAE_v5 ctcae5:C146607 Death Death Grade 5 Vaginal Anastomotic Leak, CTCAE Grade 5 Vaginal anastomotic leak 10065887 C146607 Grade 5 Vaginal anastomotic leak Grade 5 Vaginal anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Vaginal Anastomotic Leak, CTCAE PT NCI Grade 5 Vaginal anastomotic leak PT CTCAE_v5 ctcae5:C146610 Death Death Grade 5 Vaginal Infection, CTCAE Grade 5 Vaginal infection 10046914 C146610 Grade 5 Vaginal infection Grade 5 Vaginal infection Death NCI Death CTCAE_v5 Grade 5 Vaginal Infection, CTCAE PT NCI Grade 5 Vaginal infection PT CTCAE_v5 ctcae5:C146611 Death Death Grade 5 Vaginal Perforation, CTCAE Grade 5 Vaginal perforation 10065818 C146611 Grade 5 Vaginal perforation Grade 5 Vaginal perforation Death NCI Death CTCAE_v5 Grade 5 Vaginal Perforation, CTCAE PT NCI Grade 5 Vaginal perforation PT CTCAE_v5 ctcae5:C146612 Death Death Grade 5 Vaginal Stricture, CTCAE Grade 5 Vaginal stricture 10053496 C146612 Grade 5 Vaginal stricture Grade 5 Vaginal stricture Death NCI Death CTCAE_v5 Grade 5 Vaginal Stricture, CTCAE PT NCI Grade 5 Vaginal stricture PT CTCAE_v5 ctcae5:C146613 Death Death Grade 5 Vagus Nerve Disorder, CTCAE Grade 5 Vagus nerve disorder 10061403 C146613 Grade 5 Vagus nerve disorder Grade 5 Vagus nerve disorder Death NCI Death CTCAE_v5 Grade 5 Vagus Nerve Disorder, CTCAE PT NCI Grade 5 Vagus nerve disorder PT CTCAE_v5 ctcae5:C146614 Death Death Grade 5 Vas Deferens Anastomotic Leak, CTCAE Grade 5 Vas deferens anastomotic leak 10065888 C146614 Grade 5 Vas deferens anastomotic leak Grade 5 Vas deferens anastomotic leak Death NCI Death CTCAE_v5 Grade 5 Vas Deferens Anastomotic Leak, CTCAE PT NCI Grade 5 Vas deferens anastomotic leak PT CTCAE_v5 ctcae5:C146615 Death Death Grade 5 Vascular Access Complication, CTCAE Grade 5 Vascular access complication 10062169 C146615 Grade 5 Vascular access complication Grade 5 Vascular access complication Death NCI Death CTCAE_v5 Grade 5 Vascular Access Complication, CTCAE PT NCI Grade 5 Vascular access complication PT CTCAE_v5 ctcae5:C146616 Death Death Grade 5 Vascular Disorders - Other, Specify, CTCAE Grade 5 Vascular disorders - Other, specify 10047065 C146616 Grade 5 Vascular disorders - Other, specify Grade 5 Vascular disorders - Other, specify Death NCI Death CTCAE_v5 Grade 5 Vascular Disorders - Other, Specify, CTCAE PT NCI Grade 5 Vascular disorders - Other, specify PT CTCAE_v5 ctcae5:C146617 Death Death Grade 5 Vasovagal Reaction, CTCAE Grade 5 Vasovagal reaction 10047166 C146617 Grade 5 Vasovagal reaction Grade 5 Vasovagal reaction Death NCI Death CTCAE_v5 Grade 5 Vasovagal Reaction, CTCAE PT NCI Grade 5 Vasovagal reaction PT CTCAE_v5 ctcae5:C146618 Death Death Grade 5 Venous Injury, CTCAE Grade 5 Venous injury 10047228 C146618 Grade 5 Venous injury Grade 5 Venous injury Death NCI Death CTCAE_v5 Grade 5 Venous Injury, CTCAE PT NCI Grade 5 Venous injury PT CTCAE_v5 ctcae5:C146619 Death Death Grade 5 Ventricular Arrhythmia, CTCAE Grade 5 Ventricular arrhythmia 10047281 C146619 Grade 5 Ventricular arrhythmia Grade 5 Ventricular arrhythmia Death NCI Death CTCAE_v5 Grade 5 Ventricular Arrhythmia, CTCAE PT NCI Grade 5 Ventricular arrhythmia PT CTCAE_v5 ctcae5:C146620 Death Death Grade 5 Visceral Arterial Ischemia, CTCAE Grade 5 Visceral arterial ischemia 10054692 C146620 Grade 5 Visceral arterial ischemia Grade 5 Visceral arterial ischemia Death NCI Death CTCAE_v5 Grade 5 Visceral Arterial Ischemia, CTCAE PT NCI Grade 5 Visceral arterial ischemia PT CTCAE_v5 ctcae5:C146621 Death Death Grade 5 Vulval Infection, CTCAE Grade 5 Vulval infection 10065772 C146621 Grade 5 Vulval infection Grade 5 Vulval infection Death NCI Death CTCAE_v5 Grade 5 Vulval Infection, CTCAE PT NCI Grade 5 Vulval infection PT CTCAE_v5 ctcae5:C146622 Death Death Grade 5 Wheezing Grade 5 Wheezing, CTCAE 10047924 C146622 Grade 5 Wheezing Grade 5 Wheezing Death NCI Death CTCAE_v5 Grade 5 Wheezing PT CTCAE_v5 Grade 5 Wheezing, CTCAE PT NCI ctcae5:C146623 Death Death Grade 5 Wound Complication, CTCAE Grade 5 Wound complication 10053692 C146623 Grade 5 Wound complication Grade 5 Wound complication Death NCI Death CTCAE_v5 Grade 5 Wound Complication, CTCAE PT NCI Grade 5 Wound complication PT CTCAE_v5 ctcae5:C146624 Death Death Grade 5 Wound Dehiscence, CTCAE Grade 5 Wound dehiscence 10048031 C146624 Grade 5 Wound dehiscence Grade 5 Wound dehiscence Death NCI Death CTCAE_v5 Grade 5 Wound Dehiscence, CTCAE PT NCI Grade 5 Wound dehiscence PT CTCAE_v5 ctcae5:C146625 Death Death Grade 5 Wound Infection, CTCAE Grade 5 Wound infection 10048038 C146625 Grade 5 Wound infection Grade 5 Wound infection Death NCI Death CTCAE_v5 Grade 5 Wound Infection, CTCAE PT NCI Grade 5 Wound infection PT CTCAE_v5 ctcae5:C146626 A disorder characterized by a sensation of marked discomfort in the gingival region. A disorder characterized by a sensation of marked discomfort in the gingival region. Gingival Pain, CTCAE Gingival pain 10018286 C146626 Gingival pain Gingival pain A disorder characterized by a sensation of marked discomfort in the gingival region. NCI A disorder characterized by a sensation of marked discomfort in the gingival region. CTCAE_v5 Gingival Pain, CTCAE PT NCI Gingival pain PT CTCAE_v5 ctcae5:C146627 A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. Oral Pain, CTCAE 5.0 Oral pain 10031009 C146627 Oral pain Oral pain A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. NCI A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips. CTCAE_v5 Oral Pain, CTCAE 5.0 PT NCI Oral pain PT CTCAE_v5 ctcae5:C146629 A disorder characterized by a dysrhythmia that originates in the ventricles. A disorder characterized by a dysrhythmia that originates in the ventricles. Ventricular Arrhythmia, CTCAE 5.0 Ventricular arrhythmia 10047281 C146629 Ventricular arrhythmia Ventricular arrhythmia A disorder characterized by a dysrhythmia that originates in the ventricles. NCI A disorder characterized by a dysrhythmia that originates in the ventricles. CTCAE_v5 Ventricular Arrhythmia, CTCAE 5.0 PT NCI Ventricular arrhythmia PT CTCAE_v5 ctcae5:C146630 Gastrointestinal Disorders Gastrointestinal Disorders, CTCAE C146630 Gastrointestinal Disorders Gastrointestinal Disorders Gastrointestinal Disorders PT NCI Gastrointestinal Disorders, CTCAE PT NCI ctcae5:C146631 A disorder characterized by a sensation of marked discomfort in the rectal region. A disorder characterized by a sensation of marked discomfort in the rectal region. Rectal Pain, CTCAE 5.0 Rectal pain 10038072 C146631 Rectal pain Rectal pain A disorder characterized by a sensation of marked discomfort in the rectal region. NCI A disorder characterized by a sensation of marked discomfort in the rectal region. CTCAE_v5 Rectal Pain, CTCAE 5.0 PT NCI Rectal pain PT CTCAE_v5 ctcae5:C146632 A disorder characterized by bleeding from the retroperitoneal area. A disorder characterized by bleeding from the retroperitoneal area. Retroperitoneal Hemorrhage, CTCAE 5.0 Retroperitoneal hemorrhage 10038981 C146632 Retroperitoneal hemorrhage Retroperitoneal hemorrhage A disorder characterized by bleeding from the retroperitoneal area. NCI A disorder characterized by bleeding from the retroperitoneal area. CTCAE_v5 Retroperitoneal Hemorrhage, CTCAE 5.0 PT NCI Retroperitoneal hemorrhage PT CTCAE_v5 ctcae5:C146633 A disorder characterized by a rupture in the ileal wall. A disorder characterized by a rupture in the ileal wall. Ileal Perforation, CTCAE 5.0 Ileal perforation 10021305 C146633 Ileal perforation Ileal perforation A disorder characterized by a rupture in the ileal wall. NCI A disorder characterized by a rupture in the ileal wall. CTCAE_v5 Ileal Perforation, CTCAE 5.0 PT NCI Ileal perforation PT CTCAE_v5 ctcae5:C146634 A disorder characterized by a rupture in the rectal wall. A disorder characterized by a rupture in the rectal wall. Rectal Perforation, CTCAE 5.0 Rectal perforation 10038073 C146634 Rectal perforation Rectal perforation A disorder characterized by a rupture in the rectal wall. NCI A disorder characterized by a rupture in the rectal wall. CTCAE_v5 Rectal Perforation, CTCAE 5.0 PT NCI Rectal perforation PT CTCAE_v5 ctcae5:C146635 A disorder characterized by a rupture in the small intestine wall. A disorder characterized by a rupture in the small intestine wall. Small Intestinal Perforation, CTCAE 5.0 Small intestinal perforation 10041103 C146635 Small intestinal perforation Small intestinal perforation A disorder characterized by a rupture in the small intestine wall. NCI A disorder characterized by a rupture in the small intestine wall. CTCAE_v5 Small Intestinal Perforation, CTCAE 5.0 PT NCI Small intestinal perforation PT CTCAE_v5 ctcae5:C146637 A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. Gastrointestinal Fistula, CTCAE 5.0 Gastrointestinal fistula 10017877 C146637 Gastrointestinal fistula Gastrointestinal fistula A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between any part of the gastrointestinal system and another organ or anatomic site. CTCAE_v5 Gastrointestinal Fistula, CTCAE 5.0 PT NCI Gastrointestinal fistula PT CTCAE_v5 ctcae5:C146642 A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. Serum Sickness, CTCAE 5.0 Serum sickness 10040400 C146642 Serum sickness Serum sickness A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. NCI A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. CTCAE_v5 Serum Sickness, CTCAE 5.0 PT NCI Serum sickness PT CTCAE_v5 ctcae5:C146643 A disorder characterized by episodic reddening of the skin, especially face, neck, or chest. A disorder characterized by episodic reddening of the skin, especially face, neck, or chest. Flushing Flushing, CTCAE 5.0 10016825 C146643 Flushing Flushing A disorder characterized by episodic reddening of the skin, especially face, neck, or chest. NCI A disorder characterized by episodic reddening of the skin, especially face, neck, or chest. CTCAE_v5 Flushing PT CTCAE_v5 Flushing, CTCAE 5.0 PT NCI ctcae5:C146644 A disorder characterized by the degeneration and thinning of the epidermis and dermis. A disorder characterized by the degeneration and thinning of the epidermis and dermis. Skin Atrophy, CTCAE 5.0 Skin atrophy 10040799 C146644 Skin atrophy Skin atrophy A disorder characterized by the degeneration and thinning of the epidermis and dermis. NCI A disorder characterized by the degeneration and thinning of the epidermis and dermis. CTCAE_v5 Skin Atrophy, CTCAE 5.0 PT NCI Skin atrophy PT CTCAE_v5 ctcae5:C146645 A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. Precocious Puberty, CTCAE 5.0 Precocious puberty 10058084 C146645 Precocious puberty Precocious puberty A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. NCI A disorder characterized by unusually early development of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys. CTCAE_v5 Precocious Puberty, CTCAE 5.0 PT NCI Precocious puberty PT CTCAE_v5 ctcae5:C146663 A disorder characterized by a sensation of marked discomfort in the pleura. A disorder characterized by a sensation of marked discomfort in the pleura. Pleuritic Pain, CTCAE 5.0 Pleuritic pain 10035623 C146663 Pleuritic pain Pleuritic pain A disorder characterized by a sensation of marked discomfort in the pleura. NCI A disorder characterized by a sensation of marked discomfort in the pleura. CTCAE_v5 Pleuritic Pain, CTCAE 5.0 PT NCI Pleuritic pain PT CTCAE_v5 ctcae5:C146664 A disorder characterized by a sensation of marked discomfort in the prostate gland. A disorder characterized by a sensation of marked discomfort in the prostate gland. Prostatic Pain, CTCAE 5.0 Prostatic pain 10036968 C146664 Prostatic pain Prostatic pain A disorder characterized by a sensation of marked discomfort in the prostate gland. NCI A disorder characterized by a sensation of marked discomfort in the prostate gland. CTCAE_v5 Prostatic Pain, CTCAE 5.0 PT NCI Prostatic pain PT CTCAE_v5 ctcae5:C146665 A disorder characterized by a sensation of marked discomfort in the scrotal area. A disorder characterized by a sensation of marked discomfort in the scrotal area. Scrotal Pain, CTCAE 5.0 Scrotal pain 10039757 C146665 Scrotal pain Scrotal pain A disorder characterized by a sensation of marked discomfort in the scrotal area. NCI A disorder characterized by a sensation of marked discomfort in the scrotal area. CTCAE_v5 Scrotal Pain, CTCAE 5.0 PT NCI Scrotal pain PT CTCAE_v5 ctcae5:C146666 A disorder characterized by a sensation of marked discomfort in the testis. A disorder characterized by a sensation of marked discomfort in the testis. Testicular Pain, CTCAE 5.0 Testicular pain 10043345 C146666 Testicular pain Testicular pain A disorder characterized by a sensation of marked discomfort in the testis. NCI A disorder characterized by a sensation of marked discomfort in the testis. CTCAE_v5 Testicular Pain, CTCAE 5.0 PT NCI Testicular pain PT CTCAE_v5 ctcae5:C146674 A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. Cataract Cataract, CTCAE 5.0 10007739 C146674 Cataract Cataract A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. NCI A disorder characterized by partial or complete opacity of the crystalline lens of one or both eyes. This results in a decrease in visual acuity and eventual blindness if untreated. CTCAE_v5 Cataract PT CTCAE_v5 Cataract, CTCAE 5.0 PT NCI ctcae5:C146677 A disorder characterized by bleeding into the vitreous humor. A disorder characterized by bleeding into the vitreous humor. Vitreous Hemorrhage, CTCAE 5.0 Vitreous hemorrhage 10047656 C146677 Vitreous hemorrhage Vitreous hemorrhage A disorder characterized by bleeding into the vitreous humor. NCI A disorder characterized by bleeding into the vitreous humor. CTCAE_v5 Vitreous Hemorrhage, CTCAE 5.0 PT NCI Vitreous hemorrhage PT CTCAE_v5 ctcae5:C146679 A disorder characterized by a sensation of marked discomfort in the pelvis. A disorder characterized by a sensation of marked discomfort in the pelvis. Pelvic Pain, CTCAE 5.0 Pelvic pain 10034263 C146679 Pelvic pain Pelvic pain A disorder characterized by a sensation of marked discomfort in the pelvis. NCI A disorder characterized by a sensation of marked discomfort in the pelvis. CTCAE_v5 Pelvic Pain, CTCAE 5.0 PT NCI Pelvic pain PT CTCAE_v5 ctcae5:C146680 A disorder characterized by a sensation of marked discomfort in the penis. A disorder characterized by a sensation of marked discomfort in the penis. Penile Pain, CTCAE 5.0 Penile pain 10034310 C146680 Penile pain Penile pain A disorder characterized by a sensation of marked discomfort in the penis. NCI A disorder characterized by a sensation of marked discomfort in the penis. CTCAE_v5 Penile Pain, CTCAE 5.0 PT NCI Penile pain PT CTCAE_v5 ctcae5:C146681 A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. Perineal Pain, CTCAE 5.0 Perineal pain 10061339 C146681 Perineal pain Perineal pain A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. NCI A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the anus. CTCAE_v5 Perineal Pain, CTCAE 5.0 PT NCI Perineal pain PT CTCAE_v5 ctcae5:C146682 A disorder characterized by a sensation of marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. A disorder characterized by a sensation of marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. Phantom Pain, CTCAE 5.0 Phantom pain 10056238 C146682 Phantom pain Phantom pain A disorder characterized by a sensation of marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. NCI A disorder characterized by a sensation of marked discomfort related to a limb or an organ that is removed from or is not physically part of the body. CTCAE_v5 Phantom Pain, CTCAE 5.0 PT NCI Phantom pain PT CTCAE_v5 ctcae5:C146683 A disorder characterized by a sensation of marked discomfort in the uterus. A disorder characterized by a sensation of marked discomfort in the uterus. Uterine Pain, CTCAE 5.0 Uterine pain 10046809 C146683 Uterine pain Uterine pain A disorder characterized by a sensation of marked discomfort in the uterus. NCI A disorder characterized by a sensation of marked discomfort in the uterus. CTCAE_v5 Uterine Pain, CTCAE 5.0 PT NCI Uterine pain PT CTCAE_v5 ctcae5:C146684 A disorder characterized by a sensation of marked discomfort in the vagina. A disorder characterized by a sensation of marked discomfort in the vagina. Vaginal Pain, CTCAE 5.0 Vaginal pain 10046937 C146684 Vaginal pain Vaginal pain A disorder characterized by a sensation of marked discomfort in the vagina. NCI A disorder characterized by a sensation of marked discomfort in the vagina. CTCAE_v5 Vaginal Pain, CTCAE 5.0 PT NCI Vaginal pain PT CTCAE_v5 ctcae5:C146685 A disorder characterized by excessive development of the breasts in males. A disorder characterized by excessive development of the breasts in males. Gynecomastia Gynecomastia, CTCAE 5.0 10018801 C146685 Gynecomastia Gynecomastia A disorder characterized by excessive development of the breasts in males. NCI A disorder characterized by excessive development of the breasts in males. CTCAE_v5 Gynecomastia PT CTCAE_v5 Gynecomastia, CTCAE 5.0 PT NCI ctcae5:C146687 A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. Vaginal Dryness, CTCAE 5.0 Vaginal dryness 10046904 C146687 Vaginal dryness Vaginal dryness A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. NCI A disorder characterized by an uncomfortable feeling of itching and burning in the vagina. CTCAE_v5 Vaginal Dryness, CTCAE 5.0 PT NCI Vaginal dryness PT CTCAE_v5 ctcae5:C146688 A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. Tumor Lysis Syndrome, CTCAE 5.0 Tumor lysis syndrome 10045152 C146688 Tumor lysis syndrome Tumor lysis syndrome A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. NCI A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. CTCAE_v5 Tumor Lysis Syndrome, CTCAE 5.0 PT NCI Tumor lysis syndrome PT CTCAE_v5 ctcae5:C146690 A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. Tinnitus Tinnitus, CTCAE 5.0 10043882 C146690 Tinnitus Tinnitus A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. NCI A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. CTCAE_v5 Tinnitus PT CTCAE_v5 Tinnitus, CTCAE 5.0 PT NCI ctcae5:C146694 A disorder characterized by a circumscribed, erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. A disorder characterized by a circumscribed, erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. Stomal Ulcer, CTCAE 5.0 Stomal ulcer 10042127 C146694 Stomal ulcer Stomal ulcer A disorder characterized by a circumscribed, erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. NCI A disorder characterized by a circumscribed, erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure. CTCAE_v5 Stomal Ulcer, CTCAE 5.0 PT NCI Stomal ulcer PT CTCAE_v5 ctcae5:C146695 A disorder characterized by inflammation of the muscle tissue of the heart. A disorder characterized by inflammation of the muscle tissue of the heart. Myocarditis Myocarditis, CTCAE 5.0 10028606 C146695 Myocarditis Myocarditis A disorder characterized by inflammation of the muscle tissue of the heart. NCI A disorder characterized by inflammation of the muscle tissue of the heart. CTCAE_v5 Myocarditis PT CTCAE_v5 Myocarditis, CTCAE 5.0 PT NCI ctcae5:C146696 A disorder characterized by blockage of vaginal canal. A disorder characterized by blockage of vaginal canal. Vaginal Obstruction, CTCAE 5.0 Vaginal obstruction 10065817 C146696 Vaginal obstruction Vaginal obstruction A disorder characterized by blockage of vaginal canal. NCI A disorder characterized by blockage of vaginal canal. CTCAE_v5 Vaginal Obstruction, CTCAE 5.0 PT NCI Vaginal obstruction PT CTCAE_v5 ctcae5:C146697 A disorder characterized by a rupture in the vaginal wall. A disorder characterized by a rupture in the vaginal wall. Vaginal Perforation, CTCAE 5.0 Vaginal perforation 10065818 C146697 Vaginal perforation Vaginal perforation A disorder characterized by a rupture in the vaginal wall. NCI A disorder characterized by a rupture in the vaginal wall. CTCAE_v5 Vaginal Perforation, CTCAE 5.0 PT NCI Vaginal perforation PT CTCAE_v5 ctcae5:C146698 A disorder characterized by a sudden and involuntary contraction of the bladder wall. A disorder characterized by a sudden and involuntary contraction of the bladder wall. Bladder Spasm, CTCAE 5.0 Bladder spasm 10048994 C146698 Bladder spasm Bladder spasm A disorder characterized by a sudden and involuntary contraction of the bladder wall. NCI A disorder characterized by a sudden and involuntary contraction of the bladder wall. CTCAE_v5 Bladder Spasm, CTCAE 5.0 PT NCI Bladder spasm PT CTCAE_v5 ctcae5:C146699 A disorder characterized by a pathologic process involving the brain. A disorder characterized by a pathologic process involving the brain. Encephalopathy Encephalopathy, CTCAE 5.0 10014625 C146699 Encephalopathy Encephalopathy A disorder characterized by a pathologic process involving the brain. NCI A disorder characterized by a pathologic process involving the brain. CTCAE_v5 Encephalopathy PT CTCAE_v5 Encephalopathy, CTCAE 5.0 PT NCI ctcae5:C146700 A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. Seizure Seizure, CTCAE 5.0 10039906 C146700 Seizure Seizure A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. NCI A disorder characterized by a sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. CTCAE_v5 Seizure PT CTCAE_v5 Seizure, CTCAE 5.0 PT NCI ctcae5:C146707 A disorder characterized by a rupture in the bladder wall. A disorder characterized by a rupture in the bladder wall. Bladder Perforation, CTCAE 5.0 Bladder perforation 10063575 C146707 Bladder perforation Bladder perforation A disorder characterized by a rupture in the bladder wall. NCI A disorder characterized by a rupture in the bladder wall. CTCAE_v5 Bladder Perforation, CTCAE 5.0 PT NCI Bladder perforation PT CTCAE_v5 ctcae5:C146708 A disorder characterized by a rupture in the gallbladder wall. A disorder characterized by a rupture in the gallbladder wall. Gallbladder Perforation, CTCAE 5.0 Gallbladder perforation 10017639 C146708 Gallbladder perforation Gallbladder perforation A disorder characterized by a rupture in the gallbladder wall. NCI A disorder characterized by a rupture in the gallbladder wall. CTCAE_v5 Gallbladder Perforation, CTCAE 5.0 PT NCI Gallbladder perforation PT CTCAE_v5 ctcae5:C146710 A disorder characterized by bleeding from esophageal varices. A disorder characterized by bleeding from esophageal varices. Esophageal Varices Hemorrhage, CTCAE 5.0 Esophageal varices hemorrhage 10015453 C146710 Esophageal varices hemorrhage Esophageal varices hemorrhage A disorder characterized by bleeding from esophageal varices. NCI A disorder characterized by bleeding from esophageal varices. CTCAE_v5 Esophageal Varices Hemorrhage, CTCAE 5.0 PT NCI Esophageal varices hemorrhage PT CTCAE_v5 ctcae5:C146714 A disorder characterized by a rupture of the fallopian tube wall. A disorder characterized by a rupture of the fallopian tube wall. Fallopian Tube Perforation, CTCAE 5.0 Fallopian tube perforation 10065790 C146714 Fallopian tube perforation Fallopian tube perforation A disorder characterized by a rupture of the fallopian tube wall. NCI A disorder characterized by a rupture of the fallopian tube wall. CTCAE_v5 Fallopian Tube Perforation, CTCAE 5.0 PT NCI Fallopian tube perforation PT CTCAE_v5 ctcae5:C146719 A disorder characterized by failure of the left ventricle to produce adequate output. A disorder characterized by failure of the left ventricle to produce adequate output. Left Ventricular Systolic Dysfunction, CTCAE 5.0 Left ventricular systolic dysfunction 10069501 C146719 Left ventricular systolic dysfunction Left ventricular systolic dysfunction A disorder characterized by failure of the left ventricle to produce adequate output. NCI A disorder characterized by failure of the left ventricle to produce adequate output. CTCAE_v5 Left Ventricular Systolic Dysfunction, CTCAE 5.0 PT NCI Left ventricular systolic dysfunction PT CTCAE_v5 ctcae5:C146729 A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. Retinal Detachment, CTCAE 5.0 Retinal detachment 10038848 C146729 Retinal detachment Retinal detachment A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. NCI A disorder characterized by the separation of the inner retina layers from the underlying pigment epithelium. CTCAE_v5 Retinal Detachment, CTCAE 5.0 PT NCI Retinal detachment PT CTCAE_v5 ctcae5:C146730 A disorder characterized by necrotizing enterocolitis in neutropenic patients. A disorder characterized by necrotizing enterocolitis in neutropenic patients. Typhlitis Typhlitis, CTCAE 5.0 10045271 C146730 Typhlitis Typhlitis A disorder characterized by necrotizing enterocolitis in neutropenic patients. NCI A disorder characterized by necrotizing enterocolitis in neutropenic patients. CTCAE_v5 Typhlitis PT CTCAE_v5 Typhlitis, CTCAE 5.0 PT NCI ctcae5:C146731 A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. Asystole Asystole, CTCAE 5.0 10003586 C146731 Asystole Asystole A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. NCI A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart. CTCAE_v5 Asystole PT CTCAE_v5 Asystole, CTCAE 5.0 PT NCI ctcae5:C146732 A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. Ventricular Fibrillation, CTCAE 5.0 Ventricular fibrillation 10047290 C146732 Ventricular fibrillation Ventricular fibrillation A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. NCI A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. CTCAE_v5 Ventricular Fibrillation, CTCAE 5.0 PT NCI Ventricular fibrillation PT CTCAE_v5 ctcae5:C146733 A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. Ventricular Tachycardia, CTCAE 5.0 Ventricular tachycardia 10047302 C146733 Ventricular tachycardia Ventricular tachycardia A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. NCI A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates distal to the bundle of His. CTCAE_v5 Ventricular Tachycardia, CTCAE 5.0 PT NCI Ventricular tachycardia PT CTCAE_v5 ctcae5:C146735 A disorder characterized by a necrotic process occurring in the gallbladder. A disorder characterized by a necrotic process occurring in the gallbladder. Gallbladder Necrosis, CTCAE 5.0 Gallbladder necrosis 10059446 C146735 Gallbladder necrosis Gallbladder necrosis A disorder characterized by a necrotic process occurring in the gallbladder. NCI A disorder characterized by a necrotic process occurring in the gallbladder. CTCAE_v5 Gallbladder Necrosis, CTCAE 5.0 PT NCI Gallbladder necrosis PT CTCAE_v5 ctcae5:C146736 A disorder characterized by a necrotic process occurring in the hepatic parenchyma. A disorder characterized by a necrotic process occurring in the hepatic parenchyma. Hepatic Necrosis, CTCAE 5.0 Hepatic necrosis 10019692 C146736 Hepatic necrosis Hepatic necrosis A disorder characterized by a necrotic process occurring in the hepatic parenchyma. NCI A disorder characterized by a necrotic process occurring in the hepatic parenchyma. CTCAE_v5 Hepatic Necrosis, CTCAE 5.0 PT NCI Hepatic necrosis PT CTCAE_v5 ctcae5:C146737 A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. Ataxia Ataxia, CTCAE 5.0 10003591 C146737 Ataxia Ataxia A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. NCI A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability to perform voluntary activities. CTCAE_v5 Ataxia PT CTCAE_v5 Ataxia, CTCAE 5.0 PT NCI ctcae5:C146738 A disorder characterized by the presence of dilated veins in the rectum and surrounding area. A disorder characterized by the presence of dilated veins in the rectum and surrounding area. Hemorrhoids Hemorrhoids, CTCAE 5.0 10019611 C146738 Hemorrhoids Hemorrhoids A disorder characterized by the presence of dilated veins in the rectum and surrounding area. NCI A disorder characterized by the presence of dilated veins in the rectum and surrounding area. CTCAE_v5 Hemorrhoids PT CTCAE_v5 Hemorrhoids, CTCAE 5.0 PT NCI ctcae5:C146739 A disorder characterized by a sensation of marked discomfort in the back region. A disorder characterized by a sensation of marked discomfort in the back region. Back Pain, CTCAE 5.0 Back pain 10003988 C146739 Back pain Back pain A disorder characterized by a sensation of marked discomfort in the back region. NCI A disorder characterized by a sensation of marked discomfort in the back region. CTCAE_v5 Back Pain, CTCAE 5.0 PT NCI Back pain PT CTCAE_v5 ctcae5:C146740 A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. Telangiectasia Telangiectasia, CTCAE 5.0 10043189 C146740 Telangiectasia Telangiectasia A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. NCI A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes. CTCAE_v5 Telangiectasia PT CTCAE_v5 Telangiectasia, CTCAE 5.0 PT NCI ctcae5:C146741 A disorder characterized by a sensation of marked discomfort in the bones. A disorder characterized by a sensation of marked discomfort in the bones. Bone Pain, CTCAE 5.0 Bone pain 10006002 C146741 Bone pain Bone pain A disorder characterized by a sensation of marked discomfort in the bones. NCI A disorder characterized by a sensation of marked discomfort in the bones. CTCAE_v5 Bone Pain, CTCAE 5.0 PT NCI Bone pain PT CTCAE_v5 ctcae5:C146742 A disorder characterized by a sensation of marked discomfort in the breast region. A disorder characterized by a sensation of marked discomfort in the breast region. Breast Pain, CTCAE 5.0 Breast pain 10006298 C146742 Breast pain Breast pain A disorder characterized by a sensation of marked discomfort in the breast region. NCI A disorder characterized by a sensation of marked discomfort in the breast region. CTCAE_v5 Breast Pain, CTCAE 5.0 PT NCI Breast pain PT CTCAE_v5 ctcae5:C146743 A disorder characterized by a sensation of marked discomfort in the chest wall. A disorder characterized by a sensation of marked discomfort in the chest wall. Chest Wall Pain, CTCAE 5.0 Chest wall pain 10008496 C146743 Chest wall pain Chest wall pain A disorder characterized by a sensation of marked discomfort in the chest wall. NCI A disorder characterized by a sensation of marked discomfort in the chest wall. CTCAE_v5 Chest Wall Pain, CTCAE 5.0 PT NCI Chest wall pain PT CTCAE_v5 ctcae5:C146744 A disorder characterized by a sensation of marked discomfort in the buttocks. A disorder characterized by a sensation of marked discomfort in the buttocks. Buttock Pain, CTCAE 5.0 Buttock pain 10048677 C146744 Buttock pain Buttock pain A disorder characterized by a sensation of marked discomfort in the buttocks. NCI A disorder characterized by a sensation of marked discomfort in the buttocks. CTCAE_v5 Buttock Pain, CTCAE 5.0 PT NCI Buttock pain PT CTCAE_v5 ctcae5:C146745 A disorder characterized by a sensation of marked discomfort in the external ear region. A disorder characterized by a sensation of marked discomfort in the external ear region. External Ear Pain, CTCAE 5.0 External ear pain 10065785 C146745 External ear pain External ear pain A disorder characterized by a sensation of marked discomfort in the external ear region. NCI A disorder characterized by a sensation of marked discomfort in the external ear region. CTCAE_v5 External Ear Pain, CTCAE 5.0 PT NCI External ear pain PT CTCAE_v5 ctcae5:C146746 A disorder characterized by a conspicuous change in cognitive function. A disorder characterized by a conspicuous change in cognitive function. Cognitive Disturbance, CTCAE 5.0 Cognitive disturbance 10009845 C146746 Cognitive disturbance Cognitive disturbance A disorder characterized by a conspicuous change in cognitive function. NCI A disorder characterized by a conspicuous change in cognitive function. CTCAE_v5 Cognitive Disturbance, CTCAE 5.0 PT NCI Cognitive disturbance PT CTCAE_v5 ctcae5:C146747 A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. Dizziness Dizziness, CTCAE 5.0 10013573 C146747 Dizziness Dizziness A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. NCI A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rocking. CTCAE_v5 Dizziness PT CTCAE_v5 Dizziness, CTCAE 5.0 PT NCI ctcae5:C146748 A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. Euphoria Euphoria, CTCAE 5.0 10015533 C146748 Euphoria Euphoria A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. NCI A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimuli. CTCAE_v5 Euphoria PT CTCAE_v5 Euphoria, CTCAE 5.0 PT NCI ctcae5:C146749 A disorder characterized by non-neoplastic overgrowth of bone. A disorder characterized by non-neoplastic overgrowth of bone. Exostosis Exostosis, CTCAE 5.0 10015688 C146749 Exostosis Exostosis A disorder characterized by non-neoplastic overgrowth of bone. NCI A disorder characterized by non-neoplastic overgrowth of bone. CTCAE_v5 Exostosis PT CTCAE_v5 Exostosis, CTCAE 5.0 PT NCI ctcae5:C146750 A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. Syncope Syncope, CTCAE 5.0 10042772 C146750 Syncope Syncope A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. NCI A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain. CTCAE_v5 Syncope PT CTCAE_v5 Syncope, CTCAE 5.0 PT NCI ctcae5:C146751 A disorder characterized by a sensation of marked discomfort in the eye. A disorder characterized by a sensation of marked discomfort in the eye. Eye Pain, CTCAE 5.0 Eye pain 10015958 C146751 Eye pain Eye pain A disorder characterized by a sensation of marked discomfort in the eye. NCI A disorder characterized by a sensation of marked discomfort in the eye. CTCAE_v5 Eye Pain, CTCAE 5.0 PT NCI Eye pain PT CTCAE_v5 ctcae5:C146752 A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. Fallopian Tube Obstruction, CTCAE 5.0 Fallopian tube obstruction 10065789 C146752 Fallopian tube obstruction Fallopian tube obstruction A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. NCI A disorder characterized by blockage of the normal flow of the contents in the fallopian tube. CTCAE_v5 Fallopian Tube Obstruction, CTCAE 5.0 PT NCI Fallopian tube obstruction PT CTCAE_v5 ctcae5:C146753 A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. Fatigue Fatigue, CTCAE 5.0 10016256 C146753 Fatigue Fatigue A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. NCI A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. CTCAE_v5 Fatigue PT CTCAE_v5 Fatigue, CTCAE 5.0 PT NCI ctcae5:C146754 A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. Brachial Plexopathy, CTCAE 5.0 Brachial plexopathy 10065417 C146754 Brachial plexopathy Brachial plexopathy A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. NCI A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand. CTCAE_v5 Brachial Plexopathy, CTCAE 5.0 PT NCI Brachial plexopathy PT CTCAE_v5 ctcae5:C146755 A disorder characterized by a sensation of marked discomfort in the gallbladder region. A disorder characterized by a sensation of marked discomfort in the gallbladder region. Gallbladder Pain, CTCAE 5.0 Gallbladder pain 10017638 C146755 Gallbladder pain Gallbladder pain A disorder characterized by a sensation of marked discomfort in the gallbladder region. NCI A disorder characterized by a sensation of marked discomfort in the gallbladder region. CTCAE_v5 Gallbladder Pain, CTCAE 5.0 PT NCI Gallbladder pain PT CTCAE_v5 ctcae5:C146757 A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. Spermatic Cord Obstruction, CTCAE 5.0 Spermatic cord obstruction 10065805 C146757 Spermatic cord obstruction Spermatic cord obstruction A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. NCI A disorder characterized by blockage of the normal flow of the contents of the spermatic cord. CTCAE_v5 Spermatic Cord Obstruction, CTCAE 5.0 PT NCI Spermatic cord obstruction PT CTCAE_v5 ctcae5:C146758 A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. Proteinuria Proteinuria, CTCAE 5.0 10037032 C146758 Proteinuria Proteinuria A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. NCI A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin. CTCAE_v5 Proteinuria PT CTCAE_v5 Proteinuria, CTCAE 5.0 PT NCI ctcae5:C146759 A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. Sinus Tachycardia, CTCAE 5.0 Sinus tachycardia 10040752 C146759 Sinus tachycardia Sinus tachycardia A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. NCI A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates in the sinus node. CTCAE_v5 Sinus Tachycardia, CTCAE 5.0 PT NCI Sinus tachycardia PT CTCAE_v5 ctcae5:C146760 A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. Joint Effusion, CTCAE 5.0 Joint effusion 10023215 C146760 Joint effusion Joint effusion A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. NCI A disorder characterized by excessive fluid in a joint, usually as a result of joint inflammation. CTCAE_v5 Joint Effusion, CTCAE 5.0 PT NCI Joint effusion PT CTCAE_v5 ctcae5:C146761 A disorder characterized by a sensation of marked discomfort of the lip. A disorder characterized by a sensation of marked discomfort of the lip. Lip Pain, CTCAE 5.0 Lip pain 10024561 C146761 Lip pain Lip pain A disorder characterized by a sensation of marked discomfort of the lip. NCI A disorder characterized by a sensation of marked discomfort of the lip. CTCAE_v5 Lip Pain, CTCAE 5.0 PT NCI Lip pain PT CTCAE_v5 ctcae5:C146763 A disorder characterized by a deterioration in memory function. A disorder characterized by a deterioration in memory function. Memory Impairment, CTCAE 5.0 Memory impairment 10027175 C146763 Memory impairment Memory impairment A disorder characterized by a deterioration in memory function. NCI A disorder characterized by a deterioration in memory function. CTCAE_v5 Memory Impairment, CTCAE 5.0 PT NCI Memory impairment PT CTCAE_v5 ctcae5:C146764 A disorder characterized by a queasy sensation and/or the urge to vomit. A disorder characterized by a queasy sensation and/or the urge to vomit. Nausea Nausea, CTCAE 5.0 10028813 C146764 Nausea Nausea A disorder characterized by a queasy sensation and/or the urge to vomit. NCI A disorder characterized by a queasy sensation and/or the urge to vomit. CTCAE_v5 Nausea PT CTCAE_v5 Nausea, CTCAE 5.0 PT NCI ctcae5:C146766 A disorder characterized by a sensation of marked discomfort in the neck area. A disorder characterized by a sensation of marked discomfort in the neck area. Neck Pain, CTCAE 5.0 Neck pain 10028836 C146766 Neck pain Neck pain A disorder characterized by a sensation of marked discomfort in the neck area. NCI A disorder characterized by a sensation of marked discomfort in the neck area. CTCAE_v5 Neck Pain, CTCAE 5.0 PT NCI Neck pain PT CTCAE_v5 ctcae5:C146767 A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis Osteoporosis, CTCAE 5.0 10031282 C146767 Osteoporosis Osteoporosis A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. NCI A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. CTCAE_v5 Osteoporosis PT CTCAE_v5 Osteoporosis, CTCAE 5.0 PT NCI ctcae5:C146768 A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. Hemoglobinuria Hemoglobinuria, CTCAE 5.0 10019489 C146768 Hemoglobinuria Hemoglobinuria A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. NCI A disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine. CTCAE_v5 Hemoglobinuria PT CTCAE_v5 Hemoglobinuria, CTCAE 5.0 PT NCI ctcae5:C146769 A disorder characterized by a sensation of marked discomfort in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. A disorder characterized by a sensation of marked discomfort in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. Ovulation Pain, CTCAE 5.0 Ovulation pain 10033314 C146769 Ovulation pain Ovulation pain A disorder characterized by a sensation of marked discomfort in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. NCI A disorder characterized by a sensation of marked discomfort in one side of the abdomen between menstrual cycles, around the time of the discharge of the ovum from the ovarian follicle. CTCAE_v5 Ovulation Pain, CTCAE 5.0 PT NCI Ovulation pain PT CTCAE_v5 ctcae5:C146770 A disorder characterized by fear and avoidance of light. A disorder characterized by fear and avoidance of light. Photophobia Photophobia, CTCAE 5.0 10034960 C146770 Photophobia Photophobia A disorder characterized by fear and avoidance of light. NCI A disorder characterized by fear and avoidance of light. CTCAE_v5 Photophobia PT CTCAE_v5 Photophobia, CTCAE 5.0 PT NCI ctcae5:C146771 A disorder characterized by difficulty in falling asleep and/or remaining asleep. A disorder characterized by difficulty in falling asleep and/or remaining asleep. Insomnia Insomnia, CTCAE 5.0 10022437 C146771 Insomnia Insomnia A disorder characterized by difficulty in falling asleep and/or remaining asleep. NCI A disorder characterized by difficulty in falling asleep and/or remaining asleep. CTCAE_v5 Insomnia PT CTCAE_v5 Insomnia, CTCAE 5.0 PT NCI ctcae5:C146772 A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head. A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head. Scalp Pain, CTCAE 5.0 Scalp pain 10049120 C146772 Scalp pain Scalp pain A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head. NCI A disorder characterized by a sensation of marked discomfort in the skin covering the top and the back of the head. CTCAE_v5 Scalp Pain, CTCAE 5.0 PT NCI Scalp pain PT CTCAE_v5 ctcae5:C146773 A disorder characterized by a sensation of marked discomfort in a lymph node. A disorder characterized by a sensation of marked discomfort in a lymph node. Lymph Node Pain, CTCAE 5.0 Lymph node pain 10025182 C146773 Lymph node pain Lymph node pain A disorder characterized by a sensation of marked discomfort in a lymph node. NCI A disorder characterized by a sensation of marked discomfort in a lymph node. CTCAE_v5 Lymph Node Pain, CTCAE 5.0 PT NCI Lymph node pain PT CTCAE_v5 ctcae5:C146774 A disorder characterized by a sensation of marked discomfort in the stomach. A disorder characterized by a sensation of marked discomfort in the stomach. Stomach Pain, CTCAE 5.0 Stomach pain 10042112 C146774 Stomach pain Stomach pain A disorder characterized by a sensation of marked discomfort in the stomach. NCI A disorder characterized by a sensation of marked discomfort in the stomach. CTCAE_v5 Stomach Pain, CTCAE 5.0 PT NCI Stomach pain PT CTCAE_v5 ctcae5:C146775 A disorder characterized by involuntary movements of the eyeballs. A disorder characterized by involuntary movements of the eyeballs. Nystagmus Nystagmus, CTCAE 5.0 10029864 C146775 Nystagmus Nystagmus A disorder characterized by involuntary movements of the eyeballs. NCI A disorder characterized by involuntary movements of the eyeballs. CTCAE_v5 Nystagmus PT CTCAE_v5 Nystagmus, CTCAE 5.0 PT NCI ctcae5:C146777 A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. Agitation Agitation, CTCAE 5.0 10001497 C146777 Agitation Agitation A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. NCI A disorder characterized by a state of restlessness associated with unpleasant feelings of irritability and tension. CTCAE_v5 Agitation PT CTCAE_v5 Agitation, CTCAE 5.0 PT NCI ctcae5:C146778 A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. Anxiety Anxiety, CTCAE 5.0 10002855 C146778 Anxiety Anxiety A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. NCI A disorder characterized by apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus. CTCAE_v5 Anxiety PT CTCAE_v5 Anxiety, CTCAE 5.0 PT NCI ctcae5:C146780 A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. Tremor Tremor, CTCAE 5.0 10044565 C146780 Tremor Tremor A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. NCI A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts. CTCAE_v5 Tremor PT CTCAE_v5 Tremor, CTCAE 5.0 PT NCI ctcae5:C146782 A disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. A disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. Tumor Pain, CTCAE 5.0 Tumor pain 10045158 C146782 Tumor pain Tumor pain A disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. NCI A disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis. CTCAE_v5 Tumor Pain, CTCAE 5.0 PT NCI Tumor pain PT CTCAE_v5 ctcae5:C146783 A disorder characterized by a sensation of marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. A disorder characterized by a sensation of marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. Sinus Pain, CTCAE 5.0 Sinus pain 10040747 C146783 Sinus pain Sinus pain A disorder characterized by a sensation of marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. NCI A disorder characterized by a sensation of marked discomfort in the face, between the eyes, or upper teeth originating from the sinuses. CTCAE_v5 Sinus Pain, CTCAE 5.0 PT NCI Sinus pain PT CTCAE_v5 ctcae5:C146785 A disorder characterized by a lack of clear and orderly thought and behavior. A disorder characterized by a lack of clear and orderly thought and behavior. Confusion Confusion, CTCAE 5.0 10010300 C146785 Confusion Confusion A disorder characterized by a lack of clear and orderly thought and behavior. NCI A disorder characterized by a lack of clear and orderly thought and behavior. CTCAE_v5 Confusion PT CTCAE_v5 Confusion, CTCAE 5.0 PT NCI ctcae5:C146786 A disorder characterized by inability to control the flow of urine from the bladder. A disorder characterized by inability to control the flow of urine from the bladder. Urinary Incontinence, CTCAE 5.0 Urinary incontinence 10046543 C146786 Urinary incontinence Urinary incontinence A disorder characterized by inability to control the flow of urine from the bladder. NCI A disorder characterized by inability to control the flow of urine from the bladder. CTCAE_v5 Urinary Incontinence, CTCAE 5.0 PT NCI Urinary incontinence PT CTCAE_v5 ctcae5:C146787 A disorder characterized by inflammation involving the skeletal muscles. A disorder characterized by inflammation involving the skeletal muscles. Myositis Myositis, CTCAE 5.0 10028653 C146787 Myositis Myositis A disorder characterized by inflammation involving the skeletal muscles. NCI A disorder characterized by inflammation involving the skeletal muscles. CTCAE_v5 Myositis PT CTCAE_v5 Myositis, CTCAE 5.0 PT NCI ctcae5:C146788 A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. Cholecystitis Cholecystitis, CTCAE 5.0 10008612 C146788 Cholecystitis Cholecystitis A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. NCI A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones. CTCAE_v5 Cholecystitis PT CTCAE_v5 Cholecystitis, CTCAE 5.0 PT NCI ctcae5:C146789 A disorder characterized by inflammation of the pancreas with no documented pancreas infection. A disorder characterized by inflammation of the pancreas with no documented pancreas infection. Pancreatitis Pancreatitis, CTCAE 5.0 10033645 C146789 Pancreatitis Pancreatitis A disorder characterized by inflammation of the pancreas with no documented pancreas infection. NCI A disorder characterized by inflammation of the pancreas with no documented pancreas infection. CTCAE_v5 Pancreatitis PT CTCAE_v5 Pancreatitis, CTCAE 5.0 PT NCI ctcae5:C28245 A disorder characterized by inhalation of solids or liquids into the lungs. A disorder characterized by inhalation of solids or liquids into the lungs. Aspiration Aspiration, CTCAE 10003504 C28245 Aspiration Aspiration A disorder characterized by inhalation of solids or liquids into the lungs. NCI A disorder characterized by inhalation of solids or liquids into the lungs. CTCAE_v5 Aspiration PT CTCAE_v5 Aspiration, CTCAE PT NCI ctcae5:C54741 A disorder characterized by inflammation involving the wall of a vessel. A disorder characterized by inflammation involving the wall of a vessel. Vasculitis Vasculitis, CTCAE 10047115 C54741 Vasculitis Vasculitis A disorder characterized by inflammation involving the wall of a vessel. NCI A disorder characterized by inflammation involving the wall of a vessel. CTCAE_v5 Vasculitis PT CTCAE_v5 Vasculitis, CTCAE PT NCI ctcae5:C54746 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Vasculitis Grade 1 Vasculitis, CTCAE 10047115 C54746 Grade 1 Vasculitis Grade 1 Vasculitis Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Vasculitis PT CTCAE_v5 Grade 1 Vasculitis, CTCAE PT NCI ctcae5:C54751 Moderate symptoms, medical intervention indicated Moderate symptoms, medical intervention indicated Grade 2 Vasculitis Grade 2 Vasculitis, CTCAE 10047115 C54751 Grade 2 Vasculitis Grade 2 Vasculitis Moderate symptoms, medical intervention indicated NCI Moderate symptoms, medical intervention indicated CTCAE_v5 Grade 2 Vasculitis PT CTCAE_v5 Grade 2 Vasculitis, CTCAE PT NCI ctcae5:C54755 Severe arthralgia or arthritis; extensive rash; steroids or IV fluids indicated Severe arthralgia or arthritis; extensive rash; steroids or IV fluids indicated Grade 3 Serum Sickness, CTCAE Grade 3 Serum sickness 10040400 C54755 Grade 3 Serum sickness Grade 3 Serum sickness Severe arthralgia or arthritis; extensive rash; steroids or IV fluids indicated NCI Severe arthralgia or arthritis; extensive rash; steroids or IV fluids indicated CTCAE_v5 Grade 3 Serum Sickness, CTCAE PT NCI Grade 3 Serum sickness PT CTCAE_v5 ctcae5:C54756 Severe symptoms, medical intervention indicated (e.g., steroids) Severe symptoms, medical intervention indicated (e.g., steroids) Grade 3 Vasculitis Grade 3 Vasculitis, CTCAE 10047115 C54756 Grade 3 Vasculitis Grade 3 Vasculitis Severe symptoms, medical intervention indicated (e.g., steroids) NCI Severe symptoms, medical intervention indicated (e.g., steroids) CTCAE_v5 Grade 3 Vasculitis PT CTCAE_v5 Grade 3 Vasculitis, CTCAE PT NCI ctcae5:C54760 Life-threatening consequences; evidence of peripheral or visceral ischemia; urgent intervention indicated Life-threatening consequences; evidence of peripheral or visceral ischemia; urgent intervention indicated Grade 4 Vasculitis Grade 4 Vasculitis, CTCAE 10047115 C54760 Grade 4 Vasculitis Grade 4 Vasculitis Life-threatening consequences; evidence of peripheral or visceral ischemia; urgent intervention indicated NCI Life-threatening consequences; evidence of peripheral or visceral ischemia; urgent intervention indicated CTCAE_v5 Grade 4 Vasculitis PT CTCAE_v5 Grade 4 Vasculitis, CTCAE PT NCI ctcae5:C54764 Death Death Grade 5 Serum Sickness, CTCAE Grade 5 Serum sickness 10040400 C54764 Grade 5 Serum sickness Grade 5 Serum sickness Death NCI Death CTCAE_v5 Grade 5 Serum Sickness, CTCAE PT NCI Grade 5 Serum sickness PT CTCAE_v5 ctcae5:C54765 Death Death Grade 5 Vasculitis Grade 5 Vasculitis, CTCAE 10047115 C54765 Grade 5 Vasculitis Grade 5 Vasculitis Death NCI Death CTCAE_v5 Grade 5 Vasculitis PT CTCAE_v5 Grade 5 Vasculitis, CTCAE PT NCI ctcae5:C54767 A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. Atrial Fibrillation, CTCAE Atrial fibrillation 10003658 C54767 Atrial fibrillation Atrial fibrillation A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. NCI A disorder characterized by a dysrhythmia without discernible P waves and an irregular ventricular response due to multiple reentry circuits. The rhythm disturbance originates above the ventricles. CTCAE_v5 Atrial Fibrillation, CTCAE PT NCI Atrial fibrillation PT CTCAE_v5 ctcae5:C54768 A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. Atrial Flutter, CTCAE Atrial flutter 10003662 C54768 Atrial flutter Atrial flutter A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. NCI A disorder characterized by a dysrhythmia with organized rhythmic atrial contractions with a rate of 200-300 beats per minute. The rhythm disturbance originates in the atria. CTCAE_v5 Atrial Flutter, CTCAE PT NCI Atrial flutter PT CTCAE_v5 ctcae5:C54771 A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. Mobitz Type I, CTCAE Mobitz type I 10027787 C54771 Mobitz type I Mobitz type I A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. NCI A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. CTCAE_v5 Mobitz Type I, CTCAE PT NCI Mobitz type I PT CTCAE_v5 ctcae5:C54772 A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. Mobitz (Type) II Atrioventricular Block, CTCAE Mobitz (type) II atrioventricular block 10027786 C54772 Mobitz (type) II atrioventricular block Mobitz (type) II atrioventricular block A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. NCI A disorder characterized by a dysrhythmia with relatively constant PR interval prior to the block of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles. CTCAE_v5 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54777 Periods of asystole; non-urgent medical management indicated Periods of asystole; non-urgent medical management indicated Grade 1 Asystole Grade 1 Asystole, CTCAE 10003586 C54777 Grade 1 Asystole Grade 1 Asystole Periods of asystole; non-urgent medical management indicated NCI Periods of asystole; non-urgent medical management indicated CTCAE_v5 Grade 1 Asystole PT CTCAE_v5 Grade 1 Asystole, CTCAE PT NCI ctcae5:C54778 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Atrial Fibrillation, CTCAE Grade 1 Atrial fibrillation 10003658 C54778 Grade 1 Atrial fibrillation Grade 1 Atrial fibrillation Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Atrial Fibrillation, CTCAE PT NCI Grade 1 Atrial fibrillation PT CTCAE_v5 ctcae5:C54779 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Atrial Flutter, CTCAE Grade 1 Atrial flutter 10003662 C54779 Grade 1 Atrial flutter Grade 1 Atrial flutter Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Atrial Flutter, CTCAE PT NCI Grade 1 Atrial flutter PT CTCAE_v5 ctcae5:C54782 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Mobitz Type I, CTCAE Grade 1 Mobitz type I 10027787 C54782 Grade 1 Mobitz type I Grade 1 Mobitz type I Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Mobitz Type I, CTCAE PT NCI Grade 1 Mobitz type I PT CTCAE_v5 ctcae5:C54783 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Mobitz (Type) II Atrioventricular Block, CTCAE Grade 1 Mobitz (type) II atrioventricular block 10027786 C54783 Grade 1 Mobitz (type) II atrioventricular block Grade 1 Mobitz (type) II atrioventricular block Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Grade 1 Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54790 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Palpitations Grade 1 Palpitations, CTCAE 10033557 C54790 Grade 1 Palpitations Grade 1 Palpitations Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Palpitations PT CTCAE_v5 Grade 1 Palpitations, CTCAE PT NCI ctcae5:C54793 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Sick Sinus Syndrome, CTCAE Grade 1 Sick sinus syndrome 10040639 C54793 Grade 1 Sick sinus syndrome Grade 1 Sick sinus syndrome Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Sick Sinus Syndrome, CTCAE PT NCI Grade 1 Sick sinus syndrome PT CTCAE_v5 ctcae5:C54795 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Sinus Bradycardia, CTCAE Grade 1 Sinus bradycardia 10040741 C54795 Grade 1 Sinus bradycardia Grade 1 Sinus bradycardia Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Sinus Bradycardia, CTCAE PT NCI Grade 1 Sinus bradycardia PT CTCAE_v5 ctcae5:C54796 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Sinus Tachycardia, CTCAE Grade 1 Sinus tachycardia 10040752 C54796 Grade 1 Sinus tachycardia Grade 1 Sinus tachycardia Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Sinus Tachycardia, CTCAE PT NCI Grade 1 Sinus tachycardia PT CTCAE_v5 ctcae5:C54800 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Supraventricular Tachycardia, CTCAE Grade 1 Supraventricular tachycardia 10042604 C54800 Grade 1 Supraventricular tachycardia Grade 1 Supraventricular tachycardia Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Supraventricular Tachycardia, CTCAE PT NCI Grade 1 Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54809 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Atrial Fibrillation, CTCAE Grade 2 Atrial fibrillation 10003658 C54809 Grade 2 Atrial fibrillation Grade 2 Atrial fibrillation Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Atrial Fibrillation, CTCAE PT NCI Grade 2 Atrial fibrillation PT CTCAE_v5 ctcae5:C54810 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Atrial Flutter, CTCAE Grade 2 Atrial flutter 10003662 C54810 Grade 2 Atrial flutter Grade 2 Atrial flutter Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Atrial Flutter, CTCAE PT NCI Grade 2 Atrial flutter PT CTCAE_v5 ctcae5:C54813 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Mobitz Type I, CTCAE Grade 2 Mobitz type I 10027787 C54813 Grade 2 Mobitz type I Grade 2 Mobitz type I Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Mobitz Type I, CTCAE PT NCI Grade 2 Mobitz type I PT CTCAE_v5 ctcae5:C54814 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Mobitz (Type) II Atrioventricular Block, CTCAE Grade 2 Mobitz (type) II atrioventricular block 10027786 C54814 Grade 2 Mobitz (type) II atrioventricular block Grade 2 Mobitz (type) II atrioventricular block Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Grade 2 Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54821 Intervention indicated Intervention indicated Grade 2 Palpitations Grade 2 Palpitations, CTCAE 10033557 C54821 Grade 2 Palpitations Grade 2 Palpitations Intervention indicated NCI Intervention indicated CTCAE_v5 Grade 2 Palpitations PT CTCAE_v5 Grade 2 Palpitations, CTCAE PT NCI ctcae5:C54824 Symptomatic, intervention not indicated; change in medication initiated Symptomatic, intervention not indicated; change in medication initiated Grade 2 Sick Sinus Syndrome, CTCAE Grade 2 Sick sinus syndrome 10040639 C54824 Grade 2 Sick sinus syndrome Grade 2 Sick sinus syndrome Symptomatic, intervention not indicated; change in medication initiated NCI Symptomatic, intervention not indicated; change in medication initiated CTCAE_v5 Grade 2 Sick Sinus Syndrome, CTCAE PT NCI Grade 2 Sick sinus syndrome PT CTCAE_v5 ctcae5:C54826 Symptomatic, intervention not indicated; change in medication initiated Symptomatic, intervention not indicated; change in medication initiated Grade 2 Sinus Bradycardia, CTCAE Grade 2 Sinus bradycardia 10040741 C54826 Grade 2 Sinus bradycardia Grade 2 Sinus bradycardia Symptomatic, intervention not indicated; change in medication initiated NCI Symptomatic, intervention not indicated; change in medication initiated CTCAE_v5 Grade 2 Sinus Bradycardia, CTCAE PT NCI Grade 2 Sinus bradycardia PT CTCAE_v5 ctcae5:C54827 Symptomatic; non-urgent medical intervention indicated Symptomatic; non-urgent medical intervention indicated Grade 2 Sinus Tachycardia, CTCAE Grade 2 Sinus tachycardia 10040752 C54827 Grade 2 Sinus tachycardia Grade 2 Sinus tachycardia Symptomatic; non-urgent medical intervention indicated NCI Symptomatic; non-urgent medical intervention indicated CTCAE_v5 Grade 2 Sinus Tachycardia, CTCAE PT NCI Grade 2 Sinus tachycardia PT CTCAE_v5 ctcae5:C54831 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Supraventricular Tachycardia, CTCAE Grade 2 Supraventricular tachycardia 10042604 C54831 Grade 2 Supraventricular tachycardia Grade 2 Supraventricular tachycardia Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Supraventricular Tachycardia, CTCAE PT NCI Grade 2 Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54838 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Ventricular Tachycardia, CTCAE Grade 2 Ventricular tachycardia 10047302 C54838 Grade 2 Ventricular tachycardia Grade 2 Ventricular tachycardia Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Ventricular Tachycardia, CTCAE PT NCI Grade 2 Ventricular tachycardia PT CTCAE_v5 ctcae5:C54841 Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation; new onset Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation; new onset Grade 3 Atrial Fibrillation, CTCAE Grade 3 Atrial fibrillation 10003658 C54841 Grade 3 Atrial fibrillation Grade 3 Atrial fibrillation Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation; new onset NCI Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation; new onset CTCAE_v5 Grade 3 Atrial Fibrillation, CTCAE PT NCI Grade 3 Atrial fibrillation PT CTCAE_v5 ctcae5:C54842 Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation Grade 3 Atrial Flutter, CTCAE Grade 3 Atrial flutter 10003662 C54842 Grade 3 Atrial flutter Grade 3 Atrial flutter Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation NCI Symptomatic, urgent intervention indicated; device (e.g., pacemaker); ablation CTCAE_v5 Grade 3 Atrial Flutter, CTCAE PT NCI Grade 3 Atrial flutter PT CTCAE_v5 ctcae5:C54845 Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker) Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker) Grade 3 Mobitz Type I, CTCAE Grade 3 Mobitz type I 10027787 C54845 Grade 3 Mobitz type I Grade 3 Mobitz type I Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker) NCI Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker) CTCAE_v5 Grade 3 Mobitz Type I, CTCAE PT NCI Grade 3 Mobitz type I PT CTCAE_v5 ctcae5:C54846 Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset Grade 3 Mobitz (Type) II Atrioventricular Block, CTCAE Grade 3 Mobitz (type) II atrioventricular block 10027786 C54846 Grade 3 Mobitz (type) II atrioventricular block Grade 3 Mobitz (type) II atrioventricular block Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset NCI Symptomatic and incompletely controlled medically, or controlled with device (e.g., pacemaker); new onset CTCAE_v5 Grade 3 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Grade 3 Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54855 Symptomatic, intervention indicated Symptomatic, intervention indicated Grade 3 Sick Sinus Syndrome, CTCAE Grade 3 Sick sinus syndrome 10040639 C54855 Grade 3 Sick sinus syndrome Grade 3 Sick sinus syndrome Symptomatic, intervention indicated NCI Symptomatic, intervention indicated CTCAE_v5 Grade 3 Sick Sinus Syndrome, CTCAE PT NCI Grade 3 Sick sinus syndrome PT CTCAE_v5 ctcae5:C54857 Symptomatic, intervention indicated Symptomatic, intervention indicated Grade 3 Sinus Bradycardia, CTCAE Grade 3 Sinus bradycardia 10040741 C54857 Grade 3 Sinus bradycardia Grade 3 Sinus bradycardia Symptomatic, intervention indicated NCI Symptomatic, intervention indicated CTCAE_v5 Grade 3 Sinus Bradycardia, CTCAE PT NCI Grade 3 Sinus bradycardia PT CTCAE_v5 ctcae5:C54858 Urgent medical intervention indicated Urgent medical intervention indicated Grade 3 Sinus Tachycardia, CTCAE Grade 3 Sinus tachycardia 10040752 C54858 Grade 3 Sinus tachycardia Grade 3 Sinus tachycardia Urgent medical intervention indicated NCI Urgent medical intervention indicated CTCAE_v5 Grade 3 Sinus Tachycardia, CTCAE PT NCI Grade 3 Sinus tachycardia PT CTCAE_v5 ctcae5:C54862 Symptomatic, urgent intervention indicated Symptomatic, urgent intervention indicated Grade 3 Supraventricular Tachycardia, CTCAE Grade 3 Supraventricular tachycardia 10042604 C54862 Grade 3 Supraventricular tachycardia Grade 3 Supraventricular tachycardia Symptomatic, urgent intervention indicated NCI Symptomatic, urgent intervention indicated CTCAE_v5 Grade 3 Supraventricular Tachycardia, CTCAE PT NCI Grade 3 Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54869 Symptomatic, urgent intervention indicated Symptomatic, urgent intervention indicated Grade 3 Ventricular Tachycardia, CTCAE Grade 3 Ventricular tachycardia 10047302 C54869 Grade 3 Ventricular tachycardia Grade 3 Ventricular tachycardia Symptomatic, urgent intervention indicated NCI Symptomatic, urgent intervention indicated CTCAE_v5 Grade 3 Ventricular Tachycardia, CTCAE PT NCI Grade 3 Ventricular tachycardia PT CTCAE_v5 ctcae5:C54871 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Asystole Grade 4 Asystole, CTCAE 10003586 C54871 Grade 4 Asystole Grade 4 Asystole Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Asystole PT CTCAE_v5 Grade 4 Asystole, CTCAE PT NCI ctcae5:C54872 Life-threatening consequences; embolus requiring urgent intervention Life-threatening consequences; embolus requiring urgent intervention Grade 4 Atrial Fibrillation, CTCAE Grade 4 Atrial fibrillation 10003658 C54872 Grade 4 Atrial fibrillation Grade 4 Atrial fibrillation Life-threatening consequences; embolus requiring urgent intervention NCI Life-threatening consequences; embolus requiring urgent intervention CTCAE_v5 Grade 4 Atrial Fibrillation, CTCAE PT NCI Grade 4 Atrial fibrillation PT CTCAE_v5 ctcae5:C54873 Life-threatening consequences; embolus requiring urgent intervention Life-threatening consequences; embolus requiring urgent intervention Grade 4 Atrial Flutter, CTCAE Grade 4 Atrial flutter 10003662 C54873 Grade 4 Atrial flutter Grade 4 Atrial flutter Life-threatening consequences; embolus requiring urgent intervention NCI Life-threatening consequences; embolus requiring urgent intervention CTCAE_v5 Grade 4 Atrial Flutter, CTCAE PT NCI Grade 4 Atrial flutter PT CTCAE_v5 ctcae5:C54876 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mobitz Type I, CTCAE Grade 4 Mobitz type I 10027787 C54876 Grade 4 Mobitz type I Grade 4 Mobitz type I Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mobitz Type I, CTCAE PT NCI Grade 4 Mobitz type I PT CTCAE_v5 ctcae5:C54877 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mobitz (Type) II Atrioventricular Block, CTCAE Grade 4 Mobitz (type) II atrioventricular block 10027786 C54877 Grade 4 Mobitz (type) II atrioventricular block Grade 4 Mobitz (type) II atrioventricular block Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Grade 4 Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54886 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Sick Sinus Syndrome, CTCAE Grade 4 Sick sinus syndrome 10040639 C54886 Grade 4 Sick sinus syndrome Grade 4 Sick sinus syndrome Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Sick Sinus Syndrome, CTCAE PT NCI Grade 4 Sick sinus syndrome PT CTCAE_v5 ctcae5:C54888 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Sinus Bradycardia, CTCAE Grade 4 Sinus bradycardia 10040741 C54888 Grade 4 Sinus bradycardia Grade 4 Sinus bradycardia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Sinus Bradycardia, CTCAE PT NCI Grade 4 Sinus bradycardia PT CTCAE_v5 ctcae5:C54893 Life-threatening consequences Life-threatening consequences Grade 4 Supraventricular Tachycardia, CTCAE Grade 4 Supraventricular tachycardia 10042604 C54893 Grade 4 Supraventricular tachycardia Grade 4 Supraventricular tachycardia Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Supraventricular Tachycardia, CTCAE PT NCI Grade 4 Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54898 Life-threatening consequences; hemodynamic compromise Life-threatening consequences; hemodynamic compromise Grade 4 Ventricular Fibrillation, CTCAE Grade 4 Ventricular fibrillation 10047290 C54898 Grade 4 Ventricular fibrillation Grade 4 Ventricular fibrillation Life-threatening consequences; hemodynamic compromise NCI Life-threatening consequences; hemodynamic compromise CTCAE_v5 Grade 4 Ventricular Fibrillation, CTCAE PT NCI Grade 4 Ventricular fibrillation PT CTCAE_v5 ctcae5:C54900 Life-threatening consequences; hemodynamic compromise Life-threatening consequences; hemodynamic compromise Grade 4 Ventricular Tachycardia, CTCAE Grade 4 Ventricular tachycardia 10047302 C54900 Grade 4 Ventricular tachycardia Grade 4 Ventricular tachycardia Life-threatening consequences; hemodynamic compromise NCI Life-threatening consequences; hemodynamic compromise CTCAE_v5 Grade 4 Ventricular Tachycardia, CTCAE PT NCI Grade 4 Ventricular tachycardia PT CTCAE_v5 ctcae5:C54902 Death Death Grade 5 Asystole Grade 5 Asystole, CTCAE 10003586 C54902 Grade 5 Asystole Grade 5 Asystole Death NCI Death CTCAE_v5 Grade 5 Asystole PT CTCAE_v5 Grade 5 Asystole, CTCAE PT NCI ctcae5:C54903 Death Death Grade 5 Atrial Fibrillation, CTCAE Grade 5 Atrial fibrillation 10003658 C54903 Grade 5 Atrial fibrillation Grade 5 Atrial fibrillation Death NCI Death CTCAE_v5 Grade 5 Atrial Fibrillation, CTCAE PT NCI Grade 5 Atrial fibrillation PT CTCAE_v5 ctcae5:C54904 Death Death Grade 5 Atrial Flutter, CTCAE Grade 5 Atrial flutter 10003662 C54904 Grade 5 Atrial flutter Grade 5 Atrial flutter Death NCI Death CTCAE_v5 Grade 5 Atrial Flutter, CTCAE PT NCI Grade 5 Atrial flutter PT CTCAE_v5 ctcae5:C54907 Death Death Grade 5 Mobitz Type I, CTCAE Grade 5 Mobitz type I 10027787 C54907 Grade 5 Mobitz type I Grade 5 Mobitz type I Death NCI Death CTCAE_v5 Grade 5 Mobitz Type I, CTCAE PT NCI Grade 5 Mobitz type I PT CTCAE_v5 ctcae5:C54908 Death Death Grade 5 Mobitz (Type) II Atrioventricular Block, CTCAE Grade 5 Mobitz (type) II atrioventricular block 10027786 C54908 Grade 5 Mobitz (type) II atrioventricular block Grade 5 Mobitz (type) II atrioventricular block Death NCI Death CTCAE_v5 Grade 5 Mobitz (Type) II Atrioventricular Block, CTCAE PT NCI Grade 5 Mobitz (type) II atrioventricular block PT CTCAE_v5 ctcae5:C54917 Death Death Grade 5 Sick Sinus Syndrome, CTCAE Grade 5 Sick sinus syndrome 10040639 C54917 Grade 5 Sick sinus syndrome Grade 5 Sick sinus syndrome Death NCI Death CTCAE_v5 Grade 5 Sick Sinus Syndrome, CTCAE PT NCI Grade 5 Sick sinus syndrome PT CTCAE_v5 ctcae5:C54919 Death Death Grade 5 Sinus Bradycardia, CTCAE Grade 5 Sinus bradycardia 10040741 C54919 Grade 5 Sinus bradycardia Grade 5 Sinus bradycardia Death NCI Death CTCAE_v5 Grade 5 Sinus Bradycardia, CTCAE PT NCI Grade 5 Sinus bradycardia PT CTCAE_v5 ctcae5:C54924 Death Death Grade 5 Supraventricular Tachycardia, CTCAE Grade 5 Supraventricular tachycardia 10042604 C54924 Grade 5 Supraventricular tachycardia Grade 5 Supraventricular tachycardia Death NCI Death CTCAE_v5 Grade 5 Supraventricular Tachycardia, CTCAE PT NCI Grade 5 Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54929 Death Death Grade 5 Ventricular Fibrillation, CTCAE Grade 5 Ventricular fibrillation 10047290 C54929 Grade 5 Ventricular fibrillation Grade 5 Ventricular fibrillation Death NCI Death CTCAE_v5 Grade 5 Ventricular Fibrillation, CTCAE PT NCI Grade 5 Ventricular fibrillation PT CTCAE_v5 ctcae5:C54931 Death Death Grade 5 Ventricular Tachycardia, CTCAE Grade 5 Ventricular tachycardia 10047302 C54931 Grade 5 Ventricular tachycardia Grade 5 Ventricular tachycardia Death NCI Death CTCAE_v5 Grade 5 Ventricular Tachycardia, CTCAE PT NCI Grade 5 Ventricular tachycardia PT CTCAE_v5 ctcae5:C54935 A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. Palpitations Palpitations, CTCAE 10033557 C54935 Palpitations Palpitations A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. NCI A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart. CTCAE_v5 Palpitations PT CTCAE_v5 Palpitations, CTCAE PT NCI ctcae5:C54938 A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. Sick Sinus Syndrome, CTCAE Sick sinus syndrome 10040639 C54938 Sick sinus syndrome Sick sinus syndrome A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. NCI A disorder characterized by a dysrhythmia with alternating periods of bradycardia and atrial tachycardia accompanied by syncope, fatigue and dizziness. CTCAE_v5 Sick Sinus Syndrome, CTCAE PT NCI Sick sinus syndrome PT CTCAE_v5 ctcae5:C54940 A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. Sinus Bradycardia, CTCAE Sinus bradycardia 10040741 C54940 Sinus bradycardia Sinus bradycardia A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. NCI A disorder characterized by a dysrhythmia with a heart rate less than 60 beats per minute that originates in the sinus node. CTCAE_v5 Sinus Bradycardia, CTCAE PT NCI Sinus bradycardia PT CTCAE_v5 ctcae5:C54945 A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. Supraventricular Tachycardia, CTCAE Supraventricular tachycardia 10042604 C54945 Supraventricular tachycardia Supraventricular tachycardia A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. NCI A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates above the ventricles. CTCAE_v5 Supraventricular Tachycardia, CTCAE PT NCI Supraventricular tachycardia PT CTCAE_v5 ctcae5:C54969 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Tinnitus Grade 2 Tinnitus, CTCAE 10043882 C54969 Grade 2 Tinnitus Grade 2 Tinnitus Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Tinnitus PT CTCAE_v5 Grade 2 Tinnitus, CTCAE PT NCI ctcae5:C54975 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Tinnitus Grade 3 Tinnitus, CTCAE 10043882 C54975 Grade 3 Tinnitus Grade 3 Tinnitus Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Tinnitus PT CTCAE_v5 Grade 3 Tinnitus, CTCAE PT NCI ctcae5:C54996 Adult: Systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg; Pediatric: Systolic/diastolic BP >90th percentile but< 95th percentile; Adolescent: BP >= 120/80 even if < 95th percentile Adult: Systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg; Pediatric: Systolic/diastolic BP >90th percentile but< 95th percentile; Adolescent: BP >= 120/80 even if < 95th percentile Grade 1 Hypertension Grade 1 Hypertension, CTCAE 10020772 C54996 Grade 1 Hypertension Grade 1 Hypertension Adult: Systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg; Pediatric: Systolic/diastolic BP >90th percentile but< 95th percentile; Adolescent: BP >= 120/80 even if < 95th percentile NCI Adult: Systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg; Pediatric: Systolic/diastolic BP >90th percentile but< 95th percentile; Adolescent: BP >= 120/80 even if < 95th percentile CTCAE_v5 Grade 1 Hypertension PT CTCAE_v5 Grade 1 Hypertension, CTCAE PT NCI ctcae5:C54997 Asymptomatic, intervention not indicated Asymptomatic, intervention not indicated Grade 1 Hypotension Grade 1 Hypotension, CTCAE 10021097 C54997 Grade 1 Hypotension Grade 1 Hypotension Asymptomatic, intervention not indicated NCI Asymptomatic, intervention not indicated CTCAE_v5 Grade 1 Hypotension PT CTCAE_v5 Grade 1 Hypotension, CTCAE PT NCI ctcae5:C55001 Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis Grade 1 Pericarditis Grade 1 Pericarditis, CTCAE 10034484 C55001 Grade 1 Pericarditis Grade 1 Pericarditis Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis NCI Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis CTCAE_v5 Grade 1 Pericarditis PT CTCAE_v5 Grade 1 Pericarditis, CTCAE PT NCI ctcae5:C55002 Minimal dyspnea; findings on physical exam or other evaluation Minimal dyspnea; findings on physical exam or other evaluation Grade 1 Pulmonary Hypertension, CTCAE Grade 1 Pulmonary hypertension 10037400 C55002 Grade 1 Pulmonary hypertension Grade 1 Pulmonary hypertension Minimal dyspnea; findings on physical exam or other evaluation NCI Minimal dyspnea; findings on physical exam or other evaluation CTCAE_v5 Grade 1 Pulmonary Hypertension, CTCAE PT NCI Grade 1 Pulmonary hypertension PT CTCAE_v5 ctcae5:C55003 Imaging findings only Imaging findings only Grade 1 Restrictive Cardiomyopathy, CTCAE Grade 1 Restrictive cardiomyopathy 10038748 C55003 Grade 1 Restrictive cardiomyopathy Grade 1 Restrictive cardiomyopathy Imaging findings only NCI Imaging findings only CTCAE_v5 Grade 1 Restrictive Cardiomyopathy, CTCAE PT NCI Grade 1 Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55004 Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities Grade 1 Right Ventricular Dysfunction, CTCAE Grade 1 Right ventricular dysfunction 10058597 C55004 Grade 1 Right ventricular dysfunction Grade 1 Right ventricular dysfunction Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities NCI Asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities CTCAE_v5 Grade 1 Right Ventricular Dysfunction, CTCAE PT NCI Grade 1 Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55008 Adult: Systolic BP 140-159 mm Hg or diastolic BP 90-99 mm Hg if previously WNL; change in baseline medical intervention indicated; recurrent or persistent (>=24 hrs); symptomatic increase by >20 mm Hg (diastolic) or to >140/90 mm Hg; monotherapy indicated initiated; Pediatric and adolescent: Recurrent or persistent (>=24 hrs) BP >ULN; monotherapy indicated; systolic and /or diastolic BP between the 95th percentile and 5 mmHg above the 99th percentile; Adolescent: Systolic between 130-139 or diastolic between 80-89 even if < 95th percentile Adult: Systolic BP 140-159 mm Hg or diastolic BP 90-99 mm Hg if previously WNL; change in baseline medical intervention indicated; recurrent or persistent (>=24 hrs); symptomatic increase by >20 mm Hg (diastolic) or to >140/90 mm Hg; monotherapy indicated initiated; Pediatric and adolescent: Recurrent or persistent (>=24 hrs) BP >ULN; monotherapy indicated; systolic and /or diastolic BP between the 95th percentile and 5 mmHg above the 99th percentile; Adolescent: Systolic between 130-139 or diastolic between 80-89 even if < 95th percentile Grade 2 Hypertension Grade 2 Hypertension, CTCAE 10020772 C55008 Grade 2 Hypertension Grade 2 Hypertension Adult: Systolic BP 140-159 mm Hg or diastolic BP 90-99 mm Hg if previously WNL; change in baseline medical intervention indicated; recurrent or persistent (>=24 hrs); symptomatic increase by >20 mm Hg (diastolic) or to >140/90 mm Hg; monotherapy indicated initiated; Pediatric and adolescent: Recurrent or persistent (>=24 hrs) BP >ULN; monotherapy indicated; systolic and /or diastolic BP between the 95th percentile and 5 mmHg above the 99th percentile; Adolescent: Systolic between 130-139 or diastolic between 80-89 even if < 95th percentile NCI Adult: Systolic BP 140-159 mm Hg or diastolic BP 90-99 mm Hg if previously WNL; change in baseline medical intervention indicated; recurrent or persistent (>=24 hrs); symptomatic increase by >20 mm Hg (diastolic) or to >140/90 mm Hg; monotherapy indicated initiated; Pediatric and adolescent: Recurrent or persistent (>=24 hrs) BP >ULN; monotherapy indicated; systolic and /or diastolic BP between the 95th percentile and 5 mmHg above the 99th percentile; Adolescent: Systolic between 130-139 or diastolic between 80-89 even if < 95th percentile CTCAE_v5 Grade 2 Hypertension PT CTCAE_v5 Grade 2 Hypertension, CTCAE PT NCI ctcae5:C55009 Non-urgent medical intervention indicated Non-urgent medical intervention indicated Grade 2 Hypotension Grade 2 Hypotension, CTCAE 10021097 C55009 Grade 2 Hypotension Grade 2 Hypotension Non-urgent medical intervention indicated NCI Non-urgent medical intervention indicated CTCAE_v5 Grade 2 Hypotension PT CTCAE_v5 Grade 2 Hypotension, CTCAE PT NCI ctcae5:C55012 Symptomatic pericarditis (e.g., chest pain) Symptomatic pericarditis (e.g., chest pain) Grade 2 Pericarditis Grade 2 Pericarditis, CTCAE 10034484 C55012 Grade 2 Pericarditis Grade 2 Pericarditis Symptomatic pericarditis (e.g., chest pain) NCI Symptomatic pericarditis (e.g., chest pain) CTCAE_v5 Grade 2 Pericarditis PT CTCAE_v5 Grade 2 Pericarditis, CTCAE PT NCI ctcae5:C55013 Moderate dyspnea, cough; requiring evaluation by cardiac catheterization and medical intervention Moderate dyspnea, cough; requiring evaluation by cardiac catheterization and medical intervention Grade 2 Pulmonary Hypertension, CTCAE Grade 2 Pulmonary hypertension 10037400 C55013 Grade 2 Pulmonary hypertension Grade 2 Pulmonary hypertension Moderate dyspnea, cough; requiring evaluation by cardiac catheterization and medical intervention NCI Moderate dyspnea, cough; requiring evaluation by cardiac catheterization and medical intervention CTCAE_v5 Grade 2 Pulmonary Hypertension, CTCAE PT NCI Grade 2 Pulmonary hypertension PT CTCAE_v5 ctcae5:C55014 Symptomatic without signs of heart failure Symptomatic without signs of heart failure Grade 2 Restrictive Cardiomyopathy, CTCAE Grade 2 Restrictive cardiomyopathy 10038748 C55014 Grade 2 Restrictive cardiomyopathy Grade 2 Restrictive cardiomyopathy Symptomatic without signs of heart failure NCI Symptomatic without signs of heart failure CTCAE_v5 Grade 2 Restrictive Cardiomyopathy, CTCAE PT NCI Grade 2 Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55015 Symptoms with moderate activity or exertion Symptoms with moderate activity or exertion Grade 2 Right Ventricular Dysfunction, CTCAE Grade 2 Right ventricular dysfunction 10058597 C55015 Grade 2 Right ventricular dysfunction Grade 2 Right ventricular dysfunction Symptoms with moderate activity or exertion NCI Symptoms with moderate activity or exertion CTCAE_v5 Grade 2 Right Ventricular Dysfunction, CTCAE PT NCI Grade 2 Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55020 Adult: Systolic BP >=160 mm Hg or diastolic BP >=100 mm Hg; medical intervention indicated; more than one drug or more intensive therapy than previously used indicated; Pediatric and adolescent: Systolic and/or diastolic > 5 mmHg above the 99th percentile Adult: Systolic BP >=160 mm Hg or diastolic BP >=100 mm Hg; medical intervention indicated; more than one drug or more intensive therapy than previously used indicated; Pediatric and adolescent: Systolic and/or diastolic > 5 mmHg above the 99th percentile Grade 3 Hypertension Grade 3 Hypertension, CTCAE 10020772 C55020 Grade 3 Hypertension Grade 3 Hypertension Adult: Systolic BP >=160 mm Hg or diastolic BP >=100 mm Hg; medical intervention indicated; more than one drug or more intensive therapy than previously used indicated; Pediatric and adolescent: Systolic and/or diastolic > 5 mmHg above the 99th percentile NCI Adult: Systolic BP >=160 mm Hg or diastolic BP >=100 mm Hg; medical intervention indicated; more than one drug or more intensive therapy than previously used indicated; Pediatric and adolescent: Systolic and/or diastolic > 5 mmHg above the 99th percentile CTCAE_v5 Grade 3 Hypertension PT CTCAE_v5 Grade 3 Hypertension, CTCAE PT NCI ctcae5:C55021 Medical intervention indicated; hospitalization indicated Medical intervention indicated; hospitalization indicated Grade 3 Hypotension Grade 3 Hypotension, CTCAE 10021097 C55021 Grade 3 Hypotension Grade 3 Hypotension Medical intervention indicated; hospitalization indicated NCI Medical intervention indicated; hospitalization indicated CTCAE_v5 Grade 3 Hypotension PT CTCAE_v5 Grade 3 Hypotension, CTCAE PT NCI ctcae5:C55023 Symptomatic due to drop in ejection fraction responsive to intervention Symptomatic due to drop in ejection fraction responsive to intervention Grade 3 Left Ventricular Systolic Dysfunction, CTCAE Grade 3 Left ventricular systolic dysfunction 10069501 C55023 Grade 3 Left ventricular systolic dysfunction Grade 3 Left ventricular systolic dysfunction Symptomatic due to drop in ejection fraction responsive to intervention NCI Symptomatic due to drop in ejection fraction responsive to intervention CTCAE_v5 Grade 3 Left Ventricular Systolic Dysfunction, CTCAE PT NCI Grade 3 Left ventricular systolic dysfunction PT CTCAE_v5 ctcae5:C55024 Severe with symptoms at rest or with minimal activity or exertion; intervention indicated; new onset of symptoms Severe with symptoms at rest or with minimal activity or exertion; intervention indicated; new onset of symptoms Grade 3 Myocarditis Grade 3 Myocarditis, CTCAE 10028606 C55024 Grade 3 Myocarditis Grade 3 Myocarditis Severe with symptoms at rest or with minimal activity or exertion; intervention indicated; new onset of symptoms NCI Severe with symptoms at rest or with minimal activity or exertion; intervention indicated; new onset of symptoms CTCAE_v5 Grade 3 Myocarditis PT CTCAE_v5 Grade 3 Myocarditis, CTCAE PT NCI ctcae5:C55026 Pericarditis with physiologic consequences (e.g., pericardial constriction) Pericarditis with physiologic consequences (e.g., pericardial constriction) Grade 3 Pericarditis Grade 3 Pericarditis, CTCAE 10034484 C55026 Grade 3 Pericarditis Grade 3 Pericarditis Pericarditis with physiologic consequences (e.g., pericardial constriction) NCI Pericarditis with physiologic consequences (e.g., pericardial constriction) CTCAE_v5 Grade 3 Pericarditis PT CTCAE_v5 Grade 3 Pericarditis, CTCAE PT NCI ctcae5:C55027 Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated Grade 3 Pulmonary Hypertension, CTCAE Grade 3 Pulmonary hypertension 10037400 C55027 Grade 3 Pulmonary hypertension Grade 3 Pulmonary hypertension Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated NCI Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated CTCAE_v5 Grade 3 Pulmonary Hypertension, CTCAE PT NCI Grade 3 Pulmonary hypertension PT CTCAE_v5 ctcae5:C55028 Symptomatic heart failure or other cardiac symptoms, responsive to intervention; new onset of symptoms Symptomatic heart failure or other cardiac symptoms, responsive to intervention; new onset of symptoms Grade 3 Restrictive Cardiomyopathy, CTCAE Grade 3 Restrictive cardiomyopathy 10038748 C55028 Grade 3 Restrictive cardiomyopathy Grade 3 Restrictive cardiomyopathy Symptomatic heart failure or other cardiac symptoms, responsive to intervention; new onset of symptoms NCI Symptomatic heart failure or other cardiac symptoms, responsive to intervention; new onset of symptoms CTCAE_v5 Grade 3 Restrictive Cardiomyopathy, CTCAE PT NCI Grade 3 Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55029 Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated Grade 3 Right Ventricular Dysfunction, CTCAE Grade 3 Right ventricular dysfunction 10058597 C55029 Grade 3 Right ventricular dysfunction Grade 3 Right ventricular dysfunction Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated NCI Severe symptoms, associated with hypoxia, right heart failure; oxygen indicated CTCAE_v5 Grade 3 Right Ventricular Dysfunction, CTCAE PT NCI Grade 3 Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55034 Adult and Pediatric: Life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit, hypertensive crisis); urgent intervention indicated Adult and Pediatric: Life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit, hypertensive crisis); urgent intervention indicated Grade 4 Hypertension Grade 4 Hypertension, CTCAE 10020772 C55034 Grade 4 Hypertension Grade 4 Hypertension Adult and Pediatric: Life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit, hypertensive crisis); urgent intervention indicated NCI Adult and Pediatric: Life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit, hypertensive crisis); urgent intervention indicated CTCAE_v5 Grade 4 Hypertension PT CTCAE_v5 Grade 4 Hypertension, CTCAE PT NCI ctcae5:C55035 Life-threatening consequences and urgent intervention indicated Life-threatening consequences and urgent intervention indicated Grade 4 Hypotension Grade 4 Hypotension, CTCAE 10021097 C55035 Grade 4 Hypotension Grade 4 Hypotension Life-threatening consequences and urgent intervention indicated NCI Life-threatening consequences and urgent intervention indicated CTCAE_v5 Grade 4 Hypotension PT CTCAE_v5 Grade 4 Hypotension, CTCAE PT NCI ctcae5:C55037 Refractory or poorly controlled heart failure due to drop in ejection fraction; intervention such as ventricular assist device, intravenous vasopressor support, or heart transplant indicated Refractory or poorly controlled heart failure due to drop in ejection fraction; intervention such as ventricular assist device, intravenous vasopressor support, or heart transplant indicated Grade 4 Left Ventricular Systolic Dysfunction, CTCAE Grade 4 Left ventricular systolic dysfunction 10069501 C55037 Grade 4 Left ventricular systolic dysfunction Grade 4 Left ventricular systolic dysfunction Refractory or poorly controlled heart failure due to drop in ejection fraction; intervention such as ventricular assist device, intravenous vasopressor support, or heart transplant indicated NCI Refractory or poorly controlled heart failure due to drop in ejection fraction; intervention such as ventricular assist device, intravenous vasopressor support, or heart transplant indicated CTCAE_v5 Grade 4 Left Ventricular Systolic Dysfunction, CTCAE PT NCI Grade 4 Left ventricular systolic dysfunction PT CTCAE_v5 ctcae5:C55038 Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) Grade 4 Myocarditis Grade 4 Myocarditis, CTCAE 10028606 C55038 Grade 4 Myocarditis Grade 4 Myocarditis Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) NCI Life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support) CTCAE_v5 Grade 4 Myocarditis PT CTCAE_v5 Grade 4 Myocarditis, CTCAE PT NCI ctcae5:C55040 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pericarditis Grade 4 Pericarditis, CTCAE 10034484 C55040 Grade 4 Pericarditis Grade 4 Pericarditis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pericarditis PT CTCAE_v5 Grade 4 Pericarditis, CTCAE PT NCI ctcae5:C55041 Life-threatening airway consequences; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway consequences; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Pulmonary Hypertension, CTCAE Grade 4 Pulmonary hypertension 10037400 C55041 Grade 4 Pulmonary hypertension Grade 4 Pulmonary hypertension Life-threatening airway consequences; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway consequences; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Pulmonary Hypertension, CTCAE PT NCI Grade 4 Pulmonary hypertension PT CTCAE_v5 ctcae5:C55042 Refractory heart failure or other poorly controlled cardiac symptoms Refractory heart failure or other poorly controlled cardiac symptoms Grade 4 Restrictive Cardiomyopathy, CTCAE Grade 4 Restrictive cardiomyopathy 10038748 C55042 Grade 4 Restrictive cardiomyopathy Grade 4 Restrictive cardiomyopathy Refractory heart failure or other poorly controlled cardiac symptoms NCI Refractory heart failure or other poorly controlled cardiac symptoms CTCAE_v5 Grade 4 Restrictive Cardiomyopathy, CTCAE PT NCI Grade 4 Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55043 Life-threatening consequences; urgent intervention indicated (e.g., ventricular assist device); heart transplant indicated Life-threatening consequences; urgent intervention indicated (e.g., ventricular assist device); heart transplant indicated Grade 4 Right Ventricular Dysfunction, CTCAE Grade 4 Right ventricular dysfunction 10058597 C55043 Grade 4 Right ventricular dysfunction Grade 4 Right ventricular dysfunction Life-threatening consequences; urgent intervention indicated (e.g., ventricular assist device); heart transplant indicated NCI Life-threatening consequences; urgent intervention indicated (e.g., ventricular assist device); heart transplant indicated CTCAE_v5 Grade 4 Right Ventricular Dysfunction, CTCAE PT NCI Grade 4 Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55048 Death Death Grade 5 Hypertension Grade 5 Hypertension, CTCAE 10020772 C55048 Grade 5 Hypertension Grade 5 Hypertension Death NCI Death CTCAE_v5 Grade 5 Hypertension PT CTCAE_v5 Grade 5 Hypertension, CTCAE PT NCI ctcae5:C55049 Death Death Grade 5 Hypotension Grade 5 Hypotension, CTCAE 10021097 C55049 Grade 5 Hypotension Grade 5 Hypotension Death NCI Death CTCAE_v5 Grade 5 Hypotension PT CTCAE_v5 Grade 5 Hypotension, CTCAE PT NCI ctcae5:C55051 Death Death Grade 5 Left Ventricular Systolic Dysfunction, CTCAE Grade 5 Left ventricular systolic dysfunction 10069501 C55051 Grade 5 Left ventricular systolic dysfunction Grade 5 Left ventricular systolic dysfunction Death NCI Death CTCAE_v5 Grade 5 Left Ventricular Systolic Dysfunction, CTCAE PT NCI Grade 5 Left ventricular systolic dysfunction PT CTCAE_v5 ctcae5:C55052 Death Death Grade 5 Myocarditis Grade 5 Myocarditis, CTCAE 10028606 C55052 Grade 5 Myocarditis Grade 5 Myocarditis Death NCI Death CTCAE_v5 Grade 5 Myocarditis PT CTCAE_v5 Grade 5 Myocarditis, CTCAE PT NCI ctcae5:C55054 Death Death Grade 5 Pericarditis Grade 5 Pericarditis, CTCAE 10034484 C55054 Grade 5 Pericarditis Grade 5 Pericarditis Death NCI Death CTCAE_v5 Grade 5 Pericarditis PT CTCAE_v5 Grade 5 Pericarditis, CTCAE PT NCI ctcae5:C55055 Death Death Grade 5 Pulmonary Hypertension, CTCAE Grade 5 Pulmonary hypertension 10037400 C55055 Grade 5 Pulmonary hypertension Grade 5 Pulmonary hypertension Death NCI Death CTCAE_v5 Grade 5 Pulmonary Hypertension, CTCAE PT NCI Grade 5 Pulmonary hypertension PT CTCAE_v5 ctcae5:C55056 Death Death Grade 5 Restrictive Cardiomyopathy, CTCAE Grade 5 Restrictive cardiomyopathy 10038748 C55056 Grade 5 Restrictive cardiomyopathy Grade 5 Restrictive cardiomyopathy Death NCI Death CTCAE_v5 Grade 5 Restrictive Cardiomyopathy, CTCAE PT NCI Grade 5 Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55057 Death Death Grade 5 Right Ventricular Dysfunction, CTCAE Grade 5 Right ventricular dysfunction 10058597 C55057 Grade 5 Right ventricular dysfunction Grade 5 Right ventricular dysfunction Death NCI Death CTCAE_v5 Grade 5 Right Ventricular Dysfunction, CTCAE PT NCI Grade 5 Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55060 A disorder characterized by a pathological increase in blood pressure. A disorder characterized by a pathological increase in blood pressure. Hypertension Hypertension, CTCAE 10020772 C55060 Hypertension Hypertension A disorder characterized by a pathological increase in blood pressure. NCI A disorder characterized by a pathological increase in blood pressure. CTCAE_v5 Hypertension PT CTCAE_v5 Hypertension, CTCAE PT NCI ctcae5:C55061 A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. Hypotension Hypotension, CTCAE 10021097 C55061 Hypotension Hypotension A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. NCI A disorder characterized by a blood pressure that is below the normal expected for an individual in a given environment. CTCAE_v5 Hypotension PT CTCAE_v5 Hypotension, CTCAE PT NCI ctcae5:C55067 A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). Pericarditis Pericarditis, CTCAE 10034484 C55067 Pericarditis Pericarditis A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). NCI A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart). CTCAE_v5 Pericarditis PT CTCAE_v5 Pericarditis, CTCAE PT NCI ctcae5:C55068 A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. Pulmonary Hypertension, CTCAE Pulmonary hypertension 10037400 C55068 Pulmonary hypertension Pulmonary hypertension A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. NCI A disorder characterized by an increase in pressure within the pulmonary circulation due to lung or heart disorder. CTCAE_v5 Pulmonary Hypertension, CTCAE PT NCI Pulmonary hypertension PT CTCAE_v5 ctcae5:C55069 A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. Restrictive Cardiomyopathy, CTCAE Restrictive cardiomyopathy 10038748 C55069 Restrictive cardiomyopathy Restrictive cardiomyopathy A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. NCI A disorder characterized by an inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and loses its flexibility. CTCAE_v5 Restrictive Cardiomyopathy, CTCAE PT NCI Restrictive cardiomyopathy PT CTCAE_v5 ctcae5:C55070 A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. Right Ventricular Dysfunction, CTCAE Right ventricular dysfunction 10058597 C55070 Right ventricular dysfunction Right ventricular dysfunction A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. NCI A disorder characterized by impairment of right ventricular function associated with low ejection fraction and a decrease in motility of the right ventricular wall. CTCAE_v5 Right Ventricular Dysfunction, CTCAE PT NCI Right ventricular dysfunction PT CTCAE_v5 ctcae5:C55178 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hemoglobinuria Grade 1 Hemoglobinuria, CTCAE 10019489 C55178 Grade 1 Hemoglobinuria Grade 1 Hemoglobinuria Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hemoglobinuria PT CTCAE_v5 Grade 1 Hemoglobinuria, CTCAE PT NCI ctcae5:C55220 1+ proteinuria; urinary protein > or = to ULN-<1.0 g/24 hrs 1+ proteinuria; urinary protein > or = to ULN-<1.0 g/24 hrs Grade 1 Proteinuria Grade 1 Proteinuria, CTCAE 10037032 C55220 Grade 1 Proteinuria Grade 1 Proteinuria 1+ proteinuria; urinary protein > or = to ULN-<1.0 g/24 hrs NCI 1+ proteinuria; urinary protein > or = to ULN-<1.0 g/24 hrs CTCAE_v5 Grade 1 Proteinuria PT CTCAE_v5 Grade 1 Proteinuria, CTCAE PT NCI ctcae5:C55221 Adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; Pediatric: Urine P/C (Protein/Creatinine) ratio 0.5-1.9 Adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; Pediatric: Urine P/C (Protein/Creatinine) ratio 0.5-1.9 Grade 2 Proteinuria Grade 2 Proteinuria, CTCAE 10037032 C55221 Grade 2 Proteinuria Grade 2 Proteinuria Adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; Pediatric: Urine P/C (Protein/Creatinine) ratio 0.5-1.9 NCI Adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; Pediatric: Urine P/C (Protein/Creatinine) ratio 0.5-1.9 CTCAE_v5 Grade 2 Proteinuria PT CTCAE_v5 Grade 2 Proteinuria, CTCAE PT NCI ctcae5:C55222 Adult: Urinary protein >=3.5 g/24 hrs; 4+ proteinuria; Pediatric: Urine P/C (Protein/Creatinine) ratio >1.9 Adult: Urinary protein >=3.5 g/24 hrs; 4+ proteinuria; Pediatric: Urine P/C (Protein/Creatinine) ratio >1.9 Grade 3 Proteinuria Grade 3 Proteinuria, CTCAE 10037032 C55222 Grade 3 Proteinuria Grade 3 Proteinuria Adult: Urinary protein >=3.5 g/24 hrs; 4+ proteinuria; Pediatric: Urine P/C (Protein/Creatinine) ratio >1.9 NCI Adult: Urinary protein >=3.5 g/24 hrs; 4+ proteinuria; Pediatric: Urine P/C (Protein/Creatinine) ratio >1.9 CTCAE_v5 Grade 3 Proteinuria PT CTCAE_v5 Grade 3 Proteinuria, CTCAE PT NCI ctcae5:C55255 Laboratory findings with no bleeding Laboratory findings with no bleeding Grade 2 Disseminated Intravascular Coagulation, CTCAE Grade 2 Disseminated intravascular coagulation 10013442 C55255 Grade 2 Disseminated intravascular coagulation Grade 2 Disseminated intravascular coagulation Laboratory findings with no bleeding NCI Laboratory findings with no bleeding CTCAE_v5 Grade 2 Disseminated Intravascular Coagulation, CTCAE PT NCI Grade 2 Disseminated intravascular coagulation PT CTCAE_v5 ctcae5:C55260 Laboratory findings and bleeding Laboratory findings and bleeding Grade 3 Disseminated Intravascular Coagulation, CTCAE Grade 3 Disseminated intravascular coagulation 10013442 C55260 Grade 3 Disseminated intravascular coagulation Grade 3 Disseminated intravascular coagulation Laboratory findings and bleeding NCI Laboratory findings and bleeding CTCAE_v5 Grade 3 Disseminated Intravascular Coagulation, CTCAE PT NCI Grade 3 Disseminated intravascular coagulation PT CTCAE_v5 ctcae5:C55266 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Disseminated Intravascular Coagulation, CTCAE Grade 4 Disseminated intravascular coagulation 10013442 C55266 Grade 4 Disseminated intravascular coagulation Grade 4 Disseminated intravascular coagulation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Disseminated Intravascular Coagulation, CTCAE PT NCI Grade 4 Disseminated intravascular coagulation PT CTCAE_v5 ctcae5:C55270 Death Death Grade 5 Disseminated Intravascular Coagulation, CTCAE Grade 5 Disseminated intravascular coagulation 10013442 C55270 Grade 5 Disseminated intravascular coagulation Grade 5 Disseminated intravascular coagulation Death NCI Death CTCAE_v5 Grade 5 Disseminated Intravascular Coagulation, CTCAE PT NCI Grade 5 Disseminated intravascular coagulation PT CTCAE_v5 ctcae5:C55273 A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. Disseminated Intravascular Coagulation, CTCAE Disseminated intravascular coagulation 10013442 C55273 Disseminated intravascular coagulation Disseminated intravascular coagulation A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. NCI A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors. CTCAE_v5 Disseminated Intravascular Coagulation, CTCAE PT NCI Disseminated intravascular coagulation PT CTCAE_v5 ctcae5:C55278 Death Death Grade 5 Death NOS Grade 5 Death NOS, CTCAE 10011914 C55278 Grade 5 Death NOS Grade 5 Death NOS Death NCI Death CTCAE_v5 Grade 5 Death NOS PT CTCAE_v5 Grade 5 Death NOS, CTCAE PT NCI ctcae5:C55280 Death Death Grade 5 Multi-Organ Failure, CTCAE Grade 5 Multi-organ failure 10028154 C55280 Grade 5 Multi-organ failure Grade 5 Multi-organ failure Death NCI Death CTCAE_v5 Grade 5 Multi-Organ Failure, CTCAE PT NCI Grade 5 Multi-organ failure PT CTCAE_v5 ctcae5:C55292 Fatigue relieved by rest Fatigue relieved by rest Grade 1 Fatigue Grade 1 Fatigue, CTCAE 10016256 C55292 Grade 1 Fatigue Grade 1 Fatigue Fatigue relieved by rest NCI Fatigue relieved by rest CTCAE_v5 Grade 1 Fatigue PT CTCAE_v5 Grade 1 Fatigue, CTCAE PT NCI ctcae5:C55294 Mild difficulty falling asleep, staying asleep or waking up early Mild difficulty falling asleep, staying asleep or waking up early Grade 1 Insomnia Grade 1 Insomnia, CTCAE 10022437 C55294 Grade 1 Insomnia Grade 1 Insomnia Mild difficulty falling asleep, staying asleep or waking up early NCI Mild difficulty falling asleep, staying asleep or waking up early CTCAE_v5 Grade 1 Insomnia PT CTCAE_v5 Grade 1 Insomnia, CTCAE PT NCI ctcae5:C55298 5-<10% from baseline 5-<10% from baseline Grade 1 Weight Gain, CTCAE Grade 1 Weight gain 10047896 C55298 Grade 1 Weight gain Grade 1 Weight gain 5-<10% from baseline NCI 5-<10% from baseline CTCAE_v5 Grade 1 Weight Gain, CTCAE PT NCI Grade 1 Weight gain PT CTCAE_v5 ctcae5:C55299 5 to <10% from baseline; intervention not indicated 5 to <10% from baseline; intervention not indicated Grade 1 Weight Loss, CTCAE Grade 1 Weight loss 10047900 C55299 Grade 1 Weight loss Grade 1 Weight loss 5 to <10% from baseline; intervention not indicated NCI 5 to <10% from baseline; intervention not indicated CTCAE_v5 Grade 1 Weight Loss, CTCAE PT NCI Grade 1 Weight loss PT CTCAE_v5 ctcae5:C55301 Fatigue not relieved by rest; limiting instrumental ADL Fatigue not relieved by rest; limiting instrumental ADL Grade 2 Fatigue Grade 2 Fatigue, CTCAE 10016256 C55301 Grade 2 Fatigue Grade 2 Fatigue Fatigue not relieved by rest; limiting instrumental ADL NCI Fatigue not relieved by rest; limiting instrumental ADL CTCAE_v5 Grade 2 Fatigue PT CTCAE_v5 Grade 2 Fatigue, CTCAE PT NCI ctcae5:C55303 35->32 degrees C; 95->89.6 degrees F 35->32 degrees C; 95->89.6 degrees F Grade 2 Hypothermia Grade 2 Hypothermia, CTCAE 10021113 C55303 Grade 2 Hypothermia Grade 2 Hypothermia 35->32 degrees C; 95->89.6 degrees F NCI 35->32 degrees C; 95->89.6 degrees F CTCAE_v5 Grade 2 Hypothermia PT CTCAE_v5 Grade 2 Hypothermia, CTCAE PT NCI ctcae5:C55304 Moderate difficulty falling asleep, staying asleep or waking up early Moderate difficulty falling asleep, staying asleep or waking up early Grade 2 Insomnia Grade 2 Insomnia, CTCAE 10022437 C55304 Grade 2 Insomnia Grade 2 Insomnia Moderate difficulty falling asleep, staying asleep or waking up early NCI Moderate difficulty falling asleep, staying asleep or waking up early CTCAE_v5 Grade 2 Insomnia PT CTCAE_v5 Grade 2 Insomnia, CTCAE PT NCI ctcae5:C55305 BMI 25-29.9 kg/m2 BMI 25-29.9 kg/m2 Grade 2 Obesity Grade 2 Obesity, CTCAE 10029883 C55305 Grade 2 Obesity Grade 2 Obesity BMI 25-29.9 kg/m2 NCI BMI 25-29.9 kg/m2 CTCAE_v5 Grade 2 Obesity PT CTCAE_v5 Grade 2 Obesity, CTCAE PT NCI ctcae5:C55309 10-<20% from baseline 10-<20% from baseline Grade 2 Weight Gain, CTCAE Grade 2 Weight gain 10047896 C55309 Grade 2 Weight gain Grade 2 Weight gain 10-<20% from baseline NCI 10-<20% from baseline CTCAE_v5 Grade 2 Weight Gain, CTCAE PT NCI Grade 2 Weight gain PT CTCAE_v5 ctcae5:C55310 10-<20% from baseline; nutritional support indicated 10-<20% from baseline; nutritional support indicated Grade 2 Weight Loss, CTCAE Grade 2 Weight loss 10047900 C55310 Grade 2 Weight loss Grade 2 Weight loss 10-<20% from baseline; nutritional support indicated NCI 10-<20% from baseline; nutritional support indicated CTCAE_v5 Grade 2 Weight Loss, CTCAE PT NCI Grade 2 Weight loss PT CTCAE_v5 ctcae5:C55311 Fatigue not relieved by rest, limiting self care ADL Fatigue not relieved by rest, limiting self care ADL Grade 3 Fatigue Grade 3 Fatigue, CTCAE 10016256 C55311 Grade 3 Fatigue Grade 3 Fatigue Fatigue not relieved by rest, limiting self care ADL NCI Fatigue not relieved by rest, limiting self care ADL CTCAE_v5 Grade 3 Fatigue PT CTCAE_v5 Grade 3 Fatigue, CTCAE PT NCI ctcae5:C55313 32->28 degrees C; 89.6->82.4 degrees F 32->28 degrees C; 89.6->82.4 degrees F Grade 3 Hypothermia Grade 3 Hypothermia, CTCAE 10021113 C55313 Grade 3 Hypothermia Grade 3 Hypothermia 32->28 degrees C; 89.6->82.4 degrees F NCI 32->28 degrees C; 89.6->82.4 degrees F CTCAE_v5 Grade 3 Hypothermia PT CTCAE_v5 Grade 3 Hypothermia, CTCAE PT NCI ctcae5:C55314 Severe difficulty in falling asleep, staying asleep or waking up early Severe difficulty in falling asleep, staying asleep or waking up early Grade 3 Insomnia Grade 3 Insomnia, CTCAE 10022437 C55314 Grade 3 Insomnia Grade 3 Insomnia Severe difficulty in falling asleep, staying asleep or waking up early NCI Severe difficulty in falling asleep, staying asleep or waking up early CTCAE_v5 Grade 3 Insomnia PT CTCAE_v5 Grade 3 Insomnia, CTCAE PT NCI ctcae5:C55315 BMI 30-39.9 kg/m2 BMI 30-39.9 kg/m2 Grade 3 Obesity Grade 3 Obesity, CTCAE 10029883 C55315 Grade 3 Obesity Grade 3 Obesity BMI 30-39.9 kg/m2 NCI BMI 30-39.9 kg/m2 CTCAE_v5 Grade 3 Obesity PT CTCAE_v5 Grade 3 Obesity, CTCAE PT NCI ctcae5:C55318 >=20% from baseline >=20% from baseline Grade 3 Weight Gain, CTCAE Grade 3 Weight gain 10047896 C55318 Grade 3 Weight gain Grade 3 Weight gain >=20% from baseline NCI >=20% from baseline CTCAE_v5 Grade 3 Weight Gain, CTCAE PT NCI Grade 3 Weight gain PT CTCAE_v5 ctcae5:C55319 >=20% from baseline; tube feeding or TPN indicated >=20% from baseline; tube feeding or TPN indicated Grade 3 Weight Loss, CTCAE Grade 3 Weight loss 10047900 C55319 Grade 3 Weight loss Grade 3 Weight loss >=20% from baseline; tube feeding or TPN indicated NCI >=20% from baseline; tube feeding or TPN indicated CTCAE_v5 Grade 3 Weight Loss, CTCAE PT NCI Grade 3 Weight loss PT CTCAE_v5 ctcae5:C55322 <=28 degrees C; 82.4 degrees F; life-threatening consequences (e.g., coma, hypotension, pulmonary edema, acidemia, ventricular fibrillation) <=28 degrees C; 82.4 degrees F; life-threatening consequences (e.g., coma, hypotension, pulmonary edema, acidemia, ventricular fibrillation) Grade 4 Hypothermia Grade 4 Hypothermia, CTCAE 10021113 C55322 Grade 4 Hypothermia Grade 4 Hypothermia <=28 degrees C; 82.4 degrees F; life-threatening consequences (e.g., coma, hypotension, pulmonary edema, acidemia, ventricular fibrillation) NCI <=28 degrees C; 82.4 degrees F; life-threatening consequences (e.g., coma, hypotension, pulmonary edema, acidemia, ventricular fibrillation) CTCAE_v5 Grade 4 Hypothermia PT CTCAE_v5 Grade 4 Hypothermia, CTCAE PT NCI ctcae5:C55324 BMI >=40 kg/m2 BMI >=40 kg/m2 Grade 4 Obesity Grade 4 Obesity, CTCAE 10029883 C55324 Grade 4 Obesity Grade 4 Obesity BMI >=40 kg/m2 NCI BMI >=40 kg/m2 CTCAE_v5 Grade 4 Obesity PT CTCAE_v5 Grade 4 Obesity, CTCAE PT NCI ctcae5:C55327 Death Death Grade 5 Hypothermia Grade 5 Hypothermia, CTCAE 10021113 C55327 Grade 5 Hypothermia Grade 5 Hypothermia Death NCI Death CTCAE_v5 Grade 5 Hypothermia PT CTCAE_v5 Grade 5 Hypothermia, CTCAE PT NCI ctcae5:C55332 A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. Hypothermia Hypothermia, CTCAE 10021113 C55332 Hypothermia Hypothermia A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. NCI A disorder characterized by an abnormally low body temperature. Treatment is required when the body temperature is 35C (95F) or below. CTCAE_v5 Hypothermia PT CTCAE_v5 Hypothermia, CTCAE PT NCI ctcae5:C55334 A disorder characterized by having a high amount of body fat. A disorder characterized by having a high amount of body fat. Obesity Obesity, CTCAE 10029883 C55334 Obesity Obesity A disorder characterized by having a high amount of body fat. NCI A disorder characterized by having a high amount of body fat. CTCAE_v5 Obesity PT CTCAE_v5 Obesity, CTCAE PT NCI ctcae5:C55338 A finding characterized by an unexpected or abnormal increase in overall body weight; for pediatrics, greater than the baseline growth curve. A finding characterized by an unexpected or abnormal increase in overall body weight; for pediatrics, greater than the baseline growth curve. Weight Gain, CTCAE Weight gain 10047896 C55338 Weight gain Weight gain A finding characterized by an unexpected or abnormal increase in overall body weight; for pediatrics, greater than the baseline growth curve. NCI A finding characterized by an unexpected or abnormal increase in overall body weight; for pediatrics, greater than the baseline growth curve. CTCAE_v5 Weight Gain, CTCAE PT NCI Weight gain PT CTCAE_v5 ctcae5:C55339 A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. Weight Loss, CTCAE Weight loss 10047900 C55339 Weight loss Weight loss A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. NCI A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve. CTCAE_v5 Weight Loss, CTCAE PT NCI Weight loss PT CTCAE_v5 ctcae5:C55340 A disorder characterized by cessation of breathing. A disorder characterized by cessation of breathing. Apnea Apnea, CTCAE 10002972 C55340 Apnea Apnea A disorder characterized by cessation of breathing. NCI A disorder characterized by cessation of breathing. CTCAE_v5 Apnea PT CTCAE_v5 Apnea, CTCAE PT NCI ctcae5:C55341 Present; medical intervention indicated Present; medical intervention indicated Grade 3 Apnea Grade 3 Apnea, CTCAE 10002972 C55341 Grade 3 Apnea Grade 3 Apnea Present; medical intervention indicated NCI Present; medical intervention indicated CTCAE_v5 Grade 3 Apnea PT CTCAE_v5 Grade 3 Apnea, CTCAE PT NCI ctcae5:C55342 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Apnea Grade 4 Apnea, CTCAE 10002972 C55342 Grade 4 Apnea Grade 4 Apnea Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Apnea PT CTCAE_v5 Grade 4 Apnea, CTCAE PT NCI ctcae5:C55343 Death Death Grade 5 Apnea Grade 5 Apnea, CTCAE 10002972 C55343 Grade 5 Apnea Grade 5 Apnea Death NCI Death CTCAE_v5 Grade 5 Apnea PT CTCAE_v5 Grade 5 Apnea, CTCAE PT NCI ctcae5:C55351 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ataxia Grade 1 Ataxia, CTCAE 10003591 C55351 Grade 1 Ataxia Grade 1 Ataxia Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ataxia PT CTCAE_v5 Grade 1 Ataxia, CTCAE PT NCI ctcae5:C55352 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Ataxia Grade 2 Ataxia, CTCAE 10003591 C55352 Grade 2 Ataxia Grade 2 Ataxia Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Ataxia PT CTCAE_v5 Grade 2 Ataxia, CTCAE PT NCI ctcae5:C55353 Severe symptoms; limiting self care ADL; mechanical assistance indicated Severe symptoms; limiting self care ADL; mechanical assistance indicated Grade 3 Ataxia Grade 3 Ataxia, CTCAE 10003591 C55353 Grade 3 Ataxia Grade 3 Ataxia Severe symptoms; limiting self care ADL; mechanical assistance indicated NCI Severe symptoms; limiting self care ADL; mechanical assistance indicated CTCAE_v5 Grade 3 Ataxia PT CTCAE_v5 Grade 3 Ataxia, CTCAE PT NCI ctcae5:C55357 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Brachial Plexopathy, CTCAE Grade 1 Brachial plexopathy 10065417 C55357 Grade 1 Brachial plexopathy Grade 1 Brachial plexopathy Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Brachial Plexopathy, CTCAE PT NCI Grade 1 Brachial plexopathy PT CTCAE_v5 ctcae5:C55358 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Brachial Plexopathy, CTCAE Grade 2 Brachial plexopathy 10065417 C55358 Grade 2 Brachial plexopathy Grade 2 Brachial plexopathy Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Brachial Plexopathy, CTCAE PT NCI Grade 2 Brachial plexopathy PT CTCAE_v5 ctcae5:C55359 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Brachial Plexopathy, CTCAE Grade 3 Brachial plexopathy 10065417 C55359 Grade 3 Brachial plexopathy Grade 3 Brachial plexopathy Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Brachial Plexopathy, CTCAE PT NCI Grade 3 Brachial plexopathy PT CTCAE_v5 ctcae5:C55374 Mild cognitive disability; not interfering with work/school/life performance; specialized educational services/devices not indicated Mild cognitive disability; not interfering with work/school/life performance; specialized educational services/devices not indicated Grade 1 Cognitive Disturbance, CTCAE Grade 1 Cognitive disturbance 10009845 C55374 Grade 1 Cognitive disturbance Grade 1 Cognitive disturbance Mild cognitive disability; not interfering with work/school/life performance; specialized educational services/devices not indicated NCI Mild cognitive disability; not interfering with work/school/life performance; specialized educational services/devices not indicated CTCAE_v5 Grade 1 Cognitive Disturbance, CTCAE PT NCI Grade 1 Cognitive disturbance PT CTCAE_v5 ctcae5:C55375 Moderate cognitive disability; interfering with work/school/life performance but capable of independent living; specialized resources on part time basis indicated Moderate cognitive disability; interfering with work/school/life performance but capable of independent living; specialized resources on part time basis indicated Grade 2 Cognitive Disturbance, CTCAE Grade 2 Cognitive disturbance 10009845 C55375 Grade 2 Cognitive disturbance Grade 2 Cognitive disturbance Moderate cognitive disability; interfering with work/school/life performance but capable of independent living; specialized resources on part time basis indicated NCI Moderate cognitive disability; interfering with work/school/life performance but capable of independent living; specialized resources on part time basis indicated CTCAE_v5 Grade 2 Cognitive Disturbance, CTCAE PT NCI Grade 2 Cognitive disturbance PT CTCAE_v5 ctcae5:C55376 Severe cognitive disability; significant impairment of work/school/life performance Severe cognitive disability; significant impairment of work/school/life performance Grade 3 Cognitive Disturbance, CTCAE Grade 3 Cognitive disturbance 10009845 C55376 Grade 3 Cognitive disturbance Grade 3 Cognitive disturbance Severe cognitive disability; significant impairment of work/school/life performance NCI Severe cognitive disability; significant impairment of work/school/life performance CTCAE_v5 Grade 3 Cognitive Disturbance, CTCAE PT NCI Grade 3 Cognitive disturbance PT CTCAE_v5 ctcae5:C55380 Mild disorientation Mild disorientation Grade 1 Confusion Grade 1 Confusion, CTCAE 10010300 C55380 Grade 1 Confusion Grade 1 Confusion Mild disorientation NCI Mild disorientation CTCAE_v5 Grade 1 Confusion PT CTCAE_v5 Grade 1 Confusion, CTCAE PT NCI ctcae5:C55381 Moderate disorientation; limiting instrumental ADL Moderate disorientation; limiting instrumental ADL Grade 2 Confusion Grade 2 Confusion, CTCAE 10010300 C55381 Grade 2 Confusion Grade 2 Confusion Moderate disorientation; limiting instrumental ADL NCI Moderate disorientation; limiting instrumental ADL CTCAE_v5 Grade 2 Confusion PT CTCAE_v5 Grade 2 Confusion, CTCAE PT NCI ctcae5:C55382 Severe disorientation; limiting self care ADL Severe disorientation; limiting self care ADL Grade 3 Confusion Grade 3 Confusion, CTCAE 10010300 C55382 Grade 3 Confusion Grade 3 Confusion Severe disorientation; limiting self care ADL NCI Severe disorientation; limiting self care ADL CTCAE_v5 Grade 3 Confusion PT CTCAE_v5 Grade 3 Confusion, CTCAE PT NCI ctcae5:C55383 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Confusion Grade 4 Confusion, CTCAE 10010300 C55383 Grade 4 Confusion Grade 4 Confusion Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Confusion PT CTCAE_v5 Grade 4 Confusion, CTCAE PT NCI ctcae5:C55386 Mild unsteadiness or sensation of movement Mild unsteadiness or sensation of movement Grade 1 Dizziness Grade 1 Dizziness, CTCAE 10013573 C55386 Grade 1 Dizziness Grade 1 Dizziness Mild unsteadiness or sensation of movement NCI Mild unsteadiness or sensation of movement CTCAE_v5 Grade 1 Dizziness PT CTCAE_v5 Grade 1 Dizziness, CTCAE PT NCI ctcae5:C55387 Moderate unsteadiness or sensation of movement; limiting instrumental ADL Moderate unsteadiness or sensation of movement; limiting instrumental ADL Grade 2 Dizziness Grade 2 Dizziness, CTCAE 10013573 C55387 Grade 2 Dizziness Grade 2 Dizziness Moderate unsteadiness or sensation of movement; limiting instrumental ADL NCI Moderate unsteadiness or sensation of movement; limiting instrumental ADL CTCAE_v5 Grade 2 Dizziness PT CTCAE_v5 Grade 2 Dizziness, CTCAE PT NCI ctcae5:C55388 Severe unsteadiness or sensation of movement; limiting self care ADL Severe unsteadiness or sensation of movement; limiting self care ADL Grade 3 Dizziness Grade 3 Dizziness, CTCAE 10013573 C55388 Grade 3 Dizziness Grade 3 Dizziness Severe unsteadiness or sensation of movement; limiting self care ADL NCI Severe unsteadiness or sensation of movement; limiting self care ADL CTCAE_v5 Grade 3 Dizziness PT CTCAE_v5 Grade 3 Dizziness, CTCAE PT NCI ctcae5:C55391 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Encephalopathy Grade 2 Encephalopathy, CTCAE 10014625 C55391 Grade 2 Encephalopathy Grade 2 Encephalopathy Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Encephalopathy PT CTCAE_v5 Grade 2 Encephalopathy, CTCAE PT NCI ctcae5:C55392 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Encephalopathy Grade 3 Encephalopathy, CTCAE 10014625 C55392 Grade 3 Encephalopathy Grade 3 Encephalopathy Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Encephalopathy PT CTCAE_v5 Grade 3 Encephalopathy, CTCAE PT NCI ctcae5:C55393 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Encephalopathy Grade 4 Encephalopathy, CTCAE 10014625 C55393 Grade 4 Encephalopathy Grade 4 Encephalopathy Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Encephalopathy PT CTCAE_v5 Grade 4 Encephalopathy, CTCAE PT NCI ctcae5:C55394 Death Death Grade 5 Encephalopathy Grade 5 Encephalopathy, CTCAE 10014625 C55394 Grade 5 Encephalopathy Grade 5 Encephalopathy Death NCI Death CTCAE_v5 Grade 5 Encephalopathy PT CTCAE_v5 Grade 5 Encephalopathy, CTCAE PT NCI ctcae5:C55401 A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. Hydrocephalus Hydrocephalus, CTCAE 10020508 C55401 Hydrocephalus Hydrocephalus A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. NCI A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain. CTCAE_v5 Hydrocephalus PT CTCAE_v5 Hydrocephalus, CTCAE PT NCI ctcae5:C55402 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hydrocephalus Grade 1 Hydrocephalus, CTCAE 10020508 C55402 Grade 1 Hydrocephalus Grade 1 Hydrocephalus Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hydrocephalus PT CTCAE_v5 Grade 1 Hydrocephalus, CTCAE PT NCI ctcae5:C55403 Moderate symptoms; intervention not indicated Moderate symptoms; intervention not indicated Grade 2 Hydrocephalus Grade 2 Hydrocephalus, CTCAE 10020508 C55403 Grade 2 Hydrocephalus Grade 2 Hydrocephalus Moderate symptoms; intervention not indicated NCI Moderate symptoms; intervention not indicated CTCAE_v5 Grade 2 Hydrocephalus PT CTCAE_v5 Grade 2 Hydrocephalus, CTCAE PT NCI ctcae5:C55404 Severe symptoms or neurological deficit; intervention indicated Severe symptoms or neurological deficit; intervention indicated Grade 3 Hydrocephalus Grade 3 Hydrocephalus, CTCAE 10020508 C55404 Grade 3 Hydrocephalus Grade 3 Hydrocephalus Severe symptoms or neurological deficit; intervention indicated NCI Severe symptoms or neurological deficit; intervention indicated CTCAE_v5 Grade 3 Hydrocephalus PT CTCAE_v5 Grade 3 Hydrocephalus, CTCAE PT NCI ctcae5:C55405 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hydrocephalus Grade 4 Hydrocephalus, CTCAE 10020508 C55405 Grade 4 Hydrocephalus Grade 4 Hydrocephalus Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hydrocephalus PT CTCAE_v5 Grade 4 Hydrocephalus, CTCAE PT NCI ctcae5:C55406 Death Death Grade 5 Hydrocephalus Grade 5 Hydrocephalus, CTCAE 10020508 C55406 Grade 5 Hydrocephalus Grade 5 Hydrocephalus Death NCI Death CTCAE_v5 Grade 5 Hydrocephalus PT CTCAE_v5 Grade 5 Hydrocephalus, CTCAE PT NCI ctcae5:C55428 Mild memory impairment Mild memory impairment Grade 1 Memory Impairment, CTCAE Grade 1 Memory impairment 10027175 C55428 Grade 1 Memory impairment Grade 1 Memory impairment Mild memory impairment NCI Mild memory impairment CTCAE_v5 Grade 1 Memory Impairment, CTCAE PT NCI Grade 1 Memory impairment PT CTCAE_v5 ctcae5:C55429 Moderate memory impairment; limiting instrumental ADL Moderate memory impairment; limiting instrumental ADL Grade 2 Memory Impairment, CTCAE Grade 2 Memory impairment 10027175 C55429 Grade 2 Memory impairment Grade 2 Memory impairment Moderate memory impairment; limiting instrumental ADL NCI Moderate memory impairment; limiting instrumental ADL CTCAE_v5 Grade 2 Memory Impairment, CTCAE PT NCI Grade 2 Memory impairment PT CTCAE_v5 ctcae5:C55430 Severe memory impairment; limiting self care ADL Severe memory impairment; limiting self care ADL Grade 3 Memory Impairment, CTCAE Grade 3 Memory impairment 10027175 C55430 Grade 3 Memory impairment Grade 3 Memory impairment Severe memory impairment; limiting self care ADL NCI Severe memory impairment; limiting self care ADL CTCAE_v5 Grade 3 Memory Impairment, CTCAE PT NCI Grade 3 Memory impairment PT CTCAE_v5 ctcae5:C55436 Mild mood alteration Mild mood alteration Grade 1 Agitation Grade 1 Agitation, CTCAE 10001497 C55436 Grade 1 Agitation Grade 1 Agitation Mild mood alteration NCI Mild mood alteration CTCAE_v5 Grade 1 Agitation PT CTCAE_v5 Grade 1 Agitation, CTCAE PT NCI ctcae5:C55437 Moderate mood alteration Moderate mood alteration Grade 2 Agitation Grade 2 Agitation, CTCAE 10001497 C55437 Grade 2 Agitation Grade 2 Agitation Moderate mood alteration NCI Moderate mood alteration CTCAE_v5 Grade 2 Agitation PT CTCAE_v5 Grade 2 Agitation, CTCAE PT NCI ctcae5:C55438 Severe agitation; hospitalization not indicated Severe agitation; hospitalization not indicated Grade 3 Agitation Grade 3 Agitation, CTCAE 10001497 C55438 Grade 3 Agitation Grade 3 Agitation Severe agitation; hospitalization not indicated NCI Severe agitation; hospitalization not indicated CTCAE_v5 Grade 3 Agitation PT CTCAE_v5 Grade 3 Agitation, CTCAE PT NCI ctcae5:C55439 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Agitation Grade 4 Agitation, CTCAE 10001497 C55439 Grade 4 Agitation Grade 4 Agitation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Agitation PT CTCAE_v5 Grade 4 Agitation, CTCAE PT NCI ctcae5:C55442 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Anxiety Grade 1 Anxiety, CTCAE 10002855 C55442 Grade 1 Anxiety Grade 1 Anxiety Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Anxiety PT CTCAE_v5 Grade 1 Anxiety, CTCAE PT NCI ctcae5:C55443 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Anxiety Grade 2 Anxiety, CTCAE 10002855 C55443 Grade 2 Anxiety Grade 2 Anxiety Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Anxiety PT CTCAE_v5 Grade 2 Anxiety, CTCAE PT NCI ctcae5:C55444 Severe symptoms; limiting self care ADL; hospitalization indicated Severe symptoms; limiting self care ADL; hospitalization indicated Grade 3 Anxiety Grade 3 Anxiety, CTCAE 10002855 C55444 Grade 3 Anxiety Grade 3 Anxiety Severe symptoms; limiting self care ADL; hospitalization indicated NCI Severe symptoms; limiting self care ADL; hospitalization indicated CTCAE_v5 Grade 3 Anxiety PT CTCAE_v5 Grade 3 Anxiety, CTCAE PT NCI ctcae5:C55445 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anxiety Grade 4 Anxiety, CTCAE 10002855 C55445 Grade 4 Anxiety Grade 4 Anxiety Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anxiety PT CTCAE_v5 Grade 4 Anxiety, CTCAE PT NCI ctcae5:C55447 A disorder characterized by melancholic feelings of grief or unhappiness. A disorder characterized by melancholic feelings of grief or unhappiness. Depression Depression, CTCAE 10012378 C55447 Depression Depression A disorder characterized by melancholic feelings of grief or unhappiness. NCI A disorder characterized by melancholic feelings of grief or unhappiness. CTCAE_v5 Depression PT CTCAE_v5 Depression, CTCAE PT NCI ctcae5:C55448 Mild depressive symptoms Mild depressive symptoms Grade 1 Depression Grade 1 Depression, CTCAE 10012378 C55448 Grade 1 Depression Grade 1 Depression Mild depressive symptoms NCI Mild depressive symptoms CTCAE_v5 Grade 1 Depression PT CTCAE_v5 Grade 1 Depression, CTCAE PT NCI ctcae5:C55449 Moderate depressive symptoms; limiting instrumental ADL Moderate depressive symptoms; limiting instrumental ADL Grade 2 Depression Grade 2 Depression, CTCAE 10012378 C55449 Grade 2 Depression Grade 2 Depression Moderate depressive symptoms; limiting instrumental ADL NCI Moderate depressive symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Depression PT CTCAE_v5 Grade 2 Depression, CTCAE PT NCI ctcae5:C55450 Severe depressive symptoms; limiting self care ADL; hospitalization not indicated Severe depressive symptoms; limiting self care ADL; hospitalization not indicated Grade 3 Depression Grade 3 Depression, CTCAE 10012378 C55450 Grade 3 Depression Grade 3 Depression Severe depressive symptoms; limiting self care ADL; hospitalization not indicated NCI Severe depressive symptoms; limiting self care ADL; hospitalization not indicated CTCAE_v5 Grade 3 Depression PT CTCAE_v5 Grade 3 Depression, CTCAE PT NCI ctcae5:C55451 Life-threatening consequences, threats of harm to self or others; hospitalization indicated Life-threatening consequences, threats of harm to self or others; hospitalization indicated Grade 4 Depression Grade 4 Depression, CTCAE 10012378 C55451 Grade 4 Depression Grade 4 Depression Life-threatening consequences, threats of harm to self or others; hospitalization indicated NCI Life-threatening consequences, threats of harm to self or others; hospitalization indicated CTCAE_v5 Grade 4 Depression PT CTCAE_v5 Grade 4 Depression, CTCAE PT NCI ctcae5:C55452 Death Death Grade 5 Depression Grade 5 Depression, CTCAE 10012378 C55452 Grade 5 Depression Grade 5 Depression Death NCI Death CTCAE_v5 Grade 5 Depression PT CTCAE_v5 Grade 5 Depression, CTCAE PT NCI ctcae5:C55454 Mild mood elevation Mild mood elevation Grade 1 Euphoria Grade 1 Euphoria, CTCAE 10015533 C55454 Grade 1 Euphoria Grade 1 Euphoria Mild mood elevation NCI Mild mood elevation CTCAE_v5 Grade 1 Euphoria PT CTCAE_v5 Grade 1 Euphoria, CTCAE PT NCI ctcae5:C55455 Moderate mood elevation Moderate mood elevation Grade 2 Euphoria Grade 2 Euphoria, CTCAE 10015533 C55455 Grade 2 Euphoria Grade 2 Euphoria Moderate mood elevation NCI Moderate mood elevation CTCAE_v5 Grade 2 Euphoria PT CTCAE_v5 Grade 2 Euphoria, CTCAE PT NCI ctcae5:C55456 Severe mood elevation (e.g., hypomania) Severe mood elevation (e.g., hypomania) Grade 3 Euphoria Grade 3 Euphoria, CTCAE 10015533 C55456 Grade 3 Euphoria Grade 3 Euphoria Severe mood elevation (e.g., hypomania) NCI Severe mood elevation (e.g., hypomania) CTCAE_v5 Grade 3 Euphoria PT CTCAE_v5 Grade 3 Euphoria, CTCAE PT NCI ctcae5:C55459 A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. Myelitis Myelitis, CTCAE 10028524 C55459 Myelitis Myelitis A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. NCI A disorder characterized by inflammation involving the spinal cord. Symptoms include weakness, paresthesia, sensory loss, marked discomfort and incontinence. CTCAE_v5 Myelitis PT CTCAE_v5 Myelitis, CTCAE PT NCI ctcae5:C55460 Asymptomatic; mild signs (e.g., Babinski's reflex or Lhermitte's sign) Asymptomatic; mild signs (e.g., Babinski's reflex or Lhermitte's sign) Grade 1 Myelitis Grade 1 Myelitis, CTCAE 10028524 C55460 Grade 1 Myelitis Grade 1 Myelitis Asymptomatic; mild signs (e.g., Babinski's reflex or Lhermitte's sign) NCI Asymptomatic; mild signs (e.g., Babinski's reflex or Lhermitte's sign) CTCAE_v5 Grade 1 Myelitis PT CTCAE_v5 Grade 1 Myelitis, CTCAE PT NCI ctcae5:C55461 Moderate weakness or sensory loss; limiting instrumental ADL Moderate weakness or sensory loss; limiting instrumental ADL Grade 2 Myelitis Grade 2 Myelitis, CTCAE 10028524 C55461 Grade 2 Myelitis Grade 2 Myelitis Moderate weakness or sensory loss; limiting instrumental ADL NCI Moderate weakness or sensory loss; limiting instrumental ADL CTCAE_v5 Grade 2 Myelitis PT CTCAE_v5 Grade 2 Myelitis, CTCAE PT NCI ctcae5:C55462 Severe weakness or sensory loss; limiting self care ADL Severe weakness or sensory loss; limiting self care ADL Grade 3 Myelitis Grade 3 Myelitis, CTCAE 10028524 C55462 Grade 3 Myelitis Grade 3 Myelitis Severe weakness or sensory loss; limiting self care ADL NCI Severe weakness or sensory loss; limiting self care ADL CTCAE_v5 Grade 3 Myelitis PT CTCAE_v5 Grade 3 Myelitis, CTCAE PT NCI ctcae5:C55463 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Myelitis Grade 4 Myelitis, CTCAE 10028524 C55463 Grade 4 Myelitis Grade 4 Myelitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Myelitis PT CTCAE_v5 Grade 4 Myelitis, CTCAE PT NCI ctcae5:C55464 Death Death Grade 5 Myelitis Grade 5 Myelitis, CTCAE 10028524 C55464 Grade 5 Myelitis Grade 5 Myelitis Death NCI Death CTCAE_v5 Grade 5 Myelitis PT CTCAE_v5 Grade 5 Myelitis, CTCAE PT NCI ctcae5:C55579 Brief generalized seizure Brief generalized seizure Grade 2 Seizure Grade 2 Seizure, CTCAE 10039906 C55579 Grade 2 Seizure Grade 2 Seizure Brief generalized seizure NCI Brief generalized seizure CTCAE_v5 Grade 2 Seizure PT CTCAE_v5 Grade 2 Seizure, CTCAE PT NCI ctcae5:C55580 New onset seizures (partial or generalized); multiple seizures despite medical intervention New onset seizures (partial or generalized); multiple seizures despite medical intervention Grade 3 Seizure Grade 3 Seizure, CTCAE 10039906 C55580 Grade 3 Seizure Grade 3 Seizure New onset seizures (partial or generalized); multiple seizures despite medical intervention NCI New onset seizures (partial or generalized); multiple seizures despite medical intervention CTCAE_v5 Grade 3 Seizure PT CTCAE_v5 Grade 3 Seizure, CTCAE PT NCI ctcae5:C55581 Life-threatening consequences; prolonged repetitive seizures Life-threatening consequences; prolonged repetitive seizures Grade 4 Seizure Grade 4 Seizure, CTCAE 10039906 C55581 Grade 4 Seizure Grade 4 Seizure Life-threatening consequences; prolonged repetitive seizures NCI Life-threatening consequences; prolonged repetitive seizures CTCAE_v5 Grade 4 Seizure PT CTCAE_v5 Grade 4 Seizure, CTCAE PT NCI ctcae5:C55582 Death Death Grade 5 Seizure Grade 5 Seizure, CTCAE 10039906 C55582 Grade 5 Seizure Grade 5 Seizure Death NCI Death CTCAE_v5 Grade 5 Seizure PT CTCAE_v5 Grade 5 Seizure, CTCAE PT NCI ctcae5:C55593 Fainting; orthostatic collapse Fainting; orthostatic collapse Grade 3 Syncope Grade 3 Syncope, CTCAE 10042772 C55593 Grade 3 Syncope Grade 3 Syncope Fainting; orthostatic collapse NCI Fainting; orthostatic collapse CTCAE_v5 Grade 3 Syncope PT CTCAE_v5 Grade 3 Syncope, CTCAE PT NCI ctcae5:C55597 Mild symptoms Mild symptoms Grade 1 Tremor Grade 1 Tremor, CTCAE 10044565 C55597 Grade 1 Tremor Grade 1 Tremor Mild symptoms NCI Mild symptoms CTCAE_v5 Grade 1 Tremor PT CTCAE_v5 Grade 1 Tremor, CTCAE PT NCI ctcae5:C55598 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Tremor Grade 2 Tremor, CTCAE 10044565 C55598 Grade 2 Tremor Grade 2 Tremor Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Tremor PT CTCAE_v5 Grade 2 Tremor, CTCAE PT NCI ctcae5:C55599 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Tremor Grade 3 Tremor, CTCAE 10044565 C55599 Grade 3 Tremor Grade 3 Tremor Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Tremor PT CTCAE_v5 Grade 3 Tremor, CTCAE PT NCI ctcae5:C55615 A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. Erectile Dysfunction, CTCAE Erectile dysfunction 10061461 C55615 Erectile dysfunction Erectile dysfunction A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. NCI A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. CTCAE_v5 Erectile Dysfunction, CTCAE PT NCI Erectile dysfunction PT CTCAE_v5 ctcae5:C55616 Decrease in erectile function (frequency or rigidity of erections) but intervention not indicated (e.g., medication or use of mechanical device, penile pump) Decrease in erectile function (frequency or rigidity of erections) but intervention not indicated (e.g., medication or use of mechanical device, penile pump) Grade 1 Erectile Dysfunction, CTCAE Grade 1 Erectile dysfunction 10061461 C55616 Grade 1 Erectile dysfunction Grade 1 Erectile dysfunction Decrease in erectile function (frequency or rigidity of erections) but intervention not indicated (e.g., medication or use of mechanical device, penile pump) NCI Decrease in erectile function (frequency or rigidity of erections) but intervention not indicated (e.g., medication or use of mechanical device, penile pump) CTCAE_v5 Grade 1 Erectile Dysfunction, CTCAE PT NCI Grade 1 Erectile dysfunction PT CTCAE_v5 ctcae5:C55617 Decrease in erectile function (frequency/rigidity of erections), erectile intervention indicated, (e.g., medication or mechanical devices such as penile pump) Decrease in erectile function (frequency/rigidity of erections), erectile intervention indicated, (e.g., medication or mechanical devices such as penile pump) Grade 2 Erectile Dysfunction, CTCAE Grade 2 Erectile dysfunction 10061461 C55617 Grade 2 Erectile dysfunction Grade 2 Erectile dysfunction Decrease in erectile function (frequency/rigidity of erections), erectile intervention indicated, (e.g., medication or mechanical devices such as penile pump) NCI Decrease in erectile function (frequency/rigidity of erections), erectile intervention indicated, (e.g., medication or mechanical devices such as penile pump) CTCAE_v5 Grade 2 Erectile Dysfunction, CTCAE PT NCI Grade 2 Erectile dysfunction PT CTCAE_v5 ctcae5:C55618 Decrease in erectile function (frequency/rigidity of erections) but erectile intervention not helpful (e.g., medication or mechanical devices such as penile pump); placement of a permanent penile prosthesis indicated (not previously present) Decrease in erectile function (frequency/rigidity of erections) but erectile intervention not helpful (e.g., medication or mechanical devices such as penile pump); placement of a permanent penile prosthesis indicated (not previously present) Grade 3 Erectile Dysfunction, CTCAE Grade 3 Erectile dysfunction 10061461 C55618 Grade 3 Erectile dysfunction Grade 3 Erectile dysfunction Decrease in erectile function (frequency/rigidity of erections) but erectile intervention not helpful (e.g., medication or mechanical devices such as penile pump); placement of a permanent penile prosthesis indicated (not previously present) NCI Decrease in erectile function (frequency/rigidity of erections) but erectile intervention not helpful (e.g., medication or mechanical devices such as penile pump); placement of a permanent penile prosthesis indicated (not previously present) CTCAE_v5 Grade 3 Erectile Dysfunction, CTCAE PT NCI Grade 3 Erectile dysfunction PT CTCAE_v5 ctcae5:C55620 Symptomatic (e.g., pain or psychosocial impact) Symptomatic (e.g., pain or psychosocial impact) Grade 2 Gynecomastia Grade 2 Gynecomastia, CTCAE 10018801 C55620 Grade 2 Gynecomastia Grade 2 Gynecomastia Symptomatic (e.g., pain or psychosocial impact) NCI Symptomatic (e.g., pain or psychosocial impact) CTCAE_v5 Grade 2 Gynecomastia PT CTCAE_v5 Grade 2 Gynecomastia, CTCAE PT NCI ctcae5:C55621 Severe symptoms; elective operative intervention indicated Severe symptoms; elective operative intervention indicated Grade 3 Gynecomastia Grade 3 Gynecomastia, CTCAE 10018801 C55621 Grade 3 Gynecomastia Grade 3 Gynecomastia Severe symptoms; elective operative intervention indicated NCI Severe symptoms; elective operative intervention indicated CTCAE_v5 Grade 3 Gynecomastia PT CTCAE_v5 Grade 3 Gynecomastia, CTCAE PT NCI ctcae5:C55646 Mild vaginal dryness not interfering with sexual function Mild vaginal dryness not interfering with sexual function Grade 1 Vaginal Dryness, CTCAE Grade 1 Vaginal dryness 10046904 C55646 Grade 1 Vaginal dryness Grade 1 Vaginal dryness Mild vaginal dryness not interfering with sexual function NCI Mild vaginal dryness not interfering with sexual function CTCAE_v5 Grade 1 Vaginal Dryness, CTCAE PT NCI Grade 1 Vaginal dryness PT CTCAE_v5 ctcae5:C55647 Moderate vaginal dryness interfering with sexual function or causing frequent discomfort Moderate vaginal dryness interfering with sexual function or causing frequent discomfort Grade 2 Vaginal Dryness, CTCAE Grade 2 Vaginal dryness 10046904 C55647 Grade 2 Vaginal dryness Grade 2 Vaginal dryness Moderate vaginal dryness interfering with sexual function or causing frequent discomfort NCI Moderate vaginal dryness interfering with sexual function or causing frequent discomfort CTCAE_v5 Grade 2 Vaginal Dryness, CTCAE PT NCI Grade 2 Vaginal dryness PT CTCAE_v5 ctcae5:C55705 A disorder characterized by a cystic lesion containing lymph. A disorder characterized by a cystic lesion containing lymph. Lymphocele Lymphocele, CTCAE 10048642 C55705 Lymphocele Lymphocele A disorder characterized by a cystic lesion containing lymph. NCI A disorder characterized by a cystic lesion containing lymph. CTCAE_v5 Lymphocele PT CTCAE_v5 Lymphocele, CTCAE PT NCI ctcae5:C55706 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Lymphocele Grade 1 Lymphocele, CTCAE 10048642 C55706 Grade 1 Lymphocele Grade 1 Lymphocele Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Lymphocele PT CTCAE_v5 Grade 1 Lymphocele, CTCAE PT NCI ctcae5:C55707 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Lymphocele Grade 2 Lymphocele, CTCAE 10048642 C55707 Grade 2 Lymphocele Grade 2 Lymphocele Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Lymphocele PT CTCAE_v5 Grade 2 Lymphocele, CTCAE PT NCI ctcae5:C55708 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Lymphocele Grade 3 Lymphocele, CTCAE 10048642 C55708 Grade 3 Lymphocele Grade 3 Lymphocele Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Lymphocele PT CTCAE_v5 Grade 3 Lymphocele, CTCAE PT NCI ctcae5:C55724 No breast development by age 13 yrs for females; testes volume of <3 cc or no Tanner Stage 2 development by age 14.5 yrs for males No breast development by age 13 yrs for females; testes volume of <3 cc or no Tanner Stage 2 development by age 14.5 yrs for males Grade 2 Delayed Puberty, CTCAE Grade 2 Delayed puberty 10012205 C55724 Grade 2 Delayed puberty Grade 2 Delayed puberty No breast development by age 13 yrs for females; testes volume of <3 cc or no Tanner Stage 2 development by age 14.5 yrs for males NCI No breast development by age 13 yrs for females; testes volume of <3 cc or no Tanner Stage 2 development by age 14.5 yrs for males CTCAE_v5 Grade 2 Delayed Puberty, CTCAE PT NCI Grade 2 Delayed puberty PT CTCAE_v5 ctcae5:C55725 Physical signs and biochemical markers of puberty for females <8 years and males <9 years Physical signs and biochemical markers of puberty for females <8 years and males <9 years Grade 2 Precocious Puberty, CTCAE Grade 2 Precocious puberty 10058084 C55725 Grade 2 Precocious puberty Grade 2 Precocious puberty Physical signs and biochemical markers of puberty for females <8 years and males <9 years NCI Physical signs and biochemical markers of puberty for females <8 years and males <9 years CTCAE_v5 Grade 2 Precocious Puberty, CTCAE PT NCI Grade 2 Precocious puberty PT CTCAE_v5 ctcae5:C55732 No breast development by age 14 yrs for females; no increase in testes volume or no Tanner Stage 2 by age 16 yrs for males; hormone replacement indicated No breast development by age 14 yrs for females; no increase in testes volume or no Tanner Stage 2 by age 16 yrs for males; hormone replacement indicated Grade 3 Delayed Puberty, CTCAE Grade 3 Delayed puberty 10012205 C55732 Grade 3 Delayed puberty Grade 3 Delayed puberty No breast development by age 14 yrs for females; no increase in testes volume or no Tanner Stage 2 by age 16 yrs for males; hormone replacement indicated NCI No breast development by age 14 yrs for females; no increase in testes volume or no Tanner Stage 2 by age 16 yrs for males; hormone replacement indicated CTCAE_v5 Grade 3 Delayed Puberty, CTCAE PT NCI Grade 3 Delayed puberty PT CTCAE_v5 ctcae5:C55742 A disorder characterized by unusually late sexual maturity. A disorder characterized by unusually late sexual maturity. Delayed Puberty, CTCAE Delayed puberty 10012205 C55742 Delayed puberty Delayed puberty A disorder characterized by unusually late sexual maturity. NCI A disorder characterized by unusually late sexual maturity. CTCAE_v5 Delayed Puberty, CTCAE PT NCI Delayed puberty PT CTCAE_v5 ctcae5:C55748 A disorder characterized by the adrenal cortex not producing enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. A disorder characterized by the adrenal cortex not producing enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. Adrenal Insufficiency, CTCAE Adrenal insufficiency 10001367 C55748 Adrenal insufficiency Adrenal insufficiency A disorder characterized by the adrenal cortex not producing enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. NCI A disorder characterized by the adrenal cortex not producing enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison's disease or primary adrenal insufficiency. CTCAE_v5 Adrenal Insufficiency, CTCAE PT NCI Adrenal insufficiency PT CTCAE_v5 ctcae5:C55749 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Adrenal Insufficiency, CTCAE Grade 1 Adrenal insufficiency 10001367 C55749 Grade 1 Adrenal insufficiency Grade 1 Adrenal insufficiency Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Adrenal Insufficiency, CTCAE PT NCI Grade 1 Adrenal insufficiency PT CTCAE_v5 ctcae5:C55761 Moderate symptoms; medical intervention indicated Moderate symptoms; medical intervention indicated Grade 2 Adrenal Insufficiency, CTCAE Grade 2 Adrenal insufficiency 10001367 C55761 Grade 2 Adrenal insufficiency Grade 2 Adrenal insufficiency Moderate symptoms; medical intervention indicated NCI Moderate symptoms; medical intervention indicated CTCAE_v5 Grade 2 Adrenal Insufficiency, CTCAE PT NCI Grade 2 Adrenal insufficiency PT CTCAE_v5 ctcae5:C55774 Severe symptoms; hospitalization indicated Severe symptoms; hospitalization indicated Grade 3 Adrenal Insufficiency, CTCAE Grade 3 Adrenal insufficiency 10001367 C55774 Grade 3 Adrenal insufficiency Grade 3 Adrenal insufficiency Severe symptoms; hospitalization indicated NCI Severe symptoms; hospitalization indicated CTCAE_v5 Grade 3 Adrenal Insufficiency, CTCAE PT NCI Grade 3 Adrenal insufficiency PT CTCAE_v5 ctcae5:C55786 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Adrenal Insufficiency, CTCAE Grade 4 Adrenal insufficiency 10001367 C55786 Grade 4 Adrenal insufficiency Grade 4 Adrenal insufficiency Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Adrenal Insufficiency, CTCAE PT NCI Grade 4 Adrenal insufficiency PT CTCAE_v5 ctcae5:C55793 Death Death Grade 5 Adrenal Insufficiency, CTCAE Grade 5 Adrenal insufficiency 10001367 C55793 Grade 5 Adrenal insufficiency Grade 5 Adrenal insufficiency Death NCI Death CTCAE_v5 Grade 5 Adrenal Insufficiency, CTCAE PT NCI Grade 5 Adrenal insufficiency PT CTCAE_v5 ctcae5:C55831 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Cataract Grade 1 Cataract, CTCAE 10007739 C55831 Grade 1 Cataract Grade 1 Cataract Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Cataract PT CTCAE_v5 Grade 1 Cataract, CTCAE PT NCI ctcae5:C55832 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); glare symptoms affecting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); glare symptoms affecting instrumental ADL Grade 2 Cataract Grade 2 Cataract, CTCAE 10007739 C55832 Grade 2 Cataract Grade 2 Cataract Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); glare symptoms affecting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); glare symptoms affecting instrumental ADL CTCAE_v5 Grade 2 Cataract PT CTCAE_v5 Grade 2 Cataract, CTCAE PT NCI ctcae5:C55833 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Cataract Grade 3 Cataract, CTCAE 10007739 C55833 Grade 3 Cataract Grade 3 Cataract Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Cataract PT CTCAE_v5 Grade 3 Cataract, CTCAE PT NCI ctcae5:C55842 A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. Glaucoma Glaucoma, CTCAE 10018304 C55842 Glaucoma Glaucoma A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. NCI A disorder characterized by an increase in pressure in the eyeball due to obstruction of the aqueous humor outflow. CTCAE_v5 Glaucoma PT CTCAE_v5 Glaucoma, CTCAE PT NCI ctcae5:C55843 Less than 8 mmHg of elevated intraocular pressure (EIOP); no visual field deficit Less than 8 mmHg of elevated intraocular pressure (EIOP); no visual field deficit Grade 1 Glaucoma Grade 1 Glaucoma, CTCAE 10018304 C55843 Grade 1 Glaucoma Grade 1 Glaucoma Less than 8 mmHg of elevated intraocular pressure (EIOP); no visual field deficit NCI Less than 8 mmHg of elevated intraocular pressure (EIOP); no visual field deficit CTCAE_v5 Grade 1 Glaucoma PT CTCAE_v5 Grade 1 Glaucoma, CTCAE PT NCI ctcae5:C55844 EIOP which can be reduced to 21 mmHg or under with topical medications and no visual field deficit EIOP which can be reduced to 21 mmHg or under with topical medications and no visual field deficit Grade 2 Glaucoma Grade 2 Glaucoma, CTCAE 10018304 C55844 Grade 2 Glaucoma Grade 2 Glaucoma EIOP which can be reduced to 21 mmHg or under with topical medications and no visual field deficit NCI EIOP which can be reduced to 21 mmHg or under with topical medications and no visual field deficit CTCAE_v5 Grade 2 Glaucoma PT CTCAE_v5 Grade 2 Glaucoma, CTCAE PT NCI ctcae5:C55845 EIOP causing visual field deficits EIOP causing visual field deficits Grade 3 Glaucoma Grade 3 Glaucoma, CTCAE 10018304 C55845 Grade 3 Glaucoma Grade 3 Glaucoma EIOP causing visual field deficits NCI EIOP causing visual field deficits CTCAE_v5 Grade 3 Glaucoma PT CTCAE_v5 Grade 3 Glaucoma, CTCAE PT NCI ctcae5:C55846 Visual field deficit within the central 10 degrees of the visual field in the affected eye Visual field deficit within the central 10 degrees of the visual field in the affected eye Grade 4 Glaucoma Grade 4 Glaucoma, CTCAE 10018304 C55846 Grade 4 Glaucoma Grade 4 Glaucoma Visual field deficit within the central 10 degrees of the visual field in the affected eye NCI Visual field deficit within the central 10 degrees of the visual field in the affected eye CTCAE_v5 Grade 4 Glaucoma PT CTCAE_v5 Grade 4 Glaucoma, CTCAE PT NCI ctcae5:C55847 A disorder characterized by inflammation to the cornea of the eye. A disorder characterized by inflammation to the cornea of the eye. Keratitis Keratitis, CTCAE 10023332 C55847 Keratitis Keratitis A disorder characterized by inflammation to the cornea of the eye. NCI A disorder characterized by inflammation to the cornea of the eye. CTCAE_v5 Keratitis PT CTCAE_v5 Keratitis, CTCAE PT NCI ctcae5:C55848 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Keratitis Grade 1 Keratitis, CTCAE 10023332 C55848 Grade 1 Keratitis Grade 1 Keratitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Keratitis PT CTCAE_v5 Grade 1 Keratitis, CTCAE PT NCI ctcae5:C55849 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) Grade 2 Keratitis Grade 2 Keratitis, CTCAE 10023332 C55849 Grade 2 Keratitis Grade 2 Keratitis Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline) CTCAE_v5 Grade 2 Keratitis PT CTCAE_v5 Grade 2 Keratitis, CTCAE PT NCI ctcae5:C55850 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); corneal ulcer; limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); corneal ulcer; limiting self care ADL Grade 3 Keratitis Grade 3 Keratitis, CTCAE 10023332 C55850 Grade 3 Keratitis Grade 3 Keratitis Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); corneal ulcer; limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); corneal ulcer; limiting self care ADL CTCAE_v5 Grade 3 Keratitis PT CTCAE_v5 Grade 3 Keratitis, CTCAE PT NCI ctcae5:C55851 Perforation; best corrected visual acuity of 20/200 or worse in the affected eye Perforation; best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Keratitis Grade 4 Keratitis, CTCAE 10023332 C55851 Grade 4 Keratitis Grade 4 Keratitis Perforation; best corrected visual acuity of 20/200 or worse in the affected eye NCI Perforation; best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Keratitis PT CTCAE_v5 Grade 4 Keratitis, CTCAE PT NCI ctcae5:C55859 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Nystagmus Grade 2 Nystagmus, CTCAE 10029864 C55859 Grade 2 Nystagmus Grade 2 Nystagmus Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Nystagmus PT CTCAE_v5 Grade 2 Nystagmus, CTCAE PT NCI ctcae5:C55860 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Nystagmus Grade 3 Nystagmus, CTCAE 10029864 C55860 Grade 3 Nystagmus Grade 3 Nystagmus Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Nystagmus PT CTCAE_v5 Grade 3 Nystagmus, CTCAE PT NCI ctcae5:C55889 Macular sparing rhegmatogenous detachment Macular sparing rhegmatogenous detachment Grade 3 Retinal Detachment, CTCAE Grade 3 Retinal detachment 10038848 C55889 Grade 3 Retinal detachment Grade 3 Retinal detachment Macular sparing rhegmatogenous detachment NCI Macular sparing rhegmatogenous detachment CTCAE_v5 Grade 3 Retinal Detachment, CTCAE PT NCI Grade 3 Retinal detachment PT CTCAE_v5 ctcae5:C55890 Macula-off rhegmatogenous retinal detachment Macula-off rhegmatogenous retinal detachment Grade 4 Retinal Detachment, CTCAE Grade 4 Retinal detachment 10038848 C55890 Grade 4 Retinal detachment Grade 4 Retinal detachment Macula-off rhegmatogenous retinal detachment NCI Macula-off rhegmatogenous retinal detachment CTCAE_v5 Grade 4 Retinal Detachment, CTCAE PT NCI Grade 4 Retinal detachment PT CTCAE_v5 ctcae5:C55891 A disorder involving the retina. A disorder involving the retina. Retinopathy Retinopathy, CTCAE 10038923 C55891 Retinopathy Retinopathy A disorder involving the retina. NCI A disorder involving the retina. CTCAE_v5 Retinopathy PT CTCAE_v5 Retinopathy, CTCAE PT NCI ctcae5:C55892 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Retinopathy Grade 1 Retinopathy, CTCAE 10038923 C55892 Grade 1 Retinopathy Grade 1 Retinopathy Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Retinopathy PT CTCAE_v5 Grade 1 Retinopathy, CTCAE PT NCI ctcae5:C55893 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Grade 2 Retinopathy Grade 2 Retinopathy, CTCAE 10038923 C55893 Grade 2 Retinopathy Grade 2 Retinopathy Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL CTCAE_v5 Grade 2 Retinopathy PT CTCAE_v5 Grade 2 Retinopathy, CTCAE PT NCI ctcae5:C55894 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Retinopathy Grade 3 Retinopathy, CTCAE 10038923 C55894 Grade 3 Retinopathy Grade 3 Retinopathy Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Retinopathy PT CTCAE_v5 Grade 3 Retinopathy, CTCAE PT NCI ctcae5:C55895 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Retinopathy Grade 4 Retinopathy, CTCAE 10038923 C55895 Grade 4 Retinopathy Grade 4 Retinopathy Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Retinopathy PT CTCAE_v5 Grade 4 Retinopathy, CTCAE PT NCI ctcae5:C55901 A disorder characterized by inflammation to the uvea of the eye. A disorder characterized by inflammation to the uvea of the eye. Uveitis Uveitis, CTCAE 10046851 C55901 Uveitis Uveitis A disorder characterized by inflammation to the uvea of the eye. NCI A disorder characterized by inflammation to the uvea of the eye. CTCAE_v5 Uveitis PT CTCAE_v5 Uveitis, CTCAE PT NCI ctcae5:C55902 Anterior uveitis with trace cells Anterior uveitis with trace cells Grade 1 Uveitis Grade 1 Uveitis, CTCAE 10046851 C55902 Grade 1 Uveitis Grade 1 Uveitis Anterior uveitis with trace cells NCI Anterior uveitis with trace cells CTCAE_v5 Grade 1 Uveitis PT CTCAE_v5 Grade 1 Uveitis, CTCAE PT NCI ctcae5:C55903 Anterior uveitis with 1+ or 2+ cells Anterior uveitis with 1+ or 2+ cells Grade 2 Uveitis Grade 2 Uveitis, CTCAE 10046851 C55903 Grade 2 Uveitis Grade 2 Uveitis Anterior uveitis with 1+ or 2+ cells NCI Anterior uveitis with 1+ or 2+ cells CTCAE_v5 Grade 2 Uveitis PT CTCAE_v5 Grade 2 Uveitis, CTCAE PT NCI ctcae5:C55904 Anterior uveitis with 3+ or greater cells; intermediate posterior or pan-uveitis Anterior uveitis with 3+ or greater cells; intermediate posterior or pan-uveitis Grade 3 Uveitis Grade 3 Uveitis, CTCAE 10046851 C55904 Grade 3 Uveitis Grade 3 Uveitis Anterior uveitis with 3+ or greater cells; intermediate posterior or pan-uveitis NCI Anterior uveitis with 3+ or greater cells; intermediate posterior or pan-uveitis CTCAE_v5 Grade 3 Uveitis PT CTCAE_v5 Grade 3 Uveitis, CTCAE PT NCI ctcae5:C55905 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Uveitis Grade 4 Uveitis, CTCAE 10046851 C55905 Grade 4 Uveitis Grade 4 Uveitis Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Uveitis PT CTCAE_v5 Grade 4 Uveitis, CTCAE PT NCI ctcae5:C55906 A disorder characterized by visual perception of unclear or fuzzy images. A disorder characterized by visual perception of unclear or fuzzy images. Blurred Vision, CTCAE Blurred vision 10005886 C55906 Blurred vision Blurred vision A disorder characterized by visual perception of unclear or fuzzy images. NCI A disorder characterized by visual perception of unclear or fuzzy images. CTCAE_v5 Blurred Vision, CTCAE PT NCI Blurred vision PT CTCAE_v5 ctcae5:C55907 Intervention not indicated Intervention not indicated Grade 1 Blurred Vision, CTCAE Grade 1 Blurred vision 10005886 C55907 Grade 1 Blurred vision Grade 1 Blurred vision Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 1 Blurred Vision, CTCAE PT NCI Grade 1 Blurred vision PT CTCAE_v5 ctcae5:C55908 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Grade 2 Blurred Vision, CTCAE Grade 2 Blurred vision 10005886 C55908 Grade 2 Blurred vision Grade 2 Blurred vision Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL CTCAE_v5 Grade 2 Blurred Vision, CTCAE PT NCI Grade 2 Blurred vision PT CTCAE_v5 ctcae5:C55909 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL Grade 3 Blurred Vision, CTCAE Grade 3 Blurred vision 10005886 C55909 Grade 3 Blurred vision Grade 3 Blurred vision Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL CTCAE_v5 Grade 3 Blurred Vision, CTCAE PT NCI Grade 3 Blurred vision PT CTCAE_v5 ctcae5:C55910 Best corrected visual acuity of 20/200 or worse in the affected eye Best corrected visual acuity of 20/200 or worse in the affected eye Grade 4 Blurred Vision, CTCAE Grade 4 Blurred vision 10005886 C55910 Grade 4 Blurred vision Grade 4 Blurred vision Best corrected visual acuity of 20/200 or worse in the affected eye NCI Best corrected visual acuity of 20/200 or worse in the affected eye CTCAE_v5 Grade 4 Blurred Vision, CTCAE PT NCI Grade 4 Blurred vision PT CTCAE_v5 ctcae5:C55917 Symptomatic but not limiting ADL Symptomatic but not limiting ADL Grade 1 Photophobia Grade 1 Photophobia, CTCAE 10034960 C55917 Grade 1 Photophobia Grade 1 Photophobia Symptomatic but not limiting ADL NCI Symptomatic but not limiting ADL CTCAE_v5 Grade 1 Photophobia PT CTCAE_v5 Grade 1 Photophobia, CTCAE PT NCI ctcae5:C55918 Limiting instrumental ADL Limiting instrumental ADL Grade 2 Photophobia Grade 2 Photophobia, CTCAE 10034960 C55918 Grade 2 Photophobia Grade 2 Photophobia Limiting instrumental ADL NCI Limiting instrumental ADL CTCAE_v5 Grade 2 Photophobia PT CTCAE_v5 Grade 2 Photophobia, CTCAE PT NCI ctcae5:C55919 Limiting self care ADL Limiting self care ADL Grade 3 Photophobia Grade 3 Photophobia, CTCAE 10034960 C55919 Grade 3 Photophobia Grade 3 Photophobia Limiting self care ADL NCI Limiting self care ADL CTCAE_v5 Grade 3 Photophobia PT CTCAE_v5 Grade 3 Photophobia, CTCAE PT NCI ctcae5:C55922 Intervention not indicated Intervention not indicated Grade 1 Vitreous Hemorrhage, CTCAE Grade 1 Vitreous hemorrhage 10047656 C55922 Grade 1 Vitreous hemorrhage Grade 1 Vitreous hemorrhage Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 1 Vitreous Hemorrhage, CTCAE PT NCI Grade 1 Vitreous hemorrhage PT CTCAE_v5 ctcae5:C55923 Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL Grade 2 Vitreous Hemorrhage, CTCAE Grade 2 Vitreous hemorrhage 10047656 C55923 Grade 2 Vitreous hemorrhage Grade 2 Vitreous hemorrhage Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL NCI Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); limiting instrumental ADL CTCAE_v5 Grade 2 Vitreous Hemorrhage, CTCAE PT NCI Grade 2 Vitreous hemorrhage PT CTCAE_v5 ctcae5:C55924 Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL; vitrectomy indicated Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL; vitrectomy indicated Grade 3 Vitreous Hemorrhage, CTCAE Grade 3 Vitreous hemorrhage 10047656 C55924 Grade 3 Vitreous hemorrhage Grade 3 Vitreous hemorrhage Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL; vitrectomy indicated NCI Symptomatic with marked decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200); limiting self care ADL; vitrectomy indicated CTCAE_v5 Grade 3 Vitreous Hemorrhage, CTCAE PT NCI Grade 3 Vitreous hemorrhage PT CTCAE_v5 ctcae5:C55937 Laboratory evidence of hemolysis only (e.g., direct antiglobulin test; DAT; Coombs'; schistocytes; decreased haptoglobin) Laboratory evidence of hemolysis only (e.g., direct antiglobulin test; DAT; Coombs'; schistocytes; decreased haptoglobin) Grade 1 Hemolysis Grade 1 Hemolysis, CTCAE 10019491 C55937 Grade 1 Hemolysis Grade 1 Hemolysis Laboratory evidence of hemolysis only (e.g., direct antiglobulin test; DAT; Coombs'; schistocytes; decreased haptoglobin) NCI Laboratory evidence of hemolysis only (e.g., direct antiglobulin test; DAT; Coombs'; schistocytes; decreased haptoglobin) CTCAE_v5 Grade 1 Hemolysis PT CTCAE_v5 Grade 1 Hemolysis, CTCAE PT NCI ctcae5:C55947 Evidence of hemolysis and >=2 g decrease in hemoglobin Evidence of hemolysis and >=2 g decrease in hemoglobin Grade 2 Hemolysis Grade 2 Hemolysis, CTCAE 10019491 C55947 Grade 2 Hemolysis Grade 2 Hemolysis Evidence of hemolysis and >=2 g decrease in hemoglobin NCI Evidence of hemolysis and >=2 g decrease in hemoglobin CTCAE_v5 Grade 2 Hemolysis PT CTCAE_v5 Grade 2 Hemolysis, CTCAE PT NCI ctcae5:C55948 Moderate symptoms; intervention not indicated Moderate symptoms; intervention not indicated Grade 2 Iron Overload, CTCAE Grade 2 Iron overload 10065973 C55948 Grade 2 Iron overload Grade 2 Iron overload Moderate symptoms; intervention not indicated NCI Moderate symptoms; intervention not indicated CTCAE_v5 Grade 2 Iron Overload, CTCAE PT NCI Grade 2 Iron overload PT CTCAE_v5 ctcae5:C55959 Transfusion or medical intervention indicated (e.g., steroids) Transfusion or medical intervention indicated (e.g., steroids) Grade 3 Hemolysis Grade 3 Hemolysis, CTCAE 10019491 C55959 Grade 3 Hemolysis Grade 3 Hemolysis Transfusion or medical intervention indicated (e.g., steroids) NCI Transfusion or medical intervention indicated (e.g., steroids) CTCAE_v5 Grade 3 Hemolysis PT CTCAE_v5 Grade 3 Hemolysis, CTCAE PT NCI ctcae5:C55960 Severe symptoms; intervention indicated Severe symptoms; intervention indicated Grade 3 Iron Overload, CTCAE Grade 3 Iron overload 10065973 C55960 Grade 3 Iron overload Grade 3 Iron overload Severe symptoms; intervention indicated NCI Severe symptoms; intervention indicated CTCAE_v5 Grade 3 Iron Overload, CTCAE PT NCI Grade 3 Iron overload PT CTCAE_v5 ctcae5:C55969 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hemolysis Grade 4 Hemolysis, CTCAE 10019491 C55969 Grade 4 Hemolysis Grade 4 Hemolysis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hemolysis PT CTCAE_v5 Grade 4 Hemolysis, CTCAE PT NCI ctcae5:C55970 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Iron Overload, CTCAE Grade 4 Iron overload 10065973 C55970 Grade 4 Iron overload Grade 4 Iron overload Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Iron Overload, CTCAE PT NCI Grade 4 Iron overload PT CTCAE_v5 ctcae5:C55982 Death Death Grade 5 Hemolysis Grade 5 Hemolysis, CTCAE 10019491 C55982 Grade 5 Hemolysis Grade 5 Hemolysis Death NCI Death CTCAE_v5 Grade 5 Hemolysis PT CTCAE_v5 Grade 5 Hemolysis, CTCAE PT NCI ctcae5:C55983 Death Death Grade 5 Iron Overload, CTCAE Grade 5 Iron overload 10065973 C55983 Grade 5 Iron overload Grade 5 Iron overload Death NCI Death CTCAE_v5 Grade 5 Iron Overload, CTCAE PT NCI Grade 5 Iron overload PT CTCAE_v5 ctcae5:C55992 A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. Hemolysis Hemolysis, CTCAE 10019491 C55992 Hemolysis Hemolysis A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. NCI A disorder characterized by laboratory test results that indicate widespread erythrocyte cell membrane destruction. CTCAE_v5 Hemolysis PT CTCAE_v5 Hemolysis, CTCAE PT NCI ctcae5:C55993 A disorder characterized by accumulation of iron in the tissues. A disorder characterized by accumulation of iron in the tissues. Iron Overload, CTCAE Iron overload 10065973 C55993 Iron overload Iron overload A disorder characterized by accumulation of iron in the tissues. NCI A disorder characterized by accumulation of iron in the tissues. CTCAE_v5 Iron Overload, CTCAE PT NCI Iron overload PT CTCAE_v5 ctcae5:C56011 Mild pain Mild pain Grade 1 Back Pain, CTCAE Grade 1 Back pain 10003988 C56011 Grade 1 Back pain Grade 1 Back pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Back Pain, CTCAE PT NCI Grade 1 Back pain PT CTCAE_v5 ctcae5:C56012 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Back Pain, CTCAE Grade 2 Back pain 10003988 C56012 Grade 2 Back pain Grade 2 Back pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Back Pain, CTCAE PT NCI Grade 2 Back pain PT CTCAE_v5 ctcae5:C56013 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Back Pain, CTCAE Grade 3 Back pain 10003988 C56013 Grade 3 Back pain Grade 3 Back pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Back Pain, CTCAE PT NCI Grade 3 Back pain PT CTCAE_v5 ctcae5:C56021 Mild pain Mild pain Grade 1 Bone Pain, CTCAE Grade 1 Bone pain 10006002 C56021 Grade 1 Bone pain Grade 1 Bone pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Bone Pain, CTCAE PT NCI Grade 1 Bone pain PT CTCAE_v5 ctcae5:C56022 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Bone Pain, CTCAE Grade 2 Bone pain 10006002 C56022 Grade 2 Bone pain Grade 2 Bone pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Bone Pain, CTCAE PT NCI Grade 2 Bone pain PT CTCAE_v5 ctcae5:C56023 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Bone Pain, CTCAE Grade 3 Bone pain 10006002 C56023 Grade 3 Bone pain Grade 3 Bone pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Bone Pain, CTCAE PT NCI Grade 3 Bone pain PT CTCAE_v5 ctcae5:C56026 Mild pain Mild pain Grade 1 Breast Pain, CTCAE Grade 1 Breast pain 10006298 C56026 Grade 1 Breast pain Grade 1 Breast pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Breast Pain, CTCAE PT NCI Grade 1 Breast pain PT CTCAE_v5 ctcae5:C56027 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Breast Pain, CTCAE Grade 2 Breast pain 10006298 C56027 Grade 2 Breast pain Grade 2 Breast pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Breast Pain, CTCAE PT NCI Grade 2 Breast pain PT CTCAE_v5 ctcae5:C56028 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Breast Pain, CTCAE Grade 3 Breast pain 10006298 C56028 Grade 3 Breast pain Grade 3 Breast pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Breast Pain, CTCAE PT NCI Grade 3 Breast pain PT CTCAE_v5 ctcae5:C56031 Mild pain Mild pain Grade 1 Buttock Pain, CTCAE Grade 1 Buttock pain 10048677 C56031 Grade 1 Buttock pain Grade 1 Buttock pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Buttock Pain, CTCAE PT NCI Grade 1 Buttock pain PT CTCAE_v5 ctcae5:C56032 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Buttock Pain, CTCAE Grade 2 Buttock pain 10048677 C56032 Grade 2 Buttock pain Grade 2 Buttock pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Buttock Pain, CTCAE PT NCI Grade 2 Buttock pain PT CTCAE_v5 ctcae5:C56033 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Buttock Pain, CTCAE Grade 3 Buttock pain 10048677 C56033 Grade 3 Buttock pain Grade 3 Buttock pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Buttock Pain, CTCAE PT NCI Grade 3 Buttock pain PT CTCAE_v5 ctcae5:C56041 Mild pain Mild pain Grade 1 Chest Wall Pain, CTCAE Grade 1 Chest wall pain 10008496 C56041 Grade 1 Chest wall pain Grade 1 Chest wall pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Chest Wall Pain, CTCAE PT NCI Grade 1 Chest wall pain PT CTCAE_v5 ctcae5:C56042 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Chest Wall Pain, CTCAE Grade 2 Chest wall pain 10008496 C56042 Grade 2 Chest wall pain Grade 2 Chest wall pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Chest Wall Pain, CTCAE PT NCI Grade 2 Chest wall pain PT CTCAE_v5 ctcae5:C56043 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Chest Wall Pain, CTCAE Grade 3 Chest wall pain 10008496 C56043 Grade 3 Chest wall pain Grade 3 Chest wall pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Chest Wall Pain, CTCAE PT NCI Grade 3 Chest wall pain PT CTCAE_v5 ctcae5:C56061 Mild pain Mild pain Grade 1 External Ear Pain, CTCAE Grade 1 External ear pain 10065785 C56061 Grade 1 External ear pain Grade 1 External ear pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 External Ear Pain, CTCAE PT NCI Grade 1 External ear pain PT CTCAE_v5 ctcae5:C56062 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 External Ear Pain, CTCAE Grade 2 External ear pain 10065785 C56062 Grade 2 External ear pain Grade 2 External ear pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 External Ear Pain, CTCAE PT NCI Grade 2 External ear pain PT CTCAE_v5 ctcae5:C56063 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 External Ear Pain, CTCAE Grade 3 External ear pain 10065785 C56063 Grade 3 External ear pain Grade 3 External ear pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 External Ear Pain, CTCAE PT NCI Grade 3 External ear pain PT CTCAE_v5 ctcae5:C56071 Mild pain Mild pain Grade 1 Eye Pain, CTCAE Grade 1 Eye pain 10015958 C56071 Grade 1 Eye pain Grade 1 Eye pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Eye Pain, CTCAE PT NCI Grade 1 Eye pain PT CTCAE_v5 ctcae5:C56072 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Eye Pain, CTCAE Grade 2 Eye pain 10015958 C56072 Grade 2 Eye pain Grade 2 Eye pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Eye Pain, CTCAE PT NCI Grade 2 Eye pain PT CTCAE_v5 ctcae5:C56073 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Eye Pain, CTCAE Grade 3 Eye pain 10015958 C56073 Grade 3 Eye pain Grade 3 Eye pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Eye Pain, CTCAE PT NCI Grade 3 Eye pain PT CTCAE_v5 ctcae5:C56081 Mild pain Mild pain Grade 1 Gallbladder Pain, CTCAE Grade 1 Gallbladder pain 10017638 C56081 Grade 1 Gallbladder pain Grade 1 Gallbladder pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Gallbladder Pain, CTCAE PT NCI Grade 1 Gallbladder pain PT CTCAE_v5 ctcae5:C56082 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Gallbladder Pain, CTCAE Grade 2 Gallbladder pain 10017638 C56082 Grade 2 Gallbladder pain Grade 2 Gallbladder pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Gallbladder Pain, CTCAE PT NCI Grade 2 Gallbladder pain PT CTCAE_v5 ctcae5:C56083 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Gallbladder Pain, CTCAE Grade 3 Gallbladder pain 10017638 C56083 Grade 3 Gallbladder pain Grade 3 Gallbladder pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Gallbladder Pain, CTCAE PT NCI Grade 3 Gallbladder pain PT CTCAE_v5 ctcae5:C56111 Mild pain Mild pain Grade 1 Lip Pain, CTCAE Grade 1 Lip pain 10024561 C56111 Grade 1 Lip pain Grade 1 Lip pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Lip Pain, CTCAE PT NCI Grade 1 Lip pain PT CTCAE_v5 ctcae5:C56112 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Lip Pain, CTCAE Grade 2 Lip pain 10024561 C56112 Grade 2 Lip pain Grade 2 Lip pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Lip Pain, CTCAE PT NCI Grade 2 Lip pain PT CTCAE_v5 ctcae5:C56113 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Lip Pain, CTCAE Grade 3 Lip pain 10024561 C56113 Grade 3 Lip pain Grade 3 Lip pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Lip Pain, CTCAE PT NCI Grade 3 Lip pain PT CTCAE_v5 ctcae5:C56121 Mild pain Mild pain Grade 1 Lymph Node Pain, CTCAE Grade 1 Lymph node pain 10025182 C56121 Grade 1 Lymph node pain Grade 1 Lymph node pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Lymph Node Pain, CTCAE PT NCI Grade 1 Lymph node pain PT CTCAE_v5 ctcae5:C56122 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Lymph Node Pain, CTCAE Grade 2 Lymph node pain 10025182 C56122 Grade 2 Lymph node pain Grade 2 Lymph node pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Lymph Node Pain, CTCAE PT NCI Grade 2 Lymph node pain PT CTCAE_v5 ctcae5:C56123 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Lymph Node Pain, CTCAE Grade 3 Lymph node pain 10025182 C56123 Grade 3 Lymph node pain Grade 3 Lymph node pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Lymph Node Pain, CTCAE PT NCI Grade 3 Lymph node pain PT CTCAE_v5 ctcae5:C56136 Mild pain Mild pain Grade 1 Neck Pain, CTCAE Grade 1 Neck pain 10028836 C56136 Grade 1 Neck pain Grade 1 Neck pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Neck Pain, CTCAE PT NCI Grade 1 Neck pain PT CTCAE_v5 ctcae5:C56137 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Neck Pain, CTCAE Grade 2 Neck pain 10028836 C56137 Grade 2 Neck pain Grade 2 Neck pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Neck Pain, CTCAE PT NCI Grade 2 Neck pain PT CTCAE_v5 ctcae5:C56138 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Neck Pain, CTCAE Grade 3 Neck pain 10028836 C56138 Grade 3 Neck pain Grade 3 Neck pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Neck Pain, CTCAE PT NCI Grade 3 Neck pain PT CTCAE_v5 ctcae5:C56146 Mild pain Mild pain Grade 1 Oral Pain, CTCAE Grade 1 Oral pain 10031009 C56146 Grade 1 Oral pain Grade 1 Oral pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Oral Pain, CTCAE PT NCI Grade 1 Oral pain PT CTCAE_v5 ctcae5:C56147 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Oral Pain, CTCAE Grade 2 Oral pain 10031009 C56147 Grade 2 Oral pain Grade 2 Oral pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Oral Pain, CTCAE PT NCI Grade 2 Oral pain PT CTCAE_v5 ctcae5:C56148 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Oral Pain, CTCAE Grade 3 Oral pain 10031009 C56148 Grade 3 Oral pain Grade 3 Oral pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Oral Pain, CTCAE PT NCI Grade 3 Oral pain PT CTCAE_v5 ctcae5:C56157 Present Present Grade 2 Ovulation Pain, CTCAE Grade 2 Ovulation pain 10033314 C56157 Grade 2 Ovulation pain Grade 2 Ovulation pain Present NCI Present CTCAE_v5 Grade 2 Ovulation Pain, CTCAE PT NCI Grade 2 Ovulation pain PT CTCAE_v5 ctcae5:C56171 Mild pain Mild pain Grade 1 Penile Pain, CTCAE Grade 1 Penile pain 10034310 C56171 Grade 1 Penile pain Grade 1 Penile pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Penile Pain, CTCAE PT NCI Grade 1 Penile pain PT CTCAE_v5 ctcae5:C56172 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Penile Pain, CTCAE Grade 2 Penile pain 10034310 C56172 Grade 2 Penile pain Grade 2 Penile pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Penile Pain, CTCAE PT NCI Grade 2 Penile pain PT CTCAE_v5 ctcae5:C56173 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Penile Pain, CTCAE Grade 3 Penile pain 10034310 C56173 Grade 3 Penile pain Grade 3 Penile pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Penile Pain, CTCAE PT NCI Grade 3 Penile pain PT CTCAE_v5 ctcae5:C56211 Mild pain Mild pain Grade 1 Scalp Pain, CTCAE Grade 1 Scalp pain 10049120 C56211 Grade 1 Scalp pain Grade 1 Scalp pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Scalp Pain, CTCAE PT NCI Grade 1 Scalp pain PT CTCAE_v5 ctcae5:C56212 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Scalp Pain, CTCAE Grade 2 Scalp pain 10049120 C56212 Grade 2 Scalp pain Grade 2 Scalp pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Scalp Pain, CTCAE PT NCI Grade 2 Scalp pain PT CTCAE_v5 ctcae5:C56213 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Scalp Pain, CTCAE Grade 3 Scalp pain 10049120 C56213 Grade 3 Scalp pain Grade 3 Scalp pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Scalp Pain, CTCAE PT NCI Grade 3 Scalp pain PT CTCAE_v5 ctcae5:C56221 Mild pain Mild pain Grade 1 Sinus Pain, CTCAE Grade 1 Sinus pain 10040747 C56221 Grade 1 Sinus pain Grade 1 Sinus pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Sinus Pain, CTCAE PT NCI Grade 1 Sinus pain PT CTCAE_v5 ctcae5:C56222 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Sinus Pain, CTCAE Grade 2 Sinus pain 10040747 C56222 Grade 2 Sinus pain Grade 2 Sinus pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Sinus Pain, CTCAE PT NCI Grade 2 Sinus pain PT CTCAE_v5 ctcae5:C56223 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Sinus Pain, CTCAE Grade 3 Sinus pain 10040747 C56223 Grade 3 Sinus pain Grade 3 Sinus pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Sinus Pain, CTCAE PT NCI Grade 3 Sinus pain PT CTCAE_v5 ctcae5:C56231 Mild pain Mild pain Grade 1 Stomach Pain, CTCAE Grade 1 Stomach pain 10042112 C56231 Grade 1 Stomach pain Grade 1 Stomach pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Stomach Pain, CTCAE PT NCI Grade 1 Stomach pain PT CTCAE_v5 ctcae5:C56232 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Stomach Pain, CTCAE Grade 2 Stomach pain 10042112 C56232 Grade 2 Stomach pain Grade 2 Stomach pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Stomach Pain, CTCAE PT NCI Grade 2 Stomach pain PT CTCAE_v5 ctcae5:C56233 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Stomach Pain, CTCAE Grade 3 Stomach pain 10042112 C56233 Grade 3 Stomach pain Grade 3 Stomach pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Stomach Pain, CTCAE PT NCI Grade 3 Stomach pain PT CTCAE_v5 ctcae5:C56246 Mild pain Mild pain Grade 1 Tumor Pain, CTCAE Grade 1 Tumor pain 10045158 C56246 Grade 1 Tumor pain Grade 1 Tumor pain Mild pain NCI Mild pain CTCAE_v5 Grade 1 Tumor Pain, CTCAE PT NCI Grade 1 Tumor pain PT CTCAE_v5 ctcae5:C56247 Moderate pain; limiting instrumental ADL Moderate pain; limiting instrumental ADL Grade 2 Tumor Pain, CTCAE Grade 2 Tumor pain 10045158 C56247 Grade 2 Tumor pain Grade 2 Tumor pain Moderate pain; limiting instrumental ADL NCI Moderate pain; limiting instrumental ADL CTCAE_v5 Grade 2 Tumor Pain, CTCAE PT NCI Grade 2 Tumor pain PT CTCAE_v5 ctcae5:C56248 Severe pain; limiting self care ADL Severe pain; limiting self care ADL Grade 3 Tumor Pain, CTCAE Grade 3 Tumor pain 10045158 C56248 Grade 3 Tumor pain Grade 3 Tumor pain Severe pain; limiting self care ADL NCI Severe pain; limiting self care ADL CTCAE_v5 Grade 3 Tumor Pain, CTCAE PT NCI Grade 3 Tumor pain PT CTCAE_v5 ctcae5:C56298 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Hematoma Grade 1 Hematoma, CTCAE 10019428 C56298 Grade 1 Hematoma Grade 1 Hematoma Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Hematoma PT CTCAE_v5 Grade 1 Hematoma, CTCAE PT NCI ctcae5:C56299 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Ileal Hemorrhage, CTCAE Grade 1 Ileal hemorrhage 10055287 C56299 Grade 1 Ileal hemorrhage Grade 1 Ileal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Ileal Hemorrhage, CTCAE PT NCI Grade 1 Ileal hemorrhage PT CTCAE_v5 ctcae5:C56300 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Jejunal Hemorrhage, CTCAE Grade 1 Jejunal hemorrhage 10055300 C56300 Grade 1 Jejunal hemorrhage Grade 1 Jejunal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Jejunal Hemorrhage, CTCAE PT NCI Grade 1 Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56301 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Renal Hemorrhage, CTCAE Grade 1 Renal hemorrhage 10038463 C56301 Grade 1 Renal hemorrhage Grade 1 Renal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Renal Hemorrhage, CTCAE PT NCI Grade 1 Renal hemorrhage PT CTCAE_v5 ctcae5:C56302 Mild cough or trace hemoptysis; laryngoscopic findings Mild cough or trace hemoptysis; laryngoscopic findings Grade 1 Laryngeal Hemorrhage, CTCAE Grade 1 Laryngeal hemorrhage 10065759 C56302 Grade 1 Laryngeal hemorrhage Grade 1 Laryngeal hemorrhage Mild cough or trace hemoptysis; laryngoscopic findings NCI Mild cough or trace hemoptysis; laryngoscopic findings CTCAE_v5 Grade 1 Laryngeal Hemorrhage, CTCAE PT NCI Grade 1 Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56306 Mild symptoms; intervention not indicated; radiologic evidence only Mild symptoms; intervention not indicated; radiologic evidence only Grade 1 Mediastinal Hemorrhage, CTCAE Grade 1 Mediastinal hemorrhage 10056356 C56306 Grade 1 Mediastinal hemorrhage Grade 1 Mediastinal hemorrhage Mild symptoms; intervention not indicated; radiologic evidence only NCI Mild symptoms; intervention not indicated; radiologic evidence only CTCAE_v5 Grade 1 Mediastinal Hemorrhage, CTCAE PT NCI Grade 1 Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56308 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Oral Hemorrhage, CTCAE Grade 1 Oral hemorrhage 10030980 C56308 Grade 1 Oral hemorrhage Grade 1 Oral hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Oral Hemorrhage, CTCAE PT NCI Grade 1 Oral hemorrhage PT CTCAE_v5 ctcae5:C56309 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Ovarian Hemorrhage, CTCAE Grade 1 Ovarian hemorrhage 10065763 C56309 Grade 1 Ovarian hemorrhage Grade 1 Ovarian hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Ovarian Hemorrhage, CTCAE PT NCI Grade 1 Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56310 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Pancreatic Hemorrhage, CTCAE Grade 1 Pancreatic hemorrhage 10033626 C56310 Grade 1 Pancreatic hemorrhage Grade 1 Pancreatic hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Pancreatic Hemorrhage, CTCAE PT NCI Grade 1 Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56313 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Pharyngeal Hemorrhage, CTCAE Grade 1 Pharyngeal hemorrhage 10055315 C56313 Grade 1 Pharyngeal hemorrhage Grade 1 Pharyngeal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Pharyngeal Hemorrhage, CTCAE PT NCI Grade 1 Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56314 Asymptomatic; mild hemorrhage confirmed by thoracentesis Asymptomatic; mild hemorrhage confirmed by thoracentesis Grade 1 Pleural Hemorrhage, CTCAE Grade 1 Pleural hemorrhage 10055319 C56314 Grade 1 Pleural hemorrhage Grade 1 Pleural hemorrhage Asymptomatic; mild hemorrhage confirmed by thoracentesis NCI Asymptomatic; mild hemorrhage confirmed by thoracentesis CTCAE_v5 Grade 1 Pleural Hemorrhage, CTCAE PT NCI Grade 1 Pleural hemorrhage PT CTCAE_v5 ctcae5:C56315 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Prostatic Hemorrhage, CTCAE Grade 1 Prostatic hemorrhage 10055325 C56315 Grade 1 Prostatic hemorrhage Grade 1 Prostatic hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Prostatic Hemorrhage, CTCAE PT NCI Grade 1 Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56317 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Rectal Hemorrhage, CTCAE Grade 1 Rectal hemorrhage 10038064 C56317 Grade 1 Rectal hemorrhage Grade 1 Rectal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Rectal Hemorrhage, CTCAE PT NCI Grade 1 Rectal hemorrhage PT CTCAE_v5 ctcae5:C56320 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Spermatic Cord Hemorrhage, CTCAE Grade 1 Spermatic cord hemorrhage 10065762 C56320 Grade 1 Spermatic cord hemorrhage Grade 1 Spermatic cord hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Spermatic Cord Hemorrhage, CTCAE PT NCI Grade 1 Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56323 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Testicular Hemorrhage, CTCAE Grade 1 Testicular hemorrhage 10055347 C56323 Grade 1 Testicular hemorrhage Grade 1 Testicular hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Testicular Hemorrhage, CTCAE PT NCI Grade 1 Testicular hemorrhage PT CTCAE_v5 ctcae5:C56324 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Tracheal Hemorrhage, CTCAE Grade 1 Tracheal hemorrhage 10062548 C56324 Grade 1 Tracheal hemorrhage Grade 1 Tracheal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Tracheal Hemorrhage, CTCAE PT NCI Grade 1 Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56329 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Uterine Hemorrhage, CTCAE Grade 1 Uterine hemorrhage 10046789 C56329 Grade 1 Uterine hemorrhage Grade 1 Uterine hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Uterine Hemorrhage, CTCAE PT NCI Grade 1 Uterine hemorrhage PT CTCAE_v5 ctcae5:C56330 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Vaginal Hemorrhage, CTCAE Grade 1 Vaginal hemorrhage 10046912 C56330 Grade 1 Vaginal hemorrhage Grade 1 Vaginal hemorrhage Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Vaginal Hemorrhage, CTCAE PT NCI Grade 1 Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56342 Self-limited; intervention not indicated Self-limited; intervention not indicated Grade 2 Esophageal Varices Hemorrhage, CTCAE Grade 2 Esophageal varices hemorrhage 10015453 C56342 Grade 2 Esophageal varices hemorrhage Grade 2 Esophageal varices hemorrhage Self-limited; intervention not indicated NCI Self-limited; intervention not indicated CTCAE_v5 Grade 2 Esophageal Varices Hemorrhage, CTCAE PT NCI Grade 2 Esophageal varices hemorrhage PT CTCAE_v5 ctcae5:C56347 Minimally invasive evacuation or aspiration indicated Minimally invasive evacuation or aspiration indicated Grade 2 Hematoma Grade 2 Hematoma, CTCAE 10019428 C56347 Grade 2 Hematoma Grade 2 Hematoma Minimally invasive evacuation or aspiration indicated NCI Minimally invasive evacuation or aspiration indicated CTCAE_v5 Grade 2 Hematoma PT CTCAE_v5 Grade 2 Hematoma, CTCAE PT NCI ctcae5:C56348 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Ileal Hemorrhage, CTCAE Grade 2 Ileal hemorrhage 10055287 C56348 Grade 2 Ileal hemorrhage Grade 2 Ileal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Ileal Hemorrhage, CTCAE PT NCI Grade 2 Ileal hemorrhage PT CTCAE_v5 ctcae5:C56349 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Jejunal Hemorrhage, CTCAE Grade 2 Jejunal hemorrhage 10055300 C56349 Grade 2 Jejunal hemorrhage Grade 2 Jejunal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Jejunal Hemorrhage, CTCAE PT NCI Grade 2 Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56350 Analgesics and hematocrit monitoring indicated Analgesics and hematocrit monitoring indicated Grade 2 Renal Hemorrhage, CTCAE Grade 2 Renal hemorrhage 10038463 C56350 Grade 2 Renal hemorrhage Grade 2 Renal hemorrhage Analgesics and hematocrit monitoring indicated NCI Analgesics and hematocrit monitoring indicated CTCAE_v5 Grade 2 Renal Hemorrhage, CTCAE PT NCI Grade 2 Renal hemorrhage PT CTCAE_v5 ctcae5:C56351 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Laryngeal Hemorrhage, CTCAE Grade 2 Laryngeal hemorrhage 10065759 C56351 Grade 2 Laryngeal hemorrhage Grade 2 Laryngeal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Laryngeal Hemorrhage, CTCAE PT NCI Grade 2 Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56355 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Mediastinal Hemorrhage, CTCAE Grade 2 Mediastinal hemorrhage 10056356 C56355 Grade 2 Mediastinal hemorrhage Grade 2 Mediastinal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Mediastinal Hemorrhage, CTCAE PT NCI Grade 2 Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56357 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Oral Hemorrhage, CTCAE Grade 2 Oral hemorrhage 10030980 C56357 Grade 2 Oral hemorrhage Grade 2 Oral hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Oral Hemorrhage, CTCAE PT NCI Grade 2 Oral hemorrhage PT CTCAE_v5 ctcae5:C56358 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Ovarian Hemorrhage, CTCAE Grade 2 Ovarian hemorrhage 10065763 C56358 Grade 2 Ovarian hemorrhage Grade 2 Ovarian hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Ovarian Hemorrhage, CTCAE PT NCI Grade 2 Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56359 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Pancreatic Hemorrhage, CTCAE Grade 2 Pancreatic hemorrhage 10033626 C56359 Grade 2 Pancreatic hemorrhage Grade 2 Pancreatic hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Pancreatic Hemorrhage, CTCAE PT NCI Grade 2 Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56362 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Pharyngeal Hemorrhage, CTCAE Grade 2 Pharyngeal hemorrhage 10055315 C56362 Grade 2 Pharyngeal hemorrhage Grade 2 Pharyngeal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Pharyngeal Hemorrhage, CTCAE PT NCI Grade 2 Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56363 Symptomatic or associated with pneumothorax; chest tube drainage indicated Symptomatic or associated with pneumothorax; chest tube drainage indicated Grade 2 Pleural Hemorrhage, CTCAE Grade 2 Pleural hemorrhage 10055319 C56363 Grade 2 Pleural hemorrhage Grade 2 Pleural hemorrhage Symptomatic or associated with pneumothorax; chest tube drainage indicated NCI Symptomatic or associated with pneumothorax; chest tube drainage indicated CTCAE_v5 Grade 2 Pleural Hemorrhage, CTCAE PT NCI Grade 2 Pleural hemorrhage PT CTCAE_v5 ctcae5:C56364 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Prostatic Hemorrhage, CTCAE Grade 2 Prostatic hemorrhage 10055325 C56364 Grade 2 Prostatic hemorrhage Grade 2 Prostatic hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Prostatic Hemorrhage, CTCAE PT NCI Grade 2 Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56366 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Rectal Hemorrhage, CTCAE Grade 2 Rectal hemorrhage 10038064 C56366 Grade 2 Rectal hemorrhage Grade 2 Rectal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Rectal Hemorrhage, CTCAE PT NCI Grade 2 Rectal hemorrhage PT CTCAE_v5 ctcae5:C56369 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Spermatic Cord Hemorrhage, CTCAE Grade 2 Spermatic cord hemorrhage 10065762 C56369 Grade 2 Spermatic cord hemorrhage Grade 2 Spermatic cord hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Spermatic Cord Hemorrhage, CTCAE PT NCI Grade 2 Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56372 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Testicular Hemorrhage, CTCAE Grade 2 Testicular hemorrhage 10055347 C56372 Grade 2 Testicular hemorrhage Grade 2 Testicular hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Testicular Hemorrhage, CTCAE PT NCI Grade 2 Testicular hemorrhage PT CTCAE_v5 ctcae5:C56373 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Tracheal Hemorrhage, CTCAE Grade 2 Tracheal hemorrhage 10062548 C56373 Grade 2 Tracheal hemorrhage Grade 2 Tracheal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Tracheal Hemorrhage, CTCAE PT NCI Grade 2 Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56378 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Uterine Hemorrhage, CTCAE Grade 2 Uterine hemorrhage 10046789 C56378 Grade 2 Uterine hemorrhage Grade 2 Uterine hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Uterine Hemorrhage, CTCAE PT NCI Grade 2 Uterine hemorrhage PT CTCAE_v5 ctcae5:C56379 Moderate symptoms; intervention indicated Moderate symptoms; intervention indicated Grade 2 Vaginal Hemorrhage, CTCAE Grade 2 Vaginal hemorrhage 10046912 C56379 Grade 2 Vaginal hemorrhage Grade 2 Vaginal hemorrhage Moderate symptoms; intervention indicated NCI Moderate symptoms; intervention indicated CTCAE_v5 Grade 2 Vaginal Hemorrhage, CTCAE PT NCI Grade 2 Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56391 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Esophageal Varices Hemorrhage, CTCAE Grade 3 Esophageal varices hemorrhage 10015453 C56391 Grade 3 Esophageal varices hemorrhage Grade 3 Esophageal varices hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Esophageal Varices Hemorrhage, CTCAE PT NCI Grade 3 Esophageal varices hemorrhage PT CTCAE_v5 ctcae5:C56396 Transfusion; invasive intervention indicated Transfusion; invasive intervention indicated Grade 3 Hematoma Grade 3 Hematoma, CTCAE 10019428 C56396 Grade 3 Hematoma Grade 3 Hematoma Transfusion; invasive intervention indicated NCI Transfusion; invasive intervention indicated CTCAE_v5 Grade 3 Hematoma PT CTCAE_v5 Grade 3 Hematoma, CTCAE PT NCI ctcae5:C56398 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Ileal Hemorrhage, CTCAE Grade 3 Ileal hemorrhage 10055287 C56398 Grade 3 Ileal hemorrhage Grade 3 Ileal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Ileal Hemorrhage, CTCAE PT NCI Grade 3 Ileal hemorrhage PT CTCAE_v5 ctcae5:C56399 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Jejunal Hemorrhage, CTCAE Grade 3 Jejunal hemorrhage 10055300 C56399 Grade 3 Jejunal hemorrhage Grade 3 Jejunal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Jejunal Hemorrhage, CTCAE PT NCI Grade 3 Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56400 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Renal Hemorrhage, CTCAE Grade 3 Renal hemorrhage 10038463 C56400 Grade 3 Renal hemorrhage Grade 3 Renal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Renal Hemorrhage, CTCAE PT NCI Grade 3 Renal hemorrhage PT CTCAE_v5 ctcae5:C56401 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Laryngeal Hemorrhage, CTCAE Grade 3 Laryngeal hemorrhage 10065759 C56401 Grade 3 Laryngeal hemorrhage Grade 3 Laryngeal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Laryngeal Hemorrhage, CTCAE PT NCI Grade 3 Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56405 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Mediastinal Hemorrhage, CTCAE Grade 3 Mediastinal hemorrhage 10056356 C56405 Grade 3 Mediastinal hemorrhage Grade 3 Mediastinal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Mediastinal Hemorrhage, CTCAE PT NCI Grade 3 Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56407 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Oral Hemorrhage, CTCAE Grade 3 Oral hemorrhage 10030980 C56407 Grade 3 Oral hemorrhage Grade 3 Oral hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Oral Hemorrhage, CTCAE PT NCI Grade 3 Oral hemorrhage PT CTCAE_v5 ctcae5:C56408 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Ovarian Hemorrhage, CTCAE Grade 3 Ovarian hemorrhage 10065763 C56408 Grade 3 Ovarian hemorrhage Grade 3 Ovarian hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Ovarian Hemorrhage, CTCAE PT NCI Grade 3 Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56409 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Pancreatic Hemorrhage, CTCAE Grade 3 Pancreatic hemorrhage 10033626 C56409 Grade 3 Pancreatic hemorrhage Grade 3 Pancreatic hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Pancreatic Hemorrhage, CTCAE PT NCI Grade 3 Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56412 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Pharyngeal Hemorrhage, CTCAE Grade 3 Pharyngeal hemorrhage 10055315 C56412 Grade 3 Pharyngeal hemorrhage Grade 3 Pharyngeal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Pharyngeal Hemorrhage, CTCAE PT NCI Grade 3 Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56413 >1000 ml of blood evacuated; persistent bleeding (150-200 ml/hr for 2-4 hr); persistent transfusion indicated; elective operative intervention indicated; hospitalization >1000 ml of blood evacuated; persistent bleeding (150-200 ml/hr for 2-4 hr); persistent transfusion indicated; elective operative intervention indicated; hospitalization Grade 3 Pleural Hemorrhage, CTCAE Grade 3 Pleural hemorrhage 10055319 C56413 Grade 3 Pleural hemorrhage Grade 3 Pleural hemorrhage >1000 ml of blood evacuated; persistent bleeding (150-200 ml/hr for 2-4 hr); persistent transfusion indicated; elective operative intervention indicated; hospitalization NCI >1000 ml of blood evacuated; persistent bleeding (150-200 ml/hr for 2-4 hr); persistent transfusion indicated; elective operative intervention indicated; hospitalization CTCAE_v5 Grade 3 Pleural Hemorrhage, CTCAE PT NCI Grade 3 Pleural hemorrhage PT CTCAE_v5 ctcae5:C56414 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Prostatic Hemorrhage, CTCAE Grade 3 Prostatic hemorrhage 10055325 C56414 Grade 3 Prostatic hemorrhage Grade 3 Prostatic hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Prostatic Hemorrhage, CTCAE PT NCI Grade 3 Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56416 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Rectal Hemorrhage, CTCAE Grade 3 Rectal hemorrhage 10038064 C56416 Grade 3 Rectal hemorrhage Grade 3 Rectal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Rectal Hemorrhage, CTCAE PT NCI Grade 3 Rectal hemorrhage PT CTCAE_v5 ctcae5:C56419 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Spermatic Cord Hemorrhage, CTCAE Grade 3 Spermatic cord hemorrhage 10065762 C56419 Grade 3 Spermatic cord hemorrhage Grade 3 Spermatic cord hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Spermatic Cord Hemorrhage, CTCAE PT NCI Grade 3 Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56422 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Testicular Hemorrhage, CTCAE Grade 3 Testicular hemorrhage 10055347 C56422 Grade 3 Testicular hemorrhage Grade 3 Testicular hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Testicular Hemorrhage, CTCAE PT NCI Grade 3 Testicular hemorrhage PT CTCAE_v5 ctcae5:C56423 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Tracheal Hemorrhage, CTCAE Grade 3 Tracheal hemorrhage 10062548 C56423 Grade 3 Tracheal hemorrhage Grade 3 Tracheal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Tracheal Hemorrhage, CTCAE PT NCI Grade 3 Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56428 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Uterine Hemorrhage, CTCAE Grade 3 Uterine hemorrhage 10046789 C56428 Grade 3 Uterine hemorrhage Grade 3 Uterine hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Uterine Hemorrhage, CTCAE PT NCI Grade 3 Uterine hemorrhage PT CTCAE_v5 ctcae5:C56429 Transfusion indicated; invasive intervention indicated; hospitalization Transfusion indicated; invasive intervention indicated; hospitalization Grade 3 Vaginal Hemorrhage, CTCAE Grade 3 Vaginal hemorrhage 10046912 C56429 Grade 3 Vaginal hemorrhage Grade 3 Vaginal hemorrhage Transfusion indicated; invasive intervention indicated; hospitalization NCI Transfusion indicated; invasive intervention indicated; hospitalization CTCAE_v5 Grade 3 Vaginal Hemorrhage, CTCAE PT NCI Grade 3 Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56441 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Esophageal Varices Hemorrhage, CTCAE Grade 4 Esophageal varices hemorrhage 10015453 C56441 Grade 4 Esophageal varices hemorrhage Grade 4 Esophageal varices hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Esophageal Varices Hemorrhage, CTCAE PT NCI Grade 4 Esophageal varices hemorrhage PT CTCAE_v5 ctcae5:C56446 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Hematoma Grade 4 Hematoma, CTCAE 10019428 C56446 Grade 4 Hematoma Grade 4 Hematoma Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Hematoma PT CTCAE_v5 Grade 4 Hematoma, CTCAE PT NCI ctcae5:C56448 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ileal Hemorrhage, CTCAE Grade 4 Ileal hemorrhage 10055287 C56448 Grade 4 Ileal hemorrhage Grade 4 Ileal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ileal Hemorrhage, CTCAE PT NCI Grade 4 Ileal hemorrhage PT CTCAE_v5 ctcae5:C56449 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Jejunal Hemorrhage, CTCAE Grade 4 Jejunal hemorrhage 10055300 C56449 Grade 4 Jejunal hemorrhage Grade 4 Jejunal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Jejunal Hemorrhage, CTCAE PT NCI Grade 4 Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56450 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Renal Hemorrhage, CTCAE Grade 4 Renal hemorrhage 10038463 C56450 Grade 4 Renal hemorrhage Grade 4 Renal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Renal Hemorrhage, CTCAE PT NCI Grade 4 Renal hemorrhage PT CTCAE_v5 ctcae5:C56451 Life-threatening consequences; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening consequences; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Laryngeal Hemorrhage, CTCAE Grade 4 Laryngeal hemorrhage 10065759 C56451 Grade 4 Laryngeal hemorrhage Grade 4 Laryngeal hemorrhage Life-threatening consequences; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening consequences; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Laryngeal Hemorrhage, CTCAE PT NCI Grade 4 Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56455 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Mediastinal Hemorrhage, CTCAE Grade 4 Mediastinal hemorrhage 10056356 C56455 Grade 4 Mediastinal hemorrhage Grade 4 Mediastinal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Mediastinal Hemorrhage, CTCAE PT NCI Grade 4 Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56457 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Oral Hemorrhage, CTCAE Grade 4 Oral hemorrhage 10030980 C56457 Grade 4 Oral hemorrhage Grade 4 Oral hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Oral Hemorrhage, CTCAE PT NCI Grade 4 Oral hemorrhage PT CTCAE_v5 ctcae5:C56458 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ovarian Hemorrhage, CTCAE Grade 4 Ovarian hemorrhage 10065763 C56458 Grade 4 Ovarian hemorrhage Grade 4 Ovarian hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ovarian Hemorrhage, CTCAE PT NCI Grade 4 Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56459 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pancreatic Hemorrhage, CTCAE Grade 4 Pancreatic hemorrhage 10033626 C56459 Grade 4 Pancreatic hemorrhage Grade 4 Pancreatic hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pancreatic Hemorrhage, CTCAE PT NCI Grade 4 Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56461 Life-threatening consequences; intubation or urgent intervention indicated Life-threatening consequences; intubation or urgent intervention indicated Grade 4 Pharyngeal Hemorrhage, CTCAE Grade 4 Pharyngeal hemorrhage 10055315 C56461 Grade 4 Pharyngeal hemorrhage Grade 4 Pharyngeal hemorrhage Life-threatening consequences; intubation or urgent intervention indicated NCI Life-threatening consequences; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Pharyngeal Hemorrhage, CTCAE PT NCI Grade 4 Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56462 Life-threatening consequences; intubation or urgent intervention indicated Life-threatening consequences; intubation or urgent intervention indicated Grade 4 Pleural Hemorrhage, CTCAE Grade 4 Pleural hemorrhage 10055319 C56462 Grade 4 Pleural hemorrhage Grade 4 Pleural hemorrhage Life-threatening consequences; intubation or urgent intervention indicated NCI Life-threatening consequences; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Pleural Hemorrhage, CTCAE PT NCI Grade 4 Pleural hemorrhage PT CTCAE_v5 ctcae5:C56463 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Prostatic Hemorrhage, CTCAE Grade 4 Prostatic hemorrhage 10055325 C56463 Grade 4 Prostatic hemorrhage Grade 4 Prostatic hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Prostatic Hemorrhage, CTCAE PT NCI Grade 4 Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56465 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Rectal Hemorrhage, CTCAE Grade 4 Rectal hemorrhage 10038064 C56465 Grade 4 Rectal hemorrhage Grade 4 Rectal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Rectal Hemorrhage, CTCAE PT NCI Grade 4 Rectal hemorrhage PT CTCAE_v5 ctcae5:C56468 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Spermatic Cord Hemorrhage, CTCAE Grade 4 Spermatic cord hemorrhage 10065762 C56468 Grade 4 Spermatic cord hemorrhage Grade 4 Spermatic cord hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Spermatic Cord Hemorrhage, CTCAE PT NCI Grade 4 Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56471 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Testicular Hemorrhage, CTCAE Grade 4 Testicular hemorrhage 10055347 C56471 Grade 4 Testicular hemorrhage Grade 4 Testicular hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Testicular Hemorrhage, CTCAE PT NCI Grade 4 Testicular hemorrhage PT CTCAE_v5 ctcae5:C56472 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tracheal Hemorrhage, CTCAE Grade 4 Tracheal hemorrhage 10062548 C56472 Grade 4 Tracheal hemorrhage Grade 4 Tracheal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tracheal Hemorrhage, CTCAE PT NCI Grade 4 Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56477 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Uterine Hemorrhage, CTCAE Grade 4 Uterine hemorrhage 10046789 C56477 Grade 4 Uterine hemorrhage Grade 4 Uterine hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Uterine Hemorrhage, CTCAE PT NCI Grade 4 Uterine hemorrhage PT CTCAE_v5 ctcae5:C56478 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vaginal Hemorrhage, CTCAE Grade 4 Vaginal hemorrhage 10046912 C56478 Grade 4 Vaginal hemorrhage Grade 4 Vaginal hemorrhage Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vaginal Hemorrhage, CTCAE PT NCI Grade 4 Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56490 Death Death Grade 5 Esophageal Varices Hemorrhage, CTCAE Grade 5 Esophageal varices hemorrhage 10015453 C56490 Grade 5 Esophageal varices hemorrhage Grade 5 Esophageal varices hemorrhage Death NCI Death CTCAE_v5 Grade 5 Esophageal Varices Hemorrhage, CTCAE PT NCI Grade 5 Esophageal varices hemorrhage PT CTCAE_v5 ctcae5:C56495 Death Death Grade 5 Hematoma Grade 5 Hematoma, CTCAE 10019428 C56495 Grade 5 Hematoma Grade 5 Hematoma Death NCI Death CTCAE_v5 Grade 5 Hematoma PT CTCAE_v5 Grade 5 Hematoma, CTCAE PT NCI ctcae5:C56497 Death Death Grade 5 Ileal Hemorrhage, CTCAE Grade 5 Ileal hemorrhage 10055287 C56497 Grade 5 Ileal hemorrhage Grade 5 Ileal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Ileal Hemorrhage, CTCAE PT NCI Grade 5 Ileal hemorrhage PT CTCAE_v5 ctcae5:C56498 Death Death Grade 5 Jejunal Hemorrhage, CTCAE Grade 5 Jejunal hemorrhage 10055300 C56498 Grade 5 Jejunal hemorrhage Grade 5 Jejunal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Jejunal Hemorrhage, CTCAE PT NCI Grade 5 Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56499 Death Death Grade 5 Renal Hemorrhage, CTCAE Grade 5 Renal hemorrhage 10038463 C56499 Grade 5 Renal hemorrhage Grade 5 Renal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Renal Hemorrhage, CTCAE PT NCI Grade 5 Renal hemorrhage PT CTCAE_v5 ctcae5:C56500 Death Death Grade 5 Laryngeal Hemorrhage, CTCAE Grade 5 Laryngeal hemorrhage 10065759 C56500 Grade 5 Laryngeal hemorrhage Grade 5 Laryngeal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Laryngeal Hemorrhage, CTCAE PT NCI Grade 5 Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56504 Death Death Grade 5 Mediastinal Hemorrhage, CTCAE Grade 5 Mediastinal hemorrhage 10056356 C56504 Grade 5 Mediastinal hemorrhage Grade 5 Mediastinal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Mediastinal Hemorrhage, CTCAE PT NCI Grade 5 Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56506 Death Death Grade 5 Oral Hemorrhage, CTCAE Grade 5 Oral hemorrhage 10030980 C56506 Grade 5 Oral hemorrhage Grade 5 Oral hemorrhage Death NCI Death CTCAE_v5 Grade 5 Oral Hemorrhage, CTCAE PT NCI Grade 5 Oral hemorrhage PT CTCAE_v5 ctcae5:C56507 Death Death Grade 5 Ovarian Hemorrhage, CTCAE Grade 5 Ovarian hemorrhage 10065763 C56507 Grade 5 Ovarian hemorrhage Grade 5 Ovarian hemorrhage Death NCI Death CTCAE_v5 Grade 5 Ovarian Hemorrhage, CTCAE PT NCI Grade 5 Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56508 Death Death Grade 5 Pancreatic Hemorrhage, CTCAE Grade 5 Pancreatic hemorrhage 10033626 C56508 Grade 5 Pancreatic hemorrhage Grade 5 Pancreatic hemorrhage Death NCI Death CTCAE_v5 Grade 5 Pancreatic Hemorrhage, CTCAE PT NCI Grade 5 Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56510 Death Death Grade 5 Pharyngeal Hemorrhage, CTCAE Grade 5 Pharyngeal hemorrhage 10055315 C56510 Grade 5 Pharyngeal hemorrhage Grade 5 Pharyngeal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Hemorrhage, CTCAE PT NCI Grade 5 Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56511 Death Death Grade 5 Pleural Hemorrhage, CTCAE Grade 5 Pleural hemorrhage 10055319 C56511 Grade 5 Pleural hemorrhage Grade 5 Pleural hemorrhage Death NCI Death CTCAE_v5 Grade 5 Pleural Hemorrhage, CTCAE PT NCI Grade 5 Pleural hemorrhage PT CTCAE_v5 ctcae5:C56512 Death Death Grade 5 Prostatic Hemorrhage, CTCAE Grade 5 Prostatic hemorrhage 10055325 C56512 Grade 5 Prostatic hemorrhage Grade 5 Prostatic hemorrhage Death NCI Death CTCAE_v5 Grade 5 Prostatic Hemorrhage, CTCAE PT NCI Grade 5 Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56514 Death Death Grade 5 Rectal Hemorrhage, CTCAE Grade 5 Rectal hemorrhage 10038064 C56514 Grade 5 Rectal hemorrhage Grade 5 Rectal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Rectal Hemorrhage, CTCAE PT NCI Grade 5 Rectal hemorrhage PT CTCAE_v5 ctcae5:C56517 Death Death Grade 5 Spermatic Cord Hemorrhage, CTCAE Grade 5 Spermatic cord hemorrhage 10065762 C56517 Grade 5 Spermatic cord hemorrhage Grade 5 Spermatic cord hemorrhage Death NCI Death CTCAE_v5 Grade 5 Spermatic Cord Hemorrhage, CTCAE PT NCI Grade 5 Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56520 Death Death Grade 5 Testicular Hemorrhage, CTCAE Grade 5 Testicular hemorrhage 10055347 C56520 Grade 5 Testicular hemorrhage Grade 5 Testicular hemorrhage Death NCI Death CTCAE_v5 Grade 5 Testicular Hemorrhage, CTCAE PT NCI Grade 5 Testicular hemorrhage PT CTCAE_v5 ctcae5:C56521 Death Death Grade 5 Tracheal Hemorrhage, CTCAE Grade 5 Tracheal hemorrhage 10062548 C56521 Grade 5 Tracheal hemorrhage Grade 5 Tracheal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Tracheal Hemorrhage, CTCAE PT NCI Grade 5 Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56526 Death Death Grade 5 Uterine Hemorrhage, CTCAE Grade 5 Uterine hemorrhage 10046789 C56526 Grade 5 Uterine hemorrhage Grade 5 Uterine hemorrhage Death NCI Death CTCAE_v5 Grade 5 Uterine Hemorrhage, CTCAE PT NCI Grade 5 Uterine hemorrhage PT CTCAE_v5 ctcae5:C56527 Death Death Grade 5 Vaginal Hemorrhage, CTCAE Grade 5 Vaginal hemorrhage 10046912 C56527 Grade 5 Vaginal hemorrhage Grade 5 Vaginal hemorrhage Death NCI Death CTCAE_v5 Grade 5 Vaginal Hemorrhage, CTCAE PT NCI Grade 5 Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56539 A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. Hematoma Hematoma, CTCAE 10019428 C56539 Hematoma Hematoma A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. NCI A disorder characterized by a localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. CTCAE_v5 Hematoma PT CTCAE_v5 Hematoma, CTCAE PT NCI ctcae5:C56542 A disorder characterized by bleeding from the ileal wall. A disorder characterized by bleeding from the ileal wall. Ileal Hemorrhage, CTCAE Ileal hemorrhage 10055287 C56542 Ileal hemorrhage Ileal hemorrhage A disorder characterized by bleeding from the ileal wall. NCI A disorder characterized by bleeding from the ileal wall. CTCAE_v5 Ileal Hemorrhage, CTCAE PT NCI Ileal hemorrhage PT CTCAE_v5 ctcae5:C56543 A disorder characterized by bleeding from the jejunal wall. A disorder characterized by bleeding from the jejunal wall. Jejunal Hemorrhage, CTCAE Jejunal hemorrhage 10055300 C56543 Jejunal hemorrhage Jejunal hemorrhage A disorder characterized by bleeding from the jejunal wall. NCI A disorder characterized by bleeding from the jejunal wall. CTCAE_v5 Jejunal Hemorrhage, CTCAE PT NCI Jejunal hemorrhage PT CTCAE_v5 ctcae5:C56544 A disorder characterized by bleeding from the kidney. A disorder characterized by bleeding from the kidney. Renal Hemorrhage, CTCAE Renal hemorrhage 10038463 C56544 Renal hemorrhage Renal hemorrhage A disorder characterized by bleeding from the kidney. NCI A disorder characterized by bleeding from the kidney. CTCAE_v5 Renal Hemorrhage, CTCAE PT NCI Renal hemorrhage PT CTCAE_v5 ctcae5:C56545 A disorder characterized by bleeding from the larynx. A disorder characterized by bleeding from the larynx. Laryngeal Hemorrhage, CTCAE Laryngeal hemorrhage 10065759 C56545 Laryngeal hemorrhage Laryngeal hemorrhage A disorder characterized by bleeding from the larynx. NCI A disorder characterized by bleeding from the larynx. CTCAE_v5 Laryngeal Hemorrhage, CTCAE PT NCI Laryngeal hemorrhage PT CTCAE_v5 ctcae5:C56549 A disorder characterized by bleeding from the mediastinum. A disorder characterized by bleeding from the mediastinum. Mediastinal Hemorrhage, CTCAE Mediastinal hemorrhage 10056356 C56549 Mediastinal hemorrhage Mediastinal hemorrhage A disorder characterized by bleeding from the mediastinum. NCI A disorder characterized by bleeding from the mediastinum. CTCAE_v5 Mediastinal Hemorrhage, CTCAE PT NCI Mediastinal hemorrhage PT CTCAE_v5 ctcae5:C56551 A disorder characterized by bleeding from the mouth. A disorder characterized by bleeding from the mouth. Oral Hemorrhage, CTCAE Oral hemorrhage 10030980 C56551 Oral hemorrhage Oral hemorrhage A disorder characterized by bleeding from the mouth. NCI A disorder characterized by bleeding from the mouth. CTCAE_v5 Oral Hemorrhage, CTCAE PT NCI Oral hemorrhage PT CTCAE_v5 ctcae5:C56552 A disorder characterized by bleeding from the prostate gland. A disorder characterized by bleeding from the prostate gland. Prostatic Hemorrhage, CTCAE Prostatic hemorrhage 10055325 C56552 Prostatic hemorrhage Prostatic hemorrhage A disorder characterized by bleeding from the prostate gland. NCI A disorder characterized by bleeding from the prostate gland. CTCAE_v5 Prostatic Hemorrhage, CTCAE PT NCI Prostatic hemorrhage PT CTCAE_v5 ctcae5:C56553 A disorder characterized by bleeding from the ovary. A disorder characterized by bleeding from the ovary. Ovarian Hemorrhage, CTCAE Ovarian hemorrhage 10065763 C56553 Ovarian hemorrhage Ovarian hemorrhage A disorder characterized by bleeding from the ovary. NCI A disorder characterized by bleeding from the ovary. CTCAE_v5 Ovarian Hemorrhage, CTCAE PT NCI Ovarian hemorrhage PT CTCAE_v5 ctcae5:C56554 A disorder characterized by bleeding from the pancreas. A disorder characterized by bleeding from the pancreas. Pancreatic Hemorrhage, CTCAE Pancreatic hemorrhage 10033626 C56554 Pancreatic hemorrhage Pancreatic hemorrhage A disorder characterized by bleeding from the pancreas. NCI A disorder characterized by bleeding from the pancreas. CTCAE_v5 Pancreatic Hemorrhage, CTCAE PT NCI Pancreatic hemorrhage PT CTCAE_v5 ctcae5:C56557 A disorder characterized by bleeding from the pharynx. A disorder characterized by bleeding from the pharynx. Pharyngeal Hemorrhage, CTCAE Pharyngeal hemorrhage 10055315 C56557 Pharyngeal hemorrhage Pharyngeal hemorrhage A disorder characterized by bleeding from the pharynx. NCI A disorder characterized by bleeding from the pharynx. CTCAE_v5 Pharyngeal Hemorrhage, CTCAE PT NCI Pharyngeal hemorrhage PT CTCAE_v5 ctcae5:C56558 A disorder characterized by bleeding from the pleural cavity. A disorder characterized by bleeding from the pleural cavity. Pleural Hemorrhage, CTCAE Pleural hemorrhage 10055319 C56558 Pleural hemorrhage Pleural hemorrhage A disorder characterized by bleeding from the pleural cavity. NCI A disorder characterized by bleeding from the pleural cavity. CTCAE_v5 Pleural Hemorrhage, CTCAE PT NCI Pleural hemorrhage PT CTCAE_v5 ctcae5:C56560 A disorder characterized by bleeding from the rectal wall and discharged from the anus. A disorder characterized by bleeding from the rectal wall and discharged from the anus. Rectal Hemorrhage, CTCAE Rectal hemorrhage 10038064 C56560 Rectal hemorrhage Rectal hemorrhage A disorder characterized by bleeding from the rectal wall and discharged from the anus. NCI A disorder characterized by bleeding from the rectal wall and discharged from the anus. CTCAE_v5 Rectal Hemorrhage, CTCAE PT NCI Rectal hemorrhage PT CTCAE_v5 ctcae5:C56563 A disorder characterized by bleeding from the spermatic cord. A disorder characterized by bleeding from the spermatic cord. Spermatic Cord Hemorrhage, CTCAE Spermatic cord hemorrhage 10065762 C56563 Spermatic cord hemorrhage Spermatic cord hemorrhage A disorder characterized by bleeding from the spermatic cord. NCI A disorder characterized by bleeding from the spermatic cord. CTCAE_v5 Spermatic Cord Hemorrhage, CTCAE PT NCI Spermatic cord hemorrhage PT CTCAE_v5 ctcae5:C56566 A disorder characterized by bleeding from the testis. A disorder characterized by bleeding from the testis. Testicular Hemorrhage, CTCAE Testicular hemorrhage 10055347 C56566 Testicular hemorrhage Testicular hemorrhage A disorder characterized by bleeding from the testis. NCI A disorder characterized by bleeding from the testis. CTCAE_v5 Testicular Hemorrhage, CTCAE PT NCI Testicular hemorrhage PT CTCAE_v5 ctcae5:C56567 A disorder characterized by bleeding from the trachea. A disorder characterized by bleeding from the trachea. Tracheal Hemorrhage, CTCAE Tracheal hemorrhage 10062548 C56567 Tracheal hemorrhage Tracheal hemorrhage A disorder characterized by bleeding from the trachea. NCI A disorder characterized by bleeding from the trachea. CTCAE_v5 Tracheal Hemorrhage, CTCAE PT NCI Tracheal hemorrhage PT CTCAE_v5 ctcae5:C56572 A disorder characterized by bleeding from the uterus. A disorder characterized by bleeding from the uterus. Uterine Hemorrhage, CTCAE Uterine hemorrhage 10046789 C56572 Uterine hemorrhage Uterine hemorrhage A disorder characterized by bleeding from the uterus. NCI A disorder characterized by bleeding from the uterus. CTCAE_v5 Uterine Hemorrhage, CTCAE PT NCI Uterine hemorrhage PT CTCAE_v5 ctcae5:C56573 A disorder characterized by bleeding from the vagina. A disorder characterized by bleeding from the vagina. Vaginal Hemorrhage, CTCAE Vaginal hemorrhage 10046912 C56573 Vaginal hemorrhage Vaginal hemorrhage A disorder characterized by bleeding from the vagina. NCI A disorder characterized by bleeding from the vagina. CTCAE_v5 Vaginal Hemorrhage, CTCAE PT NCI Vaginal hemorrhage PT CTCAE_v5 ctcae5:C56579 Symptomatic; medical intervention indicated Symptomatic; medical intervention indicated Grade 2 Cholecystitis Grade 2 Cholecystitis, CTCAE 10008612 C56579 Grade 2 Cholecystitis Grade 2 Cholecystitis Symptomatic; medical intervention indicated NCI Symptomatic; medical intervention indicated CTCAE_v5 Grade 2 Cholecystitis PT CTCAE_v5 Grade 2 Cholecystitis, CTCAE PT NCI ctcae5:C56583 Enzyme elevation; radiologic findings only Enzyme elevation; radiologic findings only Grade 2 Pancreatitis Grade 2 Pancreatitis, CTCAE 10033645 C56583 Grade 2 Pancreatitis Grade 2 Pancreatitis Enzyme elevation; radiologic findings only NCI Enzyme elevation; radiologic findings only CTCAE_v5 Grade 2 Pancreatitis PT CTCAE_v5 Grade 2 Pancreatitis, CTCAE PT NCI ctcae5:C56584 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Cholecystitis Grade 3 Cholecystitis, CTCAE 10008612 C56584 Grade 3 Cholecystitis Grade 3 Cholecystitis Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Cholecystitis PT CTCAE_v5 Grade 3 Cholecystitis, CTCAE PT NCI ctcae5:C56588 Severe pain; vomiting; medical intervention indicated (e.g., analgesia, nutritional support) Severe pain; vomiting; medical intervention indicated (e.g., analgesia, nutritional support) Grade 3 Pancreatitis Grade 3 Pancreatitis, CTCAE 10033645 C56588 Grade 3 Pancreatitis Grade 3 Pancreatitis Severe pain; vomiting; medical intervention indicated (e.g., analgesia, nutritional support) NCI Severe pain; vomiting; medical intervention indicated (e.g., analgesia, nutritional support) CTCAE_v5 Grade 3 Pancreatitis PT CTCAE_v5 Grade 3 Pancreatitis, CTCAE PT NCI ctcae5:C56589 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Cholecystitis Grade 4 Cholecystitis, CTCAE 10008612 C56589 Grade 4 Cholecystitis Grade 4 Cholecystitis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Cholecystitis PT CTCAE_v5 Grade 4 Cholecystitis, CTCAE PT NCI ctcae5:C56593 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pancreatitis Grade 4 Pancreatitis, CTCAE 10033645 C56593 Grade 4 Pancreatitis Grade 4 Pancreatitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pancreatitis PT CTCAE_v5 Grade 4 Pancreatitis, CTCAE PT NCI ctcae5:C56594 Death Death Grade 5 Cholecystitis Grade 5 Cholecystitis, CTCAE 10008612 C56594 Grade 5 Cholecystitis Grade 5 Cholecystitis Death NCI Death CTCAE_v5 Grade 5 Cholecystitis PT CTCAE_v5 Grade 5 Cholecystitis, CTCAE PT NCI ctcae5:C56598 Death Death Grade 5 Pancreatitis Grade 5 Pancreatitis, CTCAE 10033645 C56598 Grade 5 Pancreatitis Grade 5 Pancreatitis Death NCI Death CTCAE_v5 Grade 5 Pancreatitis PT CTCAE_v5 Grade 5 Pancreatitis, CTCAE PT NCI ctcae5:C56606 Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated Grade 1 Retinoic Acid Syndrome, CTCAE Grade 1 Retinoic acid syndrome 10038921 C56606 Grade 1 Retinoic acid syndrome Grade 1 Retinoic acid syndrome Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated NCI Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated CTCAE_v5 Grade 1 Retinoic Acid Syndrome, CTCAE PT NCI Grade 1 Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56611 Moderate signs or symptoms; steroids indicated Moderate signs or symptoms; steroids indicated Grade 2 Retinoic Acid Syndrome, CTCAE Grade 2 Retinoic acid syndrome 10038921 C56611 Grade 2 Retinoic acid syndrome Grade 2 Retinoic acid syndrome Moderate signs or symptoms; steroids indicated NCI Moderate signs or symptoms; steroids indicated CTCAE_v5 Grade 2 Retinoic Acid Syndrome, CTCAE PT NCI Grade 2 Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56617 Severe symptoms; hospitalization indicated Severe symptoms; hospitalization indicated Grade 3 Retinoic Acid Syndrome, CTCAE Grade 3 Retinoic acid syndrome 10038921 C56617 Grade 3 Retinoic acid syndrome Grade 3 Retinoic acid syndrome Severe symptoms; hospitalization indicated NCI Severe symptoms; hospitalization indicated CTCAE_v5 Grade 3 Retinoic Acid Syndrome, CTCAE PT NCI Grade 3 Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56620 Present Present Grade 3 Tumor Lysis Syndrome, CTCAE Grade 3 Tumor lysis syndrome 10045152 C56620 Grade 3 Tumor lysis syndrome Grade 3 Tumor lysis syndrome Present NCI Present CTCAE_v5 Grade 3 Tumor Lysis Syndrome, CTCAE PT NCI Grade 3 Tumor lysis syndrome PT CTCAE_v5 ctcae5:C56623 Life-threatening consequences; ventilatory support indicated Life-threatening consequences; ventilatory support indicated Grade 4 Retinoic Acid Syndrome, CTCAE Grade 4 Retinoic acid syndrome 10038921 C56623 Grade 4 Retinoic acid syndrome Grade 4 Retinoic acid syndrome Life-threatening consequences; ventilatory support indicated NCI Life-threatening consequences; ventilatory support indicated CTCAE_v5 Grade 4 Retinoic Acid Syndrome, CTCAE PT NCI Grade 4 Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56629 Death Death Grade 5 Retinoic Acid Syndrome, CTCAE Grade 5 Retinoic acid syndrome 10038921 C56629 Grade 5 Retinoic acid syndrome Grade 5 Retinoic acid syndrome Death NCI Death CTCAE_v5 Grade 5 Retinoic Acid Syndrome, CTCAE PT NCI Grade 5 Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56632 Death Death Grade 5 Tumor Lysis Syndrome, CTCAE Grade 5 Tumor lysis syndrome 10045152 C56632 Grade 5 Tumor lysis syndrome Grade 5 Tumor lysis syndrome Death NCI Death CTCAE_v5 Grade 5 Tumor Lysis Syndrome, CTCAE PT NCI Grade 5 Tumor lysis syndrome PT CTCAE_v5 ctcae5:C56635 A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. Retinoic Acid Syndrome, CTCAE Retinoic acid syndrome 10038921 C56635 Retinoic acid syndrome Retinoic acid syndrome A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. NCI A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid. CTCAE_v5 Retinoic Acid Syndrome, CTCAE PT NCI Retinoic acid syndrome PT CTCAE_v5 ctcae5:C56644 Asymptomatic diagnostic finding; intervention not indicated Asymptomatic diagnostic finding; intervention not indicated Grade 1 Injury To Inferior Vena Cava, CTCAE Grade 1 Injury to inferior vena cava 10022213 C56644 Grade 1 Injury to inferior vena cava Grade 1 Injury to inferior vena cava Asymptomatic diagnostic finding; intervention not indicated NCI Asymptomatic diagnostic finding; intervention not indicated CTCAE_v5 Grade 1 Injury To Inferior Vena Cava, CTCAE PT NCI Grade 1 Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56659 Symptomatic; repair or revision not indicated Symptomatic; repair or revision not indicated Grade 2 Injury To Inferior Vena Cava, CTCAE Grade 2 Injury to inferior vena cava 10022213 C56659 Grade 2 Injury to inferior vena cava Grade 2 Injury to inferior vena cava Symptomatic; repair or revision not indicated NCI Symptomatic; repair or revision not indicated CTCAE_v5 Grade 2 Injury To Inferior Vena Cava, CTCAE PT NCI Grade 2 Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56680 Severe symptoms; limiting self care ADL; repair or revision indicated Severe symptoms; limiting self care ADL; repair or revision indicated Grade 3 Injury To Inferior Vena Cava, CTCAE Grade 3 Injury to inferior vena cava 10022213 C56680 Grade 3 Injury to inferior vena cava Grade 3 Injury to inferior vena cava Severe symptoms; limiting self care ADL; repair or revision indicated NCI Severe symptoms; limiting self care ADL; repair or revision indicated CTCAE_v5 Grade 3 Injury To Inferior Vena Cava, CTCAE PT NCI Grade 3 Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56700 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Injury To Inferior Vena Cava, CTCAE Grade 4 Injury to inferior vena cava 10022213 C56700 Grade 4 Injury to inferior vena cava Grade 4 Injury to inferior vena cava Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Injury To Inferior Vena Cava, CTCAE PT NCI Grade 4 Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56719 Death Death Grade 5 Injury To Inferior Vena Cava, CTCAE Grade 5 Injury to inferior vena cava 10022213 C56719 Grade 5 Injury to inferior vena cava Grade 5 Injury to inferior vena cava Death NCI Death CTCAE_v5 Grade 5 Injury To Inferior Vena Cava, CTCAE PT NCI Grade 5 Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56735 A finding of damage to the inferior vena cava. A finding of damage to the inferior vena cava. Injury To Inferior Vena Cava, CTCAE Injury to inferior vena cava 10022213 C56735 Injury to inferior vena cava Injury to inferior vena cava A finding of damage to the inferior vena cava. NCI A finding of damage to the inferior vena cava. CTCAE_v5 Injury To Inferior Vena Cava, CTCAE PT NCI Injury to inferior vena cava PT CTCAE_v5 ctcae5:C56763 Intervention not indicated Intervention not indicated Grade 1 Bladder Spasm, CTCAE Grade 1 Bladder spasm 10048994 C56763 Grade 1 Bladder spasm Grade 1 Bladder spasm Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 1 Bladder Spasm, CTCAE PT NCI Grade 1 Bladder spasm PT CTCAE_v5 ctcae5:C56767 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Fallopian Tube Obstruction, CTCAE Grade 1 Fallopian tube obstruction 10065789 C56767 Grade 1 Fallopian tube obstruction Grade 1 Fallopian tube obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Fallopian Tube Obstruction, CTCAE PT NCI Grade 1 Fallopian tube obstruction PT CTCAE_v5 ctcae5:C56784 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Spermatic Cord Obstruction, CTCAE Grade 1 Spermatic cord obstruction 10065805 C56784 Grade 1 Spermatic cord obstruction Grade 1 Spermatic cord obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Spermatic Cord Obstruction, CTCAE PT NCI Grade 1 Spermatic cord obstruction PT CTCAE_v5 ctcae5:C56803 Occasional (e.g., with coughing, sneezing, etc.), pads not indicated Occasional (e.g., with coughing, sneezing, etc.), pads not indicated Grade 1 Urinary Incontinence, CTCAE Grade 1 Urinary incontinence 10046543 C56803 Grade 1 Urinary incontinence Grade 1 Urinary incontinence Occasional (e.g., with coughing, sneezing, etc.), pads not indicated NCI Occasional (e.g., with coughing, sneezing, etc.), pads not indicated CTCAE_v5 Grade 1 Urinary Incontinence, CTCAE PT NCI Grade 1 Urinary incontinence PT CTCAE_v5 ctcae5:C56804 Urinary, suprapubic or intermittent catheter placement not indicated; able to void with some residual Urinary, suprapubic or intermittent catheter placement not indicated; able to void with some residual Grade 1 Urinary Retention, CTCAE Grade 1 Urinary retention 10046555 C56804 Grade 1 Urinary retention Grade 1 Urinary retention Urinary, suprapubic or intermittent catheter placement not indicated; able to void with some residual NCI Urinary, suprapubic or intermittent catheter placement not indicated; able to void with some residual CTCAE_v5 Grade 1 Urinary Retention, CTCAE PT NCI Grade 1 Urinary retention PT CTCAE_v5 ctcae5:C56811 Asymptomatic Asymptomatic Grade 1 Vaginal Fistula, CTCAE Grade 1 Vaginal fistula 10065813 C56811 Grade 1 Vaginal fistula Grade 1 Vaginal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Vaginal Fistula, CTCAE PT NCI Grade 1 Vaginal fistula PT CTCAE_v5 ctcae5:C56823 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Bladder Perforation, CTCAE Grade 2 Bladder perforation 10063575 C56823 Grade 2 Bladder perforation Grade 2 Bladder perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Bladder Perforation, CTCAE PT NCI Grade 2 Bladder perforation PT CTCAE_v5 ctcae5:C56824 Antispasmodics indicated Antispasmodics indicated Grade 2 Bladder Spasm, CTCAE Grade 2 Bladder spasm 10048994 C56824 Grade 2 Bladder spasm Grade 2 Bladder spasm Antispasmodics indicated NCI Antispasmodics indicated CTCAE_v5 Grade 2 Bladder Spasm, CTCAE PT NCI Grade 2 Bladder spasm PT CTCAE_v5 ctcae5:C56828 Symptomatic; elective intervention indicated Symptomatic; elective intervention indicated Grade 2 Fallopian Tube Obstruction, CTCAE Grade 2 Fallopian tube obstruction 10065789 C56828 Grade 2 Fallopian tube obstruction Grade 2 Fallopian tube obstruction Symptomatic; elective intervention indicated NCI Symptomatic; elective intervention indicated CTCAE_v5 Grade 2 Fallopian Tube Obstruction, CTCAE PT NCI Grade 2 Fallopian tube obstruction PT CTCAE_v5 ctcae5:C56829 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Fallopian Tube Perforation, CTCAE Grade 2 Fallopian tube perforation 10065790 C56829 Grade 2 Fallopian tube perforation Grade 2 Fallopian tube perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Fallopian Tube Perforation, CTCAE PT NCI Grade 2 Fallopian tube perforation PT CTCAE_v5 ctcae5:C56845 Symptomatic; elective intervention indicated Symptomatic; elective intervention indicated Grade 2 Spermatic Cord Obstruction, CTCAE Grade 2 Spermatic cord obstruction 10065805 C56845 Grade 2 Spermatic cord obstruction Grade 2 Spermatic cord obstruction Symptomatic; elective intervention indicated NCI Symptomatic; elective intervention indicated CTCAE_v5 Grade 2 Spermatic Cord Obstruction, CTCAE PT NCI Grade 2 Spermatic cord obstruction PT CTCAE_v5 ctcae5:C56864 Spontaneous; pads indicated; limiting instrumental ADL Spontaneous; pads indicated; limiting instrumental ADL Grade 2 Urinary Incontinence, CTCAE Grade 2 Urinary incontinence 10046543 C56864 Grade 2 Urinary incontinence Grade 2 Urinary incontinence Spontaneous; pads indicated; limiting instrumental ADL NCI Spontaneous; pads indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Urinary Incontinence, CTCAE PT NCI Grade 2 Urinary incontinence PT CTCAE_v5 ctcae5:C56865 Placement of urinary, suprapubic or intermittent catheter placement indicated; medication indicated Placement of urinary, suprapubic or intermittent catheter placement indicated; medication indicated Grade 2 Urinary Retention, CTCAE Grade 2 Urinary retention 10046555 C56865 Grade 2 Urinary retention Grade 2 Urinary retention Placement of urinary, suprapubic or intermittent catheter placement indicated; medication indicated NCI Placement of urinary, suprapubic or intermittent catheter placement indicated; medication indicated CTCAE_v5 Grade 2 Urinary Retention, CTCAE PT NCI Grade 2 Urinary retention PT CTCAE_v5 ctcae5:C56871 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Vaginal Fistula, CTCAE Grade 2 Vaginal fistula 10065813 C56871 Grade 2 Vaginal fistula Grade 2 Vaginal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Vaginal Fistula, CTCAE PT NCI Grade 2 Vaginal fistula PT CTCAE_v5 ctcae5:C56883 Invasive intervention indicated Invasive intervention indicated Grade 3 Bladder Perforation, CTCAE Grade 3 Bladder perforation 10063575 C56883 Grade 3 Bladder perforation Grade 3 Bladder perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Bladder Perforation, CTCAE PT NCI Grade 3 Bladder perforation PT CTCAE_v5 ctcae5:C56884 Hospitalization indicated Hospitalization indicated Grade 3 Bladder Spasm, CTCAE Grade 3 Bladder spasm 10048994 C56884 Grade 3 Bladder spasm Grade 3 Bladder spasm Hospitalization indicated NCI Hospitalization indicated CTCAE_v5 Grade 3 Bladder Spasm, CTCAE PT NCI Grade 3 Bladder spasm PT CTCAE_v5 ctcae5:C56888 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Fallopian Tube Obstruction, CTCAE Grade 3 Fallopian tube obstruction 10065789 C56888 Grade 3 Fallopian tube obstruction Grade 3 Fallopian tube obstruction Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Fallopian Tube Obstruction, CTCAE PT NCI Grade 3 Fallopian tube obstruction PT CTCAE_v5 ctcae5:C56889 Invasive intervention indicated Invasive intervention indicated Grade 3 Fallopian Tube Perforation, CTCAE Grade 3 Fallopian tube perforation 10065790 C56889 Grade 3 Fallopian tube perforation Grade 3 Fallopian tube perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Fallopian Tube Perforation, CTCAE PT NCI Grade 3 Fallopian tube perforation PT CTCAE_v5 ctcae5:C56906 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Spermatic Cord Obstruction, CTCAE Grade 3 Spermatic cord obstruction 10065805 C56906 Grade 3 Spermatic cord obstruction Grade 3 Spermatic cord obstruction Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Spermatic Cord Obstruction, CTCAE PT NCI Grade 3 Spermatic cord obstruction PT CTCAE_v5 ctcae5:C56925 Intervention indicated (e.g., clamp, collagen injections); operative intervention indicated; limiting self care ADL Intervention indicated (e.g., clamp, collagen injections); operative intervention indicated; limiting self care ADL Grade 3 Urinary Incontinence, CTCAE Grade 3 Urinary incontinence 10046543 C56925 Grade 3 Urinary incontinence Grade 3 Urinary incontinence Intervention indicated (e.g., clamp, collagen injections); operative intervention indicated; limiting self care ADL NCI Intervention indicated (e.g., clamp, collagen injections); operative intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Urinary Incontinence, CTCAE PT NCI Grade 3 Urinary incontinence PT CTCAE_v5 ctcae5:C56926 Elective invasive intervention indicated; substantial loss of affected kidney function or mass Elective invasive intervention indicated; substantial loss of affected kidney function or mass Grade 3 Urinary Retention, CTCAE Grade 3 Urinary retention 10046555 C56926 Grade 3 Urinary retention Grade 3 Urinary retention Elective invasive intervention indicated; substantial loss of affected kidney function or mass NCI Elective invasive intervention indicated; substantial loss of affected kidney function or mass CTCAE_v5 Grade 3 Urinary Retention, CTCAE PT NCI Grade 3 Urinary retention PT CTCAE_v5 ctcae5:C56932 Invasive intervention indicated Invasive intervention indicated Grade 3 Vaginal Fistula, CTCAE Grade 3 Vaginal fistula 10065813 C56932 Grade 3 Vaginal fistula Grade 3 Vaginal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Vaginal Fistula, CTCAE PT NCI Grade 3 Vaginal fistula PT CTCAE_v5 ctcae5:C56944 Life-threatening consequences; organ failure; urgent operative intervention indicated Life-threatening consequences; organ failure; urgent operative intervention indicated Grade 4 Bladder Perforation, CTCAE Grade 4 Bladder perforation 10063575 C56944 Grade 4 Bladder perforation Grade 4 Bladder perforation Life-threatening consequences; organ failure; urgent operative intervention indicated NCI Life-threatening consequences; organ failure; urgent operative intervention indicated CTCAE_v5 Grade 4 Bladder Perforation, CTCAE PT NCI Grade 4 Bladder perforation PT CTCAE_v5 ctcae5:C56950 Life-threatening consequences; urgent operative intervention indicated (e.g., organ resection) Life-threatening consequences; urgent operative intervention indicated (e.g., organ resection) Grade 4 Fallopian Tube Perforation, CTCAE Grade 4 Fallopian tube perforation 10065790 C56950 Grade 4 Fallopian tube perforation Grade 4 Fallopian tube perforation Life-threatening consequences; urgent operative intervention indicated (e.g., organ resection) NCI Life-threatening consequences; urgent operative intervention indicated (e.g., organ resection) CTCAE_v5 Grade 4 Fallopian Tube Perforation, CTCAE PT NCI Grade 4 Fallopian tube perforation PT CTCAE_v5 ctcae5:C56985 Life-threatening consequences; organ failure; urgent operative intervention indicated Life-threatening consequences; organ failure; urgent operative intervention indicated Grade 4 Urinary Retention, CTCAE Grade 4 Urinary retention 10046555 C56985 Grade 4 Urinary retention Grade 4 Urinary retention Life-threatening consequences; organ failure; urgent operative intervention indicated NCI Life-threatening consequences; organ failure; urgent operative intervention indicated CTCAE_v5 Grade 4 Urinary Retention, CTCAE PT NCI Grade 4 Urinary retention PT CTCAE_v5 ctcae5:C56991 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Vaginal Fistula, CTCAE Grade 4 Vaginal fistula 10065813 C56991 Grade 4 Vaginal fistula Grade 4 Vaginal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Vaginal Fistula, CTCAE PT NCI Grade 4 Vaginal fistula PT CTCAE_v5 ctcae5:C57003 Death Death Grade 5 Bladder Perforation, CTCAE Grade 5 Bladder perforation 10063575 C57003 Grade 5 Bladder perforation Grade 5 Bladder perforation Death NCI Death CTCAE_v5 Grade 5 Bladder Perforation, CTCAE PT NCI Grade 5 Bladder perforation PT CTCAE_v5 ctcae5:C57008 Death Death Grade 5 Fallopian Tube Perforation, CTCAE Grade 5 Fallopian tube perforation 10065790 C57008 Grade 5 Fallopian tube perforation Grade 5 Fallopian tube perforation Death NCI Death CTCAE_v5 Grade 5 Fallopian Tube Perforation, CTCAE PT NCI Grade 5 Fallopian tube perforation PT CTCAE_v5 ctcae5:C57042 Death Death Grade 5 Urinary Retention, CTCAE Grade 5 Urinary retention 10046555 C57042 Grade 5 Urinary retention Grade 5 Urinary retention Death NCI Death CTCAE_v5 Grade 5 Urinary Retention, CTCAE PT NCI Grade 5 Urinary retention PT CTCAE_v5 ctcae5:C57048 Death Death Grade 5 Vaginal Fistula, CTCAE Grade 5 Vaginal fistula 10065813 C57048 Grade 5 Vaginal fistula Grade 5 Vaginal fistula Death NCI Death CTCAE_v5 Grade 5 Vaginal Fistula, CTCAE PT NCI Grade 5 Vaginal fistula PT CTCAE_v5 ctcae5:C57097 A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. Urinary Retention, CTCAE Urinary retention 10046555 C57097 Urinary retention Urinary retention A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. NCI A disorder characterized by accumulation of urine within the bladder because of the inability to urinate. CTCAE_v5 Urinary Retention, CTCAE PT NCI Urinary retention PT CTCAE_v5 ctcae5:C57104 A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. Vaginal Fistula, CTCAE Vaginal fistula 10065813 C57104 Vaginal fistula Vaginal fistula A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the vagina and another organ or anatomic site. CTCAE_v5 Vaginal Fistula, CTCAE PT NCI Vaginal fistula PT CTCAE_v5 ctcae5:C57118 A disorder characterized by a loss of appetite. A disorder characterized by a loss of appetite. Anorexia Anorexia, CTCAE 10002646 C57118 Anorexia Anorexia A disorder characterized by a loss of appetite. NCI A disorder characterized by a loss of appetite. CTCAE_v5 Anorexia PT CTCAE_v5 Anorexia, CTCAE PT NCI ctcae5:C57134 A disorder characterized by inflammation of the colon. A disorder characterized by inflammation of the colon. Colitis Colitis, CTCAE 10009887 C57134 Colitis Colitis A disorder characterized by inflammation of the colon. NCI A disorder characterized by inflammation of the colon. CTCAE_v5 Colitis PT CTCAE_v5 Colitis, CTCAE PT NCI ctcae5:C57141 A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. Constipation Constipation, CTCAE 10010774 C57141 Constipation Constipation A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. NCI A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. CTCAE_v5 Constipation PT CTCAE_v5 Constipation, CTCAE PT NCI ctcae5:C57145 Loss of appetite without alteration in eating habits Loss of appetite without alteration in eating habits Grade 1 Anorexia Grade 1 Anorexia, CTCAE 10002646 C57145 Grade 1 Anorexia Grade 1 Anorexia Loss of appetite without alteration in eating habits NCI Loss of appetite without alteration in eating habits CTCAE_v5 Grade 1 Anorexia PT CTCAE_v5 Grade 1 Anorexia, CTCAE PT NCI ctcae5:C57162 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Colitis Grade 1 Colitis, CTCAE 10009887 C57162 Grade 1 Colitis Grade 1 Colitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Colitis PT CTCAE_v5 Grade 1 Colitis, CTCAE PT NCI ctcae5:C57168 Occasional or intermittent symptoms; occasional use of stool softeners, laxatives, dietary modification, or enema Occasional or intermittent symptoms; occasional use of stool softeners, laxatives, dietary modification, or enema Grade 1 Constipation Grade 1 Constipation, CTCAE 10010774 C57168 Grade 1 Constipation Grade 1 Constipation Occasional or intermittent symptoms; occasional use of stool softeners, laxatives, dietary modification, or enema NCI Occasional or intermittent symptoms; occasional use of stool softeners, laxatives, dietary modification, or enema CTCAE_v5 Grade 1 Constipation PT CTCAE_v5 Grade 1 Constipation, CTCAE PT NCI ctcae5:C57169 Increased oral fluids indicated; dry mucous membranes; diminished skin turgor Increased oral fluids indicated; dry mucous membranes; diminished skin turgor Grade 1 Dehydration Grade 1 Dehydration, CTCAE 10012174 C57169 Grade 1 Dehydration Grade 1 Dehydration Increased oral fluids indicated; dry mucous membranes; diminished skin turgor NCI Increased oral fluids indicated; dry mucous membranes; diminished skin turgor CTCAE_v5 Grade 1 Dehydration PT CTCAE_v5 Grade 1 Dehydration, CTCAE PT NCI ctcae5:C57170 Increase of <4 stools per day over baseline; mild increase in ostomy output compared to baseline Increase of <4 stools per day over baseline; mild increase in ostomy output compared to baseline Grade 1 Diarrhea Grade 1 Diarrhea, CTCAE 10012727 C57170 Grade 1 Diarrhea Grade 1 Diarrhea Increase of <4 stools per day over baseline; mild increase in ostomy output compared to baseline NCI Increase of <4 stools per day over baseline; mild increase in ostomy output compared to baseline CTCAE_v5 Grade 1 Diarrhea PT CTCAE_v5 Grade 1 Diarrhea, CTCAE PT NCI ctcae5:C57171 Asymptomatic Asymptomatic Grade 1 Duodenal Fistula, CTCAE Grade 1 Duodenal fistula 10013828 C57171 Grade 1 Duodenal fistula Grade 1 Duodenal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Duodenal Fistula, CTCAE PT NCI Grade 1 Duodenal fistula PT CTCAE_v5 ctcae5:C57176 Symptomatic, able to eat regular diet Symptomatic, able to eat regular diet Grade 1 Dysphagia Grade 1 Dysphagia, CTCAE 10013950 C57176 Grade 1 Dysphagia Grade 1 Dysphagia Symptomatic, able to eat regular diet NCI Symptomatic, able to eat regular diet CTCAE_v5 Grade 1 Dysphagia PT CTCAE_v5 Grade 1 Dysphagia, CTCAE PT NCI ctcae5:C57178 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Esophagitis Grade 1 Esophagitis, CTCAE 10015461 C57178 Grade 1 Esophagitis Grade 1 Esophagitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Esophagitis PT CTCAE_v5 Grade 1 Esophagitis, CTCAE PT NCI ctcae5:C57179 Asymptomatic Asymptomatic Grade 1 Esophageal Fistula, CTCAE Grade 1 Esophageal fistula 10065851 C57179 Grade 1 Esophageal fistula Grade 1 Esophageal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Esophageal Fistula, CTCAE PT NCI Grade 1 Esophageal fistula PT CTCAE_v5 ctcae5:C57187 Mild symptoms; intervention not indicated Mild symptoms; intervention not indicated Grade 1 Flatulence Grade 1 Flatulence, CTCAE 10016766 C57187 Grade 1 Flatulence Grade 1 Flatulence Mild symptoms; intervention not indicated NCI Mild symptoms; intervention not indicated CTCAE_v5 Grade 1 Flatulence PT CTCAE_v5 Grade 1 Flatulence, CTCAE PT NCI ctcae5:C57188 Asymptomatic Asymptomatic Grade 1 Gallbladder Fistula, CTCAE Grade 1 Gallbladder fistula 10017631 C57188 Grade 1 Gallbladder fistula Grade 1 Gallbladder fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Gallbladder Fistula, CTCAE PT NCI Grade 1 Gallbladder fistula PT CTCAE_v5 ctcae5:C57189 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Gallbladder Obstruction, CTCAE Grade 1 Gallbladder obstruction 10017636 C57189 Grade 1 Gallbladder obstruction Grade 1 Gallbladder obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Gallbladder Obstruction, CTCAE PT NCI Grade 1 Gallbladder obstruction PT CTCAE_v5 ctcae5:C57191 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Gastritis Grade 1 Gastritis, CTCAE 10017853 C57191 Grade 1 Gastritis Grade 1 Gastritis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Gastritis PT CTCAE_v5 Grade 1 Gastritis, CTCAE PT NCI ctcae5:C57196 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Hemorrhoids Grade 1 Hemorrhoids, CTCAE 10019611 C57196 Grade 1 Hemorrhoids Grade 1 Hemorrhoids Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Hemorrhoids PT CTCAE_v5 Grade 1 Hemorrhoids, CTCAE PT NCI ctcae5:C57197 Asymptomatic Asymptomatic Grade 1 Ileal Fistula, CTCAE Grade 1 Ileal fistula 10065728 C57197 Grade 1 Ileal fistula Grade 1 Ileal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Ileal Fistula, CTCAE PT NCI Grade 1 Ileal fistula PT CTCAE_v5 ctcae5:C57198 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ileal Obstruction, CTCAE Grade 1 Ileal obstruction 10065730 C57198 Grade 1 Ileal obstruction Grade 1 Ileal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ileal Obstruction, CTCAE PT NCI Grade 1 Ileal obstruction PT CTCAE_v5 ctcae5:C57201 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Ileal Ulcer, CTCAE Grade 1 Ileal ulcer 10021309 C57201 Grade 1 Ileal ulcer Grade 1 Ileal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Ileal Ulcer, CTCAE PT NCI Grade 1 Ileal ulcer PT CTCAE_v5 ctcae5:C57202 Asymptomatic and radiologic observations only Asymptomatic and radiologic observations only Grade 1 Ileus Grade 1 Ileus, CTCAE 10021328 C57202 Grade 1 Ileus Grade 1 Ileus Asymptomatic and radiologic observations only NCI Asymptomatic and radiologic observations only CTCAE_v5 Grade 1 Ileus PT CTCAE_v5 Grade 1 Ileus, CTCAE PT NCI ctcae5:C57203 Asymptomatic Asymptomatic Grade 1 Jejunal Fistula, CTCAE Grade 1 Jejunal fistula 10065719 C57203 Grade 1 Jejunal fistula Grade 1 Jejunal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Jejunal Fistula, CTCAE PT NCI Grade 1 Jejunal fistula PT CTCAE_v5 ctcae5:C57204 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Jejunal Obstruction, CTCAE Grade 1 Jejunal obstruction 10065732 C57204 Grade 1 Jejunal obstruction Grade 1 Jejunal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Jejunal Obstruction, CTCAE PT NCI Grade 1 Jejunal obstruction PT CTCAE_v5 ctcae5:C57207 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Jejunal Ulcer, CTCAE Grade 1 Jejunal ulcer 10023177 C57207 Grade 1 Jejunal ulcer Grade 1 Jejunal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Jejunal Ulcer, CTCAE PT NCI Grade 1 Jejunal ulcer PT CTCAE_v5 ctcae5:C57213 Loss of appetite without alteration in eating habits Loss of appetite without alteration in eating habits Grade 1 Nausea Grade 1 Nausea, CTCAE 10028813 C57213 Grade 1 Nausea Grade 1 Nausea Loss of appetite without alteration in eating habits NCI Loss of appetite without alteration in eating habits CTCAE_v5 Grade 1 Nausea PT CTCAE_v5 Grade 1 Nausea, CTCAE PT NCI ctcae5:C57218 Asymptomatic Asymptomatic Grade 1 Pancreatic Fistula, CTCAE Grade 1 Pancreatic fistula 10049192 C57218 Grade 1 Pancreatic fistula Grade 1 Pancreatic fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Pancreatic Fistula, CTCAE PT NCI Grade 1 Pancreatic fistula PT CTCAE_v5 ctcae5:C57221 Gingival recession or gingivitis; limited bleeding on probing; mild local bone loss Gingival recession or gingivitis; limited bleeding on probing; mild local bone loss Grade 1 Periodontal Disease, CTCAE Grade 1 Periodontal disease 10034536 C57221 Grade 1 Periodontal disease Grade 1 Periodontal disease Gingival recession or gingivitis; limited bleeding on probing; mild local bone loss NCI Gingival recession or gingivitis; limited bleeding on probing; mild local bone loss CTCAE_v5 Grade 1 Periodontal Disease, CTCAE PT NCI Grade 1 Periodontal disease PT CTCAE_v5 ctcae5:C57222 Asymptomatic Asymptomatic Grade 1 Pharyngeal Fistula, CTCAE Grade 1 Pharyngeal fistula 10034825 C57222 Grade 1 Pharyngeal fistula Grade 1 Pharyngeal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Pharyngeal Fistula, CTCAE PT NCI Grade 1 Pharyngeal fistula PT CTCAE_v5 ctcae5:C57227 Rectal discomfort, intervention not indicated Rectal discomfort, intervention not indicated Grade 1 Proctitis Grade 1 Proctitis, CTCAE 10036774 C57227 Grade 1 Proctitis Grade 1 Proctitis Rectal discomfort, intervention not indicated NCI Rectal discomfort, intervention not indicated CTCAE_v5 Grade 1 Proctitis PT CTCAE_v5 Grade 1 Proctitis, CTCAE PT NCI ctcae5:C57229 Asymptomatic Asymptomatic Grade 1 Rectal Fistula, CTCAE Grade 1 Rectal fistula 10038062 C57229 Grade 1 Rectal fistula Grade 1 Rectal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Rectal Fistula, CTCAE PT NCI Grade 1 Rectal fistula PT CTCAE_v5 ctcae5:C57233 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Rectal Obstruction, CTCAE Grade 1 Rectal obstruction 10065707 C57233 Grade 1 Rectal obstruction Grade 1 Rectal obstruction Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Rectal Obstruction, CTCAE PT NCI Grade 1 Rectal obstruction PT CTCAE_v5 ctcae5:C57236 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Rectal Ulcer, CTCAE Grade 1 Rectal ulcer 10038080 C57236 Grade 1 Rectal ulcer Grade 1 Rectal ulcer Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Rectal Ulcer, CTCAE PT NCI Grade 1 Rectal ulcer PT CTCAE_v5 ctcae5:C57237 Asymptomatic Asymptomatic Grade 1 Salivary Gland Fistula, CTCAE Grade 1 Salivary gland fistula 10039411 C57237 Grade 1 Salivary gland fistula Grade 1 Salivary gland fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Salivary Gland Fistula, CTCAE PT NCI Grade 1 Salivary gland fistula PT CTCAE_v5 ctcae5:C57263 Intervention not indicated Intervention not indicated Grade 1 Vomiting Grade 1 Vomiting, CTCAE 10047700 C57263 Grade 1 Vomiting Grade 1 Vomiting Intervention not indicated NCI Intervention not indicated CTCAE_v5 Grade 1 Vomiting PT CTCAE_v5 Grade 1 Vomiting, CTCAE PT NCI ctcae5:C57268 Oral intake altered without significant weight loss or malnutrition; oral nutritional supplements indicated Oral intake altered without significant weight loss or malnutrition; oral nutritional supplements indicated Grade 2 Anorexia Grade 2 Anorexia, CTCAE 10002646 C57268 Grade 2 Anorexia Grade 2 Anorexia Oral intake altered without significant weight loss or malnutrition; oral nutritional supplements indicated NCI Oral intake altered without significant weight loss or malnutrition; oral nutritional supplements indicated CTCAE_v5 Grade 2 Anorexia PT CTCAE_v5 Grade 2 Anorexia, CTCAE PT NCI ctcae5:C57285 Abdominal pain; mucus or blood in stool Abdominal pain; mucus or blood in stool Grade 2 Colitis Grade 2 Colitis, CTCAE 10009887 C57285 Grade 2 Colitis Grade 2 Colitis Abdominal pain; mucus or blood in stool NCI Abdominal pain; mucus or blood in stool CTCAE_v5 Grade 2 Colitis PT CTCAE_v5 Grade 2 Colitis, CTCAE PT NCI ctcae5:C57291 Persistent symptoms with regular use of laxatives or enemas; limiting instrumental ADL Persistent symptoms with regular use of laxatives or enemas; limiting instrumental ADL Grade 2 Constipation Grade 2 Constipation, CTCAE 10010774 C57291 Grade 2 Constipation Grade 2 Constipation Persistent symptoms with regular use of laxatives or enemas; limiting instrumental ADL NCI Persistent symptoms with regular use of laxatives or enemas; limiting instrumental ADL CTCAE_v5 Grade 2 Constipation PT CTCAE_v5 Grade 2 Constipation, CTCAE PT NCI ctcae5:C57292 IV fluids indicated IV fluids indicated Grade 2 Dehydration Grade 2 Dehydration, CTCAE 10012174 C57292 Grade 2 Dehydration Grade 2 Dehydration IV fluids indicated NCI IV fluids indicated CTCAE_v5 Grade 2 Dehydration PT CTCAE_v5 Grade 2 Dehydration, CTCAE PT NCI ctcae5:C57293 Increase of 4-6 stools per day over baseline; moderate increase in ostomy output compared to baseline; limiting instrumental ADL Increase of 4-6 stools per day over baseline; moderate increase in ostomy output compared to baseline; limiting instrumental ADL Grade 2 Diarrhea Grade 2 Diarrhea, CTCAE 10012727 C57293 Grade 2 Diarrhea Grade 2 Diarrhea Increase of 4-6 stools per day over baseline; moderate increase in ostomy output compared to baseline; limiting instrumental ADL NCI Increase of 4-6 stools per day over baseline; moderate increase in ostomy output compared to baseline; limiting instrumental ADL CTCAE_v5 Grade 2 Diarrhea PT CTCAE_v5 Grade 2 Diarrhea, CTCAE PT NCI ctcae5:C57294 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Duodenal Fistula, CTCAE Grade 2 Duodenal fistula 10013828 C57294 Grade 2 Duodenal fistula Grade 2 Duodenal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Duodenal Fistula, CTCAE PT NCI Grade 2 Duodenal fistula PT CTCAE_v5 ctcae5:C57299 Symptomatic and altered eating/swallowing Symptomatic and altered eating/swallowing Grade 2 Dysphagia Grade 2 Dysphagia, CTCAE 10013950 C57299 Grade 2 Dysphagia Grade 2 Dysphagia Symptomatic and altered eating/swallowing NCI Symptomatic and altered eating/swallowing CTCAE_v5 Grade 2 Dysphagia PT CTCAE_v5 Grade 2 Dysphagia, CTCAE PT NCI ctcae5:C57301 Symptomatic; altered eating/swallowing; oral supplements indicated Symptomatic; altered eating/swallowing; oral supplements indicated Grade 2 Esophagitis Grade 2 Esophagitis, CTCAE 10015461 C57301 Grade 2 Esophagitis Grade 2 Esophagitis Symptomatic; altered eating/swallowing; oral supplements indicated NCI Symptomatic; altered eating/swallowing; oral supplements indicated CTCAE_v5 Grade 2 Esophagitis PT CTCAE_v5 Grade 2 Esophagitis, CTCAE PT NCI ctcae5:C57302 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Esophageal Fistula, CTCAE Grade 2 Esophageal fistula 10065851 C57302 Grade 2 Esophageal fistula Grade 2 Esophageal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Esophageal Fistula, CTCAE PT NCI Grade 2 Esophageal fistula PT CTCAE_v5 ctcae5:C57310 Moderate; persistent; psychosocial sequelae Moderate; persistent; psychosocial sequelae Grade 2 Flatulence Grade 2 Flatulence, CTCAE 10016766 C57310 Grade 2 Flatulence Grade 2 Flatulence Moderate; persistent; psychosocial sequelae NCI Moderate; persistent; psychosocial sequelae CTCAE_v5 Grade 2 Flatulence PT CTCAE_v5 Grade 2 Flatulence, CTCAE PT NCI ctcae5:C57311 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Gallbladder Fistula, CTCAE Grade 2 Gallbladder fistula 10017631 C57311 Grade 2 Gallbladder fistula Grade 2 Gallbladder fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Gallbladder Fistula, CTCAE PT NCI Grade 2 Gallbladder fistula PT CTCAE_v5 ctcae5:C57312 Symptomatic; altered GI function; IV fluids indicated <24 hrs Symptomatic; altered GI function; IV fluids indicated <24 hrs Grade 2 Gallbladder Obstruction, CTCAE Grade 2 Gallbladder obstruction 10017636 C57312 Grade 2 Gallbladder obstruction Grade 2 Gallbladder obstruction Symptomatic; altered GI function; IV fluids indicated <24 hrs NCI Symptomatic; altered GI function; IV fluids indicated <24 hrs CTCAE_v5 Grade 2 Gallbladder Obstruction, CTCAE PT NCI Grade 2 Gallbladder obstruction PT CTCAE_v5 ctcae5:C57314 Symptomatic; altered GI function; medical intervention indicated Symptomatic; altered GI function; medical intervention indicated Grade 2 Gastritis Grade 2 Gastritis, CTCAE 10017853 C57314 Grade 2 Gastritis Grade 2 Gastritis Symptomatic; altered GI function; medical intervention indicated NCI Symptomatic; altered GI function; medical intervention indicated CTCAE_v5 Grade 2 Gastritis PT CTCAE_v5 Grade 2 Gastritis, CTCAE PT NCI ctcae5:C57318 Symptomatic; banding or medical intervention indicated Symptomatic; banding or medical intervention indicated Grade 2 Hemorrhoids Grade 2 Hemorrhoids, CTCAE 10019611 C57318 Grade 2 Hemorrhoids Grade 2 Hemorrhoids Symptomatic; banding or medical intervention indicated NCI Symptomatic; banding or medical intervention indicated CTCAE_v5 Grade 2 Hemorrhoids PT CTCAE_v5 Grade 2 Hemorrhoids, CTCAE PT NCI ctcae5:C57319 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Ileal Fistula, CTCAE Grade 2 Ileal fistula 10065728 C57319 Grade 2 Ileal fistula Grade 2 Ileal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Ileal Fistula, CTCAE PT NCI Grade 2 Ileal fistula PT CTCAE_v5 ctcae5:C57320 Symptomatic; altered GI function; limiting instrumental ADL; naso-gastric tube indicated Symptomatic; altered GI function; limiting instrumental ADL; naso-gastric tube indicated Grade 2 Ileal Obstruction, CTCAE Grade 2 Ileal obstruction 10065730 C57320 Grade 2 Ileal obstruction Grade 2 Ileal obstruction Symptomatic; altered GI function; limiting instrumental ADL; naso-gastric tube indicated NCI Symptomatic; altered GI function; limiting instrumental ADL; naso-gastric tube indicated CTCAE_v5 Grade 2 Ileal Obstruction, CTCAE PT NCI Grade 2 Ileal obstruction PT CTCAE_v5 ctcae5:C57323 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Ileal Ulcer, CTCAE Grade 2 Ileal ulcer 10021309 C57323 Grade 2 Ileal ulcer Grade 2 Ileal ulcer Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Ileal Ulcer, CTCAE PT NCI Grade 2 Ileal ulcer PT CTCAE_v5 ctcae5:C57324 Symptomatic; altered GI function; bowel rest indicated Symptomatic; altered GI function; bowel rest indicated Grade 2 Ileus Grade 2 Ileus, CTCAE 10021328 C57324 Grade 2 Ileus Grade 2 Ileus Symptomatic; altered GI function; bowel rest indicated NCI Symptomatic; altered GI function; bowel rest indicated CTCAE_v5 Grade 2 Ileus PT CTCAE_v5 Grade 2 Ileus, CTCAE PT NCI ctcae5:C57325 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Jejunal Fistula, CTCAE Grade 2 Jejunal fistula 10065719 C57325 Grade 2 Jejunal fistula Grade 2 Jejunal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Jejunal Fistula, CTCAE PT NCI Grade 2 Jejunal fistula PT CTCAE_v5 ctcae5:C57326 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Jejunal Obstruction, CTCAE Grade 2 Jejunal obstruction 10065732 C57326 Grade 2 Jejunal obstruction Grade 2 Jejunal obstruction Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Jejunal Obstruction, CTCAE PT NCI Grade 2 Jejunal obstruction PT CTCAE_v5 ctcae5:C57329 Symptomatic; altered GI function Symptomatic; altered GI function Grade 2 Jejunal Ulcer, CTCAE Grade 2 Jejunal ulcer 10023177 C57329 Grade 2 Jejunal ulcer Grade 2 Jejunal ulcer Symptomatic; altered GI function NCI Symptomatic; altered GI function CTCAE_v5 Grade 2 Jejunal Ulcer, CTCAE PT NCI Grade 2 Jejunal ulcer PT CTCAE_v5 ctcae5:C57335 Altered diet; oral intervention indicated Altered diet; oral intervention indicated Grade 2 Malabsorption Grade 2 Malabsorption, CTCAE 10025476 C57335 Grade 2 Malabsorption Grade 2 Malabsorption Altered diet; oral intervention indicated NCI Altered diet; oral intervention indicated CTCAE_v5 Grade 2 Malabsorption PT CTCAE_v5 Grade 2 Malabsorption, CTCAE PT NCI ctcae5:C57336 Oral intake decreased without significant weight loss, dehydration or malnutrition Oral intake decreased without significant weight loss, dehydration or malnutrition Grade 2 Nausea Grade 2 Nausea, CTCAE 10028813 C57336 Grade 2 Nausea Grade 2 Nausea Oral intake decreased without significant weight loss, dehydration or malnutrition NCI Oral intake decreased without significant weight loss, dehydration or malnutrition CTCAE_v5 Grade 2 Nausea PT CTCAE_v5 Grade 2 Nausea, CTCAE PT NCI ctcae5:C57341 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Pancreatic Fistula, CTCAE Grade 2 Pancreatic fistula 10049192 C57341 Grade 2 Pancreatic fistula Grade 2 Pancreatic fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Pancreatic Fistula, CTCAE PT NCI Grade 2 Pancreatic fistula PT CTCAE_v5 ctcae5:C57344 Moderate gingival recession or gingivitis; multiple sites of bleeding on probing; moderate bone loss Moderate gingival recession or gingivitis; multiple sites of bleeding on probing; moderate bone loss Grade 2 Periodontal Disease, CTCAE Grade 2 Periodontal disease 10034536 C57344 Grade 2 Periodontal disease Grade 2 Periodontal disease Moderate gingival recession or gingivitis; multiple sites of bleeding on probing; moderate bone loss NCI Moderate gingival recession or gingivitis; multiple sites of bleeding on probing; moderate bone loss CTCAE_v5 Grade 2 Periodontal Disease, CTCAE PT NCI Grade 2 Periodontal disease PT CTCAE_v5 ctcae5:C57345 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Pharyngeal Fistula, CTCAE Grade 2 Pharyngeal fistula 10034825 C57345 Grade 2 Pharyngeal fistula Grade 2 Pharyngeal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Pharyngeal Fistula, CTCAE PT NCI Grade 2 Pharyngeal fistula PT CTCAE_v5 ctcae5:C57350 Symptomatic (e.g., rectal discomfort, passing blood or mucus); medical intervention indicated; limiting instrumental ADL Symptomatic (e.g., rectal discomfort, passing blood or mucus); medical intervention indicated; limiting instrumental ADL Grade 2 Proctitis Grade 2 Proctitis, CTCAE 10036774 C57350 Grade 2 Proctitis Grade 2 Proctitis Symptomatic (e.g., rectal discomfort, passing blood or mucus); medical intervention indicated; limiting instrumental ADL NCI Symptomatic (e.g., rectal discomfort, passing blood or mucus); medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Proctitis PT CTCAE_v5 Grade 2 Proctitis, CTCAE PT NCI ctcae5:C57352 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Rectal Fistula, CTCAE Grade 2 Rectal fistula 10038062 C57352 Grade 2 Rectal fistula Grade 2 Rectal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Rectal Fistula, CTCAE PT NCI Grade 2 Rectal fistula PT CTCAE_v5 ctcae5:C57356 Symptomatic; altered GI function; limiting instrumental ADL Symptomatic; altered GI function; limiting instrumental ADL Grade 2 Rectal Obstruction, CTCAE Grade 2 Rectal obstruction 10065707 C57356 Grade 2 Rectal obstruction Grade 2 Rectal obstruction Symptomatic; altered GI function; limiting instrumental ADL NCI Symptomatic; altered GI function; limiting instrumental ADL CTCAE_v5 Grade 2 Rectal Obstruction, CTCAE PT NCI Grade 2 Rectal obstruction PT CTCAE_v5 ctcae5:C57357 Invasive intervention not indicated Invasive intervention not indicated Grade 2 Rectal Perforation, CTCAE Grade 2 Rectal perforation 10038073 C57357 Grade 2 Rectal perforation Grade 2 Rectal perforation Invasive intervention not indicated NCI Invasive intervention not indicated CTCAE_v5 Grade 2 Rectal Perforation, CTCAE PT NCI Grade 2 Rectal perforation PT CTCAE_v5 ctcae5:C57359 Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea) Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea) Grade 2 Rectal Ulcer, CTCAE Grade 2 Rectal ulcer 10038080 C57359 Grade 2 Rectal ulcer Grade 2 Rectal ulcer Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea) NCI Symptomatic; altered GI function (e.g., altered dietary habits, vomiting, diarrhea) CTCAE_v5 Grade 2 Rectal Ulcer, CTCAE PT NCI Grade 2 Rectal ulcer PT CTCAE_v5 ctcae5:C57360 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Salivary Gland Fistula, CTCAE Grade 2 Salivary gland fistula 10039411 C57360 Grade 2 Salivary gland fistula Grade 2 Salivary gland fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Salivary Gland Fistula, CTCAE PT NCI Grade 2 Salivary gland fistula PT CTCAE_v5 ctcae5:C57386 Outpatient IV hydration; medical intervention indicated Outpatient IV hydration; medical intervention indicated Grade 2 Vomiting Grade 2 Vomiting, CTCAE 10047700 C57386 Grade 2 Vomiting Grade 2 Vomiting Outpatient IV hydration; medical intervention indicated NCI Outpatient IV hydration; medical intervention indicated CTCAE_v5 Grade 2 Vomiting PT CTCAE_v5 Grade 2 Vomiting, CTCAE PT NCI ctcae5:C57391 Associated with significant weight loss or malnutrition (e.g., inadequate oral caloric and/or fluid intake); tube feeding or TPN indicated Associated with significant weight loss or malnutrition (e.g., inadequate oral caloric and/or fluid intake); tube feeding or TPN indicated Grade 3 Anorexia Grade 3 Anorexia, CTCAE 10002646 C57391 Grade 3 Anorexia Grade 3 Anorexia Associated with significant weight loss or malnutrition (e.g., inadequate oral caloric and/or fluid intake); tube feeding or TPN indicated NCI Associated with significant weight loss or malnutrition (e.g., inadequate oral caloric and/or fluid intake); tube feeding or TPN indicated CTCAE_v5 Grade 3 Anorexia PT CTCAE_v5 Grade 3 Anorexia, CTCAE PT NCI ctcae5:C57409 Severe abdominal pain; peritoneal signs Severe abdominal pain; peritoneal signs Grade 3 Colitis Grade 3 Colitis, CTCAE 10009887 C57409 Grade 3 Colitis Grade 3 Colitis Severe abdominal pain; peritoneal signs NCI Severe abdominal pain; peritoneal signs CTCAE_v5 Grade 3 Colitis PT CTCAE_v5 Grade 3 Colitis, CTCAE PT NCI ctcae5:C57416 Obstipation with manual evacuation indicated; limiting self care ADL Obstipation with manual evacuation indicated; limiting self care ADL Grade 3 Constipation Grade 3 Constipation, CTCAE 10010774 C57416 Grade 3 Constipation Grade 3 Constipation Obstipation with manual evacuation indicated; limiting self care ADL NCI Obstipation with manual evacuation indicated; limiting self care ADL CTCAE_v5 Grade 3 Constipation PT CTCAE_v5 Grade 3 Constipation, CTCAE PT NCI ctcae5:C57417 Hospitalization indicated Hospitalization indicated Grade 3 Dehydration Grade 3 Dehydration, CTCAE 10012174 C57417 Grade 3 Dehydration Grade 3 Dehydration Hospitalization indicated NCI Hospitalization indicated CTCAE_v5 Grade 3 Dehydration PT CTCAE_v5 Grade 3 Dehydration, CTCAE PT NCI ctcae5:C57418 Increase of >=7 stools per day over baseline; hospitalization indicated; severe increase in ostomy output compared to baseline; limiting self care ADL Increase of >=7 stools per day over baseline; hospitalization indicated; severe increase in ostomy output compared to baseline; limiting self care ADL Grade 3 Diarrhea Grade 3 Diarrhea, CTCAE 10012727 C57418 Grade 3 Diarrhea Grade 3 Diarrhea Increase of >=7 stools per day over baseline; hospitalization indicated; severe increase in ostomy output compared to baseline; limiting self care ADL NCI Increase of >=7 stools per day over baseline; hospitalization indicated; severe increase in ostomy output compared to baseline; limiting self care ADL CTCAE_v5 Grade 3 Diarrhea PT CTCAE_v5 Grade 3 Diarrhea, CTCAE PT NCI ctcae5:C57419 Invasive intervention indicated Invasive intervention indicated Grade 3 Duodenal Fistula, CTCAE Grade 3 Duodenal fistula 10013828 C57419 Grade 3 Duodenal fistula Grade 3 Duodenal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Duodenal Fistula, CTCAE PT NCI Grade 3 Duodenal fistula PT CTCAE_v5 ctcae5:C57425 Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated Grade 3 Dysphagia Grade 3 Dysphagia, CTCAE 10013950 C57425 Grade 3 Dysphagia Grade 3 Dysphagia Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated NCI Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated CTCAE_v5 Grade 3 Dysphagia PT CTCAE_v5 Grade 3 Dysphagia, CTCAE PT NCI ctcae5:C57427 Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated Grade 3 Esophagitis Grade 3 Esophagitis, CTCAE 10015461 C57427 Grade 3 Esophagitis Grade 3 Esophagitis Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated NCI Severely altered eating/swallowing; tube feeding, TPN, or hospitalization indicated CTCAE_v5 Grade 3 Esophagitis PT CTCAE_v5 Grade 3 Esophagitis, CTCAE PT NCI ctcae5:C57428 Invasive intervention indicated Invasive intervention indicated Grade 3 Esophageal Fistula, CTCAE Grade 3 Esophageal fistula 10065851 C57428 Grade 3 Esophageal fistula Grade 3 Esophageal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Esophageal Fistula, CTCAE PT NCI Grade 3 Esophageal fistula PT CTCAE_v5 ctcae5:C57437 Invasive intervention indicated Invasive intervention indicated Grade 3 Gallbladder Fistula, CTCAE Grade 3 Gallbladder fistula 10017631 C57437 Grade 3 Gallbladder fistula Grade 3 Gallbladder fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Gallbladder Fistula, CTCAE PT NCI Grade 3 Gallbladder fistula PT CTCAE_v5 ctcae5:C57439 Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated Grade 3 Gallbladder Obstruction, CTCAE Grade 3 Gallbladder obstruction 10017636 C57439 Grade 3 Gallbladder obstruction Grade 3 Gallbladder obstruction Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated NCI Symptomatic and severely altered GI function; tube feeding, TPN or hospitalization indicated; non-emergent operative intervention indicated CTCAE_v5 Grade 3 Gallbladder Obstruction, CTCAE PT NCI Grade 3 Gallbladder obstruction PT CTCAE_v5 ctcae5:C57441 Severely altered eating or gastric function; TPN or hospitalization indicated Severely altered eating or gastric function; TPN or hospitalization indicated Grade 3 Gastritis Grade 3 Gastritis, CTCAE 10017853 C57441 Grade 3 Gastritis Grade 3 Gastritis Severely altered eating or gastric function; TPN or hospitalization indicated NCI Severely altered eating or gastric function; TPN or hospitalization indicated CTCAE_v5 Grade 3 Gastritis PT CTCAE_v5 Grade 3 Gastritis, CTCAE PT NCI ctcae5:C57446 Severe symptoms; invasive intervention indicated Severe symptoms; invasive intervention indicated Grade 3 Hemorrhoids Grade 3 Hemorrhoids, CTCAE 10019611 C57446 Grade 3 Hemorrhoids Grade 3 Hemorrhoids Severe symptoms; invasive intervention indicated NCI Severe symptoms; invasive intervention indicated CTCAE_v5 Grade 3 Hemorrhoids PT CTCAE_v5 Grade 3 Hemorrhoids, CTCAE PT NCI ctcae5:C57448 Invasive intervention indicated Invasive intervention indicated Grade 3 Ileal Fistula, CTCAE Grade 3 Ileal fistula 10065728 C57448 Grade 3 Ileal fistula Grade 3 Ileal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Ileal Fistula, CTCAE PT NCI Grade 3 Ileal fistula PT CTCAE_v5 ctcae5:C57450 Hospitalization indicated; invasive intervention indicated; limiting self care ADL; long intestinal tube indicated Hospitalization indicated; invasive intervention indicated; limiting self care ADL; long intestinal tube indicated Grade 3 Ileal Obstruction, CTCAE Grade 3 Ileal obstruction 10065730 C57450 Grade 3 Ileal obstruction Grade 3 Ileal obstruction Hospitalization indicated; invasive intervention indicated; limiting self care ADL; long intestinal tube indicated NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL; long intestinal tube indicated CTCAE_v5 Grade 3 Ileal Obstruction, CTCAE PT NCI Grade 3 Ileal obstruction PT CTCAE_v5 ctcae5:C57453 Severely altered GI function; TPN indicated; elective invasive intervention indicated Severely altered GI function; TPN indicated; elective invasive intervention indicated Grade 3 Ileal Ulcer, CTCAE Grade 3 Ileal ulcer 10021309 C57453 Grade 3 Ileal ulcer Grade 3 Ileal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Ileal Ulcer, CTCAE PT NCI Grade 3 Ileal ulcer PT CTCAE_v5 ctcae5:C57454 Severely altered GI function; TPN indicated; tube placement indicated Severely altered GI function; TPN indicated; tube placement indicated Grade 3 Ileus Grade 3 Ileus, CTCAE 10021328 C57454 Grade 3 Ileus Grade 3 Ileus Severely altered GI function; TPN indicated; tube placement indicated NCI Severely altered GI function; TPN indicated; tube placement indicated CTCAE_v5 Grade 3 Ileus PT CTCAE_v5 Grade 3 Ileus, CTCAE PT NCI ctcae5:C57455 Invasive intervention indicated Invasive intervention indicated Grade 3 Jejunal Fistula, CTCAE Grade 3 Jejunal fistula 10065719 C57455 Grade 3 Jejunal fistula Grade 3 Jejunal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Jejunal Fistula, CTCAE PT NCI Grade 3 Jejunal fistula PT CTCAE_v5 ctcae5:C57457 Hospitalization indicated; invasive intervention indicated; limiting self care ADL Hospitalization indicated; invasive intervention indicated; limiting self care ADL Grade 3 Jejunal Obstruction, CTCAE Grade 3 Jejunal obstruction 10065732 C57457 Grade 3 Jejunal obstruction Grade 3 Jejunal obstruction Hospitalization indicated; invasive intervention indicated; limiting self care ADL NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Jejunal Obstruction, CTCAE PT NCI Grade 3 Jejunal obstruction PT CTCAE_v5 ctcae5:C57460 Severely altered GI function; TPN indicated; elective invasive intervention indicated Severely altered GI function; TPN indicated; elective invasive intervention indicated Grade 3 Jejunal Ulcer, CTCAE Grade 3 Jejunal ulcer 10023177 C57460 Grade 3 Jejunal ulcer Grade 3 Jejunal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Jejunal Ulcer, CTCAE PT NCI Grade 3 Jejunal ulcer PT CTCAE_v5 ctcae5:C57466 Inability to aliment adequately; TPN indicated Inability to aliment adequately; TPN indicated Grade 3 Malabsorption Grade 3 Malabsorption, CTCAE 10025476 C57466 Grade 3 Malabsorption Grade 3 Malabsorption Inability to aliment adequately; TPN indicated NCI Inability to aliment adequately; TPN indicated CTCAE_v5 Grade 3 Malabsorption PT CTCAE_v5 Grade 3 Malabsorption, CTCAE PT NCI ctcae5:C57467 Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated Grade 3 Nausea Grade 3 Nausea, CTCAE 10028813 C57467 Grade 3 Nausea Grade 3 Nausea Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated NCI Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated CTCAE_v5 Grade 3 Nausea PT CTCAE_v5 Grade 3 Nausea, CTCAE PT NCI ctcae5:C57473 Invasive intervention indicated Invasive intervention indicated Grade 3 Pancreatic Fistula, CTCAE Grade 3 Pancreatic fistula 10049192 C57473 Grade 3 Pancreatic fistula Grade 3 Pancreatic fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Pancreatic Fistula, CTCAE PT NCI Grade 3 Pancreatic fistula PT CTCAE_v5 ctcae5:C57477 Spontaneous bleeding; severe bone loss with or without tooth loss; osteonecrosis of maxilla or mandible Spontaneous bleeding; severe bone loss with or without tooth loss; osteonecrosis of maxilla or mandible Grade 3 Periodontal Disease, CTCAE Grade 3 Periodontal disease 10034536 C57477 Grade 3 Periodontal disease Grade 3 Periodontal disease Spontaneous bleeding; severe bone loss with or without tooth loss; osteonecrosis of maxilla or mandible NCI Spontaneous bleeding; severe bone loss with or without tooth loss; osteonecrosis of maxilla or mandible CTCAE_v5 Grade 3 Periodontal Disease, CTCAE PT NCI Grade 3 Periodontal disease PT CTCAE_v5 ctcae5:C57478 Tube feeding or TPN indicated; invasive intervention indicated Tube feeding or TPN indicated; invasive intervention indicated Grade 3 Peritoneal Necrosis, CTCAE Grade 3 Peritoneal necrosis 10065704 C57478 Grade 3 Peritoneal necrosis Grade 3 Peritoneal necrosis Tube feeding or TPN indicated; invasive intervention indicated NCI Tube feeding or TPN indicated; invasive intervention indicated CTCAE_v5 Grade 3 Peritoneal Necrosis, CTCAE PT NCI Grade 3 Peritoneal necrosis PT CTCAE_v5 ctcae5:C57479 Invasive intervention indicated Invasive intervention indicated Grade 3 Pharyngeal Fistula, CTCAE Grade 3 Pharyngeal fistula 10034825 C57479 Grade 3 Pharyngeal fistula Grade 3 Pharyngeal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Pharyngeal Fistula, CTCAE PT NCI Grade 3 Pharyngeal fistula PT CTCAE_v5 ctcae5:C57483 Inability to aliment adequately by GI tract; invasive intervention indicated; tube feeding or TPN indicated Inability to aliment adequately by GI tract; invasive intervention indicated; tube feeding or TPN indicated Grade 3 Pharyngeal Necrosis, CTCAE Grade 3 Pharyngeal necrosis 10065706 C57483 Grade 3 Pharyngeal necrosis Grade 3 Pharyngeal necrosis Inability to aliment adequately by GI tract; invasive intervention indicated; tube feeding or TPN indicated NCI Inability to aliment adequately by GI tract; invasive intervention indicated; tube feeding or TPN indicated CTCAE_v5 Grade 3 Pharyngeal Necrosis, CTCAE PT NCI Grade 3 Pharyngeal necrosis PT CTCAE_v5 ctcae5:C57485 Severe symptoms; fecal urgency or stool incontinence; limiting self care ADL Severe symptoms; fecal urgency or stool incontinence; limiting self care ADL Grade 3 Proctitis Grade 3 Proctitis, CTCAE 10036774 C57485 Grade 3 Proctitis Grade 3 Proctitis Severe symptoms; fecal urgency or stool incontinence; limiting self care ADL NCI Severe symptoms; fecal urgency or stool incontinence; limiting self care ADL CTCAE_v5 Grade 3 Proctitis PT CTCAE_v5 Grade 3 Proctitis, CTCAE PT NCI ctcae5:C57487 Invasive intervention indicated Invasive intervention indicated Grade 3 Rectal Fistula, CTCAE Grade 3 Rectal fistula 10038062 C57487 Grade 3 Rectal fistula Grade 3 Rectal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Rectal Fistula, CTCAE PT NCI Grade 3 Rectal fistula PT CTCAE_v5 ctcae5:C57491 Tube feeding or TPN indicated; invasive intervention indicated Tube feeding or TPN indicated; invasive intervention indicated Grade 3 Rectal Necrosis, CTCAE Grade 3 Rectal necrosis 10065709 C57491 Grade 3 Rectal necrosis Grade 3 Rectal necrosis Tube feeding or TPN indicated; invasive intervention indicated NCI Tube feeding or TPN indicated; invasive intervention indicated CTCAE_v5 Grade 3 Rectal Necrosis, CTCAE PT NCI Grade 3 Rectal necrosis PT CTCAE_v5 ctcae5:C57492 Hospitalization indicated; invasive intervention indicated; limiting self care ADL Hospitalization indicated; invasive intervention indicated; limiting self care ADL Grade 3 Rectal Obstruction, CTCAE Grade 3 Rectal obstruction 10065707 C57492 Grade 3 Rectal obstruction Grade 3 Rectal obstruction Hospitalization indicated; invasive intervention indicated; limiting self care ADL NCI Hospitalization indicated; invasive intervention indicated; limiting self care ADL CTCAE_v5 Grade 3 Rectal Obstruction, CTCAE PT NCI Grade 3 Rectal obstruction PT CTCAE_v5 ctcae5:C57493 Invasive intervention indicated Invasive intervention indicated Grade 3 Rectal Perforation, CTCAE Grade 3 Rectal perforation 10038073 C57493 Grade 3 Rectal perforation Grade 3 Rectal perforation Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Rectal Perforation, CTCAE PT NCI Grade 3 Rectal perforation PT CTCAE_v5 ctcae5:C57495 Severely altered GI function; TPN indicated; elective invasive intervention indicated Severely altered GI function; TPN indicated; elective invasive intervention indicated Grade 3 Rectal Ulcer, CTCAE Grade 3 Rectal ulcer 10038080 C57495 Grade 3 Rectal ulcer Grade 3 Rectal ulcer Severely altered GI function; TPN indicated; elective invasive intervention indicated NCI Severely altered GI function; TPN indicated; elective invasive intervention indicated CTCAE_v5 Grade 3 Rectal Ulcer, CTCAE PT NCI Grade 3 Rectal ulcer PT CTCAE_v5 ctcae5:C57496 Invasive intervention indicated Invasive intervention indicated Grade 3 Salivary Gland Fistula, CTCAE Grade 3 Salivary gland fistula 10039411 C57496 Grade 3 Salivary gland fistula Grade 3 Salivary gland fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Salivary Gland Fistula, CTCAE PT NCI Grade 3 Salivary gland fistula PT CTCAE_v5 ctcae5:C57523 Symptomatic (e.g., abdominal pain, fever, change in bowel habits with ileus); peritoneal signs Symptomatic (e.g., abdominal pain, fever, change in bowel habits with ileus); peritoneal signs Grade 3 Typhlitis Grade 3 Typhlitis, CTCAE 10045271 C57523 Grade 3 Typhlitis Grade 3 Typhlitis Symptomatic (e.g., abdominal pain, fever, change in bowel habits with ileus); peritoneal signs NCI Symptomatic (e.g., abdominal pain, fever, change in bowel habits with ileus); peritoneal signs CTCAE_v5 Grade 3 Typhlitis PT CTCAE_v5 Grade 3 Typhlitis, CTCAE PT NCI ctcae5:C57524 Tube feeding, TPN, or hospitalization indicated Tube feeding, TPN, or hospitalization indicated Grade 3 Vomiting Grade 3 Vomiting, CTCAE 10047700 C57524 Grade 3 Vomiting Grade 3 Vomiting Tube feeding, TPN, or hospitalization indicated NCI Tube feeding, TPN, or hospitalization indicated CTCAE_v5 Grade 3 Vomiting PT CTCAE_v5 Grade 3 Vomiting, CTCAE PT NCI ctcae5:C57528 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Anorexia Grade 4 Anorexia, CTCAE 10002646 C57528 Grade 4 Anorexia Grade 4 Anorexia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Anorexia PT CTCAE_v5 Grade 4 Anorexia, CTCAE PT NCI ctcae5:C57544 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Colitis Grade 4 Colitis, CTCAE 10009887 C57544 Grade 4 Colitis Grade 4 Colitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Colitis PT CTCAE_v5 Grade 4 Colitis, CTCAE PT NCI ctcae5:C57551 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Constipation Grade 4 Constipation, CTCAE 10010774 C57551 Grade 4 Constipation Grade 4 Constipation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Constipation PT CTCAE_v5 Grade 4 Constipation, CTCAE PT NCI ctcae5:C57552 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Dehydration Grade 4 Dehydration, CTCAE 10012174 C57552 Grade 4 Dehydration Grade 4 Dehydration Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Dehydration PT CTCAE_v5 Grade 4 Dehydration, CTCAE PT NCI ctcae5:C57553 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Diarrhea Grade 4 Diarrhea, CTCAE 10012727 C57553 Grade 4 Diarrhea Grade 4 Diarrhea Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Diarrhea PT CTCAE_v5 Grade 4 Diarrhea, CTCAE PT NCI ctcae5:C57554 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Duodenal Fistula, CTCAE Grade 4 Duodenal fistula 10013828 C57554 Grade 4 Duodenal fistula Grade 4 Duodenal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Duodenal Fistula, CTCAE PT NCI Grade 4 Duodenal fistula PT CTCAE_v5 ctcae5:C57560 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Dysphagia Grade 4 Dysphagia, CTCAE 10013950 C57560 Grade 4 Dysphagia Grade 4 Dysphagia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Dysphagia PT CTCAE_v5 Grade 4 Dysphagia, CTCAE PT NCI ctcae5:C57562 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Esophagitis Grade 4 Esophagitis, CTCAE 10015461 C57562 Grade 4 Esophagitis Grade 4 Esophagitis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Esophagitis PT CTCAE_v5 Grade 4 Esophagitis, CTCAE PT NCI ctcae5:C57563 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Esophageal Fistula, CTCAE Grade 4 Esophageal fistula 10065851 C57563 Grade 4 Esophageal fistula Grade 4 Esophageal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Esophageal Fistula, CTCAE PT NCI Grade 4 Esophageal fistula PT CTCAE_v5 ctcae5:C57572 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gallbladder Fistula, CTCAE Grade 4 Gallbladder fistula 10017631 C57572 Grade 4 Gallbladder fistula Grade 4 Gallbladder fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gallbladder Fistula, CTCAE PT NCI Grade 4 Gallbladder fistula PT CTCAE_v5 ctcae5:C57573 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Gallbladder Necrosis, CTCAE Grade 4 Gallbladder necrosis 10059446 C57573 Grade 4 Gallbladder necrosis Grade 4 Gallbladder necrosis Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Gallbladder Necrosis, CTCAE PT NCI Grade 4 Gallbladder necrosis PT CTCAE_v5 ctcae5:C57574 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gallbladder Obstruction, CTCAE Grade 4 Gallbladder obstruction 10017636 C57574 Grade 4 Gallbladder obstruction Grade 4 Gallbladder obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gallbladder Obstruction, CTCAE PT NCI Grade 4 Gallbladder obstruction PT CTCAE_v5 ctcae5:C57575 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Gallbladder Perforation, CTCAE Grade 4 Gallbladder perforation 10017639 C57575 Grade 4 Gallbladder perforation Grade 4 Gallbladder perforation Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Gallbladder Perforation, CTCAE PT NCI Grade 4 Gallbladder perforation PT CTCAE_v5 ctcae5:C57576 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Gastritis Grade 4 Gastritis, CTCAE 10017853 C57576 Grade 4 Gastritis Grade 4 Gastritis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Gastritis PT CTCAE_v5 Grade 4 Gastritis, CTCAE PT NCI ctcae5:C57581 Life-threatening consequences; urgent invasive intervention indicated Life-threatening consequences; urgent invasive intervention indicated Grade 4 Hepatic Necrosis, CTCAE Grade 4 Hepatic necrosis 10019692 C57581 Grade 4 Hepatic necrosis Grade 4 Hepatic necrosis Life-threatening consequences; urgent invasive intervention indicated NCI Life-threatening consequences; urgent invasive intervention indicated CTCAE_v5 Grade 4 Hepatic Necrosis, CTCAE PT NCI Grade 4 Hepatic necrosis PT CTCAE_v5 ctcae5:C57582 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ileal Fistula, CTCAE Grade 4 Ileal fistula 10065728 C57582 Grade 4 Ileal fistula Grade 4 Ileal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ileal Fistula, CTCAE PT NCI Grade 4 Ileal fistula PT CTCAE_v5 ctcae5:C57584 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ileal Obstruction, CTCAE Grade 4 Ileal obstruction 10065730 C57584 Grade 4 Ileal obstruction Grade 4 Ileal obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ileal Obstruction, CTCAE PT NCI Grade 4 Ileal obstruction PT CTCAE_v5 ctcae5:C57587 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Ileal Ulcer, CTCAE Grade 4 Ileal ulcer 10021309 C57587 Grade 4 Ileal ulcer Grade 4 Ileal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Ileal Ulcer, CTCAE PT NCI Grade 4 Ileal ulcer PT CTCAE_v5 ctcae5:C57588 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Ileus Grade 4 Ileus, CTCAE 10021328 C57588 Grade 4 Ileus Grade 4 Ileus Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Ileus PT CTCAE_v5 Grade 4 Ileus, CTCAE PT NCI ctcae5:C57589 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Jejunal Fistula, CTCAE Grade 4 Jejunal fistula 10065719 C57589 Grade 4 Jejunal fistula Grade 4 Jejunal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Jejunal Fistula, CTCAE PT NCI Grade 4 Jejunal fistula PT CTCAE_v5 ctcae5:C57591 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Jejunal Obstruction, CTCAE Grade 4 Jejunal obstruction 10065732 C57591 Grade 4 Jejunal obstruction Grade 4 Jejunal obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Jejunal Obstruction, CTCAE PT NCI Grade 4 Jejunal obstruction PT CTCAE_v5 ctcae5:C57594 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Jejunal Ulcer, CTCAE Grade 4 Jejunal ulcer 10023177 C57594 Grade 4 Jejunal ulcer Grade 4 Jejunal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Jejunal Ulcer, CTCAE PT NCI Grade 4 Jejunal ulcer PT CTCAE_v5 ctcae5:C57600 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Malabsorption Grade 4 Malabsorption, CTCAE 10025476 C57600 Grade 4 Malabsorption Grade 4 Malabsorption Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Malabsorption PT CTCAE_v5 Grade 4 Malabsorption, CTCAE PT NCI ctcae5:C57607 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pancreatic Fistula, CTCAE Grade 4 Pancreatic fistula 10049192 C57607 Grade 4 Pancreatic fistula Grade 4 Pancreatic fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pancreatic Fistula, CTCAE PT NCI Grade 4 Pancreatic fistula PT CTCAE_v5 ctcae5:C57611 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Peritoneal Necrosis, CTCAE Grade 4 Peritoneal necrosis 10065704 C57611 Grade 4 Peritoneal necrosis Grade 4 Peritoneal necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Peritoneal Necrosis, CTCAE PT NCI Grade 4 Peritoneal necrosis PT CTCAE_v5 ctcae5:C57612 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pharyngeal Fistula, CTCAE Grade 4 Pharyngeal fistula 10034825 C57612 Grade 4 Pharyngeal fistula Grade 4 Pharyngeal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pharyngeal Fistula, CTCAE PT NCI Grade 4 Pharyngeal fistula PT CTCAE_v5 ctcae5:C57616 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Pharyngeal Necrosis, CTCAE Grade 4 Pharyngeal necrosis 10065706 C57616 Grade 4 Pharyngeal necrosis Grade 4 Pharyngeal necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Pharyngeal Necrosis, CTCAE PT NCI Grade 4 Pharyngeal necrosis PT CTCAE_v5 ctcae5:C57618 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Proctitis Grade 4 Proctitis, CTCAE 10036774 C57618 Grade 4 Proctitis Grade 4 Proctitis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Proctitis PT CTCAE_v5 Grade 4 Proctitis, CTCAE PT NCI ctcae5:C57620 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Rectal Fistula, CTCAE Grade 4 Rectal fistula 10038062 C57620 Grade 4 Rectal fistula Grade 4 Rectal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Rectal Fistula, CTCAE PT NCI Grade 4 Rectal fistula PT CTCAE_v5 ctcae5:C57624 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Necrosis, CTCAE Grade 4 Rectal necrosis 10065709 C57624 Grade 4 Rectal necrosis Grade 4 Rectal necrosis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Necrosis, CTCAE PT NCI Grade 4 Rectal necrosis PT CTCAE_v5 ctcae5:C57625 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Obstruction, CTCAE Grade 4 Rectal obstruction 10065707 C57625 Grade 4 Rectal obstruction Grade 4 Rectal obstruction Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Obstruction, CTCAE PT NCI Grade 4 Rectal obstruction PT CTCAE_v5 ctcae5:C57626 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Perforation, CTCAE Grade 4 Rectal perforation 10038073 C57626 Grade 4 Rectal perforation Grade 4 Rectal perforation Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Perforation, CTCAE PT NCI Grade 4 Rectal perforation PT CTCAE_v5 ctcae5:C57628 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Rectal Ulcer, CTCAE Grade 4 Rectal ulcer 10038080 C57628 Grade 4 Rectal ulcer Grade 4 Rectal ulcer Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Rectal Ulcer, CTCAE PT NCI Grade 4 Rectal ulcer PT CTCAE_v5 ctcae5:C57629 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Salivary Gland Fistula, CTCAE Grade 4 Salivary gland fistula 10039411 C57629 Grade 4 Salivary gland fistula Grade 4 Salivary gland fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Salivary Gland Fistula, CTCAE PT NCI Grade 4 Salivary gland fistula PT CTCAE_v5 ctcae5:C57655 Life-threatening consequences; urgent operative intervention indicated Life-threatening consequences; urgent operative intervention indicated Grade 4 Typhlitis Grade 4 Typhlitis, CTCAE 10045271 C57655 Grade 4 Typhlitis Grade 4 Typhlitis Life-threatening consequences; urgent operative intervention indicated NCI Life-threatening consequences; urgent operative intervention indicated CTCAE_v5 Grade 4 Typhlitis PT CTCAE_v5 Grade 4 Typhlitis, CTCAE PT NCI ctcae5:C57656 Life-threatening consequences Life-threatening consequences Grade 4 Vomiting Grade 4 Vomiting, CTCAE 10047700 C57656 Grade 4 Vomiting Grade 4 Vomiting Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Vomiting PT CTCAE_v5 Grade 4 Vomiting, CTCAE PT NCI ctcae5:C57659 Death Death Grade 5 Anorexia Grade 5 Anorexia, CTCAE 10002646 C57659 Grade 5 Anorexia Grade 5 Anorexia Death NCI Death CTCAE_v5 Grade 5 Anorexia PT CTCAE_v5 Grade 5 Anorexia, CTCAE PT NCI ctcae5:C57675 Death Death Grade 5 Colitis Grade 5 Colitis, CTCAE 10009887 C57675 Grade 5 Colitis Grade 5 Colitis Death NCI Death CTCAE_v5 Grade 5 Colitis PT CTCAE_v5 Grade 5 Colitis, CTCAE PT NCI ctcae5:C57682 Death Death Grade 5 Constipation Grade 5 Constipation, CTCAE 10010774 C57682 Grade 5 Constipation Grade 5 Constipation Death NCI Death CTCAE_v5 Grade 5 Constipation PT CTCAE_v5 Grade 5 Constipation, CTCAE PT NCI ctcae5:C57683 Death Death Grade 5 Dehydration Grade 5 Dehydration, CTCAE 10012174 C57683 Grade 5 Dehydration Grade 5 Dehydration Death NCI Death CTCAE_v5 Grade 5 Dehydration PT CTCAE_v5 Grade 5 Dehydration, CTCAE PT NCI ctcae5:C57684 Death Death Grade 5 Diarrhea Grade 5 Diarrhea, CTCAE 10012727 C57684 Grade 5 Diarrhea Grade 5 Diarrhea Death NCI Death CTCAE_v5 Grade 5 Diarrhea PT CTCAE_v5 Grade 5 Diarrhea, CTCAE PT NCI ctcae5:C57685 Death Death Grade 5 Duodenal Fistula, CTCAE Grade 5 Duodenal fistula 10013828 C57685 Grade 5 Duodenal fistula Grade 5 Duodenal fistula Death NCI Death CTCAE_v5 Grade 5 Duodenal Fistula, CTCAE PT NCI Grade 5 Duodenal fistula PT CTCAE_v5 ctcae5:C57691 Death Death Grade 5 Dysphagia Grade 5 Dysphagia, CTCAE 10013950 C57691 Grade 5 Dysphagia Grade 5 Dysphagia Death NCI Death CTCAE_v5 Grade 5 Dysphagia PT CTCAE_v5 Grade 5 Dysphagia, CTCAE PT NCI ctcae5:C57693 Death Death Grade 5 Esophagitis Grade 5 Esophagitis, CTCAE 10015461 C57693 Grade 5 Esophagitis Grade 5 Esophagitis Death NCI Death CTCAE_v5 Grade 5 Esophagitis PT CTCAE_v5 Grade 5 Esophagitis, CTCAE PT NCI ctcae5:C57694 Death Death Grade 5 Esophageal Fistula, CTCAE Grade 5 Esophageal fistula 10065851 C57694 Grade 5 Esophageal fistula Grade 5 Esophageal fistula Death NCI Death CTCAE_v5 Grade 5 Esophageal Fistula, CTCAE PT NCI Grade 5 Esophageal fistula PT CTCAE_v5 ctcae5:C57703 Death Death Grade 5 Gallbladder Fistula, CTCAE Grade 5 Gallbladder fistula 10017631 C57703 Grade 5 Gallbladder fistula Grade 5 Gallbladder fistula Death NCI Death CTCAE_v5 Grade 5 Gallbladder Fistula, CTCAE PT NCI Grade 5 Gallbladder fistula PT CTCAE_v5 ctcae5:C57704 Death Death Grade 5 Gallbladder Necrosis, CTCAE Grade 5 Gallbladder necrosis 10059446 C57704 Grade 5 Gallbladder necrosis Grade 5 Gallbladder necrosis Death NCI Death CTCAE_v5 Grade 5 Gallbladder Necrosis, CTCAE PT NCI Grade 5 Gallbladder necrosis PT CTCAE_v5 ctcae5:C57705 Death Death Grade 5 Gallbladder Obstruction, CTCAE Grade 5 Gallbladder obstruction 10017636 C57705 Grade 5 Gallbladder obstruction Grade 5 Gallbladder obstruction Death NCI Death CTCAE_v5 Grade 5 Gallbladder Obstruction, CTCAE PT NCI Grade 5 Gallbladder obstruction PT CTCAE_v5 ctcae5:C57706 Death Death Grade 5 Gallbladder Perforation, CTCAE Grade 5 Gallbladder perforation 10017639 C57706 Grade 5 Gallbladder perforation Grade 5 Gallbladder perforation Death NCI Death CTCAE_v5 Grade 5 Gallbladder Perforation, CTCAE PT NCI Grade 5 Gallbladder perforation PT CTCAE_v5 ctcae5:C57707 Death Death Grade 5 Gastritis Grade 5 Gastritis, CTCAE 10017853 C57707 Grade 5 Gastritis Grade 5 Gastritis Death NCI Death CTCAE_v5 Grade 5 Gastritis PT CTCAE_v5 Grade 5 Gastritis, CTCAE PT NCI ctcae5:C57712 Death Death Grade 5 Hepatic Necrosis, CTCAE Grade 5 Hepatic necrosis 10019692 C57712 Grade 5 Hepatic necrosis Grade 5 Hepatic necrosis Death NCI Death CTCAE_v5 Grade 5 Hepatic Necrosis, CTCAE PT NCI Grade 5 Hepatic necrosis PT CTCAE_v5 ctcae5:C57713 Death Death Grade 5 Ileal Fistula, CTCAE Grade 5 Ileal fistula 10065728 C57713 Grade 5 Ileal fistula Grade 5 Ileal fistula Death NCI Death CTCAE_v5 Grade 5 Ileal Fistula, CTCAE PT NCI Grade 5 Ileal fistula PT CTCAE_v5 ctcae5:C57715 Death Death Grade 5 Ileal Obstruction, CTCAE Grade 5 Ileal obstruction 10065730 C57715 Grade 5 Ileal obstruction Grade 5 Ileal obstruction Death NCI Death CTCAE_v5 Grade 5 Ileal Obstruction, CTCAE PT NCI Grade 5 Ileal obstruction PT CTCAE_v5 ctcae5:C57718 Death Death Grade 5 Ileal Ulcer, CTCAE Grade 5 Ileal ulcer 10021309 C57718 Grade 5 Ileal ulcer Grade 5 Ileal ulcer Death NCI Death CTCAE_v5 Grade 5 Ileal Ulcer, CTCAE PT NCI Grade 5 Ileal ulcer PT CTCAE_v5 ctcae5:C57719 Death Death Grade 5 Ileus Grade 5 Ileus, CTCAE 10021328 C57719 Grade 5 Ileus Grade 5 Ileus Death NCI Death CTCAE_v5 Grade 5 Ileus PT CTCAE_v5 Grade 5 Ileus, CTCAE PT NCI ctcae5:C57720 Death Death Grade 5 Jejunal Fistula, CTCAE Grade 5 Jejunal fistula 10065719 C57720 Grade 5 Jejunal fistula Grade 5 Jejunal fistula Death NCI Death CTCAE_v5 Grade 5 Jejunal Fistula, CTCAE PT NCI Grade 5 Jejunal fistula PT CTCAE_v5 ctcae5:C57722 Death Death Grade 5 Jejunal Obstruction, CTCAE Grade 5 Jejunal obstruction 10065732 C57722 Grade 5 Jejunal obstruction Grade 5 Jejunal obstruction Death NCI Death CTCAE_v5 Grade 5 Jejunal Obstruction, CTCAE PT NCI Grade 5 Jejunal obstruction PT CTCAE_v5 ctcae5:C57725 Death Death Grade 5 Jejunal Ulcer, CTCAE Grade 5 Jejunal ulcer 10023177 C57725 Grade 5 Jejunal ulcer Grade 5 Jejunal ulcer Death NCI Death CTCAE_v5 Grade 5 Jejunal Ulcer, CTCAE PT NCI Grade 5 Jejunal ulcer PT CTCAE_v5 ctcae5:C57731 Death Death Grade 5 Malabsorption Grade 5 Malabsorption, CTCAE 10025476 C57731 Grade 5 Malabsorption Grade 5 Malabsorption Death NCI Death CTCAE_v5 Grade 5 Malabsorption PT CTCAE_v5 Grade 5 Malabsorption, CTCAE PT NCI ctcae5:C57738 Death Death Grade 5 Pancreatic Fistula, CTCAE Grade 5 Pancreatic fistula 10049192 C57738 Grade 5 Pancreatic fistula Grade 5 Pancreatic fistula Death NCI Death CTCAE_v5 Grade 5 Pancreatic Fistula, CTCAE PT NCI Grade 5 Pancreatic fistula PT CTCAE_v5 ctcae5:C57742 Death Death Grade 5 Peritoneal Necrosis, CTCAE Grade 5 Peritoneal necrosis 10065704 C57742 Grade 5 Peritoneal necrosis Grade 5 Peritoneal necrosis Death NCI Death CTCAE_v5 Grade 5 Peritoneal Necrosis, CTCAE PT NCI Grade 5 Peritoneal necrosis PT CTCAE_v5 ctcae5:C57743 Death Death Grade 5 Pharyngeal Fistula, CTCAE Grade 5 Pharyngeal fistula 10034825 C57743 Grade 5 Pharyngeal fistula Grade 5 Pharyngeal fistula Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Fistula, CTCAE PT NCI Grade 5 Pharyngeal fistula PT CTCAE_v5 ctcae5:C57747 Death Death Grade 5 Pharyngeal Necrosis, CTCAE Grade 5 Pharyngeal necrosis 10065706 C57747 Grade 5 Pharyngeal necrosis Grade 5 Pharyngeal necrosis Death NCI Death CTCAE_v5 Grade 5 Pharyngeal Necrosis, CTCAE PT NCI Grade 5 Pharyngeal necrosis PT CTCAE_v5 ctcae5:C57749 Death Death Grade 5 Proctitis Grade 5 Proctitis, CTCAE 10036774 C57749 Grade 5 Proctitis Grade 5 Proctitis Death NCI Death CTCAE_v5 Grade 5 Proctitis PT CTCAE_v5 Grade 5 Proctitis, CTCAE PT NCI ctcae5:C57751 Death Death Grade 5 Rectal Fistula, CTCAE Grade 5 Rectal fistula 10038062 C57751 Grade 5 Rectal fistula Grade 5 Rectal fistula Death NCI Death CTCAE_v5 Grade 5 Rectal Fistula, CTCAE PT NCI Grade 5 Rectal fistula PT CTCAE_v5 ctcae5:C57755 Death Death Grade 5 Rectal Necrosis, CTCAE Grade 5 Rectal necrosis 10065709 C57755 Grade 5 Rectal necrosis Grade 5 Rectal necrosis Death NCI Death CTCAE_v5 Grade 5 Rectal Necrosis, CTCAE PT NCI Grade 5 Rectal necrosis PT CTCAE_v5 ctcae5:C57756 Death Death Grade 5 Rectal Obstruction, CTCAE Grade 5 Rectal obstruction 10065707 C57756 Grade 5 Rectal obstruction Grade 5 Rectal obstruction Death NCI Death CTCAE_v5 Grade 5 Rectal Obstruction, CTCAE PT NCI Grade 5 Rectal obstruction PT CTCAE_v5 ctcae5:C57757 Death Death Grade 5 Rectal Perforation, CTCAE Grade 5 Rectal perforation 10038073 C57757 Grade 5 Rectal perforation Grade 5 Rectal perforation Death NCI Death CTCAE_v5 Grade 5 Rectal Perforation, CTCAE PT NCI Grade 5 Rectal perforation PT CTCAE_v5 ctcae5:C57759 Death Death Grade 5 Rectal Ulcer, CTCAE Grade 5 Rectal ulcer 10038080 C57759 Grade 5 Rectal ulcer Grade 5 Rectal ulcer Death NCI Death CTCAE_v5 Grade 5 Rectal Ulcer, CTCAE PT NCI Grade 5 Rectal ulcer PT CTCAE_v5 ctcae5:C57760 Death Death Grade 5 Salivary Gland Fistula, CTCAE Grade 5 Salivary gland fistula 10039411 C57760 Grade 5 Salivary gland fistula Grade 5 Salivary gland fistula Death NCI Death CTCAE_v5 Grade 5 Salivary Gland Fistula, CTCAE PT NCI Grade 5 Salivary gland fistula PT CTCAE_v5 ctcae5:C57785 Death Death Grade 5 Typhlitis Grade 5 Typhlitis, CTCAE 10045271 C57785 Grade 5 Typhlitis Grade 5 Typhlitis Death NCI Death CTCAE_v5 Grade 5 Typhlitis PT CTCAE_v5 Grade 5 Typhlitis, CTCAE PT NCI ctcae5:C57786 Death Death Grade 5 Vomiting Grade 5 Vomiting, CTCAE 10047700 C57786 Grade 5 Vomiting Grade 5 Vomiting Death NCI Death CTCAE_v5 Grade 5 Vomiting PT CTCAE_v5 Grade 5 Vomiting, CTCAE PT NCI ctcae5:C57787 A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. Dehydration Dehydration, CTCAE 10012174 C57787 Dehydration Dehydration A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. NCI A disorder characterized by excessive loss of water from the body. It is usually caused by severe diarrhea, vomiting or diaphoresis. CTCAE_v5 Dehydration PT CTCAE_v5 Dehydration, CTCAE PT NCI ctcae5:C57788 A disorder characterized by an increase in frequency and/or loose or watery bowel movements. A disorder characterized by an increase in frequency and/or loose or watery bowel movements. Diarrhea Diarrhea, CTCAE 10012727 C57788 Diarrhea Diarrhea A disorder characterized by an increase in frequency and/or loose or watery bowel movements. NCI A disorder characterized by an increase in frequency and/or loose or watery bowel movements. CTCAE_v5 Diarrhea PT CTCAE_v5 Diarrhea, CTCAE PT NCI ctcae5:C57789 A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. Duodenal Fistula, CTCAE Duodenal fistula 10013828 C57789 Duodenal fistula Duodenal fistula A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the duodenum and another organ or anatomic site. CTCAE_v5 Duodenal Fistula, CTCAE PT NCI Duodenal fistula PT CTCAE_v5 ctcae5:C57795 A disorder characterized by difficulty in swallowing. A disorder characterized by difficulty in swallowing. Dysphagia Dysphagia, CTCAE 10013950 C57795 Dysphagia Dysphagia A disorder characterized by difficulty in swallowing. NCI A disorder characterized by difficulty in swallowing. CTCAE_v5 Dysphagia PT CTCAE_v5 Dysphagia, CTCAE PT NCI ctcae5:C57797 A disorder characterized by inflammation of the esophageal wall. A disorder characterized by inflammation of the esophageal wall. Esophagitis Esophagitis, CTCAE 10015461 C57797 Esophagitis Esophagitis A disorder characterized by inflammation of the esophageal wall. NCI A disorder characterized by inflammation of the esophageal wall. CTCAE_v5 Esophagitis PT CTCAE_v5 Esophagitis, CTCAE PT NCI ctcae5:C57798 A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. Esophageal Fistula, CTCAE Esophageal fistula 10065851 C57798 Esophageal fistula Esophageal fistula A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the esophagus and another organ or anatomic site. CTCAE_v5 Esophageal Fistula, CTCAE PT NCI Esophageal fistula PT CTCAE_v5 ctcae5:C57807 A disorder characterized by a discharge of excessive gas from the lower GI tract. A disorder characterized by a discharge of excessive gas from the lower GI tract. Flatulence Flatulence, CTCAE 10016766 C57807 Flatulence Flatulence A disorder characterized by a discharge of excessive gas from the lower GI tract. NCI A disorder characterized by a discharge of excessive gas from the lower GI tract. CTCAE_v5 Flatulence PT CTCAE_v5 Flatulence, CTCAE PT NCI ctcae5:C57808 A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. Gallbladder Fistula, CTCAE Gallbladder fistula 10017631 C57808 Gallbladder fistula Gallbladder fistula A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the gallbladder and another organ or anatomic site. CTCAE_v5 Gallbladder Fistula, CTCAE PT NCI Gallbladder fistula PT CTCAE_v5 ctcae5:C57810 A disorder characterized by blockage of the normal flow of the contents of the gallbladder. A disorder characterized by blockage of the normal flow of the contents of the gallbladder. Gallbladder Obstruction, CTCAE Gallbladder obstruction 10017636 C57810 Gallbladder obstruction Gallbladder obstruction A disorder characterized by blockage of the normal flow of the contents of the gallbladder. NCI A disorder characterized by blockage of the normal flow of the contents of the gallbladder. CTCAE_v5 Gallbladder Obstruction, CTCAE PT NCI Gallbladder obstruction PT CTCAE_v5 ctcae5:C57812 A disorder characterized by inflammation of the stomach. A disorder characterized by inflammation of the stomach. Gastritis Gastritis, CTCAE 10017853 C57812 Gastritis Gastritis A disorder characterized by inflammation of the stomach. NCI A disorder characterized by inflammation of the stomach. CTCAE_v5 Gastritis PT CTCAE_v5 Gastritis, CTCAE PT NCI ctcae5:C57814 A disorder characterized by failure of the ileum to transport intestinal contents. A disorder characterized by failure of the ileum to transport intestinal contents. Ileus Ileus, CTCAE 10021328 C57814 Ileus Ileus A disorder characterized by failure of the ileum to transport intestinal contents. NCI A disorder characterized by failure of the ileum to transport intestinal contents. CTCAE_v5 Ileus PT CTCAE_v5 Ileus, CTCAE PT NCI ctcae5:C57821 A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. Ileal Fistula, CTCAE Ileal fistula 10065728 C57821 Ileal fistula Ileal fistula A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the ileum and another organ or anatomic site. CTCAE_v5 Ileal Fistula, CTCAE PT NCI Ileal fistula PT CTCAE_v5 ctcae5:C57823 A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. Ileal Obstruction, CTCAE Ileal obstruction 10065730 C57823 Ileal obstruction Ileal obstruction A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. NCI A disorder characterized by blockage of the normal flow of the intestinal contents in the ileum. CTCAE_v5 Ileal Obstruction, CTCAE PT NCI Ileal obstruction PT CTCAE_v5 ctcae5:C57826 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the ileum. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the ileum. Ileal Ulcer, CTCAE Ileal ulcer 10021309 C57826 Ileal ulcer Ileal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the ileum. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the ileum. CTCAE_v5 Ileal Ulcer, CTCAE PT NCI Ileal ulcer PT CTCAE_v5 ctcae5:C57827 A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. Jejunal Fistula, CTCAE Jejunal fistula 10065719 C57827 Jejunal fistula Jejunal fistula A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the jejunum and another organ or anatomic site. CTCAE_v5 Jejunal Fistula, CTCAE PT NCI Jejunal fistula PT CTCAE_v5 ctcae5:C57829 A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. Jejunal Obstruction, CTCAE Jejunal obstruction 10065732 C57829 Jejunal obstruction Jejunal obstruction A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. NCI A disorder characterized by blockage of the normal flow of the intestinal contents in the jejunum. CTCAE_v5 Jejunal Obstruction, CTCAE PT NCI Jejunal obstruction PT CTCAE_v5 ctcae5:C57832 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the jejunum. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the jejunum. Jejunal Ulcer, CTCAE Jejunal ulcer 10023177 C57832 Jejunal ulcer Jejunal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the jejunum. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the jejunum. CTCAE_v5 Jejunal Ulcer, CTCAE PT NCI Jejunal ulcer PT CTCAE_v5 ctcae5:C57838 A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. Malabsorption Malabsorption, CTCAE 10025476 C57838 Malabsorption Malabsorption A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. NCI A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea. CTCAE_v5 Malabsorption PT CTCAE_v5 Malabsorption, CTCAE PT NCI ctcae5:C57845 A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. Pancreatic Fistula, CTCAE Pancreatic fistula 10049192 C57845 Pancreatic fistula Pancreatic fistula A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site. CTCAE_v5 Pancreatic Fistula, CTCAE PT NCI Pancreatic fistula PT CTCAE_v5 ctcae5:C57849 A disorder in the gingival tissue around the teeth. A disorder in the gingival tissue around the teeth. Periodontal Disease, CTCAE Periodontal disease 10034536 C57849 Periodontal disease Periodontal disease A disorder in the gingival tissue around the teeth. NCI A disorder in the gingival tissue around the teeth. CTCAE_v5 Periodontal Disease, CTCAE PT NCI Periodontal disease PT CTCAE_v5 ctcae5:C57850 A disorder characterized by a necrotic process occurring in the peritoneum. A disorder characterized by a necrotic process occurring in the peritoneum. Peritoneal Necrosis, CTCAE Peritoneal necrosis 10065704 C57850 Peritoneal necrosis Peritoneal necrosis A disorder characterized by a necrotic process occurring in the peritoneum. NCI A disorder characterized by a necrotic process occurring in the peritoneum. CTCAE_v5 Peritoneal Necrosis, CTCAE PT NCI Peritoneal necrosis PT CTCAE_v5 ctcae5:C57851 A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. Pharyngeal Fistula, CTCAE Pharyngeal fistula 10034825 C57851 Pharyngeal fistula Pharyngeal fistula A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the pharynx and another organ or anatomic site. CTCAE_v5 Pharyngeal Fistula, CTCAE PT NCI Pharyngeal fistula PT CTCAE_v5 ctcae5:C57855 A disorder characterized by a necrotic process occurring in the pharynx. A disorder characterized by a necrotic process occurring in the pharynx. Pharyngeal Necrosis, CTCAE Pharyngeal necrosis 10065706 C57855 Pharyngeal necrosis Pharyngeal necrosis A disorder characterized by a necrotic process occurring in the pharynx. NCI A disorder characterized by a necrotic process occurring in the pharynx. CTCAE_v5 Pharyngeal Necrosis, CTCAE PT NCI Pharyngeal necrosis PT CTCAE_v5 ctcae5:C57857 A disorder characterized by inflammation of the rectum. A disorder characterized by inflammation of the rectum. Proctitis Proctitis, CTCAE 10036774 C57857 Proctitis Proctitis A disorder characterized by inflammation of the rectum. NCI A disorder characterized by inflammation of the rectum. CTCAE_v5 Proctitis PT CTCAE_v5 Proctitis, CTCAE PT NCI ctcae5:C57859 A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. Rectal Fistula, CTCAE Rectal fistula 10038062 C57859 Rectal fistula Rectal fistula A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the rectum and another organ or anatomic site. CTCAE_v5 Rectal Fistula, CTCAE PT NCI Rectal fistula PT CTCAE_v5 ctcae5:C57863 A disorder characterized by a necrotic process occurring in the rectal wall. A disorder characterized by a necrotic process occurring in the rectal wall. Rectal Necrosis, CTCAE Rectal necrosis 10065709 C57863 Rectal necrosis Rectal necrosis A disorder characterized by a necrotic process occurring in the rectal wall. NCI A disorder characterized by a necrotic process occurring in the rectal wall. CTCAE_v5 Rectal Necrosis, CTCAE PT NCI Rectal necrosis PT CTCAE_v5 ctcae5:C57864 A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. Rectal Obstruction, CTCAE Rectal obstruction 10065707 C57864 Rectal obstruction Rectal obstruction A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. NCI A disorder characterized by blockage of the normal flow of the intestinal contents in the rectum. CTCAE_v5 Rectal Obstruction, CTCAE PT NCI Rectal obstruction PT CTCAE_v5 ctcae5:C57867 A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the rectum. A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the rectum. Rectal Ulcer, CTCAE Rectal ulcer 10038080 C57867 Rectal ulcer Rectal ulcer A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the rectum. NCI A disorder characterized by a circumscribed, erosive lesion on the mucosal surface of the rectum. CTCAE_v5 Rectal Ulcer, CTCAE PT NCI Rectal ulcer PT CTCAE_v5 ctcae5:C57868 A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. Salivary Gland Fistula, CTCAE Salivary gland fistula 10039411 C57868 Salivary gland fistula Salivary gland fistula A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between a salivary gland and another organ or anatomic site. CTCAE_v5 Salivary Gland Fistula, CTCAE PT NCI Salivary gland fistula PT CTCAE_v5 ctcae5:C57896 A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. Vomiting Vomiting, CTCAE 10047700 C57896 Vomiting Vomiting A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. NCI A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. CTCAE_v5 Vomiting PT CTCAE_v5 Vomiting, CTCAE PT NCI ctcae5:C57898 A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. Alopecia Alopecia, CTCAE 10001760 C57898 Alopecia Alopecia A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. NCI A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given age and body location. CTCAE_v5 Alopecia PT CTCAE_v5 Alopecia, CTCAE PT NCI ctcae5:C57900 A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. Burn Burn, CTCAE 10006634 C57900 Burn Burn A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. NCI A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment. CTCAE_v5 Burn PT CTCAE_v5 Burn, CTCAE PT NCI ctcae5:C57901 A disorder characterized by inflammation of the lip. A disorder characterized by inflammation of the lip. Cheilitis Cheilitis, CTCAE 10008417 C57901 Cheilitis Cheilitis A disorder characterized by inflammation of the lip. NCI A disorder characterized by inflammation of the lip. CTCAE_v5 Cheilitis PT CTCAE_v5 Cheilitis, CTCAE PT NCI ctcae5:C57902 Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage Grade 1 Alopecia Grade 1 Alopecia, CTCAE 10001760 C57902 Grade 1 Alopecia Grade 1 Alopecia Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage NCI Hair loss of <50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage CTCAE_v5 Grade 1 Alopecia PT CTCAE_v5 Grade 1 Alopecia, CTCAE PT NCI ctcae5:C57904 Minimal symptoms; intervention not indicated Minimal symptoms; intervention not indicated Grade 1 Burn Grade 1 Burn, CTCAE 10006634 C57904 Grade 1 Burn Grade 1 Burn Minimal symptoms; intervention not indicated NCI Minimal symptoms; intervention not indicated CTCAE_v5 Grade 1 Burn PT CTCAE_v5 Grade 1 Burn, CTCAE PT NCI ctcae5:C57905 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Cheilitis Grade 1 Cheilitis, CTCAE 10008417 C57905 Grade 1 Cheilitis Grade 1 Cheilitis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Cheilitis PT CTCAE_v5 Grade 1 Cheilitis, CTCAE PT NCI ctcae5:C57907 Covering <10% BSA and no associated erythema or pruritus Covering <10% BSA and no associated erythema or pruritus Grade 1 Dry Skin, CTCAE Grade 1 Dry skin 10013786 C57907 Grade 1 Dry skin Grade 1 Dry skin Covering <10% BSA and no associated erythema or pruritus NCI Covering <10% BSA and no associated erythema or pruritus CTCAE_v5 Grade 1 Dry Skin, CTCAE PT NCI Grade 1 Dry skin PT CTCAE_v5 ctcae5:C57908 Asymptomatic; clinical or diagnostic observations only Asymptomatic; clinical or diagnostic observations only Grade 1 Flushing Grade 1 Flushing, CTCAE 10016825 C57908 Grade 1 Flushing Grade 1 Flushing Asymptomatic; clinical or diagnostic observations only NCI Asymptomatic; clinical or diagnostic observations only CTCAE_v5 Grade 1 Flushing PT CTCAE_v5 Grade 1 Flushing, CTCAE PT NCI ctcae5:C57913 Present Present Grade 1 Nail Changes, CTCAE Grade 1 Nail changes 10028689 C57913 Grade 1 Nail changes Grade 1 Nail changes Present NCI Present CTCAE_v5 Grade 1 Nail Changes, CTCAE PT NCI Grade 1 Nail changes PT CTCAE_v5 ctcae5:C57916 Painless erythema and erythema covering <10% BSA Painless erythema and erythema covering <10% BSA Grade 1 Photosensitivity Grade 1 Photosensitivity, CTCAE 10034966 C57916 Grade 1 Photosensitivity Grade 1 Photosensitivity Painless erythema and erythema covering <10% BSA NCI Painless erythema and erythema covering <10% BSA CTCAE_v5 Grade 1 Photosensitivity PT CTCAE_v5 Grade 1 Photosensitivity, CTCAE PT NCI ctcae5:C57917 Mild or localized; topical intervention indicated Mild or localized; topical intervention indicated Grade 1 Pruritus Grade 1 Pruritus, CTCAE 10037087 C57917 Grade 1 Pruritus Grade 1 Pruritus Mild or localized; topical intervention indicated NCI Mild or localized; topical intervention indicated CTCAE_v5 Grade 1 Pruritus PT CTCAE_v5 Grade 1 Pruritus, CTCAE PT NCI ctcae5:C57922 Covering <10% BSA; associated with telangiectasias or changes in skin color Covering <10% BSA; associated with telangiectasias or changes in skin color Grade 1 Skin Atrophy, CTCAE Grade 1 Skin atrophy 10040799 C57922 Grade 1 Skin atrophy Grade 1 Skin atrophy Covering <10% BSA; associated with telangiectasias or changes in skin color NCI Covering <10% BSA; associated with telangiectasias or changes in skin color CTCAE_v5 Grade 1 Skin Atrophy, CTCAE PT NCI Grade 1 Skin atrophy PT CTCAE_v5 ctcae5:C57925 Telangiectasias covering <10% BSA Telangiectasias covering <10% BSA Grade 1 Telangiectasia Grade 1 Telangiectasia, CTCAE 10043189 C57925 Grade 1 Telangiectasia Grade 1 Telangiectasia Telangiectasias covering <10% BSA NCI Telangiectasias covering <10% BSA CTCAE_v5 Grade 1 Telangiectasia PT CTCAE_v5 Grade 1 Telangiectasia, CTCAE PT NCI ctcae5:C57926 Urticarial lesions covering <10% BSA; topical intervention indicated Urticarial lesions covering <10% BSA; topical intervention indicated Grade 1 Urticaria Grade 1 Urticaria, CTCAE 10046735 C57926 Grade 1 Urticaria Grade 1 Urticaria Urticarial lesions covering <10% BSA; topical intervention indicated NCI Urticarial lesions covering <10% BSA; topical intervention indicated CTCAE_v5 Grade 1 Urticaria PT CTCAE_v5 Grade 1 Urticaria, CTCAE PT NCI ctcae5:C57927 Hair loss of >=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact Hair loss of >=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact Grade 2 Alopecia Grade 2 Alopecia, CTCAE 10001760 C57927 Grade 2 Alopecia Grade 2 Alopecia Hair loss of >=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact NCI Hair loss of >=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact CTCAE_v5 Grade 2 Alopecia PT CTCAE_v5 Grade 2 Alopecia, CTCAE PT NCI ctcae5:C57929 Medical intervention; minimal debridement indicated Medical intervention; minimal debridement indicated Grade 2 Burn Grade 2 Burn, CTCAE 10006634 C57929 Grade 2 Burn Grade 2 Burn Medical intervention; minimal debridement indicated NCI Medical intervention; minimal debridement indicated CTCAE_v5 Grade 2 Burn PT CTCAE_v5 Grade 2 Burn, CTCAE PT NCI ctcae5:C57930 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Cheilitis Grade 2 Cheilitis, CTCAE 10008417 C57930 Grade 2 Cheilitis Grade 2 Cheilitis Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Cheilitis PT CTCAE_v5 Grade 2 Cheilitis, CTCAE PT NCI ctcae5:C57932 Covering 10-30% BSA and associated with erythema or pruritus; limiting instrumental ADL Covering 10-30% BSA and associated with erythema or pruritus; limiting instrumental ADL Grade 2 Dry Skin, CTCAE Grade 2 Dry skin 10013786 C57932 Grade 2 Dry skin Grade 2 Dry skin Covering 10-30% BSA and associated with erythema or pruritus; limiting instrumental ADL NCI Covering 10-30% BSA and associated with erythema or pruritus; limiting instrumental ADL CTCAE_v5 Grade 2 Dry Skin, CTCAE PT NCI Grade 2 Dry skin PT CTCAE_v5 ctcae5:C57933 Moderate symptoms; limiting instrumental ADL Moderate symptoms; limiting instrumental ADL Grade 2 Flushing Grade 2 Flushing, CTCAE 10016825 C57933 Grade 2 Flushing Grade 2 Flushing Moderate symptoms; limiting instrumental ADL NCI Moderate symptoms; limiting instrumental ADL CTCAE_v5 Grade 2 Flushing PT CTCAE_v5 Grade 2 Flushing, CTCAE PT NCI ctcae5:C57941 Tender erythema covering 10-30% BSA Tender erythema covering 10-30% BSA Grade 2 Photosensitivity Grade 2 Photosensitivity, CTCAE 10034966 C57941 Grade 2 Photosensitivity Grade 2 Photosensitivity Tender erythema covering 10-30% BSA NCI Tender erythema covering 10-30% BSA CTCAE_v5 Grade 2 Photosensitivity PT CTCAE_v5 Grade 2 Photosensitivity, CTCAE PT NCI ctcae5:C57942 Widespread and intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); oral intervention indicated; limiting instrumental ADL Widespread and intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); oral intervention indicated; limiting instrumental ADL Grade 2 Pruritus Grade 2 Pruritus, CTCAE 10037087 C57942 Grade 2 Pruritus Grade 2 Pruritus Widespread and intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); oral intervention indicated; limiting instrumental ADL NCI Widespread and intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); oral intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Pruritus PT CTCAE_v5 Grade 2 Pruritus, CTCAE PT NCI ctcae5:C57948 Covering 10-30% BSA; associated with striae or adnexal structure loss Covering 10-30% BSA; associated with striae or adnexal structure loss Grade 2 Skin Atrophy, CTCAE Grade 2 Skin atrophy 10040799 C57948 Grade 2 Skin atrophy Grade 2 Skin atrophy Covering 10-30% BSA; associated with striae or adnexal structure loss NCI Covering 10-30% BSA; associated with striae or adnexal structure loss CTCAE_v5 Grade 2 Skin Atrophy, CTCAE PT NCI Grade 2 Skin atrophy PT CTCAE_v5 ctcae5:C57952 Telangiectasias covering >=10% BSA; associated with psychosocial impact Telangiectasias covering >=10% BSA; associated with psychosocial impact Grade 2 Telangiectasia Grade 2 Telangiectasia, CTCAE 10043189 C57952 Grade 2 Telangiectasia Grade 2 Telangiectasia Telangiectasias covering >=10% BSA; associated with psychosocial impact NCI Telangiectasias covering >=10% BSA; associated with psychosocial impact CTCAE_v5 Grade 2 Telangiectasia PT CTCAE_v5 Grade 2 Telangiectasia, CTCAE PT NCI ctcae5:C57954 Urticarial lesions covering 10-30% BSA; oral intervention indicated Urticarial lesions covering 10-30% BSA; oral intervention indicated Grade 2 Urticaria Grade 2 Urticaria, CTCAE 10046735 C57954 Grade 2 Urticaria Grade 2 Urticaria Urticarial lesions covering 10-30% BSA; oral intervention indicated NCI Urticarial lesions covering 10-30% BSA; oral intervention indicated CTCAE_v5 Grade 2 Urticaria PT CTCAE_v5 Grade 2 Urticaria, CTCAE PT NCI ctcae5:C57955 Moderate to major debridement or reconstruction indicated Moderate to major debridement or reconstruction indicated Grade 3 Burn Grade 3 Burn, CTCAE 10006634 C57955 Grade 3 Burn Grade 3 Burn Moderate to major debridement or reconstruction indicated NCI Moderate to major debridement or reconstruction indicated CTCAE_v5 Grade 3 Burn PT CTCAE_v5 Grade 3 Burn, CTCAE PT NCI ctcae5:C57956 Severe symptoms; limiting self care ADL; intervention indicated Severe symptoms; limiting self care ADL; intervention indicated Grade 3 Cheilitis Grade 3 Cheilitis, CTCAE 10008417 C57956 Grade 3 Cheilitis Grade 3 Cheilitis Severe symptoms; limiting self care ADL; intervention indicated NCI Severe symptoms; limiting self care ADL; intervention indicated CTCAE_v5 Grade 3 Cheilitis PT CTCAE_v5 Grade 3 Cheilitis, CTCAE PT NCI ctcae5:C57958 Covering >30% BSA and associated with pruritus; limiting self care ADL Covering >30% BSA and associated with pruritus; limiting self care ADL Grade 3 Dry Skin, CTCAE Grade 3 Dry skin 10013786 C57958 Grade 3 Dry skin Grade 3 Dry skin Covering >30% BSA and associated with pruritus; limiting self care ADL NCI Covering >30% BSA and associated with pruritus; limiting self care ADL CTCAE_v5 Grade 3 Dry Skin, CTCAE PT NCI Grade 3 Dry skin PT CTCAE_v5 ctcae5:C57964 Erythema covering >30% BSA and erythema with blistering; photosensitivity; oral corticosteroid therapy indicated; pain control indicated (e.g., narcotics or NSAIDs) Erythema covering >30% BSA and erythema with blistering; photosensitivity; oral corticosteroid therapy indicated; pain control indicated (e.g., narcotics or NSAIDs) Grade 3 Photosensitivity Grade 3 Photosensitivity, CTCAE 10034966 C57964 Grade 3 Photosensitivity Grade 3 Photosensitivity Erythema covering >30% BSA and erythema with blistering; photosensitivity; oral corticosteroid therapy indicated; pain control indicated (e.g., narcotics or NSAIDs) NCI Erythema covering >30% BSA and erythema with blistering; photosensitivity; oral corticosteroid therapy indicated; pain control indicated (e.g., narcotics or NSAIDs) CTCAE_v5 Grade 3 Photosensitivity PT CTCAE_v5 Grade 3 Photosensitivity, CTCAE PT NCI ctcae5:C57965 Widespread and constant; limiting self care ADL or sleep; systemic corticosteroid or immunosuppressive therapy indicated Widespread and constant; limiting self care ADL or sleep; systemic corticosteroid or immunosuppressive therapy indicated Grade 3 Pruritus Grade 3 Pruritus, CTCAE 10037087 C57965 Grade 3 Pruritus Grade 3 Pruritus Widespread and constant; limiting self care ADL or sleep; systemic corticosteroid or immunosuppressive therapy indicated NCI Widespread and constant; limiting self care ADL or sleep; systemic corticosteroid or immunosuppressive therapy indicated CTCAE_v5 Grade 3 Pruritus PT CTCAE_v5 Grade 3 Pruritus, CTCAE PT NCI ctcae5:C57974 Urticarial lesions covering >30% BSA; IV intervention indicated Urticarial lesions covering >30% BSA; IV intervention indicated Grade 3 Urticaria Grade 3 Urticaria, CTCAE 10046735 C57974 Grade 3 Urticaria Grade 3 Urticaria Urticarial lesions covering >30% BSA; IV intervention indicated NCI Urticarial lesions covering >30% BSA; IV intervention indicated CTCAE_v5 Grade 3 Urticaria PT CTCAE_v5 Grade 3 Urticaria, CTCAE PT NCI ctcae5:C57975 Life-threatening consequences Life-threatening consequences Grade 4 Burn Grade 4 Burn, CTCAE 10006634 C57975 Grade 4 Burn Grade 4 Burn Life-threatening consequences NCI Life-threatening consequences CTCAE_v5 Grade 4 Burn PT CTCAE_v5 Grade 4 Burn, CTCAE PT NCI ctcae5:C57979 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Photosensitivity Grade 4 Photosensitivity, CTCAE 10034966 C57979 Grade 4 Photosensitivity Grade 4 Photosensitivity Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Photosensitivity PT CTCAE_v5 Grade 4 Photosensitivity, CTCAE PT NCI ctcae5:C57985 Death Death Grade 5 Burn Grade 5 Burn, CTCAE 10006634 C57985 Grade 5 Burn Grade 5 Burn Death NCI Death CTCAE_v5 Grade 5 Burn PT CTCAE_v5 Grade 5 Burn, CTCAE PT NCI ctcae5:C57989 Death Death Grade 5 Photosensitivity Grade 5 Photosensitivity, CTCAE 10034966 C57989 Grade 5 Photosensitivity Grade 5 Photosensitivity Death NCI Death CTCAE_v5 Grade 5 Photosensitivity PT CTCAE_v5 Grade 5 Photosensitivity, CTCAE PT NCI ctcae5:C57996 A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. Dry Skin, CTCAE Dry skin 10013786 C57996 Dry skin Dry skin A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. NCI A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture. CTCAE_v5 Dry Skin, CTCAE PT NCI Dry skin PT CTCAE_v5 ctcae5:C58005 A disorder characterized by an increase in sensitivity of the skin to light. A disorder characterized by an increase in sensitivity of the skin to light. Photosensitivity Photosensitivity, CTCAE 10034966 C58005 Photosensitivity Photosensitivity A disorder characterized by an increase in sensitivity of the skin to light. NCI A disorder characterized by an increase in sensitivity of the skin to light. CTCAE_v5 Photosensitivity PT CTCAE_v5 Photosensitivity, CTCAE PT NCI ctcae5:C58006 A disorder characterized by an intense itching sensation. A disorder characterized by an intense itching sensation. Pruritus Pruritus, CTCAE 10037087 C58006 Pruritus Pruritus A disorder characterized by an intense itching sensation. NCI A disorder characterized by an intense itching sensation. CTCAE_v5 Pruritus PT CTCAE_v5 Pruritus, CTCAE PT NCI ctcae5:C58019 A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. Urticaria Urticaria, CTCAE 10046735 C58019 Urticaria Urticaria A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. NCI A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined red margins. CTCAE_v5 Urticaria PT CTCAE_v5 Urticaria, CTCAE PT NCI ctcae5:C58020 A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Adult Respiratory Distress Syndrome, CTCAE Adult respiratory distress syndrome 10001409 C58020 Adult respiratory distress syndrome Adult respiratory distress syndrome A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. NCI A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. CTCAE_v5 Adult Respiratory Distress Syndrome, CTCAE PT NCI Adult respiratory distress syndrome PT CTCAE_v5 ctcae5:C58022 A disorder characterized by the collapse of part or the entire lung. A disorder characterized by the collapse of part or the entire lung. Atelectasis Atelectasis, CTCAE 10003598 C58022 Atelectasis Atelectasis A disorder characterized by the collapse of part or the entire lung. NCI A disorder characterized by the collapse of part or the entire lung. CTCAE_v5 Atelectasis PT CTCAE_v5 Atelectasis, CTCAE PT NCI ctcae5:C58027 A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. Chylothorax Chylothorax, CTCAE 10051228 C58027 Chylothorax Chylothorax A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. NCI A disorder characterized by milky pleural effusion (abnormal collection of fluid) resulting from accumulation of lymph fluid in the pleural cavity. CTCAE_v5 Chylothorax PT CTCAE_v5 Chylothorax, CTCAE PT NCI ctcae5:C58028 A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. Cough Cough, CTCAE 10011224 C58028 Cough Cough A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. NCI A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. CTCAE_v5 Cough PT CTCAE_v5 Cough, CTCAE PT NCI ctcae5:C58029 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Aspiration Grade 1 Aspiration, CTCAE 10003504 C58029 Grade 1 Aspiration Grade 1 Aspiration Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Aspiration PT CTCAE_v5 Grade 1 Aspiration, CTCAE PT NCI ctcae5:C58030 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Atelectasis Grade 1 Atelectasis, CTCAE 10003598 C58030 Grade 1 Atelectasis Grade 1 Atelectasis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Atelectasis PT CTCAE_v5 Grade 1 Atelectasis, CTCAE PT NCI ctcae5:C58035 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Chylothorax Grade 1 Chylothorax, CTCAE 10051228 C58035 Grade 1 Chylothorax Grade 1 Chylothorax Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Chylothorax PT CTCAE_v5 Grade 1 Chylothorax, CTCAE PT NCI ctcae5:C58036 Mild symptoms; nonprescription intervention indicated Mild symptoms; nonprescription intervention indicated Grade 1 Cough Grade 1 Cough, CTCAE 10011224 C58036 Grade 1 Cough Grade 1 Cough Mild symptoms; nonprescription intervention indicated NCI Mild symptoms; nonprescription intervention indicated CTCAE_v5 Grade 1 Cough PT CTCAE_v5 Grade 1 Cough, CTCAE PT NCI ctcae5:C58037 Shortness of breath with moderate exertion Shortness of breath with moderate exertion Grade 1 Dyspnea Grade 1 Dyspnea, CTCAE 10013963 C58037 Grade 1 Dyspnea Grade 1 Dyspnea Shortness of breath with moderate exertion NCI Shortness of breath with moderate exertion CTCAE_v5 Grade 1 Dyspnea PT CTCAE_v5 Grade 1 Dyspnea, CTCAE PT NCI ctcae5:C58041 Asymptomatic Asymptomatic Grade 1 Laryngeal Fistula, CTCAE Grade 1 Laryngeal fistula 10065786 C58041 Grade 1 Laryngeal fistula Grade 1 Laryngeal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Laryngeal Fistula, CTCAE PT NCI Grade 1 Laryngeal fistula PT CTCAE_v5 ctcae5:C58052 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Pneumothorax Grade 1 Pneumothorax, CTCAE 10035759 C58052 Grade 1 Pneumothorax Grade 1 Pneumothorax Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Pneumothorax PT CTCAE_v5 Grade 1 Pneumothorax, CTCAE PT NCI ctcae5:C58054 Asymptomatic Asymptomatic Grade 1 Tracheal Fistula, CTCAE Grade 1 Tracheal fistula 10065787 C58054 Grade 1 Tracheal fistula Grade 1 Tracheal fistula Asymptomatic NCI Asymptomatic CTCAE_v5 Grade 1 Tracheal Fistula, CTCAE PT NCI Grade 1 Tracheal fistula PT CTCAE_v5 ctcae5:C58058 Altered eating habits; coughing or choking episodes after eating or swallowing; medical intervention indicated (e.g., suction or oxygen) Altered eating habits; coughing or choking episodes after eating or swallowing; medical intervention indicated (e.g., suction or oxygen) Grade 2 Aspiration Grade 2 Aspiration, CTCAE 10003504 C58058 Grade 2 Aspiration Grade 2 Aspiration Altered eating habits; coughing or choking episodes after eating or swallowing; medical intervention indicated (e.g., suction or oxygen) NCI Altered eating habits; coughing or choking episodes after eating or swallowing; medical intervention indicated (e.g., suction or oxygen) CTCAE_v5 Grade 2 Aspiration PT CTCAE_v5 Grade 2 Aspiration, CTCAE PT NCI ctcae5:C58059 Symptomatic (e.g., dyspnea, cough); medical intervention indicated (e.g., chest physiotherapy, suctioning); bronchoscopic suctioning Symptomatic (e.g., dyspnea, cough); medical intervention indicated (e.g., chest physiotherapy, suctioning); bronchoscopic suctioning Grade 2 Atelectasis Grade 2 Atelectasis, CTCAE 10003598 C58059 Grade 2 Atelectasis Grade 2 Atelectasis Symptomatic (e.g., dyspnea, cough); medical intervention indicated (e.g., chest physiotherapy, suctioning); bronchoscopic suctioning NCI Symptomatic (e.g., dyspnea, cough); medical intervention indicated (e.g., chest physiotherapy, suctioning); bronchoscopic suctioning CTCAE_v5 Grade 2 Atelectasis PT CTCAE_v5 Grade 2 Atelectasis, CTCAE PT NCI ctcae5:C58064 Symptomatic; medical intervention indicated (e.g., fat-restricted diet); thoracentesis or tube drainage indicated Symptomatic; medical intervention indicated (e.g., fat-restricted diet); thoracentesis or tube drainage indicated Grade 2 Chylothorax Grade 2 Chylothorax, CTCAE 10051228 C58064 Grade 2 Chylothorax Grade 2 Chylothorax Symptomatic; medical intervention indicated (e.g., fat-restricted diet); thoracentesis or tube drainage indicated NCI Symptomatic; medical intervention indicated (e.g., fat-restricted diet); thoracentesis or tube drainage indicated CTCAE_v5 Grade 2 Chylothorax PT CTCAE_v5 Grade 2 Chylothorax, CTCAE PT NCI ctcae5:C58065 Moderate symptoms, medical intervention indicated; limiting instrumental ADL Moderate symptoms, medical intervention indicated; limiting instrumental ADL Grade 2 Cough Grade 2 Cough, CTCAE 10011224 C58065 Grade 2 Cough Grade 2 Cough Moderate symptoms, medical intervention indicated; limiting instrumental ADL NCI Moderate symptoms, medical intervention indicated; limiting instrumental ADL CTCAE_v5 Grade 2 Cough PT CTCAE_v5 Grade 2 Cough, CTCAE PT NCI ctcae5:C58066 Shortness of breath with minimal exertion; limiting instrumental ADL Shortness of breath with minimal exertion; limiting instrumental ADL Grade 2 Dyspnea Grade 2 Dyspnea, CTCAE 10013963 C58066 Grade 2 Dyspnea Grade 2 Dyspnea Shortness of breath with minimal exertion; limiting instrumental ADL NCI Shortness of breath with minimal exertion; limiting instrumental ADL CTCAE_v5 Grade 2 Dyspnea PT CTCAE_v5 Grade 2 Dyspnea, CTCAE PT NCI ctcae5:C58069 Decreased oxygen saturation with exercise (e.g., pulse oximeter <88%); intermittent supplemental oxygen Decreased oxygen saturation with exercise (e.g., pulse oximeter <88%); intermittent supplemental oxygen Grade 2 Hypoxia Grade 2 Hypoxia, CTCAE 10021143 C58069 Grade 2 Hypoxia Grade 2 Hypoxia Decreased oxygen saturation with exercise (e.g., pulse oximeter <88%); intermittent supplemental oxygen NCI Decreased oxygen saturation with exercise (e.g., pulse oximeter <88%); intermittent supplemental oxygen CTCAE_v5 Grade 2 Hypoxia PT CTCAE_v5 Grade 2 Hypoxia, CTCAE PT NCI ctcae5:C58071 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Laryngeal Fistula, CTCAE Grade 2 Laryngeal fistula 10065786 C58071 Grade 2 Laryngeal fistula Grade 2 Laryngeal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Laryngeal Fistula, CTCAE PT NCI Grade 2 Laryngeal fistula PT CTCAE_v5 ctcae5:C58082 Symptomatic; intervention indicated Symptomatic; intervention indicated Grade 2 Pneumothorax Grade 2 Pneumothorax, CTCAE 10035759 C58082 Grade 2 Pneumothorax Grade 2 Pneumothorax Symptomatic; intervention indicated NCI Symptomatic; intervention indicated CTCAE_v5 Grade 2 Pneumothorax PT CTCAE_v5 Grade 2 Pneumothorax, CTCAE PT NCI ctcae5:C58086 Symptomatic, invasive intervention not indicated Symptomatic, invasive intervention not indicated Grade 2 Tracheal Fistula, CTCAE Grade 2 Tracheal fistula 10065787 C58086 Grade 2 Tracheal fistula Grade 2 Tracheal fistula Symptomatic, invasive intervention not indicated NCI Symptomatic, invasive intervention not indicated CTCAE_v5 Grade 2 Tracheal Fistula, CTCAE PT NCI Grade 2 Tracheal fistula PT CTCAE_v5 ctcae5:C58090 Present with radiologic findings; intubation not indicated Present with radiologic findings; intubation not indicated Grade 3 Adult Respiratory Distress Syndrome, CTCAE Grade 3 Adult respiratory distress syndrome 10001409 C58090 Grade 3 Adult respiratory distress syndrome Grade 3 Adult respiratory distress syndrome Present with radiologic findings; intubation not indicated NCI Present with radiologic findings; intubation not indicated CTCAE_v5 Grade 3 Adult Respiratory Distress Syndrome, CTCAE PT NCI Grade 3 Adult respiratory distress syndrome PT CTCAE_v5 ctcae5:C58091 Dyspnea and pneumonia symptoms (e.g., aspiration pneumonia); hospitalization indicated; unable to aliment orally Dyspnea and pneumonia symptoms (e.g., aspiration pneumonia); hospitalization indicated; unable to aliment orally Grade 3 Aspiration Grade 3 Aspiration, CTCAE 10003504 C58091 Grade 3 Aspiration Grade 3 Aspiration Dyspnea and pneumonia symptoms (e.g., aspiration pneumonia); hospitalization indicated; unable to aliment orally NCI Dyspnea and pneumonia symptoms (e.g., aspiration pneumonia); hospitalization indicated; unable to aliment orally CTCAE_v5 Grade 3 Aspiration PT CTCAE_v5 Grade 3 Aspiration, CTCAE PT NCI ctcae5:C58092 Supplemental oxygen indicated; hospitalization or elective operative intervention indicated (e.g., stent, laser) Supplemental oxygen indicated; hospitalization or elective operative intervention indicated (e.g., stent, laser) Grade 3 Atelectasis Grade 3 Atelectasis, CTCAE 10003598 C58092 Grade 3 Atelectasis Grade 3 Atelectasis Supplemental oxygen indicated; hospitalization or elective operative intervention indicated (e.g., stent, laser) NCI Supplemental oxygen indicated; hospitalization or elective operative intervention indicated (e.g., stent, laser) CTCAE_v5 Grade 3 Atelectasis PT CTCAE_v5 Grade 3 Atelectasis, CTCAE PT NCI ctcae5:C58097 Severe symptoms; elective operative intervention indicated Severe symptoms; elective operative intervention indicated Grade 3 Chylothorax Grade 3 Chylothorax, CTCAE 10051228 C58097 Grade 3 Chylothorax Grade 3 Chylothorax Severe symptoms; elective operative intervention indicated NCI Severe symptoms; elective operative intervention indicated CTCAE_v5 Grade 3 Chylothorax PT CTCAE_v5 Grade 3 Chylothorax, CTCAE PT NCI ctcae5:C58098 Severe symptoms; limiting self care ADL Severe symptoms; limiting self care ADL Grade 3 Cough Grade 3 Cough, CTCAE 10011224 C58098 Grade 3 Cough Grade 3 Cough Severe symptoms; limiting self care ADL NCI Severe symptoms; limiting self care ADL CTCAE_v5 Grade 3 Cough PT CTCAE_v5 Grade 3 Cough, CTCAE PT NCI ctcae5:C58099 Shortness of breath at rest; limiting self care ADL Shortness of breath at rest; limiting self care ADL Grade 3 Dyspnea Grade 3 Dyspnea, CTCAE 10013963 C58099 Grade 3 Dyspnea Grade 3 Dyspnea Shortness of breath at rest; limiting self care ADL NCI Shortness of breath at rest; limiting self care ADL CTCAE_v5 Grade 3 Dyspnea PT CTCAE_v5 Grade 3 Dyspnea, CTCAE PT NCI ctcae5:C58102 Decreased oxygen saturation at rest (e.g., pulse oximeter <88% or PaO2 <=55 mm Hg) Decreased oxygen saturation at rest (e.g., pulse oximeter <88% or PaO2 <=55 mm Hg) Grade 3 Hypoxia Grade 3 Hypoxia, CTCAE 10021143 C58102 Grade 3 Hypoxia Grade 3 Hypoxia Decreased oxygen saturation at rest (e.g., pulse oximeter <88% or PaO2 <=55 mm Hg) NCI Decreased oxygen saturation at rest (e.g., pulse oximeter <88% or PaO2 <=55 mm Hg) CTCAE_v5 Grade 3 Hypoxia PT CTCAE_v5 Grade 3 Hypoxia, CTCAE PT NCI ctcae5:C58104 Invasive intervention indicated Invasive intervention indicated Grade 3 Laryngeal Fistula, CTCAE Grade 3 Laryngeal fistula 10065786 C58104 Grade 3 Laryngeal fistula Grade 3 Laryngeal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Laryngeal Fistula, CTCAE PT NCI Grade 3 Laryngeal fistula PT CTCAE_v5 ctcae5:C58115 Sclerosis and/or operative intervention indicated; hospitalization indicated Sclerosis and/or operative intervention indicated; hospitalization indicated Grade 3 Pneumothorax Grade 3 Pneumothorax, CTCAE 10035759 C58115 Grade 3 Pneumothorax Grade 3 Pneumothorax Sclerosis and/or operative intervention indicated; hospitalization indicated NCI Sclerosis and/or operative intervention indicated; hospitalization indicated CTCAE_v5 Grade 3 Pneumothorax PT CTCAE_v5 Grade 3 Pneumothorax, CTCAE PT NCI ctcae5:C58119 Invasive intervention indicated Invasive intervention indicated Grade 3 Tracheal Fistula, CTCAE Grade 3 Tracheal fistula 10065787 C58119 Grade 3 Tracheal fistula Grade 3 Tracheal fistula Invasive intervention indicated NCI Invasive intervention indicated CTCAE_v5 Grade 3 Tracheal Fistula, CTCAE PT NCI Grade 3 Tracheal fistula PT CTCAE_v5 ctcae5:C58123 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Adult Respiratory Distress Syndrome, CTCAE Grade 4 Adult respiratory distress syndrome 10001409 C58123 Grade 4 Adult respiratory distress syndrome Grade 4 Adult respiratory distress syndrome Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Adult Respiratory Distress Syndrome, CTCAE PT NCI Grade 4 Adult respiratory distress syndrome PT CTCAE_v5 ctcae5:C58124 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Aspiration Grade 4 Aspiration, CTCAE 10003504 C58124 Grade 4 Aspiration Grade 4 Aspiration Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Aspiration PT CTCAE_v5 Grade 4 Aspiration, CTCAE PT NCI ctcae5:C58125 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Atelectasis Grade 4 Atelectasis, CTCAE 10003598 C58125 Grade 4 Atelectasis Grade 4 Atelectasis Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Atelectasis PT CTCAE_v5 Grade 4 Atelectasis, CTCAE PT NCI ctcae5:C58130 Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated Grade 4 Chylothorax Grade 4 Chylothorax, CTCAE 10051228 C58130 Grade 4 Chylothorax Grade 4 Chylothorax Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated NCI Life-threatening respiratory or hemodynamic compromise; intubation or urgent intervention indicated CTCAE_v5 Grade 4 Chylothorax PT CTCAE_v5 Grade 4 Chylothorax, CTCAE PT NCI ctcae5:C58131 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Dyspnea Grade 4 Dyspnea, CTCAE 10013963 C58131 Grade 4 Dyspnea Grade 4 Dyspnea Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Dyspnea PT CTCAE_v5 Grade 4 Dyspnea, CTCAE PT NCI ctcae5:C58133 Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) Grade 4 Hypoxia Grade 4 Hypoxia, CTCAE 10021143 C58133 Grade 4 Hypoxia Grade 4 Hypoxia Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) NCI Life-threatening airway compromise; urgent intervention indicated (e.g., tracheotomy or intubation) CTCAE_v5 Grade 4 Hypoxia PT CTCAE_v5 Grade 4 Hypoxia, CTCAE PT NCI ctcae5:C58135 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Laryngeal Fistula, CTCAE Grade 4 Laryngeal fistula 10065786 C58135 Grade 4 Laryngeal fistula Grade 4 Laryngeal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Laryngeal Fistula, CTCAE PT NCI Grade 4 Laryngeal fistula PT CTCAE_v5 ctcae5:C58146 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pneumothorax Grade 4 Pneumothorax, CTCAE 10035759 C58146 Grade 4 Pneumothorax Grade 4 Pneumothorax Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pneumothorax PT CTCAE_v5 Grade 4 Pneumothorax, CTCAE PT NCI ctcae5:C58150 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Tracheal Fistula, CTCAE Grade 4 Tracheal fistula 10065787 C58150 Grade 4 Tracheal fistula Grade 4 Tracheal fistula Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Tracheal Fistula, CTCAE PT NCI Grade 4 Tracheal fistula PT CTCAE_v5 ctcae5:C58154 Death Death Grade 5 Adult Respiratory Distress Syndrome, CTCAE Grade 5 Adult respiratory distress syndrome 10001409 C58154 Grade 5 Adult respiratory distress syndrome Grade 5 Adult respiratory distress syndrome Death NCI Death CTCAE_v5 Grade 5 Adult Respiratory Distress Syndrome, CTCAE PT NCI Grade 5 Adult respiratory distress syndrome PT CTCAE_v5 ctcae5:C58155 Death Death Grade 5 Aspiration Grade 5 Aspiration, CTCAE 10003504 C58155 Grade 5 Aspiration Grade 5 Aspiration Death NCI Death CTCAE_v5 Grade 5 Aspiration PT CTCAE_v5 Grade 5 Aspiration, CTCAE PT NCI ctcae5:C58156 Death Death Grade 5 Atelectasis Grade 5 Atelectasis, CTCAE 10003598 C58156 Grade 5 Atelectasis Grade 5 Atelectasis Death NCI Death CTCAE_v5 Grade 5 Atelectasis PT CTCAE_v5 Grade 5 Atelectasis, CTCAE PT NCI ctcae5:C58161 Death Death Grade 5 Chylothorax Grade 5 Chylothorax, CTCAE 10051228 C58161 Grade 5 Chylothorax Grade 5 Chylothorax Death NCI Death CTCAE_v5 Grade 5 Chylothorax PT CTCAE_v5 Grade 5 Chylothorax, CTCAE PT NCI ctcae5:C58162 Death Death Grade 5 Dyspnea Grade 5 Dyspnea, CTCAE 10013963 C58162 Grade 5 Dyspnea Grade 5 Dyspnea Death NCI Death CTCAE_v5 Grade 5 Dyspnea PT CTCAE_v5 Grade 5 Dyspnea, CTCAE PT NCI ctcae5:C58164 Death Death Grade 5 Hypoxia Grade 5 Hypoxia, CTCAE 10021143 C58164 Grade 5 Hypoxia Grade 5 Hypoxia Death NCI Death CTCAE_v5 Grade 5 Hypoxia PT CTCAE_v5 Grade 5 Hypoxia, CTCAE PT NCI ctcae5:C58166 Death Death Grade 5 Laryngeal Fistula, CTCAE Grade 5 Laryngeal fistula 10065786 C58166 Grade 5 Laryngeal fistula Grade 5 Laryngeal fistula Death NCI Death CTCAE_v5 Grade 5 Laryngeal Fistula, CTCAE PT NCI Grade 5 Laryngeal fistula PT CTCAE_v5 ctcae5:C58177 Death Death Grade 5 Pneumothorax Grade 5 Pneumothorax, CTCAE 10035759 C58177 Grade 5 Pneumothorax Grade 5 Pneumothorax Death NCI Death CTCAE_v5 Grade 5 Pneumothorax PT CTCAE_v5 Grade 5 Pneumothorax, CTCAE PT NCI ctcae5:C58181 Death Death Grade 5 Tracheal Fistula, CTCAE Grade 5 Tracheal fistula 10065787 C58181 Grade 5 Tracheal fistula Grade 5 Tracheal fistula Death NCI Death CTCAE_v5 Grade 5 Tracheal Fistula, CTCAE PT NCI Grade 5 Tracheal fistula PT CTCAE_v5 ctcae5:C58185 A disorder characterized by an uncomfortable sensation of difficulty breathing. A disorder characterized by an uncomfortable sensation of difficulty breathing. Dyspnea Dyspnea, CTCAE 10013963 C58185 Dyspnea Dyspnea A disorder characterized by an uncomfortable sensation of difficulty breathing. NCI A disorder characterized by an uncomfortable sensation of difficulty breathing. CTCAE_v5 Dyspnea PT CTCAE_v5 Dyspnea, CTCAE PT NCI ctcae5:C58188 A disorder characterized by a decrease in the level of oxygen in the body. A disorder characterized by a decrease in the level of oxygen in the body. Hypoxia Hypoxia, CTCAE 10021143 C58188 Hypoxia Hypoxia A disorder characterized by a decrease in the level of oxygen in the body. NCI A disorder characterized by a decrease in the level of oxygen in the body. CTCAE_v5 Hypoxia PT CTCAE_v5 Hypoxia, CTCAE PT NCI ctcae5:C58190 A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. Laryngeal Fistula, CTCAE Laryngeal fistula 10065786 C58190 Laryngeal fistula Laryngeal fistula A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the larynx and another organ or anatomic site. CTCAE_v5 Laryngeal Fistula, CTCAE PT NCI Laryngeal fistula PT CTCAE_v5 ctcae5:C58201 A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. Pneumothorax Pneumothorax, CTCAE 10035759 C58201 Pneumothorax Pneumothorax A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. NCI A disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung. CTCAE_v5 Pneumothorax PT CTCAE_v5 Pneumothorax, CTCAE PT NCI ctcae5:C58205 A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. Tracheal Fistula, CTCAE Tracheal fistula 10065787 C58205 Tracheal fistula Tracheal fistula A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. NCI A disorder characterized by an abnormal communication between the trachea and another organ or anatomic site. CTCAE_v5 Tracheal Fistula, CTCAE PT NCI Tracheal fistula PT CTCAE_v5 ctcae5:C58215 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Exostosis Grade 1 Exostosis, CTCAE 10015688 C58215 Grade 1 Exostosis Grade 1 Exostosis Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Exostosis PT CTCAE_v5 Grade 1 Exostosis, CTCAE PT NCI ctcae5:C58220 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Fracture Grade 1 Fracture, CTCAE 10017076 C58220 Grade 1 Fracture Grade 1 Fracture Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Fracture PT CTCAE_v5 Grade 1 Fracture, CTCAE PT NCI ctcae5:C58221 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Joint Effusion, CTCAE Grade 1 Joint effusion 10023215 C58221 Grade 1 Joint effusion Grade 1 Joint effusion Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Joint Effusion, CTCAE PT NCI Grade 1 Joint effusion PT CTCAE_v5 ctcae5:C58230 Mild pain Mild pain Grade 1 Myositis Grade 1 Myositis, CTCAE 10028653 C58230 Grade 1 Myositis Grade 1 Myositis Mild pain NCI Mild pain CTCAE_v5 Grade 1 Myositis PT CTCAE_v5 Grade 1 Myositis, CTCAE PT NCI ctcae5:C58233 Adult: Radiologic evidence of osteoporosis or Bone Mineral Density (BMD) t-score -1 to -2.5 (osteopenia); Pediatric: Radiologic evidence of low BMD with z score of <= -2.0 and no history of significant fractures Adult: Radiologic evidence of osteoporosis or Bone Mineral Density (BMD) t-score -1 to -2.5 (osteopenia); Pediatric: Radiologic evidence of low BMD with z score of <= -2.0 and no history of significant fractures Grade 1 Osteoporosis Grade 1 Osteoporosis, CTCAE 10031282 C58233 Grade 1 Osteoporosis Grade 1 Osteoporosis Adult: Radiologic evidence of osteoporosis or Bone Mineral Density (BMD) t-score -1 to -2.5 (osteopenia); Pediatric: Radiologic evidence of low BMD with z score of <= -2.0 and no history of significant fractures NCI Adult: Radiologic evidence of osteoporosis or Bone Mineral Density (BMD) t-score -1 to -2.5 (osteopenia); Pediatric: Radiologic evidence of low BMD with z score of <= -2.0 and no history of significant fractures CTCAE_v5 Grade 1 Osteoporosis PT CTCAE_v5 Grade 1 Osteoporosis, CTCAE PT NCI ctcae5:C58236 Asymptomatic; clinical or diagnostic observations only; intervention not indicated Asymptomatic; clinical or diagnostic observations only; intervention not indicated Grade 1 Seroma Grade 1 Seroma, CTCAE 10040102 C58236 Grade 1 Seroma Grade 1 Seroma Asymptomatic; clinical or diagnostic observations only; intervention not indicated NCI Asymptomatic; clinical or diagnostic observations only; intervention not indicated CTCAE_v5 Grade 1 Seroma PT CTCAE_v5 Grade 1 Seroma, CTCAE PT NCI ctcae5:C58238 Decreased ROM (range of motion) without impaired eating Decreased ROM (range of motion) without impaired eating Grade 1 Trismus Grade 1 Trismus, CTCAE 10044684 C58238 Grade 1 Trismus Grade 1 Trismus Decreased ROM (range of motion) without impaired eating NCI Decreased ROM (range of motion) without impaired eating CTCAE_v5 Grade 1 Trismus PT CTCAE_v5 Grade 1 Trismus, CTCAE PT NCI ctcae5:C58246 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Exostosis Grade 2 Exostosis, CTCAE 10015688 C58246 Grade 2 Exostosis Grade 2 Exostosis Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Exostosis PT CTCAE_v5 Grade 2 Exostosis, CTCAE PT NCI ctcae5:C58251 Symptomatic but non-displaced; immobilization indicated Symptomatic but non-displaced; immobilization indicated Grade 2 Fracture Grade 2 Fracture, CTCAE 10017076 C58251 Grade 2 Fracture Grade 2 Fracture Symptomatic but non-displaced; immobilization indicated NCI Symptomatic but non-displaced; immobilization indicated CTCAE_v5 Grade 2 Fracture PT CTCAE_v5 Grade 2 Fracture, CTCAE PT NCI ctcae5:C58252 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Head Soft Tissue Necrosis, CTCAE Grade 2 Head soft tissue necrosis 10065779 C58252 Grade 2 Head soft tissue necrosis Grade 2 Head soft tissue necrosis Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Head Soft Tissue Necrosis, CTCAE PT NCI Grade 2 Head soft tissue necrosis PT CTCAE_v5 ctcae5:C58253 Symptomatic; limiting instrumental ADL Symptomatic; limiting instrumental ADL Grade 2 Joint Effusion, CTCAE Grade 2 Joint effusion 10023215 C58253 Grade 2 Joint effusion Grade 2 Joint effusion Symptomatic; limiting instrumental ADL NCI Symptomatic; limiting instrumental ADL CTCAE_v5 Grade 2 Joint Effusion, CTCAE PT NCI Grade 2 Joint effusion PT CTCAE_v5 ctcae5:C58262 Moderate pain associated with weakness; pain limiting instrumental ADL Moderate pain associated with weakness; pain limiting instrumental ADL Grade 2 Myositis Grade 2 Myositis, CTCAE 10028653 C58262 Grade 2 Myositis Grade 2 Myositis Moderate pain associated with weakness; pain limiting instrumental ADL NCI Moderate pain associated with weakness; pain limiting instrumental ADL CTCAE_v5 Grade 2 Myositis PT CTCAE_v5 Grade 2 Myositis, CTCAE PT NCI ctcae5:C58263 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Neck Soft Tissue Necrosis, CTCAE Grade 2 Neck soft tissue necrosis 10065781 C58263 Grade 2 Neck soft tissue necrosis Grade 2 Neck soft tissue necrosis Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Neck Soft Tissue Necrosis, CTCAE PT NCI Grade 2 Neck soft tissue necrosis PT CTCAE_v5 ctcae5:C58266 Adult: BMD t-score < -2.5; loss of height <2 cm; therapy to improve BMD indicated; limiting instrumental ADL; Pediatric: Low BMD (z-score <= -2.0) and significant fracture history (defined as a long bone fracture of the lower extremity, vertebral compression, 2 or more long bone fractures of the upper extremities); therapy to improve BMD indicated Adult: BMD t-score < -2.5; loss of height <2 cm; therapy to improve BMD indicated; limiting instrumental ADL; Pediatric: Low BMD (z-score <= -2.0) and significant fracture history (defined as a long bone fracture of the lower extremity, vertebral compression, 2 or more long bone fractures of the upper extremities); therapy to improve BMD indicated Grade 2 Osteoporosis Grade 2 Osteoporosis, CTCAE 10031282 C58266 Grade 2 Osteoporosis Grade 2 Osteoporosis Adult: BMD t-score < -2.5; loss of height <2 cm; therapy to improve BMD indicated; limiting instrumental ADL; Pediatric: Low BMD (z-score <= -2.0) and significant fracture history (defined as a long bone fracture of the lower extremity, vertebral compression, 2 or more long bone fractures of the upper extremities); therapy to improve BMD indicated NCI Adult: BMD t-score < -2.5; loss of height <2 cm; therapy to improve BMD indicated; limiting instrumental ADL; Pediatric: Low BMD (z-score <= -2.0) and significant fracture history (defined as a long bone fracture of the lower extremity, vertebral compression, 2 or more long bone fractures of the upper extremities); therapy to improve BMD indicated CTCAE_v5 Grade 2 Osteoporosis PT CTCAE_v5 Grade 2 Osteoporosis, CTCAE PT NCI ctcae5:C58269 Local wound care; medical intervention indicated (e.g., dressings or topical medications) Local wound care; medical intervention indicated (e.g., dressings or topical medications) Grade 2 Pelvic Soft Tissue Necrosis, CTCAE Grade 2 Pelvic soft tissue necrosis 10065793 C58269 Grade 2 Pelvic soft tissue necrosis Grade 2 Pelvic soft tissue necrosis Local wound care; medical intervention indicated (e.g., dressings or topical medications) NCI Local wound care; medical intervention indicated (e.g., dressings or topical medications) CTCAE_v5 Grade 2 Pelvic Soft Tissue Necrosis, CTCAE PT NCI Grade 2 Pelvic soft tissue necrosis PT CTCAE_v5 ctcae5:C58271 Symptomatic; simple aspiration indicated Symptomatic; simple aspiration indicated Grade 2 Seroma Grade 2 Seroma, CTCAE 10040102 C58271 Grade 2 Seroma Grade 2 Seroma Symptomatic; simple aspiration indicated NCI Symptomatic; simple aspiration indicated CTCAE_v5 Grade 2 Seroma PT CTCAE_v5 Grade 2 Seroma, CTCAE PT NCI ctcae5:C58274 Decreased ROM requiring small bites, soft foods or purees Decreased ROM requiring small bites, soft foods or purees Grade 2 Trismus Grade 2 Trismus, CTCAE 10044684 C58274 Grade 2 Trismus Grade 2 Trismus Decreased ROM requiring small bites, soft foods or purees NCI Decreased ROM requiring small bites, soft foods or purees CTCAE_v5 Grade 2 Trismus PT CTCAE_v5 Grade 2 Trismus, CTCAE PT NCI ctcae5:C58283 Severe symptoms; limiting self care ADL; elective operative intervention indicated Severe symptoms; limiting self care ADL; elective operative intervention indicated Grade 3 Exostosis Grade 3 Exostosis, CTCAE 10015688 C58283 Grade 3 Exostosis Grade 3 Exostosis Severe symptoms; limiting self care ADL; elective operative intervention indicated NCI Severe symptoms; limiting self care ADL; elective operative intervention indicated CTCAE_v5 Grade 3 Exostosis PT CTCAE_v5 Grade 3 Exostosis, CTCAE PT NCI ctcae5:C58288 Severe symptoms; displaced or open wound with bone exposure; limiting self care ADL; operative intervention indicated Severe symptoms; displaced or open wound with bone exposure; limiting self care ADL; operative intervention indicated Grade 3 Fracture Grade 3 Fracture, CTCAE 10017076 C58288 Grade 3 Fracture Grade 3 Fracture Severe symptoms; displaced or open wound with bone exposure; limiting self care ADL; operative intervention indicated NCI Severe symptoms; displaced or open wound with bone exposure; limiting self care ADL; operative intervention indicated CTCAE_v5 Grade 3 Fracture PT CTCAE_v5 Grade 3 Fracture, CTCAE PT NCI ctcae5:C58289 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Head Soft Tissue Necrosis, CTCAE Grade 3 Head soft tissue necrosis 10065779 C58289 Grade 3 Head soft tissue necrosis Grade 3 Head soft tissue necrosis Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Head Soft Tissue Necrosis, CTCAE PT NCI Grade 3 Head soft tissue necrosis PT CTCAE_v5 ctcae5:C58290 Severe symptoms; limiting self care ADL; invasive intervention indicated Severe symptoms; limiting self care ADL; invasive intervention indicated Grade 3 Joint Effusion, CTCAE Grade 3 Joint effusion 10023215 C58290 Grade 3 Joint effusion Grade 3 Joint effusion Severe symptoms; limiting self care ADL; invasive intervention indicated NCI Severe symptoms; limiting self care ADL; invasive intervention indicated CTCAE_v5 Grade 3 Joint Effusion, CTCAE PT NCI Grade 3 Joint effusion PT CTCAE_v5 ctcae5:C58299 Pain associated with severe weakness; limiting self care ADL Pain associated with severe weakness; limiting self care ADL Grade 3 Myositis Grade 3 Myositis, CTCAE 10028653 C58299 Grade 3 Myositis Grade 3 Myositis Pain associated with severe weakness; limiting self care ADL NCI Pain associated with severe weakness; limiting self care ADL CTCAE_v5 Grade 3 Myositis PT CTCAE_v5 Grade 3 Myositis, CTCAE PT NCI ctcae5:C58300 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Neck Soft Tissue Necrosis, CTCAE Grade 3 Neck soft tissue necrosis 10065781 C58300 Grade 3 Neck soft tissue necrosis Grade 3 Neck soft tissue necrosis Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Neck Soft Tissue Necrosis, CTCAE PT NCI Grade 3 Neck soft tissue necrosis PT CTCAE_v5 ctcae5:C58303 Adult: Loss of height >=2 cm; hospitalization indicated; limiting self care ADL; Pediatric: Limiting self care ADL Adult: Loss of height >=2 cm; hospitalization indicated; limiting self care ADL; Pediatric: Limiting self care ADL Grade 3 Osteoporosis Grade 3 Osteoporosis, CTCAE 10031282 C58303 Grade 3 Osteoporosis Grade 3 Osteoporosis Adult: Loss of height >=2 cm; hospitalization indicated; limiting self care ADL; Pediatric: Limiting self care ADL NCI Adult: Loss of height >=2 cm; hospitalization indicated; limiting self care ADL; Pediatric: Limiting self care ADL CTCAE_v5 Grade 3 Osteoporosis PT CTCAE_v5 Grade 3 Osteoporosis, CTCAE PT NCI ctcae5:C58306 Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) Grade 3 Pelvic Soft Tissue Necrosis, CTCAE Grade 3 Pelvic soft tissue necrosis 10065793 C58306 Grade 3 Pelvic soft tissue necrosis Grade 3 Pelvic soft tissue necrosis Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) NCI Operative debridement or other invasive intervention indicated (e.g., tissue reconstruction, flap, or grafting) CTCAE_v5 Grade 3 Pelvic Soft Tissue Necrosis, CTCAE PT NCI Grade 3 Pelvic soft tissue necrosis PT CTCAE_v5 ctcae5:C58308 Symptomatic, elective invasive intervention indicated Symptomatic, elective invasive intervention indicated Grade 3 Seroma Grade 3 Seroma, CTCAE 10040102 C58308 Grade 3 Seroma Grade 3 Seroma Symptomatic, elective invasive intervention indicated NCI Symptomatic, elective invasive intervention indicated CTCAE_v5 Grade 3 Seroma PT CTCAE_v5 Grade 3 Seroma, CTCAE PT NCI ctcae5:C58311 Decreased ROM with inability to adequately aliment or hydrate orally Decreased ROM with inability to adequately aliment or hydrate orally Grade 3 Trismus Grade 3 Trismus, CTCAE 10044684 C58311 Grade 3 Trismus Grade 3 Trismus Decreased ROM with inability to adequately aliment or hydrate orally NCI Decreased ROM with inability to adequately aliment or hydrate orally CTCAE_v5 Grade 3 Trismus PT CTCAE_v5 Grade 3 Trismus, CTCAE PT NCI ctcae5:C58323 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Fracture Grade 4 Fracture, CTCAE 10017076 C58323 Grade 4 Fracture Grade 4 Fracture Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Fracture PT CTCAE_v5 Grade 4 Fracture, CTCAE PT NCI ctcae5:C58324 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Head Soft Tissue Necrosis, CTCAE Grade 4 Head soft tissue necrosis 10065779 C58324 Grade 4 Head soft tissue necrosis Grade 4 Head soft tissue necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Head Soft Tissue Necrosis, CTCAE PT NCI Grade 4 Head soft tissue necrosis PT CTCAE_v5 ctcae5:C58333 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Myositis Grade 4 Myositis, CTCAE 10028653 C58333 Grade 4 Myositis Grade 4 Myositis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Myositis PT CTCAE_v5 Grade 4 Myositis, CTCAE PT NCI ctcae5:C58334 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Neck Soft Tissue Necrosis, CTCAE Grade 4 Neck soft tissue necrosis 10065781 C58334 Grade 4 Neck soft tissue necrosis Grade 4 Neck soft tissue necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Neck Soft Tissue Necrosis, CTCAE PT NCI Grade 4 Neck soft tissue necrosis PT CTCAE_v5 ctcae5:C58340 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Pelvic Soft Tissue Necrosis, CTCAE Grade 4 Pelvic soft tissue necrosis 10065793 C58340 Grade 4 Pelvic soft tissue necrosis Grade 4 Pelvic soft tissue necrosis Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Pelvic Soft Tissue Necrosis, CTCAE PT NCI Grade 4 Pelvic soft tissue necrosis PT CTCAE_v5 ctcae5:C58355 Death Death Grade 5 Fracture Grade 5 Fracture, CTCAE 10017076 C58355 Grade 5 Fracture Grade 5 Fracture Death NCI Death CTCAE_v5 Grade 5 Fracture PT CTCAE_v5 Grade 5 Fracture, CTCAE PT NCI ctcae5:C58356 Death Death Grade 5 Head Soft Tissue Necrosis, CTCAE Grade 5 Head soft tissue necrosis 10065779 C58356 Grade 5 Head soft tissue necrosis Grade 5 Head soft tissue necrosis Death NCI Death CTCAE_v5 Grade 5 Head Soft Tissue Necrosis, CTCAE PT NCI Grade 5 Head soft tissue necrosis PT CTCAE_v5 ctcae5:C58363 Death Death Grade 5 Neck Soft Tissue Necrosis, CTCAE Grade 5 Neck soft tissue necrosis 10065781 C58363 Grade 5 Neck soft tissue necrosis Grade 5 Neck soft tissue necrosis Death NCI Death CTCAE_v5 Grade 5 Neck Soft Tissue Necrosis, CTCAE PT NCI Grade 5 Neck soft tissue necrosis PT CTCAE_v5 ctcae5:C58369 Death Death Grade 5 Pelvic Soft Tissue Necrosis, CTCAE Grade 5 Pelvic soft tissue necrosis 10065793 C58369 Grade 5 Pelvic soft tissue necrosis Grade 5 Pelvic soft tissue necrosis Death NCI Death CTCAE_v5 Grade 5 Pelvic Soft Tissue Necrosis, CTCAE PT NCI Grade 5 Pelvic soft tissue necrosis PT CTCAE_v5 ctcae5:C58382 A finding of traumatic injury to the bone in which the continuity of the bone is broken. A finding of traumatic injury to the bone in which the continuity of the bone is broken. Fracture Fracture, CTCAE 10017076 C58382 Fracture Fracture A finding of traumatic injury to the bone in which the continuity of the bone is broken. NCI A finding of traumatic injury to the bone in which the continuity of the bone is broken. CTCAE_v5 Fracture PT CTCAE_v5 Fracture, CTCAE PT NCI ctcae5:C58383 A disorder characterized by a necrotic process occurring in the soft tissues of the head. A disorder characterized by a necrotic process occurring in the soft tissues of the head. Head Soft Tissue Necrosis, CTCAE Head soft tissue necrosis 10065779 C58383 Head soft tissue necrosis Head soft tissue necrosis A disorder characterized by a necrotic process occurring in the soft tissues of the head. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the head. CTCAE_v5 Head Soft Tissue Necrosis, CTCAE PT NCI Head soft tissue necrosis PT CTCAE_v5 ctcae5:C58394 A disorder characterized by a necrotic process occurring in the soft tissues of the neck. A disorder characterized by a necrotic process occurring in the soft tissues of the neck. Neck Soft Tissue Necrosis, CTCAE Neck soft tissue necrosis 10065781 C58394 Neck soft tissue necrosis Neck soft tissue necrosis A disorder characterized by a necrotic process occurring in the soft tissues of the neck. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the neck. CTCAE_v5 Neck Soft Tissue Necrosis, CTCAE PT NCI Neck soft tissue necrosis PT CTCAE_v5 ctcae5:C58399 A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. Pelvic Soft Tissue Necrosis, CTCAE Pelvic soft tissue necrosis 10065793 C58399 Pelvic soft tissue necrosis Pelvic soft tissue necrosis A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. NCI A disorder characterized by a necrotic process occurring in the soft tissues of the pelvis. CTCAE_v5 Pelvic Soft Tissue Necrosis, CTCAE PT NCI Pelvic soft tissue necrosis PT CTCAE_v5 ctcae5:C58401 A finding of tumor-like collection of serum in the tissues. A finding of tumor-like collection of serum in the tissues. Seroma Seroma, CTCAE 10040102 C58401 Seroma Seroma A finding of tumor-like collection of serum in the tissues. NCI A finding of tumor-like collection of serum in the tissues. CTCAE_v5 Seroma PT CTCAE_v5 Seroma, CTCAE PT NCI ctcae5:C58404 A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. Trismus Trismus, CTCAE 10044684 C58404 Trismus Trismus A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. NCI A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of the muscles of mastication. CTCAE_v5 Trismus PT CTCAE_v5 Trismus, CTCAE PT NCI ctcae5:C59479 ANC <1000/mm3 with a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour ANC <1000/mm3 with a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour Grade 3 Febrile Neutropenia, CTCAE Grade 3 Febrile neutropenia 10016288 C59479 Grade 3 Febrile neutropenia Grade 3 Febrile neutropenia ANC <1000/mm3 with a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour NCI ANC <1000/mm3 with a single temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour CTCAE_v5 Grade 3 Febrile Neutropenia, CTCAE PT NCI Grade 3 Febrile neutropenia PT CTCAE_v5 ctcae5:C59715 Life-threatening consequences; urgent intervention indicated Life-threatening consequences; urgent intervention indicated Grade 4 Febrile Neutropenia, CTCAE Grade 4 Febrile neutropenia 10016288 C59715 Grade 4 Febrile neutropenia Grade 4 Febrile neutropenia Life-threatening consequences; urgent intervention indicated NCI Life-threatening consequences; urgent intervention indicated CTCAE_v5 Grade 4 Febrile Neutropenia, CTCAE PT NCI Grade 4 Febrile neutropenia PT CTCAE_v5 ctcae5:C59951 Death Death Grade 5 Febrile Neutropenia, CTCAE Grade 5 Febrile neutropenia 10016288 C59951 Grade 5 Febrile neutropenia Grade 5 Febrile neutropenia Death NCI Death CTCAE_v5 Grade 5 Febrile Neutropenia, CTCAE PT NCI Grade 5 Febrile neutropenia PT CTCAE_v5