1.2 has_obo_format_version LDA ICD10:http://purl.bioontology.org/ontology/ICD10CM/E71.52 MESH:http://purl.bioontology.org/ontology/MESH/D000326 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10588 Adrenoleukodystrophy Adrenoleukodystrophy Adrenoleukodystrophy ALEX MESH:http://purl.bioontology.org/ontology/MESH/D038261 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_4252 Alexanders_Disease Alexander's Disease Alexanders_Disease Group of neurodegenerative disorders in which the main pathological observation is abnormal accumulation of alpha-synuclein. Alpha-Synucleinopathy_Disorders true Alpha-Synucleinopathy Disorders Alpha-Synucleinopathy_Disorders AD ICD10:http://purl.bioontology.org/ontology/ICD10/G30 MESH:http://purl.bioontology.org/ontology/MESH/D000544 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002511 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10652 Alzheimers_Disease true Alzheimer's Disease Alzheimers_Disease ALS ICD10:http://purl.bioontology.org/ontology/ICD10CM/G12.21 MESH:http://purl.bioontology.org/ontology/MESH/D000690 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007354 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_332 Amyotrophic_Lateral_Sclerosis true Amyotrophic Lateral Sclerosis Amyotrophic_Lateral_Sclerosis AGD SNOMEDCT: http://purl.bioontology.org/ontology/SNOMEDCT/230281007 Argyrophilic_Grain_Disease Argyrophilic Grain Disease Argyrophilic_Grain_Disease ADHD ICD10:http://purl.bioontology.org/ontology/ICD10CM/F90 MESH:http://purl.bioontology.org/ontology/MESH/D001289 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007018 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1094 Attention_Deficit_Hyperactivity_Disorder Attention Deficit Hyperactivity Disorder Attention_Deficit_Hyperactivity_Disorder Patient's who have an alphasynucleinopathy or so called "Lewy body disease", however, they do not have the typical neuropathological picture of PD. In these cases additional neuropathological findings are considered to contribute to the clinical picture. These additional neuropathological findings vary between cases. Hence the "atypical Parkinson's disease" ATPD Atypical_Parkinsons_Disease true Atypical Parkinson's Disease Atypical_Parkinsons_Disease ASD ICD10:http://purl.bioontology.org/ontology/ICD10/F84.0, http://purl.bioontology.org/ontology/ICD10/F84.1, http://purl.bioontology.org/ontology/ICD10/F84.5 MESH:http://purl.bioontology.org/ontology/MESH/D000067877 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000717 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060041 Autism_Spectrum_Disorder Autism Spectrum Disorder Autism_Spectrum_Disorder ADCA Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0001251 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_1441 Autosomal_Dominant_Cerebellar_Ataxia true Autosomal Dominant Cerebellar Ataxia Autosomal_Dominant_Cerebellar_Ataxia BINSW MESH:http://purl.bioontology.org/ontology/MESH/D015140 Binswangers_Disease true Binswanger's Disease Binswangers_Disease BP ICD10:http://purl.bioontology.org/ontology/ICD10CM/F31 MESH:http://purl.bioontology.org/ontology/MESH/D001714 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007302 Bipolar_Disorder Bipolar Disorder Bipolar_Disorder Category including neoplasms of the brain, both primary (benign/malignant) and secondary (metastatic) forms. Brain_Cancer Brain Cancer Brain_Cancer Donors with C9ORF72 mutation mostly show FTD-TDP-B pathology, but FTD-TDP A is also seen. C9ORF72 MESH: http://purl.bioontology.org/ontology/MESH/D016657 C9ORF72 C9ORF72 C9ORF72 Group of disorders in which the main symptom is ataxia. ATAXIA ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11 MESH: http://purl.bioontology.org/ontology/MESH/D002524 Human phenotype ontology: http://purl.obolibrary.org/obo/HP_0001251 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050753 Cerebellar_Ataxia true Cerebellar Ataxia Cerebellar_Ataxia VDCAD ICD10:http://purl.bioontology.org/ontology/ICD10CM/I67.850 MESH:http://purl.bioontology.org/ontology/MESH/D046589 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_13945 Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy Cerebral_Autosomal_Dominant_Arteriopathy_with_Sub-cortical_Infarcts_and_Leukoencephalopathy true CADASIL Cerebral_Autosomal_Dominant_Arteriopathy_with_Sub-cortical_Infarcts_and_Leukoencephalopathy CVA MESH: http://purl.bioontology.org/ontology/MESH/D020521 DOID: http://purl.obolibrary.org/obo/DOID_6713 Cerebrovascular_Accident Cerebrovascular Accident Cerebrovascular_Accident CA MESH:http://purl.bioontology.org/ontology/MESH/D016657 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_9246 cerebral amyloid angiopathy Congophilic_Angiopathy Congophilic Angiopathy Congophilic_Angiopathy Donors without cognitive decline or dementia, who neuropathologically do not meet the criteria for any neurodegenerative disease. CON Control_Brain Control Brain Control_Brain CBD ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.85 Corticobasal_Degeneration true Corticobasal Degeneration Corticobasal_Degeneration CJD ICD10:http://purl.bioontology.org/ontology/ICD10/A81.0 MESH:http://purl.bioontology.org/ontology/MESH/D007562 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11949 Creutzfeldt-Jakob_Disease true Creutzfeldt-Jakob Disease Creutzfeldt-Jakob_Disease DEM MESH:http://purl.bioontology.org/ontology/MESH/D003704 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000726 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1307 Dementia true Dementia Dementia DLB MESH: http://purl.bioontology.org/ontology/MESH/D020961 Human Disease Ontology: https://disease-ontology.org/?id=DOID:12217 Dementia_with_Lewy_Bodies true Dementia with Lewy Bodies Dementia_with_Lewy_Bodies DEV MESH:http://purl.bioontology.org/ontology/MESH/D002658 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0012759 Developmental_Diseases Developmental Diseases Developmental_Diseases DAI ICD10:http://purl.bioontology.org/ontology/ICD10/S06.2, http://purl.bioontology.org/ontology/ICD10/S06 MESH:http://purl.bioontology.org/ontology/MESH/D020833 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0003405 Diffuse_Axonal_Injury Diffuse Axonal Injury Diffuse_Axonal_Injury DOWN ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q90 MESH:http://purl.bioontology.org/ontology/MESH/D004314 Downs_Syndrome Down's Syndrome Downs_Syndrome DYSTO ICD10: http://purl.bioontology.org/ontology/ICD10CM/G24 MESH: http://purl.bioontology.org/ontology/MESH/D004421 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0001332 Dystonia Dystonia Dystonia ENCE ICD10:http://purl.bioontology.org/ontology/ICD10CM/G04.9 MESH:http://purl.bioontology.org/ontology/MESH/D004660 Encephalitis Encephalitis Encephalitis Group of pathologic disorders that affect the brain, which cannot be more appropriately included in another category/group. ENCEPHA Human phenotype ontology: http://purl.obolibrary.org/obo/HP_0001298 Encephalopathy Encephalopathy Encephalopathy EPI ICD10:http://purl.bioontology.org/ontology/ICD10/G40 MESH:http://purl.bioontology.org/ontology/MESH/D004827 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0001250 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1826 Epilepsy Epilepsy Epilepsy FAHR MESH:http://purl.bioontology.org/ontology/MESH/C536275 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002135 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060230 Fahrs_Syndrome true Fahr's Syndrome Fahrs_Syndrome FRAGX ICD10: http://purl.bioontology.org/ontology/ICD10CM/Q99.2 MESH: http://purl.bioontology.org/ontology/MESH/D005600 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_14261 Fragile_X_Syndrome Fragile X Syndrome Fragile_X_Syndrome FA ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11.11 Friedreichs_Ataxia true Friedreich's Ataxia Friedreichs_Ataxia FTD ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.0 MESH:http://purl.bioontology.org/ontology/MESH/D057174 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002145 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_9255 Frontotemporal_Dementia true Frontotemporal Dementia Frontotemporal_Dementia Frontoterporal lobe degeneration with FUS (Fused in sarcoma) accumulations. FTD-FUS Frontotemporal_Dementia_FUS true Frontotemporal Dementia FUS Frontotemporal_Dementia_FUS Donors with frontotomporal lobe degeneration with TDP-43 pathology. FTD-TDP https://pubmed.ncbi.nlm.nih.gov/21644037/ Frontotemporal_Dementia_TDP true Frontotemporal Dementia TDP Frontotemporal_Dementia_TDP Donors belonging to the category "Frontotemporal Dementia TDP Undefined" are known to have FTD-TDP. However, the subtype (A, B, or C) could not be distinguished. FTD-TDP_undefined Frontotemporal_Dementia_TDP_Undefined true Frontotemporal Dementia TDP Undefined Frontotemporal_Dementia_TDP_Undefined FTD with TDP-43 pathology, charactarized by numerous short dystrophic neurites and crescentic or oval neuronal cytoplasmatic inclusions, concentrated primarely in neocortical layer II. FTD-TDP-A Frontotemporal_Dementia_TDP_type_A true Frontotemporal Dementia TDP type A Frontotemporal_Dementia_TDP_type_A FTD with TDP-43 pathology, charactarized by a moderate numbers of neuronal cytoplasmatic inclusions, in all cortical layers, but with only few dystrophic neurites. FTD-TDP-B Frontotemporal_Dementia_TDP_type_B true Frontotemporal Dementia TDP type B Frontotemporal_Dementia_TDP_type_B FTD with TDP-43 pathology, characterized by a predominance of elongated dystrophic neurites in upper cortical layers with only few neuronal cytoplasmatic inclusions. FTD-TDP-C Frontotemporal_Dementia_TDP_type_C true Frontotemporal Dementia TDP type C Frontotemporal_Dementia_TDP_type_C Donors with FTD characterized by abnormal intracellular accumulation of hyperphosphorilated tau. FTD-TAU https://pubmed.ncbi.nlm.nih.gov/27306735/ Frontotemporal_Dementia_Tauopathy true Frontotemporal Dementia Tauopathy Frontotemporal_Dementia_Tauopathy Donors with frontotemporal lobar degeneration with ubiquitin or P62 only immunoreactive inclusions (negative for all other proteins, as well as cases that have not yet been analyzed with FUS or TDP-43) FTD-UPS https://pubmed.ncbi.nlm.nih.gov/21810890/ Frontotemporal_Dementia_Ubiquitine true Frontotemporal Dementia Ubiquitine Frontotemporal_Dementia_Ubiquitine Donors belonging to the category "Frontotemporal Dementia Undefined" are known to have FTD. However, the subtype could not be distinguished. FTD_undefined Frontotemporal_Dementia_Undefined true Frontotemporal Dementia Undefined Frontotemporal_Dementia_Undefined GUIL ICD10:http://purl.bioontology.org/ontology/ICD10/G61.0 MESH:http://purl.bioontology.org/ontology/MESH/D020275 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_12842 Guillain-Barre_Disease Guillain-Barré Disease Guillain-Barre_Disease HMSN ICD10:http://purl.bioontology.org/ontology/ICD10/G60.0 MESH:http://purl.bioontology.org/ontology/MESH/D015417 Charcot Marie Tooth disease Hereditary_Motoric_Sensoric_Neuropathy Hereditary Motoric Sensoric Neuropathy Hereditary_Motoric_Sensoric_Neuropathy HSP ICD10:http://purl.bioontology.org/ontology/ICD10/G11.4 MESH:http://purl.bioontology.org/ontology/MESH/D015419 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002313 Hereditary_Spastic_Paraplegia Hereditary Spastic Paraplegia Hereditary_Spastic_Paraplegia HIP ICD10:http://purl.bioontology.org/ontology/ICD10CM/G93.81 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0033715 Hippocampal_Sclerosis Hippocampal Sclerosis Hippocampal_Sclerosis HIV ICD10:http://purl.bioontology.org/ontology/ICD10CM/B20-B20 MESH:http://purl.bioontology.org/ontology/MESH/D006678 Human_Immunodeficiency_Virus Human Immunodeficiency Virus Human_Immunodeficiency_Virus HD ICD10:http://purl.bioontology.org/ontology/ICD10CM/G10 MESH:http://purl.bioontology.org/ontology/MESH/D006816 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_12858 Huntingtons_Disease true Huntington's Disease Huntingtons_Disease COHA ICD10:http://purl.bioontology.org/ontology/ICD10/G91 MESH:http://purl.bioontology.org/ontology/MESH/D006849 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000238 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10908 Hydrocephalus_Adultorum Hydrocephalus Adultorum Hydrocephalus_Adultorum Incidental Lewy body disease is the presence of Lewy bodies or Lewy neurites without clinical findings of parkinsonism or dementia. iLBD MESH: http://purl.bioontology.org/ontology/MESH/D016631 Human phenotype ontology: http://purl.obolibrary.org/obo/HP_0100315 PUBMED: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366193/, https://pubmed.ncbi.nlm.nih.gov/20175211/ Incidental_Lewy_Body_Disease true Incidental Lewy Body Disease Incidental_Lewy_Body_Disease IS Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0002637 Ischemic_Changes Ischemic Changes Ischemic_Changes KLIN ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q98.1, http://purl.bioontology.org/ontology/ICD10CM/Q98.0,http://purl.bioontology.org/ontology/ICD10CM/Q98.4 MESH:http://purl.bioontology.org/ontology/MESH/D007713 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1921 Klinefelters_Syndrome Klinefelter's Syndrome Klinefelters_Syndrome KOR ICD10: http://purl.bioontology.org/ontology/ICD10CM/F04 MESH:http://purl.bioontology.org/ontology/MESH/D020915 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10915 Korsakoff_Syndrome true Korsakoff Syndrome Korsakoff_Syndrome LD Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002415 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10579 Leukodystrophy Leukodystrophy Leukodystrophy Donors belonging to the category "Leukodystrophy Other" have Leukodystrophy, but this was not further specified. LD_other Leukodystrophy_Other Leukodystrophy Other Leukodystrophy_Other MDD ICD10: http://purl.bioontology.org/ontology/ICD10CM/F33 MESH:http://purl.bioontology.org/ontology/MESH/D003865 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000716 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1470 Major_Depressive_Disorder Major Depressive Disorder Major_Depressive_Disorder MEN ICD10:http://purl.bioontology.org/ontology/ICD10/G00 MESH:http://purl.bioontology.org/ontology/MESH/D008581 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0001287 Meningitis Meningitis Meningitis MEDIS MESH:http://purl.bioontology.org/ontology/MESH/D008659, http://purl.bioontology.org/ontology/MESH/D001928 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0014667 Metabolic_Disease Metabolic Disease Metabolic_Disease Donors belonging to the category "Motor Neuron Disease Other" have a Motor Neuron Disease which is different from ALS, but not further specified. MND_other Motor_Neuron_Disease_Other true Motor Neuron Disease Other Motor_Neuron_Disease_Other MND ICD10:http://purl.bioontology.org/ontology/ICD10CM/G12.2 MESH:http://purl.bioontology.org/ontology/MESH/D000690 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_231 Motor_Neuron_Diseases true Motor Neuron Diseases Motor_Neuron_Diseases MS ICD10: http://purl.bioontology.org/ontology/ICD10CM/G35 MESH: http://purl.bioontology.org/ontology/MESH/D009103 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_2377 Multiple_Sclerosis Multiple Sclerosis Multiple_Sclerosis MS-PP Human Disease Ontology: https://disease-ontology.org/?id=DOID:0050784 Multiple_Sclerosis_Primary_Progressive Multiple Sclerosis Primary Progressive Multiple_Sclerosis_Primary_Progressive MS-RR Human Disease Ontology: https://disease-ontology.org/?id=DOID:2378 Multiple_Sclerosis_Remitting_Relapsing Multiple Sclerosis Remitting Relapsing Multiple_Sclerosis_Remitting_Relapsing MS-SP Human Disease Ontology: https://disease-ontology.org/?id=DOID:0050783 Multiple_Sclerosis_Secondary_Progressive Multiple Sclerosis Secondary Progressive Multiple_Sclerosis_Secondary_Progressive Donors belonging to the category "Multiple Sclerosis Undefined" are known to have MS. However, the subtype could not be distinguished. MS_undefined Multiple_Sclerosis_undefined Multiple Sclerosis Undefined Multiple_Sclerosis_undefined MSA MESH: http://purl.bioontology.org/ontology/MESH/D019578 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_4752 Multiple_System_Atrophy true Multiple System Atrophy Multiple_System_Atrophy Category including the mutations that occur in donors and that are relevant for understanding their family or clinical history. Mutation Mutation Mutation NARCO ICD10: http://purl.bioontology.org/ontology/ICD10CM/G47.41 MESH: http://purl.bioontology.org/ontology/MESH/D009290 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_8986 Narcolepsy Narcolepsy Narcolepsy Group of disorders characterized by inflammation in the central nervous system. AUTO MESH: http://purl.bioontology.org/ontology/MESH/D020274 Neuroinflammatory_Disease Neuroinflammatory Disease Neuroinflammatory_Disease Category including neurological disorders with various causes (genetic, autoimmune, vascular, infectious). Progressive neurodegenerative disorders form a separate category. Neurological_Disorders Neurological Disorders Neurological_Disorders NMO ICD10: http://purl.bioontology.org/ontology/ICD10CM/G36.0 MESH: http://purl.bioontology.org/ontology/MESH/D009471 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_8869 Neuromyelitis_Optica Neuromyelitis Optica Neuromyelitis_Optica Category including neuropathophysiological traits observed on autopsy. Neuropathophysiological_Traits Neuropathophysiological Traits Neuropathophysiological_Traits Degeneration of the substantia nigra. NIG MESH:http://purl.bioontology.org/ontology/MESH/D013378 Nigral_Degeneration Nigral Degeneration Nigral_Degeneration NCSD ICD10:http://purl.bioontology.org/ontology/ICD10CM/F03.9, http://purl.bioontology.org/ontology/ICD10CM/G31.1 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000726 Non-Classifiable_Senile_Dementia true Non-Classifiable Senile Dementia Non-Classifiable_Senile_Dementia NHL ICD10: http://purl.bioontology.org/ontology/ICD10CM/C85 MESH: http://purl.bioontology.org/ontology/MESH/D008228 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0012539 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060060 Non-Hodgkin_Lymphoma Non-Hodgkin Lymphoma Non-Hodgkin_Lymphoma OCD ICD10:http://purl.bioontology.org/ontology/ICD10CM/F42 MESH:http://purl.bioontology.org/ontology/MESH/D009771 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10933 Obsessive_Compulsive_Disorder Obsessive Compulsive Disorder Obsessive_Compulsive_Disorder Category including disorders that may have implications for nervous system structure and function. Other_Disorders_with_Neurological_Implications Other Disorders with Neurological Implications Other_Disorders_with_Neurological_Implications Pathogenic mutation in Progranulin (GRN) gene on chromosome 17. PROG PROG PROG PROG PAL MESH:http://purl.bioontology.org/ontology/MESH/C564910 Human phenotype ontology: http://purl.obolibrary.org/obo/HP_0007132 Pallidal_Degeneration Pallidal Degeneration Pallidal_Degeneration PD ICD10: http://purl.bioontology.org/ontology/ICD10CM/G20 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_14330 Parkinsons_Disease true Parkinson's Disease Parkinsons_Disease Donors with with clinical and neuropathological PD, and clinical cognitive decline/dementia. PDD Parkinsons_Disease_with_Dementia true Parkinson's Disease with Dementia Parkinsons_Disease_with_Dementia PID ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.01 MESH: http://purl.bioontology.org/ontology/MESH/D020774 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11870 Picks_Disease true Pick's Disease Picks_Disease POLY ICD10:http://purl.bioontology.org/ontology/ICD10CM/G60-G65 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1389 Polyneuropathy Polyneuropathy Polyneuropathy Donors belonging to the category "Polyneuropathy Other" have Polyneuropathy, but this was not further specified. POLY_other Polyneuropathy_Other Polyneuropathy Other Polyneuropathy_Other PTSD ICD10:http://purl.bioontology.org/ontology/ICD10CM/F43.1 MESH:http://purl.bioontology.org/ontology/MESH/D013313 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_2055 Post_Traumatic_Stress_Disorder Post Traumatic Stress Disorder Post_Traumatic_Stress_Disorder PCAD MEDDRA:http://purl.bioontology.org/ontology/MEDDRA/10078207 Posterior_Cortical_Atrophy_Dementia true Posterior Cortical Atrophy Dementia Posterior_Cortical_Atrophy_Dementia PWS ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q87.11 MESH:http://purl.bioontology.org/ontology/MESH/D011218 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11983 Prader-Willi_Syndrome Prader-Willi Syndrome Prader-Willi_Syndrome PML ICD10:http://purl.bioontology.org/ontology/ICD10/A81.2 MESH:http://purl.bioontology.org/ontology/MESH/D007968 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_643 Progressive_Multifocal_Leucoencephalopathy Progressive Multifocal Leucoencephalopathy Progressive_Multifocal_Leucoencephalopathy Category including disorders characterized by progressive dysfunction of the nervous system. Progressive_Neurodegenerative_Diseases Progressive Neurodegenerative Diseases Progressive_Neurodegenerative_Diseases PSP MESH:http://purl.bioontology.org/ontology/MESH/D013494 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_678 Progressive_Supranuclear_Palsy true Progressive Supranuclear Palsy Progressive_Supranuclear_Palsy Category including psychiatric disorders. ICD10: http://purl.bioontology.org/ontology/ICD10CM/F01-F99 MESH: http://purl.bioontology.org/ontology/MESH/D001523 Human disease ontology: https://disease-ontology.org/?id=DOID_150 Psychiatric_Disorders Psychiatric Disorders Psychiatric_Disorders Donors belonging to the category "Psychiatric Disorder Other" have a Psychiatric Disorder, but this was not further specified. PSYCH_other Psychiatric_Other Psychiatric Other Psychiatric_Other Category including disorders that are infrequently observed in the general population and/or the autopsy cohort. Rare_Disorders Rare Disorders Rare_Disorders SCZ ICD10:http://purl.bioontology.org/ontology/ICD10CM/F20 MESH:http://purl.bioontology.org/ontology/MESH/D012559 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_5419 Schizophrenia Schizophrenia Schizophrenia SICC is a term used by the Netherlands Brain Bank since the beginning. At first it was only about the progress of amyloid plagues and neurofibrillary tangles, but not sufficient enough to meet the criteria for Alzheimer’s disease. Over the years, the neuropathological field has developed, and by now SICC encompasses both amyloid plaques (up to Thal phase 3 out of 5) and tangles (Braak 1, 2 and 3), but also ARTAG (age-related tau-astrogliopathy) and mild cerebral amyloid angiopathy. In the present these findings are all written down separately. SICC ARTAG Senile_Involutive_Cortical_Changes Senile Involutive Cortical Changes Senile_Involutive_Cortical_Changes Donors with cerebral septic lesions and/or a cerebral abcess. SEP Septic_Cerebral_Foci Septic Cerebral Foci Septic_Cerebral_Foci SCA ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11 MESH: http://purl.bioontology.org/ontology/MESH/D020754 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050753 Spinocerebellar_Ataxia true Spinocerebellar Ataxia Spinocerebellar_Ataxia Group of rare syndromes associated with a specific genetic cause. Syndromes Syndromes Syndromes TAU MESH:http://purl.bioontology.org/ontology/MESH/D024801 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_680 Tauopathy Tauopathy Tauopathy VD ICD10: http://purl.bioontology.org/ontology/ICD10CM/F01 MESH: http://purl.bioontology.org/ontology/MESH/D015140 DOID: https://disease-ontology.org/?id=DOID:8725 Vascular_Dementia Vascular Dementia Vascular_Dementia Donors with neuropathological vascular lesions (infarctions/atherosclerosis/hemmorhages). VE Vascular_Encephalopathy Vascular Encephalopathy Vascular_Encephalopathy Group of traits observed on autopsy related to vascular pathology. Vascular_Pathology Vascular Pathology Vascular_Pathology WER ICD10:http://purl.bioontology.org/ontology/ICD10CM/E51.2 MESH:http://purl.bioontology.org/ontology/MESH/D014899 Human disease ontology: http://purl.obolibrary.org/obo/DOID_2384 Wernicke_Encephalopathy Wernicke Encephalopathy Wernicke_Encephalopathy FXTAS MESH: http://purl.bioontology.org/ontology/MESH/C564105 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050879 Fragile-X-Associated_Tremor/Ataxia_Syndrome true Fragile-X-Associated Tremor/Ataxia Syndrome Fragile-X-Associated_Tremor/Ataxia_Syndrome TUM ICD10: http://purl.bioontology.org/ontology/ICD10CM/R90.0 MESH: http://purl.bioontology.org/ontology/MESH/D001932 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0030692 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1319 Space-Occupying_Proces/Tumor Space-Occupying Proces or Tumor Space-Occupying_Proces/Tumor EXCLUDE EXCLUDE EXCLUDE EXCLUDE NPA No_PA-report_available No PA-report available No_PA-report_available NAD Non-Alzheimer_dementia Non-Alzheimer dementia Non-Alzheimer_dementia Unknown Unknown_Diagnosis Unknown Diagnosis Unknown_Diagnosis NU Tissue_is_not_usable_or_diagnosis_is_other_than_described_in_list_or_diagnosis is_unknown Tissue is not usable, or diagnosis is other than described in list, or diagnosis is unknown Tissue_is_not_usable_or_diagnosis_is_other_than_described_in_list_or_diagnosis is_unknown Alexander%2525252527s_disease Fahr%2525252527s_syndrome Huntington%2525252527s_disease Picks_disease 1.2