Alan Ruttenberg Andrew Spear Michaela Guendel Pierre Grenon Ashutosh Erfan Younesi Holger Stenzhorn Michaela Guendel Satoshi Mizuno 12.9.11 20.02.12 application/rdf+xml http://www.ifomis.org/bfo/1.1 en Institute for Formal Ontology and Medical Information Science (IFOMIS) http://creativecommons.org/licenses/by/3.0 Barry Smith and Pierre Grenon: "The Cornucopia of Formal Ontological Relations" Barry Smith: "Against Fantology" Barry Smith: "Basic Tools of Formal Ontology" Barry Smith: "Beyond Concepts: Ontology as Reality Representation" Pierre Grenon and Barry Smith: "SNAP and SPAN: Towards Geospatial Dynamics" Pierre Grenon, Barry Smith and Louis Goldberg: "Biodynamic Ontology: Applying BFO in the Biomedical Domain" Pierre Grenon: "BFO in a Nutshell: A Bi-categorial Axiomatization of BFO and Comparison with DOLCE" Pierre Grenon: "Nuts in BFO's Nutshell: Revisions to the Bi-categorial Axiomatization of BFO" Pierre Grenon: "Spatio-temporality in Basic Formal Ontology: SNAP and SPAN, Upper-Level Ontology, and Framework for Formalization" Basic Formal Ontology (BFO) Alzheimer Ontology proposed upper view ontology for neurodegenerative diseases v0.1 v14 1.1.1 v0.2 v15 Heneka comments / shifs / modifications integrated OBO_REL:adjacent_to Note that adjacent_to as thus defined is not a symmetric relation, in contrast to its instance-level counterpart. For it can be the case that Cs are in general such as to be adjacent to instances of C1 while no analogous statement holds for C1s in general in relation to instances of C. Examples are: nuclear membrane adjacent_to cytoplasm; seminal vesicle adjacent_to urinary bladder; ovary adjacent_to parietal pelvic peritoneum C adjacent to C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c and c' are in spatial proximity OBO_REL:bearer_of This relation links a bearer to its qualities, functions, dispositions and other dependent continuants. comment: Examples: red eye bearer_of redness ! range: snap:DependentContinuant A relation between an entity and a dependent continuant; the reciprocal relation of inheres_in OBO_REL:derives_from Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant. Derivation on the instance level (*derives_from*) holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. We say that one class C derives_from class C' if instances of C are connected to instances of C' via some chain of instance-level derivation relations. Example: osteocyte derives_from osteoblast. Formally: C derives_immediately_from C' if and only if: given any c and any t, if c instantiates C at time t, then there is some c' and some t', such that c' instantiates C' at t' and t' earlier-than t and c *derives_from* c'. C derives_from C' if and only if: there is an chain of immediate derivation relations connecting C to C'. OBO_REL:has_agent As for has_participant, but with the additional condition that the component instance is causally active in the relevant process OBO_REL:has_participant Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. P has_participant C if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t OBO_REL:has_role A relation between a continuant C and a role R. The reciprocal relation of role_of. has role This relation links qualities, functions, dispositions and other dependent continuants to their bearers. Examples: A particular shape that inheres in a lung; The redness that ineres in a Drosophila eye; Catalytic activity function inheres_in catalytic molecule. Note that inherence is a functional relation: if x inheres_in y at t and x inheres_in z at t, then y=z. We leave open the possibility of a relation multiply_inheres_in, such as between a gene sequence and the multiple chromosomes it multiply inheres in. The super-relation of both inheres_in and multiply_inheres_in would be depends_on A relation between a dependent continuant D and an entity E. D inheres_in E iff: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation." [GOC:cjm] Used to generate the various views on the ontology. An entity can be used in a specific context. OBO_REL:located_in Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus C located_in C' if and only if: given any c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c *located_in* c'. (Here *located_in* is the instance-level location relation.) OBO_REL:part_of Parthood as a relation between instances: The primitive instance-level relation p part_of p1 is illustrated in assertions such as: this instance of rhodopsin mediated phototransduction part_of this instance of visual perception. This relation satisfies at least the following standard axioms of mereology: reflexivity (for all p, p part_of p); anti-symmetry (for all p, p1, if p part_of p1 and p1 part_of p then p and p1 are identical); and transitivity (for all p, p1, p2, if p part_of p1 and p1 part_of p2, then p part_of p2). Analogous axioms hold also for parthood as a relation between spatial regions. For parthood as a relation between continuants, these axioms need to be modified to take account of the incorporation of a temporal argument. Thus for example the axiom of transitivity for continuants will assert that if c part_of c1 at t and c1 part_of c2 at t, then also c part_of c2 at t. Parthood as a relation between classes: To define part_of as a relation between classes we again need to distinguish the two cases of continuants and processes, even though the explicit reference to instants of time now falls away. For continuants, we have C part_of C1 if and only if any instance of C at any time is an instance-level part of some instance of C1 at that time, as for example in: cell nucleus part_ of cell. For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.) OBO_REL:preceded_by An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. P preceded_by P' if and only if: given any process p that instantiates P at a time t, there is some process p' such that p' instantiates P' at time t', and t' is earlier than t. NDDUO:Age AAO age at onset age-at-onset Age NDDUO:Age_adjusted_mortality_rate Age adjusted mortality rates Age adjusted mortality rate NDDUO:Age_period_cohort_analysis Age period cohort analysis NDDUO:Age_specific_mortality_rate Age specific mortality rates Age specific mortality rate NDDUO:Age_standardized_mortality_rate Age standardized mortality rates Age standardized mortality rate NDDUO:Analytical_study Analytical studies Analytical study NDDUO:Anatomical Anatomical Anatomical entities Anatomical entity NDDUO:Animal_species Animal species NDDUO:Annual_prevalence Annual prevalence NDDUO:Applied_epidemiology Applied epidemiology AD250 The application and evaluation of epidemiologic discoveries and methods in public health and health care settings, including applications of etiologic research, priority setting and evaluation of health programs, policies, and services. thing related to applied epidemiology NDDUO:Birth_defect_rate Birth defect rates Birth defect rate NDDUO:Case_cohort_studies Case cohort studies Case cohort study NDDUO:Case_study Case studies Case study NDDUO:Cause_specific_mortality_rate Cause specific mortality rates Cause specific mortality rate NDDUO:Cell_cell_interaction Cell cell interactions Cell cell interaction NDDUO:Cellular_and_sub_cellular_processes Cellular and sub cellular processes cell physiology cellular physiological process cellular physiological processes Cellular and sub cellular process NDDUO:Cellular_and_subcellular_entities cellular entities cellular entity subcellular entities subcellular entity Cellular and subcellular entity NDDUO:Clinical clinical Clinical thing NDDUO:Clinical_assesment Clinical assesments Health Assesment Health Assesments http://purl.org/cpr/0.85#clinical-examination A clinical assessment is a documented process that is used to evaluate, diagnose, and treat individuals. Clinical assesment NDDUO:Clinical_treatment clinical treatment clinical treatments thing related to clinical treatment NDDUO:Clinical_trial CBCT Clinical trial Community bases clinical trials thing related to clinical trial NDDUO:Cohort_study Cohort studies cohort study Cohort study NDDUO:Concurrent_cohort_study Concurrent cohort studies Concurrent cohort study NDDUO:Correlation_study Correlation studies Correlation study NDDUO:Cross_sectional_survey Cross sectional surveys Cross sectional survey NDDUO:Crude_mortality_rate Crude mortality rates Crude mortality rate NDDUO:Cumulative_death_rate Cumulative death rates Cumulative death rate NDDUO:Death_to_case_ratio Death to case ratios Death to case ratio NDDUO:Descriptive_epidemiology Descriptive epidemiology AD256 General observations concerning the relationship of disease to basic characteristics such as age, sex, race, occupation, and social class; also concerned with geographic location.. thing related to descriptive epidemiology NDDUO:Descriptive_statistics Descriptive statistics AD258 descriptive statistics entity NDDUO:Descriptive_study Descriptive studies Descriptive study NDDUO:Diagnosis Diagnosis AD105 thing related to diagnosis NDDUO:Diagnostic_Procedures Diagnostic Procedures http://purl.org/cpr/0.85#diagnostic-procedure Diagnostic Procedure NDDUO:Diagnostic_tests Diagnostic tests A diagnostic test is any kind of medical test performed to aid in the diagnosis or detection of disease. Diagnostic test NDDUO:Disease_rate_at_autopsy Disease rates at autopsy Disease rate at autopsy NDDUO:Distribution Distributions diffuse scattered http://purl.org/obo/owl/PATO#PATO_0001566 Distribution NDDUO:Epidemiological_study_type Epidemiological studies Epidemiological study NDDUO:Epidemiology Epidemiology AD249 Epidemiology is the study of health-event patterns in a society thing related to epidemiology NDDUO:Etiology Etiology AD444 Etiological thing NDDUO:Evaluation Evaluation NDDUO:Ex_vivo Ex vivo Ex vivo thing NDDUO:Exposure Exposure NDDUO:First_generation_migrant First generation migrant NDDUO:Frequency_measure Frequency measures http://purl.org/obo/owl/PATO#PATO_0000044 Frequency measure NDDUO:Gender sex Gender NDDUO:Genetic_causes Genetic cause AD447 Entity relating to genetic cause NDDUO:In_silico In silico In silico thing NDDUO:In_vitro In vitro In vitro thing NDDUO:In_vitro_models In vitro models http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#in_vitro_Model In vitro model NDDUO:In_vivo In vivo In vivo thing NDDUO:In_vivo_models In vivo models alzheimer's disease mouse model alzheimer's disease mouse models animal model animal models mouse model mouse models rat model rat models http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#in_vivo_Model In vivo model NDDUO:Intervention intervention treatment Thing related to intervention NDDUO:Life_time_prevalence Life time prevalence NDDUO:Measure_of_central_location Measures of central location http://purl.org/obo/owl/PATO#PATO_0002268 Measure of central location NDDUO:Measure_of_disease_ocurrence Measure of disease occurrence Measures of disease occurrence Measure of disease occurrence entity NDDUO:Measure_of_dispersion Measures of dispersion Measure of dispersion NDDUO:Measurement_scale Measurement scales Measurement scale NDDUO:Migrant_study Migrant studies Migrant study NDDUO:Molecular_and_cellular_mechanism Molecular and cellular mechanism Molecular and cellular mechanisms AD460 Molecular and cellular mechanism thing NDDUO:Molecular_entities molecular entities molecular entity Molecular entity NDDUO:Molecular_processes Molecular processes Molecular process NDDUO:Monkey Monkeys Monkey NDDUO:Morbidity Morbidity AD261 thing related to morbidity NDDUO:Morbidity_survey Morbidity surveys Morbidity survey NDDUO:Mortality Mortality NDDUO:Mortility_rate Mortility rates Mortility rate NDDUO:Mouse_ mice http://purl.org/obo/owl/NCBITaxon#NCBITaxon_10090 Mouse NDDUO:Nested_case_control_study Nested case control studies Nested case control study NDDUO:Non_clinical non clinical Non clinical thing NDDUO:Non_pharmacotherapy non pharmacotherapy treatment non pharmacotherapy treatments thing related to non pharmacotherapy clinical treatment NDDUO:Outcome outcome Thing related to outcome NDDUO:Pathogenesis Alzheimer's disease (AD) pathogenesis pathogenesis AD343 thing related to pathogenesis NDDUO:Pathology Preeclampsia-related pathological changes Preeclampsia-related pathology thing related to pathology NDDUO:Period_Prevalence Period Prevalence NDDUO:Person Alzheimer patient Alzheimer patients Alzheimer's patient Alzheimer's patients Persons Person NDDUO:Pharmacotherapy Pharmacotherapy pharmacotherapy clinical treatment pharmacotherapy clinical treatments Pharmacotherapy is the treatment of disease through the administration of drugs thing related to pharmacotherapy clinical treatment NDDUO:Point_prevalence Point prevalence NDDUO:Prevalence Prevalence AD262 thing related to prevalence NDDUO:Prevalence_rate Prevalence rates Prevalence rate NDDUO:Prognostic_study Prognostic studies Prognostic study NDDUO:Proportion Proportions proportion proportionalities proportionality quotient quotients ratio ratios http://purl.org/obo/owl/PATO#PATO_0001470 Proportion NDDUO:Race Race NDDUO:Race_specific_mortality_rate Race specific mortality rates Race specific mortality rate NDDUO:Rat Rats http://semanticscience.org/resource/SIO_000487 Rat NDDUO:Recruitment_crieteria Recruitment criteria check classifications of all subtypes and subtypes themselves!!! Recruitment criterion NDDUO:Regulation_of_gene_expression http://purl.org/obo/owl/GO#GO_0010468 Regulation of gene expression NDDUO:Retrospective_cohort_study Retrospective cohort studies Retrospective cohort study NDDUO:Risk_factor Risk factors increased risk lifestyle factor lifestyle factors risk risk factor risk factors for Alzheimer this should be filled via inference, not via direct assertions Risk factor NDDUO:Rodents Rodents http://purl.org/obo/owl/NCBITaxon#NCBITaxon_9989 Rodent NDDUO:Sampling Sampling NDDUO:Screening Screening NDDUO:Second_generation_migrant Second generation migrant NDDUO:Sex_specific_mortality_rate Sex specific mortality rates Sex specific mortality rate NDDUO:Standardized_mortality_rate Standardized mortality rates Standardized mortality rate NDDUO:Standardized_mortality_ratio Standardized mortality ratios Standardized mortality ratio NDDUO:Statistics Statistics AD257 statistics entity NDDUO:Study_design Study designs http://www.ebi.ac.uk/efo/EFO_0001426 Study design NDDUO:Study_phase Study phases Study phase NDDUO:Study_type clinical trial studies studies study clinical trial study NDDUO:Symptoms sign signs symptom symptoms http://purl.obolibrary.org/obo/OGMS_0000020 "A perceived change in function, sensation or appearance reported by a patient indicative of a disease". Symptom or sign NDDUO:Thing_that_can_act_as_a_protective_factor Thing that can act as a protective factor for Alzheimer protective factor protective factors A protective factor refers to anything that prevents or reduces vulnerability for the development of a disorder. Thing that can act as a protective factor NDDUO:Trend Trends Trend NDDUO:Vertebrate Vertebrate Vertebrate NDDUO:add_on_treatment_context add-on treatment context NDDUO:allocation_design allocation designs allocation design NDDUO:antidepressant http://en.wikipedia.org/wiki/Antidepressant antidepressants http://purl.obolibrary.org/obo/CHEBI_35469 psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia and anxiety disorders such as social anxiety disorder antidepressant NDDUO:antirheumatic_drug antirheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842 drugs used to treat rheumatoid arthritis. antirheumatic drug NDDUO:applied_epidemiology_context applied epidemiology context NDDUO:biomarker biomarkers marker markers http://purl.obolibrary.org/obo/CHEBI_59163 A substance used as an indicator of a biological state. source: http://purl.obolibrary.org/obo/CHEBI_59163 biomarker NDDUO:cellular_context cellular context NDDUO:clinical_context clinical context NDDUO:clinical_treatment_context clinical treatment context NDDUO:clinical_trial_context clinical trial context NDDUO:context context NDDUO:descriptive_epidemiology_context descriptive epidemiology context NDDUO:descriptive_statistical_context descriptive statistical context NDDUO:diagnosis_context diagnosis context NDDUO:disease_cause disease causes disease cause NDDUO:disorder disorders neurodegenerative disorder http://purl.obolibrary.org/obo/OGMS_0000045 physical basis of disease disorder NDDUO:drug_role drug roles http://purl.obolibrary.org/obo/CHEBI_23888 drug role NDDUO:drug_side_effect http://www.thefreedictionary.com/side+effect drug side effects A peripheral or secondary effect, especially an undesirable secondary effect of a drug or therapy. drug side effect NDDUO:endpoint_classification_design endpoint classification designs endpoint classification design NDDUO:epidemiology_context epidemiology context NDDUO:equipment equipment NDDUO:etiological_context etiological context NDDUO:ex_vivo_context ex vivo context NDDUO:exclusion_criterion exclusion criteria exclusion criterion NDDUO:family_based_study family based analytical studies family based analytical study NDDUO:female female NDDUO:genetic_cause_context genetic cause context NDDUO:in_silico_context in silico context NDDUO:in_vitro_context in vitro context NDDUO:in_vivo_context in vivo context NDDUO:inclusion_criterion inclusion criteria inclusion criterion NDDUO:infectious_cause_context infectious cause context NDDUO:inhibitor inhibitors Something that restrains, blocks, or suppresses. inhibitor NDDUO:intervention_context intervention context NDDUO:male men male NDDUO:masking_design masking designs masking design NDDUO:measure_of_disease_occurrence_context measure of disease occurrence context NDDUO:mechanism_of_action_context mechanism of action context NDDUO:mild_stage_context mild stage context NDDUO:model models model NDDUO:molecular_and_cellular_mechanism_context molecular and cellular mechanism context NDDUO:molecular_context molecular context NDDUO:morbidity_context morbidity context NDDUO:non_clinical_context non clinical context NDDUO:non_pharma_therapy non-pharma therapies Therapy which does not include any pharmaceutical procedures non-pharma therapy NDDUO:non_pharmacotherapy_procedure non-pharmacotherapy procedures non-pharmacotherapy procedure NDDUO:non_pharmacotherapy_treatment_context non pharmacotherapy clinical treatment context NDDUO:outcome_context outcome context NDDUO:outcome_measure outcome measures outcome measure NDDUO:pathogenesis_context pathogenesis context NDDUO:pathology_context pathology context NDDUO:pharmacotherapy_treatment_context pharmacotherapy clinical treatment context NDDUO:phase_1 phase 1 NDDUO:phase_2 phase 2 NDDUO:phase_3 phase 3 NDDUO:phase_4 phase 4 NDDUO:population_based_study population based analytical studies population based analytical study NDDUO:pre_clinical_context pre clinical context NDDUO:prevalence prevalence NDDUO:prevalence_context prevalence context NDDUO:primary_measure_context primary measure context NDDUO:primary_outcome_measure primary outcome measures primary outcome measure NDDUO:procedures_using_biomarkers_context procedures using biomarkers context NDDUO:rate rates rate NDDUO:secondary_measure_context secondary measure context NDDUO:secondary_outcome_measure secondary outcome measure secondary outcome measure NDDUO:severe_stage_context severe stage context NDDUO:stage_context stage context NDDUO:statistical_context statistical context NDDUO:study_design_context study design context NDDUO:surgery_context surgery context NDDUO:surgical_context surgical context NDDUO:syndrome_context syndrome context NDDUO:thing_related_to_surgery thing related to surgery entity snap:Continuant Definition: An entity [bfo:Entity] that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. Examples: a heart, a person, the color of a tomato, the mass of a cloud, a symphony orchestra, the disposition of blood to coagulate, the lawn and atmosphere in front of our building Synonyms: endurant continuant snap:DependentContinuant Definition: A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities. dependent_continuant snap:Disposition Definition: A realizable entity [snap:RealizableEntity] that essentially causes a specific process or transformation in the object [snap:Object] in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object [snap:Object] has the disposition D to (transform, initiate a process) R under conditions C. Examples: the disposition of vegetables to decay when not refrigerated, the disposition of a vase to brake if dropped, the disposition of blood to coagulate, the disposition of a patient with a weakened immune system to contract disease, the disposition of metal to conduct electricity. disposition snap:FiatObjectPart Definition: A material entity [snap:MaterialEntity] that is part of an object [snap:Object] but is not demarcated by any physical discontinuities. Examples: upper and lower lobes of the left lung, the dorsal and ventral surfaces of the body, the east side of Saarbruecken, the lower right portion of a human torso Synonyms: fiat substance part fiat_object_part snap:Function Definition: A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for. Examples: the function of a birth canal to enable transport, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc., the function of reproduction in the transmission of genetic material, the digestive function of the stomach to nutriate the body, the function of a hammer to drive in nails, the function of a computer program to compute mathematical equations, the function of an automobile to provide transportation, the function of a judge in a court of law function snap:GenericallyDependentContinuant Definition: A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time. Examples: a certain PDF file that exists in different and in several hard drives generically_dependent_continuant snap:IndependentContinuant Definition: A continuant [snap:Continuant] that is a bearer of quality [snap:Quality] and realizable entity [snap:RealizableEntity] entities, in which other entities inhere and which itself cannot inhere in anything. Examples: an organism, a heart, a leg, a person, a symphony orchestra, a chair, the bottom right portion of a human torso, the lawn and atmosphere in front of our building Synonyms: substantial entity independent_continuant snap:MaterialEntity Definition: An independent continuant [snap:IndependentContinuant] that is spatially extended whose identity is independent of that of other entities and can be maintained through time. Note: Material entity [snap:MaterialEntity] subsumes object [snap:Object], fiat object part [snap:FiatObjectPart], and object aggregate [snap:ObjectAggregate], which assume a three level theory of granularity, which is inadequate for some domains, such as biology. Examples: collection of random bacteria, a chair, dorsal surface of the body material_entity snap:Object Definition: A material entity [snap:MaterialEntity] that is spatially extended, maximally self-connected and self-contained (the parts of a substance are not separated from each other by spatial gaps) and possesses an internal unity. The identity of substantial object [snap:Object] entities is independent of that of other entities and can be maintained through time. Examples: an organism, a heart, a chair, a lung, an apple Synonyms: substance object snap:ObjectAggregate Definition: A material entity [snap:MaterialEntity] that is a mereological sum of separate object [snap:Object] entities and possesses non-connected boundaries. Examples: a heap of stones, a group of commuters on the subway, a collection of random bacteria, a flock of geese, the patients in a hospital Synonyms: substance aggregate object_aggregate snap:ObjectBoundary Comment: Boundaries are theoretically difficult entities to account for, however the intuitive notion of a physical boundary as a surface of some sort (whether inside or outside of a thing) will generally serve as a good guide for the use of this universal. Definition: An independent continuant [snap:IndependentContinuant] that is a lower dimensional part of a spatial entity, normally a closed two-dimensional surface. Boundaries are those privileged parts of object [snap:Object] entities that exist at exactly the point where the object [snap:Object] is separated off from the rest of the existing entities in the world. Examples: the surface of the skin, the surface of the earth, the surface of the interior of the stomach, the outer surface of a cell or cell wall Synonyms: substance boundary object_boundary snap:OneDimensionalRegion Definition: A spatial region [snap:SpatialRegion] with one dimension. Examples: the part of space that is a line stretching from one end of absolute space to the other, an edge of a cube-shaped part of space one_dimensional_region snap:Quality Definition: A specifically dependent continuant [snap:SpecificallyDependentContinuant] that is exhibited if it inheres in an entity or entities at all (a categorical property). Examples: the color of a tomato, the ambient temperature of air, the circumference of a waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee quality snap:RealizableEntity Comment: If a realizable entity [snap:RealizableEntity] inheres in a continuant [snap:Continuant], this does not imply that it is actually realized. Definition: A specifically dependent continuant [snap:SpecificallyDependentContinuant] that inheres in continuant [snap:Continuant] entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. Examples: the role of being a doctor, the function of the reproductive organs, the disposition of blood to coagulate, the disposition of metal to conduct electricity realizable_entity snap:Role Definition: A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts. Examples: the role of a person as a surgeon, the role of a chemical compound in an experiment, the role of a patient relative as defined by a hospital administrative form, the role of a woman as a legal mother in the context of system of laws, the role of a biological grandfather as legal guardian in the context of a system of laws, the role of ingested matter in digestion, the role of a student in a university role snap:Site Comment: An instance of Site [snap:Site] is a mixture of independent continuant [snap:IndependentContinuant] entities which act as surrounding environments for other independent continuant [snap:IndependentContinuant] entities, most importantly for instances of object [snap:Object]. A site [snap:Site] is typically made of object [snap:Object] or fiat object part [snap:FiatObjectPart] entities and a surrounding medium in which is found an object [snap:Object] occupying the site [snap:Site]. Independent continuant [snap:IndependentContinuant] entities may be associated with others (which, then, are site [snap:Site] entities) through a relation of "occupation". That relation is connected to, but distinct from, the relation of spatial location. Site [snap:Site] entities are not to be confused with spatial region [snap:SpatialRegion] entities. In BFO, site [snap:Site] allows for a so-called relational view of space which is different from the view corresponding to the class spatial region [snap:SpatialRegion] (see the comment on this class). Definition: An independent continuant [snap:IndependentContinuant] consisting of a characteristic spatial shape in relation to some arrangement of other continuant [snap:Continuant] entities and of the medium which is enclosed in whole or in part by this characteristic spatial shape. Site [snap:Site] entities are entities that can be occupied by other continuant [snap:Continuant] entities. Examples: a particular room in a particular hospital, Maria's nostril or her intestines for a variety of bacteria. site snap:SpatialRegion Comment: All instances of continuant [snap:Continuant] are spatial entities, that is, they enter in the relation of (spatial) location with spatial region [snap:SpatialRegion] entities. As a particular case, the exact spatial location of a spatial region [snap:SpatialRegion] is this region itself. Comment: An instance of spatial region [snap:SpatialRegion] is a part of space. All parts of space are spatial region [snap:SpatialRegion] entities and only spatial region [snap:SpatialRegion] entities are parts of space. Space is the entire extent of the spatial universe, a designated individual, which is thus itself a spatial region [snap:SpatialRegion]. Comment: Space and spatial region [snap:SpatialRegion] entities are entities in their own rights which exist independently of any entities which can be located at them. This view of space is sometimes called "absolutist" or "the container view". In BFO, the class site [snap:Site] allows for a so-called relational view of space, that is to say, a view according to which spatiality is a matter of relative location between entities and not a matter of being tied to space. The bridge between these two views is secured through the fact that while instances of site [snap:Site] are not spatial region [snap:SpatialRegion] entities, they are nevertheless spatial entities. Definition: A continuant [snap:Continuant] that is neither bearer of quality [snap:Quality] entities nor inheres in any other entities. Examples: the sum total of all space in the universe, parts of the sum total of all space in the universe spatial_region snap:SpecificallyDependentContinuant Definition: A continuant [snap:Continuant] that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. Examples: the mass of a cloud, the smell of mozzarella, the liquidity of blood, the color of a tomato, the disposition of fish to decay, the role of being a doctor, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc. Synonyms: property, trope, mode specifically_dependent_continuant snap:ThreeDimensionalRegion Definition: A spatial region [snap:SpatialRegion] with three dimensions. Examples: a cube-shaped part of space, a sphere-shaped part of space three_dimensional_region snap:TwoDimensionalRegion Definition: A spatial region [snap:SpatialRegion] with two dimensions. Examples: the surface of a cube-shaped part of space, the surface of a sphere-shaped part of space, the surface of a rectilinear planar figure-shaped part of space two_dimensional_region snap:ZeroDimensionalRegion Definition: A spatial region [snap:SpatialRegion] with no dimensions. Examples: a point zero_dimensional_region span:ConnectedSpatiotemporalRegion Definition: A spatiotemporal region [span:SpatiotemporalRegion] that has temporal and spatial dimensions such that all points within the spatiotemporal region are mediately or immediately connected to all other points within the same spatiotemporal region [span:SpatiotemporalRegion]. Examples: the spatial and temporal location of an individual organism's life, the spatial and temporal location of the development of a fetus connected_spatiotemporal_region span:ConnectedTemporalRegion Definition: A temporal region [span:TemporalRegion] every point of which is mediately or immediately connected with every other point of which. Examples: the 1970s years, the time from the beginning to the end of a heart attack, the time taken up by cellular meiosis connected_temporal_region span:FiatProcessPart Definition: A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities. Examples: chewing during a meal, the middle part of a rainstorm, the worst part of a heart-attack, the most interesting part of Van Gogh's life fiat_process_part span:Occurrent Definition: An entity [bfo:Entity] that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants. Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor Synonyms: perdurant occurrent span:Process Definition: A processual entity [span:ProcessualEntity] that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities. Examples: the life of an organism, the process of sleeping, the process of cell-division process span:ProcessAggregate Definition: A processual entity [span:ProcessualEntity] that is a mereological sum of process [span:Process] entities and possesses non-connected boundaries. Examples: the beating of the hearts of each of seven individuals in the room, the playing of each of the members of an orchestra, a process of digestion and a process of thinking taken together process_aggregate span:ProcessBoundary Definition: A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary. Examples: birth, death, the forming of a synapse, the onset of REM sleep, the detaching of a finger in an industrial accident, the final separation of two cells at the end of cell-division, the incision at the beginning of a surgery process_boundary span:ProcessualContext Comment: An instance of a processual context [span:ProcessualContext] is a mixture of processual entity [span:ProcessualEntity] which stand as surrounding environments for other processual entity [span:ProcessualEntity] entities. The class processual context [span:ProcessualContext] is the analogous among occurrent [span:Occurrent] entities to the class site [snap:Site] among continuant [snap:Continuant] entities. Definition: An occurrent [span:Occurrent] consisting of a characteristic spatial shape inhering in some arrangement of other occurrent [span:Occurrent] entities. Processual context [span:ProcessualContext] entities are characteristically entities at or in which other occurrent [span:Occurrent] entities can be located or occur. Examples: The processual context for a given manipulation occurring as part of an experiment is made of processual entities which occur in parallel, are not necessarily all parts of the experiment themselves and may involve continuant [snap:Continuant] entities which are in the spatial vicinity of the participants in the experiment. processual_context span:ProcessualEntity Definition: An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. Examples: the life of an organism, the process of meiosis, the course of a disease, the flight of a bird processual_entity span:ScatteredSpatiotemporalRegion Definition: A spatiotemporal region [span:SpatiotemporalRegion] that has spatial and temporal dimensions and every spatial and temporal point of which is not connected with every other spatial and temporal point of which. Examples: the space and time occupied by the individual games of the World Cup, the space and time occupied by the individual liaisons in a romantic affair scattered_spatiotemporal_region span:ScatteredTemporalRegion Definition: A temporal region [span:TemporalRegion] every point of which is not mediately or immediately connected with every other point of which. Examples: the time occupied by the individual games of the World Cup, the time occupied by the individual liaisons in a romantic affair scattered_temporal_region span:SpatiotemporalInstant Definition: A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment. Examples: the spatiotemporal region occupied by a single instantaneous temporal slice (part) of a process spatiotemporal_instant span:SpatiotemporalInterval Definition: A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] that endures for more than a single moment of time. Examples: the spatiotemporal region occupied by a process or by a fiat processual part spatiotemporal_interval span:SpatiotemporalRegion Comment: All instances of occurrent [span:Occurrent] are spatiotemporal entities, that is, they enter in the relation of (spatiotemporal) location with spatiotemporal region [span:SpatiotemporalRegion] entities. As a particular case, the exact spatiotemporal location of a spatiotemporal region [span:SpatiotemporalRegion] is this region itself. Comment: An instance of the spatiotemporal region [span:SpatiotemporalRegion] is a part of spacetime. All parts of spacetime are spatiotemporal region [span:SpatiotemporalRegion] entities and only spatiotemporal region [span:SpatiotemporalRegion] entities are parts of spacetime. In particular, neither spatial region [snap:SpatialRegion] entities nor temporal region [span:TemporalRegion] entities are in BFO parts of spacetime. Spacetime is the entire extent of the spatiotemporal universe, a designated individual, which is thus itself a spatiotemporal region [span:SpatiotemporalRegion]. Spacetime is among occurrents the analogous of space among continuant [snap:Continuant] entities. Comment: Spacetime and spatiotemporal region [span:SpatiotemporalRegion] entities are entities in their own rights which exist independently of any entities which can be located at them. This view of spacetime can be called "absolutist" or "the container view". In BFO, the class processual context [span:ProcessualContext] allows for a so-called relational view of spacetime, that is to say, a view according to which spatiotemporality is a matter of relative location between entities and not a matter of being tied to spacetime. In BFO, the bridge between these two views is secured through the fact that instances of processual context [span:ProcessualContext] are too spatiotemporal entities. Definition: An occurrent [span:Occurrent] at or in which processual entity [span:ProcessualEntity] entities can be located. Examples: the spatiotemporal region occupied by a human life, the spatiotemporal region occupied by the development of a cancer tumor, the spatiotemporal context occupied by a process of cellular meiosis spatiotemporal_region span:TemporalInstant Definition: A connected temporal region [span:ConnectedTemporalRegion] comprising a single moment of time. Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death temporal_instant span:TemporalInterval Definition: A connected temporal region [span:ConnectedTemporalRegion] lasting for more than a single moment of time. Examples: any continuous temporal duration during which a process occurs temporal_interval span:TemporalRegion Comment: All instances of occurrent [span:Occurrent] are temporal entities, that is, they enter in the relation of (temporal) location with temporal region [span:TemporalRegion] entities. As a particular case, the exact spatiotemporal location of a temporal region [span:TemporalRegion] is this region itself. Continuant [snap:Continuant] entities are not temporal entities in the technical sense just explained; they are related to time in a different way, not through temporal location but through a relation of existence at a time or during a period of time (see continuant [snap:Continuant]. Comment: An instance of temporal region [span:TemporalRegion] is a part of time. All parts of time are temporal region [span:TemporalRegion] entities and only temporal region [span:TemporalRegion] entities are parts of time. Time is the entire extent of the temporal universe, a designated individual, which is thus a temporal region itself. Comment: Time and temporal region [span:TemporalRegion] entities are entities in their own rights which exist independently of any entities which can be located at them. This view of time can be called "absolutist" or "the container view" in analogy to what is traditionally the case with space (see spatial region [snap:SpatialRegion]. Definition: An occurrent [span:Occurrent] that is part of time. Examples: the time it takes to run a marathon, the duration of a surgical procedure, the moment of death temporal_region peo:ACE http://www.ncbi.nlm.nih.gov/gene/1636 ACE peo:ACE2 http://www.ncbi.nlm.nih.gov/gene/59272 ACE2 peo:ACHE http://view.ncbi.nlm.nih.gov/gene/43 ACHE peo:ADIPOQ http://view.ncbi.nlm.nih.gov/gene/9370 ADIPOQ peo:ADRB2 http://view.ncbi.nlm.nih.gov/gene/154 ADRB2 peo:ADTRP http://view.ncbi.nlm.nih.gov/gene/84830 ADTRP peo:AGT http://view.ncbi.nlm.nih.gov/gene/183 AGT peo:AGTR AGTR family AGTR peo:AGTR1 http://view.ncbi.nlm.nih.gov/gene/185 AGTR1 peo:AGTR2 http://view.ncbi.nlm.nih.gov/gene/186 AGTR2 peo:ANKS1B http://view.ncbi.nlm.nih.gov/gene/56899 ANKS1B peo:ATF6 http://view.ncbi.nlm.nih.gov/gene/22926 ATF6 peo:Angiogenic_factors Angiogenic factors peo:BAX http://www.ncbi.nlm.nih.gov/gene/581 BAX peo:BCL2 http://www.ncbi.nlm.nih.gov/gene/596 BCL2 peo:BTC http://www.ncbi.nlm.nih.gov/gene/685 BTC peo:Bradykinin_receptors http://purl.bioontology.org/ontology/MESH/D018002 BDKR family Bradykinin receptors peo:CAT http://view.ncbi.nlm.nih.gov/gene/847 CAT peo:CHI3L1 http://www.ncbi.nlm.nih.gov/gene/1116 CHI3L1 peo:CORIN http://www.ncbi.nlm.nih.gov/gene/10699 CORIN peo:CST3 http://www.ncbi.nlm.nih.gov/gene/1471 CST3 peo:CUEDC1 http://view.ncbi.nlm.nih.gov/gene/404093 CUEDC1 peo:CXCL2 http://www.ncbi.nlm.nih.gov/gene/2920 CXCL2 peo:CXCL8 http://www.ncbi.nlm.nih.gov/gene/3576 CXCL8 peo:Cytokines http://purl.bioontology.org/ontology/MESH/D016207 Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. Cytokines peo:DHX34 http://www.ncbi.nlm.nih.gov/gene/9704 DHX34 peo:DNAJC5G http://www.ncbi.nlm.nih.gov/gene/285126 DNAJC5G peo:EDN1 http://www.ncbi.nlm.nih.gov/gene/1906 EDN1 peo:EDNRB http://www.ncbi.nlm.nih.gov/gene/1910 EDNRB peo:EGF_family EGF Epidermal Growth Factor-Urogastrone Epidermal growth factor Growth Factor, Epidermal Growth Factor-Urogastrone, Epidermal Human Urinary Gastric Inhibitor Urogastrone beta Urogastrone beta-Urogastrone http://purl.bioontology.org/ontology/MESH/D004815 A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. EGF family peo:EIF2 eukaryotic translation initiation factor 2 EIF2 peo:EIF2AK3 http://www.ncbi.nlm.nih.gov/gene/9451 EIF2AK3 peo:EMD http://www.ncbi.nlm.nih.gov/gene/2010 EMD peo:ENG http://www.ncbi.nlm.nih.gov/gene/2022 ENG peo:ENV http://www.ncbi.nlm.nih.gov/gene/155971 ENV peo:ERN1 http://www.ncbi.nlm.nih.gov/gene/2081 ERN1 peo:ERVFRD-1 http://view.ncbi.nlm.nih.gov/gene/405754 ERVFRD-1 peo:ERVW-1 http://view.ncbi.nlm.nih.gov/gene/30816 ERVW-1 peo:ESR1 http://www.ncbi.nlm.nih.gov/gene/2099 ESR1 peo:ESR2 http://www.ncbi.nlm.nih.gov/gene/2100 ESR2 peo:Endogenous_ligands Endogenous ligands peo:F7 http://view.ncbi.nlm.nih.gov/gene/2155 F7 peo:F9 http://view.ncbi.nlm.nih.gov/gene/2158 F9 peo:FASLG http://view.ncbi.nlm.nih.gov/gene/356 FASLG peo:FLT1 http://www.ncbi.nlm.nih.gov/gene/2321 FLT1 peo:FURIN http://www.ncbi.nlm.nih.gov/gene/5045 FURIN peo:GOT glutamic-oxaloacetic transaminase GOT peo:GPT http://www.ncbi.nlm.nih.gov/gene/2875 GPT peo:GTSF1 http://view.ncbi.nlm.nih.gov/gene/121355 GTSF1 peo:G_protein-coupled_receptors G Protein Coupled Receptors G-Protein-Coupled Receptors Receptors, G Protein Coupled http://purl.bioontology.org/ontology/MESH/D043562 The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS. G protein coupled receptors peo:Groucho http://www.ncbi.nlm.nih.gov/gene/100303594 Gro Groucho peo:HCG26 http://view.ncbi.nlm.nih.gov/gene/352961 HCG26 peo:HMOX1 http://www.ncbi.nlm.nih.gov/gene/3162 HMOX1 peo:HSP90B1 http://www.ncbi.nlm.nih.gov/gene/7184 HSP90B1 peo:HSPA5 http://www.ncbi.nlm.nih.gov/gene/1910 HSPA5 peo:IFNG http://www.ncbi.nlm.nih.gov/gene/3458 IFNG peo:IGF http://purl.bioontology.org/ontology/MEDDRA/10062735 insulin-like growth factor IGF peo:IGF1R http://www.ncbi.nlm.nih.gov/gene/3480 IGF1R peo:IL10 http://www.ncbi.nlm.nih.gov/gene/3586 IL10 peo:IL17A http://www.ncbi.nlm.nih.gov/gene/3605 IL17A peo:IL1A http://www.ncbi.nlm.nih.gov/gene/3552 IL1A peo:IL2 http://www.ncbi.nlm.nih.gov/gene/3558 IL2 peo:IL4 http://www.ncbi.nlm.nih.gov/gene/3565 IL4 peo:IL6 http://www.ncbi.nlm.nih.gov/gene/3569 IL6 peo:INGX http://www.ncbi.nlm.nih.gov/gene/27160 INGX peo:KCNN KCNN peo:KCNN2 http://www.ncbi.nlm.nih.gov/gene/3781 KCNN2 peo:KCNN3 http://www.ncbi.nlm.nih.gov/gene/3782 KCNN3 peo:KLK kallikrein-related peptidase KLK peo:KLRK1 http://www.ncbi.nlm.nih.gov/gene/22914 KLRK1 peo:KNG1 http://www.ncbi.nlm.nih.gov/gene/3827 KNG1 peo:LAIR2 http://www.ncbi.nlm.nih.gov/gene/3904 LAIR2 peo:LAMA3 http://www.ncbi.nlm.nih.gov/gene/3909 LAMA3 peo:LDH lactate dehydrogenase LDH peo:LDLR http://www.ncbi.nlm.nih.gov/gene/3949 LDLR peo:LEMD1 http://www.ncbi.nlm.nih.gov/gene/93273 LEMD1 peo:LTBR http://www.ncbi.nlm.nih.gov/gene/4055 LTBR peo:LY6K http://www.ncbi.nlm.nih.gov/gene/54742 LY6K peo:LYZ http://www.ncbi.nlm.nih.gov/gene/4069 LYZ peo:LYZL1 http://view.ncbi.nlm.nih.gov/gene/84569 LYZL1 peo:Laminins http://purl.bioontology.org/ontology/MESH/D007797 Chain, Laminin M Glycoprotein GP 2 Glycoprotein GP-2 Laminin M Laminin M Chain M Chain, Laminin Merosin Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion. Laminins peo:MADCAM1 http://www.ncbi.nlm.nih.gov/gene/8174 MADCAM1 peo:MDA Melanoma Differentiation-Associated protein MDA peo:MFSD2A http://www.ncbi.nlm.nih.gov/gene/84879 MFSD2A peo:MMP2 http://www.ncbi.nlm.nih.gov/gene/4313 MMP2 peo:MMP9 http://www.ncbi.nlm.nih.gov/gene/4318 MMP9 peo:MMPs http://purl.bioontology.org/ontology/MESH/D020782 Matrix Metalloproteinases Metalloproteinases, Matrix A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components. MMPs peo:MXRA5 http://view.ncbi.nlm.nih.gov/gene/25878 MXRA5 peo:NME9 http://view.ncbi.nlm.nih.gov/gene/347736 NME9 peo:NR3C2 http://www.ncbi.nlm.nih.gov/gene/4306 NR3C2 peo:OR51G1 http://view.ncbi.nlm.nih.gov/gene/79324 OR51G1 peo:Oxidase Oxidase (substance) http://purl.bioontology.org/ontology/SNOMEDCT/129921004 Oxidase peo:PAPPA http://www.ncbi.nlm.nih.gov/gene/5069 PAPPA peo:PGF http://www.ncbi.nlm.nih.gov/gene/5228 PGF peo:PIGF http://www.ncbi.nlm.nih.gov/gene/5281 PIGF peo:PRIMA1 http://www.ncbi.nlm.nih.gov/gene/145270 PRIMA1 peo:PROC http://www.ncbi.nlm.nih.gov/gene/5624 PROC peo:PROS1 http://www.ncbi.nlm.nih.gov/gene/5627 PROS1 peo:REN http://www.ncbi.nlm.nih.gov/gene/5972 REN peo:RGS2 http://www.ncbi.nlm.nih.gov/gene/5997 RGS2 peo:RIPPLY1 http://www.ncbi.nlm.nih.gov/gene/92129 RIPPLY1 peo:RNASE11 http://view.ncbi.nlm.nih.gov/gene/122651 RNASE11 peo:ROS1 http://www.ncbi.nlm.nih.gov/gene/6098 ROS1 peo:SERPINC1 http://www.ncbi.nlm.nih.gov/gene/462 SERPINC1 peo:SERPINE1 http://www.ncbi.nlm.nih.gov/gene/5054 SERPINE1 peo:SGSM1 http://www.ncbi.nlm.nih.gov/gene/129049 SGSM1 peo:SLAMF1 http://www.ncbi.nlm.nih.gov/gene/6504 SLAMF1 peo:SLC17A5 http://www.ncbi.nlm.nih.gov/gene/26503 SLC17A5 peo:SLC1A4 http://www.ncbi.nlm.nih.gov/gene/6509 ASCT1 SLC1A4 peo:SLC1A5 http://www.ncbi.nlm.nih.gov/gene/6510 ASCT2 SLC1A5 peo:SOD Superoxide Dismutase SOD peo:SSTR somatostatin receptor SSTR peo:SSTR1 http://www.ncbi.nlm.nih.gov/gene/6751 SSTR1 peo:SYNC http://view.ncbi.nlm.nih.gov/gene/81493 SYNC peo:SYT6 http://www.ncbi.nlm.nih.gov/gene/148281 SYT6 peo:TGFB1 http://www.ncbi.nlm.nih.gov/gene/7040 TGFB1 peo:TIMPs http://purl.bioontology.org/ontology/MESH/D019714 Metalloproteinases Tissue Inhibitor Tissue Inhibitor of Metalloproteinases A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes. TIMPs peo:TNF http://purl.bioontology.org/ontology/MESH/C439524 TNF protein, human TNF superfamily, member 2 protein, human TNF-2 protein, human TNFSF2 protein, human tumor necrosis factor 2 protein, human tumor necrosis factor, human tumor necrosis factor-2 protein, human tumor necrosis factor-alpha promoter allele-2 protein, human TNF peo:TNFRSF14 http://www.ncbi.nlm.nih.gov/gene/8764 TNFRSF14 peo:TNFRSF6B http://www.ncbi.nlm.nih.gov/gene/8771 TNFRSF6B peo:TNFSF14 http://www.ncbi.nlm.nih.gov/gene/8740 TNFSF14 peo:TNFSF15 http://www.ncbi.nlm.nih.gov/gene/9966 TNFSF15 peo:TPSAB1 http://www.ncbi.nlm.nih.gov/gene/7177 TPSAB1 peo:TRIM31 http://www.ncbi.nlm.nih.gov/gene/11074 TRIM31 peo:VEGFA http://www.ncbi.nlm.nih.gov/gene/7422 VEGFA peo:VEGFR http://purl.bioontology.org/ontology/OMIM/191306 FLK1 KDR KINASE INSERT DOMAIN RECEPTOR TYROSINE KINASE GROWTH FACTOR RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 VEGFR2 VEGFR peo:WNT Wingless Type Proteins Wnt Factors Wnt Proteins http://purl.bioontology.org/ontology/MESH/D051153 Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN. WNT peo:gene genes gene peo2:A-type_natriuretic_peptide ANH - Atrial natriuretic hormone ANP - Atrial natriuretic peptide Atrial natriuretic factor Atrial natriuretic factor (substance) Atrial natriuretic hormone Atrial natriuretic peptide Atriopeptin http://purl.bioontology.org/ontology/SNOMEDCT/30326004 A-type natriuretic peptide peo2:ACE_inhibitor ACE inhibitors angiotensin-converting enzyme inhibitor http://purl.obolibrary.org/obo/CHEBI_35457 ACE inhibitor peo2:ADRB_blockers ADRB blockers peo2:AGT_precursor http://www.uniprot.org/uniprot/P01019 AGT precursor peo2:AT1R_antagonists AT1R antagonists peo2:AT2R_antagonists AT2R antagonists peo2:Abdominal_pain acute abdominal pain Abdominal pain peo2:Abortion_Habitual http://purl.bioontology.org/ontology/MESH/D000026 Abortion, Recurrent Abortions, Habitual Abortions, Recurrent Habitual Abortion Habitual Abortions Miscarriage, Recurrent Miscarriages, Recurrent Recurrent Abortion Recurrent Abortions Recurrent Miscarriage Recurrent Miscarriages Three or more consecutive spontaneous abortions. Abortion, Habitual peo2:Absolute_risk AD299 Absolute risk peo2:Academic_progress Academic progress (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/370973005 Academic progress peo2:Acetylation protein amino acid acetylation AD594 Acetylation peo2:Acute_disease_of_cardiovascular_system Acute cardiovascular disease Acute cardiovascular disorder Acute disease of cardiovascular system (disorder) Acute disorder of cardiovascular system http://purl.bioontology.org/ontology/SNOMEDCT/128487001 Acute disease of cardiovascular system peo2:Acute_pulmonary_edema Acute edema of lung Acute oedema of lung Acute pulmonary edema (disorder) Acute pulmonary oedema Pulmonary edema - acute Pulmonary oedema - acute http://purl.bioontology.org/ontology/SNOMEDCT/40541001 Acute pulmonary edema peo2:Admission_to_intensive_care_unit Admission to intensive care unit (procedure) Admit to ITU Admit to intensive care unit ICU - Admission to intensive care unit http://purl.bioontology.org/ontology/SNOMEDCT/305351004 Admission to intensive care unit peo2:Admission_to_neonatal_intensive_care_unit Admission to NICU Admission to neonatal intensive care unit peo2:Adrenal_disease Adrenal disease peo2:After_full_dilatation_of_cervix After full dilatation of cervix (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255617004 After full dilatation of cervix peo2:Age_at_birth age at birth age-at-birth maternal age Age at birth peo2:Age_at_leaving_school Age at leaving school (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224287007 Age at leaving school peo2:Age_at_menarche Age at menarche (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/398700009 Age at menarche peo2:Age_at_onset age at onset age-at-onset maternal age Age at onset peo2:Age_at_starting_school Age at starting school (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224286003 Age at starting school peo2:Albuminuria Albuminuria (finding) http://purl.bioontology.org/ontology/SNOMEDCT/274769005 Albuminuria peo2:Alcohol_abuse AA - Alcohol abuse Alcohol abuse (disorder) Ethanol abuse http://purl.bioontology.org/ontology/SNOMEDCT/15167005 Alcohol abuse peo2:Alcohol_intake AI - Alcohol intake Alcohol consumption Alcohol intake (observable entity) Alcoholic drink intake ETOH - Alcohol intake Ethanol intake http://purl.bioontology.org/ontology/SNOMEDCT/160573003 Alcohol intake peo2:Allergy_to_substance Allergy to substance (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/419199007 Allergy to substance peo2:Ambulatory_blood_pressure_recording Ambulatory blood pressure recording (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/164783007 Ambulatory blood pressure recording peo2:Aminopterin CHEMBL274619 Aminopterin peo2:Amnesia Amnesia (finding) Dysmnesia LOM - Loss of memory Loss of memory Memory gone Memory loss Memory loss - amnesia http://purl.bioontology.org/ontology/SNOMEDCT/48167000 Amnesia peo2:Amnion Amnions Amniotic Membrane Amniotic Membranes Membrane, Amniotic Membranes, Amniotic http://purl.bioontology.org/ontology/MESH/D000650 The innermost membranous sac that surrounds and protects the developing embryo which is bathed in the AMNIOTIC FLUID. Amnion cells are secretory EPITHELIAL CELLS and contribute to the amniotic fluid. Amnion peo2:Amnion_nodosum Amnion nodosum (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/71473008 Amnion nodosum peo2:Amniotic_fluid AF - Amniotic fluid Amniotic fluid (substance) Liquor http://purl.bioontology.org/ontology/SNOMEDCT/77012006 Amniotic fluid peo2:Amount_of_blood_loss Amount of blood loss peo2:Analysis_of_cohort_studies check subclasses!! AD298 Analysis of cohort studies peo2:Androgen_level Androgen level (procedure) Androgen measurement http://purl.bioontology.org/ontology/SNOMEDCT/407709006 Androgen level peo2:Androgen_receptor_level androgen receptor levels Androgen receptor level peo2:Anemia Absolute anaemia Absolute anemia Anaemia Anemia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/271737000 Anemia peo2:Angioedema Angio-oedema Angio-oedema-urticaria Angioedema (disorder) Angioedema-urticaria Angioneurotic edema Angioneurotic oedema Giant urticaria Quincke's disease Quincke's edema Quincke's oedema Urticaria-angio-oedema Urticaria-angioedema http://purl.bioontology.org/ontology/SNOMEDCT/41291007 Angioedema peo2:Angiotensin_II http://purl.bioontology.org/ontology/MESH/D000804 5 L Isoleucine Angiotensin II 5-L-Isoleucine Angiotensin II ANG-(1-8)Octapeptide Angiotensin II, 5-L-Isoleucine Angiotensin II, Ile(5)- Angiotensin II, Isoleucine(5)- Angiotensin II, Val(5)- Angiotensin II, Valine(5)- Angiotensin-(1-8) Octapeptide II, 5-L-Isoleucine Angiotensin Isoleucine(5)-Angiotensin Isoleucyl(5)-Angiotensin II Valyl(5)-Angiotensin II An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS. Angiotensin II peo2:Angiotensin_II_system http://www.genome.jp/kegg-bin/show_pathway?map04614 RAS renin-angiotensin system Angiotensin II system peo2:Antenatal AN - Antenatal Antenatal (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/263675000 Antenatal peo2:Antepartum Antepartum (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/276986009 Antepartum peo2:Antepartum_hemorrhage APH - Antepartum haemorrhage APH - Antepartum hemorrhage Antepartum haemorrhage Antepartum hemorrhage (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/34842007 Antepartum hemorrhage peo2:Antibody Antibody (substance) http://purl.bioontology.org/ontology/SNOMEDCT/68498002 Antibody peo2:Antihypertensive_medication Antihypertensive medication peo2:Antihypertensive_therapy Antihypertensive therapy (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/308116003 Antihypertensive therapy peo2:Antiphospholipid_syndrome_in_pregnancy Antiphospholipid syndrome in pregnancy (disorder) systemic lupus erythematosus http://purl.bioontology.org/ontology/SNOMEDCT/72161000119100 Antiphospholipid syndrome in pregnancy peo2:Antiproliferative_effects Antiproliferative effects peo2:Antipsychotic_drugs http://www.omnimedicalsearch.com/conditions-diseases/alzheimers-disease-treatment-prevention.html Antipsychotic drugs Neuroleptic antipsychotic antipsychotics http://purl.obolibrary.org/obo/CHEBI_35476 AD004 An antipsychotic is a tranquilizing psychiatric medication primarily used to manage psychosis (including delusions or hallucinations, as well as disordered thought), particularly in schizophrenia and bipolar disorder Antipsychotic drug peo2:Antithyroid_agent Antithyroid agent (substance) http://purl.bioontology.org/ontology/SNOMEDCT/418416001 Antithyroid agent peo2:Apgar_score_low http://purl.bioontology.org/ontology/MEDDRA/10002944 Apgar score low peo2:Apoptosis Apoptoses, Extrinsic Pathway Apoptoses, Intrinsic Pathway Apoptosis, Extrinsic Pathway Apoptosis, Intrinsic Pathway Extrinsic Pathway Apoptoses Extrinsic Pathway Apoptosis Intrinsic Pathway Apoptoses Intrinsic Pathway Apoptosis Programmed Cell Death, Type I http://purl.bioontology.org/ontology/MESH/D017209 Apoptosis that is triggered via cell stress and mitochondrial damage. One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. Apoptosis that is triggered via CELL SURFACE RECEPTORS such as TUMOR NECROSIS FACTOR RECEPTORS and DEATH DOMAIN RECEPTORS. Apoptosis peo2:Arterial_Pressure Aortic Blood Pressure Aortic Blood Pressures Aortic Pressure Aortic Pressure, Mean Aortic Pressures Aortic Pressures, Mean Aortic Pulse Pressure Aortic Pulse Pressures Aortic Tension Aortic Tensions Arterial Blood Pressure Arterial Blood Pressures Arterial Pressure, Mean Arterial Pressures Arterial Pressures, Mean Arterial Tension Arterial Tensions Blood Pressure, Aortic Blood Pressure, Arterial Blood Pressures, Aortic Blood Pressures, Arterial Mean Aortic Pressure Mean Aortic Pressures Mean Arterial Pressure Mean Arterial Pressures Pressure, Aortic Pressure, Aortic Blood Pressure, Aortic Pulse Pressure, Arterial Pressure, Arterial Blood Pressure, Mean Aortic Pressure, Mean Arterial Pressures, Aortic Pressures, Aortic Blood Pressures, Aortic Pulse Pressures, Arterial Pressures, Arterial Blood Pressures, Mean Aortic Pressures, Mean Arterial Pulse Pressure, Aortic Pulse Pressures, Aortic Tension, Aortic Tension, Arterial Tensions, Aortic Tensions, Arterial http://purl.bioontology.org/ontology/MESH/D062186 Difference between systolic and diastolic pressures within AORTA Blood pressure within AORTA The blood pressure in the ARTERIES. It is commonly measured with a SPHYGMOMANOMETER on the upper arm which represents the arterial pressure in the BRACHIAL ARTERY. The average pressure during the aortic pulse cycle. The average arterial pressure during a single cardiac cycle. It can be estimated as diastolic blood pressure plus one third of the difference of diastolic and systolic blood pressures. Arterial Pressure peo2:Arterial_thrombosis Arterial thrombosis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/65198009 Arterial thrombosis peo2:Arteries Artery http://purl.bioontology.org/ontology/MESH/D001158 The vessels carrying blood away from the heart. Arteries peo2:Arteriosclerosis Arteriosclerosis (morphologic abnormality) http://purl.bioontology.org/ontology/SNOMEDCT/28960008 Arteriosclerosis peo2:Arthritis Arthritis (disorder) Inflammatory arthritis Joint inflammation http://purl.bioontology.org/ontology/SNOMEDCT/3723001 Arthritis peo2:Artificial_insemination AI - Artificial insemination Artificial insemination (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/58533008 Artificial insemination peo2:Asian_race Asian Asian race (racial group) http://purl.bioontology.org/ontology/SNOMEDCT/413582008 Asian race peo2:Aspirin Acetylsalicylic acid Aspirin (product) http://purl.bioontology.org/ontology/SNOMEDCT/7947003 Aspirin peo2:Aspirin_allergy Aspirin allergy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/293586001 Aspirin allergy peo2:Asthma Airway hyperreactivity Asthma (disorder) Asthmatic BHR - Bronchial hyperreactivity Bronchial asthma Bronchial hyperreactivity Bronchial hyperresponsiveness Bronchial hypersensitivity Hyperreactive airway disease http://purl.bioontology.org/ontology/SNOMEDCT/195967001 Asthma peo2:At_crowning_of_head At crowning of head (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255615007 At crowning of head peo2:At_delivery_before_labor At delivery before labor peo2:At_delivery_of_anterior_shoulder At delivery of anterior shoulder (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255614006 At delivery of anterior shoulder peo2:At_discharge_from_hospital At discharge from hospital peo2:Atherogenic_lipoprotein Atherogenic lipoprotein peo2:Atherosclerosis Atheromatosis Atherosclerosis (morphologic abnormality) http://purl.bioontology.org/ontology/SNOMEDCT/38716007 Atherosclerosis peo2:Atrial_fibrillation AF - Atrial fibrillation Atrial fibrillation (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/49436004 Atrial fibrillation peo2:Attributable_risks AD300 Attributable risks peo2:Autoimmune_Diseases Autoimmune Disease Disease, Autoimmune Diseases, Autoimmune http://purl.bioontology.org/ontology/MESH/D001327 Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. Autoimmune Diseases peo2:Availability_of_caesarean_section Availability of caesarean section peo2:Availability_of_medical_resources Availability of medical resources peo2:B-lines comet tail artifact B-lines peo2:BK_channel BK channel peo2:B_lymphocyte B cell B lymphocyte (cell) B-cell http://purl.bioontology.org/ontology/SNOMEDCT/112130006 B lymphocyte peo2:Bariatric_Surgery Bariatric Surgeries Bariatric Surgical Procedure Bariatric Surgical Procedures Metabolic Surgeries Metabolic Surgery Procedure, Bariatric Surgical Procedures, Bariatric Surgical Stapling, Stomach Stomach Stapling Surgeries, Bariatric Surgeries, Metabolic Surgery, Bariatric Surgery, Metabolic Surgical Procedure, Bariatric Surgical Procedures, Bariatric http://purl.bioontology.org/ontology/MESH/D050110 Surgical procedures aimed at affecting metabolism and producing major WEIGHT REDUCTION in patients with MORBID OBESITY. Bariatric Surgery peo2:Basement_membrane Basal lamina Basement membrane (body structure) External lamina Membrana basalis http://purl.bioontology.org/ontology/SNOMEDCT/68989006 Basement membrane peo2:Basic_attribute_on_pregnancy Basic attrubute Basic attribute on pregnancy peo2:Before_full_dilatation_of_cervix Before full dilatation of cervix (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255616008 Before full dilatation of cervix peo2:Bilateral_notching Bilateral notching peo2:Bilateral_protodiastolic_notches Bilateral protodiastolic notches peo2:Bilirubin_total_measurement Bilirubin, total measurement (procedure) Total bilirubin Total bilirubin level http://purl.bioontology.org/ontology/SNOMEDCT/359986008 Bilirubin, total measurement peo2:Biochemical_test http://purl.bioontology.org/ontology/SNOMEDCT/183821000 Biochemical test peo2:Birth Birth (finding) http://purl.bioontology.org/ontology/SNOMEDCT/3950001 Birth peo2:Birth_weight Birth weight (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364589006 Birth weight peo2:Birth_weight_of_the_pregnant_woman Birth weight of the pregnant woman peo2:Black_-_ethnic_group Black Black - ethnic group (ethnic group) http://purl.bioontology.org/ontology/SNOMEDCT/315240009 Black - ethnic group peo2:Blood_Biomarker A. Hye, S. Lynham, and S. Lynham, “Proteome-based plasma biomarkers for Alzheimer's disease,”Brain, vol. 129, no. 11, pp. 3042–3050, 2006. Y.-M. Kuo, T. A. Kokjohn, and T. A. Kokjohn, “Amyloid-β peptides interact with plasma proteins and erythrocytes: implications for their quantitation in plasma,” Biochemical and Biophysical Research Communications, vol. 268, no. 3, pp. 750–756, 2000. H. Fukumoto, M. Tennis, J. J. Locascio, B. T. Hyman, J. H. Growdon, and M. C. Irizarry, “Age but not diagnosis is the main predictor of plasma amyloid β-protein levels,” Archives of Neurology, vol. 60, no. 7, pp. 958–964, 2003 blood Biomarkers AD108 blood Biomarker peo2:Blood_Transfusion Blood Transfusions Transfusion, Blood Transfusions, Blood http://purl.bioontology.org/ontology/MESH/D001803 The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusion peo2:Blood_Transfusion_in_life-time Blood Transfusion in life-time peo2:Blood_Transfusion_in_present_pregnancy Blood transfusion in present pregnancy peo2:Blood_cell Blood cell (cell) http://purl.bioontology.org/ontology/SNOMEDCT/63370004 Blood cell peo2:Blood_coagulation_disorder Bleeding diathesis Bleeding disorder Bleeding tendency Blood clotting disorder Blood coagulation disorder (disorder) Clotting disorder Coagulation disorder Coagulopathy Disorder of haemostasis Disorder of hemostasis Blood coagulation disorder peo2:Blood_pressure_at_first_visit Blood pressure at first booking Blood pressure at first visit peo2:Blood_pressure_finding Blood pressure finding (finding) http://purl.bioontology.org/ontology/SNOMEDCT/392570002 Blood pressure finding peo2:Blood_test Blood test (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/396550006 Blood test peo2:Blue-collar_worker http://en.wikipedia.org/wiki/Blue-collar_worker Blue-collar worker peo2:Body_height_measure Body height Body height measure (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/50373000 Body height measure peo2:Body_mass_index BMI - Body mass index Body mass index (observable entity) Quetelet index Weight: body mass http://purl.bioontology.org/ontology/SNOMEDCT/60621009 Body mass index peo2:Body_measure Body measure (observable entity) Body measurements http://purl.bioontology.org/ontology/SNOMEDCT/248326004 Body measure peo2:Body_weight_measure Body weight measure (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/363808001 Body weight measure peo2:Borderline_poverty_status Borderline poverty (economic status) Borderline poverty (economic status) (social concept) Poverty line status http://purl.bioontology.org/ontology/SNOMEDCT/9629004 Borderline poverty status peo2:Born_from_pre-eclamptic_mother Born from pre-eclamptic mother peo2:Bowman_Capsule Bowman's Capsule Bowmans Capsule Capsule, Bowman Capsule, Bowman's http://purl.bioontology.org/ontology/MESH/D050476 A double-walled epithelial capsule that is the bulbous closed proximal end of the kidney tubular system. It surrounds the cluster of convoluted capillaries of KIDNEY GLOMERULUS and is continuous with the convoluted PROXIMAL KIDNEY TUBULE. Bowman Capsule peo2:Brain_Diseases Brain Disease Brain Disorder Brain Disorders CNS Disorder, Intracranial CNS Disorders, Intracranial Central Nervous System Disorders, Intracranial Central Nervous System Intracranial Disorders Encephalon Disease Encephalon Diseases Intracranial CNS Disorder Intracranial CNS Disorders Intracranial Central Nervous System Disorders http://purl.bioontology.org/ontology/MESH/D001927 Brain Diseases peo2:C10AA_HMG_CoA_reductase_inhibitor C10AA:HMG CoA reductase inhibitors http://purl.obolibrary.org/obo/CHEBI_35664 C10AA:HMG CoA reductase inhibitor peo2:C_H_-_Chronic_disease Chronic disease (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/27624003 C / H - Chronic disease peo2:C_H_-_Mental_disorder Clinical history of mental disorder http://purl.bioontology.org/ontology/SNOMEDCT/74732009 C / H - Mental disorder peo2:Calcium_release http://purl.org/obo/owl/GO#GO_0015278 AD591 Calcium release peo2:Calcium_supplement Calcium supplement (substance) http://purl.bioontology.org/ontology/SNOMEDCT/438581000124107 Calcium supplement peo2:Cannabis_abuse Cannabis abuse peo2:Capillary_lumens Capillary lumens peo2:Capillary_space Capillary space peo2:Cardiac_fibrosis http://purl.bioontology.org/ontology/OMIM/MTHU034875 Cardiac fibrosis peo2:Cardiac_output CO - Cardiac output Cardiac output (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/82799009 Cardiac output peo2:Cardiac_preload Cardiac preload peo2:Cardiac_ventricular_structure Cardiac ventricle Cardiac ventricular structure (body structure) Ventricle http://purl.bioontology.org/ontology/SNOMEDCT/21814001 Cardiac ventricular structure peo2:Cardiomegaly Cardiac Hypertrophy Enlarged Heart Enlargement, Heart Heart Enlargement Heart Hypertrophy Heart, Enlarged http://purl.bioontology.org/ontology/MESH/D006332 Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix. Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES. Cardiomegaly peo2:Cardiomyocyte_death Cardiomyocyte death peo2:Cardioprotection Cardioprotection peo2:Cardiotocography Antepartum CTG CTG, Antepartum Cardiotocograms Cardiotocography, External Cardiotocography, Internal Electronic Fetal Monitoring External Cardiotocography External Fetal Monitoring Fetal Monitoring, Electronic Fetal Monitoring, External Fetal Monitoring, Internal Internal Cardiotocography Internal Fetal Monitoring Monitoring, Electronic Fetal Monitoring, External Fetal Monitoring, Internal Fetal http://purl.bioontology.org/ontology/MESH/D015148 Monitoring of FETAL HEART frequency before birth in order to assess impending prematurity in relation to the pattern or intensity of antepartum UTERINE CONTRACTION. Cardiotocography peo2:Case_control_study Case control study peo2:Case_fatality_rate AD302 Case fatality rate peo2:Cell_invasion Cell invasion peo2:Cell_treatment Cell treatment models AD644 Cell treatment model peo2:Cellular_uptake AD482 Cellular uptake peo2:Cerebral_blood_flow CBF - Cerebral blood flow Cerebral blood flow (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/250847003 Cerebral blood flow peo2:Cerebral_hyperperfusion_syndrome http://purl.bioontology.org/ontology/MEDDRA/10064730 Cerebral hyperperfusion syndrome peo2:Cerebral_palsy CP - Cerebral palsy Cerebral palsy (CP) Cerebral palsy (disorder) Congenital cerebral palsy Infantile cerebral palsy http://purl.bioontology.org/ontology/SNOMEDCT/128188000 A permanent disorder of the development of movement, posture and motor function, causing activity limitation, caused by non-progressive disturbances in the developing fetal or infant brain. Cerebral palsy peo2:Cerebral_perfusion_pressure CPP Cerebral perfusion pressure peo2:Cerebrovascular_Disorders Brain Vascular Disorder Brain Vascular Disorders Cerebrovascular Disorder Cerebrovascular Insufficiencies Cerebrovascular Insufficiency Cerebrovascular Occlusion Cerebrovascular Occlusions Insufficiencies, Cerebrovascular Insufficiency, Cerebrovascular Intracranial Vascular Disease Intracranial Vascular Diseases Intracranial Vascular Disorder Intracranial Vascular Disorders Occlusion, Cerebrovascular Occlusions, Cerebrovascular Vascular Disease, Intracranial Vascular Diseases, Intracranial Vascular Disorder, Brain Vascular Disorder, Intracranial Vascular Disorders, Brain Vascular Disorders, Intracranial Cerebrovascular Disorders peo2:Cerebrovascular_accident CVA - Cerebrovascular accident Cerebrovascular accident (disorder) Cerebrovascular stroke Stroke http://purl.bioontology.org/ontology/SNOMEDCT/230690007 Cerebrovascular accident peo2:Cesarean_section CS - Caesarean section CS - Cesarean section Caesarean section Cesarean section (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/11466000 Cesarean section peo2:Change_of_partner Change of partner peo2:Chemical_exposure http://purl.bioontology.org/ontology/MEDDRA/10068154 Chemical exposure peo2:Cholestrol_reducing_drugs http://www.omnimedicalsearch.com/conditions-diseases/alzheimers-disease-treatment-prevention.html Cholesterol reducing drugs anticholesteremic drug anticholesteremic drugs http://purl.obolibrary.org/obo/CHEBI_35821 AD021 Agents which reduce cholesterol levels in the body. Cholesterol reducing drug peo2:Chorioallantoic_placenta Chorioallantoic placenta (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/75428007 Chorioallantoic placenta peo2:Chorioamnionitis Chorioamnionitis (disorder) Membranitis http://purl.bioontology.org/ontology/SNOMEDCT/11612004 Chorioamnionitis peo2:Chorionic_villi_structure Chorionic villi Chorionic villi structure (body structure) http://purl.bioontology.org/ontology/SNOMEDCT/2049008 Chorionic villi structure peo2:Chronic_active_hepatitis http://purl.bioontology.org/ontology/OMIM/MTHU012239 Chronic active hepatitis peo2:Chronic_arthritis Chronic arthritis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/35908007 Chronic arthritis peo2:Chronic_hypertension_in_obstetric_context Chronic hypertension in obstetric context (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/8762007 Chronic hypertension in obstetric context peo2:Circulating Circulating (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/65929005 Circulating peo2:Climate Climates http://purl.bioontology.org/ontology/MESH/D002980 The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Climate peo2:Clinical_situation Clinical situation peo2:Closed_populations_ AD313 Closed populations peo2:Coagulation_factor_I Coagulation factor I (substance) Fibrinogen http://purl.bioontology.org/ontology/SNOMEDCT/23295004 Coagulation factor I peo2:Coagulation_protein Coagulation protein (substance) http://purl.bioontology.org/ontology/SNOMEDCT/116181003 Coagulation protein peo2:Cocaine_abuse Cocaine abuse peo2:Codeine_abuse Codeine abuse peo2:Coenzyme_Q10 Coenzyme Q10 (product) Ubidecarenone Ubiquinone http://purl.bioontology.org/ontology/SNOMEDCT/412130008 Coenzyme Q10 peo2:Cohort_effect cohort AD259 Cohort effect peo2:Colitis Colitis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/64226004 Colitis peo2:Collagen Avicon Avitene Collagen Felt Collagen Fleece Collagen Hemostat, Microfibril Collagenfleece Collagens Collastat Dermodress Microfibril Collagen Hemostat Pangen Zyderm alpha Collagen alpha-Collagen http://purl.bioontology.org/ontology/MESH/D003094 A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH). A topical hemostatic agent prepared from collagen. Collagen peo2:Collagen_matrix Collagen matrix peo2:Collateral_flow_index CFI Collateral flow index peo2:Complementry_health_approaches Complementary health approaches AD084 classification?? Complementary health approach peo2:Compression_of_umbilical_cord Compression of umbilical cord (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/79222000 Compression of umbilical cord peo2:Congestive_heart_failure CCF - Congestive cardiac failure CHF - Congestive heart failure Congestive cardiac failure Congestive heart disease Congestive heart failure (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/42343007 Congestive heart failure peo2:Connective_tissue_disease_overlap_syndrome Connective tissue disease overlap syndrome (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/398021003 Connective tissue disease overlap syndrome peo2:Conscious_blood_pressure_control Conscious B.P. control Conscious blood pressure control (regime/therapy) http://purl.bioontology.org/ontology/SNOMEDCT/183413003 Conscious blood pressure control peo2:Coronary_arteriosclerosis Arteriosclerotic heart disease CAD - Coronary artery disease CHD - Coronary heart disease Coronary arteriosclerosis (disorder) Coronary artery disease Coronary heart disease Coronary sclerosis http://purl.bioontology.org/ontology/SNOMEDCT/53741008 Coronary arteriosclerosis peo2:Cough Cough (finding) Finding of cough Observation of cough http://purl.bioontology.org/ontology/SNOMEDCT/49727002 Cough peo2:Country_of_birth Born in - country Country of birth (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/315354004 Country of birth peo2:Craniocerebral_Trauma Craniocerebral Injuries Craniocerebral Injury Craniocerebral Traumas Crushing Skull Injuries Crushing Skull Injury Forehead Trauma Forehead Traumas Frontal Region Trauma Frontal Region Traumas Head Injuries Head Injuries, Minor Head Injuries, Multiple Head Injuries, Open Head Injuries, Superficial Head Injury Head Injury, Minor Head Injury, Multiple Head Injury, Open Head Injury, Superficial Head Trauma Head Traumas Injuries, Craniocerebral Injuries, Head Injuries, Minor Head Injuries, Multiple Head Injuries, Open Head Injuries, Superficial Head Injury, Craniocerebral Injury, Head Injury, Minor Head Injury, Multiple Head Injury, Open Head Injury, Superficial Head Minor Head Injuries Minor Head Injury Multiple Head Injuries Multiple Head Injury Occipital Region Trauma Occipital Region Traumas Occipital Trauma Occipital Traumas Open Head Injuries Open Head Injury Parietal Region Trauma Parietal Region Traumas Region Trauma, Frontal Region Trauma, Occipital Region Trauma, Parietal Region Traumas, Frontal Region Traumas, Occipital Region Traumas, Parietal Skull Injuries, Crushing Skull Injury, Crushing Superficial Head Injuries Superficial Head Injury Temporal Region Trauma Temporal Region Traumas Trauma, Craniocerebral Trauma, Forehead Trauma, Frontal Region Trauma, Head Trauma, Occipital Trauma, Occipital Region Trauma, Parietal Region Trauma, Temporal Region Traumas, Craniocerebral Traumas, Forehead Traumas, Frontal Region Traumas, Head Traumas, Occipital Traumas, Occipital Region Traumas, Parietal Region Traumas, Temporal Region http://purl.bioontology.org/ontology/MESH/D006259 Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage. Craniocerebral Trauma peo2:Crohns_disease CD - Crohn's disease Crohn disease Crohn's disease (disorder) Crohn's regional enteritis Crohns disease Granulomatous enteritis RE - Regional enteritis Regional enteritis http://purl.bioontology.org/ontology/SNOMEDCT/34000006 Crohn's disease peo2:Crude_incidence AD303 Crude incidence peo2:Cumulative_incidence AD304 Cumulative incidence peo2:Cumulative_incidence_rate AD305 Cumulative incidence rate peo2:Current_intake Current intake peo2:Current_pregnancy Current pregnancy peo2:Cytodiagnosis Cytodiagnoses http://purl.bioontology.org/ontology/MESH/D003581 Diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of body fluid. (Stedman, 26th ed) Cytodiagnosis peo2:Cytoprotection Cell Protection Protection, Cell http://purl.bioontology.org/ontology/MESH/D019610 The process by which chemical compounds provide protection to cells against harmful agents. Cytoprotection peo2:Cytotrophoblast_invasion Cytotrophoblast invasion peo2:D-dimer D-dimer (substance) DDimer http://purl.bioontology.org/ontology/SNOMEDCT/25607008 D-dimer peo2:De_acetylations protein amino acid deacetylation AD595 De-acetylation peo2:De_methylation AD596 De-methylation peo2:De_phosphorylation AD603 De-phosphorylation peo2:Decidual_Arteriopathy Decidual Arteriopathy peo2:Decidual_cell Decidual cell peo2:Decidual_lymphocyte Decidual lymphocyte peo2:Delivery_by_vacuum_extraction Delivery by vacuum extraction (procedure) Vacuum extraction Vacuum extraction of fetus Ventouse extraction http://purl.bioontology.org/ontology/SNOMEDCT/61586001 Delivery by vacuum extraction peo2:Dementia Dementia (disorder) Organic dementia http://purl.bioontology.org/ontology/SNOMEDCT/52448006 Dementia peo2:Dengue Breakbone fever Dengue (disorder) Dengue fever http://purl.bioontology.org/ontology/SNOMEDCT/38362002 Dengue peo2:Details_of_education Details of education (observable entity) Education http://purl.bioontology.org/ontology/SNOMEDCT/276031006 Details of education peo2:Developed_Countries Countries, Developed Countries, Industrialized Country, Developed Country, Industrialized Developed Country Developed Nation Developed Nations Industrialized Countries Industrialized Country Industrialized Nation Industrialized Nations Nation, Developed Nation, Industrialized Nations, Developed Nations, Industrialized http://purl.bioontology.org/ontology/MESH/D019049 Countries that have reached a level of economic achievement through an increase of production, per capita income and consumption, and utilization of natural and human resources. Developed Countries peo2:Developmental Developmental (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/278923009 Developmental peo2:Diabetes http://purl.bioontology.org/ontology/MEDDRA/10012594 Diabetes peo2:Diabetic_renal_disease Diabetic nephropathy Diabetic renal disease (disorder) Renal disorder associated with diabetes mellitus http://purl.bioontology.org/ontology/SNOMEDCT/127013003 Diabetic renal disease peo2:Diastolic_blood_pressure DAP - Diastolic arterial pressure DBP - Diastolic blood pressure Diastolic arterial pressure Diastolic blood pressure (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/271650006 Diastolic blood pressure peo2:Diet_poor Diet poor (finding) http://purl.bioontology.org/ontology/SNOMEDCT/310502008 Diet poor peo2:Dimerization http://purl.org/obo/owl/GO#GO_0046983 AD604 Dimerization peo2:Dimers Dimers peo2:Direct_injection_of_sperm_into_cytoplasm_of_the_oocyte DISCO - Direct inject of sperm into cytoplasm of the oocyte Direct injection of sperm into cytoplasm of the oocyte (procedure) ICSI - Intracytoplasmic sperm injection Intracytoplasmic sperm injection http://purl.bioontology.org/ontology/SNOMEDCT/225244002 Direct injection of sperm into cytoplasm of the oocyte peo2:Disorder_of_cardiovascular_system CVD - cardiovascular disease CVS disease - cardiovascular system disease Cardiovascular disease Cardiovascular disorder Cardiovascular system disease Disorder of cardiovascular system (disorder) Disorder of circulatory system Disorder of the circulatory system http://purl.bioontology.org/ontology/SNOMEDCT/49601007 Disorder of cardiovascular system peo2:Disorder_of_fetus_or_newborn Disorder of fetus or newborn (disorder) Disorder of foetus or newborn Fetus and neonate conditions http://purl.bioontology.org/ontology/SNOMEDCT/414025005 Disorder of fetus or newborn peo2:Disorder_of_placenta Disorder of placenta (disorder) Disorder of placenta and placental transfusion http://purl.bioontology.org/ontology/SNOMEDCT/125586008 Disorder of placenta peo2:Doppler_studies Doppler Doppler studies (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/268447006 Doppler studies peo2:Downregulation AD613 Downregulation peo2:Drug_abuse Drug abuse (disorder) Drug abuse peo2:Dura_Mater Falx Cerebelli Dura Mater peo2:Duration_of_dilatation_stage Duration of dilatation stage peo2:Duration_of_formal_education Duration of formal education (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224288002 Duration of formal education peo2:Dyslipidemia Dyslipidaemia Dyslipidemia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/370992007 Dyslipidemia peo2:E_E_ratio E/E' ratio peo2:Earlier_miscarriage Earlier miscarriage peo2:Early_neonatal_death Early neonatal death (event) http://purl.bioontology.org/ontology/SNOMEDCT/391181005 Early neonatal death peo2:Echocardiographic_calcium_score ECS Echocardiographic calcium score peo2:Echocardiography Cardiac US scan Cardiac echo Diagnostic ultrasound of heart Echocardiogram Echocardiographic procedure Echocardiography (procedure) US heart scan US scan of heart Ultrasonography of heart http://purl.bioontology.org/ontology/SNOMEDCT/40701008 Echocardiography peo2:Eclampsia Eclampsia (disorder) Eclamptic toxaemia Eclamptic toxemia Toxaemia with convulsions Toxemia with convulsions http://purl.bioontology.org/ontology/SNOMEDCT/15938005 Eclampsia peo2:Eclamptic_encephalopathy Eclamptic encephalopathy peo2:Economic_independence_status Economically independent (economic status) Economically independent (economic status) (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/113168001 Economic independence status peo2:Economic_status Economic status (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/73831000 Economic status peo2:Edema Edema (morphologic abnormality) Edema - lesion Edematous Oedema Oedema - lesion Oedematous http://purl.bioontology.org/ontology/SNOMEDCT/79654002 Edema peo2:Education_and_schooling_detail Education and schooling Education and schooling detail (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224285004 Education and schooling detail peo2:Education_currently_received Education currently received (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224303005 Education currently received peo2:Education_received_in_the_past Education received in the past (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/224293004 Education received in the past peo2:Educational_achievement Academic achievement Educational achievement (observable entity) Educational qualification Level of educational attainment http://purl.bioontology.org/ontology/SNOMEDCT/105421008 Educational achievement peo2:Educational_level_of_guardian_of_subject Educational level of guardian of subject (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/444028004 Educational level of guardian of subject peo2:Educational_level_of_parent_of_subject Educational level of parent of subject (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/443722004 Educational level of parent of subject peo2:Embryo_Implantation Blastocyst Implantation Blastocyst Implantations Decidual Cell Reaction Decidual Cell Reactions Embryo Implantations Implantation, Blastocyst Implantation, Embryo Implantation, Ovum Implantations, Blastocyst Implantations, Embryo Implantations, Ovum Nidation Nidations Ovum Implantation Ovum Implantations http://purl.bioontology.org/ontology/MESH/D010064 Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage. Embryo Implantation peo2:Embryonic_Development http://purl.bioontology.org/ontology/MESH/D047108 Development, Embryo Development, Embryonic Development, Postnidation Embryo Embryo Development Embryo Development, Post-implantation Embryo Development, Postimplantation Embryo Development, Postnidation Embryo Development, Pre-implantation Embryo Development, Preimplantation Embryogenesis Embryonic Developments Embryonic Programming Embryonic Programmings Post implantation Embryo Development Post-implantation Embryo Development Postimplantation Embryo Development Postnidation Embryo Development Postnidation Embryo Development, Animal Pre implantation Embryo Development Pre-implantation Embryo Development Preimplantation Embryo Development Prenidation Embryo Development, Animal Morphological and physiological development of EMBRYOS. Permanent alteration of tissue structures and functions in the EMBRYO as a result of its environment, either positive or negative. The cellular development between the time of mammalian gamete FERTILIZATION and EMBRYO IMPLANTATION. This represents the development in the FALLOPIAN TUBES. Embryonic Development peo2:Emergency_cesarean_section Emergency caesarean section Emergency cesarean section (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/274130007 Emergency cesarean section peo2:Employment_detail Employment detail (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364703007 Employment detail peo2:Endocrine_cell Endocrine cell (cell) http://purl.bioontology.org/ontology/SNOMEDCT/68233007 Endocrine cell peo2:Endocrine_defects Endocrine defects peo2:Endocrine_disorder http://purl.bioontology.org/ontology/MEDDRA/10014695 Endocrine disorder peo2:Endocytosis plasma membrane invagination vesicle endocytosis http://purl.org/obo/owl/GO#GO_0006897 AD483 Endocytosis is the process by which cells absorb molecules (such as proteins) by engulfing them Endocytosis peo2:Endoplasmic_Reticulum_Stress Endoplasmic Reticulum Stresses Reticulum Stress, Endoplasmic Reticulum Stresses, Endoplasmic Stress, Endoplasmic Reticulum Stresses, Endoplasmic Reticulum http://purl.bioontology.org/ontology/MESH/D059865 Various physiological or molecular disturbances that impair ENDOPLASMIC RETICULUM function. It triggers many responses, including UNFOLDED PROTEIN RESPONSE, which may lead to APOPTOSIS; and AUTOPHAGY. Endoplasmic Reticulum Stress peo2:Endoplasmic_reticulum ER Endoplasmic reticulum (cell structure) http://purl.bioontology.org/ontology/SNOMEDCT/33761008 Endoplasmic reticulum peo2:Endothelial_cell Endothelial cell (cell) http://purl.bioontology.org/ontology/SNOMEDCT/45709008 Endothelial cell peo2:Endothelial_dysfunction http://purl.bioontology.org/ontology/MEDDRA/10048554 Endothelial dysfunction peo2:Endothelial_lining Endothelial lining peo2:Endothelium Endothelial tissue Endothelium (body structure) http://purl.bioontology.org/ontology/SNOMEDCT/27168002 Endothelium peo2:Endothelium-derived_hyperpolarizing_factor EDHF Endothelium-derived hyperpolarizing factor peo2:Energy_metabolism AD592 Energy metabolism peo2:Enlarged_uterus Enlarged uterus (finding) Large uterus Uterine enlargement http://purl.bioontology.org/ontology/SNOMEDCT/198319004 Enlarged uterus peo2:Enoxaparin Enoxaparin peo2:Entire_blood_vessel Blood vessel Entire blood vessel (body structure) http://purl.bioontology.org/ontology/SNOMEDCT/361097006 Entire blood vessel peo2:Entire_cytotrophoblast Cytotrophoblast Entire cytotrophoblast (body structure) http://purl.bioontology.org/ontology/SNOMEDCT/308841008 Entire cytotrophoblast peo2:Entire_endometrium Endometrium Entire endometrium (body structure) Tunica mucosa uteri http://purl.bioontology.org/ontology/SNOMEDCT/278867007 Entire endometrium peo2:Entire_heart Entire heart (body structure) Heart http://purl.bioontology.org/ontology/SNOMEDCT/302509004 Entire heart peo2:Entire_kidney Entire kidney (body structure) Kidney http://purl.bioontology.org/ontology/SNOMEDCT/181414000 Entire kidney peo2:Entire_lymph_node Entire lymph node (body structure) LN - Lymph node Lymph node http://purl.bioontology.org/ontology/SNOMEDCT/181756000 Entire lymph node peo2:Entire_placenta Entire placenta (body structure) Placenta http://purl.bioontology.org/ontology/SNOMEDCT/181455002 Entire placenta peo2:Entire_placental_cotyledon Entire placental cotyledon (body structure) Placental cotyledon http://purl.bioontology.org/ontology/SNOMEDCT/256491001 Entire placental cotyledon peo2:Entire_testis Entire testis (body structure) Testis http://purl.bioontology.org/ontology/SNOMEDCT/181431007 Entire testis peo2:Entire_uterus Entire uterus (body structure) UT - Uterus Uterus Womb http://purl.bioontology.org/ontology/SNOMEDCT/181452004 Entire uterus peo2:Entity_relating_to_environmental_cause Entity relating to environmental cause peo2:Enviornmental_causes Environmental causes environmental factor environmental factors http://www.ebi.ac.uk/efo/EFO_0000469 AD459 Environmental cause peo2:Enviornmental_manipulations Environmental manipulations AD085 Environmental manipulation peo2:Environmental_features Environmental factor Environmental factors Environmental feature Environmental features peo2:Epidural_hemorrhage Epidural hemorrhage peo2:Epigastric_pain Epigastric pain (finding) http://purl.bioontology.org/ontology/SNOMEDCT/79922009 Epigastric pain peo2:Epigenetics AD593 Epigenetics peo2:Epilepsy EP - Epilepsy Epilepsy (disorder) Epileptic attack http://purl.bioontology.org/ontology/SNOMEDCT/84757009 Epilepsy peo2:Episiotomy Episiotomy (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/85548006 Episiotomy peo2:Erythrocyte_production Erythrocyte production, function Erythrocyte production, function (observable entity) Erythropoiesis http://purl.bioontology.org/ontology/SNOMEDCT/69611006 Erythrocyte production peo2:Esophageal_Squamous_Cell_Carcinoma http://purl.bioontology.org/ontology/MESH/C562729 Esophageal Squamous Cell Carcinoma peo2:Estimated_fetal_gestational_age_at_delivery Estimated fetal gestational age at delivery (observable entity) Estimated foetal gestational age at delivery http://purl.bioontology.org/ontology/SNOMEDCT/444135009 Estimated fetal gestational age at delivery peo2:Estrogen_level Estrogen level peo2:Eventual_causes Eventual causes AD445 Eventual cause peo2:Ex-tobacco_user Ex-tobacco user (finding) http://purl.bioontology.org/ontology/SNOMEDCT/702975009 Ex-tobacco user peo2:Exceptionally_large_at_birth Birth weight 4500 grams OR more Exceptionally large at birth (disorder) Fetal giant Hypertrophic baby Macrosomia Macrosomic baby Macrosomic infant http://purl.bioontology.org/ontology/SNOMEDCT/38206000 Exceptionally large at birth peo2:Exocytosis Reverse Pinocytosis vesicle exocytosis http://purl.org/obo/owl/GO#GO_0006887 AD484 Exocytosis is the durable process by which a cell directs the contents of secretory vesicles out of the cell membrane. Exocytosis peo2:Exosome_entry Exosome entry peo2:Exosomes http://purl.bioontology.org/ontology/MESH/D055354 Vesicles secreted from MULTIVESICULAR BODIES into the extracellular environment when the multivesicular bodies fuse with the PLASMA MEMBRANE. Multivesicular bodies are formed from ENDOSOMES when they accumulate vesicles (sometimes referred to as "intraluminal vesicles") from inward budding of the endosome membrane. Exosomes peo2:Extravillous_cytotrophoblast Extravillous cytotrophoblast peo2:FGV_parcentage %FGV FGV parcentage peo2:Family_History Family History risk factors family history http://semanticscience.org/resource/SIO_010060 AD339 Family History peo2:Family_history Family histories http://www.ebi.ac.uk/efo/EFO_0000493 AD446 Family history peo2:Family_history_of_cardiovascular_disease Family history of cardiovascular disease peo2:Family_history_of_diabetes_mellitus Family history of diabetes mellitus peo2:Family_history_of_preeclampsia Family history of preeclampsia peo2:Female_infertility_of_anovulatory_origin Anovular cycle Anovulatory infertility Female infertility of anovulatory origin (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/266609001 Female infertility of anovulatory origin peo2:Fetal_gestational_age Fetal gestational age (observable entity) Length of gestation http://purl.bioontology.org/ontology/SNOMEDCT/57036006 Fetal gestational age peo2:Fetal_growth_restriction FGR - Fetal growth retardation Fetal growth retardation Fetal growth retardation (disorder) IUGR - Intrauterine growth retardation Intrauterine growth retardation Microsomia Microsomic baby Poor fetal growth Poor fetal growth state http://purl.bioontology.org/ontology/SNOMEDCT/22033007 Fetal growth restriction peo2:Fetal_intrapartum_death Foetal intrapartum death Intrapartum fetal death Intrapartum fetal death (event) Intrapartum foetal death http://purl.bioontology.org/ontology/SNOMEDCT/237362003 Fetal intrapartum death peo2:Fetal_lung_maturation Fetal lung maturation peo2:Fetal_observable Fetal observable (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364599001 Fetal observable peo2:Fetal_thrombotic_vasculopathy FTV Fetal thrombotic vasculopathy peo2:Fetal_umbilical_vein_structure Fetal umbilical vein Fetal umbilical vein structure (body structure) Left umbilical vein Umbilical vein http://purl.bioontology.org/ontology/SNOMEDCT/13576009 Fetal umbilical vein structure peo2:Fetus_Organs Fetus Organs peo2:Fetus_with_chromosomal_abnormality Fetus with chromosomal abnormality (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/267253006 Fetus with chromosomal abnormality peo2:Fibrin Fibrin (substance) http://purl.bioontology.org/ontology/SNOMEDCT/113361004 Fibrin peo2:Fibrinogen_measurement Fibrinogen level Fibrinogen measurement (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/250346004 Fibrinogen measurement peo2:Fibrosis_of_Chorionic_Villi Villous Fibrosis Fibrosis of Chorionic Villi peo2:Finding_of_brain Finding of brain peo2:Finding_of_measures_of_cervix Finding of measures of cervix (finding) Observation of measures of cervix http://purl.bioontology.org/ontology/SNOMEDCT/289824002 Finding of measures of cervix peo2:First_trimester 1st trimester First trimester (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255246003 First trimester peo2:Fresh_late_fetal_deaths Fresh late fetal deaths peo2:G_protein_coupled_signal_transduction_pathway Gq/11-coupled signal transduction pathway G protein coupled signal transduction pathway peo2:Gave_up_before_pregnancy Gave up before pregnancy peo2:Gave_up_during_pregnancy Gave up during pregnancy peo2:Genetic_Biomarkers http://www.benthamscience.com/open/tonmedj/article/V002/SI0010TONMEDJ/12TONMEDJ.pdf Genetic Biomarkers AD117 Genetic Biomarker peo2:Genetics Genetics genetic risk factor genetic risk factors AD341 Genotype peo2:Genomic_features Genomic factor Genomic factors Genomic feature Genomic features peo2:Geography Factor, Geographic Factors, Geographic Geographic Factor Geographic Factors Geography, Human Human Geography http://purl.bioontology.org/ontology/MESH/D005843 The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed) Geography peo2:Gestational Gestational (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255402008 Gestational peo2:Gestational_diabetes_mellitus Diabetes mellitus arising in pregnancy GDM GDM - Gestational diabetes mellitus Gestational diabetes Gestational diabetes mellitus (disorder) Maternal gestational diabetes mellitus http://purl.bioontology.org/ontology/SNOMEDCT/11687002 Gestational diabetes mellitus peo2:Gestational_hypertension http://purl.bioontology.org/ontology/MEDDRA/10070538 Gestational hypertension peo2:Gestational_trophoblastic_disease Gestational trophoblastic disease (morphologic abnormality) http://purl.bioontology.org/ontology/SNOMEDCT/609518007 Gestational trophoblastic disease peo2:Gestational_weight_gain GWG Gestational weight gain peo2:Glomerular_dysfunction http://purl.bioontology.org/ontology/OMIM/MTHU031506 Glomerular dysfunction (variable) peo2:Glucose_transport http://purl.org/obo/owl/GO#GO_0015758 AD599 Glucose transport peo2:Glycosylation http://purl.org/obo/owl/GO#GO_0070085 AD605 Glycosylation peo2:Guinea_pig Guinea pig peo2:Gynecological_history Gynaecological history Gynecological history (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/267011001 Gynecological history peo2:HELLP_syndrome HELLP - Syndrome of haemolysis, elevated liver enzymes and low platelet HELLP - Syndrome of hemolysis, elevated liver enzymes and low platelet Haemolysis-elevated liver enzymes-low platelet count syndrome Hemolysis-elevated liver enzymes-low platelet count syndrome Hemolysis-elevated liver enzymes-low platelet count syndrome (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/95605009 HELLP syndrome peo2:HIV AIDS Viruses http://purl.bioontology.org/ontology/MESH/D006678 HIV peo2:Haematological_disorders Hematological disorders http://purl.bioontology.org/ontology/MEDDRA/10018847 Haematological disorders peo2:Haemorrhage_finding Haemorrhage finding peo2:Hazard_ratio AD309 Hazard ratio peo2:Headache Headaches cephalalgia http://purl.org/obo/owl/SYMP#SYMP_0000504 AD039 Headache peo2:Heart_disease Cardiac disorder Cardiopathy Disorder of heart Heart disease (disorder) Morbus cordis http://purl.bioontology.org/ontology/SNOMEDCT/56265001 Heart disease peo2:Heart_failure Cardiac failure Cardiac insufficiency HF - Heart failure Heart failure (disorder) Myocardial failure Weak heart http://purl.bioontology.org/ontology/SNOMEDCT/84114007 Heart failure peo2:Heart_rate Cardiac rate Heart rate (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364075005 Heart rate peo2:Hematopoietic_stem_cell Haematopoietic stem cell Hematopoietic stem cell (cell) http://purl.bioontology.org/ontology/SNOMEDCT/418318001 Hematopoietic stem cell peo2:Hemolysis Haemolysis Hemolysis (attribute) http://purl.bioontology.org/ontology/SNOMEDCT/260882000 Hemolysis peo2:Hemorrhagic_endovasculitis HEV hemorrhagic endovasculitis of the placenta Hemorrhagic endovasculitis peo2:Hemostatic_function Blood clotting Blood coagulation Haemostasis Haemostatic function Hemostasis Hemostatic function (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/74848003 Hemostatic function peo2:Heparin_Low-Molecular-Weight Heparin, Low Molecular Weight LMWH Low Molecular Weight Heparin Low-Molecular-Weight Heparin http://purl.bioontology.org/ontology/MESH/D006495 Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism. Heparin, Low-Molecular-Weight peo2:Hepatic_disease Liver disease http://purl.bioontology.org/ontology/MEDDRA/10019650 Hepatic disease peo2:Hernia Herniated structure Herniated structure (morphologic abnormality) Herniated tissue Herniation http://purl.bioontology.org/ontology/SNOMEDCT/414403008 Hernia peo2:Heroin_abuse Heroin abuse peo2:High_birth_weight High birth weight (disorder) High birth weight baby http://purl.bioontology.org/ontology/SNOMEDCT/276613009 High birth weight peo2:High_physical_activity High physical activity peo2:Higher_education Higher education (finding) http://purl.bioontology.org/ontology/SNOMEDCT/161122005 Higher education peo2:Histmorphological_presents Histmorphological presents peo2:Homeostasis Homeostasis, function Homeostasis, function (observable entity) Homoeostasis http://purl.bioontology.org/ontology/SNOMEDCT/21979002 Homeostasis peo2:Human_chorionic_gonadotropin Chorionic gonadotrophin Chorionic gonadotrophin human Chorionic gonadotropin human HCG HCG - Human chorionic gonadotrophin HCG - Human chorionic gonadotropin Human chorionic gonadotrophin Human chorionic gonadotropin (substance) http://purl.bioontology.org/ontology/SNOMEDCT/59433001 Human chorionic gonadotropin peo2:Hydatidiform_mole Complete hydatidiform mole Hydatid mole Hydatidiform mole, no ICD-O subtype Hydatidiform mole, no International Classification of Diseases for Oncology subtype Hydatidiform mole, no International Classification of Diseases for Oncology subtype (morphologic abnormality) http://purl.bioontology.org/ontology/SNOMEDCT/48430004 Hydatidiform mole peo2:Hydatidiform_mole_benign Hydatid mole Hydatidiform mole Hydatidiform mole, benign (disorder) Molar pregnancy with hydatid mole Molar pregnancy with vesicular mole http://purl.bioontology.org/ontology/SNOMEDCT/417044008 Hydatidiform mole, benign peo2:Hydropic_placenta Hydropic placenta http://purl.obolibrary.org/obo/HP_0011414 Hydropic placenta peo2:Hydrops_fetalis HF - Hydrops fetalis Hydrops fetalis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/276508000 Hydrops fetalis peo2:Hyperandrogenemia Hyperandrogenemia (finding) http://purl.bioontology.org/ontology/SNOMEDCT/371131009 Hyperandrogenemia peo2:Hyperandrogenization_syndrome Hyperandrogenisation syndrome Hyperandrogenism Hyperandrogenization syndrome (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/237793004 Hyperandrogenization syndrome peo2:Hypercoiled_umbilical_cord Hypercoiled umbilical cord peo2:Hyperemesis Hyperemesis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/444673007 Hyperemesis peo2:Hyperglycemia Hyperglycaemia Hyperglycemia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/80394007 Hyperglycemia peo2:Hyperhomocysteinemia Hyperhomocysteinemia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/419503008 Hyperhomocysteinemia peo2:Hyperlipidemia http://purl.bioontology.org/ontology/MEDDRA/10020667 Hyperlipidemia peo2:Hypertension_associated_disorders_of_pregnancy http://purl.bioontology.org/ontology/MEDDRA/10020776 Hypertension associated disorders of pregnancy peo2:Hypertensive_Encephalopathy Encephalopathy, Hypertensive http://purl.bioontology.org/ontology/MESH/D020343 Brain dysfunction or damage resulting from sustained MALIGNANT HYPERTENSION. When BLOOD PRESSURE exceeds the limits of cerebral autoregulation, cerebral blood flow is impaired (BRAIN ISCHEMIA). Clinical manifestations include HEADACHE; NAUSEA; VOMITING; SEIZURES; altered mental status (in some cases progressing to COMA); PAPILLEDEMA; and RETINAL HEMORRHAGE. Hypertensive Encephalopathy peo2:Hypertensive_disorder BP - High blood pressure BP+ - Hypertension Elevated blood pressure HBP - High blood pressure HT - Hypertension HTN - Hypertension High blood pressure High blood pressure disorder Hyperpiesia Hyperpiesis Hypertension Hypertensive disorder, systemic arterial Hypertensive disorder, systemic arterial (disorder) Hypertensive vascular degeneration Hypertensive vascular disease Raised blood pressure Systemic arterial hypertension Hypertensive disorder peo2:Hypoxia http://purl.bioontology.org/ontology/OMIM/MTHU016005 Hypoxia peo2:Hysterectomy Excision procedure on uterus Hysterectomy (procedure) Uterus excision http://purl.bioontology.org/ontology/SNOMEDCT/236886002 Hysterectomy peo2:Image_based_biomarkers R. J. Killiany, T. Gomez-Isla, and T. Gomez-Isla, “Use of structural magnetic resonance imaging to predict who will get Alzheimers disease,” Annals of Neurology, vol. 47, no. 4, pp. 430–439, 2000. C. J. A. Moulin, M. Laine, J. O. Rinne, V. Kaasinen, H. Sipilä, J. Hiltunen, and A. Kangasmäki, “Brain function during multi-trial learning in mild cognitive impairment: a PET activation study,” Brain Research, vol. 1136, no. 1, pp. 132–141, 2007. C. A. Mathis, Y. Wang, D. P. Holt, G.-F. Huang, M. L. Debnath, and W. E. Klunk, “Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents,” Journal of Medicinal Chemistry, vol. 46, no. 13, pp. 2740–2754, 2003. http://www.sage-hindawi.com/journals/ijad/2010/606802/#B18 Image based biomarkers imaging biomarker imaging biomarkers molecular imaging biomarker molecular imaging biomarkers neuroimaging biomarker neuroimaging biomarkers AD118 Image based biomarker peo2:Immunosuppression Immunosuppression (finding) http://purl.bioontology.org/ontology/SNOMEDCT/38013005 Immunosuppression peo2:Immunotolerance Immunotolerance peo2:In_vitro_fertilization IVF In vitro fertilisation In vitro fertilisation procedure In vitro fertilization procedure Test tube baby technique Test tube ovum fertilisation Test tube ovum fertilization Test tube ovum fertilization (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/52637005 In vitro fertilization peo2:Incidence AD301 Incidence peo2:Incidence_density_ratio AD310 Incidence density ratio peo2:Incidence_in_non_exposed AD307 Incidence in non exposed peo2:Incidence_rate AD308 Incidence rate peo2:Indian Indian (racial group) http://purl.bioontology.org/ontology/SNOMEDCT/414481008 Indian peo2:Induced_labour http://purl.bioontology.org/ontology/MEDDRA/10021718 Induced labour peo2:Infection Infection peo2:Infectious_causes Infectious causes infection infections AD455 Infectious cause peo2:Inflammatory_disorder Inflammatory disease Inflammatory disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/128139000 Inflammatory disorder peo2:Inflammatory_markers Inflammatory markers inflammatory biomarker inflammatory biomarkers AD120 Inflammatory marker peo2:Initial_causes Initial causes AD456 Initial cause peo2:Insufficient_endocervical_transformation_zone_component_in_a_cervical_specimen Insufficient endocervical / transformation zone component in a cervical specimen (finding) http://purl.bioontology.org/ontology/SNOMEDCT/373877006 Insufficient endocervical / transformation zone component in a cervical specimen peo2:Insulin Insulin (substance) http://purl.bioontology.org/ontology/SNOMEDCT/67866001 Insulin peo2:Insulin_resistance Insulin Sensitivity Resistance, Insulin Sensitivity, Insulin http://purl.obolibrary.org/obo/HP_0000855 `Increased resistance` (PATO:0001650) towards `insulin` (PRO:000009054), that is, diminished effectiveness of insulin in reducing blood glucose levels. Insulin resistance peo2:Intervillous_blood_space Intervillous blood space peo2:Intracerebral_hemorrhage http://purl.bioontology.org/ontology/OMIM/MTHU036748 Intracerebral hemorrhage peo2:Intracranial_hemorrhage Intracranial haemorrhage Intracranial hemorrhage (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/1386000 Intracranial hemorrhage peo2:Intrapartum Intrapartum (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/276987000 Intrapartum peo2:Intravascular_Coagulation Intravascular Coagulation peo2:Intravillous_hemorrhage Intravillous hemorrhage peo2:Invloving_patient_in_structured_therapeutic_activities AD086 Involving patient in structured therapeutic activities peo2:Iron_supplement Iron supplement (substance) http://purl.bioontology.org/ontology/SNOMEDCT/438641000124100 Iron supplement peo2:Irregularly_used Irregularly used peo2:Ischemia_placental http://purl.bioontology.org/ontology/MEDDRA/10023035 Ischemia placental peo2:Ischemic_heart_disease IHD - Ischaemic heart disease IHD - Ischemic heart disease Ischaemic heart disease Ischemic heart disease (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/414545008 Ischemic heart disease peo2:Ischemic_stroke Ischaemic stroke Ischemic stroke (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/422504002 Ischemic stroke peo2:Kallidin_I Bradykinin Kallidin I (substance) http://purl.bioontology.org/ontology/SNOMEDCT/56448008 Kallidin I peo2:Kidney_disease Disease of kidney Disorder of kidney Kidney disease (disorder) Nephropathy Nephrosis Renal disease Renal disorder http://purl.bioontology.org/ontology/SNOMEDCT/90708001 Kidney disease peo2:LIGHT_Signaling LIGHT Signaling peo2:LVEDP LVEDP peo2:Labyrinth_zone Labyrinth zone peo2:Lack_of_social_support Lack of social support peo2:Large_for_gestational_age http://purl.bioontology.org/ontology/OMIM/MTHU005715 Large for gestational age peo2:Late-preterm Late-preterm peo2:Late_fetal_death Late fetal death peo2:Later_in_life Later in life peo2:Latitude Latitude peo2:Left-sided_unilateral_notching left unilateral notch Left-sided unilateral notching peo2:Left_ventricular_end-diastolic_pressure LVEDP - Left ventricular end-diastolic pressure Left ventricular end-diastolic pressure (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/276781007 Left ventricular end-diastolic pressure peo2:Length_of_gestation_at_birth Gestational age at birth Length of gestation at birth (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/412726003 Duration of the pregnancy Length of gestation at birth peo2:Length_of_gestation_at_time_of_procedure Length of gestation at time of procedure (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/445872007 Length of gestation at time of procedure peo2:Lipid_metabolism lipid metabolism AD600 Lipid metabolism peo2:Lipid_overload Lipid overload peo2:Live_Birth Live Births http://purl.bioontology.org/ontology/MESH/D050498 The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN). Live Birth peo2:Loan_foreclosure_status Foreclosure on loan Loan foreclosure status (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/105578003 Loan foreclosure status peo2:Longitudinal_study Longitudinal study peo2:Low_birthweight http://purl.bioontology.org/ontology/OMIM/MTHU034621 Low birthweight peo2:Low_physical_activity Low physical activity peo2:Lower_class_economic_status Low income status Lower class economic status (social concept) low regional economic status low socio economic status low socio-economic lower socio-economic status poor socio-economic status poverty http://purl.bioontology.org/ontology/SNOMEDCT/36877009 http://purl.obolibrary.org/obo/ExO_0000015 Lower class economic status peo2:Lower_middle_class_economic_status Lower middle class economic status (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/80123004 Lower middle class economic status peo2:Lung_disease http://purl.bioontology.org/ontology/MEDDRA/10051054 Lung disease peo2:Lymphopoiesis http://purl.bioontology.org/ontology/MESH/D038041 Formation of LYMPHOCYTES and PLASMA CELLS from the lymphoid stem cells which develop from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW. These lymphoid stem cells differentiate into T-LYMPHOCYTES; B-LYMPHOCYTES; PLASMA CELLS; or NK-cells (KILLER CELLS, NATURAL) depending on the organ or tissues (LYMPHOID TISSUE) to which they migrate. Lymphopoiesis peo2:Macerated_stillbirth Macerated stillbirth (finding) http://purl.bioontology.org/ontology/SNOMEDCT/237366000 Macerated stillbirth peo2:Magnesium_sulfate Epsom salt Magnesium sulfate (product) Magnesium sulphate http://purl.bioontology.org/ontology/SNOMEDCT/37400007 Magnesium sulfate peo2:Maintaining_overall_health_through_regular_medical_care__diet__and_exercise AD087 Maintaining overall health through regular medical care, diet, and exercise peo2:Malaria http://purl.bioontology.org/ontology/SNOMEDCT/61462000 Malaria Malaria (disorder) Paludism Plasmodiosis peo2:Malignant_tumor_of_breast Breast cancer CA - Breast cancer Malignant tumor of breast (disorder) Malignant tumour of breast http://purl.bioontology.org/ontology/SNOMEDCT/254837009 Malignant tumor of breast peo2:Malignant_tumor_of_lung CA - Lung cancer Malignant tumor of lung (disorder) Malignant tumour of lung http://purl.bioontology.org/ontology/SNOMEDCT/363358000 Malignant tumor of lung peo2:Malnourishment Malnourishment peo2:Mann_Whitney_test Mann-Whitney Mann-Whitney tests from manual annotation of text corpus Mann-Whitney test peo2:Marital_status Marital status (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/125680007 Marital status peo2:Massive_perivillous_fibrin_deposition Massive perivillous fibrin deposition peo2:Maternal_Organs Maternal Organs peo2:Maternal_death Maternal death (event) Maternal mortality http://purl.bioontology.org/ontology/SNOMEDCT/59283008 Maternal death peo2:Maternal_floor_infarction MFI Maternal floor infarction peo2:Maternal_mortality_rate Maternal mortality rate peo2:Maternal_near_miss Maternal near miss peo2:Maternal_tobacco_use Maternal tobacco use (finding) http://purl.bioontology.org/ontology/SNOMEDCT/427189007 Maternal tobacco use peo2:Meconium Meconiums http://purl.bioontology.org/ontology/MESH/D008470 The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn. Meconium peo2:Medical_history Clinical history http://www.ebi.ac.uk/efo/EFO_0000352 Medical history peo2:Mental_disorder Mental disease Mental disorder (disorder) Mental health disorder Mental illness Psychiatric disorder Psychiatric illness http://purl.bioontology.org/ontology/SNOMEDCT/74732009 Mental disorder peo2:Metabolic_Markers http://www.benthamscience.com/open/tonmedj/article/V002/SI0010TONMEDJ/12TONMEDJ.pdf Metabolic Markers metabolic biomarker metabolic biomarkers AD132 Metabolic Marker peo2:Metabolic_disease MD - Metabolic disorders Metabolic disease (disorder) Metabolic disorder http://purl.bioontology.org/ontology/SNOMEDCT/75934005 Metabolic disease peo2:Metabolic_encephalopathy Metabolic brain syndrome Metabolic encephalopathy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/50122000 Metabolic encephalopathy peo2:Metabolic_syndrome_X Dysmetabolic syndrome X Insulin resistance syndrome Metabolic syndrome Metabolic syndrome X (disorder) Reaven's syndrome http://purl.bioontology.org/ontology/SNOMEDCT/237602007 Metabolic syndrome X peo2:Methadone_abuse Methadone abuse peo2:Methamphetamine_abuse Methamphetamine abuse peo2:Methylation http://purl.org/obo/owl/GO#GO_0032259 AD597 Methylation peo2:Microvascular_Markers http://www.benthamscience.com/open/tonmedj/article/V002/SI0010TONMEDJ/12TONMEDJ.pdf Microvascular Markers microvascular biomarker microvascular biomarkers AD135 Microvascular Marker peo2:Microvillus_plasma_membrane Microvillus plasma membrane peo2:Mid_pregnancy Mid pregnancy peo2:Middle_cerebral_artery MCA Middle cerebral artery peo2:Middle_class_economic_status Middle class economic status (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/22575004 Middle class economic status peo2:Miscarriage Miscarriage (disorder) Spontaneous abortion Vaginal expulsion of fetus Vaginal expulsion of product of conception http://purl.bioontology.org/ontology/SNOMEDCT/17369002 Miscarriage peo2:Miscarriage_in_first_trimester Miscarriage in first trimester (disorder) Spontaneous abortion in first trimester http://purl.bioontology.org/ontology/SNOMEDCT/19169002 Miscarriage in first trimester peo2:Miscarriage_in_second_trimester Miscarriage in second trimester (disorder) Spontaneous abortion in second trimester http://purl.bioontology.org/ontology/SNOMEDCT/85116003 Miscarriage in second trimester peo2:Mitochondria_transport http://purl.org/obo/owl/GO#GO_0006839 AD485 Mitochondria transport peo2:Mixed_collagen_vascular_disease MCTD - Mixed connective tissue disease Mixed collagen vascular disease (disorder) Mixed connective tissue disease Sharp's syndrome http://purl.bioontology.org/ontology/SNOMEDCT/398049005 Mixed collagen vascular disease peo2:Molecular_rolls Molecular rolls peo2:Morphine_abuse Morphine abuse peo2:Morphologically_abnormal_structure Abnormal tissue appearance Lesion Morphologically abnormal structure (morphologic abnormality) http://purl.bioontology.org/ontology/SNOMEDCT/49755003 Morphologically abnormal structure peo2:Multiorgan_failure http://purl.bioontology.org/ontology/MEDDRA/10028162 Multiorgan failure peo2:Multiparous Multiparous (finding) http://purl.bioontology.org/ontology/SNOMEDCT/28079008 Multiparous peo2:Multiple_pregnancy Multiple pregnancy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/16356006 Multiple pregnancy peo2:Multivitamins http://purl.bioontology.org/ontology/NDFRT/N0000020121 Multivitamins peo2:Myometrial_structure Myometrial structure (body structure) Myometrium http://purl.bioontology.org/ontology/SNOMEDCT/27232003 Myometrial structure peo2:N-Acetyl-Cysteine NAC N-Acetyl-Cysteine peo2:NFKB NFKB peo2:NS1619 A selective large conductance calcium activated potassium channel activator NS1619 peo2:NS309 A Ca2+-activated IK/SK potassium channel activator NS309 peo2:Neonatal_disorder Neonatal disease Neonatal disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/22925008 Neonatal disorder peo2:Neonatal_mortality_rate Neonatal mortality rate peo2:Neonate_observable Neonate observable (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364585000 Neonate observable peo2:Neoplasm_by_body_site Neoplasm by body site (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/127331007 Neoplasm by body site peo2:Neurodegeneration http://purl.bioontology.org/ontology/OMIM/MTHU007383 Neurodegeneration peo2:Neurodevelopment Neurodevelopment peo2:Neurological_dysfunction Neurological dysfunction peo2:Never_intake_alcohol Never intake alcohol peo2:Never_used_tobacco Never used tobacco (finding) http://purl.bioontology.org/ontology/SNOMEDCT/702979003 Never used tobacco peo2:Newborn_death Neonatal death Newborn death (event) http://purl.bioontology.org/ontology/SNOMEDCT/276506001 Newborn death peo2:Nitrosylation protein amino acid nitrosylation http://purl.org/obo/owl/GO#GO_0017014 AD606 Nitrosylation peo2:Non-HDL-_C Non-HDL- C peo2:Nonreassuring_fetal_status Fetal distress Fetal distress (finding) Foetal distress Nonreassuring foetal status http://purl.bioontology.org/ontology/SNOMEDCT/130955003 Nonreassuring fetal status peo2:Nonsteroidal_Antiinflamatory_drugs http://www.omnimedicalsearch.com/conditions-diseases/alzheimers-disease-treatment-prevention.html NAIDs NSAID NSAID's NSAIMS Non steroidal antiinflamatory agents Non steroidal antiinflamatory analgesics Non steroidal antiinflamatory medicines Nonsteroidal Antiinflamatory drugs non-steroidal anti-inflammatory drug non-steroidal anti-inflammatory drugs nonsteroidal anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35475 AD047 Nonsteroidal anti-inflammatory drugs, are drugs with analgesic and antipyretic (fever-reducing) effects and which have, in higher doses, anti-inflammatory effects. Nonsteroidal Antiinflamatory drug peo2:Normal_functions_of_organs Normal functions of organs peo2:Nulliparous Nulliparous (finding) http://purl.bioontology.org/ontology/SNOMEDCT/102877006 Nulliparous peo2:Nutritional_condition Nutritional condition peo2:Obesity Adiposis Adiposity Obesity (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/414916001 BMI over 30 Obesity peo2:Obstetric_complications Obstetric labor complication Obstetric complications peo2:Obstetric_umbilical_artery_Doppler Doppler ultrasound scan of umbilical artery Obstetric umbilical artery Doppler (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/427623005 Obstetric umbilical artery Doppler peo2:Obstetric_uterine_artery_Doppler Doppler ultrasound scan of uterine artery Obstetric uterine artery Doppler (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/426295007 Obstetric uterine artery Doppler peo2:Obstructed_labor Obstructed labor (finding) Obstructed labour http://purl.bioontology.org/ontology/SNOMEDCT/199746004 Obstructed labor peo2:Odds_ratio AD316 Odds ratio peo2:Oligohydramnios Deficient liquor Oligohydramnios (disorder) Reduced liquor volume Scanty liquor http://purl.bioontology.org/ontology/SNOMEDCT/59566000 Oligohydramnios peo2:Oliguria Oligouria Oliguria (finding) Passes too little urine Urine output low http://purl.bioontology.org/ontology/SNOMEDCT/83128009 Oliguria peo2:Omental_Vessels Omental Vessels peo2:Open_populations AD314 Open populations peo2:Organelle Organelle (cell structure) Organelle structure http://purl.bioontology.org/ontology/SNOMEDCT/116194001 Organelle peo2:Ovarian_Diseases Disease, Ovarian Diseases, Ovarian Ovarian Disease http://purl.bioontology.org/ontology/MESH/D010049 Ovarian Diseases peo2:Ovarian_hyperstimulation_syndrome Ovarian hyperstimulation syndrome (disorder) Secondary Meig's syndrome http://purl.bioontology.org/ontology/SNOMEDCT/129635004 Ovarian hyperstimulation syndrome peo2:Overweight Overweight (finding) Patient overweight http://purl.bioontology.org/ontology/SNOMEDCT/238131007 Overweight peo2:Oxidative_stress oxidative damage AD601 Oxidative stress peo2:Pain Dolor Pain (finding) Pain observations Painful Part hurts http://purl.bioontology.org/ontology/SNOMEDCT/22253000 Pain peo2:Paralysis_from_birth_trauma Paralysis from birth trauma (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/371129000 Paralysis from birth trauma peo2:Parents_country_of_birth Parents’ country of birth peo2:Parity Parity (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364325004 Parity peo2:Partial_Thromboplastin_Time Activated Partial Thromboplastin Time Cephalin Kaolin Coagulation Time Cephalin-Kaolin Coagulation Time Coagulation Time, Cephalin Kaolin Coagulation Time, Cephalin-Kaolin Coagulation Time, Kaolin-Cephalin Kaolin Cephalin Coagulation Time Kaolin-Cephalin Coagulation Time Thromboplastin Time, Partial http://purl.bioontology.org/ontology/MESH/D010314 The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy. Partial Thromboplastin Time peo2:Passive_smoker ETS - Exposed to tobacco smoke Exposed to environmental tobacco smoke Exposed to second hand tobacco smoke Exposed to tobacco smoke Involuntary smoker Passive smoker (finding) http://purl.bioontology.org/ontology/SNOMEDCT/43381005 Passive smoker peo2:Pathway Pathway peo2:Peptide Peptide peo2:Perfluoroalkylated_acids_and_related_compounds PFAS Perfluoroalkylated acids and related compounds peo2:Perfluorohexanesulfonic_acid PFHS cpd PFHxS perfluorohexanesulfonate http://purl.bioontology.org/ontology/MESH/C471071 Perfluorohexanesulfonic acid peo2:Periconceptional Periconceptional peo2:Perinatal_asphyxia Perinatal asphyxia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/281578009 Perinatal asphyxia peo2:Peripheral_vascular Peripheral vascular peo2:Peripheral_vascular_disease PVD-peripheral vascular disease Peripheral vascular disease (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/400047006 Peripheral vascular disease peo2:Person_time_incidence_rate AD311 Person time incidence rate peo2:Phenotypic_functions Phenotypic functions peo2:Phosphorylation http://purl.org/obo/owl/GO#GO_0016310 AD607 Phosphorylation peo2:Physically_active Physically active (finding) http://purl.bioontology.org/ontology/SNOMEDCT/228447005 Physically active peo2:Physiological_stress Physiological stress (attribute) http://purl.bioontology.org/ontology/SNOMEDCT/260759008 Physiological stress peo2:Physiological_test http://purl.bioontology.org/ontology/HL7/C1551303 Physiological test peo2:Pituitary_apoplexy Pituitary apoplexy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/237701005 Pituitary apoplexy peo2:Placebo_controlled_study Placebo controlled studies placebo-controlled studies placebo-controlled study placebo-controlled trial placebo-controlled trials Placebo controlled study peo2:Placenta_previa PP - Placenta praevia PP - Placenta previa Placenta praevia Placenta previa (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/36813001 Placenta previa peo2:Placental_Apoptosis Placental Apoptosis peo2:Placental_Hematoma Subchorionic Hematoma Subchorionic Hemorrhage Placental Hematoma peo2:Placental_Villous_Explant Placental Villous Explant peo2:Placental_abruption Ablatio placentae Abruptio placentae Placental abruption (disorder) Premature detachment of normally implanted placenta Premature detachment of placenta Premature separation of placenta http://purl.bioontology.org/ontology/SNOMEDCT/415105001 Placental abruption peo2:Placental_cell Placental cell peo2:Placental_damage Placental damage peo2:Placental_edema Placental edema peo2:Placental_explants Placental explants peo2:Placental_finding Placental details Placental finding (finding) http://purl.bioontology.org/ontology/SNOMEDCT/169952004 Placental finding peo2:Placental_implantation Placental implantation peo2:Placental_infarct Placental infarct (disorder) Placental infarction http://purl.bioontology.org/ontology/SNOMEDCT/268585006 Placental infarct peo2:Placental_microvesicles STBM Syncytiotrophoblast microvesicles Placental microvesicles peo2:Placental_perfusion perfusion Placental perfusion peo2:Placental_remodeling Placental remodeling peo2:Placental_uterine_interface Placental uterine interface peo2:Placental_vascularization Placental vascularization peo2:Placentation Placentation, function Placentation, function (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/112067000 Placentation peo2:Plasma Plasma (substance) http://purl.bioontology.org/ontology/SNOMEDCT/50863008 Plasma peo2:Plasma_cell Plasma cell (cell) Plasmacyte Plasmocyte http://purl.bioontology.org/ontology/SNOMEDCT/113335003 Plasma cell peo2:Platelet PLT - Platelet PLT - Platelets Platelet (cell structure) Platelets Thrombocyte http://purl.bioontology.org/ontology/SNOMEDCT/16378004 Platelet peo2:Platelet_active_drugs Platelet active drugs peo2:Platelet_count Platelet count (procedure) Platelet count - observation Plt - Platelet count http://purl.bioontology.org/ontology/SNOMEDCT/61928009 Platelet count peo2:Platelet_count_below_reference_range Platelet count below reference range (finding) Thrombocytopenia http://purl.bioontology.org/ontology/SNOMEDCT/415116008 Platelet count below reference range peo2:Polycystic_ovaries Cystic disease of ovaries Multicystic ovaries PCO - Polycystic ovaries PCOD - Polycystic ovarian disease PCOS - Polycystic ovarian syndrome Polycystic ovarian disease Polycystic ovarian syndrome Polycystic ovaries (disorder) Polycystic ovary syndrome Sclerocystic ovary syndrome Stein-Leventhal syndrome http://purl.bioontology.org/ontology/SNOMEDCT/69878008 Polycystic ovaries peo2:Polyhydramnios Excessive liquor Hydramnios Polyhydramnios (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/86203003 Polyhydramnios peo2:Poor_education Poor education (finding) http://purl.bioontology.org/ontology/SNOMEDCT/105422001 Poor education peo2:Poor_neonatal_condition Poor neonatal condition peo2:Poor_placental_development Poor placental development peo2:Poor_uteroplacental_perfusion Poor uteroplacental perfusion peo2:Populations Populations AD312 Population peo2:Post_translational_modification PTM Post translational modifications post-translational amino acid modification post-translational amino acid modifications post-translational modification post-translational modifications posttranslational amino acid modification posttranslational amino acid modifications posttranslational modification posttranslational modifications posttranslational protein modification posttranslational protein modifications http://purl.org/obo/owl/GO#GO_0043687 AD602 Post translational modification peo2:Postmenopausal_state Postmenopausal state peo2:Postnatal Postnatal (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/263844007 Postnatal peo2:Postneonatal_death Postneonatal death (event) http://purl.bioontology.org/ontology/SNOMEDCT/391100008 Death of an infant after 28 days of age and before 1 year of age Postneonatal death peo2:Postpartum Postpartum (qualifier value) Puerperal http://purl.bioontology.org/ontology/SNOMEDCT/255410009 Postpartum peo2:Postpartum_Infections Postpartum Infections peo2:Postpartum_hemorrhage Bleeding postpartum Haemorrhage after delivery of foetus Hemorrhage after delivery of fetus PPH - Postpartum haemorrhage PPH - Postpartum hemorrhage Postpartum haemorrhage Postpartum hemorrhage (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/47821001 Postpartum hemorrhage peo2:Postpartum_state Postpartum period Postpartum state (finding) Puerperium http://purl.bioontology.org/ontology/SNOMEDCT/86569001 Postpartum state peo2:Potassium_transport K+ conductance potassium transport http://purl.org/obo/owl/GO#GO_0006813 AD608 Potassium transport peo2:Pre-eclampsia EPH - Edema, proteinuria and hypertension of pregnancy EPH - Oedema, proteinuria and hypertension of pregnancy PE - Pre-eclampsia PET - Pre-eclamptic toxaemia PET - Pre-eclamptic toxemia Pre-eclampsia (disorder) Pre-eclamptic toxaemia Pre-eclamptic toxemia Preeclampsia Proteinuric hypertension of pregnancy http://purl.bioontology.org/ontology/SNOMEDCT/398254007 Pre-eclampsia peo2:Pre-gestational_period Pre-gestational period peo2:Precursors Precursors peo2:Pregnancy Gravidity Pregnancy peo2:Pregnancy-induced_hypertension GH - Gestational hypertension Gestational hypertension Hypertension complicating childbirth Hypertension complicating pregnancy Hypertension complicating pregnancy, childbirth AND/OR puerperium Hypertension in the obstetric context Hypertension induced by pregnancy PIH - Pregnancy-induced hypertension Pregnancy-induced hypertension (disorder) Unspecified hypertension complicating pregnancy, childbirth or puerperium http://purl.bioontology.org/ontology/SNOMEDCT/48194001 Pregnancy-induced hypertension peo2:Pregnancy_Ectopic Ectopic Pregnancies Ectopic Pregnancy Extrauterine Pregnancies Extrauterine Pregnancy Pregnancies, Ectopic Pregnancies, Extrauterine Pregnancy, Extrauterine http://purl.bioontology.org/ontology/MESH/D011271 A potentially life-threatening condition in which EMBRYO IMPLANTATION occurs outside the cavity of the UTERUS. Most ectopic pregnancies (>96%) occur in the FALLOPIAN TUBES, known as TUBAL PREGNANCY. They can be in other locations, such as UTERINE CERVIX; OVARY; and abdominal cavity (PREGNANCY, ABDOMINAL). Pregnancy, Ectopic peo2:Pregnancy_Outcome Outcome, Pregnancy Outcomes, Pregnancy Pregnancy Outcomes http://purl.bioontology.org/ontology/MESH/D011256 Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO. Pregnancy Outcome peo2:Pregnancy_observable Pregnancy observable (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/364320009 Pregnancy observable peo2:Pregnancy_termination_care Pregnancy termination care (regime/therapy) http://purl.bioontology.org/ontology/SNOMEDCT/386394001 Pregnancy termination care peo2:Pregnancy_test_urine http://purl.bioontology.org/ontology/MEDDRA/10036576 Pregnancy test urine peo2:Pregnancy_time_period Pregnancy time period (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/307159006 Pregnancy time period peo2:Premature_Birth Birth, Premature Birth, Preterm Births, Premature Births, Preterm Premature Births Preterm Birth Preterm Births http://purl.bioontology.org/ontology/MESH/D047928 CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION). Premature Birth peo2:Prenatal_Nutritional_Physiological_Phenomena Nutrition During Pregnancy Nutrition Physiology, Prenatal Nutrition, Pregnancy Nutritional Physiology, Prenatal Physiology, Prenatal Nutrition Physiology, Prenatal Nutritional Pregnancy Nutrition Prenatal Nutrition Physiology Prenatal Nutritional Physiological Phenomenon Prenatal Nutritional Physiology http://purl.bioontology.org/ontology/MESH/D039401 Nutrition of FEMALE during PREGNANCY. Prenatal Nutritional Physiological Phenomena peo2:Prepregnancy_BMI pre-gestational BMI prepregnancy body mass index Prepregnancy BMI peo2:Previous_HELLP_syndrom Previous HELLP syndrome peo2:Previous_IUGR Previous IUGR peo2:Previous_SGA Previous SGA peo2:Previous_eclampsia Previous eclampsia peo2:Previous_gestational_diabetes Previous gestational diabetes peo2:Previous_gestational_hypertension Previous gestational hypertension peo2:Previous_induced_abortion Previous induced abortion peo2:Previous_miscarriage Previous miscarriage peo2:Previous_neonatal_death Previous neonatal death peo2:Previous_preeclampsia Previous preeclampsia peo2:Previous_pregnancies Previous pregnancies (finding) http://purl.bioontology.org/ontology/SNOMEDCT/127362006 Previous pregnancies peo2:Previous_preterm_delivery Previous preterm delivery peo2:Previous_stillbirth Previous stillbirth peo2:Pro-inflammatory_mediators Pro-inflammatory mediators peo2:Pro-inflammatory_responses Pro-inflammatory responses peo2:Prolonged_labor Long labor Long labour Prolonged labor (disorder) Prolonged labour http://purl.bioontology.org/ontology/SNOMEDCT/53443007 Prolonged labor peo2:Protein_aggregation AD609 Protein aggregation peo2:Protein_degradation protein breakdown protein catabolism protein degradation proteolytic process http://purl.org/obo/owl/GO#GO_0030163 AD610 Protein degradation peo2:Protein_misfolding Protein misfoldings AD611 Protein misfolding peo2:Proteinuria Abnormal presence of protein in urine Proteinuria (finding) http://purl.bioontology.org/ontology/SNOMEDCT/29738008 Proteinuria peo2:Prothrombin_time PT - Prothrombin time PT assay Prothrombin time (procedure) Protime Quick one stage prothrombin time http://purl.bioontology.org/ontology/SNOMEDCT/396451008 Prothrombin time peo2:Prothrombotic_state Prothrombotic state peo2:Psoriasis_with_arthropathy PA - Psoriatic arthritis PsA - Psoriatic arthritis Psoriasis with arthropathy (disorder) Psoriatic arthritis Psoriatic arthropathy http://purl.bioontology.org/ontology/SNOMEDCT/33339001 Psoriasis with arthropathy peo2:Puerperal_endometritis Puerperal endometritis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/22399000 Puerperal endometritis peo2:Pulasatility_index PI Pulasatility index peo2:Pulmonary_embolism PE - Pulmonary embolism Pulmonary embolism (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/59282003 Pulmonary embolism peo2:Purpose http://semanticscience.org/resource/SIO_000359 Purpose peo2:RAS_targeting_drugs Renin-angiotensin-aldosterone system-targeting drugs RAS targeting drugs peo2:RYGB Roux-en-Y gastric-bypass RYGB peo2:Realtive_risk AD306 Relative risk peo2:Recurrent_miscarriage Habitual aborter Habitual abortion Recurrent aborter Recurrent abortion Recurrent miscarriage (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/102878001 Recurrent miscarriage peo2:Red_blood_cell_count RBC - Red blood cell count RBC count Red blood cell count (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/14089001 Red blood cell count peo2:Red_blood_cell_disorder Red blood cell disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/38292009 Red blood cell disorder peo2:Regularly_used Regularly used peo2:Regulation_of_transcription regulation of cellular transcription, DNA-dependent http://purl.org/obo/owl/GO#GO_0006355 AD614 Regulation of transcription peo2:Remote_Hypertension Remote Hypertension peo2:Renal_failure http://purl.bioontology.org/ontology/OMIM/MTHU000623 Renal failure peo2:Renin_inhibitor Renin inhibitor (substance) http://purl.bioontology.org/ontology/SNOMEDCT/426228001 Renin inhibitor peo2:Reperfusion_Injury Damage, Reperfusion Damages, Reperfusion Injuries, Ischemia-Reperfusion Injuries, Reperfusion Injury, Ischemia Reperfusion Injury, Ischemia-Reperfusion Injury, Reperfusion Ischemia Reperfusion Injury Ischemia-Reperfusion Injuries Ischemia-Reperfusion Injury Reperfusion Damage Reperfusion Damages Reperfusion Injuries http://purl.bioontology.org/ontology/MESH/D015427 Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY. Reperfusion Injury peo2:Reproductive_Techniques_Assisted ART Assisted Reproductive Techniques http://purl.bioontology.org/ontology/MESH/D027724 Reproductive Techniques, Assisted peo2:Resveratrol Resveratrol (substance) http://purl.bioontology.org/ontology/SNOMEDCT/96383001 Resveratrol peo2:Retention_of_placenta Retention of placenta peo2:Rheumatoid_arthritis Atrophic arthritis Chronic rheumatic arthritis Proliferative arthritis RA - Rheumatoid arthritis RhA - Rheumatoid arthritis Rheumatic gout Rheumatoid arthritis (disorder) Rheumatoid disease http://purl.bioontology.org/ontology/SNOMEDCT/69896004 Rheumatoid arthritis peo2:Right-sided_unilateral_notching Unilateral right notch Right-sided unilateral notching peo2:Rupture_of_gravid_uterus Obstetrical rupture of uterus Rupture of gravid uterus (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/15504009 Rupture of gravid uterus peo2:Ruptured_membranes ROM - Ruptured membranes Rupture of fetal membranes Rupture of foetal membranes Rupture of membranes Ruptured membranes (disorder) Spontaneous rupture of fetal membranes Spontaneous rupture of foetal membranes Waters broken http://purl.bioontology.org/ontology/SNOMEDCT/41957003 Ruptured membranes peo2:Schizophrenia Schizophrenia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/58214004 Schizophrenia peo2:School_attendance School attendance (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/228134009 School attendance peo2:Schooling Schooling (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/266981003 Schooling peo2:Seasons Season Seasonal Variation Seasonal Variations Variation, Seasonal Variations, Seasonal http://purl.bioontology.org/ontology/MESH/D012621 Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Seasons peo2:Second_trimester 2nd trimester Second trimester (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255247007 Second trimester peo2:Segmentation Segmentation (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/257928003 Segmentation peo2:Seizure_disorder Seizure disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/128613002 Seizure disorder peo2:Selenium Se - Selenium Selenium (substance) http://purl.bioontology.org/ontology/SNOMEDCT/22038003 Selenium peo2:Sepsis Sepsis (disorder) Systemic infection http://purl.bioontology.org/ontology/SNOMEDCT/91302008 Sepsis peo2:Serum_lipid_levels_-_finding Finding of serum lipid levels Finding of serum lipid levels (finding) Serum lipid levels http://purl.bioontology.org/ontology/SNOMEDCT/365798004 Serum lipid levels - finding peo2:Serum_testosterone_measurement Serum testosterone level Serum testosterone measurement (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/270973006 Serum testosterone measurement peo2:Serum_total_HCG_measurement Measurement of serum total human chorionic gonadotrophin Measurement of serum total human chorionic gonadotropin Measurement of serum total human chorionic gonadotropin (procedure) Serum total HCG level Serum total human chorionic gonadotrophin measurement Serum total human chorionic gonadotropin measurement http://purl.bioontology.org/ontology/SNOMEDCT/167037004 Serum total HCG measurement peo2:Sexually_transmitted_infectious_disease Disease with a predominantly sexual mode of transmission STD - Sexually transmitted disease Sexually transmitted disease VD - Venereal disease http://purl.bioontology.org/ontology/SNOMEDCT/8098009 Sexually transmitted infectious disease peo2:Single_person Single Single person (finding) http://purl.bioontology.org/ontology/SNOMEDCT/125681006 Not currently married Single person peo2:Single_pregnancy Single pregnancy (finding) http://purl.bioontology.org/ontology/SNOMEDCT/237244005 Single pregnancy peo2:Singleton_delivery Singleton delivery peo2:Sjogrens_syndrome Sicca syndrome Sjogren's syndrome Sjogrens syndrome Sjögren syndrome Sjögren's disease Sjögren's syndrome (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/83901003 Sjögren's syndrome peo2:Small_for_gestational_age_fetus http://purl.bioontology.org/ontology/SNOMEDCT/267258002 Fetus small-for-dates Infant underweight for gestational age Light for dates Light for gestational age Light for gestational dates SFD - Fetus small-for-dates SGA - Small for gestational age fetus Small for gestational age Small for gestational age fetus (disorder) Subnormal birth weight Small for gestational age fetus peo2:Small_molecules http://purl.bioontology.org/ontology/LNC/LP31415-0 Small molecules peo2:Smoking_during_pregnancy Smoking during pregnancy peo2:Smooth_muscle_cells_of_vessel Smooth muscle cells of vessel peo2:Snuff_user Snuff taker Snuff user (finding) http://purl.bioontology.org/ontology/SNOMEDCT/228494002 Snuff user peo2:Social_context Social context (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/48176007 Social context peo2:Social_support_status Social support status (finding) http://purl.bioontology.org/ontology/SNOMEDCT/445051000124100 Social support status peo2:Sodium_transport sodium transport http://purl.org/obo/owl/GO#GO_0006814 AD617 Sodium transport peo2:Spermatogenesis Spermatocytogenesis Spermatogenesis, function Spermatogenesis, function (observable entity) http://purl.bioontology.org/ontology/SNOMEDCT/20412003 Spermatogenesis peo2:Spiral_arteries Spiral arteries peo2:Spiral_artery_remodeling Spiral artery remodeling peo2:Splicing_variants Splicing variant AD615 regulation via splicing variants peo2:Spontaneous_labor Spontaneous labor peo2:Sporadic_miscarriage Sporadic miscarriage peo2:Stage_2_hypertension Stage 2 hypertension peo2:Stage_2_systolic_hypertension Stage 2 systolic hypertension peo2:Standardized_incidence_ratio AD315 Standardized incidence ratio peo2:Status_epilepticus Status epilepticus (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/230456007 Status epilepticus peo2:Stillbirth SB - Stillbirth Stillbirth (finding) http://purl.bioontology.org/ontology/SNOMEDCT/237364002 Stillbirth peo2:Stopped_smoking Stopped smoking (finding) http://purl.bioontology.org/ontology/SNOMEDCT/160617001 Stopped smoking peo2:Students_t_test Student's t-tests from manual annotation of text corpus Student's t-test peo2:Subarachnoid_hemorrhage SAH - Subarachnoid haemorrhage SAH - Subarachnoid hemorrhage Subarachnoid haemorrhage Subarachnoid intracranial haemorrhage Subarachnoid intracranial hemorrhage Subarachnoid intracranial hemorrhage (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/21454007 Subarachnoid hemorrhage peo2:Subdural peo2:Substances_used Substances used (attribute) http://purl.bioontology.org/ontology/SNOMEDCT/246480001 Substances used peo2:Sumoylation SUMO-protein conjugation protein sumolation small ubiquitin-related protein 1 conjugation sumoylation http://purl.org/obo/owl/GO#GO_0016925 AD598 Sumoylation peo2:Supplements Supplements peo2:Swelling_of_endothelial_cells http://purl.bioontology.org/ontology/OMIM/MTHU040828 Swelling of endothelial cells peo2:Systemic_lupus_erythematosus-related_syndrome SLE - Systemic lupus erythematosus-related syndrome Systemic lupus erythematosus-related syndrome (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/397856003 Systemic lupus erythematosus-related syndrome peo2:Systolic_arterial_pressure Systolic arterial pressure (observable entity) Systolic blood pressure http://purl.bioontology.org/ontology/SNOMEDCT/72313002 Systolic arterial pressure peo2:THROMBOPHILIA_DUE_TO_THROMBIN_DEFECT THPH1 THROMBOPHILIA DUE TO FACTOR 2 DEFECT THROMBOSIS, PROTECTION AGAINST VENOUS THROMBOEMBOLISM VENOUS THROMBOSIS http://purl.bioontology.org/ontology/OMIM/188050 THROMBOPHILIA DUE TO THROMBIN DEFECT peo2:T_lymphocyte T cell T lymphocyte (cell) T-cell http://purl.bioontology.org/ontology/SNOMEDCT/57184004 T lymphocyte peo2:Termination_of_pregnancy Abortion Induced abortion Induced termination of pregnancy Induced termination of pregnancy (disorder) Termination of pregnancy (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/386639001 Termination of pregnancy peo2:Th1_Cells Cell, Th1 Cells, Th1 Th1 Cell http://purl.bioontology.org/ontology/MESH/D018417 Subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions. Th1 Cells peo2:Th2_Cells Cell, Th2 Cells, Th2 Th2 Cell http://purl.bioontology.org/ontology/MESH/D018418 Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses. Th2 Cells peo2:Therapeutics Therapeutic Therapies Therapy Treatment Treatments http://purl.bioontology.org/ontology/MESH/D013812 Therapeutics peo2:Third_trimester 3rd trimester Third trimester (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/255248002 Third trimester peo2:Thrombocytopenic_disorder Thrombocytopenia Thrombocytopenic disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/302215000 Thrombocytopenic disorder peo2:Thromboembolic_disorder Thromboembolic disease Thromboembolic disorder (disorder) Thromboembolism http://purl.bioontology.org/ontology/SNOMEDCT/371039008 Thromboembolic disorder peo2:Thrombophilia Thrombophilia (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/234467004 Thrombophilia peo2:Thromboprophylaxis Thromboprophylaxis peo2:Thrombosis Thrombosis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/439127006 Thrombosis peo2:Thyroid_disease http://purl.bioontology.org/ontology/OMIM/MTHU018343 Thyroid disease peo2:Thyroid_supplements Thyroid supplements peo2:Tobacco_use_and_exposure_-_finding Finding of tobacco use and exposure Finding of tobacco use and exposure (finding) http://purl.bioontology.org/ontology/SNOMEDCT/365980008 Tobacco use and exposure - finding peo2:Total_cholesterol Total cholesterol (substance) http://purl.bioontology.org/ontology/SNOMEDCT/301860006 Total cholesterol peo2:Toxic_causes Toxic causes AD457 Toxic cause peo2:Transaminases Aminotransferases http://purl.bioontology.org/ontology/MESH/D000637 A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1. Transaminases peo2:Transfection_cells Transfection cells models AD645 Transfection cells model peo2:Transgeneic_cells Transgenic models AD646 Transgenic model peo2:Transient_cerebral_ischemia Intermittent cerebral ischaemia Intermittent cerebral ischemia TIA TIA - Transient ischaemic attack Temporary cerebral vascular dysfunction Transient cerebral ischaemia Transient ischaemic attack Transient ischemic attack Transient ischemic attack (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/266257000 Transient cerebral ischemia peo2:Trimesters Trimesters (qualifier value) http://purl.bioontology.org/ontology/SNOMEDCT/272107002 Trimesters peo2:Trophoblast_invasion Trophoblast invasion peo2:Trophoblasts Cytotrophoblast Cytotrophoblasts Syncytiotrophoblast Syncytiotrophoblasts Trophoblast http://purl.bioontology.org/ontology/MESH/D014327 Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA). Trophoblasts with multinuclear cytoplasm and undefined cellular structures. Syncytiotrophoblasts secrete proteolytic enzymes that erode the ENDOMETRIUM for EMBRYO IMPLANTATION. They also produce steroid, peptide, and protein hormones (PLACENTAL HORMONES). Trophoblasts with single nucleus and defined cellular structures. As the PLACENTA develops, pockets of cytotrophoblasts serve as stem cells for syncytiotrophoblasts. Trophoblasts peo2:Tuberculosis TB - Tuberculosis Tuberculosis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/56717001 Tuberculosis peo2:Twin_birth Twin birth (finding) http://purl.bioontology.org/ontology/SNOMEDCT/28030000 Twin birth peo2:Twin_pregnancy Twin pregnancy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/65147003 Twin pregnancy peo2:Type_1_diabetes_mellitus Diabetes mellitus type 1 Diabetes mellitus type 1 (disorder) Diabetes mellitus type I Type I diabetes mellitus http://purl.bioontology.org/ontology/SNOMEDCT/46635009 Type 1 diabetes mellitus peo2:Type_2_diabetes_mellitus Diabetes mellitus type 2 Diabetes mellitus type 2 (disorder) Diabetes mellitus type II Type II diabetes mellitus http://purl.bioontology.org/ontology/SNOMEDCT/44054006 Type 2 diabetes mellitus peo2:Ubiquitination AD629 Ubiquitination peo2:Ultrasonography Diagnostic sonar Diagnostic ultrasonography Diagnostic ultrasonography (procedure) US - Ultrasound USS - Ultrasound scan Ultrasonogram Ultrasound Ultrasound procedure Ultrasound scan http://purl.bioontology.org/ontology/SNOMEDCT/16310003 Ultrasonography peo2:Umbilical_cord_finding Umbilical cord finding (finding) Umbilical cord observations http://purl.bioontology.org/ontology/SNOMEDCT/289299005 Umbilical cord finding peo2:Unilateral_notching Bilateral notching Unilateral notching peo2:Unsafe_living_conditions Unsafe living conditions peo2:Upper_class_economic_status Upper class economic status (social concept) high regional economic status high socio economic status high socioeconomic status http://purl.bioontology.org/ontology/SNOMEDCT/85483007 Upper class economic status peo2:Upper_middle_class_economic_status Upper middle class economic status (social concept) http://purl.bioontology.org/ontology/SNOMEDCT/64816001 Upper middle class economic status peo2:Upregulation AD616 Upregulation peo2:Urinary_tract_infection_in_pregnancy UTI - urinary tract infection in pregnancy Urinary tract infection complicating pregnancy Urinary tract infection in pregnancy (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/307534009 Urinary tract infection in pregnancy peo2:Urinary_tract_infections http://purl.bioontology.org/ontology/OMIM/MTHU007522 Urinary tract infections peo2:UtA-RI uterine artery resistance index UtA-RI peo2:UtAD_velocimetry uterine artery Doppler velocimetry UtAD velocimetry peo2:Uterine_Artery Arteries, Uterine Artery, Uterine Uterine Arteries http://purl.bioontology.org/ontology/MESH/D055988 A branch arising from the internal iliac artery in females, that supplies blood to the uterus. Uterine Artery peo2:Uterine_blood_flow Uterine blood flow peo2:Uteroplacental_blood_flow Uteroplacental blood flow peo2:Uterotonic Uterotonic peo2:VEGF_system VEGF system peo2:Vaginal_delivery Vaginal delivery (finding) http://purl.bioontology.org/ontology/SNOMEDCT/289259007 Vaginal delivery peo2:Vascular_constriction Vascular constriction, function Vascular constriction, function (observable entity) Vasoconstriction http://purl.bioontology.org/ontology/SNOMEDCT/32318003 Vascular constriction peo2:Vascular_disorders http://purl.bioontology.org/ontology/MEDDRA/10047065 Vascular disorders peo2:Vascular_luminal_abnormality Vascular luminal abnormality peo2:Vascular_system_finding Vascular system finding peo2:Vascular_tone Vascular tone peo2:Vascular_wall_hypertrophy http://purl.bioontology.org/ontology/MEDDRA/10072810 Vascular wall hypertrophy peo2:Vasculitis Angiitis Vasculitis (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/31996006 Vasculitis peo2:Vasodepressor_activity Vasodepressor activity peo2:Vasodilatory_effects Vasodilatory effects peo2:Vasogenic_cerebral_edema Vasogenic cerebral edema (disorder) Vasogenic cerebral oedema http://purl.bioontology.org/ontology/SNOMEDCT/230759001 Vasogenic cerebral edema peo2:Velocity_time_integral_ratio VTI ratio Velocity time integral ratio peo2:Vertebral_artery_dissection Vertebral artery dissection (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/230730001 Vertebral artery dissection peo2:Vertex_presentation Cephalic presentation Vertex presentation (finding) http://purl.bioontology.org/ontology/SNOMEDCT/70028003 Vertex presentation peo2:Vesicular_transport vesicle transport vesicular transport http://purl.org/obo/owl/GO#GO_0016192 AD508 Vesicular transport peo2:Villous_Hemosiderosis Villous Hemosiderosis peo2:Vitamin_E http://purl.obolibrary.org/obo/CHEBI_33234 Vitamin E peo2:Vomiting Emesis Vomiting (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/422400008 Vomiting peo2:White-collar_worker http://en.wikipedia.org/wiki/White-collar_worker White-collar worker peo2:White_-_ethnic_group White White - ethnic group (ethnic group) http://purl.bioontology.org/ontology/SNOMEDCT/185984009 White - ethnic group peo2:Whole_blood_folate_level_-_finding Finding of whole blood folate level Finding of whole blood folate level (finding) Whole blood folate level http://purl.bioontology.org/ontology/SNOMEDCT/365609009 Whole blood folate level - finding peo2:Xiusanzhen from manual annotation of text corpus electroacupuncture Xiusanzhen peo2:Zero_flow_pressure ZFP Zero flow pressure peo2:adipose_control adipose control peo2:adrenaline (+-)-adrenaline (+-)-epinephrine 2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol C9H13NO3 CNCC(O)c1ccc(O)c(O)c1 InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 InChIKey=UCTWMZQNUQWSLP-UHFFFAOYSA-N dl-adrenaline epinephrine racemic racepinefrina racepinefrine racepinefrinum http://purl.obolibrary.org/obo/CHEBI_33568 A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen. adrenaline peo2:alcohol from manual annotation of text corpus alcohol peo2:alcohol_molecule Alcohol HOR O[*] alcohols an alcohol http://purl.obolibrary.org/obo/CHEBI_30879 A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. alcohol peo2:aldosterone (+)-aldosterone (11alpha,14beta,17alpha)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al ALDOSTERONE Aldosterone C21H28O5 InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 InChIKey=PQSUYGKTWSAVDQ-ZVIOFETBSA-N [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C aldosterone http://purl.obolibrary.org/obo/CHEBI_27584 A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. aldosterone peo2:angiogenesis http://purl.obolibrary.org/obo/GO_0001525 blood vessel formation from pre-existing blood vessels angiogenesis peo2:anti-HVEM HVEM antibody anti-HVEM peo2:anti-LTBR LTBR antibody anti-LTBR peo2:anti-PLAP anti-placental alkaline phosphatase anti-PLAP peo2:anti-TNFRSF14 TNFRSF14 antibody anti-TNFRSF14 peo2:anticoagulation anticoagulation peo2:antiinflammatory_drugs Drugs with analgesic and antipyretic (fever-reducing) effects and which have, in higher doses, anti-inflammatory effects. anti-inflammatory drugs anti-inflammatory drug peo2:antioxidant http://en.wikipedia.org/wiki/Antioxidant antioxidants from NP chunking Molecule capable of inhibiting the oxidation of other molecules antioxidant peo2:aortic_smooth_muscle_cell http://purl.obolibrary.org/obo/CL_0002539 A smooth muscle cell of the aorta aortic smooth muscle cell peo2:apocynin 4'-hydroxy-3'-methoxyacetophenone apocynin peo2:apoptotic_signalling from manual annotation of text corpus apoptotic signalling peo2:arachidonic_acid (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoic acid (5Z,8Z,11Z,14Z)-Icosatetraenoic acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid AA ARA ARACHIDONIC ACID Arachidonate Arachidonic acid Arachidonsaeure C20H32O2 CCCCCC=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- InChIKey=YZXBAPSDXZZRGB-DOFZRALJSA-N all-cis-5,8,11,14-eicosatetraenoic acid cis-5,8,11,14-Eicosatetraenoic acid cis-Delta(5,8,11,14)-eicosatetraenoic acid http://purl.obolibrary.org/obo/CHEBI_15843 A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14. arachidonic acid peo2:baseline_state baseline baseline states from NP chunking In pharmacology and matters of biochemistry, baseline describes a person's state of mind or being with the absence of drugs. For example, after an LSD trip, baseline would be the point where the user is completely under control and no longer experiences any effects. source: http://en.wikipedia.org/wiki/Baseline_%28pharmacology%29 baseline state peo2:beta_Carotene BellaCarotin Betacarotene Hermal Brand Betacarotene Roche Brand Betacarotene Solgar Brand Carotaben Marlyn Brand of Betacarotene Max Caro Max-Caro MaxCaro Solatene beta Carotene peo2:bilirubin 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione Bilirubin C33H36N4O6 CC1=C(C=C)C(NC1=O)=C\c1[nH]c(Cc2[nH]c(\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC(O)=O)c(CCC(O)=O)c1C InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14- InChIKey=BPYKTIZUTYGOLE-IFADSCNNSA-N bilirubin bilirubin IXalpha http://purl.obolibrary.org/obo/CHEBI_16990 A member of the class of biladienes that is a linear tetrapyrrole, product of heme degradation. It is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. bilirubin peo2:biliverdin 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbilin-1(19)(21H,24H)-dione BILIVERDINE IX ALPHA Biliverdin Biliverdin IXalpha Biliverdine C33H34N4O6 CC1=C(CCC(O)=O)C(/N=C1/C=C1NC(=O)C(C=C)=C/1C)=C\c1[nH]c(\C=C2NC(=O)C(C)=C/2C=C)c(C)c1CCC(O)=O InChI=1S/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15- InChIKey=QBUVFDKTZJNUPP-BBROENKCSA-N biliverdin http://purl.obolibrary.org/obo/CHEBI_17033 A linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase. biliverdin peo2:blinded_study blinded studies blinded study peo2:bmi from manual annotation of text corpus body mass index BMI peo2:body_weigtht_before_14wk Body weight before 14 wk peo2:calcium_signalling from manual annotation of text corpus calcium signalling peo2:carbon_monoxide C#O CARBON MONOXIDE CO Carbon monoxide InChI=1S/CO/c1-2 InChIKey=UGFAIRIUMAVXCW-UHFFFAOYSA-N [C-]#[O+] [CO] carbon monooxide carbon monoxide carbon(II) oxide http://purl.obolibrary.org/obo/CHEBI_17245 A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. carbon monoxide peo2:case_report case reports from NP chunking case report peo2:cell_cycle_process cell-cycle processes from manual annotation of text corpus cell-cycle process peo2:cell_growth cell expansion; non-developmental growth of a unicellular organism; metabolic process resulting in cell growth; metabolism resulting in cell growth; non-developmental cell growth cellular growth; growth of cell http://purl.obolibrary.org/obo/GO_0016049 cell growth peo2:cell_signalling from manual annotation of text corpus cell signalling peo2:chi_square Chi-Square Chi-Square tests from manual annotation of text corpus Chi-Square test peo2:cholesterol (3beta,14beta,17alpha)-cholest-5-en-3-ol C27H46O CHOLESTEROL Cholest-5-en-3beta-ol Cholesterin Cholesterol InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 InChIKey=HVYWMOMLDIMFJA-DPAQBDIFSA-N [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C cholest-5-en-3beta-ol cholesterol http://purl.obolibrary.org/obo/CHEBI_16113 A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group. cholesterol peo2:clinical_functional_phenotype_context clinical functional phenotype context peo2:clinical_main_complaint_context clinical main complaint context peo2:clinical_observation_context clinical observation context peo2:clinical_outcome_context clinical outcome context peo2:clinical_phenotypic_context clinical phenotypic context peo2:comparative_study comparative studies from NP chunking comparative study peo2:control_subject control subjects from NP chunking shouldn't this be a role? control subject peo2:corticosteroid corticoides corticosteroides corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858 A natural or synthetic analogue of the hormones secreted by the adrenal gland. corticosteroid peo2:delivery_mode http://purl.bioontology.org/ontology/HL7/C1555567 Indicates the type of service offered, method of delivery. For example: post office box, rural route, general delivery, etc. delivery mode peo2:disease_onset onset onset of AD from NP chunking disease onset peo2:diuretic diuretics http://purl.obolibrary.org/obo/CHEBI_35498 An agent that promotes the excretion of urine through its effects on kidney function. diuretic peo2:dose_ranging_study dose ranging studies dose ranging study peo2:double_blinded_study blinded double blinded studies double-blind double blinded study peo2:double_masked_study double masked studies double masked study peo2:drug drug peo2:dyslipidemia from manual annotation of text corpus dyslipidemia peo2:early_onset_context early onset context peo2:eicosanoids eicosanoids peo2:eosin_YS_dye 2',4',5',7'-Tetrabromo-3',6'-dihydroxyspiro(isobenzofuran-1(3H),9-'-(9H)xanthen)-3-one, disodium salt Acid red 87 C20H6Br4Na2O5 Eosin Y Eosine G Eosine Yellowish InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2 InChIKey=SEACYXSIPDVVMV-UHFFFAOYSA-L [Na+].[Na+].[O-]C(=O)c1ccccc1-c1c2cc(Br)c([O-])c(Br)c2oc2c(Br)c(=O)c(Br)cc12 disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate http://purl.obolibrary.org/obo/CHEBI_52053 An organobromine compound that has formula C20H6Br4Na2O5. eosin YS dye peo2:estrogen Estrogene Oestrogen Oestrogene estrogene estrogenes estrogenes Hormon estrogeno estrogenos estrogens oestrogen oestrogene oestrogenes oestrogens http://purl.obolibrary.org/obo/CHEBI_50114 A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. estrogen peo2:folic_acid C19H19N7O6 FOLIC ACID Folate Folic acid Folsaeure InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 InChIKey=OVBPIULPVIDEAO-LBPRGKRZSA-N N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid N-pteroyl-L-glutamic acid Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@ PGA PteGlu Pteroylglutamic acid pteroyl-L-glutamic acid pteroyl-L-monoglutamic acid vitamin Bc vitamin M http://purl.obolibrary.org/obo/CHEBI_27470 An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation. folic acid peo2:glucose C6H12O6 Glc Glucose Glukose gluco-hexose glucose http://purl.obolibrary.org/obo/CHEBI_17234 An aldohexose used as a source of energy and metabolic intermediate. glucose peo2:hCG-PlGF_ratio hCG-PlGF ratio peo2:haematoxylin 7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol 7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol C16H14O6 Haematoxylin InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2 InChIKey=WZUVPPKBWHMQCE-UHFFFAOYSA-N Oc1cc2CC3(O)COc4c(O)c(O)ccc4C3c2cc1O hematoxilina hematoxylin hematoxyline http://purl.obolibrary.org/obo/CHEBI_51686 An organic heterotetracyclic compound that has formula C16H14O6. haematoxylin peo2:hemoglobin haemoglobin hemoglobin vertebrate haemoglobin http://purl.obolibrary.org/obo/CHEBI_35143 hemoglobin peo2:heparin (C26H40N2O36S5)n Bemiparin Certoparin Cy 222 Enoxaparin Fluxum Heparin Heparinic acid Parnaparin Reviparin Sandoparin heparin heparina heparine heparinum http://purl.obolibrary.org/obo/CHEBI_28304 A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1->4)-D-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule. heparin peo2:high-density_lipoprotein_cholesterol HDL cholesterol HDL-C alpha-lipoprotein cholesterol http://purl.obolibrary.org/obo/CHEBI_47775 Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL). high-density lipoprotein cholesterol peo2:hormone endocrine hormones http://purl.obolibrary.org/obo/CHEBI_24621 Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. hormone peo2:hypertension from NP chunking hypertension peo2:immunotherapy http://en.wikipedia.org/wiki/Immunotherapy AD-directed immunotherapy immunotherapies from manual annotation of text corpus Treatment of disease by inducing, enhancing, or suppressing an immune response immunotherapy peo2:inflammation acute inflammatory response chronic inflammation inflammations inflammatory inflammatory cascade inflammatory cascades inflammatory response inflammatory responses peripheral inflammation from NP chunking from manual annotation of text corpus inflammation peo2:insulin_signalling insulin resistance from manual annotation of text corpus insulin signalling peo2:intervention_study intervention studies intervention study peo2:ion Ion Ionen ion iones ions http://purl.obolibrary.org/obo/CHEBI_24870 A molecular entity having a net electric charge. ion peo2:ischemic_lesion ischemic lesions from manual annotation of text corpus ischemic lesion peo2:isoflurane 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether 2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane Aerrane C3H2ClF5O Ethane FC(F)OC(Cl)C(F)(F)F Forane Forene InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H InChIKey=PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane isoflurane isoflurano isofluranum http://purl.obolibrary.org/obo/CHEBI_6015 An organofluorine compound that has formula C3H2ClF5O. isoflurane peo2:lamina-associated_polypeptide_2 LAP2 (protein) LAP2alpha LAP2beta http://purl.bioontology.org/ontology/MESH/C093413 lamina-associated polypeptide 2 peo2:late_onset_context late onset context peo2:lateral_E_wave_velocity lateral E' wave velocity lateral E' wave velocity peo2:lipid Lipid lipids lipid peo2:lipid_peroxidation from manual annotation of text corpus lipid peroxidation peo2:low-density_lipoprotein_cholesterol LDL cholesterol LDL-C beta-lipoprotein cholesterol http://purl.obolibrary.org/obo/CHEBI_47774 Cholesterol esters and free cholesterol which are contained in or bound to low-density lipoproteins (LDL). low-density lipoprotein cholesterol peo2:marriageable_age adolescent adolescents adult adults marriageable age peo2:metabolic_change metabolic changes from manual annotation of text corpus metabolic change peo2:metal_chelation chelate metals from manual annotation of text corpus metal chelation peo2:metformin 1,1-Dimethylbiguanide C4H11N5 CN(C)C(=N)NC(N)=N InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8) InChIKey=XZWYZXLIPXDOLR-UHFFFAOYSA-N Metformin N,N-dimethylimidodicarbonimidic diamide http://purl.obolibrary.org/obo/CHEBI_6801 A member of the class of guanidines that is the 1,1-dimethyl derivative of biguanide. metformin peo2:mitochondrial_change mitochondrial changes from manual annotation of text corpus mitochondrial change peo2:mitochondrial_dysfunctioning from NP chunking mitochondrial dysfunctioning peo2:mixed Mixed racial group (racial group) http://purl.bioontology.org/ontology/SNOMEDCT/414752008 Mixed racial group peo2:mo_6_24_postportum 6-24 month postportum peo2:mononuclear_cell peripheral blood mononuclear cell http://purl.obolibrary.org/obo/CL_0000842 mononuclear cell peo2:negative_regulation_of_apoptotic_process down-regulation of apoptosis; downregulation of apoptosis; anti-apoptosis; down regulation of apoptosis inhibition of apoptosis; negative regulation of apoptosis pro-survival; apoptosis inhibitor activity http://purl.obolibrary.org/obo/GO_0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. negative regulation of apoptotic process peo2:nitric_oxide (.)NO (NO)(.) EDRF InChI=1S/NO/c1-2 InChIKey=MWUXSHHQAYIFBG-UHFFFAOYSA-N NITRIC OXIDE NO NO(.) Nitric oxide Nitrogen monoxide Stickstoff(II)-oxid Stickstoffmonoxid [NO] [N]=O endothelium-derived relaxing factor mononitrogen monoxide monoxido de nitrogeno monoxyde d'azote nitric oxide nitrogen monooxide nitrogen monoxide nitrosyl oxido de nitrogeno(II) oxido nitrico oxidonitrogen(.) oxoazanyl oxyde azotique oxyde nitrique http://purl.obolibrary.org/obo/CHEBI_16480 A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom. nitric oxide peo2:noradrenaline 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol C8H11NO3 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 InChIKey=SFLSHLFXELFNJZ-UHFFFAOYSA-N NCC(O)c1ccc(O)c(O)c1 noradrenalina norepinephrine http://purl.obolibrary.org/obo/CHEBI_33569 A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted. noradrenaline peo2:older_than_marriageable_age high maternal age increased maternal age older than 35 years old older than marriageable age peo2:open_label_study open label study peo2:outcome_assessor outcome assessors shouldn't this be a role? outcome assessor peo2:oxygen_atom 8O InChI=1S/O InChIKey=QVGXLLKOCUKJST-UHFFFAOYSA-N O Sauerstoff [O] oxigeno oxygen oxygene http://purl.obolibrary.org/obo/CHEBI_25805 A chalcogen that has formula O. oxygen atom peo2:oxytocin (1-Hemicystine)oxytocin 1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide 3-Isoleucine-8-leucine vasopressin A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour. C43H66N12O12S2 Endopituitrina InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 InChIKey=XNOPRXBHLZRZKH-DSZYJQQASA-N L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide OT OXT Ocytocin Orasthin Oxytocin Pitocin Piton S Syntocinon [H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)[C@ oxitocina oxytocin oxytocine oxytocinum http://purl.obolibrary.org/obo/CHEBI_7872 oxytocin peo2:perfluorodecanoic_acid 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluorodecanoic acid C10HF19O2 InChI=1S/C10HF19O2/c11-2(12,1(30)31)3(13,14)4(15,16)5(17,18)6(19,20)7(21,22)8(23,24)9(25,26)10(27,28)29/h(H,30,31) InChIKey=PCIUEQPBYFRTEM-UHFFFAOYSA-N Ndfda OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F PFDA nonadecafluoro-n-decanoic acid nonadecafluorodecanoic acid perfluoro-n-decanoic acid perfluorodecanoic acid A fluoroalkanoic acid that is perfluorinated decanoic acid. perfluorodecanoic acid peo2:perfluorononanoic_acid PFNA http://purl.bioontology.org/ontology/MESH/C584865 perfluorononanoic acid peo2:perfluorooctane_sulfonic_acid 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- PFOS compound PFOSA Perfluorooctanesulfonate heptadecafluoro-1-octane sulfonic acid heptadecafluorooctane sulfonic acid http://purl.bioontology.org/ontology/MESH/C076994 perfluorooctane sulfonate perfluorooctane sulphonic acid perfluorooctanesulfonic acid perfluorooctanyl sulfonate perfluorooctane sulfonic acid peo2:perfluorooctanoic_acid APFO PFOA cpd ammonium perfluorooctanoate pentadecafluorooctanoic acid perfluorinated octanoic acid perfluorooctanoate perfluorooctanoic acid, anhydride perfluorooctanoic acid, cesium salt perfluorooctanoic acid, chromium (3+) salt perfluorooctanoic acid, cobalt (2+) salt perfluorooctanoic acid, lithium salt perfluorooctanoic acid, monoammonium salt perfluorooctanoic acid, monopotassium salt perfluorooctanoic acid, monosilver (1+) salt perfluorooctanoic acid, monosodium salt perfluorooctanoyl chloride sodium perfluorooctanoate http://purl.bioontology.org/ontology/MESH/C023036 perfluorooctanoic acid peo2:perfluoroundecanoic_acid PFUA compound http://purl.bioontology.org/ontology/MESH/C586085 perfluoroundecanoic acid peo2:performing_physical_activity high physical activity physical activities physical activity performing physical activity peo2:peroxynitrite peroxynitrite peo2:phase_0 phase 0 peo2:phase_2A phase 2A peo2:phase_2B phase 2B peo2:phosphatidylinositol_signalling from manual annotation of text corpus phospatidylinositol signalling peo2:plumbum Pb from manual annotation of text corpus plumbum peo2:potassium InChI=1S/K/q+1 InChIKey=NPYPAHLBTDXSSS-UHFFFAOYSA-N K K(+) K+ POTASSIUM ION [K+] potassium potassium cation potassium(1+) potassium(1+) ion potassium(I) cation http://purl.obolibrary.org/obo/CHEBI_29103 A monoatomic monocation obtained from potassium. potassium(1+) peo2:prepregnancy_body_weight Prepregnancy body weight peo2:primary_purpose_design primary purpose designs what is this? primary purpose design peo2:procedures_using_biomarkers biological marker biomarker A biomarker is a substance used as an indicator of a biological state thing related to procedure using biomarkers peo2:processes_all_cells processes all cells peo2:progesterone (S)-4-Pregnene-3,20-dione (S)-Pregn-4-en-3,20-dione (S)-Progesterone 17alpha-progesterone 4-Pregnene-3,20-dione Agolutin Akrolutin C21H30O2 Crinone Delta(4)-pregnene-3,20-dione Gelbkoerperhormon InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1 InChIKey=RJKFOVLPORLFTN-LEKSSAKUSA-N PROGESTERONE Progesteron Progesterone [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@ corpus luteum hormone luteohormone pregn-4-ene-3,20-dione progesterone http://purl.obolibrary.org/obo/CHEBI_17026 A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species. progesterone peo2:protein_synthesis CPS cerebral protein synthesis rCPS protein synthesis peo2:randomized_study from manual annotation of text corpus randomized studies randomized study peo2:regulation_of_cell_adhesion cell adhesion receptor regulator activity http://purl.obolibrary.org/obo/GO_0030155 Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. regulation of cell adhesion peo2:regulation_of_immune_system_process http://purl.obolibrary.org/obo/GO_0002682 Any process that modulates the frequency, rate, or extent of an immune system process. regulation of immune system process peo2:sFlt1-PlGF_ratio sFlt1-PlGF ratio peo2:single_blind_study blinded single blind studies single blind study peo2:single_masked_study single masked studies single masked study peo2:sleep_disorder Sleep disorder (disorder) http://purl.bioontology.org/ontology/SNOMEDCT/39898005 sleep disorder peo2:somatostatin Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys] C76H104N18O19S2 C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 InChIKey=NHXLMOGPVYXJNR-ATOGVRKGSA-N L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide Somatostatin-1 Somatostatin-14 Synthetic growth hormone release-inhibiting hormone somatostatin somatostatina somatostatine somatostatinum http://purl.obolibrary.org/obo/CHEBI_64628 A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14. somatostatin peo2:steroid_biosynthetic_process steroid anabolism steroid biosynthesis steroid formation steroid synthesis steroidogenesis http://purl.obolibrary.org/obo/GO_0006694 The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. steroid biosynthetic process peo2:steroid_hormone Steroidhormon Steroidhormone hormona esteroide hormonas esteroideas hormone steroide hormones steroides steroid hormones http://purl.obolibrary.org/obo/CHEBI_26764 Any steroid that acts as hormone. steroid hormone peo2:stroke strokes from NP chunking stroke peo2:study_caregiver study caregivers shouldn't this be a role? study caregiver peo2:study_investigator study investigators shouldn't this be a role? study investigator peo2:study_nurse study nurse peo2:study_subject study subjects study subject peo2:survivor survivors from NP chunking survivor peo2:syncytiotrophoblast_cell plasmidotrophoblast syncytial trophoblast syntrophoblast syncytiotrophoblast cell peo2:thing_related_to_biological_functions thing related to biological functions peo2:thing_related_to_complication_for_child thing related to complication for child peo2:thing_related_to_complications thing related to complications peo2:thing_related_to_complications_for_mother thing related to complications for mother peo2:thing_related_to_demographics thing related to demographics peo2:thing_related_to_early_onset EO Early onset thing related to early onset peo2:thing_related_to_economic_status thing related to economic status peo2:thing_related_to_environmental_exposure thing related to environmental exposure peo2:thing_related_to_functional_phenotypes thing related to functional phenotypes peo2:thing_related_to_functional_units thing related to functional units peo2:thing_related_to_gene gene genes thing related to gene peo2:thing_related_to_history_of_obestric_complications thing related to history of obestric complications peo2:thing_related_to_late_onset LO Late onset Late-onset thing related to late onset peo2:thing_related_to_lifestyle thing related to lifestyle peo2:thing_related_to_main_complaint thing related to main complaint peo2:thing_related_to_medical_history thing related to medical history peo2:thing_related_to_medical_resources thing related to medical resources peo2:thing_related_to_medicational_history thing related to medicational history peo2:thing_related_to_mild_stage mild thing related to mild stage peo2:thing_related_to_observations thing related to observations peo2:thing_related_to_outcome_of_child thing related to outcome of child peo2:thing_related_to_outcome_of_mother thing related to outcome of mother peo2:thing_related_to_outcomes thing related to outcomes peo2:thing_related_to_past_physical_status thing related to past physical status peo2:thing_related_to_past_treatment thing related to past treatment peo2:thing_related_to_phenotypic_features thing related to phenotypic features peo2:thing_related_to_precursor thing related to precursor peo2:thing_related_to_protein thing related to protein peo2:thing_related_to_regional_status thing related to regional status peo2:thing_related_to_severe_stage severe thing related to severe stage peo2:thing_related_to_social_factors thing related to social factors peo2:thing_related_to_social_support thing related to social support peo2:thing_related_to_stage Stage stages thing related to stage peo2:thing_related_to_transcript thing related to transcript peo2:thing_related_to_variants genetic risk factor genetic risk factors thing related to variants peo2:thing_that_acts_as_a_genetic_biomarker genetic biomarker thing that acts as a genetic biomarker peo2:thing_that_can_increase_the_risk thing that can increase the risk peo2:trans-Golgi_Network Network, trans-Golgi Region, trans-Golgi Regions, trans-Golgi trans Golgi Network trans Golgi Region trans-Golgi Region trans-Golgi Regions http://purl.bioontology.org/ontology/MESH/D021601 A network of membrane compartments, located at the cytoplasmic side of the GOLGI APPARATUS, where proteins and lipids are sorted for transport to various locations in the cell or cell membrane. trans-Golgi Network peo2:treatment_at_delivery treatment at delivery peo2:treatment_during_pregnancy treatment during pregnancy peo2:triglyceride C6H5O6R3 Triacylglycerol Triglycerid Triglyceride Triglyzerid [*]C(=O)OCC(COC([*])=O)OC([*])=O a triacylglycerol triacylglycerols triglycerides http://purl.obolibrary.org/obo/CHEBI_17855 triglyceride peo2:triglyceride-rich_lipoprotein triglyceride-rich lipoprotein peo2:type_2_immune_response T-helper 2 type immune response Th2 immune response http://purl.obolibrary.org/obo/GO_0042092 An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. type 2 immune response peo2:vacular_inflammation inflammation of vessel from manual annotation of text corpus vascular inflammation peo2:very-low-density_lipoprotein_cholesterol VLDL cholesterol VLDL-C pre-beta-lipoprotein cholesterol http://purl.obolibrary.org/obo/CHEBI_47773 Cholesterol esters and free cholesterol which are contained in or bound to very low density lipoproteins (VLDL). very-low-density lipoprotein cholesterol peo2:vitamin vitamins http://purl.obolibrary.org/obo/CHEBI_33229 vitamin peo2:vitamin_C Vitamin C vitamina C vitamine C vitaminum C http://purl.obolibrary.org/obo/CHEBI_21241 Vitamin C peo2:vitamin_D D vitamins vitamin Ds http://purl.obolibrary.org/obo/CHEBI_27300 Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body. vitamin D peo2:wk16_20 16-20 wk peo2:wk28 28 wk peo2:wk36 peo2:wk8_10 8–10 wk peo2:wnt_signalling wingless signalling wnt-signalling from manual annotation of text corpus wnt signalling peo2:younger_than_marriageable_age adolescents of <17 years old biological immature younger than marriageable age peo2:zinc Zn from manual annotation of text corpus Gave up before pregnancy (Alcohol intake) Gave up during pregnancy (Alcohol intake) peo2:HDL_ratio_measurement Total cholesterol:HDL ratio Total cholesterol:high density lipoprotein ratio measurement Total cholesterol:high density lipoprotein ratio measurement (procedure) http://purl.bioontology.org/ontology/SNOMEDCT/166842003 Total cholesterol:HDL ratio measurement owl:Thing 1.1.1 v0.2 v15 Heneka comments / shifs / modifications integrated Caffeine consumption neuronal damage Transporter Alan Ruttenberg Andrew Spear Michaela Guendel Pierre Grenon Ashutosh Erfan Younesi Holger Stenzhorn Michaela Guendel Satoshi Mizuno 12.9.11 20.02.12 application/rdf+xml http://www.ifomis.org/bfo/1.1 en Institute for Formal Ontology and Medical Information Science (IFOMIS) http://creativecommons.org/licenses/by/3.0 Barry Smith and Pierre Grenon: "The Cornucopia of Formal Ontological Relations" Barry Smith: "Against Fantology" Barry Smith: "Basic Tools of Formal Ontology" Barry Smith: "Beyond Concepts: Ontology as Reality Representation" Pierre Grenon and Barry Smith: "SNAP and SPAN: Towards Geospatial Dynamics" Pierre Grenon, Barry Smith and Louis Goldberg: "Biodynamic Ontology: Applying BFO in the Biomedical Domain" Pierre Grenon: "BFO in a Nutshell: A Bi-categorial Axiomatization of BFO and Comparison with DOLCE" Pierre Grenon: "Nuts in BFO's Nutshell: Revisions to the Bi-categorial Axiomatization of BFO" Pierre Grenon: "Spatio-temporality in Basic Formal Ontology: SNAP and SPAN, Upper-Level Ontology, and Framework for Formalization" Basic Formal Ontology (BFO) Alzheimer Ontology proposed upper view ontology for neurodegenerative diseases v0.1 v14 1.1.1 v0.2 v15 Heneka comments / shifs / modifications integrated