alaynecuzick 2018-07-09T13:43:00Z Ontology of species-neutral phenotypes observed in pathogen-host interactions. Pathogen Host Interactions Phenotype Ontology https://creativecommons.org/licenses/by/3.0/ 2024-08-29 definition The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition definition textual definition If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL is a defining property chain axiom If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R. is a defining property chain axiom where second argument is reflexive created by creation date has_alternative_id An alternative label for a class or property which has a more general meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/18 has broad synonym has_broad_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/18 database_cross_reference An alternative label for a class or property which has the exact same meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/20 has exact synonym has_exact_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/20 An alternative label for a class or property which has a more specific meaning than the preferred name/primary label. https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has narrow synonym has_narrow_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/19 has_obo_namespace An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct. https://github.com/information-artifact-ontology/ontology-metadata/issues/21 has related synonym has_related_synonym https://github.com/information-artifact-ontology/ontology-metadata/issues/21 id in_subset is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) this day is part of this year (occurrent parthood) a core relation that holds between a part and its whole Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. part_of BFO:0000050 external quality part_of part_of part of part of part_of http://www.obofoundry.org/ro/#OBO_REL:part_of https://wiki.geneontology.org/Part_of realized in this disease is realized in this disease course this fragility is realized in this shattering this investigator role is realized in this investigation is realized by realized_in [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process realized in realizes this disease course realizes this disease this investigation realizes this investigator role this shattering realizes this fragility to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003]) Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process realizes site of [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant contains process results_in alaynecuzick 2018-10-12T13:24:02Z Used in FYPO as described in PATO best practices; placeholder relation to indicate normality/abnormality. which namespace? do we need all 3 triplicated again? qualifier inheres in this fragility inheres in this vase this fragility is a characteristic of this vase this red color inheres in this apple this red color is a characteristic of this apple a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence A dependent inheres in its bearer at all times for which the dependent exists. inheres_in Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing. characteristic of inheres in participates in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation a relation between a continuant and a process, in which the continuant is somehow involved in the process participates_in RO:0000056 external participates_in participates_in participates in participates in has participant this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) a relation between a process and a continuant, in which the continuant is somehow involved in the process Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. has_participant http://www.obofoundry.org/ro/#OBO_REL:has_participant RO:0000057 external has_participant has_participant has participant has participant this catalysis function is a function of this enzyme a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists. function_of is function of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. function of this red color is a quality of this apple a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence A quality inheres in its bearer at all times for which the quality exists. is quality of quality_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. quality of this investigator role is a role of this person a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists. is role of role_of This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. role of this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function) a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists. has_function has function inverse of has disposition This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. disposition of A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. 2017-05-24T09:30:46Z RO:0002013 external has_regulatory_component_activity has_regulatory_component_activity has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. 2017-05-24T09:31:01Z RO:0002014 external has_negative_regulatory_component_activity has_negative_regulatory_component_activity By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. has negative regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. 2017-05-24T09:31:17Z By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. has positive regulatory component activity 2017-05-24T09:44:33Z A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. has component activity w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. 2017-05-24T09:49:21Z has component process 2017-09-17T13:52:24Z Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. directly regulated by Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. 2017-09-17T13:52:38Z directly negatively regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. 2017-09-17T13:52:47Z directly positively regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. 2017-09-22T14:14:36Z This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. has effector activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. David Osumi-Sutherland <= Primitive instance level timing relation between events before or simultaneous with David Osumi-Sutherland X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) ends after David Osumi-Sutherland starts_at_end_of RO:0002087 external immediately_preceded_by immediately_preceded_by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) immediately preceded by immediately preceded by David Osumi-Sutherland ends_at_start_of meets RO:0002090 external immediately_precedes immediately_precedes X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) immediately precedes immediately precedes x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) RO:0002131 external overlaps overlaps overlaps overlaps true x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. Connects a biological entity to its taxon of origin. in taxon w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity. For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit. RO:0002180 external has_component has_component has component has component c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. has function in RO:0002216 external capable_of_part_of capable_of_part_of capable of part of capable of part of true Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends. https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. temporally related to x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y starts with process that occurs in RO:0002231 external has_start_location has_start_location has start location has start location x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y ends with process that occurs in RO:0002232 external has_end_location has_end_location has end location has end location p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. consumes RO:0002233 external has_input has_input has input has input https://wiki.geneontology.org/Has_input p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. produces RO:0002234 external has_output has_output has output has output https://wiki.geneontology.org/Has_output A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision. c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. acts upstream of A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway. c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. affects acts upstream of or within https://wiki.geneontology.org/Acts_upstream_of_or_within p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. RO:0002304 external causally_upstream_of,_positive_effect causally_upstream_of,_positive_effect holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y causally upstream of, positive effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. RO:0002305 external causally_upstream_of,_negative_effect causally_upstream_of,_negative_effect causally upstream of, negative effect q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. Because part_of is transitive, inheres in is a sub-relation of characteristic of part of inheres in part of characteristic of part of true A relationship that holds via some environmental process Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution. evolutionarily related to A mereological relationship or a topological relationship Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships mereotopologically related to A relationship that holds between entities participating in some developmental process (GO:0032502) Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development developmentally related to a particular instances of akt-2 enables some instance of protein kinase activity c enables p iff c is capable of p and c acts to execute p. catalyzes executes has is catalyzing is executing This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized. enables https://wiki.geneontology.org/Enables A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. This is a grouping relation that collects relations used for the purpose of connecting structure and function functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. false part of structure that is capable of true c involved_in p if and only if c enables some process p', and p' is part of p actively involved in enables part of involved in https://wiki.geneontology.org/Involved_in inverse of enables enabled by https://wiki.geneontology.org/Enabled_by inverse of regulates regulated by (processual) RO:0002334 external regulated_by regulated_by regulated by regulated by inverse of negatively regulates RO:0002335 external negatively_regulated_by negatively_regulated_by negatively regulated by negatively regulated by inverse of positively regulates RO:0002336 external positively_regulated_by positively_regulated_by positively regulated by positively regulated by A relationship that holds via some process of localization Do not use this relation directly. It is a grouping relation. related via localization to inverse of has input input of inverse of has output RO:0002353 external output_of output_of output of output of formed as result of inverse of upstream of RO:0002404 external causally_downstream_of causally_downstream_of causally downstream of causally downstream of RO:0002405 external immediately_causally_downstream_of immediately_causally_downstream_of immediately causally downstream of immediately causally downstream of p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q. indirectly activates indirectly positively regulates https://wiki.geneontology.org/Indirectly_positively_regulates p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q. indirectly inhibits indirectly negatively regulates https://wiki.geneontology.org/Indirectly_negatively_regulates relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yield a cross-product of different relation types. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. https://en.wikipedia.org/wiki/Causality p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. RO:0002411 external causally_upstream_of causally_upstream_of causally upstream of causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. RO:0002412 external immediately_causally_upstream_of immediately_causally_upstream_of immediately causally upstream of immediately causally upstream of p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2 influences (processual) RO:0002418 external affects causally_upstream_of_or_within causally_upstream_of_or_within causally upstream of or within inverse of causally upstream of or within RO:0002427 external causally_downstream_of_or_within causally_downstream_of_or_within causally downstream of or within c involved in regulation of p if c is involved in some p' and p' regulates some p involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p involved in positive regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p involved in negative regulation of c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p OWL does not allow defining object properties via a Union involved in or reguates involved in or involved in regulation of A protein that enables activity in a cytosol. c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. executes activity in enables activity in is active in https://wiki.geneontology.org/Is_active_in true c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. A relationship that holds between two entities in which the processes executed by the two entities are causally connected. Considering relabeling as 'pairwise interacts with' This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact. Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules. in pairwise interaction with interacts with http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ http://purl.obolibrary.org/obo/MI_0914 An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. binds molecularly binds with molecularly interacts with http://purl.obolibrary.org/obo/MI_0915 Axiomatization to GO to be added later An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y. phosphorylates The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. molecularly controls directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. directly inhibits molecularly decreases activity of directly negatively regulates activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. directly activates molecularly increases activity of directly positively regulates activity of This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning. helper property (not for use in curation) p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. has part that occurs in true is kinase activity Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage. relation between physical entity and a process or stage x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). existence starts during x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence overlaps x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence starts during or after A relationship between a material entity and a process where the material entity has some causal role that influences the process causal agent in process p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between processes depends on q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2 This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C. towards The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between entities causally influenced by (entity-centric) causally influenced by interaction relation helper property http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ molecular interaction relation helper property The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). causally influences (entity-centric) causally influences A relation that holds between an attribute or a qualifier and another attribute. This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the "modifiers" are. has modifier p directly regulates q iff p is immediately causally upstream of q and p regulates q. directly regulates (processual) RO:0002578 external directly_regulates directly_regulates directly regulates gland SubClassOf 'has part structure that is capable of' some 'secretion by cell' s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p has part structure that is capable of p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p results in breakdown of A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causal relation between material entity and a process pyrethroid -> growth Holds between c and p if and only if c is capable of some activity a, and a regulates p. capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. capable of negatively regulating renin -> arteriolar smooth muscle contraction Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. capable of positively regulating Inverse of 'causal agent in process' RO:0002608 external process_has_causal_agent process_has_causal_agent process has causal agent p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q. directly positively regulates (process to process) RO:0002629 external directly_positively_regulates directly_positively_regulates directly positively regulates https://wiki.geneontology.org/Directly_positively_regulates p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q. directly negatively regulates (process to process) RO:0002630 external directly_negatively_regulates directly_negatively_regulates directly negatively regulates https://wiki.geneontology.org/Directly_negatively_regulates a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. RO:0003000 external produces produces Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue. produces produces a produced_by b iff some process that occurs_in b has_output a. RO:0003001 external produced_by produced_by produced by produced by Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. 2018-01-25T23:20:13Z enables subfunction 2018-01-26T23:49:30Z acts upstream of or within, positive effect https://wiki.geneontology.org/Acts_upstream_of_or_within,_positive_effect 2018-01-26T23:49:51Z acts upstream of or within, negative effect https://wiki.geneontology.org/Acts_upstream_of_or_within,_negative_effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive 2018-01-26T23:53:14Z acts upstream of, positive effect https://wiki.geneontology.org/Acts_upstream_of,_positive_effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative 2018-01-26T23:53:22Z acts upstream of, negative effect https://wiki.geneontology.org/Acts_upstream_of,_negative_effect 2018-03-13T23:55:05Z causally upstream of or within, negative effect https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect 2018-03-13T23:55:19Z causally upstream of or within, positive effect The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. regulates activity of p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q. 2022-09-26T06:07:17Z indirectly causally upstream of p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q. 2022-09-26T06:08:01Z indirectly regulates q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 A diagnostic testing device utilizes a specimen. X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input. See github ticket https://github.com/oborel/obo-relations/issues/497 2021-11-08T12:00:00Z utilizes device utilizes material A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C. RO:0019000 gene_ontology regulates_characteristic regulates_characteristic regulates characteristic A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C. RO:0019001 gene_ontology positively_regulates_characteristic positively_regulates_characteristic positively regulates characteristic A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C. RO:0019002 gene_ontology negatively_regulates_characteristic negatively_regulates_characteristic negatively regulates characteristic p has anatomical participant c iff p has participant c, and c is an anatomical entity 2018-09-26T01:08:58Z RO:0040036 external results_in_changes_to_anatomical_or_cellular_structure results_in_changes_to_anatomical_or_cellular_structure results in changes to anatomical or cellular structure OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015008 quality decreased_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454 for obsoletion reason. This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'. obsolete decreased_in_magnitude_relative_to true OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM RO:0015010 quality has_relative_magnitude Refer to https://github.com/pato-ontology/pato/issues/454. obsolete has_relative_magnitude true OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. RO:0015007 quality increased_in_magnitude_relative_to Refer to https://github.com/pato-ontology/pato/issues/454. This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. obsolete increased_in_magnitude_relative_to true OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. PATOC:CJM RO:0002503 quality towards Consider using RO:0002503 instead. See https://github.com/pato-ontology/pato/issues/454 obsolete towards true Inverse of part_of. sequence has_part Example: operon has_part gene. has_part Inverse of part_of. http://precedings.nature.com/documents/3495/version/1 BFO:0000001 entity Entity Julius Caesar Verdi’s Requiem the Second World War your body mass index BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) entity Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf per discussion with Barry Smith An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) BFO:0000002 continuant Continuant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] continuant Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] BFO:0000003 occurrent Occurrent An entity that has temporal parts and that happens, unfolds or develops through time. BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] occurrent Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. per discussion with Barry Smith Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] BFO:0000004 ic IndependentContinuant a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism the bottom right portion of a human torso the interior of your mouth A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. independent continuant b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] BFO:0000015 process Process a process of cell-division, \ a beating of the heart a process of meiosis a process of sleeping the course of a disease the flight of a bird the life of an organism your process of aging. An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. process p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] BFO:0000016 disposition Disposition an atom of element X has the disposition to decay to an atom of element Y certain people have a predisposition to colon cancer children are innately disposed to categorize objects in certain ways. the cell wall is disposed to filter chemicals in endocytosis and exocytosis BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] disposition b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] BFO:0000017 realizable RealizableEntity the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of being a doctor the role of this boundary to delineate where Utah and Colorado meet A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] realizable realizable entity To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] BFO:0000019 quality BFO:0000020 sdc SpecificallyDependentContinuant Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. characteristic specifically dependent continuant https://github.com/OBOFoundry/COB/issues/65 https://github.com/oborel/obo-relations/pull/284 b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i &lt; j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. per discussion with Barry Smith (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] BFO:0000023 A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. role BFO:0000031 gdc GenericallyDependentContinuant The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] generically dependent continuant b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] BFO:0000034 function BFO:0000040 material MaterialEntity a flame a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic the undetached arm of a human being An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] material entity A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] CARO:0000000 A part of a multicellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a multicellular organism with granularity above the level of a protein complex. anatomical entity CARO:0010004 A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. 0 C12H12N2O3 InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17) MHWLWQUZZRMNGJ-UHFFFAOYSA-N 232.23530 232.08479 CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12 CHEBI:7456 CAS:389-08-2 DrugBank:DB00779 Drug_Central:1875 KEGG:C05079 KEGG:D00183 LINCS:LSM-5590 PDBeChem:NIX PMID:11321869 PMID:12002106 PMID:12399485 PMID:12702698 PMID:14107587 PMID:16107187 PMID:16423473 PMID:16667857 PMID:16803589 PMID:17132068 PMID:17631104 PMID:18788798 PMID:19071706 PMID:28166217 Patent:BE612258 Patent:US3590036 Reaxys:750515 VSDB:1880 Wikipedia:Nalidixic_Acid 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid NALIDIXIC ACID Nalidixic acid chebi_ontology 1,4-dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one acide nalidixique acido nalidixico acidum nalidixicum nalidixic acid CHEBI:100147 nalidixic acid CHEBI:100147 CAS:389-08-2 ChemIDplus CAS:389-08-2 KEGG COMPOUND Drug_Central:1875 DrugCentral PMID:11321869 Europe PMC PMID:12002106 Europe PMC PMID:12399485 Europe PMC PMID:12702698 Europe PMC PMID:14107587 Europe PMC PMID:16107187 Europe PMC PMID:16423473 Europe PMC PMID:16667857 Europe PMC PMID:16803589 Europe PMC PMID:17132068 Europe PMC PMID:17631104 Europe PMC PMID:18788798 Europe PMC PMID:19071706 Europe PMC PMID:28166217 Europe PMC Reaxys:750515 Reaxys 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid IUPAC NALIDIXIC ACID ChEMBL Nalidixic acid KEGG_COMPOUND 1,4-dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ChemIDplus 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ChemIDplus 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ChEMBL 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ChemIDplus 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid ChemIDplus 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ChemIDplus acide nalidixique ChemIDplus acido nalidixico ChemIDplus acidum nalidixicum ChemIDplus nalidixic acid ChemIDplus A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination. 0 C15H20O6 InChI=1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1 LINOMUASTDIRTM-QGRHZQQGSA-N 296.319 296.12599 [H][C@@]12O[C@]3([H])C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@@](C)(C[C@H]1O)[C@]21CO1 CAS:51481-10-8 Chemspider:36584 KEGG:C09747 KNApSAcK:C00003201 LIPID_MAPS_instance:LMPR0103180002 PMID:28780485 PMID:30284112 PMID:30714884 PMID:30760085 PMID:30802751 PMID:30806951 PMID:30841652 PMID:31394401 PMID:31817218 PMID:31867960 PMID:31960350 PMID:32218143 PMID:32260237 PMID:32560237 PMID:32745571 PMID:32805342 PMID:32851525 PMID:32880717 PMID:32930227 Wikipedia:Vomitoxin 3alpha,7alpha,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one chebi_ontology 3alpha,7alpha,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one 4-Deoxynivalenol 4-Desoxynivalenol DON Dehydronivalenol Desoxynivalenol Vomitoxin CHEBI:10022 deoxynivalenol CHEBI:10022 CAS:51481-10-8 ChemIDplus CAS:51481-10-8 KEGG COMPOUND LIPID_MAPS_instance:LMPR0103180002 LIPID MAPS PMID:28780485 Europe PMC PMID:30284112 Europe PMC PMID:30714884 Europe PMC PMID:30760085 Europe PMC PMID:30802751 Europe PMC PMID:30806951 Europe PMC PMID:30841652 Europe PMC PMID:31394401 Europe PMC PMID:31817218 Europe PMC PMID:31867960 Europe PMC PMID:31960350 Europe PMC PMID:32218143 Europe PMC PMID:32260237 Europe PMC PMID:32560237 Europe PMC PMID:32745571 Europe PMC PMID:32805342 Europe PMC PMID:32851525 Europe PMC PMID:32880717 Europe PMC PMID:32930227 Europe PMC 3alpha,7alpha,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one IUPAC 3alpha,7alpha,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one ChemIDplus 4-Deoxynivalenol ChemIDplus 4-Desoxynivalenol ChemIDplus DON KEGG_COMPOUND Dehydronivalenol ChemIDplus Desoxynivalenol ChemIDplus Vomitoxin KEGG_COMPOUND A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4. 0 C16H14F3N5O InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1 BCEHBSKCWLPMDN-MGPLVRAMSA-N 349.31050 349.11504 C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F CHEBI:127308 Beilstein:7694998 CAS:137234-62-9 DrugBank:DB00582 Drug_Central:2846 KEGG:C07622 KEGG:D00578 LINCS:LSM-5244 PMID:12940129 PMID:22718362 PMID:23392902 PMID:23527908 PMID:23766489 PMID:24102553 Patent:EP440372 Patent:US5278175 Wikipedia:Voriconazole (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol voriconazole chebi_ontology (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol VCZ Vfend voriconazol voriconazole voriconazolum CHEBI:10023 voriconazole CHEBI:10023 Beilstein:7694998 Beilstein CAS:137234-62-9 ChemIDplus CAS:137234-62-9 DrugBank CAS:137234-62-9 KEGG COMPOUND CAS:137234-62-9 KEGG DRUG Drug_Central:2846 DrugCentral PMID:12940129 Europe PMC PMID:22718362 Europe PMC PMID:23392902 Europe PMC PMID:23527908 Europe PMC PMID:23766489 Europe PMC PMID:24102553 Europe PMC (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC voriconazole UniProt (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ChEBI (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ChemIDplus VCZ DrugBank Vfend ChEBI voriconazol WHO_MedNet voriconazole ChemIDplus voriconazole WHO_MedNet voriconazolum WHO_MedNet A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. 0 C17H18FN3O3 InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24) MYSWGUAQZAJSOK-UHFFFAOYSA-N 331.34150 331.13322 OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O CHEBI:102718 CHEBI:3717 CHEBI:41638 Beilstein:3568352 CAS:85721-33-1 DrugBank:DB00537 Drug_Central:659 HMDB:HMDB0014677 KEGG:C05349 KEGG:D00186 LINCS:LSM-5226 PDBeChem:CPF PMID:10397494 PMID:10737746 Patent:DE3142854 Patent:US4670444 Reaxys:3568352 VSDB:1763 Wikipedia:Ciprofloxacin 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid Ciprofloxacin ciprofloxacin chebi_ontology 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ciprofloxacin ciprofloxacine ciprofloxacino ciprofloxacinum CHEBI:100241 ciprofloxacin CHEBI:100241 Beilstein:3568352 Beilstein CAS:85721-33-1 ChemIDplus CAS:85721-33-1 KEGG COMPOUND Drug_Central:659 DrugCentral PMID:10397494 ChEMBL PMID:10737746 ChEMBL Reaxys:3568352 Reaxys 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid IUPAC Ciprofloxacin KEGG_COMPOUND ciprofloxacin ChEMBL 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID PDBeChem 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid ChEMBL 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ChEMBL 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ChemIDplus 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid ChEMBL 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ChEMBL 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ChEMBL ciprofloxacin ChemIDplus ciprofloxacine ChemIDplus ciprofloxacino ChemIDplus ciprofloxacinum ChemIDplus A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. 0 C16H18FN3O3 InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23) OGJPXUAPXNRGGI-UHFFFAOYSA-N 319.33080 319.13322 CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1 CHEBI:7629 Beilstein:567897 CAS:70458-96-7 DrugBank:DB01059 Drug_Central:1967 Gmelin:1576626 HMDB:HMDB0015192 KEGG:C06687 KEGG:D00210 LINCS:LSM-5286 PMID:3317294 PMID:3908074 PMID:6211142 PMID:6224685 PMID:6234465 PMID:6454381 PMID:6461606 Patent:BE863429 Patent:DE2840910 Patent:US4146719 Patent:US4292317 Reaxys:567897 VSDB:1831 Wikipedia:Norfloxacin 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid chebi_ontology 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid NFLX norfloxacin norfloxacine norfloxacino norfloxacinum CHEBI:100246 norfloxacin CHEBI:100246 Beilstein:567897 Beilstein CAS:70458-96-7 ChemIDplus CAS:70458-96-7 KEGG COMPOUND Drug_Central:1967 DrugCentral Gmelin:1576626 Gmelin PMID:3317294 Europe PMC PMID:3908074 Europe PMC PMID:6211142 Europe PMC PMID:6224685 Europe PMC PMID:6234465 Europe PMC PMID:6454381 Europe PMC PMID:6461606 Europe PMC Reaxys:567897 Reaxys 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid IUPAC 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ChemIDplus 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure ChemIDplus 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ChemIDplus NFLX KEGG_DRUG norfloxacin KEGG_DRUG norfloxacine ChemIDplus norfloxacino ChemIDplus norfloxacinum ChemIDplus A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. 0 C11H13N3O3S InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3 NHUHCSRWZMLRLA-UHFFFAOYSA-N 267.30400 267.06776 Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C CHEBI:9343 Beilstein:263871 CAS:127-69-5 DrugBank:DB00263 Drug_Central:2529 Gmelin:864477 KEGG:C07318 KEGG:D00450 LINCS:LSM-3120 PMID:1861917 PMID:4960234 PMID:7356572 Patent:US2430094 Wikipedia:Sulfisoxazole 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide chebi_ontology 3,4-Dimethyl-5-sulfanilamidoisoxazole 3,4-Dimethyl-5-sulfonamidoisoxazole 3,4-Dimethyl-5-sulphanilamidoisoxazole 3,4-Dimethyl-5-sulphonamidoisoxazole 3,4-Dimethylisoxazole-5-sulfanilamide 3,4-Dimethylisoxazole-5-sulphanilamide 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole 5-Sulfanilamido-3,4-dimethylisoxazole 5-Sulphanilamido-3,4-dimethyl-isoxazole N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide Sulfadimethylisoxazole Sulfafurazol Sulfaisoxazole Sulfasoxazole Sulfisonazole Sulfisoxasole Sulfisoxazol Sulfofurazole Sulphadimethylisoxazole Sulphafurazol Sulphafurazole Sulphaisoxazole Sulphisoxazol Sulphofurazole sulfafurazole sulfafurazolum CHEBI:102484 sulfisoxazole CHEBI:102484 Beilstein:263871 Beilstein CAS:127-69-5 ChemIDplus CAS:127-69-5 NIST Chemistry WebBook Drug_Central:2529 DrugCentral Gmelin:864477 Gmelin PMID:1861917 Europe PMC PMID:4960234 Europe PMC PMID:7356572 Europe PMC 4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide IUPAC 3,4-Dimethyl-5-sulfanilamidoisoxazole ChemIDplus 3,4-Dimethyl-5-sulfonamidoisoxazole ChemIDplus 3,4-Dimethyl-5-sulphanilamidoisoxazole ChemIDplus 3,4-Dimethyl-5-sulphonamidoisoxazole ChemIDplus 3,4-Dimethylisoxazole-5-sulfanilamide ChemIDplus 3,4-Dimethylisoxazole-5-sulphanilamide ChemIDplus 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide NIST_Chemistry_WebBook 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide ChemIDplus 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole ChemIDplus 5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole ChemIDplus 5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole ChemIDplus 5-Sulfanilamido-3,4-dimethylisoxazole ChemIDplus 5-Sulphanilamido-3,4-dimethyl-isoxazole ChemIDplus N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide ChemIDplus N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide ChemIDplus N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide ChemIDplus Sulfadimethylisoxazole DrugBank Sulfafurazol DrugBank Sulfaisoxazole DrugBank Sulfasoxazole DrugBank Sulfisonazole DrugBank Sulfisoxasole DrugBank Sulfisoxazol DrugBank Sulfofurazole DrugBank Sulphadimethylisoxazole NIST_Chemistry_WebBook Sulphafurazol DrugBank Sulphafurazole DrugBank Sulphaisoxazole DrugBank Sulphisoxazol DrugBank Sulphofurazole DrugBank sulfafurazole KEGG_DRUG sulfafurazolum ChemIDplus Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. -1 0.000548579903 0.0 KEGG:C05359 PMID:21614077 Wikipedia:Electron electron chebi_ontology Elektron beta beta(-) beta-particle e e(-) e- negatron CHEBI:10545 electron CHEBI:10545 PMID:21614077 Europe PMC electron ChEBI electron IUPAC electron KEGG_COMPOUND Elektron ChEBI beta IUPAC beta(-) ChEBI beta-particle IUPAC e IUPAC e(-) UniProt e- KEGG_COMPOUND negatron IUPAC 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3+,4+,5-,6- CDAISMWEOUEBRE-CDRYSYESSA-N 180.15588 180.06339 O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O CHEBI:26614 Beilstein:2206312 CAS:488-59-5 Gmelin:561300 KEGG:C06153 PMID:24352657 Reaxys:2206312 scyllo-Inositol scyllo-inositol chebi_ontology (1r,2r,3r,4r,5r,6r)-cyclohexane-1,2,3,4,5,6-hexol 1,3,5/2,4,6-cyclohexanehexol Cocositol Quercinitol Scyllitol CHEBI:10642 scyllo-inositol CHEBI:10642 Beilstein:2206312 Beilstein CAS:488-59-5 ChemIDplus CAS:488-59-5 KEGG COMPOUND CAS:488-59-5 NIST Chemistry WebBook Gmelin:561300 Gmelin PMID:24352657 Europe PMC Reaxys:2206312 Reaxys scyllo-Inositol KEGG_COMPOUND scyllo-inositol IUPAC scyllo-inositol UniProt (1r,2r,3r,4r,5r,6r)-cyclohexane-1,2,3,4,5,6-hexol IUPAC 1,3,5/2,4,6-cyclohexanehexol IUPAC Cocositol NIST_Chemistry_WebBook Quercinitol ChemIDplus Scyllitol ChemIDplus An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin. PMID:26717596 chebi_ontology CHEBI:130181 calmodulin antagonist CHEBI:130181 PMID:26717596 Europe PMC Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. chebi_ontology Mycoplasma genitalium metabolites CHEBI:131604 Mycoplasma genitalium metabolite CHEBI:131604 Mycoplasma genitalium metabolites ChEBI A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester. chebi_ontology CHEBI:131605 dicarboxylic acid monoester(1-) CHEBI:131605 An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin. 0 C50H80N8O17 InChI=1S/C50H80N8O17/c1-5-25(2)20-26(3)12-10-8-6-7-9-11-13-37(66)52-31-22-35(64)46(71)56-48(73)41-33(62)18-19-57(41)50(75)39(34(63)23-36(51)65)54-47(72)40(43(68)42(67)28-14-16-29(60)17-15-28)55-45(70)32-21-30(61)24-58(32)49(74)38(27(4)59)53-44(31)69/h14-17,25-27,30-35,38-43,46,59-64,67-68,71H,5-13,18-24H2,1-4H3,(H2,51,65)(H,52,66)(H,53,69)(H,54,72)(H,55,70)(H,56,73)/t25-,26+,27+,30+,31-,32-,33-,34+,35+,38-,39-,40-,41-,42-,43-,46+/m0/s1 DQXPFAADCTZLNL-FXDJFZINSA-N 1065.216 1064.56414 [C@@]12(N(C[C@@H](C1)O)C([C@H]([C@@H](C)O)NC(=O)[C@](C[C@H]([C@@H](O)NC([C@@H]3[C@H](CCN3C([C@H]([C@@H](CC(N)=O)O)NC(=O)[C@H]([C@@H]([C@H](C4=CC=C(C=C4)O)O)O)NC2=O)=O)O)=O)O)(NC(CCCCCCCC[C@H](C[C@H](CC)C)C)=O)[H])=O)[H] CAS:135575-42-7 PMID:24086376 PMID:24270605 PMID:25527531 Reaxys:9316734 Wikipedia:Pneumocandin_Bo (10R,12S)-N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide chebi_ontology L 688,786 L-688,786 L-688786 pneumocandin B(0) pneumocardin B(0) CHEBI:131609 pneumocandin B0 CHEBI:131609 CAS:135575-42-7 ChemIDplus PMID:24086376 Europe PMC PMID:24270605 Europe PMC PMID:25527531 Europe PMC Reaxys:9316734 Reaxys (10R,12S)-N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide IUPAC L 688,786 ChemIDplus L-688,786 ChemIDplus L-688786 ChemIDplus pneumocandin B(0) ChemIDplus pneumocardin B(0) ChemIDplus Any polyunsaturated fatty acid anion carrying one or more hydroxy substituents. -1 CHO3R 61.017 60.99257 O*C([O-])=O chebi_ontology a hydroxy polyunsaturated fatty acid hydroxy PUFA hydroxy polyunsaturated fatty acid anions CHEBI:131871 hydroxy polyunsaturated fatty acid anion CHEBI:131871 a hydroxy polyunsaturated fatty acid UniProt hydroxy PUFA SUBMITTER hydroxy polyunsaturated fatty acid anions ChEBI A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. chebi_ontology dicarboxylic acids and derivatives CHEBI:131927 dicarboxylic acids and O-substituted derivatives CHEBI:131927 dicarboxylic acids and derivatives ChEBI Any quinone in which one or more of the carbons making up the quinone moiety is substituted by a hydroxy group. chebi_ontology hydroxyquinones CHEBI:132130 hydroxyquinone CHEBI:132130 hydroxyquinones ChEBI A naphthoquinone in which the oxo groups of the quinone moiety are at positions 1 and 4 of the parent naphthalene ring. chebi_ontology CHEBI:132142 1,4-naphthoquinones CHEBI:132142 Any naphthoquinone in which the naphthaoquinone moiety is substituted by at least one hydroxy group. Wikipedia:Hydroxynaphthoquinone chebi_ontology hydroxynaphthoquinones CHEBI:132155 hydroxynaphthoquinone CHEBI:132155 hydroxynaphthoquinones ChEBI Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group. chebi_ontology hydroxy-1,4-naphthoquinones CHEBI:132157 hydroxy-1,4-naphthoquinone CHEBI:132157 hydroxy-1,4-naphthoquinones ChEBI Any aromatic amide obtained by acylation of aniline. 0 C7H6NOR 120.12860 120.04494 [*]C(=O)Nc1ccccc1 KEGG:C01402 PMID:23535982 PMID:23968552 PMID:24273122 PMID:6205897 chebi_ontology N-phenyl amide N-phenyl amides an anilide CHEBI:13248 anilide CHEBI:13248 PMID:23535982 Europe PMC PMID:23968552 Europe PMC PMID:24273122 Europe PMC PMID:6205897 Europe PMC N-phenyl amide ChEBI N-phenyl amides ChEBI an anilide UniProt A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties. Wikipedia:Bleach chebi_ontology CHEBI:132717 bleaching agent CHEBI:132717 A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the adjacent tertiary amino group of oxytetracycline; major species at pH 7.3. 0 C22H24N2O9 InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1 IWVCMVBTMGNXQD-PXOLEDIWSA-N 460.435 460.14818 [C@@]12([C@](C(=C3C(C=4C(=CC=CC4[C@@]([C@]3([C@@H]1O)[H])(C)O)O)=O)O)(C(C(C(N)=O)=C([C@H]2[NH+](C)C)[O-])=O)O)[H] MetaCyc:CPD-19255 (1S,4aS,11S,11aR,12S,12aR)-3-carbamoyl-1-(dimethylazaniumyl)-4a,5,7,11,12-pentahydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate chebi_ontology oxytetracycline CHEBI:133011 oxytetracycline zwitterion CHEBI:133011 (1S,4aS,11S,11aR,12S,12aR)-3-carbamoyl-1-(dimethylazaniumyl)-4a,5,7,11,12-pentahydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate IUPAC oxytetracycline UniProt Any organic heteroolycyclic compound whose skeleton two ortho-fused chromene rings, and their derivatives. chebi_ontology chromenochromenes CHEBI:133135 chromenochromene CHEBI:133135 chromenochromenes ChEBI An organic anion that is the major structure of chlortetracycline at pH 7.3 (according to Marvin v 6.2.0.). -1 C22H22ClN2O8 InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31)/p-1/t7-,8-,15-,21-,22-/m0/s1 CYDMQBQPVICBEU-XRNKAMNCSA-M 477.872 477.10702 C1=CC(=C2C(=C1Cl)[C@@]([C@@]3(C(C2=O)=C([C@]4([C@@](C3)([C@@H](C(=C(C4=O)C(N)=O)[O-])[NH+](C)C)[H])O)O)[H])(C)O)[O-] MetaCyc:CPD-19258 (5S,5aS,6aS,7S,10aS)-9-carbamoyl-4-chloro-7-(dimethylazaniumyl)-5,10a,11-trihydroxy-5-methyl-10,12-dioxo-5,5a,6,6a,7,10,10a,12-octahydrotetracene-1,8-bis(olate) chebi_ontology 7-chlorotetracycline CHEBI:133598 chlortetracycline(1-) CHEBI:133598 (5S,5aS,6aS,7S,10aS)-9-carbamoyl-4-chloro-7-(dimethylazaniumyl)-5,10a,11-trihydroxy-5-methyl-10,12-dioxo-5,5a,6,6a,7,10,10a,12-octahydrotetracene-1,8-bis(olate) IUPAC 7-chlorotetracycline UniProt A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitroimidazol-1-yl)acetic acid with the aromatic amino group of benzylamine. Used for treatment of Chagas disease. 0 C12H12N4O3 InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17) CULUWZNBISUWAS-UHFFFAOYSA-N 260.249 260.09094 C1=C(C=CC=C1)CNC(CN2C(=NC=C2)[N+]([O-])=O)=O Beilstein:551486 CAS:22994-85-0 Drug_Central:322 KEGG:D02489 PMID:26760092 PMID:26760093 PMID:26760094 PMID:26760095 PMID:26974551 PMID:26982179 PMID:27001816 PMID:27067322 PMID:27158908 PMID:27161638 PMID:27223650 PMID:27246447 PMID:27376278 PMID:27487264 PMID:27488437 PMID:27550362 PMID:27619190 PMID:27688600 Reaxys:551486 Wikipedia:Benznidazole N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide chebi_ontology 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide N-Benzyl-2-nitroimidazol-1-yl-acetamide N-Benzyl-2-nitroimidazole-1-acetamide benznidazol benznidazole benznidazolum CHEBI:133833 benznidazole CHEBI:133833 Beilstein:551486 ChemIDplus CAS:22994-85-0 ChemIDplus CAS:22994-85-0 KEGG DRUG Drug_Central:322 DrugCentral PMID:26760092 Europe PMC PMID:26760093 Europe PMC PMID:26760094 Europe PMC PMID:26760095 Europe PMC PMID:26974551 Europe PMC PMID:26982179 Europe PMC PMID:27001816 Europe PMC PMID:27067322 Europe PMC PMID:27158908 Europe PMC PMID:27161638 Europe PMC PMID:27223650 Europe PMC PMID:27246447 Europe PMC PMID:27376278 Europe PMC PMID:27487264 Europe PMC PMID:27488437 Europe PMC PMID:27550362 Europe PMC PMID:27619190 Europe PMC PMID:27688600 Europe PMC Reaxys:551486 Reaxys N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide IUPAC 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide ChemIDplus N-Benzyl-2-nitroimidazol-1-yl-acetamide ChemIDplus N-Benzyl-2-nitroimidazole-1-acetamide ChemIDplus benznidazol ChemIDplus benznidazole ChemIDplus benznidazole KEGG_DRUG benznidazolum ChemIDplus Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa. Wikipedia:Volatile_organic_compound chebi_ontology VOC VOCs volatile organic compounds CHEBI:134179 volatile organic compound CHEBI:134179 VOC ChEBI VOCs ChEBI volatile organic compounds ChEBI 0 C15H24N4O6S2 InChI=1S/C15H24N4O6S2/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25)/t6-,7-,8+,9+,10-,11-/m1/s1 AVAACINZEOAHHE-VFZPANTDSA-N 420.507 420.11373 C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)CNS(N)(=O)=O)=C(N2C1=O)C(O)=O CAS:148016-81-3 Drug_Central:4149 HMDB:HMDB0041883 chebi_ontology doribax doripenem hydrate CHEBI:135928 doripenem CHEBI:135928 CAS:148016-81-3 DrugCentral Drug_Central:4149 DrugCentral doribax DrugCentral doripenem hydrate DrugCentral A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. glycols chebi_ontology Glykol CHEBI:13643 glycol CHEBI:13643 glycols IUPAC Glykol ChEBI Organonitrogen compounds that have the general structure R(1)(R(2))C=N(O)OH (R(1),R(2) = H, organyl). They are tautomers of C-nitro compounds. 0 CHNO2R2 59.024 59.00073 C(*)(=[N+](O)[O-])* chebi_ontology aci-nitro compounds oxime N-oxide oxime N-oxides CHEBI:136622 aci-nitro compound CHEBI:136622 aci-nitro compounds ChEBI oxime N-oxide ChEBI oxime N-oxides ChEBI Any inhibitor of S100 calcium-binding protein B. Wikipedia:S100B chebi_ontology S100 calcium-binding protein B inhibitors S100B inhibitor S100B inhibitors CHEBI:136651 S100 calcium-binding protein B inhibitor CHEBI:136651 S100 calcium-binding protein B inhibitors ChEBI S100B inhibitor ChEBI S100B inhibitors ChEBI A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent. PMID:26449612 chebi_ontology pro-agents proagent proagents CHEBI:136859 pro-agent CHEBI:136859 PMID:26449612 Europe PMC pro-agents ChEBI proagent ChEBI proagents ChEBI An organic cation obtained by protonation of any secondary amino compound; major species at pH 7.3. +1 H2NR2 16.023 16.01872 *[NH+](*)[H] MetaCyc:Secondary-Amines chebi_ontology a secondary amine secondary amine(1+) CHEBI:137419 secondary ammonium ion CHEBI:137419 a secondary amine UniProt secondary amine(1+) ChEBI An aminobenzoate that is the conjugate base of 4-aminosalicylic acid, obtained by deprotonation of the carboxy group. Major miscrospecies at pH 7.3. -1 C7H6NO3 InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)/p-1 WUBBRNOQWQTFEX-UHFFFAOYSA-M 152.128 152.03532 C1=C(N)C=C(O)C(C([O-])=O)=C1 MetaCyc:CPD-8817 PMID:23118010 Reaxys:3906055 chebi_ontology 4-aminosalicylate CHEBI:137598 4-aminosalicylate(1-) CHEBI:137598 PMID:23118010 SUBMITTER Reaxys:3906055 Reaxys 4-aminosalicylate UniProt An organic cation obtained by protonation of the amino group of any tertiary amino compound. +1 HNR3 15.015 15.01090 [NH+](*)(*)* chebi_ontology a tertiary amine tertiary amine(1+) tertiary ammonium ions CHEBI:137982 tertiary ammonium ion CHEBI:137982 a tertiary amine UniProt tertiary amine(1+) ChEBI tertiary ammonium ions ChEBI Any compound that can disrupt the functions of the endocrine (hormone) system PMID:27929035 PMID:28356401 PMID:28526231 Wikipedia:Endocrine_disruptor chebi_ontology endocrine disrupting chemical endocrine disrupting chemicals endocrine disrupting compound endocrine disrupting compounds endocrine disruptors endocrine-disrupting chemical endocrine-disrupting chemicals hormonally active agent hormonally active agents CHEBI:138015 endocrine disruptor CHEBI:138015 PMID:27929035 Europe PMC PMID:28356401 Europe PMC PMID:28526231 Europe PMC endocrine disrupting chemical ChEBI endocrine disrupting chemicals ChEBI endocrine disrupting compound ChEBI endocrine disrupting compounds ChEBI endocrine disruptors ChEBI endocrine-disrupting chemical ChEBI endocrine-disrupting chemicals ChEBI hormonally active agent ChEBI hormonally active agents ChEBI A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water. Wikipedia:Mineral_acid chebi_ontology inorganic acids mineral acid mineral acids CHEBI:138103 inorganic acid CHEBI:138103 inorganic acids ChEBI mineral acid ChEBI mineral acids ChEBI Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa). Wikipedia:https://en.wikipedia.org/wiki/Gas chebi_ontology gas molecular entities gaseous molecular entities gaseous molecular entity CHEBI:138675 gas molecular entity CHEBI:138675 gas molecular entities ChEBI gaseous molecular entities ChEBI gaseous molecular entity ChEBI A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. 0 C13H11NO5 InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17) KYGZCKSPAKDVKC-UHFFFAOYSA-N 261.23010 261.06372 CCn1cc(C(O)=O)c(=O)c2cc3OCOc3cc12 CHEBI:44731 CHEBI:7848 Beilstein:620635 CAS:14698-29-4 Drug_Central:2024 Gmelin:2609419 KEGG:C11342 KEGG:D02301 LINCS:LSM-5811 PDBeChem:OXI PMID:1245092 PMID:1650428 PMID:19596082 PMID:20151406 PMID:22670590 PMID:23353085 PMID:23773949 PMID:23816421 PMID:26678217 PMID:26920300 PMID:29438107 PMID:4616804 Patent:US3287458 Reaxys:620635 VSDB:1879 Wikipedia:Oxolinic_acid 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid chebi_ontology 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid 1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid OA acide oxolinique acido oxolinico acidum oxolinicum oxolinic acid CHEBI:138856 oxolinic acid CHEBI:138856 Beilstein:620635 Beilstein CAS:14698-29-4 ChemIDplus CAS:14698-29-4 KEGG COMPOUND Drug_Central:2024 DrugCentral Gmelin:2609419 Gmelin PMID:1245092 Europe PMC PMID:1650428 Europe PMC PMID:19596082 Europe PMC PMID:20151406 Europe PMC PMID:22670590 Europe PMC PMID:23353085 Europe PMC PMID:23773949 Europe PMC PMID:23816421 Europe PMC PMID:26678217 Europe PMC PMID:26920300 Europe PMC PMID:29438107 Europe PMC PMID:4616804 Europe PMC Reaxys:620635 Reaxys 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid IUPAC 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid ChemIDplus 1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid ChemIDplus 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid ChemIDplus OA KEGG_DRUG acide oxolinique ChemIDplus acido oxolinico WHO_MedNet acidum oxolinicum ChemIDplus oxolinic acid KEGG_DRUG oxolinic acid WHO_MedNet -1 CH2NO2 InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1 KXDHJXZQYSOELW-UHFFFAOYSA-M 60.03212 60.00910 NC([O-])=O Beilstein:3903503 CAS:302-11-4 Gmelin:239604 carbamate chebi_ontology Carbamat Karbamat carbamate ion carbamic acid, ion(1-) CHEBI:13941 carbamate CHEBI:13941 Beilstein:3903503 Beilstein CAS:302-11-4 ChemIDplus Gmelin:239604 Gmelin carbamate IUPAC carbamate UniProt Carbamat ChEBI Karbamat ChEBI carbamate ion ChemIDplus carbamic acid, ion(1-) ChemIDplus A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound. chebi_ontology sensitisers sensitizer sensitizers CHEBI:139492 sensitiser CHEBI:139492 sensitisers ChEBI sensitizer ChEBI sensitizers ChEBI An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9. Wikipedia:Enoyl-acyl_carrier_protein_reductase chebi_ontology EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors EC 1.3.1.9 inhibitor EC 1.3.1.9 inhibitors ENR inhibitor ENR inhibitors NADH-enoyl acyl carrier protein reductase inhibitor NADH-enoyl acyl carrier protein reductase inhibitors NADH-specific enoyl-ACP reductase inhibitor NADH-specific enoyl-ACP reductase inhibitors acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors enoyl-ACP reductase inhibitor enoyl-ACP reductase inhibitors enoyl-[acyl carrier protein] reductase inhibitor enoyl-[acyl carrier protein] reductase inhibitors CHEBI:139512 EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor CHEBI:139512 EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors ChEBI EC 1.3.1.9 inhibitor ChEBI EC 1.3.1.9 inhibitors ChEBI ENR inhibitor ChEBI ENR inhibitors ChEBI NADH-enoyl acyl carrier protein reductase inhibitor ChEBI NADH-enoyl acyl carrier protein reductase inhibitors ChEBI NADH-specific enoyl-ACP reductase inhibitor ChEBI NADH-specific enoyl-ACP reductase inhibitors ChEBI acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor ChEBI acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors ChEBI enoyl-ACP reductase inhibitor ChEBI enoyl-ACP reductase inhibitors ChEBI enoyl-[acyl carrier protein] reductase inhibitor ChEBI enoyl-[acyl carrier protein] reductase inhibitors ChEBI An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety. PMID:15326516 PMID:19908854 PMID:20382022 PMID:23295224 chebi_ontology alpha-hydroxy ketones alpha-hydroxy-ketone alpha-hydroxy-ketones alpha-hydroxyketone alpha-hydroxyketones CHEBI:139588 alpha-hydroxy ketone CHEBI:139588 PMID:15326516 Europe PMC PMID:19908854 Europe PMC PMID:20382022 Europe PMC PMID:23295224 Europe PMC alpha-hydroxy ketones ChEBI alpha-hydroxy-ketone ChEBI alpha-hydroxy-ketones ChEBI alpha-hydroxyketone ChEBI alpha-hydroxyketones ChEBI An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups. 0 C2HO2R3 57.028 56.99765 C(C(=O)*)(O)(*)* chebi_ontology tertiary alpha-hydroxy ketones tertiary alpha-hydroxy-ketone tertiary alpha-hydroxy-ketones tertiary alpha-hydroxyketone tertiary alpha-hydroxyketones CHEBI:139592 tertiary alpha-hydroxy ketone CHEBI:139592 tertiary alpha-hydroxy ketones ChEBI tertiary alpha-hydroxy-ketone ChEBI tertiary alpha-hydroxy-ketones ChEBI tertiary alpha-hydroxyketone ChEBI tertiary alpha-hydroxyketones ChEBI Any antimicrobial agent whose activity is dependent on the presence of calcium ions. PMID:18489906 PMID:22711659 PMID:29108098 PMID:29434326 chebi_ontology Ca(2+)-dependent antibiotic Ca(2+)-dependent antibiotics Ca-dependent antibiotic Ca-dependent antibiotics calcium-dependent antibiotic CHEBI:140190 calcium-dependent antibiotics CHEBI:140190 PMID:18489906 Europe PMC PMID:22711659 Europe PMC PMID:29108098 Europe PMC PMID:29434326 Europe PMC Ca(2+)-dependent antibiotic ChEBI Ca(2+)-dependent antibiotics ChEBI Ca-dependent antibiotic ChEBI Ca-dependent antibiotics ChEBI calcium-dependent antibiotic ChEBI A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1). 0 CHNOR2 43.025 43.00581 N(C(*)=O)(*)[H] chebi_ontology secondary carboxamides CHEBI:140325 secondary carboxamide CHEBI:140325 secondary carboxamides ChEBI A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2). 0 CNOR3 42.017 41.99799 N(C(*)=O)(*)* chebi_ontology tertiary carboxamides CHEBI:140326 tertiary carboxamide CHEBI:140326 tertiary carboxamides ChEBI Any polyunsaturated fatty acid carrying one or more hydroxy substituents. chebi_ontology CHEBI:140345 hydroxy polyunsaturated fatty acid CHEBI:140345 Any pathway inhibitor that inhibits the Hedgehog signalling pathway. Wikipedia:Hedgehog_pathway_inhibitors chebi_ontology Hedgehog pathway inhibitor Hedgehog pathway inhibitors Hedgehog signaling pathway inhibitors CHEBI:140921 Hedgehog signaling pathway inhibitor CHEBI:140921 Hedgehog pathway inhibitor ChEBI Hedgehog pathway inhibitors ChEBI Hedgehog signaling pathway inhibitors ChEBI An inhibitor of any of the glioma-associated oncogene (GLI) proteins. chebi_ontology GLI inhibitor GLI inhibitors glioma-associated oncogene inhibitors CHEBI:140922 glioma-associated oncogene inhibitor CHEBI:140922 GLI inhibitor ChEBI GLI inhibitors ChEBI glioma-associated oncogene inhibitors ChEBI A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex. Wikipedia:QoI chebi_ontology QOI QOIs Qo inhibitor Qo inhibitors quinone outside inhibitors CHEBI:141153 quinone outside inhibitor CHEBI:141153 QOI ChEBI QOIs ChEBI Qo inhibitor ChEBI Qo inhibitors ChEBI quinone outside inhibitors ChEBI An organic amino compound that is a hemiaminal in which the hydrogen atom of the hydroxy group has been replaced by an organyl group. General formula: R2C(OR')NR2 ( R =/= H ). Also known as alpha-amino ethers. 0 CNOR5 42.017 41.99799 N(C(O*)(*)*)(*)* chebi_ontology alpha-amino ether alpha-amino ethers hemiaminal ethers CHEBI:141498 hemiaminal ether CHEBI:141498 alpha-amino ether ChEBI alpha-amino ethers ChEBI hemiaminal ethers ChEBI A organic ion resulting from the deprotonation of the hydroxy group of any oxime. -1 CNO 42.017 41.99799 C(*)(=N[O-])* oxime anion chebi_ontology oximate oximates oxime anions CHEBI:142513 oxime anion CHEBI:142513 oxime anion ChEBI oximate ChEBI oximates ChEBI oxime anions ChEBI An ammonium ion that is the conjugate acid of tigecycline; major species at pH 7.3. +1 C29H40N5O8 InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/p+1/t12-,14-,21-,29-/m0/s1 FPZLLRFZJZRHSY-HJYUBDRYSA-O 586.658 586.28714 C1(C(=C([C@H]([C@@]2(C[C@@]3(CC4=C(C=C(C(=C4C(C3=C([C@]12O)O)=O)O)NC(C[NH2+]C(C)(C)C)=O)N(C)C)[H])[H])[NH+](C)C)[O-])C(=O)N)=O MetaCyc:CPD-19260 PMID:16128584 (1S,4aS,11aR,12aS)-8-[2-(tert-butylammonio)acetamido]-3-carbamoyl-10-(dimethylamino)-1-(dimethylammonio)-4a,5,7-trihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate chebi_ontology tigecycline CHEBI:142708 tigecycline(1+) CHEBI:142708 PMID:16128584 SUBMITTER (1S,4aS,11aR,12aS)-8-[2-(tert-butylammonio)acetamido]-3-carbamoyl-10-(dimethylamino)-1-(dimethylammonio)-4a,5,7-trihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate IUPAC tigecycline UniProt 0 C21H17N2O7R5 409.370 409.10358 C12=C(C=C(C(=C1C(C=3[C@]([C@@H]([C@]4([C@@H](C([O-])=C(C([C@@]4(O)C3O)=O)C(N)=O)[NH+](C)C)[H])*)(C2(*)*)[H])=O)O)*)* chebi_ontology a tetracycline CHEBI:144644 a tetracycline zwitterion CHEBI:144644 a tetracycline UniProt Macrolides (macrocyclic lactones) in which the macrocyclic ring contains more than one ester linkage. Macropolylides include macrodiolides, macrotriolides, macrotetrolides and macropentolides, each containing di-, tri-, tetra-, and penta- ester linkages, respectively, in one macrocyclic ring. Macrocyclic lactones containing nitrogen in their skeletons (azamacrolides and macrolide lactams) and also containing oxazole or thiazole in their skeletons are known in nature. chebi_ontology macropolylides CHEBI:145555 macropolylide CHEBI:145555 macropolylides ChEBI A macropolylide which contains two ester linkages in one macrocyclic ring. PMID:17446696 PMID:29624065 PMID:29671776 PMID:31247219 chebi_ontology macrodiolides CHEBI:145556 macrodiolide CHEBI:145556 PMID:17446696 Europe PMC PMID:29624065 Europe PMC PMID:29671776 Europe PMC PMID:31247219 Europe PMC macrodiolides ChEBI A macrolide in which the macrocyclic lactone ring includes an amide group. PMID:11678663 PMID:12227772 PMID:15248618 PMID:17378533 PMID:31226284 chebi_ontology macrolide lactams CHEBI:145565 macrolide lactam CHEBI:145565 PMID:11678663 Europe PMC PMID:12227772 Europe PMC PMID:15248618 Europe PMC PMID:17378533 Europe PMC PMID:31226284 Europe PMC macrolide lactams ChEBI A monocarboxylic acid anion that is the conjugate base of mupirocin obtained by the deprotonation of the carboxy group; major microspecies at pH 7.3. -1 C26H43O9 InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/p-1/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1 MINDHVHHQZYEEK-HBBNESRFSA-M 499.622 499.29126 [C@H]1([C@@H]([C@H](CO[C@H]1C\C(=C\C(OCCCCCCCCC([O-])=O)=O)\C)C[C@]2([C@](O2)([H])[C@@H](C)[C@H](C)O)[H])O)O 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoate chebi_ontology CHEBI:145790 mupirocin(1-) CHEBI:145790 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoate IUPAC A secondary ammonium ion derived from spectinomycin by protonation of the secondary amino group located between the two alcoholic hydroxy groups. +1 C14H25N2O7 InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/p+1/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1 UNFWWIHTNXNPBV-WXKVUWSESA-O 333.360 333.16563 [C@@H]12[C@H](O[C@@]3(O[C@H](C)CC([C@@]3(O1)O)=O)[H])[C@H]([C@H]([NH2+]C)[C@@H]([C@@H]2NC)O)O chebi_ontology spectinomycin CHEBI:146260 spectinomycin(1+) CHEBI:146260 spectinomycin UniProt Any organic heterotricyclic compound whose core skeleton consists of a benzodioxin ring that is ortho-fused to a pyran ring. chebi_ontology pyranobenzodioxins CHEBI:146295 pyranobenzodioxin CHEBI:146295 pyranobenzodioxins ChEBI Any agent that induces nausea and vomiting. chebi_ontology emetics CHEBI:149552 emetic CHEBI:149552 emetics ChEBI Any antiviral agent which inhibits the activity of coronaviruses. Wikipedia:Coronavirus anticoronaviral agent chebi_ontology anti-coronaviral agent anti-coronaviral agents anti-coronavirus agent anti-coronavirus agents anticoronaviral agents anticoronaviral drug anticoronaviral drugs anticoronavirus agent anticoronavirus agents anticoronviral agent anticoronviral agents CHEBI:149553 anticoronaviral agent CHEBI:149553 anticoronaviral agent ChEBI anti-coronaviral agent ChEBI anti-coronaviral agents ChEBI anti-coronavirus agent ChEBI anti-coronavirus agents ChEBI anticoronaviral agents ChEBI anticoronaviral drug ChEBI anticoronaviral drugs ChEBI anticoronavirus agent ChEBI anticoronavirus agents ChEBI anticoronviral agent ChEBI anticoronviral agents ChEBI Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms. 0 C29H39N5O8 InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1 FPZLLRFZJZRHSY-HJYUBDRYSA-N 585.64870 585.27986 [H][C@@]12Cc3c(cc(NC(=O)CNC(C)(C)C)c(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C CHEBI:29696 CHEBI:473970 CAS:220620-09-7 DrugBank:DB00560 Drug_Central:2661 KEGG:C12012 KEGG:D01079 PMID:17194827 PMID:17210772 PMID:17220399 PMID:17307973 PMID:17353238 PMID:17353249 Reaxys:8379453 (4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide chebi_ontology (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide CHEBI:149836 tigecycline CHEBI:149836 CAS:220620-09-7 ChemIDplus CAS:220620-09-7 KEGG COMPOUND Drug_Central:2661 DrugCentral PMID:17194827 ChEMBL PMID:17210772 ChEMBL PMID:17220399 ChEMBL PMID:17307973 ChEMBL PMID:17353238 ChEMBL PMID:17353249 ChEMBL Reaxys:8379453 Reaxys (4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide ChemIDplus A molecular entity that can transfer an electron to another molecular entity. electron donor chebi_ontology Elektronendonator donneur d'electron CHEBI:15022 electron donor CHEBI:15022 electron donor IUPAC Elektronendonator ChEBI donneur d'electron IUPAC A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide. -2 S InChI=1S/S/q-2 UCKMPCXJQFINFW-UHFFFAOYSA-N 32.06600 31.97317 [S--] CAS:18496-25-8 UM-BBD_compID:c0569 sulfanediide sulfide(2-) chebi_ontology S(2-) Sulfide sulphide CHEBI:15138 sulfide(2-) CHEBI:15138 CAS:18496-25-8 ChemIDplus UM-BBD_compID:c0569 UM-BBD sulfanediide IUPAC sulfide(2-) IUPAC S(2-) IUPAC Sulfide ChemIDplus sulphide ChEBI A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. CHEBI:13699 CHEBI:2377 KEGG:C00028 KEGG:C16722 Acceptor chebi_ontology A Akzeptor Hydrogen-acceptor Oxidized donor accepteur CHEBI:15339 acceptor CHEBI:15339 Acceptor KEGG_COMPOUND A KEGG_COMPOUND Akzeptor ChEBI Hydrogen-acceptor KEGG_COMPOUND Oxidized donor KEGG_COMPOUND accepteur ChEBI A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. +1 C5H14NO InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1 OEYIOHPDSNJKLS-UHFFFAOYSA-N 104.17080 104.10699 C[N+](C)(C)CCO CHEBI:13985 CHEBI:23212 CHEBI:3665 CHEBI:41524 Beilstein:1736748 CAS:62-49-7 DrugBank:DB00122 Drug_Central:3097 ECMDB:ECMDB00097 Gmelin:324597 HMDB:HMDB0000097 KEGG:C00114 KEGG:D07690 KNApSAcK:C00007298 MetaCyc:CHOLINE PDBeChem:CHT PMID:10930630 PMID:12826235 PMID:12946691 PMID:14972364 PMID:16210714 PMID:17087106 PMID:17283071 PMID:17344490 PMID:18204095 PMID:18230680 PMID:18786517 PMID:18786520 PMID:19246089 PMID:20038853 PMID:20446114 PMID:22770225 PMID:22961562 PMID:23095202 PMID:23616508 PMID:23637565 PMID:23733158 PMID:6420466 PMID:7590654 PMID:9517478 Reaxys:1736748 Wikipedia:Choline YMDB:YMDB00227 2-hydroxy-N,N,N-trimethylethanaminium Choline choline chebi_ontology Bilineurine CHOLINE ION N,N,N-trimethylethanol-ammonium N-trimethylethanolamine trimethylethanolamine CHEBI:15354 choline CHEBI:15354 Beilstein:1736748 Beilstein CAS:62-49-7 ChemIDplus CAS:62-49-7 KEGG COMPOUND Drug_Central:3097 DrugCentral Gmelin:324597 Gmelin PMID:10930630 Europe PMC PMID:12826235 Europe PMC PMID:12946691 Europe PMC PMID:14972364 Europe PMC PMID:16210714 Europe PMC PMID:17087106 Europe PMC PMID:17283071 Europe PMC PMID:17344490 Europe PMC PMID:18204095 Europe PMC PMID:18230680 Europe PMC PMID:18786517 Europe PMC PMID:18786520 Europe PMC PMID:19246089 Europe PMC PMID:20038853 Europe PMC PMID:20446114 Europe PMC PMID:22770225 Europe PMC PMID:22961562 Europe PMC PMID:23095202 Europe PMC PMID:23616508 Europe PMC PMID:23637565 Europe PMC PMID:23733158 Europe PMC PMID:6420466 Europe PMC PMID:7590654 Europe PMC PMID:9517478 Europe PMC Reaxys:1736748 Reaxys 2-hydroxy-N,N,N-trimethylethanaminium IUPAC Choline KEGG_COMPOUND choline UniProt Bilineurine KEGG_COMPOUND CHOLINE ION PDBeChem N,N,N-trimethylethanol-ammonium ChEBI N-trimethylethanolamine ChEBI trimethylethanolamine ChEBI A simple monocarboxylic acid containing two carbons. 0 C2H4O2 InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4) QTBSBXVTEAMEQO-UHFFFAOYSA-N 60.05200 60.02113 CC(O)=O CHEBI:22169 CHEBI:2387 CHEBI:40486 Beilstein:506007 CAS:64-19-7 Drug_Central:4211 Gmelin:1380 HMDB:HMDB0000042 KEGG:C00033 KEGG:D00010 KNApSAcK:C00001176 LIPID_MAPS_instance:LMFA01010002 MetaCyc:ACET PDBeChem:ACT PDBeChem:ACY PMID:12005138 PMID:15107950 PMID:16630552 PMID:16774200 PMID:17190852 PMID:19416101 PMID:19469536 PMID:22153255 PMID:22173419 PPDB:1333 Reaxys:506007 Wikipedia:Acetic_acid ACETIC ACID Acetic acid acetic acid chebi_ontology AcOH CH3-COOH CH3CO2H E 260 E-260 E260 Essigsaeure Ethanoic acid Ethylic acid HOAc INS No. 260 MeCO2H MeCOOH Methanecarboxylic acid acide acetique ethoic acid CHEBI:15366 acetic acid CHEBI:15366 Beilstein:506007 Beilstein CAS:64-19-7 ChemIDplus CAS:64-19-7 KEGG COMPOUND CAS:64-19-7 NIST Chemistry WebBook Drug_Central:4211 DrugCentral Gmelin:1380 Gmelin LIPID_MAPS_instance:LMFA01010002 LIPID MAPS PMID:12005138 Europe PMC PMID:15107950 Europe PMC PMID:16630552 Europe PMC PMID:16774200 Europe PMC PMID:17190852 Europe PMC PMID:19416101 Europe PMC PMID:19469536 Europe PMC PMID:22153255 Europe PMC PMID:22173419 Europe PMC Reaxys:506007 Reaxys ACETIC ACID PDBeChem Acetic acid KEGG_COMPOUND acetic acid IUPAC AcOH ChEBI CH3-COOH IUPAC CH3CO2H ChEBI E 260 ChEBI E-260 ChEBI E260 ChEBI Essigsaeure ChEBI Ethanoic acid KEGG_COMPOUND Ethylic acid ChemIDplus HOAc ChEBI INS No. 260 ChEBI MeCO2H ChEBI MeCOOH ChEBI Methanecarboxylic acid ChemIDplus acide acetique ChemIDplus ethoic acid ChEBI A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides. CHEBI:13723 CHEBI:22220 CHEBI:2445 CAS:1402-38-6 KEGG:C01775 Actinomycin chebi_ontology actinomycins CHEBI:15369 actinomycin CHEBI:15369 CAS:1402-38-6 ChemIDplus CAS:1402-38-6 KEGG COMPOUND Actinomycin KEGG_COMPOUND actinomycins ChEBI Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals. 0 C2H4O2(CH2O)n CHEBI:13755 CHEBI:22305 CHEBI:2561 KEGG:C01370 Wikipedia:Aldose Aldose chebi_ontology aldoses an aldose CHEBI:15693 aldose CHEBI:15693 Aldose KEGG_COMPOUND aldoses ChEBI an aldose UniProt Any alpha-amino acid having L-configuration at the alpha-carbon. 0 C2H4NO2R 74.05870 74.02420 N[C@@H]([*])C(O)=O CHEBI:13072 CHEBI:13243 CHEBI:13797 CHEBI:21224 CHEBI:6175 KEGG:C00151 L-alpha-amino acid L-alpha-amino acids chebi_ontology L-2-Amino acid L-Amino acid L-alpha-amino acids CHEBI:15705 L-alpha-amino acid CHEBI:15705 L-alpha-amino acid IUPAC L-alpha-amino acids IUPAC L-2-Amino acid KEGG_COMPOUND L-Amino acid KEGG_COMPOUND L-alpha-amino acids ChEBI A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. 0 CH3OR 31.034 31.01839 *C(O)([H])[H] CHEBI:13676 CHEBI:14887 CHEBI:26262 CHEBI:57489 CHEBI:8406 KEGG:C00226 Primary alcohol chebi_ontology 1-Alcohol a primary alcohol primary alcohols CHEBI:15734 primary alcohol CHEBI:15734 Primary alcohol KEGG_COMPOUND 1-Alcohol KEGG_COMPOUND a primary alcohol UniProt primary alcohols ChEBI A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects. -1 CHO2 InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1 BDAGIHXWWSANSR-UHFFFAOYSA-M 45.01744 44.99820 [H]C([O-])=O CHEBI:14276 CHEBI:24081 Beilstein:1901205 CAS:71-47-6 Gmelin:1006 HMDB:HMDB0000142 KEGG:C00058 MetaCyc:FORMATE PMID:17190852 PMID:3946945 Reaxys:1901205 UM-BBD_compID:c0106 Wikipedia:Formate formate chebi_ontology HCO2 anion aminate formiate formic acid, ion(1-) formylate hydrogen carboxylate methanoate CHEBI:15740 formate CHEBI:15740 Beilstein:1901205 Beilstein CAS:71-47-6 ChemIDplus CAS:71-47-6 NIST Chemistry WebBook Gmelin:1006 Gmelin PMID:17190852 Europe PMC PMID:3946945 Europe PMC Reaxys:1901205 Reaxys UM-BBD_compID:c0106 UM-BBD formate IUPAC formate UniProt HCO2 anion NIST_Chemistry_WebBook aminate ChEBI formiate ChEBI formic acid, ion(1-) ChemIDplus formylate ChEBI hydrogen carboxylate ChEBI methanoate ChEBI A peptide containing ten or more amino acid residues. C4H6N2O3R2(C2H2NOR)n CHEBI:14860 CHEBI:8314 KEGG:C00403 Polypeptide polypeptides chebi_ontology Polypeptid polipeptido CHEBI:15841 polypeptide CHEBI:15841 Polypeptide KEGG_COMPOUND polypeptides IUPAC Polypeptid ChEBI polipeptido ChEBI A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. 0 C6H5NO2 InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) PVNIIMVLHYAWGP-UHFFFAOYSA-N 123.10944 123.03203 OC(=O)c1cccnc1 CHEBI:25538 CHEBI:44319 CHEBI:7559 AGR:IND607088605 Beilstein:109591 CAS:59-67-6 Chemspider:913 DrugBank:DB00627 Drug_Central:2835 FooDB:FDB001014 Gmelin:3340 HMDB:HMDB0001488 KEGG:C00253 KEGG:D00049 KNApSAcK:C00000208 LINCS:LSM-4676 MetaCyc:NIACINE PDBeChem:NIO PMID:10540864 PMID:113218 PMID:12563315 PMID:12789870 PMID:135660 PMID:14550884 PMID:15037193 PMID:15183629 PMID:15205990 PMID:15311728 PMID:15627518 PMID:15651982 PMID:16018787 PMID:16172771 PMID:16322787 PMID:16400392 PMID:16449845 PMID:16767301 PMID:16877271 PMID:16945375 PMID:18037924 PMID:182198 PMID:186078 PMID:18993152 PMID:18996527 PMID:19369827 PMID:19592242 PMID:19678716 PMID:19779335 PMID:20979384 PMID:21632263 PMID:22116693 PMID:22155410 PMID:22229411 PMID:22366213 PMID:22458880 PMID:22770225 PMID:24029555 PMID:24568240 PMID:24675661 PMID:24848081 PMID:24975217 PMID:25040591 PMID:25241762 PMID:25429652 PMID:32954525 PMID:33273654 PMID:33932650 PMID:34066686 PMID:34085526 PMID:34117670 PMID:4033386 PMID:4259917 PMID:582105 PMID:699281 PMID:7217784 PMID:7581845 PMID:8306147 PMID:8423912 PMID:8679452 PMID:9107536 Reaxys:109591 Wikipedia:Niacin NICOTINIC ACID Nicotinic acid nicotinic acid pyridine-3-carboxylic acid chebi_ontology 3-Pyridylcarboxylic acid 3-carboxylpyridine 3-carboxypyridine 3-pyridinecarboxylic acid Niacin Niacor Niaspan Nicotinsaure Nikotinsaeure P.P. factor PP factor acide nicotinique acido nicotinico acidum nicotinicum anti-pellagra vitamin beta-pyridinecarboxylic acid m-pyridinecarboxylic acid nicotinic acid pellagra preventive factor pyridine-beta-carboxylic acid pyridine-carboxylique-3 vitamin B3 CHEBI:15940 nicotinic acid CHEBI:15940 AGR:IND607088605 Europe PMC Beilstein:109591 Beilstein CAS:59-67-6 ChemIDplus CAS:59-67-6 KEGG COMPOUND CAS:59-67-6 NIST Chemistry WebBook Drug_Central:2835 DrugCentral Gmelin:3340 Gmelin PMID:10540864 Europe PMC PMID:113218 Europe PMC PMID:12563315 Europe PMC PMID:12789870 Europe PMC PMID:135660 Europe PMC PMID:14550884 Europe PMC PMID:15037193 Europe PMC PMID:15183629 Europe PMC PMID:15205990 Europe PMC PMID:15311728 Europe PMC PMID:15627518 Europe PMC PMID:15651982 Europe PMC PMID:16018787 Europe PMC PMID:16172771 Europe PMC PMID:16322787 Europe PMC PMID:16400392 Europe PMC PMID:16449845 Europe PMC PMID:16767301 Europe PMC PMID:16877271 Europe PMC PMID:16945375 Europe PMC PMID:18037924 Europe PMC PMID:182198 Europe PMC PMID:186078 Europe PMC PMID:18993152 Europe PMC PMID:18996527 Europe PMC PMID:19369827 Europe PMC PMID:19592242 Europe PMC PMID:19678716 Europe PMC PMID:19779335 Europe PMC PMID:20979384 Europe PMC PMID:21632263 Europe PMC PMID:22116693 Europe PMC PMID:22155410 Europe PMC PMID:22229411 Europe PMC PMID:22366213 Europe PMC PMID:22458880 Europe PMC PMID:22770225 Europe PMC PMID:24029555 Europe PMC PMID:24568240 Europe PMC PMID:24675661 Europe PMC PMID:24848081 Europe PMC PMID:24975217 Europe PMC PMID:25040591 Europe PMC PMID:25241762 Europe PMC PMID:25429652 Europe PMC PMID:32954525 Europe PMC PMID:33273654 Europe PMC PMID:33932650 Europe PMC PMID:34066686 Europe PMC PMID:34085526 Europe PMC PMID:34117670 Europe PMC PMID:4033386 Europe PMC PMID:4259917 Europe PMC PMID:582105 Europe PMC PMID:699281 Europe PMC PMID:7217784 Europe PMC PMID:7581845 Europe PMC PMID:8306147 Europe PMC PMID:8423912 Europe PMC PMID:8679452 Europe PMC PMID:9107536 Europe PMC Reaxys:109591 Reaxys NICOTINIC ACID PDBeChem Nicotinic acid KEGG_COMPOUND nicotinic acid IUPAC pyridine-3-carboxylic acid IUPAC 3-Pyridylcarboxylic acid HMDB 3-carboxylpyridine ChemIDplus 3-carboxypyridine NIST_Chemistry_WebBook 3-pyridinecarboxylic acid KEGG_COMPOUND Niacin KEGG_COMPOUND Niacor KEGG_DRUG Niaspan KEGG_DRUG Nicotinsaure ChemIDplus Nikotinsaeure ChEBI P.P. factor NIST_Chemistry_WebBook PP factor NIST_Chemistry_WebBook acide nicotinique WHO_MedNet acido nicotinico WHO_MedNet acidum nicotinicum WHO_MedNet anti-pellagra vitamin NIST_Chemistry_WebBook beta-pyridinecarboxylic acid ChEBI m-pyridinecarboxylic acid NIST_Chemistry_WebBook nicotinic acid WHO_MedNet pellagra preventive factor NIST_Chemistry_WebBook pyridine-beta-carboxylic acid NIST_Chemistry_WebBook pyridine-carboxylique-3 ChemIDplus vitamin B3 ChEBI A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues. 0 (C5H8O6PR)n.C10H17O10PR2 CHEBI:13672 CHEBI:14859 CHEBI:8312 KEGG:C00419 Polynucleotide chebi_ontology polynucleotides CHEBI:15986 polynucleotide CHEBI:15986 Polynucleotide KEGG_COMPOUND polynucleotides ChEBI An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4. 0 C4H5N3O InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8) OPTASPLRGRRNAP-UHFFFAOYSA-N 111.10212 111.04326 Nc1cc[nH]c(=O)n1 CHEBI:14066 CHEBI:23531 CHEBI:4072 CHEBI:41732 Beilstein:2637 CAS:71-30-7 Gmelin:82472 HMDB:HMDB0000630 KEGG:C00380 KNApSAcK:C00001498 MetaCyc:CYTOSINE PDBeChem:CYT PMID:14253484 PMID:22770225 PMID:7877593 Reaxys:2637 Wikipedia:Cytosine 4-aminopyrimidin-2(1H)-one Cytosine cytosine chebi_ontology 4-amino-2(1H)-pyrimidinone 4-amino-2-hydroxypyrimidine C Cyt Cytosin Zytosin CHEBI:16040 cytosine CHEBI:16040 4-aminopyrimidin-2(1H)-one IUPAC Cytosine KEGG_COMPOUND cytosine UniProt 4-amino-2(1H)-pyrimidinone NIST_Chemistry_WebBook 4-amino-2-hydroxypyrimidine NIST_Chemistry_WebBook C ChEBI Cyt CBN Cytosin ChEBI Zytosin ChEBI Beilstein:2637 Beilstein CAS:71-30-7 ChemIDplus CAS:71-30-7 KEGG COMPOUND CAS:71-30-7 NIST Chemistry WebBook Gmelin:82472 Gmelin PMID:14253484 Europe PMC PMID:22770225 Europe PMC PMID:7877593 Europe PMC Reaxys:2637 Reaxys A monoatomic monoanion resulting from the addition of an electron to any halogen atom. -1 X 0.0 0.0 [*-] CHEBI:14384 CHEBI:5605 KEGG:C00462 halide ions chebi_ontology HX Halide a halide anion halide anions halide(1-) halides halogen anion CHEBI:16042 halide anion CHEBI:16042 halide ions IUPAC HX KEGG_COMPOUND Halide KEGG_COMPOUND a halide anion UniProt halide anions ChEBI halide(1-) ChEBI halides ChEBI halogen anion ChEBI An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. 0 H3N InChI=1S/H3N/h1H3 QGZKDVFQNNGYKY-UHFFFAOYSA-N 17.03056 17.02655 [H]N([H])[H] CHEBI:13405 CHEBI:13406 CHEBI:13407 CHEBI:13771 CHEBI:22533 CHEBI:44269 CHEBI:44284 CHEBI:44404 CHEBI:7434 Beilstein:3587154 CAS:7664-41-7 Drug_Central:4625 Gmelin:79 HMDB:HMDB0000051 KEGG:C00014 KEGG:D02916 KNApSAcK:C00007267 MetaCyc:AMMONIA MolBase:930 PDBeChem:NH3 PMID:110589 PMID:11139349 PMID:11540049 PMID:11746427 PMID:11783653 PMID:13753780 PMID:14663195 PMID:15092448 PMID:15094021 PMID:15554424 PMID:15969015 PMID:16008360 PMID:16050680 PMID:16348008 PMID:16349403 PMID:16614889 PMID:16664306 PMID:16842901 PMID:17025297 PMID:17439666 PMID:17569513 PMID:17737668 PMID:18670398 PMID:22002069 PMID:22081570 PMID:22088435 PMID:22100291 PMID:22130175 PMID:22150211 PMID:22240068 PMID:22290316 PMID:22342082 PMID:22385337 PMID:22443779 PMID:22560242 Reaxys:3587154 Wikipedia:Ammonia AMMONIA Ammonia ammonia azane chebi_ontology Ammoniak NH3 R-717 [NH3] ammoniac amoniaco spirit of hartshorn CHEBI:16134 ammonia CHEBI:16134 Beilstein:3587154 Beilstein CAS:7664-41-7 ChemIDplus CAS:7664-41-7 KEGG COMPOUND CAS:7664-41-7 NIST Chemistry WebBook Drug_Central:4625 DrugCentral Gmelin:79 Gmelin PMID:110589 Europe PMC PMID:11139349 Europe PMC PMID:11540049 Europe PMC PMID:11746427 Europe PMC PMID:11783653 Europe PMC PMID:13753780 Europe PMC PMID:14663195 Europe PMC PMID:15092448 Europe PMC PMID:15094021 Europe PMC PMID:15554424 Europe PMC PMID:15969015 Europe PMC PMID:16008360 Europe PMC PMID:16050680 Europe PMC PMID:16348008 Europe PMC PMID:16349403 Europe PMC PMID:16614889 Europe PMC PMID:16664306 Europe PMC PMID:16842901 Europe PMC PMID:17025297 Europe PMC PMID:17439666 Europe PMC PMID:17569513 Europe PMC PMID:17737668 Europe PMC PMID:18670398 Europe PMC PMID:22002069 Europe PMC PMID:22081570 Europe PMC PMID:22088435 Europe PMC PMID:22100291 Europe PMC PMID:22130175 Europe PMC PMID:22150211 Europe PMC PMID:22240068 Europe PMC PMID:22290316 Europe PMC PMID:22342082 Europe PMC PMID:22385337 Europe PMC PMID:22443779 Europe PMC PMID:22560242 Europe PMC Reaxys:3587154 Reaxys AMMONIA PDBeChem Ammonia KEGG_COMPOUND ammonia IUPAC azane IUPAC Ammoniak ChemIDplus NH3 IUPAC NH3 KEGG_COMPOUND NH3 UniProt R-717 ChEBI [NH3] MolBase ammoniac ChEBI amoniaco ChEBI spirit of hartshorn ChemIDplus A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen. 0 H2S InChI=1S/H2S/h1H2 RWSOTUBLDIXVET-UHFFFAOYSA-N 34.08188 33.98772 [H]S[H] CHEBI:13356 CHEBI:14414 CHEBI:24639 CHEBI:43058 CHEBI:45489 CHEBI:5787 Beilstein:3535004 CAS:7783-06-4 Drug_Central:4260 Gmelin:303 KEGG:C00283 KNApSAcK:C00007266 MolBase:1709 PDBeChem:H2S PMID:11788560 PMID:14654297 PMID:15003943 PMID:15607739 PMID:16446402 PMID:18098324 PMID:18524810 PMID:18948540 PMID:19695225 PMID:22004989 PMID:22378060 PMID:22448627 PMID:22473176 PMID:22486842 PMID:22520971 PMID:22787557 UM-BBD_compID:c0239 Wikipedia:Hydrogen_sulfide Hydrogen sulfide dihydridosulfur dihydrogen(sulfide) hydrogen sulfide sulfane chebi_ontology H2S HYDROSULFURIC ACID Hydrogen-sulfide Schwefelwasserstoff Sulfide [SH2] acide sulfhydrique dihydrogen monosulfide dihydrogen sulfide hydrogen monosulfide hydrogen sulphide hydrogene sulfure sulfure d'hydrogene CHEBI:16136 hydrogen sulfide CHEBI:16136 Beilstein:3535004 Beilstein CAS:7783-06-4 ChemIDplus CAS:7783-06-4 KEGG COMPOUND CAS:7783-06-4 NIST Chemistry WebBook Drug_Central:4260 DrugCentral Gmelin:303 Gmelin PMID:11788560 Europe PMC PMID:14654297 Europe PMC PMID:15003943 Europe PMC PMID:15607739 Europe PMC PMID:16446402 Europe PMC PMID:18098324 Europe PMC PMID:18524810 Europe PMC PMID:18948540 Europe PMC PMID:19695225 Europe PMC PMID:22004989 Europe PMC PMID:22378060 Europe PMC PMID:22448627 Europe PMC PMID:22473176 Europe PMC PMID:22486842 Europe PMC PMID:22520971 Europe PMC PMID:22787557 Europe PMC UM-BBD_compID:c0239 UM-BBD Hydrogen sulfide KEGG_COMPOUND dihydridosulfur IUPAC dihydrogen(sulfide) IUPAC hydrogen sulfide IUPAC sulfane IUPAC H2S IUPAC H2S KEGG_COMPOUND HYDROSULFURIC ACID PDBeChem Hydrogen-sulfide KEGG_COMPOUND Schwefelwasserstoff ChemIDplus Sulfide KEGG_COMPOUND [SH2] MolBase acide sulfhydrique ChemIDplus dihydrogen monosulfide NIST_Chemistry_WebBook dihydrogen sulfide NIST_Chemistry_WebBook hydrogen monosulfide NIST_Chemistry_WebBook hydrogen sulphide ChemIDplus hydrogene sulfure ChemIDplus sulfure d'hydrogene ChEBI The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1. -1 C7H5O2 InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)/p-1 WPYMKLBDIGXBTP-UHFFFAOYSA-M 121.11340 121.02950 [O-]C(=O)c1ccccc1 CHEBI:13879 CHEBI:22717 Beilstein:1862486 CAS:766-76-7 Gmelin:2945 HMDB:HMDB0001870 KEGG:C00180 MetaCyc:BENZOATE Reaxys:1862486 UM-BBD_compID:c0121 benzoate chebi_ontology Benzenecarboxylate Benzeneformate Benzenemethanoate Phenylcarboxylate Phenylformate benzoate anion benzoic acid, ion(1-) CHEBI:16150 benzoate CHEBI:16150 Beilstein:1862486 Beilstein CAS:766-76-7 ChemIDplus CAS:766-76-7 NIST Chemistry WebBook Gmelin:2945 Gmelin Reaxys:1862486 Reaxys UM-BBD_compID:c0121 UM-BBD benzoate IUPAC benzoate UniProt Benzenecarboxylate HMDB Benzeneformate HMDB Benzenemethanoate HMDB Phenylcarboxylate HMDB Phenylformate HMDB benzoate anion NIST_Chemistry_WebBook benzoic acid, ion(1-) ChemIDplus A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. 0 C13H17N5O8S2 InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 435.43300 435.05185 C[C@H]1[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\c2csc([NH3+])n2)C(=O)N1S([O-])(=O)=O CHEBI:2960 CHEBI:41008 Beilstein:3577211 CAS:78110-38-0 DrugBank:DB00355 Drug_Central:279 KEGG:C06840 KEGG:D00240 PDBeChem:AZR PMID:1384868 PMID:15123864 PMID:24119095 PMID:24176390 PMID:24369293 PMID:25049240 PMID:25091537 PMID:25295210 PMID:28543395 PMID:29017833 Patent:NL8100571 Reaxys:3577211 Wikipedia:Aztreonam (2S,3S)-3-{(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(2-carboxypropan-2-yloxy)imino]acetamido}-2-methyl-4-oxoazetidine-1-sulfonate chebi_ontology (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid AZT Azactam Primbactam aztreonam aztreonamum CHEBI:161680 aztreonam CHEBI:161680 Beilstein:3577211 Beilstein CAS:78110-38-0 ChemIDplus Drug_Central:279 DrugCentral PMID:1384868 Europe PMC PMID:15123864 Europe PMC PMID:24119095 Europe PMC PMID:24176390 Europe PMC PMID:24369293 Europe PMC PMID:25049240 Europe PMC PMID:25091537 Europe PMC PMID:25295210 Europe PMC PMID:28543395 Europe PMC PMID:29017833 Europe PMC Reaxys:3577211 Reaxys (2S,3S)-3-{(2Z)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(2-carboxypropan-2-yloxy)imino]acetamido}-2-methyl-4-oxoazetidine-1-sulfonate IUPAC (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid ChemIDplus AZT ChEBI Azactam DrugBank Primbactam DrugBank aztreonam ChEBI aztreonamum ChemIDplus A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid. -2 O4S InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2 QAOWNCQODCNURD-UHFFFAOYSA-L 96.06360 95.95283 [O-]S([O-])(=O)=O CHEBI:15135 CHEBI:45687 CHEBI:9335 Beilstein:3648446 CAS:14808-79-8 Gmelin:2120 HMDB:HMDB0001448 KEGG:C00059 KEGG:D05963 MetaCyc:SULFATE PDBeChem:SO4 PMID:11200094 PMID:11452993 PMID:11581495 PMID:11798107 PMID:12166931 PMID:12668033 PMID:14597181 PMID:15093386 PMID:15984785 PMID:16186560 PMID:16345535 PMID:16347366 PMID:16348007 PMID:16483812 PMID:16534979 PMID:16656509 PMID:16742508 PMID:16742518 PMID:17120760 PMID:17420092 PMID:17439666 PMID:17709180 PMID:18398178 PMID:18815700 PMID:18846414 PMID:19047345 PMID:19244483 PMID:19544990 PMID:19628332 PMID:19812358 PMID:30398859 Reaxys:3648446 Wikipedia:Sulfate Sulfate sulfate tetraoxidosulfate(2-) tetraoxosulfate(2-) tetraoxosulfate(VI) chebi_ontology SO4(2-) SULFATE ION Sulfate anion(2-) Sulfate dianion Sulfate(2-) Sulfuric acid ion(2-) [SO4](2-) sulphate sulphate ion CHEBI:16189 sulfate CHEBI:16189 Beilstein:3648446 Beilstein CAS:14808-79-8 ChemIDplus CAS:14808-79-8 NIST Chemistry WebBook Gmelin:2120 Gmelin PMID:11200094 Europe PMC PMID:11452993 Europe PMC PMID:11581495 Europe PMC PMID:11798107 Europe PMC PMID:12166931 Europe PMC PMID:12668033 Europe PMC PMID:14597181 Europe PMC PMID:15093386 Europe PMC PMID:15984785 Europe PMC PMID:16186560 Europe PMC PMID:16345535 Europe PMC PMID:16347366 Europe PMC PMID:16348007 Europe PMC PMID:16483812 Europe PMC PMID:16534979 Europe PMC PMID:16656509 Europe PMC PMID:16742508 Europe PMC PMID:16742518 Europe PMC PMID:17120760 Europe PMC PMID:17420092 Europe PMC PMID:17439666 Europe PMC PMID:17709180 Europe PMC PMID:18398178 Europe PMC PMID:18815700 Europe PMC PMID:18846414 Europe PMC PMID:19047345 Europe PMC PMID:19244483 Europe PMC PMID:19544990 Europe PMC PMID:19628332 Europe PMC PMID:19812358 Europe PMC PMID:30398859 Europe PMC Reaxys:3648446 Reaxys Sulfate KEGG_COMPOUND sulfate IUPAC sulfate UniProt tetraoxidosulfate(2-) IUPAC tetraoxosulfate(2-) IUPAC tetraoxosulfate(VI) IUPAC SO4(2-) IUPAC SULFATE ION PDBeChem Sulfate anion(2-) HMDB Sulfate dianion HMDB Sulfate(2-) HMDB Sulfuric acid ion(2-) HMDB [SO4](2-) IUPAC sulphate ChEBI sulphate ion ChEBI A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). 0 CH4N2O InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4) XSQUKJJJFZCRTK-UHFFFAOYSA-N 60.05534 60.03236 NC(N)=O CHEBI:15292 CHEBI:27218 CHEBI:46379 CHEBI:9888 Beilstein:635724 CAS:57-13-6 DrugBank:DB03904 Drug_Central:4264 ECMDB:ECMDB04172 Gmelin:1378 HMDB:HMDB0000294 KEGG:C00086 KEGG:D00023 KNApSAcK:C00007314 MetaCyc:UREA PDBeChem:URE PMID:18037357 PMID:22770225 PPDB:1728 Reaxys:635724 UM-BBD_compID:c0165 Wikipedia:Urea YMDB:YMDB00003 UREA Urea urea chebi_ontology 1728 Carbamide E927b H2NC(O)NH2 Harnstoff Karbamid carbamide carbonyldiamide ur uree CHEBI:16199 urea CHEBI:16199 Beilstein:635724 Beilstein CAS:57-13-6 ChemIDplus CAS:57-13-6 KEGG COMPOUND CAS:57-13-6 NIST Chemistry WebBook Drug_Central:4264 DrugCentral Gmelin:1378 Gmelin PMID:18037357 Europe PMC PMID:22770225 Europe PMC Reaxys:635724 Reaxys UM-BBD_compID:c0165 UM-BBD UREA PDBeChem Urea KEGG_COMPOUND urea IUPAC urea UniProt 1728 PPDB Carbamide KEGG_COMPOUND E927b ChEBI H2NC(O)NH2 ChEBI Harnstoff NIST_Chemistry_WebBook Karbamid ChEBI carbamide ChEBI carbonyldiamide NIST_Chemistry_WebBook ur IUPAC uree ChEBI A divalent inorganic anion obtained by removal of both protons from phosphonic acid -2 HO3P InChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)/p-2 ABLZXFCXXLZCGV-UHFFFAOYSA-L 79.97990 79.96743 [H]P([O-])([O-])=O CHEBI:14820 CHEBI:39856 CHEBI:8154 Gmelin:1618 KEGG:C06701 MetaCyc:PHOSPHONATE PDBeChem:2PO hydridotrioxidophosphate(2-) hydridotrioxophosphate(2-) chebi_ontology PHO3(2-) PHOSPHONATE Phosphonate [PHO3](2-) phosphonate CHEBI:16215 phosphonate(2-) CHEBI:16215 Gmelin:1618 Gmelin hydridotrioxidophosphate(2-) IUPAC hydridotrioxophosphate(2-) IUPAC PHO3(2-) IUPAC PHOSPHONATE PDBeChem Phosphonate KEGG_COMPOUND [PHO3](2-) IUPAC phosphonate IUPAC phosphonate UniProt An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond. 0 H2O2 InChI=1S/H2O2/c1-2/h1-2H MHAJPDPJQMAIIY-UHFFFAOYSA-N 34.01468 34.00548 [H]OO[H] CHEBI:13354 CHEBI:13355 CHEBI:24637 CHEBI:44812 CHEBI:5586 Beilstein:3587191 CAS:7722-84-1 Drug_Central:3281 Gmelin:509 HMDB:HMDB0003125 KEGG:C00027 KEGG:D00008 MetaCyc:HYDROGEN-PEROXIDE MolBase:932 PDBeChem:PEO PMID:10455187 PMID:10557015 PMID:10849784 PMID:11033421 PMID:11105916 PMID:11318558 PMID:11387393 PMID:11809417 PMID:11864786 PMID:11893576 PMID:12867293 PMID:12934880 PMID:14679422 PMID:15028418 PMID:15133946 PMID:15298493 PMID:16337875 PMID:16463018 PMID:16864869 PMID:17020896 PMID:17179007 PMID:17610934 PMID:17948137 PMID:18179203 PMID:18182702 PMID:18306736 PMID:18443210 PMID:18592736 PMID:19107210 PMID:19229032 PMID:19297450 PMID:19509065 PMID:26352695 PMID:26365231 PMID:7548021 PMID:7581816 PMID:8048546 PMID:8375042 PMID:8451754 PMID:9051670 PMID:9100841 PMID:9168257 PMID:9202721 PMID:9558114 PPDB:387 Reaxys:3587191 Wikipedia:Hydrogen_peroxide HYDROGEN PEROXIDE Hydrogen peroxide bis(hydridooxygen)(O--O) dihydrogen peroxide dihydrogen(peroxide) dioxidane hydrogen peroxide chebi_ontology H2O2 HOOH Oxydol [OH(OH)] dihydrogen dioxide perhydrol CHEBI:16240 hydrogen peroxide CHEBI:16240 Beilstein:3587191 Beilstein CAS:7722-84-1 ChemIDplus CAS:7722-84-1 KEGG COMPOUND CAS:7722-84-1 NIST Chemistry WebBook Drug_Central:3281 DrugCentral Gmelin:509 Gmelin PMID:10455187 Europe PMC PMID:10557015 Europe PMC PMID:10849784 Europe PMC PMID:11033421 Europe PMC PMID:11105916 Europe PMC PMID:11318558 Europe PMC PMID:11387393 Europe PMC PMID:11809417 Europe PMC PMID:11864786 Europe PMC PMID:11893576 Europe PMC PMID:12867293 Europe PMC PMID:12934880 Europe PMC PMID:14679422 Europe PMC PMID:15028418 Europe PMC PMID:15133946 Europe PMC PMID:15298493 Europe PMC PMID:16337875 Europe PMC PMID:16463018 Europe PMC PMID:16864869 Europe PMC PMID:17020896 Europe PMC PMID:17179007 Europe PMC PMID:17610934 Europe PMC PMID:17948137 Europe PMC PMID:18179203 Europe PMC PMID:18182702 Europe PMC PMID:18306736 Europe PMC PMID:18443210 Europe PMC PMID:18592736 Europe PMC PMID:19107210 Europe PMC PMID:19229032 Europe PMC PMID:19297450 Europe PMC PMID:19509065 Europe PMC PMID:26352695 Europe PMC PMID:26365231 Europe PMC PMID:7548021 Europe PMC PMID:7581816 Europe PMC PMID:8048546 Europe PMC PMID:8375042 Europe PMC PMID:8451754 Europe PMC PMID:9051670 Europe PMC PMID:9100841 Europe PMC PMID:9168257 Europe PMC PMID:9202721 Europe PMC PMID:9558114 Europe PMC Reaxys:3587191 Reaxys HYDROGEN PEROXIDE PDBeChem Hydrogen peroxide KEGG_COMPOUND bis(hydridooxygen)(O--O) IUPAC dihydrogen peroxide IUPAC dihydrogen(peroxide) IUPAC dioxidane IUPAC hydrogen peroxide IUPAC H2O2 KEGG_COMPOUND H2O2 UniProt HOOH IUPAC Oxydol KEGG_COMPOUND [OH(OH)] MolBase dihydrogen dioxide IUPAC perhydrol MetaCyc A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides. CHEBI:14816 CHEBI:26063 CHEBI:8150 KEGG:C00865 Phospholipid chebi_ontology a phospholipid derivative phospholipids CHEBI:16247 phospholipid CHEBI:16247 Phospholipid KEGG_COMPOUND a phospholipid derivative UniProt phospholipids ChEBI The D-enantiomer of proline. 0 C5H9NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 ONIBWKKTOPOVIA-SCSAIBSYSA-N 115.13050 115.06333 OC(=O)[C@H]1CCCN1 CHEBI:13008 CHEBI:21070 CHEBI:42012 CHEBI:42129 CHEBI:42213 CHEBI:4226 CHEBI:45156 Beilstein:80811 CAS:344-25-2 DrugBank:DB02853 Gmelin:833984 HMDB:HMDB0003411 KEGG:C00763 MetaCyc:D-PROLINE PDBeChem:DPR PMID:19023642 PMID:20023020 PMID:20959625 PMID:21374575 PMID:21563681 PMID:22475019 PMID:22479580 Reaxys:80811 Wikipedia:D-proline D-PROLINE D-Proline D-proline chebi_ontology (2R)-pyrrolidine-2-carboxylic acid (R)-2-Carboxypyrrolidine (R)-pyrrolidine-2-carboxylic acid D-Prolin DPR CHEBI:16313 D-proline CHEBI:16313 Beilstein:80811 Beilstein CAS:344-25-2 ChemIDplus CAS:344-25-2 KEGG COMPOUND Gmelin:833984 Gmelin PMID:19023642 Europe PMC PMID:20023020 Europe PMC PMID:20959625 Europe PMC PMID:21374575 Europe PMC PMID:21563681 Europe PMC PMID:22475019 Europe PMC PMID:22479580 Europe PMC Reaxys:80811 Reaxys D-PROLINE PDBeChem D-Proline KEGG_COMPOUND D-proline IUPAC (2R)-pyrrolidine-2-carboxylic acid IUPAC (R)-2-Carboxypyrrolidine HMDB (R)-pyrrolidine-2-carboxylic acid ChEBI D-Prolin ChEBI DPR PDBeChem Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers. 0 SR2 32.066 31.97207 CHEBI:13694 CHEBI:26960 CHEBI:9340 KEGG:C00297 sulfides chebi_ontology RSR Sulfide Thioether organic sulfides thioethers CHEBI:16385 organic sulfide CHEBI:16385 sulfides IUPAC RSR IUPAC Sulfide KEGG_COMPOUND Thioether KEGG_COMPOUND organic sulfides ChEBI thioethers IUPAC An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. 0 C12H7Cl3O2 InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H XEFQLINVKFYRCS-UHFFFAOYSA-N 289.54200 287.95116 Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl CHEBI:29697 CHEBI:47700 Beilstein:2057142 CAS:3380-34-5 DrugBank:DB08604 Drug_Central:3631 KEGG:C12059 KEGG:D06226 LINCS:LSM-2929 PDBeChem:TCL PMID:11175846 PMID:11418506 PMID:15269185 PMID:17567585 PMID:18837732 PMID:18937596 PMID:19388793 PMID:21094257 PMID:21166831 PMID:21833630 PMID:22105314 PMID:22561896 PMID:22746545 PMID:23146048 PMID:23161706 PMID:23192912 PMID:23282071 PMID:23313217 PMID:23320506 PMID:23368947 PMID:23435526 PMID:23561013 PMID:23592331 PMID:23614034 PMID:23648333 PMID:23791346 PMID:23831729 PMID:23890965 PMID:23927454 PMID:24079913 PMID:25179274 PMID:28236114 PMID:28339349 PMID:28632490 PMID:28741979 PMID:29030459 PMID:29067681 PMID:29100157 PMID:29109308 PMID:29111213 PMID:29111444 PMID:29131715 PMID:29150338 PMID:29154092 PMID:29172042 PMID:29175687 PMID:29197580 PMID:29205483 PMID:29214481 PMID:29232866 PMID:29277667 PMID:29332277 PMID:29340711 PMID:29348637 Patent:NL6401526 Patent:US3506720 Patent:US3629477 Reaxys:2057142 Wikipedia:Triclosan 5-chloro-2-(2,4-dichlorophenoxy)phenol Triclosan chebi_ontology 2,4,4'-Trichloro-2'-hydroxydiphenyl ether 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol triclosan triclosanum CHEBI:164200 triclosan CHEBI:164200 Beilstein:2057142 Beilstein CAS:3380-34-5 ChemIDplus CAS:3380-34-5 KEGG COMPOUND Drug_Central:3631 DrugCentral PMID:11175846 Europe PMC PMID:11418506 Europe PMC PMID:15269185 Europe PMC PMID:17567585 Europe PMC PMID:18837732 Europe PMC PMID:18937596 Europe PMC PMID:19388793 Europe PMC PMID:21094257 Europe PMC PMID:21166831 Europe PMC PMID:21833630 Europe PMC PMID:22105314 Europe PMC PMID:22561896 Europe PMC PMID:22746545 Europe PMC PMID:23146048 Europe PMC PMID:23161706 Europe PMC PMID:23192912 Europe PMC PMID:23282071 Europe PMC PMID:23313217 Europe PMC PMID:23320506 Europe PMC PMID:23368947 Europe PMC PMID:23435526 Europe PMC PMID:23561013 Europe PMC PMID:23592331 Europe PMC PMID:23614034 Europe PMC PMID:23648333 Europe PMC PMID:23791346 Europe PMC PMID:23831729 Europe PMC PMID:23890965 Europe PMC PMID:23927454 Europe PMC PMID:24079913 Europe PMC PMID:25179274 Europe PMC PMID:28236114 Europe PMC PMID:28339349 Europe PMC PMID:28632490 Europe PMC PMID:28741979 Europe PMC PMID:29030459 Europe PMC PMID:29067681 Europe PMC PMID:29100157 Europe PMC PMID:29109308 Europe PMC PMID:29111213 Europe PMC PMID:29111444 Europe PMC PMID:29131715 Europe PMC PMID:29150338 Europe PMC PMID:29154092 Europe PMC PMID:29172042 Europe PMC PMID:29175687 Europe PMC PMID:29197580 Europe PMC PMID:29205483 Europe PMC PMID:29214481 Europe PMC PMID:29232866 Europe PMC PMID:29277667 Europe PMC PMID:29332277 Europe PMC PMID:29340711 Europe PMC PMID:29348637 Europe PMC Reaxys:2057142 Reaxys 5-chloro-2-(2,4-dichlorophenoxy)phenol IUPAC Triclosan KEGG_COMPOUND 2,4,4'-Trichloro-2'-hydroxydiphenyl ether ChemIDplus 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol ChEMBL triclosan ChemIDplus triclosan WHO_MedNet triclosanum ChemIDplus A naturally occurring polypeptide synthesized at the ribosome. CHEBI:8526 KEGG:C00017 chebi_ontology Protein a protein polypeptide chain protein polypeptide chains CHEBI:16541 protein polypeptide chain CHEBI:16541 Protein KEGG_COMPOUND a protein UniProt polypeptide chain ChEBI protein polypeptide chains ChEBI Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates. CHEBI:15131 CHEBI:23008 CHEBI:9318 Wikipedia:Carbohydrate carbohydrate carbohydrates chebi_ontology Kohlenhydrat Kohlenhydrate a carbohydrate carbohidrato carbohidratos glucide glucides glucido glucidos hydrates de carbone saccharide saccharides saccharidum CHEBI:16646 carbohydrate CHEBI:16646 carbohydrate IUPAC carbohydrates IUPAC Kohlenhydrat ChEBI Kohlenhydrate ChEBI a carbohydrate UniProt carbohidrato IUPAC carbohidratos IUPAC glucide ChEBI glucides ChEBI glucido ChEBI glucidos ChEBI hydrates de carbone ChEBI saccharide IUPAC saccharides IUPAC saccharidum ChEBI Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. 0 (C2H2NOR)nC2H3NOR CHEBI:14753 CHEBI:25906 CHEBI:7990 KEGG:C00012 Peptide peptides chebi_ontology Peptid peptido peptidos CHEBI:16670 peptide CHEBI:16670 Peptide KEGG_COMPOUND peptides IUPAC Peptid ChEBI peptido ChEBI peptidos ChEBI A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond. 0 C9H12N2O6 InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 DRTQHJPVMGBUCF-XVFCMESISA-N 244.20146 244.06954 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O CHEBI:15296 CHEBI:27227 CHEBI:46386 CHEBI:46391 CHEBI:46460 CHEBI:9893 Beilstein:754904 CAS:58-96-8 DrugBank:DB02745 ECMDB:ECMDB00296 Gmelin:397474 HMDB:HMDB0000296 KEGG:C00299 KNApSAcK:C00019674 MetaCyc:URIDINE PDBeChem:URI PMID:12084455 PMID:15621516 PMID:16839635 PMID:17190852 PMID:22392515 PMID:22770225 Reaxys:754904 Wikipedia:Uridine YMDB:YMDB00127 URIDINE Uridine uridine chebi_ontology 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione 1-beta-D-ribofuranosyluracil Urd Uridin beta-Uridine u CHEBI:16704 uridine CHEBI:16704 Beilstein:754904 Beilstein CAS:58-96-8 ChemIDplus CAS:58-96-8 KEGG COMPOUND Gmelin:397474 Gmelin PMID:12084455 Europe PMC PMID:15621516 Europe PMC PMID:16839635 Europe PMC PMID:17190852 Europe PMC PMID:22392515 Europe PMC PMID:22770225 Europe PMC Reaxys:754904 Reaxys URIDINE PDBeChem Uridine KEGG_COMPOUND uridine IUPAC uridine UniProt 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione ChEBI 1-beta-D-ribofuranosyluracil HMDB Urd CBN Uridin ChemIDplus beta-Uridine HMDB u ChEBI A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics. 0 C8H12N2O3S InChI=1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1 NGHVIOIJCVXTGV-ALEPSDHESA-N 216.260 216.05686 C([C@H]1C(S[C@@]2([C@@H](C(N12)=O)N)[H])(C)C)(O)=O CHEBI:20705 CHEBI:2172 Beilstein:15080 Beilstein:959078 CAS:551-16-6 Gmelin:1876702 KEGG:C02954 PDBeChem:X1E PMID:12569987 PMID:1384868 PMID:14687482 PMID:1701026 PMID:20970923 PMID:21614893 PMID:24293403 PMID:24389703 PMID:24631718 PMID:25057428 PMID:26852849 PMID:26986755 PMID:6166603 Patent:US2941995 Reaxys:15080 Wikipedia:6-APA 6-Aminopenicillanic acid 6-amino-2,2-dimethylpenam-3alpha-carboxylic acid chebi_ontology (+)-6-aminopenicillanic acid (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-APA 6-Aminopenicillamine acid 6-Aminopenicillanate 6-Apa 6-Aps 6beta-aminopenicillanic acid Aminopenicillanic acid Penicin Penin Phenacyl 6-aminopenicillinate CHEBI:16705 6-aminopenicillanic acid CHEBI:16705 Beilstein:15080 Beilstein Beilstein:959078 Beilstein CAS:551-16-6 ChemIDplus CAS:551-16-6 KEGG COMPOUND Gmelin:1876702 Gmelin PMID:12569987 Europe PMC PMID:1384868 Europe PMC PMID:14687482 Europe PMC PMID:1701026 Europe PMC PMID:20970923 Europe PMC PMID:21614893 Europe PMC PMID:24293403 Europe PMC PMID:24389703 Europe PMC PMID:24631718 Europe PMC PMID:25057428 Europe PMC PMID:26852849 Europe PMC PMID:26986755 Europe PMC PMID:6166603 Europe PMC Reaxys:15080 Reaxys 6-Aminopenicillanic acid KEGG_COMPOUND 6-amino-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC (+)-6-aminopenicillanic acid ChEBI (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC 6-APA ChEBI 6-Aminopenicillamine acid ChemIDplus 6-Aminopenicillanate KEGG_COMPOUND 6-Apa ChemIDplus 6-Aps ChemIDplus 6beta-aminopenicillanic acid ChEBI Aminopenicillanic acid ChemIDplus Penicin ChemIDplus Penin ChemIDplus Phenacyl 6-aminopenicillinate ChemIDplus A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. 0 C6H6 InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H UHOVQNZJYSORNB-UHFFFAOYSA-N 78.11184 78.04695 c1ccccc1 CHEBI:13876 CHEBI:22703 CHEBI:3025 CHEBI:41187 Beilstein:969212 CAS:71-43-2 Gmelin:1671 HMDB:HMDB0001505 KEGG:C01407 PDBeChem:BNZ PMID:11684179 PMID:11993966 PMID:12857942 PMID:14677922 PMID:15468289 PMID:15935818 PMID:16161967 PMID:17373369 PMID:18072742 PMID:18407866 PMID:18409691 PMID:18836923 PMID:19228219 PMID:21325737 PMID:23088855 PMID:23222815 PMID:23534829 PMID:6353911 PMID:8124204 Reaxys:969212 UM-BBD_compID:c0142 Wikipedia:Benzene BENZENE Benzene benzene chebi_ontology Benzen Benzine Benzol Bicarburet of hydrogen Coal naphtha Mineral naphtha Phene Pyrobenzol Pyrobenzole [6]annulene benzole cyclohexatriene phenyl hydride CHEBI:16716 benzene CHEBI:16716 Beilstein:969212 Beilstein CAS:71-43-2 ChemIDplus CAS:71-43-2 KEGG COMPOUND CAS:71-43-2 NIST Chemistry WebBook Gmelin:1671 Gmelin PMID:11684179 Europe PMC PMID:11993966 Europe PMC PMID:12857942 Europe PMC PMID:14677922 Europe PMC PMID:15468289 Europe PMC PMID:15935818 Europe PMC PMID:16161967 Europe PMC PMID:17373369 Europe PMC PMID:18072742 Europe PMC PMID:18407866 Europe PMC PMID:18409691 Europe PMC PMID:18836923 Europe PMC PMID:19228219 Europe PMC PMID:21325737 Europe PMC PMID:23088855 Europe PMC PMID:23222815 Europe PMC PMID:23534829 Europe PMC PMID:6353911 Europe PMC PMID:8124204 Europe PMC Reaxys:969212 Reaxys UM-BBD_compID:c0142 UM-BBD BENZENE PDBeChem Benzene KEGG_COMPOUND benzene ChEBI benzene IUPAC benzene UniProt Benzen IUPAC Benzine UM-BBD Benzol ChemIDplus Bicarburet of hydrogen ChemIDplus Coal naphtha ChemIDplus Mineral naphtha ChemIDplus Phene ChemIDplus Pyrobenzol ChemIDplus Pyrobenzole ChemIDplus [6]annulene NIST_Chemistry_WebBook benzole NIST_Chemistry_WebBook cyclohexatriene UM-BBD phenyl hydride UM-BBD A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body. Wikipedia:Mineral_(nutrient) mineral nutrient chebi_ontology mineral nutrients nutrient mineral nutrient minerals CHEBI:167164 mineral nutrient CHEBI:167164 mineral nutrient ChEBI mineral nutrients ChEBI nutrient mineral ChEBI nutrient minerals ChEBI A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water. Wikipedia:Piscicide chebi_ontology piscicides CHEBI:167183 piscicide CHEBI:167183 piscicides ChEBI 0 C2H4NO2R 74.05870 74.02420 N[C@H]([*])C(O)=O CHEBI:12909 CHEBI:13625 CHEBI:20906 CHEBI:4097 KEGG:C00405 D-alpha-amino acid D-alpha-amino acids chebi_ontology D-Amino acid D-alpha-amino acids CHEBI:16733 D-alpha-amino acid CHEBI:16733 D-alpha-amino acid ChEBI D-alpha-amino acids IUPAC D-Amino acid KEGG_COMPOUND D-alpha-amino acids ChEBI Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001. chebi_ontology glycans CHEBI:167559 glycan CHEBI:167559 glycans ChEBI A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. 0 C7H6O3 InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) YGSDEFSMJLZEOE-UHFFFAOYSA-N 138.12070 138.03169 OC(=O)c1ccccc1O CHEBI:26597 CHEBI:45521 CHEBI:9006 Beilstein:774890 CAS:69-72-7 DrugBank:DB00936 Drug_Central:2416 Gmelin:3418 HMDB:HMDB0001895 KEGG:C00805 KEGG:D00097 KNApSAcK:C00000206 LINCS:LSM-4763 MetaCyc:CPD-110 PDBeChem:SAL PMID:11016405 PMID:12865403 PMID:1650428 PMID:19400653 PMID:19816125 PMID:22770225 PMID:29079364 PMID:32807953 PMID:3425858 Reaxys:774890 Wikipedia:Salicylic_Acid 2-hydroxybenzoic acid Salicylic acid chebi_ontology 2-HYDROXYBENZOIC ACID 2-carboxyphenol o-Hydroxybenzoic acid o-carboxyphenol o-hydroxybenzoic acid CHEBI:16914 salicylic acid CHEBI:16914 Beilstein:774890 Beilstein CAS:69-72-7 ChemIDplus CAS:69-72-7 KEGG COMPOUND CAS:69-72-7 NIST Chemistry WebBook Drug_Central:2416 DrugCentral Gmelin:3418 Gmelin PMID:11016405 Europe PMC PMID:12865403 Europe PMC PMID:1650428 Europe PMC PMID:19400653 Europe PMC PMID:19816125 Europe PMC PMID:22770225 Europe PMC PMID:29079364 Europe PMC PMID:32807953 Europe PMC PMID:3425858 Europe PMC Reaxys:774890 Reaxys 2-hydroxybenzoic acid IUPAC Salicylic acid KEGG_COMPOUND 2-HYDROXYBENZOIC ACID PDBeChem 2-carboxyphenol NIST_Chemistry_WebBook o-Hydroxybenzoic acid KEGG_COMPOUND o-carboxyphenol NIST_Chemistry_WebBook o-hydroxybenzoic acid NIST_Chemistry_WebBook 0 C20H37N3O13 InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6?,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20-/m1/s1 GRRNUXAQVGOGFE-NZSRVPFOSA-N 527.52010 527.23264 CN[C@H]1C[C@@H](N)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@@H]3O[C@@]4(O[C@H](C(N)CO)[C@H](O)[C@H](O)[C@H]4O)O[C@H]23)[C@@H]1O CHEBI:14426 CHEBI:24752 CHEBI:43202 CHEBI:5821 Beilstein:6755837 CAS:31282-04-9 KEGG:C01925 PDBeChem:HYG (1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-beta-D-talopyranoside HYGROMYCIN B Hygromycin B chebi_ontology Antibiotic A-396-II O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N(3)-methyl-D-streptamine CHEBI:16976 hygromycin B CHEBI:16976 Beilstein:6755837 Beilstein CAS:31282-04-9 ChemIDplus CAS:31282-04-9 KEGG COMPOUND (1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-beta-D-talopyranoside IUPAC HYGROMYCIN B PDBeChem Hygromycin B KEGG_COMPOUND Antibiotic A-396-II KEGG_COMPOUND O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N(3)-methyl-D-streptamine ChEBI An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. 0 H2O(C8H13NO5)n CHEBI:13962 CHEBI:23099 CHEBI:3596 CAS:1398-61-4 KEGG:C00461 KEGG:G10483 (1->4)-2-acetamido-2-deoxy-beta-D-glucan Chitin chitin chebi_ontology [1,4-(N-Acetyl-beta-D-glucosaminyl)]n [4)-beta-D-GlcpNAc(1->]n beta-1,4-Poly-N-acetyl-D-glucosamine CHEBI:17029 chitin CHEBI:17029 CAS:1398-61-4 KEGG COMPOUND (1->4)-2-acetamido-2-deoxy-beta-D-glucan IUPAC Chitin KEGG_COMPOUND chitin IUPAC chitin UniProt [1,4-(N-Acetyl-beta-D-glucosaminyl)]n KEGG_COMPOUND [4)-beta-D-GlcpNAc(1->]n IUPAC beta-1,4-Poly-N-acetyl-D-glucosamine KEGG_COMPOUND A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class 0 C21H39N7O12 InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1 UCSJYZPVAKXKNQ-HZYVHMACSA-N 581.57434 581.26567 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@@H](O[C@@H](C)[C@]1(O)C=O)O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]1NC(N)=N CHEBI:15119 CHEBI:26784 CHEBI:45745 CHEBI:9284 Beilstein:74498 CAS:57-92-1 DrugBank:DB01082 Drug_Central:2481 HMDB:HMDB0015214 KEGG:C00413 KEGG:D08531 MetaCyc:STREPTOMYCIN PDBeChem:SRY PMID:11228320 PMID:11905029 PMID:12118520 PMID:13030054 PMID:13116094 PMID:13136149 PMID:13596285 PMID:13691614 PMID:13985260 PMID:13990247 PMID:14623118 PMID:14828344 PMID:14852338 PMID:14939639 PMID:15081082 PMID:15137533 PMID:15207172 PMID:15686853 PMID:15736038 PMID:16904706 PMID:17105735 PMID:17238915 PMID:17429930 PMID:18173084 PMID:18916143 PMID:19052412 PMID:19335957 PMID:21350946 PMID:21362244 PMID:21593257 PMID:21937264 PMID:22101040 Pesticides:streptomycin Reaxys:74498 Wikipedia:Streptomycin N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine STREPTOMYCIN chebi_ontology 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside Kantrex SM [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine} streomycin streptomycin CHEBI:17076 streptomycin CHEBI:17076 Beilstein:74498 Beilstein CAS:57-92-1 ChemIDplus CAS:57-92-1 KEGG COMPOUND Drug_Central:2481 DrugCentral PMID:11228320 Europe PMC PMID:11905029 Europe PMC PMID:12118520 Europe PMC PMID:13030054 Europe PMC PMID:13116094 Europe PMC PMID:13136149 Europe PMC PMID:13596285 Europe PMC PMID:13691614 Europe PMC PMID:13985260 Europe PMC PMID:13990247 Europe PMC PMID:14623118 Europe PMC PMID:14828344 Europe PMC PMID:14852338 Europe PMC PMID:14939639 Europe PMC PMID:15081082 Europe PMC PMID:15137533 Europe PMC PMID:15207172 Europe PMC PMID:15686853 Europe PMC PMID:15736038 Europe PMC PMID:16904706 Europe PMC PMID:17105735 Europe PMC PMID:17238915 Europe PMC PMID:17429930 Europe PMC PMID:18173084 Europe PMC PMID:18916143 Europe PMC PMID:19052412 Europe PMC PMID:19335957 Europe PMC PMID:21350946 Europe PMC PMID:21362244 Europe PMC PMID:21593257 Europe PMC PMID:21937264 Europe PMC PMID:22101040 Europe PMC Pesticides:streptomycin Alan Wood's Pesticides Reaxys:74498 Reaxys N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine IUPAC STREPTOMYCIN PDBeChem 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside ChemIDplus Kantrex DrugBank SM KEGG_DRUG [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine} IUPAC streomycin ChEBI streptomycin KEGG_DRUG A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). 0 COR2 28.010 27.99491 [*]C([*])=O CHEBI:13427 CHEBI:13646 CHEBI:24974 CHEBI:6127 CHEBI:8742 KEGG:C01450 Wikipedia:Ketone Ketone ketones chebi_ontology Keton R-CO-R' a ketone cetone ketones CHEBI:17087 ketone CHEBI:17087 Ketone KEGG_COMPOUND ketones IUPAC Keton ChEBI R-CO-R' KEGG_COMPOUND a ketone UniProt cetone ChEBI ketones ChEBI -1 HO3S InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1 LSNNMFCWUKXFEE-UHFFFAOYSA-M 81.07214 80.96519 OS([O-])=O CHEBI:13367 CHEBI:5598 CAS:15181-46-1 Gmelin:1455 KEGG:C11481 PDBeChem:SO3 hydrogen(trioxidosulfate)(1-) hydrogensulfite(1-) hydrogentrioxosulfate(1-) hydrogentrioxosulfate(IV) hydroxidodioxidosulfate(1-) monohydrogentrioxosulfate chebi_ontology Bisulfite HSO3(-) HSO3- Hydrogen sulfite [SO2(OH)](-) bisulfite bisulphite hydrogen sulfite(1-) hydrosulfite anion CHEBI:17137 hydrogensulfite CHEBI:17137 CAS:15181-46-1 ChemIDplus CAS:15181-46-1 KEGG COMPOUND Gmelin:1455 Gmelin hydrogen(trioxidosulfate)(1-) IUPAC hydrogensulfite(1-) IUPAC hydrogentrioxosulfate(1-) IUPAC hydrogentrioxosulfate(IV) IUPAC hydroxidodioxidosulfate(1-) IUPAC monohydrogentrioxosulfate IUPAC Bisulfite KEGG_COMPOUND HSO3(-) IUPAC HSO3- KEGG_COMPOUND Hydrogen sulfite KEGG_COMPOUND [SO2(OH)](-) IUPAC bisulfite ChemIDplus bisulphite ChemIDplus hydrogen sulfite(1-) ChemIDplus hydrosulfite anion ChemIDplus A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. 0 C6H6N2O InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9) DFPAKSUCGFBDDF-UHFFFAOYSA-N 122.12472 122.04801 NC(=O)c1cccnc1 CHEBI:14645 CHEBI:25521 CHEBI:44258 CHEBI:7556 Beilstein:383619 CAS:98-92-0 DrugBank:DB02701 Drug_Central:1906 FooDB:FDB012485 Gmelin:3336 HMDB:HMDB0001406 KEGG:C00153 KEGG:D00036 KNApSAcK:C00000209 LINCS:LSM-5428 MetaCyc:NIACINAMIDE PDBeChem:NCA PMID:10884473 PMID:11355130 PMID:11814060 PMID:12014919 PMID:12487919 PMID:12519385 PMID:12709297 PMID:12782109 PMID:12890690 PMID:14729974 PMID:14757966 PMID:14871431 PMID:15497767 PMID:15563975 PMID:15780941 PMID:15807725 PMID:15834926 PMID:15995937 PMID:16029679 PMID:16209160 PMID:16596767 PMID:16766489 PMID:16871361 PMID:17021258 PMID:17129213 PMID:18234191 PMID:18316796 PMID:18368629 PMID:18373238 PMID:18389009 PMID:18514428 PMID:18930755 PMID:18987186 PMID:19212411 PMID:19539713 PMID:19544437 PMID:2026685 PMID:21503886 PMID:21891976 PMID:21918528 PMID:21926578 PMID:22067079 PMID:22160932 PMID:22207684 PMID:22232263 PMID:22281243 PMID:22359146 PMID:22361740 PMID:22407380 PMID:22456321 PMID:22536229 PMID:22543086 PMID:22626821 PMID:22699421 PMID:22709272 PMID:22763693 PMID:22770225 PMID:23016598 PMID:23028781 PMID:23043891 PMID:23047329 PMID:24027187 PMID:24077178 PMID:24559077 PMID:24635573 PMID:25504347 PMID:25561219 PMID:31710686 PMID:32249824 PMID:33196157 PMID:33471934 PMID:8620561 PMID:8767167 PMID:9518388 Patent:US2904552 Patent:US2993051 Reaxys:383619 Wikipedia:Nicotinamide nicotinamide pyridine-3-carboxamide chebi_ontology 3-carbamoylpyridine 3-pyridinecarboxamide Niacinamide Nicotinamid Nicotinsaeureamid Nikotinamid Nikotinsaeureamid Vitamin PP beta-pyridinecarboxamide m-(aminocarbonyl)pyridine niacin niamide nicotinamida nicotinamide nicotinamidum nicotine acid amide nicotine amide nicotinic acid amide nicotinic amide nicotylamide pyridine-3-carboxylic acid amide vitamin B3 CHEBI:17154 nicotinamide CHEBI:17154 Beilstein:383619 Beilstein CAS:98-92-0 ChemIDplus CAS:98-92-0 KEGG COMPOUND CAS:98-92-0 NIST Chemistry WebBook Drug_Central:1906 DrugCentral Gmelin:3336 Gmelin PMID:10884473 Europe PMC PMID:11355130 Europe PMC PMID:11814060 Europe PMC PMID:12014919 Europe PMC PMID:12487919 Europe PMC PMID:12519385 Europe PMC PMID:12709297 Europe PMC PMID:12782109 Europe PMC PMID:12890690 Europe PMC PMID:14729974 Europe PMC PMID:14757966 Europe PMC PMID:14871431 Europe PMC PMID:15497767 Europe PMC PMID:15563975 Europe PMC PMID:15780941 Europe PMC PMID:15807725 Europe PMC PMID:15834926 Europe PMC PMID:15995937 Europe PMC PMID:16029679 Europe PMC PMID:16209160 Europe PMC PMID:16596767 Europe PMC PMID:16766489 Europe PMC PMID:16871361 Europe PMC PMID:17021258 Europe PMC PMID:17129213 Europe PMC PMID:18234191 Europe PMC PMID:18316796 Europe PMC PMID:18368629 Europe PMC PMID:18373238 Europe PMC PMID:18389009 Europe PMC PMID:18514428 Europe PMC PMID:18930755 Europe PMC PMID:18987186 Europe PMC PMID:19212411 Europe PMC PMID:19539713 Europe PMC PMID:19544437 Europe PMC PMID:2026685 Europe PMC PMID:21503886 Europe PMC PMID:21891976 Europe PMC PMID:21918528 Europe PMC PMID:21926578 Europe PMC PMID:22067079 Europe PMC PMID:22160932 Europe PMC PMID:22207684 Europe PMC PMID:22232263 Europe PMC PMID:22281243 Europe PMC PMID:22359146 Europe PMC PMID:22361740 Europe PMC PMID:22407380 Europe PMC PMID:22456321 Europe PMC PMID:22536229 Europe PMC PMID:22543086 Europe PMC PMID:22626821 Europe PMC PMID:22699421 Europe PMC PMID:22709272 Europe PMC PMID:22763693 Europe PMC PMID:22770225 Europe PMC PMID:23016598 Europe PMC PMID:23028781 Europe PMC PMID:23043891 Europe PMC PMID:23047329 Europe PMC PMID:24027187 Europe PMC PMID:24077178 Europe PMC PMID:24559077 Europe PMC PMID:24635573 Europe PMC PMID:25504347 Europe PMC PMID:25561219 Europe PMC PMID:31710686 Europe PMC PMID:32249824 Europe PMC PMID:33196157 Europe PMC PMID:33471934 Europe PMC PMID:8620561 Europe PMC PMID:8767167 Europe PMC PMID:9518388 Europe PMC Reaxys:383619 Reaxys nicotinamide UniProt pyridine-3-carboxamide IUPAC 3-carbamoylpyridine ChemIDplus 3-pyridinecarboxamide NIST_Chemistry_WebBook Niacinamide KEGG_COMPOUND Nicotinamid ChEBI Nicotinsaeureamid ChEBI Nikotinamid ChemIDplus Nikotinsaeureamid ChEBI Vitamin PP KEGG_COMPOUND beta-pyridinecarboxamide ChemIDplus beta-pyridinecarboxamide NIST_Chemistry_WebBook m-(aminocarbonyl)pyridine ChemIDplus niacin ChEBI niamide ChemIDplus nicotinamida WHO_MedNet nicotinamide WHO_MedNet nicotinamidum WHO_MedNet nicotine acid amide ChemIDplus nicotine amide ChemIDplus nicotinic acid amide ChemIDplus nicotinic amide ChemIDplus nicotylamide ChemIDplus pyridine-3-carboxylic acid amide ChemIDplus vitamin B3 ChemIDplus An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae. chebi_ontology amebicide amebicides amoebicide amoebicides anti-amoebic agent anti-amoebic agents anti-amoebic drug anti-amoebic drugs antiamoebic antiamoebic agents antiamoebic drug antiamoebic drugs antiamoebics CHEBI:171664 antiamoebic agent CHEBI:171664 amebicide ChEBI amebicides ChEBI amoebicide ChEBI amoebicides ChEBI anti-amoebic agent ChEBI anti-amoebic agents ChEBI anti-amoebic drug ChEBI anti-amoebic drugs ChEBI antiamoebic ChEBI antiamoebic agents ChEBI antiamoebic drug ChEBI antiamoebic drugs ChEBI antiamoebics ChEBI Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. 0 C5H9NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 115.13050 115.06333 OC(=O)[C@@H]1CCCN1 CHEBI:13154 CHEBI:184637 CHEBI:21373 CHEBI:42067 CHEBI:45040 CHEBI:45100 CHEBI:45159 CHEBI:6286 Beilstein:80810 CAS:147-85-3 DrugBank:DB00172 Drug_Central:4125 Gmelin:50152 HMDB:HMDB0000162 KEGG:C00148 KEGG:D00035 KNApSAcK:C00001388 MetaCyc:PRO PDBeChem:PRO PMID:11076505 PMID:12770004 PMID:14975886 PMID:15576824 PMID:15838615 PMID:15894682 PMID:15973048 PMID:16033917 PMID:16190672 PMID:16501220 PMID:16656443 PMID:16657874 PMID:16668324 PMID:17127472 PMID:17608428 PMID:18551589 PMID:18802692 PMID:18973300 PMID:19215998 PMID:19580280 PMID:19656302 PMID:19688381 PMID:19811425 PMID:22139509 PMID:22201772 PMID:22451406 PMID:22475019 PMID:22482728 PMID:22491679 PMID:22770225 Reaxys:80810 Wikipedia:L-proline L-Proline L-proline chebi_ontology (-)-(S)-proline (-)-2-pyrrolidinecarboxylic acid (-)-proline (2S)-pyrrolidine-2-carboxylic acid (S)-2-carboxypyrrolidine (S)-2-pyrrolidinecarboxylic acid (S)-pyrrolidine-2-carboxylic acid 2-Pyrrolidinecarboxylic acid L-(-)-proline L-Prolin L-alpha-pyrrolidinecarboxylic acid L-pyrrolidine-2-carboxylic acid P PROLINE prolina proline prolinum CHEBI:17203 L-proline CHEBI:17203 Beilstein:80810 Beilstein CAS:147-85-3 ChemIDplus CAS:147-85-3 KEGG COMPOUND CAS:147-85-3 NIST Chemistry WebBook Drug_Central:4125 DrugCentral Gmelin:50152 Gmelin PMID:11076505 Europe PMC PMID:12770004 Europe PMC PMID:14975886 Europe PMC PMID:15576824 Europe PMC PMID:15838615 Europe PMC PMID:15894682 Europe PMC PMID:15973048 Europe PMC PMID:16033917 Europe PMC PMID:16190672 Europe PMC PMID:16501220 Europe PMC PMID:16656443 Europe PMC PMID:16657874 Europe PMC PMID:16668324 Europe PMC PMID:17127472 Europe PMC PMID:17608428 Europe PMC PMID:18551589 Europe PMC PMID:18802692 Europe PMC PMID:18973300 Europe PMC PMID:19215998 Europe PMC PMID:19580280 Europe PMC PMID:19656302 Europe PMC PMID:19688381 Europe PMC PMID:19811425 Europe PMC PMID:22139509 Europe PMC PMID:22201772 Europe PMC PMID:22451406 Europe PMC PMID:22475019 Europe PMC PMID:22482728 Europe PMC PMID:22491679 Europe PMC PMID:22770225 Europe PMC Reaxys:80810 Reaxys L-Proline KEGG_COMPOUND L-proline IUPAC (-)-(S)-proline NIST_Chemistry_WebBook (-)-2-pyrrolidinecarboxylic acid ChemIDplus (-)-proline ChemIDplus (2S)-pyrrolidine-2-carboxylic acid IUPAC (S)-2-carboxypyrrolidine DrugBank (S)-2-pyrrolidinecarboxylic acid ChemIDplus (S)-pyrrolidine-2-carboxylic acid ChEBI 2-Pyrrolidinecarboxylic acid KEGG_COMPOUND L-(-)-proline NIST_Chemistry_WebBook L-Prolin ChEBI L-alpha-pyrrolidinecarboxylic acid ChemIDplus L-pyrrolidine-2-carboxylic acid ChemIDplus P ChEBI PROLINE PDBeChem prolina ChemIDplus proline ChemIDplus prolinum ChemIDplus An aldohexose used as a source of energy and metabolic intermediate. 0 C6H12O6 180.15588 180.06339 CHEBI:14313 CHEBI:24277 CHEBI:33929 CHEBI:5418 CAS:50-99-7 KEGG:C00293 Wikipedia:Glucose Glucose gluco-hexose glucose chebi_ontology DL-glucose Glc Glukose CHEBI:17234 glucose CHEBI:17234 CAS:50-99-7 KEGG COMPOUND Glucose KEGG_COMPOUND gluco-hexose IUPAC glucose IUPAC DL-glucose ChEBI Glc JCBN Glukose ChEBI A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens. 0 C6H7N InChI=1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 93.12650 93.05785 Nc1ccccc1 CHEBI:13834 CHEBI:22561 CHEBI:2732 CHEBI:40796 Beilstein:605631 CAS:62-53-3 DrugBank:DB06728 Gmelin:2796 HMDB:HMDB0003012 KEGG:C00292 MetaCyc:ANILINE PDBeChem:ANL PMID:11304127 PMID:17135213 PMID:23821252 PMID:3779628 PMID:6205897 Reaxys:605631 Wikipedia:Aniline ANILINE Aniline aniline chebi_ontology Anilin Benzenamine Phenylamine aminobenzene aminophen benzeneamine kyanol CHEBI:17296 aniline CHEBI:17296 Beilstein:605631 Beilstein CAS:62-53-3 ChemIDplus CAS:62-53-3 KEGG COMPOUND CAS:62-53-3 NIST Chemistry WebBook Gmelin:2796 Gmelin PMID:11304127 Europe PMC PMID:17135213 Europe PMC PMID:23821252 Europe PMC PMID:3779628 Europe PMC PMID:6205897 Europe PMC Reaxys:605631 Reaxys ANILINE PDBeChem Aniline KEGG_COMPOUND aniline IUPAC aniline UniProt Anilin NIST_Chemistry_WebBook Benzenamine KEGG_COMPOUND Phenylamine KEGG_COMPOUND aminobenzene ChemIDplus aminophen ChemIDplus benzeneamine NIST_Chemistry_WebBook kyanol NIST_Chemistry_WebBook Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. PMID:32015325 PMID:32256352 PMID:32413317 PMID:33495651 Wikipedia:Ferroptosis chebi_ontology ferroptosis inhibitors CHEBI:173084 ferroptosis inhibitor CHEBI:173084 PMID:32015325 SUBMITTER PMID:32256352 Europe PMC PMID:32413317 Europe PMC PMID:33495651 Europe PMC ferroptosis inhibitors ChEBI Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6. 0 C9H11N2O4SR 243.26000 243.04395 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC([*])=O)C(O)=O CHEBI:14742 CHEBI:25869 CHEBI:7961 KEGG:C00395 PMID:11851248 PMID:12833570 PMID:1502708 PMID:16033609 PMID:7061385 PMID:7798534 Wikipedia:Penicillin Penicillin penicillins chebi_ontology penicillins CHEBI:17334 penicillin CHEBI:17334 PMID:11851248 Europe PMC PMID:12833570 Europe PMC PMID:1502708 Europe PMC PMID:16033609 Europe PMC PMID:7061385 Europe PMC PMID:7798534 Europe PMC Penicillin KEGG_COMPOUND penicillins IUPAC penicillins ChEBI A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3). -2 O3S InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2 LSNNMFCWUKXFEE-UHFFFAOYSA-L 80.06420 79.95791 [O-]S([O-])=O CHEBI:15139 CHEBI:45548 CAS:14265-45-3 Gmelin:1449 PDBeChem:SO3 sulfite trioxidosulfate(2-) trioxosulfate(2-) trioxosulfate(IV) chebi_ontology SO3 SO3(2-) SULFITE ION [SO3](2-) sulphite CHEBI:17359 sulfite CHEBI:17359 CAS:14265-45-3 ChemIDplus Gmelin:1449 Gmelin sulfite IUPAC sulfite UniProt trioxidosulfate(2-) IUPAC trioxosulfate(2-) IUPAC trioxosulfate(IV) IUPAC SO3 ChEBI SO3(2-) IUPAC SULFITE ION PDBeChem [SO3](2-) IUPAC sulphite ChEBI A straight-chain saturated fatty acid containing five carbon atoms. 0 C5H10O2 InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7) NQPDZGIKBAWPEJ-UHFFFAOYSA-N 102.13170 102.06808 CCCCC(O)=O CHEBI:113448 CHEBI:27263 CHEBI:27264 CHEBI:43606 CHEBI:44803 CHEBI:7980 Beilstein:969454 CAS:109-52-4 DrugBank:DB02406 Gmelin:26714 HMDB:HMDB0000892 KEGG:C00803 KNApSAcK:C00001208 LIPID_MAPS_instance:LMFA01010005 PDBeChem:LEA PMID:20507156 PPDB:3130 Reaxys:969454 Wikipedia:Valeric_acid Valeric acid pentanoic acid chebi_ontology 1-butanecarboxylic acid CH3-[CH2]3-COOH PENTANOIC ACID Pentanoate Pentanoic acid Valerate Valerianic acid Valeriansaeure n-BuCOOH n-Pentanoate n-Valeric acid n-pentanoic acid n-valeric acid pentoic acid propylacetic acid valeric acid, normal CHEBI:17418 valeric acid CHEBI:17418 Beilstein:969454 Beilstein CAS:109-52-4 ChemIDplus CAS:109-52-4 KEGG COMPOUND CAS:109-52-4 NIST Chemistry WebBook Gmelin:26714 Gmelin LIPID_MAPS_instance:LMFA01010005 LIPID MAPS PMID:20507156 Europe PMC Reaxys:969454 Reaxys Valeric acid KEGG_COMPOUND pentanoic acid IUPAC 1-butanecarboxylic acid ChemIDplus 1-butanecarboxylic acid NIST_Chemistry_WebBook CH3-[CH2]3-COOH IUPAC PENTANOIC ACID PDBeChem Pentanoate KEGG_COMPOUND Pentanoic acid KEGG_COMPOUND Valerate KEGG_COMPOUND Valerianic acid KEGG_COMPOUND Valeriansaeure ChEBI n-BuCOOH ChEBI n-Pentanoate KEGG_COMPOUND n-Valeric acid KEGG_COMPOUND n-pentanoic acid ChemIDplus n-valeric acid ChemIDplus pentoic acid ChEBI propylacetic acid ChemIDplus valeric acid, normal ChemIDplus A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group. 0 CHOR 29.018 29.00274 [H]C([*])=O CHEBI:13432 CHEBI:13753 CHEBI:13805 CHEBI:13806 CHEBI:22291 CHEBI:2554 CHEBI:8750 KEGG:C00071 Aldehyde aldehyde aldehydes chebi_ontology Aldehyd RC(=O)H RCHO aldehido aldehidos aldehydes aldehydum an aldehyde CHEBI:17478 aldehyde CHEBI:17478 Aldehyde KEGG_COMPOUND aldehyde ChEBI aldehyde IUPAC aldehydes IUPAC Aldehyd ChEBI RC(=O)H IUPAC RCHO KEGG_COMPOUND aldehido ChEBI aldehidos ChEBI aldehydes ChEBI aldehydum ChEBI an aldehyde UniProt A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. 0 C10H12N5O6P InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 329.20614 329.05252 Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O CHEBI:11673 CHEBI:1325 CHEBI:19827 CHEBI:41588 Beilstein:52645 CAS:60-92-4 DrugBank:DB02527 HMDB:HMDB0000058 KEGG:C00575 KNApSAcK:C00001497 MetaCyc:CAMP PDBeChem:CMP PMID:16295522 PMID:18372334 PMID:22770225 Reaxys:52645 Wikipedia:Cyclic_AMP 3',5'-Cyclic AMP adenosine 3',5'-(hydrogen phosphate) chebi_ontology ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE Adenosine 3',5'-cyclic phosphate Adenosine 3',5'-phosphate Cyclic AMP Cyclic adenylic acid adenosine 3',5'-cyclic monophosphate cAMP CHEBI:17489 3',5'-cyclic AMP CHEBI:17489 Beilstein:52645 Beilstein CAS:60-92-4 ChemIDplus CAS:60-92-4 KEGG COMPOUND CAS:60-92-4 NIST Chemistry WebBook PMID:16295522 Europe PMC PMID:18372334 Europe PMC PMID:22770225 Europe PMC Reaxys:52645 Reaxys 3',5'-Cyclic AMP KEGG_COMPOUND adenosine 3',5'-(hydrogen phosphate) IUPAC ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE PDBeChem Adenosine 3',5'-cyclic phosphate KEGG_COMPOUND Adenosine 3',5'-phosphate KEGG_COMPOUND Cyclic AMP KEGG_COMPOUND Cyclic adenylic acid KEGG_COMPOUND adenosine 3',5'-cyclic monophosphate NIST_Chemistry_WebBook cAMP KEGG_COMPOUND A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). 0 RH2 2.016 2.01565 *([H])[H] CHEBI:13233 CHEBI:15018 CHEBI:8785 KEGG:C00030 chebi_ontology AH2 Donor Hydrogen-donor Reduced acceptor CHEBI:17499 hydrogen donor CHEBI:17499 AH2 KEGG_COMPOUND AH2 UniProt Donor KEGG_COMPOUND Hydrogen-donor KEGG_COMPOUND Reduced acceptor KEGG_COMPOUND A pseudohalide anion that is the conjugate base of hydrogen cyanide. -1 CN InChI=1S/CN/c1-2/q-1 XFXPMWWXUTWYJX-UHFFFAOYSA-N 26.01740 26.00362 [C-]#N CHEBI:14038 CHEBI:3969 CHEBI:41780 Beilstein:1900509 CAS:57-12-5 Gmelin:89 HMDB:HMDB0002084 KEGG:C00177 MetaCyc:CPD-13584 PDBeChem:CYN PMID:11386635 PMID:14871577 PMID:17554165 PMID:7839575 Reaxys:1900509 Wikipedia:Cyanide Cyanide cyanide nitridocarbonate(1-) chebi_ontology CN(-) CN- CYANIDE ION Prussiate Zyanid CHEBI:17514 cyanide CHEBI:17514 Beilstein:1900509 Beilstein CAS:57-12-5 ChemIDplus CAS:57-12-5 KEGG COMPOUND CAS:57-12-5 NIST Chemistry WebBook Gmelin:89 Gmelin PMID:11386635 Europe PMC PMID:14871577 Europe PMC PMID:17554165 Europe PMC PMID:7839575 Europe PMC Reaxys:1900509 Reaxys Cyanide ChEBI Cyanide KEGG_COMPOUND cyanide IUPAC nitridocarbonate(1-) IUPAC CN(-) IUPAC CN- KEGG_COMPOUND CYANIDE ION PDBeChem Prussiate KEGG_COMPOUND Zyanid ChEBI A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group). 0 (CH2O)nC2H6O2 CHEBI:13754 CHEBI:22298 CHEBI:2556 KEGG:C00717 Wikipedia:Glycerin Alditol alditol chebi_ontology Glycitol Sugar alcohol alditols CHEBI:17522 alditol CHEBI:17522 Alditol KEGG_COMPOUND alditol UniProt Glycitol KEGG_COMPOUND Sugar alcohol KEGG_COMPOUND alditols ChEBI The carbon oxoanion resulting from the removal of a proton from carbonic acid. -1 CHO3 InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1 BVKZGUZCCUSVTD-UHFFFAOYSA-M 61.01684 60.99312 OC([O-])=O CHEBI:13363 CHEBI:22863 CHEBI:40961 CHEBI:5589 Beilstein:3903504 CAS:71-52-3 Gmelin:49249 HMDB:HMDB0000595 KEGG:C00288 MetaCyc:HCO3 PDBeChem:BCT PMID:17215880 PMID:17505962 PMID:18439416 PMID:28732801 PMID:29150416 PMID:29460248 PMID:29466234 PMID:4208463 Wikipedia:Bicarbonate Hydrogencarbonate hydrogen(trioxidocarbonate)(1-) hydrogencarbonate hydrogencarbonate(1-) hydrogentrioxocarbonate(1-) hydrogentrioxocarbonate(IV) hydroxidodioxidocarbonate(1-) chebi_ontology Acid carbonate BICARBONATE ION Bicarbonate HCO3(-) HCO3- [CO2(OH)](-) hydrogen carbonate CHEBI:17544 hydrogencarbonate CHEBI:17544 Beilstein:3903504 Beilstein CAS:71-52-3 ChemIDplus Gmelin:49249 Gmelin PMID:17215880 Europe PMC PMID:17505962 Europe PMC PMID:18439416 Europe PMC PMID:28732801 Europe PMC PMID:29150416 Europe PMC PMID:29460248 Europe PMC PMID:29466234 Europe PMC PMID:4208463 Europe PMC Hydrogencarbonate KEGG_COMPOUND hydrogen(trioxidocarbonate)(1-) IUPAC hydrogencarbonate IUPAC hydrogencarbonate UniProt hydrogencarbonate(1-) IUPAC hydrogentrioxocarbonate(1-) IUPAC hydrogentrioxocarbonate(IV) IUPAC hydroxidodioxidocarbonate(1-) IUPAC Acid carbonate KEGG_COMPOUND BICARBONATE ION PDBeChem Bicarbonate KEGG_COMPOUND HCO3(-) IUPAC HCO3- KEGG_COMPOUND [CO2(OH)](-) IUPAC hydrogen carbonate PDBeChem A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. 0 C4H4N2O2 InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8) ISAKRJDGNUQOIC-UHFFFAOYSA-N 112.08684 112.02728 O=c1cc[nH]c(=O)[nH]1 CHEBI:15288 CHEBI:27210 CHEBI:46375 CHEBI:9882 Beilstein:606623 CAS:66-22-8 DrugBank:DB03419 Gmelin:2896 HMDB:HMDB0000300 KEGG:C00106 KEGG:D00027 KNApSAcK:C00001513 MetaCyc:URACIL PDBeChem:URA PMID:11279060 PMID:12855717 PMID:15274295 PMID:16834123 PMID:17439666 PMID:18533995 PMID:18815805 PMID:19175333 PMID:22020693 PMID:22074393 PMID:22120518 PMID:22171528 PMID:22237209 PMID:22299724 PMID:22356544 PMID:22447672 PMID:22483865 PMID:22567906 PMID:22685418 PMID:3654008 Reaxys:606623 Wikipedia:Uracil URACIL Uracil pyrimidine-2,4(1H,3H)-dione uracil chebi_ontology 2,4(1H,3H)-pyrimidinedione 2,4-Dioxopyrimidine 2,4-Pyrimidinedione U Ura Urazil CHEBI:17568 uracil CHEBI:17568 Beilstein:606623 Beilstein CAS:66-22-8 ChemIDplus CAS:66-22-8 KEGG COMPOUND CAS:66-22-8 NIST Chemistry WebBook Gmelin:2896 Gmelin PMID:11279060 Europe PMC PMID:12855717 Europe PMC PMID:15274295 Europe PMC PMID:16834123 Europe PMC PMID:17439666 Europe PMC PMID:18533995 Europe PMC PMID:18815805 Europe PMC PMID:19175333 Europe PMC PMID:22020693 Europe PMC PMID:22074393 Europe PMC PMID:22120518 Europe PMC PMID:22171528 Europe PMC PMID:22237209 Europe PMC PMID:22299724 Europe PMC PMID:22356544 Europe PMC PMID:22447672 Europe PMC PMID:22483865 Europe PMC PMID:22567906 Europe PMC PMID:22685418 Europe PMC PMID:3654008 Europe PMC Reaxys:606623 Reaxys URACIL PDBeChem Uracil KEGG_COMPOUND pyrimidine-2,4(1H,3H)-dione IUPAC uracil UniProt 2,4(1H,3H)-pyrimidinedione NIST_Chemistry_WebBook 2,4-Dioxopyrimidine HMDB 2,4-Pyrimidinedione HMDB U ChEBI Ura CBN Urazil ChEBI Any D-aldose having a chain of six carbon atoms in the molecule. 0 C6H12O6 180.156 180.06339 CHEBI:12990 CHEBI:21038 chebi_ontology D-aldohexoses CHEBI:17608 D-aldohexose CHEBI:17608 D-aldohexoses ChEBI 0 C18H36N4O11 InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1 SBUJHOSQTJFQJX-NOAMYHISSA-N 484.49860 484.23806 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O CHEBI:14487 CHEBI:24945 CHEBI:24947 CHEBI:43482 CHEBI:6106 Beilstein:61647 CAS:59-01-8 DrugBank:DB01172 Drug_Central:1519 Gmelin:2044856 KEGG:C01822 LINCS:LSM-5261 PDBeChem:KAN PMID:22907688 PMID:24336356 PMID:24566637 VSDB:1921 Wikipedia:Kanamycin (1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside KANAMYCIN A Kanamycin A chebi_ontology 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-alpha-D-glucoside 4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine CHEBI:17630 kanamycin A CHEBI:17630 Beilstein:61647 Beilstein CAS:59-01-8 ChemIDplus CAS:59-01-8 KEGG COMPOUND Drug_Central:1519 DrugCentral Gmelin:2044856 Gmelin PMID:22907688 Europe PMC PMID:24336356 Europe PMC PMID:24566637 Europe PMC (1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside IUPAC KANAMYCIN A PDBeChem Kanamycin A KEGG_COMPOUND 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-alpha-D-glucoside ChemIDplus 4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside ChemIDplus O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine ChemIDplus A glucose with D-configuration. 0 C6H12O6 180.15588 180.06339 CHEBI:12965 CHEBI:20999 CAS:50-99-7 D-gluco-hexose D-glucose chebi_ontology D(+)-glucose D-(+)-glucose Traubenzucker dextrose grape sugar CHEBI:17634 D-glucose CHEBI:17634 CAS:50-99-7 ChemIDplus CAS:50-99-7 NIST Chemistry WebBook D-gluco-hexose IUPAC D-glucose IUPAC D(+)-glucose ChemIDplus D-(+)-glucose NIST_Chemistry_WebBook Traubenzucker ChemIDplus dextrose NIST_Chemistry_WebBook grape sugar ChemIDplus Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. PMID:23372317 PMID:28580190 PMID:30885572 PMID:33144142 PMID:33973253 PMID:34606237 Wikipedia:Geroprotector chebi_ontology anti-aging agent anti-aging agents anti-aging drug anti-aging drugs geroprotective agent geroprotective agents geroprotectors CHEBI:176497 geroprotector CHEBI:176497 PMID:23372317 Europe PMC PMID:28580190 Europe PMC PMID:30885572 Europe PMC PMID:33144142 Europe PMC PMID:33973253 Europe PMC PMID:34606237 Europe PMC anti-aging agent ChEBI anti-aging agents ChEBI anti-aging drug ChEBI anti-aging drugs ChEBI geroprotective agent ChEBI geroprotective agents ChEBI geroprotectors ChEBI A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae. 0 C46H77NO17 InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 916.10010 915.51915 CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC CHEBI:15275 CHEBI:27172 CHEBI:46150 CHEBI:9787 CAS:1401-69-0 HMDB:HMDB0034108 KEGG:C01457 KEGG:D02490 LIPID_MAPS_instance:LMPK04000004 MetaCyc:TYLOSIN PDBeChem:TYK PMID:18836909 PMID:23013044 PMID:23352520 PMID:23397987 PMID:23398744 PMID:23928021 PMID:23985521 PMID:24063615 PMID:24113548 PMID:24201036 PMID:24270892 PMID:24393633 PMID:7867337 Patent:US2004082524 Reaxys:4651020 Wikipedia:Tylosin Tylosin [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyloxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside chebi_ontology Tylan Tylocine Tylosin A tilosina tylosin tylosine tylosinum CHEBI:17658 tylosin CHEBI:17658 CAS:1401-69-0 ChemIDplus CAS:1401-69-0 KEGG COMPOUND LIPID_MAPS_instance:LMPK04000004 LIPID MAPS PMID:18836909 Europe PMC PMID:23013044 Europe PMC PMID:23352520 Europe PMC PMID:23397987 Europe PMC PMID:23398744 Europe PMC PMID:23928021 Europe PMC PMID:23985521 Europe PMC PMID:24063615 Europe PMC PMID:24113548 Europe PMC PMID:24201036 Europe PMC PMID:24270892 Europe PMC PMID:24393633 Europe PMC PMID:7867337 Europe PMC Reaxys:4651020 Reaxys Tylosin KEGG_COMPOUND [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyloxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside IUPAC Tylan ChemIDplus Tylocine ChemIDplus Tylosin A ChemIDplus tilosina ChemIDplus tylosin ChemIDplus tylosine ChemIDplus tylosinum ChemIDplus Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms). vitamin B3 chebi_ontology vitamin B-3 vitamin B3 vitamer vitamin B3 vitamers vitamins B3 CHEBI:176839 vitamin B3 CHEBI:176839 vitamin B3 ChEBI vitamin B-3 ChEBI vitamin B3 vitamer ChEBI vitamin B3 vitamers ChEBI vitamins B3 ChEBI An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. 0 C11H12Cl2N2O5 InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 323.130 322.01233 C1=C([C@H]([C@H](NC(C(Cl)Cl)=O)CO)O)C=CC(=C1)[N+]([O-])=O CHEBI:13965 CHEBI:23106 CHEBI:23108 CHEBI:3603 CHEBI:47327 Beilstein:2225532 CAS:56-75-7 Chemspider:5744 DrugBank:DB00446 Drug_Central:589 HMDB:HMDB0014589 KEGG:C00918 KEGG:D00104 LINCS:LSM-5256 MetaCyc:CHLORAMPHENICOL PDBeChem:CLM PMID:11468347 PMID:12217690 PMID:16659995 PMID:16897441 PMID:17217404 PMID:17692887 PMID:17963326 PMID:18559535 PMID:18657290 PMID:18794387 PMID:23142491 PMID:23317719 PMID:23395526 PMID:23494278 PMID:23512826 PMID:23698443 PMID:657786 PMID:6653106 PMID:7040026 Patent:GB795131 Patent:GB796901 Patent:US2483871 Patent:US2483884 Patent:US2483892 Patent:US2839577 Pesticides:chloramphenicol VSDB:1835 Wikipedia:Chloramphenicol 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide CHLORAMPHENICOL Chloramphenicol chloramphenicol chebi_ontology (-)-chloramphenicol Amphicol Chloramex Chlorocid Chlorocol Chloromycetin D-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide D-(-)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol Econochlor Fenicol Globenicol Halomycetin Oleomycetin Sificetina chloramphenicol chloramphenicolum chlornitromycin cloramfenicol laevomycetinum levomicetina levomycetin CHEBI:17698 chloramphenicol CHEBI:17698 Beilstein:2225532 Beilstein CAS:56-75-7 ChemIDplus CAS:56-75-7 NIST Chemistry WebBook Drug_Central:589 DrugCentral PMID:11468347 Europe PMC PMID:12217690 Europe PMC PMID:16659995 Europe PMC PMID:16897441 Europe PMC PMID:17217404 Europe PMC PMID:17692887 Europe PMC PMID:17963326 Europe PMC PMID:18559535 Europe PMC PMID:18657290 Europe PMC PMID:18794387 Europe PMC PMID:23142491 Europe PMC PMID:23317719 Europe PMC PMID:23395526 Europe PMC PMID:23494278 Europe PMC PMID:23512826 Europe PMC PMID:23698443 Europe PMC PMID:657786 Europe PMC PMID:6653106 Europe PMC PMID:7040026 Europe PMC Pesticides:chloramphenicol Alan Wood's Pesticides 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide IUPAC CHLORAMPHENICOL PDBeChem Chloramphenicol KEGG_COMPOUND chloramphenicol UniProt (-)-chloramphenicol ChEBI Amphicol KEGG_DRUG Chloramex ChemIDplus Chlorocid ChemIDplus Chlorocol ChemIDplus Chloromycetin ChemIDplus D-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide ChemIDplus D-(-)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol ChemIDplus Econochlor KEGG_DRUG Fenicol ChemIDplus Globenicol ChemIDplus Halomycetin ChemIDplus Oleomycetin ChemIDplus Sificetina ChemIDplus chloramphenicol WHO_MedNet chloramphenicolum WHO_MedNet chlornitromycin ChEBI cloramfenicol WHO_MedNet laevomycetinum ChemIDplus levomicetina ChemIDplus levomycetin ChemIDplus The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group. 0 CH4O InChI=1S/CH4O/c1-2/h2H,1H3 OKKJLVBELUTLKV-UHFFFAOYSA-N 32.04186 32.02621 CO CHEBI:14588 CHEBI:25227 CHEBI:44080 CHEBI:44553 CHEBI:6816 Beilstein:1098229 CAS:67-56-1 Gmelin:449 HMDB:HMDB0001875 KEGG:C00132 KEGG:D02309 MetaCyc:METOH PDBeChem:MOH PMID:11141607 PMID:11430978 PMID:11489599 PMID:11680737 PMID:11684179 PMID:14012711 PMID:14678513 PMID:14760634 PMID:15172721 PMID:15906011 PMID:16705261 PMID:17451998 PMID:17733096 PMID:19064074 PMID:19850112 PMID:20314698 Reaxys:1098229 UM-BBD_compID:c0132 Wikipedia:Methanol METHANOL Methanol methanol chebi_ontology CH3OH MeOH Methyl alcohol Methylalkohol carbinol spirit of wood wood alcohol wood naphtha wood spirit CHEBI:17790 methanol CHEBI:17790 Beilstein:1098229 Beilstein CAS:67-56-1 ChemIDplus CAS:67-56-1 KEGG COMPOUND CAS:67-56-1 NIST Chemistry WebBook Gmelin:449 Gmelin PMID:11141607 Europe PMC PMID:11430978 Europe PMC PMID:11489599 Europe PMC PMID:11680737 Europe PMC PMID:11684179 Europe PMC PMID:14012711 Europe PMC PMID:14678513 Europe PMC PMID:14760634 Europe PMC PMID:15172721 Europe PMC PMID:15906011 Europe PMC PMID:16705261 Europe PMC PMID:17451998 Europe PMC PMID:17733096 Europe PMC PMID:19064074 Europe PMC PMID:19850112 Europe PMC PMID:20314698 Europe PMC Reaxys:1098229 Reaxys UM-BBD_compID:c0132 UM-BBD METHANOL PDBeChem Methanol KEGG_COMPOUND methanol IUPAC methanol UniProt CH3OH ChEBI MeOH ChEBI Methyl alcohol KEGG_COMPOUND Methylalkohol NIST_Chemistry_WebBook carbinol ChemIDplus spirit of wood HMDB wood alcohol ChemIDplus wood naphtha ChemIDplus wood spirit NIST_Chemistry_WebBook A compound containing at least one carbon-halogen bond (where X is a halogen atom). 0 RX ** CHEBI:13444 CHEBI:36684 CHEBI:8767 KEGG:C01322 MetaCyc:Organohalogen-Compounds chebi_ontology RX organic halide organic halides organohalogen compounds CHEBI:17792 organohalogen compound CHEBI:17792 RX KEGG_COMPOUND RX UniProt organic halide KEGG_COMPOUND organic halides ChEBI organohalogen compounds ChEBI An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. 0 C3H7NO3 InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7) MTCFGRXMJLQNBG-UHFFFAOYSA-N 105.09262 105.04259 NC(CO)C(O)=O CHEBI:15081 CHEBI:26648 CHEBI:9116 Beilstein:1721402 CAS:302-84-1 Gmelin:26429 KEGG:C00716 KNApSAcK:C00001393 Reaxys:1721402 Wikipedia:Serine Serine serine chebi_ontology 2-Amino-3-hydroxypropionic acid 2-amino-3-hydroxypropanoic acid 3-Hydroxyalanine Serin CHEBI:17822 serine CHEBI:17822 Beilstein:1721402 Beilstein CAS:302-84-1 ChemIDplus CAS:302-84-1 KEGG COMPOUND CAS:302-84-1 NIST Chemistry WebBook Gmelin:26429 Gmelin Reaxys:1721402 Reaxys Serine KEGG_COMPOUND serine IUPAC 2-Amino-3-hydroxypropionic acid KEGG_COMPOUND 2-amino-3-hydroxypropanoic acid IUPAC 3-Hydroxyalanine KEGG_COMPOUND Serin ChEBI Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. CHEBI:14293 CHEBI:24206 CHEBI:24212 CHEBI:5306 CAS:1403-66-3 DrugBank:DB00798 KEGG:C00505 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside chebi_ontology Gentamicin gentamycins CHEBI:17833 gentamycin CHEBI:17833 CAS:1403-66-3 KEGG COMPOUND 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside IUPAC Gentamicin KEGG_COMPOUND gentamycins ChEBI A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms. 0 ClH HCl InChI=1S/ClH/h1H VEXZGXHMUGYJMC-UHFFFAOYSA-N 36.46064 35.97668 Cl[H] CHEBI:13364 CHEBI:24635 CHEBI:5590 CAS:7647-01-0 Drug_Central:4568 Gmelin:322 HMDB:HMDB0002306 KEGG:C01327 KEGG:D02057 MetaCyc:HCL PMID:15823700 PMID:17492841 PMID:22804993 Reaxys:1098214 Wikipedia:HCl Wikipedia:Hydrochloric_acid Hydrogen chloride chlorane chloridohydrogen hydrogen chloride chebi_ontology Chlorwasserstoff HCl Hydrochloride Hydrogenchlorid Wasserstoffchlorid [HCl] chlorure d'hydrogene cloruro de hidrogeno hydrochloric acid CHEBI:17883 hydrogen chloride CHEBI:17883 CAS:7647-01-0 ChemIDplus CAS:7647-01-0 KEGG COMPOUND CAS:7647-01-0 NIST Chemistry WebBook Drug_Central:4568 DrugCentral Gmelin:322 Gmelin PMID:15823700 Europe PMC PMID:17492841 Europe PMC PMID:22804993 Europe PMC Reaxys:1098214 Reaxys Hydrogen chloride KEGG_COMPOUND chlorane IUPAC chloridohydrogen IUPAC hydrogen chloride IUPAC Chlorwasserstoff ChEBI HCl KEGG_COMPOUND Hydrochloride KEGG_COMPOUND Hydrogenchlorid ChEBI Wasserstoffchlorid ChEBI [HCl] IUPAC chlorure d'hydrogene ChEBI cloruro de hidrogeno ChEBI hydrochloric acid ChemIDplus A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. CHEBI:14202 CHEBI:4697 KEGG:C01351 Donor chebi_ontology Donator donneur CHEBI:17891 donor CHEBI:17891 Donor KEGG_COMPOUND Donator ChEBI donneur ChEBI D-Glucopyranose having alpha-configuration at the anomeric centre. 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1 WQZGKKKJIJFFOK-DVKNGEFBSA-N 180.15588 180.06339 OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O CHEBI:10242 CHEBI:12318 CHEBI:22386 CHEBI:40557 CHEBI:42802 Beilstein:1281608 Beilstein:5730158 CAS:492-62-6 GlyGen:G58161NS GlyTouCan:G58161NS Gmelin:329225 KEGG:C00267 KNApSAcK:C00001122 PDBeChem:GLC PMID:19443021 PMID:25568069 PMID:31537530 ALPHA-D-GLUCOSE alpha-D-Glucose alpha-D-glucopyranose alpha-D-glucose chebi_ontology WURCS=2.0/1,1,0/[a2122h-1a_1-5]/1/ alpha-D-Glc alpha-dextrose CHEBI:17925 alpha-D-glucose CHEBI:17925 Beilstein:1281608 Beilstein Beilstein:5730158 Beilstein CAS:492-62-6 ChemIDplus CAS:492-62-6 KEGG COMPOUND CAS:492-62-6 NIST Chemistry WebBook Gmelin:329225 Gmelin PMID:19443021 Europe PMC PMID:25568069 Europe PMC PMID:31537530 Europe PMC ALPHA-D-GLUCOSE PDBeChem alpha-D-Glucose KEGG_COMPOUND alpha-D-glucopyranose IUPAC alpha-D-glucose UniProt WURCS=2.0/1,1,0/[a2122h-1a_1-5]/1/ GlyTouCan alpha-D-Glc ChEBI alpha-dextrose ChemIDplus A halide anion formed when chlorine picks up an electron to form an an anion. -1 Cl InChI=1S/ClH/h1H/p-1 VEXZGXHMUGYJMC-UHFFFAOYSA-M 35.45270 34.96940 [Cl-] CHEBI:13291 CHEBI:13970 CHEBI:3616 CHEBI:3731 CHEBI:48804 Beilstein:3587171 CAS:16887-00-6 FooDB:FDB006557 Gmelin:14910 HMDB:HMDB0000492 KEGG:C00698 MetaCyc:CL- PDBeChem:CL PMID:38280867 PMID:38573803 PMID:38604039 UM-BBD_compID:c0884 Wikipedia:Chloride Chloride chloride chloride(1-) chebi_ontology CHLORIDE ION Chloride ion Chloride(1-) Chlorine anion Cl(-) Cl- CHEBI:17996 chloride CHEBI:17996 Beilstein:3587171 Beilstein CAS:16887-00-6 ChemIDplus CAS:16887-00-6 KEGG COMPOUND CAS:16887-00-6 NIST Chemistry WebBook Gmelin:14910 Gmelin PMID:38280867 Europe PMC PMID:38573803 Europe PMC PMID:38604039 Europe PMC UM-BBD_compID:c0884 UM-BBD Chloride KEGG_COMPOUND chloride IUPAC chloride UniProt chloride(1-) IUPAC CHLORIDE ION PDBeChem Chloride ion KEGG_COMPOUND Chloride(1-) ChemIDplus Chlorine anion NIST_Chemistry_WebBook Cl(-) IUPAC Cl- KEGG_COMPOUND 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. CHEBI:14517 CHEBI:25054 CHEBI:6486 KEGG:C01356 Lipid lipids chebi_ontology CHEBI:18059 lipid CHEBI:18059 Lipid KEGG_COMPOUND lipids IUPAC Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose). CHEBI:14399 CHEBI:24590 CHEBI:5709 GlyGen:G70994MS GlyTouCan:G70994MS KEGG:C00738 Hexose chebi_ontology WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/ hexoses CHEBI:18133 hexose CHEBI:18133 Hexose KEGG_COMPOUND WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/ GlyTouCan hexoses ChEBI 0 HX 1.008 1.00783 *[H] CHEBI:13368 CHEBI:37140 CHEBI:5599 hydrogen halide hydrogen halides chebi_ontology hydrogen halides CHEBI:18140 hydrogen halide CHEBI:18140 hydrogen halide IUPAC hydrogen halides IUPAC hydrogen halides ChEBI A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues. CHEBI:14864 CHEBI:26205 CHEBI:8322 KEGG:C00420 Polysaccharide polysaccharides chebi_ontology Glycan Glycane Glykan Glykane glycans polisacarido polisacaridos CHEBI:18154 polysaccharide CHEBI:18154 Polysaccharide KEGG_COMPOUND polysaccharides IUPAC Glycan KEGG_COMPOUND Glycane ChEBI Glykan ChEBI Glykane ChEBI glycans IUPAC polisacarido ChEBI polisacaridos IUPAC A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. 0 C16H18N2O4S InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1 JGSARLDLIJGVTE-MBNYWOFBSA-N 334.392 334.09873 N12C([C@H]([C@]1(SC([C@@H]2C(O)=O)(C)C)[H])NC(CC3=CC=CC=C3)=O)=O CHEBI:14743 CHEBI:25866 CHEBI:45073 CHEBI:7962 Beilstein:44740 CAS:61-33-6 DrugBank:DB01053 Drug_Central:2082 Gmelin:781913 HMDB:HMDB0015186 KEGG:C05551 KEGG:D02336 LINCS:LSM-3229 PDBeChem:PNN PMID:10930630 PMID:11431418 PMID:11906332 PMID:12569987 PMID:12850488 PMID:1384868 PMID:16033609 PMID:1709917 PMID:2083978 PMID:24485692 PMID:24631718 PMID:25998949 PMID:27731424 PMID:29017833 PMID:29355985 PMID:6161899 PMID:7602118 PMID:7716788 Patent:US3024169 Reaxys:44740 Wikipedia:Benzylpenicillin 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylic acid Benzylpenicillin chebi_ontology (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-(2-phenylacetamido)penicillanic acid PCG PENICILLIN G PG Penicillin G bencilpenicilina bensylpenicillin benzyl benicillin benzylpenicillin benzylpenicilline benzylpenicillinic acid benzylpenicillinum free penicillin II CHEBI:18208 benzylpenicillin CHEBI:18208 Beilstein:44740 Beilstein CAS:61-33-6 ChemIDplus CAS:61-33-6 KEGG COMPOUND Drug_Central:2082 DrugCentral Gmelin:781913 Gmelin PMID:10930630 Europe PMC PMID:11431418 Europe PMC PMID:11906332 Europe PMC PMID:12569987 Europe PMC PMID:12850488 Europe PMC PMID:1384868 Europe PMC PMID:16033609 Europe PMC PMID:1709917 Europe PMC PMID:2083978 Europe PMC PMID:24485692 Europe PMC PMID:24631718 Europe PMC PMID:25998949 Europe PMC PMID:27731424 Europe PMC PMID:29017833 Europe PMC PMID:29355985 Europe PMC PMID:6161899 Europe PMC PMID:7602118 Europe PMC PMID:7716788 Europe PMC Reaxys:44740 Reaxys 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylic acid IUPAC Benzylpenicillin KEGG_COMPOUND (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ChEBI 6-(2-phenylacetamido)penicillanic acid ChemIDplus PCG ChEBI PENICILLIN G PDBeChem PG ChEBI Penicillin G KEGG_COMPOUND bencilpenicilina ChemIDplus bensylpenicillin ChEBI benzyl benicillin ChEBI benzylpenicillin KEGG_DRUG benzylpenicilline ChemIDplus benzylpenicillinic acid ChemIDplus benzylpenicillinum ChemIDplus free penicillin II ChemIDplus Any nucleoside where the sugar component is D-ribose. 0 C5H9O4R 133.123 133.05008 OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O CHEBI:13014 CHEBI:13015 CHEBI:13685 CHEBI:21085 CHEBI:26560 CHEBI:4240 CHEBI:8844 KEGG:C00911 Ribonucleoside chebi_ontology a ribonucleoside ribonucleosides CHEBI:18254 ribonucleoside CHEBI:18254 Ribonucleoside KEGG_COMPOUND a ribonucleoside UniProt ribonucleosides ChEBI An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5. 0 C5H12N2O2 InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9) AHLPHDHHMVZTML-UHFFFAOYSA-N 132.16106 132.08988 NCCCC(N)C(O)=O CHEBI:7784 Beilstein:1722296 CAS:616-07-9 Gmelin:847696 KEGG:C01602 KNApSAcK:C00001384 PMID:15449570 PMID:17190852 PMID:22264337 Reaxys:1722296 2,5-diaminopentanoic acid Ornithine ornithine chebi_ontology 2,5-Diaminopentanoic acid 2,5-Diaminovaleric acid DL-Ornithine Orn CHEBI:18257 ornithine CHEBI:18257 Beilstein:1722296 Beilstein CAS:616-07-9 ChemIDplus Gmelin:847696 Gmelin PMID:15449570 Europe PMC PMID:17190852 Europe PMC PMID:22264337 Europe PMC Reaxys:1722296 Reaxys 2,5-diaminopentanoic acid IUPAC Ornithine KEGG_COMPOUND ornithine IUPAC 2,5-Diaminopentanoic acid KEGG_COMPOUND 2,5-Diaminovaleric acid KEGG_COMPOUND DL-Ornithine ChemIDplus Orn IUPAC That part of DNA or RNA that may be involved in pairing. CHEBI:13873 CHEBI:25598 CHEBI:2995 KEGG:C00701 Wikipedia:Nucleobase chebi_ontology Base nucleobases CHEBI:18282 nucleobase CHEBI:18282 Base KEGG_COMPOUND nucleobases ChEBI 0 Mn InChI=1S/Mn PWHULOQIROXLJO-UHFFFAOYSA-N 54.93805 54.93804 [Mn] CHEBI:13382 CHEBI:25153 CHEBI:6681 CAS:7439-96-5 KEGG:C00034 WebElements:Mn manganese chebi_ontology 25Mn Mangan Manganese Mn manganese manganeso manganum CHEBI:18291 manganese atom CHEBI:18291 CAS:7439-96-5 ChemIDplus CAS:7439-96-5 KEGG COMPOUND manganese IUPAC 25Mn IUPAC Mangan NIST_Chemistry_WebBook Manganese KEGG_COMPOUND Mn IUPAC Mn UniProt manganese ChEBI manganeso ChEBI manganum ChEBI An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms. 0 CH3R 15.035 15.02348 C[*] CHEBI:13435 CHEBI:22317 CHEBI:2576 KEGG:C01371 Alkane alkane alkanes chebi_ontology Alkan RH alcane alcanes alcano alcanos an alkane CHEBI:18310 alkane CHEBI:18310 Alkane KEGG_COMPOUND alkane IUPAC alkanes IUPAC Alkan ChEBI RH KEGG_COMPOUND alcane IUPAC alcanes IUPAC alcano IUPAC alcanos IUPAC an alkane UniProt The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. 0 C4H10O2S2 InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2 VHJLVAABSRFDPM-UHFFFAOYSA-N 154.25100 154.01222 OC(CS)C(O)CS CHEBI:11174 CHEBI:23854 CHEBI:4664 Beilstein:8144556 CAS:3483-12-3 DrugBank:DB04447 KEGG:C00265 LINCS:LSM-36870 PMID:16901854 PMID:18022205 PMID:23673948 PMID:24124079 PMID:7592847 1,4-Dithiothreitol 1,4-dithiothreitol rel-(2R,3R)-1,4-disulfanylbutane-2,3-diol chebi_ontology (R*,R*)-1,4-dimercapto-2,3-butanediol Cleland's reagent DL-threo-1,4-Dimercapto-2,3-butanediol DTL DTT Dithiothreitol Dithiotreitol rac-Dithiothreitol threo-1,4-Dimercapto-2,3-butanediol CHEBI:18320 1,4-dithiothreitol CHEBI:18320 Beilstein:8144556 Beilstein CAS:3483-12-3 ChemIDplus CAS:3483-12-3 KEGG COMPOUND CAS:3483-12-3 NIST Chemistry WebBook PMID:16901854 Europe PMC PMID:18022205 Europe PMC PMID:23673948 Europe PMC PMID:24124079 Europe PMC PMID:7592847 Europe PMC 1,4-Dithiothreitol KEGG_COMPOUND 1,4-dithiothreitol UniProt rel-(2R,3R)-1,4-disulfanylbutane-2,3-diol IUPAC (R*,R*)-1,4-dimercapto-2,3-butanediol NIST_Chemistry_WebBook Cleland's reagent NIST_Chemistry_WebBook DL-threo-1,4-Dimercapto-2,3-butanediol ChemIDplus DTL ChEBI DTT ChEBI Dithiothreitol KEGG_COMPOUND Dithiotreitol ChemIDplus rac-Dithiothreitol ChemIDplus threo-1,4-Dimercapto-2,3-butanediol KEGG_COMPOUND A phosphate ion that is the conjugate base of hydrogenphosphate. -3 O4P InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3 NBIIXXVUZAFLBC-UHFFFAOYSA-K 94.97136 94.95507 [O-]P([O-])([O-])=O CHEBI:14791 CHEBI:45024 CHEBI:7793 Beilstein:3903772 CAS:14265-44-2 Gmelin:1997 KEGG:C00009 PDBeChem:PO4 Reaxys:3903772 Wikipedia:Phosphate phosphate tetraoxidophosphate(3-) tetraoxophosphate(3-) tetraoxophosphate(V) chebi_ontology Orthophosphate PHOSPHATE ION PO4(3-) Phosphate [PO4](3-) CHEBI:18367 phosphate(3-) CHEBI:18367 Beilstein:3903772 Beilstein CAS:14265-44-2 ChemIDplus CAS:14265-44-2 KEGG COMPOUND Gmelin:1997 Gmelin PDBeChem:PO4 ChEBI Reaxys:3903772 Reaxys phosphate IUPAC tetraoxidophosphate(3-) IUPAC tetraoxophosphate(3-) IUPAC tetraoxophosphate(V) IUPAC Orthophosphate KEGG_COMPOUND PHOSPHATE ION PDBeChem PO4(3-) IUPAC Phosphate KEGG_COMPOUND [PO4](3-) IUPAC A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate. 0 C5H7O5PR2 178.07980 178.00311 OP1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1 CHEBI:1331 CHEBI:14672 CHEBI:19833 chebi_ontology nucleoside 3',5'-cyclic phosphates CHEBI:18375 nucleoside 3',5'-cyclic phosphate CHEBI:18375 nucleoside 3',5'-cyclic phosphates ChEBI A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it. 0 CNR 26.01740 26.00307 [*]C#N CHEBI:13212 CHEBI:13426 CHEBI:13660 CHEBI:25547 CHEBI:7584 KEGG:C00726 Nitrile nitrile nitriles chebi_ontology Nitril R-CN a nitrile nitrilos CHEBI:18379 nitrile CHEBI:18379 Nitrile KEGG_COMPOUND nitrile IUPAC nitriles IUPAC Nitril ChEBI R-CN KEGG_COMPOUND a nitrile UniProt nitrilos IUPAC A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom 0 CHN InChI=1S/CHN/c1-2/h1H LELOWRISYMNNSU-UHFFFAOYSA-N 27.02530 27.01090 C#N CHEBI:13362 CHEBI:5786 CAS:74-90-8 HMDB:HMDB0060292 KEGG:C01326 KNApSAcK:C00007569 MetaCyc:HCN PMID:19849830 PMID:26700190 PMID:26778429 PMID:26823582 PMID:26940198 PMID:27123778 Reaxys:1718793 Wikipedia:Hydrogen_cyanide Hydrogen cyanide hydridonitridocarbon hydrogen cyanide hydrogen(nitridocarbonate) methanenitrile chebi_ontology Blausaeure Cyanwasserstoff HCN [CHN] formonitrile hydrocyanic acid CHEBI:18407 hydrogen cyanide CHEBI:18407 CAS:74-90-8 ChemIDplus CAS:74-90-8 KEGG COMPOUND CAS:74-90-8 NIST Chemistry WebBook PMID:19849830 Europe PMC PMID:26700190 Europe PMC PMID:26778429 Europe PMC PMID:26823582 Europe PMC PMID:26940198 Europe PMC PMID:27123778 Europe PMC Reaxys:1718793 Reaxys Hydrogen cyanide KEGG_COMPOUND hydridonitridocarbon IUPAC hydrogen cyanide IUPAC hydrogen cyanide UniProt hydrogen(nitridocarbonate) IUPAC methanenitrile IUPAC Blausaeure ChEBI Cyanwasserstoff NIST_Chemistry_WebBook HCN KEGG_COMPOUND [CHN] IUPAC formonitrile IUPAC hydrocyanic acid NIST_Chemistry_WebBook A guanidinium ion obtained by protonation of both guanidino groups of streptidine; major species at pH 7.3. +2 C8H20N6O4 InChI=1S/C8H18N6O4/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14)/p+2/t1-,2+,3-,4+,5-,6- MSXMXWJPFIDEMT-FAEUDGQSSA-P 264.285 264.15351 NC(=[NH2+])N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](NC(N)=[NH2+])[C@@H]1O {[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diimino}bis(aminomethaniminium) chebi_ontology streptidine streptidine dication {[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diazanediyl}bis(aminomethaniminium) CHEBI:184376 streptidine(2+) CHEBI:184376 {[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diimino}bis(aminomethaniminium) IUPAC streptidine UniProt streptidine dication ChEBI {[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diazanediyl}bis(aminomethaniminium) IUPAC 0 C66H103N17O16S InChI=1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35-,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48-,52-,53-,54-/m0/s1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 1422.710 1421.74894 [C@@H]1(C(N[C@H](CC=2C=CC=CC2)C(=O)N[C@H](C(N[C@@H](C(N[C@H](C(NCCCC[C@@H](C(N[C@@H](C(N1)=O)CCC[NH3+])=O)NC([C@@H](NC([C@H](NC([C@@H](NC([C@H]3N=C(SC3)[C@H]([C@H](CC)C)[NH3+])=O)CC(C)C)=O)CCC([O-])=O)=O)[C@@H](C)CC)=O)=O)CC(N)=O)=O)CC(=O)[O-])=O)CC4=CNC=N4)=O)[C@@H](C)CC MetaCyc:CPD-19353 chebi_ontology bacitracin A CHEBI:184381 bacitracin A zwitterion CHEBI:184381 MetaCyc:CPD-19353 SUBMITTER bacitracin A UniProt A lactone having a six-membered lactone ring. delta-lactone chebi_ontology 1,5-lactone 1,5-lactones delta-lactona delta-lactonas delta-lactones CHEBI:18946 delta-lactone CHEBI:18946 delta-lactone ChEBI 1,5-lactone ChEBI 1,5-lactones ChEBI delta-lactona ChEBI delta-lactonas ChEBI delta-lactones ChEBI A potassium salt that lacks C-H bonds chebi_ontology CHEBI:190303 inorganic potassium salt CHEBI:190303 Zwitterionic form of imipenem having an anionic carboxy group and a protonated methaneimidamido group; major species at pH 7.3. 0 C12H17N3O4S InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 ZSKVGTPCRGIANV-ZXFLCMHBSA-N 299.350 299.09398 [H]C(=[NH2+])NCCSC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])C1)C([O-])=O (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminiomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate chebi_ontology imipenem CHEBI:190509 imipenem zwitterion CHEBI:190509 (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminiomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate IUPAC imipenem UniProt chebi_ontology 11alpha-hydroxy steroids CHEBI:19129 11alpha-hydroxy steroid CHEBI:19129 11alpha-hydroxy steroids ChEBI A zwitterion formed from ciprofloxacin by transfer of a proton from the carboxy to the amino group; major species at pH 7.3. 0 C17H18FN3O3 InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24) MYSWGUAQZAJSOK-UHFFFAOYSA-N 331.347 331.13322 [O-]C(=O)C1=CN(C2CC2)C2=CC(N3CC[NH2+]CC3)=C(F)C=C2C1=O MetaCyc:CPD-12843 PMID:11202360 PMID:12084502 PMID:21368411 PMID:9303400 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydroquinoline-3-carboxylate chebi_ontology CHEBI:192484 ciprofloxacin zwitterion CHEBI:192484 PMID:11202360 SUBMITTER PMID:12084502 SUBMITTER PMID:21368411 Europe PMC PMID:9303400 SUBMITTER 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydroquinoline-3-carboxylate IUPAC A secondary ammonium ion that is the conjugate acid of ciprofloxacin resulting from the protonation of the NH group; major species at acidic pH. +1 C17H19FN3O3 InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)/p+1 MYSWGUAQZAJSOK-UHFFFAOYSA-O 332.355 332.14050 OC(=O)C1=CN(C2CC2)C2=CC(N3CC[NH2+]CC3)=C(F)C=C2C1=O PMID:35371545 4-(3-carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)piperazin-1-ium chebi_ontology ciprofloxacin cation CHEBI:192486 ciprofloxacin(1+) CHEBI:192486 PMID:35371545 Europe PMC 4-(3-carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)piperazin-1-ium IUPAC ciprofloxacin cation ChEBI 0 C47H75NO16 InChI=1S/C47H75NO16/c1-28-18-15-13-11-9-7-5-6-8-10-12-14-16-21-36(63-46-44(57)41(48)43(56)31(4)62-46)25-38-40(45(58)59)37(53)27-47(60,64-38)26-33(50)20-17-19-32(49)22-34(51)23-35(52)24-39(54)61-30(3)29(2)42(28)55/h5-6,8,10-16,18,21,28-38,40-44,46,49-53,55-57,60H,7,9,17,19-20,22-27,48H2,1-4H3,(H,58,59)/b6-5+,10-8+,13-11+,14-12+,18-15+,21-16+/t28-,29-,30-,31+,32+,33-,34+,35+,36-,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 RALQCAVZSAUESR-XTEMEEEFSA-N 910.108 909.50859 [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CCC[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 CAS:65086-32-0 PMID:15504830 (1R,3S,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,7,9,11,17,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid nystatin A2 chebi_ontology CHEBI:192979 nystatin A2 CHEBI:192979 CAS:65086-32-0 ChemIDplus PMID:15504830 Europe PMC (1R,3S,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,7,9,11,17,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid IUPAC nystatin A2 ChemIDplus An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively. 0 C18H20FN3O4 InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25) GSDSWSVVBLHKDQ-UHFFFAOYSA-N 361.373 361.14378 CC1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=O 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid chebi_ontology CHEBI:194135 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid CHEBI:194135 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid IUPAC chebi_ontology 3',5'-cyclic purine nucleotides CHEBI:19834 3',5'-cyclic purine nucleotide CHEBI:19834 3',5'-cyclic purine nucleotides ChEBI A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups. 0 C16H17N5O7S2 InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1 GPRBEKHLDVQUJE-QSWIMTSFSA-N 455.46500 455.05694 [H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O CHEBI:112504 CHEBI:3497 CHEBI:41475 Beilstein:1096643 CAS:63527-52-6 DrugBank:DB00493 Drug_Central:546 KEGG:C06885 KEGG:D07647 PDBeChem:CE3 PMID:10866367 PMID:11034276 PMID:11061623 PMID:11677129 PMID:12833570 PMID:1384868 PMID:14512220 PMID:1502708 PMID:15164972 PMID:15361989 PMID:15969234 PMID:1635063 PMID:17006042 PMID:17386217 PMID:18611527 PMID:19741292 PMID:21425867 PMID:24038683 PMID:24211456 PMID:29017833 PMID:9131470 Patent:DE2556736 Patent:DE2702501 Patent:US4098888 Patent:US4152432 Reaxys:1096643 Wikipedia:Cefotaxime 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cephotaxime cefotaxima cefotaxime cefotaximum CHEBI:204928 cefotaxime CHEBI:204928 Beilstein:1096643 Beilstein CAS:63527-52-6 ChemIDplus CAS:63527-52-6 DrugBank CAS:63527-52-6 KEGG COMPOUND CAS:63527-52-6 KEGG DRUG Drug_Central:546 DrugCentral PMID:10866367 ChEMBL PMID:11034276 Europe PMC PMID:11061623 Europe PMC PMID:11677129 ChEMBL PMID:12833570 Europe PMC PMID:1384868 Europe PMC PMID:14512220 Europe PMC PMID:1502708 Europe PMC PMID:15164972 Europe PMC PMID:15361989 Europe PMC PMID:15969234 Europe PMC PMID:1635063 ChEMBL PMID:17006042 Europe PMC PMID:17386217 Europe PMC PMID:18611527 Europe PMC PMID:19741292 Europe PMC PMID:21425867 Europe PMC PMID:24038683 Europe PMC PMID:24211456 Europe PMC PMID:29017833 Europe PMC PMID:9131470 Europe PMC Reaxys:1096643 Reaxys 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid IUPAC (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ChEMBL (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ChEMBL Cephotaxime ChemIDplus cefotaxima ChemIDplus cefotaxime KEGG_DRUG cefotaximum ChemIDplus A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase. chebi_ontology CHEBI:20854 ATP synthase inhibitor CHEBI:20854 A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase. 0 C16H17N3O7S2 InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1 WZOZEZRFJCJXNZ-ZBFHGGJFSA-N 427.45200 427.05079 [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O CHEBI:3500 CHEBI:41436 CHEBI:471714 CHEBI:658070 Beilstein:4216947 CAS:35607-66-0 DrugBank:DB01331 Drug_Central:550 HMDB:HMDB0015426 KEGG:C06887 KEGG:D02345 LINCS:LSM-5786 PDBeChem:CFX PMID:12569987 PMID:17043131 PMID:17178800 PMID:17220412 PMID:17353248 PMID:17387156 PMID:17923492 PMID:18056283 PMID:18070972 PMID:2083978 PMID:29017833 PMID:8360877 Patent:DE2129675 Patent:DE2203653 Patent:US4297488 Reaxys:4216947 Wikipedia:Cefoxitin (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid Cefoxitin chebi_ontology (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CFX Cephoxitin Rephoxitin cefoxitin cefoxitina cefoxitine cefoxitinum ceftoxitin CHEBI:209807 cefoxitin CHEBI:209807 Beilstein:4216947 Beilstein CAS:35607-66-0 ChemIDplus CAS:35607-66-0 KEGG COMPOUND Drug_Central:550 DrugCentral PMID:12569987 Europe PMC PMID:17043131 ChEMBL PMID:17178800 ChEMBL PMID:17220412 ChEMBL PMID:17353248 ChEMBL PMID:17387156 ChEMBL PMID:17923492 ChEMBL PMID:18056283 ChEMBL PMID:18070972 ChEMBL PMID:2083978 Europe PMC PMID:29017833 Europe PMC PMID:8360877 ChEMBL Reaxys:4216947 Reaxys (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid IUPAC Cefoxitin ChemIDplus (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC CFX KEGG_DRUG Cephoxitin ChemIDplus Rephoxitin ChemIDplus cefoxitin KEGG_DRUG cefoxitina ChemIDplus cefoxitine ChemIDplus cefoxitinum ChemIDplus ceftoxitin ChemIDplus N-acylglucosamine chebi_ontology N-acylglucosamines CHEBI:21638 N-acylglucosamine CHEBI:21638 N-acylglucosamine ChEBI N-acylglucosamines ChEBI N-acyl-hexosamine chebi_ontology N-acyl-hexosamines CHEBI:21656 N-acyl-hexosamine CHEBI:21656 N-acyl-hexosamine ChEBI N-acyl-hexosamines ChEBI A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. glycosylamine chebi_ontology N-glycoside N-glycosides N-glycosyl compounds glycosylamines CHEBI:21731 N-glycosyl compound CHEBI:21731 glycosylamine IUPAC N-glycoside ChEBI N-glycosides ChEBI N-glycosyl compounds ChEBI glycosylamines IUPAC A substance used to destroy pests of the subclass Acari (mites and ticks). Wikipedia:Acaricide chebi_ontology Akarizid Akarizide acaricides miticide CHEBI:22153 acaricide CHEBI:22153 Akarizid ChEBI Akarizide ChEBI acaricides ChEBI miticide ChEBI Compounds with the general formula RNHC(=O)CH3. chebi_ontology CHEBI:22160 acetamides CHEBI:22160 An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids. acyl group alkanoyl chebi_ontology acyl groups alkanoyl group groupe acyle CHEBI:22221 acyl group CHEBI:22221 acyl group IUPAC alkanoyl IUPAC acyl groups ChEBI alkanoyl group ChEBI groupe acyle IUPAC alkali metals chebi_ontology Alkalimetall Alkalimetalle alkali metal metal alcalin metal alcalino metales alcalinos metaux alcalins CHEBI:22314 alkali metal atom CHEBI:22314 alkali metals IUPAC Alkalimetall ChEBI Alkalimetalle ChEBI alkali metal ChEBI metal alcalin ChEBI metal alcalino ChEBI metales alcalinos ChEBI metaux alcalins ChEBI Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. Wikipedia:Alkaloid Alkaloid alkaloids chebi_ontology Alkaloide alcaloide alcaloides CHEBI:22315 alkaloid CHEBI:22315 Alkaloid ChEBI alkaloids IUPAC Alkaloide ChEBI alcaloide ChEBI alcaloides ChEBI A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom. alkyl group alkyl groups chebi_ontology groupe alkyle grupo alquilo grupos alquilo CHEBI:22323 alkyl group CHEBI:22323 alkyl group IUPAC alkyl groups IUPAC groupe alkyle IUPAC grupo alquilo IUPAC grupos alquilo IUPAC alpha-D-glucoside chebi_ontology alpha-D-glucosides an alpha-D-glucoside CHEBI:22390 alpha-D-glucoside CHEBI:22390 alpha-D-glucoside ChEBI alpha-D-glucosides ChEBI an alpha-D-glucoside UniProt An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group. chebi_ontology amino alcohols aminoalcohol aminoalcohols CHEBI:22478 amino alcohol CHEBI:22478 amino alcohols ChEBI aminoalcohol ChEBI aminoalcohols ChEBI amino cyclitol glycoside chebi_ontology amino cyclitol glycosides CHEBI:22479 amino cyclitol glycoside CHEBI:22479 amino cyclitol glycoside ChEBI amino cyclitol glycosides ChEBI chebi_ontology aminobenzoates CHEBI:22494 aminobenzoate CHEBI:22494 aminobenzoates ChEBI 0 C7H7NO2 137.136 137.04768 aminobenzoic acid chebi_ontology Aminobenzoesaeure CHEBI:22495 aminobenzoic acid CHEBI:22495 aminobenzoic acid IUPAC Aminobenzoesaeure ChEBI chebi_ontology aminoglycans CHEBI:22506 aminoglycan CHEBI:22506 aminoglycans ChEBI chebi_ontology aminoglycoside antibiotics CHEBI:22507 aminoglycoside antibiotic CHEBI:22507 aminoglycoside antibiotics ChEBI Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives. chebi_ontology CHEBI:22562 anilines CHEBI:22562 A monoatomic or polyatomic species having one or more elementary charges of the electron. Anion anion chebi_ontology Anionen aniones anions CHEBI:22563 anion CHEBI:22563 Anion ChEBI anion ChEBI anion IUPAC Anionen ChEBI aniones ChEBI anions IUPAC A class of macrocyclic lactams that consist of an aromatic (phenyl or naphthyl) or quinonoid (benzoquinone or naphthoquinone) moiety that is bridged by an aliphatic chain. Wikipedia:Ansamycin chebi_ontology CHEBI:22565 ansamycin CHEBI:22565 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. chebi_ontology antioxidants antioxydant antoxidant CHEBI:22586 antioxidant CHEBI:22586 antioxidants ChEBI antioxydant ChEBI antoxidant ChEBI A substance that destroys or inhibits replication of viruses. chebi_ontology anti-viral agent anti-viral agents antiviral antiviral agents antivirals CHEBI:22587 antiviral agent CHEBI:22587 anti-viral agent ChEBI anti-viral agents ChEBI antiviral ChEBI antiviral agents ChEBI antivirals ChEBI arabinoside chebi_ontology arabinosides CHEBI:22601 arabinoside CHEBI:22601 arabinoside ChEBI arabinosides ChEBI A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system. chebi_ontology arenecarboxamides CHEBI:22645 arenecarboxamide CHEBI:22645 arenecarboxamides ChEBI A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). KEGG:C00701 Base base chebi_ontology Base1 Base2 Basen Nucleobase bases CHEBI:22695 base CHEBI:22695 Base ChEBI base ChEBI base IUPAC Base1 KEGG_COMPOUND Base2 KEGG_COMPOUND Basen ChEBI Nucleobase KEGG_COMPOUND bases ChEBI chebi_ontology CHEBI:22702 benzamides CHEBI:22702 Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. chebi_ontology CHEBI:22712 benzenes CHEBI:22712 chebi_ontology arenesulfonates CHEBI:22713 arenesulfonate oxoanion CHEBI:22713 arenesulfonates ChEBI An organic heterocyclic compound containing a benzene ring fused to an imidazole ring. chebi_ontology CHEBI:22715 benzimidazoles CHEBI:22715 A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid. chebi_ontology benzoate anion CHEBI:22718 benzoates CHEBI:22718 benzoate anion ChEBI Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group. chebi_ontology CHEBI:22723 benzoic acids CHEBI:22723 Wikipedia:Benzopyran chebi_ontology benzopyrans CHEBI:22727 benzopyran CHEBI:22727 benzopyrans ChEBI chebi_ontology benzopyrroles CHEBI:22728 benzopyrrole CHEBI:22728 benzopyrroles ChEBI Any compound that produces a peak used to reference an NMR spectrum during data pre-processing. chebi_ontology NMR chemical shift reference compounds NMR chemical shift standard NMR chemical shift standards NMR internal standard NMR internal standards NMR reference standard NMR reference standards CHEBI:228364 NMR chemical shift reference compound CHEBI:228364 NMR chemical shift reference compounds ChEBI NMR chemical shift standard ChEBI NMR chemical shift standards ChEBI NMR internal standard ChEBI NMR internal standards ChEBI NMR reference standard ChEBI NMR reference standards ChEBI Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond. chebi_ontology CHEBI:22888 biphenyls CHEBI:22888 A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2. CHEBI:584977 DrugBank:DB00290 Wikipedia:Bleomycin chebi_ontology CHEBI:22907 bleomycin CHEBI:22907 An insecticide compound naturally occurring in plants. chebi_ontology botanical insecticide botanical insecticides phytogenic insecticides CHEBI:22917 phytogenic insecticide CHEBI:22917 botanical insecticide ChEBI botanical insecticides ChEBI phytogenic insecticides ChEBI A diol that is a butanediol or a derivative of a butanediol. chebi_ontology CHEBI:22944 butanediols CHEBI:22944 A monocarboxylic acid anion that is the conjugate base of sulbactam resulting from the deprotonation of the carboxy group; Major species at pH 7.3. -1 C8H10NO5S InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/p-1/t5-,6+/m1/s1 FKENQMMABCRJMK-RITPCOANSA-M 232.230 232.02852 [H][C@@]12CC(=O)N1[C@@H](C([O-])=O)C(C)(C)S2(=O)=O (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide chebi_ontology sulbactam anion CHEBI:229543 sulbactam(1-) CHEBI:229543 (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide IUPAC sulbactam anion ChEBI chebi_ontology calcium ionophores CHEBI:22986 calcium ionophore CHEBI:22986 calcium ionophores ChEBI Any ester of carbamic acid or its N-substituted derivatives. Wikipedia:Carbamate chebi_ontology carbamate esters carbamates CHEBI:23003 carbamate ester CHEBI:23003 carbamate esters ChEBI carbamates ChEBI The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid. 0 CH2NO 44.03272 44.01364 *C(N)=O PMID:24168430 carbamoyl chebi_ontology -C(O)NH2 -CONH2 aminocarbonyl carbamyl carbamyl group carboxamide CHEBI:23004 carbamoyl group CHEBI:23004 PMID:24168430 Europe PMC carbamoyl IUPAC -C(O)NH2 ChEBI -CONH2 IUPAC aminocarbonyl IUPAC carbamyl ChEBI carbamyl group ChEBI carboxamide IUPAC Any carbohydrate derivative that exhibits antibiotic activity. chebi_ontology CHEBI:23007 carbohydrate-containing antibiotic CHEBI:23007 An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule. Wikipedia:Carbonic_anhydrase_inhibitor chebi_ontology EC 4.2.1.1 (carbonic anhydrase) inhibitors EC 4.2.1.1 inhibitor EC 4.2.1.1 inhibitors anhydrase inhibitor anhydrase inhibitors carbonate anhydrase inhibitor carbonate anhydrase inhibitors carbonate dehydratase inhibitor carbonate dehydratase inhibitors carbonate hydro-lyase (carbon-dioxide-forming) inhibitor carbonate hydro-lyase (carbon-dioxide-forming) inhibitors carbonate hydro-lyase inhibitor carbonate hydro-lyase inhibitors carbonic acid anhydrase inhibitor carbonic acid anhydrase inhibitors carbonic anhydrase (EC 4.2.1.1) inhibitor carbonic anhydrase (EC 4.2.1.1) inhibitors carbonic anhydrase A inhibitor carbonic anhydrase A inhibitors carbonic anhydrase inhibitor carbonic anhydrase inhibitors carboxyanhydrase inhibitor carboxyanhydrase inhibitors CHEBI:23018 EC 4.2.1.1 (carbonic anhydrase) inhibitor CHEBI:23018 EC 4.2.1.1 (carbonic anhydrase) inhibitors ChEBI EC 4.2.1.1 inhibitor ChEBI EC 4.2.1.1 inhibitors ChEBI anhydrase inhibitor ChEBI anhydrase inhibitors ChEBI carbonate anhydrase inhibitor ChEBI carbonate anhydrase inhibitors ChEBI carbonate dehydratase inhibitor ChEBI carbonate dehydratase inhibitors ChEBI carbonate hydro-lyase (carbon-dioxide-forming) inhibitor ChEBI carbonate hydro-lyase (carbon-dioxide-forming) inhibitors ChEBI carbonate hydro-lyase inhibitor ChEBI carbonate hydro-lyase inhibitors ChEBI carbonic acid anhydrase inhibitor ChEBI carbonic acid anhydrase inhibitors ChEBI carbonic anhydrase (EC 4.2.1.1) inhibitor ChEBI carbonic anhydrase (EC 4.2.1.1) inhibitors ChEBI carbonic anhydrase A inhibitor ChEBI carbonic anhydrase A inhibitors ChEBI carbonic anhydrase inhibitor ChEBI carbonic anhydrase inhibitors ChEBI carboxyanhydrase inhibitor ChEBI carboxyanhydrase inhibitors ChEBI 0 CO 28.01010 27.99491 O=C(*)* carbonyl carbonyl group chebi_ontology >C=O CHEBI:23019 carbonyl group CHEBI:23019 carbonyl IUPAC carbonyl group ChEBI carbonyl group UniProt >C=O IUPAC A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-beta-glucan synthase (EC 2.4.1.34). Wikipedia:1,3-Beta-glucan_synthase chebi_ontology (1,3)-beta-glucan (callose) synthase inhibitor (1,3)-beta-glucan (callose) synthase inhibitors 1,3-beta-D-glucan synthase inhibitor 1,3-beta-D-glucan synthase inhibitors 1,3-beta-D-glucan synthetase inhibitor 1,3-beta-D-glucan synthetase inhibitors 1,3-beta-D-glucan--UDP glucosyltransferase inhibitor 1,3-beta-D-glucan--UDP glucosyltransferase inhibitors 1,3-beta-D-glucan-UDP glucosyltransferase inhibitor 1,3-beta-D-glucan-UDP glucosyltransferase inhibitors 1,3-beta-glucan synthase inhibitor 1,3-beta-glucan synthase inhibitors 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitor 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitors EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitors EC 2.4.1.34 inhibitor EC 2.4.1.34 inhibitors GS-II inhibitor GS-II inhibitors UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitor UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitors UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitor UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitors UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitor UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitors UDP-glucose-beta-glucan glucosyltransferase inhibitor UDP-glucose-beta-glucan glucosyltransferase inhibitors UDP-glucose:(1,3)beta-glucan synthase inhibitor UDP-glucose:(1,3)beta-glucan synthase inhibitors UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitor UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitors beta-1,3-glucan synthase inhibitor beta-1,3-glucan synthase inhibitors beta-1,3-glucan synthetase inhibitor beta-1,3-glucan synthetase inhibitors callose synthase inhibitor callose synthase inhibitors callose synthetase inhibitor callose synthetase inhibitors paramylon synthetase inhibitor paramylon synthetase inhibitors uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitor uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitors CHEBI:230471 EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor CHEBI:230471 (1,3)-beta-glucan (callose) synthase inhibitor ChEBI (1,3)-beta-glucan (callose) synthase inhibitors ChEBI 1,3-beta-D-glucan synthase inhibitor ChEBI 1,3-beta-D-glucan synthase inhibitors ChEBI 1,3-beta-D-glucan synthetase inhibitor ChEBI 1,3-beta-D-glucan synthetase inhibitors ChEBI 1,3-beta-D-glucan--UDP glucosyltransferase inhibitor ChEBI 1,3-beta-D-glucan--UDP glucosyltransferase inhibitors ChEBI 1,3-beta-D-glucan-UDP glucosyltransferase inhibitor ChEBI 1,3-beta-D-glucan-UDP glucosyltransferase inhibitors ChEBI 1,3-beta-glucan synthase inhibitor ChEBI 1,3-beta-glucan synthase inhibitors ChEBI 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitor ChEBI 1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitors ChEBI EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitors ChEBI EC 2.4.1.34 inhibitor ChEBI EC 2.4.1.34 inhibitors ChEBI GS-II inhibitor ChEBI GS-II inhibitors ChEBI UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitor ChEBI UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitors ChEBI UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitor ChEBI UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitors ChEBI UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitor ChEBI UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitors ChEBI UDP-glucose-beta-glucan glucosyltransferase inhibitor ChEBI UDP-glucose-beta-glucan glucosyltransferase inhibitors ChEBI UDP-glucose:(1,3)beta-glucan synthase inhibitor ChEBI UDP-glucose:(1,3)beta-glucan synthase inhibitors ChEBI UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitor ChEBI UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitors ChEBI beta-1,3-glucan synthase inhibitor ChEBI beta-1,3-glucan synthase inhibitors ChEBI beta-1,3-glucan synthetase inhibitor ChEBI beta-1,3-glucan synthetase inhibitors ChEBI callose synthase inhibitor ChEBI callose synthase inhibitors ChEBI callose synthetase inhibitor ChEBI callose synthetase inhibitors ChEBI paramylon synthetase inhibitor ChEBI paramylon synthetase inhibitors ChEBI uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitor ChEBI uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitors ChEBI A class of beta-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring. Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy. 0 C7H5NO3SR2 183.18500 182.99901 [H][C@]12SCC([*])=C(N1C(=O)[C@H]2[*])C(O)=O CHEBI:3538 KEGG:C00875 PMID:10069359 PMID:11936371 PMID:12833570 PMID:24269048 PMID:3320614 PMID:6762896 PMID:8426246 Wikipedia:Cephalosporin Cephalosporin chebi_ontology cephalosphorin cephalosphorins cephalosporins CHEBI:23066 cephalosporin CHEBI:23066 PMID:10069359 Europe PMC PMID:11936371 Europe PMC PMID:12833570 Europe PMC PMID:24269048 Europe PMC PMID:3320614 Europe PMC PMID:6762896 Europe PMC PMID:8426246 Europe PMC Cephalosporin KEGG_COMPOUND cephalosphorin ChEBI cephalosphorins ChEBI cephalosporins ChEBI chebi_ontology CHEBI:23089 chelate-forming peptide CHEBI:23089 chebi_ontology chloride salts chlorides CHEBI:23114 chloride salt CHEBI:23114 chloride salts ChEBI chlorides ChEBI 0 Cl InChI=1S/Cl ZAMOUSCENKQFHK-UHFFFAOYSA-N 35.45270 34.96885 [Cl] WebElements:Cl chlorine chebi_ontology 17Cl Chlor Cl chlore chlorine chlorum cloro CHEBI:23116 chlorine atom CHEBI:23116 chlorine IUPAC 17Cl IUPAC Chlor ChEBI Cl IUPAC chlore ChEBI chlorine ChEBI chlorum ChEBI cloro ChEBI A halogen molecular entity containing one or more atoms of chlorine. chebi_ontology CHEBI:23117 chlorine molecular entity CHEBI:23117 Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines. chebi_ontology CHEBI:23132 chlorobenzenes CHEBI:23132 A tertiary ammonium ion resulting from the protonation of the two amino groups of azithromycin; major species at pH 7.3. +2 C38H74N2O12 InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/p+2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 MQTOSJVFKKJCRP-BICOPXKESA-P 751.011 750.52308 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)[NH+](C)C)[C@](C)(O)C[C@@H](C)C[NH+](C)[C@H](C)[C@@H](O)[C@]1(C)O (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylazaniumyl)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azoniacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside chebi_ontology azithromycin dication CHEBI:231550 azithromycin(2+) CHEBI:231550 (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylazaniumyl)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azoniacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside IUPAC azithromycin dication ChEBI An oxo monocarboxylic acid anion that is the conjugate base of levofloxacin resulting from the deprotonation of the carboxy group; major species at pH 7.3. -1 C18H19FN3O4 InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/p-1/t10-/m0/s1 GSDSWSVVBLHKDQ-JTQLQIEISA-M 360.366 360.13651 C[C@H]1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C([O-])=O)C3=O (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate chebi_ontology levofloxacin anion CHEBI:231553 levofloxacin(1-) CHEBI:231553 (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate IUPAC levofloxacin anion ChEBI CHEBI:3666 chebi_ontology choline esters CHEBI:23213 choline ester CHEBI:23213 choline esters ChEBI A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof. chebi_ontology CHEBI:23217 cholines CHEBI:23217 chebi_ontology CHEBI:23232 chromenes CHEBI:23232 chebi_ontology CHEBI:23239 chromopeptide CHEBI:23239 An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). Wikipedia:Cofactor_(biochemistry) cofactor cofactors chebi_ontology CHEBI:23357 cofactor CHEBI:23357 cofactor IUPAC cofactors IUPAC chebi_ontology CHEBI:23366 compatible osmolytes CHEBI:23366 Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. molecular entity chebi_ontology entidad molecular entidades moleculares entite moleculaire molecular entities molekulare Entitaet CHEBI:23367 molecular entity CHEBI:23367 molecular entity IUPAC entidad molecular IUPAC entidades moleculares IUPAC entite moleculaire IUPAC molecular entities IUPAC molekulare Entitaet ChEBI copper molecular entity chebi_ontology copper compounds copper molecular entities CHEBI:23377 copper molecular entity CHEBI:23377 copper molecular entity ChEBI copper compounds ChEBI copper molecular entities ChEBI Cu 63.546 62.92960 copper cation chebi_ontology Cu cation copper cations CHEBI:23378 copper cation CHEBI:23378 copper cation IUPAC Cu cation UniProt copper cations ChEBI chebi_ontology CHEBI:23403 coumarins CHEBI:23403 A metal sulfate compound having copper(2+) as the metal ion. 0 CuO4S InChI=1S/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2 ARUVKPQLZAKDPS-UHFFFAOYSA-L 159.60960 158.88133 [Cu++].[O-]S([O-])(=O)=O CAS:7758-98-7 Gmelin:8294 KEGG:C18713 PMID:10469300 PMID:29079364 PMID:8566016 PPDB:178 Wikipedia:Copper(II)_sulfate Copper(II) sulfate copper(2+) sulfate copper(II) sulfate chebi_ontology CuSO4 Cupric sulfate copper sulfate cupric sulfate anhydrous CHEBI:23414 copper(II) sulfate CHEBI:23414 CAS:7758-98-7 ChemIDplus CAS:7758-98-7 KEGG COMPOUND Gmelin:8294 Gmelin PMID:10469300 Europe PMC PMID:29079364 Europe PMC PMID:8566016 Europe PMC Copper(II) sulfate KEGG_COMPOUND copper(2+) sulfate IUPAC copper(II) sulfate IUPAC CuSO4 IUPAC Cupric sulfate ChemIDplus copper sulfate ChemIDplus cupric sulfate anhydrous ChemIDplus Salts and C-organyl derivatives of hydrogen cyanide, HC#N. cyanides chebi_ontology CHEBI:23424 cyanides CHEBI:23424 cyanides IUPAC CHEBI:3990 cyclic amide chebi_ontology cyclic amides CHEBI:23443 cyclic amide CHEBI:23443 cyclic amide ChEBI cyclic amides ChEBI chebi_ontology cyclic nucleotides CHEBI:23447 cyclic nucleotide CHEBI:23447 cyclic nucleotides ChEBI chebi_ontology Cyclopeptid Zyklopeptid cyclic peptides peptide cyclique peptido ciclico CHEBI:23449 cyclic peptide CHEBI:23449 Cyclopeptid ChEBI Zyklopeptid ChEBI cyclic peptides ChEBI peptide cyclique IUPAC peptido ciclico IUPAC A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom. cyclitols chebi_ontology CHEBI:23451 cyclitol CHEBI:23451 cyclitols IUPAC A member of the class of oxazolidines that is isoxazoldin-3-one which is substituted at position 4 by an amino group. 0 C3H6N2O2 InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6) DYDCUQKUCUHJBH-UHFFFAOYSA-N 102.09190 102.04293 NC1CONC1=O CAS:68-39-3 KEGG:C06682 4-amino-1,2-oxazolidin-3-one chebi_ontology cycloserine CHEBI:23503 4-amino-1,2-oxazolidin-3-one CHEBI:23503 CAS:68-39-3 KEGG COMPOUND 4-amino-1,2-oxazolidin-3-one IUPAC cycloserine ChEBI chebi_ontology deoxyribonucleosides CHEBI:23636 deoxyribonucleoside CHEBI:23636 deoxyribonucleosides ChEBI A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually alpha-amino and alpha-hydroxy acids), commonly but not necessarily regularly alternating. depsipeptides chebi_ontology Depsipeptid CHEBI:23643 depsipeptide CHEBI:23643 depsipeptides IUPAC Depsipeptid ChEBI Any polyamine that contains two amino groups. diamines chebi_ontology CHEBI:23666 diamine CHEBI:23666 diamines IUPAC An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring. chebi_ontology diazoles CHEBI:23677 diazole CHEBI:23677 diazoles ChEBI Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions. dichlorobenzene chebi_ontology Dichlorbenzol dichlorobenzenes CHEBI:23697 dichlorobenzene CHEBI:23697 dichlorobenzene ChEBI dichlorobenzene IUPAC Dichlorbenzol ChEBI dichlorobenzenes ChEBI Any organic heteromonocyclic compound with a structure based on a dihydropyrrole. Wikipedia:Pyrroline pyrroline chebi_ontology dihydropyrrole pyrrolines CHEBI:23763 pyrroline CHEBI:23763 pyrroline ChemIDplus dihydropyrrole ChemIDplus pyrrolines ChEBI chebi_ontology quinolones CHEBI:23765 quinolone CHEBI:23765 quinolones ChEBI A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. Wikipedia:Diol diols chebi_ontology CHEBI:23824 diol CHEBI:23824 diols IUPAC Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). LIPID_MAPS_class:LMPR0104 diterpenoids chebi_ontology C20 isoprenoids diterpenoides CHEBI:23849 diterpenoid CHEBI:23849 LIPID_MAPS_class:LMPR0104 LIPID MAPS diterpenoids IUPAC C20 isoprenoids LIPID_MAPS diterpenoides ChEBI chebi_ontology dithiols CHEBI:23853 dithiol CHEBI:23853 dithiols ChEBI 0 C12H25 169.32690 169.19563 CCCCCCCCCCCC* dodecyl chebi_ontology CH3-[CH2]11- Dod dodecan-1-yl lauryl CHEBI:23870 dodecyl group CHEBI:23870 dodecyl IUPAC CH3-[CH2]11- IUPAC Dod CBN dodecan-1-yl ChEBI lauryl ChEBI -1 C12H25O4S InChI=1S/C12H26O4S/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H,13,14,15)/p-1 MOTZDAYCYVMXPC-UHFFFAOYSA-M 265.39050 265.14790 CCCCCCCCCCCCOS([O-])(=O)=O Beilstein:1820003 DrugBank:DB03967 Gmelin:336103 UM-BBD_compID:c0563 dodecyl sulfate chebi_ontology CHEBI:23872 dodecyl sulfate CHEBI:23872 Beilstein:1820003 Beilstein Gmelin:336103 Gmelin UM-BBD_compID:c0563 UM-BBD dodecyl sulfate IUPAC dodecyl sulfate UniProt Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. chebi_ontology drugs medicine CHEBI:23888 drug CHEBI:23888 drugs ChEBI medicine ChEBI chebi_ontology monoatomic anions CHEBI:23905 monoatomic anion CHEBI:23905 monoatomic anions ChEBI chebi_ontology monoatomic cations CHEBI:23906 monoatomic cation CHEBI:23906 monoatomic cations ChEBI A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. enzyme inhibitor chebi_ontology enzyme inhibitors inhibidor enzimatico inhibidores enzimaticos inhibiteur enzymatique inhibiteurs enzymatiques CHEBI:23924 enzyme inhibitor CHEBI:23924 enzyme inhibitor IUPAC enzyme inhibitors ChEBI inhibidor enzimatico ChEBI inhibidores enzimaticos ChEBI inhibiteur enzymatique ChEBI inhibiteurs enzymatiques ChEBI chebi_ontology CHEBI:23953 erythromycins CHEBI:23953 chebi_ontology CHEBI:23955 erythronolide CHEBI:23955 chebi_ontology ethanolamine CHEBI:23981 ethanolamines CHEBI:23981 ethanolamine ChEBI 0 F InChI=1S/F YCKRFDGAMUMZLT-UHFFFAOYSA-N 18.99840 18.99840 [F] CAS:7782-41-4 WebElements:F fluorine chebi_ontology 9F F Fluor fluor fluorine fluorum CHEBI:24061 fluorine atom CHEBI:24061 CAS:7782-41-4 ChemIDplus fluorine IUPAC 9F IUPAC F IUPAC Fluor ChemIDplus fluor ChEBI fluorine ChEBI fluorum ChEBI fluorine molecular entity chebi_ontology fluorine compounds fluorine molecular entities CHEBI:24062 fluorine molecular entity CHEBI:24062 fluorine molecular entity ChEBI fluorine compounds ChEBI fluorine molecular entities ChEBI An organofluorine compound that consists of an amino acid substituted by a fluoro group. chebi_ontology fluoroamino acids CHEBI:24068 fluoroamino acid CHEBI:24068 fluoroamino acids ChEBI Amides with the general formula R(1)R(2)NCHO (R(1) and R(2) can be H). chebi_ontology CHEBI:24079 formamides CHEBI:24079 A substance used to destroy fungal pests. chebi_ontology fungicides CHEBI:24127 fungicide CHEBI:24127 fungicides ChEBI Compounds containing at least one furan ring. chebi_ontology oxacyclopenta-2,4-dienes CHEBI:24129 furans CHEBI:24129 oxacyclopenta-2,4-dienes ChEBI Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group. chebi_ontology CHEBI:24271 glucosamines CHEBI:24271 chebi_ontology glucosides CHEBI:24278 glucoside CHEBI:24278 glucosides ChEBI An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class. PMID:20716061 chebi_ontology glutamine family amino acids CHEBI:24318 glutamine family amino acid CHEBI:24318 PMID:20716061 Europe PMC glutamine family amino acids ChEBI Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide. CHEBI:24395 CHEBI:5478 glycopeptides chebi_ontology CHEBI:24396 glycopeptide CHEBI:24396 glycopeptides IUPAC A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively. glycosides chebi_ontology O-glycoside O-glycosides glycosides CHEBI:24400 glycoside CHEBI:24400 glycosides IUPAC O-glycoside ChEBI O-glycosides ChEBI glycosides ChEBI A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. chemical entity chebi_ontology CHEBI:24431 chemical entity CHEBI:24431 chemical entity UniProt A role played by the molecular entity or part thereof within a biological context. chebi_ontology biological function CHEBI:24432 biological role CHEBI:24432 biological function ChEBI A defined linked collection of atoms or a single atom within a molecular entity. group chebi_ontology Gruppe Rest groupe grupo grupos CHEBI:24433 group CHEBI:24433 group IUPAC Gruppe ChEBI Rest ChEBI groupe IUPAC grupo IUPAC grupos IUPAC Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas. chebi_ontology CHEBI:24436 guanidines CHEBI:24436 Any non-proteinogenic amino acid carrying at least one halo group. chebi_ontology haloamino acids CHEBI:24470 haloamino acid CHEBI:24470 haloamino acids ChEBI halogen molecular entity chebi_ontology halogen compounds halogen molecular entities CHEBI:24471 halogen molecular entity CHEBI:24471 halogen molecular entity ChEBI halogen compounds ChEBI halogen molecular entities ChEBI halogen halogens chebi_ontology Halogene group 17 elements group VII elements halogene halogenes halogeno halogenos CHEBI:24473 halogen CHEBI:24473 halogen IUPAC halogens IUPAC Halogene ChEBI group 17 elements ChEBI group VII elements ChEBI halogene ChEBI halogenes ChEBI halogeno ChEBI halogenos ChEBI chebi_ontology CHEBI:24531 heterocyclic antibiotic CHEBI:24531 A cyclic compound having as ring members atoms of carbon and at least of one other element. chebi_ontology organic heterocycle organic heterocyclic compounds CHEBI:24532 organic heterocyclic compound CHEBI:24532 organic heterocycle ChEBI organic heterocyclic compounds ChEBI A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond. heterodetic cyclic peptide chebi_ontology heterodetic cyclic peptides peptide cyclique heterodetique peptido ciclico heterodetico CHEBI:24533 heterodetic cyclic peptide CHEBI:24533 heterodetic cyclic peptide IUPAC heterodetic cyclic peptides ChEBI peptide cyclique heterodetique IUPAC peptido ciclico heterodetico IUPAC hexitol chebi_ontology hexitols CHEBI:24583 hexitol CHEBI:24583 hexitol ChEBI hexitols ChEBI Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group. hexosamine chebi_ontology hexosamines CHEBI:24586 hexosamine CHEBI:24586 hexosamine ChEBI hexosamines ChEBI A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages. homodetic cyclic peptide chebi_ontology homodetic cyclic peptides peptide cyclique homodetique peptido ciclico homodetico CHEBI:24613 homodetic cyclic peptide CHEBI:24613 homodetic cyclic peptide IUPAC homodetic cyclic peptides ChEBI peptide cyclique homodetique IUPAC peptido ciclico homodetico IUPAC Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. chebi_ontology endocrine hormones CHEBI:24621 hormone CHEBI:24621 endocrine ChEBI hormones ChEBI An imidazolidinone with oxo groups at position 2 and 4. chebi_ontology CHEBI:24628 imidazolidine-2,4-dione CHEBI:24628 A compound consisting of carbon and hydrogen only. hydrocarbon hydrocarbons chebi_ontology Kohlenwasserstoff Kohlenwasserstoffe hidrocarburo hidrocarburos hydrocarbure CHEBI:24632 hydrocarbon CHEBI:24632 hydrocarbon IUPAC hydrocarbons IUPAC Kohlenwasserstoff ChEBI Kohlenwasserstoffe ChEBI hidrocarburo IUPAC hidrocarburos IUPAC hydrocarbure IUPAC An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid. chebi_ontology hydroxamate hydroxamates hydroxamic acid anions hydroxamic anion hydroxamic anions CHEBI:24648 hydroxamic acid anion CHEBI:24648 hydroxamate ChEBI hydroxamates ChEBI hydroxamic acid anions ChEBI hydroxamic anion ChEBI hydroxamic anions ChEBI A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l =/= 0) by replacing -OH with -NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides. hydroxamic acids chebi_ontology N-hydroxy amide N-hydroxy amides N-hydroxy-amide N-hydroxy-amides N-hydroxyamide N-hydroxyamides hydroxamic acids CHEBI:24650 hydroxamic acid CHEBI:24650 hydroxamic acids IUPAC N-hydroxy amide ChEBI N-hydroxy amides ChEBI N-hydroxy-amide ChEBI N-hydroxy-amides ChEBI N-hydroxyamide ChEBI N-hydroxyamides ChEBI hydroxamic acids ChEBI Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)). chebi_ontology CHEBI:24651 hydroxides CHEBI:24651 Any fatty acid carrying one or more hydroxy substituents. LIPID_MAPS_class:LMFA0105 PMID:18296335 PMID:6419288 PMID:8274032 chebi_ontology hydroxy fatty acids CHEBI:24654 hydroxy fatty acid CHEBI:24654 LIPID_MAPS_class:LMFA0105 LIPID MAPS PMID:18296335 Europe PMC PMID:6419288 Europe PMC PMID:8274032 Europe PMC hydroxy fatty acids LIPID_MAPS Any carboxylic acid with at least one hydroxy group. chebi_ontology hydroxy carboxylic acids hydroxycarboxylic acid hydroxycarboxylic acids CHEBI:24669 hydroxy carboxylic acid CHEBI:24669 hydroxy carboxylic acids ChEBI hydroxycarboxylic acid ChEBI hydroxycarboxylic acids ChEBI Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent. chebi_ontology hydroxybenzoates CHEBI:24675 hydroxybenzoate CHEBI:24675 hydroxybenzoates ChEBI Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring. 0 C7H6O3 138.121 138.03169 CHEBI:50778 hydroxybenzoic acid chebi_ontology hydroxybenzoic acids CHEBI:24676 hydroxybenzoic acid CHEBI:24676 hydroxybenzoic acid IUPAC hydroxybenzoic acids ChEBI An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary alpha-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups. 0 C2H2O2R2 58.036 58.00548 C(C(=O)*)(O)([H])* Wikipedia:Acyloin chebi_ontology acyloin acyloins secondary alpha-hydroxy ketones secondary alpha-hydroxy-ketone secondary alpha-hydroxy-ketones secondary alpha-hydroxyketone secondary alpha-hydroxyketones CHEBI:2468 secondary alpha-hydroxy ketone CHEBI:2468 acyloin ChEBI acyloins ChEBI secondary alpha-hydroxy ketones ChEBI secondary alpha-hydroxy-ketone ChEBI secondary alpha-hydroxy-ketones ChEBI secondary alpha-hydroxyketone ChEBI secondary alpha-hydroxyketones ChEBI 0 CH3O 31.03392 31.01839 C(*)O hydroxymethyl chebi_ontology -CH2-OH serine side-chain CHEBI:24712 hydroxymethyl group CHEBI:24712 hydroxymethyl IUPAC -CH2-OH IUPAC serine side-chain ChEBI chebi_ontology hygromycins CHEBI:24753 hygromycin CHEBI:24753 hygromycins ChEBI A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. chebi_ontology CHEBI:24780 imidazoles CHEBI:24780 imide chebi_ontology imides CHEBI:24782 imide CHEBI:24782 imide ChEBI imides ChEBI chebi_ontology indole phytoalexins CHEBI:24797 indole phytoalexin CHEBI:24797 indole phytoalexins ChEBI Any compound containing an indole skeleton. chebi_ontology CHEBI:24828 indoles CHEBI:24828 A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). oxoacid oxoacids chebi_ontology oxacids oxiacids oxo acid oxy-acids oxyacids CHEBI:24833 oxoacid CHEBI:24833 oxoacid IUPAC oxoacids IUPAC oxacids ChEBI oxiacids ChEBI oxo acid ChEBI oxy-acids ChEBI oxyacids ChEBI chebi_ontology inorganic anions CHEBI:24834 inorganic anion CHEBI:24834 inorganic anions ChEBI A molecular entity that contains no carbon. chebi_ontology anorganische Verbindungen inorganic compounds inorganic entity inorganic molecular entities inorganics CHEBI:24835 inorganic molecular entity CHEBI:24835 anorganische Verbindungen ChEBI inorganic compounds ChEBI inorganic entity ChEBI inorganic molecular entities ChEBI inorganics ChEBI chebi_ontology inorganic oxides CHEBI:24836 inorganic oxide CHEBI:24836 inorganic oxides ChEBI Compounds of structure ROOR' in which R and R' are inorganic groups. inorganic peroxide chebi_ontology inorganic peroxides CHEBI:24837 inorganic peroxide CHEBI:24837 inorganic peroxide ChEBI inorganic peroxides ChEBI chebi_ontology anorganisches Salz inorganic salts CHEBI:24839 inorganic salt CHEBI:24839 anorganisches Salz ChEBI inorganic salts ChEBI chebi_ontology inorganic sulfate salts inorganic sulfates CHEBI:24840 inorganic sulfate salt CHEBI:24840 inorganic sulfate salts ChEBI inorganic sulfates ChEBI Any cyclohexane-1,2,3,4,5,6-hexol. 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H CDAISMWEOUEBRE-UHFFFAOYSA-N 180.15588 180.06339 OC1C(O)C(O)C(O)C(O)C1O inositol inositols chebi_ontology 1,2,3,4,5,6-cyclohexanehexol inositols CHEBI:24848 inositol CHEBI:24848 inositol IUBMB inositols IUPAC 1,2,3,4,5,6-cyclohexanehexol ChEBI inositols ChEBI Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. Wikipedia:Insecticide chebi_ontology insecticides CHEBI:24852 insecticide CHEBI:24852 insecticides ChEBI Chemical element with atomic number 53. 0 I InChI=1S/I ZCYVEMRRCGMTRW-UHFFFAOYSA-N 126.90447 126.90447 [I] WebElements:I iodine chebi_ontology 53I I Iod J Jod iode iodine iodium yodo CHEBI:24859 iodine atom CHEBI:24859 iodine IUPAC 53I IUPAC I ChEBI Iod ChEBI J ChEBI Jod ChEBI iode ChEBI iodine ChEBI iodium ChEBI yodo ChEBI iodine molecular entity chebi_ontology iodine compounds iodine molecular entities CHEBI:24860 iodine molecular entity CHEBI:24860 iodine molecular entity ChEBI iodine compounds ChEBI iodine molecular entities ChEBI A salt is an assembly of cations and anions. salt chebi_ontology Salz Salze ionic compound ionic compounds sal sales salts sel sels CHEBI:24866 salt CHEBI:24866 salt IUPAC Salz ChEBI Salze ChEBI ionic compound ChEBI ionic compounds ChEBI sal ChEBI sales ChEBI salts ChEBI sel ChEBI sels ChEBI chebi_ontology monoatomic ions CHEBI:24867 monoatomic ion CHEBI:24867 monoatomic ions ChEBI chebi_ontology organic salts organisches Salz CHEBI:24868 organic salt CHEBI:24868 organic salts ChEBI organisches Salz ChEBI A compound which can carry specific ions through membranes of cells or organelles. Wikipedia:Ionophore ionophore chebi_ontology ionophores CHEBI:24869 ionophore CHEBI:24869 ionophore IUPAC ionophores ChEBI A molecular entity having a net electric charge. Ion ion chebi_ontology Ionen iones ions CHEBI:24870 ion CHEBI:24870 Ion ChEBI ion ChEBI ion IUPAC Ionen ChEBI iones ChEBI ions ChEBI chebi_ontology CHEBI:24897 isoindoles CHEBI:24897 Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives. LIPID_MAPS_class:LMPR01 PMID:12769708 PMID:19219049 isoprenoid isoprenoids chebi_ontology isoprenoids CHEBI:24913 isoprenoid CHEBI:24913 LIPID_MAPS_class:LMPR01 LIPID MAPS PMID:12769708 Europe PMC PMID:19219049 Europe PMC isoprenoid ChEBI isoprenoids IUPAC isoprenoids ChEBI chebi_ontology CHEBI:24951 kanamycins CHEBI:24951 Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. lactam lactams chebi_ontology Laktam Laktame lactams CHEBI:24995 lactam CHEBI:24995 lactam IUPAC lactams IUPAC Laktam ChEBI Laktame ChEBI lactams ChEBI Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. lactone lactones chebi_ontology Lacton Lakton Laktone lactona lactonas CHEBI:25000 lactone CHEBI:25000 lactone IUPAC lactones IUPAC Lacton ChEBI Lakton ChEBI Laktone ChEBI lactona IUPAC lactonas IUPAC chebi_ontology CHEBI:25022 leucomycin CHEBI:25022 chebi_ontology CHEBI:25061 lipopeptide antibiotic CHEBI:25061 A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity. chebi_ontology Makrolidantibiotika macrolide antibiotics CHEBI:25105 macrolide antibiotic CHEBI:25105 Makrolidantibiotika ChEBI macrolide antibiotics ChEBI A macrocyclic lactone with a ring of twelve or more members derived from a polyketide. Wikipedia:Macrolide macrolide macrolides chebi_ontology Makrolid macrolides CHEBI:25106 macrolide CHEBI:25106 macrolide ChEBI macrolides IUPAC Makrolid ChEBI macrolides ChEBI manganese molecular entity chebi_ontology manganese compounds manganese molecular entities CHEBI:25154 manganese molecular entity CHEBI:25154 manganese molecular entity ChEBI manganese compounds ChEBI manganese molecular entities ChEBI A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group. 0 C4H10O2S2 InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2 VHJLVAABSRFDPM-UHFFFAOYSA-N 154.25300 154.01222 OC(CS)C(O)CS Beilstein:8141671 CAS:7634-42-6 1,4-dimercaptobutane-2,3-diol 1,4-disulfanylbutane-2,3-diol chebi_ontology 1,4-dimercapto-2,3-butanediol CHEBI:25189 1,4-dimercaptobutane-2,3-diol CHEBI:25189 Beilstein:8141671 Beilstein CAS:7634-42-6 ChemIDplus 1,4-dimercaptobutane-2,3-diol ChemIDplus 1,4-disulfanylbutane-2,3-diol IUPAC 1,4-dimercapto-2,3-butanediol ChemIDplus Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. CHEBI:26619 CHEBI:35220 metabolite chebi_ontology metabolites primary metabolites secondary metabolites CHEBI:25212 metabolite CHEBI:25212 metabolite IUPAC metabolites ChEBI primary metabolites ChEBI secondary metabolites ChEBI chebi_ontology a metal cation metal cations CHEBI:25213 metal cation CHEBI:25213 a metal cation UniProt metal cations ChEBI Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. 0 C2H3O2R 59.044 59.01330 COC([*])=O chebi_ontology carboxylic acid methyl ester carboxylic acid methyl esters CHEBI:25248 methyl ester CHEBI:25248 carboxylic acid methyl ester ChEBI carboxylic acid methyl esters ChEBI chebi_ontology mitochondrial electron transport chain inhibitors mitochondrial electron-transport chain inhibitor mitochondrial respiratory chain inhibitors CHEBI:25355 mitochondrial respiratory-chain inhibitor CHEBI:25355 mitochondrial electron transport chain inhibitors ChEBI mitochondrial electron-transport chain inhibitor ChEBI mitochondrial respiratory chain inhibitors ChEBI Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. molecule chebi_ontology Molekuel molecula molecules neutral molecular compounds CHEBI:25367 molecule CHEBI:25367 molecule IUPAC Molekuel ChEBI molecula IUPAC molecules IUPAC neutral molecular compounds IUPAC An oxoacid containing a single carboxy group. chebi_ontology monocarboxylic acids CHEBI:25384 monocarboxylic acid CHEBI:25384 monocarboxylic acids ChEBI A hydroxybenzoate carrying a single hydroxy substituent at unspecified position. chebi_ontology monohydroxybenzoates CHEBI:25388 monohydroxybenzoate CHEBI:25388 monohydroxybenzoates ChEBI Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring. chebi_ontology monohydroxybenzoic acids CHEBI:25389 monohydroxybenzoic acid CHEBI:25389 monohydroxybenzoic acids ChEBI +1 0.00000 [*+] chebi_ontology monoatomic monocations monovalent inorganic cations CHEBI:25414 monoatomic monocation CHEBI:25414 monoatomic monocations ChEBI monovalent inorganic cations ChEBI An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. Wikipedia:Mutagen chebi_ontology mutagene mutagenes mutagenic agent mutageno mutagenos mutagens CHEBI:25435 mutagen CHEBI:25435 mutagene ChEBI mutagenes ChEBI mutagenic agent ChEBI mutageno ChEBI mutagenos ChEBI mutagens ChEBI Poisonous substance produced by fungi. chebi_ontology fungal toxins mycotoxins CHEBI:25442 mycotoxin CHEBI:25442 fungal toxins ChEBI mycotoxins ChEBI chebi_ontology CHEBI:25471 naphthalenemonosulfonate CHEBI:25471 Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings. chebi_ontology CHEBI:25477 naphthalenes CHEBI:25477 chebi_ontology CHEBI:25478 naphthalenesulfonate CHEBI:25478 A polycyclic aromatic ketone metabolite of naphthalene. chebi_ontology naphthoquinones CHEBI:25481 naphthoquinone CHEBI:25481 naphthoquinones ChEBI A substance used to destroy pests of the phylum Nematoda (roundworms). Wikipedia:Nematicide chebi_ontology nematicides nematocide nematocides CHEBI:25491 nematicide CHEBI:25491 nematicides ChEBI nematocide ChEBI nematocides ChEBI An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. Wikipedia:Neurotransmitter chebi_ontology neurotransmitters CHEBI:25512 neurotransmitter CHEBI:25512 neurotransmitters ChEBI A member of the class of pyridines that is a substituted pyridine in which at least one of the substituents is a carboxamide or N-substituted caraboxamide group. chebi_ontology pyridinecarboxamides CHEBI:25529 pyridinecarboxamide CHEBI:25529 pyridinecarboxamides ChEBI 0 N 14.007 14.00307 WebElements:N nitrogen chebi_ontology 7N N Stickstoff azote nitrogen nitrogeno CHEBI:25555 nitrogen atom CHEBI:25555 nitrogen IUPAC 7N IUPAC N IUPAC Stickstoff ChEBI azote IUPAC nitrogen ChEBI nitrogeno ChEBI chebi_ontology organonitrogen heterocyclic antibiotics CHEBI:25558 organonitrogen heterocyclic antibiotic CHEBI:25558 organonitrogen heterocyclic antibiotics ChEBI nonmetal chebi_ontology Nichtmetall Nichtmetalle no metal no metales non-metal non-metaux nonmetal nonmetals CHEBI:25585 nonmetal atom CHEBI:25585 nonmetal IUPAC Nichtmetall ChEBI Nichtmetalle ChEBI no metal ChEBI no metales ChEBI non-metal ChEBI non-metaux ChEBI nonmetal ChEBI nonmetals ChEBI chebi_ontology CHEBI:25605 nucleoside antibiotic CHEBI:25605 A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates. KEGG:C01329 chebi_ontology NMP nucleoside phosphates CHEBI:25608 nucleoside phosphate CHEBI:25608 NMP KEGG_COMPOUND nucleoside phosphates ChEBI Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. 0 C43H64O10R5 740.964 740.44995 [C@@H]1([C@H](CC([C@]2(O1)C([C@@H]3OC(C=C[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C([C@@]([C@@H](O)[C@H](C)CC=CC=C[C@@H](CC[C@@H]([C@H]3C)O2)CC)(*)C)=O)=O)(*)*)=*)C)C[C@H](O)* Wikipedia:Oligomycin chebi_ontology oligomycins CHEBI:25675 oligomycin CHEBI:25675 oligomycins ChEBI A peptide containing a relatively small number of amino acids. CHEBI:7755 Wikipedia:Oligopeptide oligopeptides chebi_ontology Oligopeptid oligopeptido CHEBI:25676 oligopeptide CHEBI:25676 oligopeptides IUPAC Oligopeptid ChEBI oligopeptido ChEBI chebi_ontology organic heteromonocyclic compounds CHEBI:25693 organic heteromonocyclic compound CHEBI:25693 organic heteromonocyclic compounds ChEBI Any organic ion with a net negative charge. chebi_ontology organic anions CHEBI:25696 organic anion CHEBI:25696 organic anions ChEBI Any organic ion with a net positive charge. chebi_ontology organic cations CHEBI:25697 organic cation CHEBI:25697 organic cations ChEBI An organooxygen compound with formula ROR, where R is not hydrogen. 0 OR2 15.99940 15.99491 [*]O[*] ether ethers chebi_ontology ethers CHEBI:25698 ether CHEBI:25698 ether IUPAC ethers IUPAC ethers ChEBI chebi_ontology organic ions CHEBI:25699 organic ion CHEBI:25699 organic ions ChEBI Wikipedia:Organophosphate organic phosphate chebi_ontology organic phosphate ester organic phosphate esters organic phosphates organophosphate ester organophosphate esters CHEBI:25703 organic phosphate CHEBI:25703 organic phosphate ChEBI organic phosphate ester ChEBI organic phosphate esters ChEBI organic phosphates ChEBI organophosphate ester ChEBI organophosphate esters ChEBI Compounds of the general formula SO3HOR where R is an organyl group chebi_ontology organic sulfates CHEBI:25704 organic sulfate CHEBI:25704 organic sulfates ChEBI An alcohol derived from an aliphatic compound. 0 HOR 17.007 17.00274 O* KEGG:C02525 Aliphatic alcohol chebi_ontology aliphatic alcohols an aliphatic alcohol CHEBI:2571 aliphatic alcohol CHEBI:2571 Aliphatic alcohol KEGG_COMPOUND aliphatic alcohols ChEBI an aliphatic alcohol UniProt An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters. Wikipedia:Organophosphorus_compound organophosphorus compound chebi_ontology organophosphorus compounds CHEBI:25710 organophosphorus compound CHEBI:25710 organophosphorus compound ChEBI organophosphorus compounds ChEBI A solute used by a cell under water stress to maintain cell volume. chebi_ontology osmolytes CHEBI:25728 osmolyte CHEBI:25728 osmolytes ChEBI An oxide is a chemical compound of oxygen with other chemical elements. oxide chebi_ontology oxides CHEBI:25741 oxide CHEBI:25741 oxide ChEBI oxides ChEBI Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes. 0 CHNOR2 43.02470 43.00581 O\N=C(\[*])[*] oxime oximes chebi_ontology oximes CHEBI:25750 oxime CHEBI:25750 oxime IUPAC oximes IUPAC oximes ChEBI Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule. oxo carboxylic acids chebi_ontology oxo acids oxo carboxylic acids CHEBI:25754 oxo carboxylic acid CHEBI:25754 oxo carboxylic acids IUPAC oxo acids IUPAC oxo carboxylic acids ChEBI Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety. chebi_ontology CHEBI:2580 unsaturated fatty acid anion CHEBI:2580 0 O InChI=1S/O QVGXLLKOCUKJST-UHFFFAOYSA-N 15.99940 15.99491 [O] KEGG:C00007 WebElements:O oxygen chebi_ontology 8O O Sauerstoff oxigeno oxygen oxygene CHEBI:25805 oxygen atom CHEBI:25805 oxygen IUPAC 8O IUPAC O IUPAC Sauerstoff ChEBI oxigeno ChEBI oxygen ChEBI oxygene ChEBI oxygen molecular entity chebi_ontology oxygen molecular entities CHEBI:25806 oxygen molecular entity CHEBI:25806 oxygen molecular entity ChEBI oxygen molecular entities ChEBI chebi_ontology CHEBI:25807 organooxygen heterocyclic antibiotic CHEBI:25807 A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring. chebi_ontology p-quinone para-quinones CHEBI:25830 p-quinones CHEBI:25830 p-quinone ChEBI para-quinones ChEBI chebi_ontology CHEBI:25865 penicillanic acids CHEBI:25865 aldopentose phosphate chebi_ontology aldopentose phosphates CHEBI:25900 aldopentose phosphate CHEBI:25900 aldopentose phosphate ChEBI aldopentose phosphates ChEBI A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose). pentose chebi_ontology pentoses CHEBI:25901 pentose CHEBI:25901 pentose ChEBI pentoses ChEBI A chemically diverse class of peptides that exhibit antimicrobial properties. MetaCyc:Peptide-Antibiotics PMID:33398258 chebi_ontology peptide antibiotics CHEBI:25903 peptide antibiotic CHEBI:25903 PMID:33398258 Europe PMC peptide antibiotics ChEBI Compounds of structure ROOR'. 0 O2R2 31.999 31.98983 [*]OO[*] chebi_ontology a peroxide CHEBI:25940 peroxides CHEBI:25940 a peroxide UniProt Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Wikipedia:Pesticide pesticide chebi_ontology Pestizid Pestizide pesticides CHEBI:25944 pesticide CHEBI:25944 pesticide IUPAC Pestizid ChEBI Pestizide ChEBI pesticides ChEBI Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin. Wikipedia:Phenylpropanoid chebi_ontology phenylpropanoids CHEBI:26004 phenylpropanoid CHEBI:26004 phenylpropanoids ChEBI Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. phosphates chebi_ontology phosphates CHEBI:26020 phosphate CHEBI:26020 phosphates IUPAC phosphates ChEBI chebi_ontology CHEBI:26045 phosphite ion CHEBI:26045 HP(=O)(OH)2 (phosphonic acid) and its P-substituted derivatives. phosphonic acids chebi_ontology CHEBI:26069 phosphonic acids CHEBI:26069 phosphonic acids IUPAC A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. 0 H3O4P InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4) NBIIXXVUZAFLBC-UHFFFAOYSA-N 97.99520 97.97690 [H]OP(=O)(O[H])O[H] Beilstein:1921286 CAS:7664-38-2 Drug_Central:4478 Gmelin:2000 HMDB:HMDB0002142 KEGG:C00009 KEGG:D05467 KNApSAcK:C00007408 PMID:11455380 PMID:15630224 PMID:17439666 PMID:17518491 PMID:22282755 PMID:22333268 PMID:22381614 PMID:22401268 Reaxys:1921286 Wikipedia:Phosphoric_Acid Phosphoric acid phosphoric acid tetraoxophosphoric acid trihydrogen tetraoxophosphate(3-) trihydroxidooxidophosphorus chebi_ontology H3PO4 Orthophosphoric acid Phosphate Phosphorsaeure Phosphorsaeureloesungen [PO(OH)3] acide phosphorique acidum phosphoricum orthophosphoric acid CHEBI:26078 phosphoric acid CHEBI:26078 Beilstein:1921286 Beilstein CAS:7664-38-2 ChemIDplus CAS:7664-38-2 KEGG COMPOUND CAS:7664-38-2 NIST Chemistry WebBook Drug_Central:4478 DrugCentral Gmelin:2000 Gmelin PMID:11455380 Europe PMC PMID:15630224 Europe PMC PMID:17439666 Europe PMC PMID:17518491 Europe PMC PMID:22282755 Europe PMC PMID:22333268 Europe PMC PMID:22381614 Europe PMC PMID:22401268 Europe PMC Reaxys:1921286 Reaxys Phosphoric acid KEGG_COMPOUND phosphoric acid IUPAC tetraoxophosphoric acid IUPAC trihydrogen tetraoxophosphate(3-) IUPAC trihydroxidooxidophosphorus IUPAC H3PO4 IUPAC Orthophosphoric acid KEGG_COMPOUND Phosphate KEGG_COMPOUND Phosphorsaeure ChEBI Phosphorsaeureloesungen ChEBI [PO(OH)3] IUPAC acide phosphorique ChEBI acidum phosphoricum ChEBI orthophosphoric acid NIST_Chemistry_WebBook chebi_ontology CHEBI:26079 phosphoric acid derivative CHEBI:26079 chebi_ontology phosphorus molecular entities CHEBI:26082 phosphorus molecular entity CHEBI:26082 phosphorus molecular entities ChEBI A member of the class of benzoic acids in that consists of benzene substituted by two carboxy groups (A closed class). 0 C8H6O4 166.131 166.02661 benzenedicarboxylic acid chebi_ontology CHEBI:26094 benzenedicarboxylic acid CHEBI:26094 benzenedicarboxylic acid IUPAC A toxin made by a plant that acts against an organism attacking it. chebi_ontology phytoalexins CHEBI:26115 phytoalexin CHEBI:26115 phytoalexins ChEBI An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. chebi_ontology pigments CHEBI:26130 biological pigment CHEBI:26130 pigments ChEBI chebi_ontology CHEBI:26144 piperazines CHEBI:26144 chebi_ontology CHEBI:26151 piperidines CHEBI:26151 A chemical, natural or artificial, that can affect the rate of growth of a plant. chebi_ontology plant growth regulators CHEBI:26155 plant growth regulator CHEBI:26155 plant growth regulators ChEBI Any amino acid whose side chain is capable of forming one or more hydrogen bonds. 0 C2H4NO2R 74.059 74.02420 OC(C(*)N)=O CHEBI:8283 MetaCyc:Polar-amino-acids PMID:12016058 polar amino acid chebi_ontology polar amino acids polar amino-acid polar amino-acids CHEBI:26167 polar amino acid CHEBI:26167 PMID:12016058 Europe PMC polar amino acid ChEBI polar amino acids ChEBI polar amino-acid ChEBI polar amino-acids ChEBI A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of Streptomyces. chebi_ontology polyene antibiotics CHEBI:26177 polyene antibiotic CHEBI:26177 polyene antibiotics ChEBI Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides. polyketide chebi_ontology polyketides CHEBI:26188 polyketide CHEBI:26188 polyketide ChEBI polyketides ChEBI A compound that contains two or more hydroxy groups. chebi_ontology polyols CHEBI:26191 polyol CHEBI:26191 polyols ChEBI Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group. Wikipedia:Polyphenol chebi_ontology polyphenols CHEBI:26195 polyphenol CHEBI:26195 polyphenols ChEBI Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units. 0 (C5H8)nC10H18O CHEBI:8317 KEGG:C06081 chebi_ontology polyprenols CHEBI:26199 polyprenol CHEBI:26199 polyprenols ChEBI Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome. PMID:14977874 PMID:16380690 PMID:17891522 chebi_ontology PUFA PUFAs polyunsaturated fatty acids CHEBI:26208 polyunsaturated fatty acid CHEBI:26208 PMID:14977874 Europe PMC PMID:16380690 Europe PMC PMID:17891522 Europe PMC PUFA ChEBI PUFAs ChEBI polyunsaturated fatty acids ChEBI 0 K InChI=1S/K ZLMJMSJWJFRBEC-UHFFFAOYSA-N 39.09830 38.96371 [K] CAS:7440-09-7 DrugBank:DB01345 KEGG:C00238 WebElements:K potassium chebi_ontology 19K K Kalium kalium potasio potassium CHEBI:26216 potassium atom CHEBI:26216 CAS:7440-09-7 ChemIDplus potassium IUPAC 19K IUPAC K IUPAC Kalium ChemIDplus kalium IUPAC potasio ChEBI potassium ChEBI potassium molecular entity chebi_ontology potassium molecular entities CHEBI:26217 potassium molecular entity CHEBI:26217 potassium molecular entity ChEBI potassium molecular entities ChEBI Any alkali metal salt having potassium(1+) as the cation. chebi_ontology Kaliumsalz Kaliumsalze potassium salts CHEBI:26218 potassium salt CHEBI:26218 Kaliumsalz ChEBI Kaliumsalze ChEBI potassium salts ChEBI Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids). PMID:3113948 PMID:4207873 prenols chebi_ontology CHEBI:26244 prenols CHEBI:26244 PMID:3113948 Europe PMC PMID:4207873 Europe PMC prenols IUPAC An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2. 0 C5H9NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8) ONIBWKKTOPOVIA-UHFFFAOYSA-N 115.13050 115.06333 OC(=O)C1CCCN1 Beilstein:80809 CAS:609-36-9 Gmelin:26927 KEGG:C16435 PMID:16534801 PMID:21400017 PMID:21903295 PMID:22264337 PMID:22280966 PMID:22770225 Reaxys:80809 Wikipedia:Proline proline chebi_ontology DL-Proline Hpro Prolin prolina pyrrolidine-2-carboxylic acid CHEBI:26271 proline CHEBI:26271 Beilstein:80809 Beilstein CAS:609-36-9 ChemIDplus CAS:609-36-9 KEGG COMPOUND CAS:609-36-9 NIST Chemistry WebBook Gmelin:26927 Gmelin PMID:16534801 Europe PMC PMID:21400017 Europe PMC PMID:21903295 Europe PMC PMID:22264337 Europe PMC PMID:22280966 Europe PMC PMID:22770225 Europe PMC Reaxys:80809 Reaxys proline ChEBI proline IUPAC DL-Proline KEGG_COMPOUND Hpro IUPAC Prolin ChEBI prolina ChEBI pyrrolidine-2-carboxylic acid IUPAC An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues. chebi_ontology proline derivatives CHEBI:26273 proline derivative CHEBI:26273 proline derivatives ChEBI Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine. amidine amidines chebi_ontology Amidines amidines CHEBI:2634 amidine CHEBI:2634 amidine IUPAC amidines IUPAC Amidines KEGG_COMPOUND amidines ChEBI An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group. 0 C22H43N5O13 InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1 LKCWBDHBTVXHDL-RMDFUYIESA-N 585.60272 585.28574 NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O Beilstein:5915117 CAS:37517-28-5 DrugBank:DB00479 Drug_Central:157 HMDB:HMDB0014622 KEGG:C06820 KEGG:D02543 LINCS:LSM-5935 MetaCyc:CPD-14197 PMID:11744283 PMID:15305513 PMID:17365906 PMID:19495517 PMID:19752274 PMID:20195673 PMID:25296102 PMID:25327505 PMID:25339395 PMID:25630642 PMID:8622103 PMID:8622117 PMID:9327246 Patent:DE2234315 Patent:US3781268 Reaxys:5915117 Wikipedia:Amikacin (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide Amikacin chebi_ontology 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine amikacin amikacina amikacine amikacinum CHEBI:2637 amikacin CHEBI:2637 Beilstein:5915117 Beilstein CAS:37517-28-5 ChemIDplus CAS:37517-28-5 KEGG COMPOUND Drug_Central:157 DrugCentral PMID:11744283 Europe PMC PMID:15305513 Europe PMC PMID:17365906 Europe PMC PMID:19495517 Europe PMC PMID:19752274 Europe PMC PMID:20195673 Europe PMC PMID:25296102 Europe PMC PMID:25327505 Europe PMC PMID:25339395 Europe PMC PMID:25630642 Europe PMC PMID:8622103 Europe PMC PMID:8622117 Europe PMC PMID:9327246 Europe PMC Reaxys:5915117 Reaxys (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide IUPAC Amikacin KEGG_COMPOUND 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A ChemIDplus O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine ChemIDplus amikacin ChemIDplus amikacina ChemIDplus amikacine ChemIDplus amikacinum ChemIDplus Any nucleotide that has a purine nucleobase. chebi_ontology purine nucleotides CHEBI:26395 purine nucleotide CHEBI:26395 purine nucleotides ChEBI Any ribonucleotide that has a purine nucleobase. chebi_ontology purine ribonucleotides CHEBI:26400 purine ribonucleotide CHEBI:26400 purine ribonucleotides ChEBI A class of imidazopyrimidines that consists of purine and its substituted derivatives. 0 C5N4R7 116.080 116.01230 CHEBI:13678 chebi_ontology CHEBI:26401 purines CHEBI:26401 chebi_ontology pyridine alkaloids CHEBI:26416 pyridine alkaloid CHEBI:26416 pyridine alkaloids ChEBI A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring. chebi_ontology pyridinemonocarboxylic acids CHEBI:26420 pyridinemonocarboxylic acid CHEBI:26420 pyridinemonocarboxylic acids ChEBI Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives. chebi_ontology CHEBI:26421 pyridines CHEBI:26421 A nucleobase whose skeleton is derived from pyrimidine. 0 C4HN2R4 77.064 77.01397 N1C(=C(C(=NC1=*)*)*)* pyrimidine nucleobase chebi_ontology a pyrimidine nucleobase pyrimidine bases pyrimidine nucleobases CHEBI:26432 pyrimidine nucleobase CHEBI:26432 pyrimidine nucleobase ChEBI a pyrimidine nucleobase UniProt pyrimidine bases ChEBI pyrimidine nucleobases ChEBI KEGG:C03169 chebi_ontology N-D-Ribosylpyrimidine pyrimidine nucleosides CHEBI:26440 pyrimidine nucleoside CHEBI:26440 N-D-Ribosylpyrimidine KEGG_COMPOUND pyrimidine nucleosides ChEBI An azole that includes only one N atom and no other heteroatom as a part of the aromatic skeleton. chebi_ontology CHEBI:26455 pyrroles CHEBI:26455 A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen. chebi_ontology CHEBI:26469 quaternary nitrogen compound CHEBI:26469 chebi_ontology quinoline alkaloids CHEBI:26509 quinoline alkaloid CHEBI:26509 quinoline alkaloids ChEBI Any aromatic carboxylic acid that contains a quinoline moiety that is substituted by one carboxy substituent. chebi_ontology quinolinemonocarboxylic acids CHEBI:26512 quinolinemonocarboxylic acid CHEBI:26512 quinolinemonocarboxylic acids ChEBI A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring. chebi_ontology CHEBI:26513 quinolines CHEBI:26513 Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. Wikipedia:Reactive_oxygen_species chebi_ontology ROS CHEBI:26523 reactive oxygen species CHEBI:26523 ROS ChEBI chebi_ontology ribonucleotides CHEBI:26561 ribonucleotide CHEBI:26561 ribonucleotides ChEBI ribose phosphate chebi_ontology ribose phosphates CHEBI:26562 ribose phosphate CHEBI:26562 ribose phosphate ChEBI ribose phosphates ChEBI Wikipedia:Rifamycin chebi_ontology rifamycin CHEBI:26580 rifamycins CHEBI:26580 rifamycin ChEBI Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure. chebi_ontology s-triazines CHEBI:26588 1,3,5-triazines CHEBI:26588 s-triazines ChEBI Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess. PMID:16492686 PMID:19763019 PMID:20237329 saturated fatty acid chebi_ontology SFA SFAs saturated fatty acids CHEBI:26607 saturated fatty acid CHEBI:26607 PMID:16492686 Europe PMC PMID:19763019 Europe PMC PMID:20237329 Europe PMC saturated fatty acid ChEBI SFA ChEBI SFAs ChEBI saturated fatty acids ChEBI An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues. chebi_ontology serine derivatives CHEBI:26649 serine derivative CHEBI:26649 serine derivatives ChEBI Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). LIPID_MAPS_class:LMPR0103 chebi_ontology sesquiterpenoides sesquiterpenoids CHEBI:26658 sesquiterpenoid CHEBI:26658 LIPID_MAPS_class:LMPR0103 LIPID MAPS sesquiterpenoides ChEBI sesquiterpenoids ChEBI An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid. 0 CH2OR 45.017 44.99765 OC([*])=O PMID:16633129 PMID:16870803 PMID:18203540 PMID:20148677 chebi_ontology SCFA SCFAs short-chain fatty acids CHEBI:26666 short-chain fatty acid CHEBI:26666 PMID:16633129 Europe PMC PMID:16870803 Europe PMC PMID:18203540 Europe PMC PMID:20148677 Europe PMC SCFA ChEBI SCFAs ChEBI short-chain fatty acids ChEBI 0 Na InChI=1S/Na KEAYESYHFKHZAL-UHFFFAOYSA-N 22.98977 22.98977 [Na] CAS:7440-23-5 Gmelin:16221 KEGG:C01330 WebElements:Na sodium chebi_ontology 11Na Na Natrium natrium sodio sodium CHEBI:26708 sodium atom CHEBI:26708 CAS:7440-23-5 ChemIDplus Gmelin:16221 Gmelin sodium IUPAC 11Na IUPAC Na IUPAC Natrium ChemIDplus natrium IUPAC sodio ChemIDplus sodium ChEBI An inorganic chloride salt having sodium(1+) as the counterion. 0 ClNa InChI=1S/ClH.Na/h1H;/q;+1/p-1 FAPWRFPIFSIZLT-UHFFFAOYSA-M 58.44247 57.95862 [Na+].[Cl-] Beilstein:3534976 CAS:7647-14-5 Gmelin:13673 KEGG:C13563 KEGG:D02056 MetaCyc:NACL PPDB:595 Reaxys:3534976 Wikipedia:Sodium_Chloride sodium chloride chebi_ontology Kochsalz NaCl Natriumchlorid chlorure de sodium cloruro sodico common salt halite natrii chloridum rock salt salt table salt CHEBI:26710 sodium chloride CHEBI:26710 Beilstein:3534976 Beilstein CAS:7647-14-5 ChemIDplus CAS:7647-14-5 KEGG COMPOUND CAS:7647-14-5 NIST Chemistry WebBook Gmelin:13673 Gmelin Reaxys:3534976 Reaxys sodium chloride ChEBI sodium chloride IUPAC Kochsalz ChEBI NaCl IUPAC Natriumchlorid NIST_Chemistry_WebBook chlorure de sodium ChEBI cloruro sodico ChEBI common salt ChemIDplus halite NIST_Chemistry_WebBook natrii chloridum ChEBI rock salt ChemIDplus salt ChemIDplus table salt ChemIDplus chebi_ontology sodium compounds sodium molecular entities CHEBI:26712 sodium molecular entity CHEBI:26712 sodium compounds ChEBI sodium molecular entities ChEBI Any alkali metal salt having sodium(1+) as the cation. chebi_ontology Natriumsalz Natriumsalze sodium salts CHEBI:26714 sodium salt CHEBI:26714 Natriumsalz ChEBI Natriumsalze ChEBI sodium salts ChEBI Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone. chebi_ontology sphingolipids CHEBI:26739 sphingolipid CHEBI:26739 sphingolipids ChEBI A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. 0 C16H19N3O5S InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 365.40400 365.10454 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccc(O)cc1)C(O)=O CHEBI:133770 Beilstein:4274654 CAS:26787-78-0 DrugBank:DB01060 Drug_Central:192 HMDB:HMDB0015193 KEGG:C06827 KEGG:D07452 LINCS:LSM-5654 PMID:10930630 PMID:11431418 PMID:11906332 PMID:12569987 PMID:12833570 PMID:12850488 PMID:16033609 PMID:2083978 PMID:24595455 PMID:24631718 PMID:24759068 PMID:25998949 PMID:27731424 PMID:28987997 PMID:29017833 Patent:DE1942693 Patent:GB1241844 Patent:GB978178 Patent:US3192198 Reaxys:4274654 VSDB:1741 Wikipedia:Amoxicillin 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid Amoxicillin chebi_ontology (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid AMPC AX Amolin Amopenixin Amoxicillin anhydrous Clamoxyl Moxal alpha-amino-p-hydroxybenzylpenicillin amoxicilina amoxicillin amoxicilline amoxicillinum amoxycilin amoxycillin p-hydroxyampicillin CHEBI:2676 amoxicillin CHEBI:2676 Beilstein:4274654 Beilstein CAS:26787-78-0 ChemIDplus CAS:26787-78-0 KEGG COMPOUND Drug_Central:192 DrugCentral PMID:10930630 Europe PMC PMID:11431418 Europe PMC PMID:11906332 Europe PMC PMID:12569987 Europe PMC PMID:12833570 Europe PMC PMID:12850488 Europe PMC PMID:16033609 Europe PMC PMID:2083978 Europe PMC PMID:24595455 Europe PMC PMID:24631718 Europe PMC PMID:24759068 Europe PMC PMID:25998949 Europe PMC PMID:27731424 Europe PMC PMID:28987997 Europe PMC PMID:29017833 Europe PMC Reaxys:4274654 Reaxys 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC Amoxicillin KEGG_COMPOUND (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid ChemIDplus AMPC DrugBank AX ChEBI Amolin DrugBank Amopenixin DrugBank Amoxicillin anhydrous KEGG_COMPOUND Clamoxyl ChemIDplus Moxal DrugBank alpha-amino-p-hydroxybenzylpenicillin ChemIDplus amoxicilina ChemIDplus amoxicillin KEGG_DRUG amoxicilline ChemIDplus amoxicillinum ChemIDplus amoxycilin ChEBI amoxycillin ChemIDplus p-hydroxyampicillin ChemIDplus chebi_ontology CHEBI:26761 steroid antibiotic CHEBI:26761 0 C14H12 InChI=1S/C14H12/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-12H PJANXHGTPQOBST-UHFFFAOYSA-N 180.24508 180.09390 [H]C(=C([H])c1ccccc1)c1ccccc1 Beilstein:1904445 CAS:588-59-0 Gmelin:67845 Wikipedia:Stilbene 1,1'-(ethene-1,2-diyl)dibenzene stilbene chebi_ontology 1,1'-(1,2-ethenediyl)bis[benzene] 1,1'-(1,2-ethenediyl)bisbenzene 1,1'-(1,2-ethenediyl)dibenzene 1,1'-ethene-1,2-diyldibenzene 1,2-diphenylethylene alpha,beta-diphenylethylene CHEBI:26775 stilbene CHEBI:26775 Beilstein:1904445 ChemIDplus CAS:588-59-0 ChemIDplus CAS:588-59-0 NIST Chemistry WebBook Gmelin:67845 Gmelin 1,1'-(ethene-1,2-diyl)dibenzene IUPAC stilbene ChemIDplus 1,1'-(1,2-ethenediyl)bis[benzene] NIST_Chemistry_WebBook 1,1'-(1,2-ethenediyl)bisbenzene ChemIDplus 1,1'-(1,2-ethenediyl)dibenzene ChemIDplus 1,1'-ethene-1,2-diyldibenzene ChEBI 1,2-diphenylethylene NIST_Chemistry_WebBook alpha,beta-diphenylethylene NIST_Chemistry_WebBook Any olefinic compound characterised by a 1,2-diphenylethylene backbone. chebi_ontology stilbenes stilbenoids CHEBI:26776 stilbenoid CHEBI:26776 stilbenes ChEBI stilbenoids ChEBI chebi_ontology CHEBI:26788 streptomycins CHEBI:26788 chebi_ontology carbohydrate phosphates CHEBI:26816 carbohydrate phosphate CHEBI:26816 carbohydrate phosphates ChEBI An ester of an alcohol and sulfuric acid. 0 O4SR2 96.06300 95.95173 [*]OS(=O)(=O)O[*] chebi_ontology sulfate ester sulfuric acid ester sulfuric acid esters CHEBI:26819 sulfuric ester CHEBI:26819 sulfate ester ChEBI sulfuric acid ester ChEBI sulfuric acid esters ChEBI A macrolide antibiotic used to treat potentially life-threatening fungal infections. 0 C47H73NO17 InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 APKFDSVGJQXUKY-INPOYWNPSA-N 924.07900 923.48785 [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 CHEBI:106303 CHEBI:566395 Beilstein:4645978 CAS:1397-89-3 DrugBank:DB00681 Drug_Central:197 KEGG:C06573 KEGG:D00203 LIPID_MAPS_instance:LMPK06000002 PMID:11429202 PMID:11930683 PMID:15793154 PMID:16120633 PMID:16793999 PMID:1732516 PMID:17507115 PMID:33846129 Patent:US2908611 Reaxys:4645978 Wikipedia:Amphotericin_B (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid chebi_ontology AMPH-B Amphotericine B Liposomal Amphotericin B amfotericina B amphotericin B amphotericine B amphotericinum B CHEBI:2682 amphotericin B CHEBI:2682 Beilstein:4645978 Beilstein CAS:1397-89-3 ChemIDplus CAS:1397-89-3 DrugBank CAS:1397-89-3 KEGG COMPOUND CAS:1397-89-3 KEGG DRUG Drug_Central:197 DrugCentral LIPID_MAPS_instance:LMPK06000002 LIPID MAPS PMID:11429202 Europe PMC PMID:11930683 Europe PMC PMID:15793154 Europe PMC PMID:16120633 Europe PMC PMID:16793999 Europe PMC PMID:1732516 ChEMBL PMID:17507115 ChEMBL PMID:33846129 Europe PMC Reaxys:4645978 Reaxys (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid IUPAC AMPH-B DrugBank Amphotericine B DrugBank Liposomal Amphotericin B DrugBank amfotericina B ChemIDplus amphotericin B KEGG_DRUG amphotericine B ChemIDplus amphotericinum B ChemIDplus Salts and esters of sulfuric acid sulfates chebi_ontology sulfuric acid derivative sulphates CHEBI:26820 sulfates CHEBI:26820 sulfates ChEBI sulfuric acid derivative ChEBI sulphates ChEBI Any sulfur molecular entity that involves either covalently bonded or anionic sulfur. chebi_ontology sulphides CHEBI:26822 sulfide CHEBI:26822 sulphides ChEBI chebi_ontology CHEBI:26830 sulfonium compound CHEBI:26830 0 S InChI=1S/S NINIDFKCEFEMDL-UHFFFAOYSA-N 32.06600 31.97207 [S] CAS:7704-34-9 KEGG:C00087 KEGG:D06527 PPDB:605 WebElements:S sulfur chebi_ontology 16S Elemental sulfur S Schwefel azufre soufre sulfur sulphur theion CHEBI:26833 sulfur atom CHEBI:26833 CAS:7704-34-9 ChemIDplus CAS:7704-34-9 NIST Chemistry WebBook sulfur IUPAC 16S IUPAC Elemental sulfur KEGG_COMPOUND S IUPAC S KEGG_COMPOUND Schwefel ChEBI azufre ChEBI soufre ChEBI sulfur ChEBI sulfur UniProt sulphur ChEBI theion IUPAC sulfur molecular entity chebi_ontology sulfur molecular entities CHEBI:26835 sulfur molecular entity CHEBI:26835 sulfur molecular entity ChEBI sulfur molecular entities ChEBI A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom. 0 H2O4S InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4) QAOWNCQODCNURD-UHFFFAOYSA-N 98.07948 97.96738 [H]OS(=O)(=O)O[H] CAS:7664-93-9 Gmelin:2122 KEGG:C00059 KEGG:D05963 KNApSAcK:C00007530 MolBase:4 PMID:13568755 PMID:16122922 PMID:19397353 PMID:22047659 PMID:22136045 PMID:22204399 PMID:22267186 PMID:22296037 PMID:22364556 PMID:22435616 PPDB:606 Reaxys:2037554 Wikipedia:Sulfuric_acid Sulfuric acid dihydrogen tetraoxosulfate dihydroxidodioxidosulfur hydrogen tetraoxosulfate(2-) hydrogen tetraoxosulfate(VI) sulfuric acid tetraoxosulfuric acid chebi_ontology Acide sulfurique Acido sulfurico Acidum sulfuricum H2SO4 Schwefelsaeureloesungen [S(OH)2O2] [SO2(OH)2] sulphuric acid CHEBI:26836 sulfuric acid CHEBI:26836 CAS:7664-93-9 ChemIDplus CAS:7664-93-9 KEGG COMPOUND CAS:7664-93-9 NIST Chemistry WebBook Gmelin:2122 Gmelin PMID:13568755 Europe PMC PMID:16122922 Europe PMC PMID:19397353 Europe PMC PMID:22047659 Europe PMC PMID:22136045 Europe PMC PMID:22204399 Europe PMC PMID:22267186 Europe PMC PMID:22296037 Europe PMC PMID:22364556 Europe PMC PMID:22435616 Europe PMC Reaxys:2037554 Reaxys Sulfuric acid KEGG_COMPOUND dihydrogen tetraoxosulfate IUPAC dihydroxidodioxidosulfur IUPAC hydrogen tetraoxosulfate(2-) IUPAC hydrogen tetraoxosulfate(VI) IUPAC sulfuric acid ChEBI sulfuric acid IUPAC tetraoxosulfuric acid IUPAC Acide sulfurique ChemIDplus Acido sulfurico ChemIDplus Acidum sulfuricum ChemIDplus H2SO4 IUPAC Schwefelsaeureloesungen ChemIDplus [S(OH)2O2] MolBase [SO2(OH)2] IUPAC sulphuric acid MolBase Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group. Wikipedia:Terpenoid Terpenoid terpenoids chebi_ontology terpenoide terpenoides CHEBI:26873 terpenoid CHEBI:26873 Terpenoid ChEBI terpenoids IUPAC terpenoide IUPAC terpenoides IUPAC A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it. 0 C4H7OR3 71.09780 71.04969 OC(C[*])(C[*])C[*] tertiary alcohol chebi_ontology tertiary alcohols CHEBI:26878 tertiary alcohol CHEBI:26878 tertiary alcohol ChEBI tertiary alcohols ChEBI Any member of the class of chlorobenzenes carrying four chloro groups at unspecified positions. 0 C6H2Cl4 215.892 213.89106 CAS:12408-10-5 tetrachlorobenzene chebi_ontology Tetrachlorbenzol CHEBI:26888 tetrachlorobenzene CHEBI:26888 CAS:12408-10-5 ChemIDplus tetrachlorobenzene IUPAC Tetrachlorbenzol ChEBI A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups. chebi_ontology CHEBI:26895 tetracyclines CHEBI:26895 Any oxacycle having an oxolane (tetrahydrofuran) skeleton. chebi_ontology CHEBI:26912 oxolanes CHEBI:26912 An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. chebi_ontology thiocarboxylic esters CHEBI:26959 thiocarboxylic ester CHEBI:26959 thiocarboxylic esters ChEBI An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms. chebi_ontology heterotricyclic compounds organic heterotricyclic compounds CHEBI:26979 organic heterotricyclic compound CHEBI:26979 heterotricyclic compounds ChEBI organic heterotricyclic compounds ChEBI Poisonous substance produced by a biological organism such as a microbe, animal or plant. Wikipedia:Toxin toxin chebi_ontology toxins CHEBI:27026 toxin CHEBI:27026 toxin IUPAC toxins ChEBI Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Wikipedia:Micronutrient chebi_ontology micronutrients trace elements CHEBI:27027 micronutrient CHEBI:27027 micronutrients ChEBI trace elements ChEBI An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell. transition element chebi_ontology Uebergangselement Uebergangsmetalle metal de transicion metal de transition metales de transicion metaux de transition transition element transition elements transition metal transition metals CHEBI:27081 transition element atom CHEBI:27081 transition element IUPAC Uebergangselement ChEBI Uebergangsmetalle ChEBI metal de transicion ChEBI metal de transition ChEBI metales de transicion ChEBI metaux de transition ChEBI transition element ChEBI transition elements ChEBI transition metal ChEBI transition metals ChEBI Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions. 0 C6H3Cl3 181.447 179.93003 Wikipedia:Trichlorobenzene trichlorobenzene chebi_ontology Trichlorbenzol CHEBI:27096 trichlorobenzene CHEBI:27096 trichlorobenzene IUPAC Trichlorbenzol ChEBI A chemical compound containing three hydroxy groups. chebi_ontology triols CHEBI:27136 triol CHEBI:27136 triols ChEBI chebi_ontology heterobicyclic compounds organic heterobicyclic compounds CHEBI:27171 organic heterobicyclic compound CHEBI:27171 heterobicyclic compounds ChEBI organic heterobicyclic compounds ChEBI A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid. chebi_ontology univalent acyl group univalent carboacyl groups univalent carboxylic acyl groups CHEBI:27207 univalent carboacyl group CHEBI:27207 univalent acyl group ChEBI univalent carboacyl groups ChEBI univalent carboxylic acyl groups ChEBI Any fatty acid containing at least one C=C or C#C bond. LIPID_MAPS_class:LMFA0103 PMID:5322381 chebi_ontology alkene acid olefinic acid unsaturated fatty acids CHEBI:27208 unsaturated fatty acid CHEBI:27208 LIPID_MAPS_class:LMFA0103 LIPID MAPS PMID:5322381 Europe PMC alkene acid ChEBI olefinic acid ChEBI unsaturated fatty acids ChEBI unsaturated fatty acids LIPID_MAPS chebi_ontology CHEBI:27242 uridines CHEBI:27242 A fatty acid which has a chain length greater than C22. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids. 0 CH2OR 45.017 44.99765 OC([*])=O LIPID_MAPS_instance:LMFA01010025 chebi_ontology VLCFA VLCFAs higher fatty acid very long-chain fatty acids CHEBI:27283 very long-chain fatty acid CHEBI:27283 LIPID_MAPS_instance:LMFA01010025 LIPID MAPS VLCFA ChEBI VLCFAs ChEBI higher fatty acid ChEBI very long-chain fatty acids ChEBI Any plant metabolite that is found naturally as a component of a volatile oil. Wikipedia:Essential_oil chebi_ontology essential oil component essential oil components ethereal oil component ethereal oil components volatile oil components CHEBI:27311 volatile oil component CHEBI:27311 essential oil component ChEBI essential oil components ChEBI ethereal oil component ChEBI ethereal oil components ChEBI volatile oil components ChEBI Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. chebi_ontology wasserloesliche Vitamine water-soluble vitamin water-soluble vitamins CHEBI:27314 water-soluble vitamin (role) CHEBI:27314 wasserloesliche Vitamine ChEBI water-soluble vitamin ChEBI water-soluble vitamins ChEBI 0 Zn InChI=1S/Zn HCHKCACWOHOZIP-UHFFFAOYSA-N 65.39000 63.92914 [Zn] CAS:7440-66-6 Gmelin:16321 KEGG:C00038 PDBeChem:ZN WebElements:Zn zinc chebi_ontology 30Zn Zink Zn Zn(II) Zn2+ cinc zinc zincum CHEBI:27363 zinc atom CHEBI:27363 CAS:7440-66-6 ChemIDplus CAS:7440-66-6 KEGG COMPOUND Gmelin:16321 Gmelin zinc IUPAC 30Zn IUPAC Zink ChEBI Zn IUPAC Zn(II) KEGG_COMPOUND Zn2+ KEGG_COMPOUND cinc ChEBI zinc ChEBI zincum ChEBI chebi_ontology zinc compounds zinc molecular entities CHEBI:27364 zinc molecular entity CHEBI:27364 zinc compounds ChEBI zinc molecular entities ChEBI A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer). zwitterion zwitterions chebi_ontology compose zwitterionique compuestos zwitterionicos zwitteriones zwitterionic compounds CHEBI:27369 zwitterion CHEBI:27369 zwitterion IUPAC zwitterions IUPAC compose zwitterionique IUPAC compuestos zwitterionicos IUPAC zwitteriones IUPAC zwitterionic compounds IUPAC An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups. 0 C8H18N6O4 InChI=1S/C8H18N6O4/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14)/t1-,2+,3-,4+,5-,6- MSXMXWJPFIDEMT-FAEUDGQSSA-N 262.26630 262.13895 NC(=N)N[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@@H]1O CHEBI:26781 CHEBI:9280 CAS:85-17-6 HMDB:HMDB0258506 KEGG:C00837 MetaCyc:CPD-10148 PMID:11642734 PMID:15736038 PMID:16956741 PMID:17011831 PMID:17609790 PMID:6076630 Reaxys:2816623 1,1'-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine N,N'''-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine Streptidine chebi_ontology 1,1'-(2,4,5,6-Tetrahydroxy-1,3-cyclohexylene)diguanidine 1,3-diguanidino-2,4,5,6-cyclohexanetetrol N,N'-bis(aminoiminomethyl)streptamine N,N'-diamidinostreptamine Streptamine, N,N'-bis(aminoiminomethyl)- streptidin CHEBI:27405 streptidine CHEBI:27405 CAS:85-17-6 ChemIDplus CAS:85-17-6 KEGG COMPOUND PMID:11642734 Europe PMC PMID:15736038 Europe PMC PMID:16956741 Europe PMC PMID:17011831 Europe PMC PMID:17609790 Europe PMC PMID:6076630 Europe PMC Reaxys:2816623 Reaxys 1,1'-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine IUPAC N,N'''-[(1R,2s,3S,4R,5r,6S)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine IUPAC Streptidine KEGG_COMPOUND 1,1'-(2,4,5,6-Tetrahydroxy-1,3-cyclohexylene)diguanidine ChemIDplus 1,3-diguanidino-2,4,5,6-cyclohexanetetrol ChEBI N,N'-bis(aminoiminomethyl)streptamine ChEBI N,N'-diamidinostreptamine ChEBI Streptamine, N,N'-bis(aminoiminomethyl)- ChemIDplus streptidin ChemIDplus 0 C21H43N5O7 InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9?,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1 CEAZRRDELHUEMR-URQXQFDESA-N 477.59562 477.31625 CNC(C)[C@@H]1CC[C@@H](N)[C@H](O1)O[C@@H]1[C@@H](N)C[C@@H](N)[C@H](O[C@H]2OC[C@](C)(O)[C@H](NC)[C@H]2O)[C@H]1O CHEBI:24209 CHEBI:5309 CAS:25876-10-2 KEGG:C07656 (1R,2S,3S,4R,6S)-4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-beta-L-lyxo-heptopyranoside chebi_ontology Gentamicin C1 O-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-ribo-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-D-streptamine CHEBI:27412 gentamycin C1 CHEBI:27412 CAS:25876-10-2 ChemIDplus CAS:25876-10-2 KEGG COMPOUND (1R,2S,3S,4R,6S)-4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-beta-L-lyxo-heptopyranoside IUPAC Gentamicin C1 KEGG_COMPOUND O-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-ribo-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-D-streptamine ChemIDplus A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. 0 C2H4O InChI=1S/C2H4O/c1-2-3-1/h1-2H2 IAYPIBMASNFSPL-UHFFFAOYSA-N 44.05256 44.02621 C1CO1 CHEBI:24001 CHEBI:4900 Beilstein:102378 CAS:75-21-8 Gmelin:676 HMDB:HMDB0031305 KEGG:C06548 KEGG:D03474 PMID:11437638 PMID:24313866 PMID:24882394 PMID:25005741 PMID:3932500 Reaxys:102378 UM-BBD_compID:c0527 Wikipedia:Oxirane oxirane chebi_ontology 1,2-Epoxyaethan 1,2-epoxyethane Aethylenoxid Amprolene Anprolene Anproline Dihydrooxirene Dimethylene oxide ETO Ethylene oxide Oxacyclopropane Oxane Oxidoethane Oxyfume epoxyethane ethene oxide oxyde d'ethylene CHEBI:27561 oxirane CHEBI:27561 Beilstein:102378 Beilstein CAS:75-21-8 ChemIDplus CAS:75-21-8 KEGG COMPOUND CAS:75-21-8 NIST Chemistry WebBook Gmelin:676 Gmelin PMID:11437638 Europe PMC PMID:24313866 Europe PMC PMID:24882394 Europe PMC PMID:25005741 Europe PMC PMID:3932500 Europe PMC Reaxys:102378 Reaxys UM-BBD_compID:c0527 UM-BBD oxirane IUPAC 1,2-Epoxyaethan ChemIDplus 1,2-epoxyethane NIST_Chemistry_WebBook Aethylenoxid ChemIDplus Amprolene ChemIDplus Anprolene NIST_Chemistry_WebBook Anproline ChemIDplus Dihydrooxirene ChemIDplus Dimethylene oxide ChemIDplus ETO ChemIDplus Ethylene oxide KEGG_COMPOUND Oxacyclopropane ChemIDplus Oxane ChemIDplus Oxidoethane ChemIDplus Oxyfume ChEBI epoxyethane NIST_Chemistry_WebBook ethene oxide NIST_Chemistry_WebBook oxyde d'ethylene ChemIDplus An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. 0 C7H7NO3 InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11) WUBBRNOQWQTFEX-UHFFFAOYSA-N 153.13540 153.04259 Nc1ccc(C(O)=O)c(O)c1 CHEBI:1789 CHEBI:20320 CHEBI:41152 Beilstein:473071 CAS:65-49-6 DrugBank:DB00233 Drug_Central:2050 Gmelin:306153 HMDB:HMDB0014378 KEGG:C02518 KEGG:D00162 LINCS:LSM-5862 PDBeChem:BHA PMID:11621575 PMID:1650428 PMID:23118010 PMID:24663015 PMID:25050392 PMID:25421465 PMID:25605031 PMID:25963985 PMID:26004847 PMID:26033719 PMID:26277036 PMID:26596566 PMID:26848874 PMID:27021327 PMID:27491492 PMID:27617928 PMID:27671064 PMID:28011126 PMID:28223391 PMID:28394286 PMID:28408267 PMID:28567674 PMID:28651968 PMID:28717039 PMID:28812999 Patent:DE50835 Patent:US2844625 Patent:US427564 Reaxys:473071 Wikipedia:Aminosalicylic_Acid 4-Aminosalicylic acid 4-amino-2-hydroxybenzoic acid chebi_ontology 2-HYDROXY-4-AMINOBENZOIC ACID 4-Aminosalicylate Aminosalicylic acid PAS Para-amino salicylic acid Paser p-aminosalicylic acid CHEBI:27565 4-aminosalicylic acid CHEBI:27565 Beilstein:473071 Beilstein CAS:65-49-6 ChemIDplus CAS:65-49-6 KEGG COMPOUND CAS:65-49-6 NIST Chemistry WebBook Drug_Central:2050 DrugCentral Gmelin:306153 Gmelin PMID:11621575 Europe PMC PMID:1650428 Europe PMC PMID:23118010 Europe PMC PMID:24663015 Europe PMC PMID:25050392 Europe PMC PMID:25421465 Europe PMC PMID:25605031 Europe PMC PMID:25963985 Europe PMC PMID:26004847 Europe PMC PMID:26033719 Europe PMC PMID:26277036 Europe PMC PMID:26596566 Europe PMC PMID:26848874 Europe PMC PMID:27021327 Europe PMC PMID:27491492 Europe PMC PMID:27617928 Europe PMC PMID:27671064 Europe PMC PMID:28011126 Europe PMC PMID:28223391 Europe PMC PMID:28394286 Europe PMC PMID:28408267 Europe PMC PMID:28567674 Europe PMC PMID:28651968 Europe PMC PMID:28717039 Europe PMC PMID:28812999 Europe PMC Reaxys:473071 Reaxys 4-Aminosalicylic acid KEGG_COMPOUND 4-amino-2-hydroxybenzoic acid IUPAC 2-HYDROXY-4-AMINOBENZOIC ACID PDBeChem 4-Aminosalicylate KEGG_COMPOUND Aminosalicylic acid ChemIDplus PAS ChemIDplus Para-amino salicylic acid ChemIDplus Paser DrugBank p-aminosalicylic acid NIST_Chemistry_WebBook 0 C InChI=1S/C OKTJSMMVPCPJKN-UHFFFAOYSA-N 12.01070 12.00000 [C] CHEBI:23009 CHEBI:3399 CAS:7440-44-0 KEGG:C06265 WebElements:C carbon chebi_ontology 6C C Carbon Kohlenstoff carbon carbone carbonium carbono CHEBI:27594 carbon atom CHEBI:27594 CAS:7440-44-0 ChemIDplus CAS:7440-44-0 KEGG COMPOUND carbon IUPAC 6C IUPAC C IUPAC C KEGG_COMPOUND Carbon KEGG_COMPOUND Kohlenstoff ChEBI carbon ChEBI carbone ChEBI carbonium ChEBI carbono ChEBI A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. 0 C28H40N2O9 InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1 UIFFUZWRFRDZJC-SBOOETFBSA-N 548.633 548.27338 C1([C@H]([C@H](OC([C@@H]([C@H]([C@@H](O1)C)OC(CC(C)C)=O)CCCCCC)=O)C)NC(C2=C(C(=CC=C2)NC(=O)[H])O)=O)=O CHEBI:22584 CHEBI:40908 Beilstein:72665 CAS:1397-94-0 CAS:642-15-9 KEGG:C11339 MetaCyc:CPD-5744 PDBeChem:AY1 PMID:16819166 PMID:29790043 PMID:30914247 PMID:31079230 PMID:32662599 (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate chebi_ontology Antimycin A1 Antipiricullin Fintrol Virosin antimycin A1b CHEBI:2762 antimycin A CHEBI:2762 Beilstein:72665 Beilstein CAS:1397-94-0 ChemIDplus CAS:642-15-9 ChemIDplus CAS:642-15-9 KEGG COMPOUND PMID:16819166 Europe PMC PMID:29790043 Europe PMC PMID:30914247 Europe PMC PMID:31079230 Europe PMC PMID:32662599 Europe PMC (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate IUPAC Antimycin A1 KEGG_COMPOUND Antipiricullin ChemIDplus Fintrol ChemIDplus Virosin ChemIDplus antimycin A1b ChEBI A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. 0 C15H23NO4 InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1 YPHMISFOHDHNIV-FSZOTQKASA-N 281.352 281.16271 [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1 CHEBI:23484 CHEBI:4015 Beilstein:88868 CAS:66-81-9 KEGG:C06685 KEGG:D03625 KNApSAcK:C00047211 LINCS:LSM-2791 PDBeChem:3HE PMID:11972861 PMID:16659174 PMID:25209664 PMID:26715760 PMID:27192630 PMID:27665925 PMID:30154175 PMID:30916348 PMID:32299921 PMID:33101237 PPDB:1680 Reaxys:88868 Wikipedia:Cycloheximide 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione Cycloheximide cycloheximide chebi_ontology 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide Cycloheximid Zykloheximid cicloheximida cicloheximide cicloheximidum naramycin naramycin A CHEBI:27641 cycloheximide CHEBI:27641 Beilstein:88868 Beilstein CAS:66-81-9 ChemIDplus CAS:66-81-9 KEGG COMPOUND PMID:11972861 Europe PMC PMID:16659174 Europe PMC PMID:25209664 Europe PMC PMID:26715760 Europe PMC PMID:27192630 Europe PMC PMID:27665925 Europe PMC PMID:30154175 Europe PMC PMID:30916348 Europe PMC PMID:32299921 Europe PMC PMID:33101237 Europe PMC Reaxys:88868 Reaxys 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione IUPAC Cycloheximide KEGG_COMPOUND cycloheximide UniProt 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide ChemIDplus Cycloheximid ChEBI Zykloheximid ChEBI cicloheximida ChemIDplus cicloheximide WHO_MedNet cicloheximidum ChemIDplus naramycin ChemIDplus naramycin A ChemIDplus A member of the class of tetracyclines with formula C22H23ClN2O8 isolated from Streptomyces aureofaciens. 0 C22H23ClN2O8 InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31)/t7-,8-,15-,21-,22-/m0/s1 CYDMQBQPVICBEU-XRNKAMNCSA-N 478.88000 478.11429 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)ccc(Cl)c1[C@@]3(C)O CHEBI:23164 CHEBI:3653 CAS:57-62-5 Drug_Central:624 HMDB:HMDB0014401 KEGG:C06571 KEGG:D07689 LIPID_MAPS_instance:LMPK07000004 PDBeChem:CTC PMID:23530364 PMID:24845506 PMID:25131164 PMID:25602656 PMID:7150561 PMID:7390959 PMID:7988792 Patent:US2482055 (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide chebi_ontology 7-Chlorotetracycline Aueromycin chlortetracycline chlortetracyclinum clortetraciclina CHEBI:27644 chlortetracycline CHEBI:27644 CAS:57-62-5 ChemIDplus CAS:57-62-5 KEGG COMPOUND Drug_Central:624 DrugCentral LIPID_MAPS_instance:LMPK07000004 LIPID MAPS PMID:23530364 Europe PMC PMID:24845506 Europe PMC PMID:25131164 Europe PMC PMID:25602656 Europe PMC PMID:7150561 Europe PMC PMID:7390959 Europe PMC PMID:7988792 Europe PMC (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC 7-Chlorotetracycline KEGG_COMPOUND Aueromycin KEGG_DRUG chlortetracycline WHO_MedNet chlortetracyclinum WHO_MedNet clortetraciclina WHO_MedNet A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). 0 C20H16N2O4 InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 348.35200 348.11101 CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O CHEBI:22997 CHEBI:3343 Beilstein:6075662 CAS:7689-03-4 DrugBank:DB04690 KEGG:C01897 KNApSAcK:C00002145 LINCS:LSM-4611 PDBeChem:EHD PMID:11024478 PMID:11549373 PMID:23344961 PMID:23474217 PMID:23676007 PMID:8965250 Reaxys:6075662 Wikipedia:Camptothecin (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Camptothecin chebi_ontology (+)-camptothecin (+)-camptothecine (S)-(+)-camptothecin 20(S)-camptothecine 21,22-Secocamptothecin-21-oic acid lactone CPT Camptothecine D-camptothecin CHEBI:27656 camptothecin CHEBI:27656 Beilstein:6075662 Beilstein CAS:7689-03-4 ChemIDplus PMID:11024478 Europe PMC PMID:11549373 Europe PMC PMID:23344961 Europe PMC PMID:23474217 Europe PMC PMID:23676007 Europe PMC PMID:8965250 Europe PMC Reaxys:6075662 Reaxys (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione IUPAC Camptothecin KEGG_COMPOUND (+)-camptothecin DrugBank (+)-camptothecine DrugBank (S)-(+)-camptothecin DrugBank 20(S)-camptothecine ChemIDplus 21,22-Secocamptothecin-21-oic acid lactone ChemIDplus CPT DrugBank Camptothecine ChemIDplus D-camptothecin DrugBank 0 C62H86N12O16 InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1 RJURFGZVJUQBHK-IIXSONLDSA-N 1255.41700 1254.62847 [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C CHEBI:22218 CHEBI:2446 Beilstein:4173766 CAS:50-76-0 DrugBank:DB00970 Drug_Central:774 KEGG:C06770 KEGG:D00214 LINCS:LSM-5783 Wikipedia:Dactinomycin 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide Actinomycin D chebi_ontology 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide ActD Dactinomycin actinomycin C1 actinomycin IV CHEBI:27666 actinomycin D CHEBI:27666 Beilstein:4173766 Beilstein CAS:50-76-0 ChemIDplus CAS:50-76-0 KEGG COMPOUND Drug_Central:774 DrugCentral 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide IUPAC Actinomycin D KEGG_COMPOUND 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide ChemIDplus ActD ChEBI Dactinomycin KEGG_COMPOUND actinomycin C1 ChEBI actinomycin IV ChemIDplus A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae. 0 C22H24N2O9 InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1 IWVCMVBTMGNXQD-PXOLEDIWSA-N 460.43400 460.14818 [H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C CHEBI:25811 CHEBI:521157 CHEBI:596903 CHEBI:7871 BPDB:503 Beilstein:2686362 Beilstein:2714587 CAS:79-57-2 DrugBank:DB00595 Drug_Central:2041 Gmelin:623487 HMDB:HMDB0014733 KEGG:C06624 KNApSAcK:C00017127 LIPID_MAPS_instance:LMPK07000005 PMID:1650428 PMID:17386724 PMID:17638695 PMID:17870541 PMID:1833366 PMID:21136283 PMID:21488905 PMID:22013404 PMID:24247133 PMID:24281679 PMID:24290103 PMID:24362004 PMID:24510709 PMID:24607684 PMID:24853528 PMID:24983832 PMID:25019386 PMID:25035320 PMID:25081007 Pesticides:oxytetracycline Reaxys:2714587 VSDB:503 Wikipedia:Oxytetracycline (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide chebi_ontology 5-Hydroxytetracycline Oxyterracin Oxyterracine Oxytetracyclin Oxytetracycline (anhydrous) Oxytetracycline amphoteric oxitetraciclina oxytetracyclinum CHEBI:27701 oxytetracycline CHEBI:27701 Beilstein:2686362 Beilstein Beilstein:2714587 Beilstein CAS:79-57-2 ChemIDplus CAS:79-57-2 KEGG COMPOUND Drug_Central:2041 DrugCentral Gmelin:623487 Gmelin LIPID_MAPS_instance:LMPK07000005 LIPID MAPS PMID:1650428 Europe PMC PMID:17386724 Europe PMC PMID:17638695 ChEMBL PMID:17870541 ChEMBL PMID:1833366 Europe PMC PMID:21136283 Europe PMC PMID:21488905 Europe PMC PMID:22013404 Europe PMC PMID:24247133 Europe PMC PMID:24281679 Europe PMC PMID:24290103 Europe PMC PMID:24362004 Europe PMC PMID:24510709 Europe PMC PMID:24607684 Europe PMC PMID:24853528 Europe PMC PMID:24983832 Europe PMC PMID:25019386 Europe PMC PMID:25035320 Europe PMC PMID:25081007 Europe PMC Pesticides:oxytetracycline Alan Wood's Pesticides Reaxys:2714587 Reaxys (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC 5-Hydroxytetracycline ChemIDplus Oxyterracin ChemIDplus Oxyterracine ChemIDplus Oxytetracyclin ChemIDplus Oxytetracycline (anhydrous) ChemIDplus Oxytetracycline amphoteric ChemIDplus oxitetraciclina ChemIDplus oxytetracyclinum ChemIDplus A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. CHEBI:23648 CHEBI:4456 KEGG:C01689 detergent chebi_ontology Detergents CHEBI:27780 detergent CHEBI:27780 detergent IUPAC Detergents KEGG_COMPOUND A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. 0 C7H7N3 InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10) JWYUFVNJZUSCSM-UHFFFAOYSA-N 133.15070 133.06400 Nc1nc2ccccc2[nH]1 CHEBI:1016 CHEBI:19467 Beilstein:116525 CAS:934-32-7 KEGG:C10901 PDBeChem:AX7 PMID:22076761 PMID:22488868 PMID:22958065 PMID:24098350 Reaxys:116525 1H-benzimidazol-2-amine 2-Aminobenzimidazole 2-aminobenzimidazole chebi_ontology 2-Iminobenzimidazoline Benzimidazol-2-ylamine CHEBI:27822 2-aminobenzimidazole CHEBI:27822 Beilstein:116525 Beilstein CAS:934-32-7 ChemIDplus CAS:934-32-7 KEGG COMPOUND CAS:934-32-7 NIST Chemistry WebBook PMID:22076761 Europe PMC PMID:22488868 Europe PMC PMID:22958065 Europe PMC PMID:24098350 Europe PMC Reaxys:116525 Reaxys 1H-benzimidazol-2-amine IUPAC 2-Aminobenzimidazole KEGG_COMPOUND 2-aminobenzimidazole UniProt 2-Iminobenzimidazoline ChemIDplus Benzimidazol-2-ylamine ChemIDplus A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups. 0 C14H12O3 InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H LUKBXSAWLPMMSZ-UHFFFAOYSA-N 228.24328 228.07864 [H]C(=C([H])c1cc(O)cc(O)c1)c1ccc(O)cc1 CHEBI:11685 CHEBI:1366 CHEBI:19867 Beilstein:1912433 CAS:501-36-0 DrugBank:DB02709 KEGG:C03582 LINCS:LSM-2557 PMID:12939617 PMID:16461283 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol Resveratrol chebi_ontology 3,4',5-Trihydroxystilbene CHEBI:27881 resveratrol CHEBI:27881 Beilstein:1912433 Beilstein CAS:501-36-0 KEGG COMPOUND PMID:12939617 Europe PMC PMID:16461283 Europe PMC 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol IUPAC Resveratrol KEGG_COMPOUND 3,4',5-Trihydroxystilbene KEGG_COMPOUND A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. 0 C22H24N2O8 InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1 OFVLGDICTFRJMM-WESIUVDSSA-N 444.43460 444.15327 [H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C CHEBI:26894 CHEBI:45729 CHEBI:9474 Beilstein:2230417 CAS:60-54-8 DrugBank:DB00759 Drug_Central:2611 Gmelin:1103368 KEGG:C06570 KEGG:D00201 MetaCyc:CPD0-1414 PDBeChem:TAC PMID:11061623 PMID:11550419 PMID:11744940 PMID:12934399 PMID:14585720 PMID:15825421 PMID:15913752 PMID:16443056 PMID:1650428 PMID:16749547 PMID:17251127 PMID:17260506 PMID:18326855 PMID:18406588 PMID:19032078 PMID:19112759 PMID:19136803 PMID:25286144 PMID:26876942 Patent:US2699054 Patent:US2712517 Patent:US2886595 Patent:US3005023 Patent:US3019173 Patent:US3301899 Reaxys:2230417 VSDB:1739 Wikipedia:Tetracycline (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide TETRACYCLINE Tetracycline tetracycline chebi_ontology (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Abramycin Achromycin Anhydrotetracycline Deschlorobiomycin Liquamycin Tetracyclin Tetrazyklin Tsiklomitsin tetracycline tetracyclinum CHEBI:27902 tetracycline CHEBI:27902 Beilstein:2230417 Beilstein CAS:60-54-8 ChemIDplus CAS:60-54-8 KEGG COMPOUND Drug_Central:2611 DrugCentral Gmelin:1103368 Gmelin PMID:11061623 Europe PMC PMID:11550419 Europe PMC PMID:11744940 Europe PMC PMID:12934399 Europe PMC PMID:14585720 Europe PMC PMID:15825421 Europe PMC PMID:15913752 Europe PMC PMID:16443056 Europe PMC PMID:1650428 Europe PMC PMID:16749547 Europe PMC PMID:17251127 Europe PMC PMID:17260506 Europe PMC PMID:18326855 Europe PMC PMID:18406588 Europe PMC PMID:19032078 Europe PMC PMID:19112759 Europe PMC PMID:19136803 Europe PMC PMID:25286144 Europe PMC PMID:26876942 Europe PMC Reaxys:2230417 Reaxys (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC TETRACYCLINE PDBeChem Tetracycline KEGG_COMPOUND tetracycline ChEBI (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide ChemIDplus Abramycin ChemIDplus Achromycin ChEBI Anhydrotetracycline DrugBank Deschlorobiomycin ChemIDplus Liquamycin ChemIDplus Tetracyclin ChEBI Tetrazyklin ChEBI Tsiklomitsin ChemIDplus tetracycline ChemIDplus tetracyclinum ChemIDplus An organonitrogen heterocyclic antibiotic that contains a beta-lactam ring. CHEBI:10427 CHEBI:22844 KEGG:C03438 PMID:19254642 PMID:22594007 Wikipedia:Beta-lactam_antibiotic chebi_ontology beta-Lactam antibiotics beta-lactam antibiotics CHEBI:27933 beta-lactam antibiotic CHEBI:27933 PMID:19254642 Europe PMC PMID:22594007 Europe PMC beta-Lactam antibiotics KEGG_COMPOUND beta-lactam antibiotics ChEBI An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups. 0 C6H14N2O4 InChI=1S/C6H14N2O4/c7-1-3(9)2(8)5(11)6(12)4(1)10/h1-6,9-12H,7-8H2/t1-,2+,3-,4+,5-,6- ANLMVXSIPASBFL-FAEUDGQSSA-N 178.18640 178.09536 N[C@H]1[C@H](O)[C@@H](N)[C@H](O)[C@@H](O)[C@@H]1O CHEBI:26779 CHEBI:9277 Beilstein:26714 CAS:488-52-8 KEGG:C01854 Reaxys:2802452 (1R,2r,3S,4R,5s,6S)-4,6-diaminocyclohexane-1,2,3,5-tetrol 1,3-diamino-1,3-dideoxy-scyllo-inositol Streptamine chebi_ontology CHEBI:27955 streptamine CHEBI:27955 Beilstein:26714 Beilstein CAS:488-52-8 ChemIDplus CAS:488-52-8 KEGG COMPOUND Reaxys:2802452 Reaxys (1R,2r,3S,4R,5s,6S)-4,6-diaminocyclohexane-1,2,3,5-tetrol IUPAC 1,3-diamino-1,3-dideoxy-scyllo-inositol IUPAC Streptamine KEGG_COMPOUND A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. 0 C66H75Cl2N9O24 InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-/m0/s1 MYPYJXKWCTUITO-LYRMYLQWSA-N 1449.25336 1447.43020 CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1)c(Cl)c2 CHEBI:27276 CHEBI:49941 CHEBI:9931 Beilstein:3132 CAS:1404-90-6 DrugBank:DB00512 Drug_Central:2807 KEGG:C06689 KEGG:D00212 KNApSAcK:C00016052 MetaCyc:CPD-12245 PDBeChem:VAN PMID:11028184 PMID:11408222 PMID:11688538 PMID:11864951 PMID:11886013 PMID:11980329 PMID:12019070 PMID:12541895 PMID:12852813 PMID:13370625 PMID:13521912 PMID:14605050 PMID:14702667 PMID:15047516 PMID:15081082 PMID:15465645 PMID:15590714 PMID:15792257 PMID:16183423 PMID:16184232 PMID:16420976 PMID:16596002 PMID:16720708 PMID:17027219 PMID:17184835 PMID:17299012 PMID:17594206 PMID:18030187 PMID:18159039 PMID:18162343 PMID:18260149 PMID:18361944 PMID:18462092 PMID:18582342 PMID:18817166 PMID:18983037 PMID:19107100 PMID:19830166 PMID:20956604 PMID:21109901 PMID:21458937 PMID:21466775 PMID:21664803 PMID:21719238 PMID:21951032 PMID:22011388 PMID:22015328 PMID:22027450 PMID:22124537 Patent:US3067099 Reaxys:3132 Wikipedia:Vancomycin (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid VANCOMYCIN Vancomycin chebi_ontology (1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):C(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine] Vancocin vancomicin vancomicina vancomycin vancomycine vancomycinum CHEBI:28001 vancomycin CHEBI:28001 Beilstein:3132 Beilstein CAS:1404-90-6 ChemIDplus CAS:1404-90-6 KEGG COMPOUND Drug_Central:2807 DrugCentral PMID:11028184 Europe PMC PMID:11408222 Europe PMC PMID:11688538 Europe PMC PMID:11864951 Europe PMC PMID:11886013 Europe PMC PMID:11980329 Europe PMC PMID:12019070 Europe PMC PMID:12541895 Europe PMC PMID:12852813 Europe PMC PMID:13370625 Europe PMC PMID:13521912 Europe PMC PMID:14605050 Europe PMC PMID:14702667 Europe PMC PMID:15047516 Europe PMC PMID:15081082 Europe PMC PMID:15465645 Europe PMC PMID:15590714 Europe PMC PMID:15792257 Europe PMC PMID:16183423 Europe PMC PMID:16184232 Europe PMC PMID:16420976 Europe PMC PMID:16596002 Europe PMC PMID:16720708 Europe PMC PMID:17027219 Europe PMC PMID:17184835 Europe PMC PMID:17299012 Europe PMC PMID:17594206 Europe PMC PMID:18030187 Europe PMC PMID:18159039 Europe PMC PMID:18162343 Europe PMC PMID:18260149 Europe PMC PMID:18361944 Europe PMC PMID:18462092 Europe PMC PMID:18582342 Europe PMC PMID:18817166 Europe PMC PMID:18983037 Europe PMC PMID:19107100 Europe PMC PMID:19830166 Europe PMC PMID:20956604 Europe PMC PMID:21109901 Europe PMC PMID:21458937 Europe PMC PMID:21466775 Europe PMC PMID:21664803 Europe PMC PMID:21719238 Europe PMC PMID:21951032 Europe PMC PMID:22011388 Europe PMC PMID:22015328 Europe PMC PMID:22027450 Europe PMC PMID:22124537 Europe PMC Reaxys:3132 Reaxys (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid IUPAC VANCOMYCIN PDBeChem Vancomycin KEGG_COMPOUND (1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid ChEBI (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):C(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine] JCBN Vancocin KEGG_DRUG vancomicin ChEBI vancomicina ChemIDplus vancomycin ChemIDplus vancomycine ChemIDplus vancomycinum ChemIDplus A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei). 0 C43H58N4O12 InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 822.94020 822.40512 CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N1CCN(C)CC1)c(O)c4c3C2=O CHEBI:26577 CHEBI:45308 CHEBI:8858 Beilstein:5723476 CAS:13292-46-1 DrugBank:DB01045 HMDB:HMDB0015179 KEGG:C06688 KEGG:D00211 PDBeChem:RFP PMID:11600355 PMID:14665784 PMID:14670633 PMID:15331348 PMID:15383168 PMID:15705662 PMID:16159084 PMID:16515773 PMID:17828712 PMID:18332862 PMID:19386087 PMID:19458074 PMID:19723399 PMID:24718527 PMID:25720500 PMID:26725427 PMID:26819743 PMID:27082586 PMID:27143080 PMID:27182275 PMID:27242224 PMID:27470132 PMID:27569735 PMID:27617596 PMID:27640793 PMID:27755552 PMID:27795624 PMID:27883163 PMID:27965540 PMID:27993874 PMID:28081169 PMID:28118809 PMID:28181840 PMID:28184157 PMID:28207542 PMID:28262820 Patent:NL6509961 Patent:US3342810 Reaxys:5723476 Wikipedia:Rifampicin (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1(4,7).0(5,28)]triaconta-1(28),1(29),2,4,9,19,21,25,27-nonaen-13-yl acetate Rifampicin chebi_ontology 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV RFP Rifampin rifamcin rifampicin rifampicina rifampicinum CHEBI:28077 rifampicin CHEBI:28077 Beilstein:5723476 Beilstein CAS:13292-46-1 ChemIDplus CAS:13292-46-1 KEGG COMPOUND PMID:11600355 Europe PMC PMID:14665784 Europe PMC PMID:14670633 Europe PMC PMID:15331348 Europe PMC PMID:15383168 Europe PMC PMID:15705662 Europe PMC PMID:16159084 Europe PMC PMID:16515773 Europe PMC PMID:17828712 Europe PMC PMID:18332862 Europe PMC PMID:19386087 Europe PMC PMID:19458074 Europe PMC PMID:19723399 Europe PMC PMID:24718527 Europe PMC PMID:25720500 Europe PMC PMID:26725427 Europe PMC PMID:26819743 Europe PMC PMID:27082586 Europe PMC PMID:27143080 Europe PMC PMID:27182275 Europe PMC PMID:27242224 Europe PMC PMID:27470132 Europe PMC PMID:27569735 Europe PMC PMID:27617596 Europe PMC PMID:27640793 Europe PMC PMID:27755552 Europe PMC PMID:27795624 Europe PMC PMID:27883163 Europe PMC PMID:27965540 Europe PMC PMID:27993874 Europe PMC PMID:28081169 Europe PMC PMID:28118809 Europe PMC PMID:28181840 Europe PMC PMID:28184157 Europe PMC PMID:28207542 Europe PMC PMID:28262820 Europe PMC Reaxys:5723476 Reaxys (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1(4,7).0(5,28)]triaconta-1(28),1(29),2,4,9,19,21,25,27-nonaen-13-yl acetate IUPAC Rifampicin KEGG_COMPOUND 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV ChemIDplus RFP DrugBank Rifampin KEGG_COMPOUND rifamcin ChEBI rifampicin KEGG_DRUG rifampicina DrugBank rifampicinum DrugBank CHEBI:10422 CHEBI:22818 KEGG:C02761 beta-L-Arabinoside chebi_ontology beta-L-arabinosides CHEBI:28079 beta-L-arabinoside CHEBI:28079 beta-L-Arabinoside KEGG_COMPOUND beta-L-arabinosides ChEBI CHEBI:1462 CHEBI:19970 KEGG:C03674 chebi_ontology 3-(carbamoyloxymethyl)cephalosporins 3-Carbamoyloxymethylcephem CHEBI:28084 3-(carbamoyloxymethyl)cephalosporin CHEBI:28084 3-(carbamoyloxymethyl)cephalosporins ChEBI 3-Carbamoyloxymethylcephem KEGG_COMPOUND 0 C18H37N5O10 InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1 SKKLOUVUUNMCJE-FQSMHNGLSA-N 483.51390 483.25404 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O CHEBI:14489 CHEBI:24948 CHEBI:24949 CHEBI:6107 Beilstein:61646 CAS:4696-76-8 Drug_Central:1520 KEGG:C00825 KEGG:D07497 KNApSAcK:C00018692 PDBeChem:9CS (1R,2S,3S,4R,6S)-4,6-diamino-3-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside Kanamycin B chebi_ontology 2'-amino-2'-deoxykanamycin Bekanamycin Nebramycin V Nebramycin factor 5 O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->6))-2-deoxy-D-streptamine CHEBI:28098 kanamycin B CHEBI:28098 Beilstein:61646 Beilstein CAS:4696-76-8 ChemIDplus CAS:4696-76-8 KEGG COMPOUND Drug_Central:1520 DrugCentral (1R,2S,3S,4R,6S)-4,6-diamino-3-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside IUPAC Kanamycin B KEGG_COMPOUND 2'-amino-2'-deoxykanamycin ChemIDplus Bekanamycin KEGG_COMPOUND Nebramycin V ChemIDplus Nebramycin factor 5 KEGG_COMPOUND O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->6))-2-deoxy-D-streptamine ChemIDplus A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica). 0 C23H22O6 InChI=1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1 JUVIOZPCNVVQFO-HBGVWJBISA-N 394.423 394.14164 [H][C@@]1(CC2=C3O[C@]4([H])COC5=C(C=C(OC)C(OC)=C5)[C@]4([H])C(=O)C3=CC=C2O1)C(C)=C CHEBI:26583 CHEBI:8897 BPDB:587 Beilstein:99070 CAS:83-79-4 DrugBank:DB11457 FooDB:FDB012837 HMDB:HMDB0034436 KEGG:C07593 KNApSAcK:C00002568 LINCS:LSM-5260 LIPID_MAPS_instance:LMPK12060007 PDBeChem:970 PMID:14976342 PMID:15043430 PMID:15790535 PMID:17077549 PMID:19013527 PMID:32972993 PMID:33402167 PMID:33901458 PMID:33961406 Patent:CN102007944 Patent:CN102090406 Reaxys:99070 VSDB:587 Wikipedia:Rotenone (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one Rotenone chebi_ontology (-)-cis-rotenone (-)-rotenone (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one 5'beta-rotenone Derris [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one barbasco canex dactinol noxfire paraderil tubatoxin CHEBI:28201 rotenone CHEBI:28201 Beilstein:99070 Beilstein CAS:83-79-4 ChemIDplus CAS:83-79-4 KEGG COMPOUND CAS:83-79-4 NIST Chemistry WebBook LIPID_MAPS_instance:LMPK12060007 LIPID MAPS PMID:14976342 Europe PMC PMID:15043430 Europe PMC PMID:15790535 Europe PMC PMID:17077549 Europe PMC PMID:19013527 Europe PMC PMID:32972993 Europe PMC PMID:33402167 Europe PMC PMID:33901458 Europe PMC PMID:33961406 Europe PMC Reaxys:99070 Reaxys (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one IUPAC Rotenone KEGG_COMPOUND (-)-cis-rotenone ChemIDplus (-)-rotenone ChemIDplus (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one ChEBI 5'beta-rotenone NIST_Chemistry_WebBook Derris ChEBI [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one NIST_Chemistry_WebBook barbasco ChemIDplus canex ChemIDplus dactinol ChemIDplus noxfire ChemIDplus paraderil ChemIDplus tubatoxin ChemIDplus A monocarboxylic acid anion that is the conjugate base of dichloroacetic acid. -1 C2HCl2O2 InChI=1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)/p-1 JXTHNDFMNIQAHM-UHFFFAOYSA-M 127.93400 126.93591 [O-]C(=O)C(Cl)Cl CHEBI:23694 Beilstein:3903873 CAS:13425-80-4 Gmelin:200685 MetaCyc:CPD-9674 PMID:21153705 Reaxys:3903873 UM-BBD_compID:c0012 dichloroacetate chebi_ontology dichloracetate dichloroacetate ion dichloroacetic acid ion(1-) CHEBI:28240 dichloroacetate CHEBI:28240 Beilstein:3903873 ChemIDplus CAS:13425-80-4 ChemIDplus Gmelin:200685 Gmelin PMID:21153705 Europe PMC Reaxys:3903873 Reaxys UM-BBD_compID:c0012 UM-BBD dichloroacetate IUPAC dichloracetate ChemIDplus dichloroacetate ion ChemIDplus dichloroacetic acid ion(1-) ChemIDplus A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine. 0 CH5N3O InChI=1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5) DUIOPKIIICUYRZ-UHFFFAOYSA-N 75.07002 75.04326 NNC(N)=O CHEBI:26644 CHEBI:9102 Beilstein:506319 CAS:57-56-7 Gmelin:100758 KEGG:C02077 MetaCyc:SEMICARBAZIDE PMID:11958526 PMID:17499072 PMID:23194563 PMID:23683401 Reaxys:506319 Wikipedia:Semicarbazide Semicarbazide hydrazinecarboxamide chebi_ontology Aminoharnstoff Aminourea Carbamidsaeurehydrazid Carbamoylhydrazine Hydrazinecarboxamide Semikarbazid carbamylhydrazine carbazamide CHEBI:28306 semicarbazide CHEBI:28306 Beilstein:506319 Beilstein CAS:57-56-7 ChemIDplus CAS:57-56-7 KEGG COMPOUND CAS:57-56-7 NIST Chemistry WebBook Gmelin:100758 Gmelin PMID:11958526 Europe PMC PMID:17499072 Europe PMC PMID:23194563 Europe PMC PMID:23683401 Europe PMC Reaxys:506319 Reaxys Semicarbazide KEGG_COMPOUND hydrazinecarboxamide IUPAC Aminoharnstoff ChEBI Aminourea KEGG_COMPOUND Carbamidsaeurehydrazid ChEBI Carbamoylhydrazine KEGG_COMPOUND Hydrazinecarboxamide KEGG_COMPOUND Semikarbazid NIST_Chemistry_WebBook carbamylhydrazine ChemIDplus carbazamide ChemIDplus A coumarin-derived antibiotic obtained from Streptomyces niveus. 0 C31H36N2O11 InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-N 612.62430 612.23191 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C CHEBI:25597 CHEBI:44505 CHEBI:7644 CAS:303-81-1 DrugBank:DB01051 Drug_Central:1974 HMDB:HMDB0015185 KEGG:C05080 KNApSAcK:C00002487 LINCS:LSM-5910 PDBeChem:NOV PMID:17132020 PMID:18418407 PMID:19282394 PMID:19762445 PMID:20325309 PMID:21388139 PMID:22897434 PMID:26844397 PMID:26926630 PMID:27829510 PMID:27914946 PMID:28246042 PMID:28316592 PMID:9687383 Patent:WO2012049521 Patent:WO2012103487 Reaxys:1445842 Novobiocin chebi_ontology N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide novobiocina novobiocine novobiocinum CHEBI:28368 novobiocin CHEBI:28368 CAS:303-81-1 ChemIDplus CAS:303-81-1 KEGG COMPOUND Drug_Central:1974 DrugCentral PMID:17132020 Europe PMC PMID:18418407 Europe PMC PMID:19282394 Europe PMC PMID:19762445 Europe PMC PMID:20325309 Europe PMC PMID:21388139 Europe PMC PMID:22897434 Europe PMC PMID:26844397 Europe PMC PMID:26926630 Europe PMC PMID:27829510 Europe PMC PMID:27914946 Europe PMC PMID:28246042 Europe PMC PMID:28316592 Europe PMC PMID:9687383 Europe PMC Reaxys:1445842 Reaxys Novobiocin KEGG_COMPOUND N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide ChEBI novobiocina DrugBank novobiocine DrugBank novobiocinum DrugBank 0 C19H37N5O7R2 447.527 447.26930 CHEBI:14294 CHEBI:24208 CHEBI:5308 CAS:11097-82-8 KEGG:C01918 chebi_ontology Gentamicin C CHEBI:28417 gentamycin C CHEBI:28417 CAS:11097-82-8 KEGG COMPOUND Gentamicin C KEGG_COMPOUND A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains. 0 C54H90N6O18 InChI=1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36+,37-,38-,39-,40+,41+,42+/m0/s1 FCFNRCROJUBPLU-DNDCDFAISA-N 1111.32180 1110.63116 CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C CHEBI:27269 CHEBI:66347 CHEBI:9924 Beilstein:78657 CAS:2001-95-8 KEGG:C06684 PMID:10603383 PMID:18633285 PMID:19347893 PMID:22683555 PMID:7590182 Reaxys:78657 Wikipedia:Valinomycin (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone Valinomycin chebi_ontology Cyclic(D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl) cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3 CHEBI:28545 valinomycin CHEBI:28545 Beilstein:78657 Beilstein Beilstein:78657 ChemIDplus CAS:2001-95-8 ChemIDplus CAS:2001-95-8 KEGG COMPOUND PMID:10603383 Europe PMC PMID:18633285 Europe PMC PMID:19347893 Europe PMC PMID:22683555 Europe PMC PMID:7590182 Europe PMC Reaxys:78657 Reaxys (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone IUPAC Valinomycin KEGG_COMPOUND Cyclic(D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl) ChemIDplus cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3 ChEBI A farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. 0 C15H26O InChI=1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3 CRDAMVZIKSXKFV-UHFFFAOYSA-N 222.36634 222.19837 [H]C(CO)=C(C)CCC([H])=C(C)CCC=C(C)C CHEBI:24013 CHEBI:24014 CHEBI:4978 Beilstein:1763926 CAS:4602-84-0 DrugBank:DB02509 HMDB:HMDB0004305 KEGG:C01493 KNApSAcK:C00003132 LINCS:LSM-5398 PMID:17640272 PMID:19402910 PMID:23902158 PMID:24987733 Reaxys:1763926 3,7,11-trimethyldodeca-2,6,10-trien-1-ol Farnesol farnesol chebi_ontology 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol 3,7,11-trimethyl-2,6,10-dodecatrienol farnesyl alcohol CHEBI:28600 farnesol CHEBI:28600 Beilstein:1763926 Beilstein CAS:4602-84-0 ChemIDplus CAS:4602-84-0 KEGG COMPOUND CAS:4602-84-0 NIST Chemistry WebBook PMID:17640272 Europe PMC PMID:19402910 Europe PMC PMID:23902158 Europe PMC PMID:24987733 Europe PMC Reaxys:1763926 Reaxys 3,7,11-trimethyldodeca-2,6,10-trien-1-ol IUPAC Farnesol KEGG_COMPOUND farnesol UniProt 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol ChemIDplus 3,7,11-trimethyl-2,6,10-dodecatrienol NIST_Chemistry_WebBook farnesyl alcohol NIST_Chemistry_WebBook A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised. 0 CH3NO2 InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4) KXDHJXZQYSOELW-UHFFFAOYSA-N 61.04006 61.01638 NC(O)=O CHEBI:22504 CHEBI:23002 CHEBI:3386 CHEBI:44573 Beilstein:1734754 CAS:463-77-4 DrugBank:DB04261 Gmelin:130345 KEGG:C01563 PDBeChem:OUT Wikipedia:Carbamic_acid CARBAMIC ACID Carbamic acid carbamic acid chebi_ontology Aminoameisensaeure Aminoformic acid Carbamate Carbamidsaeure CHEBI:28616 carbamic acid CHEBI:28616 Beilstein:1734754 Beilstein CAS:463-77-4 ChemIDplus CAS:463-77-4 KEGG COMPOUND Gmelin:130345 Gmelin CARBAMIC ACID PDBeChem Carbamic acid KEGG_COMPOUND carbamic acid IUPAC Aminoameisensaeure ChEBI Aminoformic acid KEGG_COMPOUND Carbamate KEGG_COMPOUND Carbamidsaeure ChEBI 0 P InChI=1S/P OAICVXFJPJFONN-UHFFFAOYSA-N 30.97376 30.97376 [P] CHEBI:26080 CHEBI:8168 CAS:7723-14-0 Gmelin:16235 KEGG:C06262 WebElements:P phosphorus chebi_ontology 15P P Phosphor Phosphorus fosforo phosphore phosphorus CHEBI:28659 phosphorus atom CHEBI:28659 CAS:7723-14-0 ChemIDplus CAS:7723-14-0 KEGG COMPOUND Gmelin:16235 Gmelin phosphorus IUPAC 15P IUPAC P IUPAC P KEGG_COMPOUND Phosphor ChEBI Phosphorus KEGG_COMPOUND fosforo ChEBI phosphore ChEBI phosphorus ChEBI A mixture of at least nine closely related homodetic cyclic peptides produced by Bacillus subtilis and B. licheniformis, which is particularly active against Gram-positive bacteria. C63H98N14O14S CHEBI:22684 CHEBI:2970 CAS:1405-87-4 DrugBank:DB00626 KEGG:C01667 KEGG:D00128 PMID:22114686 Wikipedia:Bacitracin Bacitracin chebi_ontology Baciim bacitracin bacitracina bacitracine bacitracins bacitracinum CHEBI:28669 bacitracin CHEBI:28669 CAS:1405-87-4 ChemIDplus CAS:1405-87-4 KEGG COMPOUND PMID:22114686 Europe PMC Bacitracin KEGG_COMPOUND Baciim KEGG_DRUG bacitracin WHO_MedNet bacitracina WHO_MedNet bacitracine WHO_MedNet bacitracins ChEBI bacitracinum WHO_MedNet 0 Cu InChI=1S/Cu RYGMFSIKBFXOCR-UHFFFAOYSA-N 63.54600 62.92960 [Cu] CHEBI:23376 CHEBI:3874 CAS:7440-50-8 Gmelin:16269 KEGG:C00070 WebElements:Cu copper chebi_ontology 29Cu Copper Cu Kupfer cobre copper cuivre cuprum CHEBI:28694 copper atom CHEBI:28694 CAS:7440-50-8 ChemIDplus CAS:7440-50-8 KEGG COMPOUND Gmelin:16269 Gmelin copper IUPAC 29Cu IUPAC Copper KEGG_COMPOUND Cu ChEBI Cu IUPAC Kupfer ChEBI cobre ChEBI copper ChEBI cuivre ChEBI cuprum IUPAC A straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger). 0 C12H26 InChI=1S/C12H26/c1-3-5-7-9-11-12-10-8-6-4-2/h3-12H2,1-2H3 SNRUBQQJIBEYMU-UHFFFAOYSA-N 170.33484 170.20345 CCCCCCCCCCCC CHEBI:25464 CHEBI:41713 CHEBI:4675 Beilstein:1697175 CAS:112-40-3 DrugBank:DB02771 Gmelin:201408 HMDB:HMDB0031444 KEGG:C08374 KNApSAcK:C00001248 LIPID_MAPS_instance:LMFA11000004 MetaCyc:CPD-9290 PDBeChem:D12 PMID:24493301 Reaxys:1697175 Wikipedia:Dodecane DODECANE Dodecane dodecane chebi_ontology Bihexyl CH3-[CH2]10-CH3 Dihexyl Dodekan n-Dodecane CHEBI:28817 dodecane CHEBI:28817 Beilstein:1697175 ChemIDplus CAS:112-40-3 ChemIDplus CAS:112-40-3 KEGG COMPOUND CAS:112-40-3 NIST Chemistry WebBook Gmelin:201408 Gmelin LIPID_MAPS_instance:LMFA11000004 LIPID MAPS PMID:24493301 Europe PMC Reaxys:1697175 Reaxys DODECANE PDBeChem Dodecane KEGG_COMPOUND dodecane IUPAC dodecane UniProt Bihexyl HMDB CH3-[CH2]10-CH3 IUPAC Dihexyl HMDB Dodekan ChEBI n-Dodecane KEGG_COMPOUND A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring. 0 C18H37N5O9 InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 NLVFBUXFDBBNBW-PBSUHMDJSA-N 467.51450 467.25913 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O CHEBI:19849 CHEBI:45933 CHEBI:9610 CAS:32986-56-4 DrugBank:DB00684 Drug_Central:2684 KEGG:C00397 KEGG:D00063 LINCS:LSM-6534 PDBeChem:TOY PMID:11000679 PMID:11072877 PMID:11459219 PMID:11478352 PMID:14961139 PMID:15813341 PMID:16205136 PMID:16239129 PMID:16478137 PMID:16650821 PMID:17150225 PMID:18331849 PMID:19072156 PMID:19220547 PMID:19340717 PMID:19465435 PMID:20000576 PMID:20884302 PMID:20938669 PMID:21275493 PMID:21343445 PMID:21357290 PMID:21396748 PMID:21414310 PMID:21429824 PMID:21438171 PMID:21530479 PMID:21592592 PMID:21726492 PMID:21756818 PMID:21796931 PMID:21815282 Reaxys:1357507 Wikipedia:Tobramycin (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside Tobramycin chebi_ontology 3'-Deoxykanamycin B Nebramycin 6 Nebramycin factir 6 O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine Tobracin (TN) Tobrex (TN) CHEBI:28864 tobramycin CHEBI:28864 CAS:32986-56-4 ChemIDplus CAS:32986-56-4 KEGG COMPOUND Drug_Central:2684 DrugCentral PMID:11000679 Europe PMC PMID:11072877 Europe PMC PMID:11459219 Europe PMC PMID:11478352 Europe PMC PMID:14961139 Europe PMC PMID:15813341 Europe PMC PMID:16205136 Europe PMC PMID:16239129 Europe PMC PMID:16478137 Europe PMC PMID:16650821 Europe PMC PMID:17150225 Europe PMC PMID:18331849 Europe PMC PMID:19072156 Europe PMC PMID:19220547 Europe PMC PMID:19340717 Europe PMC PMID:19465435 Europe PMC PMID:20000576 Europe PMC PMID:20884302 Europe PMC PMID:20938669 Europe PMC PMID:21275493 Europe PMC PMID:21343445 Europe PMC PMID:21357290 Europe PMC PMID:21396748 Europe PMC PMID:21414310 Europe PMC PMID:21429824 Europe PMC PMID:21438171 Europe PMC PMID:21530479 Europe PMC PMID:21592592 Europe PMC PMID:21726492 Europe PMC PMID:21756818 Europe PMC PMID:21796931 Europe PMC PMID:21815282 Europe PMC Reaxys:1357507 Reaxys (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside IUPAC Tobramycin KEGG_COMPOUND 3'-Deoxykanamycin B KEGG_COMPOUND Nebramycin 6 ChemIDplus Nebramycin factir 6 KEGG_COMPOUND O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine ChemIDplus Tobracin (TN) KEGG_DRUG Tobrex (TN) KEGG_DRUG A C24 straight-chain saturated fatty acid. 0 C24H48O2 InChI=1S/C24H48O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h2-23H2,1H3,(H,25,26) QZZGJDVWLFXDLK-UHFFFAOYSA-N 368.63670 368.36543 CCCCCCCCCCCCCCCCCCCCCCCC(O)=O CHEBI:25467 CHEBI:26892 CHEBI:6458 Beilstein:1728237 CAS:557-59-5 Gmelin:107095 HMDB:HMDB0002003 KEGG:C08320 KNApSAcK:C00001223 LIPID_MAPS_instance:LMFA01010024 MetaCyc:TETRACOSANOATE PMID:21781003 PMID:23019902 PMID:23157011 PMID:23394615 PMID:23871298 PMID:24491713 PMID:3174658 Reaxys:1728237 Wikipedia:Lignoceric_acid Tetracosanoic acid tetracosanoic acid chebi_ontology CH3-[CH2]22-COOH Lignoceric acid Lignozerinsaeure Tetracosansaeure n-tetracosanoic acid tetracosanic acid tetracosoic acid tetraeicosanoic acid tetraicosanoic acid CHEBI:28866 tetracosanoic acid CHEBI:28866 Beilstein:1728237 Beilstein CAS:557-59-5 ChemIDplus CAS:557-59-5 KEGG COMPOUND CAS:557-59-5 NIST Chemistry WebBook Gmelin:107095 Gmelin LIPID_MAPS_instance:LMFA01010024 LIPID MAPS PMID:21781003 Europe PMC PMID:23019902 Europe PMC PMID:23157011 Europe PMC PMID:23394615 Europe PMC PMID:23871298 Europe PMC PMID:24491713 Europe PMC PMID:3174658 Europe PMC Reaxys:1728237 Reaxys Tetracosanoic acid KEGG_COMPOUND tetracosanoic acid IUPAC CH3-[CH2]22-COOH IUPAC Lignoceric acid KEGG_COMPOUND Lignozerinsaeure ChEBI Tetracosansaeure ChEBI n-tetracosanoic acid ChEBI tetracosanic acid ChEBI tetracosoic acid ChEBI tetraeicosanoic acid ChEBI tetraicosanoic acid ChEBI The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid. -1 CO2R 44.00950 43.98983 [O-]C([*])=O CHEBI:13634 CHEBI:24022 CHEBI:4985 KEGG:C02403 PMID:18628202 Fatty acid anion chebi_ontology Alkanate Fettsaeureanion Fettsaeureanionen a fatty acid acido graso anionico acidos grasos anionicos anion de l'acide gras fatty acid anions CHEBI:28868 fatty acid anion CHEBI:28868 PMID:18628202 Europe PMC Fatty acid anion KEGG_COMPOUND Alkanate KEGG_COMPOUND Fettsaeureanion ChEBI Fettsaeureanionen ChEBI a fatty acid UniProt acido graso anionico ChEBI acidos grasos anionicos ChEBI anion de l'acide gras ChEBI fatty acid anions ChEBI An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide. 0 C13H13Cl2N3O3 InChI=1S/C13H13Cl2N3O3/c1-7(2)16-12(20)17-6-11(19)18(13(17)21)10-4-8(14)3-9(15)5-10/h3-5,7H,6H2,1-2H3,(H,16,20) ONUFESLQCSAYKA-UHFFFAOYSA-N 330.16700 329.03340 CC(C)NC(=O)N1CC(=O)N(C1=O)c1cc(Cl)cc(Cl)c1 CHEBI:24871 CHEBI:8902 Beilstein:895003 CAS:36734-19-7 HMDB:HMDB0031795 KEGG:C11208 PMID:11451425 PMID:22115616 PMID:22262495 PPDB:403 Patent:CN103053579 Patent:CN103392726 Patent:DE2149923 Patent:US3755350 Pesticides:iprodione Reaxys:895003 UM-BBD_compID:c0635 Wikipedia:Iprodione 3-(3,5-dichlorophenyl)-2,4-dioxo-N-(propan-2-yl)-imidazolidine-1-carboxamide Iprodione chebi_ontology 3-(3,5-dichlorophenyl)-1-(1-methylethyl)carbamoylhydantoin 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxoimidazolidine-1-carboxamide 3-(3,5-dichlorophenyl)-N-isopropyl-2,4-dioxoimidazolidine-1-carboxamide 3-(3,5-dichlorophenyl)hydantoin-1-carboxylic acid isopropylamide Rovral Rovrol CHEBI:28909 iprodione CHEBI:28909 Beilstein:895003 Beilstein CAS:36734-19-7 ChemIDplus CAS:36734-19-7 KEGG COMPOUND CAS:36734-19-7 NIST Chemistry WebBook PMID:11451425 Europe PMC PMID:22115616 Europe PMC PMID:22262495 Europe PMC Pesticides:iprodione Alan Wood's Pesticides Reaxys:895003 Reaxys UM-BBD_compID:c0635 UM-BBD 3-(3,5-dichlorophenyl)-2,4-dioxo-N-(propan-2-yl)-imidazolidine-1-carboxamide IUPAC Iprodione KEGG_COMPOUND 3-(3,5-dichlorophenyl)-1-(1-methylethyl)carbamoylhydantoin NIST_Chemistry_WebBook 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide ChemIDplus 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide UM-BBD 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxoimidazolidine-1-carboxamide IUPAC 3-(3,5-dichlorophenyl)-N-isopropyl-2,4-dioxoimidazolidine-1-carboxamide ChemIDplus 3-(3,5-dichlorophenyl)hydantoin-1-carboxylic acid isopropylamide ChemIDplus Rovral ChEBI Rovral KEGG_COMPOUND Rovrol KEGG_COMPOUND A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus. 0 C3H7O4P InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1 YMDXZJFXQJVXBF-STHAYSLISA-N 138.05900 138.00820 C[C@@H]1O[C@@H]1P(O)(O)=O CHEBI:24100 CHEBI:42503 CHEBI:8159 CAS:23155-02-4 DrugBank:DB00828 Drug_Central:1243 KEGG:C06454 KEGG:D04253 KNApSAcK:C00000789 MetaCyc:CPD0-1113 PDBeChem:FCN PMID:105327 PMID:17124631 PMID:19308743 PMID:2660079 PMID:288976 PMID:3464490 PMID:3900889 PMID:488578 PMID:614140 PMID:6348659 PMID:6796449 PMID:7030849 PMID:7224844 PMID:740308 PMID:9309262 Reaxys:1680831 FOSFOMYCIN [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid chebi_ontology (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid (1R,2S)-epoxypropylphosphonic acid (2R-cis)-(3-Methyloxiranyl)phosphonic acid 1R-cis-(1,2-epoxypropyl)phosphonic acid FCM L-cis-1,2-epoxypropylphosphonic acid Phosphomycin Phosphonomycin cis-(1R,2S)-epoxypropylphosphonic acid fosfomicina fosfomycin fosfomycine fosfomycinum phosphonemycin CHEBI:28915 fosfomycin CHEBI:28915 CAS:23155-02-4 ChemIDplus CAS:23155-02-4 KEGG COMPOUND Drug_Central:1243 DrugCentral PMID:105327 Europe PMC PMID:17124631 Europe PMC PMID:19308743 Europe PMC PMID:2660079 Europe PMC PMID:288976 Europe PMC PMID:3464490 Europe PMC PMID:3900889 Europe PMC PMID:488578 Europe PMC PMID:614140 Europe PMC PMID:6348659 Europe PMC PMID:6796449 Europe PMC PMID:7030849 Europe PMC PMID:7224844 Europe PMC PMID:740308 Europe PMC PMID:9309262 Europe PMC Reaxys:1680831 Reaxys FOSFOMYCIN PDBeChem [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid IUPAC (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid ChemIDplus (1R,2S)-epoxypropylphosphonic acid MetaCyc (2R-cis)-(3-Methyloxiranyl)phosphonic acid ChemIDplus 1R-cis-(1,2-epoxypropyl)phosphonic acid ChEBI FCM KEGG_DRUG L-cis-1,2-epoxypropylphosphonic acid MetaCyc Phosphomycin ChemIDplus Phosphonomycin KEGG_COMPOUND cis-(1R,2S)-epoxypropylphosphonic acid MetaCyc fosfomicina ChemIDplus fosfomycin KEGG_DRUG fosfomycine ChemIDplus fosfomycinum ChemIDplus phosphonemycin MetaCyc An onium cation obtained by protonation of ammonia. +1 H4N InChI=1S/H3N/h1H3/p+1 QGZKDVFQNNGYKY-UHFFFAOYSA-O 18.03850 18.03383 [H][N+]([H])([H])[H] CHEBI:22534 CHEBI:49783 CHEBI:7435 CAS:14798-03-9 Gmelin:84 KEGG:C01342 MetaCyc:AMMONIUM MolBase:929 PDBeChem:NH4 PMID:11319011 PMID:11341317 PMID:12096804 PMID:14512268 PMID:14879753 PMID:16345391 PMID:16903292 PMID:17392693 PMID:18515490 PMID:19199063 PMID:19596600 PMID:19682559 PMID:19716251 PMID:21993530 PMID:22265469 PMID:22524020 PMID:22562341 PMID:22631217 Reaxys:16093784 Wikipedia:Ammonium ammonium azanium chebi_ontology Ammonium(1+) NH4(+) NH4+ [NH4](+) ammonium cation ammonium ion CHEBI:28938 ammonium CHEBI:28938 CAS:14798-03-9 ChemIDplus CAS:14798-03-9 NIST Chemistry WebBook Gmelin:84 Gmelin PMID:11319011 Europe PMC PMID:11341317 Europe PMC PMID:12096804 Europe PMC PMID:14512268 Europe PMC PMID:14879753 Europe PMC PMID:16345391 Europe PMC PMID:16903292 Europe PMC PMID:17392693 Europe PMC PMID:18515490 Europe PMC PMID:19199063 Europe PMC PMID:19596600 Europe PMC PMID:19682559 Europe PMC PMID:19716251 Europe PMC PMID:21993530 Europe PMC PMID:22265469 Europe PMC PMID:22524020 Europe PMC PMID:22562341 Europe PMC PMID:22631217 Europe PMC Reaxys:16093784 Reaxys ammonium ChEBI ammonium IUPAC azanium IUPAC Ammonium(1+) ChemIDplus NH4(+) IUPAC NH4(+) UniProt NH4+ KEGG_COMPOUND [NH4](+) MolBase ammonium cation ChemIDplus ammonium ion PDBeChem Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. CHEBI:22481 CHEBI:22530 CHEBI:2662 KEGG:C05383 PMID:18424273 PMID:9056391 chebi_ontology Aminosugars amino sugars aminosugar CHEBI:28963 amino sugar CHEBI:28963 PMID:18424273 Europe PMC PMID:9056391 Europe PMC Aminosugars KEGG_COMPOUND amino sugars ChEBI aminosugar ChEBI A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid. -2 C2O4R 88.019 87.97966 [O-]C(=O)[*]C([O-])=O CHEBI:13632 CHEBI:23688 CHEBI:23689 CHEBI:38711 dicarboxylic acid dianion chebi_ontology a dicarboxylate dicarboxylate dicarboxylates dicarboxylic acid dianions CHEBI:28965 dicarboxylic acid dianion CHEBI:28965 dicarboxylic acid dianion ChEBI a dicarboxylate UniProt dicarboxylate ChEBI dicarboxylates ChEBI dicarboxylic acid dianions ChEBI A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. 0 C16H19N3O4S InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1 AVKUERGKIZMTKX-NJBDSQKTSA-N 349.40500 349.10963 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O CHEBI:22536 CHEBI:2683 CHEBI:40648 CHEBI:45042 Beilstein:4300240 CAS:69-53-4 DrugBank:DB00415 Drug_Central:198 HMDB:HMDB0014559 KEGG:C06574 KEGG:D00204 LINCS:LSM-5761 PDB:1H8S PDBeChem:AIC PDBeChem:PN1 PMID:10930630 PMID:12562703 PMID:12569987 PMID:12833570 PMID:14139119 PMID:14455820 PMID:15768449 PMID:16033609 PMID:18611716 PMID:19967069 PMID:2083978 PMID:23568176 PMID:23861268 PMID:24474427 PMID:24666465 PMID:25998949 PMID:28543395 PMID:29017833 PMID:6176550 PMID:8020088 PMID:9433938 Patent:GB902703 Patent:US2985648 Patent:US3157640 Reaxys:4300240 VSDB:1849 Wikipedia:Ampicillin 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid Ampicillin chebi_ontology (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ABPC AMP AP Anhydrous ampicillin D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid D-(-)-ampicillin aminobenzylpenicillin ampicilina ampicillin ampicillin acid ampicillin anhydrous ampicilline ampicillinum CHEBI:28971 ampicillin CHEBI:28971 Beilstein:4300240 Beilstein CAS:69-53-4 ChemIDplus Drug_Central:198 DrugCentral PMID:10930630 Europe PMC PMID:12562703 Europe PMC PMID:12569987 Europe PMC PMID:12833570 Europe PMC PMID:14139119 Europe PMC PMID:14455820 Europe PMC PMID:15768449 Europe PMC PMID:16033609 Europe PMC PMID:18611716 Europe PMC PMID:19967069 Europe PMC PMID:2083978 Europe PMC PMID:23568176 Europe PMC PMID:23861268 Europe PMC PMID:24474427 Europe PMC PMID:24666465 Europe PMC PMID:25998949 Europe PMC PMID:28543395 Europe PMC PMID:29017833 Europe PMC PMID:6176550 Europe PMC PMID:8020088 Europe PMC PMID:9433938 Europe PMC Reaxys:4300240 Reaxys 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC Ampicillin KEGG_COMPOUND (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID PDBeChem (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC (2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid PDBeChem 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid ChemIDplus ABPC ChEBI AMP ChEBI AP ChEBI Anhydrous ampicillin KEGG_COMPOUND D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid ChemIDplus D-(-)-ampicillin ChemIDplus aminobenzylpenicillin DrugBank ampicilina ChemIDplus ampicillin ChemIDplus ampicillin acid DrugBank ampicillin anhydrous DrugBank ampicilline ChemIDplus ampicillinum ChemIDplus 0 CH2O3 InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4) BVKZGUZCCUSVTD-UHFFFAOYSA-N 62.02478 62.00039 OC(O)=O CHEBI:13351 CHEBI:23017 CHEBI:23744 CHEBI:3401 CAS:463-79-6 Gmelin:25554 KEGG:C01353 PDBeChem:CO3 Carbonic acid carbonic acid dihydroxidooxidocarbon chebi_ontology Dihydrogen carbonate H2CO3 Koehlensaeure [CO(OH)2] CHEBI:28976 carbonic acid CHEBI:28976 CAS:463-79-6 ChemIDplus CAS:463-79-6 KEGG COMPOUND Gmelin:25554 Gmelin Carbonic acid KEGG_COMPOUND carbonic acid IUPAC dihydroxidooxidocarbon IUPAC Dihydrogen carbonate KEGG_COMPOUND H2CO3 IUPAC H2CO3 KEGG_COMPOUND Koehlensaeure ChEBI [CO(OH)2] IUPAC A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups. 0 C18H18N8O7S3 InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1 VAAUVRVFOQPIGI-SPQHTLEESA-N 554.58000 554.04606 [H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O CHEBI:23059 CHEBI:3513 CHEBI:446214 Beilstein:6495519 CAS:73384-59-5 DrugBank:DB01212 Drug_Central:564 HMDB:HMDB0015343 KEGG:C06683 KEGG:D07659 MetaCyc:CPD-12294 PMID:11067716 PMID:11285492 PMID:11431418 PMID:11432680 PMID:11529382 PMID:11605716 PMID:11642230 PMID:11760218 PMID:11815759 PMID:11856984 PMID:11875753 PMID:11985490 PMID:12146884 PMID:12426628 PMID:12569987 PMID:12711894 PMID:12797390 PMID:12830336 PMID:12833570 PMID:12868545 PMID:1384868 PMID:15091234 PMID:15106316 PMID:15225244 PMID:15499067 PMID:15828439 PMID:15846537 PMID:15880392 PMID:15886468 PMID:16082406 PMID:16118675 PMID:16161754 PMID:16185184 PMID:16602117 PMID:16640341 PMID:16734965 PMID:17129840 PMID:17173674 PMID:17216959 PMID:17226043 PMID:17347554 PMID:17367972 PMID:17592517 PMID:18246742 PMID:18473104 PMID:18484523 PMID:18611641 PMID:18676229 PMID:18773080 PMID:18977704 PMID:19008722 PMID:19367098 PMID:19423473 PMID:19496200 PMID:19625514 PMID:19649758 PMID:21425867 PMID:29017833 Patent:GB2022090 Patent:US4327210 Reaxys:6495519 Wikipedia:Ceftriaxone 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ceftriaxona ceftriaxone ceftriaxonum rocephin CHEBI:29007 ceftriaxone CHEBI:29007 Beilstein:6495519 Beilstein CAS:73384-59-5 ChemIDplus CAS:73384-59-5 KEGG COMPOUND CAS:73384-59-5 KEGG DRUG Drug_Central:564 DrugCentral PMID:11067716 Europe PMC PMID:11285492 Europe PMC PMID:11431418 Europe PMC PMID:11432680 Europe PMC PMID:11529382 Europe PMC PMID:11605716 Europe PMC PMID:11642230 Europe PMC PMID:11760218 Europe PMC PMID:11815759 Europe PMC PMID:11856984 Europe PMC PMID:11875753 Europe PMC PMID:11985490 Europe PMC PMID:12146884 Europe PMC PMID:12426628 Europe PMC PMID:12569987 Europe PMC PMID:12711894 Europe PMC PMID:12797390 Europe PMC PMID:12830336 Europe PMC PMID:12833570 Europe PMC PMID:12868545 Europe PMC PMID:1384868 Europe PMC PMID:15091234 Europe PMC PMID:15106316 Europe PMC PMID:15225244 Europe PMC PMID:15499067 Europe PMC PMID:15828439 Europe PMC PMID:15846537 Europe PMC PMID:15880392 Europe PMC PMID:15886468 Europe PMC PMID:16082406 Europe PMC PMID:16118675 Europe PMC PMID:16161754 Europe PMC PMID:16185184 Europe PMC PMID:16602117 Europe PMC PMID:16640341 ChEMBL PMID:16734965 Europe PMC PMID:17129840 Europe PMC PMID:17173674 Europe PMC PMID:17216959 Europe PMC PMID:17226043 Europe PMC PMID:17347554 Europe PMC PMID:17367972 Europe PMC PMID:17592517 Europe PMC PMID:18246742 Europe PMC PMID:18473104 Europe PMC PMID:18484523 Europe PMC PMID:18611641 Europe PMC PMID:18676229 Europe PMC PMID:18773080 Europe PMC PMID:18977704 Europe PMC PMID:19008722 Europe PMC PMID:19367098 Europe PMC PMID:19423473 Europe PMC PMID:19496200 Europe PMC PMID:19625514 Europe PMC PMID:19649758 Europe PMC PMID:21425867 Europe PMC PMID:29017833 Europe PMC Reaxys:6495519 Reaxys 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid IUPAC (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC ceftriaxona ChemIDplus ceftriaxone KEGG_DRUG ceftriaxonum ChemIDplus rocephin ChEBI A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. 0 C31H48O6 InChI=1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1 IECPWNUMDGFDKC-MZJAQBGESA-N 516.70920 516.34509 [H][C@@]12CC[C@@]3(C)[C@@]([H])([C@H](O)C[C@@]4([H])\C([C@H](C[C@]34C)OC(C)=O)=C(/CCC=C(C)C)C(O)=O)[C@@]1(C)CC[C@@H](O)[C@H]2C CHEBI:24133 CHEBI:42742 CHEBI:5201 Beilstein:2197692 Beilstein:5672885 CAS:6990-06-3 DrugBank:DB02703 Drug_Central:1261 HMDB:HMDB0015570 KEGG:C06694 KEGG:D04281 KNApSAcK:C00023903 LIPID_MAPS_instance:LMPR0106040001 MetaCyc:CPD0-1606 PDBeChem:FUA PMID:11412963 PMID:12937375 PMID:13899435 PMID:13996455 PMID:15843024 PMID:17082187 PMID:20797618 PMID:22066960 PMID:22100514 PMID:22197537 PMID:22290345 PMID:22308410 PMID:22354299 PMID:22612900 PMID:22645663 PMID:22888356 PMID:23102978 PMID:23114758 PMID:23147726 PMID:8624493 Reaxys:2197692 VSDB:1776 Wikipedia:Fusidic_acid (2Z)-2-[(17Z)-16beta-acetoxy-3alpha,11alpha-dihydroxy-4alpha,8alpha,10,14beta-tetramethyl-5alpha,9beta,13alpha-gonan-17-ylidene]-6-methylhept-5-enoic acid Fusidic acid chebi_ontology Fucidin acid Fusidine Ramycin fucidic acid CHEBI:29013 fusidic acid CHEBI:29013 Beilstein:2197692 Beilstein Beilstein:5672885 Beilstein CAS:6990-06-3 ChemIDplus Drug_Central:1261 DrugCentral LIPID_MAPS_instance:LMPR0106040001 LIPID MAPS PMID:11412963 Europe PMC PMID:12937375 Europe PMC PMID:13899435 Europe PMC PMID:13996455 Europe PMC PMID:15843024 Europe PMC PMID:17082187 Europe PMC PMID:20797618 Europe PMC PMID:22066960 Europe PMC PMID:22100514 Europe PMC PMID:22197537 Europe PMC PMID:22290345 Europe PMC PMID:22308410 Europe PMC PMID:22354299 Europe PMC PMID:22612900 Europe PMC PMID:22645663 Europe PMC PMID:22888356 Europe PMC PMID:23102978 Europe PMC PMID:23114758 Europe PMC PMID:23147726 Europe PMC PMID:8624493 Europe PMC Reaxys:2197692 Reaxys (2Z)-2-[(17Z)-16beta-acetoxy-3alpha,11alpha-dihydroxy-4alpha,8alpha,10,14beta-tetramethyl-5alpha,9beta,13alpha-gonan-17-ylidene]-6-methylhept-5-enoic acid IUPAC Fusidic acid KEGG_COMPOUND Fucidin acid ChemIDplus Fusidine ChemIDplus Ramycin ChemIDplus fucidic acid ChEBI An ion of copper carrying a double positive charge. +2 Cu InChI=1S/Cu/q+2 JPVYNHNXODAKFH-UHFFFAOYSA-N 63.54600 62.92850 [Cu++] CHEBI:20882 CHEBI:23380 CHEBI:49550 CAS:15158-11-9 Gmelin:6855 PDBeChem:CU PMID:23900424 PMID:24168430 Reaxys:3587177 copper(2+) copper(2+) ion copper(II) cation chebi_ontology COPPER (II) ION Cu(2+) Cu(II) Cu2+ copper(II) cation copper, ion (Cu2+) cupric ion CHEBI:29036 copper(2+) CHEBI:29036 CAS:15158-11-9 ChemIDplus Gmelin:6855 Gmelin PMID:23900424 Europe PMC PMID:24168430 Europe PMC Reaxys:3587177 Reaxys copper(2+) IUPAC copper(2+) ion IUPAC copper(II) cation IUPAC COPPER (II) ION PDBeChem Cu(2+) UniProt Cu(II) ChEBI Cu2+ ChEBI copper(II) cation ChEBI copper, ion (Cu2+) ChemIDplus cupric ion ChEBI The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. -1 CO2R 44.00950 43.98983 [O-]C([*])=O CHEBI:13626 CHEBI:13945 CHEBI:23026 CHEBI:58657 chebi_ontology a carboxylate carboxylic acid anions carboxylic anions CHEBI:29067 carboxylic acid anion CHEBI:29067 a carboxylate UniProt carboxylic acid anions ChEBI carboxylic anions ChEBI A monoatomic monocation obtained from sodium. +1 Na InChI=1S/Na/q+1 FKNQFGJONOIPTF-UHFFFAOYSA-N 22.98977 22.98922 [Na+] CHEBI:26717 CHEBI:49766 CHEBI:9175 CAS:17341-25-2 Gmelin:15196 KEGG:C01330 PDBeChem:NA sodium cation sodium(1+) sodium(1+) ion sodium(I) cation chebi_ontology Na(+) Na+ SODIUM ION CHEBI:29101 sodium(1+) CHEBI:29101 CAS:17341-25-2 ChemIDplus CAS:17341-25-2 NIST Chemistry WebBook Gmelin:15196 Gmelin sodium cation IUPAC sodium(1+) IUPAC sodium(1+) ion IUPAC sodium(I) cation IUPAC Na(+) IUPAC Na(+) UniProt Na+ KEGG_COMPOUND SODIUM ION PDBeChem A monoatomic monocation obtained from potassium. +1 K InChI=1S/K/q+1 NPYPAHLBTDXSSS-UHFFFAOYSA-N 39.09830 38.96316 [K+] CHEBI:26219 CHEBI:49685 CHEBI:8345 CAS:24203-36-9 Gmelin:15203 KEGG:C00238 KEGG:D08403 PDBeChem:K potassium cation potassium(1+) potassium(1+) ion potassium(I) cation chebi_ontology K(+) K+ POTASSIUM ION CHEBI:29103 potassium(1+) CHEBI:29103 CAS:24203-36-9 NIST Chemistry WebBook Gmelin:15203 Gmelin potassium cation IUPAC potassium(1+) IUPAC potassium(1+) ion IUPAC potassium(I) cation IUPAC K(+) IUPAC K(+) UniProt K+ KEGG_COMPOUND POTASSIUM ION PDBeChem -1 HO2 InChI=1S/H2O2/c1-2/h1-2H/p-1 MHAJPDPJQMAIIY-UHFFFAOYSA-M 33.00674 32.99820 [H]O[O-] CAS:14691-59-9 Gmelin:507 dioxidanide hydrogen(peroxide)(1-) hydrogendioxide(1-) hydrogenperoxide(1-) chebi_ontology HO2(-) HOO anion HOO(-) [HO2](-) CHEBI:29192 hydrogenperoxide(1-) CHEBI:29192 CAS:14691-59-9 ChemIDplus CAS:14691-59-9 NIST Chemistry WebBook Gmelin:507 Gmelin dioxidanide IUPAC hydrogen(peroxide)(1-) IUPAC hydrogendioxide(1-) IUPAC hydrogenperoxide(1-) IUPAC HO2(-) IUPAC HOO anion NIST_Chemistry_WebBook HOO(-) ChEBI [HO2](-) ChEBI 0 H2O3S InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3) BDHFUVZGWQCTTF-UHFFFAOYSA-N 82.08008 81.97247 [H]S(O)(=O)=O Gmelin:1404640 hydridohydroxidodioxidosulfur sulfonic acid chebi_ontology HSHO3 Sulfonsaeure [SHO2(OH)] acide sulfonique sulphonic acid CHEBI:29214 sulfonic acid CHEBI:29214 Gmelin:1404640 Gmelin hydridohydroxidodioxidosulfur IUPAC sulfonic acid IUPAC HSHO3 IUPAC Sulfonsaeure ChEBI [SHO2(OH)] IUPAC acide sulfonique ChEBI sulphonic acid ChEBI An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety. 0 HSR 33.07300 32.97990 S[*] CHEBI:13443 CHEBI:13696 CHEBI:17366 CHEBI:26969 CHEBI:8766 CHEBI:9556 KEGG:C00145 Wikipedia:Thiol Thiol thiols chebi_ontology Mercaptan Merkaptan RSH a thiol mercaptans thiols CHEBI:29256 thiol CHEBI:29256 Thiol KEGG_COMPOUND thiols IUPAC Mercaptan KEGG_COMPOUND Merkaptan ChEBI RSH IUPAC a thiol UniProt mercaptans ChEBI thiols ChEBI A monovalent inorganic anion obtained by deprotonation of phosphorous acid. -1 H2O3P InChI=1S/H2O3P/c1-4(2)3/h1-2H/q-1 BLBIZNCSZLTDPW-UHFFFAOYSA-N 80.98784 80.97470 [H]OP([O-])O[H] Gmelin:558293 dihydrogen(trioxidophosphate)(1-) dihydrogenphosphite dihydroxidooxidophosphate(1-) chebi_ontology H2PO3(-) [PO(OH)2] (-) dihydrogen phosphite CHEBI:29258 dihydrogenphosphite CHEBI:29258 Gmelin:558293 Gmelin dihydrogen(trioxidophosphate)(1-) IUPAC dihydrogenphosphite IUPAC dihydroxidooxidophosphate(1-) IUPAC H2PO3(-) IUPAC [PO(OH)2] (-) IUPAC dihydrogen phosphite ChEBI A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid. -2 HO3P InChI=1S/HO3P/c1-4(2)3/h1H/q-2 GBHRVZIGDIUCJB-UHFFFAOYSA-N 79.97990 79.96743 [H]OP([O-])[O-] Gmelin:323302 hydrogen(trioxidophosphate)(2-) hydrogenphosphite hydroxidodioxidophosphate(2-) chebi_ontology HPO3(2-) [PO2(OH)](2-) hydrogen phosphite CHEBI:29259 hydrogenphosphite CHEBI:29259 Gmelin:323302 Gmelin hydrogen(trioxidophosphate)(2-) IUPAC hydrogenphosphite IUPAC hydroxidodioxidophosphate(2-) IUPAC HPO3(2-) IUPAC [PO2(OH)](2-) IUPAC hydrogen phosphite IUPAC -2 N2 InChI=1S/N2/c1-2/q-2 BZZJUZUZJRQHLZ-UHFFFAOYSA-N 28.01348 28.00725 [N-]=[N-] Gmelin:1565041 diazenediide dinitride(2-) chebi_ontology N2(2-) CHEBI:29277 dinitride(2-) CHEBI:29277 Gmelin:1565041 Gmelin diazenediide IUPAC dinitride(2-) IUPAC N2(2-) IUPAC CHEBI:13810 CHEBI:22325 CHEBI:2583 chebi_ontology alkyl sulfates CHEBI:29281 alkyl sulfate CHEBI:29281 alkyl sulfates ChEBI -1 H2N InChI=1S/H2N/h1H2/q-1 HYGWNUKOUCZBND-UHFFFAOYSA-N 16.02262 16.01927 [H][N-][H] amide azanide dihydridonitrate(1-) chebi_ontology NH2(-) CHEBI:29337 azanide CHEBI:29337 amide IUPAC azanide IUPAC dihydridonitrate(1-) IUPAC NH2(-) IUPAC A divalent inorganic anion resulting from the removal of two protons from ammonia. -2 HN InChI=1S/HN/h1H/q-2 DZQYTNGKSBCIOE-UHFFFAOYSA-N 15.01468 15.01200 [N--][H] azanediide hydridonitrate(2-) chebi_ontology NH(2-) imide CHEBI:29340 hydridonitrate(2-) CHEBI:29340 azanediide IUPAC hydridonitrate(2-) IUPAC NH(2-) IUPAC imide IUPAC A carboxamide derived from a monocarboxylic acid. 0 CNOR3 42.01680 41.99799 [*]N([*])C([*])=O CHEBI:13211 CHEBI:22207 CHEBI:25383 CHEBI:6977 chebi_ontology monocarboxylic acid amides CHEBI:29347 monocarboxylic acid amide CHEBI:29347 monocarboxylic acid amides ChEBI 0 O2 31.99880 31.98983 O(O*)* peroxy chebi_ontology -OO- CHEBI:29369 peroxy group CHEBI:29369 peroxy IUPAC -OO- IUPAC 0 C48H72O14 InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 873.07690 872.49221 CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C4/CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)C=C[C@@H]1C BPDB:8 Beilstein:3645625 CAS:65195-55-3 KEGG:C11983 LIPID_MAPS_instance:LMPK04000024 MetaCyc:CPD-12963 VSDB:8 (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside Avermectin B1a chebi_ontology abamectin component B1a CHEBI:29534 avermectin B1a CHEBI:29534 Beilstein:3645625 Beilstein CAS:65195-55-3 ChemIDplus CAS:65195-55-3 KEGG COMPOUND LIPID_MAPS_instance:LMPK04000024 LIPID MAPS (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside IUPAC Avermectin B1a KEGG_COMPOUND abamectin component B1a ChemIDplus 0 C47H70O14 InChI=1S/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1 ZFUKERYTFURFGA-PVVXTEPVSA-N 859.05030 858.47656 [H][C@@]12C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(O2)O[C@]([H])(C(C)C)[C@@H](C)C=C1)[C@]34O Beilstein:8399072 CAS:65195-56-4 KEGG:C11967 LIPID_MAPS_instance:LMPK04000020 MetaCyc:CPD-12964 (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside Avermectin B1b chebi_ontology (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside abamectin component B1b CHEBI:29537 avermectin B1b CHEBI:29537 Beilstein:8399072 Beilstein CAS:65195-56-4 ChemIDplus CAS:65195-56-4 KEGG COMPOUND LIPID_MAPS_instance:LMPK04000020 LIPID MAPS (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside IUPAC Avermectin B1b KEGG_COMPOUND (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside IUPAC abamectin component B1b ChemIDplus A macrolide antibiotic useful for the treatment of bacterial infections. 0 C38H72N2O12 InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 MQTOSJVFKKJCRP-BICOPXKESA-N 748.98450 748.50853 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O CHEBI:46596 Beilstein:5387583 CAS:83905-01-5 DrugBank:DB00207 Drug_Central:276 HMDB:HMDB0014352 KEGG:C06838 KEGG:D07486 LINCS:LSM-5821 PDBeChem:ZIT PMID:15143799 PMID:18253999 Patent:BE892357 Patent:US4517359 Reaxys:5387583 Reaxys:8820027 Wikipedia:Azithromycin (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside chebi_ontology (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one Azenil Azifast Azigram Azimakrol Azitromin Hemomycin Zithromax Zmax azithromycine azithromycinum azitromicina CHEBI:2955 azithromycin CHEBI:2955 Beilstein:5387583 Beilstein CAS:83905-01-5 ChemIDplus Drug_Central:276 DrugCentral PMID:15143799 Europe PMC PMID:18253999 Europe PMC Reaxys:5387583 Reaxys Reaxys:8820027 Reaxys (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside IUPAC (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one ChemIDplus Azenil DrugBank Azifast ChEBI Azigram ChEBI Azimakrol ChEBI Azitromin ChEBI Hemomycin DrugBank Zithromax DrugBank Zmax DrugBank azithromycine ChemIDplus azithromycinum ChemIDplus azitromicina WHO_MedNet A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. 0 CAS:61036-62-2 DrugBank:DB06149 KEGG:C15820 KEGG:D02142 PMID:1416858 PMID:24506456 PMID:24693468 PMID:25190719 PMID:25218156 PMID:25224001 PMID:25358800 PMID:25616054 PMID:25726436 Reaxys:8196734 Wikipedia:Teicoplanin chebi_ontology Targocid antibiotic 8327A teicoplanin teicoplanina teicoplanine teicoplaninum CHEBI:29687 teicoplanin CHEBI:29687 CAS:61036-62-2 ChemIDplus CAS:61036-62-2 KEGG DRUG PMID:1416858 Europe PMC PMID:24506456 Europe PMC PMID:24693468 Europe PMC PMID:25190719 Europe PMC PMID:25218156 Europe PMC PMID:25224001 Europe PMC PMID:25358800 Europe PMC PMID:25616054 Europe PMC PMID:25726436 Europe PMC Reaxys:8196734 Reaxys Targocid KEGG_DRUG antibiotic 8327A ChemIDplus teicoplanin ChemIDplus teicoplanina ChemIDplus teicoplanine WHO_MedNet teicoplaninum ChemIDplus 0 C43H65N5O10 InChI=1S/C43H65N5O10/c1-12-33-43(8)37(48(41(53)58-43)19-14-13-18-47-23-31(45-24-47)30-16-15-17-44-22-30)27(4)34(49)25(2)21-42(7,54-11)38(28(5)35(50)29(6)39(52)56-33)57-40-36(51)32(46(9)10)20-26(3)55-40/h15-17,22-29,32-33,36-38,40,51H,12-14,18-21H2,1-11H3/t25-,26-,27+,28+,29+,32+,33-,36-,37-,38-,40+,42-,43-/m1/s1 LJVAJPDWBABPEJ-MMEUOAQYSA-N 812.00390 811.47314 C[C@@]12[C@](N(C(O1)=O)CCCCN3C=C(N=C3)C=4C=CC=NC4)([C@@H](C)C(=O)[C@H](C)C[C@](OC)(C)[C@@H]([C@H](C([C@](C(O[C@@H]2CC)=O)(C)[H])=O)C)O[C@]5([C@H](O)[C@@H](N(C)C)C[C@H](O5)C)[H])[H] CHEBI:46029 CAS:191114-48-4 Drug_Central:2581 KEGG:C12009 KEGG:D01078 PDBeChem:TEL TELITHROMYCIN Telithromycin chebi_ontology (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside HMR 3647 HMR-3647 HMR3647 RU 66647 RU-66647 RU66647 CHEBI:29688 telithromycin CHEBI:29688 CAS:191114-48-4 KEGG COMPOUND Drug_Central:2581 DrugCentral TELITHROMYCIN PDBeChem Telithromycin KEGG_COMPOUND (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-1-[4-(4-pyridin-3-yl-1H-imidazol-1-yl)butyl]tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside PDBeChem HMR 3647 DrugCentral HMR-3647 KEGG_COMPOUND HMR3647 KEGG_COMPOUND RU 66647 DrugCentral RU-66647 KEGG_COMPOUND RU66647 KEGG_COMPOUND A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety. 0 C25H38N4O16 650.587 650.22828 [H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O CAS:11089-65-9 KEGG:C12063 PMID:11478581 PMID:11514096 PMID:11732194 PMID:11798249 PMID:12093793 PMID:12106388 PMID:12136966 PMID:12232600 PMID:12232799 PMID:12515321 PMID:160437 PMID:1624425 PMID:3018444 PMID:315774 PMID:34700340 PMID:34979291 PMID:35233582 PMID:35370192 PMID:4624615 PMID:4630978 PMID:5103138 PMID:5103535 PMID:5168706 PMID:6153524 PMID:6813319 PMID:6975776 PMID:6992777 PMID:701277 PMID:7142115 PMID:7144800 PMID:7766032 Wikipedia:Tunicamycin Tunicamycin chebi_ontology CHEBI:29699 tunicamycin CHEBI:29699 CAS:11089-65-9 ChemIDplus CAS:11089-65-9 KEGG COMPOUND PMID:11478581 Europe PMC PMID:11514096 Europe PMC PMID:11732194 Europe PMC PMID:11798249 Europe PMC PMID:12093793 Europe PMC PMID:12106388 Europe PMC PMID:12136966 Europe PMC PMID:12232600 Europe PMC PMID:12232799 Europe PMC PMID:12515321 Europe PMC PMID:160437 Europe PMC PMID:1624425 Europe PMC PMID:3018444 Europe PMC PMID:315774 Europe PMC PMID:34700340 Europe PMC PMID:34979291 Europe PMC PMID:35233582 Europe PMC PMID:35370192 Europe PMC PMID:4624615 Europe PMC PMID:4630978 Europe PMC PMID:5103138 Europe PMC PMID:5103535 Europe PMC PMID:5168706 Europe PMC PMID:6153524 Europe PMC PMID:6813319 Europe PMC PMID:6975776 Europe PMC PMID:6992777 Europe PMC PMID:701277 Europe PMC PMID:7142115 Europe PMC PMID:7144800 Europe PMC PMID:7766032 Europe PMC Tunicamycin KEGG_COMPOUND A 16-membererd macrolide that is the aglycone of the antibiotic 5-O-beta-D-mycaminosyltylactone. 0 C23H38O5 InChI=1S/C23H38O5/c1-7-18-12-15(4)19(24)10-9-14(3)11-16(5)21(8-2)28-22(26)13-20(25)17(6)23(18)27/h9-11,15-18,20-21,23,25,27H,7-8,12-13H2,1-6H3/b10-9+,14-11+/t15-,16+,17+,18+,20-,21-,23-/m1/s1 YJSXTLYNFBFHAT-HJOMEYPASA-N 394.54480 394.27192 CC[C@H]1C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]1O CHEBI:76805 CAS:74758-60-4 KEGG:C12000 MetaCyc:CPD-15948 PMID:3733529 PMID:6511663 PMID:6735923 PMID:6833128 PMID:7118724 Reaxys:5765520 (4R,5S,6S,7S,9R,11E,13E,15S,16R)-7,16-diethyl-4,6-dihydroxy-5,9,13,15-tetramethyloxacyclohexadeca-11,13-diene-2,10-dione Tylactone tylactone chebi_ontology 20-Deoxo-12,13-desepoxy-12,13-dehydrorosaranolide 20-Dsdr 20-deoxo-23-deoxytylonolide Protylonolide CHEBI:29700 tylactone CHEBI:29700 CAS:74758-60-4 ChemIDplus CAS:74758-60-4 KEGG COMPOUND MetaCyc:CPD-15948 SUBMITTER PMID:3733529 Europe PMC PMID:6511663 Europe PMC PMID:6735923 Europe PMC PMID:6833128 Europe PMC PMID:7118724 Europe PMC Reaxys:5765520 Reaxys (4R,5S,6S,7S,9R,11E,13E,15S,16R)-7,16-diethyl-4,6-dihydroxy-5,9,13,15-tetramethyloxacyclohexadeca-11,13-diene-2,10-dione IUPAC Tylactone KEGG_COMPOUND tylactone UniProt 20-Deoxo-12,13-desepoxy-12,13-dehydrorosaranolide ChemIDplus 20-Dsdr ChemIDplus 20-deoxo-23-deoxytylonolide ChemIDplus Protylonolide KEGG_COMPOUND 0 NO2 46.00550 45.99290 *[N+](=O)[O-] nitro chebi_ontology -NO2 CHEBI:29785 nitro group CHEBI:29785 nitro IUPAC -NO2 IUPAC 0 HS 33.074 32.97990 *S[H] CHEBI:26821 CHEBI:29916 sulfanyl thiol thiol group chebi_ontology -SH HS- Mercaptogruppe Merkaptogruppe Sulfhydrylgruppe Thiolgruppe mercapto group sulfhydryl group sulphydryl group CHEBI:29917 thiol group CHEBI:29917 sulfanyl IUPAC thiol IUPAC thiol group UniProt -SH IUPAC HS- IUPAC Mercaptogruppe ChEBI Merkaptogruppe ChEBI Sulfhydrylgruppe ChEBI Thiolgruppe ChEBI mercapto group ChEBI sulfhydryl group ChEBI sulphydryl group ChEBI -1 HS InChI=1S/H2S/h1H2/p-1 RWSOTUBLDIXVET-UHFFFAOYSA-M 33.07394 32.98044 [S-][H] CAS:15035-72-0 Gmelin:24766 hydrogen(sulfide)(1-) hydrosulfide sulfanide chebi_ontology HS anion HS(-) hydrogen sulfide CHEBI:29919 hydrosulfide CHEBI:29919 CAS:15035-72-0 ChemIDplus CAS:15035-72-0 NIST Chemistry WebBook Gmelin:24766 Gmelin hydrogen(sulfide)(1-) IUPAC hydrosulfide IUPAC sulfanide IUPAC HS anion NIST_Chemistry_WebBook HS(-) IUPAC hydrogen sulfide UniProt 0 HO3S 81.07214 80.96464 S(=O)(O)(*)=O PDBeChem:SFO SULFO GROUP hydroxydioxo-lambda(6)-sulfanyl hydroxysulfonyl sulfo chebi_ontology -S(O)2(OH) CHEBI:29922 sulfo group CHEBI:29922 SULFO GROUP PDBeChem hydroxydioxo-lambda(6)-sulfanyl IUPAC hydroxysulfonyl IUPAC sulfo IUPAC -S(O)2(OH) IUPAC A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. -1 C2H3O2 InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1 QTBSBXVTEAMEQO-UHFFFAOYSA-M 59.04402 59.01385 CC([O-])=O CHEBI:13704 CHEBI:22165 CHEBI:40480 Beilstein:1901470 CAS:71-50-1 DrugBank:DB03166 Gmelin:1379 KEGG:C00033 MetaCyc:ACET PDBeChem:ACT PMID:17190852 PMID:22211106 PMID:22371380 Reaxys:1901470 UM-BBD_compID:c0050 Wikipedia:Acetate acetate chebi_ontology ACETATE ION Azetat CH3-COO(-) Ethanoat MeCO2 anion acetic acid, ion(1-) ethanoate CHEBI:30089 acetate CHEBI:30089 Beilstein:1901470 Beilstein CAS:71-50-1 ChemIDplus CAS:71-50-1 NIST Chemistry WebBook Gmelin:1379 Gmelin PMID:17190852 Europe PMC PMID:22211106 Europe PMC PMID:22371380 Europe PMC Reaxys:1901470 Reaxys UM-BBD_compID:c0050 UM-BBD acetate IUPAC acetate UniProt ACETATE ION PDBeChem Azetat ChEBI CH3-COO(-) IUPAC Ethanoat ChEBI MeCO2 anion NIST_Chemistry_WebBook acetic acid, ion(1-) ChemIDplus ethanoate ChEBI 0 H2N2 InChI=1S/H2N2/c1-2/h1-2H RAABOESOVLLHRU-UHFFFAOYSA-N 30.02936 30.02180 N=N CAS:3618-05-1 KEGG:C05360 diazene chebi_ontology Diimide HN=NH CHEBI:30096 diazene CHEBI:30096 CAS:3618-05-1 ChemIDplus CAS:3618-05-1 NIST Chemistry WebBook diazene IUPAC Diimide NIST_Chemistry_WebBook HN=NH IUPAC -1 HN2 InChI=1S/HN2/c1-2/h1H/q-1 XSCXGOPPNHTWEF-UHFFFAOYSA-N 29.02142 29.01452 N=[N-] diazenide chebi_ontology N=NH(-) CHEBI:30103 diazenide CHEBI:30103 diazenide IUPAC N=NH(-) IUPAC 0 N2 28.01348 28.00615 N(=N/*)\* diazenediyl chebi_ontology -N=N- azo diazene-1,2-diyl CHEBI:30106 azo group CHEBI:30106 diazenediyl IUPAC -N=N- IUPAC azo IUPAC diazene-1,2-diyl IUPAC A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. 0 C14H18N4O3 InChI=1S/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20) RIOXQFHNBCKOKP-UHFFFAOYSA-N 290.31770 290.13789 CCCCNC(=O)n1c(NC(=O)OC)nc2ccccc12 Beilstein:825455 CAS:17804-35-2 HMDB:HMDB0031767 KEGG:C10896 PMID:15813220 PMID:16903866 PMID:19049291 PMID:24693254 PMID:24782104 PMID:25045800 PMID:25104429 PMID:25145128 PPDB:66 Pesticides:benomyl Reaxys:825455 Wikipedia:Benomyl Benomyl methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate chebi_ontology 1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat 1-(Butylcarbamoyl)-2-benzimidazolecarbamic acid, methyl ester 1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol Benlate Methyl 1-(butylamino)carbonyl-1H-benzimidazol-2-ylcarbamate Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate Methyl N-(1-butylcarbamoyl-2-benzimidazole)carbamate CHEBI:3015 benomyl CHEBI:3015 Beilstein:825455 Beilstein CAS:17804-35-2 ChemIDplus CAS:17804-35-2 KEGG COMPOUND CAS:17804-35-2 NIST Chemistry WebBook PMID:15813220 Europe PMC PMID:16903866 Europe PMC PMID:19049291 Europe PMC PMID:24693254 Europe PMC PMID:24782104 Europe PMC PMID:25045800 Europe PMC PMID:25104429 Europe PMC PMID:25145128 Europe PMC Pesticides:benomyl Alan Wood's Pesticides Reaxys:825455 Reaxys Benomyl KEGG_COMPOUND methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate IUPAC 1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat ChemIDplus 1-(Butylcarbamoyl)-2-benzimidazolecarbamic acid, methyl ester ChemIDplus 1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol ChemIDplus Benlate KEGG_COMPOUND Methyl 1-(butylamino)carbonyl-1H-benzimidazol-2-ylcarbamate HMDB Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate HMDB Methyl N-(1-butylcarbamoyl-2-benzimidazole)carbamate HMDB 0 CS 44.07670 43.97207 S=C(*)* carbonothioyl thiocarbonyl chebi_ontology >C=S CHEBI:30256 thiocarbonyl group CHEBI:30256 carbonothioyl IUPAC thiocarbonyl IUPAC >C=S IUPAC An alkane-alpha,omega-diamine in which the alkane is ethane. 0 C2H8N2 InChI=1S/C2H8N2/c3-1-2-4/h1-4H2 PIICEJLVQHRZGT-UHFFFAOYSA-N 60.09840 60.06875 NCCN Beilstein:605263 CAS:107-15-3 Gmelin:1098 HMDB:HMDB0031225 KEGG:D01114 MetaCyc:CPD-3682 PDBeChem:EDN PMID:21616561 PMID:3692019 PMID:7070713 Reaxys:605263 Wikipedia:Ethylenediamine ethane-1,2-diamine ethylenediamine chebi_ontology 1,2-ethanediamine en CHEBI:30347 ethylenediamine CHEBI:30347 Beilstein:605263 Beilstein CAS:107-15-3 ChemIDplus CAS:107-15-3 NIST Chemistry WebBook Gmelin:1098 Gmelin PMID:21616561 Europe PMC PMID:3692019 Europe PMC PMID:7070713 Europe PMC Reaxys:605263 Reaxys ethane-1,2-diamine IUPAC ethylenediamine IUPAC 1,2-ethanediamine IUPAC en IUPAC +2 0.00000 [*++] CHEBI:23856 CHEBI:4665 KEGG:C00572 chebi_ontology Divalent cation divalent inorganic cations monoatomic dications CHEBI:30412 monoatomic dication CHEBI:30412 Divalent cation KEGG_COMPOUND divalent inorganic cations ChEBI monoatomic dications ChEBI +1 H3S InChI=1S/H2S/h1H2/p+1 RWSOTUBLDIXVET-UHFFFAOYSA-O 35.08982 34.99500 [H][S+]([H])[H] CAS:18155-21-0 Gmelin:307 sulfanium sulfonium trihydridosulfur(1+) chebi_ontology H3S(+) H3S+ [SH3](+) sulphonium CHEBI:30488 sulfonium CHEBI:30488 CAS:18155-21-0 ChemIDplus CAS:18155-21-0 NIST Chemistry WebBook Gmelin:307 Gmelin sulfanium IUPAC sulfonium IUPAC trihydridosulfur(1+) IUPAC H3S(+) IUPAC H3S+ NIST_Chemistry_WebBook [SH3](+) ChEBI sulphonium ChEBI A compound comprising a benzene ring core carrying a carboxylic acid substituent. 0 C7H6O2 InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9) WPYMKLBDIGXBTP-UHFFFAOYSA-N 122.12130 122.03678 OC(=O)c1ccccc1 CHEBI:22722 CHEBI:3029 CHEBI:41051 Beilstein:636131 CAS:65-85-0 DrugBank:DB03793 Drug_Central:4664 Gmelin:2946 HMDB:HMDB0001870 KEGG:C00180 KEGG:C00539 KEGG:D00038 KNApSAcK:C00000207 LINCS:LSM-37118 MetaCyc:BENZOATE PDBeChem:BEZ PMID:16728954 PMID:17439666 PMID:18314336 PPDB:1475 Reaxys:636131 Wikipedia:Benzoic_Acid YMDB:YMDB02301 BENZOIC ACID Benzoic acid benzoic acid chebi_ontology Aromatic carboxylic acid Benzenecarboxylic acid Benzeneformic acid Benzenemethanoic acid Benzoesaeure Dracylic acid E210 Phenylcarboxylic acid Phenylformic acid acide benzoique CHEBI:30746 benzoic acid CHEBI:30746 Beilstein:636131 Beilstein CAS:65-85-0 ChemIDplus CAS:65-85-0 KEGG COMPOUND CAS:65-85-0 NIST Chemistry WebBook Drug_Central:4664 DrugCentral Gmelin:2946 Gmelin PMID:16728954 Europe PMC PMID:17439666 Europe PMC PMID:18314336 Europe PMC Reaxys:636131 Reaxys BENZOIC ACID PDBeChem Benzoic acid KEGG_COMPOUND benzoic acid IUPAC Aromatic carboxylic acid KEGG_COMPOUND Benzenecarboxylic acid KEGG_COMPOUND Benzeneformic acid HMDB Benzenemethanoic acid HMDB Benzoesaeure ChEBI Dracylic acid KEGG_COMPOUND E210 ChEBI Phenylcarboxylic acid HMDB Phenylformic acid KEGG_COMPOUND acide benzoique ChEBI The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. 0 CH2O2 InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3) BDAGIHXWWSANSR-UHFFFAOYSA-N 46.02538 46.00548 [H]C(O)=O CHEBI:24082 CHEBI:42460 CHEBI:5145 BPDB:1749 Beilstein:1209246 CAS:64-18-6 DrugBank:DB01942 Gmelin:1008 HMDB:HMDB0000142 KEGG:C00058 KNApSAcK:C00001182 LIPID_MAPS_instance:LMFA01010040 MetaCyc:FORMATE PDBeChem:FMT PMID:12591956 PMID:14637377 PMID:15811469 PMID:16120414 PMID:16185830 PMID:16222862 PMID:16230297 PMID:16445901 PMID:16465784 PMID:18034701 PMID:18397576 PMID:22080171 PMID:22280475 PMID:22304812 PMID:22385261 PMID:22447125 PMID:22483350 PMID:22499553 PMID:22540994 PMID:22606986 PMID:22622393 PMID:3946945 PMID:7361809 Patent:CN101481304 Reaxys:1209246 Wikipedia:Formic_acid FORMIC ACID Formic acid formic acid chebi_ontology Acide formique Ameisensaeure H-COOH HCO2H HCOOH Methanoic acid aminic acid bilorin formylic acid hydrogen carboxylic acid methoic acid CHEBI:30751 formic acid CHEBI:30751 Beilstein:1209246 Beilstein CAS:64-18-6 ChemIDplus CAS:64-18-6 KEGG COMPOUND CAS:64-18-6 NIST Chemistry WebBook Gmelin:1008 Gmelin LIPID_MAPS_instance:LMFA01010040 LIPID MAPS PMID:12591956 Europe PMC PMID:14637377 Europe PMC PMID:15811469 Europe PMC PMID:16120414 Europe PMC PMID:16185830 Europe PMC PMID:16222862 Europe PMC PMID:16230297 Europe PMC PMID:16445901 Europe PMC PMID:16465784 Europe PMC PMID:18034701 Europe PMC PMID:18397576 Europe PMC PMID:22080171 Europe PMC PMID:22280475 Europe PMC PMID:22304812 Europe PMC PMID:22385261 Europe PMC PMID:22447125 Europe PMC PMID:22483350 Europe PMC PMID:22499553 Europe PMC PMID:22540994 Europe PMC PMID:22606986 Europe PMC PMID:22622393 Europe PMC PMID:3946945 Europe PMC PMID:7361809 Europe PMC Reaxys:1209246 Reaxys FORMIC ACID PDBeChem Formic acid KEGG_COMPOUND formic acid IUPAC Acide formique ChemIDplus Ameisensaeure ChemIDplus H-COOH IUPAC HCO2H ChEBI HCOOH NIST_Chemistry_WebBook Methanoic acid KEGG_COMPOUND aminic acid ChemIDplus bilorin ChemIDplus formylic acid ChemIDplus hydrogen carboxylic acid ChemIDplus methoic acid ChEBI A monohydroxybenzoate that is the conjugate base of salicylic acid. -1 C7H5O3 InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)/p-1 YGSDEFSMJLZEOE-UHFFFAOYSA-M 137.11280 137.02442 Oc1ccccc1C([O-])=O CHEBI:15061 CHEBI:26595 Beilstein:3605209 CAS:63-36-5 Gmelin:3417 KEGG:C00805 PMID:16669002 PMID:16934829 Reaxys:3605209 UM-BBD_compID:c0043 2-hydroxybenzoate Salicylate salicylate chebi_ontology 2-hydroxybenzoic acid ion(1-) o-hydroxybenzoate sal CHEBI:30762 salicylate CHEBI:30762 Beilstein:3605209 Beilstein CAS:63-36-5 ChemIDplus Gmelin:3417 Gmelin PMID:16669002 Europe PMC PMID:16934829 Europe PMC Reaxys:3605209 Reaxys UM-BBD_compID:c0043 UM-BBD 2-hydroxybenzoate IUPAC Salicylate KEGG_COMPOUND salicylate UniProt 2-hydroxybenzoic acid ion(1-) ChemIDplus o-hydroxybenzoate ChemIDplus sal IUPAC A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids. 0 C8H6O4 InChI=1S/C8H6O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H,9,10)(H,11,12) QQVIHTHCMHWDBS-UHFFFAOYSA-N 166.13084 166.02661 OC(=O)c1cccc(c1)C(O)=O Beilstein:1909332 CAS:121-91-5 Gmelin:27618 MetaCyc:CPD0-1267 PMID:24101250 Reaxys:1909332 Wikipedia:Isophthalic_acid benzene-1,3-dicarboxylic acid chebi_ontology IPA m-benzenedicarboxylic acid meta-benzenedicarboxylic acid CHEBI:30802 isophthalic acid CHEBI:30802 Beilstein:1909332 Beilstein CAS:121-91-5 ChemIDplus CAS:121-91-5 NIST Chemistry WebBook Gmelin:27618 Gmelin PMID:24101250 Europe PMC Reaxys:1909332 Reaxys benzene-1,3-dicarboxylic acid IUPAC IPA NIST_Chemistry_WebBook m-benzenedicarboxylic acid NIST_Chemistry_WebBook meta-benzenedicarboxylic acid ChEBI -2 C8H4O4 InChI=1S/C8H6O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H,9,10)(H,11,12)/p-2 QQVIHTHCMHWDBS-UHFFFAOYSA-L 164.11496 164.01206 [O-]C(=O)c1cccc(c1)C([O-])=O Beilstein:3906186 Gmelin:328933 benzene-1,3-dicarboxylate chebi_ontology 1,3-benzenedicarboxylate isophthalate CHEBI:30803 isophthalate(2-) CHEBI:30803 Beilstein:3906186 Beilstein Gmelin:328933 Gmelin benzene-1,3-dicarboxylate IUPAC 1,3-benzenedicarboxylate ChEBI isophthalate IUPAC isophthalate UniProt A dicarboxylic acid monoanion that is the conjugate base of isophthalic acid. -1 C8H5O4 InChI=1S/C8H6O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H,9,10)(H,11,12)/p-1 QQVIHTHCMHWDBS-UHFFFAOYSA-M 165.12290 165.01933 OC(=O)c1cccc(c1)C([O-])=O Gmelin:1947083 MetaCyc:CPD0-1267 3-carboxybenzoate chebi_ontology hydrogen isophthalate CHEBI:30804 isophthalate(1-) CHEBI:30804 Gmelin:1947083 Gmelin 3-carboxybenzoate IUPAC hydrogen isophthalate IUPAC A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. 0 HOR 17.007 17.00274 O[*] CHEBI:13804 CHEBI:22288 CHEBI:2553 KEGG:C00069 Alcohol alcohols chebi_ontology an alcohol CHEBI:30879 alcohol CHEBI:30879 Alcohol KEGG_COMPOUND alcohols IUPAC an alcohol UniProt 0 C6H14O6 182.172 182.07904 CHEBI:15093 CHEBI:26724 CHEBI:26726 CHEBI:33795 CHEBI:33796 CHEBI:9201 Beilstein:1721909 Gmelin:83165 Wikipedia:Sorbitol glucitol chebi_ontology Sorbitol gulitol rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol CHEBI:30911 glucitol CHEBI:30911 Beilstein:1721909 Beilstein Gmelin:83165 Gmelin glucitol IUPAC Sorbitol KEGG_COMPOUND gulitol ChEBI rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol IUPAC -1 C8H11N2O3S InChI=1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/p-1/t3-,4+,6-/m1/s1 NGHVIOIJCVXTGV-ALEPSDHESA-M 215.25062 215.04959 [H][C@@]1(N)C(=O)N2[C@]1([H])SC(C)(C)[C@]2([H])C([O-])=O CHEBI:12207 CHEBI:20704 Gmelin:604420 KEGG:C02954 (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate chebi_ontology CHEBI:30938 6-aminopenicillanate CHEBI:30938 Gmelin:604420 Gmelin (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals. -1 C5H9O2 InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)/p-1 NQPDZGIKBAWPEJ-UHFFFAOYSA-M 101.12376 101.06080 CCCCC([O-])=O CHEBI:14751 CHEBI:25890 Beilstein:3903735 CAS:10023-74-2 Gmelin:325619 PMID:17314444 PMID:18783570 Reaxys:3903735 pentanoate chebi_ontology CH3-[CH2]3-COO(-) n-propylacetate pentanoate pentanoic acid, ion(1-) CHEBI:31011 valerate CHEBI:31011 Beilstein:3903735 Beilstein CAS:10023-74-2 ChemIDplus Gmelin:325619 Gmelin PMID:17314444 Europe PMC PMID:18783570 Europe PMC Reaxys:3903735 Reaxys pentanoate IUPAC CH3-[CH2]3-COO(-) IUPAC n-propylacetate ChEBI pentanoate UniProt pentanoic acid, ion(1-) ChemIDplus A straight-chain saturated fatty acid anion that is the conjugate base of tetracosanoic acid (lignoceric acid), formed by deprotonation of the carboxy group. -1 C24H47O2 InChI=1S/C24H48O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h2-23H2,1H3,(H,25,26)/p-1 QZZGJDVWLFXDLK-UHFFFAOYSA-M 367.62880 367.35815 CCCCCCCCCCCCCCCCCCCCCCCC([O-])=O Gmelin:373325 MetaCyc:TETRACOSANOATE tetracosanoate chebi_ontology CH3-[CH2]22-COO(-) Lignocerat Tetracosanoat lignocerate n-tetracosanoate tetracosanate tetracosoate tetraeicosanoate CHEBI:31014 tetracosanoate CHEBI:31014 Gmelin:373325 Gmelin tetracosanoate IUPAC tetracosanoate UniProt CH3-[CH2]22-COO(-) IUPAC Lignocerat ChEBI Tetracosanoat ChEBI lignocerate CBN n-tetracosanoate ChEBI tetracosanate ChEBI tetracosoate ChEBI tetraeicosanoate ChEBI A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections. 0 C22H18N2 310.39170 310.14700 CAS:60628-96-8 DrugBank:DB04794 HMDB:HMDB0015583 KEGG:D01775 PMID:21746947 PMID:23066185 PMID:23283047 PMID:23467055 PMID:23586591 PMID:24215461 PMID:24849495 Reaxys:618427 Wikipedia:Bifonazole rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole chebi_ontology (+-)-1-(p,alpha-Diphenylbenzyl)imidazole (+-)-bifonazole (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (RS)-bifonazole 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole 1-(alpha-(4-Biphenylyl)benzyl)imidazole Mycospor bifonazol bifonazole bifonazolum rac-bifonazole racemic bifonazole CHEBI:31286 bifonazole CHEBI:31286 CAS:60628-96-8 ChemIDplus CAS:60628-96-8 KEGG DRUG PMID:21746947 Europe PMC PMID:23066185 Europe PMC PMID:23283047 Europe PMC PMID:23467055 Europe PMC PMID:23586591 Europe PMC PMID:24215461 Europe PMC PMID:24849495 Europe PMC Reaxys:618427 Reaxys rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole IUPAC (+-)-1-(p,alpha-Diphenylbenzyl)imidazole ChemIDplus (+-)-bifonazole ChEBI (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole DrugBank (RS)-bifonazole ChEBI 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole DrugBank 1-(alpha-(4-Biphenylyl)benzyl)imidazole ChemIDplus Mycospor KEGG_DRUG bifonazol DrugBank bifonazole KEGG_DRUG bifonazole WHO_MedNet bifonazolum DrugBank rac-bifonazole ChEBI racemic bifonazole ChEBI Any organic amino compound that is a derivative of ethylenediamine. chebi_ontology ethylenediamine derivatives CHEBI:31577 ethylenediamine derivative CHEBI:31577 ethylenediamine derivatives ChEBI 0 C53H85NO20 InChI=1S/C53H85NO20/c1-29-18-16-14-12-10-8-6-7-9-11-13-15-17-19-37(72-52-49(65)46(54)48(64)33(5)71-52)25-42-45(51(66)67)41(61)28-53(68,74-42)27-40(60)38(58)21-20-34(55)22-35(56)23-36(57)24-43(62)69-31(3)30(2)50(29)73-44-26-39(59)47(63)32(4)70-44/h6-7,9,11-19,29-42,44-50,52,55-61,63-65,68H,8,10,20-28,54H2,1-5H3,(H,66,67)/b7-6+,11-9+,14-12+,15-13+,18-16+,19-17+/t29-,30-,31-,32-,33+,34+,35+,36+,37-,38+,39+,40+,41-,42-,44?,45+,46-,47-,48+,49-,50+,52-,53+/m0/s1 IKYMLQOHQLVORI-PLAPNZKPSA-N 1056.250 1055.56649 [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](OC3C[C@@H](O)[C@@H](O)[C@H](C)O3)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 CAS:62997-67-5 HMDB:HMDB0242303 KEGG:C12156 LIPID_MAPS_instance:LMPK06000005 PMID:15504830 PMID:27803316 PMID:3182406 PMID:468732 (1S,3R,4R,7R,9R,11R,15S,16S,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-17-[(2,6-dideoxy-L-ribo-hexopyranosyl)oxy]-1,3,4,7,9,11,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid nystatin A3 chebi_ontology CHEBI:31927 nystatin A3 CHEBI:31927 CAS:62997-67-5 ChemIDplus LIPID_MAPS_instance:LMPK06000005 LIPID MAPS PMID:15504830 Europe PMC PMID:27803316 Europe PMC PMID:3182406 Europe PMC PMID:468732 Europe PMC (1S,3R,4R,7R,9R,11R,15S,16S,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-17-[(2,6-dideoxy-L-ribo-hexopyranosyl)oxy]-1,3,4,7,9,11,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid IUPAC nystatin A3 KEGG_COMPOUND 0 C9H12N2S InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) VRDIULHPQTYCLN-UHFFFAOYSA-N 180.271 180.07212 CCCC1=NC=CC(=C1)C(=S)N CHEBI:93717 CAS:14222-60-7 Drug_Central:2314 KEGG:D01195 LINCS:LSM-4210 Prothionamide prothionamide chebi_ontology 2-Propylisonicotinylthioamide 2-Propylthioisonicotinamide protionamid CHEBI:32066 Prothionamide CHEBI:32066 CAS:14222-60-7 DrugCentral CAS:14222-60-7 KEGG COMPOUND Drug_Central:2314 DrugCentral Prothionamide KEGG_COMPOUND prothionamide DrugCentral 2-Propylisonicotinylthioamide DrugCentral 2-Propylthioisonicotinamide DrugCentral protionamid DrugCentral 0 2C21H39N7O12.3H2O4S C42H84N14O36S3 InChI=1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1 QTENRWWVYAAPBI-YCRXJPFRSA-N 1457.389 1456.43348 OS(=O)(O)=O.[C@@H]1([C@H](O[C@@H]2[C@H]([C@@H]([C@@H](NC(=N)N)[C@@H]([C@H]2O)O)O)NC(N)=N)O[C@H]([C@@]1(C=O)O)C)O[C@H]3[C@H]([C@@H]([C@@H](O)[C@@H](O3)CO)O)NC.OS(=O)(O)=O.OS(=O)(O)=O.[C@@H]1([C@H](O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)NC(=N)N)O)NC(N)=N)O[C@H]([C@@]1(C=O)O)C)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC BPDB:2472 CAS:3810-74-0 KEGG:D01350 Streptomycin sulfate chebi_ontology CHEBI:32158 streptomycin sulfate CHEBI:32158 CAS:3810-74-0 KEGG COMPOUND Streptomycin sulfate KEGG_COMPOUND A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. 0 C12H14N4O4S InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) ZZORFUFYDOWNEF-UHFFFAOYSA-N 310.33012 310.07358 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 Beilstein:306856 CAS:122-11-2 DrugBank:DB06150 Drug_Central:2501 Gmelin:677830 HMDB:HMDB0015621 KEGG:D01142 LINCS:LSM-5790 PMID:11431418 PMID:12038137 PMID:13831481 PMID:13840927 PMID:14435331 PMID:14437387 PMID:16001847 PMID:16390193 PMID:18574183 PMID:19927815 Reaxys:306856 VSDB:1833 Wikipedia:Sulfadimethoxine 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide Sulfadimethoxine chebi_ontology 2,4-dimethoxy-6-sulfanilamido-1,3-diazine 2,6-dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidine 2,6-dimethoxy-4-sulfanilamidopyrimidine 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide 6-sulfanilamido-2,4-dimethoxypyrimidine Abcid (TN) Agribon (TN) N(1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide Sulfadimethoxydiazine Sulphadimethoxine sulfadimethoxinum sulfadimetoxina CHEBI:32161 sulfadimethoxine CHEBI:32161 Beilstein:306856 Beilstein CAS:122-11-2 ChemIDplus CAS:122-11-2 KEGG DRUG Drug_Central:2501 DrugCentral Gmelin:677830 Gmelin PMID:11431418 Europe PMC PMID:12038137 Europe PMC PMID:13831481 Europe PMC PMID:13840927 Europe PMC PMID:14435331 Europe PMC PMID:14437387 Europe PMC PMID:16001847 Europe PMC PMID:16390193 Europe PMC PMID:18574183 Europe PMC PMID:19927815 Europe PMC Reaxys:306856 Reaxys 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide IUPAC Sulfadimethoxine KEGG_DRUG 2,4-dimethoxy-6-sulfanilamido-1,3-diazine ChemIDplus 2,6-dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidine ChemIDplus 2,6-dimethoxy-4-sulfanilamidopyrimidine ChemIDplus 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide ChemIDplus 6-sulfanilamido-2,4-dimethoxypyrimidine ChemIDplus Abcid (TN) KEGG_DRUG Agribon (TN) KEGG_DRUG N(1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide ChemIDplus Sulfadimethoxydiazine ChemIDplus Sulphadimethoxine ChemIDplus sulfadimethoxinum ChemIDplus sulfadimetoxina ChemIDplus A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3. -1 C6H4NO2 InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)/p-1 PVNIIMVLHYAWGP-UHFFFAOYSA-M 122.10150 122.02475 [O-]C(=O)c1cccnc1 CHEBI:14650 CHEBI:22851 CHEBI:25530 Beilstein:3539722 Gmelin:327384 KEGG:C00253 MetaCyc:NIACINE PMID:17190852 PMID:21742010 PMID:21953179 Reaxys:3539722 nicotinate pyridine-3-carboxylate chebi_ontology 3-pyridinecarboxylate CHEBI:32544 nicotinate CHEBI:32544 Beilstein:3539722 Beilstein Gmelin:327384 Gmelin PMID:17190852 Europe PMC PMID:21742010 Europe PMC PMID:21953179 Europe PMC Reaxys:3539722 Reaxys nicotinate UniProt pyridine-3-carboxylate IUPAC 3-pyridinecarboxylate ChEBI A metal chloride salt with a K(+) counterion. 0 ClK InChI=1S/ClH.K/h1H;/q;+1/p-1 WCUXLLCKKVVCTQ-UHFFFAOYSA-M 74.55100 73.93256 [Cl-].[K+] CAS:7447-40-7 DrugBank:DB00761 KEGG:D02060 MetaCyc:KCL MolBase:881 Reaxys:3534978 Wikipedia:Potassium_Chloride potassium chloride chebi_ontology KCl Kaliumchlorid Kaon-Cl 10 Klor-con Klotrix Monopotassium chloride [KCl] muriate of potash sylvite CHEBI:32588 potassium chloride CHEBI:32588 CAS:7447-40-7 ChemIDplus CAS:7447-40-7 NIST Chemistry WebBook Reaxys:3534978 Reaxys potassium chloride IUPAC KCl IUPAC Kaliumchlorid ChEBI Kaon-Cl 10 KEGG_DRUG Klor-con KEGG_DRUG Klotrix KEGG_DRUG Monopotassium chloride DrugBank [KCl] MolBase muriate of potash NIST_Chemistry_WebBook sylvite ChEBI An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement. 0 C18H12 InChI=1S/C18H12/c1-2-6-14-10-18-12-16-8-4-3-7-15(16)11-17(18)9-13(14)5-1/h1-12H IFLREYGFSNHWGE-UHFFFAOYSA-N 228.28788 228.09390 c1ccc2cc3cc4ccccc4cc3cc2c1 Beilstein:1909299 CAS:92-24-0 Gmelin:306993 PMID:11493061 PMID:24655187 Reaxys:1909299 Wikipedia:Tetracene tetracene chebi_ontology 2,3-benzanthracene benz[b]anthracene naphthacene CHEBI:32600 tetracene CHEBI:32600 Beilstein:1909299 Beilstein CAS:92-24-0 ChemIDplus CAS:92-24-0 NIST Chemistry WebBook Gmelin:306993 Gmelin PMID:11493061 Europe PMC PMID:24655187 Europe PMC Reaxys:1909299 Reaxys tetracene IUPAC 2,3-benzanthracene NIST_Chemistry_WebBook benz[b]anthracene NIST_Chemistry_WebBook naphthacene IUPAC An alpha-amino-acid anion that is the conjugate base of serine. -1 C3H6NO3 InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p-1 MTCFGRXMJLQNBG-UHFFFAOYSA-M 104.08468 104.03532 NC(CO)C([O-])=O Gmelin:324692 serinate chebi_ontology 2-amino-3-hydroxypropanoate serine anion CHEBI:32845 serinate CHEBI:32845 Gmelin:324692 Gmelin serinate IUPAC 2-amino-3-hydroxypropanoate IUPAC serine anion JCBN An alpha-amino-acid cation that is the conjugate acid of serine. +1 C3H8NO3 InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/p+1 MTCFGRXMJLQNBG-UHFFFAOYSA-O 106.10056 106.04987 [NH3+]C(CO)C(O)=O Gmelin:1925675 serinium chebi_ontology 1-carboxy-2-hydroxyethanaminium serine cation CHEBI:32846 serinium CHEBI:32846 Gmelin:1925675 Gmelin serinium IUPAC 1-carboxy-2-hydroxyethanaminium IUPAC serine cation JCBN An optically active form of prolinate having L-configuration. -1 C5H8NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1/t4-/m0/s1 ONIBWKKTOPOVIA-BYPYZUCNSA-M 114.12250 114.05605 [O-]C(=O)[C@@H]1CCCN1 Beilstein:4307988 Gmelin:82610 Reaxys:4307988 L-prolinate chebi_ontology (2S)-pyrrolidine-2-carboxylate L-proline anion CHEBI:32862 L-prolinate CHEBI:32862 Beilstein:4307988 Beilstein Gmelin:82610 Gmelin Reaxys:4307988 Reaxys L-prolinate IUPAC (2S)-pyrrolidine-2-carboxylate IUPAC L-proline anion JCBN A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups. 0 HNR2 15.01460 15.01090 [H]N([*])[*] CHEBI:26618 CHEBI:9078 KEGG:C02324 Secondary amine secondary amines chebi_ontology R2NH sekundaeres Amin CHEBI:32863 secondary amine CHEBI:32863 Secondary amine KEGG_COMPOUND secondary amines IUPAC R2NH IUPAC sekundaeres Amin ChEBI An optically active form of prolinium having L-configuration. +1 C5H10NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1/t4-/m0/s1 ONIBWKKTOPOVIA-BYPYZUCNSA-O 116.13840 116.07060 OC(=O)[C@@H]1CCC[NH2+]1 Gmelin:363493 L-prolinium chebi_ontology (2S)-2-carboxypyrrolidinium L-proline cation CHEBI:32864 L-prolinium CHEBI:32864 Gmelin:363493 Gmelin L-prolinium IUPAC (2S)-2-carboxypyrrolidinium IUPAC L-proline cation JCBN An optically active form of prolinate having D-configuration. -1 C5H8NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1/t4-/m1/s1 ONIBWKKTOPOVIA-SCSAIBSYSA-M 114.12250 114.05605 [O-]C(=O)[C@H]1CCCN1 Gmelin:533350 D-prolinate chebi_ontology (2R)-pyrrolidine-2-carboxylate D-proline anion CHEBI:32867 D-prolinate CHEBI:32867 Gmelin:533350 Gmelin D-prolinate IUPAC (2R)-pyrrolidine-2-carboxylate IUPAC D-proline anion JCBN An optically active form of prolinium having D-configuration. +1 C5H10NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1/t4-/m1/s1 ONIBWKKTOPOVIA-SCSAIBSYSA-O 116.13840 116.07060 OC(=O)[C@H]1CCC[NH2+]1 Gmelin:363492 D-prolinium chebi_ontology (2R)-2-carboxypyrrolidinium D-proline cation CHEBI:32868 D-prolinium CHEBI:32868 Gmelin:363492 Gmelin D-prolinium IUPAC (2R)-2-carboxypyrrolidinium IUPAC D-proline cation JCBN An alpha-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group. -1 C5H8NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p-1 ONIBWKKTOPOVIA-UHFFFAOYSA-M 114.12256 114.05605 [O-]C(=O)C1CCCN1 Beilstein:5387795 Gmelin:50151 Reaxys:5387795 prolinate chebi_ontology pro(-) proline anion pyrrolidine-2-carboxylate CHEBI:32871 prolinate CHEBI:32871 Beilstein:5387795 Beilstein Gmelin:50151 Gmelin Reaxys:5387795 Reaxys prolinate IUPAC pro(-) IUPAC proline anion JCBN pyrrolidine-2-carboxylate IUPAC An alpha-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group. +1 C5H10NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/p+1 ONIBWKKTOPOVIA-UHFFFAOYSA-O 116.13840 116.07060 OC(=O)C1CCC[NH2+]1 prolinium chebi_ontology 2-carboxypyrrolidinium H2pro(+) proline cation CHEBI:32872 prolinium CHEBI:32872 prolinium IUPAC 2-carboxypyrrolidinium IUPAC H2pro(+) IUPAC proline cation JCBN A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups. 0 NR3 14.00670 14.00307 [*]N([*])[*] CHEBI:26879 CHEBI:9458 KEGG:C02196 Tertiary amine tertiary amines chebi_ontology R3N tertiaeres Amin CHEBI:32876 tertiary amine CHEBI:32876 Tertiary amine KEGG_COMPOUND tertiary amines IUPAC R3N IUPAC tertiaeres Amin ChEBI A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group. 0 H2NR 16.02260 16.01872 N[*] CHEBI:26263 CHEBI:26265 CHEBI:8407 CHEBI:8409 KEGG:C00375 KEGG:C00893 KEGG:C02580 Primary amine primary amines chebi_ontology Primary monoamine R-NH2 RCH2NH2 primaeres Amin CHEBI:32877 primary amine CHEBI:32877 Primary amine KEGG_COMPOUND primary amines IUPAC Primary monoamine KEGG_COMPOUND R-NH2 IUPAC RCH2NH2 KEGG_COMPOUND primaeres Amin ChEBI A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. CHEBI:13814 CHEBI:22474 CHEBI:2641 KEGG:C00706 Amine amines chebi_ontology Amin Substituted amine CHEBI:32952 amine CHEBI:32952 Amine KEGG_COMPOUND amines IUPAC Amin ChEBI Substituted amine KEGG_COMPOUND Any cyclic ether in which the oxygen atom forms part of a 3-membered ring. 0 C2OR4 40.02080 39.99491 [*]C1([*])OC1([*])[*] CHEBI:13828 CHEBI:23930 CHEBI:4812 KEGG:C00722 PMID:10891060 Wikipedia:Epoxide Epoxide epoxides chebi_ontology Alkene oxide Olefin oxide an epoxide epoxides CHEBI:32955 epoxide CHEBI:32955 PMID:10891060 Europe PMC Epoxide KEGG_COMPOUND epoxides IUPAC Alkene oxide KEGG_COMPOUND Olefin oxide KEGG_COMPOUND an epoxide UniProt epoxides ChEBI -1 C5H11N2O2 InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p-1 AHLPHDHHMVZTML-UHFFFAOYSA-M 131.15312 131.08260 NCCCC(N)C([O-])=O CHEBI:11448 CHEBI:19370 Gmelin:1242186 2,5-diaminopentanoate ornithinate chebi_ontology ornithine anion CHEBI:32964 ornithinate CHEBI:32964 Gmelin:1242186 Gmelin 2,5-diaminopentanoate IUPAC ornithinate IUPAC ornithine anion JCBN An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. CHEBI:22473 CHEBI:2633 KEGG:C00241 Amide amides chebi_ontology CHEBI:32988 amide CHEBI:32988 Amide KEGG_COMPOUND amides IUPAC -1 C7H5N2 InChI=1S/C7H5N2/c1-2-4-7-6(3-1)8-5-9-7/h1-5H/q-1 KLTWGRFNJPLFDA-UHFFFAOYSA-N 117.12808 117.04582 c1ccc2[n-]cnc2c1 Beilstein:3904522 Gmelin:326519 benzimidazol-1-ide chebi_ontology bim bzim CHEBI:33173 benzimidazolide CHEBI:33173 Beilstein:3904522 Beilstein Gmelin:326519 Gmelin benzimidazol-1-ide IUPAC bim IUPAC bzim IUPAC A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. CHEBI:10004 CHEBI:27305 Wikipedia:Vitamin chebi_ontology vitamin vitamina vitaminas vitamine vitamines vitamins vitaminum CHEBI:33229 vitamin (role) CHEBI:33229 vitamin ChEBI vitamina ChEBI vitaminas ChEBI vitamine ChEBI vitamines ChEBI vitamins ChEBI vitaminum ChEBI A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. chebi_ontology antitubercular antitubercular agents antitubercular drug antitubercular drugs tuberculostatic agent CHEBI:33231 antitubercular agent CHEBI:33231 antitubercular ChEBI antitubercular agents ChEBI antitubercular drug ChEBI antitubercular drugs ChEBI tuberculostatic agent ChEBI Intended use of the molecular entity or part thereof by humans. chebi_ontology CHEBI:33232 application CHEBI:33232 A particle not known to have substructure. elementary particle chebi_ontology elementary particles CHEBI:33233 fundamental particle CHEBI:33233 elementary particle IUPAC elementary particles ChEBI A monoatomic entity is a molecular entity consisting of a single atom. chebi_ontology atomic entity monoatomic entities CHEBI:33238 monoatomic entity CHEBI:33238 atomic entity ChEBI monoatomic entities ChEBI An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands). coordination entities coordination entity chebi_ontology coordination compounds CHEBI:33240 coordination entity CHEBI:33240 coordination entities IUPAC coordination entity IUPAC coordination compounds ChEBI chebi_ontology oxoacid derivatives CHEBI:33241 oxoacid derivative CHEBI:33241 oxoacid derivatives ChEBI chebi_ontology inorganic hydrides CHEBI:33242 inorganic hydride CHEBI:33242 inorganic hydrides ChEBI An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system. chebi_ontology organic fundamental parents organic parent hydrides CHEBI:33245 organic fundamental parent CHEBI:33245 organic fundamental parents ChEBI organic parent hydrides ChEBI Any substituent group which does not contain carbon. chebi_ontology inorganic groups CHEBI:33246 inorganic group CHEBI:33246 inorganic groups ChEBI Any substituent group or skeleton containing carbon. chebi_ontology organic groups CHEBI:33247 organic group CHEBI:33247 organic groups ChEBI A univalent group formed by removing a hydrogen atom from a hydrocarbon. hydrocarbyl group hydrocarbyl groups chebi_ontology groupe hydrocarbyle grupo hidrocarbilo grupos hidrocarbilo CHEBI:33248 hydrocarbyl group CHEBI:33248 hydrocarbyl group IUPAC hydrocarbyl groups IUPAC groupe hydrocarbyle IUPAC grupo hidrocarbilo IUPAC grupos hidrocarbilo IUPAC Any organic substituent group, regardless of functional type, having one free valence at a carbon atom. organyl group organyl groups chebi_ontology groupe organyle grupo organilo grupos organilo CHEBI:33249 organyl group CHEBI:33249 organyl group IUPAC organyl groups IUPAC groupe organyle IUPAC grupo organilo IUPAC grupos organilo IUPAC A chemical entity constituting the smallest component of an element having the chemical properties of the element. CHEBI:22671 CHEBI:23907 atom chebi_ontology atome atomo atoms atomus element elements CHEBI:33250 atom CHEBI:33250 atom IUPAC atome IUPAC atomo IUPAC atoms ChEBI atomus ChEBI element ChEBI elements ChEBI A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. nucleus chebi_ontology Atomkern Kern noyau noyau atomique nuclei nucleo nucleo atomico nucleus atomi CHEBI:33252 atomic nucleus CHEBI:33252 nucleus IUPAC Atomkern ChEBI Kern ChEBI noyau IUPAC noyau atomique ChEBI nuclei ChEBI nucleo IUPAC nucleo atomico ChEBI nucleus atomi ChEBI Heavy nuclear particle: proton or neutron. nucleon chebi_ontology Nukleon Nukleonen nucleons CHEBI:33253 nucleon CHEBI:33253 nucleon IUPAC nucleon IUPAC Nukleon ChEBI Nukleonen ChEBI nucleons ChEBI A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. primary amide primary amides chebi_ontology CHEBI:33256 primary amide CHEBI:33256 primary amide IUPAC primary amides IUPAC A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group. secondary amide secondary amides chebi_ontology CHEBI:33257 secondary amide CHEBI:33257 secondary amide IUPAC secondary amides IUPAC A molecular entity all atoms of which have the same atomic number. chebi_ontology homoatomic entity homoatomic molecular entities homoatomic molecular entity CHEBI:33259 elemental molecular entity CHEBI:33259 homoatomic entity ChEBI homoatomic molecular entities ChEBI homoatomic molecular entity ChEBI An organosulfur compound is a compound containing at least one carbon-sulfur bond. CHEBI:23010 CHEBI:25714 Wikipedia:Organosulfur_compounds organosulfur compound chebi_ontology organosulfur compounds CHEBI:33261 organosulfur compound CHEBI:33261 organosulfur compound ChEBI organosulfur compounds ChEBI 0 N2 28.013 28.00615 chebi_ontology CHEBI:33266 diatomic nitrogen CHEBI:33266 chebi_ontology CHEBI:33267 elemental nitrogen CHEBI:33267 An anion consisting of more than one atom. chebi_ontology polyatomic anions CHEBI:33273 polyatomic anion CHEBI:33273 polyatomic anions ChEBI chebi_ontology chemical messenger CHEBI:33280 molecular messenger CHEBI:33280 chemical messenger ChEBI A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. CHEBI:22582 PMID:12964249 PMID:22117953 PMID:22439833 PMID:22849268 PMID:22849276 PMID:22958833 chebi_ontology Antibiotika Antibiotikum antibiotic antibiotics antibiotique antimicrobial antimicrobial agents antimicrobials microbicide microbicides CHEBI:33281 antimicrobial agent CHEBI:33281 PMID:12964249 Europe PMC PMID:22117953 Europe PMC PMID:22439833 Europe PMC PMID:22849268 Europe PMC PMID:22849276 Europe PMC PMID:22958833 Europe PMC Antibiotika ChEBI Antibiotikum ChEBI antibiotic ChEBI antibiotics ChEBI antibiotique IUPAC antimicrobial ChEBI antimicrobial agents ChEBI antimicrobials ChEBI microbicide ChEBI microbicides ChEBI A substance (or active part thereof) that kills or slows the growth of bacteria. chebi_ontology antibacterial agents antibacterials bactericide bactericides CHEBI:33282 antibacterial agent CHEBI:33282 antibacterial agents ChEBI antibacterials ChEBI bactericide ChEBI bactericides ChEBI A nutrient is a food component that an organism uses to survive and grow. chebi_ontology nutrients CHEBI:33284 nutrient CHEBI:33284 nutrients ChEBI A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. chebi_ontology heteroorganic entities organoelement compounds CHEBI:33285 heteroorganic entity CHEBI:33285 heteroorganic entities ChEBI organoelement compounds ChEBI An agrochemical is a substance that is used in agriculture or horticulture. Wikipedia:Agrochemical chebi_ontology agrichemical agrichemicals agricultural chemicals agrochemicals CHEBI:33286 agrochemical CHEBI:33286 agrichemical ChEBI agrichemicals ChEBI agricultural chemicals ChEBI agrochemicals ChEBI A fertilizer is any substance that is added to soil or water to assist the growth of plants. chebi_ontology fertiliser fertilizers CHEBI:33287 fertilizer CHEBI:33287 fertiliser ChEBI fertilizers ChEBI An energy-rich substance that can be transformed with release of usable energy. chebi_ontology CHEBI:33292 fuel CHEBI:33292 A molecular entity containing one or more atoms of an alkali metal. chebi_ontology alkali metal molecular entities CHEBI:33296 alkali metal molecular entity CHEBI:33296 alkali metal molecular entities ChEBI Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth. pnictogens chebi_ontology group 15 elements group V elements nitrogenoideos nitrogenoides pnictogene pnictogenes CHEBI:33300 pnictogen CHEBI:33300 pnictogens IUPAC group 15 elements ChEBI group V elements ChEBI nitrogenoideos ChEBI nitrogenoides ChEBI pnictogene ChEBI pnictogenes ChEBI A p-block molecular entity containing any pnictogen. pnictogen molecular entity chebi_ontology pnictogen molecular entities CHEBI:33302 pnictogen molecular entity CHEBI:33302 pnictogen molecular entity ChEBI pnictogen molecular entities ChEBI Any p-block element belonging to the group 16 family of the periodic table. PMID:17084588 chalcogen chalcogens chebi_ontology Chalkogen Chalkogene anfigeno anfigenos calcogeno calcogenos chalcogene chalcogenes group 16 elements group VI elements CHEBI:33303 chalcogen CHEBI:33303 PMID:17084588 Europe PMC chalcogen IUPAC chalcogens IUPAC Chalkogen ChEBI Chalkogene ChEBI anfigeno ChEBI anfigenos ChEBI calcogeno ChEBI calcogenos ChEBI chalcogene ChEBI chalcogenes ChEBI group 16 elements ChEBI group VI elements ChEBI Any p-block molecular entity containing a chalcogen. chalcogen molecular entity chebi_ontology chalcogen compounds chalcogen molecular entities CHEBI:33304 chalcogen molecular entity CHEBI:33304 chalcogen molecular entity ChEBI chalcogen compounds ChEBI chalcogen molecular entities ChEBI group 14 elements chebi_ontology carbon group element carbon group elements carbonoides cristallogene cristallogenes group IV elements CHEBI:33306 carbon group element atom CHEBI:33306 group 14 elements IUPAC carbon group element ChEBI carbon group elements ChEBI carbonoides ChEBI cristallogene ChEBI cristallogenes ChEBI group IV elements ChEBI An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. 0 CO2R2 44.010 43.98983 [*]C(=O)O[*] CHEBI:13204 CHEBI:23028 CHEBI:3408 KEGG:C02391 Wikipedia:Ester Carboxylic ester carboxylic esters chebi_ontology a carboxylic ester carboxylic acid esters CHEBI:33308 carboxylic ester CHEBI:33308 Carboxylic ester KEGG_COMPOUND carboxylic esters IUPAC a carboxylic ester UniProt carboxylic acid esters ChEBI An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table. main group elements chebi_ontology Hauptgruppenelement Hauptgruppenelemente main group element CHEBI:33318 main group element atom CHEBI:33318 main group elements IUPAC Hauptgruppenelement ChEBI Hauptgruppenelemente ChEBI main group element ChEBI A group derived from an arene by removal of a hydrogen atom from a ring carbon atom. aryl groups chebi_ontology Arylgruppe groupe aryle grupos arilo CHEBI:33338 aryl group CHEBI:33338 aryl groups IUPAC Arylgruppe ChEBI groupe aryle IUPAC grupos arilo IUPAC group 12 elements chebi_ontology zinc group element zinc group elements CHEBI:33340 zinc group element atom CHEBI:33340 group 12 elements IUPAC zinc group element ChEBI zinc group elements ChEBI group 7 elements chebi_ontology manganese group element manganese group elements CHEBI:33352 manganese group element atom CHEBI:33352 group 7 elements IUPAC manganese group element ChEBI manganese group elements ChEBI group 11 elements chebi_ontology coinage metals copper group element copper group elements CHEBI:33366 copper group element atom CHEBI:33366 group 11 elements IUPAC coinage metals ChEBI copper group element ChEBI copper group elements ChEBI chebi_ontology oxoacids of sulfur sulfur oxoacids CHEBI:33402 sulfur oxoacid CHEBI:33402 oxoacids of sulfur ChEBI sulfur oxoacids ChEBI A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). hydracid chebi_ontology hydracids CHEBI:33405 hydracid CHEBI:33405 hydracid IUPAC hydracids ChEBI chebi_ontology pnictogen oxoacids CHEBI:33408 pnictogen oxoacid CHEBI:33408 pnictogen oxoacids ChEBI sulfur oxoacid derivative chebi_ontology sulfur oxoacid derivatives CHEBI:33424 sulfur oxoacid derivative CHEBI:33424 sulfur oxoacid derivative ChEBI sulfur oxoacid derivatives ChEBI -1 0.00000 [*-] chebi_ontology monoatomic monoanions CHEBI:33429 monoatomic monoanion CHEBI:33429 monoatomic monoanions ChEBI chebi_ontology CHEBI:33431 elemental chlorine CHEBI:33431 0 Cl 35.453 34.96885 chebi_ontology atomic chlorine CHEBI:33432 monoatomic chlorine CHEBI:33432 atomic chlorine ChEBI chebi_ontology monoatomic halogens CHEBI:33433 monoatomic halogen CHEBI:33433 monoatomic halogens ChEBI elemental halogen chebi_ontology elemental halogens CHEBI:33434 elemental halogen CHEBI:33434 elemental halogen ChEBI elemental halogens ChEBI Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid. CHEBI:15132 CHEBI:25406 CHEBI:26086 CHEBI:9320 KEGG:C00934 PMID:18186488 phospho sugar chebi_ontology monosaccharide phosphates phospho sugars phosphorylated sugar phosphorylated sugars phosphosugar phosphosugars CHEBI:33447 phospho sugar CHEBI:33447 PMID:18186488 Europe PMC phospho sugar ChEBI monosaccharide phosphates ChEBI phospho sugars ChEBI phosphorylated sugar ChEBI phosphorylated sugars ChEBI phosphosugar ChEBI phosphosugars ChEBI A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons. phosphorus oxoacid chebi_ontology Oxosaeure des Phosphors oxoacids of phosphorus phosphorus oxoacids CHEBI:33457 phosphorus oxoacid CHEBI:33457 phosphorus oxoacid ChEBI Oxosaeure des Phosphors ChEBI oxoacids of phosphorus ChEBI phosphorus oxoacids ChEBI pnictogen oxoanion chebi_ontology pnictogen oxoanions CHEBI:33459 pnictogen oxoanion CHEBI:33459 pnictogen oxoanion ChEBI pnictogen oxoanions ChEBI phosphorus oxoanion chebi_ontology oxoanions of phosphorus phosphorus oxoanions CHEBI:33461 phosphorus oxoanion CHEBI:33461 phosphorus oxoanion ChEBI oxoanions of phosphorus ChEBI phosphorus oxoanions ChEBI A monovalent inorganic anion obtained by deprotonation of one of the two OH groups in phosphonic acid. -1 H2O3P InChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)/p-1 ABLZXFCXXLZCGV-UHFFFAOYSA-M 80.987 80.97470 [H]P([O-])(O[H])=O PDBeChem:78T hydridohydroxidodioxidophosphate(1-) hydrogen phosphonate chebi_ontology [PHO2(OH)](-) hydrogenphosphonate CHEBI:33462 phosphonate(1-) CHEBI:33462 hydridohydroxidodioxidophosphate(1-) IUPAC hydrogen phosphonate IUPAC [PHO2(OH)](-) IUPAC hydrogenphosphonate IUPAC elemental pnictogen chebi_ontology elemental pnictogens CHEBI:33465 elemental pnictogen CHEBI:33465 elemental pnictogen ChEBI elemental pnictogens ChEBI sulfur oxoanion chebi_ontology oxoanions of sulfur sulfur oxoanions CHEBI:33482 sulfur oxoanion CHEBI:33482 sulfur oxoanion ChEBI oxoanions of sulfur ChEBI sulfur oxoanions ChEBI chalcogen oxoacid chebi_ontology chalcogen oxoacids CHEBI:33484 chalcogen oxoacid CHEBI:33484 chalcogen oxoacid ChEBI chalcogen oxoacids ChEBI chalcogen oxoanion chebi_ontology chalcogen oxoanions CHEBI:33485 chalcogen oxoanion CHEBI:33485 chalcogen oxoanion ChEBI chalcogen oxoanions ChEBI A molecular entity containing one or more atoms of a transition element. chebi_ontology transition element molecular entities transition metal molecular entity CHEBI:33497 transition element molecular entity CHEBI:33497 transition element molecular entities ChEBI transition metal molecular entity ChEBI chebi_ontology alkali metal cations CHEBI:33504 alkali metal cation CHEBI:33504 alkali metal cations ChEBI chebi_ontology transition element cations transition metal cation CHEBI:33515 transition element cation CHEBI:33515 transition element cations ChEBI transition metal cation ChEBI An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity. CHEBI:25217 CHEBI:6788 KEGG:C00050 PMID:21784043 Wikipedia:Metal chebi_ontology elemental metal elemental metals metal element metal elements metals CHEBI:33521 metal atom CHEBI:33521 PMID:21784043 Europe PMC elemental metal ChEBI elemental metals ChEBI metal element ChEBI metal elements ChEBI metals ChEBI sulfur hydride chebi_ontology hydrides of sulfur sulfur hydrides sulphur hydrides CHEBI:33535 sulfur hydride CHEBI:33535 sulfur hydride ChEBI hydrides of sulfur ChEBI sulfur hydrides ChEBI sulphur hydrides ChEBI The sulfur oxoanion formed by deprotonation of sulfonic acid. -1 HO3S InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1 BDHFUVZGWQCTTF-UHFFFAOYSA-M 81.07214 80.96519 [H]S([O-])(=O)=O Gmelin:971569 hydridotrioxidosulfate(1-) chebi_ontology SHO3(-) [SHO3](-) sulfonates CHEBI:33543 sulfonate CHEBI:33543 Gmelin:971569 Gmelin hydridotrioxidosulfate(1-) IUPAC SHO3(-) IUPAC [SHO3](-) IUPAC sulfonates ChEBI An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon. 0 HO3SR 81.07100 80.96464 OS([*])(=O)=O chebi_ontology organosulfonic acids sulfonic acids CHEBI:33551 organosulfonic acid CHEBI:33551 organosulfonic acids ChEBI sulfonic acids ChEBI sulfonic acid derivative chebi_ontology derivatives of sulfonic acid sulfonic acid derivatives CHEBI:33552 sulfonic acid derivative CHEBI:33552 sulfonic acid derivative ChEBI derivatives of sulfonic acid ChEBI sulfonic acid derivatives ChEBI An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid. -1 O3SR 80.064 79.95681 *S([O-])(=O)=O chebi_ontology organosulfonate organosulfonate oxoanions organosulfonates CHEBI:33554 organosulfonate oxoanion CHEBI:33554 organosulfonate ChEBI organosulfonate oxoanions ChEBI organosulfonates ChEBI Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group. chebi_ontology arenesulfonic acids arylsulfonic acid arylsulfonic acids CHEBI:33555 arenesulfonic acid CHEBI:33555 arenesulfonic acids ChEBI arylsulfonic acid ChEBI arylsulfonic acids ChEBI An amino-acid anion obtained by deprotonation of any alpha-amino acid. alpha-amino-acid anion chebi_ontology alpha-amino acid anions alpha-amino-acid anions CHEBI:33558 alpha-amino-acid anion CHEBI:33558 alpha-amino-acid anion ChEBI alpha-amino acid anions ChEBI alpha-amino-acid anions ChEBI chebi_ontology s-block element s-block elements CHEBI:33559 s-block element atom CHEBI:33559 s-block element ChEBI s-block elements ChEBI Any main group element atom belonging to the p-block of the periodic table. chebi_ontology p-block element p-block elements CHEBI:33560 p-block element atom CHEBI:33560 p-block element ChEBI p-block elements ChEBI chebi_ontology d-block element d-block elements CHEBI:33561 d-block element atom CHEBI:33561 d-block element ChEBI d-block elements ChEBI CHEBI:22705 CHEBI:22711 chebi_ontology CHEBI:33570 benzenediols CHEBI:33570 Any benzenediol in which the two hydroxy groups are meta to one another. chebi_ontology CHEBI:33572 resorcinols CHEBI:33572 A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. 0 CHO2R 45.017 45.01740 44.99765 OC([*])=O CHEBI:13428 CHEBI:13627 CHEBI:23027 PMID:17147560 PMID:18433345 Wikipedia:Carboxylic_acid carboxylic acid carboxylic acids chebi_ontology Carbonsaeure Carbonsaeuren Karbonsaeure RC(=O)OH acide carboxylique acides carboxyliques acido carboxilico acidos carboxilicos CHEBI:33575 carboxylic acid CHEBI:33575 PMID:17147560 Europe PMC PMID:18433345 Europe PMC carboxylic acid IUPAC carboxylic acids IUPAC Carbonsaeure ChEBI Carbonsaeuren ChEBI Karbonsaeure ChEBI RC(=O)OH IUPAC acide carboxylique IUPAC acides carboxyliques IUPAC acido carboxilico IUPAC acidos carboxilicos IUPAC A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. chebi_ontology main group compounds main group molecular entities CHEBI:33579 main group molecular entity CHEBI:33579 main group compounds ChEBI main group molecular entities ChEBI carbon group molecular entity chebi_ontology carbon group molecular entities CHEBI:33582 carbon group molecular entity CHEBI:33582 carbon group molecular entity ChEBI carbon group molecular entities ChEBI Any molecule that consists of a series of atoms joined together to form a ring. Wikipedia:Cyclic_compound chebi_ontology cyclic compounds CHEBI:33595 cyclic compound CHEBI:33595 cyclic compounds ChEBI A cyclic compound having as ring members atoms of the same element only. homocyclic compound homocyclic compounds chebi_ontology isocyclic compounds CHEBI:33597 homocyclic compound CHEBI:33597 homocyclic compound IUPAC homocyclic compounds IUPAC isocyclic compounds IUPAC A homocyclic compound in which all of the ring members are carbon atoms. carbocyclic compound carbocyclic compounds chebi_ontology carbocycle CHEBI:33598 carbocyclic compound CHEBI:33598 carbocyclic compound IUPAC carbocyclic compounds IUPAC carbocycle ChEBI A compound having one atom as the only common member of two rings. spiro compound spiro compounds chebi_ontology spiro-fused compounds spirocycle spirocycles spirocyclic compound spirocyclic compounds spirofused compounds CHEBI:33599 spiro compound CHEBI:33599 spiro compound IUPAC spiro compounds IUPAC spiro-fused compounds IUPAC spirocycle ChEBI spirocycles ChEBI spirocyclic compound ChEBI spirocyclic compounds ChEBI spirofused compounds ChEBI chebi_ontology hydrogen compounds hydrogen molecular entities CHEBI:33608 hydrogen molecular entity CHEBI:33608 hydrogen compounds ChEBI hydrogen molecular entities ChEBI chebi_ontology polycyclic compounds CHEBI:33635 polycyclic compound CHEBI:33635 polycyclic compounds ChEBI A molecule that features two fused rings. chebi_ontology bicyclic compounds CHEBI:33636 bicyclic compound CHEBI:33636 bicyclic compounds ChEBI A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms. ortho-fused polycyclic compounds chebi_ontology ortho-fused compounds CHEBI:33637 ortho-fused compound CHEBI:33637 ortho-fused polycyclic compounds IUPAC ortho-fused compounds ChEBI Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes. olefin olefins chebi_ontology olefins CHEBI:33641 olefin CHEBI:33641 olefin IUPAC olefins IUPAC olefins ChEBI Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds. aliphatic compounds chebi_ontology CHEBI:33653 aliphatic compound CHEBI:33653 aliphatic compounds IUPAC A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. aromatic compounds aromatic molecular entity chebi_ontology aromatics aromatische Verbindungen CHEBI:33655 aromatic compound CHEBI:33655 aromatic compounds IUPAC aromatic molecular entity IUPAC aromatics ChEBI aromatische Verbindungen ChEBI Any monocyclic or polycyclic aromatic hydrocarbon. arene arenes chebi_ontology aromatic hydrocarbons CHEBI:33658 arene CHEBI:33658 arene IUPAC arenes IUPAC aromatic hydrocarbons IUPAC chebi_ontology organic aromatic compounds CHEBI:33659 organic aromatic compound CHEBI:33659 organic aromatic compounds ChEBI chebi_ontology monocyclic compounds CHEBI:33661 monocyclic compound CHEBI:33661 monocyclic compounds ChEBI A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms. annulene annulenes chebi_ontology CHEBI:33662 annulene CHEBI:33662 annulene IUPAC annulenes IUPAC cyclic hydrocarbon chebi_ontology cyclic hydrocarbons CHEBI:33663 cyclic hydrocarbon CHEBI:33663 cyclic hydrocarbon ChEBI cyclic hydrocarbons ChEBI monocyclic hydrocarbon monocyclic hydrocarbons chebi_ontology monocyclic hydrocarbons CHEBI:33664 monocyclic hydrocarbon CHEBI:33664 monocyclic hydrocarbon ChEBI monocyclic hydrocarbons IUPAC monocyclic hydrocarbons ChEBI polycyclic hydrocarbon polycyclic hydrocarbons chebi_ontology CHEBI:33666 polycyclic hydrocarbon CHEBI:33666 polycyclic hydrocarbon IUPAC polycyclic hydrocarbons IUPAC heteromonocyclic compound heteromonocyclic compounds chebi_ontology CHEBI:33670 heteromonocyclic compound CHEBI:33670 heteromonocyclic compound IUPAC heteromonocyclic compounds IUPAC A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. heteropolycyclic compounds chebi_ontology polyheterocyclic compounds CHEBI:33671 heteropolycyclic compound CHEBI:33671 heteropolycyclic compounds IUPAC polyheterocyclic compounds ChEBI A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. heterobicyclic compounds chebi_ontology CHEBI:33672 heterobicyclic compound CHEBI:33672 heterobicyclic compounds IUPAC chebi_ontology zinc group molecular entities CHEBI:33673 zinc group molecular entity CHEBI:33673 zinc group molecular entities ChEBI An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. s-block molecular entity chebi_ontology s-block compounds s-block molecular entities CHEBI:33674 s-block molecular entity CHEBI:33674 s-block molecular entity ChEBI s-block compounds ChEBI s-block molecular entities ChEBI A main group molecular entity that contains one or more atoms of a p-block element. chebi_ontology p-block compounds p-block molecular entities p-block molecular entitiy CHEBI:33675 p-block molecular entity CHEBI:33675 p-block compounds ChEBI p-block molecular entities ChEBI p-block molecular entitiy ChEBI A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element. d-block molecular entity chebi_ontology d-block compounds d-block molecular entities CHEBI:33676 d-block molecular entity CHEBI:33676 d-block molecular entity ChEBI d-block compounds ChEBI d-block molecular entities ChEBI Hydrides are chemical compounds of hydrogen with other chemical elements. chebi_ontology CHEBI:33692 hydrides CHEBI:33692 oxygen hydride chebi_ontology hydrides of oxygen oxygen hydrides CHEBI:33693 oxygen hydride CHEBI:33693 oxygen hydride ChEBI hydrides of oxygen ChEBI oxygen hydrides ChEBI A macromolecule formed by a living organism. biopolymer chebi_ontology Biopolymere biomacromolecules biopolymers CHEBI:33694 biomacromolecule CHEBI:33694 biopolymer IUPAC Biopolymere ChEBI biomacromolecules ChEBI biopolymers ChEBI chebi_ontology genetically encoded biomacromolecules genetically encoded biopolymers information biomacromolecules information biopolymers information macromolecule information macromolecules CHEBI:33695 information biomacromolecule CHEBI:33695 genetically encoded biomacromolecules ChEBI genetically encoded biopolymers ChEBI information biomacromolecules ChEBI information biopolymers ChEBI information macromolecule ChEBI information macromolecules ChEBI A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid. nucleic acids chebi_ontology NA Nukleinsaeure Nukleinsaeuren acide nucleique acides nucleiques acido nucleico acidos nucleicos CHEBI:33696 nucleic acid CHEBI:33696 nucleic acids IUPAC NA ChEBI Nukleinsaeure ChEBI Nukleinsaeuren ChEBI acide nucleique ChEBI acides nucleiques ChEBI acido nucleico ChEBI acidos nucleicos ChEBI High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. CAS:63231-63-0 ribonucleic acid ribonucleic acids chebi_ontology RNA RNS Ribonukleinsaeure pentosenucleic acids ribonucleic acids ribose nucleic acid yeast nucleic acid CHEBI:33697 ribonucleic acid CHEBI:33697 CAS:63231-63-0 ChemIDplus ribonucleic acid IUPAC ribonucleic acids IUPAC RNA IUPAC RNA UniProt RNS ChEBI Ribonukleinsaeure ChEBI pentosenucleic acids ChemIDplus ribonucleic acids ChEBI ribose nucleic acid ChEBI yeast nucleic acid ChEBI chebi_ontology canonical amino-acid residue canonical amino-acid residues common amino acid residues proteinogenic amino-acid residues standard amino acid residues standard amino-acid residues CHEBI:33700 proteinogenic amino-acid residue CHEBI:33700 canonical amino-acid residue ChEBI canonical amino-acid residues ChEBI common amino acid residues ChEBI proteinogenic amino-acid residues ChEBI standard amino acid residues ChEBI standard amino-acid residues ChEBI A cation consisting of more than one atom. chebi_ontology polyatomic cations CHEBI:33702 polyatomic cation CHEBI:33702 polyatomic cations ChEBI amino-acid cation chebi_ontology amino acid cation amino-acid cations CHEBI:33703 amino-acid cation CHEBI:33703 amino-acid cation ChEBI amino acid cation ChEBI amino-acid cations ChEBI An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group. 0 C2H4NO2R 74.05870 74.02420 NC([*])C(O)=O CHEBI:10208 CHEBI:13779 CHEBI:22442 CHEBI:2642 KEGG:C00045 KEGG:C05167 alpha-amino acid chebi_ontology Amino acid Amino acids alpha-amino acids alpha-amino carboxylic acids CHEBI:33704 alpha-amino acid CHEBI:33704 alpha-amino acid IUPAC Amino acid KEGG_COMPOUND Amino acids KEGG_COMPOUND alpha-amino acids ChEBI alpha-amino acids JCBN alpha-amino carboxylic acids IUPAC When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. amino-acid residue chebi_ontology amino acid residue amino-acid residues CHEBI:33708 amino-acid residue CHEBI:33708 amino-acid residue IUPAC amino acid residue ChEBI amino-acid residues JCBN A carboxylic acid containing one or more amino groups. CHEBI:13815 CHEBI:22477 Wikipedia:Amino_acid chebi_ontology Aminocarbonsaeure Aminokarbonsaeure Aminosaeure amino acids CHEBI:33709 amino acid CHEBI:33709 Aminocarbonsaeure ChEBI Aminokarbonsaeure ChEBI Aminosaeure ChEBI amino acids ChEBI 0 C25H43N14O7R 522.519 522.24113 NC1NC(CC=N1)[C@@H]1NC(=O)\C(NC(=O)[C@@H](CN[*])NC(=O)[C@@H](C[*])NC(=O)[C@@H](N)CNC1=O)=C\NC(N)=O CAS:11003-38-6 KEGG:C01790 KEGG:D07607 Capreomycin chebi_ontology capreomycins CHEBI:3371 capreomycin CHEBI:3371 CAS:11003-38-6 KEGG COMPOUND Capreomycin KEGG_COMPOUND capreomycins ChEBI An amino-acid residue derived from an alpha-amino acid. 0 C2H2NOR 56.043 56.01364 *-NC([*])C(-*)=O chebi_ontology alpha-amino-acid residues an alpha-amino acid residue CHEBI:33710 alpha-amino-acid residue CHEBI:33710 alpha-amino-acid residues ChEBI an alpha-amino acid residue UniProt alpha-amino-acid cation chebi_ontology alpha-amino acid cations alpha-amino-acid cations CHEBI:33719 alpha-amino-acid cation CHEBI:33719 alpha-amino-acid cation ChEBI alpha-amino acid cations ChEBI alpha-amino-acid cations ChEBI manganese group molecular entity chebi_ontology manganese group molecular entities CHEBI:33743 manganese group molecular entity CHEBI:33743 manganese group molecular entity ChEBI manganese group molecular entities ChEBI copper group molecular entity chebi_ontology copper group molecular entities CHEBI:33745 copper group molecular entity CHEBI:33745 copper group molecular entity ChEBI copper group molecular entities ChEBI chebi_ontology canonical nucleoside residues common nucleoside residues nucleoside residue standard nucleoside residues CHEBI:33791 canonical nucleoside residue CHEBI:33791 canonical nucleoside residues ChEBI common nucleoside residues CBN nucleoside residue CBN standard nucleoside residues ChEBI chebi_ontology N Nuc canonical ribonucleoside residues common ribonucleoside residue common ribonucleoside residues standard ribonucleoside residues CHEBI:33792 canonical ribonucleoside residue CHEBI:33792 N CBN Nuc CBN canonical ribonucleoside residues ChEBI common ribonucleoside residue CBN common ribonucleoside residues CBN standard ribonucleoside residues ChEBI An organic compound having at least one hydroxy group attached to a carbon atom. CHEBI:64710 hydroxy compounds chebi_ontology organic alcohol organic hydroxy compounds CHEBI:33822 organic hydroxy compound CHEBI:33822 hydroxy compounds IUPAC organic alcohol ChEBI organic hydroxy compounds ChEBI Any organic molecule that consists of atoms connected in the form of a ring. chebi_ontology organic cyclic compounds CHEBI:33832 organic cyclic compound CHEBI:33832 organic cyclic compounds ChEBI A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). heteroarenes chebi_ontology hetarenes CHEBI:33833 heteroarene CHEBI:33833 heteroarenes IUPAC hetarenes IUPAC chebi_ontology benzenoid aromatic compounds benzenoid compound CHEBI:33836 benzenoid aromatic compound CHEBI:33836 benzenoid aromatic compounds ChEBI benzenoid compound ChEBI An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents. 0 C5H8O3R2 116.115 116.04734 [C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO CHEBI:13661 CHEBI:25611 CHEBI:7647 KEGG:C00801 Wikipedia:Nucleoside Nucleoside nucleosides chebi_ontology a nucleoside nucleosides CHEBI:33838 nucleoside CHEBI:33838 Nucleoside KEGG_COMPOUND nucleosides IUPAC a nucleoside UniProt nucleosides ChEBI A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Wikipedia:Macromolecule macromolecule chebi_ontology macromolecules polymer polymer molecule polymers CHEBI:33839 macromolecule CHEBI:33839 macromolecule IUPAC macromolecules ChEBI polymer ChEBI polymer molecule IUPAC polymers ChEBI chebi_ontology aromatic annulenes CHEBI:33842 aromatic annulene CHEBI:33842 aromatic annulenes ChEBI A monocyclic aromatic hydrocarbon. chebi_ontology monocyclic arenes CHEBI:33847 monocyclic arene CHEBI:33847 monocyclic arenes ChEBI A polycyclic aromatic hydrocarbon. PMID:15198916 PMID:25679824 Wikipedia:Polycyclic_aromatic_hydrocarbon chebi_ontology PAH PAHs polycyclic arenes polycyclic aromatic hydrocarbons CHEBI:33848 polycyclic arene CHEBI:33848 PMID:15198916 Europe PMC PMID:25679824 Europe PMC PAH ChEBI PAHs ChEBI polycyclic arenes ChEBI polycyclic aromatic hydrocarbons ChEBI Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. 0 C6HOR5 89.072 89.00274 C1(=C(C(=C(C(=C1*)*)*)*)*)O CHEBI:13664 CHEBI:13825 CHEBI:25969 CHEBI:2857 KEGG:C15584 MetaCyc:Phenols Wikipedia:Phenols phenols chebi_ontology Aryl alcohol a phenol arenols CHEBI:33853 phenols CHEBI:33853 phenols IUPAC Aryl alcohol KEGG_COMPOUND a phenol UniProt arenols IUPAC An amino acid whose structure includes an aromatic ring. 0 C2H4NO2R 88.085 74.02420 CHEBI:13820 CHEBI:22623 CHEBI:2835 KEGG:C01021 Wikipedia:Aromatic_amino_acid Aromatic amino acid chebi_ontology aromatic amino acids CHEBI:33856 aromatic amino acid CHEBI:33856 Aromatic amino acid KEGG_COMPOUND aromatic amino acids ChEBI Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring. CHEBI:13817 CHEBI:13821 CHEBI:2830 chebi_ontology aromatic carboxylic acids CHEBI:33859 aromatic carboxylic acid CHEBI:33859 aromatic carboxylic acids ChEBI An amino compound in which the amino group is linked directly to an aromatic system. CHEBI:13827 CHEBI:22622 CHEBI:22646 CHEBI:2834 CHEBI:2863 chebi_ontology aromatic amines aryl amine aryl amines arylamine arylamines CHEBI:33860 aromatic amine CHEBI:33860 aromatic amines ChEBI aryl amine ChEBI aryl amines ChEBI arylamine ChEBI arylamines ChEBI chebi_ontology transition element coordination entities transition metal coordination compounds transition metal coordination entities CHEBI:33861 transition element coordination entity CHEBI:33861 transition element coordination entities ChEBI transition metal coordination compounds ChEBI transition metal coordination entities ChEBI A substance used in a chemical reaction to detect, measure, examine, or produce other substances. reagent chebi_ontology reactif reactivo reagents CHEBI:33893 reagent CHEBI:33893 reagent IUPAC reactif IUPAC reactivo IUPAC reagents ChEBI A hexose with a (potential) aldehyde group at one end. CHEBI:2558 aldohexose chebi_ontology aldohexoses CHEBI:33917 aldohexose CHEBI:33917 aldohexose ChEBI aldohexoses ChEBI A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. 0 C9H9N3O2 InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) TWFZGCMQGLPBSX-UHFFFAOYSA-N 191.18670 191.06948 COC(=O)Nc1nc2ccccc2[nH]1 CAS:10605-21-7 HMDB:HMDB0031769 KEGG:C10897 PMID:20833408 PMID:21315898 PMID:22077925 PMID:22903170 PPDB:116 Patent:US3010968 Pesticides:carbendazim Reaxys:649044 Wikipedia:Carbendazim Carbendazim carbendazim methyl 1H-benzimidazol-2-ylcarbamate chebi_ontology 1H-benzimidazol-2-ylcarbamic acid methyl ester 2-(Methoxy-carbonylamino)-benzimidazol 2-(methoxycarbonylamino)-benzimidazole 2-(methoxycarbonylamino)benzimidazole 2-benzimidazolecarbamic acid methyl ester BMC MBC Mecarzole carbendazime methyl 2-benzimidazolecarbamate methyl benzimidazol-2-ylcarbamate CHEBI:3392 carbendazim CHEBI:3392 CAS:10605-21-7 ChemIDplus CAS:10605-21-7 KEGG COMPOUND PMID:20833408 Europe PMC PMID:21315898 Europe PMC PMID:22077925 Europe PMC PMID:22903170 Europe PMC Pesticides:carbendazim Alan Wood's Pesticides Reaxys:649044 Reaxys Carbendazim KEGG_COMPOUND carbendazim UniProt methyl 1H-benzimidazol-2-ylcarbamate IUPAC 1H-benzimidazol-2-ylcarbamic acid methyl ester ChEBI 2-(Methoxy-carbonylamino)-benzimidazol ChemIDplus 2-(methoxycarbonylamino)-benzimidazole ChemIDplus 2-(methoxycarbonylamino)benzimidazole ChEBI 2-benzimidazolecarbamic acid methyl ester ChEBI BMC ChEBI MBC ChEBI Mecarzole KEGG_COMPOUND carbendazime ChemIDplus methyl 2-benzimidazolecarbamate ChemIDplus methyl benzimidazol-2-ylcarbamate ChemIDplus A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain. 0 C17H18N2O6S InChI=1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1 FPPNZSSZRUTDAP-UWFZAAFLSA-N 378.40070 378.08856 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(C(O)=O)c1ccccc1)C(O)=O Beilstein:1230663 CAS:4697-36-3 DrugBank:DB00578 Drug_Central:492 HMDB:HMDB0014717 KEGG:C06869 KEGG:D07614 PMID:12569987 PMID:22648337 PMID:6176550 Patent:US3142673 Reaxys:1230663 Wikipedia:Carbenicillin 6beta-(2-carboxy-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylic acid chebi_ontology (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid CBPC N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid alpha-carboxybenzylpencillin alpha-phenyl(carboxymethylpenicillin) carbenicilina carbenicillin carbenicilline carbenicillinum carboxybenzylpenicillin CHEBI:3393 carbenicillin CHEBI:3393 Beilstein:1230663 Beilstein CAS:4697-36-3 ChemIDplus CAS:4697-36-3 KEGG COMPOUND Drug_Central:492 DrugCentral PMID:12569987 Europe PMC PMID:22648337 Europe PMC PMID:6176550 Europe PMC Reaxys:1230663 Reaxys 6beta-(2-carboxy-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC CBPC ChEBI N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ChemIDplus alpha-carboxybenzylpencillin ChemIDplus alpha-phenyl(carboxymethylpenicillin) ChemIDplus carbenicilina DrugBank carbenicillin KEGG_DRUG carbenicilline DrugBank carbenicillinum DrugBank carboxybenzylpenicillin DrugBank Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals. chebi_ontology macronutrients CHEBI:33937 macronutrient CHEBI:33937 macronutrients ChEBI chebi_ontology halide salts halides CHEBI:33958 halide salt CHEBI:33958 halide salts ChEBI halides ChEBI A phenylenediamine in which the two amino groups are ortho to each other. 0 C6H8N2 InChI=1S/C6H8N2/c7-5-3-1-2-4-6(5)8/h1-4H,7-8H2 GEYOCULIXLDCMW-UHFFFAOYSA-N 108.14120 108.06875 Nc1ccccc1N Beilstein:606074 CAS:95-54-5 KEGG:C14402 PMID:23099167 PMID:23172354 PMID:23220522 PMID:23232561 PMID:23245188 PMID:23317160 PMID:23323634 PMID:23364618 PMID:23452313 PMID:2420897 PMID:9025914 Reaxys:606074 Wikipedia:O-Phenylenediamine benzene-1,2-diamine chebi_ontology 1,2-Diaminobenzene 2-Aminoaniline 2-Phenylene diamine OPDA o-Phenylenediamine phenylene-1,2-dimaine CHEBI:34043 1,2-phenylenediamine CHEBI:34043 Beilstein:606074 Beilstein CAS:95-54-5 ChemIDplus CAS:95-54-5 KEGG COMPOUND CAS:95-54-5 NIST Chemistry WebBook PMID:23099167 Europe PMC PMID:23172354 Europe PMC PMID:23220522 Europe PMC PMID:23232561 Europe PMC PMID:23245188 Europe PMC PMID:23317160 Europe PMC PMID:23323634 Europe PMC PMID:23364618 Europe PMC PMID:23452313 Europe PMC PMID:2420897 Europe PMC PMID:9025914 Europe PMC Reaxys:606074 Reaxys benzene-1,2-diamine IUPAC 1,2-Diaminobenzene KEGG_COMPOUND 2-Aminoaniline ChemIDplus 2-Phenylene diamine KEGG_COMPOUND OPDA ChemIDplus o-Phenylenediamine KEGG_COMPOUND phenylene-1,2-dimaine ChEBI An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment. 0 C12H13NO2S InChI=1S/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14) GYSSRZJIHXQEHQ-UHFFFAOYSA-N 235.300 235.06670 CC1=C(SCCO1)C(=O)NC1=CC=CC=C1 Beilstein:983249 CAS:5234-68-4 KEGG:C11255 LINCS:LSM-25660 MetaCyc:CPD0-1366 PDBeChem:CBE PMID:21228470 PMID:23047320 PMID:23261124 PMID:24119086 PMID:24785712 PMID:30724184 PMID:34065659 PMID:35182799 PMID:5386172 PMID:5487095 PMID:974232 PPDB:122 Patent:EP0042182 Pesticides:carboxin Reaxys:983249 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide chebi_ontology 2,3-Dihydro-5-carboxanilido-6-methyl-1,4-oxathiin 2,3-Dihydro-6-methyl-1,4-oxathiin-5-carboxanilide 2,3-Dihydro-6-methyl-5-phenylcarbamoyl-1,4-oxathiin 5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilide 5,6-Dihydro-2-methyl-3-carboxanilido-1,4-oxathiin 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide 5-Carboxanilido-2,3-dihydro-6-methyl-1,4-oxathiin Carbathiin Carboxine oxatin CHEBI:3405 carboxin CHEBI:3405 Beilstein:983249 ChemIDplus CAS:5234-68-4 ChemIDplus CAS:5234-68-4 KEGG COMPOUND CAS:5234-68-4 NIST Chemistry WebBook PMID:21228470 Europe PMC PMID:23047320 Europe PMC PMID:23261124 Europe PMC PMID:24119086 Europe PMC PMID:24785712 Europe PMC PMID:30724184 Europe PMC PMID:34065659 Europe PMC PMID:35182799 Europe PMC PMID:5386172 Europe PMC PMID:5487095 Europe PMC PMID:974232 Europe PMC Pesticides:carboxin Alan Wood's Pesticides Reaxys:983249 Reaxys 2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide IUPAC 2,3-Dihydro-5-carboxanilido-6-methyl-1,4-oxathiin ChemIDplus 2,3-Dihydro-6-methyl-1,4-oxathiin-5-carboxanilide NIST_Chemistry_WebBook 2,3-Dihydro-6-methyl-5-phenylcarbamoyl-1,4-oxathiin ChemIDplus 5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilide ChemIDplus 5,6-Dihydro-2-methyl-3-carboxanilido-1,4-oxathiin ChemIDplus 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide ChemIDplus 5-Carboxanilido-2,3-dihydro-6-methyl-1,4-oxathiin ChemIDplus Carbathiin ChemIDplus Carboxine ChemIDplus oxatin MetaCyc A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. 0 C9H8Cl3NO2S InChI=1S/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2 LDVVMCZRFWMZSG-UHFFFAOYSA-N 300.58900 298.93413 ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O CAS:133-06-2 KEGG:C14438 PMID:20433167 PMID:20569196 PMID:21121628 PMID:21381057 PMID:21381058 PMID:23692481 PMID:23742211 PMID:6578186 PMID:9530801 PPDB:114 Patent:US2553771 Patent:US2653155 Patent:US2713058 Pesticides:captan Wikipedia:Captan 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chebi_ontology 1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide 3a,4,7,7a-Tetrahydro-2-((trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione 3a,4,7,7a-tetrahydro-N-(trichloromethanesulphenyl)phthalimide Amercide Bangton Captab Captadin Captaf Captanex Captex ENT 26,538 Hexacap Kaptan Malipur Merpan N-(trichloromethylmercapto)-Delta(4)-tetrahydrophthalimide N-[(trichloromethyl)thio]tetrahydrophthalimide N-trichloromethylmercapto-4-cyclohexene-1,2-dicarboximide N-trichloromethylthio-3a,4,7,7a-tetrahydrophthalimide N-trichloromethylthiocyclohex-4-ene-1,2-dicarboximide Neracid Orthocide Osocide SR 406 SR406 Vanicide Venturin Vondcaptan Zenecal captane CHEBI:34608 captan CHEBI:34608 CAS:133-06-2 ChemIDplus CAS:133-06-2 KEGG COMPOUND CAS:133-06-2 NIST Chemistry WebBook PMID:20433167 Europe PMC PMID:20569196 Europe PMC PMID:21121628 Europe PMC PMID:21381057 Europe PMC PMID:21381058 Europe PMC PMID:23692481 Europe PMC PMID:23742211 Europe PMC PMID:6578186 Europe PMC PMID:9530801 Europe PMC Pesticides:captan Alan Wood's Pesticides 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione IUPAC 1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide ChemIDplus 3a,4,7,7a-Tetrahydro-2-((trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione ChemIDplus 3a,4,7,7a-tetrahydro-N-(trichloromethanesulphenyl)phthalimide ChemIDplus Amercide ChemIDplus Bangton ChemIDplus Captab ChemIDplus Captadin ChemIDplus Captaf ChemIDplus Captanex ChemIDplus Captex ChemIDplus ENT 26,538 ChemIDplus Hexacap ChemIDplus Kaptan ChemIDplus Malipur ChemIDplus Merpan ChemIDplus N-(trichloromethylmercapto)-Delta(4)-tetrahydrophthalimide ChemIDplus N-[(trichloromethyl)thio]tetrahydrophthalimide ChemIDplus N-trichloromethylmercapto-4-cyclohexene-1,2-dicarboximide ChemIDplus N-trichloromethylthio-3a,4,7,7a-tetrahydrophthalimide ChemIDplus N-trichloromethylthiocyclohex-4-ene-1,2-dicarboximide ChemIDplus Neracid ChemIDplus Orthocide ChemIDplus Osocide ChemIDplus SR 406 ChemIDplus SR406 ChemIDplus Vanicide ChemIDplus Venturin NIST_Chemistry_WebBook Vondcaptan NIST_Chemistry_WebBook Zenecal NIST_Chemistry_WebBook captane ChemIDplus An indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. 0 C32H22N6Na2O6S2 C32H22N6O6S2.2Na InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2 IQFVPQOLBLOTPF-UHFFFAOYSA-L 696.667 696.08376 C1=CC(C2=CC=C(N=NC3=CC(=C4C(=C3N)C=CC=C4)S([O-])(=O)=O)C=C2)=CC=C1N=NC5=CC(=C6C(=C5N)C=CC=C6)S([O-])(=O)=O.[Na+].[Na+] Beilstein:3894858 Beilstein:741468 CAS:573-58-0 Gmelin:135213 KEGG:C14078 Congo red disodium 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) chebi_ontology Direct red 28 Kongorot Sodium diphenyldiazo-bis-alpha-naphthylaminesulfonate disodium 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-aminonaphthalene-1-sulphonate) CHEBI:34653 Congo Red CHEBI:34653 Beilstein:3894858 Beilstein Beilstein:741468 Beilstein CAS:573-58-0 ChemIDplus CAS:573-58-0 KEGG COMPOUND Gmelin:135213 Gmelin Congo red KEGG_COMPOUND disodium 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) IUPAC Direct red 28 KEGG_COMPOUND Kongorot ChemIDplus Sodium diphenyldiazo-bis-alpha-naphthylaminesulfonate KEGG_COMPOUND disodium 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-aminonaphthalene-1-sulphonate) ChemIDplus A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. 0 C15H14ClN3O4S InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1 QYIYFLOTGYLRGG-GPCCPHFNSA-N 367.80700 367.03935 [H][C@]12SCC(Cl)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O CHEBI:472656 Beilstein:3632473 CAS:53994-73-3 DrugBank:DB00833 Drug_Central:525 HMDB:HMDB0014971 KEGG:C06877 KEGG:D00256 LINCS:LSM-5368 PMID:10230635 PMID:10930630 PMID:11963587 PMID:12485718 PMID:12569987 PMID:15812119 PMID:18969055 PMID:29017833 Patent:DE2408698 Patent:US3925372 Reaxys:3632473 Wikipedia:Cefaclor (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-3,4-didehydrocepham-4-carboxylic acid Cefaclor cefaclor chebi_ontology 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid CCL Cefaclor anhydrous Cephaclor cefaclorum CHEBI:3478 cefaclor CHEBI:3478 Beilstein:3632473 Beilstein CAS:53994-73-3 ChemIDplus CAS:53994-73-3 DrugBank CAS:53994-73-3 KEGG COMPOUND CAS:53994-73-3 KEGG DRUG Drug_Central:525 DrugCentral PMID:10230635 ChEMBL PMID:10930630 Europe PMC PMID:11963587 Europe PMC PMID:12485718 Europe PMC PMID:12569987 Europe PMC PMID:15812119 Europe PMC PMID:18969055 Europe PMC PMID:29017833 Europe PMC Reaxys:3632473 Reaxys (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC 7beta-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-3,4-didehydrocepham-4-carboxylic acid IUPAC Cefaclor KEGG_COMPOUND cefaclor ChEMBL 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid ChemIDplus CCL KEGG_DRUG Cefaclor anhydrous ChemIDplus Cephaclor ChemIDplus cefaclorum DrugBank A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms. 0 C17H17N7O8S4 InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1 SRZNHPXWXCNNDU-IXOPCIAXSA-N 575.61900 575.00215 [H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)C1SC(S1)=C(C(N)=O)C(O)=O)OC)C(O)=O CHEBI:558729 Beilstein:5697364 CAS:69712-56-7 DrugBank:DB01330 Drug_Central:547 KEGG:C06886 KEGG:D00260 LINCS:LSM-5961 PMID:17664321 PMID:29017833 Patent:DE2824559 Patent:US4263432 Reaxys:5697364 Wikipedia:Cefotetan (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid Cefotetan cefotetan chebi_ontology (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid cefotetan cefotetanum CHEBI:3499 cefotetan CHEBI:3499 Beilstein:5697364 Beilstein CAS:69712-56-7 ChemIDplus CAS:69712-56-7 KEGG COMPOUND Drug_Central:547 DrugCentral PMID:17664321 ChEMBL PMID:29017833 Europe PMC Reaxys:5697364 Reaxys (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC 7beta-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid IUPAC Cefotetan KEGG_COMPOUND cefotetan ChEMBL (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid ChemIDplus cefotetan ChemIDplus cefotetanum ChemIDplus Any of the glycopeptides whose structure consists of teicoplanin A3-1 in which the hydroxy group of the di(aryloxy)-substituted phenol moiety has been converted to the corresponding 2-acylamino-2-deoxy-beta-D-glucoside. Members of the class differ only in the nature of the acyl group. 0 C79H78Cl2N9O33R 1752.414 1750.40791 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H]2NC(=O)[C@H](NC(=O)[C@@H]3NC(=O)[C@H]4NC(=O)[C@@H](Cc5ccc(Oc6cc3cc(Oc3ccc1cc3Cl)c6O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC([*])=O)c(Cl)c5)NC(=O)[C@H](N)c1ccc(O)c(Oc3cc(O)cc4c3)c1)c1ccc(O)c(c1)-c1c(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc(O)cc1[C@H](NC2=O)C(O)=O KEGG:C13781 chebi_ontology teicoplanin A2-* CHEBI:34994 teicoplanin A2 CHEBI:34994 teicoplanin A2-* ChEBI A teicoplanin A2 that has (4Z)-dec-4-enoyl as the variable N-acyl group. 0 C88H95Cl2N9O33 InChI=1S/C88H95Cl2N9O33/c1-3-4-5-6-7-8-9-10-60(108)131-78-75(114)72(111)57(31-100)127-85(78)99-67-55-26-40-27-56(67)126-52-18-14-38(24-47(52)90)77(132-87-68(92-34(2)103)73(112)70(109)58(32-101)129-87)69-84(121)97-66(86(122)123)45-29-42(105)30-54(128-88-76(115)74(113)71(110)59(33-102)130-88)61(45)44-23-37(13-15-49(44)106)63(81(118)98-69)95-83(120)65(40)96-82(119)64-39-21-41(104)28-43(22-39)124-53-25-36(12-16-50(53)107)62(91)80(117)93-48(79(116)94-64)20-35-11-17-51(125-55)46(89)19-35/h7-8,11-19,21-30,48,57-59,62-66,68-78,85,87-88,99-102,104-107,109-115H,3-6,9-10,20,31-33,91H2,1-2H3,(H,92,103)(H,93,117)(H,94,116)(H,95,120)(H,96,119)(H,97,121)(H,98,118)(H,122,123)/b8-7-/t48-,57-,58-,59-,62-,63-,64+,65-,66+,68-,69+,70-,71-,72-,73-,74+,75+,76+,77-,78-,85-,87+,88+/m1/s1 SGSMSXWFVXNLOG-UCNABHHISA-N 1877.64200 1875.54093 CCCCC\C=C/CCC(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Nc1c2Oc3ccc(C[C@H]4NC(=O)[C@H](N)c5ccc(O)c(Oc6cc(O)cc(c6)[C@H](NC4=O)C(=O)N[C@@H]4c(c2)cc1Oc1ccc(cc1Cl)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)[C@@H]1NC(=O)[C@H](NC4=O)c2ccc(O)c(c2)-c2c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc(O)cc2[C@H](NC1=O)C(O)=O)c5)cc3Cl CAS:91032-34-7 KEGG:C13587 Reaxys:6261779 Teicoplanin A2-1 chebi_ontology (Z)-34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone (Z)-34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxo-4-decenyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone Teichomycin A2 factor 1 CHEBI:34995 teicoplanin A2-1 CHEBI:34995 CAS:91032-34-7 ChemIDplus CAS:91032-34-7 KEGG COMPOUND Reaxys:6261779 Reaxys Teicoplanin A2-1 KEGG_COMPOUND (Z)-34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus (Z)-34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxo-4-decenyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI Teichomycin A2 factor 1 KEGG_COMPOUND A teicoplanin A2 that has decanoyl as the variable N-acyl group. 0 C88H97Cl2N9O33 InChI=1S/C88H97Cl2N9O33/c1-3-4-5-6-7-8-9-10-60(108)94-68-74(113)71(110)58(32-101)129-87(68)132-78-55-26-40-27-56(78)126-52-18-14-38(24-47(52)90)77(131-86-67(92-34(2)103)73(112)70(109)57(31-100)128-86)69-84(121)98-66(85(122)123)45-29-42(105)30-54(127-88-76(115)75(114)72(111)59(33-102)130-88)61(45)44-23-37(13-15-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-21-41(104)28-43(22-39)124-53-25-36(12-16-50(53)107)62(91)80(117)93-48(79(116)95-64)20-35-11-17-51(125-55)46(89)19-35/h11-19,21-30,48,57-59,62-77,86-88,100-102,104-107,109-115H,3-10,20,31-33,91H2,1-2H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/t48-,57-,58-,59-,62-,63-,64+,65-,66+,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1 BJNLLBUOHPVGFT-PKMGYIMSSA-N 1879.65800 1877.55658 CCCCCCCCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(C[C@H]4NC(=O)[C@H](N)c5ccc(O)c(Oc6cc(O)cc(c6)[C@H](NC4=O)C(=O)N[C@@H]4c(c2)cc1Oc1ccc(cc1Cl)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)[C@@H]1NC(=O)[C@H](NC4=O)c2ccc(O)c(c2)-c2c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc(O)cc2[C@H](NC1=O)C(O)=O)c5)cc3Cl CAS:91032-36-9 KEGG:C13588 Reaxys:6995259 Teicoplanin A2-3 chebi_ontology 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone Teichomycin A2 factor 3 CHEBI:34996 teicoplanin A2-3 CHEBI:34996 CAS:91032-36-9 ChemIDplus CAS:91032-36-9 KEGG COMPOUND Reaxys:6995259 Reaxys Teicoplanin A2-3 KEGG_COMPOUND 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI Teichomycin A2 factor 3 KEGG_COMPOUND A teicoplanin A2 that has 8-methyldecanoyl as the variable N-acyl group. 0 C89H99Cl2N9O33 InChI=1S/C89H99Cl2N9O33/c1-4-34(2)9-7-5-6-8-10-61(109)95-69-75(114)72(111)59(32-102)130-88(69)133-79-56-26-41-27-57(79)127-53-18-14-39(24-48(53)91)78(132-87-68(93-35(3)104)74(113)71(110)58(31-101)129-87)70-85(122)99-67(86(123)124)46-29-43(106)30-55(128-89-77(116)76(115)73(112)60(33-103)131-89)62(46)45-23-38(13-15-50(45)107)64(82(119)100-70)97-84(121)66(41)98-83(120)65-40-21-42(105)28-44(22-40)125-54-25-37(12-16-51(54)108)63(92)81(118)94-49(80(117)96-65)20-36-11-17-52(126-56)47(90)19-36/h11-19,21-30,34,49,58-60,63-78,87-89,101-103,105-108,110-116H,4-10,20,31-33,92H2,1-3H3,(H,93,104)(H,94,118)(H,95,109)(H,96,117)(H,97,121)(H,98,120)(H,99,122)(H,100,119)(H,123,124)/t34?,49-,58-,59-,60-,63-,64-,65+,66-,67+,68-,69-,70+,71-,72-,73-,74-,75-,76+,77+,78-,87+,88+,89+/m1/s1 KSPOYQQCANXEDC-WNTLLCOUSA-N 1893.68500 1891.57223 CCC(C)CCCCCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(C[C@H]4NC(=O)[C@H](N)c5ccc(O)c(Oc6cc(O)cc(c6)[C@H](NC4=O)C(=O)N[C@@H]4c(c2)cc1Oc1ccc(cc1Cl)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)[C@@H]1NC(=O)[C@H](NC4=O)c2ccc(O)c(c2)-c2c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc(O)cc2[C@H](NC1=O)C(O)=O)c5)cc3Cl CAS:91032-37-0 KEGG:C13610 Reaxys:6261978 Teicoplanin A2-4 chebi_ontology 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(8-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone Teichomycin A2 factor 4 CHEBI:34997 teicoplanin A2-4 CHEBI:34997 CAS:91032-37-0 ChemIDplus CAS:91032-37-0 KEGG COMPOUND Reaxys:6261978 Reaxys Teicoplanin A2-4 KEGG_COMPOUND 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(8-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI Teichomycin A2 factor 4 KEGG_COMPOUND A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group. 0 C89H99Cl2N9O33 InChI=1S/C89H99Cl2N9O33/c1-34(2)9-7-5-4-6-8-10-61(109)95-69-75(114)72(111)59(32-102)130-88(69)133-79-56-26-41-27-57(79)127-53-18-14-39(24-48(53)91)78(132-87-68(93-35(3)104)74(113)71(110)58(31-101)129-87)70-85(122)99-67(86(123)124)46-29-43(106)30-55(128-89-77(116)76(115)73(112)60(33-103)131-89)62(46)45-23-38(13-15-50(45)107)64(82(119)100-70)97-84(121)66(41)98-83(120)65-40-21-42(105)28-44(22-40)125-54-25-37(12-16-51(54)108)63(92)81(118)94-49(80(117)96-65)20-36-11-17-52(126-56)47(90)19-36/h11-19,21-30,34,49,58-60,63-78,87-89,101-103,105-108,110-116H,4-10,20,31-33,92H2,1-3H3,(H,93,104)(H,94,118)(H,95,109)(H,96,117)(H,97,121)(H,98,120)(H,99,122)(H,100,119)(H,123,124)/t49-,58-,59-,60-,63-,64-,65+,66-,67+,68-,69-,70+,71-,72-,73-,74-,75-,76+,77+,78-,87+,88+,89+/m1/s1 FHBQKTSCJKPYIO-RLDSMAAISA-N 1893.68500 1891.57223 CC(C)CCCCCCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(C[C@H]4NC(=O)[C@H](N)c5ccc(O)c(Oc6cc(O)cc(c6)[C@H](NC4=O)C(=O)N[C@@H]4c(c2)cc1Oc1ccc(cc1Cl)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)[C@@H]1NC(=O)[C@H](NC4=O)c2ccc(O)c(c2)-c2c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc(O)cc2[C@H](NC1=O)C(O)=O)c5)cc3Cl CAS:91032-38-1 KEGG:C13612 Reaxys:6995322 Reaxys:7509352 Teicoplanin A2-5 chebi_ontology 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone Teichomycin A2 factor 5 CHEBI:34998 teicoplanin A2-5 CHEBI:34998 CAS:91032-38-1 ChemIDplus CAS:91032-38-1 KEGG COMPOUND Reaxys:6995322 Reaxys Reaxys:7509352 Reaxys Teicoplanin A2-5 KEGG_COMPOUND 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI Teichomycin A2 factor 5 KEGG_COMPOUND A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido-2-deoxy-beta-D-glucoside. 0 C72H68Cl2N8O28 InChI=1S/C72H68Cl2N8O28/c1-24(85)76-55-60(93)58(91)47(22-83)108-71(55)110-63-28-5-9-42(37(74)15-28)106-46-18-30-17-45(57(46)90)105-41-8-2-25(10-36(41)73)11-38-64(96)78-52(29-12-31(86)19-33(13-29)104-43-16-26(3-7-40(43)89)50(75)65(97)77-38)67(99)80-53(30)68(100)79-51-27-4-6-39(88)34(14-27)49-35(54(70(102)103)81-69(101)56(63)82-66(51)98)20-32(87)21-44(49)107-72-62(95)61(94)59(92)48(23-84)109-72/h2-10,12-21,38,47-48,50-56,58-63,71-72,83-84,86-95H,11,22-23,75H2,1H3,(H,76,85)(H,77,97)(H,78,96)(H,79,100)(H,80,99)(H,81,101)(H,82,98)(H,102,103)/t38-,47-,48-,50-,51-,52+,53-,54+,55-,56+,58-,59-,60-,61+,62+,63-,71+,72+/m1/s1 SUFIXUDUKRJOBH-JSMFNTJWSA-N 1564.25300 1562.35201 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H]2NC(=O)[C@H](NC(=O)[C@@H]3NC(=O)[C@H]4NC(=O)[C@@H](Cc5ccc(Oc6cc3cc(Oc3ccc1cc3Cl)c6O)c(Cl)c5)NC(=O)[C@H](N)c1ccc(O)c(Oc3cc(O)cc4c3)c1)c1ccc(O)c(c1)-c1c(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc(O)cc1[C@H](NC2=O)C(O)=O CAS:93616-27-4 KEGG:C13613 PMID:1416858 Reaxys:6267420 Teicoplanin A3-1 chebi_ontology 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone CHEBI:34999 teicoplanin A3-1 CHEBI:34999 CAS:93616-27-4 ChemIDplus CAS:93616-27-4 KEGG COMPOUND PMID:1416858 Europe PMC Reaxys:6267420 Reaxys Teicoplanin A3-1 KEGG_COMPOUND 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI A member of the class of thioureas that is the dimethyl ester of (1,2-phenylenedicarbamothioyl)biscarbamic acid. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould. 0 C12H14N4O4S2 InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) QGHREAKMXXNCOA-UHFFFAOYSA-N 342.39400 342.04565 COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC CAS:23564-05-8 KEGG:C14432 PMID:22057426 PMID:22667099 PMID:23242258 PMID:23775824 PMID:23978278 PMID:24256946 PMID:24366405 PPDB:640 Pesticides:thiophanate-methyl Reaxys:937942 dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate chebi_ontology 1,2-Bis(3-(methoxycarbonyl)-2-thioureido)benzene 1,2-Bis(methoxycarbonylthioureido)benzene 1,2-Di-(3-methoxycarbonyl-2-thioureido)benzene Methyl thiophanate Methylthiofanate Methylthiophanate dimethyl 4,4'-(o-phenylene)bis(3-thioallophanate) dimethyl N,N'-[1,2-phenylenebis(azanediylcarbonothioyl)]dicarbamate dimethyl N,N'-[1,2-phenylenebis(iminocarbonothioyl)]bis[carbamate] o-Bis(3-methoxycarbonyl-2-thioureido)benzene CHEBI:35014 thiophanate-methyl CHEBI:35014 CAS:23564-05-8 ChemIDplus CAS:23564-05-8 KEGG COMPOUND PMID:22057426 Europe PMC PMID:22667099 Europe PMC PMID:23242258 Europe PMC PMID:23775824 Europe PMC PMID:23978278 Europe PMC PMID:24256946 Europe PMC PMID:24366405 Europe PMC Pesticides:thiophanate-methyl Alan Wood's Pesticides Reaxys:937942 Reaxys dimethyl (1,2-phenylenedicarbamothioyl)biscarbamate IUPAC 1,2-Bis(3-(methoxycarbonyl)-2-thioureido)benzene ChemIDplus 1,2-Bis(methoxycarbonylthioureido)benzene ChemIDplus 1,2-Di-(3-methoxycarbonyl-2-thioureido)benzene ChemIDplus 1,2-Di-(3-methoxycarbonyl-2-thioureido)benzene KEGG_COMPOUND Methyl thiophanate ChemIDplus Methylthiofanate ChemIDplus Methylthiophanate ChemIDplus dimethyl 4,4'-(o-phenylene)bis(3-thioallophanate) Alan_Wood's_Pesticides dimethyl N,N'-[1,2-phenylenebis(azanediylcarbonothioyl)]dicarbamate Alan_Wood's_Pesticides dimethyl N,N'-[1,2-phenylenebis(iminocarbonothioyl)]bis[carbamate] Alan_Wood's_Pesticides o-Bis(3-methoxycarbonyl-2-thioureido)benzene ChemIDplus A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis. 0 C15H17N5O6S2 InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1 WYUSVOMTXWRGEK-HBWVYFAYSA-N 427.45500 427.06203 [H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O CHEBI:606443 Beilstein:6021381 CAS:80210-62-4 DrugBank:DB01416 KEGG:C08114 KEGG:D07650 PMID:20606336 PMID:20821175 PMID:21395603 PMID:21420838 PMID:21455420 PMID:21509928 PMID:21569093 PMID:21667000 PMID:29017833 Reaxys:6021381 VSDB:2968 Wikipedia:Cefpodoxime 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefpodoxima cefpodoxime cefpodoximum CHEBI:3504 cefpodoxime CHEBI:3504 Beilstein:6021381 Beilstein CAS:80210-62-4 ChemIDplus CAS:80210-62-4 KEGG COMPOUND PMID:20606336 Europe PMC PMID:20821175 Europe PMC PMID:21395603 Europe PMC PMID:21420838 Europe PMC PMID:21455420 Europe PMC PMID:21509928 Europe PMC PMID:21569093 Europe PMC PMID:21667000 Europe PMC PMID:29017833 Europe PMC Reaxys:6021381 Reaxys 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid IUPAC (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC cefpodoxima ChemIDplus cefpodoxime ChemIDplus cefpodoximum ChemIDplus The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis. 0 C21H27N5O9S2 InChI=1S/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1 LTINZAODLRIQIX-FBXRGJNPSA-N 557.59700 557.12502 [H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(=O)OC(C)OC(=O)OC(C)C Beilstein:8174918 CAS:87239-81-4 DrugBank:DB01416 Drug_Central:555 KEGG:C08115 KEGG:D00920 Patent:EP49118 Patent:US4486425 1-{[(propan-2-yloxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 1-{[(propan-2-yloxy)carbonyl]oxy}ethyl 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylate chebi_ontology (RS)-1-((isopropoxycarbonyl)oxy)ethyl (+)-(6R,7R)-7-(2-(2-amino-4-thiazolyl)-2-((Z)-methoxyimino)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester CHEBI:3505 cefpodoxime proxetil CHEBI:3505 Beilstein:8174918 Beilstein CAS:87239-81-4 ChemIDplus CAS:87239-81-4 KEGG COMPOUND Drug_Central:555 DrugCentral 1-{[(propan-2-yloxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC 1-{[(propan-2-yloxy)carbonyl]oxy}ethyl 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylate IUPAC (RS)-1-((isopropoxycarbonyl)oxy)ethyl (+)-(6R,7R)-7-(2-(2-amino-4-thiazolyl)-2-((Z)-methoxyimino)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate ChemIDplus cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester ChEBI A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. 0 C22H22N6O7S2 InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1 ORFOPKXBNMVMKC-DWVKKRMSSA-N 546.57600 546.09914 [H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C(O)=O)\c1csc(N)n1)C([O-])=O Beilstein:5475149 CAS:72558-82-8 DrugBank:DB00438 KEGG:C06889 KEGG:D07654 PMID:11252323 PMID:11284241 PMID:11591698 PMID:11605815 PMID:11815759 PMID:12048030 PMID:12120880 PMID:12523657 PMID:12767750 PMID:12833570 PMID:1384868 PMID:14961139 PMID:15528892 PMID:15618675 PMID:15687217 PMID:15913752 PMID:16092041 PMID:16501927 PMID:16956383 PMID:18611568 PMID:18926104 PMID:19810175 PMID:1991925 PMID:2068466 PMID:24089577 PMID:2570956 PMID:28543395 Patent:DE2921316 Patent:US4258041 Reaxys:5475149 Wikipedia:Ceftazidime 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate chebi_ontology (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CAZ Ceftazidime anhydrous ceftazidima ceftazidime ceftazidimum CHEBI:3508 ceftazidime CHEBI:3508 Beilstein:5475149 Beilstein CAS:72558-82-8 ChemIDplus CAS:72558-82-8 KEGG COMPOUND CAS:72558-82-8 KEGG DRUG PMID:11252323 Europe PMC PMID:11284241 Europe PMC PMID:11591698 Europe PMC PMID:11605815 Europe PMC PMID:11815759 Europe PMC PMID:12048030 Europe PMC PMID:12120880 Europe PMC PMID:12523657 Europe PMC PMID:12767750 Europe PMC PMID:12833570 Europe PMC PMID:1384868 Europe PMC PMID:14961139 Europe PMC PMID:15528892 Europe PMC PMID:15618675 Europe PMC PMID:15687217 Europe PMC PMID:15913752 Europe PMC PMID:16092041 Europe PMC PMID:16501927 Europe PMC PMID:16956383 Europe PMC PMID:18611568 Europe PMC PMID:18926104 Europe PMC PMID:19810175 Europe PMC PMID:1991925 Europe PMC PMID:2068466 Europe PMC PMID:24089577 Europe PMC PMID:2570956 Europe PMC PMID:28543395 Europe PMC Reaxys:5475149 Reaxys 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate IUPAC (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC CAZ KEGG_DRUG Ceftazidime anhydrous ChemIDplus ceftazidima DrugBank ceftazidime KEGG_DRUG ceftazidimum DrugBank chebi_ontology nitrogen hydrides CHEBI:35106 nitrogen hydride CHEBI:35106 nitrogen hydrides ChEBI Saturated acyclic nitrogen hydrides having the general formula NnHn+2. chebi_ontology azanes CHEBI:35107 azane CHEBI:35107 azanes ChEBI manganese coordination entity chebi_ontology manganese coordination compounds manganese coordination entities CHEBI:35117 manganese coordination entity CHEBI:35117 manganese coordination entity ChEBI manganese coordination compounds ChEBI manganese coordination entities ChEBI chebi_ontology aldose phosphates CHEBI:35131 aldose phosphate CHEBI:35131 aldose phosphates ChEBI A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain. 0 C16H16N4O8S InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 JFPVXVDWJQMJEE-IZRZKJBUSA-N 424.38640 424.06888 [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1ccco1)C(O)=O CAS:55268-75-2 DrugBank:DB01112 Drug_Central:565 KEGG:C06894 KEGG:D00262 MetaCyc:CPD0-2069 PMID:11168076 PMID:11322179 PMID:11581233 PMID:12141712 PMID:12235459 PMID:12833570 PMID:12898829 PMID:14658923 PMID:15052582 PMID:15828440 PMID:16341950 PMID:17111749 PMID:17113884 PMID:17261579 PMID:17366015 PMID:17676080 PMID:18208759 PMID:18611587 PMID:18795089 PMID:18931469 PMID:19069618 PMID:19142482 PMID:19411164 PMID:21425867 PMID:29017833 Patent:DE2439880 Patent:DE2706413 Patent:US3974153 Patent:US4267320 Reaxys:5783190 Wikipedia:Cefuroxime 3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid Cefuroxime chebi_ontology (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cefuroxim Cephuroxime Sharox Zinacef Danmark cefuroxime cefuroximo cefuroximum CHEBI:3515 cefuroxime CHEBI:3515 CAS:55268-75-2 ChemIDplus CAS:55268-75-2 KEGG COMPOUND Drug_Central:565 DrugCentral PMID:11168076 Europe PMC PMID:11322179 Europe PMC PMID:11581233 Europe PMC PMID:12141712 Europe PMC PMID:12235459 Europe PMC PMID:12833570 Europe PMC PMID:12898829 Europe PMC PMID:14658923 Europe PMC PMID:15052582 Europe PMC PMID:15828440 Europe PMC PMID:16341950 Europe PMC PMID:17111749 Europe PMC PMID:17113884 Europe PMC PMID:17261579 Europe PMC PMID:17366015 Europe PMC PMID:17676080 Europe PMC PMID:18208759 Europe PMC PMID:18611587 Europe PMC PMID:18795089 Europe PMC PMID:18931469 Europe PMC PMID:19069618 Europe PMC PMID:19142482 Europe PMC PMID:19411164 Europe PMC PMID:21425867 Europe PMC PMID:29017833 Europe PMC Reaxys:5783190 Reaxys 3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid IUPAC Cefuroxime KEGG_COMPOUND (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC Cefuroxim ChemIDplus Cephuroxime ChemIDplus Sharox ChemIDplus Zinacef Danmark ChemIDplus cefuroxime ChemIDplus cefuroximo ChemIDplus cefuroximum ChemIDplus chebi_ontology sulfate salts sulfates sulphate salts sulphates CHEBI:35175 sulfate salt CHEBI:35175 sulfate salts ChEBI sulfates ChEBI sulphate salts ChEBI sulphates ChEBI A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]. terpene terpenes chebi_ontology Terpen terpenes terpeno terpenos CHEBI:35186 terpene CHEBI:35186 terpene IUPAC terpenes IUPAC Terpen ChEBI terpenes IUPAC terpeno IUPAC terpenos IUPAC A C15 terpene. sesquiterpenes chebi_ontology Sesquiterpen sesquiterpenes sesquiterpeno sesquiterpenos CHEBI:35189 sesquiterpene CHEBI:35189 sesquiterpenes IUPAC Sesquiterpen ChEBI sesquiterpenes IUPAC sesquiterpeno IUPAC sesquiterpenos IUPAC A C20 terpene. diterpenes chebi_ontology Diterpen diterpenes diterpeno diterpenos CHEBI:35190 diterpene CHEBI:35190 diterpenes IUPAC Diterpen ChEBI diterpenes IUPAC diterpeno IUPAC diterpenos IUPAC A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. surfactant chebi_ontology surface active agent surfactants CHEBI:35195 surfactant CHEBI:35195 surfactant IUPAC surface active agent IUPAC surfactants ChEBI A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring. cyclodepsipeptides chebi_ontology Cyclodepsipeptid Zyklodepsipeptid CHEBI:35213 cyclodepsipeptide CHEBI:35213 cyclodepsipeptides IUPAC Cyclodepsipeptid ChEBI Zyklodepsipeptid ChEBI A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. Wikipedia:Antimetabolite antimetabolite chebi_ontology antimetabolites CHEBI:35221 antimetabolite CHEBI:35221 antimetabolite IUPAC antimetabolites ChEBI A substance that diminishes the rate of a chemical reaction. inhibitor chebi_ontology inhibidor inhibiteur inhibitors CHEBI:35222 inhibitor CHEBI:35222 inhibitor IUPAC inhibidor ChEBI inhibiteur ChEBI inhibitors ChEBI A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. catalyst chebi_ontology Katalysator catalizador catalyseur CHEBI:35223 catalyst CHEBI:35223 catalyst IUPAC Katalysator ChEBI catalizador ChEBI catalyseur ChEBI The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group. amino acid zwitterion chebi_ontology CHEBI:35238 amino acid zwitterion CHEBI:35238 amino acid zwitterion ChEBI An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of serine. 0 C3H7NO3 InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7) MTCFGRXMJLQNBG-UHFFFAOYSA-N 105.09262 105.04259 [NH3+]C(CO)C([O-])=O Beilstein:3935647 Gmelin:2060272 2-ammonio-3-hydroxypropanoate serine zwitterion chebi_ontology CHEBI:35243 serine zwitterion CHEBI:35243 Beilstein:3935647 Beilstein Gmelin:2060272 Gmelin 2-ammonio-3-hydroxypropanoate IUPAC serine zwitterion IUPAC A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups. +1 NR4 14.00670 14.00307 [*][N+]([*])([*])[*] CHEBI:26470 CHEBI:8693 KEGG:C06703 quaternary ammonium ion chebi_ontology Quaternary amine a quaternary ammonium quaternary ammonium ions CHEBI:35267 quaternary ammonium ion CHEBI:35267 quaternary ammonium ion IUPAC Quaternary amine KEGG_COMPOUND a quaternary ammonium UniProt quaternary ammonium ions ChEBI A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc). chebi_ontology ammonium ion derivatives azanium ion derivative azanium ion derivatives CHEBI:35274 ammonium ion derivative CHEBI:35274 ammonium ion derivatives ChEBI azanium ion derivative ChEBI azanium ion derivatives ChEBI A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and a S atom bound to a carbon atom, thus creating a C-S bond. CHEBI:22048 CHEBI:33577 S-glycosyl compound chebi_ontology S-glycoside S-glycosides S-glycosyl compounds thioglycoside thioglycosides CHEBI:35275 S-glycosyl compound CHEBI:35275 S-glycosyl compound ChEBI S-glycoside ChEBI S-glycosides ChEBI S-glycosyl compounds ChEBI thioglycoside JCBN thioglycosides JCBN Compounds (NH4(+))Y(-) and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups. azanium compounds chebi_ontology ammonium compounds CHEBI:35276 ammonium compound CHEBI:35276 azanium compounds IUPAC ammonium compounds ChEBI ammonium compounds IUPAC Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. betaines chebi_ontology onium betaines CHEBI:35281 onium betaine CHEBI:35281 betaines IUPAC onium betaines ChEBI chebi_ontology iminium betaines CHEBI:35285 iminium betaine CHEBI:35285 iminium betaines ChEBI Cations of structure R2C=N(+)R2. iminium ion chebi_ontology iminium cations iminium ions CHEBI:35286 iminium ion CHEBI:35286 iminium ion ChEBI iminium cations ChEBI iminium ions ChEBI A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are adjacent to each other. chebi_ontology fused compounds fused polycyclic compounds fused-ring polycyclic compound fused-ring polycyclic compounds polycyclic fused-ring compounds CHEBI:35293 fused compound CHEBI:35293 fused compounds ChEBI fused polycyclic compounds ChEBI fused-ring polycyclic compound ChEBI fused-ring polycyclic compounds ChEBI polycyclic fused-ring compounds ChEBI A polyclic compound in which all of the ring members are carbon atoms. chebi_ontology carbopolycyclic compounds CHEBI:35294 carbopolycyclic compound CHEBI:35294 carbopolycyclic compounds ChEBI chebi_ontology homopolycyclic compounds CHEBI:35295 homopolycyclic compound CHEBI:35295 homopolycyclic compounds ChEBI chebi_ontology ortho-fused polycyclic arenes CHEBI:35296 ortho-fused polycyclic arene CHEBI:35296 ortho-fused polycyclic arenes ChEBI A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement. 0 C10H8.(C4H2)n Wikipedia:Acene acene acenes chebi_ontology Acen Azen polyacenes CHEBI:35297 acene CHEBI:35297 acene IUPAC acenes IUPAC Acen ChEBI Azen ChEBI polyacenes ChEBI pentoside chebi_ontology pentosides CHEBI:35312 pentoside CHEBI:35312 pentoside ChEBI pentosides ChEBI hexoside chebi_ontology hexosides CHEBI:35313 hexoside CHEBI:35313 hexoside ChEBI hexosides ChEBI A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract. 0 C16H17N3O4S InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 347.38900 347.09398 [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O Beilstein:965503 CAS:15686-71-2 DrugBank:DB00567 Drug_Central:571 HMDB:HMDB0014707 KEGG:C06895 KEGG:D00263 LINCS:LSM-5957 PMID:10930630 PMID:12569987 PMID:12833570 PMID:1384868 PMID:2083978 PMID:22559990 PMID:23061564 PMID:23457080 PMID:23545436 PMID:23688276 PMID:23811740 PMID:24268227 PMID:24548092 PMID:29017833 Patent:US3275626 Patent:US3507861 Reaxys:4238892 VSDB:1791 Wikipedia:Cefalexin 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid CEX Cefalexin Celexin Cepastar Cepexin Cephacillin Ceporexin cefalexina cefalexine cefalexinum CHEBI:3534 cephalexin CHEBI:3534 Beilstein:965503 Beilstein CAS:15686-71-2 ChemIDplus CAS:15686-71-2 KEGG COMPOUND Drug_Central:571 DrugCentral PMID:10930630 Europe PMC PMID:12569987 Europe PMC PMID:12833570 Europe PMC PMID:1384868 Europe PMC PMID:2083978 Europe PMC PMID:22559990 Europe PMC PMID:23061564 Europe PMC PMID:23457080 Europe PMC PMID:23545436 Europe PMC PMID:23688276 Europe PMC PMID:23811740 Europe PMC PMID:24268227 Europe PMC PMID:24548092 Europe PMC PMID:29017833 Europe PMC Reaxys:4238892 Reaxys 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid IUPAC (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid ChemIDplus 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ChemIDplus CEX KEGG_DRUG Cefalexin KEGG_COMPOUND Celexin ChemIDplus Cepastar ChemIDplus Cepexin ChemIDplus Cephacillin ChemIDplus Ceporexin ChemIDplus cefalexina ChemIDplus cefalexine ChemIDplus cefalexinum ChemIDplus Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. 0 C19H31R 259.450 259.24258 C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C CHEBI:13687 CHEBI:26768 CHEBI:9263 KEGG:C00377 MetaCyc:Steroids Steroid steroids chebi_ontology a steroid CHEBI:35341 steroid CHEBI:35341 Steroid KEGG_COMPOUND steroids IUPAC a steroid UniProt CHEBI:24748 CHEBI:5814 KEGG:C02159 chebi_ontology Hydroxysteroid hydroxy steroids hydroxysteroids CHEBI:35350 hydroxy steroid CHEBI:35350 Hydroxysteroid KEGG_COMPOUND hydroxy steroids ChEBI hydroxysteroids ChEBI Any heteroorganic entity containing at least one carbon-nitrogen bond. organonitrogen compounds chebi_ontology organonitrogens CHEBI:35352 organonitrogen compound CHEBI:35352 organonitrogen compounds IUPAC organonitrogens ChEBI An imide in which the two acyl substituents on nitrogen are carboacyl groups. 0 C2NO2R3 70.027 69.99290 [*]N(C([*])=O)C([*])=O chebi_ontology dicarboximides CHEBI:35356 dicarboximide CHEBI:35356 dicarboximides ChEBI An amide of a sulfonic acid RS(=O)2NR'2. 0 NO2SR3 78.07100 77.96497 [*]S(=O)(=O)N([*])[*] PMID:11498380 PMID:2434548 PMID:26811268 PMID:26832216 Wikipedia:Sulfonamide sulfonamides chebi_ontology sulfonamides CHEBI:35358 sulfonamide CHEBI:35358 PMID:11498380 Europe PMC PMID:2434548 Europe PMC PMID:26811268 Europe PMC PMID:26832216 Europe PMC sulfonamides IUPAC sulfonamides ChEBI Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom. KEGG:C06060 carboxamidines chebi_ontology Amidines carboxamidines CHEBI:35359 carboxamidine CHEBI:35359 carboxamidines IUPAC Amidines KEGG_COMPOUND carboxamidines ChEBI Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC). hydrazides chebi_ontology hydrazides CHEBI:35362 hydrazide CHEBI:35362 hydrazides IUPAC hydrazides ChEBI A hydrazide consisting of hydrazine carrying one or more carboacyl groups. 0 CN2OR4 56.024 56.00106 N(C(*)=O)(N(*)*)* carbohydrazides chebi_ontology carbohydrazides CHEBI:35363 carbohydrazide CHEBI:35363 carbohydrazides IUPAC carbohydrazides ChEBI Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids. 0 CHO2R 45.01740 44.99765 OC([*])=O CHEBI:13633 CHEBI:24024 CHEBI:4984 KEGG:C00162 PMID:14287444 PMID:14300208 PMID:14328676 Wikipedia:Fatty_acid Fatty acid fatty acids chebi_ontology Fettsaeure Fettsaeuren acide gras acides gras acido graso acidos grasos fatty acids CHEBI:35366 fatty acid CHEBI:35366 PMID:14287444 Europe PMC PMID:14300208 Europe PMC PMID:14328676 Europe PMC Fatty acid KEGG_COMPOUND fatty acids IUPAC Fettsaeure ChEBI Fettsaeuren ChEBI acide gras ChEBI acides gras ChemIDplus acido graso ChEBI acidos grasos ChEBI fatty acids ChEBI Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group. CHEBI:25407 CHEBI:6984 KEGG:C06698 Monosaccharide monosaccharides chebi_ontology Monosaccharid Monosacharid monosacarido monosacaridos CHEBI:35381 monosaccharide CHEBI:35381 Monosaccharide KEGG_COMPOUND monosaccharides IUPAC Monosaccharid ChEBI Monosacharid ChEBI monosacarido ChEBI monosacaridos IUPAC An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen. CHEBI:33274 CHEBI:33436 oxoanion chebi_ontology oxoacid anions oxoanions CHEBI:35406 oxoanion CHEBI:35406 oxoanion ChEBI oxoacid anions ChEBI oxoanions ChEBI A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups. 0 H4N2R 32.045 32.03745 N[*]N CHEBI:26264 CHEBI:8408 KEGG:C02311 Primary diamine primary diamines chebi_ontology primary diamines CHEBI:35410 primary diamine CHEBI:35410 Primary diamine KEGG_COMPOUND primary diamines IUPAC primary diamines ChEBI A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H2NCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc. 0 (CH2)n.C2H8N2 H4N2(CH2)n CHEBI:10204 CHEBI:13775 CHEBI:13808 CHEBI:22316 CHEBI:2577 KEGG:C02896 KEGG:C03687 Alkane-alpha,omega-diamine chebi_ontology alkane-alpha,omega-diamines alpha,omega-Diamine CHEBI:35411 alkane-alpha,omega-diamine CHEBI:35411 Alkane-alpha,omega-diamine KEGG_COMPOUND alkane-alpha,omega-diamines ChEBI alpha,omega-Diamine KEGG_COMPOUND ortho-fused polycyclic hydrocarbon chebi_ontology ortho-fused polycyclic hydrocarbons CHEBI:35427 ortho-fused polycyclic hydrocarbon CHEBI:35427 ortho-fused polycyclic hydrocarbon ChEBI ortho-fused polycyclic hydrocarbons ChEBI Any glucoside in which the glycoside group is derived from D-glucose. 0 C6H11O6R 179.148 179.05556 [C@@H]1(OC([C@H](O)[C@H]([C@@H]1O)O)O*)CO CHEBI:21009 CHEBI:4173 KEGG:C01798 D-Glucoside chebi_ontology D-glucosides a D-glucoside CHEBI:35436 D-glucoside CHEBI:35436 D-Glucoside KEGG_COMPOUND D-glucosides ChEBI a D-glucoside UniProt A substance used in the prophylaxis or therapy of infectious diseases. chebi_ontology anti-infective agents anti-infective drugs antiinfective agents antiinfective drug CHEBI:35441 antiinfective agent CHEBI:35441 anti-infective agents ChEBI anti-infective drugs ChEBI antiinfective agents ChEBI antiinfective drug ChEBI A substance used to treat or prevent parasitic infections. Wikipedia:Antiparasitic chebi_ontology antiparasitic drugs antiparasitics parasiticides CHEBI:35442 antiparasitic agent CHEBI:35442 antiparasitic drugs ChEBI antiparasitics ChEBI parasiticides ChEBI Substance intended to kill parasitic worms (helminths). anthelminthic chebi_ontology anthelminthics anthelmintic anthelmintics antihelminth antihelmintico vermifuge CHEBI:35443 anthelminthic drug CHEBI:35443 anthelminthic IUPAC anthelminthics ChEBI anthelmintic IUPAC anthelmintics ChEBI antihelminth ChEBI antihelmintico ChEBI vermifuge ChEBI A substance used in the treatment or control of nematode infestations. chebi_ontology antinematodal agent antinematodal drugs antinematodals CHEBI:35444 antinematodal drug CHEBI:35444 antinematodal agent ChEBI antinematodal drugs ChEBI antinematodals ChEBI A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. chebi_ontology CNS agent CNS drugs central nervous system agents CHEBI:35470 central nervous system drug CHEBI:35470 CNS agent ChEBI CNS drugs ChEBI central nervous system agents ChEBI A substance that reduces or suppresses inflammation. chebi_ontology anti-inflammatory drugs antiinflammatory agent antiinflammatory drug antiinflammatory drugs CHEBI:35472 anti-inflammatory drug CHEBI:35472 anti-inflammatory drugs ChEBI antiinflammatory agent ChEBI antiinflammatory drug ChEBI antiinflammatory drugs ChEBI An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Wikipedia:Non-steroidal_anti-inflammatory_drug chebi_ontology NSAID NSAIDs non-steroidal anti-inflammatory agent non-steroidal anti-inflammatory drugs CHEBI:35475 non-steroidal anti-inflammatory drug CHEBI:35475 NSAID ChEBI NSAIDs ChEBI non-steroidal anti-inflammatory agent ChEBI non-steroidal anti-inflammatory drugs ChEBI chebi_ontology alkali metal salts CHEBI:35479 alkali metal salt CHEBI:35479 alkali metal salts ChEBI A loosely defined group of drugs that tend to reduce the activity of the central nervous system. chebi_ontology CNS depressants central nervous system depressants CHEBI:35488 central nervous system depressant CHEBI:35488 CNS depressants ChEBI central nervous system depressants ChEBI Compounds of structure RSSR in which R and R' are organic groups. 0 S2R2 64.13000 63.94414 [*]SS[*] disulfides chebi_ontology an organic disulfide organic disulfides CHEBI:35489 organic disulfide CHEBI:35489 disulfides IUPAC an organic disulfide UniProt organic disulfides ChEBI Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group. chebi_ontology CHEBI:35496 fluorobenzenes CHEBI:35496 A compound which inhibits or antagonises the biosynthesis or actions of androgens. Wikipedia:Antiandrogen chebi_ontology antiandrogen CHEBI:35497 androgen antagonist CHEBI:35497 antiandrogen ChEBI An agent that promotes the excretion of urine through its effects on kidney function. chebi_ontology diuretics CHEBI:35498 diuretic CHEBI:35498 diuretics ChEBI natural product fundamental parents chebi_ontology CHEBI:35507 natural product fundamental parent CHEBI:35507 natural product fundamental parents IUPAC chebi_ontology steroid fundamental parents CHEBI:35508 steroid fundamental parent CHEBI:35508 steroid fundamental parents ChEBI The 5alpha-stereoisomer of cholestane. 0 C27H48 InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1 XIIAYQZJNBULGD-XWLABEFZSA-N 372.67002 372.37560 [H][C@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCCC(C)C CHEBI:20650 Beilstein:2051806 CAS:481-21-0 HMDB:HMDB0041632 Reaxys:2051806 5alpha-cholestane chebi_ontology (5alpha)-cholestane alpha-cholestane CHEBI:35515 5alpha-cholestane CHEBI:35515 Beilstein:2051806 Beilstein CAS:481-21-0 ChemIDplus CAS:481-21-0 NIST Chemistry WebBook Reaxys:2051806 Reaxys 5alpha-cholestane IUPAC (5alpha)-cholestane NIST_Chemistry_WebBook alpha-cholestane NIST_Chemistry_WebBook 0 C27H48 InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21?,22+,23-,24+,25+,26+,27-/m1/s1 XIIAYQZJNBULGD-LDHZKLTISA-N 372.67002 372.37560 [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C Beilstein:5334741 CAS:14982-53-7 LIPID_MAPS_instance:LMST01010000 Wikipedia:Cholestane cholestane chebi_ontology CHEBI:35516 cholestane CHEBI:35516 Beilstein:5334741 Beilstein CAS:14982-53-7 ChemIDplus CAS:14982-53-7 NIST Chemistry WebBook LIPID_MAPS_instance:LMST01010000 LIPID MAPS cholestane IUPAC A drug which lowers the blood glucose level. chebi_ontology anti-hyperglycemic agent anti-hyperglycemic agents antidiabetic antihyperglycemic antihyperglycemic agent antihyperglycemic agents antihyperglycemic drug antihyperglycemic drugs antihyperglycemics hypoglycemic agents hypoglycemic drug hypoglycemic drugs CHEBI:35526 hypoglycemic agent CHEBI:35526 anti-hyperglycemic agent ChEBI anti-hyperglycemic agents ChEBI antidiabetic ChEBI antihyperglycemic ChEBI antihyperglycemic agent ChEBI antihyperglycemic agents ChEBI antihyperglycemic drug ChEBI antihyperglycemic drugs ChEBI antihyperglycemics ChEBI hypoglycemic agents ChEBI hypoglycemic drug ChEBI hypoglycemic drugs ChEBI 0 C2H3N3 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) NSPMIYGKQJPBQR-UHFFFAOYSA-N 69.06544 69.03270 c1nc[nH]n1 Beilstein:104767 CAS:288-88-0 Gmelin:122679 1H-1,2,4-triazole chebi_ontology s-Triazole CHEBI:35550 1H-1,2,4-triazole CHEBI:35550 Beilstein:104767 Beilstein CAS:288-88-0 NIST Chemistry WebBook Gmelin:122679 Gmelin 1H-1,2,4-triazole IUPAC s-Triazole NIST_Chemistry_WebBook heterocyclic parent hydrides chebi_ontology heterocyclic fundamental parent heterocyclic organic fundamental parents organic heterocyclic fundamental parents CHEBI:35552 heterocyclic organic fundamental parent CHEBI:35552 heterocyclic parent hydrides IUPAC heterocyclic fundamental parent ChEBI heterocyclic organic fundamental parents ChEBI organic heterocyclic fundamental parents ChEBI A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. chebi_ontology cardiovascular agent cardiovascular drugs CHEBI:35554 cardiovascular drug CHEBI:35554 cardiovascular agent ChEBI cardiovascular drugs ChEBI chebi_ontology mancude organic heteromonocyclic parents mancude-ring organic heteromonocyclic parents CHEBI:35555 mancude organic heteromonocyclic parent CHEBI:35555 mancude organic heteromonocyclic parents ChEBI mancude-ring organic heteromonocyclic parents ChEBI 0 C2H3N3 69.065 69.03270 DrugBank:DB03594 1,2,4-triazole chebi_ontology CHEBI:35560 1,2,4-triazole CHEBI:35560 1,2,4-triazole IUPAC 0 C2H3N3 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1H,2H2 FFGRBWANQMLTQI-UHFFFAOYSA-N 69.06544 69.03270 C1N=CN=N1 Beilstein:506536 Gmelin:362238 3H-1,2,4-triazole chebi_ontology CHEBI:35561 3H-1,2,4-triazole CHEBI:35561 Beilstein:506536 Beilstein Gmelin:362238 Gmelin 3H-1,2,4-triazole IUPAC Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds. mancude-ring systems chebi_ontology mancude rings mancunide-ring systems CHEBI:35568 mancude ring CHEBI:35568 mancude-ring systems IUPAC mancude rings ChEBI mancunide-ring systems IUPAC chebi_ontology mancude organic heterobicyclic parents mancude-ring organic heterobicyclic parents CHEBI:35570 mancude organic heterobicyclic parent CHEBI:35570 mancude organic heterobicyclic parents ChEBI mancude-ring organic heterobicyclic parents ChEBI chebi_ontology mancude organic heterocyclic parents mancude-ring organic heterocyclic parents CHEBI:35571 mancude organic heterocyclic parent CHEBI:35571 mancude organic heterocyclic parents ChEBI mancude-ring organic heterocyclic parents ChEBI chebi_ontology organic mancude parents organic mancude-ring parents CHEBI:35573 organic mancude parent CHEBI:35573 organic mancude parents ChEBI organic mancude-ring parents ChEBI A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n. carbon oxoanion chebi_ontology carbon oxoanions oxocarbon anion oxocarbon anions CHEBI:35604 carbon oxoanion CHEBI:35604 carbon oxoanion ChEBI carbon oxoanions ChEBI oxocarbon anion ChEBI oxocarbon anions ChEBI chebi_ontology carbon oxoacids oxoacids of carbon CHEBI:35605 carbon oxoacid CHEBI:35605 carbon oxoacids ChEBI oxoacids of carbon ChEBI A substance that inhibits or prevents the proliferation of neoplasms. chebi_ontology anticancer agent anticancer agents antineoplastic antineoplastic agents cytostatic CHEBI:35610 antineoplastic agent CHEBI:35610 anticancer agent ChEBI anticancer agents ChEBI antineoplastic ChEBI antineoplastic agents ChEBI cytostatic ChEBI Any ether in which the oxygen is attached to at least one aryl substituent. chebi_ontology CHEBI:35618 aromatic ether CHEBI:35618 A drug used to cause dilation of the blood vessels. chebi_ontology vasodilator vasodilator agents CHEBI:35620 vasodilator agent CHEBI:35620 vasodilator ChEBI vasodilator agents ChEBI chebi_ontology thiazolidine CHEBI:35622 thiazolidines CHEBI:35622 thiazolidine ChEBI A drug used to prevent seizures or reduce their severity. chebi_ontology Antiepileptika Antiepileptikum Antikonvulsiva Antikonvulsivum anti-convulsant anti-convulsants anti-convulsive agent anti-convulsive agents anticonvulsants anticonvulsive agent anticonvulsive agents antiepileptic antiepileptics antiepileptique antiepileptiques CHEBI:35623 anticonvulsant CHEBI:35623 Antiepileptika ChEBI Antiepileptikum ChEBI Antikonvulsiva ChEBI Antikonvulsivum ChEBI anti-convulsant ChEBI anti-convulsants ChEBI anti-convulsive agent ChEBI anti-convulsive agents ChEBI anticonvulsants ChEBI anticonvulsive agent ChEBI anticonvulsive agents ChEBI antiepileptic ChEBI antiepileptics ChEBI antiepileptique ChEBI antiepileptiques ChEBI An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6). chebi_ontology EC 3.5.2.6 (beta-lactamase) inhibitors EC 3.5.2.6 inhibitor EC 3.5.2.6 inhibitors ampicillinase inhibitor ampicillinase inhibitors beta-lactam hydrolase inhibitor beta-lactam hydrolase inhibitors beta-lactamase (EC 3.5.2.6) inhibitor beta-lactamase (EC 3.5.2.6) inhibitors beta-lactamase A, B, C inhibitor beta-lactamase A, B, C inhibitors beta-lactamase AME I inhibitor beta-lactamase AME I inhibitors beta-lactamase I-III inhibitor beta-lactamase I-III inhibitors beta-lactamase inhibitor beta-lactamase inhibitors cephalosporin-beta-lactamase inhibitor cephalosporin-beta-lactamase inhibitors cephalosporinase inhibitor cephalosporinase inhibitors exopenicillinase inhibitor exopenicillinase inhibitors neutrapen inhibitor neutrapen inhibitors penicillin amido-beta-lactamhydrolase inhibitor penicillin amido-beta-lactamhydrolase inhibitors penicillin beta-lactamase inhibitor penicillin beta-lactamase inhibitors penicillinase I, II inhibitor penicillinase I, II inhibitors penicillinase inhibitor penicillinase inhibitors CHEBI:35625 EC 3.5.2.6 (beta-lactamase) inhibitor CHEBI:35625 EC 3.5.2.6 (beta-lactamase) inhibitors ChEBI EC 3.5.2.6 inhibitor ChEBI EC 3.5.2.6 inhibitors ChEBI ampicillinase inhibitor ChEBI ampicillinase inhibitors ChEBI beta-lactam hydrolase inhibitor ChEBI beta-lactam hydrolase inhibitors ChEBI beta-lactamase (EC 3.5.2.6) inhibitor ChEBI beta-lactamase (EC 3.5.2.6) inhibitors ChEBI beta-lactamase A, B, C inhibitor ChEBI beta-lactamase A, B, C inhibitors ChEBI beta-lactamase AME I inhibitor ChEBI beta-lactamase AME I inhibitors ChEBI beta-lactamase I-III inhibitor ChEBI beta-lactamase I-III inhibitors ChEBI beta-lactamase inhibitor ChEBI beta-lactamase inhibitors ChEBI cephalosporin-beta-lactamase inhibitor ChEBI cephalosporin-beta-lactamase inhibitors ChEBI cephalosporinase inhibitor ChEBI cephalosporinase inhibitors ChEBI exopenicillinase inhibitor ChEBI exopenicillinase inhibitors ChEBI neutrapen inhibitor ChEBI neutrapen inhibitors ChEBI penicillin amido-beta-lactamhydrolase inhibitor ChEBI penicillin amido-beta-lactamhydrolase inhibitors ChEBI penicillin beta-lactamase inhibitor ChEBI penicillin beta-lactamase inhibitors ChEBI penicillinase I, II inhibitor ChEBI penicillinase I, II inhibitors ChEBI penicillinase inhibitor ChEBI penicillinase inhibitors ChEBI A lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon. 0 C3H2NOR3 68.054 68.01364 C1(C(N(*)C1*)=O)* CHEBI:10426 CHEBI:13203 CHEBI:22845 KEGG:C01866 Wikipedia:Beta-lactam beta-Lactam chebi_ontology a beta-lactam beta-lactams CHEBI:35627 beta-lactam CHEBI:35627 beta-Lactam KEGG_COMPOUND a beta-lactam UniProt beta-lactams ChEBI Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. Wikipedia:Antihypertensive_drug chebi_ontology antihypertensive antihypertensive agents antihypertensive drug antihypertensive drugs CHEBI:35674 antihypertensive agent CHEBI:35674 antihypertensive ChEBI antihypertensive agents ChEBI antihypertensive drug ChEBI antihypertensive drugs ChEBI A substance used to treat hyperlipidemia (an excess of lipids in the blood). Wikipedia:Hypolipidemic_agent chebi_ontology antihyperlipemic antihyperlipemics antihyperlipidaemic agent antihyperlipidaemic agents antihyperlipidaemic drug antihyperlipidaemic drugs antihyperlipidemic antihyperlipidemic agent antihyperlipidemic agents antihyperlipidemic drug antihyperlipidemic drugs antihyperlipidemics antilipemic antilipemic drugs antilipemics hypolipidemic agent hypolipidemic agents lipid-lowering agent lipid-lowering agents lipid-lowering drug lipid-lowering drugs CHEBI:35679 antilipemic drug CHEBI:35679 antihyperlipemic ChEBI antihyperlipemics ChEBI antihyperlipidaemic agent ChEBI antihyperlipidaemic agents ChEBI antihyperlipidaemic drug ChEBI antihyperlipidaemic drugs ChEBI antihyperlipidemic ChEBI antihyperlipidemic agent ChEBI antihyperlipidemic agents ChEBI antihyperlipidemic drug ChEBI antihyperlipidemic drugs ChEBI antihyperlipidemics ChEBI antilipemic ChEBI antilipemic drugs ChEBI antilipemics ChEBI hypolipidemic agent ChEBI hypolipidemic agents ChEBI lipid-lowering agent ChEBI lipid-lowering agents ChEBI lipid-lowering drug ChEBI lipid-lowering drugs ChEBI A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it. 0 CH2OR2 30.026 30.01056 *C(*)O CHEBI:13425 CHEBI:13686 CHEBI:26617 CHEBI:58662 CHEBI:8741 CHEBI:9077 KEGG:C00432 KEGG:C01612 Secondary alcohol chebi_ontology R-CHOH-R' a secondary alcohol secondary alcohols CHEBI:35681 secondary alcohol CHEBI:35681 Secondary alcohol KEGG_COMPOUND R-CHOH-R' KEGG_COMPOUND a secondary alcohol UniProt secondary alcohols ChEBI An azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom. chebi_ontology CHEBI:35689 tetrazoles CHEBI:35689 Any carboxylic acid containing two carboxy groups. CHEBI:23692 CHEBI:36172 CHEBI:4501 KEGG:C02028 Dicarboxylic acid chebi_ontology dicarboxylic acids CHEBI:35692 dicarboxylic acid CHEBI:35692 Dicarboxylic acid KEGG_COMPOUND dicarboxylic acids ChEBI dicarboxylic acid anion chebi_ontology dicarboxylic acid anions CHEBI:35693 dicarboxylic acid anion CHEBI:35693 dicarboxylic acid anion ChEBI dicarboxylic acid anions ChEBI Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid. chebi_ontology dicarboxylic acid monoanions CHEBI:35695 dicarboxylic acid monoanion CHEBI:35695 dicarboxylic acid monoanions ChEBI A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. CHEBI:23960 CHEBI:4859 KEGG:C00287 Wikipedia:Ester Ester chebi_ontology esters CHEBI:35701 ester CHEBI:35701 Ester KEGG_COMPOUND esters ChEBI A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. CHEBI:10074 CHEBI:27333 KEGG:C06708 Wikipedia:Xenobiotic Xenobiotic xenobiotic xenobiotics chebi_ontology xenobiotic compounds CHEBI:35703 xenobiotic CHEBI:35703 Xenobiotic KEGG_COMPOUND xenobiotic IUPAC xenobiotics IUPAC xenobiotic compounds ChEBI An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. chebi_ontology immunosuppressant immunosuppressive agents inmunosupresor CHEBI:35705 immunosuppressive agent CHEBI:35705 immunosuppressant ChEBI immunosuppressive agents ChEBI inmunosupresor ChEBI A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied). nitro compounds chebi_ontology CHEBI:35715 nitro compound CHEBI:35715 nitro compounds IUPAC A nitro compound having the nitro group (-NO2) attached to a carbon atom. C-nitro compounds chebi_ontology CHEBI:35716 C-nitro compound CHEBI:35716 C-nitro compounds IUPAC An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. chebi_ontology antifungal antifungal agents antifungal drug antifungal drugs antifungals CHEBI:35718 antifungal agent CHEBI:35718 antifungal ChEBI antifungal agents ChEBI antifungal drug ChEBI antifungal drugs ChEBI antifungals ChEBI A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid substituted by an oxo group at position 4, a fluoro group at position 6, a cyclopropyl group at position 1 and a 4-ethylpiperazin-1-yl group at position 7. It is a veterinary antibacterial agent used for the treatment of pets. 0 C19H22FN3O3 InChI=1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26) SPFYMRJSYKOXGV-UHFFFAOYSA-N 359.395 359.16452 C1=C(C(=CC2=C1N(C=C(C2=O)C(=O)O)C3CC3)F)N4CCN(CC4)CC CAS:93106-60-6 Drug_Central:1017 HMDB:HMDB0029861 KEGG:D02473 LINCS:LSM-3709 PMID:15967281 PMID:19376344 PMID:24380725 PMID:26963935 PMID:8828132 Patent:KR20130080422 Patent:RU2491922 Patent:US4659603 Reaxys:5307824 VSDB:1762 Wikipedia:Enrofloxacin 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Enrofloxacin chebi_ontology Baytril CHEBI:35720 enrofloxacin CHEBI:35720 CAS:93106-60-6 ChemIDplus Drug_Central:1017 DrugCentral PMID:15967281 Europe PMC PMID:19376344 Europe PMC PMID:24380725 Europe PMC PMID:26963935 Europe PMC PMID:8828132 Europe PMC Reaxys:5307824 Reaxys 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid IUPAC Enrofloxacin ChemIDplus Baytril ChemIDplus An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms. chebi_ontology triazole compounds CHEBI:35727 triazoles CHEBI:35727 triazole compounds ChEBI A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated. -1 CO2R 44.01000 43.98983 [O-]C([*])=O CHEBI:13657 CHEBI:25382 CHEBI:3407 KEGG:C00060 chebi_ontology Carboxylate Monocarboxylate a monocarboxylate monocarboxylates monocarboxylic acid anions CHEBI:35757 monocarboxylic acid anion CHEBI:35757 Carboxylate KEGG_COMPOUND Monocarboxylate KEGG_COMPOUND a monocarboxylate UniProt monocarboxylates ChEBI monocarboxylic acid anions ChEBI A phosphorus oxoanion that is the conjugate base of phosphoric acid. chebi_ontology Pi phosphate phosphate ions CHEBI:35780 phosphate ion CHEBI:35780 Pi ChEBI phosphate ChEBI phosphate ions ChEBI Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds. LIPID_MAPS_class:LMSP01 sphingoid chebi_ontology Spd sphingoid base sphingoid bases sphingoids CHEBI:35785 sphingoid CHEBI:35785 LIPID_MAPS_class:LMSP01 LIPID MAPS sphingoid CBN Spd CBN sphingoid base CBN sphingoid bases LIPID_MAPS sphingoids ChEBI An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom. oxazole chebi_ontology oxazoles CHEBI:35790 oxazole CHEBI:35790 oxazole ChEBI oxazoles ChEBI A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. chebi_ontology leprostatic leprostatic agent leprostatic drugs CHEBI:35816 leprostatic drug CHEBI:35816 leprostatic ChEBI leprostatic agent ChEBI leprostatic drugs ChEBI Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids. CHEBI:22919 CHEBI:3166 KEGG:C05996 PMID:18318842 chebi_ontology BCFA BCFAs Branched chain fatty acid branched fatty acid branched fatty acids branched-chain fatty acids CHEBI:35819 branched-chain fatty acid CHEBI:35819 PMID:18318842 Europe PMC BCFA ChEBI BCFAs ChEBI Branched chain fatty acid KEGG_COMPOUND branched fatty acid ChEBI branched fatty acids ChEBI branched-chain fatty acids ChEBI Any antimicrobial drug which is used to treat or prevent protozoal infections. Wikipedia:Antiprotozoal_agent chebi_ontology antiprotozoal agent antiprotozoal agents antiprotozoal drugs CHEBI:35820 antiprotozoal drug CHEBI:35820 antiprotozoal agent ChEBI antiprotozoal agents ChEBI antiprotozoal drugs ChEBI A drug used to treat rheumatoid arthritis. chebi_ontology anti-rheumatic drugs antirheumatic agent antirheumatic drugs CHEBI:35842 antirheumatic drug CHEBI:35842 anti-rheumatic drugs ChEBI antirheumatic agent ChEBI antirheumatic drugs ChEBI An organosulfur compound having the structure RS(=O)2R (R =/= H). sulfone chebi_ontology sulfones CHEBI:35850 sulfone CHEBI:35850 sulfone ChEBI sulfones ChEBI A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. chebi_ontology lipooxygenase inhibitor lipoxygenase inhibitors CHEBI:35856 lipoxygenase inhibitor CHEBI:35856 lipooxygenase inhibitor ChEBI lipoxygenase inhibitors ChEBI A homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. 0 C66H103N17O16S InChI=1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35-,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48-,52-,53-,54-/m0/s1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 1422.69300 1421.74894 CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC CAS:22601-59-8 KEGG:C15482 Reaxys:8969478 N-({(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl}carbonyl)-L-leucyl-D-alpha-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]-L-isoleucinamide chebi_ontology Bacitracin A2a Bacitracin F, 1-(N-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-l-leucine)- CHEBI:35862 bacitracin A CHEBI:35862 CAS:22601-59-8 ChemIDplus CAS:22601-59-8 KEGG COMPOUND Reaxys:8969478 Reaxys N-({(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl}carbonyl)-L-leucyl-D-alpha-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]-L-isoleucinamide IUPAC Bacitracin A2a ChemIDplus Bacitracin F, 1-(N-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-l-leucine)- ChemIDplus Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent. chebi_ontology hydroxy acid hydroxy monocarboxylic acids CHEBI:35868 hydroxy monocarboxylic acid CHEBI:35868 hydroxy acid ChEBI hydroxy monocarboxylic acids ChEBI Any monocarboxylic acid having at least one additional oxo functional group. chebi_ontology oxo monocarboxylic acids CHEBI:35871 oxo monocarboxylic acid CHEBI:35871 oxo monocarboxylic acids ChEBI chebi_ontology imidazopyrimidines CHEBI:35875 imidazopyrimidine CHEBI:35875 imidazopyrimidines ChEBI pnictogen hydride chebi_ontology pnictogen hydrides CHEBI:35881 pnictogen hydride CHEBI:35881 pnictogen hydride ChEBI pnictogen hydrides ChEBI CHEBI:35178 CHEBI:35901 chebi_ontology oxo monocarboxylic acid anions CHEBI:35902 oxo monocarboxylic acid anion CHEBI:35902 oxo monocarboxylic acid anions ChEBI Any carboxylic acid anion containing at least one oxo group. chebi_ontology oxo carboxylic acid anions CHEBI:35903 oxo carboxylic acid anion CHEBI:35903 oxo carboxylic acid anions ChEBI A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol. 0 C20H30O2R2 302.452 302.22458 C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCC(C4)OC(*)=O)C CHEBI:13220 CHEBI:15115 CHEBI:26770 CHEBI:26772 CHEBI:9268 CHEBI:9269 KEGG:C01958 Sterol ester chebi_ontology 3-hydroxysteroid ester 3-hydroxysteroid esters Steryl ester a sterol ester CHEBI:35915 sterol ester CHEBI:35915 Sterol ester KEGG_COMPOUND 3-hydroxysteroid ester ChEBI 3-hydroxysteroid esters ChEBI Steryl ester KEGG_COMPOUND a sterol ester UniProt A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. chebi_ontology neurotransmitter agents CHEBI:35942 neurotransmitter agent CHEBI:35942 neurotransmitter agents ChEBI An oxo monocarboxylic acid anion having the oxo group located at the 3-position (R = H or organyl group). -1 C3H2O3R 86.046 86.00039 C(C([O-])=O)C(*)=O chebi_ontology 3-oxo monocarboxylic acid anions a 3-oxo acid CHEBI:35973 3-oxo monocarboxylic acid anion CHEBI:35973 3-oxo monocarboxylic acid anions ChEBI a 3-oxo acid UniProt chebi_ontology 7-oxo monocarboxylic acids CHEBI:35983 7-oxo monocarboxylic acid CHEBI:35983 7-oxo monocarboxylic acids ChEBI Natural and synthetic antibiotics containing the 4-thia-1-azabicyclo[3.2.0]heptan-7-one structure, generally assumed to have the 5R configuration unless otherwise specified. penams chebi_ontology CHEBI:35992 penams CHEBI:35992 penams IUPAC Any stilbenoid with at least one phenolic group. stilbenol chebi_ontology CHEBI:36027 stilbenol CHEBI:36027 stilbenol ChEBI A drug used to treat or prevent microbial infections. chebi_ontology antimicrobial drugs CHEBI:36043 antimicrobial drug CHEBI:36043 antimicrobial drugs ChEBI A drug used to treat or prevent bacterial infections. Wikipedia:Antibacterial chebi_ontology antibacterial drugs CHEBI:36047 antibacterial drug CHEBI:36047 antibacterial drugs ChEBI Any monocarboxylic acid anion carrying at least one hydroxy substituent. chebi_ontology hydroxy monocarboxylic acid anions hydroxymonocarboxylic acid anion hydroxymonocarboxylic acid anions CHEBI:36059 hydroxy monocarboxylic acid anion CHEBI:36059 hydroxy monocarboxylic acid anions ChEBI hydroxymonocarboxylic acid anion ChEBI hydroxymonocarboxylic acid anions ChEBI A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. CHEBI:13677 CHEBI:14911 proteins chebi_ontology CHEBI:36080 protein CHEBI:36080 proteins IUPAC chebi_ontology inorganic chloride salt inorganic chloride salts inorganic chlorides CHEBI:36093 inorganic chloride CHEBI:36093 inorganic chloride salt ChEBI inorganic chloride salts ChEBI inorganic chlorides ChEBI Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included). CHEBI:13684 CHEBI:26517 Wikipedia:Quinone quinone quinones chebi_ontology Chinon quinones CHEBI:36141 quinone CHEBI:36141 quinone IUPAC quinones IUPAC Chinon ChEBI quinones ChEBI A compound in which two monosaccharides are joined by a glycosidic bond. CHEBI:23844 CHEBI:4654 KEGG:C01911 Disaccharide disaccharides chebi_ontology Disaccharid Disacharid disacarido disacaridos CHEBI:36233 disaccharide CHEBI:36233 Disaccharide KEGG_COMPOUND disaccharides IUPAC Disaccharid ChEBI Disacharid ChEBI disacarido ChEBI disacaridos IUPAC A monoester of a dicarboxylic acid. chebi_ontology dicarboxylic acid monoesters CHEBI:36244 dicarboxylic acid monoester CHEBI:36244 dicarboxylic acid monoesters ChEBI A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. chebi_ontology antitrypanosomal agent antitrypanosomal agents antitrypanosomal drug antitrypanosomal drugs trypanocidal drugs trypanocide trypanosomicidal agents CHEBI:36335 trypanocidal drug CHEBI:36335 antitrypanosomal agent ChEBI antitrypanosomal agents ChEBI antitrypanosomal drug ChEBI antitrypanosomal drugs ChEBI trypanocidal drugs ChEBI trypanocide ChEBI trypanosomicidal agents ChEBI chebi_ontology naphthalenesulfonic acids CHEBI:36336 naphthalenesulfonic acid CHEBI:36336 naphthalenesulfonic acids ChEBI Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin). chebi_ontology leptons CHEBI:36338 lepton CHEBI:36338 leptons ChEBI Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy). chebi_ontology baryons CHEBI:36339 baryon CHEBI:36339 baryons ChEBI Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. fermion chebi_ontology fermions CHEBI:36340 fermion CHEBI:36340 fermion IUPAC fermions ChEBI A particle smaller than an atom. Wikipedia:Subatomic_particle chebi_ontology subatomic particles CHEBI:36342 subatomic particle CHEBI:36342 subatomic particles ChEBI A subatomic particle known to have substructure (i.e. consisting of smaller particles). chebi_ontology composite particles CHEBI:36343 composite particle CHEBI:36343 composite particles ChEBI Hadron is a subatomic particle which experiences the strong force. chebi_ontology hadrons CHEBI:36344 hadron CHEBI:36344 hadrons ChEBI A nucleus or any of its constituents in any of their energy states. nuclear particle chebi_ontology CHEBI:36347 nuclear particle CHEBI:36347 nuclear particle IUPAC Any molecular entity consisting of more than one atom. chebi_ontology polyatomic entities CHEBI:36357 polyatomic entity CHEBI:36357 polyatomic entities ChEBI An ion consisting of more than one atom. chebi_ontology polyatomic ions CHEBI:36358 polyatomic ion CHEBI:36358 polyatomic ions ChEBI phosphorus oxoacid derivative chebi_ontology CHEBI:36359 phosphorus oxoacid derivative CHEBI:36359 phosphorus oxoacid derivative ChEBI chebi_ontology CHEBI:36360 phosphorus oxoacids and derivatives CHEBI:36360 0 H3O3P InChI=1S/H3O3P/c1-4(2)3/h1-3H OJMIONKXNSYLSR-UHFFFAOYSA-N 81.99578 81.98198 [H]OP(O[H])O[H] CHEBI:26081 CHEBI:29196 CAS:10294-56-1 Gmelin:164068 phosphorous acid trihydrogen trioxophosphate(3-) trihydroxidophosphorus trioxophosphoric(3-) acid chebi_ontology H3PO3 P(OH)3 [P(OH)3] phosphite phosphorige Saeure CHEBI:36361 phosphorous acid CHEBI:36361 CAS:10294-56-1 ChemIDplus CAS:10294-56-1 NIST Chemistry WebBook Gmelin:164068 Gmelin phosphorous acid IUPAC trihydrogen trioxophosphate(3-) IUPAC trihydroxidophosphorus IUPAC trioxophosphoric(3-) acid IUPAC H3PO3 IUPAC H3PO3 NIST_Chemistry_WebBook P(OH)3 IUPAC [P(OH)3] IUPAC phosphite UniProt phosphorige Saeure ChEBI An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, Asparagopsis taxiformis. 0 C2H2Cl2O2 InChI=1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6) JXTHNDFMNIQAHM-UHFFFAOYSA-N 128.94148 127.94318 OC(=O)C(Cl)Cl CHEBI:23695 CHEBI:4502 CHEBI:49918 Beilstein:1098596 CAS:79-43-6 DrugBank:DB08809 Drug_Central:862 Gmelin:2477 KEGG:C11149 LINCS:LSM-5314 MetaCyc:CPD-9674 PDBeChem:TF4 PMID:24112699 Reaxys:1098596 Wikipedia:Dichloroacetic_acid dichloroacetic acid chebi_ontology 2,2-dichloroacetic acid DICHLORO-ACETIC ACID Dichloressigsaeure Dichloroacetate bichloracetic acid dichloracetic acid CHEBI:36386 dichloroacetic acid CHEBI:36386 Beilstein:1098596 ChemIDplus CAS:79-43-6 ChemIDplus CAS:79-43-6 KEGG COMPOUND CAS:79-43-6 NIST Chemistry WebBook Drug_Central:862 DrugCentral Gmelin:2477 Gmelin PMID:24112699 Europe PMC Reaxys:1098596 Reaxys dichloroacetic acid IUPAC 2,2-dichloroacetic acid ChemIDplus DICHLORO-ACETIC ACID PDBeChem Dichloressigsaeure ChEBI Dichloroacetate KEGG_COMPOUND bichloracetic acid NIST_Chemistry_WebBook dichloracetic acid NIST_Chemistry_WebBook chebi_ontology saturated heterocyclic parent hydride saturated heterocyclic parent hydrides saturated organic heterocyclic parents CHEBI:36388 saturated organic heterocyclic parent CHEBI:36388 saturated heterocyclic parent hydride ChEBI saturated heterocyclic parent hydrides ChEBI saturated organic heterocyclic parents ChEBI chebi_ontology saturated heteromonocyclic parent hydride saturated heteromonocyclic parent hydrides saturated organic heteromonocyclic parents CHEBI:36389 saturated organic heteromonocyclic parent CHEBI:36389 saturated heteromonocyclic parent hydride ChEBI saturated heteromonocyclic parent hydrides ChEBI saturated organic heteromonocyclic parents ChEBI A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops. 0 C8Cl4N2 InChI=1S/C8Cl4N2/c9-5-3(1-13)6(10)8(12)7(11)4(5)2-14 CRQQGFGUEAVUIL-UHFFFAOYSA-N 265.90988 263.88156 Clc1c(Cl)c(C#N)c(Cl)c(C#N)c1Cl Beilstein:1978326 CAS:1897-45-6 KEGG:C11037 PMID:11016668 PMID:14575671 PMID:17482661 PMID:23116300 PMID:23866729 PMID:24455968 PMID:24984836 PMID:24990551 PPDB:150 Patent:US3290353 Patent:US3652637 Pesticides:chlorothalonil Reaxys:1978326 Wikipedia:Chlorothalonil 2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile Chlorothalonil chlorothalonil chebi_ontology 1,3-Dicyanotetrachlorobenzene 2,4,5,6-Tetrachloro-3-cyanobenzonitrile Daconil TPN Tetrachloroisophthalonitrile m-TCPN m-Tetrachlorophthalonitrile meta-TCPN meta-Tetrachlorophthalodinitrile CHEBI:3639 chlorothalonil CHEBI:3639 Beilstein:1978326 Beilstein CAS:1897-45-6 KEGG COMPOUND CAS:1897-45-6 NIST Chemistry WebBook PMID:11016668 Europe PMC PMID:14575671 Europe PMC PMID:17482661 Europe PMC PMID:23116300 Europe PMC PMID:23866729 Europe PMC PMID:24455968 Europe PMC PMID:24984836 Europe PMC PMID:24990551 Europe PMC Pesticides:chlorothalonil Alan Wood's Pesticides Reaxys:1978326 Reaxys 2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile IUPAC Chlorothalonil KEGG_COMPOUND chlorothalonil UniProt 1,3-Dicyanotetrachlorobenzene ChemIDplus 2,4,5,6-Tetrachloro-3-cyanobenzonitrile ChemIDplus Daconil KEGG_COMPOUND TPN KEGG_COMPOUND Tetrachloroisophthalonitrile KEGG_COMPOUND m-TCPN ChemIDplus m-Tetrachlorophthalonitrile ChemIDplus meta-TCPN ChemIDplus meta-Tetrachlorophthalodinitrile ChemIDplus chebi_ontology zinc group coordination compounds zinc group coordination entities CHEBI:36563 zinc group coordination entity CHEBI:36563 zinc group coordination compounds ChEBI zinc group coordination entities ChEBI chebi_ontology zinc coordination compounds zinc coordination entities CHEBI:36566 zinc coordination entity CHEBI:36566 zinc coordination compounds ChEBI zinc coordination entities ChEBI Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. carbonyl compounds chebi_ontology CHEBI:36586 carbonyl compound CHEBI:36586 carbonyl compounds IUPAC Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. oxo compounds chebi_ontology organic oxo compounds CHEBI:36587 organic oxo compound CHEBI:36587 oxo compounds IUPAC organic oxo compounds ChEBI A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings. 0 C7H6N2 118.136 118.05310 Wikipedia:Benzimidazole benzimidazole chebi_ontology Benzimidazol CHEBI:36622 benzimidazole CHEBI:36622 benzimidazole IUPAC Benzimidazol ChEBI 0 C7H6N2 InChI=1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-3,5H,4H2 VSTRESXSGAUGKC-UHFFFAOYSA-N 118.13602 118.05310 C1C=CC=C2N=CN=C12 4H-benzimidazole chebi_ontology CHEBI:36623 4H-benzimidazole CHEBI:36623 4H-benzimidazole IUPAC Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class. 0 C8H6N2 130.147 130.05310 Wikipedia:Naphthyridine naphthyridine chebi_ontology CHEBI:36624 naphthyridine CHEBI:36624 naphthyridine IUPAC A naphthyridine in which the nitrogens are situated at positions 1 and 8. 0 C8H6N2 InChI=1S/C8H6N2/c1-3-7-4-2-6-10-8(7)9-5-1/h1-6H FLBAYUMRQUHISI-UHFFFAOYSA-N 130.14660 130.05310 c1cnc2ncccc2c1 Beilstein:109347 CAS:254-60-4 Gmelin:27124 Reaxys:109347 1,8-naphthyridine chebi_ontology 1,8-diazanaphthalene 1,8-pyridopyridine napy CHEBI:36628 1,8-naphthyridine CHEBI:36628 Beilstein:109347 Beilstein CAS:254-60-4 ChemIDplus CAS:254-60-4 NIST Chemistry WebBook Gmelin:27124 Gmelin Reaxys:109347 Reaxys 1,8-naphthyridine IUPAC 1,8-diazanaphthalene NIST_Chemistry_WebBook 1,8-pyridopyridine NIST_Chemistry_WebBook napy IUPAC 0 C7H6N2 InChI=1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-4H,5H2 NLMVLMCSXDIGSW-UHFFFAOYSA-N 118.13602 118.05310 C1N=c2ccccc2=N1 2H-benzimidazole chebi_ontology CHEBI:36639 2H-benzimidazole CHEBI:36639 2H-benzimidazole IUPAC 0 C7H6N2 InChI=1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-6H VRKAZVNMMPXRKG-UHFFFAOYSA-N 118.13602 118.05310 C1=CC2N=CN=C2C=C1 3aH-benzimidazole chebi_ontology CHEBI:36641 3aH-benzimidazole CHEBI:36641 3aH-benzimidazole IUPAC An organochlorine compound is a compound containing at least one carbon-chlorine bond. 0 ClR 35.453 34.96885 Cl[*] MetaCyc:Chlorides Wikipedia:Organochloride organochlorine compound chebi_ontology an organochlorine molecule chloroorganic compounds chlororganische Verbindungen organochloride organochloride compound organochloride compounds organochlorides organochlorine compounds CHEBI:36683 organochlorine compound CHEBI:36683 organochlorine compound ChEBI an organochlorine molecule UniProt chloroorganic compounds ChEBI chlororganische Verbindungen ChEBI organochloride ChEBI organochloride compound ChEBI organochloride compounds ChEBI organochlorides ChEBI organochlorine compounds ChEBI heterotricyclic compound heterotricyclic compounds chebi_ontology heterotricyclic compounds CHEBI:36688 heterotricyclic compound CHEBI:36688 heterotricyclic compound ChEBI heterotricyclic compounds IUPAC heterotricyclic compounds ChEBI Any compound having phosphocholine as part of its structure. chebi_ontology O-phosphocholines choline phosphates phosphorylcholines CHEBI:36700 phosphocholines CHEBI:36700 O-phosphocholines ChEBI choline phosphates ChEBI phosphorylcholines ChEBI Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups. aminoquinoline chebi_ontology aminoquinolines CHEBI:36709 aminoquinoline CHEBI:36709 aminoquinoline ChEBI aminoquinolines ChEBI A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10. 0 C15H32 InChI=1S/C15H32/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h13-15H,6-12H2,1-5H3 YFHFHLSMISYUAQ-UHFFFAOYSA-N 212.41458 212.25040 CCC(C)CCCC(C)CCCC(C)C Beilstein:1719672 CAS:3891-98-3 LIPID_MAPS_instance:LMPR0103010000 MetaCyc:CPD-8764 Patent:US2008098645 Patent:US7399323 Reaxys:1719672 2,6,10-trimethyldodecane farnesane chebi_ontology Farnesan CHEBI:36756 farnesane CHEBI:36756 Beilstein:1719672 Beilstein CAS:3891-98-3 ChemIDplus CAS:3891-98-3 NIST Chemistry WebBook LIPID_MAPS_instance:LMPR0103010000 LIPID MAPS Reaxys:1719672 Reaxys 2,6,10-trimethyldodecane IUPAC farnesane NIST_Chemistry_WebBook Farnesan NIST_Chemistry_WebBook farnesane sesquiterpenoid chebi_ontology farnesane sesquiterpenoids CHEBI:36757 farnesane sesquiterpenoid CHEBI:36757 farnesane sesquiterpenoid ChEBI farnesane sesquiterpenoids ChEBI A bicyclic compound in which all the ring atoms are carbon. chebi_ontology carbobicyclic compounds CHEBI:36785 carbobicyclic compound CHEBI:36785 carbobicyclic compounds ChEBI O-organyl oximes R2C=NOR' (R' =/= H). 0 CNOR3 42.017 41.99799 [*]O\N=C(/[*])[*] oxime O-ether oxime O-ethers chebi_ontology O-substituted oximes oxime O-ethers oxime ether oxime ethers CHEBI:36816 oxime O-ether CHEBI:36816 oxime O-ether IUPAC oxime O-ethers IUPAC O-substituted oximes ChEBI oxime O-ethers ChEBI oxime ether ChEBI oxime ethers ChEBI Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved. ring assemblies ring assembly chebi_ontology CHEBI:36820 ring assembly CHEBI:36820 ring assemblies IUPAC ring assembly IUPAC pseudohalide group chebi_ontology halogenoid group pseudohalido group pseudohalo groups pseudohalogen group CHEBI:36823 pseudohalo group CHEBI:36823 pseudohalide group IUPAC halogenoid group ChEBI pseudohalido group ChEBI pseudohalo groups ChEBI pseudohalogen group IUPAC pseudohalide ions chebi_ontology pseudohalide anions pseudohalides pseudohalogen anion pseudohalogen ion CHEBI:36828 pseudohalide anion CHEBI:36828 pseudohalide ions IUPAC pseudohalide anions ChEBI pseudohalides ChEBI pseudohalogen anion ChEBI pseudohalogen ion ChEBI chebi_ontology polyatomic monoanions CHEBI:36829 polyatomic monoanion CHEBI:36829 polyatomic monoanions ChEBI -1 chebi_ontology monoanions CHEBI:36830 monoanion CHEBI:36830 monoanions ChEBI Any hydroxy steroid carrying a hydroxy group at position 3. chebi_ontology 3-hydroxy steroids CHEBI:36834 3-hydroxy steroid CHEBI:36834 3-hydroxy steroids ChEBI A 3-hydroxy steroid in which the 3-hydroxy substituent is in the alpha-position. 0 C19H31OR 275.450 275.23749 C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CC[C@H](C4)O)C CHEBI:71194 MetaCyc:3-alpha-Hydroxysteroids PMID:11514561 chebi_ontology 3alpha-hydroxy steroids 3alpha-hydroxysteroid 3alpha-hydroxysteroids a 3alpha-hydroxysteroid CHEBI:36835 3alpha-hydroxy steroid CHEBI:36835 PMID:11514561 SUBMITTER 3alpha-hydroxy steroids ChEBI 3alpha-hydroxysteroid ChEBI 3alpha-hydroxysteroids ChEBI a 3alpha-hydroxysteroid UniProt chebi_ontology 11-hydroxy steroids CHEBI:36841 11-hydroxy steroid CHEBI:36841 11-hydroxy steroids ChEBI 0 CHN InChI=1S/CHN/c1-2/h2H QIUBLANJVAOHHY-UHFFFAOYSA-N 27.02538 27.01090 [C-]#[NH+] Beilstein:2069401 CAS:6914-07-4 Gmelin:113 hydrogen isocyanide nitriliomethanide chebi_ontology CNH HN(+)#C(-) HNC hydroisocyanic acid CHEBI:36856 hydrogen isocyanide CHEBI:36856 Beilstein:2069401 Beilstein CAS:6914-07-4 NIST Chemistry WebBook Gmelin:113 Gmelin hydrogen isocyanide NIST_Chemistry_WebBook nitriliomethanide IUPAC CNH ChEBI HN(+)#C(-) IUPAC HNC NIST_Chemistry_WebBook hydroisocyanic acid ChEBI chalcogen hydride chebi_ontology chalcogen hydrides CHEBI:36902 chalcogen hydride CHEBI:36902 chalcogen hydride ChEBI chalcogen hydrides ChEBI chebi_ontology inorganic ions CHEBI:36914 inorganic ion CHEBI:36914 inorganic ions ChEBI chebi_ontology inorganic cations CHEBI:36915 inorganic cation CHEBI:36915 inorganic cations ChEBI A monoatomic or polyatomic species having one or more elementary charges of the proton. CHEBI:23058 CHEBI:3473 KEGG:C01373 Cation cation chebi_ontology Kation Kationen cationes cations CHEBI:36916 cation CHEBI:36916 Cation KEGG_COMPOUND cation ChEBI cation IUPAC Kation ChEBI Kationen ChEBI cationes ChEBI cations ChEBI chalcocarbonic acid chalcocarbonic acids chebi_ontology chalcocarbonic acids CHEBI:36961 chalcocarbonic acid CHEBI:36961 chalcocarbonic acid ChEBI chalcocarbonic acids IUPAC chalcocarbonic acids ChEBI An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. organochalcogen compound chebi_ontology organochalcogen compounds CHEBI:36962 organochalcogen compound CHEBI:36962 organochalcogen compound ChEBI organochalcogen compounds ChEBI An organochalcogen compound containing at least one carbon-oxygen bond. PMID:17586126 organooxygen compound chebi_ontology organooxygen compounds CHEBI:36963 organooxygen compound CHEBI:36963 PMID:17586126 Europe PMC organooxygen compound ChEBI organooxygen compounds ChEBI A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid. CHEBI:13215 CHEBI:13663 CHEBI:7656 KEGG:C00215 Wikipedia:Nucleotide Nucleotide chebi_ontology nucleotides CHEBI:36976 nucleotide CHEBI:36976 Nucleotide KEGG_COMPOUND nucleotides ChEBI chebi_ontology cyclic purine nucleotides CHEBI:36982 cyclic purine nucleotide CHEBI:36982 cyclic purine nucleotides ChEBI chebi_ontology CHEBI:36988 5'-deoxyribonucleoside CHEBI:36988 amino-acid anion chebi_ontology amino acid anions amino-acid anions CHEBI:37022 amino-acid anion CHEBI:37022 amino-acid anion ChEBI amino acid anions ChEBI amino-acid anions ChEBI An organoiodine compound is a compound containing at least one carbon-iodine bond. 0 IR 126.904 126.90447 *I MetaCyc:Organoiodine-Compounds Wikipedia:Organoiodine_compound organoiodine compound chebi_ontology organoiodine compounds CHEBI:37142 organoiodine compound CHEBI:37142 organoiodine compound ChEBI organoiodine compounds ChEBI An organofluorine compound is a compound containing at least one carbon-fluorine bond. 0 FR 18.998 18.99840 *F MetaCyc:Fluorides organofluorine compound chebi_ontology fluoroorganic compound fluoroorganic compounds fluoroorganics fluororganische Verbindungen organofluorine compounds CHEBI:37143 organofluorine compound CHEBI:37143 organofluorine compound ChEBI fluoroorganic compound ChEBI fluoroorganic compounds ChEBI fluoroorganics ChEBI fluororganische Verbindungen ChEBI organofluorine compounds ChEBI Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16). CHEBI:62670 Wikipedia:Phosphoprotein_phosphatase Wikipedia:Protein_serine/threonine_phosphatase chebi_ontology 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors Aspergillus awamori acid protein phosphatase inhibitor Aspergillus awamori acid protein phosphatase inhibitors BCKDH phosphatase inhibitor BCKDH phosphatase inhibitors EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors EC 3.1.3.16 inhibitor EC 3.1.3.16 inhibitors HMG-CoA reductase phosphatase inhibitor HMG-CoA reductase phosphatase inhibitors branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors calcineurin inhibitor calcineurin inhibitors casein phosphatase inhibitor casein phosphatase inhibitors phosphatase 2A inhibitor phosphatase 2A inhibitors phosphatase 2B inhibitor phosphatase 2B inhibitors phosphatase C-II inhibitor phosphatase C-II inhibitors phosphatase H-II inhibitor phosphatase H-II inhibitors phosphatase I inhibitor phosphatase I inhibitors phosphatase IB inhibitor phosphatase IB inhibitors phosphatase II inhibitor phosphatase II inhibitors phosphatase III inhibitor phosphatase III inhibitors phosphatase IV inhibitor phosphatase IV inhibitors phosphatase SP inhibitor phosphatase SP inhibitors phosphoprotein phosphatase (EC 3.1.3.16) inhibitor phosphoprotein phosphatase (EC 3.1.3.16) inhibitors phosphoprotein phosphatase inhibitor phosphoprotein phosphatase inhibitors phosphoprotein phosphohydrolase inhibitor phosphoprotein phosphohydrolase inhibitors phosphopyruvate dehydrogenase phosphatase inhibitor phosphopyruvate dehydrogenase phosphatase inhibitors phosphospectrin phosphatase inhibitor phosphospectrin phosphatase inhibitors polycation modulated (PCM-) phosphatase inhibitor polycation modulated (PCM-) phosphatase inhibitors protein D phosphatase inhibitor protein D phosphatase inhibitors protein phosphatase inhibitor protein phosphatase inhibitors protein phosphatase-1 inhibitor protein phosphatase-1 inhibitors protein phosphatase-2A inhibitor protein phosphatase-2A inhibitors protein phosphatase-2B inhibitor protein phosphatase-2B inhibitors protein phosphatase-2C inhibitor protein phosphatase-2C inhibitors protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors protein serine/threonine phosphatase inhibitor protein serine/threonine phosphatase inhibitors serine/threonine specific protein phosphatase inhibitor serine/threonine specific protein phosphatase inhibitors CHEBI:37153 EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor CHEBI:37153 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor ChEBI 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors ChEBI Aspergillus awamori acid protein phosphatase inhibitor ChEBI Aspergillus awamori acid protein phosphatase inhibitors ChEBI BCKDH phosphatase inhibitor ChEBI BCKDH phosphatase inhibitors ChEBI EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors ChEBI EC 3.1.3.16 inhibitor ChEBI EC 3.1.3.16 inhibitors ChEBI HMG-CoA reductase phosphatase inhibitor ChEBI HMG-CoA reductase phosphatase inhibitors ChEBI branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor ChEBI branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors ChEBI calcineurin inhibitor ChEBI calcineurin inhibitors ChEBI casein phosphatase inhibitor ChEBI casein phosphatase inhibitors ChEBI phosphatase 2A inhibitor ChEBI phosphatase 2A inhibitors ChEBI phosphatase 2B inhibitor ChEBI phosphatase 2B inhibitors ChEBI phosphatase C-II inhibitor ChEBI phosphatase C-II inhibitors ChEBI phosphatase H-II inhibitor ChEBI phosphatase H-II inhibitors ChEBI phosphatase I inhibitor ChEBI phosphatase I inhibitors ChEBI phosphatase IB inhibitor ChEBI phosphatase IB inhibitors ChEBI phosphatase II inhibitor ChEBI phosphatase II inhibitors ChEBI phosphatase III inhibitor ChEBI phosphatase III inhibitors ChEBI phosphatase IV inhibitor ChEBI phosphatase IV inhibitors ChEBI phosphatase SP inhibitor ChEBI phosphatase SP inhibitors ChEBI phosphoprotein phosphatase (EC 3.1.3.16) inhibitor ChEBI phosphoprotein phosphatase (EC 3.1.3.16) inhibitors ChEBI phosphoprotein phosphatase inhibitor ChEBI phosphoprotein phosphatase inhibitors ChEBI phosphoprotein phosphohydrolase inhibitor ChEBI phosphoprotein phosphohydrolase inhibitors ChEBI phosphopyruvate dehydrogenase phosphatase inhibitor ChEBI phosphopyruvate dehydrogenase phosphatase inhibitors ChEBI phosphospectrin phosphatase inhibitor ChEBI phosphospectrin phosphatase inhibitors ChEBI polycation modulated (PCM-) phosphatase inhibitor ChEBI polycation modulated (PCM-) phosphatase inhibitors ChEBI protein D phosphatase inhibitor ChEBI protein D phosphatase inhibitors ChEBI protein phosphatase inhibitor ChEBI protein phosphatase inhibitors ChEBI protein phosphatase-1 inhibitor ChEBI protein phosphatase-1 inhibitors ChEBI protein phosphatase-2A inhibitor ChEBI protein phosphatase-2A inhibitors ChEBI protein phosphatase-2B inhibitor ChEBI protein phosphatase-2B inhibitors ChEBI protein phosphatase-2C inhibitor ChEBI protein phosphatase-2C inhibitors ChEBI protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors ChEBI protein serine/threonine phosphatase inhibitor ChEBI protein serine/threonine phosphatase inhibitors ChEBI serine/threonine specific protein phosphatase inhibitor ChEBI serine/threonine specific protein phosphatase inhibitors ChEBI chebi_ontology organic hydrides CHEBI:37175 organic hydride CHEBI:37175 organic hydrides ChEBI mononuclear parent hydrides chebi_ontology mononuclear hydride mononuclear hydrides CHEBI:37176 mononuclear parent hydride CHEBI:37176 mononuclear parent hydrides IUPAC mononuclear hydride ChEBI mononuclear hydrides IUPAC A polyol that contains 6 hydroxy groups. hexol chebi_ontology hexols CHEBI:37206 hexol CHEBI:37206 hexol IUPAC hexols ChEBI chebi_ontology CHEBI:37246 elemental sodium CHEBI:37246 chebi_ontology CHEBI:37247 elemental potassium CHEBI:37247 The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis. 0 C38H69NO13 InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 AGOYDEPGAOXOCK-KCBOHYOISA-N 747.95340 747.47689 [H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C)OC CHEBI:41676 CHEBI:442148 CHEBI:670147 Beilstein:3581974 CAS:81103-11-9 DrugBank:DB01211 Drug_Central:668 KEGG:C06912 KEGG:D00276 LINCS:LSM-5606 LIPID_MAPS_instance:LMPK04000014 PDBeChem:CTY PMID:16387493 Patent:EP41355 Patent:US4331803 Reaxys:3581974 CLARITHROMYCIN Clarithromycin O(6)-methylerythromycin chebi_ontology 6-O-methylerythromycin 6-O-methylerythromycin A CLA clarithromycin clarithromycina clarithromycine clarithromycinum CHEBI:3732 clarithromycin CHEBI:3732 Beilstein:3581974 Beilstein CAS:81103-11-9 ChemIDplus CAS:81103-11-9 KEGG COMPOUND Drug_Central:668 DrugCentral LIPID_MAPS_instance:LMPK04000014 LIPID MAPS PMID:16387493 ChEMBL Reaxys:3581974 Reaxys CLARITHROMYCIN PDBeChem Clarithromycin KEGG_COMPOUND O(6)-methylerythromycin IUPAC 6-O-methylerythromycin ChemIDplus 6-O-methylerythromycin A ChemIDplus CLA DrugBank clarithromycin ChemIDplus clarithromycina ChemIDplus clarithromycine ChemIDplus clarithromycinum ChemIDplus chebi_ontology CHEBI:37404 elemental copper CHEBI:37404 Any ether in which the oxygen atom forms part of a ring. CHEBI:37406 cyclic ether cyclic ethers epoxy compounds chebi_ontology cyclic ethers epoxy compounds CHEBI:37407 cyclic ether CHEBI:37407 cyclic ether IUPAC cyclic ethers IUPAC epoxy compounds IUPAC cyclic ethers ChEBI epoxy compounds ChEBI An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6). Wikipedia:RNA_polymerase chebi_ontology C RNA formation factors inhibitor C RNA formation factors inhibitors C ribonucleic acid formation factors inhibitor C ribonucleic acid formation factors inhibitors DNA-dependent RNA nucleotidyltransferase inhibitor DNA-dependent RNA nucleotidyltransferase inhibitors DNA-dependent RNA polymerase inhibitor DNA-dependent RNA polymerase inhibitors DNA-dependent ribonucleate nucleotidyltransferase inhibitor DNA-dependent ribonucleate nucleotidyltransferase inhibitors DNA-directed RNA polymerase inhibitor DNA-directed RNA polymerase inhibitors DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors EC 2.7.7.6 (RNA polymerase) inhibitors EC 2.7.7.6 inhibitor EC 2.7.7.6 inhibitors RNA nucleotidyltransferase (DNA-directed) inhibitor RNA nucleotidyltransferase (DNA-directed) inhibitors RNA nucleotidyltransferase inhibitor RNA nucleotidyltransferase inhibitors RNA polymerase (EC 2.7.7.6) inhibitor RNA polymerase (EC 2.7.7.6) inhibitors RNA polymerase I inhibitor RNA polymerase I inhibitors RNA polymerase II inhibitor RNA polymerase II inhibitors RNA polymerase III inhibitor RNA polymerase III inhibitors RNA polymerase inhibitor RNA polymerase inhibitors RNA transcriptase inhibitor RNA transcriptase inhibitors deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors directed RNA polymerase inhibitor nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors ribonucleate nucleotidyltransferase inhibitor ribonucleate nucleotidyltransferase inhibitors ribonucleate polymerase inhibitor ribonucleate polymerase inhibitors ribonucleic acid nucleotidyltransferase inhibitor ribonucleic acid nucleotidyltransferase inhibitors ribonucleic acid polymerase inhibitor ribonucleic acid polymerase inhibitors ribonucleic acid transcriptase inhibitor ribonucleic acid transcriptase inhibitors ribonucleic polymerase inhibitor ribonucleic polymerase inhibitors ribonucleic transcriptase inhibitor ribonucleic transcriptase inhibitors transcriptase inhibitor transcriptase inhibitors CHEBI:37416 EC 2.7.7.6 (RNA polymerase) inhibitor CHEBI:37416 C RNA formation factors inhibitor ChEBI C RNA formation factors inhibitors ChEBI C ribonucleic acid formation factors inhibitor ChEBI C ribonucleic acid formation factors inhibitors ChEBI DNA-dependent RNA nucleotidyltransferase inhibitor ChEBI DNA-dependent RNA nucleotidyltransferase inhibitors ChEBI DNA-dependent RNA polymerase inhibitor ChEBI DNA-dependent RNA polymerase inhibitors ChEBI DNA-dependent ribonucleate nucleotidyltransferase inhibitor ChEBI DNA-dependent ribonucleate nucleotidyltransferase inhibitors ChEBI DNA-directed RNA polymerase inhibitor ChEBI DNA-directed RNA polymerase inhibitors ChEBI DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor ChEBI DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors ChEBI EC 2.7.7.6 (RNA polymerase) inhibitors ChEBI EC 2.7.7.6 inhibitor ChEBI EC 2.7.7.6 inhibitors ChEBI RNA nucleotidyltransferase (DNA-directed) inhibitor ChEBI RNA nucleotidyltransferase (DNA-directed) inhibitors ChEBI RNA nucleotidyltransferase inhibitor ChEBI RNA nucleotidyltransferase inhibitors ChEBI RNA polymerase (EC 2.7.7.6) inhibitor ChEBI RNA polymerase (EC 2.7.7.6) inhibitors ChEBI RNA polymerase I inhibitor ChEBI RNA polymerase I inhibitors ChEBI RNA polymerase II inhibitor ChEBI RNA polymerase II inhibitors ChEBI RNA polymerase III inhibitor ChEBI RNA polymerase III inhibitors ChEBI RNA polymerase inhibitor ChEBI RNA polymerase inhibitors ChEBI RNA transcriptase inhibitor ChEBI RNA transcriptase inhibitors ChEBI deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor ChEBI deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors ChEBI directed RNA polymerase inhibitor ChEBI nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor ChEBI nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors ChEBI ribonucleate nucleotidyltransferase inhibitor ChEBI ribonucleate nucleotidyltransferase inhibitors ChEBI ribonucleate polymerase inhibitor ChEBI ribonucleate polymerase inhibitors ChEBI ribonucleic acid nucleotidyltransferase inhibitor ChEBI ribonucleic acid nucleotidyltransferase inhibitors ChEBI ribonucleic acid polymerase inhibitor ChEBI ribonucleic acid polymerase inhibitors ChEBI ribonucleic acid transcriptase inhibitor ChEBI ribonucleic acid transcriptase inhibitors ChEBI ribonucleic polymerase inhibitor ChEBI ribonucleic polymerase inhibitors ChEBI ribonucleic transcriptase inhibitor ChEBI ribonucleic transcriptase inhibitors ChEBI transcriptase inhibitor ChEBI transcriptase inhibitors ChEBI A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic. 0 C18H33ClN2O5S InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9?,10-,11+,12?,13+,14-,15-,16-,18-/m1/s1 KDLRVYVGXIQJDK-NOWPCOIGSA-N 424.98380 424.17987 CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O CHEBI:47331 CAS:18323-44-9 DrugBank:DB01190 HMDB:HMDB0015321 KEGG:C06914 KEGG:C13684 KEGG:D00277 KEGG:D02132 PMID:11691576 PMID:18695329 PMID:24310902 Reaxys:5624049 Wikipedia:Clindamycin Clindamycin methyl 7-chloro-6,7,8-trideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-glycero-alpha-D-galacto-octopyranoside chebi_ontology 7(S)-Chloro-7-deoxylincomycin 7-CDL Cleocin (TN) Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside CHEBI:3745 clindamycin CHEBI:3745 CAS:18323-44-9 ChemIDplus CAS:18323-44-9 KEGG COMPOUND PMID:11691576 Europe PMC PMID:18695329 Europe PMC PMID:24310902 Europe PMC Reaxys:5624049 Reaxys Clindamycin KEGG_COMPOUND methyl 7-chloro-6,7,8-trideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-glycero-alpha-D-galacto-octopyranoside IUPAC 7(S)-Chloro-7-deoxylincomycin ChemIDplus 7-CDL ChemIDplus Cleocin (TN) KEGG_DRUG Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside ChemIDplus 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. 0 C27H22Cl2N4 InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3 WDQPAMHFFCXSNU-UHFFFAOYSA-N 473.39600 472.12215 CC(C)N=c1cc2n(-c3ccc(Cl)cc3)c3ccccc3nc2cc1Nc1ccc(Cl)cc1 CHEBI:355347 Beilstein:8168151 CAS:2030-63-9 DrugBank:DB00845 KEGG:C06915 KEGG:D00278 LINCS:LSM-5669 PMID:17210775 PMID:3279207 Patent:US2948726 N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine chebi_ontology (4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine 3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine 3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine clofazimina clofazimine clofaziminum CHEBI:3749 clofazimine CHEBI:3749 Beilstein:8168151 Beilstein CAS:2030-63-9 ChemIDplus CAS:2030-63-9 KEGG COMPOUND PMID:17210775 ChEMBL PMID:3279207 ChEMBL N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine IUPAC (4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine ChEMBL 3-(p-chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine ChemIDplus 3-(p-chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin ChemIDplus N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine ChEMBL clofazimina ChemIDplus clofazimine ChemIDplus clofaziminum ChemIDplus An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). CHEBI:13800 CHEBI:13801 CHEBI:22209 CHEBI:2426 KEGG:C00174 Acid acid chebi_ontology Saeure Saeuren acide acido acids CHEBI:37527 acid CHEBI:37527 Acid KEGG_COMPOUND acid IUPAC Saeure ChEBI Saeuren ChEBI acide IUPAC acido ChEBI acids ChEBI Derivatives of diazene with the general structure R-N=N-R'. azo compounds chebi_ontology azo compounds CHEBI:37533 azo compound CHEBI:37533 azo compounds IUPAC azo compounds ChEBI A molecular entity consisting of two or more chemical elements. chebi_ontology chemical compound heteroatomic molecular entities CHEBI:37577 heteroatomic molecular entity CHEBI:37577 chemical compound ChEBI heteroatomic molecular entities ChEBI Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements. Wikipedia:Halide chebi_ontology halides CHEBI:37578 halide CHEBI:37578 halides ChEBI An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. 0 CNOR3 42.01680 41.99799 [*]C(=O)N([*])[*] CHEBI:35354 CHEBI:35355 carboxamides chebi_ontology carboxamides primary carboxamide CHEBI:37622 carboxamide CHEBI:37622 carboxamides IUPAC carboxamides ChEBI primary carboxamide ChEBI 0 C6H12O6 180.156 180.06339 Beilstein:1724626 CAS:921-60-8 L-gluco-hexose L-glucose chebi_ontology L(-)-glucose CHEBI:37624 L-glucose CHEBI:37624 Beilstein:1724626 ChemIDplus CAS:921-60-8 ChemIDplus L-gluco-hexose IUPAC L-glucose IUPAC L(-)-glucose ChemIDplus The L-enantiomer of glucopyranose. 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m0/s1 WQZGKKKJIJFFOK-ZZWDRFIYSA-N 180.15588 180.06339 OC[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@H]1O Beilstein:2206321 GlyTouCan:G16038XU Reaxys:2206321 L-glucopyranose chebi_ontology WURCS=2.0/1,1,0/[a1211h-1x_1-5]/1/ CHEBI:37627 L-glucopyranose CHEBI:37627 Beilstein:2206321 Beilstein Reaxys:2206321 Reaxys L-glucopyranose IUPAC L-glucopyranose UniProt WURCS=2.0/1,1,0/[a1211h-1x_1-5]/1/ GlyTouCan A L-glucopyranose with an alpha-configuration at the anomeric position. 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m0/s1 WQZGKKKJIJFFOK-MDMQIMBFSA-N 180.15588 180.06339 OC[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O Beilstein:1907372 GlyTouCan:G15768VA Reaxys:1907372 alpha-L-glucopyranose chebi_ontology WURCS=2.0/1,1,0/[a1211h-1a_1-5]/1/ CHEBI:37630 alpha-L-glucose CHEBI:37630 Beilstein:1907372 Beilstein Reaxys:1907372 Reaxys alpha-L-glucopyranose IUPAC WURCS=2.0/1,1,0/[a1211h-1a_1-5]/1/ GlyTouCan 0 C6H12O6 180.156 180.06339 glucopyranose chebi_ontology CHEBI:37661 glucopyranose CHEBI:37661 glucopyranose IUPAC A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). Wikipedia:Protease_inhibitor_(biology) chebi_ontology protease inhibitors CHEBI:37670 protease inhibitor CHEBI:37670 protease inhibitors ChEBI An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. chebi_ontology protein kinase inhibitors CHEBI:37699 protein kinase inhibitor CHEBI:37699 protein kinase inhibitors ChEBI CHEBI:26019 chebi_ontology CHEBI:37734 phosphoric ester CHEBI:37734 A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration. 0 C8H11NO3S InChI=1S/C8H11NO3S/c1-8(2)6(7(11)12)9-4(10)3-5(9)13-8/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1 RBKMMJSQKNKNEV-RITPCOANSA-N 201.24388 201.04596 [H][C@@]12CC(=O)N1[C@@H](C(O)=O)C(C)(C)S2 Beilstein:4677775 CAS:87-53-6 Reaxys:4677775 2,2-dimethylpenam-3alpha-carboxylic acid penicillanic acid chebi_ontology (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid CHEBI:37806 penicillanic acid CHEBI:37806 Beilstein:4677775 Beilstein CAS:87-53-6 ChemIDplus Reaxys:4677775 Reaxys 2,2-dimethylpenam-3alpha-carboxylic acid IUPAC penicillanic acid ChemIDplus (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC sulfuric acid derivative chebi_ontology sulfuric acid derivatives CHEBI:37826 sulfuric acid derivative CHEBI:37826 sulfuric acid derivative ChEBI sulfuric acid derivatives ChEBI A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid. carboacyl groups carboxylic acyl group chebi_ontology carboxylic acyl groups CHEBI:37838 carboacyl group CHEBI:37838 carboacyl groups IUPAC carboxylic acyl group IUPAC carboxylic acyl groups IUPAC A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. CHEBI:26158 Wikipedia:Phytohormone chebi_ontology phytohormone phytohormones plant growth factor plant growth factors plant growth hormone plant growth hormones plant hormones CHEBI:37848 plant hormone CHEBI:37848 phytohormone ChEBI phytohormones ChEBI plant growth factor ChEBI plant growth factors ChEBI plant growth hormone ChEBI plant growth hormones ChEBI plant hormones ChEBI chebi_ontology organoammonium sulfates CHEBI:37852 organoammonium sulfate salt CHEBI:37852 organoammonium sulfates ChEBI Any coumarin carrying at least one hydroxy substituent. CHEBI:24691 CHEBI:24692 chebi_ontology hydroxycoumarins CHEBI:37912 hydroxycoumarin CHEBI:37912 hydroxycoumarins ChEBI A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa. 0 C52H97N16O13R 1154.428 1153.74210 C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)NCC1)[C@@H](C)O)=O)CCN)=O)CCN)=O)CC(C)C)=O)CC(C)C)=O)CCN)=O)=O)CCN)=O)[C@@H](C)O)=O)CCN)=O)CCC[C@@H](C*)C CHEBI:34651 CHEBI:472593 CHEBI:560465 CHEBI:566816 CHEBI:596826 CHEBI:597111 CHEBI:600596 CHEBI:659853 CAS:1066-17-7 CAS:1264-72-8 DrugBank:DB00803 KEGG:C13768 KEGG:D02138 PMID:15825037 PMID:16931410 PMID:17145797 PMID:17562800 PMID:17576842 PMID:17606684 PMID:17620384 PMID:17646423 PMID:17846127 PMID:17876007 PMID:18625681 PMID:25322351 PMID:26252512 PMID:26415906 PMID:26488563 PMID:26730548 PMID:27160031 PMID:27411324 PMID:27480806 PMID:27524102 PMID:27552304 PMID:27684296 PMID:27743779 PMID:27790432 PMID:27793510 PMID:27891118 PMID:27917926 PMID:28018876 PMID:28029008 PMID:28215823 PMID:28257552 PMID:28267594 PMID:28267779 PMID:28300674 PMID:28315729 PMID:28321410 Colistin chebi_ontology colistina colistine colistinum polymyxin E CHEBI:37943 colistin CHEBI:37943 CAS:1066-17-7 ChemIDplus CAS:1264-72-8 ChemIDplus CAS:1264-72-8 KEGG COMPOUND PMID:15825037 Europe PMC PMID:16931410 Europe PMC PMID:17145797 ChEMBL PMID:17562800 ChEMBL PMID:17576842 ChEMBL PMID:17606684 ChEMBL PMID:17620384 ChEMBL PMID:17646423 ChEMBL PMID:17846127 ChEMBL PMID:17876007 ChEMBL PMID:18625681 Europe PMC PMID:25322351 Europe PMC PMID:26252512 Europe PMC PMID:26415906 Europe PMC PMID:26488563 Europe PMC PMID:26730548 Europe PMC PMID:27160031 Europe PMC PMID:27411324 Europe PMC PMID:27480806 Europe PMC PMID:27524102 Europe PMC PMID:27552304 Europe PMC PMID:27684296 Europe PMC PMID:27743779 Europe PMC PMID:27790432 Europe PMC PMID:27793510 Europe PMC PMID:27891118 Europe PMC PMID:27917926 Europe PMC PMID:28018876 Europe PMC PMID:28029008 Europe PMC PMID:28215823 Europe PMC PMID:28257552 Europe PMC PMID:28267594 Europe PMC PMID:28267779 Europe PMC PMID:28300674 Europe PMC PMID:28315729 Europe PMC PMID:28321410 Europe PMC Colistin ChEMBL colistina ChemIDplus colistine ChemIDplus colistinum ChemIDplus polymyxin E ChemIDplus A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. chebi_ontology oxaspiro compounds CHEBI:37948 oxaspiro compound CHEBI:37948 oxaspiro compounds ChEBI chebi_ontology Farbstoff Farbstoffe colorante colorantes dyes teinture teintures CHEBI:37958 dye CHEBI:37958 Farbstoff ChEBI Farbstoffe ChEBI colorante ChEBI colorantes ChEBI dyes ChEBI teinture ChEBI teintures ChEBI chebi_ontology aminoglycoside sulfate salts CHEBI:38012 aminoglycoside sulfate salt CHEBI:38012 aminoglycoside sulfate salts ChEBI A carbopolyclic compound comprising of three carbocyclic rings. chebi_ontology carbotricyclic compounds CHEBI:38032 carbotricyclic compound CHEBI:38032 carbotricyclic compounds ChEBI A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. chebi_ontology antimalarials CHEBI:38068 antimalarial CHEBI:38068 antimalarials ChEBI A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. chebi_ontology anti-arrhythmia agent antiarrhythmic agent CHEBI:38070 anti-arrhythmia drug CHEBI:38070 anti-arrhythmia agent ChEBI antiarrhythmic agent ChEBI chebi_ontology CHEBI:38099 thiadiazoles CHEBI:38099 Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. chebi_ontology heterocyclic organonitrogen compounds organonitrogen heterocyclic compounds CHEBI:38101 organonitrogen heterocyclic compound CHEBI:38101 heterocyclic organonitrogen compounds ChEBI organonitrogen heterocyclic compounds ChEBI Compounds based on a triazine skeleton. chebi_ontology CHEBI:38102 triazines CHEBI:38102 Any organic heterocyclic compound containing at least one ring oxygen atom. PMID:17134300 chebi_ontology heterocyclic organooxygen compounds organooxygen heterocyclic compounds oxacycles CHEBI:38104 oxacycle CHEBI:38104 PMID:17134300 Europe PMC heterocyclic organooxygen compounds ChEBI organooxygen heterocyclic compounds ChEBI oxacycles ChEBI chebi_ontology heterocyclic organosulfur compounds organosulfur heterocyclic compounds CHEBI:38106 organosulfur heterocyclic compound CHEBI:38106 heterocyclic organosulfur compounds ChEBI organosulfur heterocyclic compounds ChEBI 0 C11H12N2S2 InChI=1S/C11H12N2S2/c1-15-11(14)13-7-8-6-12-10-5-3-2-4-9(8)10/h2-6,12H,7H2,1H3,(H,13,14) QYKQWFZDEDFELK-UHFFFAOYSA-N 236.35846 236.04419 CSC(=S)NCc1c[nH]c2ccccc12 Beilstein:3611293 CAS:105748-59-2 methyl (1H-indol-3-ylmethyl)carbamodithioate chebi_ontology Brassinine methyl (1H-indol-3-ylmethyl)dithiocarbamate CHEBI:38119 brassinin CHEBI:38119 Beilstein:3611293 Beilstein CAS:105748-59-2 ChemIDplus methyl (1H-indol-3-ylmethyl)carbamodithioate IUPAC Brassinine ChemIDplus methyl (1H-indol-3-ylmethyl)dithiocarbamate IUPAC Any organonitrogen compound with formula RS-C(=X)NH2 where X = O (monothiocarbamic esters) or S (dithiocarbamic esters), or their N-substituted derivatives. thiocarbamic ester chebi_ontology thiocarbamate thiocarbamates CHEBI:38127 thiocarbamic ester CHEBI:38127 thiocarbamic ester ChEBI thiocarbamate ChEBI thiocarbamates ChEBI Any ester derived from a member of the class of dithiocarbamic acids by formal replacement of the -SH group by -SR, where R is an organyl group. dithiocarbamic ester chebi_ontology carbamodithioates carbamodithioic esters dithiocarbamoates CHEBI:38129 dithiocarbamic ester CHEBI:38129 dithiocarbamic ester ChEBI carbamodithioates ChEBI carbamodithioic esters ChEBI dithiocarbamoates ChEBI Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues. Wikipedia:Lactol lactol lactols chebi_ontology lactols CHEBI:38131 lactol CHEBI:38131 lactol IUPAC lactols IUPAC lactols ChEBI A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. CHEBI:23090 CHEBI:3585 CHEBI:6789 KEGG:C00917 KEGG:C02169 chebi_ontology Chelating agent Metal chelator chelating agents chelators complexon CHEBI:38161 chelator CHEBI:38161 Chelating agent KEGG_COMPOUND Metal chelator KEGG_COMPOUND chelating agents ChEBI chelators ChEBI complexon ChEBI chebi_ontology organic heterotetracyclic compounds CHEBI:38163 organic heterotetracyclic compound CHEBI:38163 organic heterotetracyclic compounds ChEBI chebi_ontology organic heteropentacyclic compounds CHEBI:38164 organic heteropentacyclic compound CHEBI:38164 organic heteropentacyclic compounds ChEBI CHEBI:25429 CHEBI:38075 chebi_ontology organic heteropolycyclic compounds CHEBI:38166 organic heteropolycyclic compound CHEBI:38166 organic heteropolycyclic compounds ChEBI chebi_ontology monocyclic heteroarenes CHEBI:38179 monocyclic heteroarene CHEBI:38179 monocyclic heteroarenes ChEBI chebi_ontology polycyclic heteroarenes CHEBI:38180 polycyclic heteroarene CHEBI:38180 polycyclic heteroarenes ChEBI A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'. chebi_ontology pyridinemonocarboxylates CHEBI:38181 pyridinemonocarboxylate CHEBI:38181 pyridinemonocarboxylates ChEBI A pyridinemonocarboxylate resulting from the deprotonation of the carboxy group of isonicotinic acid. -1 C6H4NO2 InChI=1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)/p-1 TWBYWOBDOCUKOW-UHFFFAOYSA-M 122.104 122.02475 C(=O)(C=1C=CN=CC1)[O-] MetaCyc:CPD-13335 pyridine-4-carboxylate chebi_ontology 4-picolinate 4-pyridinecarboxylate gamma-picolinate CHEBI:38186 isonicotinate CHEBI:38186 pyridine-4-carboxylate IUPAC 4-picolinate MetaCyc 4-pyridinecarboxylate MetaCyc gamma-picolinate MetaCyc One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. chebi_ontology calcium channel antagonist calcium channel antagonists calcium channel blockers CHEBI:38215 calcium channel blocker CHEBI:38215 calcium channel antagonist ChEBI calcium channel antagonists ChEBI calcium channel blockers ChEBI -2 C32H22N6O6S2 InChI=1S/C32H24N6O6S2/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44)/p-2 HFHIDKQMGIGARX-UHFFFAOYSA-L 650.68592 650.10532 Nc1c(cc(c2ccccc12)S([O-])(=O)=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1cc(c2ccccc2c1N)S([O-])(=O)=O Beilstein:1838279 Gmelin:340935 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) chebi_ontology CHEBI:38216 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) CHEBI:38216 Beilstein:1838279 Beilstein Gmelin:340935 Gmelin 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) IUPAC 0 C32H24N6O6S2 InChI=1S/C32H24N6O6S2/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44) HFHIDKQMGIGARX-UHFFFAOYSA-N 652.70180 652.11987 Nc1c(cc(c2ccccc12)S(O)(=O)=O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1cc(c2ccccc2c1N)S(O)(=O)=O CHEBI:291121 Beilstein:741249 Gmelin:287844 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid) chebi_ontology congo red CHEBI:38217 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid) CHEBI:38217 Beilstein:741249 Beilstein Gmelin:287844 Gmelin 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid) IUPAC congo red ChEMBL 0 C8H4N2 InChI=1S/C8H4N2/c9-5-7-2-1-3-8(4-7)6-10/h1-4H LAQPNDIUHRHNCV-UHFFFAOYSA-N 128.13084 128.03745 N#Cc1cccc(c1)C#N Beilstein:2038364 CAS:626-17-5 benzene-1,3-dicarbonitrile chebi_ontology 1,3-Benzenedicarbonitrile 1,3-Dicyanobenzene 3-Cyanobenzonitrile IPN Isophthalodinitrile m-Dicyanobenzene CHEBI:38218 isophthalonitrile CHEBI:38218 Beilstein:2038364 Beilstein CAS:626-17-5 ChemIDplus CAS:626-17-5 NIST Chemistry WebBook benzene-1,3-dicarbonitrile IUPAC 1,3-Benzenedicarbonitrile NIST_Chemistry_WebBook 1,3-Dicyanobenzene ChemIDplus 3-Cyanobenzonitrile ChemIDplus IPN NIST_Chemistry_WebBook Isophthalodinitrile NIST_Chemistry_WebBook m-Dicyanobenzene ChemIDplus Any toxin produced by a plant. chebi_ontology phytotoxins CHEBI:38231 phytotoxin CHEBI:38231 phytotoxins ChEBI Any of a class of heterocyclic amines having a saturated five-membered ring. CHEBI:26922 CHEBI:38191 chebi_ontology CHEBI:38260 pyrrolidines CHEBI:38260 chebi_ontology CHEBI:38261 imidazolidines CHEBI:38261 chebi_ontology azabicycloalkanes CHEBI:38295 azabicycloalkane CHEBI:38295 azabicycloalkanes ChEBI chebi_ontology CHEBI:38298 benzodioxoles CHEBI:38298 chebi_ontology diazolidines CHEBI:38304 diazolidine CHEBI:38304 diazolidines ChEBI chebi_ontology cephems CHEBI:38311 cephem CHEBI:38311 cephems ChEBI Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure). chebi_ontology CHEBI:38313 diazines CHEBI:38313 chebi_ontology CHEBI:38314 pyrazines CHEBI:38314 chebi_ontology CHEBI:38329 oxazolidines CHEBI:38329 A pyrimidine carrying one or more oxo substituents. chebi_ontology pyrimidones CHEBI:38337 pyrimidone CHEBI:38337 pyrimidones ChEBI A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives. chebi_ontology aminopyrimidines CHEBI:38338 aminopyrimidine CHEBI:38338 aminopyrimidines ChEBI CHEBI:26949 CHEBI:38417 1,3-thiazoles chebi_ontology CHEBI:38418 1,3-thiazoles CHEBI:38418 1,3-thiazoles ChEBI chebi_ontology 1-benzopyrans CHEBI:38443 1-benzopyran CHEBI:38443 1-benzopyrans ChEBI chebi_ontology chromenones CHEBI:38445 chromenone CHEBI:38445 chromenones ChEBI chebi_ontology CHEBI:38496 electron-transport chain inhibitor CHEBI:38496 chebi_ontology CHEBI:38497 respiratory-chain inhibitor CHEBI:38497 chebi_ontology mitochondrial NADH dehydrogenase inhibitor mitochondrial complex I inhibitor mitochondrial complex I inhibitors CHEBI:38498 mitochondrial NADH:ubiquinone reductase inhibitor CHEBI:38498 mitochondrial NADH dehydrogenase inhibitor ChEBI mitochondrial complex I inhibitor ChEBI mitochondrial complex I inhibitors ChEBI chebi_ontology mitochondrial complex III inhibitor mitochondrial complex III inhibitors CHEBI:38499 mitochondrial cytochrome-bc1 complex inhibitor CHEBI:38499 mitochondrial complex III inhibitor ChEBI mitochondrial complex III inhibitors ChEBI An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1). CHEBI:38501 CHEBI:62966 PMID:12969439 Wikipedia:Cytochrome_c_oxidase chebi_ontology CcO inhibitor EC 1.9.3.1 (cytochrome c oxidase) inhibitors EC 1.9.3.1 inhibitor EC 1.9.3.1 inhibitors NADH cytochrome c oxidase inhibitor NADH cytochrome c oxidase inhibitors Warburg's respiratory enzyme inhibitor Warburg's respiratory enzyme inhibitors complex IV (mitochondrial electron transport) inhibitor complex IV (mitochondrial electron transport) inhibitors cytochrome a3 inhibitor cytochrome a3 inhibitors cytochrome aa3 inhibitor cytochrome aa3 inhibitors cytochrome c oxidase (EC 1.9.3.1) inhibitor cytochrome c oxidase (EC 1.9.3.1) inhibitors cytochrome c oxidase inhibitor cytochrome c oxidase inhibitors cytochrome oxidase inhibitor cytochrome oxidase inhibitors cytochrome-c oxidase inhibitor cytochrome-c oxidase inhibitors ferrocytochrome c oxidase inhibitor ferrocytochrome c oxidase inhibitors ferrocytochrome-c:oxygen oxidoreductase inhibitor ferrocytochrome-c:oxygen oxidoreductase inhibitors indophenol oxidase inhibitor indophenol oxidase inhibitors indophenolase inhibitor indophenolase inhibitors mitochondrial complex IV inhibitor mitochondrial complex IV inhibitors mitochondrial cytochrome-c oxidase inhibitors CHEBI:38500 EC 1.9.3.1 (cytochrome c oxidase) inhibitor CHEBI:38500 PMID:12969439 Europe PMC CcO inhibitor ChEBI EC 1.9.3.1 (cytochrome c oxidase) inhibitors ChEBI EC 1.9.3.1 inhibitor ChEBI EC 1.9.3.1 inhibitors ChEBI NADH cytochrome c oxidase inhibitor ChEBI NADH cytochrome c oxidase inhibitors ChEBI Warburg's respiratory enzyme inhibitor ChEBI Warburg's respiratory enzyme inhibitors ChEBI complex IV (mitochondrial electron transport) inhibitor ChEBI complex IV (mitochondrial electron transport) inhibitors ChEBI cytochrome a3 inhibitor ChEBI cytochrome a3 inhibitors ChEBI cytochrome aa3 inhibitor ChEBI cytochrome aa3 inhibitors ChEBI cytochrome c oxidase (EC 1.9.3.1) inhibitor ChEBI cytochrome c oxidase (EC 1.9.3.1) inhibitors ChEBI cytochrome c oxidase inhibitor ChEBI cytochrome c oxidase inhibitors ChEBI cytochrome oxidase inhibitor ChEBI cytochrome oxidase inhibitors ChEBI cytochrome-c oxidase inhibitor ChEBI cytochrome-c oxidase inhibitors ChEBI ferrocytochrome c oxidase inhibitor ChEBI ferrocytochrome c oxidase inhibitors ChEBI ferrocytochrome-c:oxygen oxidoreductase inhibitor ChEBI ferrocytochrome-c:oxygen oxidoreductase inhibitors ChEBI indophenol oxidase inhibitor ChEBI indophenol oxidase inhibitors ChEBI indophenolase inhibitor ChEBI indophenolase inhibitors ChEBI mitochondrial complex IV inhibitor ChEBI mitochondrial complex IV inhibitors ChEBI mitochondrial cytochrome-c oxidase inhibitors ChEBI chebi_ontology CHEBI:38502 cytochrome-bc1 complex inhibitor CHEBI:38502 A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3. Wikipedia:NADH_dehydrogenase_(ubiquinone) chebi_ontology DPNH-coenzyme Q reductase inhibitor DPNH-ubiquinone reductase inhibitor EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors EC 1.6.5.3 inhibitor EC 1.6.5.3 inhibitors NADH coenzyme Q1 reductase inhibitor NADH coenzyme Q1 reductase inhibitors NADH dehydrogenase (ubiquinone) inhibitor NADH dehydrogenase (ubiquinone) inhibitors NADH-CoQ oxidoreductase inhibitor NADH-CoQ oxidoreductase inhibitors NADH-CoQ reductase inhibitor NADH-CoQ reductase inhibitors NADH-Q6 oxidoreductase inhibitor NADH-coenzyme Q oxidoreductase inhibitors NADH-coenzyme Q reductase inhibitor NADH-coenzyme Q reductase inhibitors NADH-ubiquinone oxidoreductase inhibitor NADH-ubiquinone oxidoreductase inhibitors NADH-ubiquinone reductase inhibitor NADH-ubiquinone reductase inhibitors NADH-ubiquinone-1 reductase inhibitor NADH-ubiquinone-1 reductase inhibitors NADH2 dehydrogenase (ubiquinone) inhibitor NADH:ubiquinone oxidoreductase complex inhibitor NADH:ubiquinone oxidoreductase inhibitor NADH:ubiquinone oxidoreductase inhibitors NADH:ubiquinone reductase (H(+)-translocating) inhibitor NADH:ubiquinone reductase (H(+)-translocating) inhibitors NADH:ubiquinone reductase (H+-translocating) inhibitor NADH:ubiquinone reductase inhibitor coenzyme Q reductase complex 1 dehydrogenase inhibitor complex I (NADH:Q1 oxidoreductase) inhibitors complex I (electron transport chain) inhibitors complex I (mitochondrial electron transport) inhibitors dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor electron transfer complex I inhibitor electron transfer complex I inhibitors mitochondrial electron transport complex 1 inhibitor mitochondrial electron transport complex I inhibitor mitochondrial electron transport complex I inhibitors reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors type 1 dehydrogenase inhibitor type 1 dehydrogenase inhibitors ubiquinone reductase inhibitor ubiquinone reductase inhibitors CHEBI:38503 EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor CHEBI:38503 DPNH-coenzyme Q reductase inhibitor ChEBI DPNH-ubiquinone reductase inhibitor ChEBI EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor ChEBI EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors ChEBI EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors ChEBI EC 1.6.5.3 inhibitor ChEBI EC 1.6.5.3 inhibitors ChEBI NADH coenzyme Q1 reductase inhibitor ChEBI NADH coenzyme Q1 reductase inhibitors ChEBI NADH dehydrogenase (ubiquinone) inhibitor ChEBI NADH dehydrogenase (ubiquinone) inhibitors ChEBI NADH-CoQ oxidoreductase inhibitor ChEBI NADH-CoQ oxidoreductase inhibitors ChEBI NADH-CoQ reductase inhibitor ChEBI NADH-CoQ reductase inhibitors ChEBI NADH-Q6 oxidoreductase inhibitor ChEBI NADH-coenzyme Q oxidoreductase inhibitors ChEBI NADH-coenzyme Q reductase inhibitor ChEBI NADH-coenzyme Q reductase inhibitors ChEBI NADH-ubiquinone oxidoreductase inhibitor ChEBI NADH-ubiquinone oxidoreductase inhibitors ChEBI NADH-ubiquinone reductase inhibitor ChEBI NADH-ubiquinone reductase inhibitors ChEBI NADH-ubiquinone-1 reductase inhibitor ChEBI NADH-ubiquinone-1 reductase inhibitors ChEBI NADH2 dehydrogenase (ubiquinone) inhibitor ChEBI NADH:ubiquinone oxidoreductase complex inhibitor ChEBI NADH:ubiquinone oxidoreductase inhibitor ChEBI NADH:ubiquinone oxidoreductase inhibitors ChEBI NADH:ubiquinone reductase (H(+)-translocating) inhibitor ChEBI NADH:ubiquinone reductase (H(+)-translocating) inhibitors ChEBI NADH:ubiquinone reductase (H+-translocating) inhibitor ChEBI NADH:ubiquinone reductase inhibitor ChEBI coenzyme Q reductase ChEBI complex 1 dehydrogenase inhibitor ChEBI complex I (NADH:Q1 oxidoreductase) inhibitors ChEBI complex I (electron transport chain) inhibitors ChEBI complex I (mitochondrial electron transport) inhibitors ChEBI dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor ChEBI electron transfer complex I inhibitor ChEBI electron transfer complex I inhibitors ChEBI mitochondrial electron transport complex 1 inhibitor ChEBI mitochondrial electron transport complex I inhibitor ChEBI mitochondrial electron transport complex I inhibitors ChEBI reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor ChEBI reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors ChEBI type 1 dehydrogenase inhibitor ChEBI type 1 dehydrogenase inhibitors ChEBI ubiquinone reductase inhibitor ChEBI ubiquinone reductase inhibitors ChEBI Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues). hydrazones chebi_ontology hydrazones CHEBI:38532 hydrazone CHEBI:38532 hydrazones IUPAC hydrazones ChEBI Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms. difluorobenzene chebi_ontology Difluorbenzol difluorobenzenes CHEBI:38582 difluorobenzene CHEBI:38582 difluorobenzene IUPAC Difluorbenzol ChEBI difluorobenzenes ChEBI A difluorobenzene carrying fluoro groups at positions 1 and 3. 0 C6H4F2 InChI=1S/C6H4F2/c7-5-2-1-3-6(8)4-5/h1-4H UEMGWPRHOOEKTA-UHFFFAOYSA-N 114.09277 114.02811 Fc1cccc(F)c1 Beilstein:1904537 CAS:372-18-9 Gmelin:200891 PMID:15535712 PMID:22707282 Patent:CN101607874 Patent:CN1634895 Patent:CN1765887 Reaxys:1904537 1,3-difluorobenzene chebi_ontology 1,3-Difluorbenzol m-difluorobenzene meta-difluorobenzene CHEBI:38584 1,3-difluorobenzene CHEBI:38584 Beilstein:1904537 Beilstein CAS:372-18-9 ChemIDplus CAS:372-18-9 NIST Chemistry WebBook Gmelin:200891 Gmelin PMID:15535712 Europe PMC PMID:22707282 Europe PMC Reaxys:1904537 Reaxys 1,3-difluorobenzene IUPAC 1,3-Difluorbenzol ChEBI m-difluorobenzene ChemIDplus meta-difluorobenzene NIST_Chemistry_WebBook 0 C2H3N3 69.065 69.03270 triazole chebi_ontology CHEBI:38597 triazole CHEBI:38597 triazole IUPAC An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4). Wikipedia:Monoamine_oxidase_inhibitor chebi_ontology EC 1.4.3.4 (monoamine oxidase) inhibitors EC 1.4.3.4 inhibitor EC 1.4.3.4 inhibitors MAO A inhibitor MAO A inhibitors MAO B inhibitor MAO B inhibitors MAO inhibitor MAO inhibitors MAO-A inhibitor MAO-A inhibitors MAO-B inhibitor MAO-B inhibitors adrenalin oxidase inhibitor adrenalin oxidase inhibitors adrenaline oxidase inhibitor adrenaline oxidase inhibitors amine oxidase (flavin-containing) inhibitor amine oxidase (flavin-containing) inhibitors amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors amine:oxygen oxidoreductase (deaminating) inhibitor amine:oxygen oxidoreductase (deaminating) inhibitors epinephrine oxidase inhibitor epinephrine oxidase inhibitors monoamine oxidase (EC 1.4.3.4) inhibitor monoamine oxidase (EC 1.4.3.4) inhibitors monoamine oxidase A inhibitor monoamine oxidase A inhibitors monoamine oxidase B inhibitor monoamine oxidase B inhibitors monoamine oxidase inhibitor monoamine oxidase inhibitors monoamine:O2 oxidoreductase (deaminating) inhibitor monoamine:O2 oxidoreductase (deaminating) inhibitors serotonin deaminase inhibitor serotonin deaminase inhibitors tyraminase inhibitor tyraminase inhibitors tyramine oxidase inhibitor tyramine oxidase inhibitors CHEBI:38623 EC 1.4.3.4 (monoamine oxidase) inhibitor CHEBI:38623 EC 1.4.3.4 (monoamine oxidase) inhibitors ChEBI EC 1.4.3.4 inhibitor ChEBI EC 1.4.3.4 inhibitors ChEBI MAO A inhibitor ChEBI MAO A inhibitors ChEBI MAO B inhibitor ChEBI MAO B inhibitors ChEBI MAO inhibitor ChEBI MAO inhibitors ChEBI MAO-A inhibitor ChEBI MAO-A inhibitors ChEBI MAO-B inhibitor ChEBI MAO-B inhibitors ChEBI adrenalin oxidase inhibitor ChEBI adrenalin oxidase inhibitors ChEBI adrenaline oxidase inhibitor ChEBI adrenaline oxidase inhibitors ChEBI amine oxidase (flavin-containing) inhibitor ChEBI amine oxidase (flavin-containing) inhibitors ChEBI amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor ChEBI amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors ChEBI amine:oxygen oxidoreductase (deaminating) inhibitor ChEBI amine:oxygen oxidoreductase (deaminating) inhibitors ChEBI epinephrine oxidase inhibitor ChEBI epinephrine oxidase inhibitors ChEBI monoamine oxidase (EC 1.4.3.4) inhibitor ChEBI monoamine oxidase (EC 1.4.3.4) inhibitors ChEBI monoamine oxidase A inhibitor ChEBI monoamine oxidase A inhibitors ChEBI monoamine oxidase B inhibitor ChEBI monoamine oxidase B inhibitors ChEBI monoamine oxidase inhibitor ChEBI monoamine oxidase inhibitors ChEBI monoamine:O2 oxidoreductase (deaminating) inhibitor ChEBI monoamine:O2 oxidoreductase (deaminating) inhibitors ChEBI serotonin deaminase inhibitor ChEBI serotonin deaminase inhibitors ChEBI tyraminase inhibitor ChEBI tyraminase inhibitors ChEBI tyramine oxidase inhibitor ChEBI tyramine oxidase inhibitors ChEBI Any agent that affects the transport of molecular entities across a biological membrane. chebi_ontology membrane transport modulators CHEBI:38632 membrane transport modulator CHEBI:38632 membrane transport modulators ChEBI organic sodium salt chebi_ontology organic sodium salts CHEBI:38700 organic sodium salt CHEBI:38700 organic sodium salt ChEBI organic sodium salts ChEBI chebi_ontology inorganic sodium salts CHEBI:38702 inorganic sodium salt CHEBI:38702 inorganic sodium salts ChEBI Any dianion containing at least one carboxy group. carboxylic acid dianion chebi_ontology carboxylic acid dianions CHEBI:38716 carboxylic acid dianion CHEBI:38716 carboxylic acid dianion ChEBI carboxylic acid dianions ChEBI A monocarboxylic acid anion that is the monoanion obtained by the deprotonation of the carboxy group attached to the quinoline skeleton chebi_ontology quinolinemonocarboxylates CHEBI:38773 quinolinemonocarboxylate CHEBI:38773 quinolinemonocarboxylates ChEBI Any compound containing morpholine as part of its structure. chebi_ontology CHEBI:38785 morpholines CHEBI:38785 A membrane transport modulator that is able to regulate intracellular calcium levels. chebi_ontology calcium channel modulators CHEBI:38808 calcium channel modulator CHEBI:38808 calcium channel modulators ChEBI Any organic heterotricyclic compound based on a dibenzofuran skeleton and its substituted derivatives thereof. chebi_ontology CHEBI:38922 dibenzofurans CHEBI:38922 A molecular entity capable of donating a hydron to an acceptor (Bronsted base). Bronsted acid chebi_ontology Bronsted-Saeure acide de Bronsted donneur d'hydron hydron donor CHEBI:39141 Bronsted acid CHEBI:39141 Bronsted acid IUPAC Bronsted-Saeure ChEBI acide de Bronsted IUPAC donneur d'hydron IUPAC hydron donor IUPAC A molecular entity capable of accepting a hydron from a donor (Bronsted acid). Bronsted base chebi_ontology Bronsted-Base accepteur d'hydron base de Bronsted hydron acceptor CHEBI:39142 Bronsted base CHEBI:39142 Bronsted base IUPAC Bronsted-Base ChEBI accepteur d'hydron IUPAC base de Bronsted IUPAC hydron acceptor IUPAC A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. Lewis base chebi_ontology Lewis-Base base de Lewis donneur d'une paire d'electrons electron donor CHEBI:39144 Lewis base CHEBI:39144 Lewis base IUPAC Lewis-Base ChEBI base de Lewis IUPAC donneur d'une paire d'electrons ChEBI electron donor ChEBI trichostatin chebi_ontology trichostatins CHEBI:39146 trichostatin CHEBI:39146 trichostatin ChEBI trichostatins ChEBI 0 C17H21NO3 InChI=1S/C17H21NO3/c1-12(5-10-16(19)20)11-13(2)17(21)14-6-8-15(9-7-14)18(3)4/h5-11,13H,1-4H3,(H,19,20)/b10-5+,12-11+ VKEITMNFEJHFCX-WKWSCTOISA-N 287.35358 287.15214 CC(C(=O)c1ccc(cc1)N(C)C)\C=C(C)\C=C\C(O)=O Beilstein:2386556 CAS:114127-17-2 (2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid trichostatic acid chebi_ontology (+-)-7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxo-2,4-heptadienoic acid CHEBI:39157 trichostatic acid CHEBI:39157 Beilstein:2386556 Beilstein CAS:114127-17-2 ChemIDplus (2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid IUPAC trichostatic acid ChemIDplus (+-)-7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxo-2,4-heptadienoic acid ChemIDplus 0 C17H21NO3 InChI=1S/C17H21NO3/c1-12(5-10-16(19)20)11-13(2)17(21)14-6-8-15(9-7-14)18(3)4/h5-11,13H,1-4H3,(H,19,20)/b10-5+,12-11+/t13-/m1/s1 VKEITMNFEJHFCX-QEQCGCAPSA-N 287.35358 287.15214 C[C@@H](C(=O)c1ccc(cc1)N(C)C)\C=C(C)\C=C\C(O)=O Beilstein:5284073 Beilstein:6893749 (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid chebi_ontology (+)-Trichostatsaeure (+)-trichostatic acid CHEBI:39158 (R)-trichostatic acid CHEBI:39158 Beilstein:5284073 Beilstein Beilstein:6893749 Beilstein (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid IUPAC (+)-Trichostatsaeure ChEBI (+)-trichostatic acid ChEBI 0 C17H21NO3 InChI=1S/C17H21NO3/c1-12(5-10-16(19)20)11-13(2)17(21)14-6-8-15(9-7-14)18(3)4/h5-11,13H,1-4H3,(H,19,20)/b10-5+,12-11+/t13-/m0/s1 VKEITMNFEJHFCX-LEJRBOCMSA-N 287.35358 287.15214 C[C@H](C(=O)c1ccc(cc1)N(C)C)\C=C(C)\C=C\C(O)=O Beilstein:5284074 (2E,4E,6S)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid chebi_ontology (-)-Trichostatsaeure (-)-trichostatic acid CHEBI:39159 (S)-trichostatic acid CHEBI:39159 Beilstein:5284074 Beilstein (2E,4E,6S)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid IUPAC (-)-Trichostatsaeure ChEBI (-)-trichostatic acid ChEBI Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives. chebi_ontology CHEBI:39201 phenazines CHEBI:39201 chebi_ontology CHEBI:39208 antibiotic insecticide CHEBI:39208 chebi_ontology CHEBI:39209 macrolide insecticide CHEBI:39209 chebi_ontology CHEBI:39213 avermectin insecticide CHEBI:39213 Mixture of 80% avermectin B1a and 20% avermectin B1b. CAS:71751-41-2 Abamectin chebi_ontology Agri-Mek Avid MK 936 Zephyr avermectin B1 CHEBI:39214 abamectin CHEBI:39214 CAS:71751-41-2 ChemIDplus Abamectin ChemIDplus Agri-Mek ChemIDplus Avid ChemIDplus MK 936 ChemIDplus Zephyr ChemIDplus avermectin B1 ChemIDplus chebi_ontology CHEBI:39215 antibiotic pesticide CHEBI:39215 chebi_ontology CHEBI:39216 antibiotic acaricide CHEBI:39216 chebi_ontology CHEBI:39217 antibiotic nematicide CHEBI:39217 chebi_ontology CHEBI:39218 macrolide acaricide CHEBI:39218 chebi_ontology CHEBI:39219 avermectin acaricide CHEBI:39219 chebi_ontology CHEBI:39220 avermectin pesticide CHEBI:39220 chebi_ontology CHEBI:39221 macrolide pesticide CHEBI:39221 A mixture of emamectin B1a (major component) and emamectin B1b (minor component). CAS:119791-41-2 CAS:137335-79-6 emamectin chebi_ontology (4''R)- 4''-deoxy-4''-(methylamino)avermectin B1 4''-epi-methylamino-4''-deoxyavermectin B1 CHEBI:39230 emamectin CHEBI:39230 CAS:119791-41-2 ChemIDplus CAS:137335-79-6 ChemIDplus emamectin ChemIDplus (4''R)- 4''-deoxy-4''-(methylamino)avermectin B1 ChemIDplus 4''-epi-methylamino-4''-deoxyavermectin B1 ChemIDplus 0 C49H75NO13 InChI=1S/C49H75NO13/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3/b14-13+,28-16+,33-15+/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+/m0/s1 CXEGAUYXQAKHKJ-NSBHKLITSA-N 886.11874 885.52384 [H][C@@]12C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](NC)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(O2)O[C@]([H])([C@@H](C)CC)[C@@H](C)C=C1)[C@]34O Beilstein:8671728 (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside chebi_ontology CHEBI:39231 emamectin B1a CHEBI:39231 Beilstein:8671728 Beilstein (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside IUPAC 0 C48H73NO13 InChI=1S/C48H73NO13/c1-25(2)42-28(5)17-18-47(62-42)23-34-20-33(61-47)16-15-27(4)43(26(3)13-12-14-32-24-55-45-41(50)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-11)44(31(8)57-39)60-38-21-36(53-10)40(49-9)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,16,20-24H2,1-11H3/b13-12+,27-15+,32-14+/t26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40-,41+,42+,43-,44-,45+,47+,48+/m0/s1 DXIOOXFZLKCVHK-UTAOKEBVSA-N 872.09216 871.50819 [H][C@@]12C\C=C(C)\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](NC)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\C=C\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(O2)O[C@]([H])(C(C)C)[C@@H](C)C=C1)[C@]34O (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside chebi_ontology (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside CHEBI:39232 emamectin B1b CHEBI:39232 (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside IUPAC (2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylamino)-alpha-L-arabino-hexopyranosyl]-alpha-L-arabino-hexopyranoside IUPAC chebi_ontology naphthofurans CHEBI:39270 naphthofuran CHEBI:39270 naphthofurans ChEBI Any chemical substance that inhibits the life-cycle of an organism. chebi_ontology growth regulators CHEBI:39317 growth regulator CHEBI:39317 growth regulators ChEBI Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure. PMID:20194696 chebi_ontology CHEBI:39410 1,2,4-triazines CHEBI:39410 PMID:20194696 Europe PMC Any saturated fatty acid lacking a side-chain. PMID:15644336 straight-chain saturated fatty acid chebi_ontology straight-chain saturated fatty acids CHEBI:39418 straight-chain saturated fatty acid CHEBI:39418 PMID:15644336 Europe PMC straight-chain saturated fatty acid ChEBI straight-chain saturated fatty acids ChEBI chebi_ontology dioxolanes CHEBI:39430 dioxolane CHEBI:39430 dioxolanes ChEBI A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. chebi_ontology CHEBI:39442 fluorescent probe CHEBI:39442 CHEBI:13784 CHEBI:26445 CHEBI:7263 chebi_ontology CHEBI:39446 pyrimidine ribonucleosides CHEBI:39446 Any compound having a pyrimidine as part of its structure. CHEBI:13681 CHEBI:26448 chebi_ontology CHEBI:39447 pyrimidines CHEBI:39447 Any azaalkane in which two or more carbons in the chain are replaced by nitrogen. chebi_ontology polyazaalkanes CHEBI:39474 polyazaalkane CHEBI:39474 polyazaalkanes ChEBI A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated. -1 H2O4P InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1 NBIIXXVUZAFLBC-UHFFFAOYSA-M 96.98724 96.96962 [H]OP([O-])(=O)O[H] CHEBI:29137 CHEBI:39739 DrugBank:DB02831 Gmelin:1999 PDBeChem:2HP dihydrogen(tetraoxidophosphate)(1-) dihydrogenphosphate dihydrogentetraoxophosphate(1-) dihydrogentetraoxophosphate(V) dihydroxidodioxidophosphate(1-) chebi_ontology DIHYDROGENPHOSPHATE ION H2PO4(-) [PO2(OH)2](-) CHEBI:39745 dihydrogenphosphate CHEBI:39745 Gmelin:1999 Gmelin dihydrogen(tetraoxidophosphate)(1-) IUPAC dihydrogenphosphate IUPAC dihydrogentetraoxophosphate(1-) IUPAC dihydrogentetraoxophosphate(V) IUPAC dihydroxidodioxidophosphate(1-) IUPAC DIHYDROGENPHOSPHATE ION PDBeChem H2PO4(-) IUPAC [PO2(OH)2](-) IUPAC KEGG:C02019 Cyclic ketone cyclic ketones chebi_ontology CHEBI:3992 cyclic ketone CHEBI:3992 Cyclic ketone KEGG_COMPOUND cyclic ketones IUPAC A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis). 0 C3H6N2O2 InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1 DYDCUQKUCUHJBH-UWTATZPHSA-N 102.09190 102.04293 [H][C@@]1(N)CONC1=O CHEBI:4030 Beilstein:80798 CAS:68-41-7 DrugBank:DB00260 Drug_Central:759 HMDB:HMDB0014405 KEGG:D00877 LINCS:LSM-5932 LIPID_MAPS_instance:LMPK14000007 MetaCyc:CPD-2482 PDBeChem:4AX PMID:12076471 PMID:17707326 PMID:18316423 PMID:18486041 PMID:18930757 PMID:22234379 PMID:22368237 PMID:22632472 PMID:22892161 PMID:23174090 PMID:23416058 PMID:23438729 PMID:23523746 PMID:23542909 PMID:23656850 PMID:23685206 PMID:4555420 PMID:5006234 Patent:US2772280 Patent:US2840565 Reaxys:80798 Wikipedia:Cycloserine (4R)-4-aminoisoxazolidin-3-one D-Cycloserine chebi_ontology (+)-4-amino-3-isoxazolidinone (+)-cycloserine (R)-4-AMINO-ISOXAZOLIDIN-3-ONE D-(+)-cycloserine D-4-amino-3-isoxazolidinone D-4-amino-3-isoxazolidone DCS PA 94 PA-94 Ro-1-9213 Seromycin alpha-Cycloserine cicloserina cyclo-D-serine cycloserine cycloserinum orientomycin CHEBI:40009 D-cycloserine CHEBI:40009 Beilstein:80798 Beilstein CAS:68-41-7 ChemIDplus CAS:68-41-7 NIST Chemistry WebBook Drug_Central:759 DrugCentral LIPID_MAPS_instance:LMPK14000007 LIPID MAPS PMID:12076471 Europe PMC PMID:17707326 Europe PMC PMID:18316423 Europe PMC PMID:18486041 Europe PMC PMID:18930757 Europe PMC PMID:22234379 Europe PMC PMID:22368237 Europe PMC PMID:22632472 Europe PMC PMID:22892161 Europe PMC PMID:23174090 Europe PMC PMID:23416058 Europe PMC PMID:23438729 Europe PMC PMID:23523746 Europe PMC PMID:23542909 Europe PMC PMID:23656850 Europe PMC PMID:23685206 Europe PMC PMID:4555420 Europe PMC PMID:5006234 Europe PMC Reaxys:80798 Reaxys (4R)-4-aminoisoxazolidin-3-one IUPAC D-Cycloserine ChemIDplus D-Cycloserine KEGG_COMPOUND (+)-4-amino-3-isoxazolidinone ChemIDplus (+)-cycloserine ChEBI (R)-4-AMINO-ISOXAZOLIDIN-3-ONE PDBeChem D-(+)-cycloserine ChEBI D-4-amino-3-isoxazolidinone ChemIDplus D-4-amino-3-isoxazolidone ChemIDplus DCS ChemIDplus PA 94 ChemIDplus PA-94 ChemIDplus Ro-1-9213 ChemIDplus Seromycin ChemIDplus alpha-Cycloserine NIST_Chemistry_WebBook cicloserina ChemIDplus cyclo-D-serine ChemIDplus cycloserine ChemIDplus cycloserine WHO_MedNet cycloserinum ChemIDplus orientomycin ChemIDplus A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. 0 C62H111N11O12 InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1 PMATZTZNYRCHOR-CGLBZJNRSA-N 1202.635 1201.84137 CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C CHEBI:63586 CHEBI:91802 Beilstein:3647785 CAS:59865-13-3 Chemspider:4447449 DrugBank:DB00091 Drug_Central:760 HMDB:HMDB0250682 KEGG:C05086 KEGG:D00184 KNApSAcK:C00001517 LINCS:LSM-1703 LIPID_MAPS_instance:LMPK14000003 MetaCyc:CPD-20532 PMID:11058832 PMID:11069928 PMID:11079273 PMID:11080188 PMID:11238591 PMID:11256490 PMID:11278005 PMID:11315347 PMID:11370709 PMID:11406057 PMID:11426833 PMID:11442023 PMID:11481617 PMID:11493684 PMID:11529914 PMID:11557554 PMID:11564166 PMID:11676831 PMID:11870366 PMID:12021257 PMID:12050171 PMID:12603598 PMID:12761440 PMID:12929192 PMID:12950728 PMID:14521916 PMID:14621732 PMID:14638917 PMID:14672695 PMID:14682659 PMID:14743390 PMID:15030555 PMID:15175101 PMID:15210365 PMID:15306697 PMID:15383526 PMID:15541012 PMID:15613074 PMID:15626898 PMID:15657176 PMID:1566062 PMID:15711594 PMID:15811524 PMID:15962181 PMID:16372476 PMID:16404634 PMID:16724420 PMID:16801218 PMID:16898534 PMID:17032751 PMID:17083576 PMID:17117422 PMID:17192032 PMID:17220244 PMID:17229932 PMID:17265451 PMID:17446460 PMID:17603747 PMID:18076075 PMID:18171316 PMID:18191430 PMID:18217899 PMID:18259730 PMID:18299432 PMID:18359899 PMID:18583716 PMID:18597363 PMID:18790203 PMID:18818682 PMID:18931077 PMID:18975184 PMID:19282398 PMID:19589783 PMID:21752960 PMID:23620378 PMID:24134630 PMID:31144214 PMID:34561200 PMID:34561814 Patent:US4117118 Reaxys:3647785 VSDB:1765 Wikipedia:Ciclosporin 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone Cyclosporin A cyclosporin A chebi_ontology (R-[R*,R*-(E)])-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl) 1,11-cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(E)-(2S,3R,4R)-2-amino-3-hydroxy-N,4-dimethyloct-6-enoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine] 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone Antibiotic S 7481F1 Ciclosporin Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl)-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl) Cyclosporine Gengraf Neoral Sandimmune ciclosporin ciclosporina ciclosporine ciclosporinum CHEBI:4031 cyclosporin A CHEBI:4031 Beilstein:3647785 Beilstein CAS:59865-13-3 ChemIDplus CAS:59865-13-3 KEGG COMPOUND Drug_Central:760 DrugCentral LIPID_MAPS_instance:LMPK14000003 LIPID MAPS PMID:11058832 Europe PMC PMID:11069928 Europe PMC PMID:11079273 Europe PMC PMID:11080188 Europe PMC PMID:11238591 Europe PMC PMID:11256490 Europe PMC PMID:11278005 Europe PMC PMID:11315347 Europe PMC PMID:11370709 Europe PMC PMID:11406057 Europe PMC PMID:11426833 Europe PMC PMID:11442023 Europe PMC PMID:11481617 Europe PMC PMID:11493684 Europe PMC PMID:11529914 Europe PMC PMID:11557554 Europe PMC PMID:11564166 Europe PMC PMID:11676831 Europe PMC PMID:11870366 Europe PMC PMID:12021257 Europe PMC PMID:12050171 Europe PMC PMID:12603598 Europe PMC PMID:12761440 Europe PMC PMID:12929192 Europe PMC PMID:12950728 Europe PMC PMID:14521916 Europe PMC PMID:14621732 Europe PMC PMID:14638917 Europe PMC PMID:14672695 Europe PMC PMID:14682659 Europe PMC PMID:14743390 Europe PMC PMID:15030555 Europe PMC PMID:15175101 Europe PMC PMID:15210365 Europe PMC PMID:15306697 Europe PMC PMID:15383526 Europe PMC PMID:15541012 Europe PMC PMID:15613074 Europe PMC PMID:15626898 Europe PMC PMID:15657176 Europe PMC PMID:1566062 Europe PMC PMID:15711594 Europe PMC PMID:15811524 Europe PMC PMID:15962181 Europe PMC PMID:16372476 Europe PMC PMID:16404634 Europe PMC PMID:16724420 Europe PMC PMID:16801218 Europe PMC PMID:16898534 Europe PMC PMID:17032751 Europe PMC PMID:17083576 Europe PMC PMID:17117422 Europe PMC PMID:17192032 Europe PMC PMID:17220244 Europe PMC PMID:17229932 Europe PMC PMID:17265451 Europe PMC PMID:17446460 Europe PMC PMID:17603747 Europe PMC PMID:18076075 Europe PMC PMID:18171316 Europe PMC PMID:18191430 Europe PMC PMID:18217899 Europe PMC PMID:18259730 Europe PMC PMID:18299432 Europe PMC PMID:18359899 Europe PMC PMID:18583716 Europe PMC PMID:18597363 Europe PMC PMID:18790203 Europe PMC PMID:18818682 Europe PMC PMID:18931077 Europe PMC PMID:18975184 Europe PMC PMID:19282398 Europe PMC PMID:19589783 Europe PMC PMID:21752960 Europe PMC PMID:23620378 Europe PMC PMID:24134630 Europe PMC PMID:31144214 Europe PMC PMID:34561200 Europe PMC PMID:34561814 Europe PMC Reaxys:3647785 Reaxys 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone IUPAC Cyclosporin A KEGG_COMPOUND cyclosporin A UniProt (R-[R*,R*-(E)])-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl) ChEBI 1,11-cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(E)-(2S,3R,4R)-2-amino-3-hydroxy-N,4-dimethyloct-6-enoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine] JCBN 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone ChEBI Antibiotic S 7481F1 ChemIDplus Ciclosporin KEGG_COMPOUND Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl)-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl) ChemIDplus Cyclosporine ChemIDplus Cyclosporine KEGG_COMPOUND Gengraf DrugBank Neoral DrugBank Sandimmune DrugBank ciclosporin KEGG_DRUG ciclosporina ChemIDplus ciclosporine ChemIDplus ciclosporinum ChemIDplus Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. 0 C22H25N3O7S InChI=1S/C22H25N3O7S/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32)/t9-,10-,13+,14+,15-,16-/m1/s1 JUZNIMUFDBIJCM-ANEDZVCMSA-N 475.51500 475.14132 [H][C@]1(CN[C@@]([H])(C1)C(=O)Nc1cccc(c1)C(O)=O)SC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])[C@H]1C)C(O)=O CHEBI:471574 Beilstein:9025520 CAS:153832-46-3 DrugBank:DB00303 Drug_Central:1046 KEGG:D07908 Patent:US5478820 Patent:WO9315078 Wikipedia:Ertapenem (4R,5S,6S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ERTAPENEM chebi_ontology (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ertapenem CHEBI:404903 ertapenem CHEBI:404903 Beilstein:9025520 Beilstein CAS:153832-46-3 ChemIDplus CAS:153832-46-3 KEGG DRUG Drug_Central:1046 DrugCentral (4R,5S,6S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid IUPAC ERTAPENEM ChEMBL (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ChEBI (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ChEMBL ertapenem KEGG_DRUG An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture. 0 C22H17N3O5 InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+ WFDXOXNFNRHQEC-GHRIWEEISA-N 403.38750 403.11682 CO\C=C(\C(=O)OC)c1ccccc1Oc1cc(Oc2ccccc2C#N)ncn1 Beilstein:8350244 CAS:131860-33-8 KEGG:C18558 PDBeChem:AZO PMID:20818521 PMID:21153804 PMID:21671616 PMID:21777591 PMID:21884765 PMID:22092932 PMID:22224459 PMID:22278367 PMID:24125711 PMID:24405376 PMID:24700092 PMID:24726979 PMID:25011117 PMID:25090100 PMID:25196149 PPDB:54 Patent:EP382375 Patent:US5395837 Pesticides:azoxystrobin Reaxys:8350244 Wikipedia:Azoxystrobin methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoate chebi_ontology (alphaE)-2-[[6-(2-cyanophenoxy)-4-pyrimidinyl]oxy]-alpha-(methoxymethylene) benzeneacetic acid methyl ester methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl]-3-methoxyacrylate CHEBI:40909 azoxystrobin CHEBI:40909 Beilstein:8350244 Beilstein CAS:131860-33-8 ChemIDplus CAS:131860-33-8 KEGG COMPOUND PMID:20818521 Europe PMC PMID:21153804 Europe PMC PMID:21671616 Europe PMC PMID:21777591 Europe PMC PMID:21884765 Europe PMC PMID:22092932 Europe PMC PMID:22224459 Europe PMC PMID:22278367 Europe PMC PMID:24125711 Europe PMC PMID:24405376 Europe PMC PMID:24700092 Europe PMC PMID:24726979 Europe PMC PMID:25011117 Europe PMC PMID:25090100 Europe PMC PMID:25196149 Europe PMC Pesticides:azoxystrobin Alan Wood's Pesticides Reaxys:8350244 Reaxys methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoate IUPAC (alphaE)-2-[[6-(2-cyanophenoxy)-4-pyrimidinyl]oxy]-alpha-(methoxymethylene) benzeneacetic acid methyl ester ChEBI methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl]-3-methoxyacrylate ChEBI chebi_ontology CHEBI:41032 5-methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazol-1-ium CHEBI:41032 The 1H-tautomer of benzimidazole. 0 C7H6N2 InChI=1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-5H,(H,8,9) HYZJCKYKOHLVJF-UHFFFAOYSA-N 118.13602 118.05310 c1ccc2[nH]cnc2c1 CHEBI:3028 CHEBI:41272 Beilstein:109682 CAS:51-17-2 DrugBank:DB02962 Gmelin:3106 KEGG:C02009 MetaCyc:BENZIMIDAZOLE PDBeChem:BZI PMID:24152176 PMID:8070089 Reaxys:109682 Wikipedia:Benzimidazole 1H-benzimidazole chebi_ontology 1,3-benzodiazole 1,3-diazaindene BENZIMIDAZOLE Benzimidazole Hbim Hbzim azindole benzimidazole benzoglyoxaline o-benzimidazole CHEBI:41275 1H-benzimidazole CHEBI:41275 Beilstein:109682 Beilstein CAS:51-17-2 ChemIDplus CAS:51-17-2 KEGG COMPOUND CAS:51-17-2 NIST Chemistry WebBook Gmelin:3106 Gmelin PMID:24152176 Europe PMC PMID:8070089 Europe PMC Reaxys:109682 Reaxys 1H-benzimidazole IUPAC 1,3-benzodiazole ChemIDplus 1,3-diazaindene ChemIDplus BENZIMIDAZOLE PDBeChem Benzimidazole KEGG_COMPOUND Hbim IUPAC Hbzim IUPAC azindole ChemIDplus benzimidazole IUPAC benzoglyoxaline ChemIDplus o-benzimidazole NIST_Chemistry_WebBook -2 CO3 InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2 BVKZGUZCCUSVTD-UHFFFAOYSA-L 60.00890 59.98584 [O-]C([O-])=O CHEBI:29201 CHEBI:41605 Beilstein:3600898 CAS:3812-32-6 Gmelin:1559 PDBeChem:CO3 carbonate trioxidocarbonate(2-) chebi_ontology CARBONATE ION CO3(2-) Karbonat [CO3](2-) CHEBI:41609 carbonate CHEBI:41609 Beilstein:3600898 Beilstein CAS:3812-32-6 ChemIDplus Gmelin:1559 Gmelin carbonate IUPAC trioxidocarbonate(2-) IUPAC CARBONATE ION PDBeChem CO3(2-) ChEBI Karbonat ChEBI [CO3](2-) IUPAC A glucopyranose having D-configuration. 0 C6H12O6 InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1 WQZGKKKJIJFFOK-GASJEMHNSA-N 180.15588 180.06339 OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Beilstein:1281604 CAS:2280-44-6 GlyGen:G15021LG GlyTouCan:G15021LG Gmelin:83256 HMDB:HMDB0000122 KEGG:C00031 KEGG:D00009 KNApSAcK:C00001122 MetaCyc:D-Glucose PMID:15987845 PMID:16901854 PMID:17336832 PMID:17439666 PMID:17928662 PMID:19913595 PMID:26812026 PMID:32619908 PMID:7524207 PMID:9140037 PMID:9501190 PMID:9506998 PMID:9545565 Reaxys:1281604 Wikipedia:Glucose D-glucopyranose chebi_ontology D-Glc D-Glcp D-Glucose D-glucose Dextrose Glc-OH Glucose Grape sugar WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/ glucose CHEBI:4167 D-glucopyranose CHEBI:4167 Beilstein:1281604 Beilstein CAS:2280-44-6 ChemIDplus Gmelin:83256 Gmelin PMID:15987845 Europe PMC PMID:16901854 Europe PMC PMID:17336832 Europe PMC PMID:17439666 Europe PMC PMID:17928662 Europe PMC PMID:19913595 Europe PMC PMID:26812026 Europe PMC PMID:32619908 Europe PMC PMID:7524207 Europe PMC PMID:9140037 Europe PMC PMID:9501190 Europe PMC PMID:9506998 Europe PMC PMID:9545565 Europe PMC Reaxys:1281604 Reaxys D-glucopyranose IUPAC D-Glc ChEBI D-Glcp ChEBI D-Glucose KEGG_COMPOUND D-glucose UniProt Dextrose KEGG_COMPOUND Glc-OH ChEBI Glucose KEGG_COMPOUND Grape sugar KEGG_COMPOUND WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/ GlyTouCan glucose ChEBI chebi_ontology CHEBI:417636 4-{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl}-thiazol-2-yl-ammonium CHEBI:417636 A hexose that has D-configuration at position 5. 0 C6H12O6 180.156 180.06339 KEGG:C00738 D-Hexose D-hexopyranose chebi_ontology D-hexoses a D-hexose CHEBI:4194 D-hexose CHEBI:4194 D-Hexose KEGG_COMPOUND D-hexopyranose IUPAC D-hexoses ChEBI a D-hexose UniProt A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2. 0 C6H12F2N2O2 InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12) VLCYCQAOQCDTCN-UHFFFAOYSA-N 182.16850 182.08668 NCCCC(N)(C(F)F)C(O)=O CHEBI:41946 CHEBI:4761 Beilstein:2250529 CAS:67037-37-0 CAS:70052-12-9 DrugBank:DB03856 Drug_Central:990 KEGG:C07997 KEGG:D07883 PDBeChem:DMO PMID:16541214 PMID:23771434 PMID:24144414 Reaxys:2250529 Wikipedia:Eflornithine 2,5-diamino-2-(difluoromethyl)pentanoic acid 2-(difluoromethyl)ornithine Eflornithine chebi_ontology ALPHA-DIFLUOROMETHYLORNITHINE DFMO DL-Ornithine, 2-(difluoromethyl)- alpha-(Difluoromethyl)-DL-ornithine alpha-difluoromethylornithine CHEBI:41948 eflornithine CHEBI:41948 Beilstein:2250529 ChemIDplus CAS:67037-37-0 ChemIDplus CAS:67037-37-0 KEGG COMPOUND CAS:70052-12-9 ChemIDplus Drug_Central:990 DrugCentral PMID:16541214 Europe PMC PMID:23771434 Europe PMC PMID:24144414 Europe PMC Reaxys:2250529 Reaxys 2,5-diamino-2-(difluoromethyl)pentanoic acid IUPAC 2-(difluoromethyl)ornithine IUPAC Eflornithine KEGG_COMPOUND ALPHA-DIFLUOROMETHYLORNITHINE PDBeChem DFMO ChemIDplus DL-Ornithine, 2-(difluoromethyl)- KEGG_COMPOUND alpha-(Difluoromethyl)-DL-ornithine DrugCentral alpha-difluoromethylornithine ChemIDplus An alkane comprising of two carbon atoms. 0 C2H6 InChI=1S/C2H6/c1-2/h1-2H3 OTMSDBZUPAUEDD-UHFFFAOYSA-N 30.06904 30.04695 CC CHEBI:23975 CHEBI:42260 Beilstein:1730716 CAS:74-84-0 Gmelin:212 PMID:12826252 PMID:14664856 PMID:16236899 Reaxys:1730716 Wikipedia:Ethane ETHANE ethane chebi_ontology Aethan C2H6 CH3-CH3 Ethan R-170 bimethyl dimethyl ethyl hydride methylmethane CHEBI:42266 ethane CHEBI:42266 Beilstein:1730716 Beilstein CAS:74-84-0 ChemIDplus CAS:74-84-0 NIST Chemistry WebBook Gmelin:212 Gmelin PMID:12826252 Europe PMC PMID:14664856 Europe PMC PMID:16236899 Europe PMC Reaxys:1730716 Reaxys ETHANE PDBeChem ethane IUPAC Aethan ChEBI C2H6 ChEBI CH3-CH3 IUPAC Ethan ChEBI R-170 ChEBI bimethyl NIST_Chemistry_WebBook dimethyl NIST_Chemistry_WebBook ethyl hydride NIST_Chemistry_WebBook methylmethane NIST_Chemistry_WebBook An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. 0 C37H67NO13 InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 733.92680 733.46124 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O CHEBI:112506 CHEBI:23950 CHEBI:28672 CHEBI:42352 CHEBI:4841 CHEBI:4843 Beilstein:75000 Beilstein:75279 CAS:114-07-8 CAS:1675-02-1 DrugBank:DB00199 Drug_Central:1048 KEGG:C01912 KEGG:D00140 LINCS:LSM-3416 LIPID_MAPS_instance:LMPK04000006 MetaCyc:CPD-13804 PDBeChem:ERY Patent:US2823203 Reaxys:75279 (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-14-ethyl-7,12,13-trihydroxy-6-[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyloxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione ERYTHROMYCIN A Erythromycin A erythromycin chebi_ontology (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 3''-O-demethylerythromycin Abomacetin ERYTHROMYCIN Erythromycin Erythromycin C eritromicina erthromycin erythromycin erythromycine erythromycinum CHEBI:42355 erythromycin A CHEBI:42355 Beilstein:75000 Beilstein Beilstein:75279 Beilstein CAS:114-07-8 ChemIDplus CAS:114-07-8 KEGG COMPOUND CAS:1675-02-1 ChemIDplus Drug_Central:1048 DrugCentral LIPID_MAPS_instance:LMPK04000006 LIPID MAPS Reaxys:75279 Reaxys (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-14-ethyl-7,12,13-trihydroxy-6-[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyloxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione IUPAC ERYTHROMYCIN A PDBeChem Erythromycin A ChEMBL Erythromycin A KEGG_COMPOUND erythromycin IUPAC (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione IUPAC 3''-O-demethylerythromycin ChemIDplus Abomacetin KEGG_COMPOUND ERYTHROMYCIN ChEMBL Erythromycin ChEMBL Erythromycin KEGG_COMPOUND Erythromycin C KEGG_COMPOUND eritromicina ChemIDplus erthromycin ChEBI erythromycin ChemIDplus erythromycine ChemIDplus erythromycinum ChemIDplus 0 CHO 29.01804 29.00274 [H]C(*)=O CHEBI:24089 CHEBI:42480 PDBeChem:FOR FORMYL GROUP aldehyde group carbaldehyde formyl chebi_ontology -CH(O) -CHO Fo H-CO- methanoyl CHEBI:42485 formyl group CHEBI:42485 FORMYL GROUP PDBeChem aldehyde group IUPAC carbaldehyde IUPAC formyl IUPAC -CH(O) IUPAC -CHO IUPAC Fo CBN H-CO- IUPAC methanoyl IUPAC 0 HO 17.00734 17.00274 *O[H] CHEBI:24706 CHEBI:43171 PDBeChem:OH HYDROXY GROUP hydroxy hydroxy group chebi_ontology -OH hydroxyl hydroxyl group CHEBI:43176 hydroxy group CHEBI:43176 HYDROXY GROUP PDBeChem hydroxy IUPAC hydroxy group UniProt -OH IUPAC hydroxyl ChEBI hydroxyl group ChEBI chebi_ontology CHEBI:43254 (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one CHEBI:43254 A phosphate ion that is the conjugate base of dihydrogenphosphate. -2 HO4P InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2 NBIIXXVUZAFLBC-UHFFFAOYSA-L 95.97930 95.96234 OP([O-])([O-])=O CHEBI:29139 CHEBI:43470 Gmelin:1998 MolBase:1628 PDBeChem:PI PDBeChem:PO4 hydrogen(tetraoxidophosphate)(2-) hydrogenphosphate hydrogentetraoxophosphate(2-) hydrogentetraoxophosphate(V) hydroxidotrioxidophosphate(2-) chebi_ontology HPO4(2-) HYDROGENPHOSPHATE ION INORGANIC PHOSPHATE GROUP [P(OH)O3](2-) [PO3(OH)](2-) hydrogen phosphate phosphate CHEBI:43474 hydrogenphosphate CHEBI:43474 Gmelin:1998 Gmelin hydrogen(tetraoxidophosphate)(2-) IUPAC hydrogenphosphate IUPAC hydrogentetraoxophosphate(2-) IUPAC hydrogentetraoxophosphate(V) IUPAC hydroxidotrioxidophosphate(2-) IUPAC HPO4(2-) IUPAC HYDROGENPHOSPHATE ION PDBeChem INORGANIC PHOSPHATE GROUP PDBeChem [P(OH)O3](2-) MolBase [PO3(OH)](2-) IUPAC hydrogen phosphate ChEBI phosphate UniProt A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. 0 C17H25N3O5S InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1 DMJNNHOOLUXYBV-PQTSNVLCSA-N 383.46300 383.15149 [H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O Beilstein:6826115 CAS:96036-03-2 DrugBank:DB00760 Drug_Central:1709 LINCS:LSM-5208 PDBeChem:MER PMID:10776838 PMID:11069213 PMID:18611786 PMID:18645546 PMID:28343819 PMID:28371721 PMID:28583381 PMID:28669829 PMID:28677407 PMID:7588092 Patent:EP126587 Patent:US4943569 Wikipedia:Meropenem (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid Meropenem chebi_ontology (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Antibiotic SM 7338 MEPM meropenem meropenem anhydrous meropenemum CHEBI:43968 meropenem CHEBI:43968 Beilstein:6826115 Beilstein CAS:96036-03-2 ChemIDplus Drug_Central:1709 DrugCentral PMID:10776838 Europe PMC PMID:11069213 Europe PMC PMID:18611786 Europe PMC PMID:18645546 Europe PMC PMID:28343819 Europe PMC PMID:28371721 Europe PMC PMID:28583381 Europe PMC PMID:28669829 Europe PMC PMID:28677407 Europe PMC PMID:7588092 Europe PMC (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid IUPAC Meropenem ChemIDplus (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID PDBeChem (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid IUPAC Antibiotic SM 7338 DrugBank MEPM ChEBI meropenem ChEBI meropenem anhydrous ChemIDplus meropenemum DrugBank A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae. 0 C28H47NO4S InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1 UURAUHCOJAIIRQ-QGLSALSOSA-N 493.74200 493.32258 CCN(CC)CCSCC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@H](C)[C@]23CCC(=O)[C@H]2[C@@]1(C)[C@H](C)CC3 CHEBI:29695 CAS:55297-95-5 KEGG:C12065 KEGG:D06127 PDBeChem:MUL PMID:15013817 PMID:16253666 PMID:25592328 PMID:3170319 PMID:3686511 Patent:DE2248237 Patent:US3919290 Reaxys:7348837 Wikipedia:Tiamulin (3aS,4R,5S,6S,8R,9R,9aR,10R)-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate chebi_ontology tiamulin tiamulina tiamuline tiamulinum CHEBI:44137 tiamulin CHEBI:44137 CAS:55297-95-5 ChemIDplus CAS:55297-95-5 KEGG COMPOUND PMID:15013817 Europe PMC PMID:16253666 Europe PMC PMID:25592328 Europe PMC PMID:3170319 Europe PMC PMID:3686511 Europe PMC Reaxys:7348837 Reaxys (3aS,4R,5S,6S,8R,9R,9aR,10R)-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate IUPAC tiamulin WHO_MedNet tiamulina WHO_MedNet tiamuline WHO_MedNet tiamulinum WHO_MedNet A phosphorus oxoacid that consists of a single pentavalent phosphorus covalently bound via single bonds to a single hydrogen and two hydroxy groups and via a double bond to an oxygen. The parent of the class of phosphonic acids. 0 H3O3P InChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3) ABLZXFCXXLZCGV-UHFFFAOYSA-N 81.99580 81.98198 OP(O)=O CHEBI:26067 CAS:13598-36-2 Gmelin:1619 KEGG:C06701 PDBeChem:PHS Reaxys:1209272 Wikipedia:Phosphonic_acid Phosphonic acid dihydrogen hydridotrioxophosphate(2-) hydridodihydroxidooxidophosphorus hydridotrioxophosphoric(2-) acid phosphonic acid chebi_ontology (HO)2HPO H2PHO3 H3PO3 HPO(OH)2 Phosphite Phosphonate Phosphonsaeure [PHO(OH)2] CHEBI:44976 phosphonic acid CHEBI:44976 CAS:13598-36-2 ChemIDplus CAS:13598-36-2 KEGG COMPOUND CAS:13598-36-2 NIST Chemistry WebBook Gmelin:1619 Gmelin Reaxys:1209272 Reaxys Phosphonic acid KEGG_COMPOUND dihydrogen hydridotrioxophosphate(2-) IUPAC hydridodihydroxidooxidophosphorus IUPAC hydridotrioxophosphoric(2-) acid IUPAC phosphonic acid ChEBI (HO)2HPO NIST_Chemistry_WebBook H2PHO3 IUPAC H3PO3 ChEBI HPO(OH)2 IUPAC Phosphite KEGG_COMPOUND Phosphonate KEGG_COMPOUND Phosphonsaeure ChEBI [PHO(OH)2] IUPAC A trivalent inorganic anion obtained by removal of all three protons from phosphorous acid. -3 O3P InChI=1S/O3P/c1-4(2)3/q-3 AQSJGOWTSHOLKH-UHFFFAOYSA-N 78.97196 78.96015 [O-]P([O-])[O-] CHEBI:29197 CHEBI:45060 Gmelin:68617 PDBeChem:PO3 trioxidophosphate(3-) trioxophosphate(3-) trioxophosphate(III) chebi_ontology PHOSPHITE ION PO3(3-) Phosphit [PO3](3-) phosphite CHEBI:45064 phosphite(3-) CHEBI:45064 Gmelin:68617 Gmelin trioxidophosphate(3-) IUPAC trioxophosphate(3-) IUPAC trioxophosphate(III) IUPAC PHOSPHITE ION PDBeChem PO3(3-) IUPAC Phosphit ChEBI [PO3](3-) IUPAC phosphite IUPAC A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. 0 C19H24N4O2 InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23) XDRYMKDFEDOLFX-UHFFFAOYSA-N 340.420 340.18993 C(CCCOC1=CC=C(C=C1)C(N)=N)COC2=CC=C(C=C2)C(N)=N CHEBI:45077 CHEBI:7976 Beilstein:3159790 CAS:100-33-4 DrugBank:DB00738 Drug_Central:2090 HMDB:HMDB0014876 KEGG:C07420 KEGG:D08333 LINCS:LSM-4540 PDBeChem:PNT PMID:10415905 PMID:10917591 PMID:11438428 PMID:11584934 PMID:14603035 PMID:15711592 PMID:18346045 PMID:18971316 PMID:19966562 PMID:20144237 PMID:20599360 PMID:22046004 PMID:22093811 PMID:22200378 PMID:22327112 PMID:26052915 PMID:26117647 PMID:26295040 PMID:26344166 PMID:26418240 PMID:26431253 PMID:26515653 PMID:26606757 PMID:26648589 PMID:26734860 PMID:26824946 PMID:26828608 PMID:26882015 PMID:26903605 PMID:26938448 PMID:27011917 PMID:27135970 PMID:27164533 PMID:27214074 PMID:27297108 PMID:27353022 PMID:27357655 PMID:27600039 PMID:27729250 PMID:28074607 PMID:28167598 PMID:28263303 PMID:7542607 PMID:7690919 PMID:8841838 Patent:EP975608 Patent:GB507565 Patent:US2006235001 Patent:US2008167296 Patent:US2008214569 Patent:US2394003 Patent:US7115665 Reaxys:3159790 Wikipedia:Pentamidine 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide Pentamidine chebi_ontology 1,5-bis(4-amidinophenoxy)pentane 4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide 4,4'-(pentamethylenedioxy)dibenzamidine 4,4'-Diamidinodiphenoxypentane p,p'-(pentamethylenedioxy)dibenzamidine pentamidin pentamidine CHEBI:45081 pentamidine CHEBI:45081 Beilstein:3159790 ChemIDplus CAS:100-33-4 ChemIDplus CAS:100-33-4 KEGG COMPOUND Drug_Central:2090 DrugCentral PMID:10415905 Europe PMC PMID:10917591 Europe PMC PMID:11438428 Europe PMC PMID:11584934 Europe PMC PMID:14603035 Europe PMC PMID:15711592 Europe PMC PMID:18346045 Europe PMC PMID:18971316 Europe PMC PMID:19966562 Europe PMC PMID:20144237 Europe PMC PMID:20599360 Europe PMC PMID:22046004 Europe PMC PMID:22093811 Europe PMC PMID:22200378 Europe PMC PMID:22327112 Europe PMC PMID:26052915 Europe PMC PMID:26117647 Europe PMC PMID:26295040 Europe PMC PMID:26344166 Europe PMC PMID:26418240 Europe PMC PMID:26431253 Europe PMC PMID:26515653 Europe PMC PMID:26606757 Europe PMC PMID:26648589 Europe PMC PMID:26734860 Europe PMC PMID:26824946 Europe PMC PMID:26828608 Europe PMC PMID:26882015 Europe PMC PMID:26903605 Europe PMC PMID:26938448 Europe PMC PMID:27011917 Europe PMC PMID:27135970 Europe PMC PMID:27164533 Europe PMC PMID:27214074 Europe PMC PMID:27297108 Europe PMC PMID:27353022 Europe PMC PMID:27357655 Europe PMC PMID:27600039 Europe PMC PMID:27729250 Europe PMC PMID:28074607 Europe PMC PMID:28167598 Europe PMC PMID:28263303 Europe PMC PMID:7542607 Europe PMC PMID:7690919 Europe PMC PMID:8841838 Europe PMC Reaxys:3159790 Reaxys 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide IUPAC Pentamidine KEGG_COMPOUND 1,5-bis(4-amidinophenoxy)pentane ChEBI 4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide ChemIDplus 4,4'-(pentamethylenedioxy)dibenzamidine ChemIDplus 4,4'-Diamidinodiphenoxypentane DrugBank p,p'-(pentamethylenedioxy)dibenzamidine ChemIDplus pentamidin DrugCentral pentamidine KEGG_DRUG A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. 0 C19H17Cl2N3O5S InChI=1S/C19H17Cl2N3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1 YFAGHNZHGGCZAX-JKIFEVAISA-N 470.32600 469.02660 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1c(Cl)cccc1Cl)C(O)=O Beilstein:1233662 CAS:3116-76-5 DrugBank:DB00485 Drug_Central:866 KEGG:C06950 KEGG:D02348 LINCS:LSM-5234 PMID:26962156 PMID:28721014 PMID:29017833 PMID:29105855 PMID:29253094 PMID:29504695 Patent:GB978299 Patent:US3239507 Reaxys:1233662 Wikipedia:Dicloxacillin 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylic acid Dicloxacillin chebi_ontology (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid dicloxacilina dicloxacilline dicloxacillinum CHEBI:4511 dicloxacillin CHEBI:4511 Beilstein:1233662 Beilstein CAS:3116-76-5 KEGG COMPOUND Drug_Central:866 DrugCentral PMID:26962156 Europe PMC PMID:28721014 Europe PMC PMID:29017833 Europe PMC PMID:29105855 Europe PMC PMID:29253094 Europe PMC PMID:29504695 Europe PMC Reaxys:1233662 Reaxys 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC Dicloxacillin KEGG_COMPOUND (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC dicloxacilina DrugBank dicloxacilline DrugBank dicloxacillinum DrugBank A carbamate ester that is the isopropyl ester of (3,4-diethoxyphenyl)carbamic acid. A fungicide with strong activity against Botrytis cinerea and benzimidazole-resistant strains of Botryis spp. 0 C14H21NO4 InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16) LNJNFVJKDJYTEU-UHFFFAOYSA-N 267.32080 267.14706 CCOc1ccc(NC(=O)OC(C)C)cc1OCC CAS:87130-20-9 KEGG:C11077 PMID:21174194 PMID:21763813 PMID:22921656 PMID:23404952 PMID:23597988 PMID:23760810 PMID:24679760 PMID:24817605 PMID:24861738 PMID:24973804 PPDB:228 Pesticides:diethofencarb Reaxys:8393454 propan-2-yl (3,4-diethoxyphenyl)carbamate chebi_ontology 1-Methylethyl (3,4-diethoxyphenyl)carbamate 1-methylethyl N-(3,4-diethoxyphenyl)carbamate Isopropyl 3,4-diethoxycarbanilate isopropyl (3,4-diethoxyphenyl)carbamate CHEBI:4520 diethofencarb CHEBI:4520 CAS:87130-20-9 ChemIDplus CAS:87130-20-9 KEGG COMPOUND CAS:87130-20-9 NIST Chemistry WebBook PMID:21174194 Europe PMC PMID:21763813 Europe PMC PMID:22921656 Europe PMC PMID:23404952 Europe PMC PMID:23597988 Europe PMC PMID:23760810 Europe PMC PMID:24679760 Europe PMC PMID:24817605 Europe PMC PMID:24861738 Europe PMC PMID:24973804 Europe PMC Pesticides:diethofencarb Alan Wood's Pesticides Reaxys:8393454 Reaxys propan-2-yl (3,4-diethoxyphenyl)carbamate IUPAC 1-Methylethyl (3,4-diethoxyphenyl)carbamate ChemIDplus 1-methylethyl N-(3,4-diethoxyphenyl)carbamate Alan_Wood's_Pesticides Isopropyl 3,4-diethoxycarbanilate ChemIDplus isopropyl (3,4-diethoxyphenyl)carbamate IUPAC A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis. 0 C5H5N3O InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9) IPEHBUMCGVEMRF-UHFFFAOYSA-N 123.11282 123.04326 NC(=O)c1cnccn1 CHEBI:45281 CHEBI:8656 Beilstein:112306 CAS:98-96-4 DrugBank:DB00339 Drug_Central:2328 Gmelin:279021 HMDB:HMDB0014483 KEGG:C01956 KEGG:D00144 LINCS:LSM-5425 PDBeChem:PZA PMID:14977529 PMID:18517115 PMID:18604033 Reaxys:112306 Wikipedia:Pyrazinamide pyrazine-2-carboxamide chebi_ontology 2-carbamylpyrazine 2-pyrazinecarboxamide PYRAZINE-2-CARBOXAMIDE Pyrazinamide Pyrazinoic acid amide pyrazinamida pyrazinamide pyrazinamidum pyrazine carboxamide pyrazineamide CHEBI:45285 pyrazinecarboxamide CHEBI:45285 Beilstein:112306 Beilstein CAS:98-96-4 ChemIDplus CAS:98-96-4 KEGG COMPOUND CAS:98-96-4 NIST Chemistry WebBook Drug_Central:2328 DrugCentral Gmelin:279021 Gmelin PMID:14977529 Europe PMC PMID:18517115 Europe PMC PMID:18604033 Europe PMC Reaxys:112306 Reaxys pyrazine-2-carboxamide IUPAC 2-carbamylpyrazine ChemIDplus 2-pyrazinecarboxamide ChemIDplus PYRAZINE-2-CARBOXAMIDE PDBeChem Pyrazinamide KEGG_COMPOUND Pyrazinoic acid amide KEGG_COMPOUND pyrazinamida WHO_MedNet pyrazinamide UniProt pyrazinamide WHO_MedNet pyrazinamidum WHO_MedNet pyrazine carboxamide NIST_Chemistry_WebBook pyrazineamide NIST_Chemistry_WebBook 0 C46H62N4O11 InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1 ATEBXHFBFRCZMA-VXTBVIBXSA-N 847.00484 846.44151 CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC5)CC(C)C)N=C1c4c3C2=O CHEBI:45364 CHEBI:8857 CAS:72559-06-9 DrugBank:DB00615 Drug_Central:2376 KEGG:C07235 KEGG:D00424 KNApSAcK:C00027872 Wikipedia:Rifabutin Rifabutin chebi_ontology 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S 4-N-isobutylspiropiperidylrifamycin S Mycobutin (TN) CHEBI:45367 rifabutin CHEBI:45367 CAS:72559-06-9 ChemIDplus CAS:72559-06-9 KEGG COMPOUND Drug_Central:2376 DrugCentral Rifabutin KEGG_COMPOUND Rifabutin KEGG_DRUG 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV ChemIDplus 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S ChemIDplus 4-N-isobutylspiropiperidylrifamycin S ChemIDplus Mycobutin (TN) KEGG_DRUG A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. 0 C6H8N2O2S InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) FDDDEECHVMSUSB-UHFFFAOYSA-N 172.20600 172.03065 Nc1ccc(cc1)S(N)(=O)=O CHEBI:45370 CHEBI:9333 Beilstein:511852 CAS:63-74-1 DrugBank:DB00259 Drug_Central:2521 Gmelin:83068 HMDB:HMDB0014404 KEGG:C07458 KEGG:D08543 LINCS:LSM-6524 PDBeChem:SAN PMID:22214209 PMID:22342371 PMID:22974493 PMID:23061287 PMID:23065453 PMID:23122138 PMID:23294218 PMID:23476893 PMID:23561569 PMID:2420897 PMID:9639594 Reaxys:511852 VSDB:1924 Wikipedia:Sulfanilamide 4-aminobenzenesulfonamide SULFANILAMIDE Sulfanilamide chebi_ontology 4-aminobenzene sulfonic acid amide 4-azanylbenzenesulfonamide Prontosil album SA Streptocide Sulfamine p-aminobenzenesulfamide p-aminobenzenesulfonamide para-aminobenzenesulfonamide sulfamine sulphanilamide CHEBI:45373 sulfanilamide CHEBI:45373 Beilstein:511852 Beilstein CAS:63-74-1 ChemIDplus CAS:63-74-1 KEGG COMPOUND CAS:63-74-1 NIST Chemistry WebBook Drug_Central:2521 DrugCentral Gmelin:83068 Gmelin PMID:22214209 Europe PMC PMID:22342371 Europe PMC PMID:22974493 Europe PMC PMID:23061287 Europe PMC PMID:23065453 Europe PMC PMID:23122138 Europe PMC PMID:23294218 Europe PMC PMID:23476893 Europe PMC PMID:23561569 Europe PMC PMID:2420897 Europe PMC PMID:9639594 Europe PMC Reaxys:511852 Reaxys 4-aminobenzenesulfonamide IUPAC SULFANILAMIDE PDBeChem Sulfanilamide KEGG_COMPOUND 4-aminobenzene sulfonic acid amide ChEBI 4-azanylbenzenesulfonamide IUPAC Prontosil album KEGG_COMPOUND SA ChEBI Streptocide NIST_Chemistry_WebBook Sulfamine KEGG_COMPOUND p-aminobenzenesulfamide NIST_Chemistry_WebBook p-aminobenzenesulfonamide NIST_Chemistry_WebBook para-aminobenzenesulfonamide ChEBI sulfamine NIST_Chemistry_WebBook sulphanilamide ChEBI 0 C12H26O4S InChI=1S/C12H26O4S/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H,13,14,15) MOTZDAYCYVMXPC-UHFFFAOYSA-N 266.39844 266.15518 CCCCCCCCCCCCOS(O)(=O)=O CHEBI:32953 CHEBI:45595 Beilstein:1710530 CAS:151-41-7 Gmelin:220505 PDBeChem:SDS dodecyl hydrogen sulfate chebi_ontology DODECYL SULFATE lauryl sulfuric acid monododecyl hydrogen sulfate sulfuric acid, monododecyl ester CHEBI:45599 dodecyl hydrogen sulfate CHEBI:45599 Beilstein:1710530 ChemIDplus CAS:151-41-7 ChemIDplus Gmelin:220505 Gmelin dodecyl hydrogen sulfate IUPAC DODECYL SULFATE PDBeChem lauryl sulfuric acid ChemIDplus monododecyl hydrogen sulfate ChemIDplus sulfuric acid, monododecyl ester ChemIDplus A hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2. 0 C7H7NO3 InChI=1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10) HBROZNQEVUILML-UHFFFAOYSA-N 153.13540 153.04259 ONC(=O)c1ccccc1O CHEBI:9007 CAS:89-73-6 DrugBank:DB03819 KEGG:C11343 MetaCyc:CPD-6543 PDBeChem:SHA PMID:16667326 PMID:1847381 PMID:22554042 PMID:23416493 PMID:24603484 PMID:24888389 PMID:2543361 Patent:CN101519365 Reaxys:1210520 Wikipedia:Salicylhydroxamic_acid N,2-dihydroxybenzamide chebi_ontology 2-Hydroxybenzhydroxamic acid 2-Hydroxybenzohydroxamic acid SHAM Salicylohydroximic acid o-Hydroxybenzohydroxamic acid CHEBI:45615 salicylhydroxamic acid CHEBI:45615 CAS:89-73-6 ChemIDplus CAS:89-73-6 KEGG COMPOUND PMID:16667326 Europe PMC PMID:1847381 Europe PMC PMID:22554042 Europe PMC PMID:23416493 Europe PMC PMID:24603484 Europe PMC PMID:24888389 Europe PMC PMID:2543361 Europe PMC Reaxys:1210520 Reaxys N,2-dihydroxybenzamide IUPAC 2-Hydroxybenzhydroxamic acid ChemIDplus 2-Hydroxybenzohydroxamic acid ChemIDplus SHAM ChEBI Salicylohydroximic acid ChemIDplus o-Hydroxybenzohydroxamic acid ChemIDplus -1 HO4S InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1 QAOWNCQODCNURD-UHFFFAOYSA-M 97.07154 96.96010 [H]OS([O-])(=O)=O CHEBI:29199 CHEBI:45693 Gmelin:2121 hydrogen(tetraoxidosulfate)(1-) hydrogensulfate hydrogensulfate(1-) hydrogentetraoxosulfate(1-) hydrogentetraoxosulfate(VI) hydroxidotrioxidosulfate(1-) chebi_ontology HSO4(-) HYDROGEN SULFATE [SO3(OH)](-) CHEBI:45696 hydrogensulfate CHEBI:45696 Gmelin:2121 Gmelin hydrogen(tetraoxidosulfate)(1-) IUPAC hydrogensulfate IUPAC hydrogensulfate(1-) IUPAC hydrogentetraoxosulfate(1-) IUPAC hydrogentetraoxosulfate(VI) IUPAC hydroxidotrioxidosulfate(1-) IUPAC HSO4(-) IUPAC HYDROGEN SULFATE PDBeChem [SO3(OH)](-) IUPAC An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge. 0 C14H18N4O3 InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18) IEDVJHCEMCRBQM-UHFFFAOYSA-N 290.318 290.13789 C=1(CC=2C(=NC(N)=NC2)N)C=C(C(OC)=C(C1)OC)OC CHEBI:45921 CHEBI:9731 Beilstein:625127 CAS:738-70-5 DrugBank:DB00440 Drug_Central:2755 Gmelin:808843 HMDB:HMDB0014583 KEGG:C01965 KEGG:D00145 LINCS:LSM-5246 PDBeChem:TOP PMID:10423629 PMID:10969053 PMID:11051625 PMID:14629008 PMID:15203044 PMID:16311012 PMID:18816075 PMID:25111783 PMID:25361939 PMID:26546758 PMID:26566149 PMID:26942256 PMID:26987772 PMID:28166217 PMID:7602118 PMID:8911701 Reaxys:625127 VSDB:1745 Wikipedia:Trimethoprim 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine TRIMETHOPRIM Trimethoprim chebi_ontology 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine Proloprim Trimpex CHEBI:45924 trimethoprim CHEBI:45924 Beilstein:625127 Beilstein CAS:738-70-5 ChemIDplus CAS:738-70-5 KEGG COMPOUND CAS:738-70-5 NIST Chemistry WebBook Drug_Central:2755 DrugCentral Gmelin:808843 Gmelin PMID:10423629 Europe PMC PMID:10969053 Europe PMC PMID:11051625 Europe PMC PMID:14629008 Europe PMC PMID:15203044 Europe PMC PMID:16311012 Europe PMC PMID:18816075 Europe PMC PMID:25111783 Europe PMC PMID:25361939 Europe PMC PMID:26546758 Europe PMC PMID:26566149 Europe PMC PMID:26942256 Europe PMC PMID:26987772 Europe PMC PMID:28166217 Europe PMC PMID:7602118 Europe PMC PMID:8911701 Europe PMC Reaxys:625127 Reaxys 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine IUPAC TRIMETHOPRIM PDBeChem Trimethoprim KEGG_COMPOUND 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine NIST_Chemistry_WebBook 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine NIST_Chemistry_WebBook Proloprim ChemIDplus Trimpex ChemIDplus A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. 0 C10H7N3S InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13) WJCNZQLZVWNLKY-UHFFFAOYSA-N 201.24800 201.03607 c1nc(cs1)-c1nc2ccccc2[nH]1 CHEBI:45977 CHEBI:9526 Beilstein:611403 CAS:148-79-8 DrugBank:DB00730 Drug_Central:2621 HMDB:HMDB0014868 KEGG:D00372 LINCS:LSM-3741 MetaCyc:THIABENDAZOLE PDBeChem:TMG PMID:11226373 PMID:13900465 PMID:23790859 PMID:9009055 PPDB:629 Patent:US3017415 Pesticides:thiabendazole Reaxys:611403 VSDB:629 Wikipedia:Thiabendazole 2-(1,3-thiazol-4-yl)-1H-benzimidazole Thiabendazole chebi_ontology 2-(1,3-THIAZOL-4-YL)-1H-BENZIMIDAZOLE 2-(1,3-thiazol-4-yl)benzimidazole 2-(4-thiazolyl)-1H-benzimidazole 2-(thiazol-4-yl)benzimidazole 4-(2-benzimidazolyl)thiazole Equizole MK 360 Mintezol TBZ Thibenzole Tiabendazole CHEBI:45979 thiabendazole CHEBI:45979 Beilstein:611403 Beilstein CAS:148-79-8 ChemIDplus CAS:148-79-8 NIST Chemistry WebBook Drug_Central:2621 DrugCentral PMID:11226373 Europe PMC PMID:13900465 Europe PMC PMID:23790859 Europe PMC PMID:9009055 Europe PMC Pesticides:thiabendazole Alan Wood's Pesticides Reaxys:611403 Reaxys 2-(1,3-thiazol-4-yl)-1H-benzimidazole IUPAC Thiabendazole KEGG_COMPOUND 2-(1,3-THIAZOL-4-YL)-1H-BENZIMIDAZOLE PDBeChem 2-(1,3-thiazol-4-yl)benzimidazole Alan_Wood's_Pesticides 2-(4-thiazolyl)-1H-benzimidazole Alan_Wood's_Pesticides 2-(thiazol-4-yl)benzimidazole Alan_Wood's_Pesticides 4-(2-benzimidazolyl)thiazole ChemIDplus Equizole ChemIDplus MK 360 ChemIDplus Mintezol KEGG_DRUG TBZ ChemIDplus Thibenzole ChemIDplus Tiabendazole KEGG_COMPOUND 0 C17H22N2O3 InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1 RTKIYFITIVXBLE-QEQCGCAPSA-N 302.36826 302.16304 C[C@@H](C(=O)c1ccc(cc1)N(C)C)\C=C(C)\C=C\C(=O)NO CHEBI:39145 CHEBI:46022 Beilstein:5291761 CAS:58880-19-6 DrugBank:DB04297 HMDB:HMDB0259177 KNApSAcK:C00016002 PDBeChem:TSN PMID:10490031 PMID:15346199 PMID:16010430 PMID:18285338 PMID:19038231 PMID:21504214 PMID:25075551 PMID:27454931 PMID:30395713 PMID:31755702 PMID:32880591 PMID:33983895 PMID:34086940 Wikipedia:Trichostatin_A (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide TRICHOSTATIN A chebi_ontology (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide TSA CHEBI:46024 trichostatin A CHEBI:46024 Beilstein:5291761 Beilstein CAS:58880-19-6 ChemIDplus PMID:10490031 Europe PMC PMID:15346199 Europe PMC PMID:16010430 Europe PMC PMID:18285338 Europe PMC PMID:19038231 Europe PMC PMID:21504214 Europe PMC PMID:25075551 Europe PMC PMID:27454931 Europe PMC PMID:30395713 Europe PMC PMID:31755702 Europe PMC PMID:32880591 Europe PMC PMID:33983895 Europe PMC PMID:34086940 Europe PMC (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide IUPAC TRICHOSTATIN A PDBeChem (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide ChemIDplus TSA ChemIDplus 0 C2H3N3 InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5) NSPMIYGKQJPBQR-UHFFFAOYSA-N 69.06544 69.03270 c1nnc[nH]1 CHEBI:35548 CHEBI:46076 Beilstein:605619 CAS:63598-71-0 Gmelin:323206 PDBeChem:TRI 4H-1,2,4-triazole chebi_ontology 1,2,4-TRIAZOLE CHEBI:46077 4H-1,2,4-triazole CHEBI:46077 Beilstein:605619 Beilstein CAS:63598-71-0 ChemIDplus CAS:63598-71-0 NIST Chemistry WebBook Gmelin:323206 Gmelin 4H-1,2,4-triazole IUPAC 1,2,4-TRIAZOLE PDBeChem A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. 0 C13H12F2N6O InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 RFHAOTPXVQNOHP-UHFFFAOYSA-N 306.27080 306.10407 OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F CHEBI:46079 CHEBI:5099 Beilstein:4269710 CAS:86386-73-4 DrugBank:DB00196 Drug_Central:1187 HMDB:HMDB0014342 KEGG:D00322 LINCS:LSM-2106 PDBeChem:TPF PMID:11366931 PMID:16822276 PMID:23171950 PMID:23793863 Patent:GB2099818 Patent:US4404216 Reaxys:7311650 Wikipedia:Fluconazole 2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol fluconazole chebi_ontology 2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL Biozole Diflucan Elazor Triflucan fluconazol fluconazole fluconazolum CHEBI:46081 fluconazole CHEBI:46081 Beilstein:4269710 Beilstein CAS:86386-73-4 ChemIDplus Drug_Central:1187 DrugCentral PMID:11366931 Europe PMC PMID:16822276 Europe PMC PMID:23171950 Europe PMC PMID:23793863 Europe PMC Reaxys:7311650 Reaxys 2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol IUPAC fluconazole UniProt 2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol ChemIDplus 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL PDBeChem Biozole ChEBI Diflucan ChEBI Elazor ChemIDplus Triflucan ChEBI fluconazol ChemIDplus fluconazole ChemIDplus fluconazole WHO_MedNet fluconazolum ChemIDplus A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. 0 C43H49N7O10 InChI=1S/C43H49N7O10/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53)/t25-,29-,30+,31+,32+,34+,35+/m1/s1 FEPMHVLSLDOMQC-IYPFLVAKSA-N 823.89010 823.35409 CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H]2CC(=O)CCN2C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@@H]2CCCN2C1=O)c1ccccc1 CHEBI:9998 CAS:23152-29-6 DrugBank:DB04805 KEGG:C11269 PDBeChem:VRS PMID:1493906 PMID:22934408 PMID:3097264 PMID:4142724 Reaxys:3647647 Wikipedia:Virginiamycin_S1 N-[(6R,9S,10R,13S,15aS,22S,24aS)-22-benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxypyridine-2-carboxamide Virginiamycin S1 virginiamycin S1 chebi_ontology N-((3-hydroxy-2-pyridinyl)carbonyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine rho-lactone N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine rho-lactone virginiamycin factor S CHEBI:46416 virginiamycin S1 CHEBI:46416 CAS:23152-29-6 ChemIDplus CAS:23152-29-6 KEGG COMPOUND PMID:1493906 Europe PMC PMID:22934408 Europe PMC PMID:3097264 Europe PMC PMID:4142724 Europe PMC Reaxys:3647647 Reaxys N-[(6R,9S,10R,13S,15aS,22S,24aS)-22-benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxypyridine-2-carboxamide IUPAC Virginiamycin S1 KEGG_COMPOUND virginiamycin S1 ChemIDplus N-((3-hydroxy-2-pyridinyl)carbonyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine rho-lactone ChemIDplus N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine rho-lactone ChemIDplus virginiamycin factor S ChemIDplus The (R)-enantiomer of ofloxacin. 0 C18H20FN3O4 InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m1/s1 GSDSWSVVBLHKDQ-SNVBAGLBSA-N 361.373 361.14378 C[C@@H]1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=O CAS:100986-86-5 DrugBank:DB03034 PDBeChem:XED PMID:15769740 PMID:17870541 PMID:17937485 PMID:1992111 PMID:2079448 PMID:25069865 PMID:26179954 PMID:2824776 PMID:29513966 PMID:32208173 PMID:7478164 (3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid chebi_ontology (+)-ofloxacin (R)-(+)-ofloxacin (R)-ofloxacin D-levofloxacin D-ofloxacin DR 3354 DR-3354 DR3354 R-(+)-ofloxacin R-ofloxacin dextrofloxacine CHEBI:46577 dextrofloxacin CHEBI:46577 CAS:100986-86-5 ChemIDplus PMID:15769740 Europe PMC PMID:17870541 Europe PMC PMID:17937485 Europe PMC PMID:1992111 Europe PMC PMID:2079448 Europe PMC PMID:25069865 Europe PMC PMID:26179954 Europe PMC PMID:2824776 Europe PMC PMID:29513966 Europe PMC PMID:32208173 Europe PMC PMID:7478164 Europe PMC (3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid IUPAC (+)-ofloxacin ChEBI (R)-(+)-ofloxacin ChEBI (R)-ofloxacin ChEBI D-levofloxacin DrugBank D-ofloxacin ChemIDplus DR 3354 ChEBI DR-3354 ChEBI DR3354 ChEBI R-(+)-ofloxacin ChEBI R-ofloxacin ChemIDplus dextrofloxacine PDBeChem 0 O 15.99940 15.99491 O=* CHEBI:29353 CHEBI:44607 PDBeChem:O OXO GROUP oxo chebi_ontology =O CHEBI:46629 oxo group CHEBI:46629 OXO GROUP PDBeChem oxo IUPAC =O IUPAC The class of beta-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6. 0 C7H4NO3R3 150.112 150.01912 [H][C@@]12C([*])C(=O)N1C(C(O)=O)=C([*])C2[*] PMID:18076336 PMID:19199922 PMID:19610642 PMID:19617229 PMID:19929840 PMID:21859938 Wikipedia:Carbapenem chebi_ontology CHEBI:46633 carbapenems CHEBI:46633 PMID:18076336 Europe PMC PMID:19199922 Europe PMC PMID:19610642 Europe PMC PMID:19617229 Europe PMC PMID:19929840 Europe PMC PMID:21859938 Europe PMC chebi_ontology carbapenemcarboxylic acids CHEBI:46634 carbapenemcarboxylic acid CHEBI:46634 carbapenemcarboxylic acids ChEBI In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals'). Wikipedia:Mineral mineral chebi_ontology Minerale minerales minerals mineraux CHEBI:46662 mineral CHEBI:46662 mineral ChEBI Minerale ChEBI minerales ChEBI minerals ChEBI mineraux ChEBI chebi_ontology azaalkanes CHEBI:46686 azaalkane CHEBI:46686 azaalkanes ChEBI chebi_ontology diazaalkanes CHEBI:46687 diazaalkane CHEBI:46687 diazaalkanes ChEBI chebi_ontology oxabicycloalkanes CHEBI:46733 oxabicycloalkane CHEBI:46733 oxabicycloalkanes ChEBI Any molecule that contains two amino-acid residues connected by peptide linkages. CHEBI:23835 CHEBI:4634 KEGG:C00107 Dipeptide chebi_ontology Dipeptid dipeptides CHEBI:46761 dipeptide CHEBI:46761 Dipeptide KEGG_COMPOUND Dipeptid ChEBI dipeptides ChEBI chebi_ontology pyrrolidinecarboxamides CHEBI:46770 pyrrolidinecarboxamide CHEBI:46770 pyrrolidinecarboxamides ChEBI Any ether that contains more than one ether linkage. polyether chebi_ontology polyethers CHEBI:46774 polyether CHEBI:46774 polyether ChEBI polyethers ChEBI A polyether in which the number of ether linkages is 2. diether chebi_ontology diethers CHEBI:46786 diether CHEBI:46786 diether ChEBI diethers ChEBI A liquid that can dissolve other substances (solutes) without any change in their chemical composition. Wikipedia:Solvent chebi_ontology Loesungsmittel solvant solvents CHEBI:46787 solvent CHEBI:46787 Loesungsmittel ChEBI solvant ChEBI solvents ChEBI chebi_ontology CHEBI:46812 1,3-oxazoles CHEBI:46812 chebi_ontology N-acylpiperazines CHEBI:46844 N-acylpiperazine CHEBI:46844 N-acylpiperazines ChEBI chebi_ontology N-alkylpiperazines CHEBI:46845 N-alkylpiperazine CHEBI:46845 N-alkylpiperazines ChEBI chebi_ontology N-iminopiperazines CHEBI:46847 N-iminopiperazine CHEBI:46847 N-iminopiperazines ChEBI chebi_ontology N-arylpiperazines CHEBI:46848 N-arylpiperazine CHEBI:46848 N-arylpiperazines ChEBI chebi_ontology organoammonium salts CHEBI:46850 organoammonium salt CHEBI:46850 organoammonium salts ChEBI 0 CHO2 45.01744 44.99765 *C(=O)O CHEBI:23025 CHEBI:41420 PDBeChem:FMT CARBOXY GROUP carboxy chebi_ontology -C(O)OH -CO2H -COOH carboxyl group CHEBI:46883 carboxy group CHEBI:46883 CARBOXY GROUP PDBeChem carboxy IUPAC -C(O)OH IUPAC -CO2H ChEBI -COOH IUPAC carboxyl group ChEBI A compound consisting of a peptide with attached lipid. PMID:19889045 PMID:20545290 PMID:23131643 PMID:23318669 Wikipedia:Lipopeptide chebi_ontology LP lipopeptides CHEBI:46895 lipopeptide CHEBI:46895 PMID:19889045 Europe PMC PMID:20545290 Europe PMC PMID:23131643 Europe PMC PMID:23318669 Europe PMC LP ChEBI lipopeptides ChEBI +1 C5H13N2O2 InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1 AHLPHDHHMVZTML-UHFFFAOYSA-O 133.16900 133.09715 [NH3+]CCCC([NH3+])C([O-])=O 2,5-diammoniopentanoate ornithinium ornithinium(1+) chebi_ontology ornithine monocation CHEBI:46912 ornithinium(1+) CHEBI:46912 2,5-diammoniopentanoate IUPAC ornithinium IUPAC ornithinium(1+) JCBN ornithine monocation JCBN +2 C5H14N2O2 InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+2 AHLPHDHHMVZTML-UHFFFAOYSA-P 134.17694 134.10443 [NH3+]CCCC([NH3+])C(O)=O 1-carboxybutane-1,4-diaminium ornithinediium ornithinium(2+) chebi_ontology ornithine dication CHEBI:46913 ornithinium(2+) CHEBI:46913 1-carboxybutane-1,4-diaminium IUPAC ornithinediium IUPAC ornithinium(2+) JCBN ornithine dication JCBN chebi_ontology N-methylpiperazines CHEBI:46920 N-methylpiperazine CHEBI:46920 N-methylpiperazines ChEBI Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives. chebi_ontology tetrahydropyrans CHEBI:46942 oxanes CHEBI:46942 tetrahydropyrans ChEBI chebi_ontology oxazinanes CHEBI:46952 oxazinane CHEBI:46952 oxazinanes ChEBI chebi_ontology tetrahydrofuranols CHEBI:47017 tetrahydrofuranol CHEBI:47017 tetrahydrofuranols ChEBI chebi_ontology dihydroxytetrahydrofurans CHEBI:47019 dihydroxytetrahydrofuran CHEBI:47019 dihydroxytetrahydrofurans ChEBI A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. 0 C12H17N3O4S InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 ZSKVGTPCRGIANV-ZXFLCMHBSA-N 299.34720 299.09398 [H]C(=N)NCCSC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])C1)C(O)=O CHEBI:5879 Beilstein:434624 CAS:64221-86-9 DrugBank:DB01598 Drug_Central:1426 KEGG:C06665 KEGG:D04515 LINCS:LSM-6568 PMID:1384868 PMID:17361077 PMID:24112243 PMID:24247132 PMID:2457043 PMID:24903189 PMID:25216543 PMID:25351714 PMID:9131470 Patent:BE848545 Patent:US4194047 Reaxys:434624 Wikipedia:Imipenem (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Imipenem chebi_ontology (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure Imipenem anhydrous N-formimidoyl thienamycin N-formimidoylthienamycin imipenemum CHEBI:471744 imipenem CHEBI:471744 Beilstein:434624 Beilstein CAS:64221-86-9 ChemIDplus CAS:64221-86-9 KEGG COMPOUND Drug_Central:1426 DrugCentral PMID:1384868 Europe PMC PMID:17361077 Europe PMC PMID:24112243 Europe PMC PMID:24247132 Europe PMC PMID:2457043 Europe PMC PMID:24903189 Europe PMC PMID:25216543 Europe PMC PMID:25351714 Europe PMC PMID:9131470 Europe PMC Reaxys:434624 Reaxys (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid IUPAC Imipenem KEGG_COMPOUND (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid ChemIDplus (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ChEMBL (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure ChemIDplus Imipenem anhydrous KEGG_COMPOUND N-formimidoyl thienamycin Patent N-formimidoylthienamycin ChemIDplus imipenemum ChemIDplus A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. 0 C16H15N5O7S2 InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1 OKBVVJOGVLARMR-QSWIMTSFSA-N 453.45000 453.04129 [H][C@]12SCC(C=C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)\c1csc(N)n1)C(O)=O CHEBI:3487 Beilstein:6025058 CAS:79350-37-1 DrugBank:DB00671 Drug_Central:537 KEGG:C06881 KEGG:D00258 PMID:17116681 PMID:29017833 Patent:EP30630 Patent:US4409214 7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (-)-cefixim (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefixima cefixime cefiximum CHEBI:472657 cefixime CHEBI:472657 Beilstein:6025058 Beilstein CAS:79350-37-1 ChemIDplus CAS:79350-37-1 KEGG COMPOUND Drug_Central:537 DrugCentral PMID:17116681 ChEMBL PMID:29017833 Europe PMC 7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido}-3-ethenyl-3,4-didehydrocepham-4-carboxylic acid IUPAC (-)-cefixim ChemIDplus (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC cefixima ChemIDplus cefixime ChemIDplus cefiximum ChemIDplus A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species. 0 C47H75NO17 InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 VQOXZBDYSJBXMA-NQTDYLQESA-N 926.107 925.50350 [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 CHEBI:31926 Beilstein:12153125 CAS:34786-70-4 HMDB:HMDB0242564 KEGG:C12155 LIPID_MAPS_instance:LMPK06000004 PMID:1086913 PMID:12230565 PMID:15034898 PMID:19362643 PMID:2010357 PMID:24231162 PMID:24924305 PMID:25082221 PMID:26233316 PMID:27379602 PMID:28488115 PMID:28555391 PMID:30206268 PMID:31924510 PMID:32038598 PMID:33932153 PMID:34275291 PMID:34938275 PMID:6331301 PMID:9188800 VSDB:2985 (1S,3R,4R,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid nystatin A1 chebi_ontology CHEBI:473992 nystatin A1 CHEBI:473992 Beilstein:12153125 Beilstein CAS:34786-70-4 ChemIDplus LIPID_MAPS_instance:LMPK06000004 LIPID MAPS PMID:1086913 Europe PMC PMID:12230565 Europe PMC PMID:15034898 Europe PMC PMID:19362643 Europe PMC PMID:2010357 Europe PMC PMID:24231162 Europe PMC PMID:24924305 Europe PMC PMID:25082221 Europe PMC PMID:26233316 Europe PMC PMID:27379602 Europe PMC PMID:28488115 Europe PMC PMID:28555391 Europe PMC PMID:30206268 Europe PMC PMID:31924510 Europe PMC PMID:32038598 Europe PMC PMID:33932153 Europe PMC PMID:34275291 Europe PMC PMID:34938275 Europe PMC PMID:6331301 Europe PMC PMID:9188800 Europe PMC (1S,3R,4R,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid IUPAC nystatin A1 LIPID_MAPS A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively. 0 C14H14N8O4S3 InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1 MLYYVTUWGNIJIB-BXKDBHETSA-N 454.511 454.03001 [C@]12(N(C(=C(CS1)CSC3=NN=C(S3)C)C(=O)O)C([C@H]2NC(=O)CN4C=NN=N4)=O)[H] CHEBI:3482 Beilstein:4169371 CAS:25953-19-9 DrugBank:DB01327 Drug_Central:530 HMDB:HMDB0015422 KEGG:C06880 KEGG:D02299 LINCS:LSM-34744 PMID:12569987 PMID:2083978 PMID:22011388 PMID:23702270 PMID:24462449 PMID:28543395 PMID:29017833 PMID:6176550 Patent:US3516997 Reaxys:4169371 VSDB:1910 Wikipedia:Cefazolin 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid chebi_ontology (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CEZ Cefamezin Cephamezine Cephazolidin Cephazolin Cephazoline cefazolin cefazolina cefazoline cefazolinum CHEBI:474053 cefazolin CHEBI:474053 Beilstein:4169371 Beilstein CAS:25953-19-9 ChemIDplus CAS:25953-19-9 DrugBank CAS:25953-19-9 KEGG COMPOUND CAS:25953-19-9 KEGG DRUG Drug_Central:530 DrugCentral PMID:12569987 Europe PMC PMID:2083978 Europe PMC PMID:22011388 Europe PMC PMID:23702270 Europe PMC PMID:24462449 Europe PMC PMID:28543395 Europe PMC PMID:29017833 Europe PMC PMID:6176550 Europe PMC Reaxys:4169371 Reaxys 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid IUPAC (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid IUPAC CEZ ChEBI Cefamezin ChemIDplus Cephamezine ChemIDplus Cephazolidin ChemIDplus Cephazolin ChemIDplus Cephazoline ChemIDplus cefazolin ChemIDplus cefazolina ChemIDplus cefazoline ChemIDplus cefazolinum ChemIDplus A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. 0 C52H88N10O15 InChI=1S/C52H88N10O15/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75)/t28-,29+,30+,33+,34-,35-,36+,37-,38+,40-,41-,42-,43-,44-,45-,46-/m0/s1 JYIKNQVWKBUSNH-WVDDFWQHSA-N 1093.315 1092.64306 [C@@]12(N(C[C@@H](C1)O)C([C@H]([C@@H](C)O)NC(=O)[C@](C[C@H]([C@@H](NCCN)NC([C@@H]3[C@H](CCN3C([C@H]([C@@H](CCN)O)NC(=O)[C@H]([C@@H]([C@H](C4=CC=C(C=C4)O)O)O)NC2=O)=O)O)=O)O)(NC(CCCCCCCC[C@H](C[C@H](CC)C)C)=O)[H])=O)[H] CHEBI:599509 Beilstein:8471798 CAS:162808-62-0 DrugBank:DB00520 Drug_Central:2977 KEGG:D07626 PMID:24270605 Patent:US5378804 Patent:WO9421677 (10R,12S)-N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide Caspofungin chebi_ontology (4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0 caspofungin CHEBI:474180 caspofungin CHEBI:474180 Beilstein:8471798 Beilstein CAS:162808-62-0 ChemIDplus CAS:162808-62-0 KEGG DRUG Drug_Central:2977 DrugCentral PMID:24270605 Europe PMC (10R,12S)-N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide IUPAC Caspofungin ChEMBL (4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide ChemIDplus 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0 ChEBI caspofungin ChemIDplus A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration. 0 C26H28Cl2N4O4 InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 XMAYWYJOQHXEEK-ZEQKJWHPSA-N 531.43048 530.14876 CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 Beilstein:5488107 PDBeChem:KLN (2S,4R)-ketoconazole 1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine chebi_ontology (2S,4R)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE CHEBI:47518 (2S,4R)-ketoconazole CHEBI:47518 Beilstein:5488107 Beilstein (2S,4R)-ketoconazole UniProt 1-acetyl-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine IUPAC (2S,4R)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine ChEBI 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE PDBeChem A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole. 0 C26H28Cl2N4O4 531.43048 530.14876 CHEBI:6126 Beilstein:4303081 CAS:65277-42-1 DrugBank:DB01026 Gmelin:1713206 HMDB:HMDB0012242 KEGG:D00351 Patent:DE2804096 Patent:US4144346 rac-1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine chebi_ontology (+-)-cis-1-acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine Fungarest Fungoral Ketoderm Ketoisdin Nizoral Panfungol Xolegel cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine ketoconazol ketoconazole ketoconazolum CHEBI:47519 ketoconazole CHEBI:47519 Beilstein:4303081 ChemIDplus CAS:65277-42-1 ChemIDplus CAS:65277-42-1 KEGG DRUG Gmelin:1713206 Gmelin rac-1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine IUPAC (+-)-cis-1-acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine ChemIDplus Fungarest DrugBank Fungoral DrugBank Ketoderm DrugBank Ketoisdin DrugBank Nizoral KEGG_DRUG Panfungol DrugBank Xolegel KEGG_DRUG cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine ChemIDplus ketoconazol WHO_MedNet ketoconazole ChemIDplus ketoconazole WHO_MedNet ketoconazolum ChemIDplus A peptide antibiotic that is vancomycin lacking the disaccharide moiety. 0 C53H52Cl2N8O17 InChI=1S/C53H52Cl2N8O17/c1-19(2)10-29(57-3)47(71)62-42-44(68)21-5-8-33(27(54)12-21)79-35-14-23-15-36(46(35)70)80-34-9-6-22(13-28(34)55)45(69)43-52(76)61-41(53(77)78)26-16-24(64)17-32(66)38(26)25-11-20(4-7-31(25)65)39(49(73)63-43)60-50(74)40(23)59-48(72)30(18-37(56)67)58-51(42)75/h4-9,11-17,19,29-30,39-45,57,64-66,68-70H,10,18H2,1-3H3,(H2,56,67)(H,58,75)(H,59,72)(H,60,74)(H,61,76)(H,62,71)(H,63,73)(H,77,78)/t29-,30+,39-,40-,41+,42-,43+,44-,45-/m1/s1 JHIKFOISFAQTJQ-YZANBJIASA-N 1143.92900 1142.28275 CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O)c(Cl)c2 CAS:82198-76-3 MetaCyc:CPD-15745 PMID:11470430 PMID:14649827 PMID:15785812 PMID:22177724 Reaxys:6049255 (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37,48-hexahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid chebi_ontology Aglucovancomycin B Balhimycin aglycon CHEBI:47724 vancomycin aglycone CHEBI:47724 CAS:82198-76-3 ChemIDplus PMID:11470430 Europe PMC PMID:14649827 Europe PMC PMID:15785812 Europe PMC PMID:22177724 Europe PMC Reaxys:6049255 Reaxys (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37,48-hexahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid IUPAC Aglucovancomycin B ChemIDplus Balhimycin aglycon ChemIDplus chebi_ontology aminoglycosides CHEBI:47779 aminoglycoside CHEBI:47779 aminoglycosides ChEBI chebi_ontology penamcarboxylates CHEBI:47811 penamcarboxylate CHEBI:47811 penamcarboxylates ChEBI A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. 0 C19H24N6O5S2 InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12-/t13-,17-/m1/s1 HVFLCNVBZFFHBT-ZKDACBOMSA-N 480.56100 480.12496 [H][C@]12SCC(C[N+]3(C)CCCC3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C([O-])=O CHEBI:3486 CHEBI:473919 Beilstein:7453587 CAS:88040-23-7 DrugBank:DB01413 Drug_Central:535 KEGG:C08111 KEGG:D02376 PMID:11084674 PMID:11179650 PMID:11191931 PMID:11260566 PMID:11280610 PMID:11303846 PMID:11306793 PMID:11328792 PMID:11431192 PMID:11442796 PMID:11864944 PMID:11910959 PMID:11964152 PMID:12848746 PMID:14628573 PMID:14642333 PMID:15303411 PMID:15494381 PMID:15830071 PMID:15978309 PMID:15980347 PMID:16207962 PMID:16650951 PMID:16705389 PMID:16930923 PMID:17042189 PMID:17214092 PMID:17323865 PMID:17448937 PMID:17625777 PMID:18025111 PMID:18154532 PMID:18651542 PMID:18673128 PMID:18717040 PMID:19053894 PMID:19304881 PMID:21425867 PMID:28543395 PMID:29017833 Patent:DE3307550 Patent:US4406899 Reaxys:7453587 Wikipedia:Cefepime 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylate Cefepime cefepime chebi_ontology (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CFPM cefepima cefepime cefepimum CHEBI:478164 cefepime CHEBI:478164 Beilstein:7453587 Beilstein CAS:88040-23-7 KEGG COMPOUND Drug_Central:535 DrugCentral PMID:11084674 Europe PMC PMID:11179650 Europe PMC PMID:11191931 Europe PMC PMID:11260566 Europe PMC PMID:11280610 Europe PMC PMID:11303846 Europe PMC PMID:11306793 Europe PMC PMID:11328792 Europe PMC PMID:11431192 Europe PMC PMID:11442796 Europe PMC PMID:11864944 Europe PMC PMID:11910959 Europe PMC PMID:11964152 Europe PMC PMID:12848746 Europe PMC PMID:14628573 Europe PMC PMID:14642333 Europe PMC PMID:15303411 Europe PMC PMID:15494381 Europe PMC PMID:15830071 Europe PMC PMID:15978309 Europe PMC PMID:15980347 Europe PMC PMID:16207962 Europe PMC PMID:16650951 Europe PMC PMID:16705389 Europe PMC PMID:16930923 Europe PMC PMID:17042189 Europe PMC PMID:17214092 Europe PMC PMID:17323865 Europe PMC PMID:17448937 Europe PMC PMID:17625777 Europe PMC PMID:18025111 Europe PMC PMID:18154532 Europe PMC PMID:18651542 Europe PMC PMID:18673128 Europe PMC PMID:18717040 Europe PMC PMID:19053894 Europe PMC PMID:19304881 Europe PMC PMID:21425867 Europe PMC PMID:28543395 Europe PMC PMID:29017833 Europe PMC Reaxys:7453587 Reaxys 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylate IUPAC Cefepime KEGG_COMPOUND cefepime ChEMBL (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC CFPM ChEBI cefepima ChemIDplus cefepime ChemIDplus cefepimum ChemIDplus CHEBI:27220 CHEBI:36947 chebi_ontology urea derivatives CHEBI:47857 ureas CHEBI:47857 urea derivatives ChEBI Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. chebi_ontology Indikator CHEBI:47867 indicator CHEBI:47867 Indikator ChEBI CHEBI:26762 KEGG:C15506 chebi_ontology steroid esters CHEBI:47880 steroid ester CHEBI:47880 steroid esters ChEBI 0 C3H2O3R2 86.046 86.00039 CHEBI:13600 CHEBI:1619 CHEBI:35949 KEGG:C01656 chebi_ontology 3-Keto acid 3-Oxo acid 3-oxo monocarboxylic acids 3-oxomonocarboxylic acid 3-oxomonocarboxylic acids CHEBI:47881 3-oxo monocarboxylic acid CHEBI:47881 3-Keto acid KEGG_COMPOUND 3-Oxo acid KEGG_COMPOUND 3-oxo monocarboxylic acids ChEBI 3-oxomonocarboxylic acid ChEBI 3-oxomonocarboxylic acids ChEBI Any steroid substituted by at least one carboxy group. chebi_ontology steroid acids CHEBI:47891 steroid acid CHEBI:47891 steroid acids ChEBI Any primary amide having its amide oxygen replaced by sulfur. chebi_ontology thioamide thiocarboxamides thionoamide CHEBI:47956 thiocarboxamide CHEBI:47956 thioamide ChEBI thiocarboxamides ChEBI thionoamide ChEBI Ethers ROR' where R has a double bond adjacent to the oxygen of the ether linkage. 0 C2OR4 40.02080 39.99491 [*]\C([*])=C(\[*])O[*] enol ether chebi_ontology enol ethers CHEBI:47985 enol ether CHEBI:47985 enol ether ChEBI enol ethers ChEBI A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. chebi_ontology protein synthesis antagonist protein synthesis antagonists protein synthesis inhibitors CHEBI:48001 protein synthesis inhibitor CHEBI:48001 protein synthesis antagonist ChEBI protein synthesis antagonists ChEBI protein synthesis inhibitors ChEBI A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. 0 C16H24O4 InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1 KQNZDYYTLMIZCT-KQPMLPITSA-N 280.35936 280.16746 [H][C@@]12C[C@H](O)C[C@@]1([H])[C@H](O)\C=C\C(=O)O[C@@H](C)CCC\C=C\2 Beilstein:25191 Beilstein:5282047 CAS:20350-15-6 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one Brefeldin A chebi_ontology ascotoxin cyanein decumbin CHEBI:48080 brefeldin A CHEBI:48080 Beilstein:25191 Beilstein Beilstein:5282047 Beilstein CAS:20350-15-6 ChemIDplus (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one IUPAC Brefeldin A ChemIDplus ascotoxin ChemIDplus cyanein ChemIDplus decumbin ChemIDplus A racemate composed of equimolar amounts of (2S,3R)- and (2R,3S)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms. 0 C17H13ClFN3O 329.75600 329.07312 CAS:133855-98-8 KEGG:C11229 PMID:24274332 PMID:24364671 PMID:24550150 Pesticides:epoxiconazole Reaxys:8150613 Wikipedia:Epoxiconazole rac-1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole chebi_ontology (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole CHEBI:4811 epoxiconazole CHEBI:4811 CAS:133855-98-8 ChemIDplus CAS:133855-98-8 KEGG COMPOUND PMID:24274332 Europe PMC PMID:24364671 Europe PMC PMID:24550150 Europe PMC Pesticides:epoxiconazole Alan Wood's Pesticides Reaxys:8150613 Reaxys rac-1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole IUPAC (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole Alan_Wood's_Pesticides rel-1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole Alan_Wood's_Pesticides An olefin that contains more than one carbon-carbon double bond. chebi_ontology polyenes CHEBI:48121 polyene CHEBI:48121 polyenes ChEBI A polyketide based on a tetracene ring structure. chebi_ontology tetracenomycins CHEBI:48132 tetracenomycin CHEBI:48132 tetracenomycins ChEBI chebi_ontology Schwefeloxide oxides of sulfur sulfur oxides CHEBI:48154 sulfur oxide CHEBI:48154 Schwefeloxide ChEBI oxides of sulfur ChEBI sulfur oxides ChEBI An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. chebi_ontology Desinfektionsmittel desinfectant disinfectants disinfecting agent CHEBI:48219 disinfectant CHEBI:48219 Desinfektionsmittel ChEBI desinfectant ChEBI disinfectants ChEBI disinfecting agent ChEBI A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. 0 C26H28Cl2N4O4 InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1 XMAYWYJOQHXEEK-OZXSUGGESA-N 531.43100 530.14876 CC(=O)N1CCN(CC1)c1ccc(OC[C@H]2CO[C@@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 Beilstein:4241048 LINCS:LSM-5430 PDBeChem:KKK Reaxys:4241048 (2R,4S)-ketoconazole 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine chebi_ontology (2R,4S)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine CHEBI:48336 (2R,4S)-ketoconazole CHEBI:48336 Beilstein:4241048 Beilstein Reaxys:4241048 Reaxys (2R,4S)-ketoconazole UniProt 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine IUPAC (2R,4S)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine ChEBI A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively. 0 C26H28Cl2N4O4 InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3 XMAYWYJOQHXEEK-UHFFFAOYSA-N 531.43048 530.14876 CC(=O)N1CCN(CC1)c1ccc(OCC2COC(Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 Beilstein:634785 DrugBank:DB01026 LINCS:LSM-5148 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine chebi_ontology CHEBI:48339 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine CHEBI:48339 Beilstein:634785 Beilstein 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine IUPAC Compounds of structure RSSR'. chebi_ontology disulfides CHEBI:48343 disulfide CHEBI:48343 disulfides ChEBI A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. polar solvent chebi_ontology polar solvents CHEBI:48354 polar solvent CHEBI:48354 polar solvent IUPAC polar solvents ChEBI chebi_ontology CHEBI:48355 non-polar solvent CHEBI:48355 A polar solvent that is capable of acting as a hydron (proton) donor. protogenic solvent chebi_ontology CHEBI:48356 protic solvent CHEBI:48356 protogenic solvent IUPAC Solvent that is capable of acting as a hydron (proton) acceptor. protophilic solvent chebi_ontology HBA solvent hydrogen bond acceptor solvent CHEBI:48359 protophilic solvent CHEBI:48359 protophilic solvent IUPAC HBA solvent ChEBI hydrogen bond acceptor solvent ChEBI Self-ionizing solvent possessing both characteristics of Bronsted acids and bases. amphiprotic solvent chebi_ontology CHEBI:48360 amphiprotic solvent CHEBI:48360 amphiprotic solvent IUPAC 0 CH4N2O InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4) XSQUKJJJFZCRTK-UHFFFAOYSA-N 60.05534 60.03236 NC(O)=N Beilstein:773698 CAS:4744-36-9 carbamimidic acid chebi_ontology H2N-C(=NH)-OH H2N-C(OH)=NH HO-C(=NH)-NH2 Isoharnstoff carbamimic acid carbonamidimidic acid isourea pseudourea CHEBI:48376 carbamimidic acid CHEBI:48376 Beilstein:773698 Beilstein CAS:4744-36-9 ChemIDplus carbamimidic acid IUPAC H2N-C(=NH)-OH IUPAC H2N-C(OH)=NH IUPAC HO-C(=NH)-NH2 IUPAC Isoharnstoff ChEBI carbamimic acid ChemIDplus carbonamidimidic acid IUPAC isourea ChemIDplus pseudourea ChemIDplus Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH). imidic acid imidic acids chebi_ontology imidic acids imino acids CHEBI:48377 imidic acid CHEBI:48377 imidic acid ChEBI imidic acids IUPAC imidic acids ChEBI imino acids IUPAC carboximidic acid carboximidic acids chebi_ontology carboximidic acids CHEBI:48378 carboximidic acid CHEBI:48378 carboximidic acid ChEBI carboximidic acids IUPAC carboximidic acids ChEBI A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives. isoureas chebi_ontology isoureas CHEBI:48379 isourea CHEBI:48379 isoureas IUPAC isoureas ChEBI An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. CHEBI:67170 Wikipedia:Angiogenesis_inhibitor chebi_ontology angiogenesis antagonist angiostatic agents anti-angiogenic agent CHEBI:48422 angiogenesis inhibitor CHEBI:48422 angiogenesis antagonist ChEBI angiostatic agents ChEBI anti-angiogenic agent ChEBI chebi_ontology aryloxypyrimidines CHEBI:48535 aryloxypyrimidine CHEBI:48535 aryloxypyrimidines ChEBI chebi_ontology piperidone CHEBI:48589 piperidones CHEBI:48589 piperidone ChEBI chebi_ontology pyranoindolizinoquinolines CHEBI:48626 pyranoindolizinoquinoline CHEBI:48626 pyranoindolizinoquinolines ChEBI Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. agonist chebi_ontology agonista agoniste agonists CHEBI:48705 agonist CHEBI:48705 agonist IUPAC agonista ChEBI agoniste ChEBI agonists ChEBI Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. antagonist chebi_ontology antagonista antagoniste antagonists CHEBI:48706 antagonist CHEBI:48706 antagonist IUPAC antagonista ChEBI antagoniste ChEBI antagonists ChEBI An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. 0 C10H24N2O2 InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3/t9-,10-/m0/s1 AEUTYOVWOVBAKS-UWVGGRQHSA-N 204.30980 204.18378 CC[C@@H](CO)NCCN[C@@H](CC)CO CHEBI:133410 CHEBI:659237 CHEBI:678172 Beilstein:6312870 CAS:74-55-5 DrugBank:DB00330 Drug_Central:1073 KEGG:C06984 KEGG:D07925 PMID:10649975 PMID:10891117 PMID:10966749 PMID:12182855 PMID:14695841 PMID:14698152 PMID:15225698 PMID:16005211 PMID:16759086 PMID:16870429 PMID:17210775 PMID:17239593 PMID:17276683 PMID:17315960 PMID:17331717 PMID:17562368 PMID:17851083 PMID:17888665 PMID:19524332 PMID:19648006 PMID:3934384 Reaxys:6312870 Wikipedia:Ethambutol (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol Ethambutol chebi_ontology (+)-2,2'-(ethylenediimino)di-1-butanol (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine (+)-S,S-ethambutol (+)-ethambutol (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol (S,S)-ethambutol EMB S,S-Ethambutol etambutol ethambutol ethambutolum CHEBI:4877 ethambutol CHEBI:4877 Beilstein:6312870 Beilstein CAS:74-55-5 ChemIDplus CAS:74-55-5 KEGG COMPOUND Drug_Central:1073 DrugCentral PMID:10649975 ChEMBL PMID:10891117 ChEMBL PMID:10966749 ChEMBL PMID:12182855 ChEMBL PMID:14695841 ChEMBL PMID:14698152 ChEMBL PMID:15225698 ChEMBL PMID:16005211 ChEMBL PMID:16759086 ChEMBL PMID:16870429 ChEMBL PMID:17210775 ChEMBL PMID:17239593 ChEMBL PMID:17276683 ChEMBL PMID:17315960 ChEMBL PMID:17331717 ChEMBL PMID:17562368 ChEMBL PMID:17851083 ChEMBL PMID:17888665 ChEMBL PMID:19524332 ChEMBL PMID:19648006 ChEMBL PMID:3934384 ChEMBL Reaxys:6312870 Reaxys (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol IUPAC Ethambutol KEGG_COMPOUND (+)-2,2'-(ethylenediimino)di-1-butanol ChemIDplus (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine ChemIDplus (+)-S,S-ethambutol ChemIDplus (+)-ethambutol ChEBI (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol ChEBI (S,S)-ethambutol ChEBI EMB ChEBI S,S-Ethambutol ChEMBL etambutol ChemIDplus ethambutol ChemIDplus ethambutolum ChemIDplus 0 CN 26.017 26.00307 C(#N)* CHEBI:36824 CHEBI:48818 PDBeChem:CYN cyanido cyano chebi_ontology -C#N -CN CYANIDE GROUP NC- carbonitrile group CHEBI:48819 cyano group CHEBI:48819 cyanido IUPAC cyano IUPAC -C#N IUPAC -CN IUPAC CYANIDE GROUP PDBeChem NC- IUPAC carbonitrile group ChEBI 0 C21H38O8 InChI=1S/C21H38O8/c1-8-14-21(7,28)18(25)11(3)15(22)10(2)9-20(6,27)17(24)12(4)16(23)13(5)19(26)29-14/h10-14,16-18,23-25,27-28H,8-9H2,1-7H3/t10-,11+,12+,13-,14-,16+,17-,18-,20-,21-/m1/s1 YVTFLQUPRIIRFE-QUMKBVJLSA-N 418.52162 418.25667 CC[C@H]1OC(=O)[C@H](C)[C@@H](O)[C@H](C)[C@@H](O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O Beilstein:4570921 CAS:26754-37-0 (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-4,6,7,12,13-pentahydroxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione chebi_ontology Erythronolid A CHEBI:48848 erythronolide A CHEBI:48848 Beilstein:4570921 Beilstein CAS:26754-37-0 ChemIDplus (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-4,6,7,12,13-pentahydroxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione IUPAC Erythronolid A ChEBI A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide. 0 C8H10N2S InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11) AEOCXXJPGCBFJA-UHFFFAOYSA-N 166.24448 166.05647 CCc1cc(ccn1)C(N)=S Beilstein:116474 CAS:536-33-4 DrugBank:DB00609 Drug_Central:1083 HMDB:HMDB0014747 KEGG:C07665 KEGG:D00591 LINCS:LSM-5620 PMID:14651620 PMID:15673755 PMID:15850780 Patent:GB800250 Reaxys:116474 Wikipedia:Ethionamide 2-ethylpyridine-4-carbothioamide Ethionamide ethionamide chebi_ontology 2-ethyl-4-thiopyridylamide ETH ETP Ethinamide Ethioniamide Ethylisothiamide Ethyonomide Etionamid Etionamide Etioniamid Trecator ethionamidum etionamida CHEBI:4885 ethionamide CHEBI:4885 Beilstein:116474 Beilstein CAS:536-33-4 ChemIDplus CAS:536-33-4 KEGG COMPOUND CAS:536-33-4 NIST Chemistry WebBook Drug_Central:1083 DrugCentral PMID:14651620 Europe PMC PMID:15673755 Europe PMC PMID:15850780 Europe PMC Reaxys:116474 Reaxys 2-ethylpyridine-4-carbothioamide IUPAC Ethionamide KEGG_COMPOUND ethionamide UniProt 2-ethyl-4-thiopyridylamide ChEBI ETH DrugBank ETP DrugBank Ethinamide DrugBank Ethioniamide DrugBank Ethylisothiamide DrugBank Ethyonomide DrugBank Etionamid DrugBank Etionamide DrugBank Etioniamid DrugBank Trecator ChemIDplus ethionamidum ChemIDplus etionamida ChemIDplus 0 H2O3S InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3) LSNNMFCWUKXFEE-UHFFFAOYSA-N 82.08008 81.97247 OS(O)=O CHEBI:26837 CHEBI:9344 CAS:7782-99-2 Gmelin:1458 KEGG:C00094 KNApSAcK:C00019662 PDBeChem:SO3 UM-BBD_compID:c0348 Sulfurous acid dihydrogen trioxosulfate dihydroxidooxidosulfur sulfurous acid trioxosulfuric acid chebi_ontology H2SO3 S(O)(OH)2 Sulfite [SO(OH)2] acide sulfureux acido sulfuroso schweflige Saeure sulphurous acid CHEBI:48854 sulfurous acid CHEBI:48854 CAS:7782-99-2 ChemIDplus Gmelin:1458 Gmelin UM-BBD_compID:c0348 UM-BBD Sulfurous acid KEGG_COMPOUND dihydrogen trioxosulfate IUPAC dihydroxidooxidosulfur IUPAC sulfurous acid IUPAC trioxosulfuric acid IUPAC H2SO3 IUPAC S(O)(OH)2 IUPAC Sulfite KEGG_COMPOUND [SO(OH)2] IUPAC acide sulfureux ChEBI acido sulfuroso ChEBI schweflige Saeure ChemIDplus sulphurous acid ChemIDplus chebi_ontology thiazolidinones CHEBI:48891 thiazolidinone CHEBI:48891 thiazolidinones ChEBI An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom. chebi_ontology thiazole CHEBI:48901 thiazoles CHEBI:48901 thiazole ChEBI chebi_ontology triazolobenzothiazoles CHEBI:48908 triazolobenzothiazole CHEBI:48908 triazolobenzothiazoles ChEBI Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus). DrugBank:DB00199 HMDB:HMDB0014344 Patent:US2653899 Wikipedia:Erythromycin chebi_ontology eritromicina erthromycin erythromycine CHEBI:48923 erythromycin CHEBI:48923 eritromicina ChEBI erthromycin ChEBI erythromycine ChEBI Any azo compound containing two -N=N- groups. bis(azo) compound chebi_ontology bis(azo) compounds CHEBI:48960 bis(azo) compound CHEBI:48960 bis(azo) compound IUPAC bis(azo) compounds ChEBI chebi_ontology substituted anilines CHEBI:48975 substituted aniline CHEBI:48975 substituted anilines ChEBI A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. chebi_ontology hormone antagonists CHEBI:49020 hormone antagonist CHEBI:49020 hormone antagonists ChEBI chebi_ontology drug metabolites CHEBI:49103 drug metabolite CHEBI:49103 drug metabolites ChEBI A drug used to treat asthma. chebi_ontology anti-asthmatic agent anti-asthmatic agents anti-asthmatic drugs CHEBI:49167 anti-asthmatic drug CHEBI:49167 anti-asthmatic agent ChEBI anti-asthmatic agents ChEBI anti-asthmatic drugs ChEBI chebi_ontology CHEBI:49318 piperidine antibiotic CHEBI:49318 chebi_ontology CHEBI:49319 carbocyclic antibiotic CHEBI:49319 0 H InChI=1S/H YZCKVEUIGOORGS-UHFFFAOYSA-N 1.00794 1.00783 [H] CHEBI:24634 CHEBI:49636 WebElements:H hydrogen chebi_ontology 1H H Wasserstoff hidrogeno hydrogen hydrogene CHEBI:49637 hydrogen atom CHEBI:49637 hydrogen IUPAC 1H IUPAC H IUPAC Wasserstoff ChEBI hidrogeno ChEBI hydrogen ChEBI hydrogene ChEBI A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union. 0 C17H12Cl2N2O 331.19600 330.03267 CAS:60168-88-9 HMDB:HMDB0040599 KEGG:C11226 PMID:12146625 PMID:14700530 PMID:15866470 PMID:18372651 PMID:22955670 PMID:23664474 PMID:8637508 Patent:US3818009 Patent:US3869456 Patent:US3887708 Pesticides:fenarimol Reaxys:5972869 Wikipedia:Fenarimol fenarimol rac-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol chebi_ontology (+-)-2,4'-dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol (+-)-fenarimol (2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol (RS)-2,4'-dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol 2,4'-dichloro-alpha(pyrimidin-5-yl)benzhydryl alcohol EL 222 Rimidin Rubigan alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol rac-(R)-(2-chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol rac-fenarimol CHEBI:4998 fenarimol CHEBI:4998 CAS:60168-88-9 Alan Wood's Pesticides CAS:60168-88-9 ChemIDplus CAS:60168-88-9 KEGG COMPOUND CAS:60168-88-9 NIST Chemistry WebBook PMID:12146625 Europe PMC PMID:14700530 Europe PMC PMID:15866470 Europe PMC PMID:18372651 Europe PMC PMID:22955670 Europe PMC PMID:23664474 Europe PMC PMID:8637508 Europe PMC Pesticides:fenarimol Alan Wood's Pesticides Reaxys:5972869 Reaxys fenarimol ChEBI rac-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol IUPAC (+-)-2,4'-dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol ChemIDplus (+-)-fenarimol HMDB (2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol NIST_Chemistry_WebBook (RS)-2,4'-dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol Alan_Wood's_Pesticides 2,4'-dichloro-alpha(pyrimidin-5-yl)benzhydryl alcohol NIST_Chemistry_WebBook EL 222 NIST_Chemistry_WebBook Rimidin NIST_Chemistry_WebBook Rubigan NIST_Chemistry_WebBook alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol Alan_Wood's_Pesticides rac-(R)-(2-chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol Alan_Wood's_Pesticides rac-fenarimol ChEBI An organosulfonic acid comprising stilbene having 4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino groups at the 4 and 4'-positions and sulfo groups at the 2- and 2'-positions. 0 C40H44N12O10S2 InChI=1S/C40H44N12O10S2/c53-21-17-51(18-22-54)39-47-35(41-29-7-3-1-4-8-29)45-37(49-39)43-31-15-13-27(33(25-31)63(57,58)59)11-12-28-14-16-32(26-34(28)64(60,61)62)44-38-46-36(42-30-9-5-2-6-10-30)48-40(50-38)52(19-23-55)20-24-56/h1-16,25-26,53-56H,17-24H2,(H,57,58,59)(H,60,61,62)(H2,41,43,45,47,49)(H2,42,44,46,48,50) CNGYZEMWVAWWOB-UHFFFAOYSA-N 916.98424 916.27448 [H]C(=C([H])c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S(O)(=O)=O)c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S(O)(=O)=O Beilstein:604239 CAS:4404-43-7 PMID:11015407 PMID:15038150 PMID:17252623 PMID:2580370 PMID:3061981 PMID:7181601 Reaxys:8385272 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonic acid] chebi_ontology 4,4'-bis((4-(bis(2-hydroxyethyl)amino)-6-anilino-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonic acid 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonic acid 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid C.I. Fluorescent brightening agent 28 Calcofluor M2R Calcofluor White M2R CHEBI:50010 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid CHEBI:50010 Beilstein:604239 Beilstein CAS:4404-43-7 ChemIDplus PMID:11015407 Europe PMC PMID:15038150 Europe PMC PMID:17252623 Europe PMC PMID:2580370 Europe PMC PMID:3061981 Europe PMC PMID:7181601 Europe PMC Reaxys:8385272 Reaxys 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonic acid] IUPAC 4,4'-bis((4-(bis(2-hydroxyethyl)amino)-6-anilino-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonic acid ChemIDplus 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonic acid ChemIDplus 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid ChemIDplus C.I. Fluorescent brightening agent 28 ChemIDplus Calcofluor M2R ChemIDplus Calcofluor White M2R ChemIDplus 0 C40H42N12Na2O10S2 InChI=1S/C40H44N12O10S2.2Na/c53-21-17-51(18-22-54)39-47-35(41-29-7-3-1-4-8-29)45-37(49-39)43-31-15-13-27(33(25-31)63(57,58)59)11-12-28-14-16-32(26-34(28)64(60,61)62)44-38-46-36(42-30-9-5-2-6-10-30)48-40(50-38)52(19-23-55)20-24-56;;/h1-16,25-26,53-56H,17-24H2,(H,57,58,59)(H,60,61,62)(H2,41,43,45,47,49)(H2,42,44,46,48,50);;/q;2*+1/p-2 YJHDFAAFYNRKQE-UHFFFAOYSA-L 960.94790 960.23837 [Na+].[Na+].[H]C(=C([H])c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S([O-])(=O)=O)c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S([O-])(=O)=O Beilstein:8385272 CAS:4193-55-9 disodium 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonate] chebi_ontology 4,4'-bis((2-anilino-4-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-6-yl)amino)stilbene-2,2'-disulfonic acid, disodium salt 4,4'-bis((4-anilino-6-bis(2-hydroxyethyl)amino-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid, disodium salt C.I. 40622 C.I. Fluorescent Brightening Agent 28, disodium salt Calcofluor White LRP Calcofluor White M 2R Calcofluor White ST Cellufluor Fluorescent Brightener 28 disodium 4,4'-bis(6-anilino-(4-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonate CHEBI:50011 Calcofluor White CHEBI:50011 Beilstein:8385272 Beilstein CAS:4193-55-9 ChemIDplus disodium 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonate] IUPAC 4,4'-bis((2-anilino-4-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-6-yl)amino)stilbene-2,2'-disulfonic acid, disodium salt ChemIDplus 4,4'-bis((4-anilino-6-bis(2-hydroxyethyl)amino-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid, disodium salt ChemIDplus C.I. 40622 ChEBI C.I. Fluorescent Brightening Agent 28, disodium salt ChemIDplus Calcofluor White LRP ChemIDplus Calcofluor White M 2R ChemIDplus Calcofluor White ST ChemIDplus Cellufluor ChemIDplus Fluorescent Brightener 28 ChemIDplus disodium 4,4'-bis(6-anilino-(4-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonate ChemIDplus An arenesulfonate arising from deprotonation of the sulfo groups of 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid. -2 C40H42N12O10S2 InChI=1S/C40H44N12O10S2/c53-21-17-51(18-22-54)39-47-35(41-29-7-3-1-4-8-29)45-37(49-39)43-31-15-13-27(33(25-31)63(57,58)59)11-12-28-14-16-32(26-34(28)64(60,61)62)44-38-46-36(42-30-9-5-2-6-10-30)48-40(50-38)52(19-23-55)20-24-56/h1-16,25-26,53-56H,17-24H2,(H,57,58,59)(H,60,61,62)(H2,41,43,45,47,49)(H2,42,44,46,48,50)/p-2 CNGYZEMWVAWWOB-UHFFFAOYSA-L 914.96836 914.25993 [H]C(=C([H])c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S([O-])(=O)=O)c1ccc(Nc2nc(Nc3ccccc3)nc(n2)N(CCO)CCO)cc1S([O-])(=O)=O 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonate] chebi_ontology CHEBI:50012 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonate CHEBI:50012 2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonate] IUPAC A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. chebi_ontology organic amino compounds CHEBI:50047 organic amino compound CHEBI:50047 organic amino compounds ChEBI An agent that binds to and activates excitatory amino acid receptors. chebi_ontology excitatory amino acid agonists excitatory amino acid receptor agonist excitatory amino acid receptor agonists CHEBI:50103 excitatory amino acid agonist CHEBI:50103 excitatory amino acid agonists ChEBI excitatory amino acid receptor agonist ChEBI excitatory amino acid receptor agonists ChEBI Any anion formed by loss of a proton from a steroid acid. chebi_ontology steroid acid anions CHEBI:50160 steroid acid anion CHEBI:50160 steroid acid anions ChEBI A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. chebi_ontology desquamating agent keratolytic agent keratolytic drugs skin-peeling agent CHEBI:50176 keratolytic drug CHEBI:50176 desquamating agent ChEBI keratolytic agent ChEBI keratolytic drugs ChEBI skin-peeling agent ChEBI A drug used to treat or prevent skin disorders or for the routine care of skin. chebi_ontology dermatologic agent dermatologic drugs dermatological agent CHEBI:50177 dermatologic drug CHEBI:50177 dermatologic agent ChEBI dermatologic drugs ChEBI dermatological agent ChEBI An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. chebi_ontology CYP2D6 inhibitor CYP2D6 inhibitors P450 inhibitors cytochrome P450 inhibitor cytochrome P450 inhibitors CHEBI:50183 P450 inhibitor CHEBI:50183 CYP2D6 inhibitor ChEBI CYP2D6 inhibitors ChEBI P450 inhibitors ChEBI cytochrome P450 inhibitor ChEBI cytochrome P450 inhibitors ChEBI Any pathway inhibitor that inhibits the synthesis of fatty acids. chebi_ontology fatty acid synthesis inhibitors CHEBI:50185 fatty acid synthesis inhibitor CHEBI:50185 fatty acid synthesis inhibitors ChEBI Any protective agent counteracting or neutralizing the action of poisons. chebi_ontology antidotes CHEBI:50247 antidote CHEBI:50247 antidotes ChEBI Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. chebi_ontology hematologic agents CHEBI:50248 hematologic agent CHEBI:50248 hematologic agents ChEBI An agent that prevents blood clotting. chebi_ontology anticoagulante anticoagulants CHEBI:50249 anticoagulant CHEBI:50249 anticoagulante ChEBI anticoagulants ChEBI A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. PMID:23993918 PMID:23998799 PMID:24329110 PMID:24628402 PMID:24709544 PMID:25144792 PMID:25157234 PMID:25269430 PMID:25391982 PMID:25591121 PMID:25620096 PMID:25795057 PMID:26028253 PMID:26184144 PMID:28070577 PMID:28215138 PMID:28219047 PMID:28259775 PMID:28319647 PMID:28329729 PMID:28334528 Wikipedia:Prodrug chebi_ontology Prodrugs CHEBI:50266 prodrug CHEBI:50266 PMID:23993918 Europe PMC PMID:23998799 Europe PMC PMID:24329110 Europe PMC PMID:24628402 Europe PMC PMID:24709544 Europe PMC PMID:25144792 Europe PMC PMID:25157234 Europe PMC PMID:25269430 Europe PMC PMID:25391982 Europe PMC PMID:25591121 Europe PMC PMID:25620096 Europe PMC PMID:25795057 Europe PMC PMID:26028253 Europe PMC PMID:26184144 Europe PMC PMID:28070577 Europe PMC PMID:28215138 Europe PMC PMID:28219047 Europe PMC PMID:28259775 Europe PMC PMID:28319647 Europe PMC PMID:28329729 Europe PMC PMID:28334528 Europe PMC Prodrugs ChEBI Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. chebi_ontology chemoprotectant chemoprotectants chemoprotective agent chemoprotective agents protective agents CHEBI:50267 protective agent CHEBI:50267 chemoprotectant ChEBI chemoprotectants ChEBI chemoprotective agent ChEBI chemoprotective agents ChEBI protective agents ChEBI A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. chebi_ontology DNA topoisomerase inhibitor DNA topoisomerase inhibitors EC 5.99.1.2 (DNA topoisomerase) inhibitors EC 5.99.1.2 (topoisomerase I) inhibitor EC 5.99.1.2 (topoisomerase I) inhibitors EC 5.99.1.2 inhibitor EC 5.99.1.2 inhibitors topoisomerase I (EC 5.99.1.2) inhibitor topoisomerase I (EC 5.99.1.2) inhibitors topoisomerase I inhibitor topoisomerase I inhibitors type I DNA topoisomerase inhibitor type I DNA topoisomerase inhibitors CHEBI:50276 EC 5.99.1.2 (DNA topoisomerase) inhibitor CHEBI:50276 DNA topoisomerase inhibitor ChEBI DNA topoisomerase inhibitors ChEBI EC 5.99.1.2 (DNA topoisomerase) inhibitors ChEBI EC 5.99.1.2 (topoisomerase I) inhibitor ChEBI EC 5.99.1.2 (topoisomerase I) inhibitors ChEBI EC 5.99.1.2 inhibitor ChEBI EC 5.99.1.2 inhibitors ChEBI topoisomerase I (EC 5.99.1.2) inhibitor ChEBI topoisomerase I (EC 5.99.1.2) inhibitors ChEBI topoisomerase I inhibitor ChEBI topoisomerase I inhibitors ChEBI type I DNA topoisomerase inhibitor ChEBI type I DNA topoisomerase inhibitors ChEBI chebi_ontology canonical nucleotide residues CHEBI:50297 canonical nucleotide residue CHEBI:50297 canonical nucleotide residues ChEBI chebi_ontology canonical ribonucleotide residues CHEBI:50299 canonical ribonucleotide residue CHEBI:50299 canonical ribonucleotide residues ChEBI chebi_ontology CHEBI:50312 onium compound CHEBI:50312 Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families. onium cations chebi_ontology onium cations onium ion onium ions CHEBI:50313 onium cation CHEBI:50313 onium cations IUPAC onium cations ChEBI onium ion ChEBI onium ions ChEBI +1 ClH2 InChI=1S/ClH2/h1H2/q+1 IGJWHVUMEJASKV-UHFFFAOYSA-N 37.46858 36.98395 [H][Cl+][H] Gmelin:331 chloranium chloronium chebi_ontology H2Cl(+) [ClH2](+) CHEBI:50315 chloronium CHEBI:50315 Gmelin:331 Gmelin chloranium IUPAC chloronium IUPAC H2Cl(+) IUPAC [ClH2](+) IUPAC chebi_ontology nucleotide residues CHEBI:50319 nucleotide residue CHEBI:50319 nucleotide residues ChEBI chebi_ontology nucleoside residues CHEBI:50320 nucleoside residue CHEBI:50320 nucleoside residues ChEBI A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid. chebi_ontology canonical amino-acid side-chain canonical amino-acid side-chains proteinogenic amino-acid side-chain proteinogenic amino-acid side-chain groups proteinogenic amino-acid side-chains CHEBI:50325 proteinogenic amino-acid side-chain group CHEBI:50325 canonical amino-acid side-chain ChEBI canonical amino-acid side-chains ChEBI proteinogenic amino-acid side-chain ChEBI proteinogenic amino-acid side-chain groups ChEBI proteinogenic amino-acid side-chains ChEBI chebi_ontology organic nitrogen anions CHEBI:50335 organic nitrogen anion CHEBI:50335 organic nitrogen anions ChEBI Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties. PMID:22039784 PMID:22039799 PMID:22542398 PMID:23165468 PMID:8688633 Wikipedia:Avermectin avermectin chebi_ontology avermectins CHEBI:50344 avermectin CHEBI:50344 PMID:22039784 Europe PMC PMID:22039799 Europe PMC PMID:22542398 Europe PMC PMID:23165468 Europe PMC PMID:8688633 Europe PMC avermectin ChEBI avermectins ChEBI chebi_ontology emamectin CHEBI:50346 emamectins CHEBI:50346 emamectin ChEBI A role played by a molecular entity used to study the microscopic environment. chebi_ontology CHEBI:50406 probe CHEBI:50406 A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH2 where R is an aryl group. 0 H2NR 16.023 16.01872 [H]N(*)[H] primary arylamine chebi_ontology an arylamine CHEBI:50471 primary arylamine CHEBI:50471 primary arylamine ChEBI an arylamine UniProt Any compound containing the thiocarbonyl group, C=S. chebi_ontology thiocarbonyl compounds CHEBI:50492 thiocarbonyl compound CHEBI:50492 thiocarbonyl compounds ChEBI An organic anion arising from deprotonation of the OH function of a phenol compound. chebi_ontology phenolate anions CHEBI:50525 phenolate anion CHEBI:50525 phenolate anions ChEBI chebi_ontology CHEBI:50533 protein denaturant CHEBI:50533 An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position. CHEBI:22937 CHEBI:50581 chebi_ontology alkyl alcohols hydroxyalkane hydroxyalkanes CHEBI:50584 alkyl alcohol CHEBI:50584 alkyl alcohols ChEBI hydroxyalkane ChEBI hydroxyalkanes ChEBI EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis. chebi_ontology EC 3.5.1.5 (urease) inhibitors EC 3.5.1.5 inhibitor EC 3.5.1.5 inhibitors urea amidohydrolase inhibitor urea amidohydrolase inhibitors urease (EC 3.5.1.5) inhibitor urease (EC 3.5.1.5) inhibitors urease inhibitor urease inhibitors CHEBI:50635 EC 3.5.1.5 (urease) inhibitor CHEBI:50635 EC 3.5.1.5 (urease) inhibitors ChEBI EC 3.5.1.5 inhibitor ChEBI EC 3.5.1.5 inhibitors ChEBI urea amidohydrolase inhibitor ChEBI urea amidohydrolase inhibitors ChEBI urease (EC 3.5.1.5) inhibitor ChEBI urease (EC 3.5.1.5) inhibitors ChEBI urease inhibitor ChEBI urease inhibitors ChEBI -1 C16H18N3O4S InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/p-1/t9-,10-,11+,14-/m1/s1 AVKUERGKIZMTKX-NJBDSQKTSA-M 348.39794 348.10235 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C([O-])=O 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate ampicillinate CHEBI:50658 ampicillin(1-) CHEBI:50658 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC ampicillinate ChEBI An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3). Wikipedia:Dihydrofolate_reductase_inhibitor chebi_ontology 7,8-dihydrofolate reductase inhibitor 7,8-dihydrofolate reductase inhibitors DHFR inhibitor DHFR inhibitors EC 1.5.1.3 (dihydrofolate reductase) inhibitors EC 1.5.1.3 inhibitor EC 1.5.1.3 inhibitors NADPH-dihydrofolate reductase inhibitor NADPH-dihydrofolate reductase inhibitors dihydrofolate reductase (EC 1.5.1.3) inhibitor dihydrofolate reductase (EC 1.5.1.3) inhibitors dihydrofolate reductase inhibitor dihydrofolate reductase inhibitors dihydrofolic acid reductase inhibitor dihydrofolic acid reductase inhibitors dihydrofolic reductase inhibitor dihydrofolic reductase inhibitors folic acid reductase inhibitor folic acid reductase inhibitors folic reductase inhibitor folic reductase inhibitors tetrahydrofolate dehydrogenase inhibitor tetrahydrofolate dehydrogenase inhibitors CHEBI:50683 EC 1.5.1.3 (dihydrofolate reductase) inhibitor CHEBI:50683 7,8-dihydrofolate reductase inhibitor ChEBI 7,8-dihydrofolate reductase inhibitors ChEBI DHFR inhibitor ChEBI DHFR inhibitors ChEBI EC 1.5.1.3 (dihydrofolate reductase) inhibitors ChEBI EC 1.5.1.3 inhibitor ChEBI EC 1.5.1.3 inhibitors ChEBI NADPH-dihydrofolate reductase inhibitor ChEBI NADPH-dihydrofolate reductase inhibitors ChEBI dihydrofolate reductase (EC 1.5.1.3) inhibitor ChEBI dihydrofolate reductase (EC 1.5.1.3) inhibitors ChEBI dihydrofolate reductase inhibitor ChEBI dihydrofolate reductase inhibitors ChEBI dihydrofolic acid reductase inhibitor ChEBI dihydrofolic acid reductase inhibitors ChEBI dihydrofolic reductase inhibitor ChEBI dihydrofolic reductase inhibitors ChEBI folic acid reductase inhibitor ChEBI folic acid reductase inhibitors ChEBI folic reductase inhibitor ChEBI folic reductase inhibitors ChEBI tetrahydrofolate dehydrogenase inhibitor ChEBI tetrahydrofolate dehydrogenase inhibitors ChEBI A drug used to treat trichomonas infections. chebi_ontology antitrichomonal agent CHEBI:50685 antitrichomonal drug CHEBI:50685 antitrichomonal agent ChEBI A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. 0 C23H27N3O7 InChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1 DYKFCLLONBREIL-KVUCHLLUSA-N 457.47650 457.18490 [H][C@@]12Cc3c(ccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C CHEBI:44053 CHEBI:6939 Beilstein:3077644 CAS:10118-90-8 Chemspider:16735907 DrugBank:DB01017 Drug_Central:1813 HMDB:HMDB0015152 KEGG:C07225 KEGG:D05045 KNApSAcK:C00018686 LIPID_MAPS_instance:LMPK07000002 PDBeChem:MIY PMID:22330257 PMID:28709717 PMID:31630007 PMID:31719236 PMID:31733348 PMID:33568043 PMID:34232283 PMID:34636517 Patent:US3226436 Patent:WO2008104734 Reaxys:3077644 (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Minocycline chebi_ontology (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE 7-Dimethylamino-6-demethyl-6-deoxytetracycline minociclina minociclinum minocycline minomycin CHEBI:50694 minocycline CHEBI:50694 Beilstein:3077644 Beilstein CAS:10118-90-8 ChemIDplus CAS:10118-90-8 KEGG COMPOUND Drug_Central:1813 DrugCentral LIPID_MAPS_instance:LMPK07000002 LIPID MAPS PMID:22330257 Europe PMC PMID:28709717 Europe PMC PMID:31630007 Europe PMC PMID:31719236 Europe PMC PMID:31733348 Europe PMC PMID:33568043 Europe PMC PMID:34232283 Europe PMC PMID:34636517 Europe PMC Reaxys:3077644 Reaxys (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC Minocycline KEGG_COMPOUND (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE PDBeChem 7-Dimethylamino-6-demethyl-6-deoxytetracycline ChemIDplus minociclina DrugBank minociclinum DrugBank minocycline ChemIDplus minomycin ChEBI Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotic. It lacks the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized. chebi_ontology monobactams CHEBI:50695 monobactam CHEBI:50695 monobactams ChEBI An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129). chebi_ontology EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors EC 2.4.1.129 inhibitor EC 2.4.1.129 inhibitors PBP3 inhibitor PG-II inhibitor PG-II inhibitors [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors penicillin binding protein 1B inhibitor penicillin binding protein 1B inhibitors penicillin binding protein 3 inhibitor penicillin binding protein 3 inhibitors peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors peptidoglycan glycosyltransferase inhibitor peptidoglycan glycosyltransferase inhibitors peptidoglycan transglycosylase inhibitor peptidoglycan transglycosylase inhibitors undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors CHEBI:50696 EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor CHEBI:50696 EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors ChEBI EC 2.4.1.129 inhibitor ChEBI EC 2.4.1.129 inhibitors ChEBI PBP3 inhibitor ChEBI PG-II inhibitor ChEBI PG-II inhibitors ChEBI [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor ChEBI [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors ChEBI bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor ChEBI bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors ChEBI penicillin binding protein 1B inhibitor ChEBI penicillin binding protein 1B inhibitors ChEBI penicillin binding protein 3 inhibitor ChEBI penicillin binding protein 3 inhibitors ChEBI peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor ChEBI peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors ChEBI peptidoglycan glycosyltransferase inhibitor ChEBI peptidoglycan glycosyltransferase inhibitors ChEBI peptidoglycan transglycosylase inhibitor ChEBI peptidoglycan transglycosylase inhibitors ChEBI undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor ChEBI undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors ChEBI A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues. CHEBI:25679 CHEBI:35319 CHEBI:7758 KEGG:C00930 Oligosaccharide oligosaccharides chebi_ontology O-glycosylglycoside O-glycosylglycosides oligosacarido oligosacaridos CHEBI:50699 oligosaccharide CHEBI:50699 Oligosaccharide KEGG_COMPOUND oligosaccharides IUPAC O-glycosylglycoside ChEBI O-glycosylglycosides ChEBI oligosacarido ChEBI oligosacaridos IUPAC A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. chebi_ontology Dietary Supplement Food Supplementation Nutritional supplement CHEBI:50733 nutraceutical CHEBI:50733 Dietary Supplement ChEBI Food Supplementation ChEBI Nutritional supplement ChEBI A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. CHEBI:132229 CHEBI:50234 chebi_ontology DNA gyrase inhibitor DNA gyrase inhibitors DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors DNA topoisomerase (ATP-hydrolysing) inhibitor DNA topoisomerase (ATP-hydrolysing) inhibitors DNA topoisomerase II inhibitor DNA topoisomerase II inhibitors EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors EC 5.99.1.3 inhibitor EC 5.99.1.3 inhibitors inhibitor of type II topoisomerase inhibitors of type II topoisomerase topoisomerase II inhibitor topoisomerase II inhibitors topoisomerase-II inhibitor topoisomerase-II inhibitors type II DNA topoisomerase inhibitor type II DNA topoisomerase inhibitors CHEBI:50750 EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor CHEBI:50750 DNA gyrase inhibitor ChEBI DNA gyrase inhibitors ChEBI DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor ChEBI DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors ChEBI DNA topoisomerase (ATP-hydrolysing) inhibitor ChEBI DNA topoisomerase (ATP-hydrolysing) inhibitors ChEBI DNA topoisomerase II inhibitor ChEBI DNA topoisomerase II inhibitors ChEBI EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor ChEBI EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors ChEBI EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors ChEBI EC 5.99.1.3 inhibitor ChEBI EC 5.99.1.3 inhibitors ChEBI inhibitor of type II topoisomerase ChEBI inhibitors of type II topoisomerase ChEBI topoisomerase II inhibitor ChEBI topoisomerase II inhibitors ChEBI topoisomerase-II inhibitor ChEBI topoisomerase-II inhibitors ChEBI type II DNA topoisomerase inhibitor ChEBI type II DNA topoisomerase inhibitors ChEBI Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. 0 C22H24N2O8 InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1 JBIWCJUYHHGXTC-AKNGSSGZSA-N 444.43464 444.15327 [H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O CHEBI:42135 CHEBI:4713 Beilstein:3041790 CAS:564-25-0 Chemspider:10469369 DrugBank:DB00254 Drug_Central:961 HMDB:HMDB0014399 KEGG:C06973 KEGG:D07876 KNApSAcK:C00017127 LIPID_MAPS_instance:LMPK07000001 MetaCyc:CPD-19256 PDBeChem:DXT PMCID:PMC8464303 PMCID:PMC8466018 PMID:11477376 PMID:11850258 PMID:11891205 PMID:1650428 PMID:16651635 PMID:19630297 PMID:23698443 PMID:24134630 PMID:34128838 PMID:34228348 PMID:34318509 PMID:34338231 PMID:34355683 PMID:34551605 PMID:34577552 Patent:US3019260 Patent:US3200149 Reaxys:3041790 VSDB:1840 Wikipedia:Doxycycline (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Doxycycline chebi_ontology (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE 5-hydroxy-alpha-6-deoxytetracycline 6alpha-deoxy-5-oxytetracycline Doxycyclin Jenacyclin Supracyclin Vibramycin doxiciclina doxycycline doxycycline (anhydrous) doxycyclinum CHEBI:50845 doxycycline CHEBI:50845 Beilstein:3041790 Beilstein CAS:564-25-0 ChemIDplus CAS:564-25-0 KEGG COMPOUND Drug_Central:961 DrugCentral LIPID_MAPS_instance:LMPK07000001 LIPID MAPS PMCID:PMC8464303 Europe PMC PMCID:PMC8466018 Europe PMC PMID:11477376 Europe PMC PMID:11850258 Europe PMC PMID:11891205 Europe PMC PMID:1650428 Europe PMC PMID:16651635 Europe PMC PMID:19630297 Europe PMC PMID:23698443 Europe PMC PMID:24134630 Europe PMC PMID:34128838 Europe PMC PMID:34228348 Europe PMC PMID:34318509 Europe PMC PMID:34338231 Europe PMC PMID:34355683 Europe PMC PMID:34551605 Europe PMC PMID:34577552 Europe PMC Reaxys:3041790 Reaxys (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide IUPAC Doxycycline KEGG_COMPOUND (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE PDBeChem 5-hydroxy-alpha-6-deoxytetracycline ChemIDplus 6alpha-deoxy-5-oxytetracycline ChemIDplus Doxycyclin ChEBI Jenacyclin DrugBank Supracyclin DrugBank Vibramycin DrugBank doxiciclina ChemIDplus doxycycline KEGG_DRUG doxycycline (anhydrous) ChemIDplus doxycyclinum ChemIDplus Biologically active substance whose activity affects or plays a role in the functioning of the immune system. Wikipedia:Immunotherapy chebi_ontology Biomodulator Immune factor Immunologic factor Immunological factor immunomodulators CHEBI:50846 immunomodulator CHEBI:50846 Biomodulator ChEBI Immune factor ChEBI Immunologic factor ChEBI Immunological factor ChEBI immunomodulators ChEBI A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. Wikipedia:Immunologic_adjuvant chebi_ontology Immunoactivator Immunoadjuvant Immunologic adjuvant Immunopotentiator Immunostimulant CHEBI:50847 immunological adjuvant CHEBI:50847 Immunoactivator ChEBI Immunoadjuvant ChEBI Immunologic adjuvant ChEBI Immunopotentiator ChEBI Immunostimulant ChEBI Any molecular entity that contains carbon. CHEBI:25700 CHEBI:33244 chebi_ontology organic compounds organic entity organic molecular entities CHEBI:50860 organic molecular entity CHEBI:50860 organic compounds ChEBI organic entity ChEBI organic molecular entities ChEBI chebi_ontology azaarenes CHEBI:50893 azaarene CHEBI:50893 azaarenes ChEBI A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. Wikipedia:Genotoxicity chebi_ontology genotoxic agent genotoxic agents genotoxins CHEBI:50902 genotoxin CHEBI:50902 genotoxic agent ChEBI genotoxic agents ChEBI genotoxins ChEBI A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. chebi_ontology agente carcinogeno cancerigene cancerogene carcinogen carcinogene carcinogenic agents carcinogeno carcinogens CHEBI:50903 carcinogenic agent CHEBI:50903 agente carcinogeno ChEBI cancerigene ChEBI cancerogene ChEBI carcinogen ChEBI carcinogene ChEBI carcinogenic agents ChEBI carcinogeno ChEBI carcinogens ChEBI A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. Wikipedia:Allergen chebi_ontology alergeno allergene allergenic agent CHEBI:50904 allergen CHEBI:50904 alergeno ChEBI allergene ChEBI allergenic agent ChEBI A role is particular behaviour which a material entity may exhibit. chebi_ontology CHEBI:50906 role CHEBI:50906 A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. chebi_ontology agente hepatotoxico hepatotoxic agents hepatotoxicant hepatotoxicants hepatotoxin hepatotoxins hepatoxic agent hepatoxicant CHEBI:50908 hepatotoxic agent CHEBI:50908 agente hepatotoxico ChEBI hepatotoxic agents ChEBI hepatotoxicant ChEBI hepatotoxicants ChEBI hepatotoxin ChEBI hepatotoxins ChEBI hepatoxic agent ChEBI hepatoxicant ChEBI A role played by a chemical compound exihibiting itself through the ability to induce damage to the kidney in animals. chebi_ontology agente nefrotoxico nephrotoxicant CHEBI:50909 nephrotoxic agent CHEBI:50909 agente nefrotoxico ChEBI nephrotoxicant ChEBI A poison that interferes with the functions of the nervous system. CHEBI:50911 Wikipedia:Neurotoxin chebi_ontology agente neurotoxico nerve poison nerve poisons neurotoxic agent neurotoxic agents neurotoxicant neurotoxins CHEBI:50910 neurotoxin CHEBI:50910 agente neurotoxico ChEBI nerve poison ChEBI nerve poisons ChEBI neurotoxic agent ChEBI neurotoxic agents ChEBI neurotoxicant ChEBI neurotoxins ChEBI A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group. chebi_ontology primary amino compounds CHEBI:50994 primary amino compound CHEBI:50994 primary amino compounds ChEBI A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. chebi_ontology secondary amino compounds CHEBI:50995 secondary amino compound CHEBI:50995 secondary amino compounds ChEBI A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. chebi_ontology tertiary amino compounds CHEBI:50996 tertiary amino compound CHEBI:50996 tertiary amino compounds ChEBI An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections. 0 C4H4FN3O InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) XRECTZIEBJDKEO-UHFFFAOYSA-N 129.09250 129.03384 Nc1nc(=O)[nH]cc1F CAS:2022-85-7 DrugBank:DB01099 Drug_Central:1188 HMDB:HMDB0015231 KEGG:D00323 LINCS:LSM-5878 PDBeChem:1LD PMID:11519290 PMID:14871609 PMID:18731030 PMID:23576540 PMID:25649231 PMID:26201447 PMID:28166217 Patent:US2802005 Patent:US2945038 Patent:US3040026 Wikipedia:Flucytosine 4-amino-5-fluoropyrimidin-2(1H)-one chebi_ontology 5-FC 5-Fluorocystosine 5-Fluorocytosine Ancobon (TN) Ancotil flucytosina flucytosine flucytosinum CHEBI:5100 flucytosine CHEBI:5100 CAS:2022-85-7 ChemIDplus CAS:2022-85-7 KEGG DRUG Drug_Central:1188 DrugCentral PMID:11519290 Europe PMC PMID:14871609 Europe PMC PMID:18731030 Europe PMC PMID:23576540 Europe PMC PMID:25649231 Europe PMC PMID:26201447 Europe PMC PMID:28166217 Europe PMC 4-amino-5-fluoropyrimidin-2(1H)-one IUPAC 5-FC KEGG_DRUG 5-Fluorocystosine ChemIDplus 5-Fluorocytosine ChemIDplus Ancobon (TN) KEGG_DRUG Ancotil ChemIDplus flucytosina WHO_MedNet flucytosine WHO_MedNet flucytosinum WHO_MedNet A cyclic compound containing nine or more atoms as part of the cyclic system. Wikipedia:Macrocycle macrocycle chebi_ontology Makrocyclen Makrozyklen macrocycles makrocyclische Verbindungen makrozyklische Verbindungen CHEBI:51026 macrocycle CHEBI:51026 macrocycle IUPAC Makrocyclen ChEBI Makrozyklen ChEBI macrocycles ChEBI makrocyclische Verbindungen ChEBI makrozyklische Verbindungen ChEBI A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. chebi_ontology hormone receptor modulators CHEBI:51061 hormone receptor modulator CHEBI:51061 hormone receptor modulators ChEBI A role played by the molecular entity or part thereof within a chemical context. chebi_ontology CHEBI:51086 chemical role CHEBI:51086 chebi_ontology fluorescent dyes CHEBI:51121 fluorescent dye CHEBI:51121 fluorescent dyes ChEBI CHEBI:25556 CHEBI:7594 KEGG:C06061 chebi_ontology Nitrogenous compounds nitrogen compounds nitrogen molecular entities CHEBI:51143 nitrogen molecular entity CHEBI:51143 Nitrogenous compounds KEGG_COMPOUND nitrogen compounds ChEBI nitrogen molecular entities ChEBI nitrogen group chebi_ontology nitrogen groups nitrogen-containing group nitrogenous group CHEBI:51144 nitrogen group CHEBI:51144 nitrogen group ChEBI nitrogen groups ChEBI nitrogen-containing group ChEBI nitrogenous group ChEBI An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case. chebi_ontology dipolar compounds CHEBI:51151 dipolar compound CHEBI:51151 dipolar compounds ChEBI A penicillin in which the 6beta substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. 0 C15H23N3O3S InChI=1S/C15H23N3O3S/c1-15(2)11(14(20)21)18-12(19)10(13(18)22-15)16-9-17-7-5-3-4-6-8-17/h9-11,13H,3-8H2,1-2H3,(H,20,21)/t10-,11+,13-/m1/s1 BWWVAEOLVKTZFQ-NTZNESFSSA-N 325.42754 325.14601 [H]C(=N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@]12[H])N1CCCCCC1 Beilstein:1223657 CAS:32887-01-7 DrugBank:DB01163 LINCS:LSM-5528 Patent:DE2055531 Patent:US3957764 Reaxys:1223657 6beta-{[(azepan-1-yl)methylidene]amino}-2,2-dimethylpenam-3alpha-carboxylic acid chebi_ontology (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Coactin amdinocillin mecilinamo mecillinam mecillinamum penicillin HX CHEBI:51208 mecillinam CHEBI:51208 Beilstein:1223657 Beilstein CAS:32887-01-7 ChemIDplus Reaxys:1223657 Reaxys 6beta-{[(azepan-1-yl)methylidene]amino}-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC (2S,5R,6R)-6-[(azepan-1-ylmethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC Coactin DrugBank amdinocillin ChemIDplus mecilinamo ChemIDplus mecillinam ChemIDplus mecillinamum ChemIDplus penicillin HX ChemIDplus A fluorescent dye used to stain biological specimens. chebi_ontology fluorochromes CHEBI:51217 fluorochrome CHEBI:51217 fluorochromes ChEBI -1 C16H18N3O5S InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/p-1/t9-,10-,11+,14-/m1/s1 LSQZJLSUYDQPKJ-NJBDSQKTSA-M 364.39734 364.09727 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccc(O)cc1)C([O-])=O Beilstein:6077298 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate CHEBI:51256 amoxicillin(1-) CHEBI:51256 Beilstein:6077298 Beilstein 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives. chebi_ontology CHEBI:51269 acenes CHEBI:51269 Compounds containing a tetracene skeleton. chebi_ontology naphthacenes CHEBI:51270 tetracenes CHEBI:51270 naphthacenes ChEBI Compounds of general formula RR'NC(=S)NR''R'''. chebi_ontology CHEBI:51276 thioureas CHEBI:51276 A dinitrile is a compound containing two nitrile groups. dinitrile chebi_ontology dinitriles CHEBI:51308 dinitrile CHEBI:51308 dinitrile ChEBI dinitriles ChEBI Sulfate salts where the cation is a metal ion. chebi_ontology metal sulfates CHEBI:51336 metal sulfate CHEBI:51336 metal sulfates ChEBI chebi_ontology organic sulfate salts CHEBI:51337 organic sulfate salt CHEBI:51337 organic sulfate salts ChEBI -1 C16H17N2O4S InChI=1S/C16H18N2O4S/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/p-1/t11-,12+,14-/m1/s1 JGSARLDLIJGVTE-MBNYWOFBSA-M 333.38326 333.09145 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc1ccccc1)C([O-])=O Beilstein:3915298 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate penicillin G CHEBI:51354 benzylpenicillin(1-) CHEBI:51354 Beilstein:3915298 Beilstein 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate IUPAC (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC penicillin G UniProt Any anion formed by loss of a proton from the carboxy group of a penicillin. -1 C9H10N2O4SR 242.25200 242.03613 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC([*])=O)C([O-])=O CHEBI:58108 chebi_ontology a penicillin penicillin anion penicillin anions CHEBI:51356 penicillinate anion CHEBI:51356 a penicillin UniProt penicillin anion ChEBI penicillin anions ChEBI A drug that binds to and activates gamma-aminobutyric acid receptors. chebi_ontology GABA agonists GABA receptor agonist GABA receptor agonists gamma-aminobutyric acid receptor agonist gamma-aminobutyric acid receptor agonists CHEBI:51373 GABA agonist CHEBI:51373 GABA agonists ChEBI GABA receptor agonist ChEBI GABA receptor agonists ChEBI gamma-aminobutyric acid receptor agonist ChEBI gamma-aminobutyric acid receptor agonists ChEBI A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. chebi_ontology CHEBI:51374 GABA agent CHEBI:51374 A benzene substituted with two amino groups. 0 C6H8N2 108.141 108.06875 benzenediamine chebi_ontology diaminobenzene CHEBI:51402 phenylenediamine CHEBI:51402 benzenediamine IUPAC diaminobenzene ChEBI Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s). chebi_ontology organodiyl groups CHEBI:51422 organodiyl group CHEBI:51422 organodiyl groups ChEBI chebi_ontology CHEBI:51446 organic divalent group CHEBI:51446 chebi_ontology CHEBI:51447 organic univalent group CHEBI:51447 Cyclopropane and its derivatives formed by substitution. chebi_ontology CHEBI:51454 cyclopropanes CHEBI:51454 Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups. chebi_ontology methoxybenzene CHEBI:51683 methoxybenzenes CHEBI:51683 methoxybenzene ChEBI An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position. 0 C3OR4 52.03150 51.99491 [*]\C([*])=C(\[*])C([*])=O Wikipedia:Enone chebi_ontology enones CHEBI:51689 enone CHEBI:51689 enones ChEBI An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position. 0 C3O2R4 68.03090 67.98983 [*]\C([*])=C(\[*])C(=O)O[*] chebi_ontology enoate enoate esters enoates CHEBI:51702 enoate ester CHEBI:51702 enoate ChEBI enoate esters ChEBI enoates ChEBI A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. chebi_ontology alpha,beta-unsaturated ketones CHEBI:51721 alpha,beta-unsaturated ketone CHEBI:51721 alpha,beta-unsaturated ketones ChEBI A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. chebi_ontology alpha,beta-unsaturated carboxylic esters CHEBI:51737 alpha,beta-unsaturated carboxylic ester CHEBI:51737 alpha,beta-unsaturated carboxylic esters ChEBI A monocarboxylic amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) or R(1)C#C-C(=O)NR(2)R(3) in which the amide C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. chebi_ontology alpha,beta-unsaturated amide alpha,beta-unsaturated carboxamide alpha,beta-unsaturated monocarboxylic acid amide alpha,beta-unsaturated monocarboxylic acid amides CHEBI:51750 alpha,beta-unsaturated carboxylic acid amide CHEBI:51750 alpha,beta-unsaturated amide ChEBI alpha,beta-unsaturated carboxamide ChEBI alpha,beta-unsaturated monocarboxylic acid amide ChEBI alpha,beta-unsaturated monocarboxylic acid amides ChEBI An alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position. 0 C3NOR5 66.03820 65.99799 [*]\C([*])=C(\[*])C(=O)N([*])[*] chebi_ontology enamides CHEBI:51751 enamide CHEBI:51751 enamides ChEBI -2 C15H14N2O6S2 InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/p-2/t7-,8-,9+,12-/m1/s1 OHKOGUYZJXTSFX-KZFFXBSXSA-L 382.41354 382.03043 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@]([H])(C([O-])=O)c1ccsc1)C([O-])=O Beilstein:5780670 6beta-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate CHEBI:51811 ticarcillin(2-) CHEBI:51811 Beilstein:5780670 Beilstein 6beta-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC A ketone of formula RC(=O)CH3 (R =/= H). chebi_ontology methyl ketones CHEBI:51867 methyl ketone CHEBI:51867 methyl ketones ChEBI -2 C17H16N2O6S InChI=1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/p-2/t9?,10-,11+,14-/m1/s1 FPPNZSSZRUTDAP-UWFZAAFLSA-L 376.38482 376.07400 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(C([O-])=O)c1ccccc1)C([O-])=O Beilstein:5394984 6beta-(2-carboxylato-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-{[carboxylato(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate CHEBI:51897 carbenicillin(2-) CHEBI:51897 Beilstein:5394984 Beilstein 6beta-(2-carboxylato-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-{[carboxylato(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. 0 C8H7N3O5 InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2 PLHJDBGFXBMTGZ-UHFFFAOYSA-N 225.15830 225.03857 [O-][N+](=O)c1ccc(C=NN2CCOC2=O)o1 Beilstein:384794 CAS:67-45-8 DrugBank:DB00614 Drug_Central:1257 HMDB:HMDB0014752 KEGG:C07999 KEGG:D00830 LINCS:LSM-6543 PMID:10735922 PMID:14500876 PMID:15666977 PMID:16225499 PMID:17422910 PMID:21817887 PMID:22024820 PMID:22177019 PMID:22221615 PMID:22226073 PMID:22228494 PMID:22240115 PMID:22249086 PMID:22260837 PMID:22362365 PMID:22759325 PMID:22829809 PMID:22868168 PMID:22877600 PMID:23112108 PMID:23151414 PMID:23153221 PMID:23261742 PMID:23279258 PMID:23285433 PMID:23376004 PMID:23403439 PMID:23418857 PMID:23429422 PMID:23461927 Patent:GB735136 Patent:US2742462 Patent:US2759931 Patent:US2927110 Reaxys:384794 Wikipedia:Furazolidone 3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one Furazolidone chebi_ontology 3-(5'-Nitrofurfuralamino)-2-oxazolidone 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone 3-[(5-Nitrofurylidene)amino]-2-oxazolidone 3-{[(5-Nitro-2-furanyl)methylene]amino}-2-oxazolidinone 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine FZL Furazolidona Furazolidonum Furoxone N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one Nitrofurazolidone Nitrofurazolidonum furazolidone CHEBI:5195 furazolidone CHEBI:5195 Beilstein:384794 Beilstein CAS:67-45-8 ChemIDplus CAS:67-45-8 DrugBank CAS:67-45-8 KEGG COMPOUND CAS:67-45-8 KEGG DRUG CAS:67-45-8 NIST Chemistry WebBook Drug_Central:1257 DrugCentral PMID:10735922 Europe PMC PMID:14500876 Europe PMC PMID:15666977 Europe PMC PMID:16225499 Europe PMC PMID:17422910 Europe PMC PMID:21817887 Europe PMC PMID:22024820 Europe PMC PMID:22177019 Europe PMC PMID:22221615 Europe PMC PMID:22226073 Europe PMC PMID:22228494 Europe PMC PMID:22240115 Europe PMC PMID:22249086 Europe PMC PMID:22260837 Europe PMC PMID:22362365 Europe PMC PMID:22759325 Europe PMC PMID:22829809 Europe PMC PMID:22868168 Europe PMC PMID:22877600 Europe PMC PMID:23112108 Europe PMC PMID:23151414 Europe PMC PMID:23153221 Europe PMC PMID:23261742 Europe PMC PMID:23279258 Europe PMC PMID:23285433 Europe PMC PMID:23376004 Europe PMC PMID:23403439 Europe PMC PMID:23418857 Europe PMC PMID:23429422 Europe PMC PMID:23461927 Europe PMC Reaxys:384794 Reaxys 3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one IUPAC Furazolidone KEGG_COMPOUND 3-(5'-Nitrofurfuralamino)-2-oxazolidone ChemIDplus 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone ChemIDplus 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone ChemIDplus 3-[(5-Nitrofurylidene)amino]-2-oxazolidone ChemIDplus 3-{[(5-Nitro-2-furanyl)methylene]amino}-2-oxazolidinone ChemIDplus 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine NIST_Chemistry_WebBook FZL ChEBI Furazolidona ChemIDplus Furazolidonum ChemIDplus Furoxone KEGG_DRUG N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone ChemIDplus N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one ChemIDplus N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one NIST_Chemistry_WebBook Nitrofurazolidone DrugBank Nitrofurazolidonum DrugBank furazolidone WHO_MedNet chebi_ontology organic polycyclic compounds CHEBI:51958 organic polycyclic compound CHEBI:51958 organic polycyclic compounds ChEBI chebi_ontology organic tricyclic compounds CHEBI:51959 organic tricyclic compound CHEBI:51959 organic tricyclic compounds ChEBI -1 C19H16Cl2N3O5S InChI=1S/C19H17Cl2N3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/p-1/t13-,14+,17-/m1/s1 YFAGHNZHGGCZAX-JKIFEVAISA-M 469.31800 468.01932 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1c(Cl)cccc1Cl)C([O-])=O Beilstein:4773354 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate CHEBI:52017 dicloxacillin(1-) CHEBI:52017 Beilstein:4773354 Beilstein 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC -1 C17H19N2O6S InChI=1S/C17H20N2O6S/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23)/p-1/t11-,12+,15-/m1/s1 RJQXTJLFIWVMTO-TYNCELHUSA-M 379.40800 379.09693 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(OC)cccc1OC)C([O-])=O Beilstein:4770226 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 6beta-(2,6-dimethoxybenzamido)penicillanate CHEBI:52064 methicillin(1-) CHEBI:52064 Beilstein:4770226 Beilstein 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate IUPAC 6beta-(2,6-dimethoxybenzamido)penicillanate ChEBI An organic anion that is the conjugate base of methanol. -1 CH3O InChI=1S/CH3O/c1-2/h1H3/q-1 NBTOZLQBSIZIKS-UHFFFAOYSA-N 31.03390 31.01894 C[O-] Reaxys:1839368 chebi_ontology methoxide ion CHEBI:52090 methoxide CHEBI:52090 Reaxys:1839368 Reaxys methoxide ion ChEBI -1 C19H18N3O5S InChI=1S/C19H19N3O5S/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26)/p-1/t13-,14+,17-/m1/s1 UWYHMGVUTGAWSP-JKIFEVAISA-M 400.42800 400.09727 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1ccccc1)C([O-])=O Beilstein:4278284 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylate chebi_ontology 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanate CHEBI:52132 oxacillin(1-) CHEBI:52132 Beilstein:4278284 Beilstein 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylate IUPAC 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanate ChEBI A biological role played by the molecular entity or part thereof within a biochemical context. chebi_ontology CHEBI:52206 biochemical role CHEBI:52206 chebi_ontology CHEBI:52208 biophysical role CHEBI:52208 A role played by the molecular entity or part thereof which causes the development of a pathological process. chebi_ontology etiopathogenetic agent etiopathogenetic role CHEBI:52209 aetiopathogenetic role CHEBI:52209 etiopathogenetic agent ChEBI etiopathogenetic role ChEBI A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. chebi_ontology CHEBI:52210 pharmacological role CHEBI:52210 chebi_ontology CHEBI:52211 physiological role CHEBI:52211 Any molecule or ion capable of binding to a central metal atom to form coordination complexes. Wikipedia:Ligand chebi_ontology ligands CHEBI:52214 ligand CHEBI:52214 ligands ChEBI Any substance introduced into a living organism with therapeutic or diagnostic purpose. CHEBI:33293 CHEBI:33294 chebi_ontology farmaco medicament pharmaceuticals CHEBI:52217 pharmaceutical CHEBI:52217 farmaco ChEBI medicament ChEBI pharmaceuticals ChEBI An ortho-fused compound in which at least one of the rings contains at least one heteroatom. chebi_ontology ortho-fused heteroarenes CHEBI:52362 ortho-fused heteroarene CHEBI:52362 ortho-fused heteroarenes ChEBI A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group. chebi_ontology oxyketones CHEBI:52395 oxyketone CHEBI:52395 oxyketones ChEBI An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom. chebi_ontology alpha-oxyketones CHEBI:52396 alpha-oxyketone CHEBI:52396 alpha-oxyketones ChEBI -1 C23H26N5O7S InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/p-1/t13-,14-,15+,20-/m1/s1 IVBHGBMCVLDMKU-GXNBUGAJSA-M 516.54700 516.15584 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)c1ccccc1)C([O-])=O Beilstein:5369991 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology CHEBI:52433 piperacillin(1-) CHEBI:52433 Beilstein:5369991 Beilstein 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate IUPAC chebi_ontology cephalosporin carboxylate cephalosporin carboxylates cephalosporin carboxylic acid anions cephalosporincarboxylate CHEBI:52440 cephalosporin carboxylic acid anion CHEBI:52440 cephalosporin carboxylate ChEBI cephalosporin carboxylates ChEBI cephalosporin carboxylic acid anions ChEBI cephalosporincarboxylate ChEBI A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide. Beilstein:8188972 CAS:8018-01-7 KEGG:C15225 PMID:22369882 PMID:23024109 PMID:23103283 PMID:23242257 PMID:23436297 PMID:23542819 PMID:24041529 PMID:24360436 PMID:24499300 PMID:24518345 PMID:24530807 PMID:24764117 Pesticides:mancozeb Reaxys:13196351 Reaxys:8188972 Wikipedia:Mancozeb Mancozeb chebi_ontology Dithane Karamate Mancofol Mancomix Manzate Manzeb Manzin Novozir Othane Penncozeb ethylenebis(dithiocarbamic acid) manganese zinc complex CHEBI:52492 mancozeb CHEBI:52492 Beilstein:8188972 Beilstein CAS:8018-01-7 ChemIDplus CAS:8018-01-7 KEGG COMPOUND PMID:22369882 Europe PMC PMID:23024109 Europe PMC PMID:23103283 Europe PMC PMID:23242257 Europe PMC PMID:23436297 Europe PMC PMID:23542819 Europe PMC PMID:24041529 Europe PMC PMID:24360436 Europe PMC PMID:24499300 Europe PMC PMID:24518345 Europe PMC PMID:24530807 Europe PMC PMID:24764117 Europe PMC Pesticides:mancozeb Alan Wood's Pesticides Reaxys:13196351 Reaxys Reaxys:8188972 Reaxys Mancozeb KEGG_COMPOUND Dithane ChemIDplus Karamate ChemIDplus Mancofol ChemIDplus Mancomix ChemIDplus Manzate ChemIDplus Manzeb ChemIDplus Manzin ChemIDplus Novozir ChemIDplus Othane ChemIDplus Penncozeb ChemIDplus ethylenebis(dithiocarbamic acid) manganese zinc complex ChemIDplus A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab. 0 (C4H6MnN2S4)n Beilstein:3747585 CAS:12427-38-2 KEGG:C15231 PMID:18605226 PMID:20188092 PMID:20430411 PMID:21314462 PMID:21402726 PMID:23764462 PMID:24936438 PMID:25275677 PPDB:426 Pesticides:maneb Reaxys:3747585 Wikipedia:Maneb [{2-[(sulfanylcarbothioyl)amino]ethyl}carbamodithioato(2-)-kappa(2)S,S']manganese chebi_ontology manganese ethane-1,2-diyldicarbamodithioate CHEBI:52497 maneb CHEBI:52497 Beilstein:3747585 Beilstein CAS:12427-38-2 ChemIDplus CAS:12427-38-2 KEGG COMPOUND PMID:18605226 Europe PMC PMID:20188092 Europe PMC PMID:20430411 Europe PMC PMID:21314462 Europe PMC PMID:21402726 Europe PMC PMID:23764462 Europe PMC PMID:24936438 Europe PMC PMID:25275677 Europe PMC Pesticides:maneb Alan Wood's Pesticides Reaxys:3747585 Reaxys [{2-[(sulfanylcarbothioyl)amino]ethyl}carbamodithioato(2-)-kappa(2)S,S']manganese IUPAC manganese ethane-1,2-diyldicarbamodithioate IUPAC A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU. 0 C4H6N2S4Zn InChI=1S/C4H8N2S4.Zn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2 AMHNZOICSMBGDH-UHFFFAOYSA-L 275.77300 273.87052 [Zn++].[S-]C(=S)NCCNC([S-])=S Beilstein:4165797 CAS:12122-67-7 KEGG:C15232 PMID:22155123 PMID:23871785 PMID:465777 PPDB:683 Patent:CN1648120 Patent:US2690448 Pesticides:zineb Reaxys:4165797 Wikipedia:Zineb [{2-[(sulfanylcarbothioyl)amino]ethyl}carbamodithioato(2-)-kappa(2)S,S']zinc chebi_ontology zinc ethane-1,2-diyldicarbamodithioate CHEBI:52498 zineb CHEBI:52498 Beilstein:4165797 Beilstein CAS:12122-67-7 ChemIDplus CAS:12122-67-7 KEGG COMPOUND PMID:22155123 Europe PMC PMID:23871785 Europe PMC PMID:465777 Europe PMC Pesticides:zineb Alan Wood's Pesticides Reaxys:4165797 Reaxys [{2-[(sulfanylcarbothioyl)amino]ethyl}carbamodithioato(2-)-kappa(2)S,S']zinc IUPAC zinc ethane-1,2-diyldicarbamodithioate IUPAC An antifungal metabolite of Sordaria araneosa that inhibits protein synthesis. It has a tetracyclic diterpene glycoside structure. 0 C27H40O8 InChI=1S/C27H40O8/c1-13(2)19-8-16-9-25(11-28)18-7-6-14(3)17(18)10-26(16,27(19,25)24(31)32)12-34-23-21(30)20(29)22(33-5)15(4)35-23/h8,11,13-18,20-23,29-30H,6-7,9-10,12H2,1-5H3,(H,31,32)/t14-,15-,16+,17-,18-,20+,21+,22-,23-,25+,26+,27+/m1/s1 OGGVRVMISBQNMQ-YPBSLCSMSA-N 492.603 492.27232 [C@@]12([C@]3([C@](C[C@@]1([C@]4([H])CC[C@H]([C@]4(C3)[H])C)C=O)(C=C2C(C)C)[H])CO[C@]5([C@H]([C@@H]([C@@H]([C@H](O5)C)OC)O)O)[H])C(O)=O CAS:11076-17-8 (1R,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-beta-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)-4,4a,5,6,7,7a,8,8a-octahydro-1,4-methano-s-indacene-3a(1H)-carboxylic acid chebi_ontology Antibiotic SL-2266 sordarin B CHEBI:52549 sordarin CHEBI:52549 CAS:11076-17-8 ChemIDplus CAS:11076-17-8 SUBMITTER (1R,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-beta-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)-4,4a,5,6,7,7a,8,8a-octahydro-1,4-methano-s-indacene-3a(1H)-carboxylic acid IUPAC Antibiotic SL-2266 ChemIDplus sordarin B SUBMITTER A diterpenoid with a tetracyclic skeleton. chebi_ontology tetracyclic diterpenoids CHEBI:52557 tetracyclic diterpenoid CHEBI:52557 tetracyclic diterpenoids ChEBI A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17. 0 C33H48O6 InChI=1S/C33H48O6/c1-9-28(14-15-29-24(5)13-16-31(36)39-29)19-22(3)12-10-11-21(2)17-25(6)32(37)27(8)33(38)26(7)18-23(4)20-30(34)35/h10-11,13-17,19-20,22,24-27,29,33,38H,9,12,18H2,1-8H3,(H,34,35)/b11-10+,15-14+,21-17+,23-20+,28-19-/t22-,24+,25-,26+,27-,29+,33-/m1/s1 YACHGFWEQXFSBS-XYERBDPFSA-N 540.73060 540.34509 CC\C(\C=C\[C@@H]1OC(=O)C=C[C@@H]1C)=C\[C@H](C)C\C=C\C(\C)=C\[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C\C(O)=O Beilstein:7958583 Beilstein:8299374 CAS:87081-35-4 PMID:10421839 PMID:10430904 PMID:11134317 PMID:12468543 PMID:16964287 PMID:6874586 PMID:9683540 Reaxys:8299374 (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid chebi_ontology ATS 1287B Antibiotic CI 940 Antibiotic CL 1957A Antibiotic PD 114720 LMB antibiotic ATS 1287B CHEBI:52646 leptomycin B CHEBI:52646 Beilstein:7958583 Beilstein Beilstein:8299374 Beilstein CAS:87081-35-4 ChemIDplus PMID:10421839 Europe PMC PMID:10430904 Europe PMC PMID:11134317 Europe PMC PMID:12468543 Europe PMC PMID:16964287 Europe PMC PMID:6874586 Europe PMC PMID:9683540 Europe PMC Reaxys:8299374 Reaxys (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid IUPAC ATS 1287B ChEBI Antibiotic CI 940 ChemIDplus Antibiotic CL 1957A ChemIDplus Antibiotic PD 114720 ChEBI LMB ChEBI antibiotic ATS 1287B ChEBI A complex, very long chain, polyunsaturated fatty acid whose core structure comprises 8-oxononadeca-2,10,12,16,18-pentaenoic acid having methyl substituents at positions 3, 5, 7, 9, 11 and 15 and a 3,6-dihydropyran-6-one-2-yl group at position 19. CAS:88026-21-5 PMID:6874586 chebi_ontology leptomycins CHEBI:52651 leptomycin CHEBI:52651 CAS:88026-21-5 ChemIDplus PMID:6874586 Europe PMC leptomycins ChEBI A drug that blocks the action of proteasomes, cellular complexes that break down proteins. chebi_ontology proteasome inhibitors CHEBI:52726 proteasome inhibitor CHEBI:52726 proteasome inhibitors ChEBI A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes. 0 C19H22FN3O4 InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) XUBOMFCQGDBHNK-UHFFFAOYSA-N 375.39410 375.15943 COc1c(N2CCNC(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1 CHEBI:101712 Beilstein:7445861 CAS:112811-59-3 DrugBank:DB01044 Drug_Central:1280 Gmelin:2281206 KEGG:C07661 KEGG:D08011 LINCS:LSM-5139 PMID:10737746 PMID:12190308 PMID:12620077 PMID:12873512 PMID:12904069 PMID:15125930 PMID:15745831 PMID:15911273 PMID:16078842 PMID:16337791 PMID:16554151 PMID:16759086 PMID:17043111 PMID:17043131 PMID:17064062 PMID:17116666 PMID:17116668 PMID:17157008 PMID:17220425 PMID:17261623 PMID:17276057 PMID:17296740 PMID:17325221 PMID:17387152 PMID:17804222 PMID:17933535 PMID:17960928 PMID:18078756 PMID:18304818 PMID:26963935 PMID:7473575 Patent:EP230295 Patent:US4980470 Reaxys:7445861 Wikipedia:Gatifloxacin 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chebi_ontology 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid AM 1155 gatifloxacin gatifloxacine gatifloxacino gatifloxacinum CHEBI:5280 gatifloxacin CHEBI:5280 Beilstein:7445861 Beilstein CAS:112811-59-3 ChemIDplus CAS:112811-59-3 DrugBank CAS:112811-59-3 KEGG COMPOUND Drug_Central:1280 DrugCentral Gmelin:2281206 Gmelin PMID:10737746 ChEMBL PMID:12190308 ChEMBL PMID:12620077 ChEMBL PMID:12873512 ChEMBL PMID:12904069 ChEMBL PMID:15125930 ChEMBL PMID:15745831 ChEMBL PMID:15911273 ChEMBL PMID:16078842 ChEMBL PMID:16337791 ChEMBL PMID:16554151 ChEMBL PMID:16759086 ChEMBL PMID:17043111 ChEMBL PMID:17043131 ChEMBL PMID:17064062 ChEMBL PMID:17116666 ChEMBL PMID:17116668 ChEMBL PMID:17157008 ChEMBL PMID:17220425 ChEMBL PMID:17261623 ChEMBL PMID:17276057 ChEMBL PMID:17296740 ChEMBL PMID:17325221 ChEMBL PMID:17387152 ChEMBL PMID:17804222 ChEMBL PMID:17933535 ChEMBL PMID:17960928 ChEMBL PMID:18078756 ChEMBL PMID:18304818 ChEMBL PMID:26963935 Europe PMC PMID:7473575 ChEMBL Reaxys:7445861 Reaxys 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid IUPAC 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ChemIDplus 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ChEMBL AM 1155 KEGG_COMPOUND gatifloxacin KEGG_DRUG gatifloxacine WHO_MedNet gatifloxacino WHO_MedNet gatifloxacinum WHO_MedNet A cyclic macromolecule containing one or more nitrogen atoms in place of carbon either as the divalent group NH for the group CH2 or a single trivalent nitrogen atom for the group CH. chebi_ontology aza macrocycle aza macrocyclic compound aza-macrocycle azamacrocycles CHEBI:52898 azamacrocycle CHEBI:52898 aza macrocycle SUBMITTER aza macrocyclic compound SUBMITTER aza-macrocycle SUBMITTER azamacrocycles ChEBI The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. chebi_ontology antigenic determinant epitope function epitope role CHEBI:53000 epitope CHEBI:53000 antigenic determinant ChEBI epitope function ChEBI epitope role ChEBI A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. chebi_ontology topoisomerase IV inhibitors CHEBI:53559 topoisomerase IV inhibitor CHEBI:53559 topoisomerase IV inhibitors ChEBI An alpha-D-glucoside deoxygenated at C-2 and C-6. chebi_ontology CHEBI:53628 2,6-dideoxy-alpha-D-glucoside CHEBI:53628 A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine C. 0 C23H46N6O13 InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 PGBHMTALBVVCIT-VZXHOKRSSA-N 614.64370 614.31229 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O CAS:66-86-4 KEGG:C15652 PMID:13355298 PMID:17206729 PMID:19382560 PMID:19713992 PMID:4907002 PMID:5137586 PMID:804015 PMID:849920 PMID:9682160 Reaxys:101620 (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside chebi_ontology CHEBI:53634 neomycin C CHEBI:53634 CAS:66-86-4 ChemIDplus CAS:66-86-4 KEGG COMPOUND PMID:13355298 Europe PMC PMID:17206729 Europe PMC PMID:19382560 Europe PMC PMID:19713992 Europe PMC PMID:4907002 Europe PMC PMID:5137586 Europe PMC PMID:804015 Europe PMC PMID:849920 Europe PMC PMID:9682160 Europe PMC Reaxys:101620 Reaxys (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside IUPAC A cephalosporin carboxylic acid anion having methoxy, 2-thienylacetamido and carbamoyloxymethyl side-groups, formed by proton loss from the carboxy group of the semisynthetic cephamycin antibiotic cefoxitin. -1 C16H16N3O7S2 InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/p-1/t14-,16+/m1/s1 WZOZEZRFJCJXNZ-ZBFHGGJFSA-M 426.44400 426.04352 [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C([O-])=O Beilstein:4045290 Reaxys:4045290 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(2-thienylacetyl)amino]-3,4-didehydrocepham-4-carboxylate chebi_ontology (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CHEBI:53655 cefoxitin(1-) CHEBI:53655 Beilstein:4045290 Beilstein Reaxys:4045290 Reaxys 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(2-thienylacetyl)amino]-3,4-didehydrocepham-4-carboxylate IUPAC (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC A cephalosporin carboxylic acid anion having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups, formed by proton loss from the carboxy group of cefazolin. -1 C14H13N8O4S3 InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/p-1/t9-,12-/m1/s1 MLYYVTUWGNIJIB-BXKDBHETSA-M 453.49900 453.02274 [H][C@]12SCC(CSc3nnc(C)s3)=C(N1C(=O)[C@H]2NC(=O)Cn1cnnn1)C([O-])=O Beilstein:4241223 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylate chebi_ontology (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CHEBI:53657 cefazolin(1-) CHEBI:53657 Beilstein:4241223 Beilstein 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylate IUPAC (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC A cephalosporin carboxylis acid anion having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups, formed by proton loss from the carboxy group of ceftriaxone. -1 C18H17N8O7S3 InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/p-1/b24-8-/t9-,15-/m1/s1 VAAUVRVFOQPIGI-SPQHTLEESA-M 553.57200 553.03878 [H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C([O-])=O Beilstein:7066100 MetaCyc:CPD-12294 Reaxys:7066100 (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylate chebi_ontology CHEBI:53658 ceftriaxone(1-) CHEBI:53658 Beilstein:7066100 Beilstein Reaxys:7066100 Reaxys (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylate IUPAC An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. 0 C26H56N10 InChI=1S/C26H56N10/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36) LFVVNPBBFUSSHL-UHFFFAOYSA-N 508.78980 508.46894 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC Beilstein:2404807 CAS:22573-93-9 Drug_Central:113 LINCS:LSM-4432 PMID:10848923 PMID:22152633 PMID:22495680 PMID:23492900 PMID:23970139 PMID:24139264 PMID:265389 PMID:381628 Patent:CN101624356 Reaxys:2404807 Wikipedia:Alexidine N,N''''-hexane-1,6-diylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)] chebi_ontology 1,1'-Hexamethylenebis(5-(2-ethylhexyl)biguanide) N,N'-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide alexidina alexidine alexidinum bisguadine CHEBI:53661 alexidine CHEBI:53661 Beilstein:2404807 Beilstein CAS:22573-93-9 ChemIDplus Drug_Central:113 DrugCentral PMID:10848923 Europe PMC PMID:22152633 Europe PMC PMID:22495680 Europe PMC PMID:23492900 Europe PMC PMID:23970139 Europe PMC PMID:24139264 Europe PMC PMID:265389 Europe PMC PMID:381628 Europe PMC Reaxys:2404807 Reaxys N,N''''-hexane-1,6-diylbis[N'-(2-ethylhexyl)(imidodicarbonimidic diamide)] IUPAC 1,1'-Hexamethylenebis(5-(2-ethylhexyl)biguanide) ChemIDplus N,N'-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide ChemIDplus alexidina ChemIDplus alexidine ChemIDplus alexidinum ChemIDplus bisguadine ChEBI A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton. CHEBI:35529 chebi_ontology CHEBI:53662 biguanides CHEBI:53662 Any organic heterotricyclic compound based on a skeleton comprised of an oxazine ring fused onto a quinoline system. chebi_ontology oxazinoquinolines CHEBI:53665 oxazinoquinoline CHEBI:53665 oxazinoquinolines ChEBI A cephalosporin carboxylic acid anion having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, formed by proton loss from the carboxy group of the cephalosporin cefotaxime. -1 C16H16N5O7S2 InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/p-1/b20-9-/t10-,14-/m1/s1 GPRBEKHLDVQUJE-QSWIMTSFSA-M 454.45800 454.04966 [H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C([O-])=O Beilstein:8174207 Gmelin:1794119 Reaxys:8174207 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylate chebi_ontology (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CHEBI:53670 cefotaxime(1-) CHEBI:53670 Beilstein:8174207 Beilstein Gmelin:1794119 Gmelin Reaxys:8174207 Reaxys 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylate IUPAC (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC A cephalosporin carboxylic acid anion formed by proton loss from the carboxy group of ceftazidime, a cephalosporin having 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino and 3-pyridinium-1-ylmethyl side-groups. -1 C22H21N6O7S2 InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/p-1/b26-13-/t14-,18-/m1/s1 ORFOPKXBNMVMKC-DWVKKRMSSA-M 545.56800 545.09186 [H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C([O-])=O)\c1csc(N)n1)C([O-])=O Beilstein:6630563 Gmelin:1795652 Reaxys:6630563 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxylatopropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate chebi_ontology (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxylatopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CHEBI:53676 ceftazidime(1-) CHEBI:53676 Beilstein:6630563 Beilstein Gmelin:1795652 Gmelin Reaxys:6630563 Reaxys 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxylatopropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate IUPAC (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxylatopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi. 0 C13H14N2O4S2 InChI=1S/C13H14N2O4S2/c1-14-10(18)12-5-7-3-2-4-8(17)9(7)15(12)11(19)13(14,6-16)21-20-12/h2-4,8-9,16-17H,5-6H2,1H3/t8-,9-,12+,13+/m0/s1 FIVPIPIDMRVLAY-RBJBARPLSA-N 326.39100 326.03950 [H][C@@]12[C@@H](O)C=CC=C1C[C@@]13SS[C@@](CO)(N(C)C1=O)C(=O)N23 Beilstein:50675 CAS:67-99-2 KEGG:C10595 KNApSAcK:C00002340 PMID:16020669 PMID:23832115 PMID:24368570 PMID:24847038 PMID:25062268 PMID:25494483 PMID:25766143 PMID:25816130 PMID:25982450 PPDB:2793 Reaxys:50675 Wikipedia:Gliotoxin (3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione chebi_ontology Aspergillin CHEBI:5385 gliotoxin CHEBI:5385 Beilstein:50675 ChemIDplus CAS:67-99-2 ChemIDplus CAS:67-99-2 KEGG COMPOUND PMID:16020669 Europe PMC PMID:23832115 Europe PMC PMID:24368570 Europe PMC PMID:24847038 Europe PMC PMID:25062268 Europe PMC PMID:25494483 Europe PMC PMID:25766143 Europe PMC PMID:25816130 Europe PMC PMID:25982450 Europe PMC Reaxys:50675 Reaxys (3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione IUPAC Aspergillin ChemIDplus A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6. 0 C5H7NO2 InChI=1S/C5H7NO2/c7-4-2-1-3-5(8)6-4/h1-3H2,(H,6,7,8) KNCYXPMJDCCGSJ-UHFFFAOYSA-N 113.11460 113.04768 O=C1CCCC(=O)N1 Beilstein:110052 CAS:1121-89-7 Gmelin:971891 KEGG:C07275 PMID:10783491 Reaxys:110052 Piperidine-2,6-dione piperidine-2,6-dione chebi_ontology 2,6-Diketopiperidine 2,6-piperidinedione Glutarimide CHEBI:5435 piperidine-2,6-dione CHEBI:5435 Beilstein:110052 Beilstein CAS:1121-89-7 ChemIDplus CAS:1121-89-7 KEGG COMPOUND CAS:1121-89-7 NIST Chemistry WebBook Gmelin:971891 Gmelin PMID:10783491 Europe PMC Reaxys:110052 Reaxys Piperidine-2,6-dione KEGG_COMPOUND piperidine-2,6-dione IUPAC 2,6-Diketopiperidine KEGG_COMPOUND 2,6-piperidinedione ChemIDplus Glutarimide KEGG_COMPOUND 0 C60H92N12O10 InChI=1S/C60H92N12O10/c1-35(2)31-43-53(75)67-45(33-39-19-11-9-12-20-39)59(81)71-29-17-25-47(71)55(77)70-50(38(7)8)58(80)64-42(24-16-28-62)52(74)66-44(32-36(3)4)54(76)68-46(34-40-21-13-10-14-22-40)60(82)72-30-18-26-48(72)56(78)69-49(37(5)6)57(79)63-41(23-15-27-61)51(73)65-43/h9-14,19-22,35-38,41-50H,15-18,23-34,61-62H2,1-8H3,(H,63,79)(H,64,80)(H,65,73)(H,66,74)(H,67,75)(H,68,76)(H,69,78)(H,70,77)/t41-,42-,43-,44-,45+,46+,47-,48-,49-,50-/m0/s1 IUAYMJGZBVDSGL-XNNAEKOYSA-N 1141.44736 1140.70594 [H][C@@]12CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@]1([H])CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC2=O)C(C)C)C(C)C CAS:113-73-5 KEGG:C11218 1,10-anhydro(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithine) Gramicidin S chebi_ontology Cyclo(L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl) Gramicidin C Gramicin S 1 Gramicin S-A gramicidin CHEBI:5530 gramicidin S CHEBI:5530 1,10-anhydro(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithine) IUPAC Gramicidin S KEGG_COMPOUND Cyclo(L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl) ChemIDplus Gramicidin C ChemIDplus Gramicin S 1 ChemIDplus Gramicin S-A ChEBI gramicidin ChEBI CAS:113-73-5 ChemIDplus CAS:113-73-5 KEGG COMPOUND A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis. 0 C58H73N7O17 InChI=1S/C58H73N7O17/c1-5-6-7-24-82-40-22-18-35(19-23-40)33-10-8-32(9-11-33)34-12-14-37(15-13-34)51(74)59-41-26-43(70)54(77)63-56(79)47-48(71)29(2)27-65(47)58(81)45(31(4)67)61-55(78)46(50(73)49(72)36-16-20-38(68)21-17-36)62-53(76)42-25-39(69)28-64(42)57(80)44(30(3)66)60-52(41)75/h8-23,29-31,39,41-50,54,66-73,77H,5-7,24-28H2,1-4H3,(H,59,74)(H,60,75)(H,61,78)(H,62,76)(H,63,79)/t29-,30+,31+,39+,41-,42-,43+,44-,45-,46-,47-,48-,49-,50-,54+/m0/s1 JHVAMHSQVVQIOT-MFAJLEFUSA-N 1140.23690 1139.50629 CCCCCOc1ccc(cc1)-c1ccc(cc1)-c1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)cc1)[C@@H](C)O Beilstein:7408417 CAS:166663-25-8 DrugBank:DB00362 KEGG:D03211 PMID:15482216 PMID:16770294 PMID:17316149 PMID:19072176 PMID:19113794 PMID:19877739 PMID:19877740 PMID:19877741 PMID:19877742 PMID:24165173 PMID:24955796 PMID:25473029 Reaxys:7408417 Wikipedia:Anidulafungin N-{(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-4''-(pentyloxy)-1,1':4',1''-terphenyl-4-carboxamide chebi_ontology Eraxis anidulafungin anidulafungina anidulafungine anidulafunginum CHEBI:55346 anidulafungin CHEBI:55346 Beilstein:7408417 Beilstein CAS:166663-25-8 ChemIDplus CAS:166663-25-8 DrugBank CAS:166663-25-8 KEGG DRUG PMID:15482216 Europe PMC PMID:16770294 Europe PMC PMID:17316149 Europe PMC PMID:19072176 Europe PMC PMID:19113794 Europe PMC PMID:19877739 Europe PMC PMID:19877740 Europe PMC PMID:19877741 Europe PMC PMID:19877742 Europe PMC PMID:24165173 Europe PMC PMID:24955796 Europe PMC PMID:25473029 Europe PMC Reaxys:7408417 Reaxys N-{(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-4''-(pentyloxy)-1,1':4',1''-terphenyl-4-carboxamide IUPAC Eraxis KEGG_DRUG anidulafungin ChemIDplus anidulafungina WHO_MedNet anidulafungine WHO_MedNet anidulafunginum WHO_MedNet An imidazolidine containing one or more oxo groups. chebi_ontology imidazolidinones CHEBI:55370 imidazolidinone CHEBI:55370 imidazolidinones ChEBI Oxazoles in which the N and O atoms are adjacent. CHEBI:46813 isoxazoles chebi_ontology 1,2-oxazoles CHEBI:55373 isoxazoles CHEBI:55373 isoxazoles ChEBI 1,2-oxazoles ChEBI An oxazolidine containing one or more oxo groups. chebi_ontology oxazolidinedione oxazolidinediones oxazolidinones CHEBI:55374 oxazolidinone CHEBI:55374 oxazolidinedione ChEBI oxazolidinediones ChEBI oxazolidinones ChEBI Any member of the cephamycin sub-group of cephem antibiotics, differing from cephalosporins in possessing a methoxy group at the 7alpha-position of the cephem nucleus, and in being resistant to beta-lactamase. 0 C8H7NO4SR2 213.212 213.00958 N12C([C@](*)(C1=O)OC)SCC(=C2C(O)=O)* PMID:1107228 chebi_ontology cephamycins CHEBI:55429 cephamycin CHEBI:55429 PMID:1107228 Europe PMC cephamycins ChEBI Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain. 0 C15H17O2R5 229.29430 229.12285 [H][C@]12O[C@]3([H])[C@H]([*])[C@@H]([*])[C@@](C)(C33CO3)C1(C[*])C([*])C([*])C(C)=C2 chebi_ontology trichothecenes CHEBI:55517 trichothecene CHEBI:55517 trichothecenes ChEBI A compound having the general formula RR'C(OH)OR'' (R'' =/= H). 0 CH2O2R2 46.025 46.00548 Hemiacetal hemiacetals chebi_ontology hemiacetals CHEBI:5653 hemiacetal CHEBI:5653 Hemiacetal KEGG_COMPOUND hemiacetals IUPAC hemiacetals ChEBI A cyclic compound having as ring members atoms of at least two different elements. Heterocyclic compound chebi_ontology compuesto heterociclico compuestos heterociclicos heterocycle heterocyclic compounds CHEBI:5686 heterocyclic compound CHEBI:5686 Heterocyclic compound KEGG_COMPOUND compuesto heterociclico IUPAC compuestos heterociclicos IUPAC heterocycle ChEBI heterocyclic compounds ChEBI Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-beta-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp. chebi_ontology echinocandins CHEBI:57248 echinocandin CHEBI:57248 echinocandins ChEBI A D-alpha-amino acid zwitterion that is D-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. 0 C5H9NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 ONIBWKKTOPOVIA-SCSAIBSYSA-N 115.13050 115.06333 [O-]C(=O)[C@H]1CCC[NH2+]1 MetaCyc:D-PROLINE (2R)-pyrrolidinium-2-carboxylate chebi_ontology D-proline CHEBI:57726 D-proline zwitterion CHEBI:57726 (2R)-pyrrolidinium-2-carboxylate IUPAC D-proline UniProt Zwitterionic form of 6-aminopenicillanic acid arising from migration of a proton from the carboxy group to the 6-amino group; major species at pH 7.3. 0 C8H12N2O3S InChI=1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1 NGHVIOIJCVXTGV-ALEPSDHESA-N 216.25700 216.05686 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2[NH3+])C([O-])=O 6-azaniumyl-2,2-dimethylpenam-3alpha-carboxylate chebi_ontology (2S,5R,6R)-6-azaniumyl-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 6-aminopenicillanate CHEBI:57869 6-aminopenicillanic acid zwitterion CHEBI:57869 6-azaniumyl-2,2-dimethylpenam-3alpha-carboxylate IUPAC (2S,5R,6R)-6-azaniumyl-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate ChEBI 6-aminopenicillanate UniProt An ammonium ion that is the trication of hygromycin B arising from protonation of the three amino groups; major species at pH 7.3. +3 C20H40N3O13 InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/p+3/t5-,6?,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20-/m1/s1 GRRNUXAQVGOGFE-NZSRVPFOSA-Q 530.54390 530.25447 C[NH2+][C@H]1C[C@@H]([NH3+])[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@@H]3O[C@@]4(O[C@H](C([NH3+])CO)[C@H](O)[C@H](O)[C@H]4O)O[C@H]23)[C@@H]1O (1R,2S,3R,5S,6R)-3-azaniumyl-2,6-dihydroxy-5-(methylazaniumyl)cyclohexyl O-6-azaniumyl-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-beta-D-talopyranoside chebi_ontology hygromycin B hygromycin B trication CHEBI:57971 hygromycin B(3+) CHEBI:57971 (1R,2S,3R,5S,6R)-3-azaniumyl-2,6-dihydroxy-5-(methylazaniumyl)cyclohexyl O-6-azaniumyl-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-beta-D-talopyranoside IUPAC hygromycin B UniProt hygromycin B trication ChEBI Trication of streptomycin arising from protonation of the guanidino and secondary amino groups. +3 C21H42N7O12 InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/p+3/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1 UCSJYZPVAKXKNQ-HZYVHMACSA-Q 584.59790 584.28750 C[NH2+][C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@@H](O[C@@H](C)[C@]1(O)C=O)O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=[NH2+])[C@@H](O)[C@@H]1NC(N)=[NH2+] (1R,2R,3S,4R,5R,6S)-2,4-bis{[amino(iminio)methyl]amino}-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-[2-deoxy-2-(methylammonio)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranoside chebi_ontology streptomycin streptomycin trication CHEBI:58007 streptomycin(3+) CHEBI:58007 (1R,2R,3S,4R,5R,6S)-2,4-bis{[amino(iminio)methyl]amino}-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-[2-deoxy-2-(methylammonio)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranoside IUPAC streptomycin UniProt streptomycin trication ChEBI An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3. -1 C10H11N5O6P InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1 IVOMOUWHDPKRLL-KQYNXXCUSA-M 328.19800 328.04524 Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O PMID:7870041 PMID:7870042 Reaxys:3720459 adenosine 3',5'-phosphate chebi_ontology 3',5'-cyclic AMP 3',5'-cyclic AMP anion adenosine 3',5'-cyclic monophosphate adenosine 3',5'-cyclic monophosphate anion adenosine 3',5'-cyclic monophosphate(1-) CHEBI:58165 3',5'-cyclic AMP(1-) CHEBI:58165 PMID:7870041 Europe PMC PMID:7870042 Europe PMC Reaxys:3720459 Reaxys adenosine 3',5'-phosphate IUPAC 3',5'-cyclic AMP UniProt 3',5'-cyclic AMP anion ChEBI adenosine 3',5'-cyclic monophosphate ChEBI adenosine 3',5'-cyclic monophosphate anion ChEBI adenosine 3',5'-cyclic monophosphate(1-) ChEBI An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. 0 C21H39NO6 InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1 ZZIKIHCNFWXKDY-GNTQXERDSA-N 401.544 401.27774 CCCCCCC(=O)CCCCCC\C=C\C[C@@H](O)[C@H](O)[C@@](N)(CO)C(O)=O AGR:IND607305181 Beilstein:5113331 CAS:35891-70-4 KEGG:C19914 KNApSAcK:C00016936 LIPID_MAPS_instance:LMFA01060203 PDBeChem:VRP PMID:15679316 PMID:21456524 PMID:23178537 PMID:23659342 PMID:23802886 PMID:23957439 PMID:24141140 PMID:24395529 PMID:24456332 PMID:27621809 PMID:28621883 PMID:30123648 PMID:30883241 PMID:31447688 PMID:31639005 PMID:31701696 PMID:32091078 PMID:32212314 PMID:32435178 PMID:32954686 PMID:33378044 PMID:33441497 PMID:33482299 PMID:33558761 PMID:33731109 PMID:34324668 PMID:4694226 PMID:5076310 PMID:8020136 Reaxys:5113331 Wikipedia:Myriocin (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid chebi_ontology (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid ISP-1 ISP-I antibiotic ISP-1 antibiotic ISP-I thermozymocidin CHEBI:582124 myriocin CHEBI:582124 AGR:IND607305181 Europe PMC Beilstein:5113331 Beilstein CAS:35891-70-4 ChemIDplus LIPID_MAPS_instance:LMFA01060203 LIPID MAPS PMID:15679316 ChEMBL PMID:21456524 Europe PMC PMID:23178537 Europe PMC PMID:23659342 Europe PMC PMID:23802886 Europe PMC PMID:23957439 Europe PMC PMID:24141140 Europe PMC PMID:24395529 Europe PMC PMID:24456332 Europe PMC PMID:27621809 Europe PMC PMID:28621883 Europe PMC PMID:30123648 Europe PMC PMID:30883241 Europe PMC PMID:31447688 Europe PMC PMID:31639005 Europe PMC PMID:31701696 Europe PMC PMID:32091078 Europe PMC PMID:32212314 Europe PMC PMID:32435178 Europe PMC PMID:32954686 Europe PMC PMID:33378044 Europe PMC PMID:33441497 Europe PMC PMID:33482299 Europe PMC PMID:33558761 Europe PMC PMID:33731109 Europe PMC PMID:34324668 Europe PMC PMID:4694226 Europe PMC PMID:5076310 Europe PMC PMID:8020136 Europe PMC Reaxys:5113331 Reaxys (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid IUPAC (2S,3R,4R)-(E)-2-amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic acid ChEBI (2S,3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid ChEBI ISP-1 KEGG_COMPOUND ISP-I ChEBI antibiotic ISP-1 ChEBI antibiotic ISP-I ChEBI thermozymocidin ChemIDplus A quadruply-charged organic cation arising from protonation of the four amino groups of kanamycin A; major species at pH 7.3. +4 C18H40N4O11 InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/p+4/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1 SBUJHOSQTJFQJX-NOAMYHISSA-R 488.53040 488.26716 [NH3+]C[C@H]1O[C@H](O[C@@H]2[C@@H]([NH3+])C[C@@H]([NH3+])[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H]([NH3+])[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O (1S,2R,3R,4S,6R)-4,6-diazaniumyl-3-(6-azaniumyl-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside chebi_ontology kanamycin A kanamycin A tetracation CHEBI:58214 kanamycin A(4+) CHEBI:58214 (1S,2R,3R,4S,6R)-4,6-diazaniumyl-3-(6-azaniumyl-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside IUPAC kanamycin A UniProt kanamycin A tetracation ChEBI A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals. 0 C4H5NO2 InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6) KGVPNLBXJKTABS-UHFFFAOYSA-N 99.08800 99.03203 Cc1cc(O)no1 CAS:10004-44-1 KEGG:C11103 PMID:21959994 PMID:22307860 PPDB:388 Pesticides:hymexazol Reaxys:606046 5-methyl-1,2-oxazol-3(2H)-one chebi_ontology 3-Hydroxy-5-methylisoxazole 5-Methyl-3(2H)-isoxazolone 5-Methyl-3-hydroxyisoxazole 5-Methylisoxazol-3-ol F 319 F-319 Hydroxyisoxazole Hymexazole NSC 217971 SF-6505 CHEBI:5827 hymexazol CHEBI:5827 CAS:10004-44-1 ChemIDplus CAS:10004-44-1 KEGG COMPOUND PMID:21959994 Europe PMC PMID:22307860 Europe PMC Pesticides:hymexazol Alan Wood's Pesticides Reaxys:606046 Reaxys 5-methyl-1,2-oxazol-3(2H)-one IUPAC 3-Hydroxy-5-methylisoxazole ChemIDplus 5-Methyl-3(2H)-isoxazolone ChemIDplus 5-Methyl-3-hydroxyisoxazole ChemIDplus 5-Methylisoxazol-3-ol ChemIDplus F 319 ChemIDplus F-319 ChemIDplus Hydroxyisoxazole ChemIDplus Hymexazole ChemIDplus NSC 217971 ChemIDplus SF-6505 ChemIDplus The conjugate base of a nucleoside 3',5'-cyclic phosphate. -1 C5H6O5PR2 177.07190 176.99528 [O-]P1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1 chebi_ontology a nucleoside 3',5'-cyclic phosphate nucleoside 3',5'-cyclic phosphate anions CHEBI:58464 nucleoside 3',5'-cyclic phosphate anion CHEBI:58464 a nucleoside 3',5'-cyclic phosphate UniProt nucleoside 3',5'-cyclic phosphate anions ChEBI An organic cation that is the pentacation of kanamycin B, obtained by protonation of the primary amino groups. +5 C18H42N5O10 InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/p+5/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1 SKKLOUVUUNMCJE-FQSMHNGLSA-S 488.55360 488.29042 [NH3+]C[C@H]1O[C@H](O[C@@H]2[C@@H]([NH3+])C[C@@H]([NH3+])[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H]([NH3+])[C@H]3O)[C@H]2O)[C@H]([NH3+])[C@@H](O)[C@@H]1O (1R,2S,3S,4R,6S)-4,6-diammmonio-3-(3-ammonio-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranoside chebi_ontology kanamycin B CHEBI:58549 kanamycin B(5+) CHEBI:58549 (1R,2S,3S,4R,6S)-4,6-diammmonio-3-(3-ammonio-3-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranoside IUPAC kanamycin B UniProt An amino-acid residue protonated on nitrogen. chebi_ontology amino acid cation residue amino acid cation residues amino-acid cation residue amino-acid cation residues cationic amino acid residue cationic amino acid residues cationic amino-acid residues CHEBI:58942 cationic amino-acid residue CHEBI:58942 amino acid cation residue ChEBI amino acid cation residues ChEBI amino-acid cation residue ChEBI amino-acid cation residues ChEBI cationic amino acid residue ChEBI cationic amino acid residues ChEBI cationic amino-acid residues ChEBI An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated. chebi_ontology organophosphate oxoanions CHEBI:58945 organophosphate oxoanion CHEBI:58945 organophosphate oxoanions ChEBI Any fatty acid anion with a chain length greater than C22. -1 CO2R 44.010 43.98983 [O-]C([*])=O chebi_ontology a very long-chain fatty acid very long-chain fatty acid anions CHEBI:58950 very long-chain fatty acid anion CHEBI:58950 a very long-chain fatty acid UniProt very long-chain fatty acid anions ChEBI Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6). -1 CO2R 44.010 43.98983 [O-]C([*])=O chebi_ontology a short-chain fatty acid short-chain fatty acid anions CHEBI:58951 short-chain fatty acid anion CHEBI:58951 a short-chain fatty acid UniProt short-chain fatty acid anions ChEBI Any fatty acid anion in which there is no C-C unsaturation. chebi_ontology saturated fatty acid anions CHEBI:58953 saturated fatty acid anion CHEBI:58953 saturated fatty acid anions ChEBI Any saturated fatty acid anion lacking a carbon side-chain. chebi_ontology straight-chain saturated fatty acid anions CHEBI:58954 straight-chain saturated fatty acid anion CHEBI:58954 straight-chain saturated fatty acid anions ChEBI Any fatty acid anion with a carbon side-chain or isopropyl termination. chebi_ontology branched-chain fatty acid anions CHEBI:58955 branched-chain fatty acid anion CHEBI:58955 branched-chain fatty acid anions ChEBI An organic anion of general formula RS(=O)2O(-) where R is an organyl group. -1 O4SR 96.06300 95.95173 [O-]S(=O)(=O)O[*] chebi_ontology organosulfate oxoanions CHEBI:58958 organosulfate oxoanion CHEBI:58958 organosulfate oxoanions ChEBI Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria. chebi_ontology polymixin polymycin polymyxins CHEBI:59062 polymyxin CHEBI:59062 polymixin ChEBI polymycin ChEBI polymyxins ChEBI A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus. 0 C53H100N16O13 InChI=1S/C53H100N16O13/c1-9-30(6)12-10-11-13-41(72)60-33(14-20-54)48(77)69-43(32(8)71)53(82)65-36(17-23-57)45(74)64-38-19-25-59-52(81)42(31(7)70)68-49(78)37(18-24-58)62-44(73)34(15-21-55)63-50(79)39(26-28(2)3)67-51(80)40(27-29(4)5)66-46(75)35(16-22-56)61-47(38)76/h28-40,42-43,70-71H,9-27,54-58H2,1-8H3,(H,59,81)(H,60,72)(H,61,76)(H,62,73)(H,63,79)(H,64,74)(H,65,82)(H,66,75)(H,67,80)(H,68,78)(H,69,77)/t30-,31-,32-,33+,34+,35+,36+,37+,38+,39+,40-,42+,43+/m1/s1 XDJYMJULXQKGMM-RVYUQJQSSA-N 1169.46050 1168.76558 CC[C@@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O Beilstein:8609559 CAS:7722-44-3 PMID:13058849 PMID:1650428 PMID:16931410 PMID:18625681 PMID:25249467 PMID:25609230 PMID:25832483 Reaxys:8609559 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine} Colistin A chebi_ontology Colistin IV Polymixin E1 Polymyxin E1 CHEBI:59064 colistin A CHEBI:59064 Beilstein:8609559 Beilstein CAS:7722-44-3 ChemIDplus PMID:13058849 Europe PMC PMID:1650428 Europe PMC PMID:16931410 Europe PMC PMID:18625681 Europe PMC PMID:25249467 Europe PMC PMID:25609230 Europe PMC PMID:25832483 Europe PMC Reaxys:8609559 Reaxys 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine} IUPAC Colistin A ChemIDplus Colistin IV ChemIDplus Polymixin E1 ChemIDplus Polymyxin E1 ChemIDplus Conjugate base of oxolinic acid. -1 C13H10NO5 InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)/p-1 KYGZCKSPAKDVKC-UHFFFAOYSA-M 260.22220 260.05645 CCn1cc(C([O-])=O)c(=O)c2cc3OCOc3cc12 Beilstein:3563086 PMID:776048 5-ethyl-8-oxo-5,8-dihydro-2H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylate chebi_ontology 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylate CHEBI:59066 oxolinate CHEBI:59066 Beilstein:3563086 Beilstein PMID:776048 Europe PMC 5-ethyl-8-oxo-5,8-dihydro-2H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylate IUPAC 5-ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylate IUPAC Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*). CHEBI:76786 chebi_ontology EC 3.4.24.* (metalloendopeptidase) inhibitors EC 3.4.24.* inhibitor EC 3.4.24.* inhibitors inhibitor of metalloendopeptidases inhibitor of metalloendopeptidases (EC 3.4.24.*) inhibitors of metalloendopeptidases inhibitors of metalloendopeptidases (EC 3.4.24.*) metalloendopeptidase (EC 3.4.24.*) inhibitor metalloendopeptidase (EC 3.4.24.*) inhibitors metalloendopeptidase inhibitors CHEBI:59107 EC 3.4.24.* (metalloendopeptidase) inhibitor CHEBI:59107 EC 3.4.24.* (metalloendopeptidase) inhibitors ChEBI EC 3.4.24.* inhibitor ChEBI EC 3.4.24.* inhibitors ChEBI inhibitor of metalloendopeptidases ChEBI inhibitor of metalloendopeptidases (EC 3.4.24.*) ChEBI inhibitors of metalloendopeptidases ChEBI inhibitors of metalloendopeptidases (EC 3.4.24.*) ChEBI metalloendopeptidase (EC 3.4.24.*) inhibitor ChEBI metalloendopeptidase (EC 3.4.24.*) inhibitors ChEBI metalloendopeptidase inhibitors ChEBI A substance used as an indicator of a biological state. chebi_ontology biological marker CHEBI:59163 biomarker CHEBI:59163 biological marker ChEBI Any fatty acid whose skeletal carbon atoms form an unbranched open chain. chebi_ontology straight-chain fatty acids CHEBI:59202 straight-chain fatty acid CHEBI:59202 straight-chain fatty acids ChEBI A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid. chebi_ontology straight-chain FA anion straight-chain FA anions straight-chain fatty acid anions CHEBI:59203 straight-chain fatty acid anion CHEBI:59203 straight-chain FA anion ChEBI straight-chain FA anions ChEBI straight-chain fatty acid anions ChEBI An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132). chebi_ontology EC 1.14.13.132 (squalene monooxygenase) inhibitors squalene 2,3-oxidocyclase inhibitor squalene 2,3-oxidocyclase inhibitors squalene epoxidase inhibitor squalene epoxidase inhibitors squalene hydroxylase inhibitor squalene hydroxylase inhibitors squalene monooxygenase (EC 1.14.13.132) inhibitor squalene monooxygenase (EC 1.14.13.132) inhibitors squalene monooxygenase inhibitor squalene monooxygenase inhibitors squalene oxydocyclase inhibitor squalene oxydocyclase inhibitors squalene-2,3-epoxidase inhibitor squalene-2,3-epoxidase inhibitors squalene-2,3-epoxide cyclase inhibitor squalene-2,3-epoxide cyclase inhibitors CHEBI:59285 EC 1.14.13.132 (squalene monooxygenase) inhibitor CHEBI:59285 EC 1.14.13.132 (squalene monooxygenase) inhibitors ChEBI squalene 2,3-oxidocyclase inhibitor ChEBI squalene 2,3-oxidocyclase inhibitors ChEBI squalene epoxidase inhibitor ChEBI squalene epoxidase inhibitors ChEBI squalene hydroxylase inhibitor ChEBI squalene hydroxylase inhibitors ChEBI squalene monooxygenase (EC 1.14.13.132) inhibitor ChEBI squalene monooxygenase (EC 1.14.13.132) inhibitors ChEBI squalene monooxygenase inhibitor ChEBI squalene monooxygenase inhibitors ChEBI squalene oxydocyclase inhibitor ChEBI squalene oxydocyclase inhibitors ChEBI squalene-2,3-epoxidase inhibitor ChEBI squalene-2,3-epoxidase inhibitors ChEBI squalene-2,3-epoxide cyclase inhibitor ChEBI squalene-2,3-epoxide cyclase inhibitors ChEBI The conjugate acid of cefepime. +1 C19H25N6O5S2 InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/p+1/b23-12-/t13-,17-/m1/s1 HVFLCNVBZFFHBT-ZKDACBOMSA-O 481.56900 481.13224 [H][C@]12SCC(C[N+]3(C)CCCC3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O Beilstein:5196242 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidinium 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylic acid chebi_ontology cefepime conjugate acid CHEBI:59349 cefepime(1+) CHEBI:59349 Beilstein:5196242 Beilstein 1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidinium IUPAC 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylic acid IUPAC cefepime conjugate acid ChEBI The dianion formed by removal of a proton from each of the carboxylic acid groups of cefotetan. -2 C17H15N7O8S4 InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/p-2/b12-6-/t13?,15-,17+/m1/s1 SRZNHPXWXCNNDU-IXOPCIAXSA-L 573.60300 572.98759 [H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)C1SC(S1)=C(C(N)=O)C([O-])=O)OC)C([O-])=O Beilstein:5701969 (6R,7S)-7-({[4-(2-amino-1-carboxylato-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7beta-({[4-(2-amino-1-carboxylato-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylate chebi_ontology cefotetan dianion CHEBI:59358 cefotetan(2-) CHEBI:59358 Beilstein:5701969 Beilstein (6R,7S)-7-({[4-(2-amino-1-carboxylato-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC 7beta-({[4-(2-amino-1-carboxylato-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylate IUPAC cefotetan dianion ChEBI The anion resulting from the removal of a proton from the carboxylic acid group of cephalexin. -1 C16H16N3O4S InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/p-1/t10-,11-,15-/m1/s1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-M 346.38100 346.08670 [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C([O-])=O Beilstein:8358366 (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylate chebi_ontology cefalexin anion cefalexin(1-) cephalexin anion CHEBI:59392 cephalexin(1-) CHEBI:59392 Beilstein:8358366 Beilstein (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylate IUPAC cefalexin anion ChEBI cefalexin(1-) ChEBI cephalexin anion ChEBI Any substance that inhibits the synthesis of DNA. chebi_ontology DNA synthesis inhibitors CHEBI:59517 DNA synthesis inhibitor CHEBI:59517 DNA synthesis inhibitors ChEBI An organic phosphonic acid derivative in which one or more oxygen atoms of the phosphonate group(s) has been deprotonated. chebi_ontology organophosphonate oxoanions CHEBI:59635 organophosphonate oxoanion CHEBI:59635 organophosphonate oxoanions ChEBI Any fatty acid containing at least one aldehydic or ketonic group in addition to the carboxylic acid group. PMID:6434570 PMID:8454196 PMID:8638935 chebi_ontology oxo fatty acids CHEBI:59644 oxo fatty acid CHEBI:59644 PMID:6434570 Europe PMC PMID:8454196 Europe PMC PMID:8638935 Europe PMC oxo fatty acids ChEBI An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50). Wikipedia:Serine_C-palmitoyltransferase chebi_ontology 3-oxosphinganine synthetase inhibitor 3-oxosphinganine synthetase inhibitors EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors EC 2.3.1.50 inhibitor EC 2.3.1.50 inhibitors SPT inhibitor SPT inhibitors acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors serine C-palmitoyltransferase inhibitor serine C-palmitoyltransferase inhibitors serine palmitoyltransferase inhibitor serine palmitoyltransferase inhibitors CHEBI:59647 EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor CHEBI:59647 3-oxosphinganine synthetase inhibitor ChEBI 3-oxosphinganine synthetase inhibitors ChEBI EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors ChEBI EC 2.3.1.50 inhibitor ChEBI EC 2.3.1.50 inhibitors ChEBI SPT inhibitor ChEBI SPT inhibitors ChEBI acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor ChEBI acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors ChEBI palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor ChEBI palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors ChEBI serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor ChEBI serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors ChEBI serine C-palmitoyltransferase inhibitor ChEBI serine C-palmitoyltransferase inhibitors ChEBI serine palmitoyltransferase inhibitor ChEBI serine palmitoyltransferase inhibitors ChEBI A fatty acid containing at least one amino substituent. chebi_ontology amino FA amino fatty acids carboxylated base carboxylated bases lipoamino acid lipoamino acids CHEBI:59650 amino fatty acid CHEBI:59650 amino FA ChEBI amino fatty acids ChEBI carboxylated base ChEBI carboxylated bases ChEBI lipoamino acid ChEBI lipoamino acids ChEBI A class of nucleoside-peptide antibiotics which inhibit fungal chitin biosynthesis by inhibiting chitin synthase. Generally consist of a heterocyclic moiety (usually a nucleobase), an amino hexuronic acid and an amino acid containing a pyridine ring. chebi_ontology nikkomycins CHEBI:59668 nikkomycin CHEBI:59668 nikkomycins ChEBI A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16). Wikipedia:Chitin_synthase chebi_ontology EC 2.4.1.16 (chitin synthase) inhibitors EC 2.4.1.16 inhibitor EC 2.4.1.16 inhibitors UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors chitin synthase (EC 2.4.1.16) inhibitor chitin synthase (EC 2.4.1.16) inhibitors chitin synthase inhibitor chitin synthase inhibitors chitin synthesis inhibitor chitin synthesis inhibitors chitin synthetase inhibitor chitin synthetase inhibitors chitin-UDP N-acetylglucosaminyltransferase inhibitor chitin-UDP N-acetylglucosaminyltransferase inhibitors chitin-UDP acetyl-glucosaminyl transferase inhibitor chitin-UDP acetyl-glucosaminyl transferase inhibitors chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors trans-N-acetylglucosaminosylase inhibitor trans-N-acetylglucosaminosylase inhibitors CHEBI:59672 EC 2.4.1.16 (chitin synthase) inhibitor CHEBI:59672 EC 2.4.1.16 (chitin synthase) inhibitors ChEBI EC 2.4.1.16 inhibitor ChEBI EC 2.4.1.16 inhibitors ChEBI UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor ChEBI UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors ChEBI chitin synthase (EC 2.4.1.16) inhibitor ChEBI chitin synthase (EC 2.4.1.16) inhibitors ChEBI chitin synthase inhibitor ChEBI chitin synthase inhibitors ChEBI chitin synthesis inhibitor ChEBI chitin synthesis inhibitors ChEBI chitin synthetase inhibitor ChEBI chitin synthetase inhibitors ChEBI chitin-UDP N-acetylglucosaminyltransferase inhibitor ChEBI chitin-UDP N-acetylglucosaminyltransferase inhibitors ChEBI chitin-UDP acetyl-glucosaminyl transferase inhibitor ChEBI chitin-UDP acetyl-glucosaminyl transferase inhibitors ChEBI chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor ChEBI chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors ChEBI trans-N-acetylglucosaminosylase inhibitor ChEBI trans-N-acetylglucosaminosylase inhibitors ChEBI A polymyxin having a 6-methylheptanoyl group at the amino terminus. 0 C52H98N16O13 InChI=1S/C52H98N16O13/c1-27(2)11-9-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-28(3)4)66-50(79)39(26-29(5)6)65-45(74)34(15-21-55)60-46(37)75/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76)/t30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+/m1/s1 KNIWPHSUTGNZST-SSWRVQTPSA-N 1155.43390 1154.74993 CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O Beilstein:8185577 CAS:7239-48-7 PMID:16931410 PMID:18625681 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine] chebi_ontology polymyxin E2 CHEBI:59673 colistin B CHEBI:59673 Beilstein:8185577 Beilstein CAS:7239-48-7 ChemIDplus PMID:16931410 Europe PMC PMID:18625681 Europe PMC 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine] IUPAC polymyxin E2 ChEBI A class of polyene antifungal antibiotics produced by Streptomyces noursei, and other Streptomyces species. PMID:12230565 PMID:15504830 PMID:1793301 Patent:US2832719 Patent:US3517100 chebi_ontology CHEBI:59676 nystatins CHEBI:59676 PMID:12230565 Europe PMC PMID:15504830 Europe PMC PMID:1793301 Europe PMC Compounds containing one or more phosphoric acid units. chebi_ontology CHEBI:59698 phosphoric acids CHEBI:59698 A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. chebi_ontology nucleophile nucleophiles nucleophilic reagents CHEBI:59740 nucleophilic reagent CHEBI:59740 nucleophile ChEBI nucleophiles ChEBI nucleophilic reagents ChEBI A fatty acid with an amino substituent at position C-2. PMID:3279209 chebi_ontology a-amino fatty acid a-amino fatty acids alpha-amino FA alpha-amino fatty acids CHEBI:59755 alpha-amino fatty acid CHEBI:59755 PMID:3279209 Europe PMC a-amino fatty acid ChEBI a-amino fatty acids ChEBI alpha-amino FA ChEBI alpha-amino fatty acids ChEBI An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ. chebi_ontology acetals CHEBI:59769 acetal CHEBI:59769 acetals ChEBI An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring. chebi_ontology cyclic acetals CHEBI:59770 cyclic acetal CHEBI:59770 cyclic acetals ChEBI A hemiacetal having the structure RR(1)C(OH)OR(2) (R, R(1), R(2) =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group. 0 CHO2R3 45.017 44.99765 C(*)(O)(O*)* chebi_ontology hemiketals CHEBI:59772 hemiketal CHEBI:59772 hemiketals ChEBI An acetal of formula R2C(OR)2 (R =/= H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals. chebi_ontology ketals CHEBI:59777 ketal CHEBI:59777 ketals ChEBI A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring. chebi_ontology cyclic ketals CHEBI:59779 cyclic ketal CHEBI:59779 cyclic ketals ChEBI A hemiacetal having the structure R2C(OH)OR (R =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals. chebi_ontology cyclic hemiketals CHEBI:59780 cyclic hemiketal CHEBI:59780 cyclic hemiketals ChEBI The sulfur analogue of 'acetal'. The term includes monothioacetals having the structure R2C(OR')(SR') (subclass monothioketals, R =/= H); and dithioacetals having the structure R2C(SR')2 (subclass dithioketals, R =/= H, R' =/= H). chebi_ontology thioacetals CHEBI:59792 thioacetal CHEBI:59792 thioacetals ChEBI A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R =/= H, as a subclass. 0 COSR4 60.07500 59.96699 [*]OC([*])([*])S[*] chebi_ontology monothioacetals thioacetal CHEBI:59793 monothioacetal CHEBI:59793 monothioacetals ChEBI thioacetal ChEBI Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group. -1 C2H3NO2R 73.051 73.01638 [C@H](C(=O)[O-])(N)* chebi_ontology L-alpha-amino carboxylate CHEBI:59814 L-alpha-amino acid anion CHEBI:59814 L-alpha-amino carboxylate ChEBI An acetylenic and an olefinic compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond. chebi_ontology enynes CHEBI:59831 enyne CHEBI:59831 enynes ChEBI The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety. chebi_ontology OH-FA anion OH-FA-anions OH-fatty acid anion OH-fatty acid anions hydroxy fatty acid anions CHEBI:59835 hydroxy fatty acid anion CHEBI:59835 OH-FA anion ChEBI OH-FA-anions ChEBI OH-fatty acid anion ChEBI OH-fatty acid anions ChEBI hydroxy fatty acid anions ChEBI A fatty acid anion carrying one or more oxo substituents chebi_ontology oxo fatty acid anions oxo-FA anion oxo-FA anions CHEBI:59836 oxo fatty acid anion CHEBI:59836 oxo fatty acid anions ChEBI oxo-FA anion ChEBI oxo-FA anions ChEBI Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes. chebi_ontology depigmentation agent depigmentation agents depigmentation drugs depigmentor depigmentors CHEBI:59864 depigmentation drug CHEBI:59864 depigmentation agent ChEBI depigmentation agents ChEBI depigmentation drugs ChEBI depigmentor ChEBI depigmentors ChEBI Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group. 0 C2H4NO2R 74.059 74.02420 [NH3+][C@@H]([*])C([O-])=O chebi_ontology L-alpha-amino acid zwitterions an L-alpha-amino acid CHEBI:59869 L-alpha-amino acid zwitterion CHEBI:59869 L-alpha-amino acid zwitterions ChEBI an L-alpha-amino acid UniProt Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group. 0 C2H4NO2R 74.059 74.02420 [NH3+][C@H]([*])C([O-])=O chebi_ontology D-alpha-amino acid zwitterions a D-alpha-amino acid CHEBI:59871 D-alpha-amino acid zwitterion CHEBI:59871 D-alpha-amino acid zwitterions ChEBI a D-alpha-amino acid UniProt A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. chebi_ontology Chemische Substanz CHEBI:59999 chemical substance CHEBI:59999 Chemische Substanz ChEBI A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. chebi_ontology Mischung CHEBI:60004 mixture CHEBI:60004 Mischung ChEBI A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue. 0 C72H101N17O26 InChI=1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43+,44+,45+,46+,47+,48+,49+,50-,60+,61+/m1/s1 DOAKLVKFURWEDJ-RWDRXURGSA-N 1620.67060 1619.71037 CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1[C@@H](C)OC(=O)[C@H](CC(=O)c2ccccc2N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)CNC1=O)[C@H](C)CC(O)=O CHEBI:29570 CHEBI:321017 CHEBI:478132 CHEBI:478255 CAS:103060-53-3 DrugBank:DB00080 KEGG:C12013 KEGG:D01080 PMID:14622998 PMID:15227539 PMID:15271343 PMID:15500379 PMID:15815985 PMID:15870461 PMID:16311632 PMID:17402833 PMID:18360590 PMID:18989686 PMID:19015332 PMID:19303806 PMID:19875242 PMID:20522545 Wikipedia:Daptomycin Daptomycin N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-alpha-asparagine daptomycin chebi_ontology Cidecin Cubicin LY 146032 N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon(1)-lactone daptomicina daptomycin daptomycine daptomycinum CHEBI:600103 daptomycin CHEBI:600103 CAS:103060-53-3 ChemIDplus CAS:103060-53-3 KEGG COMPOUND PMID:14622998 ChEMBL PMID:15227539 Europe PMC PMID:15271343 Europe PMC PMID:15500379 Europe PMC PMID:15815985 Europe PMC PMID:15870461 Europe PMC PMID:16311632 Europe PMC PMID:17402833 Europe PMC PMID:18360590 Europe PMC PMID:18989686 Europe PMC PMID:19015332 Europe PMC PMID:19303806 Europe PMC PMID:19875242 Europe PMC PMID:20522545 Europe PMC Daptomycin KEGG_COMPOUND N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]-L-alpha-asparagine IUPAC daptomycin ChEMBL Cidecin ChemIDplus Cubicin ChemIDplus LY 146032 ChemIDplus N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone ChEBI N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon(1)-lactone ChemIDplus daptomicina ChemIDplus daptomycin ChemIDplus daptomycine ChemIDplus daptomycinum ChemIDplus A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.. Wikipedia:Polymer Polymer chebi_ontology Kunststoff CHEBI:60027 polymer CHEBI:60027 Polymer ChEBI Kunststoff ChEBI The zwitterion formed from L-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH. 0 C5H9NO2 InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 115.13050 115.06333 [O-]C(=O)[C@@H]1CCC[NH2+]1 CHEBI:58054 MetaCyc:PRO (2S)-pyrrolidinium-2-carboxylate chebi_ontology L-proline CHEBI:60039 L-proline zwitterion CHEBI:60039 (2S)-pyrrolidinium-2-carboxylate IUPAC L-proline UniProt A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy. 0 C56H71N9O23S InChI=1S/C56H71N9O23S/c1-4-5-6-17-86-32-14-11-28(12-15-32)39-21-33(63-87-39)27-7-9-29(10-8-27)49(75)58-34-20-38(70)52(78)62-54(80)45-46(72)25(2)23-65(45)56(82)43(37(69)22-41(57)71)60-53(79)44(48(74)47(73)30-13-16-36(68)40(18-30)88-89(83,84)85)61-51(77)35-19-31(67)24-64(35)55(81)42(26(3)66)59-50(34)76/h7-16,18,21,25-26,31,34-35,37-38,42-48,52,66-70,72-74,78H,4-6,17,19-20,22-24H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)(H,83,84,85)/t25-,26+,31+,34-,35-,37+,38+,42-,43-,44-,45-,46-,47-,48-,52+/m0/s1 PIEUQSKUWLMALL-YABMTYFHSA-N 1270.27400 1269.43835 CCCCCOc1ccc(cc1)-c1cc(no1)-c1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)c(OS(O)(=O)=O)c1)[C@H](O)CC(N)=O CHEBI:473847 CHEBI:530001 CHEBI:533643 CHEBI:533785 Beilstein:9610508 CAS:235114-32-6 DrugBank:DB01141 KEGG:D08218 PMID:17194830 PMID:17307974 PMID:17325217 PMID:17325225 PMID:17420211 PMID:17785512 5-[(1S,2S)-2-{(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-[(4-{5-[4-(pentyloxy)phenyl]isoxazol-3-yl}benzoyl)amino]tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl}-1,2-dihydroxyethyl]-2-hydroxyphenyl hydrogen sulfate 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-(4-{5-[4-(pentyloxy)phenyl]isoxazol-3-yl}benzoyl)-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-(3S,4S)-3-hydroxy-4-methyl-L-proline} chebi_ontology Mycamine micafungin CHEBI:600520 micafungin CHEBI:600520 Beilstein:9610508 Beilstein CAS:235114-32-6 ChemIDplus CAS:235114-32-6 KEGG DRUG PMID:17194830 ChEMBL PMID:17307974 ChEMBL PMID:17325217 ChEMBL PMID:17325225 ChEMBL PMID:17420211 ChEMBL PMID:17785512 ChEMBL 5-[(1S,2S)-2-{(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-[(4-{5-[4-(pentyloxy)phenyl]isoxazol-3-yl}benzoyl)amino]tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl}-1,2-dihydroxyethyl]-2-hydroxyphenyl hydrogen sulfate IUPAC 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-(4-{5-[4-(pentyloxy)phenyl]isoxazol-3-yl}benzoyl)-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-(3S,4S)-3-hydroxy-4-methyl-L-proline} IUPAC Mycamine ChemIDplus micafungin ChemIDplus micafungin KEGG_DRUG The mono-anion resulting from the removal of a proton from one of the carboxyic acid groups of ertapenem. -1 C22H24N3O7S InChI=1S/C22H25N3O7S/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32)/p-1/t9-,10-,13+,14+,15-,16-/m1/s1 JUZNIMUFDBIJCM-ANEDZVCMSA-M 474.50700 474.13404 [H][C@]1(C[NH2+][C@@]([H])(C1)C(=O)Nc1cccc(c1)C([O-])=O)SC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])[C@H]1C)C([O-])=O Beilstein:8177331 chebi_ontology CHEBI:60071 ertapenem(1-) CHEBI:60071 Beilstein:8177331 Beilstein A metal cation with a valence of two. chebi_ontology a divalent metal cation CHEBI:60240 divalent metal cation CHEBI:60240 a divalent metal cation UniProt An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one. chebi_ontology a monovalent cation CHEBI:60242 monovalent inorganic cation CHEBI:60242 a monovalent cation UniProt R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives. +1 CHN3R5 55.039 55.01705 C(=[N+]([H])*)(N(*)*)N(*)* chebi_ontology diaminomethaniminium ion diaminomethaniminium ions guanidinium ions CHEBI:60251 guanidinium ion CHEBI:60251 diaminomethaniminium ion ChEBI diaminomethaniminium ions ChEBI guanidinium ions ChEBI A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*). CHEBI:76763 chebi_ontology EC 3.4.* (hydrolase acting on peptide bond) inhibitor EC 3.4.* (hydrolase acting on peptide bonds) inhibitors EC 3.4.* (hydrolases acting on peptide bond) inhibitors EC 3.4.* (peptidase) inhibitor EC 3.4.* (peptidase) inhibitors EC 3.4.* inhibitor EC 3.4.* inhibitors inhibitor of hydrolases acting on peptide bond (EC 3.4.*) inhibitors of hydrolases acting on peptide bond (EC 3.4.*) peptidase inhibitors protease inhibitor protease inhibitors CHEBI:60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor CHEBI:60258 EC 3.4.* (hydrolase acting on peptide bond) inhibitor ChEBI EC 3.4.* (hydrolase acting on peptide bonds) inhibitors ChEBI EC 3.4.* (hydrolases acting on peptide bond) inhibitors ChEBI EC 3.4.* (peptidase) inhibitor ChEBI EC 3.4.* (peptidase) inhibitors ChEBI EC 3.4.* inhibitor ChEBI EC 3.4.* inhibitors ChEBI inhibitor of hydrolases acting on peptide bond (EC 3.4.*) ChEBI inhibitors of hydrolases acting on peptide bond (EC 3.4.*) ChEBI peptidase inhibitors ChEBI protease inhibitor ChEBI protease inhibitors ChEBI A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine. 0 C6H7N3O InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10) QRXWMOHMRWLFEY-UHFFFAOYSA-N 137.13930 137.05891 NNC(=O)c1ccncc1 Beilstein:119374 CAS:54-85-3 DrugBank:DB00951 Drug_Central:1497 Gmelin:82804 KEGG:C07054 KEGG:D00346 LINCS:LSM-6682 MetaCyc:ISONIAZIDE PMID:15013786 PMID:18220565 PMID:19183459 PMID:445303 Reaxys:119374 Wikipedia:Isoniazid pyridine-4-carbohydrazide chebi_ontology 4-pyridinecarbohydrazide Isoniazid Isonicotinsaeurehydrazid isoniazid isonicotinic acid hydrazide isonicotinic hydrazide isonicotinohydrazide isonicotinoylhydrazide pyridine-4-carboxylic acid hydrazide CHEBI:6030 isoniazide CHEBI:6030 Beilstein:119374 Beilstein CAS:54-85-3 ChemIDplus CAS:54-85-3 KEGG COMPOUND CAS:54-85-3 NIST Chemistry WebBook Drug_Central:1497 DrugCentral Gmelin:82804 Gmelin PMID:15013786 Europe PMC PMID:18220565 Europe PMC PMID:19183459 Europe PMC PMID:445303 Europe PMC Reaxys:119374 Reaxys pyridine-4-carbohydrazide IUPAC 4-pyridinecarbohydrazide ChEBI Isoniazid KEGG_COMPOUND Isonicotinsaeurehydrazid ChEBI isoniazid UniProt isonicotinic acid hydrazide NIST_Chemistry_WebBook isonicotinic hydrazide ChEBI isonicotinohydrazide NIST_Chemistry_WebBook isonicotinoylhydrazide IUPAC pyridine-4-carboxylic acid hydrazide ChEBI A pyridinemonocarboxylic acid in which the carboxy group is at position 4 of the pyridine ring. 0 C6H5NO2 InChI=1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9) TWBYWOBDOCUKOW-UHFFFAOYSA-N 123.10940 123.03203 OC(=O)c1ccncc1 Beilstein:109599 CAS:55-22-1 Gmelin:68876 HMDB:HMDB0060665 KEGG:C07446 PMID:13115353 PMID:22537922 PMID:23832340 PMID:23929452 Reaxys:109599 Wikipedia:Isonicotinic_Acid Isonicotinic acid isonicotinic acid pyridine-4-carboxylic acid chebi_ontology 4-carboxypyridine 4-pyridinecarboxylic acid gamma-picolinic acid gamma-pyridinecarboxylic acid p-pyridinecarboxylic acid CHEBI:6032 isonicotinic acid CHEBI:6032 Beilstein:109599 Beilstein CAS:55-22-1 ChemIDplus CAS:55-22-1 KEGG COMPOUND CAS:55-22-1 NIST Chemistry WebBook Gmelin:68876 Gmelin PMID:13115353 Europe PMC PMID:22537922 Europe PMC PMID:23832340 Europe PMC PMID:23929452 Europe PMC Reaxys:109599 Reaxys Isonicotinic acid KEGG_COMPOUND isonicotinic acid IUPAC pyridine-4-carboxylic acid IUPAC 4-carboxypyridine NIST_Chemistry_WebBook 4-pyridinecarboxylic acid NIST_Chemistry_WebBook gamma-picolinic acid NIST_Chemistry_WebBook gamma-pyridinecarboxylic acid ChemIDplus p-pyridinecarboxylic acid ChemIDplus An anion formed by deprotonation of at least one peptide carboxy group. chebi_ontology peptide anions CHEBI:60334 peptide anion CHEBI:60334 peptide anions ChEBI Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged. 0 C2H4NO2R(C2H2NOR)n chebi_ontology a peptide peptide zwitterions CHEBI:60466 peptide zwitterion CHEBI:60466 a peptide UniProt peptide zwitterions ChEBI Compounds that contain an amide group as a key feature of their structure and which have been used as fungicides. chebi_ontology amide fungicides CHEBI:60600 amide fungicide CHEBI:60600 amide fungicides ChEBI Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. CHEBI:60797 chebi_ontology N-methyl-D-aspartate receptor antagonist N-methyl-D-aspartate receptor antagonists NMDA receptor antagonists NMDAR antagonist NMDAR antagonists CHEBI:60643 NMDA receptor antagonist CHEBI:60643 N-methyl-D-aspartate receptor antagonist ChEBI N-methyl-D-aspartate receptor antagonists ChEBI NMDA receptor antagonists ChEBI NMDAR antagonist ChEBI NMDAR antagonists ChEBI Any fatty acid containing nitrogen as either a substituent or a replacement for a methylene carbon. chebi_ontology N-containing fatty acid N-containing fatty acids nitrogen-containing fatty acids CHEBI:60690 nitrogen-containing fatty acid CHEBI:60690 N-containing fatty acid ChEBI N-containing fatty acids ChEBI nitrogen-containing fatty acids ChEBI An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. 0 C35H38Cl2N8O4 InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/m0/s1 VHVPQPYKVGDNFY-ZPGVKDDISA-N 705.63300 704.23931 CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c3ccc(Cl)cc3Cl)cc2)c1=O CAS:84625-61-6 DrugBank:DB01167 KEGG:D00350 PMID:11219548 PMID:11403818 PMID:11422002 PMID:15521894 PMID:19025521 PMID:20400651 PMID:25326091 Patent:EP6711 Patent:US4267179 VSDB:1853 Wikipedia:Itraconazole 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one Itraconazole itraconazole chebi_ontology Itrizole (TN) Oriconazole Sporanox (TN) CHEBI:6076 itraconazole CHEBI:6076 CAS:84625-61-6 ChemIDplus CAS:84625-61-6 KEGG DRUG PMID:11219548 Europe PMC PMID:11403818 Europe PMC PMID:11422002 Europe PMC PMID:15521894 Europe PMC PMID:19025521 Europe PMC PMID:20400651 Europe PMC PMID:25326091 Europe PMC 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one IUPAC Itraconazole KEGG_DRUG itraconazole UniProt Itrizole (TN) KEGG_DRUG Oriconazole ChemIDplus Sporanox (TN) KEGG_DRUG An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells. chebi_ontology nucleoside analogues CHEBI:60783 nucleoside analogue CHEBI:60783 nucleoside analogues ChEBI Any substance which inhibits the action of receptors for excitatory amino acids. chebi_ontology EAA receptor antagonist EAA receptor antagonists excitatory amino acid antagonists excitatory amino acid receptor antagonist excitatory amino acid receptor antagonists CHEBI:60798 excitatory amino acid antagonist CHEBI:60798 EAA receptor antagonist ChEBI EAA receptor antagonists ChEBI excitatory amino acid antagonists ChEBI excitatory amino acid receptor antagonist ChEBI excitatory amino acid receptor antagonists ChEBI Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself. chebi_ontology adjuvants CHEBI:60809 adjuvant CHEBI:60809 adjuvants ChEBI Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules. chebi_ontology tubulin modulators CHEBI:60832 tubulin modulator CHEBI:60832 tubulin modulators ChEBI Any alpha-amino acid anion in which the parent amino acid has D-configuration. -1 C2H3NO2R 73.051 73.01638 [C@@H](C(=O)[O-])(N)* chebi_ontology D-alpha-amino acid anions D-alpha-amino carboxylate CHEBI:60895 D-alpha-amino acid anion CHEBI:60895 D-alpha-amino acid anions ChEBI D-alpha-amino carboxylate ChEBI A racemate is an equimolar mixture of a pair of enantiomers. chebi_ontology melange racemique racemates racemic mixture CHEBI:60911 racemate CHEBI:60911 melange racemique ChEBI racemates ChEBI racemic mixture ChEBI A mixture composed of two or more diastereoisomers (stereoisomers not related as mirror images). chebi_ontology diastereomeric mixture CHEBI:60915 diastereoisomeric mixture CHEBI:60915 diastereomeric mixture ChEBI Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group. chebi_ontology amino monosaccharides CHEBI:60926 amino monosaccharide CHEBI:60926 amino monosaccharides ChEBI A glucoside in which the anomeric carbon of the glycosidic bond is in an alpha configuration chebi_ontology alpha-glucosides CHEBI:60979 alpha-glucoside CHEBI:60979 alpha-glucosides ChEBI A nitrogen-containing fatty acid anion arising from deprotonation of the carboxy group of any amino fatty acid. chebi_ontology NH2-FA anion NH2-FA anions NH2-fatty acid anion NH2-fatty acid anions amino FA anion amino FA anions amino fatty acid anions CHEBI:61007 amino fatty acid anion CHEBI:61007 NH2-FA anion ChEBI NH2-FA anions ChEBI NH2-fatty acid anion ChEBI NH2-fatty acid anions ChEBI amino FA anion ChEBI amino FA anions ChEBI amino fatty acid anions ChEBI A fatty acid anion arising from deprotonation of the carboxylic acid group of any nitrogen-containing fatty acid. nitrogen-containing fatty acid anion chebi_ontology N-containing FA anion N-containing FA anions N-containing fatty acid anions nitrogen-containing FA anion nitrogen-containing FA anions nitrogen-containing fatty acid anions CHEBI:61008 nitrogen-containing fatty acid anion CHEBI:61008 nitrogen-containing fatty acid anion ChEBI N-containing FA anion ChEBI N-containing FA anions ChEBI N-containing fatty acid anions ChEBI nitrogen-containing FA anion ChEBI nitrogen-containing FA anions ChEBI nitrogen-containing fatty acid anions ChEBI A poison that interferes with the function of the kidneys. chebi_ontology nephrotoxins CHEBI:61015 nephrotoxin CHEBI:61015 nephrotoxins ChEBI An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). Wikipedia:Histone_deacetylase_inhibitor chebi_ontology EC 3.5.1.98 (histone deacetylase) inhibitors EC 3.5.1.98 inhibitor EC 3.5.1.98 inhibitors HDAC inhibitor HDAC inhibitors HDACi HDACis HDI HDIs histone amidohydrolase inhibitor histone amidohydrolase inhibitors histone deacetylase (EC 3.5.1.98) inhibitor histone deacetylase (EC 3.5.1.98) inhibitors histone deacetylase inhibitor histone deacetylase inhibitors CHEBI:61115 EC 3.5.1.98 (histone deacetylase) inhibitor CHEBI:61115 EC 3.5.1.98 (histone deacetylase) inhibitors ChEBI EC 3.5.1.98 inhibitor ChEBI EC 3.5.1.98 inhibitors ChEBI HDAC inhibitor ChEBI HDAC inhibitors ChEBI HDACi ChEBI HDACis ChEBI HDI ChEBI HDIs ChEBI histone amidohydrolase inhibitor ChEBI histone amidohydrolase inhibitors ChEBI histone deacetylase (EC 3.5.1.98) inhibitor ChEBI histone deacetylase (EC 3.5.1.98) inhibitors ChEBI histone deacetylase inhibitor ChEBI histone deacetylase inhibitors ChEBI Any compound that has a nucleobase as a part. chebi_ontology nucleobase-containing compound nucleobase-containing compounds nucleobase-containing molecular entities CHEBI:61120 nucleobase-containing molecular entity CHEBI:61120 nucleobase-containing compound SUBMITTER nucleobase-containing compounds ChEBI nucleobase-containing molecular entities ChEBI A nucleotide having adenine as the base. chebi_ontology adenine nucleotide CHEBI:61293 adenyl nucleotide CHEBI:61293 adenine nucleotide SUBMITTER A purine riboncleotide where adenine is the purine. chebi_ontology adenine ribonucleotide CHEBI:61296 adenyl ribonucleotide CHEBI:61296 adenine ribonucleotide SUBMITTER Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. chebi_ontology amino cyclitols aminocyclitol aminocyclitols CHEBI:61689 amino cyclitol CHEBI:61689 amino cyclitols ChEBI aminocyclitol ChEBI aminocyclitols ChEBI A cyclodepsipeptide antibiotic, which is isolated from the filamentous fungus Aureobasidium pullulans R106 and is toxic to yeast at low concentrations (0.1-0.5 ug/ml). 0 C60H92N8O10 InChI=1S/C60H92N8O10/c1-17-39(12)51-55(72)63-47(36(6)7)53(70)61-44(32-41-25-20-18-21-26-41)56(73)65(14)46(33-42-27-22-19-23-28-42)58(75)68-30-24-29-45(68)52(69)64-48(40(13)35(4)5)59(76)66(15)49(37(8)9)54(71)62-43(31-34(2)3)57(74)67(16)50(38(10)11)60(77)78-51/h18-23,25-28,34-40,43-51H,17,24,29-33H2,1-16H3,(H,61,70)(H,62,71)(H,63,72)(H,64,69)/t39-,40-,43+,44+,45+,46+,47?,48-,49+,50+,51+/m1/s1 YHSKJPXGXIYLHB-OTNPUQRPSA-N 1085.42010 1084.69364 CC[C@@H](C)[C@@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)N(C)C(=O)[C@H](Cc2ccccc2)NC(=O)C(NC1=O)C(C)C)[C@H](C)C(C)C CAS:127785-64-2 (3R,6S,9S,12S,15S,21S,24S,29aS)-21,24-dibenzyl-15-[(2R)-butan-2-yl]-9-isobutyl-6,12,18-triisopropyl-5,11,23-trimethyl-3-[(2R)-3-methylbutan-2-yl]octadecahydro-1H,15H-pyrrolo[1,2-m][1,4,7,10,13,16,19,22,25]oxaoctaazacycloheptacosine-1,4,7,10,13,16,19,22,25-nonone chebi_ontology (3S,6S,9S,12S,15S,18S,21S,24R,27S)-12,24-bis[(2R)-butan-2-yl]-15-(2-hydroxypropan-2-yl)-4,10,16,22-tetramethyl-18-(2-methylpropyl)-3,6-bis(phenylmethyl)-9,21-di(propan-2-yl)-13-oxa-1,4,7,10,16,19,22,25-octazabicyclo[25.3.0]triacontane-2,5,8,11,14,17,20,23,26-nonone Antibiotic R106I N-((2R,3R)-2-hydroxy-3-methylvaleryl)-N-methyl-L-valyl-L-phenylalanyl-N-methyl-L-phenylalanyl-L-prolyl-L- alloisoleucyl-N-methyl-L-valyl-L-leucyl-3-hydroxy-N-methyl- L-valine alpha1-lactone basifungin CHEBI:61739 aureobasidin A CHEBI:61739 CAS:127785-64-2 SUBMITTER (3R,6S,9S,12S,15S,21S,24S,29aS)-21,24-dibenzyl-15-[(2R)-butan-2-yl]-9-isobutyl-6,12,18-triisopropyl-5,11,23-trimethyl-3-[(2R)-3-methylbutan-2-yl]octadecahydro-1H,15H-pyrrolo[1,2-m][1,4,7,10,13,16,19,22,25]oxaoctaazacycloheptacosine-1,4,7,10,13,16,19,22,25-nonone IUPAC (3S,6S,9S,12S,15S,18S,21S,24R,27S)-12,24-bis[(2R)-butan-2-yl]-15-(2-hydroxypropan-2-yl)-4,10,16,22-tetramethyl-18-(2-methylpropyl)-3,6-bis(phenylmethyl)-9,21-di(propan-2-yl)-13-oxa-1,4,7,10,16,19,22,25-octazabicyclo[25.3.0]triacontane-2,5,8,11,14,17,20,23,26-nonone SUBMITTER Antibiotic R106I ChEBI N-((2R,3R)-2-hydroxy-3-methylvaleryl)-N-methyl-L-valyl-L-phenylalanyl-N-methyl-L-phenylalanyl-L-prolyl-L- alloisoleucyl-N-methyl-L-valyl-L-leucyl-3-hydroxy-N-methyl- L-valine alpha1-lactone ChemIDplus basifungin ChemIDplus An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase. PMID:17420564 PMID:17420565 PMID:19644518 PMID:19644519 PMID:19662087 chebi_ontology CHEBI:61774 inositol phosphorylceramide synthase inhibitor CHEBI:61774 PMID:17420564 Europe PMC PMID:17420565 Europe PMC PMID:19644518 Europe PMC PMID:19644519 Europe PMC PMID:19662087 Europe PMC Any substance that interacts with tubulin to inhibit polymerisation of microtubules. PMID:17099073 chebi_ontology microtubule destabilising agent microtubule destabilising agents microtubule destabilising role microtubule destabilizing role microtubule-destabilising agents microtubule-destabilizing agent microtubule-destabilizing agents CHEBI:61951 microtubule-destabilising agent CHEBI:61951 PMID:17099073 Europe PMC microtubule destabilising agent ChEBI microtubule destabilising agents ChEBI microtubule destabilising role ChEBI microtubule destabilizing role SUBMITTER microtubule-destabilising agents ChEBI microtubule-destabilizing agent ChEBI microtubule-destabilizing agents ChEBI Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group. 0 C2H4NO2R 74.059 74.02420 C(C([O-])=O)(*)[NH3+] MetaCyc:Polar-amino-acids chebi_ontology a polar amino acid CHEBI:62031 polar amino acid zwitterion CHEBI:62031 MetaCyc:Polar-amino-acids SUBMITTER a polar amino acid UniProt A monocarboxylic acid anion that is the conjugate base of nalidixic acid; major species at pH 7.3. -1 C12H11N2O3 InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)/p-1 MHWLWQUZZRMNGJ-UHFFFAOYSA-M 231.22730 231.07752 CCn1cc(C([O-])=O)c(=O)c2ccc(C)nc12 PMID:10793679 PMID:16107187 PMID:375215 PMID:6283318 PMID:673862 PMID:766016 PMID:785214 PMID:8893520 Reaxys:3556893 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate chebi_ontology nalidixate nalidixate anion nalidixate(1-) nalidixylate CHEBI:62070 nalidixic acid anion CHEBI:62070 PMID:10793679 Europe PMC PMID:16107187 Europe PMC PMID:375215 Europe PMC PMID:6283318 Europe PMC PMID:673862 Europe PMC PMID:766016 Europe PMC PMID:785214 Europe PMC PMID:8893520 Europe PMC Reaxys:3556893 Reaxys 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate IUPAC nalidixate ChEBI nalidixate anion ChEBI nalidixate(1-) ChEBI nalidixylate SUBMITTER An organic cation resulting from the protonation of pyocyanin. +1 C13H11N2O InChI=1S/C13H10N2O/c1-15-10-6-3-2-5-9(10)14-13-11(15)7-4-8-12(13)16/h2-8H,1H3/p+1 YNCMLFHHXWETLD-UHFFFAOYSA-O 211.23920 211.08659 C[n+]1c2ccccc2nc2c(O)cccc12 MetaCyc:CPD-12847 PMID:14210570 PMID:1500199 PMID:17253782 PMID:19869911 PMID:2106495 PMID:2422042 PMID:2547716 PMID:3028961 PMID:3150520 PMID:415847 PMID:4202997 PMID:4977219 PMID:6243619 PMID:6774217 PMID:6782436 PMID:9078238 Reaxys:3908208 1-hydroxy-5-methylphenazin-5-ium chebi_ontology 5-methylphenazin-1(5H)-one pyocyanin pyocyanin(1+) CHEBI:62220 pyocyanine(1+) CHEBI:62220 MetaCyc:CPD-12847 SUBMITTER PMID:14210570 Europe PMC PMID:1500199 Europe PMC PMID:17253782 SUBMITTER PMID:19869911 Europe PMC PMID:2106495 Europe PMC PMID:2422042 Europe PMC PMID:2547716 Europe PMC PMID:3028961 Europe PMC PMID:3150520 Europe PMC PMID:415847 Europe PMC PMID:4202997 Europe PMC PMID:4977219 Europe PMC PMID:6243619 Europe PMC PMID:6774217 Europe PMC PMID:6782436 Europe PMC PMID:9078238 Europe PMC Reaxys:3908208 Reaxys 1-hydroxy-5-methylphenazin-5-ium IUPAC 5-methylphenazin-1(5H)-one MetaCyc pyocyanin UniProt pyocyanin(1+) ChEBI An organophosphonate oxoanion obtained by deprotonation of one of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid; major species at pH 7.3. -1 C3H6O4P InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/p-1/t2-,3+/m0/s1 YMDXZJFXQJVXBF-STHAYSLISA-M 137.05110 137.00092 C[C@@H]1O[C@@H]1P(O)([O-])=O MetaCyc:CPD0-1113 PMID:18656958 hydrogen [(2R,3S)-3-methyloxiran-2-yl]phosphonate chebi_ontology (1R,2S)-epoxypropylphosphonate fosfomycin fosfomycin(1-) CHEBI:62247 (1R,2S)-epoxypropylphosphonate(1-) CHEBI:62247 PMID:18656958 SUBMITTER hydrogen [(2R,3S)-3-methyloxiran-2-yl]phosphonate IUPAC (1R,2S)-epoxypropylphosphonate UniProt fosfomycin SUBMITTER fosfomycin(1-) ChEBI A uridine-based nucleoside-peptide antibiotic which inhibits fungal chitin biosynthesis by inhibiting chitin synthase. 0 C20H25N5O10 InChI=1S/C20H25N5O10/c1-7(13(28)9-3-2-8(26)6-22-9)11(21)17(31)24-12(19(32)33)16-14(29)15(30)18(35-16)25-5-4-10(27)23-20(25)34/h2-7,11-16,18,26,28-30H,21H2,1H3,(H,24,31)(H,32,33)(H,23,27,34)/t7-,11-,12-,13-,14-,15+,16+,18+/m0/s1 WWJFFVUVFNBJTN-VHDFTHOZSA-N 495.44000 495.16014 [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)[C@H](NC(=O)[C@@H](N)[C@H](C)[C@H](O)c1ccc(O)cn1)C(O)=O CHEBI:109145 CHEBI:621961 Beilstein:4303204 CAS:59456-70-1 PMID:10888330 PMID:12205060 PMID:12729648 PMID:1992114 PMID:19930628 PMID:20931236 PMID:22203603 Reaxys:4303204 chebi_ontology (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-beta-D-allo-furanuronic acid (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]acetic acid Neopolyoxin C Nikkomycin CHEBI:623918 nikkomycin Z CHEBI:623918 Beilstein:4303204 Beilstein CAS:59456-70-1 ChemIDplus PMID:10888330 ChEMBL PMID:12205060 Europe PMC PMID:12729648 ChEMBL PMID:1992114 ChEMBL PMID:19930628 Europe PMC PMID:20931236 Europe PMC PMID:22203603 Europe PMC Reaxys:4303204 Reaxys (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-beta-D-allo-furanuronic acid ChEBI (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]acetic acid ChEBI Neopolyoxin C ChemIDplus Nikkomycin ChemIDplus An organophosphonate oxoanion obtained by deprotonation of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid. -2 C3H5O4P InChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/p-2/t2-,3+/m0/s1 YMDXZJFXQJVXBF-STHAYSLISA-L 136.04320 135.99364 C[C@@H]1O[C@@H]1P([O-])([O-])=O PMID:10681332 PMID:18656958 PMID:3637200 PMID:3782953 PMID:3900283 PMID:6357073 PMID:6440482 PMID:6725145 PMID:6739142 PMID:832538 [(2R,3S)-3-methyloxiran-2-yl]phosphonate chebi_ontology (1R,2S)-epoxypropylphosphonate (1R,2S)-epoxypropylphosphonate dianion fosfomycin fosfomycin dianion fosfomycin(2-) CHEBI:62419 (1R,2S)-epoxypropylphosphonate(2-) CHEBI:62419 PMID:10681332 Europe PMC PMID:18656958 Europe PMC PMID:3637200 Europe PMC PMID:3782953 Europe PMC PMID:3900283 Europe PMC PMID:6357073 Europe PMC PMID:6440482 Europe PMC PMID:6725145 Europe PMC PMID:6739142 Europe PMC PMID:832538 Europe PMC [(2R,3S)-3-methyloxiran-2-yl]phosphonate IUPAC (1R,2S)-epoxypropylphosphonate ChEBI (1R,2S)-epoxypropylphosphonate dianion ChEBI fosfomycin ChEBI fosfomycin dianion ChEBI fosfomycin(2-) ChEBI A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. chebi_ontology signal molecule signal molecules signaling molecule signaling molecules signalling molecules CHEBI:62488 signalling molecule CHEBI:62488 signal molecule ChEBI signal molecules ChEBI signaling molecule ChEBI signaling molecules ChEBI signalling molecules ChEBI Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-). chebi_ontology anionic phospholipids phospholipid anion phospholipid anions CHEBI:62643 anionic phospholipid CHEBI:62643 anionic phospholipids ChEBI phospholipid anion ChEBI phospholipid anions ChEBI An amide in which the amide linkage is bonded directly to an aromatic system. chebi_ontology aromatic amides CHEBI:62733 aromatic amide CHEBI:62733 aromatic amides ChEBI Any compound that is able to prevent damage to the liver. chebi_ontology antihepatotoxic agent hepatoprotective agents hepatoprotector CHEBI:62868 hepatoprotective agent CHEBI:62868 antihepatotoxic agent ChEBI hepatoprotective agents ChEBI hepatoprotector ChEBI An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1). Wikipedia:Aldehyde_oxidase chebi_ontology EC 1.2.3.1 (aldehyde oxidase) inhibitors EC 1.2.3.1 inhibitor EC 1.2.3.1 inhibitors aldehyde oxidase (EC 1.2.3.1) inhibitor aldehyde oxidase (EC 1.2.3.1) inhibitors aldehyde oxidase inhibitor aldehyde oxidase inhibitors aldehyde:oxygen oxidoreductase inhibitor aldehyde:oxygen oxidoreductase inhibitors quinoline oxidase inhibitor quinoline oxidase inhibitors retinal oxidase inhibitor retinal oxidase inhibitors retinoic acid synthase inhibitor retinoic acid synthase inhibitors CHEBI:62872 EC 1.2.3.1 (aldehyde oxidase) inhibitor CHEBI:62872 EC 1.2.3.1 (aldehyde oxidase) inhibitors ChEBI EC 1.2.3.1 inhibitor ChEBI EC 1.2.3.1 inhibitors ChEBI aldehyde oxidase (EC 1.2.3.1) inhibitor ChEBI aldehyde oxidase (EC 1.2.3.1) inhibitors ChEBI aldehyde oxidase inhibitor ChEBI aldehyde oxidase inhibitors ChEBI aldehyde:oxygen oxidoreductase inhibitor ChEBI aldehyde:oxygen oxidoreductase inhibitors ChEBI quinoline oxidase inhibitor ChEBI quinoline oxidase inhibitors ChEBI retinal oxidase inhibitor ChEBI retinal oxidase inhibitors ChEBI retinoic acid synthase inhibitor ChEBI retinoic acid synthase inhibitors ChEBI An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30). Wikipedia:PARP_inhibitor chebi_ontology ADP-ribosyltransferase (polymerising) inhibitor ADP-ribosyltransferase (polymerising) inhibitors ADP-ribosyltransferase (polymerizing) inhibitor ADP-ribosyltransferase (polymerizing) inhibitors EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors EC 2.4.2.30 inhibitor EC 2.4.2.30 inhibitors NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors NAD(+) ADP-ribosyltransferase inhibitor NAD(+) ADP-ribosyltransferase inhibitors NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors PARP PARPs poly(ADP-ribose) polymerase inhibitor poly(ADP-ribose) polymerase inhibitors poly(ADP-ribose) synthase inhibitor poly(ADP-ribose) synthase inhibitors poly(ADP-ribose) synthetase inhibitor poly(ADP-ribose) synthetase inhibitors poly(adenosine diphosphate ribose) polymerase inhibitor poly(adenosine diphosphate ribose) polymerase inhibitors CHEBI:62913 EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor CHEBI:62913 ADP-ribosyltransferase (polymerising) inhibitor ChEBI ADP-ribosyltransferase (polymerising) inhibitors ChEBI ADP-ribosyltransferase (polymerizing) inhibitor ChEBI ADP-ribosyltransferase (polymerizing) inhibitors ChEBI EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors ChEBI EC 2.4.2.30 inhibitor ChEBI EC 2.4.2.30 inhibitors ChEBI NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor ChEBI NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors ChEBI NAD(+) ADP-ribosyltransferase inhibitor ChEBI NAD(+) ADP-ribosyltransferase inhibitors ChEBI NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor ChEBI NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors ChEBI NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor ChEBI NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors ChEBI PARP ChEBI PARPs ChEBI poly(ADP-ribose) polymerase inhibitor ChEBI poly(ADP-ribose) polymerase inhibitors ChEBI poly(ADP-ribose) synthase inhibitor ChEBI poly(ADP-ribose) synthase inhibitors ChEBI poly(ADP-ribose) synthetase inhibitor ChEBI poly(ADP-ribose) synthetase inhibitors ChEBI poly(adenosine diphosphate ribose) polymerase inhibitor ChEBI poly(adenosine diphosphate ribose) polymerase inhibitors ChEBI The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability. chebi_ontology emulgent emulgents emulsifiers CHEBI:63046 emulsifier CHEBI:63046 emulgent ChEBI emulgents ChEBI emulsifiers ChEBI A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity. chebi_ontology glycosyl compounds CHEBI:63161 glycosyl compound CHEBI:63161 glycosyl compounds ChEBI The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species. Wikipedia:Reducing_agent chebi_ontology reducer reducers reducing agents reductant reductants CHEBI:63247 reducing agent CHEBI:63247 reducer ChEBI reducers ChEBI reducing agents ChEBI reductant ChEBI reductants ChEBI A substance that removes electrons from another reactant in a redox reaction. chebi_ontology oxidant oxidants oxidiser oxidisers oxidising agents oxidizer oxidizers oxidizing agent oxidizing agents CHEBI:63248 oxidising agent CHEBI:63248 oxidant ChEBI oxidants ChEBI oxidiser ChEBI oxidisers ChEBI oxidising agents ChEBI oxidizer ChEBI oxidizers ChEBI oxidizing agent ChEBI oxidizing agents ChEBI Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. chebi_ontology carbohydrate derivatives derivatised carbohydrate derivatised carbohydrates derivatized carbohydrate derivatized carbohydrates CHEBI:63299 carbohydrate derivative CHEBI:63299 carbohydrate derivatives ChEBI derivatised carbohydrate ChEBI derivatised carbohydrates ChEBI derivatized carbohydrate ChEBI derivatized carbohydrates ChEBI A carbohydrate derivative that is formally obtained from a disaccharide. chebi_ontology disaccharide derivatives CHEBI:63353 disaccharide derivative CHEBI:63353 disaccharide derivatives ChEBI A carbohydrate derivative that is formally obtained from a monosaccharide. chebi_ontology monosaccharide derivatives CHEBI:63367 monosaccharide derivative CHEBI:63367 monosaccharide derivatives ChEBI A monosaccharide derivative that is formally obtained from a pentose. chebi_ontology pentose derivatives CHEBI:63409 pentose derivative CHEBI:63409 pentose derivatives ChEBI An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated). chebi_ontology aromatic amino-acid anions CHEBI:63473 aromatic amino-acid anion CHEBI:63473 aromatic amino-acid anions ChEBI A substance capable of undergoing rapid and highly exothermic decomposition. Wikipedia:Explosive_material chebi_ontology explosive compound explosive compounds explosive material explosives explosives chemical explosives chemicals CHEBI:63490 explosive CHEBI:63490 explosive compound ChEBI explosive compounds ChEBI explosive material ChEBI explosives ChEBI explosives chemical ChEBI explosives chemicals ChEBI An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase. 0 C18H20FN3O4 InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1 GSDSWSVVBLHKDQ-JTQLQIEISA-N 361.373 361.14378 C[C@H]1COC2=C(N3CCN(C)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=O CHEBI:6440 CAS:100986-85-4 DrugBank:DB01137 Drug_Central:1569 HMDB:HMDB0001929 KEGG:C07660 KEGG:D08120 LINCS:LSM-5270 PDBeChem:LFX PMID:10803495 PMID:11141388 PMID:11181130 PMID:11249554 PMID:11558453 PMID:11898264 PMID:11975700 PMID:14581720 PMID:15969945 PMID:17549677 PMID:19212411 PMID:20596531 PMID:2079448 PMID:21075586 PMID:21965436 PMID:21974858 PMID:22088660 PMID:22221614 PMID:23965305 PMID:26792525 PMID:27050128 PMID:34323366 PMID:34824229 PMID:36076992 PMID:36102678 PMID:36119964 PMID:36135690 PMID:36314364 PMID:36328279 PMID:8656585 PMID:8957581 PMID:9068926 PMID:9624783 Reaxys:5385660 VSDB:1899 Wikipedia:Levofloxacin (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid chebi_ontology (-)-Ofloxacin (-)-ofloxacin (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid (S)-ofloxacin DR 3355 DR-3355 L-ofloxacin Ofloxacin S-(-)-form S-(-)-ofloxacin levofloxacin levofloxacine levofloxacino levofloxacinum CHEBI:63598 levofloxacin CHEBI:63598 CAS:100986-85-4 ChemIDplus CAS:100986-85-4 KEGG COMPOUND Drug_Central:1569 DrugCentral PMID:10803495 Europe PMC PMID:11141388 Europe PMC PMID:11181130 Europe PMC PMID:11249554 Europe PMC PMID:11558453 Europe PMC PMID:11898264 Europe PMC PMID:11975700 Europe PMC PMID:14581720 Europe PMC PMID:15969945 Europe PMC PMID:17549677 Europe PMC PMID:19212411 Europe PMC PMID:20596531 Europe PMC PMID:2079448 Europe PMC PMID:21075586 Europe PMC PMID:21965436 Europe PMC PMID:21974858 Europe PMC PMID:22088660 Europe PMC PMID:22221614 Europe PMC PMID:23965305 Europe PMC PMID:26792525 Europe PMC PMID:27050128 Europe PMC PMID:34323366 Europe PMC PMID:34824229 Europe PMC PMID:36076992 Europe PMC PMID:36102678 Europe PMC PMID:36119964 Europe PMC PMID:36135690 Europe PMC PMID:36314364 Europe PMC PMID:36328279 Europe PMC PMID:8656585 Europe PMC PMID:8957581 Europe PMC PMID:9068926 Europe PMC PMID:9624783 Europe PMC Reaxys:5385660 Reaxys (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid IUPAC (-)-Ofloxacin ChemIDplus (-)-ofloxacin ChEBI (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid ChEBI (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid ChEBI (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid ChemIDplus (S)-ofloxacin ChemIDplus DR 3355 ChEBI DR-3355 ChEBI L-ofloxacin DrugBank Ofloxacin S-(-)-form KEGG_COMPOUND S-(-)-ofloxacin ChEBI levofloxacin KEGG_DRUG levofloxacine ChemIDplus levofloxacino ChemIDplus levofloxacinum ChemIDplus An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex. 0 C16H20FN3O4 InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 337.34610 337.14378 CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCOCC2)c(F)c1 CHEBI:6477 CAS:165800-03-3 DrugBank:DB00601 Drug_Central:1584 KEGG:C08146 KEGG:D00947 LINCS:LSM-5750 PDBeChem:ZLD PMID:21740298 PMID:21815204 PMID:21899392 PMID:22037854 PMID:22064533 PMID:22064542 PMID:22110086 PMID:22134348 PMID:22139199 PMID:22214776 PMID:22230331 PMID:22247123 Patent:US5688792 Patent:WO957271 Reaxys:7496939 Wikipedia:Linezolid Linezolid N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide chebi_ontology N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide linezolid CHEBI:63607 linezolid CHEBI:63607 CAS:165800-03-3 ChemIDplus CAS:165800-03-3 KEGG COMPOUND Drug_Central:1584 DrugCentral PMID:21740298 Europe PMC PMID:21815204 Europe PMC PMID:21899392 Europe PMC PMID:22037854 Europe PMC PMID:22064533 Europe PMC PMID:22064542 Europe PMC PMID:22110086 Europe PMC PMID:22134348 Europe PMC PMID:22139199 Europe PMC PMID:22214776 Europe PMC PMID:22230331 Europe PMC PMID:22247123 Europe PMC Reaxys:7496939 Reaxys Linezolid KEGG_COMPOUND N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide IUPAC N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide ChemIDplus linezolid KEGG_DRUG A quinolone that consists of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents. 0 C21H24FN3O4 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N 401.43140 401.17508 [H][C@@]12CCCN[C@]1([H])CN(C2)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 CHEBI:7007 CAS:151096-09-2 DrugBank:DB00218 Drug_Central:1854 KEGG:C07663 KEGG:D08237 LINCS:LSM-5746 Patent:EP550903 Reaxys:8365827 VSDB:2983 Wikipedia:Moxifloxacin 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Moxifloxacin chebi_ontology 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid moxifloxacin CHEBI:63611 moxifloxacin CHEBI:63611 CAS:151096-09-2 ChemIDplus CAS:151096-09-2 KEGG COMPOUND Drug_Central:1854 DrugCentral Reaxys:8365827 Reaxys 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid IUPAC Moxifloxacin KEGG_COMPOUND 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid ChemIDplus moxifloxacin ChemIDplus An antogonist that blocks chemokine receptor 5 (CCR5). Wikipedia:CCR5 chebi_ontology C-C chemokine receptor 5 antagonist C-C chemokine receptor 5 antagonists CCR-5 antagonist CCR-5 antagonists CCR5 antagonist CCR5 antagonists chemokine receptor 5 antagonists CHEBI:63673 chemokine receptor 5 antagonist CHEBI:63673 C-C chemokine receptor 5 antagonist ChEBI C-C chemokine receptor 5 antagonists ChEBI CCR-5 antagonist ChEBI CCR-5 antagonists ChEBI CCR5 antagonist ChEBI CCR5 antagonists ChEBI chemokine receptor 5 antagonists ChEBI Any organic heterobicyclic compound containing ortho-fused pyrrolidine and piperidine rings. chebi_ontology CHEBI:63697 pyrrolidinopiperidine CHEBI:63697 An organic cation obtained by protonation of moxifloxacin. +1 C21H25FN3O4 InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/p+1/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-O 402.43930 402.18236 [H+].[H][C@@]12CCCN[C@]1([H])CN(C2)c1c(F)cc2c(c1OC)n(cc(C(O)=O)c2=O)C1CC1 chebi_ontology moxifloxacin cation moxifloxacin(1+) moxifloxacinium moxifloxacinium cation CHEBI:63699 moxifloxacinium(1+) CHEBI:63699 moxifloxacin cation ChEBI moxifloxacin(1+) ChEBI moxifloxacinium ChEBI moxifloxacinium cation ChEBI Any compound that can be used for the treatment of neurodegenerative disorders. chebi_ontology neuroprotectant neuroprotectants neuroprotective agents CHEBI:63726 neuroprotective agent CHEBI:63726 neuroprotectant ChEBI neuroprotectants ChEBI neuroprotective agents ChEBI Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule. CHEBI:50333 chebi_ontology macrocyclic lactones CHEBI:63944 macrocyclic lactone CHEBI:63944 macrocyclic lactones ChEBI An agonist at the estrogen receptor. chebi_ontology estrogen receptor agonists CHEBI:63951 estrogen receptor agonist CHEBI:63951 estrogen receptor agonists ChEBI Any substance which is added to food to preserve or enhance its flavour and/or appearance. Wikipedia:Food_additive chebi_ontology food additives CHEBI:64047 food additive CHEBI:64047 food additives ChEBI A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. Wikipedia:Acidity_regulator chebi_ontology acidity regulator acidity regulators food acidity regulators pH control agent pH control agents CHEBI:64049 food acidity regulator CHEBI:64049 acidity regulator ChEBI acidity regulators ChEBI food acidity regulators ChEBI pH control agent ChEBI pH control agents ChEBI An organic heterotricyclic compound comprising a pyrazine ring fused to an indole ring system. chebi_ontology pyrazinoindoles CHEBI:64130 pyrazinoindole CHEBI:64130 pyrazinoindoles ChEBI An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. Wikipedia:Farnesyltransferase chebi_ontology EC 2.5.1.58 (protein farnesyltransferase) inhibitors EC 2.5.1.58 inhibitor EC 2.5.1.58 inhibitors FTase inhibitor FTase inhibitors farnesyl transferase inhibitor farnesyl transferase inhibitors farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors farnesyltransferase inhibitor farnesyltransferase inhibitors protein farnesyltransferase (EC 2.5.1.58) inhibitor protein farnesyltransferase (EC 2.5.1.58) inhibitors protein farnesyltransferase inhibitor protein farnesyltransferase inhibitors CHEBI:64133 EC 2.5.1.58 (protein farnesyltransferase) inhibitor CHEBI:64133 EC 2.5.1.58 (protein farnesyltransferase) inhibitors ChEBI EC 2.5.1.58 inhibitor ChEBI EC 2.5.1.58 inhibitors ChEBI FTase inhibitor ChEBI FTase inhibitors ChEBI farnesyl transferase inhibitor ChEBI farnesyl transferase inhibitors ChEBI farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor ChEBI farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors ChEBI farnesyltransferase inhibitor ChEBI farnesyltransferase inhibitors ChEBI protein farnesyltransferase (EC 2.5.1.58) inhibitor ChEBI protein farnesyltransferase (EC 2.5.1.58) inhibitors ChEBI protein farnesyltransferase inhibitor ChEBI protein farnesyltransferase inhibitors ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C36H58N4O16 InChI=1S/C36H58N4O16/c1-17(2)11-9-7-5-4-6-8-10-12-22(44)38-25-29(49)26(46)20(53-35(25)56-34-24(37-18(3)42)28(48)27(47)21(16-41)54-34)15-19(43)32-30(50)31(51)33(55-32)40-14-13-23(45)39-36(40)52/h10,12-14,17,19-21,24-35,41,43,46-51H,4-9,11,15-16H2,1-3H3,(H,37,42)(H,38,44)(H,39,45,52)/b12-10+/t19-,20-,21-,24-,25-,26+,27-,28-,29-,30+,31-,32-,33-,34-,35+/m1/s1 FIIRBPHYBLFBSD-MZPZZZQLSA-N 802.86290 802.38478 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-11-methyldodec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(11-methyldodec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology tunicamycin I CHEBI:64228 tunicamycin A0 CHEBI:64228 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-11-methyldodec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(11-methyldodec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin I ChEBI An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins. chebi_ontology EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors EC 2.7.8.15 inhibitor EC 2.7.8.15 inhibitors GlcNAc-1-P transferase inhibitor GlcNAc-1-P transferase inhibitors N-acetylglucosamine phosphotransferase inhibitor N-acetylglucosamine transferase inhibitors N-acetylglucosamine-1-phosphate transferase inhibitor N-acetylglucosamine-1-phosphate transferase inhibitors UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors chitobiosylpyrophosphoryldolichol synthase inhibitor chitobiosylpyrophosphoryldolichol synthase inhibitors dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors CHEBI:64237 EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor CHEBI:64237 EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors ChEBI EC 2.7.8.15 inhibitor ChEBI EC 2.7.8.15 inhibitors ChEBI GlcNAc-1-P transferase inhibitor ChEBI GlcNAc-1-P transferase inhibitors ChEBI N-acetylglucosamine phosphotransferase inhibitor ChEBI N-acetylglucosamine transferase inhibitors ChEBI N-acetylglucosamine-1-phosphate transferase inhibitor ChEBI N-acetylglucosamine-1-phosphate transferase inhibitors ChEBI UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor ChEBI UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors ChEBI UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor ChEBI UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors ChEBI UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor ChEBI UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors ChEBI UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor ChEBI UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors ChEBI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor ChEBI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors ChEBI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor ChEBI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors ChEBI UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor ChEBI UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors ChEBI UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor ChEBI UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors ChEBI chitobiosylpyrophosphoryldolichol synthase inhibitor ChEBI chitobiosylpyrophosphoryldolichol synthase inhibitors ChEBI dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor ChEBI dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors ChEBI uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor ChEBI uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C37H60N4O16 InChI=1S/C37H60N4O16/c1-18(2)12-10-8-6-4-5-7-9-11-13-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(3)43)29(49)28(48)22(17-42)55-35)16-20(44)33-31(51)32(52)34(56-33)41-15-14-24(46)40-37(41)53/h11,13-15,18,20-22,25-36,42,44,47-52H,4-10,12,16-17H2,1-3H3,(H,38,43)(H,39,45)(H,40,46,53)/b13-11+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1 YJQCOFNZVFGCAF-LLXUUZRASA-N 816.88950 816.40043 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 Reaxys:8183793 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-12-methyltridec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(12-methyltridec-2-enamido)-beta-D-galactopyranos-6-yl]uridine tunicamycin A1 chebi_ontology tunicamycin C tunicamycin II CHEBI:64245 tunicamycin A1 CHEBI:64245 PMID:7061468 Europe PMC Reaxys:8183793 Reaxys (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-12-methyltridec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(12-methyltridec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin A1 UniProt tunicamycin C ChEBI tunicamycin II ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C37H60N4O16 InChI=1S/C37H60N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(2)43)29(49)28(48)22(18-42)55-35)17-20(44)33-31(51)32(52)34(56-33)41-16-15-24(46)40-37(41)53/h13-16,20-22,25-36,42,44,47-52H,3-12,17-18H2,1-2H3,(H,38,43)(H,39,45)(H,40,46,53)/b14-13+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1 MMDMXWRRAOLMDC-ZNZAGFTISA-N 816.88950 816.40043 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]tetradec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(tetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology tunicamycin III CHEBI:64246 tunicamycin A2 CHEBI:64246 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]tetradec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(tetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin III ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C38H62N4O16 InChI=1S/C38H62N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(2)44)30(50)29(49)23(19-43)56-36)18-21(45)34-32(52)33(53)35(57-34)42-17-16-25(47)41-38(42)54/h14-17,21-23,26-37,43,45,48-53H,3-13,18-19H2,1-2H3,(H,39,44)(H,40,46)(H,41,47,54)/b15-14+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1 QYVMTFXNKNWWFX-YGTZKZKGSA-N 830.91610 830.41608 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]pentadec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(pentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology tunicamycin IV CHEBI:64248 tunicamycin B1 CHEBI:64248 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]pentadec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(pentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin IV ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C38H62N4O16 InChI=1S/C38H62N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h12,14-16,19,21-23,26-37,43,45,48-53H,4-11,13,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/b14-12+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1 MEYZYGMYMLNUHJ-DIRMKAHISA-N 830.91610 830.41608 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 Reaxys:5711197 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology tunicamycin A tunicamycin V CHEBI:64250 tunicamycin B2 CHEBI:64250 PMID:7061468 Europe PMC Reaxys:5711197 Reaxys (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin A ChEBI tunicamycin V ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C38H64N4O16 InChI=1S/C38H64N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h15-16,19,21-23,26-37,43,45,48-53H,4-14,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1 XAFNQFHOQPRGAK-KTVOANSYSA-N 832.93200 832.43173 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradecanamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradecanamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology tunicamycin VI CHEBI:64255 tunicamycin B3 CHEBI:64255 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradecanamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradecanamido)-beta-D-galactopyranos-6-yl]uridine IUPAC tunicamycin VI ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C39H64N4O16 InChI=1S/C39H64N4O16/c1-20(2)14-12-10-8-6-4-5-7-9-11-13-15-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(3)45)31(51)30(50)24(19-44)57-37)18-22(46)35-33(53)34(54)36(58-35)43-17-16-26(48)42-39(43)55/h13,15-17,20,22-24,27-38,44,46,49-54H,4-12,14,18-19H2,1-3H3,(H,40,45)(H,41,47)(H,42,48,55)/b15-13+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1 ZOCXUHJGZXXIGQ-NPXWYGMKSA-N 844.94270 844.43173 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O CAS:66081-36-5 Chemspider:27471426 MetaCyc:CPD-19373 PMID:29844049 PMID:29973921 PMID:30445836 PMID:33636028 PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-14-methylpentadec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(14-methylpentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology corynetoxin U-16I tunicamycin B tunicamycin VII CHEBI:64256 tunicamycin C1 CHEBI:64256 CAS:66081-36-5 ChemIDplus PMID:29844049 Europe PMC PMID:29973921 Europe PMC PMID:30445836 Europe PMC PMID:33636028 Europe PMC PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-14-methylpentadec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(14-methylpentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC corynetoxin U-16I ChemIDplus tunicamycin B ChEBI tunicamycin VII ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C39H64N4O16 InChI=1S/C39H64N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(2)45)31(51)30(50)24(20-44)57-37)19-22(46)35-33(53)34(54)36(58-35)43-18-17-26(48)42-39(43)55/h15-18,22-24,27-38,44,46,49-54H,3-14,19-20H2,1-2H3,(H,40,45)(H,41,47)(H,42,48,55)/b16-15+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1 NKDRZEIENXWUCE-VDIUWDQWSA-N 844.94270 844.43173 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]hexadec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(hexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology CHEBI:64257 tunicamycin C2 CHEBI:64257 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]hexadec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(hexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC An erythromycin cation that is the conjugate acid of erythromycin A, arising from protonation of the tertiary amino group on the 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residue; major species at pH 7.3. +1 C37H68NO13 InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/p+1/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 ULGZDMOVFRHVEP-RWJQBGPGSA-O 734.93470 734.46852 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)[NH+](C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O MetaCyc:CPD-13804 chebi_ontology erythromycin A erythromycin A cation CHEBI:64268 erythromycin A(1+) CHEBI:64268 MetaCyc:CPD-13804 SUBMITTER erythromycin A UniProt erythromycin A cation ChEBI A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C40H66N4O16 InChI=1S/C40H66N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(2)46)32(52)31(51)25(21-45)58-38)20-23(47)36-34(54)35(55)37(59-36)44-19-18-27(49)43-40(44)56/h16-19,23-25,28-39,45,47,50-55H,3-15,20-21H2,1-2H3,(H,41,46)(H,42,48)(H,43,49,56)/b17-16+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1 DYGXSHBNTGWENQ-YTXMDVFISA-N 858.96920 858.44738 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]heptadec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(heptadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology CHEBI:64271 tunicamycin D1 CHEBI:64271 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]heptadec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(heptadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. 0 C40H66N4O16 InChI=1S/C40H66N4O16/c1-21(2)15-13-11-9-7-5-4-6-8-10-12-14-16-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(3)46)32(52)31(51)25(20-45)58-38)19-23(47)36-34(54)35(55)37(59-36)44-18-17-27(49)43-40(44)56/h14,16-18,21,23-25,28-39,45,47,50-55H,4-13,15,19-20H2,1-3H3,(H,41,46)(H,42,48)(H,43,49,56)/b16-14+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1 XCEPHNBEHQJSSB-LGJGITPNSA-N 858.96920 858.44738 [H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\C=C\CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O PMID:7061468 (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-15-methylhexadec-2-enamide (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(15-methylhexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine chebi_ontology CHEBI:64272 tunicamycin D2 CHEBI:64272 PMID:7061468 Europe PMC (2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-15-methylhexadec-2-enamide IUPAC (5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(15-methylhexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine IUPAC An organic cation obtained by protonation of any erythromycin. erythromycin cation chebi_ontology CHEBI:64290 erythromycin cation CHEBI:64290 erythromycin cation ChEBI An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug. 0 C37H42F2N8O4 InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1 RAGOYPUPXAKGKH-XAKZXMRKSA-N 700.77740 700.32971 CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O CAS:171228-49-2 DrugBank:DB01263 Drug_Central:3483 KEGG:D02555 PMID:21762211 PMID:21967490 PMID:22058198 PMID:22176629 PMID:22215361 PMID:22215487 PMID:22286158 PMID:22290952 PMID:22303909 PMID:22324990 PMID:22330929 PMID:22380765 PMID:22391464 PMID:22391534 PMID:22427614 Patent:US5661151 Patent:WO9517407 Reaxys:8379448 Wikipedia:Posaconazole 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol posaconazole chebi_ontology Noxafil SCH56592 Sch 56592 Schering 56592 posaconazole CHEBI:64355 posaconazole CHEBI:64355 CAS:171228-49-2 ChemIDplus CAS:171228-49-2 KEGG DRUG Drug_Central:3483 DrugCentral PMID:21762211 Europe PMC PMID:21967490 Europe PMC PMID:22058198 Europe PMC PMID:22176629 Europe PMC PMID:22215361 Europe PMC PMID:22215487 Europe PMC PMID:22286158 Europe PMC PMID:22290952 Europe PMC PMID:22303909 Europe PMC PMID:22324990 Europe PMC PMID:22330929 Europe PMC PMID:22380765 Europe PMC PMID:22391464 Europe PMC PMID:22391534 Europe PMC PMID:22427614 Europe PMC Reaxys:8379448 Reaxys 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol IUPAC posaconazole UniProt Noxafil DrugBank SCH56592 ChEBI Sch 56592 ChemIDplus Schering 56592 ChEBI posaconazole KEGG_DRUG A carboxamidinium ion obtained by protonation of both amindino groups of pentamidine. +2 C19H26N4O2 InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)/p+2 XDRYMKDFEDOLFX-UHFFFAOYSA-P 342.43420 342.20448 NC(=[NH2+])c1ccc(OCCCCCOc2ccc(cc2)C(N)=[NH2+])cc1 [pentane-1,5-diylbis(oxy-4,1-phenylene)]bis(aminomethaniminium) chebi_ontology pentamidine dication pentamidine(2+) pentamidinium cation pentamidinium dication CHEBI:64383 pentamidinium(2+) CHEBI:64383 [pentane-1,5-diylbis(oxy-4,1-phenylene)]bis(aminomethaniminium) IUPAC pentamidine dication ChEBI pentamidine(2+) ChEBI pentamidinium cation ChEBI pentamidinium dication ChEBI An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond. chebi_ontology biaryls CHEBI:64459 biaryl CHEBI:64459 biaryls ChEBI An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. chebi_ontology N-methyl-D-aspartate receptor agonist N-methyl-D-aspartate receptor agonists NMDA receptor agonists NMDAR agonist NMDAR agonists CHEBI:64571 NMDA receptor agonist CHEBI:64571 N-methyl-D-aspartate receptor agonist ChEBI N-methyl-D-aspartate receptor agonists ChEBI NMDA receptor agonists ChEBI NMDAR agonist ChEBI NMDAR agonists ChEBI A food additive which is added to flour or dough to improve baking quality and/or colour. Wikipedia:Flour_treatment_agent flour treatment agent chebi_ontology dough improver dough improvers improving agent improving agents CHEBI:64577 flour treatment agent CHEBI:64577 flour treatment agent ChEBI dough improver ChEBI dough improvers ChEBI improving agent ChEBI improving agents ChEBI An inorganic cation with a valency of two. chebi_ontology CHEBI:64641 divalent inorganic cation CHEBI:64641 An organic molecular entity containing a single carbon atom (C1). chebi_ontology one-carbon compounds CHEBI:64708 one-carbon compound CHEBI:64708 one-carbon compounds ChEBI Any organic molecular entity that is acidic and contains carbon in covalent linkage. chebi_ontology organic acids CHEBI:64709 organic acid CHEBI:64709 organic acids ChEBI A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis. 0 C18H34N2O6S InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 406.53700 406.21376 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O CAS:154-21-2 DrugBank:DB01627 Drug_Central:1582 HMDB:HMDB0015564 KEGG:C06812 KEGG:C14002 KEGG:D00223 KEGG:D02346 LINCS:LSM-5602 PMID:24324587 Reaxys:707677 Wikipedia:Lincomycin Lincomycin methyl 6,8-dideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-erythro-alpha-D-galacto-octopyranoside chebi_ontology Cillimycin Methyl 6,8-dideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-alpha-D-galacto-octopyranoside lincomicina lincomycin lincomycine lincomycinum CHEBI:6472 lincomycin CHEBI:6472 CAS:154-21-2 ChemIDplus CAS:154-21-2 KEGG COMPOUND Drug_Central:1582 DrugCentral PMID:24324587 Europe PMC Reaxys:707677 Reaxys Lincomycin KEGG_COMPOUND methyl 6,8-dideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-erythro-alpha-D-galacto-octopyranoside IUPAC Cillimycin ChemIDplus Methyl 6,8-dideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-alpha-D-galacto-octopyranoside NIST_Chemistry_WebBook lincomicina ChemIDplus lincomycin WHO_MedNet lincomycine ChemIDplus lincomycinum ChemIDplus A group that carries an overall positive charge. chebi_ontology cationic groups CHEBI:64766 cationic group CHEBI:64766 cationic groups ChEBI A group that carries an overall negative charge. chebi_ontology anionic groups CHEBI:64767 anionic group CHEBI:64767 anionic groups ChEBI A cationic group that contains carbon. chebi_ontology organic cationic groups CHEBI:64769 organic cationic group CHEBI:64769 organic cationic groups ChEBI An anionic group that contains carbon. chebi_ontology organic anionic groups CHEBI:64775 organic anionic group CHEBI:64775 organic anionic groups ChEBI An amino-acid residue carrying an overall negative charge. chebi_ontology amino acid anion residue amino acid anion residues amino-acid anion residue amino-acid anion residues anionic amino acid residue anionic amino acid residues anionic amino-acid residues CHEBI:64898 anionic amino-acid residue CHEBI:64898 amino acid anion residue ChEBI amino acid anion residues ChEBI amino-acid anion residue ChEBI amino-acid anion residues ChEBI anionic amino acid residue ChEBI anionic amino acid residues ChEBI anionic amino-acid residues ChEBI Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. Wikipedia:Poison chebi_ontology poisonous agent poisonous agents poisonous substance poisonous substances poisons toxic agent toxic agents toxic substance toxic substances CHEBI:64909 poison CHEBI:64909 poisonous agent ChEBI poisonous agents ChEBI poisonous substance ChEBI poisonous substances ChEBI poisons ChEBI toxic agent ChEBI toxic agents ChEBI toxic substance ChEBI toxic substances ChEBI Any compound that inhibits cell division (mitosis). Wikipedia:Mitotic_inhibitor chebi_ontology antimitotics mitosis inhibitor mitosis inhibitors mitotic inhibitor mitotic inhibitors CHEBI:64911 antimitotic CHEBI:64911 antimitotics ChEBI mitosis inhibitor ChEBI mitosis inhibitors ChEBI mitotic inhibitor ChEBI mitotic inhibitors ChEBI A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy. chebi_ontology antimycobacterial agent antimycobacterial agents antimycobacterial drugs antimycobacterials antimycobacterium CHEBI:64912 antimycobacterial drug CHEBI:64912 antimycobacterial agent ChEBI antimycobacterial agents ChEBI antimycobacterial drugs ChEBI antimycobacterials ChEBI antimycobacterium ChEBI An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. chebi_ontology antiplasmodial agent antiplasmodial agents antiplasmodial drugs antiplasmodium agent antiplasmodium agents antiplasmodium drug antiplasmodium drugs CHEBI:64915 antiplasmodial drug CHEBI:64915 antiplasmodial agent ChEBI antiplasmodial agents ChEBI antiplasmodial drugs ChEBI antiplasmodium agent ChEBI antiplasmodium agents ChEBI antiplasmodium drug ChEBI antiplasmodium drugs ChEBI A depigmentation agent which inhibits the synthesis of melanin. chebi_ontology melanin biosynthesis inhibitor melanin biosynthesis inhibitors melanin synthesis inhibitors melanogenesis inhibitor melanogenesis inhibitors CHEBI:64933 melanin synthesis inhibitor CHEBI:64933 melanin biosynthesis inhibitor ChEBI melanin biosynthesis inhibitors ChEBI melanin synthesis inhibitors ChEBI melanogenesis inhibitor ChEBI melanogenesis inhibitors ChEBI An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. chebi_ontology anti-AIDS agent anti-AIDS agents anti-HIV agents CHEBI:64946 anti-HIV agent CHEBI:64946 anti-AIDS agent ChEBI anti-AIDS agents ChEBI anti-HIV agents ChEBI A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). Wikipedia:ALOX15 chebi_ontology 15-LOX inhibitor 15-LOX inhibitors 15-lipoxygenase inhibitor 15-lipoxygenase inhibitors EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors EC 1.13.11.33 inhibitor EC 1.13.11.33 inhibitors arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors arachidonate 15-lipoxygenase inhibitor arachidonate 15-lipoxygenase inhibitors arachidonate:oxygen 15-oxidoreductase inhibitor arachidonate:oxygen 15-oxidoreductase inhibitors linoleic acid omega(6)-lipoxygenase inhibitor linoleic acid omega(6)-lipoxygenase inhibitors omega(6) lipoxygenase inhibitor omega(6) lipoxygenase inhibitors CHEBI:64996 EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor CHEBI:64996 15-LOX inhibitor ChEBI 15-LOX inhibitors ChEBI 15-lipoxygenase inhibitor ChEBI 15-lipoxygenase inhibitors ChEBI EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors ChEBI EC 1.13.11.33 inhibitor ChEBI EC 1.13.11.33 inhibitors ChEBI arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor ChEBI arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors ChEBI arachidonate 15-lipoxygenase inhibitor ChEBI arachidonate 15-lipoxygenase inhibitors ChEBI arachidonate:oxygen 15-oxidoreductase inhibitor ChEBI arachidonate:oxygen 15-oxidoreductase inhibitors ChEBI linoleic acid omega(6)-lipoxygenase inhibitor ChEBI linoleic acid omega(6)-lipoxygenase inhibitors ChEBI omega(6) lipoxygenase inhibitor ChEBI omega(6) lipoxygenase inhibitors ChEBI Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). chebi_ontology EC 3.1.1.3 (triacylglycerol lipase) inhibitors EC 3.1.1.3 inhibitor EC 3.1.1.3 inhibitors GEH inhibitor GEH inhibitors PPL inhibitor PPL inhibitors Tween hydrolase inhibitor Tween hydrolase inhibitors Tweenase inhibitor Tweenase inhibitors Tweenesterase inhibitor Tweenesterase inhibitors butyrinase inhibitor butyrinase inhibitors cacordase inhibitor cacordase inhibitors capalase L inhibitor capalase L inhibitors glycerol ester hydrolase inhibitor glycerol ester hydrolase inhibitors glycerol-ester hydrolase inhibitor glycerol-ester hydrolase inhibitors heparin releasable hepatic lipase inhibitor heparin releasable hepatic lipase inhibitors hepatic lipase inhibitor hepatic lipase inhibitors hepatic monoacylglycerol acyltransferase inhibitor hepatic monoacylglycerol acyltransferase inhibitors lipase inhibitor lipase inhibitors lipazin inhibitor lipazin inhibitors liver lipase inhibitor liver lipase inhibitors pancreatic lipase inhibitor pancreatic lipase inhibitors pancreatic triacylglycerol lipase inhibitor pancreatic triacylglycerol lipase inhibitors post-heparin plasma protamine-resistant lipase inhibitor post-heparin plasma protamine-resistant lipase inhibitors salt-resistant post-heparin lipase inhibitor salt-resistant post-heparin lipase inhibitors steapsin inhibitor steapsin inhibitors triacetinase inhibitor triacetinase inhibitors triacylglycerol ester hydrolase inhibitor triacylglycerol ester hydrolase inhibitors triacylglycerol lipase (EC 3.1.1.3) inhibitor triacylglycerol lipase (EC 3.1.1.3) inhibitors triacylglycerol lipase inhibitor triacylglycerol lipase inhibitors tributyrase inhibitor tributyrase inhibitors tributyrin esterase inhibitor tributyrin esterase inhibitors tributyrinase inhibitor tributyrinase inhibitors triglyceridase inhibitor triglyceridase inhibitors triglyceride hydrolase inhibitor triglyceride hydrolase inhibitors triglyceride lipase inhibitor triglyceride lipase inhibitors triolein hydrolase inhibitor triolein hydrolase inhibitors tween-hydrolysing esterase inhibitor tween-hydrolyzing esterase inhibitors CHEBI:65001 EC 3.1.1.3 (triacylglycerol lipase) inhibitor CHEBI:65001 EC 3.1.1.3 (triacylglycerol lipase) inhibitors ChEBI EC 3.1.1.3 inhibitor ChEBI EC 3.1.1.3 inhibitors ChEBI GEH inhibitor ChEBI GEH inhibitors ChEBI PPL inhibitor ChEBI PPL inhibitors ChEBI Tween hydrolase inhibitor ChEBI Tween hydrolase inhibitors ChEBI Tweenase inhibitor ChEBI Tweenase inhibitors ChEBI Tweenesterase inhibitor ChEBI Tweenesterase inhibitors ChEBI butyrinase inhibitor ChEBI butyrinase inhibitors ChEBI cacordase inhibitor ChEBI cacordase inhibitors ChEBI capalase L inhibitor ChEBI capalase L inhibitors ChEBI glycerol ester hydrolase inhibitor ChEBI glycerol ester hydrolase inhibitors ChEBI glycerol-ester hydrolase inhibitor ChEBI glycerol-ester hydrolase inhibitors ChEBI heparin releasable hepatic lipase inhibitor ChEBI heparin releasable hepatic lipase inhibitors ChEBI hepatic lipase inhibitor ChEBI hepatic lipase inhibitors ChEBI hepatic monoacylglycerol acyltransferase inhibitor ChEBI hepatic monoacylglycerol acyltransferase inhibitors ChEBI lipase inhibitor ChEBI lipase inhibitors ChEBI lipazin inhibitor ChEBI lipazin inhibitors ChEBI liver lipase inhibitor ChEBI liver lipase inhibitors ChEBI pancreatic lipase inhibitor ChEBI pancreatic lipase inhibitors ChEBI pancreatic triacylglycerol lipase inhibitor ChEBI pancreatic triacylglycerol lipase inhibitors ChEBI post-heparin plasma protamine-resistant lipase inhibitor ChEBI post-heparin plasma protamine-resistant lipase inhibitors ChEBI salt-resistant post-heparin lipase inhibitor ChEBI salt-resistant post-heparin lipase inhibitors ChEBI steapsin inhibitor ChEBI steapsin inhibitors ChEBI triacetinase inhibitor ChEBI triacetinase inhibitors ChEBI triacylglycerol ester hydrolase inhibitor ChEBI triacylglycerol ester hydrolase inhibitors ChEBI triacylglycerol lipase (EC 3.1.1.3) inhibitor ChEBI triacylglycerol lipase (EC 3.1.1.3) inhibitors ChEBI triacylglycerol lipase inhibitor ChEBI triacylglycerol lipase inhibitors ChEBI tributyrase inhibitor ChEBI tributyrase inhibitors ChEBI tributyrin esterase inhibitor ChEBI tributyrin esterase inhibitors ChEBI tributyrinase inhibitor ChEBI tributyrinase inhibitors ChEBI triglyceridase inhibitor ChEBI triglyceridase inhibitors ChEBI triglyceride hydrolase inhibitor ChEBI triglyceride hydrolase inhibitors ChEBI triglyceride lipase inhibitor ChEBI triglyceride lipase inhibitors ChEBI triolein hydrolase inhibitor ChEBI triolein hydrolase inhibitors ChEBI tween-hydrolysing esterase inhibitor ChEBI tween-hydrolyzing esterase inhibitors ChEBI Any compound that has anti-asthmatic effects. chebi_ontology anti-asthmatic agents antiasthmatic agent antiasthmatic agents CHEBI:65023 anti-asthmatic agent CHEBI:65023 anti-asthmatic agents ChEBI antiasthmatic agent ChEBI antiasthmatic agents ChEBI An organic cation obtained by protonation of the four free amino groups of neamine; major species at pH 7.3. +4 C12H30N4O6 InChI=1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/p+4/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1 SYJXFKPQNSDJLI-HKEUSBCWSA-R 326.38980 326.21434 [NH3+]C[C@H]1O[C@H](O[C@@H]2[C@@H]([NH3+])C[C@@H]([NH3+])[C@H](O)[C@H]2O)[C@H]([NH3+])[C@@H](O)[C@@H]1O PMID:17206729 (1R,2R,3S,4R,6S)-4,6-diazaniumyl-2,3-dihydroxycyclohexyl 2,6-diazaniumyl-2,6-dideoxy-alpha-D-glucopyranoside chebi_ontology neamine neaminium tetracation neaminium(4+) CHEBI:65076 neamine(4+) CHEBI:65076 PMID:17206729 SUBMITTER (1R,2R,3S,4R,6S)-4,6-diazaniumyl-2,3-dihydroxycyclohexyl 2,6-diazaniumyl-2,6-dideoxy-alpha-D-glucopyranoside IUPAC neamine UniProt neaminium tetracation ChEBI neaminium(4+) ChEBI An organic cation obtained by protonation of the six free amino groups of neomycin C; major species at pH 7.3. +6 C23H52N6O13 InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/p+6/t5-,6+,7-,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 PGBHMTALBVVCIT-VZXHOKRSSA-T 620.692 620.35594 [C@H]1([C@H]([C@@H]([C@@H]([NH3+])[C@@H](O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)O[C@H]3[C@@H]([C@H](C[C@H]([C@@H]3O)[NH3+])[NH3+])O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C[NH3+])O)O)[NH3+])O1)O)O)C[NH3+] PMID:17206729 (1R,2R,3S,4R,6S)-4,6-diammmonio-2-{[3-O-(2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranoside chebi_ontology neomycin C CHEBI:65077 neomycin C(6+) CHEBI:65077 PMID:17206729 SUBMITTER (1R,2R,3S,4R,6S)-4,6-diammmonio-2-{[3-O-(2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diammmonio-2,6-dideoxy-alpha-D-glucopyranoside IUPAC neomycin C UniProt A carbohydrate derivative that is any derivative of a polysaccharide. chebi_ontology polysaccharide derivatives CHEBI:65212 polysaccharide derivative CHEBI:65212 polysaccharide derivatives ChEBI Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. chebi_ontology food preservatives CHEBI:65255 food preservative CHEBI:65255 food preservatives ChEBI A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). chebi_ontology antimicrobial food preservatives antimicrobial preservative antimicrobial preservatives CHEBI:65256 antimicrobial food preservative CHEBI:65256 antimicrobial food preservatives ChEBI antimicrobial preservative ChEBI antimicrobial preservatives ChEBI A compound that inhibits the action of gamma-aminobutyric acid. Wikipedia:GABA_antagonist chebi_ontology GABA antagonists gamma-aminobutyric acid receptor antagonist gamma-aminobutyric acid receptor antagonists CHEBI:65259 GABA antagonist CHEBI:65259 GABA antagonists ChEBI gamma-aminobutyric acid receptor antagonist ChEBI gamma-aminobutyric acid receptor antagonists ChEBI An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3. +1 H3NR 17.031 17.02655 [NH3+][*] chebi_ontology a primary amine substituted ammonium CHEBI:65296 primary ammonium ion CHEBI:65296 a primary amine UniProt substituted ammonium ChEBI Any compound that has anti-inflammatory effects. chebi_ontology anti-inflammatory agents antiinflammatory agent antiinflammatory agents CHEBI:67079 anti-inflammatory agent CHEBI:67079 anti-inflammatory agents ChEBI antiinflammatory agent ChEBI antiinflammatory agents ChEBI A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. 0 C17H20N2O6S InChI=1S/C17H20N2O6S/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23)/t11-,12+,15-/m1/s1 RJQXTJLFIWVMTO-TYNCELHUSA-N 380.41500 380.10421 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(OC)cccc1OC)C(O)=O Beilstein:966227 CAS:61-32-5 DrugBank:DB01603 Drug_Central:1744 KEGG:C07177 PMID:11969119 PMID:12569987 PMID:24405901 PMID:24433925 PMID:26962156 Reaxys:966227 Wikipedia:Meticillin 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylic acid Methicillin chebi_ontology (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6beta-(2,6-dimethoxybenzamido)penicillanic acid meticilina meticillin meticilline meticillinum CHEBI:6827 methicillin CHEBI:6827 Beilstein:966227 Beilstein CAS:61-32-5 ChemIDplus CAS:61-32-5 KEGG COMPOUND Drug_Central:1744 DrugCentral PMID:11969119 Europe PMC PMID:12569987 Europe PMC PMID:24405901 Europe PMC PMID:24433925 Europe PMC PMID:26962156 Europe PMC Reaxys:966227 Reaxys 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC Methicillin KEGG_COMPOUND (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC 6beta-(2,6-dimethoxybenzamido)penicillanic acid ChEBI meticilina ChemIDplus meticillin ChemIDplus meticilline ChemIDplus meticillinum ChemIDplus Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. Wikipedia:Azole chebi_ontology azoles CHEBI:68452 azole CHEBI:68452 azoles ChEBI A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer. Wikipedia:MTOR_inhibitors chebi_ontology mTOR inhibitors mammalian target of rapamycin inhibitor mammalian target of rapamycin inhibitors CHEBI:68481 mTOR inhibitor CHEBI:68481 mTOR inhibitors ChEBI mammalian target of rapamycin inhibitor ChEBI mammalian target of rapamycin inhibitors ChEBI Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. chebi_ontology Type I cell-death inducer Type I cell-death inducers Type I programmed cell-death inducer Type I programmed cell-death inducers apoptosis inducers CHEBI:68495 apoptosis inducer CHEBI:68495 Type I cell-death inducer ChEBI Type I cell-death inducers ChEBI Type I programmed cell-death inducer ChEBI Type I programmed cell-death inducers ChEBI apoptosis inducers ChEBI A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. 0 C22H31NO5S InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1 DDVBPZROPPMBLW-IZGXTMSKSA-N 421.55000 421.19229 [H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@H]2C[C@@H](CC[C@H](C)\C=C/C=C/CC\C(C)=C/C(=O)O2)O1 CHEBI:43626 CAS:76343-93-6 PDBeChem:LAR PMID:10859320 PMID:12087066 PMID:17897856 PMID:19528469 PMID:20677927 PMID:22492972 PMID:22498812 PMID:3200109 PMID:3556584 PMID:9250716 Reaxys:4239363 (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one LATRUNCULIN A chebi_ontology (+)-latrunculin A (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one LAT-A LatA NSC 613011 CHEBI:69136 latrunculin A CHEBI:69136 CAS:76343-93-6 ChemIDplus PMID:10859320 Europe PMC PMID:12087066 Europe PMC PMID:17897856 Europe PMC PMID:19528469 Europe PMC PMID:20677927 Europe PMC PMID:22492972 Europe PMC PMID:22498812 Europe PMC PMID:3200109 Europe PMC PMID:3556584 Europe PMC PMID:9250716 Europe PMC Reaxys:4239363 Reaxys (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one IUPAC LATRUNCULIN A PDBeChem (+)-latrunculin A ChEBI (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one PDBeChem LAT-A ChemIDplus LatA ChEBI NSC 613011 ChemIDplus A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. CHEBI:108917 CAS:22916-47-8 DrugBank:DB01110 KEGG:D00416 PMID:11922774 PMID:15187422 PMID:15778703 PMID:16608920 PMID:24389479 PMID:24533891 PMID:24550099 PMID:24629000 PMID:24842191 PMID:24852893 PMID:24919490 PMID:25070654 PMID:25084742 PMID:25179092 PMID:8683405 Reaxys:965511 Wikipedia:Miconazole Miconazole rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole chebi_ontology (+-)-miconazole (RS)-miconazole 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole Daktarin IV Monistat IV (TN) rac-miconazole CHEBI:6923 miconazole CHEBI:6923 CAS:22916-47-8 ChemIDplus CAS:22916-47-8 KEGG DRUG PMID:11922774 Europe PMC PMID:15187422 Europe PMC PMID:15778703 Europe PMC PMID:16608920 Europe PMC PMID:24389479 Europe PMC PMID:24533891 Europe PMC PMID:24550099 Europe PMC PMID:24629000 Europe PMC PMID:24842191 Europe PMC PMID:24852893 Europe PMC PMID:24919490 Europe PMC PMID:25070654 Europe PMC PMID:25084742 Europe PMC PMID:25179092 Europe PMC PMID:8683405 Europe PMC Reaxys:965511 Reaxys Miconazole KEGG_DRUG rac-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole IUPAC (+-)-miconazole ChEBI (RS)-miconazole ChEBI 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole ChemIDplus 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole ChEMBL Daktarin IV ChemIDplus Monistat IV (TN) KEGG_DRUG rac-miconazole ChEBI An alpha,beta-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections. 0 C26H44O9 InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1 MINDHVHHQZYEEK-HBBNESRFSA-N 500.62220 500.29853 C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O CHEBI:44038 CAS:12650-69-0 DrugBank:DB00410 Drug_Central:1857 HMDB:HMDB0014554 KEGG:D01076 PMID:22500807 PMID:23337107 PMID:23535880 PMID:23543635 PMID:24625190 PMID:3101012 Patent:DE2227739 Patent:US3977943 Patent:US4071536 Wikipedia:Mupirocin 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid chebi_ontology Bactroban Centany Pseudomonic acid A mupirocin mupirocina mupirocine mupirocinum CHEBI:7025 mupirocin CHEBI:7025 CAS:12650-69-0 ChemIDplus CAS:12650-69-0 KEGG COMPOUND Drug_Central:1857 DrugCentral PMID:22500807 Europe PMC PMID:23337107 Europe PMC PMID:23535880 Europe PMC PMID:23543635 Europe PMC PMID:24625190 Europe PMC PMID:3101012 Europe PMC 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid IUPAC Bactroban ChemIDplus Centany ChemIDplus Pseudomonic acid A ChemIDplus mupirocin WHO_MedNet mupirocina WHO_MedNet mupirocine WHO_MedNet mupirocinum WHO_MedNet An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). Wikipedia:Topoisomerase chebi_ontology topoisomerase inhibitors CHEBI:70727 topoisomerase inhibitor CHEBI:70727 topoisomerase inhibitors ChEBI Any substance that inhibits the polymerisation of the protein actin. chebi_ontology actin polymerisation inhibitors actin polymerization inhibitor actin polymerization inhibitors inhibitor of actin polymerization inhibitors of actin polymerization CHEBI:70728 actin polymerisation inhibitor CHEBI:70728 actin polymerisation inhibitors ChEBI actin polymerization inhibitor ChEBI actin polymerization inhibitors ChEBI inhibitor of actin polymerization ChEBI inhibitors of actin polymerization ChEBI An organic cation obtained by protonation of the amino groups of any alkane-alpha,omega-diamine; major species at pH 7.3. +2 (CH2)n.C2H10N2 chebi_ontology an alkane-alpha,omega-diamine CHEBI:70977 alkane-alpha,omega-diammonium(2+) CHEBI:70977 an alkane-alpha,omega-diamine UniProt An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2. Wikipedia:Sir2 chebi_ontology Sir2 inhibitors CHEBI:71181 Sir2 inhibitor CHEBI:71181 Sir2 inhibitors ChEBI An organophosphonate oxoanion obtained by deprotonation of both phosphonate OH groups of any phosphonic acid. -2 O3PR 78.972 78.95851 [O-]P([O-])([*])=O chebi_ontology organic phosphonate organophosphonate organophosphonate dianion CHEBI:71285 organophosphonate(2-) CHEBI:71285 organic phosphonate UniProt organophosphonate ChEBI organophosphonate dianion ChEBI An enzyme inhibitor that inhibits the action of a transferase (EC 2.*) Wikipedia:Transferase chebi_ontology EC 2 inhibitor EC 2 inhibitors EC 2.* (transferase) inhibitors EC 2.* inhibitor EC 2.* inhibitors transferase inhibitor transferase inhibitors CHEBI:71300 EC 2.* (transferase) inhibitor CHEBI:71300 EC 2 inhibitor ChEBI EC 2 inhibitors ChEBI EC 2.* (transferase) inhibitors ChEBI EC 2.* inhibitor ChEBI EC 2.* inhibitors ChEBI transferase inhibitor ChEBI transferase inhibitors ChEBI A steroid acid anion that is the conjugate base of fusidic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. -1 C31H47O6 InChI=1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/p-1/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1 IECPWNUMDGFDKC-MZJAQBGESA-M 515.70130 515.33781 [H][C@@]12CC[C@@]3(C)[C@@]([H])([C@H](O)C[C@@]4([H])\C([C@H](C[C@]34C)OC(C)=O)=C(/CCC=C(C)C)C([O-])=O)[C@@]1(C)CC[C@@H](O)[C@H]2C MetaCyc:CPD0-1606 (2Z)-2-[(17Z)-16beta-acetoxy-3alpha,11alpha-dihydroxy-4alpha,8alpha,10,14beta-tetramethyl-5alpha,9beta,13alpha-gonan-17-ylidene]-6-methylhept-5-enoate fusidate chebi_ontology fusidine ramycin CHEBI:71321 fusidate CHEBI:71321 MetaCyc:CPD0-1606 SUBMITTER (2Z)-2-[(17Z)-16beta-acetoxy-3alpha,11alpha-dihydroxy-4alpha,8alpha,10,14beta-tetramethyl-5alpha,9beta,13alpha-gonan-17-ylidene]-6-methylhept-5-enoate IUPAC fusidate UniProt fusidine MetaCyc ramycin MetaCyc An organic anion that is the conjugate base of minocycline, obtained by deprotonation of the two enolic hydroxy groups and protonation of the non-aromatic tertiary amino group. -1 C23H26N3O7 InChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/p-1/t9-,11-,17-,23-/m0/s1 DYKFCLLONBREIL-KVUCHLLUSA-M 456.46840 456.17762 [H][C@@]12Cc3c(ccc(O)c3C(=O)C1=C([O-])[C@]1(O)C(=O)C(C(N)=O)=C([O-])[C@@H]([NH+](C)C)[C@]1([H])C2)N(C)C PMID:20212112 (1S,4aS,11aR,12aS)-3-carbamoyl-10-(dimethylamino)-1-(dimethylazaniumyl)-4a,7-dihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracene-2,5-diolate chebi_ontology minocycline anion CHEBI:71337 minocycline(1-) CHEBI:71337 PMID:20212112 SUBMITTER (1S,4aS,11aR,12aS)-3-carbamoyl-10-(dimethylamino)-1-(dimethylazaniumyl)-4a,7-dihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracene-2,5-diolate IUPAC minocycline anion ChEBI An organic anion that is the conjugate base of novobiocin. -1 C31H35N2O11 InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/p-1/t23-,25+,26-,29-/m1/s1 YJQPYGGHQPGBLI-KGSXXDOSSA-M 611.61640 611.22463 CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c([O-])c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C PMID:20212112 chebi_ontology novobiocin novobiocin anion CHEBI:71339 novobiocin(1-) CHEBI:71339 PMID:20212112 SUBMITTER novobiocin UniProt novobiocin anion ChEBI A zwitterion obtained by transfer of a proton from the 5-hydroxy group to the tertiary amino group of rifampicin; major species at pH 7.3. 0 C43H58N4O12 InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 822.94020 822.40512 CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c([O-])c4c(O)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N1CC[NH+](C)CC1)c(O)c4c3C2=O (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-acetoxy-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-{(E)-[(4-methylpiperazin-4-ium-1-yl)imino]methyl}-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-5-olate chebi_ontology rifampicin CHEBI:71365 rifampicin zwitterion CHEBI:71365 (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-acetoxy-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-{(E)-[(4-methylpiperazin-4-ium-1-yl)imino]methyl}-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-5-olate IUPAC rifampicin UniProt An organic anion that is the conjugate base of tetracycline obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group. -1 C22H23N2O8 InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/p-1/t9-,10-,15-,21+,22-/m0/s1 OFVLGDICTFRJMM-WESIUVDSSA-M 443.42660 443.14599 [H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C([O-])[C@]1(O)C(=O)C(C(N)=O)=C([O-])[C@H]2[NH+](C)C (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,7,11-trihydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracene-2,5-diolate chebi_ontology tetracycline anion CHEBI:71392 tetracycline(1-) CHEBI:71392 (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,7,11-trihydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracene-2,5-diolate IUPAC tetracycline anion ChEBI An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. 0 C8H6N4O5 InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+ NXFQHRVNIOXGAQ-YCRREMRBSA-N 238.157 238.03382 C1(N(/N=C/C=2OC(=CC2)[N+]([O-])=O)CC(N1)=O)=O CHEBI:7591 CAS:67-20-9 DrugBank:DB00698 Drug_Central:1949 KEGG:C07268 KEGG:D00439 PMID:21567157 PMID:22240115 PMID:22252772 PMID:22252808 PMID:22285235 PMID:22332195 PMID:22508296 PMID:22535452 PMID:22552451 PMID:22722224 PMID:22779302 PMID:22787489 PMID:22836745 PMID:22857139 PMID:22869929 PMID:22876623 PMID:22923965 PMID:22929632 PMID:22977056 PMID:23016316 PMID:23109011 PMID:23113731 PMID:23114172 Patent:US2610181 Patent:US2898335 Patent:US2927110 Patent:WO2006019844 Patent:WO2008103673 Patent:WO2010065110 Reaxys:8132135 Wikipedia:Nitrofurantoin 1-{[(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione chebi_ontology 1-((5-Nitrofurfurylidene)amino)hydantoin 1-(5-Nitro-2-furfurylidenamino)hydantoin 1-(5-Nitro-2-furfurylideneamino)hydantoin 1-[(5-Nitrofurfurylidene)amino]hydantoin 5-Nitrofurantoin N-(5-Nitrofurfurylidene)-1-aminohydantoin nitrofurantoin nitrofurantoina nitrofurantoine nitrofurantoinum CHEBI:71415 nitrofurantoin CHEBI:71415 CAS:67-20-9 ChemIDplus CAS:67-20-9 KEGG COMPOUND CAS:67-20-9 NIST Chemistry WebBook Drug_Central:1949 DrugCentral PMID:21567157 Europe PMC PMID:22240115 Europe PMC PMID:22252772 Europe PMC PMID:22252808 Europe PMC PMID:22285235 Europe PMC PMID:22332195 Europe PMC PMID:22508296 Europe PMC PMID:22535452 Europe PMC PMID:22552451 Europe PMC PMID:22722224 Europe PMC PMID:22779302 Europe PMC PMID:22787489 Europe PMC PMID:22836745 Europe PMC PMID:22857139 Europe PMC PMID:22869929 Europe PMC PMID:22876623 Europe PMC PMID:22923965 Europe PMC PMID:22929632 Europe PMC PMID:22977056 Europe PMC PMID:23016316 Europe PMC PMID:23109011 Europe PMC PMID:23113731 Europe PMC PMID:23114172 Europe PMC Reaxys:8132135 Reaxys 1-{[(5-nitro-2-furyl)methylene]amino}imidazolidine-2,4-dione IUPAC 1-((5-Nitrofurfurylidene)amino)hydantoin ChemIDplus 1-(5-Nitro-2-furfurylidenamino)hydantoin ChemIDplus 1-(5-Nitro-2-furfurylideneamino)hydantoin ChemIDplus 1-[(5-Nitrofurfurylidene)amino]hydantoin NIST_Chemistry_WebBook 5-Nitrofurantoin NIST_Chemistry_WebBook N-(5-Nitrofurfurylidene)-1-aminohydantoin ChemIDplus nitrofurantoin KEGG_DRUG nitrofurantoina ChemIDplus nitrofurantoine ChemIDplus nitrofurantoinum ChemIDplus Members of the class of tetrahydrochromenochromene that consists of a cis-fused tetrahydrochromeno[3,4-b]chromene skeleton and its substituted derivatives. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds. Wikipedia:Rotenoids chebi_ontology rotenoids CHEBI:71543 rotenoid CHEBI:71543 rotenoids ChEBI A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life. 0 C143H230N42O37S7 InChI=1S/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27-/t69-,70-,71-,72-,75-,76-,77-,78-,79-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94+,95-,96-,97-,98-,99?,100-,105-,106-,107-,108-,109+,110+,111+,112+/m0/s1 NVNLLIYOARQCIX-IPGQQNLLSA-N 3354.07100 3351.54520 CC[C@H](C)[C@H](N)C(=O)N\C(=C/C)C(=O)N[C@@H]1CSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H](NC1=O)[C@@H](C)CC)C(=O)N[C@@H]1[C@H](C)SC[C@H](NC(=O)CNC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1[C@H](C)SC[C@H](NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]1[C@H](C)SCC2NC(=O)[C@H](NC(=O)[C@H](C)NC1=O)[C@H](C)SC[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)NC(=C)C(=O)N[C@@H](CCCCN)C(O)=O CAS:1414-45-5 PMID:16247668 PMID:21294231 PMID:22265294 PMID:22691226 PMID:22850391 Patent:US2935503 Reaxys:8188142 Wikipedia:Nisin N-{[(1S,4S,7S,8S,11R,14S,17R,20S)-7-{[N(2)-({(3R,9S,12S,15S,21S,22S)-21-[(N(2)-{[(6R,9S,10S,15aS)-10-({[(3R,6S,12S,15S)-12-[(2S)-butan-2-yl]-6-isobutyl-15-{[(2Z)-2-(L-isoleucylamino)but-2-enoyl]amino}-9-methylene-5,8,11,14-tetraoxo-1-thia-4,7,10,13-tetraazacyclohexadecan-3-yl]carbonyl}amino)-9-methyl-1,4,11-trioxododecahydro-1H,9H-pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecin-6-yl]carbonyl}-L-lysyl)amino]-12-isobutyl-15,22-dimethyl-9-[2-(methylsulfanyl)ethyl]-5,8,11,14,17,20-hexaoxo-1-thia-4,7,10,13,16,19-hexaazacyclodocosan-3-yl}carbonyl)-L-asparaginyl-L-methionyl-L-lysyl]amino}-14-(1H-imidazol-5-ylmethyl)-4,8,20-trimethyl-3,6,12,15,21-pentaoxo-9,19-dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docos-17-yl]carbonyl}-L-seryl-L-isoleucyl-L-histidyl-N-(3-{[(1S)-5-amino-1-carboxypentyl]amino}-3-oxoprop-1-en-2-yl)-L-valinamide chebi_ontology E234 EINECS 215-807-5 NSC 112903 NSC-112903 CHEBI:71629 nisin CHEBI:71629 CAS:1414-45-5 ChemIDplus PMID:16247668 Europe PMC PMID:21294231 Europe PMC PMID:22265294 Europe PMC PMID:22691226 Europe PMC PMID:22850391 Europe PMC Reaxys:8188142 Reaxys N-{[(1S,4S,7S,8S,11R,14S,17R,20S)-7-{[N(2)-({(3R,9S,12S,15S,21S,22S)-21-[(N(2)-{[(6R,9S,10S,15aS)-10-({[(3R,6S,12S,15S)-12-[(2S)-butan-2-yl]-6-isobutyl-15-{[(2Z)-2-(L-isoleucylamino)but-2-enoyl]amino}-9-methylene-5,8,11,14-tetraoxo-1-thia-4,7,10,13-tetraazacyclohexadecan-3-yl]carbonyl}amino)-9-methyl-1,4,11-trioxododecahydro-1H,9H-pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecin-6-yl]carbonyl}-L-lysyl)amino]-12-isobutyl-15,22-dimethyl-9-[2-(methylsulfanyl)ethyl]-5,8,11,14,17,20-hexaoxo-1-thia-4,7,10,13,16,19-hexaazacyclodocosan-3-yl}carbonyl)-L-asparaginyl-L-methionyl-L-lysyl]amino}-14-(1H-imidazol-5-ylmethyl)-4,8,20-trimethyl-3,6,12,15,21-pentaoxo-9,19-dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docos-17-yl]carbonyl}-L-seryl-L-isoleucyl-L-histidyl-N-(3-{[(1S)-5-amino-1-carboxypentyl]amino}-3-oxoprop-1-en-2-yl)-L-valinamide IUPAC E234 ChEBI EINECS 215-807-5 ChemIDplus NSC 112903 ChemIDplus NSC-112903 ChemIDplus A class of peptide antibiotic characterised by the presence of the rare thioether amino acids lanthionine or methyllanthionine, as well as the unsaturated amino acids dehydroalanine and 2-aminoisobutyric acid. In contrast to classical peptide antibiotics, lantibiotics are synthesised from precursor genes using the ribosomal pathway and the characteristic rare amino acids are introduced by posttranslational modification procedues into the lantibiotic precursor peptides ('prepeptides'). Lantibiotics are subdivided into two types: type A have long, flexible structures, while type B have rigid, globular structures. PMID:10584332 PMID:10826980 PMID:10931442 PMID:11348686 PMID:12369187 PMID:15700960 PMID:16917798 PMID:17506681 PMID:18220976 PMID:19149587 PMID:19275538 PMID:19393544 PMID:21464591 PMID:21960309 PMID:22329892 PMID:8264800 PMID:8688628 PMID:8775975 PMID:9891793 Wikipedia:Lantibiotics chebi_ontology lantibiotics CHEBI:71644 lantibiotic CHEBI:71644 PMID:10584332 Europe PMC PMID:10826980 Europe PMC PMID:10931442 Europe PMC PMID:11348686 Europe PMC PMID:12369187 Europe PMC PMID:15700960 Europe PMC PMID:16917798 Europe PMC PMID:17506681 Europe PMC PMID:18220976 Europe PMC PMID:19149587 Europe PMC PMID:19275538 Europe PMC PMID:19393544 Europe PMC PMID:21464591 Europe PMC PMID:21960309 Europe PMC PMID:22329892 Europe PMC PMID:8264800 Europe PMC PMID:8688628 Europe PMC PMID:8775975 Europe PMC PMID:9891793 Europe PMC lantibiotics ChEBI Any lantibiotic which has which has a long, flexible structure. PMID:18848642 PMID:21517737 chebi_ontology type 1 lantibiotic type 1 lantibiotics type A lantibiotics type-A lantibiotic type-A lantibiotics CHEBI:71645 type A lantibiotic CHEBI:71645 PMID:18848642 Europe PMC PMID:21517737 Europe PMC type 1 lantibiotic ChEBI type 1 lantibiotics ChEBI type A lantibiotics ChEBI type-A lantibiotic ChEBI type-A lantibiotics ChEBI Any organooxygen compound that has the general formula RC(OR(1))(OR(2))(OR(3)), where R(1), R(2), R(3) =/= H. 0 CO3R4 60.00890 59.98474 [*]C(O[*])(O[*])O[*] Wikipedia:Orthoester chebi_ontology ortho esters ortho-ester ortho-esters orthoester orthoesters CHEBI:71989 ortho ester CHEBI:71989 ortho esters ChEBI ortho-ester ChEBI ortho-esters ChEBI orthoester ChEBI orthoesters ChEBI Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host. PMID:22851449 Wikipedia:Virulence_factor chebi_ontology virulence factors CHEBI:72316 virulence factor CHEBI:72316 PMID:22851449 Europe PMC virulence factors ChEBI Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them. Wikipedia:Flavonoids chebi_ontology flavonoid CHEBI:72544 flavonoids CHEBI:72544 flavonoid ChEBI Any chromenochromene resulting from the formal cis-fusion of two dihydro chromene rings, together with their substituted derivatives. chebi_ontology tetrahydrochromenochromenes CHEBI:72579 tetrahydrochromenochromene CHEBI:72579 tetrahydrochromenochromenes ChEBI Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton and its substituted products. 0 C16O3R12 240.16940 239.98474 [*]c1c([*])c([*])c2C(=O)C3([*])c4c([*])c([*])c([*])c([*])c4OC([*])([*])C3([*])Oc2c1[*] chebi_ontology CHEBI:72581 rotenones CHEBI:72581 Any organic molecular entity derived from a natural product by partial chemical synthesis. Wikipedia:Semisynthesis chebi_ontology semi-synthetic compound semi-synthetic compounds semi-synthetic derivative semi-synthetic derivatives semisynthetic compound semisynthetic compounds semisynthetic derivatives CHEBI:72588 semisynthetic derivative CHEBI:72588 semi-synthetic compound ChEBI semi-synthetic compounds ChEBI semi-synthetic derivative ChEBI semi-synthetic derivatives ChEBI semisynthetic compound ChEBI semisynthetic compounds ChEBI semisynthetic derivatives ChEBI A cyclic ketal in which the ketal carbon is the only common atom of two rings. PMID:19262920 PMID:20024126 PMID:21076755 PMID:21604735 PMID:21860857 PMID:22421755 chebi_ontology spiroacetal spiroacetals spiroketals CHEBI:72600 spiroketal CHEBI:72600 PMID:19262920 Europe PMC PMID:20024126 Europe PMC PMID:21076755 Europe PMC PMID:21604735 Europe PMC PMID:21860857 Europe PMC PMID:22421755 Europe PMC spiroacetal ChEBI spiroacetals ChEBI spiroketals ChEBI Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. chebi_ontology organic compound organic compounds organic molecules CHEBI:72695 organic molecule CHEBI:72695 organic compound ChEBI organic compounds ChEBI organic molecules ChEBI An agonist that binds to and activates aryl hydrocarbon receptors (AhRs). chebi_ontology AHR agonist AHR agonists AhR agonist AhR agonists aryl hydrocarbon receptor agonists CHEBI:72768 aryl hydrocarbon receptor agonist CHEBI:72768 AHR agonist ChEBI AHR agonists ChEBI AhR agonist ChEBI AhR agonists ChEBI aryl hydrocarbon receptor agonists ChEBI Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable. 0 CHNOR4 43.025 43.00581 OC([*])([*])N([*])[*] Wikipedia:Hemiaminal chebi_ontology carbinolamine carbinolamines hemiaminals CHEBI:73080 hemiaminal CHEBI:73080 carbinolamine ChEBI carbinolamines ChEBI hemiaminals ChEBI An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11). Wikipedia:L-ascorbate_peroxidase chebi_ontology EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors EC 1.11.1.11 inhibitor EC 1.11.1.11 inhibitors L-ascorbate peroxidase (EC 1.11.1.11) inhibitor L-ascorbate peroxidase (EC 1.11.1.11) inhibitors L-ascorbate peroxidase inhibitor L-ascorbate peroxidase inhibitors L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors L-ascorbic acid peroxidase inhibitor L-ascorbic acid peroxidase inhibitors L-ascorbic acid-specific peroxidase inhibitor L-ascorbic acid-specific peroxidase inhibitors ascorbate peroxidase inhibitor ascorbate peroxidase inhibitors ascorbic acid peroxidase inhibitor ascorbic acid peroxidase inhibitors CHEBI:73181 EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor CHEBI:73181 EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors ChEBI EC 1.11.1.11 inhibitor ChEBI EC 1.11.1.11 inhibitors ChEBI L-ascorbate peroxidase (EC 1.11.1.11) inhibitor ChEBI L-ascorbate peroxidase (EC 1.11.1.11) inhibitors ChEBI L-ascorbate peroxidase inhibitor ChEBI L-ascorbate peroxidase inhibitors ChEBI L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor ChEBI L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors ChEBI L-ascorbic acid peroxidase inhibitor ChEBI L-ascorbic acid peroxidase inhibitors ChEBI L-ascorbic acid-specific peroxidase inhibitor ChEBI L-ascorbic acid-specific peroxidase inhibitors ChEBI ascorbate peroxidase inhibitor ChEBI ascorbate peroxidase inhibitors ChEBI ascorbic acid peroxidase inhibitor ChEBI ascorbic acid peroxidase inhibitors ChEBI Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*). CHEBI:76765 chebi_ontology EC 3.6 inhibitor EC 3.6 inhibitors EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors EC 3.6.* inhibitor EC 3.6.* inhibitors EC 3.6.*.* inhibitor EC 3.6.*.* inhibitors acid anhydride hydrolase inhibitor acid anhydride hydrolase inhibitors inhibitor of hydrolase acting on acid anhydride (EC 3.6.*) inhibitors of hydrolase acting on acid anhydride (EC 3.6.*) CHEBI:73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor CHEBI:73216 EC 3.6 inhibitor ChEBI EC 3.6 inhibitors ChEBI EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors ChEBI EC 3.6.* inhibitor ChEBI EC 3.6.* inhibitors ChEBI EC 3.6.*.* inhibitor ChEBI EC 3.6.*.* inhibitors ChEBI acid anhydride hydrolase inhibitor ChEBI acid anhydride hydrolase inhibitors ChEBI inhibitor of hydrolase acting on acid anhydride (EC 3.6.*) ChEBI inhibitors of hydrolase acting on acid anhydride (EC 3.6.*) ChEBI A drug used in treating and healing of wounds. Wikipedia:Wound_healing chebi_ontology vulneraries wound-healing agent wound-healing agents wound-healing drug wound-healing drugs CHEBI:73336 vulnerary CHEBI:73336 vulneraries ChEBI wound-healing agent ChEBI wound-healing agents ChEBI wound-healing drug ChEBI wound-healing drugs ChEBI Any organic molecule containing a C#C bond. 0 C2R2 24.021 24.00000 [*]C#C[*] chebi_ontology C#C containing compound C#C containing compounds C#C-containing compound C#C-containing compounds acetylenic compounds CHEBI:73474 acetylenic compound CHEBI:73474 C#C containing compound ChEBI C#C containing compounds ChEBI C#C-containing compound ChEBI C#C-containing compounds ChEBI acetylenic compounds ChEBI Any naphthyridine derivative that is a derivative of 1,8-naphthyridine. chebi_ontology 1,8-naphthyridine derivatives CHEBI:73537 1,8-naphthyridine derivative CHEBI:73537 1,8-naphthyridine derivatives ChEBI Any organonitrogen heterocyclic compound that is a derivative of a naphthyridine. chebi_ontology naphthyridine derivatives CHEBI:73539 naphthyridine derivative CHEBI:73539 naphthyridine derivatives ChEBI An organic cation obtained by protonation of the five amino groups of tobramycin. +5 C18H42N5O9 InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/p+5/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 NLVFBUXFDBBNBW-PBSUHMDJSA-S 472.55420 472.29551 [NH3+]C[C@H]1O[C@H](O[C@@H]2[C@@H]([NH3+])C[C@@H]([NH3+])[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H]([NH3+])[C@H]3O)[C@H]2O)[C@H]([NH3+])C[C@@H]1O PMID:22383337 (1S,2S,3R,4S,6R)-4,6-diazaniumyl-3-[(2,6-diazaniumyl-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside chebi_ontology tobramycin CHEBI:73678 tobramycin(5+) CHEBI:73678 PMID:22383337 SUBMITTER (1S,2S,3R,4S,6R)-4,6-diazaniumyl-3-[(2,6-diazaniumyl-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside IUPAC tobramycin UniProt A carbohydrate derivative in which one or more of the oxygens or hydroxy groups of the parent carbohydrate is replaced by sulfur or -SR, where R can be hydrogen or any group. PMID:16240117 PMID:23330717 chebi_ontology thiosugars CHEBI:73754 thiosugar CHEBI:73754 PMID:16240117 Europe PMC PMID:23330717 Europe PMC thiosugars ChEBI An antimetabolite that impairs the action of folic acids Wikipedia:Antifolate chebi_ontology antifolates folic acid antagonist folic acid antagonists CHEBI:73913 antifolate CHEBI:73913 antifolates ChEBI folic acid antagonist ChEBI folic acid antagonists ChEBI A zwitterion resulting from the transfer of a proton from the ring nitrogen to the primary amino group of D-cycloserine. The major species at pH 7.3. 0 C3H6N2O2 InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1 DYDCUQKUCUHJBH-UWTATZPHSA-N 102.09190 102.04293 [H][C@@]1([NH3+])CO[N-]C1=O MetaCyc:CPD-2482 PMID:20086163 PMID:23529730 (4R)-4-ammonio-3-oxo-1,2-oxazolidin-2-ide chebi_ontology (+)-4-amino-3-isoxazolidinone zwitterion (4R)-4-aminoisoxazolidin-3-one zwitterion D-4-amino-3-isoxazolidinone zwitterion alpha-cycloserine zwitterion cycloserine zwitterion CHEBI:74159 D-cycloserine zwitterion CHEBI:74159 MetaCyc:CPD-2482 SUBMITTER PMID:20086163 SUBMITTER PMID:23529730 SUBMITTER (4R)-4-ammonio-3-oxo-1,2-oxazolidin-2-ide IUPAC (+)-4-amino-3-isoxazolidinone zwitterion ChEBI (4R)-4-aminoisoxazolidin-3-one zwitterion ChEBI D-4-amino-3-isoxazolidinone zwitterion ChEBI alpha-cycloserine zwitterion ChEBI cycloserine zwitterion ChEBI A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections. 0 C21H21N InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+ OZGNYLLQHRPOBR-DHZHZOJOSA-N 287.39810 287.16740 CN(C\C=C\c1ccccc1)Cc1cccc2ccccc12 CAS:65472-88-0 DrugBank:DB00735 Drug_Central:1872 HMDB:HMDB0014873 KEGG:C08071 KEGG:D08245 PMID:18212112 PMID:24196340 PMID:25294700 PMID:6388170 Patent:BE853976 Patent:US4282251 Reaxys:2983617 Wikipedia:Naftifine (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine chebi_ontology (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine naftifin naftifina naftifine naftifinum trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine CHEBI:7451 naftifine CHEBI:7451 CAS:65472-88-0 ChemIDplus CAS:65472-88-0 KEGG COMPOUND Drug_Central:1872 DrugCentral PMID:18212112 Europe PMC PMID:24196340 Europe PMC PMID:25294700 Europe PMC PMID:6388170 Europe PMC Reaxys:2983617 Reaxys (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine IUPAC (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine ChemIDplus naftifin ChemIDplus naftifina WHO_MedNet naftifine KEGG_DRUG naftifine WHO_MedNet naftifinum WHO_MedNet trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine ChEBI A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. Wikipedia:Astringent chebi_ontology adstringent adstringents astringents CHEBI:74783 astringent CHEBI:74783 adstringent ChEBI adstringents ChEBI astringents ChEBI Any organic aromatic compound having one or more hydroxy groups attached to a heteroarene ring. chebi_ontology hetaryl hydroxy compound hetaryl hydroxy compounds heteroaromatic hydroxy compound heteroaromatic hydroxy compounds heteroaryl hydroxy compounds CHEBI:74818 heteroaryl hydroxy compound CHEBI:74818 hetaryl hydroxy compound ChEBI hetaryl hydroxy compounds ChEBI heteroaromatic hydroxy compound ChEBI heteroaromatic hydroxy compounds ChEBI heteroaryl hydroxy compounds ChEBI 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group. 0 C12H26N4O6 InChI=1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1 SYJXFKPQNSDJLI-HKEUSBCWSA-N 322.35800 322.18523 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O CHEBI:46591 CHEBI:481318 CAS:3947-65-7 DrugBank:DB04808 KEGG:C01441 PDBeChem:XXX PMID:1008820 PMID:16361562 PMID:16870442 PMID:16942021 PMID:17317190 PMID:17416529 PMID:19276260 PMID:20000576 PMID:21135992 Reaxys:26714 (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside Neamine neamine chebi_ontology 2-desoxy-4-O-(2,6-diamino-2,6-didesoxy-alpha-D-glucopyranosyl)-D-streptamin 4-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-2-deoxy-D-streptamine Neomycin A CHEBI:7489 neamine CHEBI:7489 CAS:3947-65-7 ChemIDplus CAS:3947-65-7 KEGG COMPOUND PMID:1008820 Europe PMC PMID:16361562 Europe PMC PMID:16870442 ChEMBL PMID:16942021 ChEMBL PMID:17317190 ChEMBL PMID:17416529 ChEMBL PMID:19276260 Europe PMC PMID:20000576 Europe PMC PMID:21135992 Europe PMC Reaxys:26714 Reaxys (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside IUPAC Neamine KEGG_COMPOUND neamine ChEMBL 2-desoxy-4-O-(2,6-diamino-2,6-didesoxy-alpha-D-glucopyranosyl)-D-streptamin ChemIDplus 4-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-2-deoxy-D-streptamine ChemIDplus Neomycin A KEGG_COMPOUND A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections. CAS:1404-04-2 DrugBank:DB00994 KEGG:C00384 KEGG:D08260 Neomycin chebi_ontology CHEBI:7507 neomycin CHEBI:7507 CAS:1404-04-2 KEGG COMPOUND Neomycin KEGG_COMPOUND A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. 0 C23H46N6O13 InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 PGBHMTALBVVCIT-VCIWKGPPSA-N 614.64370 614.31229 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O CHEBI:44577 Beilstein:101621 CAS:119-04-0 DrugBank:DB00452 Drug_Central:1896 KEGG:C01737 KEGG:D05140 LINCS:LSM-5787 MetaCyc:CPD-14142 PDBeChem:NMY PMID:25129497 PMID:25230155 PMID:25450807 PMID:25588492 PMID:8548964 Reaxys:101621 VSDB:1783 (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside Framycetin chebi_ontology Fradiomycin B Neomycin B framicetina framycetine framycetinum CHEBI:7508 framycetin CHEBI:7508 Beilstein:101621 Beilstein CAS:119-04-0 ChemIDplus CAS:119-04-0 KEGG COMPOUND Drug_Central:1896 DrugCentral PMID:25129497 Europe PMC PMID:25230155 Europe PMC PMID:25450807 Europe PMC PMID:25588492 Europe PMC PMID:8548964 Europe PMC Reaxys:101621 Reaxys (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside IUPAC Framycetin ChemIDplus Framycetin KEGG_COMPOUND Fradiomycin B KEGG_COMPOUND Neomycin B KEGG_COMPOUND framicetina ChemIDplus framycetine ChemIDplus framycetinum ChemIDplus 0 C21H41N5O7 InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)15(28)17(13)33-20-21(2,29)18(25-3)14(27)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15+,16-,17+,18-,19-,20-,21-/m1/s1 ZBGPYVZLYBDXKO-HILBYHGXSA-N 475.57974 475.30060 CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@H](O)[C@@H](NC)[C@@]1(C)O CAS:56391-56-1 DrugBank:DB00955 KEGG:C07657 KEGG:D08268 (1S,2S,3R,4S,6R)-4-amino-3-[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yloxy]-6-(ethylamino)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside chebi_ontology 1-N-Ethylsisomicin Netilmicin O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-N(1)-ethyl-D-streptamine CHEBI:7528 netilmycin CHEBI:7528 CAS:56391-56-1 ChemIDplus CAS:56391-56-1 KEGG COMPOUND (1S,2S,3R,4S,6R)-4-amino-3-[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yloxy]-6-(ethylamino)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside IUPAC 1-N-Ethylsisomicin ChemIDplus Netilmicin KEGG_COMPOUND O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-N(1)-ethyl-D-streptamine ChemIDplus Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. PMID:12604527 PMID:19835945 chebi_ontology ergosterol biosynthesis inhibitors CHEBI:75282 ergosterol biosynthesis inhibitor CHEBI:75282 PMID:12604527 Europe PMC PMID:19835945 Europe PMC ergosterol biosynthesis inhibitors ChEBI A phospholipid that is the hexadecyl monoester of phosphocholine. 0 C21H46NO4P InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3 PQLXHQMOHUQAKB-UHFFFAOYSA-N 407.56800 407.31645 CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C CAS:58066-85-6 Drug_Central:1810 KEGG:D02494 PMID:22385017 PMID:22935677 PMID:22995097 PMID:23136856 PMID:23165465 PMID:23199340 PMID:23239091 PMID:23243111 PMID:23434530 PMID:23434716 PMID:23468121 PMID:23601234 PMID:23673723 PMID:23723490 PMID:23729024 PMID:23738749 PMID:23740007 PMID:23811261 PMID:23811637 PMID:23861311 PMID:23871798 PMID:23890327 PMID:23930349 Reaxys:3690495 Wikipedia:Miltefosine chebi_ontology Hexadecylphosphocholine Hexadecylphosphorylcholine miltefosina miltefosine miltefosinum monohexadecylphosphocholine monohexadecylphosphorylcholine CHEBI:75283 miltefosine CHEBI:75283 CAS:58066-85-6 ChemIDplus CAS:58066-85-6 KEGG DRUG Drug_Central:1810 DrugCentral PMID:22385017 Europe PMC PMID:22935677 Europe PMC PMID:22995097 Europe PMC PMID:23136856 Europe PMC PMID:23165465 Europe PMC PMID:23199340 Europe PMC PMID:23239091 Europe PMC PMID:23243111 Europe PMC PMID:23434530 Europe PMC PMID:23434716 Europe PMC PMID:23468121 Europe PMC PMID:23601234 Europe PMC PMID:23673723 Europe PMC PMID:23723490 Europe PMC PMID:23729024 Europe PMC PMID:23738749 Europe PMC PMID:23740007 Europe PMC PMID:23811261 Europe PMC PMID:23811637 Europe PMC PMID:23861311 Europe PMC PMID:23871798 Europe PMC PMID:23890327 Europe PMC PMID:23930349 Europe PMC Reaxys:3690495 Reaxys Hexadecylphosphocholine ChemIDplus Hexadecylphosphorylcholine ChemIDplus miltefosina ChemIDplus miltefosine KEGG_DRUG miltefosine WHO_MedNet miltefosinum ChemIDplus monohexadecylphosphocholine ChEBI monohexadecylphosphorylcholine ChEBI An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*). Wikipedia:Peroxidases chebi_ontology EC 1.11.1 inhibitor EC 1.11.1 inhibitors EC 1.11.1.* (peroxidase) inhibitor EC 1.11.1.* (peroxidase) inhibitors EC 1.11.1.* (peroxidases) inhibitors EC 1.11.1.* inhibitor EC 1.11.1.* inhibitors inhibitor of peroxidases inhibitors of peroxidases peroxidases inhibitors CHEBI:75381 EC 1.11.1.* (peroxidases) inhibitor CHEBI:75381 EC 1.11.1 inhibitor ChEBI EC 1.11.1 inhibitors ChEBI EC 1.11.1.* (peroxidase) inhibitor ChEBI EC 1.11.1.* (peroxidase) inhibitors ChEBI EC 1.11.1.* (peroxidases) inhibitors ChEBI EC 1.11.1.* inhibitor ChEBI EC 1.11.1.* inhibitors ChEBI inhibitor of peroxidases ChEBI inhibitors of peroxidases ChEBI peroxidases inhibitors ChEBI A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora. 0 C3H6N2O2 InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1 DYDCUQKUCUHJBH-REOHCLBHSA-N 102.09190 102.04293 [H][C@]1(N)CONC1=O CAS:339-72-0 DrugBank:DB00260 HMDB:HMDB0014405 KEGG:D04706 LINCS:LSM-5639 MetaCyc:CPD-2483 PMID:19932170 PMID:3430071 PMID:3771514 PMID:4150977 PMID:638858 PMID:6501090 PMID:6723595 PMID:7353584 PMID:8556395 Reaxys:80799 (4S)-4-amino-1,2-oxazolidin-3-one chebi_ontology (-)-4-amino-3-isoxazolidinone (-)-4-aminoisoxazolidin-3-one (-)-cycloserine (4S)-4-aminoisoxazolidin-3-one (S)-(-)-cycloserine (S)-4-amino-3-isoxazolidinone (S)-4-amino-isoxazolidin-3-one L-4-aminoisoxazolidin-3-one L-CS cyclo-L-serine levcicloserina levcycloserine levcycloserinum CHEBI:75592 L-cycloserine CHEBI:75592 CAS:339-72-0 ChemIDplus PMID:19932170 Europe PMC PMID:3430071 Europe PMC PMID:3771514 Europe PMC PMID:4150977 Europe PMC PMID:638858 Europe PMC PMID:6501090 Europe PMC PMID:6723595 Europe PMC PMID:7353584 Europe PMC PMID:8556395 Europe PMC Reaxys:80799 Reaxys (4S)-4-amino-1,2-oxazolidin-3-one IUPAC (-)-4-amino-3-isoxazolidinone ChemIDplus (-)-4-aminoisoxazolidin-3-one ChEBI (-)-cycloserine ChEBI (4S)-4-aminoisoxazolidin-3-one IUPAC (S)-(-)-cycloserine ChemIDplus (S)-4-amino-3-isoxazolidinone ChemIDplus (S)-4-amino-isoxazolidin-3-one ChEBI L-4-aminoisoxazolidin-3-one ChEBI L-CS ChEBI cyclo-L-serine ChemIDplus levcicloserina ChemIDplus levcycloserine ChemIDplus levcycloserine WHO_MedNet levcycloserinum ChemIDplus An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). chebi_ontology EC 5.* (isomerase) inhibitors EC 5.* inhibitor EC 5.* inhibitors EC 5.*.*.* inhibitor EC 5.*.*.* inhibitors isomerase (EC 5.*) inhibitor isomerase (EC 5.*) inhibitors isomerase inhibitor isomerase inhibitors CHEBI:75596 EC 5.* (isomerase) inhibitor CHEBI:75596 EC 5.* (isomerase) inhibitors ChEBI EC 5.* inhibitor ChEBI EC 5.* inhibitors ChEBI EC 5.*.*.* inhibitor ChEBI EC 5.*.*.* inhibitors ChEBI isomerase (EC 5.*) inhibitor ChEBI isomerase (EC 5.*) inhibitors ChEBI isomerase inhibitor ChEBI isomerase inhibitors ChEBI A carboxamide that is a hydroxamic acid in which the hydrogen of the hydroxy group is replaced by an organyl group. 0 CHNO2R2 59.02410 59.00073 [*]C(=O)NO[*] chebi_ontology RC(O)NHOR' RCONHOR' hydroxamate ester hydroxamate esters hydroxamic acid esters CHEBI:75606 hydroxamic acid ester CHEBI:75606 RC(O)NHOR' ChEBI RCONHOR' ChEBI hydroxamate ester ChEBI hydroxamate esters ChEBI hydroxamic acid esters ChEBI An organic cation obtained by protonation of the five amino groups of any gentamicin C. +5 C19H42N5O7R2 452.567 452.30842 C[NH2+][C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H]([NH3+])C[C@H]([NH3+])[C@@H](O[C@H]3O[C@@H](CC[C@H]3[NH3+])[C@@H]([*])[NH2+][*])[C@@H]2O)OC[C@]1(C)O chebi_ontology gentamicin C CHEBI:75616 gentamicin C(5+) CHEBI:75616 gentamicin C UniProt 0 C10H13N3O5S InChI=1S/C10H13N3O5S/c1-8-7-19(16,17)5-4-12(8)11-6-9-2-3-10(18-9)13(14)15/h2-3,6,8H,4-5,7H2,1H3/b11-6+ ARFHIAQFJWUCFH-IZZDOVSWSA-N 287.294 287.05759 CC1CS(=O)(=O)CCN1\N=C\c1ccc(o1)[N+]([O-])=O CAS:23256-30-6 Drug_Central:1929 KEGG:C08002 KEGG:D00833 Nifurtimox chebi_ontology Bayer 2502 lampit CHEBI:7566 Nifurtimox CHEBI:7566 CAS:23256-30-6 KEGG COMPOUND Drug_Central:1929 DrugCentral Nifurtimox KEGG_COMPOUND Bayer 2502 DrugCentral lampit DrugCentral Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. chebi_ontology eukaryotic metabolites CHEBI:75763 eukaryotic metabolite CHEBI:75763 eukaryotic metabolites ChEBI Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. CHEBI:77721 CHEBI:77743 chebi_ontology animal metabolites CHEBI:75767 animal metabolite CHEBI:75767 animal metabolites ChEBI Any animal metabolite produced during a metabolic reaction in mammals. CHEBI:77464 CHEBI:77744 chebi_ontology mammalian metabolites CHEBI:75768 mammalian metabolite CHEBI:75768 mammalian metabolites ChEBI Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such). MetaCyc:B-vitamins PMID:22743781 PMID:23093174 PMID:23238962 PMID:23449527 PMID:23462586 PMID:23690582 Wikipedia:B_vitamin chebi_ontology B vitamins B-group vitamin B-group vitamins vitamin B CHEBI:75769 B vitamin CHEBI:75769 PMID:22743781 Europe PMC PMID:23093174 Europe PMC PMID:23238962 Europe PMC PMID:23449527 Europe PMC PMID:23462586 Europe PMC PMID:23690582 Europe PMC B vitamins ChEBI B-group vitamin ChEBI B-group vitamins ChEBI vitamin B ChEBI Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). chebi_ontology Mus musculus metabolite Mus musculus metabolites mouse metabolites CHEBI:75771 mouse metabolite CHEBI:75771 Mus musculus metabolite ChEBI Mus musculus metabolites ChEBI mouse metabolites ChEBI Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae). CHEBI:76949 CHEBI:76951 chebi_ontology S. cerevisiae metabolite S. cerevisiae metabolites S. cerevisiae secondary metabolite S. cerevisiae secondary metabolites Saccharomyces cerevisiae metabolites Saccharomyces cerevisiae secondary metabolites baker's yeast metabolite baker's yeast metabolites baker's yeast secondary metabolite baker's yeast secondary metabolites CHEBI:75772 Saccharomyces cerevisiae metabolite CHEBI:75772 S. cerevisiae metabolite ChEBI S. cerevisiae metabolites ChEBI S. cerevisiae secondary metabolite ChEBI S. cerevisiae secondary metabolites ChEBI Saccharomyces cerevisiae metabolites ChEBI Saccharomyces cerevisiae secondary metabolites ChEBI baker's yeast metabolite ChEBI baker's yeast metabolites ChEBI baker's yeast secondary metabolite ChEBI baker's yeast secondary metabolites ChEBI Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. chebi_ontology prokaryotic metabolites CHEBI:75787 prokaryotic metabolite CHEBI:75787 prokaryotic metabolites ChEBI An organic cation that is the conjugate acid of D-cycloserine, obtained by protonation of the amino group. +1 C3H7N2O2 InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/p+1/t2-/m1/s1 DYDCUQKUCUHJBH-UWTATZPHSA-O 103.09990 103.05020 [NH3+][C@@H]1CONC1=O (4R)-3-oxo-1,2-oxazolidin-4-aminium chebi_ontology D-cycloserine CHEBI:75929 D-cycloserine(1+) CHEBI:75929 (4R)-3-oxo-1,2-oxazolidin-4-aminium IUPAC D-cycloserine UniProt A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino group of vancomycin aglycone. 0 C53H52Cl2N8O17 InChI=1S/C53H52Cl2N8O17/c1-19(2)10-29(57-3)47(71)62-42-44(68)21-5-8-33(27(54)12-21)79-35-14-23-15-36(46(35)70)80-34-9-6-22(13-28(34)55)45(69)43-52(76)61-41(53(77)78)26-16-24(64)17-32(66)38(26)25-11-20(4-7-31(25)65)39(49(73)63-43)60-50(74)40(23)59-48(72)30(18-37(56)67)58-51(42)75/h4-9,11-17,19,29-30,39-45,57,64-66,68-70H,10,18H2,1-3H3,(H2,56,67)(H,58,75)(H,59,72)(H,60,74)(H,61,76)(H,62,71)(H,63,73)(H,77,78)/t29-,30+,39-,40-,41+,42-,43+,44-,45-/m1/s1 JHIKFOISFAQTJQ-YZANBJIASA-N 1143.92900 1142.28275 C[NH2+][C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C([O-])=O)c3O)c(Cl)c2 MetaCyc:CPD-15745 PMID:11470430 chebi_ontology CHEBI:75954 vancomycin aglycone zwitterion CHEBI:75954 MetaCyc:CPD-15745 SUBMITTER PMID:11470430 SUBMITTER An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid. 0 C2H4NO2R 74.059 74.02420 [NH3+]C([*])C([O-])=O MetaCyc:Aromatic-Amino-Acids chebi_ontology an aromatic amino-acid aromatic amino-acid zwitterions CHEBI:76042 aromatic amino-acid zwitterion CHEBI:76042 MetaCyc:Aromatic-Amino-Acids SUBMITTER an aromatic amino-acid UniProt aromatic amino-acid zwitterions ChEBI Any metabolite produced by metabolism of a xenobiotic compound. chebi_ontology xenobiotic metabolites CHEBI:76206 xenobiotic metabolite CHEBI:76206 xenobiotic metabolites ChEBI An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). Wikipedia:Histone_acetyltransferase chebi_ontology EC 2.3.1.48 (histone acetyltransferase) inhibitors EC 2.3.1.48 inhibitor EC 2.3.1.48 inhibitors HAT inhibitor HAT inhibitors acetyl-CoA:histone acetyltransferase inhibitor acetyl-CoA:histone acetyltransferase inhibitors histone acetokinase inhibitor histone acetokinase inhibitors histone acetylase inhibitor histone acetylase inhibitors histone acetyltransferase (EC 2.3.1.48) inhibitor histone acetyltransferase (EC 2.3.1.48) inhibitors histone acetyltransferase inhibitor histone acetyltransferase inhibitors histone transacetylase inhibitor histone transacetylase inhibitors nucleosome-histone acetyltransferase inhibitor nucleosome-histone acetyltransferase inhibitors CHEBI:76395 EC 2.3.1.48 (histone acetyltransferase) inhibitor CHEBI:76395 EC 2.3.1.48 (histone acetyltransferase) inhibitors ChEBI EC 2.3.1.48 inhibitor ChEBI EC 2.3.1.48 inhibitors ChEBI HAT inhibitor ChEBI HAT inhibitors ChEBI acetyl-CoA:histone acetyltransferase inhibitor ChEBI acetyl-CoA:histone acetyltransferase inhibitors ChEBI histone acetokinase inhibitor ChEBI histone acetokinase inhibitors ChEBI histone acetylase inhibitor ChEBI histone acetylase inhibitors ChEBI histone acetyltransferase (EC 2.3.1.48) inhibitor ChEBI histone acetyltransferase (EC 2.3.1.48) inhibitors ChEBI histone acetyltransferase inhibitor ChEBI histone acetyltransferase inhibitors ChEBI histone transacetylase inhibitor ChEBI histone transacetylase inhibitors ChEBI nucleosome-histone acetyltransferase inhibitor ChEBI nucleosome-histone acetyltransferase inhibitors ChEBI Any metabolite produced during a metabolic reaction in marine macro- and microorganisms. CHEBI:77078 chebi_ontology marine metabolites CHEBI:76507 marine metabolite CHEBI:76507 marine metabolites ChEBI Any unsaturated fatty acid anion containing more than one C-C unsaturated bond. Major species at pH 7.3. chebi_ontology PUFA polyunsaturated fatty acid anions CHEBI:76567 polyunsaturated fatty acid anion CHEBI:76567 PUFA SUBMITTER polyunsaturated fatty acid anions ChEBI A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections. 0 C47H75NO17 926.107 925.50350 CAS:1400-61-9 DrugBank:DB00646 Drug_Central:1977 KEGG:C06572 KEGG:D00202 LIPID_MAPS_instance:LMPK06000001 PMID:10427694 PMID:12987085 PMID:16374455 PMID:16740372 PMID:17422416 PMID:18551578 PMID:33141477 PMID:33279513 PMID:33387388 PMID:33389775 PMID:34033502 PMID:34160701 PMID:34657217 PMID:34714482 PMID:34738720 PMID:34946737 PMID:35178173 PMID:35195155 PMID:35299602 PMID:35549875 Wikipedia:Nystatin chebi_ontology Barstatin 100 Biofanal Candex Diastatin Fungicidin Herniocid Korostatin Mycostatin Nystex Nystop nystatin nystatina nystatine nystatinum CHEBI:7660 nystatin CHEBI:7660 CAS:1400-61-9 ChemIDplus Drug_Central:1977 DrugCentral LIPID_MAPS_instance:LMPK06000001 LIPID MAPS PMID:10427694 Europe PMC PMID:12987085 Europe PMC PMID:16374455 Europe PMC PMID:16740372 Europe PMC PMID:17422416 Europe PMC PMID:18551578 Europe PMC PMID:33141477 Europe PMC PMID:33279513 Europe PMC PMID:33387388 Europe PMC PMID:33389775 Europe PMC PMID:34033502 Europe PMC PMID:34160701 Europe PMC PMID:34657217 Europe PMC PMID:34714482 Europe PMC PMID:34738720 Europe PMC PMID:34946737 Europe PMC PMID:35178173 Europe PMC PMID:35195155 Europe PMC PMID:35299602 Europe PMC PMID:35549875 Europe PMC Barstatin 100 ChemIDplus Biofanal ChemIDplus Candex ChemIDplus Diastatin ChemIDplus Fungicidin ChemIDplus Herniocid ChemIDplus Korostatin ChemIDplus Mycostatin KEGG_DRUG Nystex ChemIDplus Nystop ChemIDplus nystatin WHO_MedNet nystatina WHO_MedNet nystatine WHO_MedNet nystatinum WHO_MedNet A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*). chebi_ontology EC 2.3.* (acyltransferase) inhibitors EC 2.3.* inhibitor EC 2.3.* inhibitors acyltransferase inhibitor acyltransferase inhibitors CHEBI:76661 EC 2.3.* (acyltransferase) inhibitor CHEBI:76661 EC 2.3.* (acyltransferase) inhibitors ChEBI EC 2.3.* inhibitor ChEBI EC 2.3.* inhibitors ChEBI acyltransferase inhibitor ChEBI acyltransferase inhibitors ChEBI A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*). chebi_ontology EC 2.4.* (glycosyltransferase) inhibitors EC 2.4.* inhibitor EC 2.4.* inhibitors glycosyltransferase (EC 2.4.*) inhibitor glycosyltransferase (EC 2.4.*) inhibitors glycosyltransferase inhibitor glycosyltransferase inhibitors CHEBI:76662 EC 2.4.* (glycosyltransferase) inhibitor CHEBI:76662 EC 2.4.* (glycosyltransferase) inhibitors ChEBI EC 2.4.* inhibitor ChEBI EC 2.4.* inhibitors ChEBI glycosyltransferase (EC 2.4.*) inhibitor ChEBI glycosyltransferase (EC 2.4.*) inhibitors ChEBI glycosyltransferase inhibitor ChEBI glycosyltransferase inhibitors ChEBI A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*). chebi_ontology EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors EC 2.5.1.* inhibitor EC 2.5.1.* inhibitors alkyl/aryl (non-methyl) transferase inhibitor alkyl/aryl (non-methyl) transferase inhibitors non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors non-methyl alkyl/aryl transferase inhibitor non-methyl alkyl/aryl transferase inhibitors non-methyl-alkyl or aryl transferase inhibitor non-methyl-alkyl or aryl transferase inhibitors CHEBI:76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor CHEBI:76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors ChEBI EC 2.5.1.* inhibitor ChEBI EC 2.5.1.* inhibitors ChEBI alkyl/aryl (non-methyl) transferase inhibitor ChEBI alkyl/aryl (non-methyl) transferase inhibitors ChEBI non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor ChEBI non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors ChEBI non-methyl alkyl/aryl transferase inhibitor ChEBI non-methyl alkyl/aryl transferase inhibitors ChEBI non-methyl-alkyl or aryl transferase inhibitor ChEBI non-methyl-alkyl or aryl transferase inhibitors ChEBI A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*). chebi_ontology EC 2.7.* (P-containing group transferase) inhibitors EC 2.7.* (phosphorus-containing group transferase) inhibitor EC 2.7.* (phosphorus-containing group transferase) inhibitors EC 2.7.* inhibitor EC 2.7.* inhibitors phosphorus-containing group transferase (EC 2.7.*) inhibitor phosphorus-containing group transferase (EC 2.7.*) inhibitors phosphorus-containing group transferase inhibitor phosphorus-containing group transferase inhibitors CHEBI:76668 EC 2.7.* (P-containing group transferase) inhibitor CHEBI:76668 EC 2.7.* (P-containing group transferase) inhibitors ChEBI EC 2.7.* (phosphorus-containing group transferase) inhibitor ChEBI EC 2.7.* (phosphorus-containing group transferase) inhibitors ChEBI EC 2.7.* inhibitor ChEBI EC 2.7.* inhibitors ChEBI phosphorus-containing group transferase (EC 2.7.*) inhibitor ChEBI phosphorus-containing group transferase (EC 2.7.*) inhibitors ChEBI phosphorus-containing group transferase inhibitor ChEBI phosphorus-containing group transferase inhibitors ChEBI An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*). chebi_ontology EC 5.99.* (miscellaneous isomerases) inhibitor EC 5.99.* (miscellaneous isomerases) inhibitors EC 5.99.* (other isomerase) inhibitor EC 5.99.* (other isomerase) inhibitors EC 5.99.* (other isomerases) inhibitors EC 5.99.* inhibitor EC 5.99.* inhibitors CHEBI:76697 EC 5.99.* (other isomerases) inhibitor CHEBI:76697 EC 5.99.* (miscellaneous isomerases) inhibitor ChEBI EC 5.99.* (miscellaneous isomerases) inhibitors ChEBI EC 5.99.* (other isomerase) inhibitor ChEBI EC 5.99.* (other isomerase) inhibitors ChEBI EC 5.99.* (other isomerases) inhibitors ChEBI EC 5.99.* inhibitor ChEBI EC 5.99.* inhibitors ChEBI An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation. Wikipedia:Lyase chebi_ontology EC 4.* (lyase) inhibitors EC 4.* inhibitor EC 4.* inhibitors EC 4.*.*.* inhibitor EC 4.*.*.* inhibitors lyase (EC 4.*) inhibitor lyase (EC 4.*) inhibitorS lyase inhibitor lyase inhibitors CHEBI:76710 EC 4.* (lyase) inhibitor CHEBI:76710 EC 4.* (lyase) inhibitors ChEBI EC 4.* inhibitor ChEBI EC 4.* inhibitors ChEBI EC 4.*.*.* inhibitor ChEBI EC 4.*.*.* inhibitors ChEBI lyase (EC 4.*) inhibitor ChEBI lyase (EC 4.*) inhibitorS ChEBI lyase inhibitor ChEBI lyase inhibitors ChEBI A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*). chebi_ontology C-O lyase (EC 4.2.*) inhibitor C-O lyase (EC 4.2.*) inhibitors C-O lyase inhibitor C-O lyase inhibitors EC 4.2.* (C-O lyase) inhibitors EC 4.2.* inhibitor EC 4.2.* inhibitors CHEBI:76712 EC 4.2.* (C-O lyase) inhibitor CHEBI:76712 C-O lyase (EC 4.2.*) inhibitor ChEBI C-O lyase (EC 4.2.*) inhibitors ChEBI C-O lyase inhibitor ChEBI C-O lyase inhibitors ChEBI EC 4.2.* (C-O lyase) inhibitors ChEBI EC 4.2.* inhibitor ChEBI EC 4.2.* inhibitors ChEBI An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*). Wikipedia:Oxidoreductase chebi_ontology EC 1.* (oxidoreductase) inhibitors EC 1.* inhibitor EC 1.* inhibitors oxidoreductase (EC 1.*) inhibitor oxidoreductase (EC 1.*) inhibitors oxidoreductase inhibitor oxidoreductase inhibitors CHEBI:76725 EC 1.* (oxidoreductase) inhibitor CHEBI:76725 EC 1.* (oxidoreductase) inhibitors ChEBI EC 1.* inhibitor ChEBI EC 1.* inhibitors ChEBI oxidoreductase (EC 1.*) inhibitor ChEBI oxidoreductase (EC 1.*) inhibitors ChEBI oxidoreductase inhibitor ChEBI oxidoreductase inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*). chebi_ontology EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors EC 1.2.* inhibitor EC 1.2.* inhibitors inhibitor of oxidoreductase acting on aldehyde or oxo group of donor inhibitor of oxidoreductase acting on aldehyde or oxo group of donors inhibitor of oxidoreductase acting on aldehyde/oxo group of donor inhibitor of oxidoreductase acting on aldehyde/oxo group of donors inhibitors of oxidoreductase acting on aldehyde or oxo group of donor inhibitors of oxidoreductase acting on aldehyde or oxo group of donors inhibitors of oxidoreductase acting on aldehyde/oxo group of donor inhibitors of oxidoreductase acting on aldehyde/oxo group of donors oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors oxidoreductase acting on donor aldehyde or oxo group inhibitor oxidoreductase acting on donor aldehyde or oxo group inhibitors oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors oxidoreductase acting on donor aldehyde/oxo group inhibitor oxidoreductase acting on donor aldehyde/oxo group inhibitors CHEBI:76727 EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor CHEBI:76727 EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor ChEBI EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors ChEBI EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors ChEBI EC 1.2.* inhibitor ChEBI EC 1.2.* inhibitors ChEBI inhibitor of oxidoreductase acting on aldehyde or oxo group of donor ChEBI inhibitor of oxidoreductase acting on aldehyde or oxo group of donors ChEBI inhibitor of oxidoreductase acting on aldehyde/oxo group of donor ChEBI inhibitor of oxidoreductase acting on aldehyde/oxo group of donors ChEBI inhibitors of oxidoreductase acting on aldehyde or oxo group of donor ChEBI inhibitors of oxidoreductase acting on aldehyde or oxo group of donors ChEBI inhibitors of oxidoreductase acting on aldehyde/oxo group of donor ChEBI inhibitors of oxidoreductase acting on aldehyde/oxo group of donors ChEBI oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor ChEBI oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors ChEBI oxidoreductase acting on donor aldehyde or oxo group inhibitor ChEBI oxidoreductase acting on donor aldehyde or oxo group inhibitors ChEBI oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor ChEBI oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors ChEBI oxidoreductase acting on donor aldehyde/oxo group inhibitor ChEBI oxidoreductase acting on donor aldehyde/oxo group inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*). chebi_ontology EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors EC 1.3.* inhibitor EC 1.3.* inhibitors inhibitor of oxidoreductase acting on CH-CH group of donor inhibitor of oxidoreductase acting on CH-CH group of donors inhibitors of oxidoreductase acting on CH-CH group of donor inhibitors of oxidoreductase acting on CH-CH group of donors oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors oxidoreductase acting on donor CH-CH group inhibitor oxidoreductase acting on donor CH-CH group inhibitors CHEBI:76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor CHEBI:76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors ChEBI EC 1.3.* inhibitor ChEBI EC 1.3.* inhibitors ChEBI inhibitor of oxidoreductase acting on CH-CH group of donor ChEBI inhibitor of oxidoreductase acting on CH-CH group of donors ChEBI inhibitors of oxidoreductase acting on CH-CH group of donor ChEBI inhibitors of oxidoreductase acting on CH-CH group of donors ChEBI oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor ChEBI oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors ChEBI oxidoreductase acting on donor CH-CH group inhibitor ChEBI oxidoreductase acting on donor CH-CH group inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*). EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor chebi_ontology EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors EC 1.4.* inhibitor EC 1.4.* inhibitors inhibitor of oxidoreductase acting on CH-NH2 group of donor inhibitor of oxidoreductase acting on CH-NH2 group of donors inhibitors of oxidoreductase acting on CH-NH2 group of donor inhibitors of oxidoreductase acting on CH-NH2 group of donors oxidoreductase acting on CH-NH2 group of donor inhibitor oxidoreductase acting on CH-NH2 group of donor inhibitors oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors CHEBI:76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor CHEBI:76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor ChEBI EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors ChEBI EC 1.4.* inhibitor ChEBI EC 1.4.* inhibitors ChEBI inhibitor of oxidoreductase acting on CH-NH2 group of donor ChEBI inhibitor of oxidoreductase acting on CH-NH2 group of donors ChEBI inhibitors of oxidoreductase acting on CH-NH2 group of donor ChEBI inhibitors of oxidoreductase acting on CH-NH2 group of donors ChEBI oxidoreductase acting on CH-NH2 group of donor inhibitor ChEBI oxidoreductase acting on CH-NH2 group of donor inhibitors ChEBI oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor ChEBI oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*). chebi_ontology EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors EC 1.5.* inhibitor EC 1.5.* inhibitors inhibitor of oxidoreductase acting on CH-NH group of donor inhibitor of oxidoreductase acting on CH-NH group of donors inhibitors of oxidoreductase acting on CH-NH group of donor inhibitors of oxidoreductase acting on CH-NH group of donors oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors CHEBI:76731 EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor CHEBI:76731 EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors ChEBI EC 1.5.* inhibitor ChEBI EC 1.5.* inhibitors ChEBI inhibitor of oxidoreductase acting on CH-NH group of donor ChEBI inhibitor of oxidoreductase acting on CH-NH group of donors ChEBI inhibitors of oxidoreductase acting on CH-NH group of donor ChEBI inhibitors of oxidoreductase acting on CH-NH group of donors ChEBI oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor ChEBI oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*). chebi_ontology EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors inhibitor of oxidoreductase acting on NADH or NADPH inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors of oxidoreductase acting on NADH or NADPH inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*) oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors oxidoreductase acting on NADH or NADPH inhibitor oxidoreductase acting on NADH or NADPH inhibitors CHEBI:76733 EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor CHEBI:76733 EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors ChEBI inhibitor of oxidoreductase acting on NADH or NADPH ChEBI inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*) ChEBI inhibitors of oxidoreductase acting on NADH or NADPH ChEBI inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*) ChEBI oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor ChEBI oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors ChEBI oxidoreductase acting on NADH or NADPH inhibitor ChEBI oxidoreductase acting on NADH or NADPH inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*). chebi_ontology EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors EC 1.9.* inhibitor EC 1.9.* inhibitors oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors CHEBI:76736 EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor CHEBI:76736 EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor ChEBI EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors ChEBI EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors ChEBI EC 1.9.* inhibitor ChEBI EC 1.9.* inhibitors ChEBI oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor ChEBI oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*). chebi_ontology EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors EC 1.11.* inhibitor EC 1.11.* inhibitors oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors CHEBI:76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor CHEBI:76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors ChEBI EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor ChEBI EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors ChEBI EC 1.11.* inhibitor ChEBI EC 1.11.* inhibitors ChEBI oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor ChEBI oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors ChEBI oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor ChEBI oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*. chebi_ontology EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors EC 1.13.* inhibitor EC 1.13.* inhibitors oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors CHEBI:76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor CHEBI:76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors ChEBI EC 1.13.* inhibitor ChEBI EC 1.13.* inhibitors ChEBI oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor ChEBI oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors ChEBI oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor ChEBI oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors ChEBI An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*). chebi_ontology EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors EC 1.14.* inhibitor EC 1.14.* inhibitors inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors CHEBI:76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor CHEBI:76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors ChEBI EC 1.14.* inhibitor ChEBI EC 1.14.* inhibitors ChEBI inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) ChEBI inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) ChEBI inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) ChEBI inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) ChEBI oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor ChEBI oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors ChEBI oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor ChEBI oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors ChEBI Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). Wikipedia:Hydrolase chebi_ontology EC 3.* (hydrolase) inhibitors EC 3.* inhibitor EC 3.* inhibitors EC 3.*.*.* inhibitor EC 3.*.*.* inhibitors hydrolase (EC 3.*) inhibitor hydrolase (EC 3.*) inhibitors hydrolase inhibitor hydrolase inhibitors CHEBI:76759 EC 3.* (hydrolase) inhibitor CHEBI:76759 EC 3.* (hydrolase) inhibitors ChEBI EC 3.* inhibitor ChEBI EC 3.* inhibitors ChEBI EC 3.*.*.* inhibitor ChEBI EC 3.*.*.* inhibitors ChEBI hydrolase (EC 3.*) inhibitor ChEBI hydrolase (EC 3.*) inhibitors ChEBI hydrolase inhibitor ChEBI hydrolase inhibitors ChEBI A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*). chebi_ontology EC 3.1.* (ester hydrolase) inhibitors EC 3.1.* inhibitor EC 3.1.* inhibitors ester hydrolase (EC 3.1.*) inhibitor ester hydrolase (EC 3.1.*) inhibitors ester hydrolase inhibitor ester hydrolase inhibitors CHEBI:76760 EC 3.1.* (ester hydrolase) inhibitor CHEBI:76760 EC 3.1.* (ester hydrolase) inhibitors ChEBI EC 3.1.* inhibitor ChEBI EC 3.1.* inhibitors ChEBI ester hydrolase (EC 3.1.*) inhibitor ChEBI ester hydrolase (EC 3.1.*) inhibitors ChEBI ester hydrolase inhibitor ChEBI ester hydrolase inhibitors ChEBI Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). chebi_ontology EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors EC 3.5.* inhibitor EC 3.5.* inhibitors CHEBI:76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor CHEBI:76764 EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor ChEBI EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors ChEBI EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor ChEBI EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors ChEBI EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors ChEBI EC 3.5.* inhibitor ChEBI EC 3.5.* inhibitors ChEBI An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*). chebi_ontology EC 3.1.1.* (carboxylic ester hydrolase) inhibitors EC 3.1.1.* inhibitor EC 3.1.1.* inhibitors carboxylic ester hydrolase (EC 3.1.1.*) inhibitor carboxylic ester hydrolase (EC 3.1.1.*) inhibitors CHEBI:76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor CHEBI:76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitors ChEBI EC 3.1.1.* inhibitor ChEBI EC 3.1.1.* inhibitors ChEBI carboxylic ester hydrolase (EC 3.1.1.*) inhibitor ChEBI carboxylic ester hydrolase (EC 3.1.1.*) inhibitors ChEBI An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*). chebi_ontology EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors EC 3.1.3.* inhibitor EC 3.1.3.* inhibitors inhibitor of phosphoric monoester hydrolase inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors of phosphoric monoester hydrolase inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*) phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors phosphoric monoester hydrolase inhibitor phosphoric monoester hydrolase inhibitors CHEBI:76775 EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor CHEBI:76775 EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors ChEBI EC 3.1.3.* inhibitor ChEBI EC 3.1.3.* inhibitors ChEBI inhibitor of phosphoric monoester hydrolase ChEBI inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*) ChEBI inhibitors of phosphoric monoester hydrolase ChEBI inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*) ChEBI phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor ChEBI phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors ChEBI phosphoric monoester hydrolase inhibitor ChEBI phosphoric monoester hydrolase inhibitors ChEBI An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*). chebi_ontology EC 2.4.1.* (hexosyltransferase) inhibitors EC 2.4.1.* inhibitor EC 2.4.1.* inhibitors hexosyltransferase (EC 2.4.1.*) inhibitor hexosyltransferase (EC 2.4.1.*) inhibitors hexosyltransferase inhibitor hexosyltransferase inhibitors CHEBI:76789 EC 2.4.1.* (hexosyltransferase) inhibitor CHEBI:76789 EC 2.4.1.* (hexosyltransferase) inhibitors ChEBI EC 2.4.1.* inhibitor ChEBI EC 2.4.1.* inhibitors ChEBI hexosyltransferase (EC 2.4.1.*) inhibitor ChEBI hexosyltransferase (EC 2.4.1.*) inhibitors ChEBI hexosyltransferase inhibitor ChEBI hexosyltransferase inhibitors ChEBI An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*). chebi_ontology EC 2.4.2.* (pentosyltransferase) inhibitors EC 2.4.2.* inhibitor EC 2.4.2.* inhibitors pentosyltransferase (EC 2.4.2.*) inhibitor pentosyltransferase (EC 2.4.2.*) inhibitors pentosyltransferase inhibitor pentosyltransferase inhibitors CHEBI:76790 EC 2.4.2.* (pentosyltransferase) inhibitor CHEBI:76790 EC 2.4.2.* (pentosyltransferase) inhibitors ChEBI EC 2.4.2.* inhibitor ChEBI EC 2.4.2.* inhibitors ChEBI pentosyltransferase (EC 2.4.2.*) inhibitor ChEBI pentosyltransferase (EC 2.4.2.*) inhibitors ChEBI pentosyltransferase inhibitor ChEBI pentosyltransferase inhibitors ChEBI An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). chebi_ontology EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors EC 3.5.1.* inhibitor EC 3.5.1.* inhibitors non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors CHEBI:76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor CHEBI:76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors ChEBI EC 3.5.1.* inhibitor ChEBI EC 3.5.1.* inhibitors ChEBI non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor ChEBI non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors ChEBI An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*). chebi_ontology EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors EC 3.5.2.* inhibitor EC 3.5.2.* inhibitors non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors non-peptide cyclic amide C-N hydrolase inhibitor non-peptide cyclic amide C-N hydrolase inhibitors CHEBI:76808 EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor CHEBI:76808 EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors ChEBI EC 3.5.2.* inhibitor ChEBI EC 3.5.2.* inhibitors ChEBI non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor ChEBI non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors ChEBI non-peptide cyclic amide C-N hydrolase inhibitor ChEBI non-peptide cyclic amide C-N hydrolase inhibitors ChEBI An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*). chebi_ontology EC 2.7.11.* (protein-serine/threonine kinase) inhibitors EC 2.7.11.* inhibitor EC 2.7.11.* inhibitors protein-serine/threonine kinase (EC 2.7.11.*) inhibitor protein-serine/threonine kinase (EC 2.7.11.*) inhibitors protein-serine/threonine kinase inhibitor protein-serine/threonine kinase inhibitors CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitors ChEBI EC 2.7.11.* inhibitor ChEBI EC 2.7.11.* inhibitors ChEBI protein-serine/threonine kinase (EC 2.7.11.*) inhibitor ChEBI protein-serine/threonine kinase (EC 2.7.11.*) inhibitors ChEBI protein-serine/threonine kinase inhibitor ChEBI protein-serine/threonine kinase inhibitors ChEBI An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*). chebi_ontology EC 2.7.7.* (nucleotidyltransferase) inhibitors inhibitor of nucleotidyltransferases inhibitor of nucleotidyltransferases (EC 2.7.7.*) inhibitors of nucleotidyltransferases inhibitors of nucleotidyltransferases (EC 2.7.7.*) nucleotidyltransferase (EC 2.7.7.*) inhibitor nucleotidyltransferase (EC 2.7.7.*) inhibitors nucleotidyltransferase inhibitor nucleotidyltransferase inhibitors CHEBI:76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor CHEBI:76815 EC 2.7.7.* (nucleotidyltransferase) inhibitors ChEBI inhibitor of nucleotidyltransferases ChEBI inhibitor of nucleotidyltransferases (EC 2.7.7.*) ChEBI inhibitors of nucleotidyltransferases ChEBI inhibitors of nucleotidyltransferases (EC 2.7.7.*) ChEBI nucleotidyltransferase (EC 2.7.7.*) inhibitor ChEBI nucleotidyltransferase (EC 2.7.7.*) inhibitors ChEBI nucleotidyltransferase inhibitor ChEBI nucleotidyltransferase inhibitors ChEBI An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category. chebi_ontology EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors EC 2.7.8.* inhibitor EC 2.7.8.* inhibitors CHEBI:76816 EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor CHEBI:76816 EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors ChEBI EC 2.7.8.* inhibitor ChEBI EC 2.7.8.* inhibitors ChEBI An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class. chebi_ontology EC 5.99.1.* (miscellaneous isomerase) inhibitors EC 5.99.1.* inhibitor EC 5.99.1.* inhibitors CHEBI:76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor CHEBI:76830 EC 5.99.1.* (miscellaneous isomerase) inhibitors ChEBI EC 5.99.1.* inhibitor ChEBI EC 5.99.1.* inhibitors ChEBI An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*). chebi_ontology EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors EC 2.5.* inhibitor EC 2.5.* inhibitors non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors CHEBI:76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor CHEBI:76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors ChEBI EC 2.5.* inhibitor ChEBI EC 2.5.* inhibitors ChEBI non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor ChEBI non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors ChEBI An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*). chebi_ontology EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors EC 1.13.11.* inhibitor EC 1.13.11.* inhibitors oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors CHEBI:76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor CHEBI:76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors ChEBI EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor ChEBI EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors ChEBI EC 1.13.11.* inhibitor ChEBI EC 1.13.11.* inhibitors ChEBI oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor ChEBI oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors ChEBI An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*). chebi_ontology EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors EC 1.14.14.* inhibitor EC 1.14.14.* inhibitors oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors CHEBI:76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor CHEBI:76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors ChEBI EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor ChEBI EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors ChEBI EC 1.14.14.* inhibitor ChEBI EC 1.14.14.* inhibitors ChEBI oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor ChEBI oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors ChEBI An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*). chebi_ontology EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors EC 1.14.13.* inhibitor EC 1.14.13.* inhibitors oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors CHEBI:76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor CHEBI:76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors ChEBI EC 1.14.13.* inhibitor ChEBI EC 1.14.13.* inhibitors ChEBI oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor ChEBI oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors ChEBI An organic cation that is the conjugate acid of vancomycin, obtained by deprotonation of the carboxy group and protonation of the two amino functions; major species at pH 7.3. +1 C66H76Cl2N9O24 InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)/p+1/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-/m0/s1 MYPYJXKWCTUITO-LYRMYLQWSA-O 1450.26100 1448.43748 C[NH2+][C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C([O-])=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1)c(Cl)c2 MetaCyc:CPD-12245 chebi_ontology vancomycin CHEBI:76842 vancomycin(1+) CHEBI:76842 MetaCyc:CPD-12245 SUBMITTER vancomycin UniProt An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*). chebi_ontology EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors EC 1.2.3.* inhibitor EC 1.2.3.* inhibitors oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors CHEBI:76853 EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor CHEBI:76853 EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors ChEBI EC 1.2.3.* inhibitor ChEBI EC 1.2.3.* inhibitors ChEBI oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor ChEBI oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors ChEBI An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*). chebi_ontology EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors EC 1.3.1.* inhibitor EC 1.3.1.* inhibitors oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors CHEBI:76857 EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor CHEBI:76857 EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor ChEBI EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors ChEBI EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor ChEBI EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors ChEBI EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors ChEBI EC 1.3.1.* inhibitor ChEBI EC 1.3.1.* inhibitors ChEBI oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor ChEBI oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors ChEBI An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*). chebi_ontology EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors EC 1.4.3.* inhibitor EC 1.4.3.* inhibitors oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors CHEBI:76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor CHEBI:76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors ChEBI EC 1.4.3.* inhibitor ChEBI EC 1.4.3.* inhibitors ChEBI oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor ChEBI oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors ChEBI An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*). chebi_ontology EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors EC 1.5.1.* inhibitor EC 1.5.1.* inhibitors oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors CHEBI:76863 EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor CHEBI:76863 EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors ChEBI EC 1.5.1.* inhibitor ChEBI EC 1.5.1.* inhibitors ChEBI oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor ChEBI oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors ChEBI An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*). chebi_ontology EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors EC 1.6.5.* inhibitor EC 1.6.5.* inhibitors oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors CHEBI:76866 EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor CHEBI:76866 EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors ChEBI EC 1.6.5.* inhibitor ChEBI EC 1.6.5.* inhibitors ChEBI oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor ChEBI oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors ChEBI An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*). chebi_ontology EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors EC 1.9.3.* inhibitor EC 1.9.3.* inhibitors oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors CHEBI:76870 EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor CHEBI:76870 EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors ChEBI EC 1.9.3.* inhibitor ChEBI EC 1.9.3.* inhibitors ChEBI oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor ChEBI oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors ChEBI An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*). chebi_ontology EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors EC 2.3.1.* inhibitor EC 2.3.1.* inhibitors acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors CHEBI:76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor CHEBI:76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors ChEBI EC 2.3.1.* inhibitor ChEBI EC 2.3.1.* inhibitors ChEBI acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor ChEBI acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors ChEBI An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*). chebi_ontology EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors EC 2.7.1.* inhibitor EC 2.7.1.* inhibitors phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors CHEBI:76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor CHEBI:76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors ChEBI EC 2.7.1.* inhibitor ChEBI EC 2.7.1.* inhibitors ChEBI phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor ChEBI phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors ChEBI An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*). chebi_ontology EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors EC 3.6.3.* inhibitor EC 3.6.3.* inhibitors acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors CHEBI:76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor CHEBI:76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors ChEBI EC 3.6.3.* inhibitor ChEBI EC 3.6.3.* inhibitors ChEBI acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor ChEBI acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors ChEBI An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1). chebi_ontology EC 1.14.14.1 (unspecific monooxygenase) inhibitors EC 1.14.14.1 inhibitor EC 1.14.14.1 inhibitors aryl hydrocarbon hydroxylase inhibitor aryl hydrocarbon hydroxylase inhibitors aryl-4-monooxygenase inhibitor aryl-4-monooxygenase inhibitors flavoprotein monooxygenase inhibitor flavoprotein monooxygenase inhibitors flavoprotein-linked monooxygenase inhibitor flavoprotein-linked monooxygenase inhibitors microsomal P-450 inhibitor microsomal P-450 inhibitors microsomal monooxygenase inhibitor microsomal monooxygenase inhibitors substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors unspecific monooxygenase (EC 1.14.14.1) inhibitor unspecific monooxygenase (EC 1.14.14.1) inhibitors unspecific monooxygenase inhibitor unspecific monooxygenase inhibitors xenobiotic monooxygenase inhibitor xenobiotic monooxygenase inhibitors CHEBI:76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor CHEBI:76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitors ChEBI EC 1.14.14.1 inhibitor ChEBI EC 1.14.14.1 inhibitors ChEBI aryl hydrocarbon hydroxylase inhibitor ChEBI aryl hydrocarbon hydroxylase inhibitors ChEBI aryl-4-monooxygenase inhibitor ChEBI aryl-4-monooxygenase inhibitors ChEBI flavoprotein monooxygenase inhibitor ChEBI flavoprotein monooxygenase inhibitors ChEBI flavoprotein-linked monooxygenase inhibitor ChEBI flavoprotein-linked monooxygenase inhibitors ChEBI microsomal P-450 inhibitor ChEBI microsomal P-450 inhibitors ChEBI microsomal monooxygenase inhibitor ChEBI microsomal monooxygenase inhibitors ChEBI substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor ChEBI substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors ChEBI unspecific monooxygenase (EC 1.14.14.1) inhibitor ChEBI unspecific monooxygenase (EC 1.14.14.1) inhibitors ChEBI unspecific monooxygenase inhibitor ChEBI unspecific monooxygenase inhibitors ChEBI xenobiotic monooxygenase inhibitor ChEBI xenobiotic monooxygenase inhibitors ChEBI An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*). chebi_ontology EC 4.2.1.* (hydro-lyase) inhibitor EC 4.2.1.* (hydro-lyase) inhibitors EC 4.2.1.* (hydro-lyases) inhibitors EC 4.2.1.* inhibitor EC 4.2.1.* inhibitors hydro-lyase (EC 4.2.1.*) inhibitor hydro-lyase (EC 4.2.1.*) inhibitors CHEBI:76907 EC 4.2.1.* (hydro-lyases) inhibitor CHEBI:76907 EC 4.2.1.* (hydro-lyase) inhibitor ChEBI EC 4.2.1.* (hydro-lyase) inhibitors ChEBI EC 4.2.1.* (hydro-lyases) inhibitors ChEBI EC 4.2.1.* inhibitor ChEBI EC 4.2.1.* inhibitors ChEBI hydro-lyase (EC 4.2.1.*) inhibitor ChEBI hydro-lyase (EC 4.2.1.*) inhibitors ChEBI Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. CHEBI:75766 CHEBI:76925 chebi_ontology plant metabolites plant secondary metabolites CHEBI:76924 plant metabolite CHEBI:76924 plant metabolites ChEBI plant secondary metabolites ChEBI An enzyme inhibitor that interferes with one or more steps in a metabolic pathway. chebi_ontology metabolic pathway inhibitor metabolic pathway inhibitors pathway inhibitors CHEBI:76932 pathway inhibitor CHEBI:76932 metabolic pathway inhibitor ChEBI metabolic pathway inhibitors ChEBI pathway inhibitors ChEBI Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. CHEBI:75765 CHEBI:76947 chebi_ontology fungal metabolites CHEBI:76946 fungal metabolite CHEBI:76946 fungal metabolites ChEBI Any fungal metabolite produced during a metabolic reaction in Penicillium. CHEBI:76205 CHEBI:76963 chebi_ontology Penicillium metabolites CHEBI:76964 Penicillium metabolite CHEBI:76964 Penicillium metabolites ChEBI Any human metabolite produced by metabolism of a xenobiotic compound in humans. chebi_ontology human xenobiotic metabolites CHEBI:76967 human xenobiotic metabolite CHEBI:76967 human xenobiotic metabolites ChEBI Any prokaryotic metabolite produced during a metabolic reaction in bacteria. CHEBI:75760 CHEBI:76970 chebi_ontology CHEBI:76969 bacterial metabolite CHEBI:76969 Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. chebi_ontology E.coli metabolite E.coli metabolites Escherichia coli metabolites CHEBI:76971 Escherichia coli metabolite CHEBI:76971 E.coli metabolite ChEBI E.coli metabolites ChEBI Escherichia coli metabolites ChEBI An organic cation that is the conjugate acid of tylosin, obtained by protonation of the tertiary amino group; major species at pH 7.3. +1 C46H78NO17 InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/p+1/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1 WBPYTXDJUQJLPQ-VMXQISHHSA-O 917.10750 916.52643 CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)[NH+](C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylazaniumyl)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside chebi_ontology tylosin CHEBI:77047 tylosin(1+) CHEBI:77047 [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylazaniumyl)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside IUPAC tylosin UniProt A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections. CAS:57808-65-8 KEGG:D03567 PMID:21247019 PMID:22916226 PMID:23992251 PMID:3330516 PMID:4054009 PMID:7119989 PMID:7571353 PMID:9138034 Patent:BE839481 Patent:US4005218 Reaxys:6249214 rac-N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide chebi_ontology 5'-chloro-alpha(4)-(p-chlorophenyl)-alpha(4)-cyano-3,5-diiodo-2',4'-salicyloxylidide Flukiver R 31,520 R 31520 Seponver closantel closantelum CHEBI:77053 closantel CHEBI:77053 CAS:57808-65-8 ChemIDplus CAS:57808-65-8 KEGG DRUG PMID:21247019 Europe PMC PMID:22916226 Europe PMC PMID:23992251 Europe PMC PMID:3330516 Europe PMC PMID:4054009 Europe PMC PMID:7119989 Europe PMC PMID:7571353 Europe PMC PMID:9138034 Europe PMC Reaxys:6249214 Reaxys rac-N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide IUPAC 5'-chloro-alpha(4)-(p-chlorophenyl)-alpha(4)-cyano-3,5-diiodo-2',4'-salicyloxylidide ChemIDplus Flukiver ChEBI R 31,520 ChemIDplus R 31520 ChemIDplus Seponver ChEBI closantel WHO_MedNet closantelum WHO_MedNet An aromatic amide resulting from the formal condensation of the carboxy group of 3,5-diiodosalicylic acid with the amino group of aniline substituted at positions 2, 4, and 5 by methyl, (4-chlorophenyl)(cyano)methyl, and methyl groups respectively. 0 C22H14Cl2I2N2O2 InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30) JMPFSEBWVLAJKM-UHFFFAOYSA-N 663.07400 661.85217 Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O LINCS:LSM-4989 VSDB:1809 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide chebi_ontology CHEBI:77054 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide CHEBI:77054 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide IUPAC An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has R configuration. 0 C22H14Cl2I2N2O2 InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)/t17-/m1/s1 JMPFSEBWVLAJKM-QGZVFWFLSA-N 663.07400 661.85217 Cc1cc([C@H](C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O N-{5-chloro-4-[(R)-(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide chebi_ontology CHEBI:77056 (R)-closantel CHEBI:77056 N-{5-chloro-4-[(R)-(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide IUPAC An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has S configuration. 0 C22H14Cl2I2N2O2 InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)/t17-/m0/s1 JMPFSEBWVLAJKM-KRWDZBQOSA-N 663.07400 661.85217 Cc1cc([C@@H](C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O N-{5-chloro-4-[(S)-(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide chebi_ontology CHEBI:77057 (S)-closantel CHEBI:77057 N-{5-chloro-4-[(S)-(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide IUPAC An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*). chebi_ontology EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors EC 1.3.5.* inhibitor EC 1.3.5.* inhibitors inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors CHEBI:77102 EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor CHEBI:77102 EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors ChEBI EC 1.3.5.* inhibitor ChEBI EC 1.3.5.* inhibitors ChEBI inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor ChEBI inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) ChEBI inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor ChEBI inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) ChEBI oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor ChEBI oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors ChEBI An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33). Wikipedia:Pantothenate_kinase chebi_ontology ATP:(R)-pantothenate 4'-phosphotransferase inhibitor ATP:(R)-pantothenate 4'-phosphotransferase inhibitors ATP:pantothenate 4'-phosphotransferase inhibitor ATP:pantothenate 4'-phosphotransferase inhibitors D-pantothenate kinase inhibitor D-pantothenate kinase inhibitors EC 2.7.1.33 (pantothenate kinase) inhibitors EC 2.7.1.33 inhibitor EC 2.7.1.33 inhibitors pantothenate kinase (EC 2.7.1.33) inhibitor pantothenate kinase (EC 2.7.1.33) inhibitors pantothenate kinase (phosphorylating) inhibitor pantothenate kinase (phosphorylating) inhibitors pantothenic acid kinase inhibitor pantothenic acid kinase inhibitors CHEBI:77194 EC 2.7.1.33 (pantothenate kinase) inhibitor CHEBI:77194 ATP:(R)-pantothenate 4'-phosphotransferase inhibitor ChEBI ATP:(R)-pantothenate 4'-phosphotransferase inhibitors ChEBI ATP:pantothenate 4'-phosphotransferase inhibitor ChEBI ATP:pantothenate 4'-phosphotransferase inhibitors ChEBI D-pantothenate kinase inhibitor ChEBI D-pantothenate kinase inhibitors ChEBI EC 2.7.1.33 (pantothenate kinase) inhibitors ChEBI EC 2.7.1.33 inhibitor ChEBI EC 2.7.1.33 inhibitors ChEBI pantothenate kinase (EC 2.7.1.33) inhibitor ChEBI pantothenate kinase (EC 2.7.1.33) inhibitors ChEBI pantothenate kinase (phosphorylating) inhibitor ChEBI pantothenate kinase (phosphorylating) inhibitors ChEBI pantothenic acid kinase inhibitor ChEBI pantothenic acid kinase inhibitors ChEBI An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83). Wikipedia:Anthrax_lethal_factor_endopeptidase chebi_ontology EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors EC 3.4.24.83 inhibitor EC 3.4.24.83 inhibitors anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors lethal toxin inhibitor lethal toxin inhibitors CHEBI:77255 EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor CHEBI:77255 EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors ChEBI EC 3.4.24.83 inhibitor ChEBI EC 3.4.24.83 inhibitors ChEBI anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor ChEBI anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors ChEBI lethal toxin inhibitor ChEBI lethal toxin inhibitors ChEBI A member of the class of dithiocarbamate anions resulting from the deprotonation of both of the dithiocarbamic acid moieties of ethylenebis(dithiocarbamic acid). The major species at pH 7.3. -2 C4H6N2S4 InChI=1S/C4H8N2S4/c7-3(8)5-1-2-6-4(9)10/h1-2H2,(H2,5,7,8)(H2,6,9,10)/p-2 AWYFNIZYMPNGAI-UHFFFAOYSA-L 210.36500 209.94248 [S-]C(=S)NCCNC([S-])=S ethane-1,2-diyldicarbamodithioate chebi_ontology ethylenebis(dithiocarbamic acid)(2-) CHEBI:77308 ethylenebis(dithiocarbamate) CHEBI:77308 ethane-1,2-diyldicarbamodithioate IUPAC ethylenebis(dithiocarbamic acid)(2-) ChEBI A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. 0 C18H20FN3O4 361.373 361.14378 CHEBI:100146 CAS:82419-36-1 DrugBank:DB01165 Drug_Central:1981 HMDB:HMDB0015296 KEGG:C07321 KEGG:D00453 LINCS:LSM-4370 MetaCyc:CPD-12843 PMID:11710934 PMID:11903499 PMID:12827054 PMID:15008519 PMID:15557076 PMID:16669862 PMID:1804789 PMID:19646516 PMID:24497308 PMID:24550337 PMID:3469159 PMID:3546152 PMID:35897550 PMID:36004580 PMID:36228398 PMID:36268299 PMID:6960805 PMID:7884650 PMID:9228220 Reaxys:3657947 VSDB:1898 Wikipedia:Ofloxacin rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid chebi_ontology (+-)-ofloxacin (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid DL 8280 DL-8280 Exocin Floxin Gailuoxian HOE 280 HOE-280 OFLX ORF 18489 Ocuflox Oxaldin Prifloxcin Prifloxin Tarivid Visiren ofloxacin ofloxacine ofloxacino ofloxacinum rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid rac-ofloxacin racemic ofloxacin CHEBI:7731 ofloxacin CHEBI:7731 CAS:82419-36-1 ChemIDplus CAS:82419-36-1 KEGG COMPOUND Drug_Central:1981 DrugCentral PMID:11710934 Europe PMC PMID:11903499 Europe PMC PMID:12827054 Europe PMC PMID:15008519 Europe PMC PMID:15557076 Europe PMC PMID:16669862 Europe PMC PMID:1804789 Europe PMC PMID:19646516 Europe PMC PMID:24497308 Europe PMC PMID:24550337 Europe PMC PMID:3469159 Europe PMC PMID:3546152 Europe PMC PMID:35897550 Europe PMC PMID:36004580 Europe PMC PMID:36228398 Europe PMC PMID:36268299 Europe PMC PMID:6960805 Europe PMC PMID:7884650 Europe PMC PMID:9228220 Europe PMC Reaxys:3657947 Reaxys rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid IUPAC (+-)-ofloxacin ChEBI (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid IUPAC DL 8280 ChemIDplus DL-8280 ChemIDplus Exocin ChEBI Floxin KEGG_DRUG Gailuoxian DrugCentral HOE 280 DrugBank HOE-280 DrugBank OFLX KEGG_DRUG ORF 18489 ChemIDplus Ocuflox ChemIDplus Oxaldin ChemIDplus Prifloxcin DrugCentral Prifloxin DrugCentral Tarivid ChemIDplus Visiren ChemIDplus ofloxacin WHO_MedNet ofloxacine WHO_MedNet ofloxacino WHO_MedNet ofloxacinum WHO_MedNet rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid ChEBI rac-ofloxacin ChEBI racemic ofloxacin ChEBI An organic cation obtained by protonation of the secondary amino groups of spectinomycin. +2 C14H26N2O7 InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/p+2/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1 UNFWWIHTNXNPBV-WXKVUWSESA-P 334.36430 334.17290 C[NH2+][C@@H]1[C@H](O)[C@H]([NH2+]C)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-N,N',2-trimethyl-4-oxodecahydro-2H-pyrano[2,3-b][1,4]benzodioxine-6,8-diaminium chebi_ontology spectinomycin dication CHEBI:77315 spectinomycin(2+) CHEBI:77315 (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-N,N',2-trimethyl-4-oxodecahydro-2H-pyrano[2,3-b][1,4]benzodioxine-6,8-diaminium IUPAC spectinomycin dication ChEBI An agonist that selectively binds to and activates a pregnane X receptor. Wikipedia:Pregnane_X_receptor chebi_ontology PXR agonist PXR agonists pregnane X receptor agonists CHEBI:77318 pregnane X receptor agonist CHEBI:77318 PXR agonist ChEBI PXR agonists ChEBI pregnane X receptor agonists ChEBI An organic cation that is the conjugate acid of trovafloxacin, obtained by protonation of the primary amino group. +1 C20H16F3N4O3 InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/p+1/t10-,11+,16+ WVPSKSLAZQPAKQ-CDMJZVDBSA-O 417.36070 417.11690 [NH3+][C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F (1R,5S,6s)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hexan-6-aminium chebi_ontology trovafloxacin cation CHEBI:77569 trovafloxacin(1+) CHEBI:77569 (1R,5S,6s)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hexan-6-aminium IUPAC trovafloxacin cation ChEBI An organic cation that is the conjugate acid of terbinafine, obtained by protonation of the amino group; major species at pH 7.3. +1 C21H26N InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/p+1/b9-5+ DOMXUEMWDBAQBQ-WEVVVXLNSA-O 292.43730 292.20598 C[NH+](C\C=C\C#CC(C)(C)C)Cc1cccc2ccccc12 (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-aminium chebi_ontology terbinafine cation CHEBI:77615 terbinafine(1+) CHEBI:77615 (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-aminium IUPAC terbinafine cation ChEBI Any iminium ion resulting from the protonation of a carboxamidine. chebi_ontology carboxamidinium ions CHEBI:77718 carboxamidinium ion CHEBI:77718 carboxamidinium ions ChEBI A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group. 0 C27H38N2O4 InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3 SGTNSNPWRIOYBX-UHFFFAOYSA-N 454.60160 454.28316 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC CAS:52-53-9 KEGG:C07188 KEGG:D02356 LINCS:LSM-1298 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile chebi_ontology CHEBI:77733 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile CHEBI:77733 CAS:52-53-9 KEGG COMPOUND 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile IUPAC A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil. 0 C27H38N2O4 InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/t27-/m1/s1 SGTNSNPWRIOYBX-HHHXNRCGSA-N 454.60160 454.28316 COc1ccc(CCN(C)CCC[C@@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC CAS:38321-02-7 PMID:7636539 PMID:8698736 PMID:8698738 PMID:8698739 PMID:8698740 PMID:8712693 Reaxys:3657914 (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile chebi_ontology (+)-(2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile (+)-(R)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile (+)-(R)-verapamil (+)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile (+)-3-(3,4-dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile (+)-verapamil (2R)-(+)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile (R)-(+)-verapamil (R)-verapamil dexverapamil dexverapamilo dexverapamilum CHEBI:77734 dexverapamil CHEBI:77734 CAS:38321-02-7 ChemIDplus PMID:7636539 Europe PMC PMID:8698736 Europe PMC PMID:8698738 Europe PMC PMID:8698739 Europe PMC PMID:8698740 Europe PMC PMID:8712693 Europe PMC Reaxys:3657914 Reaxys (2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile IUPAC (+)-(2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile ChEBI (+)-(R)-5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile ChemIDplus (+)-(R)-verapamil ChEBI (+)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile ChEBI (+)-3-(3,4-dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile ChEBI (+)-verapamil ChEBI (2R)-(+)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile ChEBI (R)-(+)-verapamil ChEBI (R)-verapamil ChEBI dexverapamil WHO_MedNet dexverapamilo WHO_MedNet dexverapamilum WHO_MedNet A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has S configuration. 0 C27H38N2O4 InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/t27-/m0/s1 SGTNSNPWRIOYBX-MHZLTWQESA-N 454.60160 454.28316 COc1ccc(CCN(C)CCC[C@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC Reaxys:5314473 (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile chebi_ontology (-)-(S)-verapamil (-)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile (-)-verapamil (S)-(-)-verapamil CHEBI:77736 (S)-verapamil CHEBI:77736 Reaxys:5314473 Reaxys (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile IUPAC (-)-(S)-verapamil ChEBI (-)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile ChEBI (-)-verapamil ChEBI (S)-(-)-verapamil ChEBI An ammonium ion resulting from the protonation of the tertiary amino group of dexverapamil. +1 C27H39N2O4 InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/p+1/t27-/m1/s1 SGTNSNPWRIOYBX-HHHXNRCGSA-O 455.60900 455.29043 COc1ccc(CC[NH+](C)CCC[C@@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC (4R)-4-cyano-4-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N,5-dimethylhexan-1-aminium chebi_ontology (R)-verapamil(1+) CHEBI:77737 dexverapamil(1+) CHEBI:77737 (4R)-4-cyano-4-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N,5-dimethylhexan-1-aminium IUPAC (R)-verapamil(1+) ChEBI An ammonium ion resulting from the protonation of the tertiary amino group of (S)-verapamil. (4S)-4-cyano-4-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N,5-dimethylhexan-1-aminium (S)-verapamil(1+) chebi_ontology CHEBI:77738 (S)-verapamil(1+) CHEBI:77738 (4S)-4-cyano-4-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N,5-dimethylhexan-1-aminium IUPAC (S)-verapamil(1+) ChEBI An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18). Wikipedia:Meprin_A chebi_ontology EC 3.4.24.18 (meprin A) inhibitors EC 3.4.24.18 inhibitor EC 3.4.24.18 inhibitors N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors PABA-peptide hydrolase inhibitor PABA-peptide hydrolase inhibitors PPH inhibitor PPH inhibitors endopeptidase-2 inhibitor endopeptidase-2 inhibitors meprin A (EC 3.4.24.18) inhibitor meprin A (EC 3.4.24.18) inhibitors meprin A inhibitor meprin A inhibitors meprin inhibitor meprin inhibitors meprin-a inhibitor meprin-a inhibitors CHEBI:77745 EC 3.4.24.18 (meprin A) inhibitor CHEBI:77745 EC 3.4.24.18 (meprin A) inhibitors ChEBI EC 3.4.24.18 inhibitor ChEBI EC 3.4.24.18 inhibitors ChEBI N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor ChEBI N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors ChEBI PABA-peptide hydrolase inhibitor ChEBI PABA-peptide hydrolase inhibitors ChEBI PPH inhibitor ChEBI PPH inhibitors ChEBI endopeptidase-2 inhibitor ChEBI endopeptidase-2 inhibitors ChEBI meprin A (EC 3.4.24.18) inhibitor ChEBI meprin A (EC 3.4.24.18) inhibitors ChEBI meprin A inhibitor ChEBI meprin A inhibitors ChEBI meprin inhibitor ChEBI meprin inhibitors ChEBI meprin-a inhibitor ChEBI meprin-a inhibitors ChEBI Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). CHEBI:75770 CHEBI:77123 chebi_ontology H. sapiens metabolite H. sapiens metabolites Homo sapiens metabolite Homo sapiens metabolites CHEBI:77746 human metabolite CHEBI:77746 H. sapiens metabolite ChEBI H. sapiens metabolites ChEBI Homo sapiens metabolite ChEBI Homo sapiens metabolites ChEBI An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1). Wikipedia:Phospholipid-translocating_ATPase chebi_ontology ATP phosphohydrolase (phospholipid-flipping) inhibitor ATP phosphohydrolase (phospholipid-flipping) inhibitors EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors EC 3.6.3.1 inhibitor EC 3.6.3.1 inhibitors Mg(2)(+)-ATPase inhibitor Mg(2)(+)-ATPase inhibitors aminophospholipid-transporting ATPase inhibitor aminophospholipid-transporting ATPase inhibitors flippase inhibitor flippase inhibitors magnesium-ATPase inhibitor magnesium-ATPase inhibitors phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors phospholipid-translocating ATPase inhibitor phospholipid-translocating ATPase inhibitors phospholipid-transporting ATPase inhibitor phospholipid-transporting ATPase inhibitors CHEBI:77747 EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor CHEBI:77747 ATP phosphohydrolase (phospholipid-flipping) inhibitor ChEBI ATP phosphohydrolase (phospholipid-flipping) inhibitors ChEBI EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors ChEBI EC 3.6.3.1 inhibitor ChEBI EC 3.6.3.1 inhibitors ChEBI Mg(2)(+)-ATPase inhibitor ChEBI Mg(2)(+)-ATPase inhibitors ChEBI aminophospholipid-transporting ATPase inhibitor ChEBI aminophospholipid-transporting ATPase inhibitors ChEBI flippase inhibitor ChEBI flippase inhibitors ChEBI magnesium-ATPase inhibitor ChEBI magnesium-ATPase inhibitors ChEBI phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor ChEBI phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors ChEBI phospholipid-translocating ATPase inhibitor ChEBI phospholipid-translocating ATPase inhibitors ChEBI phospholipid-transporting ATPase inhibitor ChEBI phospholipid-transporting ATPase inhibitors ChEBI An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44). Wikipedia:Xenobiotic-transporting_ATPase chebi_ontology ATP phosphohydrolase (steroid-exporting) inhibitor ATP phosphohydrolase (steroid-exporting) inhibitors ATP phosphohydrolase (xenobiotic-exporting) inhibitor ATP phosphohydrolase (xenobiotic-exporting) inhibitors EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors EC 3.6.3.44 inhibitor EC 3.6.3.44 inhibitors MDR protein inhibitor MDR protein inhibitors P-glycoprotein inhibitor P-glycoprotein inhibitors PDR protein inhibitor PDR protein inhibitors multidrug-resistance protein inhibitor multidrug-resistance protein inhibitors pleiotropic-drug-resistance protein inhibitor pleiotropic-drug-resistance protein inhibitors steroid-transporting ATPase inhibitor steroid-transporting ATPase inhibitors xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors xenobiotic-transporting ATPase inhibitor xenobiotic-transporting ATPase inhibitors CHEBI:77748 EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor CHEBI:77748 ATP phosphohydrolase (steroid-exporting) inhibitor ChEBI ATP phosphohydrolase (steroid-exporting) inhibitors ChEBI ATP phosphohydrolase (xenobiotic-exporting) inhibitor ChEBI ATP phosphohydrolase (xenobiotic-exporting) inhibitors ChEBI EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors ChEBI EC 3.6.3.44 inhibitor ChEBI EC 3.6.3.44 inhibitors ChEBI MDR protein inhibitor ChEBI MDR protein inhibitors ChEBI P-glycoprotein inhibitor ChEBI P-glycoprotein inhibitors ChEBI PDR protein inhibitor ChEBI PDR protein inhibitors ChEBI multidrug-resistance protein inhibitor ChEBI multidrug-resistance protein inhibitors ChEBI pleiotropic-drug-resistance protein inhibitor ChEBI pleiotropic-drug-resistance protein inhibitors ChEBI steroid-transporting ATPase inhibitor ChEBI steroid-transporting ATPase inhibitors ChEBI xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor ChEBI xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors ChEBI xenobiotic-transporting ATPase inhibitor ChEBI xenobiotic-transporting ATPase inhibitors ChEBI Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains. Wikipedia:Persistant_organic_pollutant chebi_ontology POP POPs persistent organic pollutants CHEBI:77853 persistent organic pollutant CHEBI:77853 POP ChEBI POPs ChEBI persistent organic pollutants ChEBI An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase). Wikipedia:Sterol_14-demethylase chebi_ontology EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors EC 1.14.13.70 inhibitor EC 1.14.13.70 inhibitors cytochrome P450 51 inhibitor cytochrome P450 51 inhibitors lanosterol 14-demethylase inhibitor lanosterol 14-demethylase inhibitors lanosterol 14alpha-demethylase inhibitor lanosterol 14alpha-demethylase inhibitors obtusufoliol 14-demethylase inhibitor obtusufoliol 14-demethylase inhibitors sterol 14-demethylase inhibitor sterol 14-demethylase inhibitors sterol 14alpha-demethylase inhibitor sterol 14alpha-demethylase inhibitors sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors CHEBI:77884 EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor CHEBI:77884 EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors ChEBI EC 1.14.13.70 inhibitor ChEBI EC 1.14.13.70 inhibitors ChEBI cytochrome P450 51 inhibitor ChEBI cytochrome P450 51 inhibitors ChEBI lanosterol 14-demethylase inhibitor ChEBI lanosterol 14-demethylase inhibitors ChEBI lanosterol 14alpha-demethylase inhibitor ChEBI lanosterol 14alpha-demethylase inhibitors ChEBI obtusufoliol 14-demethylase inhibitor ChEBI obtusufoliol 14-demethylase inhibitors ChEBI sterol 14-demethylase inhibitor ChEBI sterol 14-demethylase inhibitors ChEBI sterol 14alpha-demethylase inhibitor ChEBI sterol 14alpha-demethylase inhibitors ChEBI sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor ChEBI sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors ChEBI A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of minocycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). 0 C23H27N3O7 InChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1 DYKFCLLONBREIL-KVUCHLLUSA-N 457.47640 457.18490 CN(C)c1ccc(O)c2C(=O)C3=C(O)[C@@]4(O)[C@@H](C[C@@H]3Cc12)[C@H]([NH+](C)C)C([O-])=C(C(N)=O)C4=O (1S,4aS,11aR,12aS)-3-carbamoyl-10-(dimethylamino)-1-(dimethylazaniumyl)-4a,5,7-trihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate chebi_ontology minocycline CHEBI:77906 minocycline zwitterion CHEBI:77906 (1S,4aS,11aR,12aS)-3-carbamoyl-10-(dimethylamino)-1-(dimethylazaniumyl)-4a,5,7-trihydroxy-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate IUPAC minocycline UniProt A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). 0 C22H24N2O8 InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1 OFVLGDICTFRJMM-WESIUVDSSA-N 444.43460 444.15327 C[NH+](C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1[O-])C(=O)c1c(O)cccc1[C@@]3(C)O (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,5,7,11-tetrahydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate chebi_ontology tetracycline CHEBI:77932 tetracycline zwitterion CHEBI:77932 (1S,4aS,11S,11aS,12aS)-3-carbamoyl-1-(dimethylazaniumyl)-4a,5,7,11-tetrahydroxy-11-methyl-4,6-dioxo-1,4,4a,6,11,11a,12,12a-octahydrotetracen-2-olate IUPAC tetracycline UniProt An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). Wikipedia:Amidase chebi_ontology EC 3.5.1.4 (amidase) inhibitors EC 3.5.1.4 inhibitor EC 3.5.1.4 inhibitors N-acetylaminohydrolase inhibitor N-acetylaminohydrolase inhibitors acylamidase inhibitor acylamidase inhibitors acylamide amidohydrolase inhibitor acylamide amidohydrolase inhibitors amidase (EC 3.5.1.4) inhibitor amidase (EC 3.5.1.4) inhibitors amidase inhibitor amidase inhibitors amidohydrolase inhibitor amidohydrolase inhibitors deaminase inhibitor deaminase inhibitors fatty acylamidase inhibitor fatty acylamidase inhibitors CHEBI:77941 EC 3.5.1.4 (amidase) inhibitor CHEBI:77941 EC 3.5.1.4 (amidase) inhibitors ChEBI EC 3.5.1.4 inhibitor ChEBI EC 3.5.1.4 inhibitors ChEBI N-acetylaminohydrolase inhibitor ChEBI N-acetylaminohydrolase inhibitors ChEBI acylamidase inhibitor ChEBI acylamidase inhibitors ChEBI acylamide amidohydrolase inhibitor ChEBI acylamide amidohydrolase inhibitors ChEBI amidase (EC 3.5.1.4) inhibitor ChEBI amidase (EC 3.5.1.4) inhibitors ChEBI amidase inhibitor ChEBI amidase inhibitors ChEBI amidohydrolase inhibitor ChEBI amidohydrolase inhibitors ChEBI deaminase inhibitor ChEBI deaminase inhibitors ChEBI fatty acylamidase inhibitor ChEBI fatty acylamidase inhibitors ChEBI A peptide anion that is the conjugate base of vancomycin aglycone and the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). -1 C53H51Cl2N8O17 InChI=1S/C53H52Cl2N8O17/c1-19(2)10-29(57-3)47(71)62-42-44(68)21-5-8-33(27(54)12-21)79-35-14-23-15-36(46(35)70)80-34-9-6-22(13-28(34)55)45(69)43-52(76)61-41(53(77)78)26-16-24(64)17-32(66)38(26)25-11-20(4-7-31(25)65)39(49(73)63-43)60-50(74)40(23)59-48(72)30(18-37(56)67)58-51(42)75/h4-9,11-17,19,29-30,39-45,57,64-66,68-70H,10,18H2,1-3H3,(H2,56,67)(H,58,75)(H,59,72)(H,60,74)(H,61,76)(H,62,71)(H,63,73)(H,77,78)/p-1/t29-,30+,39-,40-,41+,42-,43+,44-,45-/m1/s1 JHIKFOISFAQTJQ-YZANBJIASA-M 1142.92200 1141.27547 C[NH2+][C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C([O-])=O)c3[O-])c(Cl)c2 (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylazaniumyl)pentanoyl]amino}-48-oxido-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylate chebi_ontology vancomycin aglycone CHEBI:77981 vancomycin aglycone(1-) CHEBI:77981 (1S,2R,18R,19R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylazaniumyl)pentanoyl]amino}-48-oxido-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylate IUPAC vancomycin aglycone UniProt A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. 0 C19H19N3O5S InChI=1S/C19H19N3O5S/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26)/t13-,14+,17-/m1/s1 UWYHMGVUTGAWSP-JKIFEVAISA-N 401.43600 401.10454 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1ccccc1)C(O)=O Beilstein:1093589 CAS:66-79-5 DrugBank:DB00713 Drug_Central:2006 HMDB:HMDB0014851 KEGG:C07334 KEGG:D08307 LINCS:LSM-6005 PMID:14010809 PMID:20407237 PMID:24295979 PMID:24936596 PMID:29017833 PMID:8566082 Patent:US2996501 Reaxys:1093589 Wikipedia:Oxacillin 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylic acid Oxacillin chebi_ontology (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (5-methyl-3-phenyl-4-isoxazolyl)penicillin 5-methyl-3-phenyl-4-isoxazolyl-penicillin 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid oxazocillin CHEBI:7809 oxacillin CHEBI:7809 Beilstein:1093589 Beilstein CAS:66-79-5 ChemIDplus CAS:66-79-5 KEGG COMPOUND Drug_Central:2006 DrugCentral PMID:14010809 Europe PMC PMID:20407237 Europe PMC PMID:24295979 Europe PMC PMID:24936596 Europe PMC PMID:29017833 Europe PMC PMID:8566082 Europe PMC Reaxys:1093589 Reaxys 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylic acid IUPAC Oxacillin KEGG_COMPOUND (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC (5-methyl-3-phenyl-4-isoxazolyl)penicillin ChemIDplus 5-methyl-3-phenyl-4-isoxazolyl-penicillin ChemIDplus 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ChEBI oxazocillin ChemIDplus Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. -1 C24H47O2 367.62880 367.35761 [O-]C([*])=O chebi_ontology fatty acid 24:0 CHEBI:78128 fatty acid anion 24:0 CHEBI:78128 fatty acid 24:0 UniProt A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. chebi_ontology dietary component dietary components food components CHEBI:78295 food component CHEBI:78295 dietary component ChEBI dietary components ChEBI food components ChEBI Any minor or unwanted substance introduced into the environment that can have undesired effects. chebi_ontology environmental contaminants CHEBI:78298 environmental contaminant CHEBI:78298 environmental contaminants ChEBI An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7). Wikipedia:UDP-N-acetylglucosamine_1-carboxyvinyltransferase chebi_ontology EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors EC 2.5.1.7 inhibitor EC 2.5.1.7 inhibitors MurA transferase inhibitor MurA transferase inhibitors UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors enoylpyruvate transferase inhibitor enoylpyruvate transferase inhibitors phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors pyruvate-UDP-acetylglucosamine transferase inhibitor pyruvate-UDP-acetylglucosamine transferase inhibitors pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors CHEBI:78379 EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor CHEBI:78379 EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors ChEBI EC 2.5.1.7 inhibitor ChEBI EC 2.5.1.7 inhibitors ChEBI MurA transferase inhibitor ChEBI MurA transferase inhibitors ChEBI UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor ChEBI UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors ChEBI UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor ChEBI UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors ChEBI UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor ChEBI UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors ChEBI UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor ChEBI UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors ChEBI enoylpyruvate transferase inhibitor ChEBI enoylpyruvate transferase inhibitors ChEBI phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor ChEBI phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors ChEBI phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor ChEBI phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors ChEBI phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor ChEBI phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors ChEBI phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor ChEBI phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors ChEBI phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor ChEBI phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors ChEBI phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor ChEBI phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors ChEBI phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor ChEBI phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors ChEBI pyruvate-UDP-acetylglucosamine transferase inhibitor ChEBI pyruvate-UDP-acetylglucosamine transferase inhibitors ChEBI pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor ChEBI pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors ChEBI pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor ChEBI pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors ChEBI pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor ChEBI pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors ChEBI A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure. Wikipedia:Refrigerant chebi_ontology refrigerants CHEBI:78433 refrigerant CHEBI:78433 refrigerants ChEBI An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3. 0 C2H4NO2R 74.059 74.02420 [NH3+]C([*])C([O-])=O CHEBI:83409 MetaCyc:Alpha-Amino-Acids chebi_ontology an alpha-amino acid CHEBI:78608 alpha-amino acid zwitterion CHEBI:78608 MetaCyc:Alpha-Amino-Acids SUBMITTER an alpha-amino acid UniProt Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. chebi_ontology carbohydrates and derivatives carbohydrates and their derivatives CHEBI:78616 carbohydrates and carbohydrate derivatives CHEBI:78616 carbohydrates and derivatives ChEBI carbohydrates and their derivatives ChEBI Any metabolite produced by all living cells. chebi_ontology essential metabolite essential metabolites fundamental metabolites CHEBI:78675 fundamental metabolite CHEBI:78675 essential metabolite ChEBI essential metabolites ChEBI fundamental metabolites ChEBI A member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1. 0 C22H18N2 InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H OCAPBUJLXMYKEJ-UHFFFAOYSA-N 310.39170 310.14700 c1cn(cn1)C(c1ccccc1)c1ccc(cc1)-c1ccccc1 LINCS:LSM-5184 1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole chebi_ontology CHEBI:78692 1-[biphenyl-4-yl(phenyl)methyl]imidazole CHEBI:78692 1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole IUPAC A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the R-enantiomer of bifonazole. 0 C22H18N2 InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H/t22-/m1/s1 OCAPBUJLXMYKEJ-JOCHJYFZSA-N 310.39170 310.14700 c1cn(cn1)[C@H](c1ccccc1)c1ccc(cc1)-c1ccccc1 Reaxys:8626154 1-[(R)-biphenyl-4-yl(phenyl)methyl]-1H-imidazole chebi_ontology (-)-bifonazole (R)-(-)-bifonazole CHEBI:78693 (R)-bifonazole CHEBI:78693 Reaxys:8626154 Reaxys 1-[(R)-biphenyl-4-yl(phenyl)methyl]-1H-imidazole IUPAC (-)-bifonazole ChEBI (R)-(-)-bifonazole ChEBI A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the S-enantiomer of bifonazole. 0 C22H18N2 InChI=1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H/t22-/m0/s1 OCAPBUJLXMYKEJ-QFIPXVFZSA-N 310.39170 310.14700 c1cn(cn1)[C@@H](c1ccccc1)c1ccc(cc1)-c1ccccc1 Reaxys:8626153 1-[(S)-biphenyl-4-yl(phenyl)methyl]-1H-imidazole chebi_ontology (+)-bifonazole (S)-(+)-bifonazole CHEBI:78694 (S)-bifonazole CHEBI:78694 Reaxys:8626153 Reaxys 1-[(S)-biphenyl-4-yl(phenyl)methyl]-1H-imidazole IUPAC (+)-bifonazole ChEBI (S)-(+)-bifonazole ChEBI A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. 0 C16H13NO7 InChI=1S/C16H13NO7/c1-5(18)10-7(20)4-9-16(2,14(10)22)12-8(21)3-6(19)11(15(17)23)13(12)24-9/h3-4,19-21H,1-2H3,(H2,17,23)/t16-/m1/s1 GEWLYFZWVLXQME-MRXNPFEDSA-N 331.27690 331.06920 CC(=O)C1=C(O)C=C2Oc3c(c(O)cc(O)c3C(N)=O)[C@]2(C)C1=O CAS:131436-22-1 PMID:15302826 PMID:21814808 PMID:23509154 PMID:8289782 Patent:CN101292039 Patent:EP1914313 Patent:JP2008214336 Patent:KR20080033345 Patent:US2010152467 Patent:WO2007018194 Reaxys:5485233 (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide chebi_ontology CHEBI:78696 cercosporamide CHEBI:78696 CAS:131436-22-1 ChemIDplus PMID:15302826 Europe PMC PMID:21814808 Europe PMC PMID:23509154 Europe PMC PMID:8289782 Europe PMC Reaxys:5485233 Reaxys (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide IUPAC Any organic acid in which both oxygens of a carbamic acid have been replaced by sulfur. 0 CHNS2R2 91.158 90.95504 SC(=S)N([*])[*] chebi_ontology dithiocarbamic acid CHEBI:78787 dithiocarbamic acids CHEBI:78787 dithiocarbamic acid ChEBI Any organic molecular entity that contains at least one C=C bond. chebi_ontology olefinic compounds CHEBI:78840 olefinic compound CHEBI:78840 olefinic compounds ChEBI A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond. chebi_ontology 2,3-unsaturated monocarboxylic acid 2,3-unsaturated monocarboxylic acids alpha,beta-unsaturated monocarboxylic acids CHEBI:79020 alpha,beta-unsaturated monocarboxylic acid CHEBI:79020 2,3-unsaturated monocarboxylic acid ChEBI 2,3-unsaturated monocarboxylic acids ChEBI alpha,beta-unsaturated monocarboxylic acids ChEBI An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24). CHEBI:75997 Wikipedia:MEK_inhibitor Wikipedia:Mitogen-activated_protein_kinase chebi_ontology ATP:protein phosphotransferase (MAPKK-activated) inhibitor ATP:protein phosphotransferase (MAPKK-activated) inhibitors Dp38 inhibitor Dp38 inhibitors EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors EC 2.7.11.24 inhibitor EC 2.7.11.24 inhibitors ERK inhibitor ERK inhibitors ERK1 inhibitor ERK1 inhibitors ERK2 inhibitor ERK2 inhibitors JNK inhibitor JNK inhibitors JNK3alpha1 inhibitor JNK3alpha1 inhibitors LeMPK3 inhibitor LeMPK3 inhibitors MAP kinase inhibitor MAP kinase inhibitors MAP-2 kinase inhibitor MAP-2 kinase inhibitors MAPK inhibitor MAPK inhibitors MBP kinase I inhibitor MBP kinase I inhibitors MBP kinase II inhibitor MBP kinase II inhibitors MEK inhibitor MEK inhibitors PMK-1 inhibitor PMK-1 inhibitors PMK-2 inhibitor PMK-2 inhibitors PMK-3 inhibitor PMK-3 inhibitors SAPK inhibitor SAPK inhibitors STK26 inhibitor STK26 inhibitors c-Jun N-terminal kinase inhibitor c-Jun N-terminal kinase inhibitors extracellular signal-regulated kinase inhibitor extracellular signal-regulated kinase inhibitors microtubule-associated protein 2 kinase inhibitor microtubule-associated protein 2 kinase inhibitors microtubule-associated protein kinase inhibitor microtubule-associated protein kinase inhibitors mitogen-activated protein kinase (EC 2.7.11.24) inhibitor mitogen-activated protein kinase (EC 2.7.11.24) inhibitors mitogen-activated protein kinase inhibitor mitogen-activated protein kinase inhibitors myelin basic protein kinase inhibitor myelin basic protein kinase inhibitors p38-2 inhibitor p38-2 inhibitors p38delta inhibitor p38delta inhibitors p42 mitogen-activated protein kinase inhibitor p42 mitogen-activated protein kinase inhibitors p42(mapk) inhibitor p42(mapk) inhibitors p44mpk inhibitor p44mpk inhibitors pp42 inhibitor pp42 inhibitors pp44(mapk) inhibitor pp44(mapk) inhibitors stress-activated protein kinase inhibitor stress-activated protein kinase inhibitors CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor CHEBI:79091 ATP:protein phosphotransferase (MAPKK-activated) inhibitor ChEBI ATP:protein phosphotransferase (MAPKK-activated) inhibitors ChEBI Dp38 inhibitor ChEBI Dp38 inhibitors ChEBI EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors ChEBI EC 2.7.11.24 inhibitor ChEBI EC 2.7.11.24 inhibitors ChEBI ERK inhibitor ChEBI ERK inhibitors ChEBI ERK1 inhibitor ChEBI ERK1 inhibitors ChEBI ERK2 inhibitor ChEBI ERK2 inhibitors ChEBI JNK inhibitor ChEBI JNK inhibitors ChEBI JNK3alpha1 inhibitor ChEBI JNK3alpha1 inhibitors ChEBI LeMPK3 inhibitor ChEBI LeMPK3 inhibitors ChEBI MAP kinase inhibitor ChEBI MAP kinase inhibitors ChEBI MAP-2 kinase inhibitor ChEBI MAP-2 kinase inhibitors ChEBI MAPK inhibitor ChEBI MAPK inhibitors ChEBI MBP kinase I inhibitor ChEBI MBP kinase I inhibitors ChEBI MBP kinase II inhibitor ChEBI MBP kinase II inhibitors ChEBI MEK inhibitor ChEBI MEK inhibitors ChEBI PMK-1 inhibitor ChEBI PMK-1 inhibitors ChEBI PMK-2 inhibitor ChEBI PMK-2 inhibitors ChEBI PMK-3 inhibitor ChEBI PMK-3 inhibitors ChEBI SAPK inhibitor ChEBI SAPK inhibitors ChEBI STK26 inhibitor ChEBI STK26 inhibitors ChEBI c-Jun N-terminal kinase inhibitor ChEBI c-Jun N-terminal kinase inhibitors ChEBI extracellular signal-regulated kinase inhibitor ChEBI extracellular signal-regulated kinase inhibitors ChEBI microtubule-associated protein 2 kinase inhibitor ChEBI microtubule-associated protein 2 kinase inhibitors ChEBI microtubule-associated protein kinase inhibitor ChEBI microtubule-associated protein kinase inhibitors ChEBI mitogen-activated protein kinase (EC 2.7.11.24) inhibitor ChEBI mitogen-activated protein kinase (EC 2.7.11.24) inhibitors ChEBI mitogen-activated protein kinase inhibitor ChEBI mitogen-activated protein kinase inhibitors ChEBI myelin basic protein kinase inhibitor ChEBI myelin basic protein kinase inhibitors ChEBI p38-2 inhibitor ChEBI p38-2 inhibitors ChEBI p38delta inhibitor ChEBI p38delta inhibitors ChEBI p42 mitogen-activated protein kinase inhibitor ChEBI p42 mitogen-activated protein kinase inhibitors ChEBI p42(mapk) inhibitor ChEBI p42(mapk) inhibitors ChEBI p44mpk inhibitor ChEBI p44mpk inhibitors ChEBI pp42 inhibitor ChEBI pp42 inhibitors ChEBI pp44(mapk) inhibitor ChEBI pp44(mapk) inhibitors ChEBI stress-activated protein kinase inhibitor ChEBI stress-activated protein kinase inhibitors ChEBI An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*). chebi_ontology EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors EC 1.11.2.* inhibitor EC 1.11.2.* inhibitors CHEBI:79092 EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor CHEBI:79092 EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors ChEBI EC 1.11.2.* inhibitor ChEBI EC 1.11.2.* inhibitors ChEBI An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2). Wikipedia:Myeloperoxidase chebi_ontology EC 1.11.2.2 (myeloperoxidase) inhibitors EC 1.11.2.2 inhibitor EC 1.11.2.2 inhibitors MPO inhibitor MPO inhibitors chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors myeloperoxidase (EC 1.11.2.2) inhibitor myeloperoxidase (EC 1.11.2.2) inhibitors myeloperoxidase inhibitor myeloperoxidase inhibitors verdoperoxidase inhibitor verdoperoxidase inhibitors CHEBI:79093 EC 1.11.2.2 (myeloperoxidase) inhibitor CHEBI:79093 EC 1.11.2.2 (myeloperoxidase) inhibitors ChEBI EC 1.11.2.2 inhibitor ChEBI EC 1.11.2.2 inhibitors ChEBI MPO inhibitor ChEBI MPO inhibitors ChEBI chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor ChEBI chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors ChEBI myeloperoxidase (EC 1.11.2.2) inhibitor ChEBI myeloperoxidase (EC 1.11.2.2) inhibitors ChEBI myeloperoxidase inhibitor ChEBI myeloperoxidase inhibitors ChEBI verdoperoxidase inhibitor ChEBI verdoperoxidase inhibitors ChEBI Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire. Wikipedia:Flame_retardant chebi_ontology flame retardants CHEBI:79314 flame retardant CHEBI:79314 flame retardants ChEBI An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. 0 C23H45N5O14 InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 UOZODPSAJZTQNH-LSWIJEOBSA-N 615.62850 615.29630 NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O CHEBI:44703 CAS:7542-37-2 DrugBank:DB01421 Drug_Central:2067 KEGG:C00832 KEGG:D07467 PDBeChem:PAR PMID:18447603 PMID:18947845 PMID:8036682 Patent:US2895876 Patent:US2916485 Reaxys:72285 (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside PAROMOMYCIN Paromomycin chebi_ontology (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside Aminosidin Catenulin Hydroxymycin Monomycin A Neomycin E Paromomycin I R 400 R-400 Zygomycin A1 aminosidine crestomycin estomycin hydroxymycin neomycin E paromomicina paromomycin paromomycine paromomycinum paucimycin paucimycinum CHEBI:7934 paromomycin CHEBI:7934 CAS:7542-37-2 ChemIDplus CAS:7542-37-2 KEGG COMPOUND Drug_Central:2067 DrugCentral PMID:18447603 Europe PMC PMID:18947845 Europe PMC PMID:8036682 Europe PMC Reaxys:72285 Reaxys (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside IUPAC PAROMOMYCIN PDBeChem Paromomycin KEGG_COMPOUND (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside PDBeChem Aminosidin KEGG_COMPOUND Catenulin KEGG_COMPOUND Hydroxymycin KEGG_COMPOUND Monomycin A KEGG_COMPOUND Neomycin E KEGG_COMPOUND Paromomycin I KEGG_COMPOUND R 400 ChemIDplus R-400 ChEBI Zygomycin A1 KEGG_COMPOUND aminosidine ChemIDplus crestomycin ChemIDplus estomycin ChemIDplus hydroxymycin ChemIDplus neomycin E ChemIDplus paromomicina ChemIDplus paromomycin WHO_MedNet paromomycine ChemIDplus paromomycinum ChemIDplus paucimycin ChemIDplus paucimycinum ChemIDplus Any inorganic anion with a valency of three. chebi_ontology trivalent inorganic anions CHEBI:79387 trivalent inorganic anion CHEBI:79387 trivalent inorganic anions ChEBI Any inorganic anion with a valency of two. chebi_ontology divalent inorganic anions CHEBI:79388 divalent inorganic anion CHEBI:79388 divalent inorganic anions ChEBI Any inorganic anion with a valency of one. chebi_ontology monovalent inorganic anions CHEBI:79389 monovalent inorganic anion CHEBI:79389 monovalent inorganic anions ChEBI A diastereoisomeric mixture composed of the enantiomeric pair (2R,3S)- and (2S,3R)-cyproconazole in ratio 1:1 with the enantiomeric pair (2R,3R)- and (2S,3S)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases. CAS:94361-06-5 KEGG:C18456 PMID:23708404 PMID:24691702 PMID:25182419 Pesticides:cyproconazole Reaxys:8324780 rac-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology alpha-(4-chlorophenyl)-alpha-(1-cyclopropylethyl)-1N-1,2,4-triazole-1-ethanol CHEBI:81758 cyproconazole CHEBI:81758 CAS:94361-06-5 ChemIDplus CAS:94361-06-5 KEGG COMPOUND PMID:23708404 Europe PMC PMID:24691702 Europe PMC PMID:25182419 Europe PMC Pesticides:cyproconazole Alan Wood's Pesticides Reaxys:8324780 Reaxys rac-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC alpha-(4-chlorophenyl)-alpha-(1-cyclopropylethyl)-1N-1,2,4-triazole-1-ethanol Alan_Wood's_Pesticides A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms. 0 C19H17Cl2N3O3 InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3 BQYJATMQXGBDHF-UHFFFAOYSA-N 406.26300 405.06470 CC1COC(Cn2cncn2)(O1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl CAS:119446-68-3 KEGG:C18459 PMID:24405376 PMID:25172726 PMID:25306325 PPDB:230 Pesticides:difenoconazole Reaxys:9073356 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole chebi_ontology CHEBI:81760 difenoconazole CHEBI:81760 CAS:119446-68-3 ChemIDplus CAS:119446-68-3 KEGG COMPOUND CAS:119446-68-3 NIST Chemistry WebBook PMID:24405376 Europe PMC PMID:25172726 Europe PMC PMID:25306325 Europe PMC Pesticides:difenoconazole Alan Wood's Pesticides Reaxys:9073356 Reaxys 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole IUPAC A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria. 0 C12H6F2N2O2 InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H MUJOIMFVNIBMKC-UHFFFAOYSA-N 248.185 248.03973 C1=CC=C2C(=C1C3=CNC=C3C#N)OC(O2)(F)F CAS:131341-86-1 KEGG:C18462 PMID:23052036 PMID:23256745 PMID:23436777 PMID:23799251 PMID:24423402 PMID:24598029 PMID:24635026 PPDB:330 Pesticides:fludioxonil Reaxys:8393936 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile chebi_ontology CHEBI:81763 fludioxonil CHEBI:81763 CAS:131341-86-1 ChemIDplus CAS:131341-86-1 KEGG COMPOUND CAS:131341-86-1 NIST Chemistry WebBook PMID:23052036 Europe PMC PMID:23256745 Europe PMC PMID:23436777 Europe PMC PMID:23799251 Europe PMC PMID:24423402 Europe PMC PMID:24598029 Europe PMC PMID:24635026 Europe PMC Pesticides:fludioxonil Alan Wood's Pesticides Reaxys:8393936 Reaxys 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile IUPAC A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops. CHEBI:83566 CAS:107534-96-3 KEGG:C18489 PMID:24200952 PMID:24522828 PMID:24920897 PMID:25300182 Pesticides:tebuconazole Reaxys:6686475 Wikipedia:Tebuconazole rac-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol chebi_ontology (RS)-1-p-chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Ethyltrianol Fenetrazole Terbuconazole CHEBI:81781 tebuconazole CHEBI:81781 CAS:107534-96-3 ChemIDplus CAS:107534-96-3 KEGG COMPOUND PMID:24200952 Europe PMC PMID:24522828 Europe PMC PMID:24920897 Europe PMC PMID:25300182 Europe PMC Pesticides:tebuconazole Alan Wood's Pesticides Reaxys:6686475 Reaxys rac-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol IUPAC (RS)-1-p-chlorophenyl-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Alan_Wood's_Pesticides Ethyltrianol ChemIDplus Fenetrazole ChemIDplus Terbuconazole ChemIDplus A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union. 0 C9H7N3S InChI=1S/C9H7N3S/c1-6-3-2-4-7-8(6)12-5-10-11-9(12)13-7/h2-5H,1H3 DQJCHOQLCLEDLL-UHFFFAOYSA-N 189.23700 189.03607 Cc1cccc2sc3nncn3c12 CAS:41814-78-2 HMDB:HMDB0031809 KEGG:C18492 PDBeChem:BEA PMID:10888518 PMID:15996714 PMID:18488130 PMID:19062069 PMID:22933369 PMID:23507498 PMID:23973553 PMID:25335466 PPDB:660 Pesticides:tricyclazole Reaxys:980261 5-methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazole chebi_ontology 5-methyl-1,2,4-triazolo[3,4-b]benzothiazole 5-methyl-striazolo-[3,4-b]benzothiazole Blas-T Blascide Pilarblas Sivic Tizole Trizole CHEBI:81783 tricyclazole CHEBI:81783 CAS:41814-78-2 Alan Wood's Pesticides CAS:41814-78-2 ChemIDplus CAS:41814-78-2 KEGG COMPOUND CAS:41814-78-2 NIST Chemistry WebBook PMID:10888518 Europe PMC PMID:15996714 Europe PMC PMID:18488130 Europe PMC PMID:19062069 Europe PMC PMID:22933369 Europe PMC PMID:23507498 Europe PMC PMID:23973553 Europe PMC PMID:25335466 Europe PMC Pesticides:tricyclazole Alan Wood's Pesticides Reaxys:980261 Reaxys 5-methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazole IUPAC 5-methyl-1,2,4-triazolo[3,4-b]benzothiazole Alan_Wood's_Pesticides 5-methyl-striazolo-[3,4-b]benzothiazole ChEBI Blas-T ChemIDplus Blascide NIST_Chemistry_WebBook Pilarblas ChemIDplus Sivic NIST_Chemistry_WebBook Tizole ChemIDplus Trizole ChemIDplus A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals. 0 C18H12Cl2N2O InChI=1S/C18H12Cl2N2O/c19-13-9-7-12(8-10-13)14-4-1-2-6-16(14)22-18(23)15-5-3-11-21-17(15)20/h1-11H,(H,22,23) WYEMLYFITZORAB-UHFFFAOYSA-N 343.20700 342.03267 Clc1ccc(cc1)-c1ccccc1NC(=O)c1cccnc1Cl CAS:188425-85-6 KEGG:C18547 PMID:24380616 PMID:24711278 PMID:24893153 PMID:24901961 PMID:24936710 PPDB:86 Pesticides:boscalid Reaxys:10092464 2-chloro-N-(4'-chlorobiphenyl-2-yl)nicotinamide chebi_ontology 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-3-pyridinecarboxamide 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)pyridine-3-carboxamide CHEBI:81822 boscalid CHEBI:81822 CAS:188425-85-6 ChemIDplus CAS:188425-85-6 KEGG COMPOUND PMID:24380616 Europe PMC PMID:24711278 Europe PMC PMID:24893153 Europe PMC PMID:24901961 Europe PMC PMID:24936710 Europe PMC Pesticides:boscalid Alan Wood's Pesticides Reaxys:10092464 Reaxys 2-chloro-N-(4'-chlorobiphenyl-2-yl)nicotinamide IUPAC 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-3-pyridinecarboxamide Alan_Wood's_Pesticides 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)pyridine-3-carboxamide Alan_Wood's_Pesticides An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol. 0 C14H17Cl2NO2 InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19) VDLGAVXLJYLFDH-UHFFFAOYSA-N 302.19600 301.06363 CC1(CCCCC1)C(=O)Nc1ccc(O)c(Cl)c1Cl AGR:IND500627165 CAS:126833-17-8 KEGG:C18593 PMID:17390774 PMID:19285148 PMID:22045588 PMID:23052036 PMID:23139232 PPDB:298 Patent:EP339418 Patent:US5059623 Pesticides:fenhexamid Reaxys:8996658 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide chebi_ontology 2',3'-dichloro-4'-hydroxy-1-methylcyclohexanecarboxanilide KBR 2738 KBR-2738 N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Teldor fenhexamide CHEBI:81853 fenhexamid CHEBI:81853 AGR:IND500627165 Europe PMC CAS:126833-17-8 ChemIDplus CAS:126833-17-8 KEGG COMPOUND PMID:17390774 Europe PMC PMID:19285148 Europe PMC PMID:22045588 Europe PMC PMID:23052036 Europe PMC PMID:23139232 Europe PMC Pesticides:fenhexamid Alan Wood's Pesticides Reaxys:8996658 Reaxys N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide IUPAC 2',3'-dichloro-4'-hydroxy-1-methylcyclohexanecarboxanilide ChEBI KBR 2738 ChemIDplus KBR-2738 ChEBI N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide Alan_Wood's_Pesticides Teldor ChemIDplus fenhexamide ChEBI A racemate comprising equimolar amounts of (R)- and (S)-diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts. 0 C15H17Cl2N3O 326.220 325.07487 CAS:83657-24-3 KEGG:C18720 PMID:18973222 PMID:22579069 PMID:22667094 PMID:23056532 PMID:24009183 PMID:24009189 PMID:24211030 PPDB:247 Pesticides:diniconazole Reaxys:9202976 rac-(1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol chebi_ontology (+-)-diniconazole (E)-1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol (RS)-diniconazole (betaE)-beta-[(2,4-dichlorophenyl)methylene]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol 1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol rac-diniconazole racemic diniconazole CHEBI:81913 diniconazole CHEBI:81913 CAS:83657-24-3 ChemIDplus CAS:83657-24-3 KEGG COMPOUND CAS:83657-24-3 NIST Chemistry WebBook PMID:18973222 Europe PMC PMID:22579069 Europe PMC PMID:22667094 Europe PMC PMID:23056532 Europe PMC PMID:24009183 Europe PMC PMID:24009189 Europe PMC PMID:24211030 Europe PMC Pesticides:diniconazole Alan Wood's Pesticides Reaxys:9202976 Reaxys rac-(1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol IUPAC (+-)-diniconazole ChEBI (E)-1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol ChemIDplus (RS)-diniconazole ChEBI (betaE)-beta-[(2,4-dichlorophenyl)methylene]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol Alan_Wood's_Pesticides 1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol NIST_Chemistry_WebBook rac-diniconazole ChEBI racemic diniconazole ChEBI A racemate comprising equimolar amounts of (R)- and (S)-fenpropidin. A systemic fungicide, it is used for the control of foliar diseases in cereals and sugar beet. 0 C19H31N 273.45610 273.24565 AGR:IND91056129 CAS:67306-00-7 KEGG:C18726 PMID:22078112 PMID:2591378 PPDB:307 Pesticides:fenpropidin Reaxys:1245248 rac-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine chebi_ontology (+-)-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine (RS)-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine Patrol Ro 12-3049 Ro-12-3049 fenpropidine CHEBI:81917 fenpropidin CHEBI:81917 AGR:IND91056129 Europe PMC CAS:67306-00-7 ChemIDplus CAS:67306-00-7 KEGG COMPOUND CAS:67306-00-7 NIST Chemistry WebBook PMID:22078112 Europe PMC PMID:2591378 Europe PMC Pesticides:fenpropidin Alan Wood's Pesticides Reaxys:1245248 Reaxys rac-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine IUPAC (+-)-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine ChEBI (RS)-1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine ChEBI Patrol ChemIDplus Ro 12-3049 ChemIDplus Ro-12-3049 NIST_Chemistry_WebBook fenpropidine ChemIDplus A racemate comprising an equimolar mixture of (R)- and (S)-flutriafol. A systemic fungicide, it is used to control fungal diseases in cereal crops. 0 C16H13F2N3O 301.29070 301.10267 CAS:76674-21-0 KEGG:C18734 PMID:18178235 PMID:20533452 PMID:21740052 PMID:22885544 PMID:22983725 PMID:23208429 PMID:24611465 PMID:25300182 PMID:25376483 Patent:EP15756 Pesticides:76674-21-0 Pesticides:flutriafol Reaxys:7141682 rac-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol chebi_ontology (+-)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol (+-)-flutriafol (RS)-2,4'-difluoro-alpha-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol PP 450 R 152450 alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol rac flutriafol rac-(1R)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol CHEBI:81923 flutriafol CHEBI:81923 CAS:76674-21-0 ChemIDplus CAS:76674-21-0 KEGG COMPOUND CAS:76674-21-0 NIST Chemistry WebBook PMID:18178235 Europe PMC PMID:20533452 Europe PMC PMID:21740052 Europe PMC PMID:22885544 Europe PMC PMID:22983725 Europe PMC PMID:23208429 Europe PMC PMID:24611465 Europe PMC PMID:25300182 Europe PMC PMID:25376483 Europe PMC Pesticides:76674-21-0 Alan Wood's Pesticides Pesticides:flutriafol Alan Wood's Pesticides Reaxys:7141682 Reaxys rac-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol IUPAC (+-)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol ChEBI (+-)-flutriafol ChEBI (RS)-2,4'-difluoro-alpha-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol Alan_Wood's_Pesticides PP 450 NIST_Chemistry_WebBook R 152450 NIST_Chemistry_WebBook alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol Alan_Wood's_Pesticides rac flutriafol ChEBI rac-(1R)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol Alan_Wood's_Pesticides A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group. 0 C23H27N5O7S InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1 IVBHGBMCVLDMKU-GXNBUGAJSA-N 517.55500 517.16312 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)c1ccccc1)C(O)=O CHEBI:472443 CHEBI:475140 CHEBI:505944 Beilstein:6081140 CAS:61477-96-1 DrugBank:DB00319 Drug_Central:2187 KEGG:C14034 KEGG:D08380 LINCS:LSM-5924 PMID:1701026 PMID:17116662 PMID:17158942 PMID:17851079 PMID:25998949 PMID:29017833 PMID:29148816 PMID:7486906 Patent:DE2519400 Patent:US4087424 Reaxys:6081140 Wikipedia:Piperacillin 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid Piperacillin chebi_ontology (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Piperacillin anhydrous piperacillin CHEBI:8232 piperacillin CHEBI:8232 Beilstein:6081140 Beilstein CAS:61477-96-1 ChemIDplus CAS:61477-96-1 KEGG COMPOUND Drug_Central:2187 DrugCentral PMID:1701026 Europe PMC PMID:17116662 ChEMBL PMID:17158942 ChEMBL PMID:17851079 ChEMBL PMID:25998949 Europe PMC PMID:29017833 Europe PMC PMID:29148816 Europe PMC PMID:7486906 Europe PMC Reaxys:6081140 Reaxys 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC Piperacillin KEGG_COMPOUND (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC Piperacillin anhydrous KEGG_COMPOUND piperacillin KEGG_DRUG 0 C22H34O5 InChI=1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13?,14-,16+,18-,19-,20+,21-,22-/m0/s1 ZRZNJUXESFHSIO-ZXVYJXQESA-N 378.503 378.24062 CC1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO CAS:125-65-5 KEGG:C09169 KNApSAcK:C00003473 Pleuromutilin chebi_ontology CHEBI:8269 Pleuromutilin CHEBI:8269 CAS:125-65-5 KEGG COMPOUND Pleuromutilin KEGG_COMPOUND A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively. 0 C11H8O3 InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3 VCMMXZQDRFWYSE-UHFFFAOYSA-N 188.182 188.04734 CC1=CC(=O)C2=C(O)C=CC=C2C1=O Beilstein:1870475 CAS:481-42-5 Gmelin:959690 KEGG:C10387 KNApSAcK:C00002852 LINCS:LSM-37061 MetaCyc:CPD-4461 PDBeChem:90R PMID:14727919 PMID:14762525 PMID:16078700 PMID:16624823 PMID:18974148 PMID:19748668 PMID:20858709 PMID:21064184 PMID:21559086 PMID:21658027 PMID:21741707 Patent:CN1473468 Patent:IN183682 Patent:IN191797 Reaxys:1870475 Wikipedia:Plumbagin 5-hydroxy-2-methylnaphthalene-1,4-dione Plumbagin chebi_ontology 2-methyl-5-hydroxy-1,4-naphthoquinone 2-methyljuglone 5-hydroxy-2-methyl-1,4-naphthalenedione 5-hydroxy-2-methyl-1,4-naphthoquinone plumbaein plumbagine plumbagone CHEBI:8273 plumbagin CHEBI:8273 Beilstein:1870475 ChemIDplus CAS:481-42-5 ChemIDplus CAS:481-42-5 KEGG COMPOUND Gmelin:959690 Gmelin PMID:14727919 Europe PMC PMID:14762525 Europe PMC PMID:16078700 Europe PMC PMID:16624823 Europe PMC PMID:18974148 Europe PMC PMID:19748668 Europe PMC PMID:20858709 Europe PMC PMID:21064184 Europe PMC PMID:21559086 Europe PMC PMID:21658027 Europe PMC PMID:21741707 Europe PMC Reaxys:1870475 Reaxys 5-hydroxy-2-methylnaphthalene-1,4-dione IUPAC Plumbagin KEGG_COMPOUND 2-methyl-5-hydroxy-1,4-naphthoquinone ChemIDplus 2-methyljuglone ChEBI 5-hydroxy-2-methyl-1,4-naphthalenedione ChemIDplus 5-hydroxy-2-methyl-1,4-naphthoquinone ChEBI plumbaein ChEBI plumbagine MetaCyc plumbagone ChEBI An antagonist that binds to and deactivates glucocorticoid receptors. chebi_ontology glucocorticoid receptor antagonists CHEBI:82891 glucocorticoid receptor antagonist CHEBI:82891 glucocorticoid receptor antagonists ChEBI A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group. 0 C18H14Cl4N2O InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2 BYBLEWFAAKGYCD-UHFFFAOYSA-N 416.12900 413.98602 Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole chebi_ontology CHEBI:82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole CHEBI:82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole IUPAC A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has R configuration. 0 C18H14Cl4N2O InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m0/s1 BYBLEWFAAKGYCD-SFHVURJKSA-N 416.12900 413.98602 Clc1ccc(CO[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 Reaxys:9651217 (R)-miconazole 1-[(2R)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole chebi_ontology CHEBI:82894 (R)-miconazole CHEBI:82894 Reaxys:9651217 Reaxys (R)-miconazole UniProt 1-[(2R)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole IUPAC A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has S) configuration. 0 C18H14Cl4N2O InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/t18-/m1/s1 BYBLEWFAAKGYCD-GOSISDBHSA-N 416.12900 413.98602 Clc1ccc(CO[C@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 Reaxys:9651216 (S)-miconazole 1-[(2S)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole chebi_ontology CHEBI:82897 (S)-miconazole CHEBI:82897 Reaxys:9651216 Reaxys (S)-miconazole UniProt 1-[(2S)-2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole IUPAC An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. chebi_ontology crustacean metabolites CHEBI:83039 crustacean metabolite CHEBI:83039 crustacean metabolites ChEBI A Daphnia metabolite produced by the species Daphnia magna. chebi_ontology Daphnia magna metabolites CHEBI:83056 Daphnia magna metabolite CHEBI:83056 Daphnia magna metabolites ChEBI A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia Wikipedia:Daphnia chebi_ontology Daphnia metabolites CHEBI:83057 Daphnia metabolite CHEBI:83057 Daphnia metabolites ChEBI Any salt derived from a member of the class of dithiocarbamic acids by the formal replacement of the hydrogen of the dithiocarboxy group by a metal. chebi_ontology dithiocarbamate salts CHEBI:83060 dithiocarbamate salt CHEBI:83060 dithiocarbamate salts ChEBI An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1. Wikipedia:Succinate_dehydrogenase chebi_ontology EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors EC 1.3.5.1 inhibitor EC 1.3.5.1 inhibitors SDH inhibitor SDH inhibitors complex II inhibitor complex II inhibitors succinate dehydrogenase (ubiquinone) inhibitor succinate dehydrogenase (ubiquinone) inhibitors succinate dehydrogenase complex inhibitor succinate dehydrogenase complex inhibitors succinate dehydrogenase inhibitor succinate dehydrogenase inhibitors succinate:quinone oxidoreductase inhibitor succinate:quinone oxidoreductase inhibitors succinate:ubiquinone oxidoreductase inhibitor succinate:ubiquinone oxidoreductase inhibitors succinic dehydrogenase inhibitor succinic dehydrogenase inhibitors CHEBI:83072 EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor CHEBI:83072 EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors ChEBI EC 1.3.5.1 inhibitor ChEBI EC 1.3.5.1 inhibitors ChEBI SDH inhibitor ChEBI SDH inhibitors ChEBI complex II inhibitor ChEBI complex II inhibitors ChEBI succinate dehydrogenase (ubiquinone) inhibitor ChEBI succinate dehydrogenase (ubiquinone) inhibitors ChEBI succinate dehydrogenase complex inhibitor ChEBI succinate dehydrogenase complex inhibitors ChEBI succinate dehydrogenase inhibitor ChEBI succinate dehydrogenase inhibitors ChEBI succinate:quinone oxidoreductase inhibitor ChEBI succinate:quinone oxidoreductase inhibitors ChEBI succinate:ubiquinone oxidoreductase inhibitor ChEBI succinate:ubiquinone oxidoreductase inhibitors ChEBI succinic dehydrogenase inhibitor ChEBI succinic dehydrogenase inhibitors ChEBI A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus. 0 C56H98N16O13 InChI=1S/C56H98N16O13/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80)/t32-,33-,34-,36+,37+,38+,39+,40+,41+,42+,43-,45+,46+/m1/s1 WQVJHHACXVLGBL-GOVYWFKWSA-N 1203.47670 1202.74993 CC[C@@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O Beilstein:8609638 CAS:4135-11-9 PMID:13058849 PMID:14212410 PMID:1650428 PMID:26803416 Reaxys:9838039 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine} polymyxin B1 chebi_ontology Polymyxin B(1) polymycin B CHEBI:8309 polymyxin B1 CHEBI:8309 Beilstein:8609638 Beilstein CAS:4135-11-9 ChemIDplus PMID:13058849 Europe PMC PMID:14212410 Europe PMC PMID:1650428 Europe PMC PMID:26803416 Europe PMC Reaxys:9838039 Reaxys 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine} IUPAC polymyxin B1 ChEBI Polymyxin B(1) ChEBI polymycin B ChEBI A Daphnia metabolite produced by the species Daphnia tenebrosa. chebi_ontology Daphnia tenebrosa metabolites CHEBI:83146 Daphnia tenebrosa metabolite CHEBI:83146 Daphnia tenebrosa metabolites ChEBI A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group. 0 C19H31N InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3 MGNFYQILYYYUBS-UHFFFAOYSA-N 273.45610 273.24565 CC(CN1CCCCC1)Cc1ccc(cc1)C(C)(C)C 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine chebi_ontology 1-(3-(4-(1,1-dimethylethyl)phenyl)-2-methylpropyl)piperidine CHEBI:83291 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine CHEBI:83291 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine IUPAC 1-(3-(4-(1,1-dimethylethyl)phenyl)-2-methylpropyl)piperidine ChemIDplus A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has R configuration. 0 C19H31N InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3/t16-/m1/s1 MGNFYQILYYYUBS-MRXNPFEDSA-N 273.45610 273.24565 C[C@@H](CN1CCCCC1)Cc1ccc(cc1)C(C)(C)C 1-[(2R)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine chebi_ontology CHEBI:83293 (R)-fenpropidin CHEBI:83293 1-[(2R)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine IUPAC A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has S configuration. 0 C19H31N InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3/t16-/m0/s1 MGNFYQILYYYUBS-INIZCTEOSA-N 273.45610 273.24565 C[C@H](CN1CCCCC1)Cc1ccc(cc1)C(C)(C)C 1-[(2S)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine chebi_ontology CHEBI:83294 (S)-fenpropidin CHEBI:83294 1-[(2S)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine IUPAC A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a dodecyl group. The configuration at positions 2 and 6 is unknown or unspecified. 0 C18H37NO InChI=1S/C18H37NO/c1-4-5-6-7-8-9-10-11-12-13-14-19-15-17(2)20-18(3)16-19/h17-18H,4-16H2,1-3H3 SBUKOHLFHYSZNG-UHFFFAOYSA-N 283.49250 283.28751 CCCCCCCCCCCCN1CC(C)OC(C)C1 CHEBI:83369 CAS:1704-28-5 PPDB:1128 Reaxys:123296 (2Xi,6Xi)-2,6-dimethyl-4-dodecylmorpholine 4-dodecyl-2,6-dimethylmorpholine chebi_ontology 2,6-dimethyl-4-dodecylmorpholine N-dodecyl-2,6-dimethylmorpholine CHEBI:83297 4-dodecyl-2,6-dimethylmorpholine CHEBI:83297 CAS:1704-28-5 ChemIDplus Reaxys:123296 Reaxys (2Xi,6Xi)-2,6-dimethyl-4-dodecylmorpholine IUPAC 4-dodecyl-2,6-dimethylmorpholine IUPAC 2,6-dimethyl-4-dodecylmorpholine ChemIDplus N-dodecyl-2,6-dimethylmorpholine ChEBI An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72). Wikipedia:Methylsterol_monooxygenase chebi_ontology 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors 4-methylsterol oxidase inhibitor 4-methylsterol oxidase inhibitors EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors EC 1.14.13.72 inhibitor EC 1.14.13.72 inhibitors methylsterol hydroxylase inhibitor methylsterol hydroxylase inhibitors methylsterol monooxygenase (EC 1.14.13.72) inhibitor methylsterol monooxygenase (EC 1.14.13.72) inhibitors methylsterol monooxygenase inhibitor methylsterol monooxygenase inhibitors CHEBI:83316 EC 1.14.13.72 (methylsterol monooxygenase) inhibitor CHEBI:83316 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor ChEBI 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors ChEBI 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor ChEBI 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors ChEBI 4-methylsterol oxidase inhibitor ChEBI 4-methylsterol oxidase inhibitors ChEBI EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors ChEBI EC 1.14.13.72 inhibitor ChEBI EC 1.14.13.72 inhibitors ChEBI methylsterol hydroxylase inhibitor ChEBI methylsterol hydroxylase inhibitors ChEBI methylsterol monooxygenase (EC 1.14.13.72) inhibitor ChEBI methylsterol monooxygenase (EC 1.14.13.72) inhibitors ChEBI methylsterol monooxygenase inhibitor ChEBI methylsterol monooxygenase inhibitors ChEBI Any compound that inhibits the biosynthesis of any sterol. chebi_ontology sterol biosynthesis inhibitors CHEBI:83317 sterol biosynthesis inhibitor CHEBI:83317 sterol biosynthesis inhibitors ChEBI An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70). Wikipedia:Delta14-sterol_reductase chebi_ontology 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors C-14 sterol reductase inhibitor C-14 sterol reductase inhibitors Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors Delta(14)-sterol reductase inhibitor Delta(14)-sterol reductase inhibitors EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors EC 1.3.1.70 inhibitor EC 1.3.1.70 inhibitors sterol C14-reductase inhibitor sterol C14-reductase inhibitors CHEBI:83319 EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor CHEBI:83319 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor ChEBI 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors ChEBI C-14 sterol reductase inhibitor ChEBI C-14 sterol reductase inhibitors ChEBI Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor ChEBI Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors ChEBI Delta(14)-sterol reductase inhibitor ChEBI Delta(14)-sterol reductase inhibitors ChEBI EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors ChEBI EC 1.3.1.70 inhibitor ChEBI EC 1.3.1.70 inhibitors ChEBI sterol C14-reductase inhibitor ChEBI sterol C14-reductase inhibitors ChEBI A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tridecyl group. The configuration at positions 2 and 6 is unknown or unspecified. 0 C19H39NO InChI=1S/C19H39NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-20-16-18(2)21-19(3)17-20/h18-19H,4-17H2,1-3H3 YTOPFCCWCSOHFV-UHFFFAOYSA-N 297.51910 297.30316 CCCCCCCCCCCCCN1CC(C)OC(C)C1 CAS:24602-86-6 HMDB:HMDB0031810 KEGG:C11285 Reaxys:608429 (2Xi,6Xi)-2,6-dimethyl-4-tridecylmorpholine chebi_ontology N-tridecyl-2,6-dimethylmorpholine CHEBI:83365 2,6-dimethyl-4-tridecylmorpholine CHEBI:83365 CAS:24602-86-6 Alan Wood's Pesticides CAS:24602-86-6 ChemIDplus Reaxys:608429 Reaxys (2Xi,6Xi)-2,6-dimethyl-4-tridecylmorpholine IUPAC N-tridecyl-2,6-dimethylmorpholine ChEBI A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by an undecyl group. The configuration at positions 2 and 6 is unknown or unspecified. 0 C17H35NO InChI=1S/C17H35NO/c1-4-5-6-7-8-9-10-11-12-13-18-14-16(2)19-17(3)15-18/h16-17H,4-15H2,1-3H3 LVHAEMOCOJOUOD-UHFFFAOYSA-N 269.46590 269.27186 CCCCCCCCCCCN1CC(C)OC(C)C1 (2Xi,6Xi)-2,6-dimethyl-4-undecylmorpholine chebi_ontology 2,6-dimethyl-N-undecylmorpholine CHEBI:83368 2,6-dimethyl-4-undecylmorpholine CHEBI:83368 (2Xi,6Xi)-2,6-dimethyl-4-undecylmorpholine IUPAC 2,6-dimethyl-N-undecylmorpholine ChEBI A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tetradecyl group. The configuration at positions 2 and 6 is unknown or unspecified. 0 C20H41NO InChI=1S/C20H41NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-21-17-19(2)22-20(3)18-21/h19-20H,4-18H2,1-3H3 RHIAIJKBSAWEJK-UHFFFAOYSA-N 311.54560 311.31881 CCCCCCCCCCCCCCN1CC(C)OC(C)C1 Reaxys:8344499 (2Xi,6Xi)-2,6-dimethyl-4-tetradecylmorpholine chebi_ontology N-tetradecyl-2,6-dimethylmorpholine CHEBI:83370 2,6-dimethyl-4-tetradecylmorpholine CHEBI:83370 Reaxys:8344499 Reaxys (2Xi,6Xi)-2,6-dimethyl-4-tetradecylmorpholine IUPAC N-tetradecyl-2,6-dimethylmorpholine ChEBI Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms. chebi_ontology marine xenobiotic metabolites CHEBI:83399 marine xenobiotic metabolite CHEBI:83399 marine xenobiotic metabolites ChEBI Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. chebi_ontology CHEBI:83403 monochlorobenzenes CHEBI:83403 An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3. -1 O4SR 96.064 95.95173 [O-]S(=O)(=O)O[*] MetaCyc:Organo-Sulfates chebi_ontology alkyl sulfate anion an alkyl sulfate CHEBI:83414 alkyl sulfate(1-) CHEBI:83414 MetaCyc:Organo-Sulfates SUBMITTER alkyl sulfate anion ChEBI an alkyl sulfate UniProt Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent. monofluorobenzenes chebi_ontology CHEBI:83575 monofluorobenzenes CHEBI:83575 monofluorobenzenes ChEBI A carboxamide obtained by the formal condensation of the carboxy group of any carboxylic acid with ammonia. 0 CH2NOR 44.033 44.01364 NC([*])=O chebi_ontology a monocarboxylic acid amide CHEBI:83628 N-acylammonia CHEBI:83628 a monocarboxylic acid amide UniProt A member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group. 0 C17H12Cl2N2O InChI=1S/C17H12Cl2N2O/c18-14-7-5-12(6-8-14)17(22,13-9-20-11-21-10-13)15-3-1-2-4-16(15)19/h1-11,22H NHOWDZOIZKMVAI-UHFFFAOYSA-N 331.19600 330.03267 OC(c1ccc(Cl)cc1)(c1cncnc1)c1ccccc1Cl PPDB:291 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol chebi_ontology CHEBI:83686 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol CHEBI:83686 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol IUPAC A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has R configuration. 0 C17H12Cl2N2O InChI=1S/C17H12Cl2N2O/c18-14-7-5-12(6-8-14)17(22,13-9-20-11-21-10-13)15-3-1-2-4-16(15)19/h1-11,22H/t17-/m1/s1 NHOWDZOIZKMVAI-QGZVFWFLSA-N 331.19600 330.03267 O[C@](c1ccc(Cl)cc1)(c1cncnc1)c1ccccc1Cl PMID:22955670 (R)-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol chebi_ontology CHEBI:83688 (R)-fenarimol CHEBI:83688 PMID:22955670 Europe PMC (R)-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol IUPAC A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has S configuration. 0 C17H12Cl2N2O InChI=1S/C17H12Cl2N2O/c18-14-7-5-12(6-8-14)17(22,13-9-20-11-21-10-13)15-3-1-2-4-16(15)19/h1-11,22H/t17-/m0/s1 NHOWDZOIZKMVAI-KRWDZBQOSA-N 331.19600 330.03267 O[C@@](c1ccc(Cl)cc1)(c1cncnc1)c1ccccc1Cl PMID:22955670 (S)-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol chebi_ontology CHEBI:83689 (S)-fenarimol CHEBI:83689 PMID:22955670 Europe PMC (S)-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol IUPAC A tertiary alcohol that is ethanol in which one of the hydrogens at position 1 is replaced by an p-fluorophenyl group, the other hydrogen at position 1 is replaced by a p-fluorophenyl group, and one of the hydrogens at position 2 is replaced by a 1H-1,2,4-triazol-1-yl group. 0 C16H13F2N3O InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 JWUCHKBSVLQQCO-UHFFFAOYSA-N 301.29070 301.10267 OC(Cn1cncn1)(c1ccc(F)cc1)c1ccccc1F PPDB:353 chebi_ontology CHEBI:83707 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol CHEBI:83707 A 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol that has R configuration. 0 C16H13F2N3O InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2/t16-/m1/s1 JWUCHKBSVLQQCO-MRXNPFEDSA-N 301.29070 301.10267 O[C@](Cn1cncn1)(c1ccc(F)cc1)c1ccccc1F PMID:21740052 PMID:24611465 PMID:25300182 PMID:25376483 PPDB:3114 (1R)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol chebi_ontology (-)-flutriafol (R)-(-)-flutriafol CHEBI:83708 (R)-flutriafol CHEBI:83708 PMID:21740052 Europe PMC PMID:24611465 Europe PMC PMID:25300182 Europe PMC PMID:25376483 Europe PMC (1R)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol IUPAC (-)-flutriafol ChEBI (R)-(-)-flutriafol ChEBI A 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol that has R configuration. 0 C16H13F2N3O InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2/t16-/m0/s1 JWUCHKBSVLQQCO-INIZCTEOSA-N 301.29070 301.10267 O[C@@](Cn1cncn1)(c1ccc(F)cc1)c1ccccc1F PMID:21740052 PMID:24611465 PMID:25300182 PMID:25376483 PPDB:3115 (1S)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol chebi_ontology (+)-flutriafol (S)-(+)-flutriafol CHEBI:83709 (S)-flutriafol CHEBI:83709 PMID:21740052 Europe PMC PMID:24611465 Europe PMC PMID:25300182 Europe PMC PMID:25376483 Europe PMC (1S)-1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol IUPAC (+)-flutriafol ChEBI (S)-(+)-flutriafol ChEBI A member of the class of oxazolidinones that is 5-ethenyl-5-methyl-2,4-oxazolidinedione in which the imide hydrogen is replaced by a 3,5-dichlorophenyl group. 0 C12H9Cl2NO3 InChI=1S/C12H9Cl2NO3/c1-3-12(2)10(16)15(11(17)18-12)9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3 FSCWZHGZWWDELK-UHFFFAOYSA-N 286.11100 284.99595 CC1(OC(=O)N(C1=O)c1cc(Cl)cc(Cl)c1)C=C PPDB:680 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione chebi_ontology CHEBI:83732 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione CHEBI:83732 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione IUPAC A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (R)-enantiomer of vinclozolin. 0 C12H9Cl2NO3 InChI=1S/C12H9Cl2NO3/c1-3-12(2)10(16)15(11(17)18-12)9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3/t12-/m1/s1 FSCWZHGZWWDELK-GFCCVEGCSA-N 286.11100 284.99595 C[C@@]1(OC(=O)N(C1=O)c1cc(Cl)cc(Cl)c1)C=C Reaxys:8626241 (5R)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione chebi_ontology CHEBI:83733 (R)-vinclozolin CHEBI:83733 Reaxys:8626241 Reaxys (5R)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione IUPAC A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis. chebi_ontology sterol demethylation inhibitors CHEBI:83734 sterol demethylation inhibitor CHEBI:83734 sterol demethylation inhibitors ChEBI A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (S)-enantiomer of vinclozolin. 0 C12H9Cl2NO3 InChI=1S/C12H9Cl2NO3/c1-3-12(2)10(16)15(11(17)18-12)9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3/t12-/m0/s1 FSCWZHGZWWDELK-LBPRGKRZSA-N 286.11100 284.99595 C[C@]1(OC(=O)N(C1=O)c1cc(Cl)cc(Cl)c1)C=C (5S)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione chebi_ontology CHEBI:83735 (S)-vinclozolin CHEBI:83735 (5S)-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione IUPAC A tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1H-1,2,4-triazol-1-yl group at position 1. 0 C15H18ClN3O InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3 UFNOUKDBUJZYDE-UHFFFAOYSA-N 291.77600 291.11384 CC(C1CC1)C(O)(Cn1cncn1)c1ccc(Cl)cc1 PPDB:198 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology CHEBI:83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol CHEBI:83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC The (2R,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. 0 C15H18ClN3O InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3/t11-,15+/m0/s1 UFNOUKDBUJZYDE-XHDPSFHLSA-N 291.77600 291.11384 C[C@@H](C1CC1)[C@](O)(Cn1cncn1)c1ccc(Cl)cc1 (2R,3S)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology CHEBI:83749 (2R,3S)-cyproconazole CHEBI:83749 (2R,3S)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC The (2S,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. 0 C15H18ClN3O InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3/t11-,15-/m0/s1 UFNOUKDBUJZYDE-NHYWBVRUSA-N 291.77600 291.11384 C[C@@H](C1CC1)[C@@](O)(Cn1cncn1)c1ccc(Cl)cc1 (2S,3S)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology CHEBI:83750 (2S,3S)-cyproconazole CHEBI:83750 (2S,3S)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC The (2S,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. 0 C15H18ClN3O InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3/t11-,15+/m1/s1 UFNOUKDBUJZYDE-ABAIWWIYSA-N 291.77600 291.11384 C[C@H](C1CC1)[C@@](O)(Cn1cncn1)c1ccc(Cl)cc1 (2S,3R)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology CHEBI:83752 (2S,3R)-cyproconazole CHEBI:83752 (2S,3R)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC The (2R,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. 0 C15H18ClN3O InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3/t11-,15-/m1/s1 UFNOUKDBUJZYDE-IAQYHMDHSA-N 291.77600 291.11384 C[C@H](C1CC1)[C@](O)(Cn1cncn1)c1ccc(Cl)cc1 (2R,3R)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol chebi_ontology CHEBI:83753 (2R,3R)-cyproconazole CHEBI:83753 (2R,3R)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol IUPAC An epoxide that is oxirane substituted by a 2-chlorophenyl, 4-fluorophenyl and a 1H-1,2,4-triazol-1-ylmethyl groups. 0 C17H13ClFN3O InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2 ZMYFCFLJBGAQRS-UHFFFAOYSA-N 329.75600 329.07312 Fc1ccc(cc1)C1(Cn2cncn2)OC1c1ccccc1Cl 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole chebi_ontology CHEBI:83758 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole CHEBI:83758 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole IUPAC The (2S,3R)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole. 0 C17H13ClFN3O InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2/t16-,17-/m1/s1 ZMYFCFLJBGAQRS-IAGOWNOFSA-N 329.75600 329.07312 Fc1ccc(cc1)[C@@]1(Cn2cncn2)O[C@@H]1c1ccccc1Cl KEGG:C11229 1-{[(2S,3R)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole chebi_ontology CHEBI:83759 (2S,3R)-epoxiconazole CHEBI:83759 1-{[(2S,3R)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole IUPAC The (2R,3S)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole. 0 C17H13ClFN3O InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2/t16-,17-/m0/s1 ZMYFCFLJBGAQRS-IRXDYDNUSA-N 329.75600 329.07312 Fc1ccc(cc1)[C@]1(Cn2cncn2)O[C@H]1c1ccccc1Cl 1-{[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole chebi_ontology CHEBI:83761 (2R,3S)-epoxiconazole CHEBI:83761 1-{[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole IUPAC A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively. 0 C16H22ClN3O InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3 PXMNMQRDXWABCY-UHFFFAOYSA-N 307.81800 307.14514 CC(C)(C)C(O)(CCc1ccc(Cl)cc1)Cn1cncn1 PPDB:610 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol chebi_ontology CHEBI:83779 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol CHEBI:83779 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol IUPAC The (S)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. 0 C16H22ClN3O InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3/t16-/m1/s1 PXMNMQRDXWABCY-MRXNPFEDSA-N 307.81800 307.14514 CC(C)(C)[C@@](O)(CCc1ccc(Cl)cc1)Cn1cncn1 Reaxys:5749276 (3S)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol chebi_ontology CHEBI:83780 (S)-tebuconazole CHEBI:83780 Reaxys:5749276 Reaxys (3S)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol IUPAC The (R)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. 0 C16H22ClN3O InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3/t16-/m0/s1 PXMNMQRDXWABCY-INIZCTEOSA-N 307.81800 307.14514 CC(C)(C)[C@](O)(CCc1ccc(Cl)cc1)Cn1cncn1 Reaxys:5749275 (3R)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol chebi_ontology CHEBI:83781 (R)-tebuconazole CHEBI:83781 Reaxys:5749275 Reaxys (3R)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol IUPAC Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom. chebi_ontology canonical amino acid derivative canonical amino acid derivatives canonical amino-acid derivative canonical amino-acid derivatives proteinogenic amino acid derivatives proteinogenic amino-acid derivative proteinogenic amino-acid derivatives CHEBI:83811 proteinogenic amino acid derivative CHEBI:83811 canonical amino acid derivative ChEBI canonical amino acid derivatives ChEBI canonical amino-acid derivative ChEBI canonical amino-acid derivatives ChEBI proteinogenic amino acid derivatives ChEBI proteinogenic amino-acid derivative ChEBI proteinogenic amino-acid derivatives ChEBI Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration. Wikipedia:Proteinogenic_amino_acid chebi_ontology canonical amino acid canonical amino acids proteinogenic amino acids CHEBI:83813 proteinogenic amino acid CHEBI:83813 canonical amino acid ChEBI canonical amino acids ChEBI proteinogenic amino acids ChEBI Any amino-acid that is not naturally encoded in the genetic code of any organism. Wikipedia:Non-proteinogenic_amino_acids chebi_ontology non-canonical amino acid non-canonical amino acids non-canonical amino-acid non-canonical amino-acids non-coded amino acid non-coded amino acids non-coded amino-acid non-coded amino-acids non-proteinogenic amino acids non-proteinogenic amino-acid non-proteinogenic amino-acids CHEBI:83820 non-proteinogenic amino acid CHEBI:83820 non-canonical amino acid ChEBI non-canonical amino acids ChEBI non-canonical amino-acid ChEBI non-canonical amino-acids ChEBI non-coded amino acid ChEBI non-coded amino acids ChEBI non-coded amino-acid ChEBI non-coded amino-acids ChEBI non-proteinogenic amino acids ChEBI non-proteinogenic amino-acid ChEBI non-proteinogenic amino-acids ChEBI Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues. CHEBI:25359 chebi_ontology amino acid derivatives modified amino acids CHEBI:83821 amino acid derivative CHEBI:83821 amino acid derivatives ChEBI modified amino acids ChEBI An organic cation obtained by protonation of the amino function of any sphingoid chebi_ontology cationic sphingoids sphingoid cation sphingoid cations CHEBI:83876 cationic sphingoid CHEBI:83876 cationic sphingoids ChEBI sphingoid cation ChEBI sphingoid cations ChEBI A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the (S)-enantiomer of diniconazole. 0 C15H17Cl2N3O InChI=1S/C15H17Cl2N3O/c1-15(2,3)14(21)13(20-9-18-8-19-20)6-10-4-5-11(16)7-12(10)17/h4-9,14,21H,1-3H3/b13-6+/t14-/m1/s1 FBOUIAKEJMZPQG-YGLIYXGISA-N 326.22100 325.07487 CC(C)(C)[C@H](O)C(=C/c1ccc(Cl)cc1Cl)\n1cncn1 CAS:83657-19-6 PMID:24009183 PMID:24211030 PMID:30401538 Reaxys:9634907 (1E,3S)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol chebi_ontology (+)-diniconazole S-(+)-diniconazole diniconazole (+)-form CHEBI:83906 (S)-diniconazole CHEBI:83906 CAS:83657-19-6 ChemIDplus PMID:24009183 Europe PMC PMID:24211030 Europe PMC PMID:30401538 Europe PMC Reaxys:9634907 Reaxys (1E,3S)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol IUPAC (+)-diniconazole ChEBI S-(+)-diniconazole ChEBI diniconazole (+)-form ChemIDplus A member of the class of triazoles that is 4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol substituted at position 1 by a 2,4-dichlorophenyl group. 0 C15H17Cl2N3O InChI=1S/C15H17Cl2N3O/c1-15(2,3)14(21)13(20-9-18-8-19-20)6-10-4-5-11(16)7-12(10)17/h4-9,14,21H,1-3H3/b13-6+ FBOUIAKEJMZPQG-AWNIVKPZSA-N 326.22100 325.07487 CC(C)(C)C(O)C(=C/c1ccc(Cl)cc1Cl)\n1cncn1 PPDB:247 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol chebi_ontology CHEBI:83909 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol CHEBI:83909 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol IUPAC A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the active R-enantiomer of diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts. 0 C15H17Cl2N3O InChI=1S/C15H17Cl2N3O/c1-15(2,3)14(21)13(20-9-18-8-19-20)6-10-4-5-11(16)7-12(10)17/h4-9,14,21H,1-3H3/b13-6+/t14-/m0/s1 FBOUIAKEJMZPQG-BLXFFLACSA-N 326.22100 325.07487 CC(C)(C)[C@@H](O)C(=C/c1ccc(Cl)cc1Cl)\n1cncn1 CAS:83657-18-5 PMID:23056532 PMID:30401538 PPDB:2907 Pesticides:diniconazole-m Reaxys:7381524 (1E,3R)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol chebi_ontology (-)-diniconazole (E)-(R)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol (R)-diniconazole R-(-)-diniconazole diniconazole (-) CHEBI:83911 diniconazole-M CHEBI:83911 CAS:83657-18-5 ChemIDplus PMID:23056532 Europe PMC PMID:30401538 Europe PMC Pesticides:diniconazole-m Alan Wood's Pesticides Reaxys:7381524 Reaxys (1E,3R)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol IUPAC (-)-diniconazole ChEBI (E)-(R)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol Alan_Wood's_Pesticides (R)-diniconazole ChEBI R-(-)-diniconazole ChEBI diniconazole (-) ChemIDplus Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids. chebi_ontology non-proteinogenic alpha-amino acids non-proteinogenic alpha-amino-acid non-proteinogenic alpha-amino-acids CHEBI:83925 non-proteinogenic alpha-amino acid CHEBI:83925 non-proteinogenic alpha-amino acids ChEBI non-proteinogenic alpha-amino-acid ChEBI non-proteinogenic alpha-amino-acids ChEBI A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid. -1 C2H2O2R 58.036 58.00548 [O-]C(=O)C[*] chebi_ontology 1,2-saturated fatty acid anion a 1,2-saturated fatty acid CHEBI:83955 2-saturated fatty acid anion CHEBI:83955 1,2-saturated fatty acid anion ChEBI a 1,2-saturated fatty acid UniProt A dithiocarbamic acid resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine. 0 C4H8N2S4 InChI=1S/C4H8N2S4/c7-3(8)5-1-2-6-4(9)10/h1-2H2,(H2,5,7,8)(H2,6,9,10) AWYFNIZYMPNGAI-UHFFFAOYSA-N 212.38000 211.95703 SC(=S)NCCNC(S)=S CAS:111-54-6 Reaxys:1772091 ethane-1,2-diyldicarbamodithioic acid chebi_ontology N,N'-(ethylene)bisdithiocarbamic acid N,N'-ethanediylbis(dithiocarbamic acid) ethylenebisdithiocarbamic acid CHEBI:83986 ethylenebis(dithiocarbamic acid) CHEBI:83986 CAS:111-54-6 ChemIDplus Reaxys:1772091 Reaxys ethane-1,2-diyldicarbamodithioic acid IUPAC N,N'-(ethylene)bisdithiocarbamic acid ChEBI N,N'-ethanediylbis(dithiocarbamic acid) ChEBI ethylenebisdithiocarbamic acid ChemIDplus A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group. 0 C14H16ClN3O2 InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3 WURBVZBTWMNKQT-UHFFFAOYSA-N 293.74900 293.09310 CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1 LINCS:LSM-4424 PPDB:648 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one chebi_ontology CHEBI:84002 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one CHEBI:84002 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one IUPAC A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (R)-enantiomer of triadimefon. 0 C14H16ClN3O2 InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3/t13-/m1/s1 WURBVZBTWMNKQT-CYBMUJFWSA-N 293.74900 293.09310 CC(C)(C)C(=O)[C@@H](Oc1ccc(Cl)cc1)n1cncn1 CAS:73804-20-3 Reaxys:20863307 (1R)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one chebi_ontology CHEBI:84003 (R)-triadimefon CHEBI:84003 CAS:73804-20-3 ChemIDplus Reaxys:20863307 Reaxys (1R)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one IUPAC A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (S)-enantiomer of triadimefon. 0 C14H16ClN3O2 InChI=1S/C14H16ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,13H,1-3H3/t13-/m0/s1 WURBVZBTWMNKQT-ZDUSSCGKSA-N 293.74900 293.09310 CC(C)(C)C(=O)[C@H](Oc1ccc(Cl)cc1)n1cncn1 CAS:89497-67-6 Reaxys:20863308 (1S)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one chebi_ontology CHEBI:84004 (S)-triadimefon CHEBI:84004 CAS:89497-67-6 ChemIDplus Reaxys:20863308 Reaxys (1S)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one IUPAC Any phospho sugar that is the phosphate derivative of pentose. chebi_ontology pentose phosphates CHEBI:84055 pentose phosphate CHEBI:84055 pentose phosphates ChEBI Any metabolite (endogenous or exogenous) found in human urine samples. chebi_ontology human urinary metabolites CHEBI:84087 human urinary metabolite CHEBI:84087 human urinary metabolites ChEBI A proteinogenic amino acid derivative resulting from reaction of L-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of L-proline by a heteroatom. chebi_ontology L-proline derivatives CHEBI:84186 L-proline derivative CHEBI:84186 L-proline derivatives ChEBI An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). Wikipedia:Nicotinamidase chebi_ontology EC 3.5.1.19 (nicotinamidase) inhibitors EC 3.5.1.19 inhibitor EC 3.5.1.19 inhibitors YNDase inhibitor YNDase inhibitors nicotinamidase (EC 3.5.1.19) inhibitor nicotinamidase (EC 3.5.1.19) inhibitors nicotinamidase inhibitor nicotinamidase inhibitors nicotinamide amidase inhibitor nicotinamide amidase inhibitors nicotinamide amidohydrolase inhibitor nicotinamide amidohydrolase inhibitors nicotinamide deaminase inhibitor nicotinamide deaminase inhibitors CHEBI:84264 EC 3.5.1.19 (nicotinamidase) inhibitor CHEBI:84264 EC 3.5.1.19 (nicotinamidase) inhibitors ChEBI EC 3.5.1.19 inhibitor ChEBI EC 3.5.1.19 inhibitors ChEBI YNDase inhibitor ChEBI YNDase inhibitors ChEBI nicotinamidase (EC 3.5.1.19) inhibitor ChEBI nicotinamidase (EC 3.5.1.19) inhibitors ChEBI nicotinamidase inhibitor ChEBI nicotinamidase inhibitors ChEBI nicotinamide amidase inhibitor ChEBI nicotinamide amidase inhibitors ChEBI nicotinamide amidohydrolase inhibitor ChEBI nicotinamide amidohydrolase inhibitors ChEBI nicotinamide deaminase inhibitor ChEBI nicotinamide deaminase inhibitors ChEBI An organic anion in which the charge resides on a sulfur atom. chebi_ontology organic sulfur anions CHEBI:84291 organic sulfur anion CHEBI:84291 organic sulfur anions ChEBI Any organic sulfur anion resulting from the removal of a proton from any N-substituted dithiocarbamic acid. -1 CNS2R2 90.14800 89.94722 [S-]C(=S)N([*])[*] chebi_ontology CHEBI:84292 dithiocarbamate anions CHEBI:84292 A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables. 0 C15H16Cl3N3O2 InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3 TVLSRXXIMLFWEO-UHFFFAOYSA-N 376.66500 375.03081 CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1 CAS:67747-09-5 KEGG:C11182 PMID:24401010 PMID:24964350 PMID:25163568 PPDB:536 Pesticides:prochloraz Reaxys:8155344 N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide chebi_ontology CHEBI:8434 prochloraz CHEBI:8434 CAS:67747-09-5 ChemIDplus CAS:67747-09-5 KEGG COMPOUND PMID:24401010 Europe PMC PMID:24964350 Europe PMC PMID:25163568 Europe PMC Pesticides:prochloraz Alan Wood's Pesticides Reaxys:8155344 Reaxys N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide IUPAC Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. chebi_ontology algal metabolites CHEBI:84735 algal metabolite CHEBI:84735 algal metabolites ChEBI An organic cation obtained by protonation of the four free amino groups of amikacin; major species at pH 7.3. +4 C22H47N5O13 InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/p+4/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1 LKCWBDHBTVXHDL-RMDFUYIESA-R 589.63210 589.31484 [NH3+]CC[C@H](O)C(=O)N[C@@H]1C[C@H]([NH3+])[C@@H](O[C@H]2O[C@H](C[NH3+])[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H]([NH3+])[C@H]1O (1S,2S,3R,4S,6R)-4-azaniumyl-3-[(6-azaniumyl-6-deoxy-alpha-D-glucopyranosyl)oxy]-6-{[(2S)-4-azaniumyl-2-hydroxybutanoyl]amino}-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside chebi_ontology CHEBI:84739 amikacin(4+) CHEBI:84739 (1S,2S,3R,4S,6R)-4-azaniumyl-3-[(6-azaniumyl-6-deoxy-alpha-D-glucopyranosyl)oxy]-6-{[(2S)-4-azaniumyl-2-hydroxybutanoyl]amino}-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside IUPAC The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds. 0 C15H17Cl2N3O2 InChI=1S/C15H17Cl2N3O2/c1-2-3-12-7-21-15(22-12,8-20-10-18-9-19-20)13-5-4-11(16)6-14(13)17/h4-6,9-10,12H,2-3,7-8H2,1H3 STJLVHWMYQXCPB-UHFFFAOYSA-N 342.22000 341.06978 CCCC1COC(Cn2cncn2)(O1)c1ccc(Cl)cc1Cl CHEBI:658576 CAS:60207-90-1 CAS:75881-82-2 KEGG:C11121 MetaCyc:CPD-14540 PMID:19128860 PPDB:551 Patent:DE2551560 Patent:US4079062 Pesticides:propiconazole Reaxys:841361 Wikipedia:Propiconazole 1-{[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole Propiconazole chebi_ontology (+-)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole CHEBI:8489 propiconazole CHEBI:8489 CAS:60207-90-1 ChemIDplus CAS:60207-90-1 KEGG COMPOUND CAS:75881-82-2 NIST Chemistry WebBook PMID:19128860 ChEMBL Pesticides:propiconazole Alan Wood's Pesticides Reaxys:841361 Reaxys 1-{[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole IUPAC Propiconazole KEGG_COMPOUND (+-)-1-[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole ChEBI A teicoplanin A2 that has 8-methylnonanoyl as the variable N-acyl group. 0 C88H97Cl2N9O33 InChI=1S/C88H97Cl2N9O33/c1-33(2)8-6-4-5-7-9-60(108)94-68-74(113)71(110)58(31-101)129-87(68)132-78-55-25-40-26-56(78)126-52-17-13-38(23-47(52)90)77(131-86-67(92-34(3)103)73(112)70(109)57(30-100)128-86)69-84(121)98-66(85(122)123)45-28-42(105)29-54(127-88-76(115)75(114)72(111)59(32-102)130-88)61(45)44-22-37(12-14-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-20-41(104)27-43(21-39)124-53-24-36(11-15-50(53)107)62(91)80(117)93-48(79(116)95-64)19-35-10-16-51(125-55)46(89)18-35/h10-18,20-29,33,48,57-59,62-77,86-88,100-102,104-107,109-115H,4-9,19,30-32,91H2,1-3H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/t48-,57-,58-,59-,62-,63-,64+,65-,66+,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1 GHOXVFYORXUCPY-PKMGYIMSSA-N 1879.65800 1877.55658 CC(C)CCCCCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc1c2Oc3ccc(C[C@H]4NC(=O)[C@H](N)c5ccc(O)c(Oc6cc(O)cc(c6)[C@H](NC4=O)C(=O)N[C@@H]4c(c2)cc1Oc1ccc(cc1Cl)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)[C@@H]1NC(=O)[C@H](NC4=O)c2ccc(O)c(c2)-c2c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc(O)cc2[C@H](NC1=O)C(O)=O)c5)cc3Cl CAS:91032-26-7 PMID:11833531 PMID:25095906 PMID:25147913 Patent:US4542018 Reaxys:7508820 teicoplanin A2-2 chebi_ontology 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxononyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(8-methyl-1-oxononyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone teichomycin A2 factor 2 CHEBI:85251 teicoplanin A2-2 CHEBI:85251 CAS:91032-26-7 ChemIDplus PMID:11833531 Europe PMC PMID:25095906 Europe PMC PMID:25147913 Europe PMC Reaxys:7508820 Reaxys teicoplanin A2-2 ChemIDplus 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxononyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone ChemIDplus 34-O-[2-(acetamido)-2-deoxy-beta-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-{2-deoxy-2-[(8-methyl-1-oxononyl)amino]-beta-D-glucopyranosyl}-42-O-alpha-D-mannopyranosylristomycin A aglycone ChEBI teichomycin A2 factor 2 ChemIDplus A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. CHEBI:60593 chebi_ontology azole antibiotic azole antibiotics conazole antifungal agents CHEBI:86323 conazole antifungal agent CHEBI:86323 azole antibiotic ChEBI azole antibiotics ChEBI conazole antifungal agents ChEBI An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton. chebi_ontology quinolone antibiotics CHEBI:86324 quinolone antibiotic CHEBI:86324 quinolone antibiotics ChEBI Any antifungal agent used to prevent or treat fungal infections in humans or animals. Wikipedia:Antifungal chebi_ontology anti-fungal drug anti-fungal drugs anti-fungal medication anti-fungal medications antifungal drugs antifungal medication antifungal medications pharmaceutical fungicide pharmaceutical fungicides CHEBI:86327 antifungal drug CHEBI:86327 anti-fungal drug ChEBI anti-fungal drugs ChEBI anti-fungal medication ChEBI anti-fungal medications ChEBI antifungal drugs ChEBI antifungal medication ChEBI antifungal medications ChEBI pharmaceutical fungicide ChEBI pharmaceutical fungicides ChEBI Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. chebi_ontology agrichemical fungicide agrichemical fungicides agrochemical fungicide agrochemical fungicides anti-fungal agrichemical anti-fungal agrichemicals anti-fungal agrochemical anti-fungal agrochemicals antifungal agrichemical antifungal agrichemicals antifungal agrochemicals CHEBI:86328 antifungal agrochemical CHEBI:86328 agrichemical fungicide ChEBI agrichemical fungicides ChEBI agrochemical fungicide ChEBI agrochemical fungicides ChEBI anti-fungal agrichemical ChEBI anti-fungal agrichemicals ChEBI anti-fungal agrochemical ChEBI anti-fungal agrochemicals ChEBI antifungal agrichemical ChEBI antifungal agrichemicals ChEBI antifungal agrochemicals ChEBI Either of the two diastereoisomers of 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the imidazol-1-ylmethyl group and the aryloxymethyl group are in a cis relationship to each other - i.e. they are both on the same side of the plane of the dioxolane ring. The antifungal drug ketoconazole is a racemic mixture of the two cis diastereoisomers. chebi_ontology CHEBI:86411 cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine CHEBI:86411 A compound that has significant antifungal properties whose structure contains an imidazole moiety. chebi_ontology imidazole antifungal agents CHEBI:86420 imidazole antifungal agent CHEBI:86420 imidazole antifungal agents ChEBI A member of the class of triazole that has significant antifungal properties. chebi_ontology triazole antifungal agents CHEBI:86426 triazole antifungal agent CHEBI:86426 triazole antifungal agents ChEBI Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties. chebi_ontology antibiotic antifungal agents CHEBI:86478 antibiotic antifungal agent CHEBI:86478 antibiotic antifungal agents ChEBI Any antibiotic antifungal agents whose structure is based on the antifungal agents originally isolated from the fungus Strobilurus tenacellus. Wikipedia:Strobilurin chebi_ontology strobilurin antifungal agents CHEBI:86482 strobilurin antifungal agent CHEBI:86482 strobilurin antifungal agents ChEBI Any strobilurin antifungal agent that contains a methoxyacrylate group. chebi_ontology methoxyacrylate strobilurin antifungal agents CHEBI:86484 methoxyacrylate strobilurin antifungal agent CHEBI:86484 methoxyacrylate strobilurin antifungal agents ChEBI An iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. An antibiotic pigment produced by Pseudomonas aeruginosa. 0 C13H10N2O InChI=1S/C13H10N2O/c1-15-10-6-3-2-5-9(10)14-13-11(15)7-4-8-12(13)16/h2-8H,1H3 YNCMLFHHXWETLD-UHFFFAOYSA-N 210.236 210.07931 C[N+]1=C2C=CC=CC2=NC2=C1C=CC=C2[O-] CHEBI:137500 CAS:85-66-5 Chemspider:6558 KEGG:C01748 MetaCyc:CPD-12847 PDBeChem:3J8 PMID:21888766 PMID:27322205 PMID:27517959 PMID:27559393 PMID:27940577 PMID:28333255 PMID:28408162 PMID:28558232 PMID:28607159 PMID:31647218 PMID:31981486 PMID:32417365 PMID:32707314 PMID:32763156 PMID:33398400 PMID:33545813 PMID:33578646 Reaxys:11862 Wikipedia:Pyocyanin 5-methylphenazin-5-ium-1-olate chebi_ontology pyocyanin CHEBI:8653 pyocyanine CHEBI:8653 CAS:85-66-5 ChemIDplus CAS:85-66-5 KEGG COMPOUND PMID:21888766 Europe PMC PMID:27322205 Europe PMC PMID:27517959 Europe PMC PMID:27559393 Europe PMC PMID:27940577 Europe PMC PMID:28333255 Europe PMC PMID:28408162 Europe PMC PMID:28558232 Europe PMC PMID:28607159 Europe PMC PMID:31647218 Europe PMC PMID:31981486 Europe PMC PMID:32417365 Europe PMC PMID:32707314 Europe PMC PMID:32763156 Europe PMC PMID:33398400 Europe PMC PMID:33545813 Europe PMC PMID:33578646 Europe PMC Reaxys:11862 Reaxys 5-methylphenazin-5-ium-1-olate IUPAC pyocyanin ChEBI A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine. 0 C12H13N3 InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15) ZLIBICFPKPWGIZ-UHFFFAOYSA-N 199.25170 199.11095 Cc1cc(C)nc(Nc2ccccc2)n1 CAS:53112-28-0 HMDB:HMDB0033135 KEGG:C11180 PMID:22949075 PMID:23246620 PMID:23258318 PMID:23410121 PMID:23436777 PMID:23673061 PMID:23993516 PMID:24081744 PMID:24365971 PMID:24380616 PMID:24652239 PMID:24835131 PMID:25145229 PMID:25216469 PPDB:573 Pesticides:pyrimethanil Reaxys:151589 Wikipedia:Pyrimethanil 4,6-dimethyl-N-phenylpyrimidin-2-amine chebi_ontology 2-Anilino-4,6-dimethylpyrimidine 4,6-Dimethyl-N-phenyl-2-pyrimidinamine N-(4,6-dimethylpyrimidin-2-yl)aniline CHEBI:8674 pyrimethanil CHEBI:8674 CAS:53112-28-0 ChemIDplus CAS:53112-28-0 KEGG COMPOUND CAS:53112-28-0 NIST Chemistry WebBook PMID:22949075 Europe PMC PMID:23246620 Europe PMC PMID:23258318 Europe PMC PMID:23410121 Europe PMC PMID:23436777 Europe PMC PMID:23673061 Europe PMC PMID:23993516 Europe PMC PMID:24081744 Europe PMC PMID:24365971 Europe PMC PMID:24380616 Europe PMC PMID:24652239 Europe PMC PMID:24835131 Europe PMC PMID:25145229 Europe PMC PMID:25216469 Europe PMC Pesticides:pyrimethanil Alan Wood's Pesticides Reaxys:151589 Reaxys 4,6-dimethyl-N-phenylpyrimidin-2-amine IUPAC 2-Anilino-4,6-dimethylpyrimidine HMDB 4,6-Dimethyl-N-phenyl-2-pyrimidinamine HMDB N-(4,6-dimethylpyrimidin-2-yl)aniline Alan_Wood's_Pesticides A compound that has significant antifungal properties whose structure contains an amide moiety. chebi_ontology amide antifungal agents CHEBI:87012 amide antifungal agent CHEBI:87012 amide antifungal agents ChEBI Any amide fungicide whose structure contains an anilide group. chebi_ontology anilide fungicides CHEBI:87015 anilide fungicide CHEBI:87015 anilide fungicides ChEBI An organic aromatic compound that has been used as a fungicide. chebi_ontology aromatic fungicides CHEBI:87034 aromatic fungicide CHEBI:87034 aromatic fungicides ChEBI Compounds that contain a benzimidazole moiety as a key feature of their structure and which have been used as fungicides. chebi_ontology benzimidazole fungicides CHEBI:87036 benzimidazole fungicide CHEBI:87036 benzimidazole fungicides ChEBI Compounds based on 1,2-phenylenediamine in which one or both of the primary amino groups have been derivatised so as to permit subsequent benzimidazole formation, and which have been used as fungicides. chebi_ontology benzimidazole precursor fungicides CHEBI:87037 benzimidazole precursor fungicide CHEBI:87037 benzimidazole precursor fungicides ChEBI Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides. chebi_ontology carbamate fungicides CHEBI:87061 carbamate fungicide CHEBI:87061 carbamate fungicides ChEBI Any carbamate fungicide that contains a benzimidazolyl group attached to the nitrogen of the carbamate moiety. chebi_ontology benzimidazolylcarbamate fungicides CHEBI:87064 benzimidazolylcarbamate fungicide CHEBI:87064 benzimidazolylcarbamate fungicides ChEBI Any carbamate fungicide that has a phenyl or substituted-phenyl group attached to the nitrogen of the carbamate group. chebi_ontology carbanilate fungicides CHEBI:87066 carbanilate fungicide CHEBI:87066 carbanilate fungicides ChEBI Any conazole antifungal agent that has been used as a fungicide. chebi_ontology conazole fungicides CHEBI:87067 conazole fungicide CHEBI:87067 conazole fungicides ChEBI Any imidazole antifungal agent that has been used as a fungicide. chebi_ontology imidazole fungicides CHEBI:87068 imidazole fungicide CHEBI:87068 imidazole fungicides ChEBI Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. chebi_ontology imidazole antifungal drugs CHEBI:87069 imidazole antifungal drug CHEBI:87069 imidazole antifungal drugs ChEBI Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans. chebi_ontology conazole antifungal drugs CHEBI:87071 conazole antifungal drug CHEBI:87071 conazole antifungal drugs ChEBI Any triazole antifungal agent that has been used as a fungicide. chebi_ontology triazole fungicides CHEBI:87100 triazole fungicide CHEBI:87100 triazole fungicides ChEBI Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. chebi_ontology triazole antifungal drugs CHEBI:87101 triazole antifungal drug CHEBI:87101 triazole antifungal drugs ChEBI Any antibiotic antifungal agent used to treat fungal infections in humans or animals. chebi_ontology antibiotic antifungal drugs CHEBI:87113 antibiotic antifungal drug CHEBI:87113 antibiotic antifungal drugs ChEBI Any antibiotic antifungal agent that has been used as a fungicide. chebi_ontology antibiotic fungicides CHEBI:87114 antibiotic fungicide CHEBI:87114 antibiotic fungicides ChEBI An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug. PMID:1732066 chebi_ontology allylamine antifungal drugs CHEBI:87127 allylamine antifungal drug CHEBI:87127 PMID:1732066 Europe PMC allylamine antifungal drugs ChEBI A member of the class of morpholines that has significant antifungal properties. chebi_ontology morpholine antifungal agents CHEBI:87132 morpholine antifungal agent CHEBI:87132 morpholine antifungal agents ChEBI Any morpholine antifungal agent used as a fungicide. chebi_ontology morpholine fungicides CHEBI:87134 morpholine fungicide CHEBI:87134 morpholine fungicides ChEBI A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture. 0 C12H14Cl2FNO4S InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1 AYIRNRDRBQJXIF-NXEZZACHSA-N 358.21300 357.00046 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl CAS:73231-34-2 KEGG:D04194 LINCS:LSM-5287 PMID:25287575 PMID:25395188 PMID:25567063 PMID:25572306 PMID:25612770 PMID:25614968 PMID:25618189 PMID:25623169 PMID:25675893 PMID:25686865 PMID:25706107 PMID:25723132 PMID:25744433 PMID:25771961 PMID:25827198 PMID:25830490 PMID:25886128 PMID:25886555 PMID:25891823 PMID:25913426 PMID:25973625 PMID:26025252 PMID:26049592 Patent:EP14437 Patent:US4235892 Reaxys:4202553 VSDB:1777 Wikipedia:Florfenicol 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide chebi_ontology (-)-Florfenicol D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide Nuflor Nuflor gold Sch 25298 Sch-25298 florfenicol CHEBI:87185 florfenicol CHEBI:87185 CAS:73231-34-2 KEGG DRUG PMID:25287575 Europe PMC PMID:25395188 Europe PMC PMID:25567063 Europe PMC PMID:25572306 Europe PMC PMID:25612770 Europe PMC PMID:25614968 Europe PMC PMID:25618189 Europe PMC PMID:25623169 Europe PMC PMID:25675893 Europe PMC PMID:25686865 Europe PMC PMID:25706107 Europe PMC PMID:25723132 Europe PMC PMID:25744433 Europe PMC PMID:25771961 Europe PMC PMID:25827198 Europe PMC PMID:25830490 Europe PMC PMID:25886128 Europe PMC PMID:25886555 Europe PMC PMID:25891823 Europe PMC PMID:25913426 Europe PMC PMID:25973625 Europe PMC PMID:26025252 Europe PMC PMID:26049592 Europe PMC Reaxys:4202553 Reaxys 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide IUPAC (-)-Florfenicol ChemIDplus D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide ChemIDplus Nuflor KEGG_DRUG Nuflor gold ChemIDplus Sch 25298 ChemIDplus Sch-25298 ChemIDplus florfenicol KEGG_DRUG Any dicarboximide antifungal agent used as a fungicide. chebi_ontology dicarboximide fungicides CHEBI:87195 dicarboximide fungicide CHEBI:87195 dicarboximide fungicides ChEBI A dicarboximide fungicide in which the nitrogen of the dicarboximide group is substituted by a dichlorophenyl group. chebi_ontology dichlorophenyl dicarboximide fungicides CHEBI:87197 dichlorophenyl dicarboximide fungicide CHEBI:87197 dichlorophenyl dicarboximide fungicides ChEBI A dicarboximide fungicide whose structure contains a phthalimide derivative. chebi_ontology phthalimide fungicides CHEBI:87198 phthalimide fungicide CHEBI:87198 phthalimide fungicides ChEBI A compound that has significant antifungal properties whose structure contains a dicarboximide moiety. chebi_ontology dicarboximide antifungal agents CHEBI:87200 dicarboximide antifungal agent CHEBI:87200 dicarboximide antifungal agents ChEBI A member of the class of pyrimidines that has significant antifungal properties. chebi_ontology pyrimidine antifungal agents CHEBI:87204 pyrimidine antifungal agent CHEBI:87204 pyrimidine antifungal agents ChEBI Any pyrimidine antifungal agent that has been used for the treatment of fungal infections in humans or animals. chebi_ontology pyrimidine antifungal drugs CHEBI:87205 pyrimidine antifungal drug CHEBI:87205 pyrimidine antifungal drugs ChEBI Any pyrimidine antifungal agent that has been used as a fungicide. chebi_ontology pyrimidine fungicides CHEBI:87207 pyrimidine fungicide CHEBI:87207 pyrimidine fungicides ChEBI Any pyrimidine fungicide in which the pyrimidine ring is substituted by the nitrogen of an aniline moiety. chebi_ontology anilinopyrimidine fungicides CHEBI:87208 anilinopyrimidine fungicide CHEBI:87208 anilinopyrimidine fungicides ChEBI A mixture of cyclic polypeptide streptogramin antibiotics produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. The two major components are virginiamycin M1 (also known as pristinamycin IIA) and virginiamycin S1. Virginiamycin has been widely used as a growth promotion agent in livestock and has been to have bacteriostatic activity against Gram-positive organisms such as staphylococci and streptococci. CAS:11006-76-1 HMDB:HMDB0030520 KEGG:D06311 PMID:1493906 PMID:21676560 PMID:25874109 PMID:2907457 PMID:39060 PMID:4568014 PMID:8851577 Reaxys:13135027 Wikipedia:Virginiamycin chebi_ontology virginiamicina virginiamycin virginiamycine virginiamycins virginiamycinum CHEBI:87209 virginiamycin CHEBI:87209 CAS:11006-76-1 ChemIDplus CAS:11006-76-1 KEGG DRUG PMID:1493906 Europe PMC PMID:21676560 Europe PMC PMID:25874109 Europe PMC PMID:2907457 Europe PMC PMID:39060 Europe PMC PMID:4568014 Europe PMC PMID:8851577 Europe PMC Reaxys:13135027 Reaxys virginiamicina WHO_MedNet virginiamycin WHO_MedNet virginiamycine WHO_MedNet virginiamycins ChEBI virginiamycinum WHO_MedNet An organonitrogen heterocyclic antibiotic containing a quinolone (or quinolone-like) moiety and which have a fluorine atom attached to the central ring system. PMID:24947193 PMID:25226071 PMID:8386356 chebi_ontology fluoroquinolone antibiotics CHEBI:87211 fluoroquinolone antibiotic CHEBI:87211 PMID:24947193 Europe PMC PMID:25226071 Europe PMC PMID:8386356 Europe PMC fluoroquinolone antibiotics ChEBI A class of sulfonamides whose members generally have bacteriostatic antibiotic properties. PMID:24443047 PMID:24928456 PMID:25064257 PMID:25796473 PMID:26177406 Wikipedia:Sulfonamide_(medicine) chebi_ontology sulfonamide antibiotics sulfonamide antimicrobial agent sulfonamide antimicrobial agents sulphonamide antibiotic sulphonamide antibiotics CHEBI:87228 sulfonamide antibiotic CHEBI:87228 PMID:24443047 Europe PMC PMID:24928456 Europe PMC PMID:25064257 Europe PMC PMID:25796473 Europe PMC PMID:26177406 Europe PMC sulfonamide antibiotics ChEBI sulfonamide antimicrobial agent ChEBI sulfonamide antimicrobial agents ChEBI sulphonamide antibiotic ChEBI sulphonamide antibiotics ChEBI A member of the class of furans in which the furan ring is substituted by a nitro group and which also has significant antibiotic properties. AGR:IND44688035 PMID:15776153 PMID:16999120 PMID:17691006 PMID:23785991 PMID:25437357 Wikipedia:Nitrofuran chebi_ontology nitrofuran antibiotics nitrofuran antimicrobial agent nitrofuran antimicrobial agents CHEBI:87230 nitrofuran antibiotic CHEBI:87230 AGR:IND44688035 Europe PMC PMID:15776153 Europe PMC PMID:16999120 Europe PMC PMID:17691006 Europe PMC PMID:23785991 Europe PMC PMID:25437357 Europe PMC nitrofuran antibiotics ChEBI nitrofuran antimicrobial agent ChEBI nitrofuran antimicrobial agents ChEBI 0 C53H67N9O10S.C34H50N4O9S InChI=1S/C53H67N9O10S.C34H50N4O9S/c1-6-37-50(68)61-23-11-14-38(61)51(69)59(5)40(26-32-16-18-36(19-17-32)58(3)4)52(70)62-28-35(30-73-43-29-60-24-20-33(43)21-25-60)42(64)27-39(62)47(65)57-45(34-12-8-7-9-13-34)53(71)72-31(2)44(48(66)55-37)56-49(67)46-41(63)15-10-22-54-46;1-7-37(8-2)16-17-48(44,45)28-13-15-38-31(28)34(43)47-32(22(3)4)24(6)11-12-29(41)35-14-9-10-23(5)18-25(39)19-26(40)20-30-36-27(21-46-30)33(38)42/h7-10,12-13,15-19,22,31,33,35,37-40,43-45,63H,6,11,14,20-21,23-30H2,1-5H3,(H,55,66)(H,56,67)(H,57,65);9-12,18,21-22,24-25,28,31-32,39H,7-8,13-17,19-20H2,1-6H3,(H,35,41)/b;10-9+,12-11+,23-18+/t31-,35?,37-,38+,39?,40+,43-,44+,45+;24-,25-,28-,31?,32-/m11/s1 PPKJUHVNTMYXOD-HVWWIRKTSA-N 1713.071 1711.80301 CCN(CC)CCS(=O)(=O)[C@@H]1CCN2C1C(=O)O[C@H](C(C)C)[C@H](C)\C=C\C(=O)NC\C=C\C(C)=C\[C@@H](O)CC(=O)Cc1nc(co1)C2=O.CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@@H](NC(=O)C2CC(=O)C(CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(cc2)N(C)C)N(C)C(=O)[C@@H]2CCCN2C1=O)c1ccccc1 CAS:126602-89-9 KEGG:C08034 KEGG:D00854 Quinupristin-dalfopristin chebi_ontology CHEBI:8733 Quinupristin-dalfopristin CHEBI:8733 CAS:126602-89-9 KEGG COMPOUND Quinupristin-dalfopristin KEGG_COMPOUND An organic cation obtained by protonation of the six amino groups of framycetin; major species at pH 7.3. +6 C23H52N6O13 InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/p+6/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1 PGBHMTALBVVCIT-VCIWKGPPSA-T 620.692 620.35594 [C@@H]1([C@H]([C@@H]([C@@H]([NH3+])[C@@H](O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)O[C@H]3[C@@H]([C@H](C[C@H]([C@@H]3O)[NH3+])[NH3+])O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C[NH3+])O)O)[NH3+])O1)O)O)C[NH3+] MetaCyc:CPD-14142 PMID:25230155 (1R,2R,3S,4R,6S)-4,6-bis(azaniumyl)-2-({3-O-[2,6-bis(azaniumyl)-2,6-dideoxy-beta-L-idopyranosyl]-beta-D-ribofuranosyl}oxy)-3-hydroxycyclohexyl 2,6-bis[(azaniumyl)]-2,6-dideoxy-alpha-D-glucopyranoside chebi_ontology neomycin B CHEBI:87835 framycetin(6+) CHEBI:87835 MetaCyc:CPD-14142 SUBMITTER PMID:25230155 SUBMITTER (1R,2R,3S,4R,6S)-4,6-bis(azaniumyl)-2-({3-O-[2,6-bis(azaniumyl)-2,6-dideoxy-beta-L-idopyranosyl]-beta-D-ribofuranosyl}oxy)-3-hydroxycyclohexyl 2,6-bis[(azaniumyl)]-2,6-dideoxy-alpha-D-glucopyranoside IUPAC neomycin B UniProt Any organic amino compound that contains two or more amino groups. Wikipedia:Polyamine chebi_ontology polyamines CHEBI:88061 polyamine CHEBI:88061 polyamines ChEBI Any metal which causes the onset of an allergic reaction. chebi_ontology allergenic metal allergenic metals metal allergens CHEBI:88184 metal allergen CHEBI:88184 allergenic metal ChEBI allergenic metals ChEBI metal allergens ChEBI Any penicillin which causes the onset of an allergic reaction. chebi_ontology allergenic penicillin allergenic penicillin compound allergenic penicillin compounds allergenic penicillins penicillin allergens CHEBI:88187 penicillin allergen CHEBI:88187 allergenic penicillin ChEBI allergenic penicillin compound ChEBI allergenic penicillin compounds ChEBI allergenic penicillins ChEBI penicillin allergens ChEBI Any drug which causes the onset of an allergic reaction. chebi_ontology allergenic drug CHEBI:88188 drug allergen CHEBI:88188 allergenic drug ChEBI Any beta-lactam antibiotic which causes the onset of an allergic reaction. chebi_ontology allergenic beta-lactam antibiotic allergenic beta-lactam antibiotics beta-lactam antibiotic allergens CHEBI:88225 beta-lactam antibiotic allergen CHEBI:88225 allergenic beta-lactam antibiotic ChEBI allergenic beta-lactam antibiotics ChEBI beta-lactam antibiotic allergens ChEBI Any ionophore capable of transportation of potassium ions across membranes. PMID:11841304 chebi_ontology potassium ionophores CHEBI:88227 potassium ionophore CHEBI:88227 PMID:11841304 Europe PMC potassium ionophores ChEBI An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate. 0 C12H25NaO4S InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1 DBMJMQXJHONAFJ-UHFFFAOYSA-M 288.38027 288.13712 [Na+].CCCCCCCCCCCCOS([O-])(=O)=O Beilstein:3599286 CAS:151-21-3 DrugBank:DB00815 Gmelin:117722 KEGG:C11166 KEGG:D01045 PMID:29079364 Sodium dodecyl sulfate chebi_ontology SDS SLS Sodium lauryl sulfate sodium dodecyl sulphate sodium dodecylsulfate sodium lauryl sulphate CHEBI:8984 sodium dodecyl sulfate CHEBI:8984 Beilstein:3599286 Beilstein CAS:151-21-3 ChemIDplus CAS:151-21-3 KEGG COMPOUND Gmelin:117722 Gmelin PMID:29079364 Europe PMC Sodium dodecyl sulfate KEGG_COMPOUND SDS KEGG_COMPOUND SLS ChemIDplus Sodium lauryl sulfate KEGG_COMPOUND sodium dodecyl sulphate ChemIDplus sodium dodecylsulfate ChemIDplus sodium lauryl sulphate ChemIDplus A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors. CHEBI:189678 Wikipedia:Receptor_modulator chebi_ontology receptor modulators CHEBI:90710 receptor modulator CHEBI:90710 receptor modulators ChEBI Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3. 0 C4H6N2O3R2 130.102 130.03784 [NH3+]C(C(NC(C([O-])=O)*)=O)* chebi_ontology a dipeptide CHEBI:90799 dipeptide zwitterion CHEBI:90799 a dipeptide UniProt A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3. -1 CO2R 44.010 43.98983 *C([O-])=O chebi_ontology an aromatic carboxylate CHEBI:91007 aromatic carboxylate CHEBI:91007 an aromatic carboxylate UniProt A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. 0 C51H79NO13 InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 914.17190 913.55514 [H][C@]1(CC[C@@H](O)[C@@H](C1)OC)C[C@@H](C)[C@]1([H])CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@]2([H])CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@@]2([H])C(=O)O1)OC CHEBI:45276 CHEBI:67812 CAS:53123-88-9 DrugBank:DB00877 Drug_Central:2446 HMDB:HMDB0015015 KEGG:C07909 KEGG:D00753 KNApSAcK:C00018055 LIPID_MAPS_instance:LMPK06000003 PDBeChem:RAP PMID:19587680 PMID:22960739 PMID:22981852 PMID:22984623 PMID:24341993 PMID:24409289 Reaxys:5848501 Wikipedia:Rapamycin (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone Sirolimus chebi_ontology (-)-Rapamycin (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone Antibiotic AY 22989 Rapamune rapamycin sirolimus sirolimusum CHEBI:9168 sirolimus CHEBI:9168 CAS:53123-88-9 ChemIDplus CAS:53123-88-9 KEGG COMPOUND Drug_Central:2446 DrugCentral LIPID_MAPS_instance:LMPK06000003 LIPID MAPS PMID:19587680 Europe PMC PMID:22960739 Europe PMC PMID:22981852 Europe PMC PMID:22984623 Europe PMC PMID:24341993 Europe PMC PMID:24409289 Europe PMC Reaxys:5848501 Reaxys (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone IUPAC Sirolimus KEGG_COMPOUND (-)-Rapamycin ChemIDplus (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone IUPAC Antibiotic AY 22989 DrugBank Rapamune DrugBank rapamycin ChEBI sirolimus WHO_MedNet sirolimusum WHO_MedNet 0 C19H22F2N4O3 InChI=1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+ DZZWHBIBMUVIIW-DTORHVGOSA-N 392.39980 392.16600 C[C@H]1CN(C[C@@H](C)N1)c1c(F)c(N)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1 Beilstein:3658018 CAS:110871-86-8 DrugBank:DB01208 Drug_Central:2466 KEGG:C07662 KEGG:D00590 LINCS:LSM-5251 Wikipedia:Sparfloxacin 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Sparfloxacin chebi_ontology cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid CHEBI:9212 sparfloxacin CHEBI:9212 Beilstein:3658018 ChemIDplus CAS:110871-86-8 ChemIDplus CAS:110871-86-8 KEGG COMPOUND Drug_Central:2466 DrugCentral 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid IUPAC Sparfloxacin KEGG_COMPOUND cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid KEGG_COMPOUND A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. 0 C14H24N2O7 InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1 UNFWWIHTNXNPBV-WXKVUWSESA-N 332.34960 332.15835 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O CHEBI:45551 CAS:1695-77-8 DrugBank:DB00919 Drug_Central:2468 HMDB:HMDB0015055 KEGG:C02078 KEGG:D08526 LINCS:LSM-5298 PDBeChem:SCM PMID:23183436 PMID:23847609 PMID:24020122 PMID:24402501 PMID:24503209 PMID:30033166 PMID:32116136 Patent:US4203903 Patent:WO2005041984 Reaxys:2171701 Wikipedia:Spectinomycin (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one chebi_ontology Antibiotic 2233wp espectinomicina spectinomycin spectinomycine spectinomycinum CHEBI:9215 spectinomycin CHEBI:9215 CAS:1695-77-8 ChemIDplus CAS:1695-77-8 KEGG COMPOUND Drug_Central:2468 DrugCentral PMID:23183436 Europe PMC PMID:23847609 Europe PMC PMID:24020122 Europe PMC PMID:24402501 Europe PMC PMID:24503209 Europe PMC PMID:30033166 Europe PMC PMID:32116136 Europe PMC Reaxys:2171701 Reaxys (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one IUPAC Antibiotic 2233wp ChemIDplus espectinomicina DrugBank spectinomycin KEGG_DRUG spectinomycine DrugBank spectinomycinum DrugBank The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes. 0 C18H35NO2 InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 PUYXTUJWRLOUCW-UHFFFAOYSA-N 297.47600 297.26678 CCCN(CC)CC1COC2(CCC(CC2)C(C)(C)C)O1 CHEBI:546779 AGR:IND43667533 CAS:118134-30-8 KEGG:C11124 PMID:16366700 PMID:16526469 PMID:17804411 PMID:19733892 PMID:20060629 PPDB:599 Patent:DE3735555 Patent:US4851405 Pesticides:spiroxamine Reaxys:11342560 N-[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]-N-ethylpropan-1-amine Spiroxamine chebi_ontology (8-tert-Butyl-1,4-dioxa-spiro[4.5]dec-2-ylmethyl)-ethyl-propyl-amine 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro(4.5)decane-2-methanamine Impulse KWG4168 Prosper CHEBI:9242 spiroxamine CHEBI:9242 AGR:IND43667533 Europe PMC CAS:118134-30-8 ChemIDplus CAS:118134-30-8 KEGG COMPOUND PMID:16366700 Europe PMC PMID:16526469 Europe PMC PMID:17804411 ChEMBL PMID:19733892 Europe PMC PMID:20060629 Europe PMC Pesticides:spiroxamine Alan Wood's Pesticides Reaxys:11342560 Reaxys N-[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]-N-ethylpropan-1-amine IUPAC Spiroxamine KEGG_COMPOUND (8-tert-Butyl-1,4-dioxa-spiro[4.5]dec-2-ylmethyl)-ethyl-propyl-amine ChEMBL 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro(4.5)decane-2-methanamine ChEBI Impulse ChEBI KWG4168 KEGG_COMPOUND Prosper ChEBI 0 C8H11NO5S InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1 FKENQMMABCRJMK-RITPCOANSA-N 233.24200 233.03579 [H][C@@]12CC(=O)N1[C@@H](C(O)=O)C(C)(C)S2(=O)=O Beilstein:4192832 CAS:68373-14-8 CAS:69388-84-7 Drug_Central:2492 HMDB:HMDB0258566 KEGG:C07770 KEGG:D08533 LINCS:LSM-5553 PDBeChem:0RN PMID:11220688 PMID:17422866 PMID:17422867 PMID:17630699 PMID:18611714 PMID:22974281 PMID:37603677 PMID:37679343 PMID:8557585 PMID:8935129 Patent:BE867859 Patent:US4234579 Wikipedia:Sulbactam 2,2-dimethyl-1,1-dioxidopenam-3alpha-carboxylic acid chebi_ontology (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide CP 45899 CP-45899 CP45899 penicillanic acid 1,1-dioxide penicillanic acid sulfone sulbactam sulbactamum CHEBI:9321 sulbactam CHEBI:9321 Beilstein:4192832 Beilstein CAS:68373-14-8 ChemIDplus CAS:68373-14-8 KEGG COMPOUND CAS:69388-84-7 KEGG COMPOUND Drug_Central:2492 DrugCentral PMID:11220688 Europe PMC PMID:17422866 Europe PMC PMID:17422867 Europe PMC PMID:17630699 Europe PMC PMID:18611714 Europe PMC PMID:22974281 Europe PMC PMID:37603677 Europe PMC PMID:37679343 Europe PMC PMID:8557585 Europe PMC PMID:8935129 Europe PMC 2,2-dimethyl-1,1-dioxidopenam-3alpha-carboxylic acid IUPAC (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide ChemIDplus (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide IUPAC CP 45899 DrugBank CP-45899 DrugBank CP45899 DrugBank penicillanic acid 1,1-dioxide ChEBI penicillanic acid sulfone ChEBI sulbactam WHO_MedNet sulbactamum WHO_MedNet A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. 0 C21H25N InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+ DOMXUEMWDBAQBQ-WEVVVXLNSA-N 291.42990 291.19870 CN(C\C=C\C#CC(C)(C)C)Cc1cccc2ccccc12 CAS:91161-71-6 DrugBank:DB00857 Drug_Central:2597 HMDB:HMDB0014995 KEGG:C08079 KEGG:D02375 MetaCyc:CPD-10571 PMID:23750489 PMID:23802806 PMID:23841559 PMID:23895037 PMID:24126579 PMID:24352873 PMID:24389279 PMID:24410098 PMID:24447130 PMID:24452843 PMID:24477462 PMID:24490976 PMID:24497012 PMID:24533442 PMID:24563892 PMID:24576265 PMID:24581620 PMID:24588014 Reaxys:4256376 Wikipedia:Terbinafine (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine terbinafine chebi_ontology (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine terbinafina terbinafine terbinafinum CHEBI:9448 terbinafine CHEBI:9448 CAS:91161-71-6 ChemIDplus CAS:91161-71-6 KEGG COMPOUND Drug_Central:2597 DrugCentral PMID:23750489 Europe PMC PMID:23802806 Europe PMC PMID:23841559 Europe PMC PMID:23895037 Europe PMC PMID:24126579 Europe PMC PMID:24352873 Europe PMC PMID:24389279 Europe PMC PMID:24410098 Europe PMC PMID:24447130 Europe PMC PMID:24452843 Europe PMC PMID:24477462 Europe PMC PMID:24490976 Europe PMC PMID:24497012 Europe PMC PMID:24533442 Europe PMC PMID:24563892 Europe PMC PMID:24576265 Europe PMC PMID:24581620 Europe PMC PMID:24588014 Europe PMC Reaxys:4256376 Reaxys (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine IUPAC terbinafine WHO_MedNet (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ChemIDplus (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine ChemIDplus terbinafina WHO_MedNet terbinafine KEGG_DRUG terbinafinum WHO_MedNet 0 C14H9Cl3N2OS InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19) NQPDXQQQCQDHHW-UHFFFAOYSA-N 359.659 357.95012 CSC1=NC2=CC(=C(C=C2N1)Cl)OC3=C(C(=CC=C3)Cl)Cl CAS:68786-66-3 Drug_Central:2734 LINCS:LSM-5875 VSDB:1773 chebi_ontology fasinex CHEBI:94759 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole CHEBI:94759 CAS:68786-66-3 DrugCentral Drug_Central:2734 DrugCentral fasinex DrugCentral A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group. 0 C15H16N2O6S2 InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1 OHKOGUYZJXTSFX-KZFFXBSXSA-N 384.42700 384.04498 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@]([H])(C(O)=O)c1ccsc1)C(O)=O Beilstein:6009447 CAS:34787-01-4 DrugBank:DB01607 Drug_Central:2656 KEGG:C07139 KEGG:D08593 PMID:12569987 PMID:1384868 PMID:23775821 PMID:24369293 PMID:29017833 Patent:BE646991 Patent:US3282926 Reaxys:6009447 Wikipedia:Ticarcillin 6beta-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-2,2-dimethylpenam-3alpha-carboxylic acid chebi_ontology (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid alpha-carboxy-3-thienylmethylpenicillin ticarcilina ticarcillin ticarcilline ticarcillinum CHEBI:9587 ticarcillin CHEBI:9587 Beilstein:6009447 Beilstein CAS:34787-01-4 ChemIDplus CAS:34787-01-4 KEGG COMPOUND Drug_Central:2656 DrugCentral PMID:12569987 Europe PMC PMID:1384868 Europe PMC PMID:23775821 Europe PMC PMID:24369293 Europe PMC PMID:29017833 Europe PMC Reaxys:6009447 Reaxys 6beta-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-2,2-dimethylpenam-3alpha-carboxylic acid IUPAC (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid IUPAC alpha-carboxy-3-thienylmethylpenicillin Patent ticarcilina ChemIDplus ticarcillin ChemIDplus ticarcilline ChemIDplus ticarcillinum ChemIDplus A racemate comprising equal amounts of (R)- and (S)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in crops. 0 C14H16ClN3O2 293.74900 293.09310 CAS:43121-43-3 KEGG:C11156 MetaCyc:CPD-4061 PMID:23419873 PMID:23876258 PMID:24342051 PMID:24531054 PMID:24846121 PMID:24962053 PMID:25011125 Pesticides:triadimefon Reaxys:619231 Wikipedia:Triadimefon rac-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one chebi_ontology (+-)-triadimefon (RS)-triadimefon 1-(1,2,4-Triazoyl-1)-1-(4-chloro-phenoxy)-3,3-dimethylbutanone 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-one 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butanone 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone rac-triadimefon racemic triadimefon triadimefone CHEBI:9665 triadimefon CHEBI:9665 CAS:43121-43-3 ChemIDplus CAS:43121-43-3 KEGG COMPOUND CAS:43121-43-3 NIST Chemistry WebBook PMID:23419873 Europe PMC PMID:23876258 Europe PMC PMID:24342051 Europe PMC PMID:24531054 Europe PMC PMID:24846121 Europe PMC PMID:24962053 Europe PMC PMID:25011125 Europe PMC Pesticides:triadimefon Alan Wood's Pesticides Reaxys:619231 Reaxys rac-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one IUPAC (+-)-triadimefon ChEBI (RS)-triadimefon ChEBI 1-(1,2,4-Triazoyl-1)-1-(4-chloro-phenoxy)-3,3-dimethylbutanone ChemIDplus 1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-one ChemIDplus 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butanone NIST_Chemistry_WebBook 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone Alan_Wood's_Pesticides rac-triadimefon ChEBI racemic triadimefon ChEBI triadimefone MetaCyc A mixture of 4-alkyl-2,6-dimethylmorpholines, where 'alkyl' is a mixture of C11 to C14 homologues of which 60-70% is tridecyl. A systemic fungicide, it is no longer approved for use within the European Union. AGR:IND84012971 AGR:IND93043841 CAS:81412-43-3 HMDB:HMDB0031810 KEGG:C11285 PMID:15092713 PMID:1841872 PMID:6740510 Patent:BE614214 Patent:US3468885 Pesticides:tridemorph Reaxys:8389338 Wikipedia:Tridemorph Tridemorph chebi_ontology BAS 2203F Calixin tridemorphe CHEBI:9700 tridemorph CHEBI:9700 AGR:IND84012971 Europe PMC AGR:IND93043841 Europe PMC CAS:81412-43-3 Alan Wood's Pesticides CAS:81412-43-3 ChemIDplus PMID:15092713 Europe PMC PMID:1841872 Europe PMC PMID:6740510 Europe PMC Pesticides:tridemorph Alan Wood's Pesticides Reaxys:8389338 Reaxys Tridemorph KEGG_COMPOUND BAS 2203F ChemIDplus Calixin ChemIDplus tridemorphe ChEBI A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure. 0 C20H15F3N4O3 InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+ WVPSKSLAZQPAKQ-CDMJZVDBSA-N 416.35330 416.10962 N[C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F CAS:147059-72-1 DrugBank:DB00685 Drug_Central:2777 HMDB:HMDB0014823 KEGG:C07664 KEGG:D08654 PMID:20022474 PMID:20462743 PMID:20538741 PMID:20655887 PMID:21151465 PMID:22305082 PMID:23727874 PMID:24097668 PMID:24525298 Reaxys:8172628 Wikipedia:Trovafloxacin 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid chebi_ontology trovafloxacin trovafloxacine trovafloxacino trovafloxacinum CHEBI:9763 trovafloxacin CHEBI:9763 CAS:147059-72-1 ChemIDplus CAS:147059-72-1 KEGG COMPOUND Drug_Central:2777 DrugCentral PMID:20022474 Europe PMC PMID:20462743 Europe PMC PMID:20538741 Europe PMC PMID:20655887 Europe PMC PMID:21151465 Europe PMC PMID:22305082 Europe PMC PMID:23727874 Europe PMC PMID:24097668 Europe PMC PMID:24525298 Europe PMC Reaxys:8172628 Reaxys 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid IUPAC trovafloxacin KEGG_DRUG trovafloxacine WHO_MedNet trovafloxacino WHO_MedNet trovafloxacinum WHO_MedNet A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. 0 C27H38N2O4 454.60160 454.28316 Beilstein:2825000 CAS:52-53-9 DrugBank:DB00661 HMDB:HMDB0001850 KEGG:C07188 KEGG:D02356 PMID:11142488 PMID:11389609 PMID:11454724 PMID:11975770 PMID:12454681 PMID:14681337 PMID:16545584 PMID:17525564 PMID:17724247 PMID:18093581 PMID:18337499 PMID:19125880 PMID:24532601 PMID:24577794 PMID:25297337 PMID:25331694 PMID:25650380 PMID:25968157 PMID:26046259 PMID:26504804 PMID:26553277 PMID:26567612 PMID:8861548 Reaxys:2825000 Wikipedia:Verapamil Verapamil rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile chebi_ontology verapamil verapamilo verapamilum CHEBI:9948 verapamil CHEBI:9948 Beilstein:2825000 Beilstein CAS:52-53-9 ChemIDplus CAS:52-53-9 KEGG COMPOUND CAS:52-53-9 NIST Chemistry WebBook PMID:11142488 Europe PMC PMID:11389609 Europe PMC PMID:11454724 Europe PMC PMID:11975770 Europe PMC PMID:12454681 Europe PMC PMID:14681337 Europe PMC PMID:16545584 Europe PMC PMID:17525564 Europe PMC PMID:17724247 Europe PMC PMID:18093581 Europe PMC PMID:18337499 Europe PMC PMID:19125880 Europe PMC PMID:24532601 Europe PMC PMID:24577794 Europe PMC PMID:25297337 Europe PMC PMID:25331694 Europe PMC PMID:25650380 Europe PMC PMID:25968157 Europe PMC PMID:26046259 Europe PMC PMID:26504804 Europe PMC PMID:26553277 Europe PMC PMID:26567612 Europe PMC PMID:8861548 Europe PMC Reaxys:2825000 Reaxys Verapamil KEGG_COMPOUND rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile IUPAC verapamil ChemIDplus verapamil WHO_MedNet verapamilo ChemIDplus verapamilum ChemIDplus A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp. CAS:50471-44-8 KEGG:C10981 PMID:24072643 PMID:24333988 PMID:24388192 PMID:24497202 PMID:24636578 PMID:24995616 PMID:25019461 PMID:25051444 PMID:25111804 PMID:25161548 PMID:25190560 PMID:25324206 Pesticides:vinclozolin Reaxys:1080192 Reaxys:8331312 Wikipedia:Vinclozolin rac-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione chebi_ontology (+-)-vinclozolin (RS)-vinclozolin 3-(3,5-Dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione 3-(3,5-Dichlorophenyl)-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione N-3,5-Dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione Vinchlozoline Vinclozoline rac-vinclozolin racemic vinclozolin CHEBI:9986 vinclozolin CHEBI:9986 CAS:50471-44-8 ChemIDplus CAS:50471-44-8 KEGG COMPOUND CAS:50471-44-8 NIST Chemistry WebBook PMID:24072643 Europe PMC PMID:24333988 Europe PMC PMID:24388192 Europe PMC PMID:24497202 Europe PMC PMID:24636578 Europe PMC PMID:24995616 Europe PMC PMID:25019461 Europe PMC PMID:25051444 Europe PMC PMID:25111804 Europe PMC PMID:25161548 Europe PMC PMID:25190560 Europe PMC PMID:25324206 Europe PMC Pesticides:vinclozolin Alan Wood's Pesticides Reaxys:1080192 Reaxys Reaxys:8331312 Reaxys rac-3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione IUPAC (+-)-vinclozolin ChEBI (RS)-vinclozolin ChEBI 3-(3,5-Dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione ChemIDplus 3-(3,5-Dichlorophenyl)-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione ChemIDplus N-3,5-Dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione NIST_Chemistry_WebBook Vinchlozoline ChemIDplus Vinclozoline ChemIDplus rac-vinclozolin ChEBI racemic vinclozolin ChEBI A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. 0 C28H35N3O7 InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1 DAIKHDNSXMZDCU-FQTGFAPKSA-N 525.59340 525.24750 CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c2coc(CC(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@H]1C)n2 CHEBI:46395 CAS:21411-53-0 DrugBank:DB01669 KEGG:C11299 PDBeChem:VIR PMID:15480455 PMID:24324222 PMID:24687494 PMID:25223995 PMID:3096930 PMID:5905315 Reaxys:71867 Wikipedia:Pristinamycin_IIA (3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone chebi_ontology Mikamycin A Ostreogrycin a Streptogramin A Virginiamycin M1 Virginiamycin factor M1 CHEBI:9997 pristinamycin IIA CHEBI:9997 CAS:21411-53-0 ChemIDplus CAS:21411-53-0 KEGG COMPOUND PMID:15480455 Europe PMC PMID:24324222 Europe PMC PMID:24687494 Europe PMC PMID:25223995 Europe PMC PMID:3096930 Europe PMC PMID:5905315 Europe PMC Reaxys:71867 Reaxys (3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone IUPAC Mikamycin A KEGG_COMPOUND Ostreogrycin a ChemIDplus Streptogramin A KEGG_COMPOUND Virginiamycin M1 KEGG_COMPOUND Virginiamycin factor M1 ChemIDplus CL:0000000 A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. A material entity that has a plasma membrane and results from cellular division. CALOHA:TS-2035 FBbt:00007002 FMA:68646 GO:0005623 KUPO:0000002 MESH:D002477 VHOG:0001533 WBbt:0004017 XAO:0003012 CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc. The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism. cell cell A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CARO:mah CL:0000151 A cell that specializes in controlled release of one or more substances. BTO:0003659 FMA:86916 secretory cell A cell that specializes in controlled release of one or more substances. GOC:tfm ISBN:0721662544 CL:0000154 protein secreting cell CL:0000225 A cell that lacks a nucleus. FMA:68647 non-nucleated cell anucleate cell A cell that lacks a nucleus. FB:ma CL:0000226 A cell with a single nucleus. single nucleate cell A cell with a single nucleus. FB:ma GOC:tfm CL:0000227 binucleate cell CL:0000228 A cell with more than one nucleus. AEO:0000203 WBbt:0008074 syncitium syncytial cell syncytium multinucleate cell A cell with more than one nucleus. FB:ma CL:0000255 MESH:D005057 eukaryotic cell CL:0000521 fungal cell CL:0000596 CL:0000605 CL:0001061 A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. 2017-01-30T18:53:32Z https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913 https://github.com/obophenotype/cell-ontology/issues/448 abnormal cell A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. GOC:add GOC:cg GOC:wdd CL:0002242 A cell containing at least one nucleus. 2010-09-07T03:32:33Z FMA:67513 nucleate cell A cell containing at least one nucleus. GOC:tfm CL:0011115 A cell that, by division or terminal differentiation, can give rise to other cell types. Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. precursor cell A cell that, by division or terminal differentiation, can give rise to other cell types. GOC:dos OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. https://github.com/geneontology/go-ontology/issues/27054 GO:0022414 GO:0019952 GO:0050876 Wikipedia:Reproduction reproductive physiological process biological_process GO:0000003 The reason for obsoletion is that this term is equivalent to reproductive process. obsolete reproduction reproduction true GO:0000003 OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. GOC:go_curators GOC:isa_complete GOC:jl ISBN:0198506732 The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. GOC:go_curators GOC:isa_complete GOC:jl ISBN:0198506732 The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. autophagic vacuole assembly autophagosome biosynthesis autophagosome formation PAS formation biological_process autophagic vacuole formation GO:0000045 autophagosome assembly GO:0000045 The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. GOC:autophagy PMID:9412464 autophagic vacuole assembly GOC:autophagy autophagic vacuole formation GOC:mah A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. Wikipedia:M_phase M-phase biological_process GO:0000279 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). M phase GO:0000279 A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. GOC:mtg_cell_cycle The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. biological_process karyokinesis GO:0000280 nuclear division GO:0000280 The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. GOC:mah Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). translation initiation ternary complex assembly biological_process GO:0001677 formation of translation initiation ternary complex GO:0001677 Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). GOC:hjd The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. biological_process GO:0001700 embryonic development via the syncytial blastoderm GO:0001700 The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. GOC:go_curators GOC:mtg_sensu Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. https://github.com/geneontology/go-ontology/issues/18737 biological_process GO:0002252 immune effector process GO:0002252 Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. GOC:add GO_REF:0000022 ISBN:0781735149 Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. Wikipedia:Immune_system biological_process GO:0002376 Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). immune system process GO:0002376 Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. GOC:add GO_REF:0000022 A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. biological_process GO:0002679 respiratory burst involved in defense response GO:0002679 A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GOC:add ISBN:0781735149 PMID:12789499 The controlled release of a peptide from a cell or a tissue. biological_process GO:0002790 peptide secretion GO:0002790 The controlled release of a peptide from a cell or a tissue. GOC:add Any process that modulates the frequency, rate, or extent of peptide secretion. biological_process GO:0002791 regulation of peptide secretion GO:0002791 Any process that modulates the frequency, rate, or extent of peptide secretion. GOC:add Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. down regulation of peptide secretion down-regulation of peptide secretion downregulation of peptide secretion inhibition of peptide secretion biological_process GO:0002792 negative regulation of peptide secretion GO:0002792 Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. GOC:add Any process that activates or increases the frequency, rate, or extent of peptide secretion. up regulation of peptide secretion up-regulation of peptide secretion upregulation of peptide secretion activation of peptide secretion stimulation of peptide secretion biological_process GO:0002793 positive regulation of peptide secretion GO:0002793 Any process that activates or increases the frequency, rate, or extent of peptide secretion. GOC:add A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. puberty biological_process reproductive developmental process GO:0003006 developmental process involved in reproduction GO:0003006 A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. GOC:dph GOC:isa_complete puberty GOC:dph reproductive developmental process GOC:dph GOC:tb A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. GO:0005554 molecular function molecular_function GO:0003674 Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. This is the same as GO molecular function gene product or complex activity molecular_function GO:0003674 A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. GOC:pdt Binding to a nucleic acid. GO:0000496 base pairing molecular_function GO:0003676 nucleic acid binding GO:0003676 Binding to a nucleic acid. GOC:jl Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0043566 plasmid binding molecular_function microtubule/chromatin interaction structure specific DNA binding structure-specific DNA binding GO:0003677 DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GOC:dph GOC:jl GOC:tb GOC:vw Binding to an RNA molecule or a portion thereof. GO:0000498 GO:0044822 Reactome:R-HSA-203922 base pairing with RNA molecular_function poly(A) RNA binding poly(A)-RNA binding poly-A RNA binding GO:0003723 RNA binding GO:0003723 Binding to an RNA molecule or a portion thereof. GOC:jl GOC:mah Reactome:R-HSA-203922 Exportin-5 recognizes 3' overhang of pre-miRNA Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Wikipedia:Enzyme enzyme activity molecular_function GO:0003824 catalytic activity GO:0003824 Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GOC:vw ISBN:0198506732 enzyme activity GOC:dph GOC:tb Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis. https://github.com/geneontology/go-ontology/issues/21612 GO:0004280 Reactome:R-HSA-9698929 Reactome:R-HSA-9838004 Reactome:R-HSA-9838081 Reactome:R-HSA-9838289 Reactome:R-HSA-9839059 Reactome:R-HSA-9839105 Reactome:R-HSA-9839113 Reactome:R-HSA-9839146 Reactome:R-HSA-9839751 molecular_function ATP-dependent proteolysis GO:0004176 ATP-dependent peptidase activity GO:0004176 Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis. GOC:mah Reactome:R-HSA-9698929 pPR-AP:pAP cleaves the MCP:pPR-AP:pAP Complex Reactome:R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins Reactome:R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins Reactome:R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins Reactome:R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) Reactome:R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins Reactome:R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins Reactome:R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins Reactome:R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins ATP-dependent proteolysis GOC:mah Catalysis of the hydrolysis of any O-glycosyl bond. GO:0016800 EC:3.2.1.- Reactome:R-HSA-5694563 Reactome:R-HSA-6786652 Reactome:R-HSA-9661820 O-glucosyl hydrolase activity molecular_function GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 Catalysis of the hydrolysis of any O-glycosyl bond. GOC:mah Reactome:R-HSA-5694563 ABHD10 hydrolyses MPAG Reactome:R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP Reactome:R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. EC:3.2.1.14 MetaCyc:3.2.1.14-RXN Reactome:R-HSA-6786421 molecular_function 1,4-beta-poly-N-acetylglucosaminidase activity beta-1,4-poly-N-acetyl glucosamidinase activity chitodextrinase activity poly-beta-glucosaminidase activity poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity GO:0004568 chitinase activity GO:0004568 Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. EC:3.2.1.14 GOC:bf GOC:kah GOC:pde PMID:11468293 Reactome:R-HSA-6786421 CHIA hydrolyses chitin 1,4-beta-poly-N-acetylglucosaminidase activity EC:3.2.1.14 beta-1,4-poly-N-acetyl glucosamidinase activity EC:3.2.1.14 chitodextrinase activity EC:3.2.1.14 poly-beta-glucosaminidase activity EC:3.2.1.14 poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity EC:3.2.1.14 Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. https://github.com/geneontology/go-ontology/issues/27621 GO:0005478 molecular_function carrier GO:0005215 Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules. transporter activity GO:0005215 Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. GOC:ai GOC:dgf The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. Wikipedia:Binding_(molecular) ligand molecular_function GO:0005488 Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children. binding GO:0005488 The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. GOC:ceb GOC:mah ISBN:0198506732 Binding to a protein. GO:0001948 GO:0045308 protein amino acid binding glycoprotein binding molecular_function GO:0005515 protein binding GO:0005515 Binding to a protein. GOC:go_curators A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 cell or subcellular entity cellular component cellular_component subcellular entity GO:0005575 Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. cellular_component GO:0005575 A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt subcellular entity NIF_Subcellular:nlx_subcell_100315 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. Wikipedia:Extracellular extracellular cellular_component GO:0005576 Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region GO:0005576 The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. GOC:go_curators A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. https://github.com/geneontology/go-ontology/issues/17776 Wikipedia:Intracellular internal to cell intracellular protoplasm cellular_component nucleocytoplasm protoplast GO:0005622 intracellular anatomical structure GO:0005622 A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. ISBN:0198506732 nucleocytoplasm GOC:mah protoplast GOC:mah A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. NIF_Subcellular:sao1702920020 Wikipedia:Cell_nucleus cell nucleus horsetail nucleus cellular_component GO:0005634 cell nucleus nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. GOC:go_curators horsetail nucleus GOC:al GOC:mah GOC:vw PMID:15030757 The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). GO:0005636 Wikipedia:Nuclear_envelope cellular_component GO:0005635 nuclear envelope GO:0005635 The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). ISBN:0198547684 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. https://github.com/geneontology/go-ontology/issues/23023 Wikipedia:Cytoplasm cellular_component GO:0005737 cytoplasm GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. ISBN:0198547684 A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. Wikipedia:Vacuole cellular_component vacuolar carboxypeptidase Y GO:0005773 vacuole GO:0005773 A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. GOC:mtg_sensu ISBN:0198506732 A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. NIF_Subcellular:sao8663416959 autophagic vacuole cellular_component initial autophagic vacuole GO:0005776 autophagosome GO:0005776 A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. GOC:autophagy ISBN:0198547684 PMID:11099404 autophagic vacuole NIF_Subcellular:sao8663416959 initial autophagic vacuole NIF_Subcellular:sao8663416959 An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. adiposome lipid body lipid particle cellular_component GO:0005811 Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers. lipid droplet GO:0005811 An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. GOC:mah GOC:tb The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0005887 GO:0005904 juxtamembrane NIF_Subcellular:sao1663586795 Wikipedia:Cell_membrane cell membrane cellular membrane cytoplasmic membrane plasmalemma bacterial inner membrane inner endospore membrane integral component of plasma membrane integral to plasma membrane plasma membrane lipid bilayer cellular_component GO:0005886 plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. ISBN:0716731363 cellular membrane NIF_Subcellular:sao6433132645 plasma membrane lipid bilayer GOC:mah The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. https://github.com/geneontology/go-ontology/issues/26298 Wikipedia:Cell_cortex ectoplasm cellular_component cell periphery peripheral cytoplasm GO:0005938 cell cortex GO:0005938 The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. GOC:mah ISBN:0815316194 A process in which chitin is transported to, or maintained in, a specific location. chitin localisation establishment and maintenance of chitin localization biological_process GO:0006033 chitin localization GO:0006033 A process in which chitin is transported to, or maintained in, a specific location. GOC:ai chitin localisation GOC:mah The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. alcohol metabolism biological_process GO:0006066 alcohol metabolic process GO:0006066 The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. ISBN:0198506732 The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. organic acid metabolism biological_process GO:0006082 organic acid metabolic process GO:0006082 The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. ISBN:0198506732 Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0055134 cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism nucleobase, nucleoside, nucleotide and nucleic acid metabolism biological_process nucleobase, nucleoside and nucleotide metabolic process nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0006139 nucleobase-containing compound metabolic process GO:0006139 Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. GOC:ai nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GOC:dph GOC:tb A process in which RNA is transported to, or maintained in, a specific location. RNA localisation establishment and maintenance of RNA localization biological_process GO:0006403 RNA localization GO:0006403 A process in which RNA is transported to, or maintained in, a specific location. GOC:ai RNA localisation GOC:mah The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0006416 GO:0006453 GO:0043037 Wikipedia:Translation_(genetics) protein anabolism protein biosynthesis protein biosynthetic process protein formation protein synthesis protein translation biological_process GO:0006412 translation GO:0006412 The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GOC:go_curators The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. GO:0006440 GO:0006454 biopolymerisation biopolymerization protein synthesis initiation translation initiation biological_process GO:0006413 translational initiation GO:0006413 The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. ISBN:019879276X The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. GO:0006442 GO:0006455 protein synthesis elongation translation elongation biological_process GO:0006414 translational elongation GO:0006414 The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. GOC:ems The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). GO:0006443 GO:0006456 protein synthesis termination translation termination translational complex disassembly biological_process GO:0006415 translational termination GO:0006415 The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). GOC:hjd ISBN:019879276X Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0006445 regulation of protein anabolism regulation of protein biosynthesis regulation of protein formation regulation of protein synthesis biological_process GO:0006417 regulation of translation GO:0006417 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GOC:isa_complete Any process that modulates the frequency, rate or extent of translational initiation. biological_process GO:0006446 regulation of translational initiation GO:0006446 Any process that modulates the frequency, rate or extent of translational initiation. GOC:go_curators Any process that modulates the frequency, rate, extent or accuracy of translational elongation. biological_process GO:0006448 regulation of translational elongation GO:0006448 Any process that modulates the frequency, rate, extent or accuracy of translational elongation. GOC:go_curators Any process that modulates the frequency, rate or extent of translational termination. biological_process GO:0006449 regulation of translational termination GO:0006449 Any process that modulates the frequency, rate or extent of translational termination. GOC:go_curators The process of introducing a phosphate group on to a protein. protein amino acid phosphorylation biological_process GO:0006468 protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein. GOC:hb protein amino acid phosphorylation GOC:bf The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. peptide metabolism biological_process GO:0006518 peptide metabolic process GO:0006518 The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. GOC:go_curators The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. https://github.com/geneontology/go-ontology/issues/17904 GO:0006519 cellular amino acid metabolic process cellular amino acid metabolism biological_process amino acid and derivative metabolism cellular amino acid and derivative metabolic process GO:0006520 amino acid metabolic process GO:0006520 The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. ISBN:0198506732 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. regulation of amino acid metabolism biological_process GO:0006521 regulation of cellular amino acid metabolic process GO:0006521 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. GOC:go_curators The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. Wikipedia:Lysine lysine metabolism biological_process GO:0006553 lysine metabolic process GO:0006553 The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. GOC:go_curators The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. Wikipedia:Lipid_metabolism lipid metabolism biological_process GO:0006629 lipid metabolic process GO:0006629 The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. GOC:ma The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. sesquiterpenoid metabolism biological_process GO:0006714 sesquiterpenoid metabolic process GO:0006714 The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. ISBN:0198547684 The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0016096 isoprenoid metabolism polyisoprenoid metabolic process polyisoprenoid metabolism polyterpene metabolic process polyterpene metabolism biological_process GO:0006720 isoprenoid metabolic process GO:0006720 The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. ISBN:0198547684 The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. terpenoid metabolism biological_process GO:0006721 terpenoid metabolic process GO:0006721 The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. ISBN:0198506732 The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. aromatic compound metabolism aromatic hydrocarbon metabolic process aromatic hydrocarbon metabolism biological_process GO:0006725 cellular aromatic compound metabolic process GO:0006725 The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. GOC:ai ISBN:0198506732 The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus. phosphorus metabolism biological_process GO:0006793 phosphorus metabolic process GO:0006793 The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). GOC:ai The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus. GOC:ai The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. phosphate metabolism biological_process phosphate metabolic process GO:0006796 phosphate-containing compound metabolic process GO:0006796 The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. GOC:ai The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. https://github.com/geneontology/go-ontology/issues/26424 nitrogen compound metabolism biological_process GO:0006807 nitrogen compound metabolic process GO:0006807 The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. GOC:jl ISBN:0198506732 The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. https://github.com/geneontology/go-ontology/issues/20292 jl 2012-12-13T16:25:32Z GO:0015457 GO:0015460 GO:0044765 biological_process single-organism transport GO:0006810 Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport GO:0006810 The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. GOC:dos GOC:dph GOC:jl GOC:mah The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process phosphate transport GO:0006817 phosphate ion transport GO:0006817 The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:krc The transport of substances that occurs outside cells. biological_process GO:0006858 extracellular transport GO:0006858 The transport of substances that occurs outside cells. GOC:go_curators The directed extracellular movement of amino acids. biological_process GO:0006860 extracellular amino acid transport GO:0006860 The directed extracellular movement of amino acids. GOC:ai The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006866 biological_process GO:0006865 amino acid transport GO:0006865 The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. GO:0032779 biological_process copper-induced intracellular protein transport GO:0006886 intracellular protein transport GO:0006886 The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. GOC:mah copper-induced intracellular protein transport GOC:al A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. https://github.com/geneontology/go-ontology/issues/24907 https://github.com/geneontology/go-ontology/issues/25268 GO:0016193 GO:0016196 GO:0098701 Wikipedia:Endocytosis endocytic import into cell vesicle endocytosis plasma membrane invagination biological_process nonselective vesicle endocytosis GO:0006897 endocytosis GO:0006897 A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. GOC:mah ISBN:0198506732 ISBN:0716731363 Wikipedia:Endocytosis The evagination of a membrane, resulting in formation of a vesicle. jl 2013-12-19T15:26:17Z GO:0006902 GO:1902591 membrane evagination vesicle biosynthesis vesicle formation biological_process nonselective vesicle assembly single organism membrane budding single-organism membrane budding vesicle budding GO:0006900 vesicle budding from membrane GO:0006900 The evagination of a membrane, resulting in formation of a vesicle. GOC:jid GOC:tb single organism membrane budding GOC:TermGenie The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. https://github.com/geneontology/go-ontology/issues/25541 GO:0016238 Wikipedia:Autophagy_(cellular) biological_process GO:0006914 autophagy GO:0006914 The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. GOC:autophagy ISBN:0198547684 PMID:11099404 PMID:29455577 PMID:9412464 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). biological_process response to abiotic stress response to biotic stress GO:0006950 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stress GO:0006950 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GOC:mah Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. GO:0002217 GO:0042829 defence response physiological defense response biological_process antimicrobial peptide activity defense/immunity protein activity GO:0006952 defense response GO:0006952 Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. GOC:go_curators Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. biological_process GO:0006955 immune response GO:0006955 Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. GOC:add GO_REF:0000022 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. https://github.com/geneontology/go-ontology/issues/27189 jl 2013-12-19T15:25:51Z GO:1902589 organelle organisation single organism organelle organization biological_process organelle organization and biogenesis single-organism organelle organization GO:0006996 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. organelle organization GO:0006996 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GOC:mah single organism organelle organization GOC:TermGenie organelle organization and biogenesis GOC:dph GOC:jl GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. GO:0048287 nuclear organisation nuclear organization biological_process nuclear morphology nuclear organization and biogenesis nucleus organization and biogenesis GO:0006997 nucleus organization GO:0006997 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. GOC:dph GOC:ems GOC:jl GOC:mah nuclear organization and biogenesis GOC:mah nucleus organization and biogenesis GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. nuclear envelope organisation biological_process nuclear envelope organization and biogenesis GO:0006998 nuclear envelope organization GO:0006998 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. GOC:dph GOC:ems GOC:jl GOC:mah nuclear envelope organisation GOC:mah nuclear envelope organization and biogenesis GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. plasma membrane organisation biological_process plasma membrane organization and biogenesis GO:0007009 plasma membrane organization GO:0007009 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. GOC:dph GOC:jl GOC:mah plasma membrane organization and biogenesis GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. cytoplasm organisation biological_process cytoplasm organization and biogenesis GO:0007028 cytoplasm organization GO:0007028 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GOC:curators GOC:dph GOC:jl GOC:mah cytoplasm organization and biogenesis GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. GO:0044086 vacuole organisation vacuolar assembly biological_process vacuole biogenesis vacuole organization and biogenesis GO:0007033 vacuole organization GO:0007033 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. GOC:mah vacuolar assembly GOC:mah vacuole biogenesis GOC:mah vacuole organization and biogenesis GOC:mah The directed movement of substances into, out of or within a vacuole. biological_process GO:0007034 vacuolar transport GO:0007034 The directed movement of substances into, out of or within a vacuole. GOC:ai The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. Wikipedia:Cell_cycle cell-division cycle biological_process GO:0007049 cell cycle GO:0007049 The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. GOC:go_curators GOC:mtg_cell_cycle The directed movement of the nucleus to a specific location within a cell. GO:0040023 establishment of position of nucleus nuclear movement nuclear positioning nucleus migration nucleus positioning positioning of nucleus biological_process establishment of cell nucleus localization establishment of localization of nucleus establishment of nucleus localisation establishment of nucleus localization GO:0007097 nuclear migration GO:0007097 The directed movement of the nucleus to a specific location within a cell. GOC:ai establishment of nucleus localisation GOC:mah The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. Wikipedia:Meiosis#Meiosis_I meiosis I nuclear division biological_process GO:0007127 meiosis I GO:0007127 The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. GOC:dph GOC:jl GOC:mtg_cell_cycle PMID:9334324 The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. biological_process GO:0007134 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). meiotic telophase I GO:0007134 The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. GOC:mtg_cell_cycle The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. Wikipedia:Meiosis#Meiosis_II meiosis II nuclear division biological_process GO:0007135 meiosis II GO:0007135 The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. GOC:dph GOC:mah ISBN:0198547684 The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). https://github.com/geneontology/go-ontology/issues/21234 biological_process GO:0007275 Note that this term was 'developmental process'. multicellular organism development GO:0007275 The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GOC:dph GOC:ems GOC:isa_complete GOC:tb Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. molecular_function GO:0008061 chitin binding GO:0008061 Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GOC:jl ISBN:0198506732 Any process in which a protein is transported to, or maintained in, a specific location. https://github.com/geneontology/go-ontology/issues/23112 GO:0008105 GO:0016249 GO:0034613 cellular protein localisation cellular protein localization protein localisation channel localizer activity biological_process asymmetric protein localisation asymmetric protein localization establishment and maintenance of asymmetric protein localization establishment and maintenance of protein localization GO:0008104 protein localization GO:0008104 Any process in which a protein is transported to, or maintained in, a specific location. GOC:ai cellular protein localisation GOC:mah protein localisation GOC:mah channel localizer activity GOC:mah asymmetric protein localisation GOC:mah A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. https://github.com/geneontology/go-ontology/issues/24968 jl 2012-09-19T15:05:24Z GO:0000004 GO:0007582 GO:0044699 Wikipedia:Biological_process biological process physiological process biological_process single organism process single-organism process GO:0008150 A biological process is an evolved process Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. biological process biological_process GO:0008150 A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. GOC:pdt The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. https://github.com/geneontology/go-ontology/issues/26424 jl 2012-10-17T15:46:40Z GO:0044236 GO:0044710 Wikipedia:Metabolism metabolism metabolic process resulting in cell growth metabolism resulting in cell growth multicellular organism metabolic process biological_process single-organism metabolic process GO:0008152 Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. metabolic process GO:0008152 The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. GOC:go_curators ISBN:0198547684 Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). https://github.com/geneontology/go-ontology/issues/24680 biological_process accidental cell death necrosis GO:0008219 This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death GO:0008219 Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). GOC:mah GOC:mtg_apoptosis PMID:25236395 Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. GO:0070010 GO:0070011 EC:3.4.-.- Reactome:R-HSA-205112 Reactome:R-HSA-3000243 Reactome:R-HSA-3000263 Reactome:R-HSA-3065958 Reactome:R-HSA-3065959 Reactome:R-HSA-3139027 Reactome:R-HSA-376149 Reactome:R-HSA-4167501 Reactome:R-HSA-448678 Reactome:R-HSA-5655483 Reactome:R-HSA-5684864 Reactome:R-HSA-5685902 Reactome:R-HSA-6803060 hydrolase, acting on peptide bonds peptide hydrolase activity protease activity peptidase activity, acting on D-amino acid peptides peptidase activity, acting on L-amino acid peptides proteinase activity molecular_function GO:0008233 peptidase activity GO:0008233 Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. GOC:jl ISBN:0815332181 Reactome:R-HSA-205112 gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 Reactome:R-HSA-3000243 Unknown lysosomal protease degrades CBLIF:RCbl to release Cbl Reactome:R-HSA-3000263 TCN2:RCbl is degraded to release RCbl Reactome:R-HSA-3065958 An unknown protease degrades ACACA Reactome:R-HSA-3065959 An unknown protease degrades hCBXs Reactome:R-HSA-3139027 Maturation of HIV Virion Reactome:R-HSA-376149 Proteolytic processing of SLIT Reactome:R-HSA-4167501 An unknown protease degrades ACACB Reactome:R-HSA-448678 CTSG cleaves CASP1(1-404) Reactome:R-HSA-5655483 USP1 autocleavage Reactome:R-HSA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB Reactome:R-HSA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC Reactome:R-HSA-6803060 DCD(63-110) is processed to DCD(63-109) The multiplication or reproduction of cells, resulting in the expansion of a cell population. biological_process cell proliferation GO:0008283 This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. cell population proliferation GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population. GOC:mah GOC:mb Any process that activates or increases the rate or extent of cell proliferation. up regulation of cell proliferation up-regulation of cell proliferation upregulation of cell proliferation activation of cell proliferation stimulation of cell proliferation biological_process positive regulation of cell proliferation GO:0008284 positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation. GOC:go_curators Any process that stops, prevents or reduces the rate or extent of cell proliferation. down regulation of cell proliferation down-regulation of cell proliferation downregulation of cell proliferation inhibition of cell proliferation biological_process negative regulation of cell proliferation GO:0008285 negative regulation of cell population proliferation GO:0008285 Any process that stops, prevents or reduces the rate or extent of cell proliferation. GOC:go_curators The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0009241 MetaCyc:POLYISOPRENSYN-PWY isoprenoid anabolism isoprenoid biosynthesis isoprenoid formation isoprenoid synthesis polyisoprenoid anabolism polyisoprenoid biosynthesis polyisoprenoid biosynthetic process polyisoprenoid formation polyisoprenoid synthesis polyterpene biosynthesis polyterpene biosynthetic process biological_process GO:0008299 isoprenoid biosynthetic process GO:0008299 The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. ISBN:0198506732 The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. lipid anabolism lipid biosynthesis lipid formation lipid synthesis lipogenesis biological_process GO:0008610 lipid biosynthetic process GO:0008610 The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GOC:go_curators lipogenesis GOC:sl Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. https://github.com/geneontology/go-ontology/issues/14208 GO:0008642 small protein activating enzyme activity molecular_function GO:0008641 ubiquitin-like modifier activating enzyme activity GO:0008641 Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GOC:jl GOC:mah The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. https://github.com/geneontology/go-ontology/issues/17904 https://github.com/geneontology/go-ontology/issues/27304 Wikipedia:Amino_acid_synthesis amino acid anabolism amino acid biosynthesis amino acid formation amino acid synthesis cellular amino acid biosynthetic process biological_process GO:0008652 amino acid biosynthetic process GO:0008652 The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. ISBN:0198506732 The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. jl 2012-10-17T15:52:35Z GO:0044243 GO:0044712 Wikipedia:Catabolism breakdown catabolism degradation multicellular organismal catabolic process biological_process single-organism catabolic process GO:0009056 catabolic process GO:0009056 The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. ISBN:0198547684 The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. jl 2012-10-17T15:52:18Z GO:0044274 GO:0044711 formation Wikipedia:Anabolism anabolism biosynthesis synthesis multicellular organismal biosynthetic process biological_process single-organism biosynthetic process GO:0009058 biosynthetic process GO:0009058 The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. GOC:curators ISBN:0198547684 The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. https://github.com/geneontology/go-ontology/issues/15249 https://github.com/geneontology/go-ontology/issues/25418 GO:0043284 biopolymer biosynthetic process macromolecule anabolism macromolecule biosynthesis macromolecule formation macromolecule synthesis biological_process GO:0009059 macromolecule biosynthetic process GO:0009059 The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:mah biopolymer biosynthetic process GOC:mtg_chebi_dec09 The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. aspartate family amino acid metabolism biological_process GO:0009066 aspartate family amino acid metabolic process GO:0009066 The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. GOC:ai The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. aspartate family amino acid anabolism aspartate family amino acid biosynthesis aspartate family amino acid formation aspartate family amino acid synthesis biological_process GO:0009067 aspartate family amino acid biosynthetic process GO:0009067 The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. GOC:ai The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid. MetaCyc:PWY-5097 lysine anabolism lysine biosynthesis lysine formation lysine synthesis biological_process GO:0009085 lysine biosynthetic process GO:0009085 The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid. GOC:go_curators The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. nucleobase metabolism biological_process GO:0009112 nucleobase metabolic process GO:0009112 The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. GOC:ma The controlled release of proteins from a cell. GO:0045166 GO:0045731 glycoprotein secretion protein secretion during cell fate commitment protein secretion resulting in cell fate commitment biological_process GO:0009306 protein secretion GO:0009306 The controlled release of proteins from a cell. GOC:ai The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. jl 2009-07-15T11:55:44Z GO:0044106 amine metabolism cellular amine metabolic process biological_process GO:0009308 amine metabolic process GO:0009308 The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. GOC:jl ISBN:0198506732 The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. amine anabolism amine biosynthesis amine formation amine synthesis biological_process GO:0009309 amine biosynthetic process GO:0009309 The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. GOC:jl ISBN:0198506732 The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. toxin anabolism toxin biosynthesis toxin formation toxin synthesis biological_process GO:0009403 toxin biosynthetic process GO:0009403 The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GOC:go_curators The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. toxin metabolism biological_process GO:0009404 toxin metabolic process GO:0009404 The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GOC:cab2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. response to environmental stimulus biological_process GO:0009605 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to external stimulus GO:0009605 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. GOC:hb Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. response to biotic stress biological_process GO:0009607 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to biotic stimulus GO:0009607 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. GOC:hb The rapid, localized death of plant cells in response to invasion by a pathogen. HR HR-PCD plant hypersensitive response biological_process GO:0009626 Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider the biological process term 'modulation by symbiont of host defense-related programmed cell death ; GO:0034053'. plant-type hypersensitive response GO:0009626 The rapid, localized death of plant cells in response to invasion by a pathogen. ISBN:0582227089 The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. embryogenesis and morphogenesis Wikipedia:Morphogenesis anatomical structure organization morphogenesis biological_process GO:0009653 anatomical structure morphogenesis GO:0009653 The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. GOC:go_curators ISBN:0521436125 The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. GO:0009795 embryogenesis and morphogenesis Wikipedia:Embryogenesis embryogenesis embryonal development biological_process GO:0009790 embryo development GO:0009790 The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. GOC:go_curators GOC:isa_complete GOC:mtg_sensu The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. biological_process GO:0009791 post-embryonic development GO:0009791 The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. GOC:go_curators The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. embryogenesis biological_process GO:0009792 embryo development ending in birth or egg hatching GO:0009792 The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. GOC:go_curators GOC:isa_complete GOC:mtg_sensu The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall). https://github.com/geneontology/go-ontology/issues/24413 GO:0075005 spore germination on or near host biological_process GO:0009847 spore germination GO:0009847 The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall). GOC:lr Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. regulation of anabolism regulation of biosynthesis regulation of formation regulation of synthesis biological_process GO:0009889 regulation of biosynthetic process GO:0009889 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. GOC:go_curators Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. down regulation of biosynthetic process down-regulation of biosynthetic process downregulation of biosynthetic process negative regulation of anabolism negative regulation of biosynthesis negative regulation of formation negative regulation of synthesis inhibition of biosynthetic process biological_process GO:0009890 negative regulation of biosynthetic process GO:0009890 Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. GOC:go_curators Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. positive regulation of anabolism positive regulation of biosynthesis positive regulation of formation positive regulation of synthesis up regulation of biosynthetic process up-regulation of biosynthetic process upregulation of biosynthetic process activation of biosynthetic process stimulation of biosynthetic process biological_process GO:0009891 positive regulation of biosynthetic process GO:0009891 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GO:0044252 down regulation of metabolic process down-regulation of metabolic process downregulation of metabolic process negative regulation of metabolism negative regulation of organismal metabolism inhibition of metabolic process inhibition of organismal metabolic process negative regulation of multicellular organismal metabolic process biological_process GO:0009892 negative regulation of metabolic process GO:0009892 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GOC:go_curators Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GO:0044253 positive regulation of metabolism up regulation of metabolic process up-regulation of metabolic process upregulation of metabolic process activation of metabolic process positive regulation of multicellular organismal metabolic process positive regulation of organismal metabolism stimulation of metabolic process stimulation of organismal metabolic process up-regulation of organismal metabolic process biological_process GO:0009893 positive regulation of metabolic process GO:0009893 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GOC:go_curators Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. jl 2012-12-11T16:56:55Z GO:0008151 GO:0044763 GO:0050875 cell physiology cellular physiological process cell growth and/or maintenance biological_process single-organism cellular process GO:0009987 This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. cellular process GO:0009987 Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GOC:go_curators GOC:isa_complete A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. endomembrane organization endomembrane system organisation biological_process GO:0010256 endomembrane system organization GO:0010256 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. GOC:mah GOC:sm endomembrane system organisation GOC:mah The infolding of a membrane. jl 2013-12-02T13:58:34Z GO:1902534 biological_process single-organism membrane invagination GO:0010324 membrane invagination GO:0010324 The infolding of a membrane. GOC:tb The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. https://github.com/geneontology/go-ontology/issues/22557 https://github.com/geneontology/go-ontology/issues/25419 Wikipedia:Gene_expression biological_process GO:0010467 gene expression GO:0010467 The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. GOC:txnOH-2018 PMID:25934543 PMID:31580950 Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). https://github.com/geneontology/go-ontology/issues/22557 Wikipedia:Regulation_of_gene_expression regulation of protein expression biological_process gene regulation regulation of gene product expression GO:0010468 This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. regulation of gene expression GO:0010468 Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). GOC:txnOH-2018 gene regulation GOC:cjm Any process that modulates the frequency, rate or extent of membrane disassembly. biological_process GO:0010549 regulation of membrane disassembly GO:0010549 Any process that modulates the frequency, rate or extent of membrane disassembly. GOC:dph GOC:tb Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0010556 regulation of macromolecule biosynthetic process GO:0010556 Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0010557 positive regulation of macromolecule biosynthetic process GO:0010557 Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0010558 negative regulation of macromolecule biosynthetic process GO:0010558 Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. biological_process GO:0010562 positive regulation of phosphorus metabolic process GO:0010562 Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. GOC:dph GOC:tb Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. biological_process GO:0010563 negative regulation of phosphorus metabolic process GO:0010563 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. GOC:dph GOC:tb Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. biological_process GO:0010564 regulation of cell cycle process GO:0010564 Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GOC:dph GOC:tb Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. biological_process GO:0010565 regulation of cellular ketone metabolic process GO:0010565 Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. biological_process GO:0010566 regulation of ketone biosynthetic process GO:0010566 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. GOC:dph GOC:tb Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0010604 positive regulation of macromolecule metabolic process GO:0010604 Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0010605 negative regulation of macromolecule metabolic process GO:0010605 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. posttranscriptional regulation of gene expression biological_process GO:0010608 post-transcriptional regulation of gene expression GO:0010608 Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. GOC:dph GOC:tb Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). https://github.com/geneontology/go-ontology/issues/22557 biological_process GO:0010628 positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). GOC:txnOH-2018 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). https://github.com/geneontology/go-ontology/issues/22557 biological_process gene silencing GO:0010629 This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). GOC:txnOH-2018 Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. positive regulation of organelle organisation biological_process positive regulation of organelle organization and biogenesis GO:0010638 positive regulation of organelle organization GO:0010638 Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. GOC:dph GOC:tb positive regulation of organelle organisation GOC:mah positive regulation of organelle organization and biogenesis GOC:mah Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. negative regulation of organelle organisation biological_process negative regulation of organelle organization and biogenesis GO:0010639 negative regulation of organelle organization GO:0010639 Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. GOC:dph GOC:tb negative regulation of organelle organisation GOC:mah negative regulation of organelle organization and biogenesis GOC:mah Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. biological_process GO:0010720 positive regulation of cell development GO:0010720 Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GOC:BHF GOC:dph GOC:tb Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. biological_process GO:0010721 negative regulation of cell development GO:0010721 Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GOC:BHF GOC:dph GOC:tb The cellular component assembly that is part of the initial shaping of the component during its developmental progression. biological_process GO:0010927 cellular component assembly involved in morphogenesis GO:0010927 The cellular component assembly that is part of the initial shaping of the component during its developmental progression. GOC:dph GOC:tb Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. tb 2009-04-27T09:53:22Z biological_process GO:0010948 negative regulation of cell cycle process GO:0010948 Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. tb 2009-05-20T11:42:50Z biological_process GO:0010966 regulation of phosphate transport GO:0010966 Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:dph GOC:tb A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. https://github.com/geneontology/go-ontology/issues/24835 GO:0016244 regulated cell death Wikipedia:Programmed_cell_death caspase-independent cell death non-apoptotic programmed cell death nonapoptotic programmed cell death biological_process PCD RCD caspase-independent apoptosis GO:0012501 Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death GO:0012501 A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. GOC:lr GOC:mtg_apoptosis A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. Wikipedia:Endomembrane_system cellular_component GO:0012505 endomembrane system GO:0012505 A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. GOC:lh The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015831 enzyme transport biological_process GO:0015031 protein transport GO:0015031 The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. biological_process GO:0015698 inorganic anion transport GO:0015698 The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. GOC:krc The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. biological_process GO:0015711 organic anion transport GO:0015711 The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. GOC:ai GOC:krc The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0015833 peptide transport GO:0015833 The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process amine/polyamine transport GO:0015837 amine transport GO:0015837 The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai ISBN:0198506732 The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0015849 organic acid transport GO:0015849 The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. ISBN:0198506732 The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. nucleobase transmembrane transport biological_process GO:0015851 nucleobase transport GO:0015851 The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. ISBN:0198506732 nucleobase transmembrane transport GOC:mah The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 nucleobase-containing compound transport GO:0015931 The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai nucleobase, nucleoside, nucleotide and nucleic acid transport GOC:dph GOC:tb A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. 2014-03-06T11:37:54Z GO:0016021 GO:0098589 GO:0098805 Wikipedia:Biological_membrane Wikipedia:Transmembrane_protein integral component of membrane integral to membrane membrane region region of membrane whole membrane cellular_component transmembrane GO:0016020 membrane GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GOC:dos GOC:mah ISBN:0815316194 transmembrane GOC:mah The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GO:0006724 GO:0044240 Wikipedia:Lipid_catabolism lipid breakdown lipid catabolism lipid degradation lipolysis multicellular organism lipid catabolic process multicellular organismal lipid catabolic process biological_process GO:0016042 lipid catabolic process GO:0016042 The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GOC:go_curators A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. GO:0044235 GO:0071842 cell organisation cellular component organisation at cellular level cellular component organisation in other organism cellular component organization at cellular level cellular component organization in other organism biological_process cell organization and biogenesis GO:0016043 cellular component organization GO:0016043 A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. GOC:ai GOC:jl GOC:mah cellular component organisation at cellular level GOC:mah cellular component organisation in other organism GOC:mah cell organization and biogenesis GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. vesicle organisation biological_process vesicle organization and biogenesis GO:0016050 vesicle organization GO:0016050 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. GOC:mah vesicle organization and biogenesis GOC:mah The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. organic acid anabolism organic acid biosynthesis organic acid formation organic acid synthesis biological_process GO:0016053 organic acid biosynthetic process GO:0016053 The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. ISBN:0198506732 The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. RNA metabolism biological_process GO:0016070 RNA metabolic process GO:0016070 The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. ISBN:0198506732 The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. sesquiterpenoid anabolism sesquiterpenoid biosynthesis sesquiterpenoid formation sesquiterpenoid synthesis biological_process GO:0016106 sesquiterpenoid biosynthetic process GO:0016106 The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. GOC:go_curators The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. Wikipedia:Terpenoid terpenoid anabolism terpenoid biosynthesis terpenoid formation terpenoid synthesis biological_process GO:0016114 terpenoid biosynthetic process GO:0016114 The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. GOC:ai A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. https://github.com/geneontology/go-ontology/issues/25421 GO:0006899 vesicle transport vesicular transport nonselective vesicle transport biological_process protein sorting along secretory pathway vesicle trafficking GO:0016192 vesicle-mediated transport GO:0016192 A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. GOC:ai GOC:mah ISBN:08789310662000 vesicular transport GOC:mah The autophagic process that proceeds via the formation of an autophagosome. https://github.com/geneontology/go-ontology/issues/26115 GO:0034262 autophagy selective autophagy biological_process GO:0016236 macroautophagy GO:0016236 The autophagic process that proceeds via the formation of an autophagosome. PMID:24366339 true Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Reactome:R-HSA-6788855 Reactome:R-HSA-6788867 phosphokinase activity molecular_function GO:0016301 Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. kinase activity GO:0016301 Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. ISBN:0198506732 Reactome:R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm Reactome:R-HSA-6788867 FN3K phosphorylates ketosamines The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. https://github.com/geneontology/go-ontology/issues/26424 Wikipedia:Phosphorylation biological_process GO:0016310 phosphorylation GO:0016310 The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. ISBN:0198506732 Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. Reactome:R-HSA-6810472 molecular_function GO:0016462 pyrophosphatase activity GO:0016462 Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. GOC:curators https://en.wikipedia.org/wiki/Pyrophosphatase Reactome:R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. EC:2.-.-.- Reactome:R-HSA-1483089 Reactome:R-HSA-1483186 Reactome:R-HSA-5668414 Reactome:R-HSA-8868783 molecular_function GO:0016740 transferase activity GO:0016740 Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. ISBN:0198506732 Reactome:R-HSA-1483089 PE is converted to PS by PTDSS2 Reactome:R-HSA-1483186 PC is converted to PS by PTDSS1 Reactome:R-HSA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK Reactome:R-HSA-8868783 TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). https://github.com/geneontology/go-ontology/issues/20486 GO:0008415 EC:2.3.-.- Reactome:R-HSA-159431 Reactome:R-HSA-192312 Reactome:R-HSA-193491 Reactome:R-HSA-6792572 Reactome:R-HSA-8858298 transferase activity, transferring acyl groups molecular_function GO:0016746 acyltransferase activity GO:0016746 Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). EC:2.3.-.- Reactome:R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine Reactome:R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate Reactome:R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate Reactome:R-HSA-6792572 LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs Reactome:R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). EC:2.3.2.- transferase activity, transferring amino-acyl groups molecular_function GO:0016755 aminoacyltransferase activity GO:0016755 Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). GOC:jl Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). EC:2.7.-.- molecular_function GO:0016772 Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. transferase activity, transferring phosphorus-containing groups GO:0016772 Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GOC:jl ISBN:0198506732 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. EC:3.-.-.- Reactome:R-HSA-1236938 Reactome:R-HSA-2029475 Reactome:R-HSA-5694583 Reactome:R-HSA-5695964 Reactome:R-HSA-6786190 Reactome:R-HSA-6788295 Reactome:R-HSA-8938314 Reactome:R-HSA-8952137 molecular_function GO:0016787 hydrolase activity GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. ISBN:0198506732 Reactome:R-HSA-1236938 Partial proteolysis of antigen in phagolysosomes Reactome:R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation Reactome:R-HSA-5694583 ABHD4 hydrolyses NAPE Reactome:R-HSA-5695964 ABHD14B hydrolyses PNPB Reactome:R-HSA-6786190 CMBL hydrolyses OM to OLMS Reactome:R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP Reactome:R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP Reactome:R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate Catalysis of the hydrolysis of any glycosyl bond. EC:3.2.-.- Reactome:R-HSA-1793176 Reactome:R-HSA-2065233 glycosidase activity N-glycosylase glycosylase molecular_function GO:0016798 hydrolase activity, acting on glycosyl bonds GO:0016798 Catalysis of the hydrolysis of any glycosyl bond. GOC:jl Reactome:R-HSA-1793176 DS is cleaved from its proteoglycan Reactome:R-HSA-2065233 CS is cleaved from its proteoglycan Catalysis of the hydrolysis of any acid anhydride. EC:3.6.-.- hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement molecular_function GO:0016817 hydrolase activity, acting on acid anhydrides GO:0016817 Catalysis of the hydrolysis of any acid anhydride. GOC:jl Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. EC:3.6.1.- Reactome:R-HSA-9731590 Reactome:R-HSA-9731613 Reactome:R-HSA-9731632 molecular_function GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides GO:0016818 Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. GOC:jl Reactome:R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP Reactome:R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP Reactome:R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. https://github.com/geneontology/go-ontology/issues/19380 EC:6.-.-.- synthetase activity molecular_function GO:0016874 ligase activity GO:0016874 Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. GOC:mah synthetase activity GOC:jh2 Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.2.-.- ligase activity, forming carbon-sulphur bonds molecular_function GO:0016877 ligase activity, forming carbon-sulfur bonds GO:0016877 Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.2.-.- Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. https://github.com/geneontology/go-ontology/issues/19078 https://github.com/geneontology/go-ontology/issues/20498 https://github.com/geneontology/go-ontology/issues/21612 https://github.com/geneontology/go-ontology/issues/22371 GO:0004002 GO:0042623 RHEA:13065 Reactome:R-HSA-159101 Reactome:R-HSA-3371422 Reactome:R-HSA-416985 Reactome:R-HSA-5618093 Reactome:R-HSA-5654989 Reactome:R-HSA-5694425 Reactome:R-HSA-6809015 Reactome:R-HSA-6811422 Reactome:R-HSA-6814670 Reactome:R-HSA-6814678 Reactome:R-HSA-6814683 Reactome:R-HSA-8847638 Reactome:R-HSA-8868658 Reactome:R-HSA-8939203 Reactome:R-HSA-9038161 Reactome:R-HSA-917693 Reactome:R-HSA-9609860 Reactome:R-HSA-9668415 Reactome:R-HSA-9706399 Reactome:R-HSA-9749350 ATP hydrolase activity ATP phosphohydrolase activity adenosine 5'-triphosphatase activity adenosine triphosphatase activity adenosinetriphosphatase activity molecular_function ATP monophosphatase activity GO:0016887 Note that this term is meant to specifically represent the ATPase activity of proteins using ATP as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function. ATP hydrolysis activity GO:0016887 Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. RHEA:13065 Reactome:R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) Reactome:R-HSA-3371422 ATP hydrolysis by HSP70 Reactome:R-HSA-416985 Trafficking of GluR2-containing AMPA receptors to synapse Reactome:R-HSA-5618093 ATP hydrolysis by HSP90 Reactome:R-HSA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA Reactome:R-HSA-5694425 NSF ATPase activity dissociates cis-SNARE Reactome:R-HSA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi Reactome:R-HSA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER Reactome:R-HSA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation Reactome:R-HSA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN Reactome:R-HSA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN Reactome:R-HSA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane Reactome:R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating Reactome:R-HSA-8939203 HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex Reactome:R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG Reactome:R-HSA-917693 ESCRT Disassembly Reactome:R-HSA-9609860 Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP Reactome:R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope Reactome:R-HSA-9706399 RHOBTB3 hydrolyzes ATP Reactome:R-HSA-9749350 ATP-dependent release of CDT1 from the OCCM complex Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. https://github.com/geneontology/go-ontology/issues/21232 https://github.com/geneontology/go-ontology/issues/23401 apyrase activity nucleoside 5-triphosphatase activity nucleoside triphosphatase activity nucleoside triphosphate hydrolase activity nucleoside triphosphate phosphatase activity nucleoside-triphosphatase activity EC:3.6.1.15 MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN RHEA:23680 Reactome:R-HSA-8850846 Reactome:R-HSA-8851089 Reactome:R-HSA-8851110 Reactome:R-HSA-8851234 Reactome:R-HSA-8851494 Reactome:R-HSA-8851538 NTPase activity molecular_function nucleoside triphosphate phosphohydrolase activity nucleoside-5-triphosphate phosphohydrolase activity GO:0017111 ribonucleoside triphosphate phosphatase activity GO:0017111 Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. RHEA:23680 nucleoside 5-triphosphatase activity EC:3.6.1.15 Reactome:R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates Reactome:R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates Reactome:R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates Reactome:R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates Reactome:R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates Reactome:R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0016478 down regulation of protein biosynthetic process down-regulation of protein biosynthetic process downregulation of protein biosynthetic process negative regulation of protein anabolism negative regulation of protein biosynthesis negative regulation of protein biosynthetic process negative regulation of protein formation negative regulation of protein synthesis inhibition of protein biosynthetic process biological_process protein biosynthesis inhibitor activity protein biosynthetic process inhibitor activity GO:0017148 negative regulation of translation GO:0017148 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GOC:isa_complete The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). heterocycle anabolism heterocycle biosynthesis heterocycle formation heterocycle synthesis biological_process GO:0018130 heterocycle biosynthetic process GO:0018130 The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). ISBN:0198547684 The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds. ether metabolism organic ether metabolic process organic ether metabolism biological_process GO:0018904 ether metabolic process GO:0018904 The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds. GOC:pr ISBN:0198506732 Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. Wikipedia:Host_(biology) host organism cellular_component GO:0018995 host cellular component GO:0018995 Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. ISBN:0198506732 Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism biological_process regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0019219 regulation of nucleobase-containing compound metabolic process GO:0019219 Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GOC:go_curators regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. regulation of phosphate metabolism biological_process GO:0019220 regulation of phosphate metabolic process GO:0019220 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. GOC:go_curators Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GO:0044246 regulation of metabolism regulation of multicellular organismal metabolic process regulation of organismal metabolic process biological_process GO:0019222 regulation of metabolic process GO:0019222 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GOC:go_curators regulation of organismal metabolic process GOC:tb The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. aromatic compound anabolism aromatic compound biosynthesis aromatic compound formation aromatic compound synthesis aromatic hydrocarbon biosynthesis aromatic hydrocarbon biosynthetic process biological_process GO:0019438 aromatic compound biosynthetic process GO:0019438 The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. GOC:ai The chemical reactions and pathways involving a protein. Includes protein modification. https://github.com/geneontology/go-ontology/issues/23112 https://github.com/geneontology/go-ontology/issues/27189 GO:0006411 GO:0044267 GO:0044268 Wikipedia:Protein_metabolism cellular protein metabolic process cellular protein metabolism protein metabolic process and modification protein metabolism protein metabolism and modification multicellular organismal protein metabolic process biological_process GO:0019538 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. protein metabolic process GO:0019538 The chemical reactions and pathways involving a protein. Includes protein modification. GOC:ma The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. Wikipedia:Secondary_metabolism secondary metabolism secondary metabolite metabolic process secondary metabolite metabolism biological_process GO:0019748 secondary metabolic process GO:0019748 The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. GOC:go_curators The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. polyhydric alcohol metabolic process polyol metabolism biological_process GO:0019751 polyol metabolic process GO:0019751 The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. PMID:30240188 The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). carboxylic acid metabolism biological_process GO:0019752 carboxylic acid metabolic process GO:0019752 The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). ISBN:0198506732 The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. one carbon compound transport biological_process GO:0019755 one-carbon compound transport GO:0019755 The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. Reactome:R-HSA-5681999 APG12 conjugating enzyme activity APG12 ligase activity Atg12 conjugating enzyme activity Atg12 ligase activity molecular_function GO:0019777 Atg12 transferase activity GO:0019777 Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. GOC:mah PMID:12826404 Reactome:R-HSA-5681999 ATG10 transfers ATG12 from ATG7 to ATG10 Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. molecular_function APG12 activating enzyme activity GO:0019778 Atg12 activating enzyme activity GO:0019778 Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. GOC:mah APG12 activating enzyme activity GOC:vw Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue. https://github.com/geneontology/go-ontology/issues/25472 Atg8-specific protease activity APG8-specific protease activity ATG8-PE deconjugation activity ATG8-PE hydrolase activity Atg8-specific peptidase activity molecular_function APG8-PE hydrolase GO:0019786 protein-phosphatidylethanolamide deconjugating activity GO:0019786 Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue. PMID:22240591 PMID:22652539 PMID:28330855 PMID:2882172 PMID:28901328 APG8-specific protease activity GOC:vw Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. https://github.com/geneontology/go-ontology/issues/24697 GO:0008639 GO:0008640 E2 Reactome:R-HSA-5678490 Reactome:R-HSA-688137 small conjugating protein transferase activity small conjugating protein ligase activity small protein conjugating enzyme activity ubiquitin-like conjugating enzyme activity ubiquitin-like-protein ligase activity molecular_function E3 GO:0019787 ubiquitin-like protein transferase activity GO:0019787 Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. GOC:mah GOC:rn PMID:10806345 PMID:10884686 Reactome:R-HSA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE Reactome:R-HSA-688137 RIP2 is K63 polyubiquitinated small conjugating protein transferase activity GOC:dph small conjugating protein ligase activity GOC:dph E3 GOC:dph The rupture of cell membranes and the loss of cytoplasm. lysis Wikipedia:Cytolysis biological_process autolysin activity bacteriocin activity bacteriolytic toxin activity holin lysin activity necrosis GO:0019835 cytolysis GO:0019835 The rupture of cell membranes and the loss of cytoplasm. UniProtKB-KW:KW-0204 A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). https://github.com/geneontology/go-ontology/issues/22929 Wikipedia:Sexual_reproduction biological_process GO:0019953 Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. sexual reproduction GO:0019953 A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). Wikipedia:Sexual_reproduction A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells. https://github.com/geneontology/go-ontology/issues/22929 Wikipedia:Asexual_reproduction biological_process parthenogenesis GO:0019954 asexual reproduction GO:0019954 A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells. ISBN:0387520546 PMID:22977071 PMID:28779329 PMID:29559496 parthenogenesis Wikipedia:Parthenogenesis The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. biological_process GO:0022402 cell cycle process GO:0022402 The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. GOC:isa_complete GOC:mtg_cell_cycle One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. biological_process GO:0022403 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). cell cycle phase GO:0022403 One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. GOC:mtg_cell_cycle A cellular process that results in the breakdown of a cellular component. GO:0071845 cell structure disassembly cellular component disassembly at cellular level biological_process GO:0022411 cellular component disassembly GO:0022411 A cellular process that results in the breakdown of a cellular component. GOC:isa_complete A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. https://github.com/geneontology/go-ontology/issues/27054 jl 2012-09-19T15:56:06Z GO:0044702 Wikipedia:Reproduction biological_process single organism reproductive process GO:0022414 reproductive process GO:0022414 A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. GOC:dph GOC:isa_complete The aggregation, arrangement and bonding together of a cellular component. GO:0071844 cell structure assembly cellular component assembly at cellular level biological_process GO:0022607 cellular component assembly GO:0022607 The aggregation, arrangement and bonding together of a cellular component. GOC:isa_complete A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. RNA-protein complex biogenesis ribonucleoprotein complex biogenesis and assembly biological_process GO:0022613 ribonucleoprotein complex biogenesis GO:0022613 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. GOC:isa_complete GOC:mah RNA-protein complex biogenesis GOC:mah ribonucleoprotein complex biogenesis and assembly GOC:mah The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. RNA-protein complex assembly RNP complex assembly ribonucleoprotein complex assembly biological_process GO:0022618 protein-RNA complex assembly GO:0022618 The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. GOC:jl The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. https://github.com/geneontology/go-ontology/issues/24390 Wikipedia:Cellular_differentiation biological_process GO:0030154 cell differentiation GO:0030154 The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. ISBN:0198506732 Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GO:0005529 sugar binding molecular_function selectin GO:0030246 carbohydrate binding GO:0030246 Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GOC:mah Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0002506 polysaccharide assembly with MHC class II protein complex molecular_function GO:0030247 polysaccharide binding GO:0030247 Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GOC:mah The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. membrane breakdown membrane catabolism membrane degradation biological_process GO:0030397 membrane disassembly GO:0030397 The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. GOC:mah A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. septum cross wall cellular_component GO:0030428 cell septum GO:0030428 A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GOC:clt ISBN:0471940526 The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. https://github.com/geneontology/go-ontology/issues/24410 Wikipedia:Sporogenesis cellular spore formation by sporulation spore biosynthesis spore differentiation spore formation biological_process GO:0030435 Note that the synonym 'spore differentiation', like the term name and definition, refers to differentiation into a spore rather than any subsequent developmental changes that a spore may undergo. sporulation resulting in formation of a cellular spore GO:0030435 The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. GOC:mah GOC:pamgo_curators ISBN:0072992913 cellular spore formation by sporulation GOC:dph GOC:tb The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi. asexual reproductive sporulation asexual spore formation mitotic spore formation mitotic sporulation biological_process GO:0030436 asexual sporulation GO:0030436 The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi. GOC:mah PMID:9529886 The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. biological_process GO:0030447 filamentous growth GO:0030447 The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. GOC:mcc PMID:11729141 Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls. https://github.com/geneontology/go-ontology/issues/19013 GO:0075061 formation of symbiont invasive hypha in host formation of symbiont invasive hypha within host formation of symbiont invasive hypha within host during symbiotic interaction invasive hyphal growth symbiont invasive hypha formation within host biological_process GO:0030448 hyphal growth GO:0030448 Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls. GOC:mcc ISBN:0471522295 A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. NIF_Subcellular:sao830981606 cellular_component intracellular membrane GO:0031090 organelle membrane GO:0031090 A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. GOC:dos GOC:mah intracellular membrane NIF_Subcellular:sao830981606 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. regulation of cellular metabolism biological_process GO:0031323 regulation of cellular metabolic process GO:0031323 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. down regulation of cellular metabolic process down-regulation of cellular metabolic process downregulation of cellular metabolic process negative regulation of cellular metabolism inhibition of cellular metabolic process biological_process GO:0031324 negative regulation of cellular metabolic process GO:0031324 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GOC:mah Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. positive regulation of cellular metabolism up regulation of cellular metabolic process up-regulation of cellular metabolic process upregulation of cellular metabolic process activation of cellular metabolic process stimulation of cellular metabolic process biological_process GO:0031325 positive regulation of cellular metabolic process GO:0031325 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GOC:mah Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. regulation of cellular anabolism regulation of cellular biosynthesis regulation of cellular formation regulation of cellular synthesis biological_process GO:0031326 regulation of cellular biosynthetic process GO:0031326 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. down regulation of cellular biosynthetic process down-regulation of cellular biosynthetic process downregulation of cellular biosynthetic process negative regulation of cellular anabolism negative regulation of cellular biosynthesis negative regulation of cellular formation negative regulation of cellular synthesis inhibition of cellular biosynthetic process biological_process GO:0031327 negative regulation of cellular biosynthetic process GO:0031327 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GOC:mah Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. positive regulation of cellular anabolism positive regulation of cellular biosynthesis positive regulation of cellular formation positive regulation of cellular synthesis up regulation of cellular biosynthetic process up-regulation of cellular biosynthetic process upregulation of cellular biosynthetic process activation of cellular biosynthetic process stimulation of cellular biosynthetic process biological_process GO:0031328 positive regulation of cellular biosynthetic process GO:0031328 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. down regulation of protein complex assembly down-regulation of protein complex assembly downregulation of protein complex assembly inhibition of protein complex assembly biological_process negative regulation of protein complex assembly GO:0031333 negative regulation of protein-containing complex assembly GO:0031333 Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. GOC:mah Any process that activates or increases the frequency, rate or extent of protein complex assembly. up regulation of protein complex assembly up-regulation of protein complex assembly upregulation of protein complex assembly activation of protein complex assembly stimulation of protein complex assembly biological_process positive regulation of protein complex assembly GO:0031334 positive regulation of protein-containing complex assembly GO:0031334 Any process that activates or increases the frequency, rate or extent of protein complex assembly. GOC:mah A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. https://github.com/geneontology/go-ontology/issues/22021 GO:0034629 establishment and maintenance of protein complex localization protein complex localisation biological_process cellular protein complex localisation cellular protein complex localization cellular protein-containing complex localization establishment and maintenance of cellular protein complex localization protein complex localization GO:0031503 protein-containing complex localization GO:0031503 A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. GOC:mah protein complex localisation GOC:mah cellular protein complex localisation GOC:mah Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. NIF_Subcellular:sao1687101204 cellular_component GO:0031965 nuclear membrane GO:0031965 Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. GOC:mah GOC:pz A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. cellular_component GO:0031967 organelle envelope GO:0031967 A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. GOC:mah GOC:pz A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. cellular_component GO:0031975 envelope GO:0031975 A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. GOC:mah GOC:pz The slender tubular outgrowth first produced by most spores in germination. Wikipedia:Germ_tube cellular_component GO:0032179 germ tube GO:0032179 The slender tubular outgrowth first produced by most spores in germination. ISBN:0877799148 Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 regulation of nucleobase-containing compound transport GO:0032239 Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GOC:dph GOC:tb Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport biological_process negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032240 negative regulation of nucleobase-containing compound transport GO:0032240 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GOC:dph GOC:tb Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport activation of nucleobase, nucleoside, nucleotide and nucleic acid transport stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport biological_process positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032241 positive regulation of nucleobase-containing compound transport GO:0032241 Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. biological_process GO:0032386 regulation of intracellular transport GO:0032386 Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. down regulation of intracellular transport down-regulation of intracellular transport downregulation of intracellular transport inhibition of intracellular transport biological_process GO:0032387 negative regulation of intracellular transport GO:0032387 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. GOC:mah Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. up regulation of intracellular transport up-regulation of intracellular transport upregulation of intracellular transport activation of intracellular transport stimulation of intracellular transport biological_process GO:0032388 positive regulation of intracellular transport GO:0032388 Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. GOC:mah Any biological process, occurring at the level of a multicellular organism, pertinent to its function. jl 2012-09-19T16:07:47Z GO:0044707 GO:0050874 organismal physiological process biological_process single-multicellular organism process GO:0032501 multicellular organismal process GO:0032501 Any biological process, occurring at the level of a multicellular organism, pertinent to its function. GOC:curators GOC:dph GOC:isa_complete GOC:tb A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. jl 2012-12-19T12:21:31Z GO:0044767 development biological_process single-organism developmental process GO:0032502 developmental process GO:0032502 A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. GOC:isa_complete The directed movement of a protein from one location to another within a lipid bilayer. protein translocation within membrane receptor translocation within membrane receptor transport within lipid bilayer biological_process GO:0032594 protein transport within lipid bilayer GO:0032594 The directed movement of a protein from one location to another within a lipid bilayer. GOC:mah The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. GO:0062103 RNA anabolism RNA biosynthesis RNA formation RNA synthesis double-stranded RNA biosynthesis double-stranded RNA biosynthetic process dsRNA biosynthesis dsRNA biosynthetic process biological_process GO:0032774 Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. RNA biosynthetic process GO:0032774 The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. GOC:mah GOC:txnOH dsRNA biosynthetic process GOC:BHF GOC:BHF_telomere GOC:nc GOC:rl Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. regulation of localisation biological_process GO:0032879 regulation of localization GO:0032879 Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. GOC:mah regulation of localisation GOC:mah Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. https://github.com/geneontology/go-ontology/issues/22021 jl 2015-01-20T14:32:14Z GO:1903827 regulation of cellular protein localisation regulation of cellular protein localization regulation of protein localisation biological_process GO:0032880 regulation of protein localization GO:0032880 Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. GOC:dph GOC:mah GOC:tb regulation of cellular protein localisation GOC:TermGenie regulation of protein localisation GOC:mah Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0032890 regulation of organic acid transport GO:0032890 Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of organic acid transport down-regulation of organic acid transport downregulation of organic acid transport inhibition of organic acid transport biological_process GO:0032891 negative regulation of organic acid transport GO:0032891 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. up regulation of organic acid transport up-regulation of organic acid transport upregulation of organic acid transport activation of organic acid transport stimulation of organic acid transport biological_process GO:0032892 positive regulation of organic acid transport GO:0032892 Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah The controlled release of a substance by a cell. Wikipedia:Secretion cellular secretion biological_process GO:0032940 secretion by cell GO:0032940 The controlled release of a substance by a cell. GOC:mah The disaggregation of a protein-containing macromolecular complex into its constituent components. https://github.com/geneontology/go-ontology/issues/22580 GO:0034623 GO:0043241 GO:0043624 protein complex disassembly biological_process cellular macromolecule complex disassembly cellular protein complex disassembly macromolecule complex disassembly GO:0032984 protein-containing complex disassembly GO:0032984 The disaggregation of a protein-containing macromolecular complex into its constituent components. GOC:mah The disaggregation of a protein-RNA complex into its constituent components. https://github.com/geneontology/go-ontology/issues/25143 RNA-protein complex disassembly RNP complex disassembly ribonucleoprotein complex disassembly biological_process GO:0032988 protein-RNA complex disassembly GO:0032988 The disaggregation of a protein-RNA complex into its constituent components. GOC:mah The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. https://github.com/geneontology/go-ontology/issues/25496 https://github.com/geneontology/go-ontology/issues/26249 cellular component morphogenesis cellular structure morphogenesis biological_process GO:0032989 cellular anatomical entity morphogenesis GO:0032989 The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. GOC:dph GOC:mah GOC:tb cellular structure morphogenesis GOC:dph GOC:tb A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. GO:0043234 macromolecular complex macromolecule complex protein containing complex protein complex protein-protein complex cellular_component GO:0032991 A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. GOC:dos GOC:mah Any process in which a macromolecule is transported to, or maintained in, a specific location. macromolecule localisation biological_process GO:0033036 macromolecule localization GO:0033036 Any process in which a macromolecule is transported to, or maintained in, a specific location. GOC:mah macromolecule localisation GOC:mah Any process in which a polysaccharide is transported to, or maintained in, a specific location. polysaccharide localisation biological_process GO:0033037 polysaccharide localization GO:0033037 Any process in which a polysaccharide is transported to, or maintained in, a specific location. GOC:mah polysaccharide localisation GOC:mah Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. regulation of organelle organisation biological_process regulation of organelle organization and biogenesis GO:0033043 regulation of organelle organization GO:0033043 Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. GOC:mah regulation of organelle organisation GOC:mah regulation of organelle organization and biogenesis GOC:mah The deposition or aggregation of coloring matter in a cell. biological_process GO:0033059 cellular pigmentation GO:0033059 The deposition or aggregation of coloring matter in a cell. GOC:mtg_MIT_16mar07 Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. biological_process GO:0033157 regulation of intracellular protein transport GO:0033157 Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. GOC:mah Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. regulation of amine metabolism regulation of cellular amine metabolic process biological_process GO:0033238 regulation of amine metabolic process GO:0033238 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. negative regulation of amine metabolism negative regulation of cellular amine metabolic process biological_process GO:0033239 negative regulation of amine metabolic process GO:0033239 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. GOC:mah Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. positive regulation of amine metabolism positive regulation of cellular amine metabolic process biological_process GO:0033240 positive regulation of amine metabolic process GO:0033240 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. GOC:mah A process in which a protein is transported to, or maintained in, a location within an organelle. protein localisation to organelle protein localization in organelle biological_process GO:0033365 protein localization to organelle GO:0033365 A process in which a protein is transported to, or maintained in, a location within an organelle. GOC:mah protein localisation to organelle GOC:mah protein localization in organelle GOC:mah Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). biological_process GO:0033554 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. cellular response to stress GO:0033554 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. down regulation of kinase activity down-regulation of kinase activity downregulation of kinase activity inhibition of kinase activity kinase inhibitor biological_process GO:0033673 negative regulation of kinase activity GO:0033673 Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GOC:mah Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. up regulation of kinase activity up-regulation of kinase activity upregulation of kinase activity kinase activator stimulation of kinase activity biological_process GO:0033674 positive regulation of kinase activity GO:0033674 Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GOC:mah Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules. https://github.com/geneontology/go-ontology/issues/20255 host programmed cell death induced by symbiont programmed cell death induced by symbiont biological_process GO:0034050 Note that this term is to be used to annotate gene products in the host, not the symbiont. To annotate gene products in the symbiont that induce programmed cell death in the host, consider the biological process term 'symbiont-mediated activation of host programmed cell death' ; GO:0052042'. symbiont-induced defense-related programmed cell death GO:0034050 Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules. GOC:pamgo_curators Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. regulation of amide metabolism regulation of cellular amide metabolic process biological_process GO:0034248 regulation of amide metabolic process GO:0034248 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. negative regulation of amide metabolism negative regulation of cellular amide metabolic process biological_process GO:0034249 negative regulation of amide metabolic process GO:0034249 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. GOC:mah Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. positive regulation of amide metabolism positive regulation of cellular amide metabolic process biological_process GO:0034250 positive regulation of amide metabolic process GO:0034250 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. GOC:mah The formation of spores derived from the products of meiosis. meiotic spore formation meiotic sporulation sexual spore formation biological_process GO:0034293 sexual sporulation GO:0034293 The formation of spores derived from the products of meiosis. GOC:mah The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. biological_process GO:0034301 endospore formation GO:0034301 The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. GOC:ds GOC:mah ISBN:0470090278 The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. monohydric alcohol metabolic process primary alcohol metabolism biological_process GO:0034308 primary alcohol metabolic process GO:0034308 The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. GOC:mah primary alcohol metabolism GOC:mah The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. monohydric alcohol biosynthetic process primary alcohol anabolism primary alcohol biosynthesis primary alcohol formation primary alcohol synthesis biological_process GO:0034309 primary alcohol biosynthetic process GO:0034309 The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. GOC:mah primary alcohol anabolism GOC:mah primary alcohol biosynthesis GOC:mah primary alcohol formation GOC:mah primary alcohol synthesis GOC:mah A process in which a protein transports or maintains the localization of another protein to the nucleus. 2012-11-07T15:45:54Z GO:0044744 protein localisation to nucleus protein localization in cell nucleus protein localization in nucleus biological_process protein targeting to nucleus GO:0034504 protein localization to nucleus GO:0034504 A process in which a protein transports or maintains the localization of another protein to the nucleus. GOC:ecd protein localisation to nucleus GOC:mah protein localization in nucleus GOC:mah GO:0034613 true GO:0034629 true The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. https://github.com/geneontology/go-ontology/issues/26424 cellular nitrogen compound metabolism biological_process GO:0034641 cellular nitrogen compound metabolic process GO:0034641 The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. GOC:mah The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. nucleobase, nucleoside, nucleotide and nucleic acid anabolism nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis nucleobase, nucleoside, nucleotide and nucleic acid formation nucleobase, nucleoside, nucleotide and nucleic acid synthesis biological_process GO:0034654 nucleobase-containing compound biosynthetic process GO:0034654 The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. GOC:mah The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. biological_process GO:0035190 syncytial nuclear migration GO:0035190 The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. GOC:bf ISBN:0879694238 PMID:8314839 The directed movement of a protein to a specific location within the extracellular region. bf 2010-11-09T10:25:08Z establishment of protein localisation in extracellular region establishment of protein localization in extracellular region biological_process GO:0035592 establishment of protein localization to extracellular region GO:0035592 The directed movement of a protein to a specific location within the extracellular region. GOC:BHF GOC:bf establishment of protein localisation in extracellular region GOC:mah Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. bf 2012-01-17T04:20:34Z molecular_function GO:0036094 Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. small molecule binding GO:0036094 Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. GOC:curators GOC:pde GOC:pm The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). https://github.com/geneontology/go-ontology/issues/23112 bf 2012-04-26T01:47:12Z GO:0006464 cellular protein modification process process resulting in protein modification protein modification biological_process GO:0036211 protein modification process GO:0036211 The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). GOC:bf GOC:jl protein modification GOC:bf The increase in size or mass of an entire organism, a part of an organism or a cell. GO:0048590 biological_process growth pattern non-developmental growth GO:0040007 See also the biological process term 'cell growth ; GO:0016049'. growth GO:0040007 The increase in size or mass of an entire organism, a part of an organism or a cell. GOC:bf GOC:ma non-developmental growth GOC:mah Any process that activates or increases the frequency, rate or extent of embryonic development. up regulation of embryonic development up-regulation of embryonic development upregulation of embryonic development activation of embryonic development stimulation of embryonic development biological_process GO:0040019 positive regulation of embryonic development GO:0040019 Any process that activates or increases the frequency, rate or extent of embryonic development. GOC:go_curators Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. regulation of meiosis biological_process GO:0040020 regulation of meiotic nuclear division GO:0040020 Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. GOC:ems GOC:ma regulation of meiosis GOC:vw Any process that modulates the frequency, rate or extent of cell proliferation. biological_process regulation of cell proliferation GO:0042127 regulation of cell population proliferation GO:0042127 Any process that modulates the frequency, rate or extent of cell proliferation. GOC:jl The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. ketone metabolism biological_process GO:0042180 cellular ketone metabolic process GO:0042180 The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GOC:jl ISBN:0787650153 The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. ketone anabolism ketone biosynthesis ketone formation ketone synthesis biological_process GO:0042181 ketone biosynthetic process GO:0042181 The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GOC:go_curators Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. biological_process GO:0042325 regulation of phosphorylation GO:0042325 Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. GOC:jl Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. down regulation of phosphorylation down-regulation of phosphorylation downregulation of phosphorylation inhibition of phosphorylation biological_process GO:0042326 negative regulation of phosphorylation GO:0042326 Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. GOC:jl Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. up regulation of phosphorylation up-regulation of phosphorylation upregulation of phosphorylation activation of phosphorylation stimulation of phosphorylation biological_process GO:0042327 positive regulation of phosphorylation GO:0042327 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. GOC:jl The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0042886 amide transport GO:0042886 The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:jl ISBN:0198506732 The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. peptide anabolism peptide biosynthesis peptide formation peptide synthesis biological_process GO:0043043 peptide biosynthetic process GO:0043043 The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. GOC:dph GOC:jl A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. extracellular structure organisation extracellular structure organization and biogenesis biological_process GO:0043062 extracellular structure organization GO:0043062 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. GOC:ai GOC:dph GOC:jl GOC:mah extracellular structure organization and biogenesis GOC:dph GOC:jl GOC:mah Any process that activates or increases the activity of an enzyme. GO:0048554 positive regulation of enzyme activity up regulation of enzyme activity up-regulation of enzyme activity upregulation of enzyme activity activation of enzyme activity activation of metalloenzyme activity positive regulation of metalloenzyme activity stimulation of enzyme activity stimulation of metalloenzyme activity up regulation of metalloenzyme activity up-regulation of metalloenzyme activity upregulation of metalloenzyme activity biological_process GO:0043085 positive regulation of catalytic activity GO:0043085 Any process that activates or increases the activity of an enzyme. GOC:ebc GOC:jl GOC:tb GOC:vw positive regulation of enzyme activity GOC:tb Any process that stops or reduces the activity of an enzyme. GO:0048553 down regulation of enzyme activity down-regulation of enzyme activity down-regulation of metalloenzyme activity downregulation of enzyme activity negative regulation of enzyme activity down regulation of metalloenzyme activity downregulation of metalloenzyme activity inhibition of enzyme activity inhibition of metalloenzyme activity negative regulation of metalloenzyme activity biological_process GO:0043086 negative regulation of catalytic activity GO:0043086 Any process that stops or reduces the activity of an enzyme. GOC:ebc GOC:jl GOC:tb GOC:vw negative regulation of enzyme activity GOC:tb Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. establishment and maintenance of translational machinery localization establishment and maintenance of translational protein localization regulation of translation by machinery localisation translational machinery localization translational protein localization biological_process GO:0043143 regulation of translation by machinery localization GO:0043143 Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. GOC:jl regulation of translation by machinery localisation GOC:mah translational machinery localization GOC:dph GOC:tb The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 biopolymer metabolic process macromolecule metabolism organismal macromolecule metabolism multicellular organismal macromolecule metabolic process biological_process GO:0043170 macromolecule metabolic process GO:0043170 The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:mah biopolymer metabolic process GOC:mtg_chebi_dec09 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. biological_process GO:0043207 response to external biotic stimulus GO:0043207 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. GOC:go_curators Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. NIF_Subcellular:sao1539965131 Wikipedia:Organelle cellular_component GO:0043226 organelle GO:0043226 Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. GOC:go_curators Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. NIF_Subcellular:sao414196390 membrane-enclosed organelle cellular_component GO:0043227 membrane-bounded organelle GO:0043227 Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. GOC:go_curators Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. https://github.com/geneontology/go-ontology/issues/21881 NIF_Subcellular:sao1456184038 non-membrane-enclosed organelle cellular_component biological condensate GO:0043228 non-membrane-bounded organelle GO:0043228 Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. GOC:go_curators Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. cellular_component GO:0043229 intracellular organelle GO:0043229 Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GOC:go_curators Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. cellular_component GO:0043230 extracellular organelle GO:0043230 Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. GOC:jl PMID:9914479 Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. intracellular membrane-enclosed organelle cellular_component GO:0043231 intracellular membrane-bounded organelle GO:0043231 Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. GOC:go_curators Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. intracellular non-membrane-enclosed organelle cellular_component GO:0043232 intracellular non-membrane-bounded organelle GO:0043232 Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. down regulation of protein complex disassembly down-regulation of protein complex disassembly downregulation of protein complex disassembly inhibition of protein complex disassembly biological_process negative regulation of protein complex disassembly GO:0043242 negative regulation of protein-containing complex disassembly GO:0043242 Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GOC:jl Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. up regulation of protein complex disassembly up-regulation of protein complex disassembly upregulation of protein complex disassembly activation of protein complex disassembly stimulation of protein complex disassembly biological_process positive regulation of protein complex disassembly GO:0043243 positive regulation of protein-containing complex disassembly GO:0043243 Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GOC:jl Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. biological_process regulation of protein complex disassembly GO:0043244 regulation of protein-containing complex disassembly GO:0043244 Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GOC:jl Any process that modulates the frequency, rate or extent of protein complex assembly. biological_process regulation of protein complex assembly GO:0043254 regulation of protein-containing complex assembly GO:0043254 Any process that modulates the frequency, rate or extent of protein complex assembly. GOC:jl The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. mycotoxin metabolism biological_process GO:0043385 mycotoxin metabolic process GO:0043385 The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. GOC:jl The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus. mycotoxin anabolism mycotoxin biosynthesis mycotoxin formation mycotoxin synthesis biological_process GO:0043386 mycotoxin biosynthetic process GO:0043386 The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus. GOC:jl The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. https://github.com/geneontology/go-ontology/issues/26424 biological_process GO:0043412 macromolecule modification GO:0043412 The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. GOC:go_curators The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). keto acid metabolic process keto acid metabolism ketoacid metabolic process ketoacid metabolism oxo acid metabolic process oxo acid metabolism oxoacid metabolism biological_process GO:0043436 oxoacid metabolic process GO:0043436 The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). Wikipedia:Oxyacid The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. biological_process GO:0043473 pigmentation GO:0043473 The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. GOC:jl The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. pigment accumulation in response to external stimulus biological_process GO:0043476 pigment accumulation GO:0043476 The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. GOC:jl The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus. biological_process GO:0043482 cellular pigment accumulation GO:0043482 The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus. GOC:jl Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. biological_process GO:0043549 regulation of kinase activity GO:0043549 Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GOC:bf The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. amide metabolism cellular amide metabolic process biological_process GO:0043603 amide metabolic process GO:0043603 The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. GOC:curators The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. biological_process GO:0043604 amide biosynthetic process GO:0043604 The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. GOC:curators Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. https://github.com/geneontology/go-ontology/issues/22580 mah 2010-09-08T10:01:42Z GO:0034600 GO:0034621 GO:0071822 protein complex subunit organisation protein complex subunit organization biological_process cellular macromolecular complex organization cellular macromolecular complex subunit organisation cellular macromolecular complex subunit organization macromolecular complex organization macromolecular complex subunit organisation macromolecular complex subunit organization protein-containing complex subunit organization GO:0043933 protein-containing complex organization GO:0043933 Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. GOC:mah protein complex subunit organisation GOC:mah The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. Wikipedia:Spore biological_process GO:0043934 sporulation GO:0043934 The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. GOC:pamgo_curators The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. biological_process GO:0043935 sexual sporulation resulting in formation of a cellular spore GO:0043935 The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. GOC:pamgo_curators The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. asexual sporulation resulting in the formation of a viable spore asexual reproduction resulting in the formation of a cellular spore biological_process GO:0043936 asexual sporulation resulting in formation of a cellular spore GO:0043936 The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. GOC:pamgo_curators asexual sporulation resulting in the formation of a viable spore GOC:di asexual reproduction resulting in the formation of a cellular spore GOC:di The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. migration within host biological_process GO:0044001 migration in host GO:0044001 The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:cc A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. GO:0071843 cellular component biogenesis at cellular level biological_process GO:0044085 cellular component biogenesis GO:0044085 A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. GOC:jl GOC:mah Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. biological_process GO:0044087 regulation of cellular component biogenesis GO:0044087 Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. GOC:jl Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. regulation of vacuole organisation biological_process regulation of vacuole biogenesis GO:0044088 regulation of vacuole organization GO:0044088 Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. GOC:jl GOC:mah regulation of vacuole organisation GOC:mah regulation of vacuole biogenesis GOC:mah Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. biological_process GO:0044089 positive regulation of cellular component biogenesis GO:0044089 Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. GOC:jl Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. positive regulation of vacuole organisation biological_process positive regulation of vacuole biogenesis GO:0044090 positive regulation of vacuole organization GO:0044090 Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. GOC:jl GOC:mah positive regulation of vacuole organisation GOC:mah positive regulation of vacuole biogenesis GOC:mah A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. biological_process GO:0044091 membrane biogenesis GO:0044091 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. GOC:jl Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. jl 2009-04-21T04:07:27Z biological_process GO:0044092 negative regulation of molecular function GO:0044092 Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GO:jl Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. jl 2009-04-21T04:11:06Z biological_process GO:0044093 positive regulation of molecular function GO:0044093 Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GO:jl The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. https://github.com/geneontology/go-ontology/issues/20305 jl 2009-07-30T02:26:46Z GO:0044115 GO:0044152 development on or near surface of other organism involved in symbiotic interaction biological_process development during symbiotic interaction development involved in symbiotic interaction development of symbiont during interaction with host development of symbiont involved in interaction with host development on or near surface of other organism during symbiotic interaction GO:0044111 formation of structure involved in a symbiotic process GO:0044111 The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. GO:jl GOC:pamgo_curators development during symbiotic interaction GOC:dph development of symbiont during interaction with host GOC:dph development on or near surface of other organism during symbiotic interaction GOC:dph The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. jl 2009-07-30T03:39:25Z GO:0044122 GO:0044124 development of symbiont in host intercellular space development of symbiont in host vascular tissue biological_process GO:0044114 This term partially replaces the obsolete term 'growth or development of symbiont in host ; GO:0044412'. See also 'biological process involved in interaction with host ; GO:0051701. development of symbiont in host GO:0044114 The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:jl GOC:pamgo_curators A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). jl 2009-10-22T02:38:55Z translation initiation (ternary) complex Met-tRNA/eIF2.GTP ternary complex cellular_component GO:0044207 translation initiation ternary complex GO:0044207 A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). GOC:jl The chemical reactions and pathways by which individual cells transform chemical substances. cellular metabolism biological_process intermediary metabolism GO:0044237 This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. cellular metabolic process GO:0044237 The chemical reactions and pathways by which individual cells transform chemical substances. GOC:go_curators intermediary metabolism GOC:mah The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. https://github.com/geneontology/go-ontology/issues/26424 Wikipedia:Primary_metabolite primary metabolism biological_process GO:0044238 primary metabolic process GO:0044238 The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. GOC:go_curators The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. GOC:go_curators http://www.metacyc.org The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. cellular breakdown cellular catabolism cellular degradation biological_process GO:0044248 cellular catabolic process GO:0044248 The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. GOC:jl The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. https://github.com/geneontology/go-ontology/issues/27052 cellular anabolism cellular biosynthesis cellular formation cellular synthesis biological_process GO:0044249 This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. cellular biosynthetic process GO:0044249 The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GOC:jl The chemical reactions and pathways involving lipids, as carried out by individual cells. cellular lipid metabolism biological_process GO:0044255 cellular lipid metabolic process GO:0044255 The chemical reactions and pathways involving lipids, as carried out by individual cells. GOC:jl The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. nitrogen compound anabolism nitrogen compound biosynthesis nitrogen compound formation nitrogen compound synthesis biological_process GO:0044271 cellular nitrogen compound biosynthetic process GO:0044271 The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. GOC:jl ISBN:0198506732 The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. jl 2010-01-26T12:05:20Z small molecule metabolism biological_process GO:0044281 Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. small molecule metabolic process GO:0044281 The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. GOC:curators GOC:pde GOC:vw The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. jl 2010-01-26T12:06:49Z small molecule biosynthesis biological_process GO:0044283 Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. small molecule biosynthetic process GO:0044283 The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. GOC:curators GOC:pde GOC:vw A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. https://github.com/geneontology/go-ontology/issues/14807 https://github.com/geneontology/go-ontology/issues/20191 GO:0043298 GO:0044404 GO:0072519 GO:0085031 commensalism host-pathogen interaction parasitism biological_process symbiosis symbiosis, encompassing mutualism through parasitism symbiotic interaction symbiotic interaction between host and organism symbiotic interaction between organisms symbiotic interaction between species symbiotic process GO:0044403 biological process involved in symbiotic interaction symbiosis, encompassing mutualism through parasitism GO:0044403 A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. GOC:cc PMID:31257129 Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. https://github.com/geneontology/go-ontology/issues/18563 GO:0030260 GO:0044411 GO:0051806 GO:0051828 GO:0051830 GO:0075052 GO:0085027 GO:0085028 entry into host host invasion host penetration invasion into host invasion of host penetration into host entry into cell of other organism during symbiotic interaction entry into host cell via penetration peg entry into host via a specialized structure during symbiotic interaction entry into host via enzymatic degradation of host anatomical structure entry into host via enzymatic degradation of host cuticle penetration into host via a specialized structure penetration into host via a specialized structure during symbiotic interaction biological_process entry into cell of other organism involved in symbiotic interaction entry into host through host barriers entry into other organism during symbiotic interaction entry into other organism involved in symbiotic interaction invasion into other organism invasion of other organism invasive growth other organism invasion GO:0044409 entry into host symbiont entry into host GO:0044409 Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:vw host penetration GOC:vw penetration into host GOC:vw entry into cell of other organism during symbiotic interaction GOC:tb penetration into host via a specialized structure GOC:vw penetration into host via a specialized structure during symbiotic interaction GOC:vw entry into other organism during symbiotic interaction GOC:tb Any process evolved to enable an interaction with an organism of a different species. https://github.com/geneontology/go-ontology/issues/20191 interaction with another species interspecies interaction interspecies interaction between organisms interspecies interaction with other organisms biological_process GO:0044419 biological process involved in interspecies interaction between organisms GO:0044419 Any process evolved to enable an interaction with an organism of a different species. GOC:cc OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. cellular subcomponent cellular_component protoplast GO:0044464 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. obsolete cell part true GO:0044464 OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. GOC:jl cellular subcomponent NIF_Subcellular:sao628508602 protoplast GOC:mah The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. jl 2012-03-29T01:55:18Z secondary metabolite biosynthesis biological_process GO:0044550 secondary metabolite biosynthetic process GO:0044550 The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. GOC:jl A distinct period or stage in a biological process or cycle. jl 2014-07-16T13:12:40Z biological_process GO:0044848 Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase. biological phase GO:0044848 A distinct period or stage in a biological process or cycle. GOC:jl Binding to a macromolecular complex. jl 2014-12-16T11:38:58Z GO:0032403 protein complex binding molecular_function macromolecular complex binding GO:0044877 protein-containing complex binding GO:0044877 Binding to a macromolecular complex. GOC:jl Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0002226 Wikipedia:Innate_immune_system innate immunity nonspecific immune response biological_process GO:0045087 innate immune response GO:0045087 Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GOC:add GOC:ebc GOC:mtg_sensu GO_REF:0000022 innate immunity GOC:pg The directed movement of a protein to a specific location. establishment of protein localisation protein positioning protein recruitment biological_process GO:0045184 establishment of protein localization GO:0045184 The directed movement of a protein to a specific location. GOC:bf establishment of protein localisation GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. external encapsulating structure organisation external encapsulating structure organization and biogenesis biological_process GO:0045229 external encapsulating structure organization GO:0045229 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. GOC:ai GOC:dph GOC:jl GOC:mah external encapsulating structure organization and biogenesis GOC:dph GOC:jl GOC:mah Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. biological_process GO:0045595 regulation of cell differentiation GO:0045595 Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. down regulation of cell differentiation down-regulation of cell differentiation downregulation of cell differentiation inhibition of cell differentiation biological_process GO:0045596 negative regulation of cell differentiation GO:0045596 Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. GOC:go_curators Any process that activates or increases the frequency, rate or extent of cell differentiation. up regulation of cell differentiation up-regulation of cell differentiation upregulation of cell differentiation activation of cell differentiation stimulation of cell differentiation biological_process GO:0045597 positive regulation of cell differentiation GO:0045597 Any process that activates or increases the frequency, rate or extent of cell differentiation. GOC:go_curators Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0045946 positive regulation of protein anabolism positive regulation of protein biosynthesis positive regulation of protein biosynthetic process positive regulation of protein formation positive regulation of protein synthesis up regulation of protein biosynthetic process up-regulation of protein biosynthetic process upregulation of protein biosynthetic process activation of protein biosynthetic process stimulation of protein biosynthetic process biological_process GO:0045727 positive regulation of translation GO:0045727 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GOC:dph GOC:go_curators GOC:tb positive regulation of protein biosynthetic process GOC:tb A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Wikipedia:Respiratory_burst metabolic burst oxidative burst biological_process GO:0045730 respiratory burst GO:0045730 A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. ISBN:0198506732 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. down regulation of amino acid metabolic process down-regulation of amino acid metabolic process downregulation of amino acid metabolic process negative regulation of amino acid metabolism inhibition of amino acid metabolic process biological_process GO:0045763 negative regulation of cellular amino acid metabolic process GO:0045763 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. GOC:go_curators Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. positive regulation of amino acid metabolism positive regulation of cellular amino acid metabolic process up regulation of amino acid metabolic process up-regulation of amino acid metabolic process upregulation of amino acid metabolic process activation of amino acid metabolic process stimulation of amino acid metabolic process biological_process GO:0045764 positive regulation of amino acid metabolic process GO:0045764 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. GOC:go_curators Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. down regulation of progression through cell cycle down-regulation of progression through cell cycle downregulation of progression through cell cycle negative regulation of cell cycle progression negative regulation of progression through cell cycle inhibition of progression through cell cycle biological_process GO:0045786 negative regulation of cell cycle GO:0045786 Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. GOC:dph GOC:go_curators GOC:tb Any process that activates or increases the rate or extent of progression through the cell cycle. positive regulation of cell cycle progression positive regulation of progression through cell cycle up regulation of progression through cell cycle up-regulation of progression through cell cycle upregulation of progression through cell cycle activation of progression through cell cycle stimulation of progression through cell cycle biological_process GO:0045787 positive regulation of cell cycle GO:0045787 Any process that activates or increases the rate or extent of progression through the cell cycle. GOC:go_curators positive regulation of progression through cell cycle GOC:dph GOC:tb Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. down regulation of meiosis down-regulation of meiosis downregulation of meiosis negative regulation of meiosis inhibition of meiosis biological_process GO:0045835 negative regulation of meiotic nuclear division GO:0045835 Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. GOC:go_curators Any process that activates or increases the frequency, rate or extent of meiosis. positive regulation of meiosis up regulation of meiosis up-regulation of meiosis upregulation of meiosis activation of meiosis stimulation of meiosis biological_process GO:0045836 positive regulation of meiotic nuclear division GO:0045836 Any process that activates or increases the frequency, rate or extent of meiosis. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. down regulation of translational elongation down-regulation of translational elongation downregulation of translational elongation inhibition of translational elongation biological_process GO:0045900 negative regulation of translational elongation GO:0045900 Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. GOC:go_curators Any process that activates or increases the frequency, rate or extent of translational elongation. up regulation of translational elongation up-regulation of translational elongation upregulation of translational elongation activation of translational elongation stimulation of translational elongation biological_process GO:0045901 positive regulation of translational elongation GO:0045901 Any process that activates or increases the frequency, rate or extent of translational elongation. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. down regulation of translational termination down-regulation of translational termination downregulation of translational termination inhibition of translational termination biological_process GO:0045904 negative regulation of translational termination GO:0045904 Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. GOC:go_curators Any process that activates or increases the frequency, rate or extent of translational termination. up regulation of translational termination up-regulation of translational termination upregulation of translational termination activation of translational termination stimulation of translational termination biological_process GO:0045905 positive regulation of translational termination GO:0045905 Any process that activates or increases the frequency, rate or extent of translational termination. GOC:go_curators Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process biological_process negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0045934 negative regulation of nucleobase-containing compound metabolic process GO:0045934 Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GOC:go_curators negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GOC:dph GOC:tb Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process biological_process positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0045935 positive regulation of nucleobase-containing compound metabolic process GO:0045935 Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GOC:go_curators positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GOC:dph GOC:tb Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. down regulation of phosphate metabolic process down-regulation of phosphate metabolic process downregulation of phosphate metabolic process negative regulation of phosphate metabolism inhibition of phosphate metabolic process biological_process GO:0045936 negative regulation of phosphate metabolic process GO:0045936 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. GOC:go_curators Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. positive regulation of phosphate metabolism up regulation of phosphate metabolic process up-regulation of phosphate metabolic process upregulation of phosphate metabolic process activation of phosphate metabolic process stimulation of phosphate metabolic process biological_process GO:0045937 positive regulation of phosphate metabolic process GO:0045937 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. down regulation of translational initiation down-regulation of translational initiation downregulation of translational initiation inhibition of translational initiation biological_process GO:0045947 negative regulation of translational initiation GO:0045947 Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. GOC:go_curators Any process that activates or increases the frequency, rate or extent of translational initiation. up regulation of translational initiation up-regulation of translational initiation upregulation of translational initiation activation of translational initiation stimulation of translational initiation biological_process GO:0045948 positive regulation of translational initiation GO:0045948 Any process that activates or increases the frequency, rate or extent of translational initiation. GOC:go_curators Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. down regulation of embryonic development down-regulation of embryonic development downregulation of embryonic development inhibition of embryonic development biological_process GO:0045992 negative regulation of embryonic development GO:0045992 Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. GOC:go_curators Any process that modulates the frequency, rate or extent of embryonic development. biological_process GO:0045995 regulation of embryonic development GO:0045995 Any process that modulates the frequency, rate or extent of embryonic development. GOC:go_curators The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. nucleobase anabolism nucleobase biosynthesis nucleobase formation nucleobase synthesis biological_process GO:0046112 nucleobase biosynthetic process GO:0046112 The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. GOC:ai The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. alcohol anabolism alcohol biosynthesis alcohol formation alcohol synthesis biological_process GO:0046165 alcohol biosynthetic process GO:0046165 The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. GOC:ai The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. polyhydric alcohol biosynthetic process polyol anabolism polyol biosynthesis polyol formation polyol synthesis biological_process GO:0046173 polyol biosynthetic process GO:0046173 The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. GOC:curators The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. carboxylic acid anabolism carboxylic acid biosynthesis carboxylic acid formation carboxylic acid synthesis biological_process GO:0046394 carboxylic acid biosynthetic process GO:0046394 The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. ISBN:0198506732 The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). heterocycle metabolism biological_process GO:0046483 heterocycle metabolic process GO:0046483 The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). ISBN:0198506732 The controlled release of a substance by a cell or a tissue. biological_process GO:0046903 secretion GO:0046903 The controlled release of a substance by a cell or a tissue. GOC:ai The directed movement of substances within a cell. jl 2013-12-18T14:04:50Z GO:1902582 biological_process single organism intracellular transport single-organism intracellular transport GO:0046907 intracellular transport GO:0046907 The directed movement of substances within a cell. GOC:ai single organism intracellular transport GOC:TermGenie The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). biological_process GO:0046942 carboxylic acid transport GO:0046942 The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). GOC:ai Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. molecular_function GO:0048029 monosaccharide binding GO:0048029 Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. GOC:jid A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. autophagic death programmed cell death by autophagy programmed cell death by macroautophagy biological_process autosis type II programmed cell death GO:0048102 The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not. autophagic cell death GO:0048102 A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. GOC:autophagy GOC:mah GOC:mtg_apoptosis PMID:18846107 PMID:23347517 programmed cell death by autophagy GOC:pr programmed cell death by macroautophagy GOC:cjm autosis PMID:25236395 type II programmed cell death GOC:sl The creation of two or more organelles by division of one organelle. biological_process GO:0048285 organelle fission GO:0048285 The creation of two or more organelles by division of one organelle. GOC:jid The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. https://github.com/geneontology/go-ontology/issues/24390 biological_process terminal differentiation GO:0048468 cell development GO:0048468 The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. GOC:go_curators terminal differentiation GOC:dph GOC:tb Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. https://github.com/geneontology/go-ontology/issues/25943 Wikipedia:Organogenesis development of an organ organogenesis biological_process GO:0048513 animal organ development GO:0048513 Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GOC:dph GOC:jid Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0043119 positive regulation of physiological process up regulation of biological process up-regulation of biological process upregulation of biological process activation of biological process stimulation of biological process biological_process GO:0048518 positive regulation of biological process GO:0048518 Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GOC:jid Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0043118 down regulation of biological process down-regulation of biological process downregulation of biological process negative regulation of physiological process inhibition of biological process biological_process GO:0048519 negative regulation of biological process GO:0048519 Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GOC:jid Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0051242 positive regulation of cellular physiological process up regulation of cellular process up-regulation of cellular process upregulation of cellular process activation of cellular process stimulation of cellular process biological_process GO:0048522 positive regulation of cellular process GO:0048522 Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GOC:jid Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0051243 down regulation of cellular process down-regulation of cellular process downregulation of cellular process negative regulation of cellular physiological process inhibition of cellular process biological_process GO:0048523 negative regulation of cellular process GO:0048523 Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GOC:jid Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. biological_process GO:0048580 regulation of post-embryonic development GO:0048580 Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GOC:jid Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. down regulation of post-embryonic development down-regulation of post-embryonic development downregulation of post-embryonic development inhibition of post-embryonic development biological_process GO:0048581 negative regulation of post-embryonic development GO:0048581 Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GOC:jid Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. up regulation of post-embryonic development up-regulation of post-embryonic development upregulation of post-embryonic development activation of post-embryonic development stimulation of post-embryonic development biological_process GO:0048582 positive regulation of post-embryonic development GO:0048582 Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GOC:jid The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. biological_process GO:0048589 developmental growth GO:0048589 The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. GOC:go_curators The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. formation of an anatomical structure involved in morphogenesis biological_process GO:0048646 Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. anatomical structure formation involved in morphogenesis GO:0048646 The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GOC:dph GOC:jid GOC:tb formation of an anatomical structure involved in morphogenesis GOC:dph GOC:tb The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 anatomical structure development GO:0048856 The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GO_REF:0000021 A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. biological_process GO:0048869 cellular developmental process GO:0048869 A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. GOC:isa_complete The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0050657 nucleic acid transport GO:0050657 The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai ISBN:0198506732 The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0050658 RNA transport GO:0050658 The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. biological_process GO:0050708 regulation of protein secretion GO:0050708 Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. down regulation of protein secretion down-regulation of protein secretion downregulation of protein secretion inhibition of protein secretion biological_process GO:0050709 negative regulation of protein secretion GO:0050709 Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. GOC:ai Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. up regulation of protein secretion up-regulation of protein secretion upregulation of protein secretion activation of protein secretion stimulation of protein secretion biological_process GO:0050714 positive regulation of protein secretion GO:0050714 Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. GOC:ai Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0050791 regulation of physiological process biological_process GO:0050789 regulation of biological process GO:0050789 Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GOC:ai GOC:go_curators Any process that modulates the activity of an enzyme. GO:0048552 regulation of enzyme activity regulation of metalloenzyme activity biological_process GO:0050790 regulation of catalytic activity GO:0050790 Any process that modulates the activity of an enzyme. GOC:ai GOC:ebc GOC:vw Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). biological_process GO:0050793 regulation of developmental process GO:0050793 Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GOC:go_curators Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0051244 regulation of cellular physiological process biological_process GO:0050794 regulation of cellular process GO:0050794 Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GOC:go_curators Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GO:0051869 physiological response to stimulus biological_process GO:0050896 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus GO:0050896 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GOC:ai GOC:bf Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. biological_process GO:0051046 regulation of secretion GO:0051046 Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GOC:ai Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. up regulation of secretion up-regulation of secretion upregulation of secretion activation of secretion stimulation of secretion biological_process GO:0051047 positive regulation of secretion GO:0051047 Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. down regulation of secretion down-regulation of secretion downregulation of secretion inhibition of secretion biological_process GO:0051048 negative regulation of secretion GO:0051048 Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GOC:ai Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0051049 regulation of transport GO:0051049 Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. up regulation of transport up-regulation of transport upregulation of transport activation of transport stimulation of transport biological_process GO:0051050 positive regulation of transport GO:0051050 Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of transport down-regulation of transport downregulation of transport inhibition of transport biological_process GO:0051051 negative regulation of transport GO:0051051 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. biological_process meiotic nuclear envelope breakdown meiotic nuclear envelope catabolism meiotic nuclear envelope degradation meiotic nuclear envelope disassembly GO:0051078 meiotic nuclear membrane disassembly GO:0051078 The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. GOC:bf The controlled breakdown of the nuclear membranes, for example during cellular division. biological_process nuclear envelope breakdown nuclear envelope catabolism nuclear envelope degradation nuclear envelope disassembly GO:0051081 nuclear membrane disassembly GO:0051081 The controlled breakdown of the nuclear membranes, for example during cellular division. GOC:ai Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). down regulation of developmental process down-regulation of developmental process downregulation of developmental process inhibition of developmental process biological_process GO:0051093 negative regulation of developmental process GO:0051093 Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GOC:ai Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). up regulation of developmental process up-regulation of developmental process upregulation of developmental process activation of developmental process stimulation of developmental process biological_process GO:0051094 positive regulation of developmental process GO:0051094 Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GOC:ai Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. regulation of cellular component organisation biological_process regulation of cell organisation regulation of cell organization regulation of cellular component organization and biogenesis GO:0051128 regulation of cellular component organization GO:0051128 Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GOC:ai regulation of cell organisation GOC:mah regulation of cell organization GOC:mah regulation of cellular component organization and biogenesis GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. down regulation of cell organization down-regulation of cell organization downregulation of cell organization inhibition of cell organization biological_process negative regulation of cell organisation negative regulation of cellular component organization and biogenesis GO:0051129 negative regulation of cellular component organization GO:0051129 Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GOC:ai negative regulation of cell organisation GOC:mah negative regulation of cellular component organization and biogenesis GOC:mah Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. positive regulation of cell organisation up regulation of cell organization up-regulation of cell organization upregulation of cell organization activation of cell organization stimulation of cell organization biological_process positive regulation of cellular component organization and biogenesis GO:0051130 positive regulation of cellular component organization GO:0051130 Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GOC:ai positive regulation of cellular component organization and biogenesis GOC:mah The directed movement of substances into, out of, or within the nucleus. Wikipedia:Nuclear_transport nucleus transport biological_process GO:0051169 nuclear transport GO:0051169 The directed movement of substances into, out of, or within the nucleus. GOC:ai Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. regulation of nitrogen metabolic process regulation of nitrogen metabolism biological_process GO:0051171 regulation of nitrogen compound metabolic process GO:0051171 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. GOC:ai GOC:tb regulation of nitrogen metabolic process GOC:tb Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. down regulation of nitrogen metabolic process down-regulation of nitrogen metabolic process downregulation of nitrogen metabolic process negative regulation of nitrogen metabolic process negative regulation of nitrogen metabolism inhibition of nitrogen metabolic process biological_process GO:0051172 negative regulation of nitrogen compound metabolic process GO:0051172 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. GOC:ai GOC:tb negative regulation of nitrogen metabolic process GOC:tb Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. positive regulation of nitrogen metabolic process positive regulation of nitrogen metabolism up regulation of nitrogen metabolic process up-regulation of nitrogen metabolic process upregulation of nitrogen metabolic process activation of nitrogen metabolic process stimulation of nitrogen metabolic process biological_process GO:0051173 positive regulation of nitrogen compound metabolic process GO:0051173 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. GOC:ai GOC:tb positive regulation of nitrogen metabolic process GOC:tb Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. regulation of phosphorus metabolism biological_process GO:0051174 regulation of phosphorus metabolic process GO:0051174 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. GOC:ai Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. https://github.com/geneontology/go-ontology/issues/27052 jl 2013-12-18T13:51:04Z GO:1902578 establishment and maintenance of localization establishment and maintenance of position localisation establishment and maintenance of cellular component location establishment and maintenance of substance location establishment and maintenance of substrate location biological_process single organism localization single-organism localization GO:0051179 localization GO:0051179 Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. GOC:ai GOC:dos localisation GOC:mah single organism localization GOC:TermGenie Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. up regulation of protein transport up-regulation of protein transport upregulation of protein transport activation of protein transport stimulation of protein transport biological_process GO:0051222 positive regulation of protein transport GO:0051222 Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0051223 regulation of protein transport GO:0051223 Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of protein transport down-regulation of protein transport downregulation of protein transport inhibition of protein transport biological_process GO:0051224 negative regulation of protein transport GO:0051224 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. https://github.com/geneontology/go-ontology/issues/24200 establishment of localisation biological_process GO:0051234 establishment of localization GO:0051234 Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GOC:ai GOC:dos establishment of localisation GOC:mah The directed movement of RNA to a specific location. RNA positioning RNA recruitment establishment of RNA localisation biological_process GO:0051236 establishment of RNA localization GO:0051236 The directed movement of RNA to a specific location. GOC:ai establishment of RNA localisation GOC:mah Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. biological_process GO:0051239 regulation of multicellular organismal process GO:0051239 Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. GOC:ai GOC:dph GOC:tb Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. up regulation of multicellular organismal process up-regulation of multicellular organismal process upregulation of multicellular organismal process activation of multicellular organismal process stimulation of multicellular organismal process biological_process GO:0051240 positive regulation of multicellular organismal process GO:0051240 Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. down regulation of multicellular organismal process down-regulation of multicellular organismal process downregulation of multicellular organismal process inhibition of multicellular organismal process biological_process GO:0051241 negative regulation of multicellular organismal process GO:0051241 Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. GOC:ai Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. https://github.com/geneontology/go-ontology/issues/23112 GO:0032268 regulation of protein metabolism biological_process regulation of cellular protein metabolic process regulation of cellular protein metabolism GO:0051246 regulation of protein metabolic process GO:0051246 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. GOC:ai Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. https://github.com/geneontology/go-ontology/issues/23112 GO:0032270 positive regulation of cellular protein metabolic process positive regulation of cellular protein metabolism positive regulation of protein metabolism up regulation of cellular protein metabolic process up regulation of protein metabolic process up-regulation of cellular protein metabolic process up-regulation of protein metabolic process upregulation of cellular protein metabolic process upregulation of protein metabolic process activation of cellular protein metabolic process activation of protein metabolic process stimulation of cellular protein metabolic process stimulation of protein metabolic process biological_process GO:0051247 positive regulation of protein metabolic process GO:0051247 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. https://github.com/geneontology/go-ontology/issues/23112 GO:0032269 down regulation of cellular protein metabolic process down regulation of protein metabolic process down-regulation of cellular protein metabolic process down-regulation of protein metabolic process downregulation of cellular protein metabolic process downregulation of protein metabolic process negative regulation of cellular protein metabolic process negative regulation of cellular protein metabolism negative regulation of protein metabolism inhibition of cellular protein metabolic process inhibition of protein metabolic process biological_process GO:0051248 negative regulation of protein metabolic process GO:0051248 Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. GOC:ai Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. regulation of RNA metabolism biological_process GO:0051252 regulation of RNA metabolic process GO:0051252 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. down regulation of RNA metabolic process down-regulation of RNA metabolic process downregulation of RNA metabolic process negative regulation of RNA metabolism inhibition of RNA metabolic process biological_process GO:0051253 negative regulation of RNA metabolic process GO:0051253 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. GOC:ai Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. positive regulation of RNA metabolism up regulation of RNA metabolic process up-regulation of RNA metabolic process upregulation of RNA metabolic process activation of RNA metabolic process stimulation of RNA metabolic process biological_process GO:0051254 positive regulation of RNA metabolic process GO:0051254 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. GOC:ai Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. https://github.com/geneontology/go-ontology/issues/24599 GO:0007126 Wikipedia:Meiosis biological_process meiosis GO:0051321 Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. meiotic cell cycle GO:0051321 Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. GOC:ai The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. Wikipedia:Telophase biological_process GO:0051326 note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). telophase GO:0051326 The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. GOC:mtg_cell_cycle A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. M phase of meiotic cell cycle biological_process GO:0051327 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). meiotic M phase GO:0051327 A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. GOC:mtg_cell_cycle Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. transferase regulator biological_process GO:0051338 This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. regulation of transferase activity GO:0051338 Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. GOC:ai Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. transferase activator up regulation of transferase activity up-regulation of transferase activity upregulation of transferase activity activation of transferase activity stimulation of transferase activity biological_process GO:0051347 This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. positive regulation of transferase activity GO:0051347 Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. GOC:ai Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. down regulation of transferase activity down-regulation of transferase activity downregulation of transferase activity transferase inhibitor inhibition of transferase activity biological_process GO:0051348 This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. negative regulation of transferase activity GO:0051348 Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. GOC:ai Any process that modulates the rate or extent of progression through the meiotic cell cycle. meiotic cell cycle modulation meiotic cell cycle regulation modulation of meiotic cell cycle progression regulation of meiotic cell cycle progression regulation of progression through meiotic cell cycle biological_process meiotic cell cycle regulator GO:0051445 regulation of meiotic cell cycle GO:0051445 Any process that modulates the rate or extent of progression through the meiotic cell cycle. GOC:ai GOC:dph GOC:tb regulation of progression through meiotic cell cycle GOC:dph GOC:tb Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. positive regulation of meiotic cell cycle progression positive regulation of progression through meiotic cell cycle up regulation of progression through meiotic cell cycle up-regulation of progression through meiotic cell cycle upregulation of progression through meiotic cell cycle activation of progression through meiotic cell cycle stimulation of progression through meiotic cell cycle biological_process GO:0051446 positive regulation of meiotic cell cycle GO:0051446 Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. GOC:ai GOC:dph GOC:tb positive regulation of progression through meiotic cell cycle GOC:dph GOC:tb Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. down regulation of progression through meiotic cell cycle down-regulation of progression through meiotic cell cycle downregulation of progression through meiotic cell cycle negative regulation of meiotic cell cycle progression negative regulation of progression through meiotic cell cycle inhibition of progression through meiotic cell cycle biological_process GO:0051447 negative regulation of meiotic cell cycle GO:0051447 Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. GOC:ai GOC:dph GOC:tb negative regulation of progression through meiotic cell cycle GOC:dph GOC:tb Any process in which an organelle is transported to, and/or maintained in, a specific location. https://github.com/geneontology/go-ontology/issues/19809 establishment and maintenance of organelle localization organelle localisation biological_process GO:0051640 organelle localization GO:0051640 Any process in which an organelle is transported to, and/or maintained in, a specific location. GOC:ai organelle localisation GOC:mah A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. https://github.com/geneontology/go-ontology/issues/27189 jl 2013-12-18T14:04:32Z GO:1902580 cellular localisation establishment and maintenance of cellular localization establishment and maintenance of localization in cell or cell membrane single organism cellular localization intracellular localization localization within cell biological_process single-organism cellular localization GO:0051641 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. cellular localization GO:0051641 A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. GOC:tb GOC:vw cellular localisation GOC:mah single organism cellular localization GOC:TermGenie Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. cell nucleus localization establishment and maintenance of nucleus localization localization of nucleus nucleus localisation biological_process GO:0051647 nucleus localization GO:0051647 Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. GOC:ai nucleus localisation GOC:mah Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. establishment of localisation in cell establishment of intracellular localization establishment of localization within cell positioning within cell biological_process establishment of cellular localization GO:0051649 establishment of localization in cell GO:0051649 Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GOC:ai GOC:dos GOC:dph GOC:tb Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GOC:ai GOC:dos GOC:dph GOC:tb establishment of localisation in cell GOC:mah establishment of cellular localization GOC:dph GOC:tb The directed movement of an organelle to a specific location. establishment of organelle localisation biological_process GO:0051656 establishment of organelle localization GO:0051656 The directed movement of an organelle to a specific location. GOC:ai establishment of organelle localisation GOC:mah Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. establishment and maintenance of localization in membrane establishment and maintenance of position in membrane localisation within membrane localization to membrane positioning within membrane biological_process GO:0051668 localization within membrane GO:0051668 Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. GOC:ai localisation within membrane GOC:mah Any process in which a cell is transported to, and/or maintained in, a specific location. cell localization establishment and maintenance of cell localization establishment and maintenance of localization of cell localisation of cell biological_process GO:0051674 localization of cell GO:0051674 Any process in which a cell is transported to, and/or maintained in, a specific location. GOC:ai localisation of cell GOC:mah An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. https://github.com/geneontology/go-ontology/issues/20191 GO:0044112 GO:0044116 GO:0044117 GO:0044119 GO:0044121 GO:0044123 GO:0044125 interaction with host growth of symbiont in host growth of symbiont in host cell growth of symbiont in host organelle growth of symbiont in host vacuole biological_process GO:0051701 biological process involved in interaction with host GO:0051701 An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. GOC:cc GO:0051704 A biological process which involves another organism of the same or different species. multi-organism process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. GO:0009613 GO:0042828 biological_process GO:0051707 response to other organism GO:0051707 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. GOC:ai Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. biological_process GO:0051716 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. cellular response to stimulus GO:0051716 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. GOC:bf GOC:jl Any process that modulates the rate or extent of progression through the cell cycle. GO:0000074 GO:0007050 GO:0071156 GO:0071157 GO:0071158 GO:0071850 cell cycle modulation cell cycle regulation control of cell cycle progression modulation of cell cycle progression regulation of cell cycle progression regulation of progression through cell cycle arrest of mitotic cell cycle progression cell cycle arrest mitotic cell cycle arrest negative regulation of cell cycle arrest positive regulation of cell cycle arrest regulation of cell cycle arrest biological_process cell cycle regulator tumor suppressor GO:0051726 regulation of cell cycle GO:0051726 Any process that modulates the rate or extent of progression through the cell cycle. GOC:ai GOC:dph GOC:tb arrest of mitotic cell cycle progression GOC:mah Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. biological_process GO:0051783 regulation of nuclear division GO:0051783 Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. down regulation of nuclear division down-regulation of nuclear division downregulation of nuclear division inhibition of nuclear division biological_process GO:0051784 negative regulation of nuclear division GO:0051784 Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. GOC:ai Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. up regulation of nuclear division up-regulation of nuclear division upregulation of nuclear division activation of nuclear division stimulation of nuclear division biological_process GO:0051785 positive regulation of nuclear division GO:0051785 Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. GOC:ai Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0051952 regulation of amine transport GO:0051952 Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of amine transport down-regulation of amine transport downregulation of amine transport inhibition of amine transport biological_process GO:0051953 negative regulation of amine transport GO:0051953 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. up regulation of amine transport up-regulation of amine transport upregulation of amine transport activation of amine transport stimulation of amine transport biological_process GO:0051954 positive regulation of amine transport GO:0051954 Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. biological_process GO:0051955 regulation of amino acid transport GO:0051955 Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. down regulation of amino acid transport down-regulation of amino acid transport downregulation of amino acid transport negative regulation of amino acid transmembrane transport inhibition of amino acid transport biological_process GO:0051956 negative regulation of amino acid transport GO:0051956 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai negative regulation of amino acid transmembrane transport GOC:mah Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. positive regulation of amino acid transmembrane transport up regulation of amino acid transport up-regulation of amino acid transport upregulation of amino acid transport activation of amino acid transport stimulation of amino acid transport biological_process GO:0051957 positive regulation of amino acid transport GO:0051957 Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:ai positive regulation of amino acid transmembrane transport GOC:mah The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. nucleobase, nucleoside and nucleotide metabolism biological_process nucleobase, nucleoside and nucleotide metabolic process GO:0055086 nucleobase-containing small molecule metabolic process GO:0055086 The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. GOC:vw Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. biological_process GO:0060255 regulation of macromolecule metabolic process GO:0060255 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GOC:dph GOC:tb Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. biological_process GO:0060284 regulation of cell development GO:0060284 Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. regulation of cellular localisation biological_process GO:0060341 regulation of cellular localization GO:0060341 Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. GOC:dph GOC:tb regulation of cellular localisation GOC:mah The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. dph 2009-04-28T08:42:53Z differential growth biological_process GO:0060560 developmental growth involved in morphogenesis GO:0060560 The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. GOC:dph differential growth GOC:dph A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. jl 2010-02-08T02:43:11Z GO:0016044 GO:0044802 cellular membrane organisation cellular membrane organization membrane organisation biological_process membrane organization and biogenesis single-organism membrane organization GO:0061024 membrane organization GO:0061024 A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. GOC:dph GOC:tb membrane organisation GOC:mah membrane organization and biogenesis GOC:mah Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. dph 2014-11-06T13:15:27Z E2 small conjugating protein conjugating enzyme activity molecular_function GO:0061650 ubiquitin-like protein conjugating enzyme activity GO:0061650 Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. GOC:dph small conjugating protein conjugating enzyme activity GOC:dph Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. dph 2014-11-06T13:17:36Z E2 molecular_function GO:0061651 Atg12 conjugating enzyme activity GO:0061651 Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. GOC:dph E2 GOC:dph Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. dph 2014-11-06T13:46:23Z small conjugating protein ligase activity molecular_function E3 GO:0061659 ubiquitin-like protein ligase activity GO:0061659 Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. GOC:dph small conjugating protein ligase activity GOC:dph E3 GOC:dph Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. dph 2014-11-06T13:50:42Z E3 molecular_function GO:0061660 Atg12 ligase activity GO:0061660 Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. GOC:dph E3 GOC:dph A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). dph 2015-05-06T11:22:38Z cellular_component GO:0061695 transferase complex, transferring phosphorus-containing groups GO:0061695 A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GOC:bhm GOC:dph The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. dph 2015-09-14T14:10:24Z biological_process GO:0061736 engulfment of target by autophagosome GO:0061736 The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. GOC:PARL GOC:autophagy GOC:dph GOC:pad A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. dph 2017-07-13T19:42:14Z biological_process GO:0061919 process utilizing autophagic mechanism GO:0061919 A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. PMID:21997368 PMID:22966490 PMID:28596378 The directed movement of a protein to a specific location in a plasma membrane. dph 2017-10-26T12:55:15Z biological_process GO:0061951 establishment of protein localization to plasma membrane GO:0061951 The directed movement of a protein to a specific location in a plasma membrane. GOC:dph GOC:vw A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. dph 2018-02-14T22:27:20Z first meiotic cell division biological_process GO:0061982 meiosis I cell cycle process GO:0061982 A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. PMID:29385397 first meiotic cell division PMID:29385397 A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. dph 2018-02-14T22:37:44Z second meiotic division biological_process GO:0061983 meiosis II cell cycle process GO:0061983 A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. PMID:29385397 second meiotic division PMID:29385397 Any process that modulates the rate, frequency or extent of a small molecule metabolic process. dph 2018-03-19T14:11:54Z regulation of small molecule metabolism biological_process GO:0062012 regulation of small molecule metabolic process GO:0062012 Any process that modulates the rate, frequency or extent of a small molecule metabolic process. GOC:vw Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. dph 2018-03-19T14:25:10Z positive regulation of small molecule metabolism biological_process GO:0062013 positive regulation of small molecule metabolic process GO:0062013 Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. GOC:vw Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. dph 2018-03-19T14:27:23Z negative regulation of small molecule metabolism biological_process GO:0062014 negative regulation of small molecule metabolic process GO:0062014 Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. GOC:vw The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. https://github.com/geneontology/go-ontology/issues/22580 GO:0006461 GO:0034622 GO:0043623 cellular protein complex assembly biological_process cellular macromolecule complex assembly cellular protein-containing complex assembly chaperone activity macromolecular complex assembly macromolecule complex assembly protein complex assembly protein complex formation GO:0065003 protein-containing complex assembly GO:0065003 The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. GOC:jl Any process that modulates a measurable attribute of any biological process, quality or function. regulation biological_process GO:0065007 biological regulation GO:0065007 Any process that modulates a measurable attribute of any biological process, quality or function. GOC:dph GOC:isa_complete GOC:mah GOC:pr GOC:vw Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. regulation of a molecular function biological_process GO:0065009 regulation of molecular function GO:0065009 Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GOC:isa_complete Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. extracellular membrane-enclosed organelle cellular_component GO:0065010 extracellular membrane-bounded organelle GO:0065010 Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. GOC:isa_complete Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. regulation of establishment of protein localisation biological_process GO:0070201 regulation of establishment of protein localization GO:0070201 Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. GOC:BHF GOC:mah regulation of establishment of protein localisation GOC:mah OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. https://github.com/geneontology/go-ontology/issues/24680 necrosis cellular necrosis biological_process GO:0070265 The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype. obsolete necrotic cell death true GO:0070265 OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. GOC:mtg_apoptosis PMID:18846107 PMID:20823910 necrosis GOC:mah cellular necrosis GOC:add Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. mah 2009-06-16T04:08:29Z cellular macromolecule localisation biological_process GO:0070727 cellular macromolecule localization GO:0070727 Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GOC:mah cellular macromolecule localisation GOC:mah The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. mah 2009-09-15T03:00:51Z biological_process GO:0070925 organelle assembly GO:0070925 The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GOC:mah A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. mah 2010-01-13T03:19:38Z GO:0070882 cell wall organisation or biogenesis cell wall organization or biogenesis at cellular level cellular cell wall organisation or biogenesis cellular cell wall organization or biogenesis biological_process GO:0071554 cell wall organization or biogenesis GO:0071554 A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. GOC:mah cell wall organisation or biogenesis GOC:mah cell wall organization or biogenesis at cellular level GOC:mah cellular cell wall organisation or biogenesis GOC:mah A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. mah 2010-01-13T03:33:07Z GO:0007047 GO:0044234 cell wall organisation cell wall organisation in other organism cell wall organization at cellular level cell wall organization in other organism cellular cell wall organisation cellular cell wall organization biological_process cell wall organization and biogenesis GO:0071555 cell wall organization GO:0071555 A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GOC:mah cell wall organisation in other organism GOC:mah cell wall organization at cellular level GOC:mah cell wall organization and biogenesis GOC:mah Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. mah 2010-02-25T04:00:13Z protein localisation in extracellular region protein localization in extracellular region biological_process GO:0071692 protein localization to extracellular region GO:0071692 Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. GOC:mah protein localisation in extracellular region GOC:mah The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. mah 2010-03-08T02:15:14Z biological_process GO:0071702 organic substance transport GO:0071702 The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. GOC:mah The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process organic molecular entity metabolism organic substance metabolism biological_process GO:0071704 organic substance metabolic process GO:0071704 The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. GOC:mah The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. mah 2010-03-08T03:56:28Z biological_process GO:0071705 nitrogen compound transport GO:0071705 The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:mah The aggregation, arrangement and bonding together of a set of components to form a membrane. mah 2010-03-10T11:19:17Z biological_process GO:0071709 membrane assembly GO:0071709 The aggregation, arrangement and bonding together of a set of components to form a membrane. GOC:mah A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. mah 2010-03-29T03:59:35Z nuclear membrane organisation biological_process nuclear membrane organization and biogenesis GO:0071763 nuclear membrane organization GO:0071763 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. GOC:mah nuclear membrane organisation GOC:mah nuclear membrane organization and biogenesis GOC:mah Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. https://github.com/geneontology/go-ontology/issues/25143 mah 2010-09-08T10:10:35Z RNA-protein complex subunit organization protein-RNA complex subunit organization ribonucleoprotein complex subunit organisation ribonucleoprotein complex subunit organization biological_process GO:0071826 protein-RNA complex organization GO:0071826 Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. GOC:mah RNA-protein complex subunit organization GOC:mah protein-RNA complex subunit organization GOC:mah ribonucleoprotein complex subunit organisation GOC:mah A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. https://github.com/geneontology/go-ontology/issues/27189 mah 2010-09-10T01:39:16Z GO:0071841 cellular component organisation or biogenesis cellular component organisation or biogenesis at cellular level cellular component organization or biogenesis at cellular level biological_process GO:0071840 Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. cellular component organization or biogenesis GO:0071840 A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. GOC:mah cellular component organisation or biogenesis GOC:mah cellular component organisation or biogenesis at cellular level GOC:mah The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component GO:0071944 cell periphery GO:0071944 The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. mah 2011-02-11T10:50:06Z ROS metabolic process reactive oxygen species metabolism biological_process GO:0072593 reactive oxygen species metabolic process GO:0072593 The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. GOC:mah ROS metabolic process CHEBI:26523 GOC:mah reactive oxygen species metabolism GOC:mah The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. mah 2011-02-14T01:56:51Z establishment of protein localisation to organelle biological_process GO:0072594 establishment of protein localization to organelle GO:0072594 The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. GOC:mah establishment of protein localisation to organelle GOC:mah A process in which a protein is transported to, or maintained in, a specific location in a membrane. mah 2011-02-14T02:35:18Z protein localisation in membrane protein localization in membrane biological_process GO:0072657 protein localization to membrane GO:0072657 A process in which a protein is transported to, or maintained in, a specific location in a membrane. GOC:mah protein localisation in membrane GOC:mah A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. tb 2009-07-10T10:29:23Z GO:0072661 GO:0090002 biological_process protein localisation in plasma membrane protein localization in plasma membrane protein targeting to plasma membrane protein-plasma membrane targeting GO:0072659 protein localization to plasma membrane GO:0072659 A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. GOC:mah protein localisation in plasma membrane GOC:mah protein-plasma membrane targeting GOC:mah A process in which a protein is transported to, or maintained at, a location in a vacuole. mah 2011-02-14T02:55:35Z protein localisation to vacuole biological_process GO:0072665 protein localization to vacuole GO:0072665 A process in which a protein is transported to, or maintained at, a location in a vacuole. GOC:ecd protein localisation to vacuole GOC:mah The directed movement of a protein to a specific location in a vacuole. mah 2011-02-14T02:56:29Z establishment of protein localisation to vacuole biological_process GO:0072666 establishment of protein localization to vacuole GO:0072666 The directed movement of a protein to a specific location in a vacuole. GOC:mah establishment of protein localisation to vacuole GOC:mah A process in which a protein is transported to, or maintained in, the cell cortex. mah 2012-04-11T01:16:33Z protein localisation to cell cortex biological_process GO:0072697 protein localization to cell cortex GO:0072697 A process in which a protein is transported to, or maintained in, the cell cortex. GOC:mah protein localisation to cell cortex GOC:mah Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. germ tube formation on or near host biological_process GO:0075009 germ tube formation GO:0075009 Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:pamgo_curators The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. https://github.com/geneontology/go-ontology/issues/19014 https://github.com/geneontology/go-ontology/issues/20472 formation of host infection structure biological_process formation by symbiont of infection structure on or near host formation of host penetration structure formation of infection structure on or near host GO:0075015 Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process. formation of infection structure GO:0075015 The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:pamgo_curators GO:0075052 true The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. https://github.com/geneontology/go-ontology/issues/18557 GO:0075057 initiation of symbiont penetration peg symbiont penetration peg initiation biological_process formation of symbiont penetration peg for entry into host symbiont penetration peg formation for entry into host GO:0075053 Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process. penetration peg formation GO:0075053 The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GOC:pamgo_curators PMID:26441323 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. dhl 2009-04-22T04:30:52Z biological_process GO:0080090 regulation of primary metabolic process GO:0080090 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. PMID:19211694 A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. An interaction between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other. jl 2010-07-27T01:25:21Z biological_process mutualism GO:0085030 mutualism symbiotic process benefiting host GO:0085030 A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. GOC:pdt Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. tb 2009-09-09T11:39:52Z biological_process GO:0090068 positive regulation of cell cycle process GO:0090068 Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GOC:dph GOC:tb Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. tb 2009-10-23T11:21:38Z biological_process GO:0090087 regulation of peptide transport GO:0090087 Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GOC:dph GOC:tb The directed movement of a protein to a specific location in a membrane. tb 2009-12-08T03:18:51Z establishment of protein localisation in membrane establishment of protein localization in membrane biological_process GO:0090150 establishment of protein localization to membrane GO:0090150 The directed movement of a protein to a specific location in a membrane. GOC:ascb_2009 GOC:dph GOC:tb establishment of protein localisation in membrane GOC:mah Any cellular metabolic process involving nucleic acids. https://github.com/geneontology/go-ontology/issues/26133 tb 2010-04-07T10:18:47Z biological_process GO:0090304 nucleic acid metabolic process GO:0090304 Any cellular metabolic process involving nucleic acids. GOC:dph GOC:tb Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. tb 2010-04-16T03:45:07Z biological_process GO:0090316 positive regulation of intracellular protein transport GO:0090316 Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. GOC:tb Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. tb 2010-04-16T03:45:07Z biological_process GO:0090317 negative regulation of intracellular protein transport GO:0090317 Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. GOC:tb A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. tb 2012-07-30T01:50:41Z protein localization in nuclear envelope biological_process GO:0090435 protein localization to nuclear envelope GO:0090435 A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. GOC:tb A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. tb 2016-07-19T17:00:49Z RNA localisation to nucleus biological_process GO:0090685 RNA localization to nucleus GO:0090685 A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. GOC:mah PMID:26305931 RNA localisation to nucleus GOC:mah Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. pr 2011-09-23T02:31:01Z molecular_function GO:0097159 organic cyclic compound binding GO:0097159 Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. GOC:sjw PMID:7583672 The chemical reactions and pathways involving the ammonium ion. pr 2011-09-28T04:21:30Z ammonium ion metabolism biological_process ammonium metabolic process GO:0097164 ammonium ion metabolic process GO:0097164 The chemical reactions and pathways involving the ammonium ion. GOC:dhl GOC:tb PMID:14671018 The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. pr 2011-10-10T11:29:49Z epoxide metabolism biological_process GO:0097176 epoxide metabolic process GO:0097176 The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. GOC:rs PMID:15822179 Binding to a carbohydrate derivative. pr 2012-08-02T13:03:39Z molecular_function GO:0097367 carbohydrate derivative binding GO:0097367 Binding to a carbohydrate derivative. GOC:pr Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. https://github.com/geneontology/go-ontology/issues/22173 dos 2013-11-11T12:59:11Z GO:0009814 defence response incompatible interaction defence response to pathogen, incompatible interaction defense response, incompatible interaction resistance response to pathogen biological_process GO:0098542 defense response to other organism GO:0098542 Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. GOC:dos A membrane that is a (regional) part of the plasma membrane. dos 2014-03-06T11:55:32Z region of plasma membrane cellular_component GO:0098590 Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. plasma membrane region GO:0098590 A membrane that is a (regional) part of the plasma membrane. GOC:dos The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. uptake biological_process GO:0098657 import into cell GO:0098657 The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. GOC:dos One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. biological_process GO:0098762 This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). meiotic cell cycle phase GO:0098762 One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. GOC:dos A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. biological_process GO:0098764 Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). meiosis I cell cycle phase GO:0098764 A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. GOC:dos Any protein complex that is part of a membrane. cellular_component GO:0098796 membrane protein complex GO:0098796 Any protein complex that is part of a membrane. GOC:dos Any protein complex that is part of the plasma membrane. cellular_component GO:0098797 plasma membrane protein complex GO:0098797 Any protein complex that is part of the plasma membrane. GOC:dos Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. cellular_component GO:0099568 cytoplasmic region GO:0099568 Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. GOC:dos A process in which protein is transported from one region of the plasma membrane to another. biological_process GO:0099632 protein transport within plasma membrane GO:0099632 A process in which protein is transported from one region of the plasma membrane to another. GOC:dos The complete extent of cell cortex that underlies some some region of the plasma membrane. perimembrane region cellular_component GO:0099738 cell cortex region GO:0099738 The complete extent of cell cortex that underlies some some region of the plasma membrane. GOC:dos The process in which a nuclear membrane is synthesized, aggregates, and bonds together. biological_process GO:0101025 nuclear membrane biogenesis GO:0101025 The process in which a nuclear membrane is synthesized, aggregates, and bonds together. GOC:vw The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. hjd 2018-04-16T19:06:06Z DON biosynthetic process deoxynivalenol biosynthetic process vomitoxin anabolism vomitoxin biosynthesis vomitoxin formation vomitoxin synthesis biological_process GO:0106110 vomitoxin biosynthetic process GO:0106110 The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. PMID:19333439 PMID:25680507 PMID:25758923 PMID:8637056 https://doi.org/10.1007/BF03356188 The directional movement of a symbiont from one host cell to another. https://github.com/geneontology/go-ontology/issues/27786 hjd 2020-05-01T14:09:35Z cell-to-cell migration in host symbiont-mediated dissemination across host cells biological_process GO:0106259 symbiont-mediated cell-to-cell migration in host GO:0106259 The directional movement of a symbiont from one host cell to another. GOC:vw PMID:18456802 PMID:19262673 PMID:19816653 PMID:29567712 A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component GO:0110165 cellular anatomical entity GO:0110165 A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. GOC:kmv The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). https://github.com/geneontology/go-ontology/issues/19936 krc 2020-09-02T23:13:44Z alkene substituted compound metabolic process alkene substituted compound metabolism biological_process GO:0120254 olefinic compound metabolic process GO:0120254 The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). GOC:krc The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). https://github.com/geneontology/go-ontology/issues/19936 krc 2020-09-02T23:30:20Z alkene substituted compound anabolic process alkene substituted compound anabolism alkene substituted compound biosynthesis alkene substituted compound biosynthetic process alkene substituted compound synthesis biological_process GO:0120255 olefinic compound biosynthetic process GO:0120255 The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). GOC:krc alkene substituted compound anabolic process GOC:krc alkene substituted compound anabolism GOC:krc alkene substituted compound biosynthesis GOC:krc alkene substituted compound biosynthetic process GOC:krc alkene substituted compound synthesis GOC:krc One of the two nuclear divisions that occur as part of the meiotic cell cycle. https://github.com/geneontology/go-ontology/issues/19910 pg 2017-03-23T09:40:00Z meiosis biological_process GO:0140013 meiotic nuclear division GO:0140013 One of the two nuclear divisions that occur as part of the meiotic cell cycle. PMID:9334324 Catalytic activity that acts to modify a protein. https://github.com/geneontology/go-ontology/issues/14225 pg 2017-09-14T10:32:59Z molecular_function GO:0140096 catalytic activity, acting on a protein GO:0140096 Catalytic activity that acts to modify a protein. GOC:molecular_function_refactoring GOC:pdt Catalytic activity that acts to modify RNA, driven by ATP hydrolysis. https://github.com/geneontology/go-ontology/issues/14225 https://github.com/geneontology/go-ontology/issues/21612 pg 2017-09-14T12:05:21Z molecular_function GO:0140098 catalytic activity, acting on RNA GO:0140098 Catalytic activity that acts to modify RNA, driven by ATP hydrolysis. GOC:molecular_function_refactoring GOC:pdt Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein. pg 2018-10-01T10:03:21Z molecular_function GO:0140272 Note that as GO captures normal processes, it may be that exogenous proteins interactions are normal for one of the participating species but not the other. Therefore reciprocal annotations should not be made without confirming that it is physiological relevant. exogenous protein binding GO:0140272 Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein. PMID:28861068 The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. pg 2019-05-22T11:20:45Z efflux biological_process GO:0140352 export from cell GO:0140352 The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. GOC:pg A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. pg 2020-09-09T05:12:38Z nuclear complex cellular_component GO:0140513 nuclear protein-containing complex GO:0140513 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. GOC:pg Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. https://github.com/geneontology/go-ontology/issues/20261 pg 2020-11-11T17:19:06Z biological_process GO:0140546 defense response to symbiont GO:0140546 Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. GOC:pg The division of a vacuole within a cell to form two or more separate vacuoles. https://github.com/geneontology/go-ontology/issues/20639 pg 2021-01-04T10:17:58Z biological_process GO:0140572 vacuole fission GO:0140572 The division of a vacuole within a cell to form two or more separate vacuoles. PMID:19643199 Catalytic activity that acts to modify a nucleic acid. https://github.com/geneontology/go-ontology/issues/21402 pg 2021-05-11T06:31:07Z molecular_function GO:0140640 catalytic activity, acting on a nucleic acid GO:0140640 Catalytic activity that acts to modify a nucleic acid. GOC:pg A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. https://github.com/geneontology/go-ontology/issues/21612 https://github.com/geneontology/go-ontology/issues/22371 pg 2021-06-15T07:35:06Z ATP hydrolysis-dependent activity ATPase activity ATPase activity, coupled ATPase-dependent activity molecular_function GO:0140657 Note that this term represents a grouping class that includes all proteins that use ATP hydrolysis to drive a reaction; it is not meant to capture the ATP hydrolysis reaction itself. To annotate ATP hydrolysis, please use 'ATP hydrolysis activity ; GO:0016887'. ATP-dependent activity GO:0140657 A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. PMID:24878343 PMID:25750732 PMID:32933017 PMID:33818025 PMID:33873056 PMID:33988324 The chemical reactions and pathways involving an L-amino acid. https://github.com/geneontology/go-ontology/issues/23268 ew 2023-11-20T23:41:23Z L-alpha-amino acid metabolism L-amino acid metabolism biological_process GO:0170033 L-amino acid metabolic process GO:0170033 The chemical reactions and pathways involving an L-amino acid. GOC:edw The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. https://github.com/geneontology/go-ontology/issues/23268 ew 2023-11-20T23:42:06Z L-amino acid anabolism L-amino acid biosynthesis L-amino acid formation L-amino acid synthesis biological_process GO:0170034 L-amino acid biosynthetic process GO:0170034 The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. GOC:edw The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. https://github.com/geneontology/go-ontology/issues/23268 ew 2023-12-18T16:28:19Z proteinogenic amino acid anabolism proteinogenic amino acid biosynthesis proteinogenic amino acid formation proteinogenic amino acid synthesis biological_process GO:0170038 proteinogenic amino acid biosynthetic process GO:0170038 The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. GOC:ew The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. https://github.com/geneontology/go-ontology/issues/23268 ew 2023-12-18T17:31:08Z proteinogenic amino acid metabolism biological_process GO:0170039 proteinogenic amino acid metabolic process GO:0170039 The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. GOC:ew Any process that modulates the frequency, rate or extent of protein localization to nucleus. bf 2012-03-12T01:23:44Z regulation of protein localisation to nucleus regulation of protein localization in cell nucleus regulation of protein localization in nucleus biological_process GO:1900180 regulation of protein localization to nucleus GO:1900180 Any process that modulates the frequency, rate or extent of protein localization to nucleus. GOC:TermGenie regulation of protein localisation to nucleus GOC:TermGenie regulation of protein localization in cell nucleus GOC:TermGenie regulation of protein localization in nucleus GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. bf 2012-03-12T01:23:48Z down regulation of protein localisation to nucleus down regulation of protein localization in cell nucleus down regulation of protein localization in nucleus down regulation of protein localization to nucleus down-regulation of protein localisation to nucleus down-regulation of protein localization in cell nucleus down-regulation of protein localization in nucleus down-regulation of protein localization to nucleus downregulation of protein localisation to nucleus downregulation of protein localization in cell nucleus downregulation of protein localization in nucleus downregulation of protein localization to nucleus negative regulation of protein localisation to nucleus negative regulation of protein localization in cell nucleus negative regulation of protein localization in nucleus inhibition of protein localisation to nucleus inhibition of protein localization in cell nucleus inhibition of protein localization in nucleus inhibition of protein localization to nucleus biological_process GO:1900181 negative regulation of protein localization to nucleus GO:1900181 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. GOC:TermGenie down regulation of protein localisation to nucleus GOC:TermGenie down regulation of protein localization in cell nucleus GOC:TermGenie down regulation of protein localization in nucleus GOC:TermGenie down regulation of protein localization to nucleus GOC:TermGenie down-regulation of protein localisation to nucleus GOC:TermGenie down-regulation of protein localization in cell nucleus GOC:TermGenie down-regulation of protein localization in nucleus GOC:TermGenie down-regulation of protein localization to nucleus GOC:TermGenie downregulation of protein localisation to nucleus GOC:TermGenie downregulation of protein localization in cell nucleus GOC:TermGenie downregulation of protein localization in nucleus GOC:TermGenie downregulation of protein localization to nucleus GOC:TermGenie negative regulation of protein localisation to nucleus GOC:TermGenie negative regulation of protein localization in cell nucleus GOC:TermGenie negative regulation of protein localization in nucleus GOC:TermGenie inhibition of protein localisation to nucleus GOC:TermGenie inhibition of protein localization in cell nucleus GOC:TermGenie inhibition of protein localization in nucleus GOC:TermGenie inhibition of protein localization to nucleus GOC:TermGenie Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. bf 2012-03-12T01:23:52Z activation of protein localization in nucleus positive regulation of protein localisation to nucleus positive regulation of protein localization in cell nucleus positive regulation of protein localization in nucleus up regulation of protein localisation to nucleus up regulation of protein localization in cell nucleus up regulation of protein localization in nucleus up regulation of protein localization to nucleus up-regulation of protein localisation to nucleus up-regulation of protein localization in cell nucleus up-regulation of protein localization in nucleus up-regulation of protein localization to nucleus upregulation of protein localisation to nucleus upregulation of protein localization in cell nucleus upregulation of protein localization in nucleus upregulation of protein localization to nucleus activation of protein localisation to nucleus activation of protein localization in cell nucleus activation of protein localization to nucleus biological_process GO:1900182 positive regulation of protein localization to nucleus GO:1900182 Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. GOC:TermGenie activation of protein localization in nucleus GOC:TermGenie positive regulation of protein localisation to nucleus GOC:TermGenie positive regulation of protein localization in cell nucleus GOC:TermGenie positive regulation of protein localization in nucleus GOC:TermGenie up regulation of protein localisation to nucleus GOC:TermGenie up regulation of protein localization in cell nucleus GOC:TermGenie up regulation of protein localization in nucleus GOC:TermGenie up regulation of protein localization to nucleus GOC:TermGenie up-regulation of protein localisation to nucleus GOC:TermGenie up-regulation of protein localization in cell nucleus GOC:TermGenie up-regulation of protein localization in nucleus GOC:TermGenie up-regulation of protein localization to nucleus GOC:TermGenie upregulation of protein localisation to nucleus GOC:TermGenie upregulation of protein localization in cell nucleus GOC:TermGenie upregulation of protein localization in nucleus GOC:TermGenie upregulation of protein localization to nucleus GOC:TermGenie activation of protein localisation to nucleus GOC:TermGenie activation of protein localization in cell nucleus GOC:TermGenie activation of protein localization to nucleus GOC:TermGenie Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. ss 2012-07-25T02:26:58Z regulation of translation initiation ternary complex assembly biological_process GO:1901190 regulation of formation of translation initiation ternary complex GO:1901190 Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. GOC:TermGenie regulation of translation initiation ternary complex assembly GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. ss 2012-07-25T02:27:21Z down regulation of formation of translation initiation ternary complex down regulation of translation initiation ternary complex assembly down-regulation of formation of translation initiation ternary complex down-regulation of translation initiation ternary complex assembly downregulation of formation of translation initiation ternary complex downregulation of translation initiation ternary complex assembly inhibition of translation initiation ternary complex assembly negative regulation of translation initiation ternary complex assembly inhibition of formation of translation initiation ternary complex biological_process GO:1901191 negative regulation of formation of translation initiation ternary complex GO:1901191 Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. GOC:TermGenie down regulation of formation of translation initiation ternary complex GOC:TermGenie down regulation of translation initiation ternary complex assembly GOC:TermGenie down-regulation of formation of translation initiation ternary complex GOC:TermGenie down-regulation of translation initiation ternary complex assembly GOC:TermGenie downregulation of formation of translation initiation ternary complex GOC:TermGenie downregulation of translation initiation ternary complex assembly GOC:TermGenie inhibition of translation initiation ternary complex assembly GOC:TermGenie negative regulation of translation initiation ternary complex assembly GOC:TermGenie inhibition of formation of translation initiation ternary complex GOC:TermGenie Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. ss 2012-07-25T02:27:29Z activation of translation initiation ternary complex assembly positive regulation of translation initiation ternary complex assembly up regulation of formation of translation initiation ternary complex up regulation of translation initiation ternary complex assembly up-regulation of formation of translation initiation ternary complex up-regulation of translation initiation ternary complex assembly upregulation of formation of translation initiation ternary complex upregulation of translation initiation ternary complex assembly activation of formation of translation initiation ternary complex biological_process GO:1901192 positive regulation of formation of translation initiation ternary complex GO:1901192 Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. GOC:TermGenie activation of translation initiation ternary complex assembly GOC:TermGenie positive regulation of translation initiation ternary complex assembly GOC:TermGenie up regulation of formation of translation initiation ternary complex GOC:TermGenie up regulation of translation initiation ternary complex assembly GOC:TermGenie up-regulation of formation of translation initiation ternary complex GOC:TermGenie up-regulation of translation initiation ternary complex assembly GOC:TermGenie upregulation of formation of translation initiation ternary complex GOC:TermGenie upregulation of translation initiation ternary complex assembly GOC:TermGenie activation of formation of translation initiation ternary complex GOC:TermGenie The chemical reactions and pathways involving organic cyclic compound. bf 2012-09-14T09:03:51Z organic cyclic compound metabolism biological_process GO:1901360 organic cyclic compound metabolic process GO:1901360 The chemical reactions and pathways involving organic cyclic compound. GOC:TermGenie organic cyclic compound metabolism GOC:TermGenie The chemical reactions and pathways resulting in the formation of organic cyclic compound. bf 2012-09-14T09:05:22Z organic cyclic compound anabolism organic cyclic compound biosynthesis organic cyclic compound formation organic cyclic compound synthesis biological_process GO:1901362 organic cyclic compound biosynthetic process GO:1901362 The chemical reactions and pathways resulting in the formation of organic cyclic compound. GOC:TermGenie organic cyclic compound anabolism GOC:TermGenie organic cyclic compound biosynthesis GOC:TermGenie organic cyclic compound formation GOC:TermGenie organic cyclic compound synthesis GOC:TermGenie The chemical reactions and pathways resulting in the formation of ether. pr 2012-10-17T09:42:47Z ether anabolism ether biosynthesis ether formation ether synthesis biological_process GO:1901503 ether biosynthetic process GO:1901503 The chemical reactions and pathways resulting in the formation of ether. GOC:TermGenie GOC:pr ether anabolism GOC:TermGenie ether biosynthesis GOC:TermGenie ether formation GOC:TermGenie ether synthesis GOC:TermGenie The chemical reactions and pathways involving organonitrogen compound. https://github.com/geneontology/go-ontology/issues/26424 pr 2012-11-04T15:17:52Z organonitrogen compound metabolism biological_process GO:1901564 organonitrogen compound metabolic process GO:1901564 The chemical reactions and pathways involving organonitrogen compound. GOC:TermGenie GOC:pr organonitrogen compound metabolism GOC:TermGenie The chemical reactions and pathways resulting in the formation of organonitrogen compound. https://github.com/geneontology/go-ontology/issues/26424 pr 2012-11-04T15:18:00Z organonitrogen compound anabolism organonitrogen compound biosynthesis organonitrogen compound formation organonitrogen compound synthesis biological_process GO:1901566 organonitrogen compound biosynthetic process GO:1901566 The chemical reactions and pathways resulting in the formation of organonitrogen compound. GOC:TermGenie GOC:pr organonitrogen compound anabolism GOC:TermGenie organonitrogen compound biosynthesis GOC:TermGenie organonitrogen compound formation GOC:TermGenie organonitrogen compound synthesis GOC:TermGenie The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. pr 2012-11-05T11:04:40Z organic molecular entity anabolism organic molecular entity biosynthesis organic molecular entity biosynthetic process organic molecular entity formation organic molecular entity synthesis organic substance anabolism organic substance biosynthesis organic substance formation organic substance synthesis biological_process GO:1901576 organic substance biosynthetic process GO:1901576 The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. GOC:TermGenie GOC:pr organic molecular entity anabolism GOC:TermGenie organic molecular entity biosynthesis GOC:TermGenie organic molecular entity formation GOC:TermGenie organic molecular entity synthesis GOC:TermGenie The chemical reactions and pathways involving an alpha-amino acid. tb 2012-11-08T17:39:50Z alpha-amino acid metabolism biological_process GO:1901605 alpha-amino acid metabolic process GO:1901605 The chemical reactions and pathways involving an alpha-amino acid. GOC:TermGenie alpha-amino acid metabolism GOC:TermGenie The chemical reactions and pathways resulting in the formation of an alpha-amino acid. tb 2012-11-08T17:39:58Z alpha-amino acid anabolism alpha-amino acid biosynthesis alpha-amino acid formation alpha-amino acid synthesis biological_process GO:1901607 alpha-amino acid biosynthetic process GO:1901607 The chemical reactions and pathways resulting in the formation of an alpha-amino acid. GOC:TermGenie alpha-amino acid anabolism GOC:TermGenie alpha-amino acid biosynthesis GOC:TermGenie alpha-amino acid formation GOC:TermGenie alpha-amino acid synthesis GOC:TermGenie The chemical reactions and pathways involving organic hydroxy compound. pr 2012-11-13T12:54:27Z organic hydroxy compound metabolism biological_process GO:1901615 organic hydroxy compound metabolic process GO:1901615 The chemical reactions and pathways involving organic hydroxy compound. GOC:TermGenie GOC:pr organic hydroxy compound metabolism GOC:TermGenie The chemical reactions and pathways resulting in the formation of organic hydroxy compound. pr 2012-11-13T12:54:36Z organic hydroxy compound anabolism organic hydroxy compound biosynthesis organic hydroxy compound formation organic hydroxy compound synthesis biological_process GO:1901617 organic hydroxy compound biosynthetic process GO:1901617 The chemical reactions and pathways resulting in the formation of organic hydroxy compound. GOC:TermGenie GOC:pr organic hydroxy compound anabolism GOC:TermGenie organic hydroxy compound biosynthesis GOC:TermGenie organic hydroxy compound formation GOC:TermGenie organic hydroxy compound synthesis GOC:TermGenie Any process that modulates the frequency, rate or extent of organelle assembly. pr 2013-05-14T09:43:21Z biological_process GO:1902115 regulation of organelle assembly GO:1902115 Any process that modulates the frequency, rate or extent of organelle assembly. GOC:TermGenie GOC:pr Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. pr 2013-05-14T09:43:31Z down regulation of organelle assembly down-regulation of organelle assembly downregulation of organelle assembly inhibition of organelle assembly biological_process GO:1902116 negative regulation of organelle assembly GO:1902116 Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. GOC:TermGenie GOC:pr down regulation of organelle assembly GOC:TermGenie down-regulation of organelle assembly GOC:TermGenie downregulation of organelle assembly GOC:TermGenie inhibition of organelle assembly GOC:TermGenie Any process that activates or increases the frequency, rate or extent of organelle assembly. pr 2013-05-14T09:43:36Z up regulation of organelle assembly up-regulation of organelle assembly upregulation of organelle assembly activation of organelle assembly biological_process GO:1902117 positive regulation of organelle assembly GO:1902117 Any process that activates or increases the frequency, rate or extent of organelle assembly. GOC:TermGenie GOC:pr up regulation of organelle assembly GOC:TermGenie up-regulation of organelle assembly GOC:TermGenie upregulation of organelle assembly GOC:TermGenie activation of organelle assembly GOC:TermGenie A protein complex which is capable of catalytic activity. https://github.com/geneontology/go-ontology/issues/19980 bhm 2013-11-13T16:18:47Z enzyme complex cellular_component GO:1902494 catalytic complex GO:1902494 A protein complex which is capable of catalytic activity. GOC:TermGenie GOC:bhm PMID:8077207 enzyme complex GOC:bhm GOC:jl The chemical reactions and pathways involving secondary alcohol. tt 2014-01-22T10:14:52Z secondary alcohol metabolism biological_process GO:1902652 secondary alcohol metabolic process GO:1902652 The chemical reactions and pathways involving secondary alcohol. GOC:TermGenie GOC:mengo_curators GO_REF:0000068 PMID:11288200 secondary alcohol metabolism GOC:TermGenie The chemical reactions and pathways resulting in the formation of secondary alcohol. tt 2014-01-22T10:15:02Z secondary alcohol anabolism secondary alcohol biosynthesis secondary alcohol formation secondary alcohol synthesis biological_process GO:1902653 secondary alcohol biosynthetic process GO:1902653 The chemical reactions and pathways resulting in the formation of secondary alcohol. GOC:TermGenie GOC:mengo_curators GO_REF:0000068 PMID:11288200 secondary alcohol anabolism GOC:TermGenie secondary alcohol biosynthesis GOC:TermGenie secondary alcohol formation GOC:TermGenie secondary alcohol synthesis GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. jl 2014-02-05T16:32:01Z down regulation of RNA anabolism down regulation of RNA biosynthesis down regulation of RNA biosynthetic process down regulation of RNA formation down regulation of RNA synthesis down-regulation of RNA anabolism down-regulation of RNA biosynthesis down-regulation of RNA biosynthetic process down-regulation of RNA formation down-regulation of RNA synthesis downregulation of RNA anabolism downregulation of RNA biosynthesis downregulation of RNA biosynthetic process downregulation of RNA formation downregulation of RNA synthesis negative regulation of RNA anabolism negative regulation of RNA biosynthesis negative regulation of RNA formation negative regulation of RNA synthesis inhibition of RNA anabolism inhibition of RNA biosynthesis inhibition of RNA biosynthetic process inhibition of RNA formation inhibition of RNA synthesis biological_process GO:1902679 negative regulation of RNA biosynthetic process GO:1902679 Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. GO:jl GOC:TermGenie GO_REF:0000058 down regulation of RNA anabolism GOC:TermGenie down regulation of RNA biosynthesis GOC:TermGenie down regulation of RNA biosynthetic process GOC:TermGenie down regulation of RNA formation GOC:TermGenie down regulation of RNA synthesis GOC:TermGenie down-regulation of RNA anabolism GOC:TermGenie down-regulation of RNA biosynthesis GOC:TermGenie down-regulation of RNA biosynthetic process GOC:TermGenie down-regulation of RNA formation GOC:TermGenie down-regulation of RNA synthesis GOC:TermGenie downregulation of RNA anabolism GOC:TermGenie downregulation of RNA biosynthesis GOC:TermGenie downregulation of RNA biosynthetic process GOC:TermGenie downregulation of RNA formation GOC:TermGenie downregulation of RNA synthesis GOC:TermGenie negative regulation of RNA anabolism GOC:TermGenie negative regulation of RNA biosynthesis GOC:TermGenie negative regulation of RNA formation GOC:TermGenie negative regulation of RNA synthesis GOC:TermGenie inhibition of RNA anabolism GOC:TermGenie inhibition of RNA biosynthesis GOC:TermGenie inhibition of RNA biosynthetic process GOC:TermGenie inhibition of RNA formation GOC:TermGenie inhibition of RNA synthesis GOC:TermGenie Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. jl 2014-02-05T16:32:10Z positive regulation of RNA anabolism positive regulation of RNA biosynthesis positive regulation of RNA formation positive regulation of RNA synthesis up regulation of RNA anabolism up regulation of RNA biosynthesis up regulation of RNA biosynthetic process up regulation of RNA formation up regulation of RNA synthesis up-regulation of RNA anabolism up-regulation of RNA biosynthesis up-regulation of RNA biosynthetic process up-regulation of RNA formation up-regulation of RNA synthesis upregulation of RNA anabolism upregulation of RNA biosynthesis upregulation of RNA biosynthetic process upregulation of RNA formation upregulation of RNA synthesis activation of RNA anabolism activation of RNA biosynthesis activation of RNA biosynthetic process activation of RNA formation activation of RNA synthesis biological_process GO:1902680 positive regulation of RNA biosynthetic process GO:1902680 Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. GO:jl GOC:TermGenie GO_REF:0000058 positive regulation of RNA anabolism GOC:TermGenie positive regulation of RNA biosynthesis GOC:TermGenie positive regulation of RNA formation GOC:TermGenie positive regulation of RNA synthesis GOC:TermGenie up regulation of RNA anabolism GOC:TermGenie up regulation of RNA biosynthesis GOC:TermGenie up regulation of RNA biosynthetic process GOC:TermGenie up regulation of RNA formation GOC:TermGenie up regulation of RNA synthesis GOC:TermGenie up-regulation of RNA anabolism GOC:TermGenie up-regulation of RNA biosynthesis GOC:TermGenie up-regulation of RNA biosynthetic process GOC:TermGenie up-regulation of RNA formation GOC:TermGenie up-regulation of RNA synthesis GOC:TermGenie upregulation of RNA anabolism GOC:TermGenie upregulation of RNA biosynthesis GOC:TermGenie upregulation of RNA biosynthetic process GOC:TermGenie upregulation of RNA formation GOC:TermGenie upregulation of RNA synthesis GOC:TermGenie activation of RNA anabolism GOC:TermGenie activation of RNA biosynthesis GOC:TermGenie activation of RNA biosynthetic process GOC:TermGenie activation of RNA formation GOC:TermGenie activation of RNA synthesis GOC:TermGenie The disaggregation of an organelle into its constituent components. jl 2014-05-13T12:36:03Z organelle degradation biological_process GO:1903008 organelle disassembly GO:1903008 The disaggregation of an organelle into its constituent components. GOC:TermGenie GO_REF:0000079 A process that is part of the meiotic cell cycle. jl 2014-05-22T14:22:28Z biological_process GO:1903046 meiotic cell cycle process GO:1903046 A process that is part of the meiotic cell cycle. GOC:TermGenie GOC:mtg_cell_cycle GO_REF:0000060 Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. tb 2009-07-10T10:32:44Z GO:0090003 GO:1905963 regulation of protein localization in plasma membrane biological_process regulation of establishment of protein localisation in plasma membrane regulation of establishment of protein localization in plasma membrane regulation of establishment of protein localization to plasma membrane regulation of protein localisation in plasma membrane regulation of protein targeting to plasma membrane regulation of protein-plasma membrane targeting GO:1903076 regulation of protein localization to plasma membrane GO:1903076 Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. GOC:BHF GOC:TermGenie GOC:rl GO_REF:0000058 PMID:11602640 regulation of protein localization in plasma membrane GOC:TermGenie regulation of establishment of protein localisation in plasma membrane GOC:mah regulation of protein localisation in plasma membrane GOC:TermGenie regulation of protein-plasma membrane targeting GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. tb 2014-05-29T17:10:16Z GO:0090005 GO:1905964 down regulation of protein localisation in plasma membrane down regulation of protein localization in plasma membrane down regulation of protein localization to plasma membrane down-regulation of protein localisation in plasma membrane down-regulation of protein localization in plasma membrane down-regulation of protein localization to plasma membrane downregulation of protein localisation in plasma membrane downregulation of protein localization in plasma membrane downregulation of protein localization to plasma membrane negative regulation of protein localization in plasma membrane inhibition of protein localisation in plasma membrane inhibition of protein localization in plasma membrane inhibition of protein localization to plasma membrane inhibition of protein targeting to plasma membrane inhibition of protein-plasma membrane targeting biological_process down regulation of protein targeting to plasma membrane down regulation of protein-plasma membrane targeting down-regulation of protein targeting to plasma membrane down-regulation of protein-plasma membrane targeting downregulation of protein targeting to plasma membrane downregulation of protein-plasma membrane targeting negative regulation of establishment of protein localisation in plasma membrane negative regulation of establishment of protein localization in plasma membrane negative regulation of establishment of protein localization to plasma membrane negative regulation of protein localisation in plasma membrane negative regulation of protein targeting to plasma membrane negative regulation of protein-plasma membrane targeting GO:1903077 negative regulation of protein localization to plasma membrane GO:1903077 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. GOC:BHF GOC:TermGenie GOC:rl GO_REF:0000058 PMID:11602640 down regulation of protein localisation in plasma membrane GOC:TermGenie down regulation of protein localization in plasma membrane GOC:TermGenie down regulation of protein localization to plasma membrane GOC:TermGenie down-regulation of protein localisation in plasma membrane GOC:TermGenie down-regulation of protein localization in plasma membrane GOC:TermGenie down-regulation of protein localization to plasma membrane GOC:TermGenie downregulation of protein localisation in plasma membrane GOC:TermGenie downregulation of protein localization in plasma membrane GOC:TermGenie downregulation of protein localization to plasma membrane GOC:TermGenie negative regulation of protein localization in plasma membrane GOC:TermGenie inhibition of protein localisation in plasma membrane GOC:TermGenie inhibition of protein localization in plasma membrane GOC:TermGenie inhibition of protein localization to plasma membrane GOC:TermGenie inhibition of protein targeting to plasma membrane GOC:TermGenie inhibition of protein-plasma membrane targeting GOC:TermGenie down regulation of protein targeting to plasma membrane GOC:TermGenie down regulation of protein-plasma membrane targeting GOC:TermGenie down-regulation of protein targeting to plasma membrane GOC:TermGenie down-regulation of protein-plasma membrane targeting GOC:TermGenie downregulation of protein targeting to plasma membrane GOC:TermGenie downregulation of protein-plasma membrane targeting GOC:TermGenie negative regulation of establishment of protein localisation in plasma membrane GOC:mah negative regulation of protein localisation in plasma membrane GOC:TermGenie negative regulation of protein-plasma membrane targeting GOC:TermGenie Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. tb 2009-07-10T10:34:17Z GO:0090004 GO:1905965 positive regulation of protein localisation in plasma membrane positive regulation of protein localization in plasma membrane up regulation of protein localisation in plasma membrane up regulation of protein localization in plasma membrane up regulation of protein localization to plasma membrane up-regulation of protein localisation in plasma membrane up-regulation of protein localization in plasma membrane up-regulation of protein localization to plasma membrane upregulation of protein localisation in plasma membrane upregulation of protein localization in plasma membrane upregulation of protein localization to plasma membrane activation of protein localisation in plasma membrane activation of protein localization in plasma membrane activation of protein localization to plasma membrane activation of protein targeting to plasma membrane activation of protein-plasma membrane targeting biological_process positive regulation of establishment of protein localisation in plasma membrane positive regulation of establishment of protein localization to plasma membrane positive regulation of protein targeting to plasma membrane positive regulation of protein-plasma membrane targeting up regulation of protein targeting to plasma membrane up regulation of protein-plasma membrane targeting up-regulation of protein targeting to plasma membrane up-regulation of protein-plasma membrane targeting upregulation of protein targeting to plasma membrane upregulation of protein-plasma membrane targeting GO:1903078 positive regulation of protein localization to plasma membrane GO:1903078 Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. GOC:BHF GOC:TermGenie GOC:rl GO_REF:0000058 PMID:11602640 positive regulation of protein localisation in plasma membrane GOC:TermGenie positive regulation of protein localization in plasma membrane GOC:TermGenie up regulation of protein localisation in plasma membrane GOC:TermGenie up regulation of protein localization in plasma membrane GOC:TermGenie up regulation of protein localization to plasma membrane GOC:TermGenie up-regulation of protein localisation in plasma membrane GOC:TermGenie up-regulation of protein localization in plasma membrane GOC:TermGenie up-regulation of protein localization to plasma membrane GOC:TermGenie upregulation of protein localisation in plasma membrane GOC:TermGenie upregulation of protein localization in plasma membrane GOC:TermGenie upregulation of protein localization to plasma membrane GOC:TermGenie activation of protein localisation in plasma membrane GOC:TermGenie activation of protein localization in plasma membrane GOC:TermGenie activation of protein localization to plasma membrane GOC:TermGenie activation of protein targeting to plasma membrane GOC:TermGenie activation of protein-plasma membrane targeting GOC:TermGenie positive regulation of establishment of protein localisation in plasma membrane GOC:mah positive regulation of protein-plasma membrane targeting GOC:TermGenie up regulation of protein targeting to plasma membrane GOC:TermGenie up regulation of protein-plasma membrane targeting GOC:TermGenie up-regulation of protein targeting to plasma membrane GOC:TermGenie up-regulation of protein-plasma membrane targeting GOC:TermGenie upregulation of protein targeting to plasma membrane GOC:TermGenie upregulation of protein-plasma membrane targeting GOC:TermGenie Any process that modulates the frequency, rate or extent of vacuolar transport. vw 2014-08-18T13:16:04Z biological_process GO:1903335 regulation of vacuolar transport GO:1903335 Any process that modulates the frequency, rate or extent of vacuolar transport. GOC:TermGenie GOC:vw GO_REF:0000058 Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. vw 2014-08-18T13:16:11Z down regulation of vacuolar transport down-regulation of vacuolar transport downregulation of vacuolar transport inhibition of vacuolar transport biological_process GO:1903336 negative regulation of vacuolar transport GO:1903336 Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. GOC:TermGenie GOC:vw GO_REF:0000058 down regulation of vacuolar transport GOC:TermGenie down-regulation of vacuolar transport GOC:TermGenie downregulation of vacuolar transport GOC:TermGenie inhibition of vacuolar transport GOC:TermGenie Any process that activates or increases the frequency, rate or extent of vacuolar transport. vw 2014-08-18T13:16:19Z up regulation of vacuolar transport up-regulation of vacuolar transport upregulation of vacuolar transport activation of vacuolar transport biological_process GO:1903337 positive regulation of vacuolar transport GO:1903337 Any process that activates or increases the frequency, rate or extent of vacuolar transport. GOC:TermGenie GOC:vw GO_REF:0000058 up regulation of vacuolar transport GOC:TermGenie up-regulation of vacuolar transport GOC:TermGenie upregulation of vacuolar transport GOC:TermGenie activation of vacuolar transport GOC:TermGenie Any process that modulates the frequency, rate or extent of nucleus organization. hjd 2014-08-20T19:36:16Z regulation of nuclear organisation regulation of nuclear organization biological_process regulation of nuclear morphology regulation of nuclear organization and biogenesis regulation of nucleus organization and biogenesis GO:1903353 regulation of nucleus organization GO:1903353 Any process that modulates the frequency, rate or extent of nucleus organization. GOC:TermGenie GO_REF:0000058 PMID:16943282 regulation of nuclear organisation GOC:TermGenie regulation of nuclear organization GOC:TermGenie regulation of nuclear morphology GOC:TermGenie regulation of nuclear organization and biogenesis GOC:TermGenie regulation of nucleus organization and biogenesis GOC:TermGenie The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. bf 2014-09-03T09:19:13Z reactive oxygen species anabolism reactive oxygen species biosynthesis reactive oxygen species formation reactive oxygen species synthesis biological_process ROS formation ROS generation reactive oxygen species generation GO:1903409 reactive oxygen species biosynthetic process GO:1903409 The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. GOC:PARL GOC:TermGenie GOC:bf GO_REF:0000068 PMID:24252804 reactive oxygen species anabolism GOC:TermGenie reactive oxygen species biosynthesis GOC:TermGenie reactive oxygen species formation GOC:TermGenie reactive oxygen species synthesis GOC:TermGenie ROS generation PMID:24252804 reactive oxygen species generation PMID:24252804 Any process that modulates the frequency, rate or extent of secretion by cell. pm 2014-10-08T13:24:59Z regulation of cellular secretion biological_process GO:1903530 regulation of secretion by cell GO:1903530 Any process that modulates the frequency, rate or extent of secretion by cell. GOC:TermGenie GOC:pm GO_REF:0000058 PMID:12130530 regulation of cellular secretion GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. pm 2014-10-08T13:25:08Z down regulation of cellular secretion down regulation of secretion by cell down-regulation of cellular secretion down-regulation of secretion by cell downregulation of cellular secretion downregulation of secretion by cell negative regulation of cellular secretion inhibition of cellular secretion inhibition of secretion by cell biological_process GO:1903531 negative regulation of secretion by cell GO:1903531 Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. GOC:TermGenie GOC:pm GO_REF:0000058 PMID:12130530 down regulation of cellular secretion GOC:TermGenie down regulation of secretion by cell GOC:TermGenie down-regulation of cellular secretion GOC:TermGenie down-regulation of secretion by cell GOC:TermGenie downregulation of cellular secretion GOC:TermGenie downregulation of secretion by cell GOC:TermGenie negative regulation of cellular secretion GOC:TermGenie inhibition of cellular secretion GOC:TermGenie inhibition of secretion by cell GOC:TermGenie Any process that activates or increases the frequency, rate or extent of secretion by cell. pm 2014-10-08T13:25:17Z positive regulation of cellular secretion up regulation of cellular secretion up regulation of secretion by cell up-regulation of cellular secretion up-regulation of secretion by cell upregulation of cellular secretion upregulation of secretion by cell activation of cellular secretion activation of secretion by cell biological_process GO:1903532 positive regulation of secretion by cell GO:1903532 Any process that activates or increases the frequency, rate or extent of secretion by cell. GOC:TermGenie GOC:pm GO_REF:0000058 PMID:12130530 positive regulation of cellular secretion GOC:TermGenie up regulation of cellular secretion GOC:TermGenie up regulation of secretion by cell GOC:TermGenie up-regulation of cellular secretion GOC:TermGenie up-regulation of secretion by cell GOC:TermGenie upregulation of cellular secretion GOC:TermGenie upregulation of secretion by cell GOC:TermGenie activation of cellular secretion GOC:TermGenie activation of secretion by cell GOC:TermGenie Any process that modulates the frequency, rate or extent of plasma membrane organization. al 2014-12-10T18:59:44Z regulation of plasma membrane organisation biological_process regulation of plasma membrane organization and biogenesis GO:1903729 regulation of plasma membrane organization GO:1903729 Any process that modulates the frequency, rate or extent of plasma membrane organization. GOC:TermGenie GO_REF:0000058 PMID:24514900 regulation of plasma membrane organisation GOC:TermGenie regulation of plasma membrane organization and biogenesis GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. https://github.com/geneontology/go-ontology/issues/22021 jl 2015-01-20T14:32:24Z down regulation of cellular protein localisation down regulation of cellular protein localization down-regulation of cellular protein localisation down-regulation of cellular protein localization downregulation of cellular protein localisation downregulation of cellular protein localization negative regulation of cellular protein localisation negative regulation of cellular protein localization inhibition of cellular protein localisation inhibition of cellular protein localization biological_process GO:1903828 negative regulation of protein localization GO:1903828 Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. GOC:TermGenie GOC:vw GO_REF:0000058 down regulation of cellular protein localisation GOC:TermGenie down regulation of cellular protein localization GOC:TermGenie down-regulation of cellular protein localisation GOC:TermGenie down-regulation of cellular protein localization GOC:TermGenie downregulation of cellular protein localisation GOC:TermGenie downregulation of cellular protein localization GOC:TermGenie negative regulation of cellular protein localisation GOC:TermGenie inhibition of cellular protein localisation GOC:TermGenie inhibition of cellular protein localization GOC:TermGenie Any process that activates or increases the frequency, rate or extent of a protein localization. https://github.com/geneontology/go-ontology/issues/22021 jl 2015-01-20T14:32:33Z positive regulation of cellular protein localisation positive regulation of cellular protein localization up regulation of cellular protein localisation up regulation of cellular protein localization up-regulation of cellular protein localisation up-regulation of cellular protein localization upregulation of cellular protein localisation upregulation of cellular protein localization biological_process GO:1903829 positive regulation of protein localization GO:1903829 Any process that activates or increases the frequency, rate or extent of a protein localization. GOC:TermGenie GOC:vw GO_REF:0000058 positive regulation of cellular protein localisation GOC:TermGenie up regulation of cellular protein localisation GOC:TermGenie up regulation of cellular protein localization GOC:TermGenie up-regulation of cellular protein localisation GOC:TermGenie up-regulation of cellular protein localization GOC:TermGenie upregulation of cellular protein localisation GOC:TermGenie upregulation of cellular protein localization GOC:TermGenie Any process that modulates the frequency, rate or extent of protein localization to cell periphery. sl 2015-06-22T22:09:25Z biological_process GO:1904375 regulation of protein localization to cell periphery GO:1904375 Any process that modulates the frequency, rate or extent of protein localization to cell periphery. GOC:TermGenie GO_REF:0000058 PMID:18216290 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. sl 2015-06-22T22:09:32Z down regulation of protein localization to cell periphery down-regulation of protein localization to cell periphery downregulation of protein localization to cell periphery inhibition of protein localization to cell periphery biological_process GO:1904376 negative regulation of protein localization to cell periphery GO:1904376 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. GOC:TermGenie GO_REF:0000058 PMID:18216290 down regulation of protein localization to cell periphery GOC:TermGenie down-regulation of protein localization to cell periphery GOC:TermGenie downregulation of protein localization to cell periphery GOC:TermGenie inhibition of protein localization to cell periphery GOC:TermGenie Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. sl 2015-06-22T22:09:37Z up regulation of protein localization to cell periphery up-regulation of protein localization to cell periphery upregulation of protein localization to cell periphery activation of protein localization to cell periphery biological_process GO:1904377 positive regulation of protein localization to cell periphery GO:1904377 Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. GOC:TermGenie GO_REF:0000058 PMID:18216290 up regulation of protein localization to cell periphery GOC:TermGenie up-regulation of protein localization to cell periphery GOC:TermGenie upregulation of protein localization to cell periphery GOC:TermGenie activation of protein localization to cell periphery GOC:TermGenie Any process that modulates the frequency, rate or extent of protein localization to cell cortex. es 2015-10-29T16:55:01Z regulation of protein localisation to cell cortex biological_process GO:1904776 An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. regulation of protein localization to cell cortex GO:1904776 Any process that modulates the frequency, rate or extent of protein localization to cell cortex. GOC:TermGenie GO_REF:0000058 PMID:17115027 regulation of protein localisation to cell cortex GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. es 2015-10-29T16:55:08Z down regulation of protein localisation to cell cortex down regulation of protein localization to cell cortex down-regulation of protein localisation to cell cortex down-regulation of protein localization to cell cortex downregulation of protein localisation to cell cortex downregulation of protein localization to cell cortex negative regulation of protein localisation to cell cortex inhibition of protein localisation to cell cortex inhibition of protein localization to cell cortex biological_process GO:1904777 An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. negative regulation of protein localization to cell cortex GO:1904777 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. GOC:TermGenie GO_REF:0000058 PMID:17115027 down regulation of protein localisation to cell cortex GOC:TermGenie down regulation of protein localization to cell cortex GOC:TermGenie down-regulation of protein localisation to cell cortex GOC:TermGenie down-regulation of protein localization to cell cortex GOC:TermGenie downregulation of protein localisation to cell cortex GOC:TermGenie downregulation of protein localization to cell cortex GOC:TermGenie negative regulation of protein localisation to cell cortex GOC:TermGenie inhibition of protein localisation to cell cortex GOC:TermGenie inhibition of protein localization to cell cortex GOC:TermGenie Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. es 2015-10-29T16:55:15Z positive regulation of protein localisation to cell cortex up regulation of protein localisation to cell cortex up regulation of protein localization to cell cortex up-regulation of protein localisation to cell cortex up-regulation of protein localization to cell cortex upregulation of protein localisation to cell cortex upregulation of protein localization to cell cortex activation of protein localisation to cell cortex activation of protein localization to cell cortex biological_process GO:1904778 An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. positive regulation of protein localization to cell cortex GO:1904778 Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. GOC:TermGenie GO_REF:0000058 PMID:17115027 positive regulation of protein localisation to cell cortex GOC:TermGenie up regulation of protein localisation to cell cortex GOC:TermGenie up regulation of protein localization to cell cortex GOC:TermGenie up-regulation of protein localisation to cell cortex GOC:TermGenie up-regulation of protein localization to cell cortex GOC:TermGenie upregulation of protein localisation to cell cortex GOC:TermGenie upregulation of protein localization to cell cortex GOC:TermGenie activation of protein localisation to cell cortex GOC:TermGenie activation of protein localization to cell cortex GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. mec 2016-02-05T09:59:24Z down regulation of establishment of protein localisation down regulation of establishment of protein localization down regulation of protein positioning down regulation of protein recruitment down-regulation of establishment of protein localisation down-regulation of establishment of protein localization down-regulation of protein positioning down-regulation of protein recruitment downregulation of establishment of protein localisation downregulation of establishment of protein localization downregulation of protein positioning downregulation of protein recruitment negative regulation of establishment of protein localisation negative regulation of protein positioning negative regulation of protein recruitment inhibition of establishment of protein localisation inhibition of establishment of protein localization inhibition of protein positioning inhibition of protein recruitment biological_process GO:1904950 negative regulation of establishment of protein localization GO:1904950 Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. GOC:TermGenie GO_REF:0000058 PMID:22761445 down regulation of establishment of protein localisation GOC:TermGenie down regulation of establishment of protein localization GOC:TermGenie down regulation of protein positioning GOC:TermGenie down regulation of protein recruitment GOC:TermGenie down-regulation of establishment of protein localisation GOC:TermGenie down-regulation of establishment of protein localization GOC:TermGenie down-regulation of protein positioning GOC:TermGenie down-regulation of protein recruitment GOC:TermGenie downregulation of establishment of protein localisation GOC:TermGenie downregulation of establishment of protein localization GOC:TermGenie downregulation of protein positioning GOC:TermGenie downregulation of protein recruitment GOC:TermGenie negative regulation of establishment of protein localisation GOC:TermGenie negative regulation of protein positioning GOC:TermGenie negative regulation of protein recruitment GOC:TermGenie inhibition of establishment of protein localisation GOC:TermGenie inhibition of establishment of protein localization GOC:TermGenie inhibition of protein positioning GOC:TermGenie inhibition of protein recruitment GOC:TermGenie Any process that activates or increases the frequency, rate or extent of establishment of protein localization. mec 2016-02-05T09:59:32Z positive regulation of establishment of protein localisation positive regulation of protein positioning positive regulation of protein recruitment up regulation of establishment of protein localisation up regulation of establishment of protein localization up regulation of protein positioning up regulation of protein recruitment up-regulation of establishment of protein localisation up-regulation of establishment of protein localization up-regulation of protein positioning up-regulation of protein recruitment upregulation of establishment of protein localisation upregulation of establishment of protein localization upregulation of protein positioning upregulation of protein recruitment activation of establishment of protein localisation activation of establishment of protein localization activation of protein positioning activation of protein recruitment biological_process GO:1904951 positive regulation of establishment of protein localization GO:1904951 Any process that activates or increases the frequency, rate or extent of establishment of protein localization. GOC:TermGenie GO_REF:0000058 PMID:22761445 positive regulation of establishment of protein localisation GOC:TermGenie positive regulation of protein positioning GOC:TermGenie positive regulation of protein recruitment GOC:TermGenie up regulation of establishment of protein localisation GOC:TermGenie up regulation of establishment of protein localization GOC:TermGenie up regulation of protein positioning GOC:TermGenie up regulation of protein recruitment GOC:TermGenie up-regulation of establishment of protein localisation GOC:TermGenie up-regulation of establishment of protein localization GOC:TermGenie up-regulation of protein positioning GOC:TermGenie up-regulation of protein recruitment GOC:TermGenie upregulation of establishment of protein localisation GOC:TermGenie upregulation of establishment of protein localization GOC:TermGenie upregulation of protein positioning GOC:TermGenie upregulation of protein recruitment GOC:TermGenie activation of establishment of protein localisation GOC:TermGenie activation of establishment of protein localization GOC:TermGenie activation of protein positioning GOC:TermGenie activation of protein recruitment GOC:TermGenie A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. bf 2016-03-08T14:18:10Z autophagic vacuole organization biological_process initial autophagic vacuole organization GO:1905037 autophagosome organization GO:1905037 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. GOC:PARL GOC:TermGenie GOC:bf PMID:22186024 autophagic vacuole organization GOC:TermGenie initial autophagic vacuole organization GOC:TermGenie Any process that modulates the frequency, rate or extent of protein localization to membrane. bc 2016-09-21T16:20:03Z regulation of protein localisation in membrane regulation of protein localization in membrane biological_process GO:1905475 regulation of protein localization to membrane GO:1905475 Any process that modulates the frequency, rate or extent of protein localization to membrane. GOC:PARL GOC:TermGenie GOC:bc GO_REF:0000058 PMID:26911690 regulation of protein localisation in membrane GOC:TermGenie regulation of protein localization in membrane GOC:TermGenie Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. bc 2016-09-21T16:20:10Z down regulation of protein localisation in membrane down regulation of protein localization in membrane down regulation of protein localization to membrane down-regulation of protein localisation in membrane down-regulation of protein localization in membrane down-regulation of protein localization to membrane downregulation of protein localisation in membrane downregulation of protein localization in membrane downregulation of protein localization to membrane negative regulation of protein localisation in membrane negative regulation of protein localization in membrane inhibition of protein localisation in membrane inhibition of protein localization in membrane inhibition of protein localization to membrane biological_process GO:1905476 negative regulation of protein localization to membrane GO:1905476 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. GOC:PARL GOC:TermGenie GOC:bc GO_REF:0000058 PMID:26911690 down regulation of protein localisation in membrane GOC:TermGenie down regulation of protein localization in membrane GOC:TermGenie down regulation of protein localization to membrane GOC:TermGenie down-regulation of protein localisation in membrane GOC:TermGenie down-regulation of protein localization in membrane GOC:TermGenie down-regulation of protein localization to membrane GOC:TermGenie downregulation of protein localisation in membrane GOC:TermGenie downregulation of protein localization in membrane GOC:TermGenie downregulation of protein localization to membrane GOC:TermGenie negative regulation of protein localisation in membrane GOC:TermGenie negative regulation of protein localization in membrane GOC:TermGenie inhibition of protein localisation in membrane GOC:TermGenie inhibition of protein localization in membrane GOC:TermGenie inhibition of protein localization to membrane GOC:TermGenie Any process that activates or increases the frequency, rate or extent of protein localization to membrane. bc 2016-09-21T16:20:18Z positive regulation of protein localisation in membrane positive regulation of protein localization in membrane up regulation of protein localisation in membrane up regulation of protein localization in membrane up regulation of protein localization to membrane up-regulation of protein localisation in membrane up-regulation of protein localization in membrane up-regulation of protein localization to membrane upregulation of protein localisation in membrane upregulation of protein localization in membrane upregulation of protein localization to membrane activation of protein localisation in membrane activation of protein localization in membrane activation of protein localization to membrane biological_process GO:1905477 positive regulation of protein localization to membrane GO:1905477 Any process that activates or increases the frequency, rate or extent of protein localization to membrane. GOC:PARL GOC:TermGenie GOC:bc GO_REF:0000058 PMID:26911690 positive regulation of protein localisation in membrane GOC:TermGenie positive regulation of protein localization in membrane GOC:TermGenie up regulation of protein localisation in membrane GOC:TermGenie up regulation of protein localization in membrane GOC:TermGenie up regulation of protein localization to membrane GOC:TermGenie up-regulation of protein localisation in membrane GOC:TermGenie up-regulation of protein localization in membrane GOC:TermGenie up-regulation of protein localization to membrane GOC:TermGenie upregulation of protein localisation in membrane GOC:TermGenie upregulation of protein localization in membrane GOC:TermGenie upregulation of protein localization to membrane GOC:TermGenie activation of protein localisation in membrane GOC:TermGenie activation of protein localization in membrane GOC:TermGenie activation of protein localization to membrane GOC:TermGenie The disaggregation of a nucleus into its constituent components. pr 2016-11-14T13:38:57Z cell nucleus disassembly biological_process GO:1905690 nucleus disassembly GO:1905690 The disaggregation of a nucleus into its constituent components. GOC:TermGenie GOC:autophagy GOC:pr GO_REF:0000079 cell nucleus disassembly GOC:TermGenie A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). bhm 2013-11-12T13:20:12Z cellular_component GO:1990234 transferase complex GO:1990234 A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). GOC:bhm PMID:16540464 A process in which a protein is transported to, or maintained in, the cell periphery. 2015-06-18T22:37:39Z biological_process GO:1990778 protein localization to cell periphery GO:1990778 A process in which a protein is transported to, or maintained in, the cell periphery. PMID:18216290 Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. https://github.com/geneontology/go-ontology/issues/22182 mcc 2015-09-10T08:16:02Z maintenance of vacuolar localization maintenance of vacuole localization maintenance of vacuole location maintenance of vacuolar location biological_process GO:1990849 vacuolar localization GO:1990849 Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. PMID:26283797 A macromolecular complex that contains both RNA and protein molecules. pr 2015-11-19T12:26:37Z GO:0030529 GO:1990903 Wikipedia:Ribonucleoprotein RNA-protein complex RNP protein-RNA complex extracellular ribonucleoprotein complex intracellular ribonucleoprotein complex cellular_component GO:1990904 ribonucleoprotein complex GO:1990904 A macromolecular complex that contains both RNA and protein molecules. GOC:krc GOC:vesicles Any process that modulates the frequency, rate or extent of multicellular organismal development. tb 2010-08-05T11:25:59Z biological_process GO:2000026 regulation of multicellular organismal development GO:2000026 Any process that modulates the frequency, rate or extent of multicellular organismal development. GOC:obol Any process that modulates the frequency, rate or extent of reproductive process. mah 2010-11-10T02:44:02Z biological_process GO:2000241 regulation of reproductive process GO:2000241 Any process that modulates the frequency, rate or extent of reproductive process. GOC:mah Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. mah 2010-11-10T02:44:05Z biological_process GO:2000242 negative regulation of reproductive process GO:2000242 Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. GOC:mah Any process that activates or increases the frequency, rate or extent of reproductive process. mah 2010-11-10T02:44:08Z biological_process GO:2000243 positive regulation of reproductive process GO:2000243 Any process that activates or increases the frequency, rate or extent of reproductive process. GOC:mah Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. vw 2010-12-10T11:54:19Z regulation of amino acid biosynthetic process regulation of cellular amino acid anabolism regulation of cellular amino acid biosynthesis regulation of cellular amino acid formation regulation of cellular amino acid synthesis biological_process GO:2000282 regulation of cellular amino acid biosynthetic process GO:2000282 Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. GOC:obol regulation of amino acid biosynthetic process GOC:obol regulation of cellular amino acid anabolism GOC:obol regulation of cellular amino acid biosynthesis GOC:obol regulation of cellular amino acid formation GOC:obol regulation of cellular amino acid synthesis GOC:obol Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. vw 2010-12-10T11:54:23Z negative regulation of amino acid anabolism negative regulation of amino acid biosynthesis negative regulation of amino acid formation negative regulation of amino acid synthesis negative regulation of cellular amino acid biosynthetic process biological_process GO:2000283 negative regulation of amino acid biosynthetic process GO:2000283 Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. GOC:obol negative regulation of amino acid anabolism GOC:obol negative regulation of amino acid biosynthesis GOC:obol negative regulation of amino acid formation GOC:obol negative regulation of amino acid synthesis GOC:obol negative regulation of cellular amino acid biosynthetic process GOC:obol Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. vw 2010-12-10T11:54:27Z positive regulation of amino acid anabolism positive regulation of amino acid biosynthesis positive regulation of amino acid formation positive regulation of amino acid synthesis positive regulation of cellular amino acid biosynthetic process biological_process GO:2000284 positive regulation of amino acid biosynthetic process GO:2000284 Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. GOC:obol positive regulation of amino acid anabolism GOC:obol positive regulation of amino acid biosynthesis GOC:obol positive regulation of amino acid formation GOC:obol positive regulation of amino acid synthesis GOC:obol positive regulation of cellular amino acid biosynthetic process GOC:obol Any process that modulates the frequency, rate or extent of RNA biosynthetic process. dph 2011-10-17T11:36:25Z regulation of RNA anabolism regulation of RNA biosynthesis regulation of RNA formation regulation of RNA synthesis biological_process GO:2001141 regulation of RNA biosynthetic process GO:2001141 Any process that modulates the frequency, rate or extent of RNA biosynthetic process. GOC:dph regulation of RNA anabolism GOC:obol regulation of RNA biosynthesis GOC:obol regulation of RNA formation GOC:obol regulation of RNA synthesis GOC:obol IAO:0000027 data item IAO:0000030 information content entity IAO:0000078 curation status specification The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting) PERSON:Bill Bug GROUP:OBI:<http://purl.obolibrary.org/obo/obi> OBI_0000266 curation status specification IAO:0000102 data about an ontology part is a data item about a part of an ontology, for example a term Person:Alan Ruttenberg data about an ontology part IAO:0000225 obsolescence reason specification The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology. PERSON: Alan Ruttenberg PERSON: Melanie Courtot obsolescence reason specification IAO:0000409 The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are "natural kinds" and the latter arbitrary collections of entities. A denotator type indicates how a term should be interpreted from an ontological perspective. Alan Ruttenberg Barry Smith, Werner Ceusters denotator type IDO:0000450 A disposition to initiate processes that result in a disorder. Albert Goldfain Alexander Diehl Lindsay Cowell pathogenicity A pathogenic disposition is realized in processes that create a disorder. The use of 'initiates' is intended to convey that a pathogenic disposition is realized when processes resulting in a disorder begin because of some action on the part of the bearer of the disposition. By this interpretation of 'initiates', disorder-causing entities such as glass, UV light, and toxins do not have a pathogenic disposition. pathogenic disposition IDO:0000528 A material entity with a pathogenic disposition. Albert Goldfain Alexander Diehl Lindsay Cowell pathogen IDO:0000626 A process by which a disorder comes into existence. Albert Goldfain Alexander Diehl Lindsay Cowell appearance of disorder GC_ID:1 PMID:30365038 PMID:32761142 ncbi_taxonomy all NCBITaxon:1 root NCBITaxon:1 all GC_ID:1 ncbi_taxonomy NCBITaxon:1206794 Ecdysozoa NCBITaxon:1206794 GC_ID:1 ncbi_taxonomy biota NCBITaxon:131567 cellular organisms NCBITaxon:131567 biota GC_ID:1 true yeasts ncbi_taxonomy NCBITaxon:147537 Saccharomycotina NCBITaxon:147537 true yeasts GC_ID:1 ncbi_taxonomy Archiascomycota NCBITaxon:147554 Schizosaccharomycetes NCBITaxon:147554 Archiascomycota GC_ID:1 PMID:10874751 PMID:11557979 ncbi_taxonomy NCBITaxon:197562 Pancrustacea NCBITaxon:197562 GC_ID:1 PMID:11557979 PMID:9727836 mandibulates ncbi_taxonomy NCBITaxon:197563 Mandibulata NCBITaxon:197563 mandibulates GC_ID:11 PMID:10425795 PMID:10425796 PMID:10425797 PMID:10490293 PMID:10843050 PMID:10939651 PMID:10939673 PMID:10939677 PMID:11211268 PMID:11321083 PMID:11321113 PMID:11411719 PMID:11540071 PMID:11542017 PMID:11542087 PMID:11760965 PMID:12054223 PMID:2112744 PMID:270744 PMID:32628106 PMID:36748408 PMID:7520741 PMID:8123559 PMID:8186100 PMID:8590690 PMID:9103655 PMID:9336922 eubacteria ncbi_taxonomy Monera Procaryotae Prokaryota Prokaryotae bacteria prokaryote prokaryotes NCBITaxon:2 Bacteria NCBITaxon:2 eubacteria Monera Procaryotae Prokaryota Prokaryotae bacteria prokaryote prokaryotes GC_ID:11 PMID:10425795 PMID:10425796 PMID:10425797 PMID:10490293 PMID:10843050 PMID:10939651 PMID:10939673 PMID:10939677 PMID:11211268 PMID:11321083 PMID:11321113 PMID:11411719 PMID:11540071 PMID:11541975 PMID:11542064 PMID:11542149 PMID:11760965 PMID:12054223 PMID:2112744 PMID:25527841 PMID:270744 PMID:32628106 PMID:36748408 PMID:8123559 PMID:8590690 PMID:9103655 PMID:9336922 ncbi_taxonomy Archaebacteria Mendosicutes Metabacteria Monera Procaryotae Prokaryota Prokaryotae archaea prokaryote prokaryotes NCBITaxon:2157 Archaea NCBITaxon:2157 Archaebacteria Mendosicutes Metabacteria Monera Procaryotae Prokaryota Prokaryotae archaea prokaryote prokaryotes GC_ID:1 PMID:23020233 PMID:30257078 eucaryotes eukaryotes ncbi_taxonomy Eucarya Eucaryotae Eukarya Eukaryotae eukaryotes NCBITaxon:2759 Eukaryota NCBITaxon:2759 eucaryotes eukaryotes Eucarya Eucaryotae Eukarya Eukaryotae eukaryotes GC_ID:1 ncbi_taxonomy Fungi/Metazoa group opisthokonts NCBITaxon:33154 Opisthokonta NCBITaxon:33154 Fungi/Metazoa group opisthokonts GC_ID:1 metazoans multicellular animals ncbi_taxonomy Animalia animals NCBITaxon:33208 Metazoa NCBITaxon:33208 metazoans multicellular animals Animalia animals GC_ID:1 ncbi_taxonomy NCBITaxon:33213 Bilateria NCBITaxon:33213 GC_ID:1 ncbi_taxonomy NCBITaxon:33317 Protostomia NCBITaxon:33317 GC_ID:1 ncbi_taxonomy NCBITaxon:34346 Schizosaccharomycetales NCBITaxon:34346 GC_ID:1 PMID:15689432 PMID:16151185 PMID:17010206 PMID:17051209 PMID:17572334 ncbi_taxonomy NCBITaxon:451864 Dikarya NCBITaxon:451864 GC_ID:1 ncbi_taxonomy NCBITaxon:451866 Taphrinomycotina NCBITaxon:451866 GC_ID:1 PMID:11062127 PMID:12684019 ncbi_taxonomy Mycota fungi NCBITaxon:4751 Fungi NCBITaxon:4751 Mycota fungi GC_ID:1 PMID:17572334 ascomycetes sac fungi ncbi_taxonomy ascomycete fungi NCBITaxon:4890 Ascomycota NCBITaxon:4890 ascomycetes sac fungi ascomycete fungi GC_ID:1 ncbi_taxonomy Hemiascomycetes NCBITaxon:4891 Saccharomycetes NCBITaxon:4891 Hemiascomycetes GC_ID:1 ncbi_taxonomy Endomycetales budding yeasts NCBITaxon:4892 Saccharomycetales NCBITaxon:4892 Endomycetales budding yeasts NCBITaxon:221665 NCBITaxon:44280 GC_ID:1 ncbi_taxonomy NCBITaxon:4893 Saccharomycetaceae NCBITaxon:4893 GC_ID:1 fission yeasts ncbi_taxonomy Schizosaccharomycetoideae NCBITaxon:4894 Schizosaccharomycetaceae NCBITaxon:4894 fission yeasts Schizosaccharomycetoideae GC_ID:1 ncbi_taxonomy NCBITaxon:4895 Schizosaccharomyces NCBITaxon:4895 NCBITaxon:45042 GC_ID:1 fission yeast ncbi_taxonomy Schizosaccharomyces malidevorans NCBITaxon:4896 Schizosaccharomyces pombe NCBITaxon:4896 fission yeast Schizosaccharomyces malidevorans NCBITaxon:36915 GC_ID:1 ncbi_taxonomy Pachytichospora NCBITaxon:4930 Saccharomyces NCBITaxon:4930 Pachytichospora NCBITaxon:41870 GC_ID:1 Saccharomyces cerevisiae 'var. diastaticus' baker's yeast brewer's yeast ncbi_taxonomy Candida robusta Mycoderma cerevisiae Saccharomyces capensis Saccharomyces diastaticus Saccharomyces italicus Saccharomyces oviformis Saccharomyces uvarum var. melibiosus NCBITaxon:4932 Saccharomyces cerevisiae NCBITaxon:4932 Saccharomyces cerevisiae 'var. diastaticus' baker's yeast brewer's yeast Candida robusta Mycoderma cerevisiae Saccharomyces capensis Saccharomyces diastaticus Saccharomyces italicus Saccharomyces oviformis Saccharomyces uvarum var. melibiosus GC_ID:1 true insects ncbi_taxonomy insects NCBITaxon:50557 Insecta NCBITaxon:50557 true insects insects GC_ID:1 ncbi_taxonomy NCBITaxon:6072 Eumetazoa NCBITaxon:6072 GC_ID:1 arthropods ncbi_taxonomy arthropods NCBITaxon:6656 Arthropoda NCBITaxon:6656 arthropods arthropods GC_ID:1 insects ncbi_taxonomy Atelocerata Tracheata Uniramia hexapods NCBITaxon:6960 Hexapoda NCBITaxon:6960 insects Atelocerata Tracheata Uniramia hexapods GC_ID:1 ncbi_taxonomy NCBITaxon:716545 saccharomyceta NCBITaxon:716545 GC_ID:1 ncbi_taxonomy NCBITaxon:88770 Panarthropoda NCBITaxon:88770 OBI:0100026 OGMS:0000045 A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. disorder A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities PATO:0000072 quality PATO:0000001 quality PATO:0000001 A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities PATOC:GVG A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance. concentration quality PATO:0000033 concentration of PATO:0000033 A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance. Wikipedia:http://en.wikipedia.org/wiki/concentration A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. quality PATO:0000051 morphology PATO:0000051 A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. PATOC:GVG A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). PATO:0001647 relational shape quality quality PATO:0000052 Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects. shape PATO:0000052 A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). PATOC:GVG A quality of a single process inhering in a bearer by virtue of the bearer's occurrence. PATO:0000156 PATO:0000158 temporal incidence quality PATO:0000057 occurrence PATO:0000057 A quality of a single process inhering in a bearer by virtue of the bearer's occurrence. PATOC:GVG quality PATO:0000068 TODO: define this or obsolete it and move children somewhere else. qualitative PATO:0000068 A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. quality PATO:0000069 deviation (from_normal) PATO:0000069 A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. PATOC:GVG The number of entities of this type that are part of the whole organism. PATO:0000053 PATO:0000071 PATO:0001169 PATO:0001226 presence or absence in organism quantitative quality count in organism number presence PATO:0000070 This term was originally named "presence". It has been renamed to reduce ambiguity. Consider annotating with the reciprocal relation,PATO:0001555, has_number_of. For example, rather than E=fin ray Q=count in organism C=10, say E=organism Q=has number of E2= fin ray C=10. amount PATO:0000070 The number of entities of this type that are part of the whole organism. PATOC:GVG A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation. sensitivity quality PATO:0000085 sensitivity toward PATO:0000085 A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation. PATOC:GVG A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. quality PATO:0000117 size PATO:0000117 A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. WordNet:WordNet A 1-D extent quality which is equal to the distance between two points. https://github.com/pato-ontology/pato/issues/337 quality PATO:0000122 Length often refers to the longer or longest dimension of an object, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. length PATO:0000122 A 1-D extent quality which is equal to the distance between two points. PATOC:GVG A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time. quality PATO:0000161 rate PATO:0000161 A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time. PATOC:melissa An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population. quality PATO:0000169 viability PATO:0000169 An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population. PATOC:GVG A quality of a process which ends earlier than the natural end time or reference process. PATO:0001508 abolished quality incomplete PATO:0000297 TODO: the definition is incorrect. See absent. arrested PATO:0000297 A quality of a process which ends earlier than the natural end time or reference process. PATOC:LC A quality inhering in a bearer by virtue of the bearer's deviation from normal or average. quality aberrant atypia atypical defective PATO:0000460 abnormal PATO:0000460 A quality inhering in a bearer by virtue of the bearer's deviation from normal or average. PATOC:GVG A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. quality average PATO:0000461 normal PATO:0000461 A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. PATOC:GVG A quality denoting the lack of an entity. PATO:0001996 absence absent from organism quality PATO:0000462 We recommend using the new absent terms (physical absence, absent anatomical entity, or absent process) instead of this class. This is a legacy term and will ultimately be obsoleted. See https://github.com/pato-ontology/pato/issues/331. absent PATO:0000462 A quality denoting the lack of an entity. thefreedictionary.:thefreedictionary. A quality inhering in a bearer by virtue of the bearer's existence. quality present in organism PATO:0000467 present PATO:0000467 A quality inhering in a bearer by virtue of the bearer's existence. PATOC:GVG An amount which is relatively high. PATO:0000420 PATO:0000650 increased number present in greater numbers in organism supernumerary quality accessory increased PATO:0000470 increased amount PATO:0000470 An amount which is relatively high. PATOC:GVG A duration quality of a process which is relatively high. PATO:0000715 high time increased period increased time quality chronic prolonged period slow time PATO:0000498 increased duration PATO:0000498 A duration quality of a process which is relatively high. PATOC:GVG A duration quality of a process which is relatively low. PATO:0000716 decreased period decreased time low period shortened period quality fast time PATO:0000499 decreased duration PATO:0000499 A duration quality of a process which is relatively low. PATOC:GVG A quality of a process which starts later than the natural start time or the reference process. quality late PATO:0000502 delayed PATO:0000502 A quality of a process which starts later than the natural start time or the reference process. PATOC:LC A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus. sensitive quality PATO:0000516 sensitive toward PATO:0000516 A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus. PATOC:GVG A length quality which is relatively large. long quality PATO:0000573 increased length PATO:0000573 A length quality which is relatively large. PATOC:GVG A length quality which is relatively small. short quality shortened stubby PATO:0000574 decreased length PATO:0000574 A length quality which is relatively small. PATOC:GVG A size quality which is relatively high. PATO:0001202 quality big enlarged expanded great large PATO:0000586 increased size PATO:0000586 A size quality which is relatively high. PATOC:GVG A size quality which is relatively low. hypoplasia underdeveloped quality reduced small tiny PATO:0000587 decreased size PATO:0000587 A size quality which is relatively low. PATOC:GVG A quality of a process which starts earlier than the natural start time or the reference process. PATO:0000691 PATO:0002086 advanced quality early precocious PATO:0000694 premature PATO:0000694 A quality of a process which starts earlier than the natural start time or the reference process. PATO:LC A viability quality inhering in a population by virtue of the bearer's long term survival inability. quality PATO:0000718 lethal (sensu genetics) PATO:0000718 A viability quality inhering in a population by virtue of the bearer's long term survival inability. PATOC:GVG A rate which is relatively low. slow rate quality PATO:0000911 decreased rate PATO:0000911 A rate which is relatively low. PATO:GVG A rate which is relatively high. fast rate high rate quality PATO:0000912 increased rate PATO:0000912 A rate which is relatively high. PATO:GVG A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus. resistance quality PATO:0001046 resistance to PATO:0001046 A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus. PATOC:GVG A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration. quality PATO:0001159 concentrated PATO:0001159 A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration. PATOC:GVG A concentration which is higher relative to the normal or average. high concentration quality PATO:0001162 increased concentration PATO:0001162 A concentration which is higher relative to the normal or average. PATOC:GVG A concentration which is lower relative to the normal or average. low concentration quality PATO:0001163 decreased concentration PATO:0001163 A concentration which is lower relative to the normal or average. PATOC:GVG A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus. resistant quality PATO:0001178 resistant to PATO:0001178 A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus. PATOC:GVG A quality which inheres in an process. PATO:0001239 PATO:0001240 quality of a process quality of occurrent quality of process relational quality of occurrent quality PATO:0001236 See comments of relational quality of a physical entity. process quality PATO:0001236 A quality which inheres in an process. PATOC:GVG A quality which inheres in a continuant. PATO:0001237 PATO:0001238 snap:Quality monadic quality of a continuant multiply inhering quality of a physical entity quality of a continuant quality of a single physical entity quality of an object quality of continuant monadic quality of an object monadic quality of continuant quality PATO:0001241 Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles. physical object quality PATO:0001241 A quality which inheres in a continuant. PATOC:GVG A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point. PATO:0000081 period quality time PATO:0001309 duration PATO:0001309 A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point. PATOC:mellybelly A monadic quality of continuant that exists at the cellular level of organisation. quality PATO:0001396 cellular quality PATO:0001396 A monadic quality of continuant that exists at the cellular level of organisation. PATOC:GVG A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. quality PATO:0001404 nucleate quality PATO:0001404 A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. PATOC:GVG A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. quality PATO:0001405 anucleate PATO:0001405 A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. Biology-online:Biology-online A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. quality PATO:0001406 binucleate PATO:0001406 A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. Biology-online:Biology-online A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. quality PATO:0001407 mononucleate PATO:0001407 A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. Biology-online:Biology-online A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation. sensitivity of occurrent quality PATO:0001457 sensitivity of a process PATO:0001457 A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation. PATOC:GVG A sensitivity toward an external stimulus which is higher than normal/average. high sensitivity toward increased sensitivity quality PATO:0001549 increased sensitivity toward PATO:0001549 A sensitivity toward an external stimulus which is higher than normal/average. PATO:GVG A sensitivity toward an external stimulus which is lower than normal/average. decreased sensitivity low sensitivity toward quality PATO:0001550 decreased sensitivity toward PATO:0001550 A sensitivity toward an external stimulus which is lower than normal/average. PATO:GVG A sensitivity of a process which is higher than normal or average. high sensitivity of occurrent increased sensitivity of occurrent quality PATO:0001551 increased sensitivity of a process PATO:0001551 A sensitivity of a process which is higher than normal or average. PATO:GVG A sensitivity of a process which is lower than normal or average. decreased sensitivity of occurrent low sensitivity of occurrent quality PATO:0001552 decreased sensitivity of a process PATO:0001552 A sensitivity of a process which is lower than normal or average. PATO:GVG The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts. OBO_REL:has_part extra or missing physical or functional parts has or lacks parts of type mereological quality number of quality cardinality number PATO:0001555 has number of PATO:0001555 The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts. PATOC:CJM A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity. quality PATO:0001558 lacking processual parts PATO:0001558 A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity. PATOC:GVG A quality of a process inhering in a bearer by virtue of the bearer's processual parts. quality PATO:0001564 extra or missing processual parts PATO:0001564 A quality of a process inhering in a bearer by virtue of the bearer's processual parts. PATOC:GVG A resistance to a stimulus which is relatively high. high resistance to increased resistance quality PATO:0001650 increased resistance to PATO:0001650 A resistance to a stimulus which is relatively high. PATOC:GVG A resistance to a stimulus which is relatively low. decreased resistance low resistance to quality PATO:0001651 decreased resistance to PATO:0001651 A resistance to a stimulus which is relatively low. PATOC:GVG A size quality inhering in an bearer by virtue of the bearer's extension in one dimension. 1-D size quality PATO:0001708 1-D extent PATO:0001708 A size quality inhering in an bearer by virtue of the bearer's extension in one dimension. PATOC:GVG The bearer of this quality has_part = n, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. having physical part quality PATO:0001905 has normal numbers of parts of type PATO:0001905 The bearer of this quality has_part = n, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. PATOC:CJM A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. quality PATO:0001908 multinucleate PATO:0001908 A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. PATOC:GVG An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. quality PATO:0001992 cellularity PATO:0001992 An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. PATOC:GVG A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. quality PATO:0001993 multicellular PATO:0001993 A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. PATOC:GVG A quality that inheres in an entire organism or part of an organism. quality PATO:0001995 organismal quality PATO:0001995 A quality that inheres in an entire organism or part of an organism. PATOC:CJM An amount which is relatively low. PATO:0000419 PATO:0000468 decreased number present in fewer numbers in organism quality decreased reduced subnumerary PATO:0001997 decreased amount PATO:0001997 An amount which is relatively low. PATOC:GVG The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. loss of quality PATO:0001999 lacks parts or has fewer parts of type PATO:0001999 The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. PATOC:CJM A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity. PATO:0001557 OBO_REL:lacks_part lacks all physical parts of type quality PATO:0002000 Example: [E=organism Q=lacks_all_parts_of_type E2=Wing] - applies to an organism. A relational quality in which the bearer entity has no parts of the specified type. The bearer of this quality has_part = 0 of the indicated entity type, where a comparable organism usually has at least 1 part of the same type. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e lacks all parts of type X at time t, then there exists no instances x of X at t such that x part_of e that has no wings, where wings are normally present in that organism type. In OWL this is equivalent to a restriction on the OBO_REL:has_part relation with cardinality=0, i.e has_part 0 E2. lacks all parts of type PATO:0002000 A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity. PATOC:CJM The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. PATO:0001569 decreased number of has decreased number of has fewer physical parts of type quality PATO:0002001 Example: [E=hand Q=has_fewer_parts_of_type E2=digit] - applies to an organism that has no less fingers than is normal for organisms of that type. has fewer parts of type PATO:0002001 The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. PATOC:CJM The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. PATO:0001560 has extra parts of has increased number of having extra physical parts having supernumerary physical parts increased number of quality PATO:0002002 In polydactyly, the bearer of the quality is the hand, and the entity type being counted is 'finger'. In EQ syntax, E=hand, Q=<this> E2=finger. has extra parts of type PATO:0002002 The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. PATOC:CJM An amount which normal. 2009-03-20T11:16:22Z present in normal numbers in organism quality PATO:0002050 normal amount PATO:0002050 An amount which normal. PATOC:GVG An occurrence which is relatively high. 2009-03-26T11:10:11Z increased incidence quality PATO:0002051 increased occurrence PATO:0002051 An occurrence which is relatively high. PATOC:GVG An occurrence which is relatively low. 2009-03-26T11:12:35Z decreased incidence quality PATO:0002052 decreased occurrence PATO:0002052 An occurrence which is relatively low. PATOC:GVG 2009-06-05T09:16:46Z quality PATO:0002062 physical quality of a process PATO:0002062 Having extra or fewer parts. 2009-09-21T10:41:58Z quality PATO:0002083 altered number of PATO:0002083 Having extra or fewer parts. PATOC:GVG A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism. 2009-10-30T05:04:06Z quality PATO:0002146 virulence PATO:0002146 A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism. https://orcid.org/0000-0001-5208-3432 https://orcid.org/0000-0001-8941-3984 A virulence that is relatively low. 2009-10-30T05:05:02Z attenuated quality PATO:0002147 reduced virulence PATO:0002147 A virulence that is relatively low. PATOC:GVG A virulence that is relatively high. 2009-10-30T05:13:10Z quality PATO:0002148 increased virulence PATO:0002148 A virulence that is relatively high. PATOC:GVG A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc. 2010-03-10T03:18:15Z PATO:0002061 relational molecular quality quality PATO:0002182 molecular quality PATO:0002182 A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc. PATOC:GVG A quality that has a value that is increased compared to normal or average. 2011-06-16T06:39:43Z quality PATO:0002300 increased quality PATO:0002300 A quality that has a value that is increased compared to normal or average. PATOC:GVG A quality that has a value that is decreased compared to normal or average. 2011-06-16T06:40:15Z quality PATO:0002301 decreased quality PATO:0002301 A quality that has a value that is decreased compared to normal or average. PATOC:GVG A quality of a process that has a value that is decreased compared to normal or average. 2011-06-16T06:50:59Z quality PATO:0002302 decreased process quality PATO:0002302 A quality of a process that has a value that is decreased compared to normal or average. PATOC:GVG A quality of an object that has a value that is decreased compared to normal or average. 2011-06-16T06:51:54Z quality PATO:0002303 decreased object quality PATO:0002303 A quality of an object that has a value that is decreased compared to normal or average. PATOC:GVG A quality of a process that has a value that is increased compared to normal or average. 2011-06-16T06:53:08Z quality PATO:0002304 increased process quality PATO:0002304 A quality of a process that has a value that is increased compared to normal or average. PATOC:GVG A quality of an object that has a value that is increased compared to normal or average. 2011-06-16T06:54:01Z quality PATO:0002305 increased object quality PATO:0002305 A quality of an object that has a value that is increased compared to normal or average. PATOC:GVG A temporal distribution pattern of process occurrences within a regulation/reference process. 2011-11-22T01:12:28Z quality PATO:0002323 temporal distribution quality PATO:0002323 A temporal distribution pattern of process occurrences within a regulation/reference process. PATOC:LC The temporal relation between the end of the process with respect to a reference process. 2011-11-23T11:46:00Z quality completeness extent PATO:0002324 offset quality PATO:0002324 The temporal relation between the end of the process with respect to a reference process. PATOC:LC completeness GOC:CJM extent GOC:CJM The temporal relation between the start of the process with respect to a reference process. 2011-11-23T11:47:34Z quality initiation PATO:0002325 onset quality PATO:0002325 The temporal relation between the start of the process with respect to a reference process. PATOC:LC A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. 2013-10-21T05:44:34Z quality PATO:0002505 nucleated PATO:0002505 A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. PATOC:GVG The ability of a pathogen to produce an infectious disease or disorder in an another organism. 2018-08-02T04:24:52Z quality PATO:0040003 pathogenicity PATO:0040003 The ability of a pathogen to produce an infectious disease or disorder in an another organism. https://orcid.org/0000-0001-8941-3984 A rate which is relatively normal. quality PATO:0045000 normal rate PATO:0045000 A quality of an object that has a value that is normal or average. 2017-12-21T14:11:01Z quality PATO:0045001 normal object quality PATO:0045001 A concentration which is relatively normal or average. 2017-12-22T14:16:43Z quality PATO:0045010 normal concentration PATO:0045010 A resistance to a stimulus which is relatively normal or average 2017-12-22T14:16:43Z quality PATO:0045047 normal resistance to PATO:0045047 A sensitivity toward an external stimulus which is relatively normal or average 2017-12-22T14:16:43Z quality PATO:0045049 normal sensitivity toward PATO:0045049 A size quality which is relatively normal or average 2017-12-22T14:16:43Z quality PATO:0045050 normal size PATO:0045050 A length quality which is relatively normal or average 2017-12-22T14:16:43Z quality PATO:0045054 normal length PATO:0045054 A quality of a process that has a value that is normal or average. 2017-12-21T14:11:01Z quality PATO:0045073 normal process quality PATO:0045073 A virulence which is relatively normal or average 2017-12-22T14:16:43Z quality PATO:0045080 normal virulence PATO:0045080 A duration quality of a process which is relatively normal. quality PATO:0045084 normal duration PATO:0045084 An occurrence which is relatively normal. quality PATO:0045086 normal occurrence PATO:0045086 A sensitivity of a process which is relatively normal. quality PATO:0045088 normal sensitivity of a process PATO:0045088 A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components. http://orcid.org/0000-0001-7258-9596 quality PATO:0070044 anatomical structure quality PATO:0070044 PHIPO:0000001 Any of the set of observable characteristics arising from the interaction of a potentially pathogenic organism with a host organism. alaynecuzick 2018-05-02T11:20:17Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen host interaction phenotype PHIPO:0000002 Any of the set of observable characteristics of a single organism resulting from the interaction of its genotype with the environment. alaynecuzick 2018-05-02T11:20:59Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. single species phenotype PHIPO:0000003 A single organism phenotype that is observed at the level of a tissue (eg leaf, inflorescence, ear or kidney). alaynecuzick 2018-05-02T11:21:13Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. tissue phenotype PHIPO:0000004 A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is unaffected (i.e the same as wild-type, it could be pathogenic or non-pathogenic). alaynecuzick 2018-05-04T12:38:43Z normal pathogenicity unaffected disease causing ability unaltered pathogenicity unchanged pathogenicity pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Can only apply to changes in the pathogen. unaffected pathogenicity PHIPO:0000005 A phenotype where the pathogenicity is abnormal (i.e different than wild-type) alaynecuzick 2018-05-04T12:39:00Z pathogen_host_interaction_phenotype obsolete abnormal pathogenicity true PHIPO:0000006 A phenotype that is relevant to pathogenicity. Pathogenicity is the ability of an organism, a pathogen, to produce an infectious disease in another organism alaynecuzick 2018-05-04T12:39:55Z disease causing ability pathogen_host_interaction_phenotype pathogenesis (related) qc_do_not_annotate qc_do_not_manually_annotate Can only apply to changes in the pathogen. Pathogenicity is a qualitative concept. pathogenicity phenotype PHIPO:0000007 A phenotype where the ability of a pathogen effector to produce an infectious disease is absent. alaynecuzick 2018-05-04T12:42:00Z pathogenic ability absent disease causing ability absent pathogen_host_interaction_phenotype qc_do_not_annotate For use in the annotation extension infective ability. Can only apply to changes in the pathogen. obsolete functional pathogen effector absent true PHIPO:0000008 A phenotype where the ability of a pathogen effector to produce an infectious disease is present. alaynecuzick 2018-05-04T12:42:16Z pathogenic ability present disease causing ability present pathogen_host_interaction_phenotype qc_do_not_annotate For use in the annotation extension infective ability. Can only apply to changes in the pathogen. obsolete functional pathogen effector present true PHIPO:0000009 A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is obtained (pathogenicity was absent and is now present). alaynecuzick 2018-05-04T12:45:12Z gain of disease causing ability pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Can only apply to changes in the pathogen. Note that this ability to cause pathogenicity is a feature of the pathogen. Therefore gain/loss of pathogenicity should never be dependent on changes to the host genotype, only on changes to the pathogen genotype. If you are annotating changes in disease presence or absence dependent on the changes to the host consider increased/decreased virulence phenotypes. gain of pathogenicity PHIPO:0000010 A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is abolished (pathogenicity was present and is now absent). alaynecuzick 2018-05-04T12:45:31Z abolished pathogenicity loss of disease causing ability pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Can only apply to changes in the pathogen. Note that this ability to cause pathogenicity is a feature of the pathogen. Therefore gain/loss of pathogenicity should never be dependent on changes to the host genotype, only on changes to the pathogen genotype. If you are annotating changes in disease presence or absence dependent on the changes to the host consider increased/decreased virulence phenotypes. Note that avirulence means loss of/abolished virulence in plant pathology terminology. loss of pathogenicity PHIPO:0000011 A phenotype that is relevant to virulence. Virulence is the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism. (Virulence is observed where pathogenicity is present). alaynecuzick 2018-05-04T13:02:03Z disease severity pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate Can apply to changes in the pathogen or the host. Virulence is a quantitative concept virulence phenotype PHIPO:0000012 A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is unchanged (i.e. the same degree of infectious disease as wild-type interaction). alaynecuzick 2018-05-04T13:02:23Z normal virulence unaffected disease severity pathogen_host_interaction_phenotype qc_do_not_annotate For use in the annotation extension infective ability. Can apply to changes in the pathogen or the host. unaffected virulence PHIPO:0000013 A phenotype where virulence is abnormal (i.e. different than wild-type). alaynecuzick 2018-05-04T13:02:39Z pathogen_host_interaction_phenotype obsolete abnormal virulence true PHIPO:0000014 A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is increased (i.e. more symptoms than normal). alaynecuzick 2018-05-04T13:07:31Z hypervirulence increased disease severity pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Can apply to changes in the pathogen or the host. increased virulence PHIPO:0000015 A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is decreased (i.e. fewer symptoms than normal). alaynecuzick 2018-05-04T13:08:10Z decreased virulence reduced disease severity pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Can apply to changes in the pathogen or the host. reduced virulence PHIPO:0000016 A single organism phenotype which is normal (i.e. the same as wild-type). alaynecuzick 2018-05-04T13:10:48Z single_species_phenotype normal single species phenotype PHIPO:0000017 A single organism phenotype which is abnormal (i.e. different than wild-type). alaynecuzick 2018-05-04T13:11:04Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate abnormal single species phenotype PHIPO:0000018 A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer lipid droplets than normal. alaynecuzick 2018-05-04T13:12:20Z FYPO:0002552 single_species_phenotype lipid droplets present in decreased numbers PHIPO:0000019 A lethal single organism cell level phenotype resulting from altering a gene product that is essential for the life of the organism. alaynecuzick 2018-05-04T13:12:47Z single_species_phenotype essential lethal inviable cell PHIPO:0000021 A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-05-04T13:15:05Z PHIPO:0000020 decreased resistance to chemical single_species_phenotype increased sensitivity to chemical during growth increased sensitivity to chemical PHIPO:0000022 A growth phenotype which describes the resistance of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-05-04T13:16:06Z PHIPO:0000412 single_species_phenotype increased resistance to chemical during growth increased resistance to chemical PHIPO:0000023 A pathogen penetration assay phenotype (assessing the organism's ability to penetrate a given substance/membrane) which is abnormal (i.e. different than wild-type). alaynecuzick 2018-05-04T13:16:54Z single_species_phenotype pathogen_phenotype obsolete abnormal penetration assay phenotype true PHIPO:0000024 A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is present. alaynecuzick 2018-05-04T13:17:08Z single_species_phenotype pathogen_phenotype pathogen penetration across the barrier present PHIPO:0000025 alaynecuzick 2018-05-04T13:17:46Z single_species_phenotype Is this a bit too specific? should this be with sexual reproduction? eg ustilago and rust fungus MU agrees REMOVE from penetration obsolete normal mating phenotype prior to penetration true PHIPO:0000026 A pathogen phenotype indicating that the pathogen is able to penetrate a given experimental substance/membrane in the same manner as the wild-type. alaynecuzick 2018-05-04T13:18:03Z no penetration defect single_species_phenotype pathogen_phenotype obsolete normal penetration true PHIPO:0000027 A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is normal (i.e indistinguishable from wild type). alaynecuzick 2018-05-04T13:19:13Z normal pathogen post penetration single_species_phenotype pathogen_phenotype normal pathogen growth after penetration of the barrier PHIPO:0000028 A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is normal (i.e same as wild-type) when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-05-04T13:19:44Z normal formation of pathogen infection structure normal pathogen pre penetration single_species_phenotype pathogen_phenotype normal formation of pathogen penetration structure PHIPO:0000029 alaynecuzick 2018-05-04T13:22:14Z single_species_phenotype Is this a bit too specific? should this be with reproduction? obsolete abnormal mating phenotype prior to penetration true PHIPO:0000030 A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is absent. alaynecuzick 2018-05-04T13:22:31Z penetration defect single_species_phenotype pathogen_phenotype pathogen penetration across the barrier absent PHIPO:0000031 A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abnormal (i.e indistinguishable from wild type). alaynecuzick 2018-05-04T13:22:52Z abnormal pathogen post penetration single_species_phenotype pathogen_phenotype abnormal pathogen growth after penetration of the barrier PHIPO:0000032 A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type) when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-05-04T13:23:06Z abnormal formation of pathogen infection structure abnormal pathogen pre penetration single_species_phenotype pathogen_phenotype abnormal formation of pathogen penetration structure PHIPO:0000033 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abnormal. alaynecuzick 2018-07-04T13:41:02Z pathogen_host_interaction_phenotype obsolete abnormal pathogen growth on host surface true PHIPO:0000034 A single species phenotype that is observed at the level of an individual cell. alaynecuzick 2018-07-04T13:41:14Z FYPO:0000002 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. cell phenotype PHIPO:0000035 A pathogen host phenotype where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction exhibits mutualism. alaynecuzick 2018-07-09T13:41:47Z pathogen_host_interaction_phenotype qc_extension_only mutualism present PHIPO:0000036 A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of lipid droplets is abnormal. alaynecuzick 2019-01-14T12:21:13Z FYPO:0000356 single_species_phenotype abnormal lipid droplet morphology PHIPO:0000038 A phenotype which affects the balance of symbiotic mutualism, mutualism describes an interaction between two symbionts (where the larger is usually the host), results in positive (beneficial) effects on reproduction and/or survival of both species. alaynecuzick 2018-07-10T11:52:04Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate mutualism phenotype PHIPO:0000039 A phenotype in which the interaction is the same as the wild-type, no asymptomatic colonisation or disease formation symptoms are visible. alaynecuzick 2018-07-10T11:52:33Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate Logical definition mutualism (GO:0085030) and (has_relative_magnitude some normal (PATO:0000461)) normal mutualism PHIPO:0000040 A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction. alaynecuzick 2018-07-10T11:53:05Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate Logical definition mutualism (GO:0085030) and (has_relative_magnitude some abnormal (PATO:0000460)) need to choose correct language for term name abnormal mutualism PHIPO:0000041 alaynecuzick 2018-07-13T11:54:28Z single_species_phenotype bacteria flagella aphid flight nematode wiggle fungi non-motile (apart from spores) also hosts obsolete normal motility phenotype true PHIPO:0000042 alaynecuzick 2018-07-13T11:54:54Z single_species_phenotype obsolete abnormal motility phenotype true PHIPO:0000043 A single species phenotype where reproduction is abnormal. alaynecuzick 2018-07-13T11:57:47Z single_species_phenotype abnormal reproduction phenotype PHIPO:0000044 A single species phenotype where reproduction is normal (indistinguishable from wild type). alaynecuzick 2018-07-13T11:58:15Z single_species_phenotype normal reproduction phenotype PHIPO:0000045 A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954). alaynecuzick 2018-07-13T12:08:15Z single_species_phenotype normal parthenogenesis normal asexual reproduction PHIPO:0000046 A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953). alaynecuzick 2018-07-13T12:09:04Z single_species_phenotype normal sexual reproduction PHIPO:0000047 A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954). alaynecuzick 2018-07-13T12:09:49Z single_species_phenotype abnormal parthenogenesis abnormal asexual reproduction PHIPO:0000048 A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is abnormal (GO:0019953). alaynecuzick 2018-07-13T12:10:14Z single_species_phenotype abnormal sexual reproduction PHIPO:0000049 A population phenotype in which the frequency of occurrence of sexual spores is increased. alaynecuzick 2018-07-13T12:16:49Z single_species_phenotype increased number of sexual spores PHIPO:0000050 A population phenotype in which the frequency of occurrence of sexual spores is decreased. alaynecuzick 2018-07-13T12:17:15Z single_species_phenotype decreased number of sexual spores PHIPO:0000051 A population phenotype in which the frequency of occurrence of asexual spores is increased. alaynecuzick 2018-07-13T12:18:08Z increased number of conidia single_species_phenotype increased number of asexual spores PHIPO:0000052 A population phenotype in which the frequency of occurrence of asexual spores is decreased. alaynecuzick 2018-07-13T12:18:34Z decreased number of conidia fewer conidia single_species_phenotype decreased number of asexual spores PHIPO:0000053 A reproductive phenotype in which the occurrence of asexual spore formation happens later than normal. alaynecuzick 2018-07-13T12:20:33Z single_species_phenotype delayed asexual sporulation PHIPO:0000054 A reproductive phenotype in which the occurrence of asexual spore formation happens sooner than normal. alaynecuzick 2018-07-13T12:22:31Z single_species_phenotype premature asexual sporulation PHIPO:0000055 A reproductive phenotype in which the occurrence of sexual spore formation happens later than normal. alaynecuzick 2018-07-13T12:23:43Z single_species_phenotype delayed sexual sporulation PHIPO:0000056 A reproductive phenotype in which the occurrence of sexual spore formation happens sooner than normal. alaynecuzick 2018-07-13T12:24:07Z single_species_phenotype premature sexual sporulation PHIPO:0000057 A population phenotype in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-07-13T12:25:33Z single_species_phenotype normal number of sexual spores PHIPO:0000058 alaynecuzick 2018-07-13T12:26:14Z single_species_phenotype obsolete normal timing in production of sexual spores true PHIPO:0000059 A population phenotype in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-07-13T12:27:14Z normal number of conidia single_species_phenotype normal number of asexual spores PHIPO:0000060 alaynecuzick 2018-07-13T12:27:45Z single_species_phenotype obsolete normal timing in production of asexual spores true PHIPO:0000061 A reproductive phenotype where asexual spores are absent (FAO:0000023). alaynecuzick 2018-07-13T12:28:57Z conidia absent single_species_phenotype asexual spores absent PHIPO:0000062 A reproductive phenotype where sexual spores are absent (FAO:0000017). alaynecuzick 2018-07-13T12:29:31Z single_species_phenotype sexual spores absent PHIPO:0000063 A reproductive phenotype where asexual spores are present (FAO:0000017). The product of meiosis. alaynecuzick 2018-07-13T12:29:58Z single_species_phenotype sexual spores present PHIPO:0000064 A reproductive phenotype where asexual spores are present (FAO:0000023). The product of mitosis. alaynecuzick 2018-07-13T12:30:18Z conidia present single_species_phenotype asexual spores present PHIPO:0000065 A reproductive morphology phenotype where the size of the asexual spore is increased. alaynecuzick 2018-07-13T12:32:36Z conidia increased in size single_species_phenotype asexual spores increased in size PHIPO:0000066 alaynecuzick 2018-07-13T12:33:03Z single_species_phenotype obsolete abnormal timing of asexual spore production true PHIPO:0000067 A reproductive morphology phenotype where the size of the asexual spore is decreased. alaynecuzick 2018-07-13T12:36:00Z conidia decreased in size single_species_phenotype asexual spores decreased in size PHIPO:0000068 A reproductive morphology phenotype where the size of the sexual spore is increased. alaynecuzick 2018-07-13T12:37:29Z single_species_phenotype sexual spores increased in size PHIPO:0000069 A reproductive morphology phenotype where the size of the sexual spore is decreased. alaynecuzick 2018-07-13T12:37:52Z single_species_phenotype sexual spores decreased in size PHIPO:0000070 A single species individual organism phenotype where the accumulation of coloring matter in a sexual spore cell is altered. alaynecuzick 2018-07-13T12:38:19Z single_species_phenotype altered in pigment accumulation in sexual spore PHIPO:0000071 A reproductive morphology phenotype where the size of the sexual spore is abnormal. alaynecuzick 2018-07-13T12:39:04Z single_species_phenotype abnormal sexual spore size PHIPO:0000072 A reproductive morphology phenotype where the shape of the sexual spore is abnormal. alaynecuzick 2018-07-13T12:39:34Z single_species_phenotype abnormal sexual spore shape PHIPO:0000073 A population phenotype in which the frequency of occurrence of sexual spores is abnormal. alaynecuzick 2018-07-13T12:40:05Z single_species_phenotype abnormal number of sexual spores PHIPO:0000074 alaynecuzick 2018-07-13T12:42:05Z single_species_phenotype obsolete abnormal timing of sexual spore production true PHIPO:0000075 A reproductive morphology phenotype where the shape of the asexual spore is abnormal. alaynecuzick 2018-07-13T12:43:06Z abnormal conidia shape single_species_phenotype abnormal asexual spore shape PHIPO:0000076 A single species individual organism phenotype where the accumulation of coloring matter in an asexual spore cell is altered. alaynecuzick 2018-07-13T12:43:42Z altered in pigment accumulation in conidia single_species_phenotype altered in pigment accumulation in asexual spore PHIPO:0000077 A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is abnormal (GO:0034293). alaynecuzick 2018-07-13T12:54:33Z abnormal meiotic sporulation abnormal sexual spore formation single_species_phenotype abnormal sexual sporulation PHIPO:0000078 A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436). alaynecuzick 2018-07-13T12:55:38Z abnormal asexual spore formation abnormal mitotic sporulation single_species_phenotype abnormal asexual sporulation PHIPO:0000079 A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is normal (GO:0034293). alaynecuzick 2018-07-13T12:56:11Z normal meiotic sporulation normal sexual spore formation single_species_phenotype normal sexual sporulation PHIPO:0000080 A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436). alaynecuzick 2018-07-13T12:57:46Z normal asexual spore formation normal mitotic sporulation single_species_phenotype normal asexual sporulation PHIPO:0000081 A reproductive morphology phenotype where the size of the asexual spore is abnormal. alaynecuzick 2018-07-13T13:08:40Z abnormal conidia size single_species_phenotype abnormal asexual spore size PHIPO:0000082 A population phenotype in which the frequency of occurrence of asexual spores is abnormal. alaynecuzick 2018-07-13T13:09:40Z abnormal number of conidia single_species_phenotype abnormal number of asexual spores PHIPO:0000083 alaynecuzick 2018-07-13T13:17:24Z single_species_phenotype obsolete abnormal asexual spore motility true PHIPO:0000084 alaynecuzick 2018-07-13T13:18:20Z single_species_phenotype obsolete increased asexual spore motility true PHIPO:0000085 alaynecuzick 2018-07-13T13:18:38Z single_species_phenotype obsolete decreased asexual spore motility true PHIPO:0000086 alaynecuzick 2018-07-13T13:21:21Z single_species_phenotype obsolete normal asexual spore motility true PHIPO:0000087 alaynecuzick 2018-07-13T13:25:48Z single_species_phenotype obsolete normal binary fission true PHIPO:0000088 alaynecuzick 2018-07-13T13:27:00Z single_species_phenotype obsolete normal budding true PHIPO:0000089 alaynecuzick 2018-07-13T13:27:51Z single_species_phenotype obsolete normal fragmentation true PHIPO:0000090 alaynecuzick 2018-07-13T13:28:15Z single_species_phenotype obsolete normal parthenogenesis true PHIPO:0000091 alaynecuzick 2018-07-13T13:30:12Z single_species_phenotype obsolete abnormal budding true PHIPO:0000092 alaynecuzick 2018-07-13T13:30:30Z single_species_phenotype obsolete abnormal binary fission true PHIPO:0000093 alaynecuzick 2018-07-13T13:31:01Z single_species_phenotype obsolete abnormal parthenogenesis true PHIPO:0000094 alaynecuzick 2018-07-13T13:38:56Z single_species_phenotype obsolete normal mitosis in asexual reproduction true PHIPO:0000095 alaynecuzick 2018-07-13T13:41:23Z single_species_phenotype obsolete abnormal mitosis in asexual reproduction true PHIPO:0000096 A reproductive process phenotype in which the second meiotic nuclear division is abnormal (GO:0007135). alaynecuzick 2018-07-13T13:42:09Z FYPO:0006526 abnormal second meiotic nuclear division single_species_phenotype abnormal meiosis II PHIPO:0000097 A reproductive process phenotype in which the first meiotic nuclear division is abnormal (GO:0007127). alaynecuzick FYPO:0003603 abnormal first meiotic nuclear division single_species_phenotype abnormal meiosis I PHIPO:0000098 A reproductive process phenotype in which the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)(GO:0007135). alaynecuzick 2018-07-13T13:43:09Z FYPO:0003798 normal second meiotic nuclear division single_species_phenotype normal meiosis II PHIPO:0000099 A reproductive process phenotype in which the first meiotic nuclear division is normal (GO:0007127). alaynecuzick 2018-07-13T13:43:30Z FYPO:0003563 normal first meiotic nuclear division single_species_phenotype normal meiosis I PHIPO:0000100 alaynecuzick 2018-07-17T10:24:59Z single_species_phenotype obsolete increased motility true PHIPO:0000101 alaynecuzick 2018-07-17T10:25:07Z single_species_phenotype obsolete decreased motility true PHIPO:0000102 alaynecuzick 2018-07-17T10:25:22Z single_species_phenotype obsolete loss of motility true PHIPO:0000103 alaynecuzick 2018-07-17T10:25:33Z single_species_phenotype obsolete gain of motility true PHIPO:0000104 A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T10:58:56Z increased size of infection structure single_species_phenotype pathogen_phenotype increased size of penetration structure PHIPO:0000105 A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:00:04Z decreased size of infection structure single_species_phenotype pathogen_phenotype decreased size of penetration structure PHIPO:0000106 A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:00:54Z increased number of infection structure single_species_phenotype pathogen_phenotype increased number of penetration structure PHIPO:0000107 A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:05:16Z decreased number of appressorium decreased number of infection structure single_species_phenotype pathogen_phenotype decreased number of penetration structure PHIPO:0000108 A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins later than normal when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:13:16Z delayed timing of infection structure formation single_species_phenotype pathogen_phenotype delayed timing of penetration structure formation PHIPO:0000109 A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:13:53Z premature infection structure formation single_species_phenotype pathogen_phenotype premature penetration structure formation PHIPO:0000110 A single species pathogen growth phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:16:18Z abolished formation of pathogen infection structure single_species_phenotype pathogen_phenotype abolished formation of pathogen penetration structure PHIPO:0000111 A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins later than normal when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T11:17:12Z single_species_phenotype pathogen_phenotype delayed pathogen penetration across the barrier PHIPO:0000112 alaynecuzick 2018-07-17T11:19:23Z single_species_phenotype pathogen_phenotype obsolete non-functional penetration structure present true PHIPO:0000113 Penetration structure formed but not functioning in the same manner as the wild type. alaynecuzick 2018-07-17T11:19:35Z single_species_phenotype pathogen_phenotype obsolete altered functionality of penetration structure true PHIPO:0000114 A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is increased. alaynecuzick 2018-07-17T11:22:58Z single_species_phenotype pathogen_phenotype increased pathogen penetration across the barrier PHIPO:0000115 A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is decreased alaynecuzick 2018-07-17T11:23:12Z single_species_phenotype pathogen_phenotype decreased pathogen penetration across the barrier PHIPO:0000116 A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abolished. alaynecuzick 2018-07-17T11:30:36Z single_species_phenotype pathogen_phenotype abolished pathogen growth after penetration of the barrier PHIPO:0000117 A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is increased. alaynecuzick 2018-07-17T11:30:56Z single_species_phenotype pathogen_phenotype increased pathogen growth after penetration of the barrier PHIPO:0000118 A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is decreased. alaynecuzick 2018-07-17T11:31:06Z single_species_phenotype pathogen_phenotype decreased pathogen growth after penetration of the barrier PHIPO:0000119 A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins later than normal. alaynecuzick 2018-07-17T11:31:15Z single_species_phenotype pathogen_phenotype delayed timing of pathogen growth after penetration of the barrier PHIPO:0000120 A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins sooner than normal. alaynecuzick 2018-07-17T11:31:21Z single_species_phenotype pathogen_phenotype premature pathogen growth after penetration of the barrier PHIPO:0000121 A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608). alaynecuzick 2018-07-17T11:44:01Z single_species_phenotype abnormal asexual reproductive structure development PHIPO:0000122 A reproductive phenotype where the process of endospore formation, in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell is abnormal. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. (GO:0034301) alaynecuzick 2018-07-17T11:46:50Z single_species_phenotype abnormal endospore formation PHIPO:0000124 alaynecuzick 2018-07-17T12:23:31Z single_species_phenotype pathogen_phenotype obsolete abnormal penetration structure present true PHIPO:0000125 alaynecuzick 2018-07-17T12:28:43Z single_species_phenotype pathogen_phenotype obsolete abnormal pathogen growth post penetration present true PHIPO:0000126 A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2018-07-17T12:39:33Z single_species_phenotype pathogen_phenotype premature pathogen penetration across the barrier PHIPO:0000127 A reproductive phenotype where the morphology of the asexual spore is abnormal (FAO:0000023). The product of mitosis. alaynecuzick 2018-07-17T13:01:41Z abnormal conidia morphology single_species_phenotype abnormal asexual spore morphology PHIPO:0000128 A reproductive phenotype where the morphology of the asexual spore is normal (FAO:0000023). The product of mitosis. alaynecuzick 2018-07-17T13:04:52Z normal conidia morphology single_species_phenotype normal asexual spore morphology PHIPO:0000129 A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is normal (GO:0048608). alaynecuzick 2018-07-17T13:06:10Z single_species_phenotype normal asexual reproductive structure development PHIPO:0000130 A reproductive phenotype where the morphology of the sexual spore is abnormal (FAO:0000017). The product of meiosis. alaynecuzick 2018-07-17T13:09:36Z single_species_phenotype abnormal sexual spore morphology PHIPO:0000131 A pathogen host interaction phenotype which affects the binding of one pathogen protein to one host protein. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:31:00Z pathogen_host_interaction_phenotype pathogen host protein-protein interaction phenotype PHIPO:0000132 A single species phenotype that affects the binding of one protein to another. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:31:27Z FYPO:0000702 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. protein-protein interaction phenotype PHIPO:0000133 A single species molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:32:39Z FYPO:0000704 single_species_phenotype abnormal protein-protein interaction PHIPO:0000134 A single species molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:33:02Z FYPO:0000703 single_species_phenotype normal protein-protein interaction PHIPO:0000135 A single species molecular function phenotype in which the binding of one protein to another does not occur. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:33:52Z FYPO:0000705 single_species_phenotype abolished protein-protein interaction PHIPO:0000136 A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:34:13Z FYPO:0001645 single_species_phenotype decreased protein-protein interaction PHIPO:0000137 A single species molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:34:28Z FYPO:0001571 single_species_phenotype increased protein-protein interaction PHIPO:0000138 A single species molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-13T13:35:56Z FYPO:0005119 single_species_phenotype no logical definition in FYPO for 'altered protein binding specificity' altered protein binding specificity PHIPO:0000139 A single species molecular function phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. alaynecuzick 2018-09-13T13:36:40Z FYPO:0003591 single_species_phenotype abnormal protein complex binding PHIPO:0000140 A single species molecular function phenotype in which the binding of one protein to another occurs for a shorter time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:37:50Z FYPO:0005785 single_species_phenotype logical definition needs checking. decreased duration of protein-protein interaction PHIPO:0000141 A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent, and for a shorter time, than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-09-13T13:38:26Z FYPO:0005784 single_species_phenotype logical definition needs checking. decreased extent and duration of protein-protein interaction PHIPO:0000142 A single organism phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-13T13:44:08Z FYPO:0002131 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. RNA binding phenotype PHIPO:0000143 A single organism phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-13T13:44:19Z FYPO:0000653 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. DNA binding phenotype PHIPO:0000144 A single species molecular function phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. alaynecuzick 2018-09-24T13:14:19Z FYPO:0005232 single_species_phenotype normal protein complex binding PHIPO:0000145 A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:33:07Z FYPO:0000656 single_species_phenotype abnormal DNA binding PHIPO:0000146 A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:33:18Z FYPO:0000655 single_species_phenotype Logical defintion quality (PATO:0000001) and (inheres_in some DNA binding (GO:0003677)) and (qualifier (??) some normal PATO:0000461) normal DNA binding PHIPO:0000147 A single organism (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:34:30Z FYPO:0000659 single_species_phenotype abolished DNA binding PHIPO:0000148 A single organism (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:34:56Z FYPO:0003735 single_species_phenotype no logical definition for 'altered DNA binding specificity' in FYPO altered DNA binding specificity PHIPO:0000149 A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:35:16Z FYPO:0000658 single_species_phenotype decreased DNA binding PHIPO:0000150 A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:35:28Z FYPO:0000657 single_species_phenotype increased DNA binding PHIPO:0000151 A single organism (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes. alaynecuzick 2018-09-25T13:36:17Z FYPO:0006555 single_species_phenotype no logical definition for 'abnormal multiple protein binding to DNA' in FYPO abnormal multiple protein binding to DNA PHIPO:0000152 A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. 2018-09-25T13:37:19Z FYPO:0002132 single_species_phenotype abnormal RNA binding PHIPO:0000153 A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:37:37Z FYPO:0002357 single_species_phenotype normal RNA binding PHIPO:0000154 A single organism (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:37:57Z FYPO:0002133 single_species_phenotype abolished RNA binding PHIPO:0000155 A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:38:20Z FYPO:0002134 single_species_phenotype decreased RNA binding PHIPO:0000156 A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-09-25T13:38:31Z FYPO:0002135 single_species_phenotype increased RNA binding PHIPO:0000157 alaynecuzick 2018-10-01T12:11:36Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete motility phenotype true PHIPO:0000158 A single species phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T12:12:12Z FYPO:0001092 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. binding phenotype PHIPO:0000159 A single species phenotype in which the amount, distribution, composition or morphology of a cell part is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-01T12:12:52Z FYPO:0001233 single_species_phenotype normal subcellular component PHIPO:0000160 A single species phenotype which affects the pathogen's ability to penetrate a given experimental substance/membrane in an in vitro assay. alaynecuzick 2018-10-01T12:13:47Z single_species_phenotype pathogen_phenotype qc_do_not_annotate qc_do_not_manually_annotate Penetration assays are often performed in vitro to assess pathogen penetration machinery. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen penetration across barrier phenotype PHIPO:0000161 A single species phenotype which affects the reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). alaynecuzick 2018-10-01T12:14:40Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. reproductive phenotype PHIPO:0000162 A single species population growth phenotype that affects the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction). alaynecuzick 2018-10-01T12:15:24Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. unicellular population growth phenotype PHIPO:0000164 A pathogen host interaction phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T12:21:51Z pathogen_host_interaction_phenotype pathogen host interaction binding phenotype PHIPO:0000165 alaynecuzick 2018-10-01T12:22:45Z pathogen_host_interaction_phenotype obsolete abnormal host lesion formation with pathogen true PHIPO:0000166 alaynecuzick 2018-10-01T12:46:24Z single_species_phenotype obsolete chlorosis phenotype true PHIPO:0000167 A pathogen host interaction phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T12:54:51Z FYPO:0002131 pathogen_host_interaction_phenotype obsolete pathogen host interaction RNA binding phenotype true PHIPO:0000168 A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T12:56:01Z FYPO:0002132 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction RNA binding true PHIPO:0000169 alaynecuzick 2018-10-01T12:56:11Z single_species_phenotype obsolete chlorosis absent true PHIPO:0000170 alaynecuzick 2018-10-01T12:57:11Z single_species_phenotype obsolete chlorosis present true PHIPO:0000171 A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T12:57:15Z FYPO:0002357 pathogen_host_interaction_phenotype obsolete normal pathogen host interaction RNA binding true PHIPO:0000172 A pathogen host interaction (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:04:43Z FYPO:0002133 pathogen_host_interaction_phenotype obsolete abolished pathogen host interaction RNA binding true PHIPO:0000173 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abolished (it was present and is now absent). alaynecuzick 2018-10-01T13:04:47Z pathogen_host_interaction_phenotype abolished filamentous growth on host surface PHIPO:0000174 A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:05:26Z FYPO:0002134 pathogen_host_interaction_phenotype obsolete decreased pathogen host interaction RNA binding true PHIPO:0000175 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is normal. alaynecuzick 2018-10-01T13:05:29Z pathogen_host_interaction_phenotype obsolete normal pathogen growth on host surface true PHIPO:0000176 A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:05:50Z FYPO:0002135 pathogen_host_interaction_phenotype obsolete increased pathogen host interaction RNA binding true PHIPO:0000177 A single species population phenotype in which affects the population growth during the yeast-form lifecycle stage. alaynecuzick 2018-10-01T13:05:53Z single_species_phenotype obsolete yeast-form growth phenotype true PHIPO:0000178 A pathogen host interaction phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:09:13Z FYPO:0000653 pathogen_host_interaction_phenotype obsolete pathogen host interaction DNA binding phenotype true PHIPO:0000180 A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:09:23Z FYPO:0000656 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction DNA binding true PHIPO:0000182 A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is absent. alaynecuzick 2018-10-01T13:09:35Z PHIPO:0000186 abolished host HR induced by pathogen during biotrophy absence of host HR induced by pathogen during biotrophy pathogen_host_interaction_phenotype abolished effector-mediated host hypersensitive response during biotrophy abolished host lesion abolished host necrotic cell death absence of effector-mediated host hypersensitive response during biotrophy absence of host lesion absence of host necrotic cell death This term is to be used for host protection against the pathogen. Note that if you are curating a necrotroph you need to annotate to PHIPO:0000465. absence of host-defense induced lesion by host hypersensitive response PHIPO:0000183 A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:09:42Z FYPO:0000655 pathogen_host_interaction_phenotype Logical defintion quality (PATO:0000001) and (inheres_in some DNA binding (GO:0003677)) and (qualifier (??) some normal PATO:0000461) obsolete normal pathogen host interaction DNA binding true PHIPO:0000184 alaynecuzick 2018-10-01T13:12:32Z pathogen_host_interaction_phenotype obsolete pathogen adhesion to host phenotype true PHIPO:0000185 A pathogen host interaction (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes. alaynecuzick 2018-10-01T13:12:43Z FYPO:0006555 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction multiple protein binding to DNA true PHIPO:0000187 A pathogen host interaction (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:13:16Z FYPO:0000659 pathogen_host_interaction_phenotype obsolete abolished pathogen host interaction DNA binding true PHIPO:0000188 A pathogen colonization of host phenotype which affects the vegetative growth or proliferation of the pathogen on the host surface. alaynecuzick 2018-10-01T13:13:27Z pathogen_host_interaction_phenotype pathogen growth on host surface phenotype PHIPO:0000189 A pathogen host interaction (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:13:36Z FYPO:0003735 pathogen_host_interaction_phenotype obsolete altered pathogen host interaction DNA binding specificity true PHIPO:0000190 A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense is delayed. alaynecuzick 2018-10-01T13:14:10Z pathogen_host_interaction_phenotype delayed effector-mediated host hypersensitive response during biotrophy delayed host necrotic cell death delayed presence of host lesion This term is to be used for host protection against the pathogen. delayed host-defense induced lesion formation by host hypersensitive response PHIPO:0000191 A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:14:20Z FYPO:0000658 pathogen_host_interaction_phenotype obsolete decreased pathogen host interaction DNA binding true PHIPO:0000192 A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is present. alaynecuzick 2018-10-01T13:14:29Z PHIPO:0000516 pathogen_host_interaction_phenotype gain of effector-mediated host hypersensitive response during biotrophy gain of host necrotic cell death gain of presence of host lesion presence of effector-mediated host hypersensitive response during biotrophy presence of host lesion presence of host necrotic cell death This term is to be used for host protection against the pathogen. Note that if you are curating a necrotroph you need to annotate to PHIPO:0000477. presence of host-defense induced lesion by host hypersensitive response PHIPO:0000193 A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-10-01T13:14:39Z FYPO:0000657 pathogen_host_interaction_phenotype obsolete increased pathogen host interaction DNA binding true PHIPO:0000195 alaynecuzick 2018-10-01T13:26:34Z pathogen_host_interaction_phenotype obsolete normal host lesion formation with pathogen true PHIPO:0000196 An individual organism growth phenotype in which the aerial height of hyphae is normal (indistinguishable from wild type). alaynecuzick 2018-10-01T13:27:25Z single_species_phenotype normal aerial height of filamentous colony Although this phenotype is for an individual it can be inferred from a population in a colony. normal aerial height of filament PHIPO:0000197 A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-10-01T13:27:34Z FYPO:0000704 pathogen_host_interaction_phenotype obsolete abnormal pathogen host protein protein interaction true PHIPO:0000198 A pathogen host interaction phenotype which affects a transporter activity. alaynecuzick 2018-10-01T13:27:49Z pathogen_host_interaction_phenotype obsolete pathogen host interaction transporter phenotype true PHIPO:0000199 A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. alaynecuzick 2018-10-01T13:27:56Z FYPO:0000703 pathogen_host_interaction_phenotype obsolete normal pathogen host protein protein interaction true PHIPO:0000200 A pathogen-host interaction phenotype in which leaves produce insufficient chlorophyll. alaynecuzick 2018-10-01T13:28:13Z pathogen_host_interaction_phenotype host chlorosis phenotype in presence of pathogen PHIPO:0000201 A pathogen (molecular function??) phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. alaynecuzick 2018-10-01T13:28:22Z FYPO:0005232 pathogen_host_interaction_phenotype obsolete normal pathogen host protein complex binding true PHIPO:0000202 A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. alaynecuzick 2018-10-01T13:31:30Z FYPO:0003591 pathogen_host_interaction_phenotype obsolete abnormal pathogen host protein complex binding true PHIPO:0000203 A single species hyphal colony shape phenotype where the aerial height of the filamentous colony is increased. alaynecuzick 2018-10-01T13:31:34Z single_species_phenotype increased aerial height of filamentous colony obsolete increased aerial height of filamentous colony affecting colony shape true PHIPO:0000205 An individual organism growth phenotype in which the aerial height of hyphae is decreased. alaynecuzick 2018-10-01T13:32:01Z single_species_phenotype decreased aerial height of filamentous colony Although this phenotype is for an individual it can be inferred from a population in a colony. decreased aerial height of filament PHIPO:0000206 A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs with a different specificity than normal. alaynecuzick 2018-10-01T13:32:15Z FYPO:0005119 pathogen_host_interaction_phenotype obsolete altered pathogen and host protein binding specificity true PHIPO:0000207 A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction and the endosymbiont organism is able to show greater biomass within the host and/or the formation of visible disease formation symptoms compared to the normal interaction. alaynecuzick 2018-10-01T13:32:18Z pathogen_host_interaction_phenotype qc_extension_only loss of mutualism PHIPO:0000208 A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs for a shorter time than normal. alaynecuzick 2018-10-01T13:32:28Z FYPO:0005785 pathogen_host_interaction_phenotype obsolete decreased duration of pathogen host protein-protein interaction true PHIPO:0000209 alaynecuzick 2018-10-01T13:32:31Z single_species_phenotype obsolete increased stature true PHIPO:0000210 A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lower extent, and for a shorter time, than normal. alaynecuzick 2018-10-01T13:32:42Z FYPO:0005784 pathogen_host_interaction_phenotype obsolete decreased extent and duration of pathogen host protein-protein interaction true PHIPO:0000211 alaynecuzick 2018-10-01T13:32:46Z single_species_phenotype obsolete decreased stature true PHIPO:0000212 A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lesser extent than normal. alaynecuzick 2018-10-01T13:33:00Z FYPO:0001645 pathogen_host_interaction_phenotype decreased pathogen host protein-protein interaction PHIPO:0000213 A pathogen-host interaction phenotype in which host chlorosis is absent. alaynecuzick 2018-10-01T13:33:03Z pathogen_host_interaction_phenotype host chlorosis absent in presence of pathogen PHIPO:0000214 A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a greater extent than normal. alaynecuzick 2018-10-01T13:33:15Z FYPO:0001571 pathogen_host_interaction_phenotype increased pathogen host protein-protein interaction PHIPO:0000215 A pathogen-host interaction phenotype in which host chlorosis is present. alaynecuzick 2018-10-01T13:33:18Z pathogen_host_interaction_phenotype host chlorosis present in presence of pathogen PHIPO:0000216 alaynecuzick 2018-10-01T13:42:29Z pathogen_host_interaction_phenotype obsolete pathogen host interaction disease symptom phenotype true PHIPO:0000217 A pathogen host interaction phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. alaynecuzick 2018-10-01T13:43:20Z GO:0044238 pathogen_host_interaction_phenotype Definition adapted from GO:0044238 primary metabolic process obsolete pathogen host interaction primary metabolic process phenotype true PHIPO:0000218 A pathogen host interaction phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type). alaynecuzick 2018-10-01T13:43:40Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction toxin biosynthetic process true PHIPO:0000219 A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is lower than normal. alaynecuzick 2018-10-01T13:44:10Z decreased level of pathogen DON within host decreased level of pathogen vomitoxin within host pathogen_host_interaction_phenotype decreased level of pathogen deoxynivalenol within host PHIPO:0000220 A pathogen host interaction phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. alaynecuzick 2018-10-02T08:53:44Z GO_0008152 pathogen_host_interaction_phenotype Definition adapted from GO_0008152 metabolic process obsolete pathogen host interaction metabolic process phenotype true PHIPO:0000224 alaynecuzick 2018-10-02T08:59:23Z pathogen_host_interaction_phenotype obsolete altered colour of host lesion with pathogen true PHIPO:0000226 A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. alaynecuzick 2018-10-02T09:09:52Z GO:0044550 pathogen_host_interaction_phenotype Definition adapted from GO:0044550 secondary metabolite biosynthetic process obsolete pathogen host interaction secondary metabolite biosynthetic process phenotype true PHIPO:0000227 A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. alaynecuzick 2018-10-02T09:10:09Z GO:0019748 pathogen_host_interaction_phenotype Definition adapted from GO:0019748 secondary metabolic process obsolete pathogen host interaction secondary metabolic process phenotype true PHIPO:0000228 A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is normal (i.e. same as the wild type). alaynecuzick 2018-10-02T09:12:44Z pathogen_host_interaction_phenotype obsolete normal pathogen host interaction biosynthesis of deoxynivalenol true PHIPO:0000229 A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type). alaynecuzick 2018-10-02T09:12:59Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction biosynthesis of deoxynivalenol true PHIPO:0000230 A pathogen host interaction phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type). alaynecuzick 2018-10-02T09:15:34Z pathogen_host_interaction_phenotype obsolete normal pathogen host interaction toxin biosynthetic process true PHIPO:0000231 A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. alaynecuzick 2018-10-02T09:17:44Z GO:0009403 pathogen_host_interaction_phenotype Definition adapted fromo GO:0009403 toxin biosynthetic process obsolete pathogen host interaction toxin biosynthetic process phenotype true PHIPO:0000232 A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is higher than normal. alaynecuzick 2018-10-02T09:18:35Z increased level of pathogen DON within host increased level of pathogen vomitoxin within host pathogen_host_interaction_phenotype increased level of pathogen deoxynivalenol within host PHIPO:0000233 A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is present as normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-02T09:19:27Z pathogen DON within host present pathogen vomitoxin within host present pathogen_host_interaction_phenotype presence of pathogen deoxynivalenol within host pathogen deoxynivalenol within host present PHIPO:0000234 A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is absent or at a level too low to detect. alaynecuzick 2018-10-02T09:20:17Z pathogen DON within host absent pathogen vomitoxin within host absent pathogen_host_interaction_phenotype absence of pathogen deoxynivalenol within host pathogen deoxynivalenol within host absent PHIPO:0000235 A single species phenotype that affects the localization of a structure or substance in a cell. alaynecuzick 2018-10-02T10:12:56Z FYPO:0000138 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. localization phenotype PHIPO:0000236 A pathogen host interaction phenotype that affects the localization of a structure or substance in a cell. alaynecuzick 2018-10-02T10:13:04Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate Note that this term was reinstated from obsolete. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen host interaction localization phenotype PHIPO:0000237 A single organism phenotype that affects the localization of a protein in a cell. alaynecuzick 2018-10-02T10:13:36Z FYPO:0002333 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. protein localization phenotype PHIPO:0000238 A pathogen host interaction phenotype that affects the localization of a protein in a cell. alaynecuzick 2018-10-02T10:13:39Z FYPO:0002333 pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete pathogen host interaction protein localization phenotype true PHIPO:0000239 A single organism phenotype in which the localization of a protein in a cell is abnormal. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. alaynecuzick 2018-10-02T10:14:02Z FYPO:0001370 single_species_phenotype abnormal protein localization PHIPO:0000240 A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell differs from normal. alaynecuzick 2018-10-02T10:14:05Z pathogen_host_interaction_phenotype abnormal pathogen protein localization within host PHIPO:0000241 A single organism phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal. alaynecuzick 2018-10-02T10:14:50Z FYPO:0001440 single_species_phenotype abnormal protein complex localization PHIPO:0000242 A pathogen host interaction phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal. alaynecuzick 2018-10-02T10:14:53Z FYPO:0001440 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction protein complex localization true PHIPO:0000243 A pathogen host interaction phenotype in which the localization of a protein to the nucleus is abnormal. (Which nucleus? pathogen or host?) alaynecuzick 2018-10-02T10:16:31Z FYPO:0002956 pathogen_host_interaction_phenotype Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. obsolete abnormal pathogen host interaction protein localization to nucleus true PHIPO:0000244 A single organism phenotype in which the localization of a protein to the nucleus is abnormal. alaynecuzick 2018-10-02T10:16:37Z FYPO:0002956 single_species_phenotype Encompasses both presence of proteins not normally found in the nucleus and decreased levels or absence of proteins normally found there, and describes defects in a localization process. We recommend noting which protein(s) were used in the assay when annotating to this term. abnormal protein localization to nucleus PHIPO:0000245 A single organism phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found. alaynecuzick 2018-10-02T10:17:52Z FYPO:0001375 single_species_phenotype If this term is used, we recommend noting which protein(s) were used in the assay. abolished protein localization PHIPO:0000246 A pathogen host interaction phenotype in which the localization of a pathogen protein to a host structure or compartment is abolished (i.e. the protein was localized to the host structure or compartment and now is not). alaynecuzick 2018-10-02T10:17:55Z FYPO:0001375 pathogen_host_interaction_phenotype If this term is used, we recommend noting which protein(s) were used in the assay. abolished pathogen protein localization within host PHIPO:0000247 A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is abolished. alaynecuzick 2018-10-02T10:19:22Z FYPO:0003450 pathogen_host_interaction_phenotype We recommend noting which protein(s) were used in the assay when annotating to this term. abolished pathogen protein localization to host nucleus PHIPO:0000248 A single organism phenotype in which the localization of a protein to the nucleus is abolished (GO:0034504). alaynecuzick 2018-10-02T10:19:27Z FYPO:0003450 single_species_phenotype We recommend noting which protein(s) were used in the assay when annotating to this term. abolished protein localization to nucleus PHIPO:0000249 A single organism phenotype that affects the localization of an RNA in a cell. alaynecuzick 2018-10-02T10:20:15Z FYPO:0004853 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. RNA localization phenotype PHIPO:0000250 A pathogen host interaction phenotype that affects the localization of an RNA in a cell. alaynecuzick 2018-10-02T10:20:17Z FYPO:0004853 pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete pathogen host interaction RNA localization phenotype true PHIPO:0000251 A single organism phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. alaynecuzick 2018-10-02T10:20:49Z FYPO:0003057 single_species_phenotype abnormal RNA localization PHIPO:0000252 A pathogen host interaction phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. alaynecuzick 2018-10-02T10:20:53Z FYPO:0003057 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction RNA localization true PHIPO:0000253 A single organism phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-02T10:21:19Z FYPO:0003058 single_species_phenotype normal RNA localization PHIPO:0000254 A pathogen host interaction phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-02T10:21:22Z FYPO:0003058 pathogen_host_interaction_phenotype obsolete normal pathogen host interaction RNA localization true PHIPO:0000255 A pathogen host interaction (cell process???) phenotype that affects a transport process. alaynecuzick 2018-10-02T10:21:45Z FYPO:0000149 pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete pathogen host interaction transport phenotype true PHIPO:0000256 A single organism cell phenotype that affects a transport process. alaynecuzick 2018-10-02T10:21:48Z FYPO:0000149 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. transport phenotype PHIPO:0000257 A single organism phenotype in which a specific transport process is abnormal. alaynecuzick 2018-10-02T10:22:11Z FYPO:0001720 single_species_phenotype abnormal transport PHIPO:0000258 A pathogen host interaction phenotype in which a specific transport process is abnormal. alaynecuzick 2018-10-02T10:22:15Z FYPO:0001720 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction transport true PHIPO:0000259 A single organism cellular process phenotype in which protein transport is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-02T10:22:37Z FYPO:0005747 single_species_phenotype normal protein transport PHIPO:0000260 A pathogen host interaction (cellular process??) phenotype in which protein transport is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-02T10:22:40Z FYPO:0005747 pathogen_host_interaction_phenotype obsolete normal pathogen host interaction protein transport true PHIPO:0000261 A single organism cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. alaynecuzick 2018-10-02T10:22:57Z FYPO:0003886 single_species_phenotype abnormal endocytosis PHIPO:0000262 A pathogen host interaction (cellular process???) phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. alaynecuzick 2018-10-02T10:23:00Z FYPO:0003886 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction endocytosis true PHIPO:0000263 A single organism cellular process phenotype in which nuclear transport is abnormal. alaynecuzick 2018-10-02T10:23:27Z FYPO:0005573 single_species_phenotype abnormal nuclear transport PHIPO:0000264 A pathogen host interaction (cellular process??) phenotype in which nuclear transport is abnormal. alaynecuzick 2018-10-02T10:23:30Z FYPO:0005573 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction nuclear transport true PHIPO:0000265 A single organism cellular process phenotype in which protein transport is abnormal. alaynecuzick 2018-10-02T10:24:39Z FYPO:0005744 single_species_phenotype abnormal protein transport PHIPO:0000266 A pathogen host interaction (cellular process??) phenotype in which protein transport is abnormal. alaynecuzick 2018-10-02T10:24:41Z FYPO:0005744 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction protein transport true PHIPO:0000267 A single organism cellular process phenotype in which vacuolar transport is abnormal. alaynecuzick 2018-10-02T10:24:58Z FYPO:0003578 single_species_phenotype abnormal vacuolar transport PHIPO:0000268 A pathogen host interaction (cellular process??) phenotype in which vacuolar transport is abnormal. alaynecuzick 2018-10-02T10:25:00Z FYPO:0003578 pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction vacuolar transport true PHIPO:0000269 A single organism phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-03T11:05:06Z FYPO:0003627 single_species_phenotype normal protein localization PHIPO:0000270 A pathogen host interaction phenotype, in which the colocalization of a pathogen protein and a host protein within a host cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-03T11:05:09Z pathogen_host_interaction_phenotype normal pathogen protein and host protein colocalization within host PHIPO:0000271 A single organism phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)(GO:0034504). alaynecuzick 2018-10-03T11:05:29Z FYPO:0006553 single_species_phenotype normal protein localization to nucleus PHIPO:0000272 A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-03T11:05:31Z FYPO:0006553 pathogen_host_interaction_phenotype normal pathogen protein localization to host nucleus PHIPO:0000274 A population phenotype in which the frequency of occurrence of asexual spore germination is increased. alaynecuzick 2018-10-03T13:38:33Z increased conidia germination frequency single_species_phenotype increased asexual spore germination frequency PHIPO:0000275 A phenotype that shows detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney). alaynecuzick 2018-10-03T13:39:04Z single_species_phenotype abnormal tissue phenotype PHIPO:0000276 A phenotype that does not show any detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney). alaynecuzick 2018-10-03T13:39:23Z single_species_phenotype normal tissue phenotype PHIPO:0000277 alaynecuzick 2018-10-03T13:39:41Z single_species_phenotype obsolete abnormal filamentous growth true PHIPO:0000279 alaynecuzick 2018-10-03T13:43:37Z pathogen_host_interaction_phenotype obsolete systemic phenotype true PHIPO:0000280 A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to activate or suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. alaynecuzick 2018-10-05T11:00:39Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate To annotate a metagenotype containing a pathogen effector use 'GO:0140418 effector-mediated modulation of host process by symbiont' or a descendant. This is only to be used when there is manipulation of the host. pathogen effector mediated modulation of host immune system process PHIPO:0000281 alaynecuzick 2018-10-05T12:33:43Z single_species_phenotype obsolete stature phenotype true PHIPO:0000282 alaynecuzick 2018-10-05T12:33:56Z single_species_phenotype obsolete abnormal stature true PHIPO:0000283 alaynecuzick 2018-10-05T12:34:05Z single_species_phenotype obsolete normal stature true PHIPO:0000284 A single species individual organism phenotype affecting the deposition or aggregation of coloring matter in a cell. alaynecuzick 2018-10-05T12:37:03Z single_species_phenotype pigment phenotype PHIPO:0000285 A single species individual organism phenotype where the accumulation of coloring matter in a cell is abnormal. alaynecuzick 2018-10-05T12:37:16Z single_species_phenotype abnormal cellular pigment accumulation PHIPO:0000286 A single species individual organism phenotype where the accumulation of coloring matter in a cell is normal. alaynecuzick 2018-10-05T12:37:24Z single_species_phenotype normal cellular pigment accumulation PHIPO:0000287 A single species individual organism phenotype where the accumulation of coloring matter in a cell is increased. alaynecuzick 2018-10-05T12:38:26Z single_species_phenotype increased cellular pigment accumulation PHIPO:0000288 A single species individual organism phenotype where the accumulation of coloring matter in a cell is decreased. alaynecuzick 2018-10-05T12:38:39Z single_species_phenotype decreased cellular pigment accumulation PHIPO:0000289 alaynecuzick 2018-10-05T12:38:58Z single_species_phenotype host_phenotype obsolete altered colour true PHIPO:0000290 alaynecuzick 2018-10-05T12:39:18Z single_species_phenotype host_phenotype obsolete colour present true PHIPO:0000291 alaynecuzick 2018-10-05T12:39:26Z single_species_phenotype obsolete colour absent true PHIPO:0000292 A single species cell morphology phenotype where hyphal filaments are short in length. alaynecuzick 2018-10-05T12:43:16Z reduced filament length single_species_phenotype decreased filament length PHIPO:0000293 alaynecuzick 2018-10-05T12:48:26Z single_species_phenotype obsolete abnormal organism morphology phenotype true PHIPO:0000294 alaynecuzick 2018-10-05T12:52:54Z single_species_phenotype obsolete normal organism morphology phenotype true PHIPO:0000295 A single species cell morphology phenotype where hyphal filaments are wavy. alaynecuzick 2018-10-05T12:53:20Z wavy hyphae single_species_phenotype sinusoidal filament PHIPO:0000296 alaynecuzick 2018-10-05T12:56:56Z single_species_phenotype obsolete normal dissemination of pathogen asexual product true PHIPO:0000297 alaynecuzick 2018-10-05T12:57:37Z single_species_phenotype obsolete normal dissemination of pathogen sexual product true PHIPO:0000298 alaynecuzick 2018-10-05T12:58:29Z single_species_phenotype obsolete abnormal dissemination of pathogen asexual product true PHIPO:0000299 alaynecuzick 2018-10-05T12:58:58Z single_species_phenotype obsolete abnormal dissemination of pathogen sexual product true PHIPO:0000300 A single species phenotype where the dispersal of asexual spores is abnormal (FAO:0000023). alaynecuzick 2018-10-05T13:00:13Z abnormal dissemination of conidia single_species_phenotype abnormal dissemination of asexual spore PHIPO:0000301 A single species phenotype where the dispersal of asexual spores is normal (FAO:0000023). alaynecuzick 2018-10-05T13:00:21Z normal dissemination of conidia single_species_phenotype normal dissemination of asexual spore PHIPO:0000302 A single species phenotype where the dispersal of sexual spores is normal (FAO:0000017). alaynecuzick 2018-10-05T13:00:34Z single_species_phenotype normal dissemination of sexual spore PHIPO:0000303 A single species phenotype where the dispersal of sexual spores is abnormal (FAO:0000017). alaynecuzick 2018-10-05T13:00:37Z single_species_phenotype abnormal dissemination of sexual spore PHIPO:0000305 (Required for successful infection of the host species). The ability of an organism to activate or suppress host defenses to enable infectious disease. (Irrespective of the host genotype). alaynecuzick 2018-10-18T12:55:58Z pathogen_host_interaction_phenotype obsolete effector of pathogenicity phenotype true PHIPO:0000306 The host defenses activated by the pathogen are altered compared to the wild type interaction alaynecuzick 2018-10-18T12:56:08Z pathogen_host_interaction_phenotype obsolete abnormal effector of virulence true PHIPO:0000307 The ability to cause disease by activating or suppressing host defenses is unaltered compared to the wildtype interaction. This may result in the outcome of being pathogenic or not-pathogenic. alaynecuzick 2018-10-18T12:58:41Z pathogen_host_interaction_phenotype obsolete normal effector of pathogenicity true PHIPO:0000308 The host defenses activated by the pathogen are unaltered compared to the wild type interaction alaynecuzick 2018-10-18T12:59:50Z pathogen_host_interaction_phenotype obsolete normal effector of pathogenicity activation of host defense true PHIPO:0000309 The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction alaynecuzick 2018-10-18T13:11:15Z pathogen_host_interaction_phenotype obsolete normal effector of pathogenicity suppression of host defense true PHIPO:0000310 The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is unaltered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence). alaynecuzick 2018-10-18T13:12:40Z pathogen_host_interaction_phenotype obsolete normal effector of virulence true PHIPO:0000311 (gene for gene relationships) or defined from the phenotype described in the published study. The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype. alaynecuzick 2018-10-18T13:14:06Z pathogen_host_interaction_phenotype obsolete effector of virulence phenotype true PHIPO:0000312 The ability to cause disease by activating or suppressing host defenses is altered compared to the wildtype interaction. alaynecuzick 2018-10-18T13:15:10Z pathogen_host_interaction_phenotype obsolete abnormal effector of pathogenicity true PHIPO:0000313 The host defenses activated by the pathogen are unaltered compared to the wild type interaction alaynecuzick 2018-10-18T13:22:08Z pathogen_host_interaction_phenotype obsolete normal effector of virulence activation of host defense true PHIPO:0000314 The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction alaynecuzick 2018-10-18T13:22:20Z pathogen_host_interaction_phenotype obsolete normal effector of virulence suppression of host defense true PHIPO:0000315 The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is altered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence). alaynecuzick 2018-10-18T13:25:51Z pathogen_host_interaction_phenotype obsolete abnormal effector of virulence activation of host defense true PHIPO:0000316 The pathogen effector entity has a decreased ability to activate host defense. alaynecuzick 2018-10-18T13:26:40Z pathogen_host_interaction_phenotype obsolete decreased effector of virulence activation of host defense true PHIPO:0000317 The pathogen effector entity has an increased ability to activate host defense. alaynecuzick 2018-10-18T13:27:34Z pathogen_host_interaction_phenotype obsolete increased effector of virulence activation of host defense true PHIPO:0000318 The host defenses suppressed by the pathogen are altered compare to the wild type interaction alaynecuzick 2018-10-18T13:28:11Z pathogen_host_interaction_phenotype obsolete abnormal effector of virulence suppression of host defense true PHIPO:0000319 The pathogen effector entity has a decreased ability to suppress host defense. alaynecuzick 2018-10-18T13:28:53Z pathogen_host_interaction_phenotype obsolete decreased effector of virulence suppression of host defense true PHIPO:0000320 The pathogen effector entity has an increased ability to suppress host defense. alaynecuzick 2018-10-18T13:29:31Z pathogen_host_interaction_phenotype obsolete increased effector of virulence suppression of host defense true PHIPO:0000321 The host defenses activated by the pathogen are altered compared to the wild type interaction. alaynecuzick 2018-10-18T13:31:28Z pathogen_host_interaction_phenotype obsolete abnormal effector of pathogenicity activation of host defense true PHIPO:0000322 The pathogen effector entity has gained the ability to activate host defense. alaynecuzick 2018-10-18T13:32:29Z pathogen_host_interaction_phenotype obsolete gain of effector of pathogenicity activation of host defense true PHIPO:0000323 The pathogen effector entity has lost the ability to activate host defense. alaynecuzick 2018-10-18T13:32:51Z pathogen_host_interaction_phenotype obsolete loss of effector of pathogenicity activation of host defense true PHIPO:0000324 The host defenses suppressed by the pathogen are altered compared to the wild type interaction alaynecuzick 2018-10-18T13:33:53Z pathogen_host_interaction_phenotype obsolete abnormal effector of pathogenicity suppression of host defense true PHIPO:0000325 The pathogen effector entity has gained the ability to suppress host defense. alaynecuzick 2018-10-18T13:34:13Z pathogen_host_interaction_phenotype obsolete gain of effector of pathogenicity suppression of host defense true PHIPO:0000326 The pathogen effector entity has lost the ability to suppress host defense. alaynecuzick 2018-10-18T13:34:33Z pathogen_host_interaction_phenotype obsolete loss of effector of pathogenicity suppression of host defense true PHIPO:0000327 A growth phenotype which describes the resistance of individuals or populations after exposure to cypronazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-10-19T13:41:59Z single_species_phenotype resistance to cyproconazole PHIPO:0000328 A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-10-19T13:42:19Z FYPO:0006003 single_species_phenotype normal cellular component organization PHIPO:0000329 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyproconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-10-19T13:42:46Z single_species_phenotype sensitive to cyproconazole PHIPO:0000330 A molecular function phenotype in which the observed rate of a specified transporter activity is abnormal. alaynecuzick 2018-10-19T13:43:13Z FYPO:0002116 single_species_phenotype abnormal transporter activity PHIPO:0000331 A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is present. alaynecuzick 2018-10-29T15:59:22Z pathogen_host_interaction_phenotype pathogen invasion of host present pathogen penetration into host present PHIPO:0000332 A pathogen host interaction phenotype which affects the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2018-10-29T16:06:31Z pathogen_host_interaction_phenotype Colonization of host is the action of a pathogen establishing itself in a host. (Covers adhesion, penetration, surface growth). pathogen colonization of host phenotype PHIPO:0000333 A pathogen host interaction colonization phenotype which affects the directional movement of the pathogen within the host organism (GO:0044001). alaynecuzick 2018-10-29T16:08:18Z pathogen_host_interaction_phenotype pathogen cell to cell migration within host phenotype PHIPO:0000334 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is abnormal. alaynecuzick 2018-10-29T16:09:56Z pathogen_host_interaction_phenotype abnormal pathogen cell to cell migration within host PHIPO:0000335 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is normal. alaynecuzick 2018-10-29T16:10:17Z pathogen_host_interaction_phenotype normal pathogen cell to cell migration within host PHIPO:0000336 alaynecuzick 2018-10-29T16:16:46Z pathogen_host_interaction_phenotype obsolete intracellular growth phenotype true PHIPO:0000337 alaynecuzick 2018-10-29T16:17:02Z pathogen_host_interaction_phenotype obsolete extracellular growth phenotype true PHIPO:0000338 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is increased compared to normal. alaynecuzick 2018-10-29T16:17:55Z pathogen_host_interaction_phenotype increased pathogen cell to cell migration within host PHIPO:0000339 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is decreased compared to normal. alaynecuzick 2018-10-29T16:18:09Z pathogen_host_interaction_phenotype decreased pathogen cell to cell migration within host PHIPO:0000340 A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is abolished (pathogen migration was present within the host and is now absent). alaynecuzick 2018-10-29T16:18:22Z pathogen_host_interaction_phenotype abolished pathogen cell to cell migration within host PHIPO:0000341 A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is gained (pathogen migration was absent within the host and is now present). alaynecuzick 2018-10-29T16:18:44Z pathogen_host_interaction_phenotype obsolete gain of pathogen cell to cell migration within host true PHIPO:0000342 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens sooner than normal. alaynecuzick 2018-10-29T16:19:03Z pathogen_host_interaction_phenotype premature pathogen cell to cell migration within host PHIPO:0000343 A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens later than normal. alaynecuzick 2018-10-29T16:19:20Z pathogen_host_interaction_phenotype delayed pathogen cell to cell migration within host PHIPO:0000344 alaynecuzick 2018-10-29T16:23:29Z pathogen_host_interaction_phenotype obsolete normal pathogen host interaction molecular function true PHIPO:0000345 alaynecuzick 2018-10-29T16:32:47Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction molecular function true PHIPO:0000346 alaynecuzick 2018-10-29T16:33:27Z pathogen_host_interaction_phenotype obsolete host necrotic lesion with pathogen phenotype true PHIPO:0000347 A pathogen host interaction phenotype that affects a molecular function such as binding or catalytic activity. alaynecuzick 2018-10-29T16:34:09Z pathogen_host_interaction_phenotype pathogen host interaction molecular function phenotype PHIPO:0000348 A pathogen host interaction phenotype which affects a catalytic activity. alaynecuzick 2018-10-29T17:04:57Z pathogen_host_interaction_phenotype obsolete pathogen host interaction catalytic activity phenotype true PHIPO:0000349 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is present. alaynecuzick 2018-11-05T13:23:08Z pathogen growth present on host surface pathogen_host_interaction_phenotype presence of pathogen growth on host surface PHIPO:0000350 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is absent. alaynecuzick 2018-11-05T13:23:33Z pathogen growth absent on host surface pathogen_host_interaction_phenotype absence of pathogen growth on host surface PHIPO:0000351 A pathogen growth with host phenotype in which the pathogen is able to penetrate the host. alaynecuzick 2018-11-05T13:24:13Z pathogen_host_interaction_phenotype obsolete pathogen is able to penetrate host true PHIPO:0000352 A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is normal (i.e indistinguishable from wild type). alaynecuzick 2018-11-05T13:24:42Z normal formation of pathogen infection structure prior to entry into host normal pre penetration of host by pathogen pathogen_host_interaction_phenotype normal formation of pathogen penetration structure prior to entry into host PHIPO:0000353 A pathogen growth with host phenotype in which the pathogen penetration into the host is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-11-05T13:25:01Z normal pathogen entry into host pathogen_host_interaction_phenotype obsolete normal penetration of host by pathogen true PHIPO:0000355 A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is absent. alaynecuzick 2018-11-05T13:26:18Z PHIPO:0000357 abolished pathogen entry into host pathogen_host_interaction_phenotype abolished pathogen penetration into host pathogen invasion of host absent pathogen penetration into host absent PHIPO:0000356 A pathogen growth with host phenotype in which the pathogen penetration into the host is abnormal (i.e different than wild-type). alaynecuzick 2018-11-05T13:26:35Z abnormal pathogen entry into host phenotype pathogen_host_interaction_phenotype obsolete abnormal penetration of host by pathogen true PHIPO:0000358 A pathogen growth with host phenotype in which the pathogen forms a non-functional specialized penetration structure. alaynecuzick 2018-11-05T13:30:29Z pathogen_host_interaction_phenotype obsolete non-functional pathogen penetration structure in contact with host true PHIPO:0000359 A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is decreased. alaynecuzick 2018-11-05T13:31:26Z decreased pathogen entry into host pathogen_host_interaction_phenotype decreased pathogen invasion of host decreased pathogen penetration into host PHIPO:0000360 A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is increased. alaynecuzick 2018-11-05T13:32:32Z increased pathogen entry into host pathogen_host_interaction_phenotype increased pathogen invasion of host increased pathogen penetration into host PHIPO:0000361 A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins later than normal. alaynecuzick 2018-11-05T13:32:57Z delayed pathogen entry into host pathogen_host_interaction_phenotype delayed pathogen invasion of host delayed pathogen penetration into host PHIPO:0000362 A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins sooner than normal. alaynecuzick 2018-11-05T13:33:34Z premature pathogen entry into host pathogen_host_interaction_phenotype premature pathogen invasion of host premature pathogen penetration into host PHIPO:0000363 A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is absent. alaynecuzick 2018-11-05T13:35:05Z absent pathogen growth within host pathogen_host_interaction_phenotype absence of pathogen growth within host PHIPO:0000364 A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abnormal (i.e different than wild type). alaynecuzick 2018-11-05T13:37:31Z pathogen_host_interaction_phenotype obsolete abnormal pathogen growth within host true PHIPO:0000365 A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is decreased. alaynecuzick 2018-11-05T13:39:00Z decreased branching of invasive hyphae in host decreased number of invasive hyphae in host pathogen_host_interaction_phenotype reduced pathogen biomass within host tissue decreased pathogen growth within host PHIPO:0000366 A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins later than normal. alaynecuzick 2018-11-05T13:39:34Z pathogen_host_interaction_phenotype delayed timing of pathogen growth within host PHIPO:0000367 A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins sooner than normal. alaynecuzick 2018-11-05T13:40:14Z pathogen_host_interaction_phenotype premature pathogen growth within host PHIPO:0000368 A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is increased. alaynecuzick 2018-11-05T13:41:05Z pathogen_host_interaction_phenotype increased pathogen biomass within host tissue increased pathogen growth within host PHIPO:0000369 A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type). alaynecuzick 2018-11-08T12:12:18Z abnormal formation of pathogen infection structure when near host abnormal pre penetration pathogen_host_interaction_phenotype abnormal formation of pathogen penetration structure when near host PHIPO:0000370 A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is absent. alaynecuzick 2018-11-08T12:14:10Z pathogen_host_interaction_phenotype obsolete pathogen penetration structure absent when near host true PHIPO:0000371 A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are decreased. alaynecuzick 2018-11-08T12:15:52Z decreased number of pathogen infection structure when near host pathogen_host_interaction_phenotype decreased number of pathogen penetration structure when near host PHIPO:0000372 A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are decreased. alaynecuzick 2018-11-08T12:16:29Z decreased size of pathogen infection structure when near host pathogen_host_interaction_phenotype decreased size of pathogen penetration structure when near host PHIPO:0000373 A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are increased. alaynecuzick 2018-11-08T12:16:46Z increased number of pathogen infection structure when near host pathogen_host_interaction_phenotype increased number of pathogen penetration structure when near host PHIPO:0000374 A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are increased. alaynecuzick 2018-11-08T12:17:03Z increased size of pathogen infection structure when near host pathogen_host_interaction_phenotype increased size of pathogen penetration structure when near host PHIPO:0000375 A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins later than normal. alaynecuzick 2018-11-08T12:17:35Z delayed timing of pathogen infection structure formation when near host pathogen_host_interaction_phenotype delayed timing of pathogen penetration structure formation when near host PHIPO:0000376 A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins sooner than normal. alaynecuzick 2018-11-08T12:17:52Z premature pathogen infection structure formation when near host pathogen_host_interaction_phenotype premature pathogen penetration structure formation when near host PHIPO:0000377 A growth phenotype which describes the resistance of individuals or populations after exposure to carboxin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:32:23Z single_species_phenotype resistance to carboxin PHIPO:0000378 A growth phenotype which describes the sensitivity of individuals or populations after exposure to carboxin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:33:05Z single_species_phenotype sensitive to carboxin PHIPO:0000379 A cellular process phenotype in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. alaynecuzick 2018-12-05T11:33:32Z FYPO:0004805 single_species_phenotype abnormal cell wall organization PHIPO:0000380 A molecular function phenotype in which the observed rate of a specified transporter activity is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-05T11:33:53Z FYPO:0002115 single_species_phenotype normal transporter activity PHIPO:0000381 A growth phenotype which describes the resistance of individuals or populations after exposure to benomyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:34:42Z single_species_phenotype resistance to benomyl PHIPO:0000382 A growth phenotype which describes the resistance of individuals or populations after exposure to diethofencarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:35:13Z single_species_phenotype resistance to diethofencarb PHIPO:0000383 A growth phenotype which describes the resistance of individuals or populations after exposure to carbendazim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:35:34Z single_species_phenotype resistance to carbendazim PHIPO:0000384 A growth phenotype which describes the resistance of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:35:57Z single_species_phenotype resistance to thiophanate methyl PHIPO:0000385 A growth phenotype which describes the resistance of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:36:23Z single_species_phenotype resistance to oxolinic acid PHIPO:0000386 A growth phenotype which describes the resistance of individuals or populations after exposure to naftifine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:37:06Z single_species_phenotype resistance to naftifine PHIPO:0000387 A growth phenotype which describes the resistance of individuals or populations after exposure to terbinafine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:37:20Z single_species_phenotype resistance to terbinafine PHIPO:0000388 A growth phenotype which describes the resistance of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:37:46Z single_species_phenotype resistance to azoxystrobin PHIPO:0000389 A growth phenotype which describes the resistance of individuals or populations after exposure to iprodione. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:38:07Z single_species_phenotype resistance to iprodione PHIPO:0000390 A growth phenotype which describes the sensitivity of individuals or populations after exposure to diethocarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:39:03Z single_species_phenotype sensitive to diethofencarb PHIPO:0000391 A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbendazim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:39:31Z single_species_phenotype sensitive to carbendazim PHIPO:0000392 A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:39:58Z single_species_phenotype sensitive to thiophanate methyl PHIPO:0000393 A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:40:15Z single_species_phenotype sensitive to oxolinic acid PHIPO:0000394 A growth phenotype which describes the sensitivity of individuals or populations after exposure to naftifine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:40:34Z single_species_phenotype sensitive to naftifine PHIPO:0000395 A growth phenotype which describes the sensitivity of individuals or populations after exposure to terbinafine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:40:53Z single_species_phenotype sensitive to terbinafine PHIPO:0000396 A growth phenotype which describes the sensitivity of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:41:17Z single_species_phenotype sensitive to azoxystrobin PHIPO:0000397 A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprodione. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:41:35Z single_species_phenotype sensitive to iprodione PHIPO:0000398 A growth phenotype which describes the sensitivity of individuals or populations after exposure to benomyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-12-05T11:42:11Z single_species_phenotype sensitive to benomyl PHIPO:0000399 alaynecuzick 2018-12-05T11:43:18Z single_species_phenotype obsolete abnormal phialide morphology true PHIPO:0000400 A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal. alaynecuzick 2018-12-05T11:43:39Z FYPO:0000335 single_species_phenotype abnormal cellular component organization PHIPO:0000401 alaynecuzick 2018-12-05T11:43:53Z single_species_phenotype obsolete normal phialide morphology true PHIPO:0000402 A single species phenotype that is observed at the level of an individual organism. alaynecuzick 2018-12-05T11:44:12Z single_species_phenotype individual organism phenotype PHIPO:0000403 A phenotype that does not show any detectable differences from normal at the level of an individual cell. alaynecuzick 2018-12-05T11:44:26Z single_species_phenotype normal cell phenotype PHIPO:0000404 A phenotype that shows detectable differences from normal at the level of an individual cell. alaynecuzick 2018-12-05T11:44:40Z FYPO:0003037 single_species_phenotype abnormal cell phenotype PHIPO:0000405 A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-05T11:44:58Z PHIPO:0000123 single_species_phenotype normal population growth during dimorphic yeast-form normal unicellular population growth PHIPO:0000406 A single organism phenotype in which the nucleus is absent. alaynecuzick 2018-12-05T11:45:18Z single_species_phenotype nucleus absent PHIPO:0000407 A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level. alaynecuzick 2018-12-05T11:45:32Z FYPO:0000334 cellular component organisation phenotype single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. cellular component organization phenotype PHIPO:0000408 alaynecuzick 2018-12-05T11:46:07Z single_species_phenotype obsolete morphology phenotype true PHIPO:0000409 A phenotype that affects a transporter activity. alaynecuzick 2018-12-05T11:46:27Z FYPO:0002114 single_species_phenotype transporter activity phenotype PHIPO:0000410 A population phenotype in which the frequency of occurrence of asexual spore germination is decreased. alaynecuzick 2018-12-05T11:46:43Z decreased conidia germination frequency single_species_phenotype decreased asexual spore germination frequency PHIPO:0000411 A phenotype that affects a molecular function such as binding or catalytic activity. alaynecuzick 2018-12-05T11:46:59Z single_species_phenotype molecular function phenotype PHIPO:0000413 A phenotype in which a specific molecular function is abnormal. alaynecuzick 2018-12-05T11:47:25Z FYPO:0000707 single_species_phenotype abnormal molecular function PHIPO:0000414 A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser or greater than normal. alaynecuzick 2018-12-05T11:47:39Z PHIPO:0000163 single_species_phenotype abnormal population growth during dimorphic yeast-form abnormal unicellular population growth PHIPO:0000415 A single organism phenotype in which the amount, distribution, composition or morphology of a cell part is abnormal. alaynecuzick 2018-12-05T11:47:55Z FYPO:0000287 single_species_phenotype abnormal subcellular component PHIPO:0000416 A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-05T11:48:08Z FYPO:0000706 single_species_phenotype normal molecular function PHIPO:0000417 alaynecuzick 2018-12-10T14:12:15Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction pathogen carbohydrate binding phenotype true PHIPO:0000418 A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:12:55Z single_species_phenotype normal carbohydrate binding PHIPO:0000419 A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:13:02Z single_species_phenotype abnormal carbohydrate binding PHIPO:0000420 A single species molecular function phenotype in which occurrence of pathogen chitin fragment binding by a pathogen gene product is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-10T14:14:16Z single_species_phenotype normal pathogen chitin fragment binding PHIPO:0000421 A single species molecular function phenotype in which carbohydrate binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:16:24Z single_species_phenotype abolished carbohydrate binding PHIPO:0000422 A single species phenotype in which a gene product that normally binds to a specific carbohydrate instead binds to a different carbohydrate when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:17:21Z single_species_phenotype no logical definition for 'altered ? binding specificity' in FYPO altered carbohydrate binding specificity PHIPO:0000423 A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:17:46Z single_species_phenotype decreased carbohydrate binding PHIPO:0000424 A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:18:04Z single_species_phenotype increased carbohydrate binding PHIPO:0000425 A pathogen host interaction phenotype which affects the binding of carbohydrate to protein. alaynecuzick 2018-12-10T14:23:58Z pathogen_host_interaction_phenotype obsolete pathogen host interaction pathogen carbohydrate binding phenotype true PHIPO:0000426 A molecular function phenotype in which the binding of pathogen chitinase to pathogen chitin fragments generated within a host interaction is present. alaynecuzick 2018-12-10T14:30:09Z pathogen_host_interaction_phenotype obsolete presence of pathogen chitinase binding to pathogen chitin fragments within host interaction true PHIPO:0000427 A molecular function phenotype in which the binding of pathogen chitin to host chitinase is present. alaynecuzick 2018-12-10T14:31:18Z pathogen_host_interaction_phenotype obsolete pathogen chitin binding to host chitinase present true PHIPO:0000428 alaynecuzick 2018-12-10T14:32:15Z pathogen_host_interaction_phenotype obsolete normal pathogen host interaction pathogen carbohydrate binding phenotype true PHIPO:0000429 alaynecuzick 2018-12-10T14:32:50Z pathogen_host_interaction_phenotype obsolete normal pathogen and host chitinases bind pathogen chitin and chitin fragments true PHIPO:0000430 A single species molecular function phenotype that affects carbohydrate binding. The affected gene product may be encoded by the mutated gene, or by a different gene. alaynecuzick 2018-12-10T14:37:34Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. carbohydrate binding phenotype PHIPO:0000431 A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product does not occur. (It was present and is now absent). alaynecuzick 2018-12-10T14:39:51Z single_species_phenotype abolished pathogen chitin fragment binding PHIPO:0000432 A single organism phenotype that affects a catalytic activity. alaynecuzick 2018-12-11T13:52:59Z FYPO:0000654 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. catalytic activity phenotype PHIPO:0000433 A single species molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-11T13:54:41Z FYPO:0000660 single_species_phenotype normal catalytic activity PHIPO:0000434 A single species molecular function phenotype in which the observed rate or other catalytic property of a specified catalytic activity is abnormal. alaynecuzick 2018-12-11T13:55:08Z FYPO:0000661 single_species_phenotype abnormal catalytic activity PHIPO:0000435 A single species molecular function phenotype in which a specified catalytic activity is absent. alaynecuzick 2018-12-12T14:40:37Z FYPO:0000664 catalytic activity abolished catalytic activity absent single_species_phenotype abolished catalytic activity PHIPO:0000436 A single species molecular function phenotype in which the observed rate of a specified catalytic activity is decreased. alaynecuzick 2018-12-12T14:40:59Z FYPO:0000663 single_species_phenotype decreased catalytic activity PHIPO:0000437 A single species molecular function phenotype in which the observed rate of a specified catalytic activity is increased. alaynecuzick 2018-12-12T14:41:15Z PHIPO:0001082 FYPO:0000662 single_species_phenotype gain of catalytic activity increased catalytic activity PHIPO:0000438 A single species molecular function phenotype in which the substrate specificity of a catalytic activity differs from wild type. alaynecuzick 2018-12-12T14:41:30Z FYPO:0003347 single_species_phenotype no FYPO logical defintion for 'altered substrate specificity' altered substrate specificity PHIPO:0000439 A pathogen host interaction phenotype which affects the pathogen reproductive process within the host. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). alaynecuzick 2018-12-18T11:25:46Z pathogen_host_interaction_phenotype pathogen reproductive phenotype within host PHIPO:0000440 A pathogen host interaction phenotype where the pathogen reproductive process within the host is normal (indistinguishable from wild type). alaynecuzick 2018-12-18T11:26:40Z pathogen_host_interaction_phenotype normal pathogen reproductive phenotype within host PHIPO:0000441 A pathogen host interaction phenotype where the pathogen reproductive process within the host is abnormal. alaynecuzick 2018-12-18T11:26:59Z pathogen_host_interaction_phenotype abnormal pathogen reproductive phenotype within host PHIPO:0000442 A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954). alaynecuzick 2018-12-18T11:27:55Z pathogen_host_interaction_phenotype normal pathogen asexual reproduction within host PHIPO:0000443 A pathogen reproductive phenotype within host where the pathogen sexual reproduction process, in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953). alaynecuzick 2018-12-18T11:28:13Z pathogen_host_interaction_phenotype normal pathogen sexual reproduction within host PHIPO:0000444 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is decreased. alaynecuzick 2018-12-18T11:34:08Z decreased number of pathogen conidia within host decreased number of pathogen uredinia within host pathogen_host_interaction_phenotype decreased number of asexual pathogen spores within host PHIPO:0000445 A phenotype that affects the process of host tissue death causing a host lesion induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. alaynecuzick 2018-12-18T12:46:14Z host necrotic lesion with pathogen phenotype pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen host interaction host lesion formation phenotype PHIPO:0000446 A single species phenotype that affects the cell death within a host. alaynecuzick 2018-12-18T12:46:45Z single_species_phenotype host_phenotype host cell death phenotype PHIPO:0000447 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is increased. alaynecuzick 2018-12-18T13:53:43Z increased number of pathogen conidia within host increased number of pathogen uredinia within host pathogen_host_interaction_phenotype increased number of asexual pathogen spores within host PHIPO:0000448 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is abnormal alaynecuzick 2018-12-18T14:43:36Z abnormal number of pathogen conidia within host pathogen_host_interaction_phenotype abnormal number of asexual pathogen spores within host PHIPO:0000449 A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954). alaynecuzick 2018-12-18T14:44:36Z pathogen_host_interaction_phenotype abnormal pathogen asexual reproduction within host PHIPO:0000450 A single species molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type). alaynecuzick 2018-12-19T09:51:47Z FYPO:0000665 normal protease activity single_species_phenotype normal pathogen peptidase activity PHIPO:0000461 A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own programmed cell death pathways in defense, is present. alaynecuzick 2018-12-21T12:55:04Z pathogen_host_interaction_phenotype host necrotic cell death host programmed cell death phenotype induced by pathogen presence presence of host lesion Note that if you are curating a necrotroph you need to annotate to PHIPO:0000477. presence of pathogen-associated host defense induced lesions PHIPO:0000463 A single organism phenotype that affects the subcellular components in a cell. alaynecuzick 2018-12-21T12:56:41Z single_species_phenotype subcellular component phenotype PHIPO:0000464 A phenotype affecting the process of host tissue cell death caused by the pathogen (GO:0097300 part of GO:0009608 ). alaynecuzick 2018-12-21T13:01:44Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete host necrotic cell death phenotype in response to pathogen true PHIPO:0000465 A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is absent. alaynecuzick 2018-12-21T12:55:59Z PHIPO:0000462 pathogen_host_interaction_phenotype abolished effector-mediated host programmed cell death during necrotrophy abolished host lesion abolished host necrotic cell death absence of effector-mediated host programmed cell death during necrotrophy absence of host lesion absence of host necrotic cell death This term is to be used when the pathogen actively induces the host responses, not for host protection against the pathogen. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. absence of pathogen necrotrophic effector-mediated host programmed cell death PHIPO:0000466 A phenotype that affects the immune system process of host necrotic cell death by pathogen induced hypersensitive response. Pathogen induced hypersensitive response is the rapid, localized death of plant cells in response to invasion by a pathogen (GO:0009626). alaynecuzick 2018-12-21T13:09:35Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This term is to be used for host protection against the pathogen. This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete host necrotic cell death by pathogen induced hypersensitive response true PHIPO:0000467 A single species phenotype where the immune system process of host tissue hypersensitive response is present in a pathogen effector-independant manner. (i.e. an alteration within the host is responsible for the activation of the hypersensitive response in the absence of a pathogen). alaynecuzick 2018-12-21T13:24:37Z single_species_phenotype host_phenotype presence of effector-independent host hypersensitive response PHIPO:0000468 A pathogen reproductive phenotype within host where the pathogen asexual spores are absent (FAO:0000023). alaynecuzick 2019-01-11T10:31:18Z pathogen conidia absent within host pathogen uredinia absent within host pathogen_host_interaction_phenotype absence of pathogen asexual spores within host PHIPO:0000469 A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436). alaynecuzick 2019-01-11T10:32:18Z pathogen_host_interaction_phenotype abnormal pathogen asexual sporulation within host PHIPO:0000470 alaynecuzick 2019-01-11T10:40:06Z pathogen_host_interaction_phenotype obsolete location of pathogen growth within host phenotype true PHIPO:0000472 A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436). alaynecuzick 2019-01-11T11:49:51Z pathogen_host_interaction_phenotype normal pathogen asexual sporulation within host PHIPO:0000473 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-01-11T11:55:09Z normal number of pathogen conidia within host normal number of pathogen uredinia within host pathogen_host_interaction_phenotype presence of pathogen asexual spores within host PHIPO:0000474 A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain a different number of lipid droplets than normal. alaynecuzick 2019-01-14T12:21:01Z single_species_phenotype abnormal number of lipid droplets PHIPO:0000475 A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is decreased. alaynecuzick 2019-01-14T12:21:13Z single_species_phenotype decreased size of lipid droplet PHIPO:0000477 A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is present. alaynecuzick 2019-01-14T12:22:36Z PHIPO:0000476 pathogen_host_interaction_phenotype gain of effector-mediated host programmed cell death during necrotrophy gain of host necrotic cell death gain of presence of host lesion presence of effector-mediated host programmed cell death during necrotrophy presence of host lesion presence of host necrotic cell death This term is to be used when the pathogen actively induces the host responses, not for host protection against the pathogen. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. presence of pathogen necrotrophic effector-mediated host programmed cell death PHIPO:0000478 A single organism phenotype that affects an intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. alaynecuzick 2019-01-14T12:23:44Z GO:0005811 single_species_phenotype lipid droplet phenotype PHIPO:0000479 A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is increased. alaynecuzick 2019-01-14T12:23:54Z single_species_phenotype increased size of lipid droplet PHIPO:0000480 A phenotype where the process of host tissue cell death causing a host lesion is present. alaynecuzick 2019-01-14T12:24:50Z normal host lesion formation with pathogen pathogen_host_interaction_phenotype presence of host necrotic cell death by pathogen The lesion can be induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. presence of pathogen-associated host lesions PHIPO:0000481 A phenotype where the process of host tissue cell death causing a host lesion is absent. alaynecuzick 2019-08-10T13:35:33Z PHIPO:0000997 pathogen_host_interaction_phenotype abolished pathogen-associated host lesions absence of host necrotic cell death by pathogen The lesion can be induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. Note that if you are curating a necrotroph you need to annotate to PHIPO:0000465. absence of pathogen-associated host lesions PHIPO:0000483 A pathogen host interaction phenotype which is normal (i.e. the same as wild-type). alaynecuzick 2019-01-14T13:59:00Z pathogen_host_interaction_phenotype obsolete normal pathogen host interaction phenotype true PHIPO:0000484 A pathogen host interaction phenotype which is abnormal (i.e. different than wild-type). alaynecuzick 2019-01-14T13:59:26Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction phenotype true PHIPO:0000492 A single organism phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. alaynecuzick 2019-01-18T12:52:27Z GO_0008152 single_species_phenotype Definition adapted from GO_0008152 metabolic process metabolic process phenotype PHIPO:0000493 A single organism phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. alaynecuzick 2019-01-18T12:55:03Z GO:0044238 single_species_phenotype Definition adapted from GO:0044238 primary metabolic process primary metabolic process phenotype PHIPO:0000494 A single organism phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. alaynecuzick 2019-01-18T12:55:20Z GO:0019748 single_species_phenotype Definition adapted from GO:0019748 secondary metabolic process secondary metabolic process phenotype PHIPO:0000495 A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. alaynecuzick 2019-01-18T13:02:07Z GO:0044550 single_species_phenotype Definition adapted from GO:0044550 secondary metabolite biosynthetic process secondary metabolite biosynthetic process phenotype PHIPO:0000496 A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. alaynecuzick 2019-01-18T13:04:12Z GO:0009403 single_species_phenotype Definition adapted fromo GO:0009403 toxin biosynthetic process toxin biosynthetic process phenotype PHIPO:0000497 A single organism phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type). alaynecuzick 2019-01-18T13:04:39Z single_species_phenotype normal toxin biosynthetic process PHIPO:0000498 A single organism phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type). alaynecuzick 2019-01-18T13:04:53Z single_species_phenotype For logical defintions Do we want to make this species neutral and just add in DON at lowest child level and use CHEBI id CHEBI_10022 ## vomitoxin OR use fungi specific GO term GO_0106110 ## vomitoxin biosynthetic process?? abnormal toxin biosynthetic process PHIPO:0000499 A single organism phenotype in which the biosynthesis of deoxynivalenol is normal (i.e. same as the wild type). alaynecuzick 2019-01-18T13:05:54Z single_species_phenotype obsolete normal synthesis of deoxynivalenol true PHIPO:0000500 A single organism phenotype in which the biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type). alaynecuzick 2019-01-18T13:06:19Z single_species_phenotype obsolete abnormal biosynthesis of deoxynivalenol true PHIPO:0000501 A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is higher than normal. alaynecuzick 2019-01-18T13:06:49Z single_species_phenotype obsolete increased level of deoxynivalenol true PHIPO:0000502 A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is lower than normal. alaynecuzick 2019-01-18T13:07:24Z single_species_phenotype obsolete decreased level of deoxynivalenol true PHIPO:0000503 A single organism cell phenotype in which the amount of deoxynivalenol measured in a cell is too low to detect. alaynecuzick 2019-01-18T13:07:42Z single_species_phenotype obsolete deoxynivalenol absent from cell true PHIPO:0000504 A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-01-18T13:07:54Z single_species_phenotype obsolete deoxynivalenol present true PHIPO:0000505 Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment. alaynecuzick 2019-01-23T11:11:47Z FYPO:0000001 phipo Definition from FYPO. Unclear which namespace to enter under so currently 'floating' phenotype PHIPO:0000506 alaynecuzick 2019-01-23T11:16:14Z single_species_phenotype obsolete single species true PHIPO:0000507 alaynecuzick 2019-01-23T13:11:21Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate obsolete pathogen host interaction true PHIPO:0000509 A single species phenotype that is observed at the level of a population. alaynecuzick 2019-02-11T12:07:38Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Note: differentium is population level, and may reflect observation conditions. population phenotype PHIPO:0000510 A pathogen host interaction phenotype that is observed at the level of an individual cell. alaynecuzick 2019-02-11T12:19:47Z FYPO:0000002 pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen host interaction cell phenotype PHIPO:0000511 A pathogen host interaction phenotype that is observed at the level of a population of cells. alaynecuzick 2019-02-11T12:28:03Z FYPO:0000003 pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Note: differentium is population level, and may reflect observation conditions. no logical definition in FYPO obsolete pathogen host interaction cell population phenotype true PHIPO:0000512 A pathogen host interaction phenotype that is observed at the level of a host tissue (eg leaf, inflorescence, ear or kidney). alaynecuzick 2019-02-11T12:41:00Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete pathogen host interaction host tissue phenotype true PHIPO:0000513 An organism population phenotype in which no organisms in the population are viable. alaynecuzick 2019-02-11T13:01:17Z single_species_phenotype essential lethal inviable population PHIPO:0000514 A single organism cell population phenotype that reflects the proportion of the population that survive and develop normally. alaynecuzick 2019-02-11T13:07:36Z FYPO:0002057 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. population viability phenotype PHIPO:0000517 A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain more lipid droplets than normal. alaynecuzick 2019-03-19T13:18:56Z single_species_phenotype lipid droplets present in increased numbers PHIPO:0000518 A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain the same number of lipid droplets as normal (i.e. indistinguishable from wild type). alaynecuzick 2019-03-19T13:20:18Z FYPO:0006791 single_species_phenotype lipid droplets present in normal numbers PHIPO:0000519 A growth phenotype which describes the resistance of individuals or populations after exposure to piperacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to piperacillin PHIPO:0000520 A growth phenotype which describes the resistance of individuals or populations after exposure to florfenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to florfenicol PHIPO:0000521 A growth phenotype which describes the resistance of individuals or populations after exposure to boscalid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to boscalid PHIPO:0000523 A growth phenotype which describes the resistance of individuals or populations after exposure to sordarin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sordarin PHIPO:0000524 A growth phenotype which describes the resistance of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ketoconazole PHIPO:0000526 A growth phenotype which describes the resistance of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to carbenicillin PHIPO:0000527 A growth phenotype which describes the resistance of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to enrofloxacin PHIPO:0000528 A growth phenotype which describes the resistance of individuals or populations after exposure to prochloraz. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to prochloraz PHIPO:0000529 A growth phenotype which describes the resistance of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to virginiamycin PHIPO:0000530 A growth phenotype which describes the resistance of individuals or populations after exposure to triadimefon. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to triadimefon PHIPO:0000531 A growth phenotype which describes the resistance of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cercosporamide PHIPO:0000532 A growth phenotype which describes the resistance of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to oxytetracycline PHIPO:0000533 A growth phenotype which describes the resistance of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to gramicidin D PHIPO:0000534 A growth phenotype which describes the resistance of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to actinomycin D PHIPO:0000536 A growth phenotype which describes the resistance of individuals or populations after exposure to triclosan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to triclosan PHIPO:0000537 A growth phenotype which describes the resistance of individuals or populations after exposure to captan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to captan PHIPO:0000538 A growth phenotype which describes the resistance of individuals or populations after exposure to isoniazid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to isoniazid PHIPO:0000539 A growth phenotype which describes the resistance of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ciprofloxacin PHIPO:0000541 A growth phenotype which describes the resistance of individuals or populations after exposure to benznidazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to benznidazole PHIPO:0000542 A growth phenotype which describes the resistance of individuals or populations after exposure to ethambutol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ethambutol PHIPO:0000543 A growth phenotype which describes the resistance of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to teicoplanin PHIPO:0000544 A growth phenotype which describes the resistance of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cycloheximide PHIPO:0000545 A growth phenotype which describes the resistance of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to chlorothalonil PHIPO:0000546 A growth phenotype which describes the resistance of individuals or populations after exposure to cefotetan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefotetan PHIPO:0000548 A growth phenotype which describes the resistance of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to hygromycin B PHIPO:0000549 A growth phenotype which describes the resistance of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to triclabendazole PHIPO:0000550 A growth phenotype which describes the resistance of individuals or populations after exposure to ampicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ampicillin PHIPO:0000551 A growth phenotype which describes the resistance of individuals or populations after exposure to brassinin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to brassinin PHIPO:0000553 A growth phenotype which describes the resistance of individuals or populations after exposure to aztreonam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to aztreonam PHIPO:0000554 A growth phenotype which describes the resistance of individuals or populations after exposure to nisin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nisin PHIPO:0000555 A growth phenotype which describes the resistance of individuals or populations after exposure to tetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tetracycline PHIPO:0000556 A growth phenotype which describes the resistance of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to moxifloxacin PHIPO:0000557 A growth phenotype which describes the resistance of individuals or populations after exposure to myriocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to myriocin PHIPO:0000558 A growth phenotype which describes the resistance of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to benzylpenicillin PHIPO:0000559 A growth phenotype which describes the resistance of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to latrunculin A PHIPO:0000560 A growth phenotype which describes the resistance of individuals or populations after exposure to clindamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to clindamycin PHIPO:0000561 A growth phenotype which describes the resistance of individuals or populations after exposure to tylosin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tylosin PHIPO:0000562 A growth phenotype which describes the resistance of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to trovafloxacin PHIPO:0000563 A growth phenotype which describes the resistance of individuals or populations after exposure to furazolidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to furazolidone PHIPO:0000564 A growth phenotype which describes the resistance of individuals or populations after exposure to mecillinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to mecillinam PHIPO:0000565 A growth phenotype which describes the resistance of individuals or populations after exposure to cefixime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefixime PHIPO:0000566 A growth phenotype which describes the resistance of individuals or populations after exposure to tridemorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tridemorph PHIPO:0000567 A growth phenotype which describes the resistance of individuals or populations after exposure to mancozeb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to mancozeb PHIPO:0000569 A growth phenotype which describes the resistance of individuals or populations after exposure to netilmicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to netilmicin PHIPO:0000570 A growth phenotype which describes the resistance of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sulfanilamide PHIPO:0000571 A growth phenotype which describes the resistance of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to leptomycin B PHIPO:0000572 A growth phenotype which describes the resistance of individuals or populations after exposure to bleomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to bleomycin PHIPO:0000573 A growth phenotype which describes the resistance of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to gentamycin C1 PHIPO:0000574 A growth phenotype which describes the resistance of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to pyrazinecarboxamide PHIPO:0000575 A growth phenotype which describes the resistance of individuals or populations after exposure to micafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to micafungin PHIPO:0000576 A growth phenotype which describes the resistance of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to strobilurin A PHIPO:0000577 A growth phenotype which describes the resistance of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nikkomycin Z PHIPO:0000578 A growth phenotype which describes the resistance of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nifurtimox PHIPO:0000579 A growth phenotype which describes the resistance of individuals or populations after exposure to rotenone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to rotenone PHIPO:0000580 A growth phenotype which describes the resistance of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sulfadimethoxine PHIPO:0000581 A growth phenotype which describes the resistance of individuals or populations after exposure to flucytosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to flucytosine PHIPO:0000582 A growth phenotype which describes the resistance of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000552 single_species_phenotype resistance to cefuroxime PHIPO:0000583 A growth phenotype which describes the resistance of individuals or populations after exposure to antimycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to antimycin A PHIPO:0000584 A growth phenotype which describes the resistance of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to brefeldin A PHIPO:0000586 A growth phenotype which describes the resistance of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to anidulafungin PHIPO:0000587 A growth phenotype which describes the resistance of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to vinclozolin PHIPO:0000588 A growth phenotype which describes the resistance of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to trimethoprim PHIPO:0000589 A growth phenotype which describes the resistance of individuals or populations after exposure to mupirocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to mupirocin PHIPO:0000590 A growth phenotype which describes the resistance of individuals or populations after exposure to voriconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to voriconazole PHIPO:0000591 A growth phenotype which describes the resistance of individuals or populations after exposure to alexidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to alexidine PHIPO:0000592 A growth phenotype which describes the resistance of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fludioxonil PHIPO:0000593 A growth phenotype which describes the resistance of individuals or populations after exposure to oxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to oxacillin PHIPO:0000594 A growth phenotype which describes the resistance of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefpodoxime proxetil PHIPO:0000596 A growth phenotype which describes the resistance of individuals or populations after exposure to eflornithine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to eflornithine PHIPO:0000597 A growth phenotype which describes the resistance of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000540 single_species_phenotype resistance to polymyxin B resistance to polymyxin B1 PHIPO:0000598 A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to pyrimethanil PHIPO:0000599 A growth phenotype which describes the resistance of individuals or populations after exposure to telithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to telithromycin PHIPO:0000600 A growth phenotype which describes the resistance of individuals or populations after exposure to capreomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to capreomycin PHIPO:0000601 A growth phenotype which describes the resistance of individuals or populations after exposure to amikacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to amikacin PHIPO:0000602 A growth phenotype which describes the resistance of individuals or populations after exposure to ethionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ethionamide PHIPO:0000603 A growth phenotype which describes the resistance of individuals or populations after exposure to doxycycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to doxycycline PHIPO:0000604 A growth phenotype which describes the resistance of individuals or populations after exposure to meropenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to meropenem PHIPO:0000605 A growth phenotype which describes the resistance of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to 4-aminosalicylic acid PHIPO:0000606 A growth phenotype which describes the resistance of individuals or populations after exposure to rifampicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000535 single_species_phenotype resistance to rifampin resistance to rifampicin PHIPO:0000607 A growth phenotype which describes the resistance of individuals or populations after exposure to flutriafol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to flutriafol PHIPO:0000608 A growth phenotype which describes the resistance of individuals or populations after exposure to rifabutin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to rifabutin PHIPO:0000609 A growth phenotype which describes the resistance of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nalidixic acid PHIPO:0000610 A growth phenotype which describes the resistance of individuals or populations after exposure to linezolid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to linezolid PHIPO:0000611 A growth phenotype which describes the resistance of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fusidic acid PHIPO:0000612 A growth phenotype which describes the resistance of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tunicamycin PHIPO:0000613 A growth phenotype which describes the resistance of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to epoxyconazole PHIPO:0000615 A growth phenotype which describes the resistance of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to D-cycloserine PHIPO:0000616 A growth phenotype which describes the resistance of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to kanamycin A PHIPO:0000617 A growth phenotype which describes the resistance of individuals or populations after exposure to verapamil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to verapamil PHIPO:0000618 A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to streptomycin sulfate PHIPO:0000619 A growth phenotype which describes the resistance of individuals or populations after exposure to farnesol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to farnesol PHIPO:0000620 A growth phenotype which describes the resistance of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fenpropidin PHIPO:0000621 A growth phenotype which describes the resistance of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to gatifloxacin PHIPO:0000622 A growth phenotype which describes the resistance of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to erythromycin A PHIPO:0000623 A growth phenotype which describes the resistance of individuals or populations after exposure to bifonazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to bifonazole PHIPO:0000624 A growth phenotype which describes the resistance of individuals or populations after exposure to azithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to azithromycin PHIPO:0000625 A growth phenotype which describes the resistance of individuals or populations after exposure to posaconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to posaconazole PHIPO:0000626 A growth phenotype which describes the resistance of individuals or populations after exposure to prothionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to prothionamide PHIPO:0000627 A growth phenotype which describes the resistance of individuals or populations after exposure to copper. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to copper PHIPO:0000628 A growth phenotype which describes the resistance of individuals or populations after exposure to resveratrol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to resveratrol PHIPO:0000629 A growth phenotype which describes the resistance of individuals or populations after exposure to colistin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to colistin PHIPO:0000630 A growth phenotype which describes the resistance of individuals or populations after exposure to oligomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to oligomycin PHIPO:0000631 A growth phenotype which describes the resistance of individuals or populations after exposure to cefepime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefepime PHIPO:0000632 A growth phenotype which describes the resistance of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to hydrogen peroxide PHIPO:0000633 A growth phenotype which describes the resistance of individuals or populations after exposure to tigecycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tigecycline PHIPO:0000634 A growth phenotype which describes the resistance of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tricyclazole PHIPO:0000635 A growth phenotype which describes the resistance of individuals or populations after exposure to closantel. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to closantel PHIPO:0000636 A growth phenotype which describes the resistance of individuals or populations after exposure to diniconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to diniconazole PHIPO:0000639 A growth phenotype which describes the resistance of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to quinupristin-dalfopristin PHIPO:0000640 A growth phenotype which describes the resistance of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sparfloxacin PHIPO:0000641 A growth phenotype which describes the resistance of individuals or populations after exposure to cefaclor. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefaclor PHIPO:0000642 A growth phenotype which describes the resistance of individuals or populations after exposure to plumbagin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to plumbagin PHIPO:0000643 A growth phenotype which describes the resistance of individuals or populations after exposure to imipenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to imipenem PHIPO:0000644 A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to streptomycin PHIPO:0000645 A growth phenotype which describes the resistance of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ticarcillin PHIPO:0000646 A growth phenotype which describes the resistance of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fenhexamid PHIPO:0000647 A growth phenotype which describes the resistance of individuals or populations after exposure to abamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to abamectin PHIPO:0000648 A growth phenotype which describes the resistance of individuals or populations after exposure to miltefosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to miltefosine PHIPO:0000649 A growth phenotype which describes the resistance of individuals or populations after exposure to methicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to methicillin PHIPO:0000650 A growth phenotype which describes the resistance of individuals or populations after exposure to ertapenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ertapenem PHIPO:0000651 A growth phenotype which describes the resistance of individuals or populations after exposure to neomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to neomycin PHIPO:0000652 A growth phenotype which describes the resistance of individuals or populations after exposure to rapamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to rapamycin PHIPO:0000653 A growth phenotype which describes the resistance of individuals or populations after exposure to fluconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fluconazole PHIPO:0000654 A growth phenotype which describes the resistance of individuals or populations after exposure to valinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to valinomycin PHIPO:0000655 A growth phenotype which describes the resistance of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to salicylhydroxamic acid PHIPO:0000656 A growth phenotype which describes the resistance of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nicotinamide PHIPO:0000657 A growth phenotype which describes the resistance of individuals or populations after exposure to sulbactam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sulbactam PHIPO:0000658 A growth phenotype which describes the resistance of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to amoxicillin PHIPO:0000659 A growth phenotype which describes the resistance of individuals or populations after exposure to gentamicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to gentamicin PHIPO:0000660 A growth phenotype which describes the resistance of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ceftazidime PHIPO:0000661 A growth phenotype which describes the resistance of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to sulfisoxazole PHIPO:0000662 A growth phenotype which describes the resistance of individuals or populations after exposure to bacitracin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to bacitracin PHIPO:0000663 A growth phenotype which describes the resistance of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to difenoconazole PHIPO:0000664 A growth phenotype which describes the resistance of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to spiroxamine PHIPO:0000665 A growth phenotype which describes the resistance of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ofloxacin PHIPO:0000666 A growth phenotype which describes the resistance of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cyclosporine A PHIPO:0000667 A growth phenotype which describes the resistance of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefotaxime PHIPO:0000668 A growth phenotype which describes the resistance of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefoxitin PHIPO:0000669 A growth phenotype which describes the resistance of individuals or populations after exposure to fenarimol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to fenarimol PHIPO:0000670 A growth phenotype which describes the resistance of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to levofloxacin PHIPO:0000671 A growth phenotype which describes the resistance of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to spectinomycin PHIPO:0000672 A growth phenotype which describes the resistance of individuals or populations after exposure to pentamidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to pentamidine PHIPO:0000673 A growth phenotype which describes the resistance of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to thiabendazole PHIPO:0000674 A growth phenotype which describes the resistance of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to chlortetracycline PHIPO:0000675 A growth phenotype which describes the resistance of individuals or populations after exposure to itraconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to itraconazole PHIPO:0000676 A growth phenotype which describes the resistance of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nitrofurantoin PHIPO:0000677 A growth phenotype which describes the resistance of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to ceftriaxone PHIPO:0000678 A growth phenotype which describes the resistance of individuals or populations after exposure to paromomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to paromomycin PHIPO:0000679 A growth phenotype which describes the resistance of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tebuconazole PHIPO:0000681 A growth phenotype which describes the resistance of individuals or populations after exposure to nystatin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to nystatin PHIPO:0000682 A growth phenotype which describes the resistance of individuals or populations after exposure to propiconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to propiconazole PHIPO:0000684 A growth phenotype which describes the resistance of individuals or populations after exposure to minocycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to minocycline PHIPO:0000685 A growth phenotype which describes the resistance of individuals or populations after exposure to tobramycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tobramycin PHIPO:0000686 A growth phenotype which describes the resistance of individuals or populations after exposure to caspofungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to caspofungin PHIPO:0000688 A growth phenotype which describes the resistance of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to amphotericin B PHIPO:0000689 A growth phenotype which describes the resistance of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to chloramphenicol PHIPO:0000690 A growth phenotype which describes the resistance of individuals or populations after exposure to novobiocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to novobiocin PHIPO:0000691 A growth phenotype which describes the resistance of individuals or populations after exposure to emamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to emamectin PHIPO:0000692 A growth phenotype which describes the resistance of individuals or populations after exposure to penicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to penicillin PHIPO:0000693 A growth phenotype which describes the resistance of individuals or populations after exposure to carbapenems. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to carbapenems PHIPO:0000694 A growth phenotype which describes the resistance of individuals or populations after exposure to daptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to daptomycin PHIPO:0000695 A growth phenotype which describes the resistance of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to clarithromycin PHIPO:0000696 A growth phenotype which describes the resistance of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to copper sulphate PHIPO:0000697 A growth phenotype which describes the resistance of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000702 single_species_phenotype resistance to phosphomycin resistance to fosfomycin PHIPO:0000698 A growth phenotype which describes the resistance of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to trichostatin A PHIPO:0000699 A growth phenotype which describes the resistance of individuals or populations after exposure to doripenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to doripenem PHIPO:0000700 A growth phenotype which describes the resistance of individuals or populations after exposure to miconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to miconazole PHIPO:0000701 A growth phenotype which describes the resistance of individuals or populations after exposure to vancomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to vancomycin PHIPO:0000703 A growth phenotype which describes the resistance of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to aureobasidin A PHIPO:0000704 A growth phenotype which describes the resistance of individuals or populations after exposure to lincomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to lincomycin PHIPO:0000705 A growth phenotype which describes the resistance of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to norfloxacin PHIPO:0000706 A growth phenotype which describes the resistance of individuals or populations after exposure to tiamulin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to tiamulin PHIPO:0000707 A growth phenotype which describes the resistance of individuals or populations after exposure to hymexazol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to hymexazol PHIPO:0000708 A growth phenotype which describes the resistance of individuals or populations after exposure to cephalexin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cephalexin PHIPO:0000709 A growth phenotype which describes the resistance of individuals or populations after exposure to clofazimine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to clofazimine PHIPO:0000710 A growth phenotype which describes the resistance of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to dicloxacillin PHIPO:0000711 A growth phenotype which describes the resistance of individuals or populations after exposure to camptothecin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to camptothecin PHIPO:0000712 A growth phenotype which describes the resistance of individuals or populations after exposure to cefazolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype resistance to cefazolin PHIPO:0000713 A growth phenotype which describes the sensitivity of individuals or populations after exposure to mupirocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to mupirocin PHIPO:0000716 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefixime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefixime PHIPO:0000717 A growth phenotype which describes the sensitivity of individuals or populations after exposure to minocycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to minocycline PHIPO:0000718 A growth phenotype which describes the sensitivity of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000857 single_species_phenotype sensitive to polymyxin B sensitive to polymyxin B1 PHIPO:0000719 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fusidic acid PHIPO:0000720 A growth phenotype which describes the sensitivity of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to brefeldin A PHIPO:0000721 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ethionamide PHIPO:0000722 A growth phenotype which describes the sensitivity of individuals or populations after exposure to rotenone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to rotenone PHIPO:0000723 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to pyrazinecarboxamide PHIPO:0000724 A growth phenotype which describes the sensitivity of individuals or populations after exposure to alexidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to alexidine PHIPO:0000726 A growth phenotype which describes the sensitivity of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to chloramphenicol PHIPO:0000727 A growth phenotype which describes the sensitivity of individuals or populations after exposure to clofazimine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to clofazimine PHIPO:0000728 A growth phenotype which describes the sensitivity of individuals or populations after exposure to emamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to emamectin PHIPO:0000729 A growth phenotype which describes the sensitivity of individuals or populations after exposure to miltefosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to miltefosine PHIPO:0000730 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sulfadimethoxine PHIPO:0000732 A growth phenotype which describes the sensitivity of individuals or populations after exposure to doripenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to doripenem PHIPO:0000733 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefaclor. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefaclor PHIPO:0000734 A growth phenotype which describes the sensitivity of individuals or populations after exposure to plumbagin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to plumbagin PHIPO:0000735 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefotaxime PHIPO:0000736 A growth phenotype which describes the sensitivity of individuals or populations after exposure to benznidazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to benznidazole PHIPO:0000737 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cyclosporine A PHIPO:0000738 A growth phenotype which describes the sensitivity of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to spectinomycin PHIPO:0000739 A growth phenotype which describes the sensitivity of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to latrunculin A PHIPO:0000740 A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to oxacillin PHIPO:0000741 A growth phenotype which describes the sensitivity of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to difenoconazole PHIPO:0000742 A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclosan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to triclosan PHIPO:0000743 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tridemorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tridemorph PHIPO:0000744 A growth phenotype which describes the sensitivity of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to virginiamycin PHIPO:0000745 A growth phenotype which describes the sensitivity of individuals or populations after exposure to neomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to neomycin PHIPO:0000746 A growth phenotype which describes the sensitivity of individuals or populations after exposure to voriconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to voriconazole PHIPO:0000747 A growth phenotype which describes the sensitivity of individuals or populations after exposure to brassinin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to brassinin PHIPO:0000748 A growth phenotype which describes the sensitivity of individuals or populations after exposure to daptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to daptomycin PHIPO:0000749 A growth phenotype which describes the sensitivity of individuals or populations after exposure to bleomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to bleomycin PHIPO:0000750 A growth phenotype which describes the sensitivity of individuals or populations after exposure to aztreonam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to aztreonam PHIPO:0000751 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fludioxonil PHIPO:0000753 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ceftriaxone PHIPO:0000754 A growth phenotype which describes the sensitivity of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to leptomycin B PHIPO:0000755 A growth phenotype which describes the sensitivity of individuals or populations after exposure to amikacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to amikacin PHIPO:0000756 A growth phenotype which describes the sensitivity of individuals or populations after exposure to resveratrol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to resveratrol PHIPO:0000757 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fenhexamid PHIPO:0000758 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefpodoxime proxetil PHIPO:0000759 A growth phenotype which describes the sensitivity of individuals or populations after exposure to myriocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to myriocin PHIPO:0000760 A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to gentamicin PHIPO:0000761 A growth phenotype which describes the sensitivity of individuals or populations after exposure to valinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to valinomycin PHIPO:0000762 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tigecycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tigecycline PHIPO:0000763 A growth phenotype which describes the sensitivity of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to moxifloxacin PHIPO:0000764 A growth phenotype which describes the sensitivity of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to kanamycin A PHIPO:0000765 A growth phenotype which describes the sensitivity of individuals or populations after exposure to methicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to methicillin PHIPO:0000766 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pentamidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to pentamidine PHIPO:0000767 A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to gentamycin C1 PHIPO:0000768 A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to thiabendazole PHIPO:0000769 A growth phenotype which describes the sensitivity of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to gatifloxacin PHIPO:0000770 A growth phenotype which describes the sensitivity of individuals or populations after exposure to mecillinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to mecillinam PHIPO:0000771 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ampicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ampicillin PHIPO:0000772 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotetan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefotetan PHIPO:0000773 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nystatin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nystatin PHIPO:0000774 A growth phenotype which describes the sensitivity of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to vinclozolin PHIPO:0000775 A growth phenotype which describes the sensitivity of individuals or populations after exposure to flucytosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to flucytosine PHIPO:0000776 A growth phenotype which describes the sensitivity of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to trichostatin A PHIPO:0000777 A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to oxytetracycline PHIPO:0000778 A growth phenotype which describes the sensitivity of individuals or populations after exposure to eflornithine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to eflornithine PHIPO:0000779 A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to streptomycin PHIPO:0000780 A growth phenotype which describes the sensitivity of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to epoxyconazole PHIPO:0000781 A growth phenotype which describes the sensitivity of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to trimethoprim PHIPO:0000782 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nifurtimox PHIPO:0000783 A growth phenotype which describes the sensitivity of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to clarithromycin PHIPO:0000784 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nisin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nisin PHIPO:0000785 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sulfanilamide PHIPO:0000786 A growth phenotype which describes the sensitivity of individuals or populations after exposure to oligomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to oligomycin PHIPO:0000788 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000787 single_species_phenotype sensitive to phosphomycin sensitive to fosfomycin PHIPO:0000789 A growth phenotype which describes the sensitivity of individuals or populations after exposure to telithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to telithromycin PHIPO:0000791 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nitrofurantoin PHIPO:0000792 A growth phenotype which describes the sensitivity of individuals or populations after exposure to linezolid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to linezolid PHIPO:0000793 A growth phenotype which describes the sensitivity of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to anidulafungin PHIPO:0000795 A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to carbenicillin PHIPO:0000796 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tunicamycin PHIPO:0000797 A growth phenotype which describes the sensitivity of individuals or populations after exposure to caspofungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to caspofungin PHIPO:0000798 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenarimol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fenarimol PHIPO:0000799 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ciprofloxacin PHIPO:0000800 A growth phenotype which describes the sensitivity of individuals or populations after exposure to farnesol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to farnesol PHIPO:0000801 A growth phenotype which describes the sensitivity of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to amphotericin B PHIPO:0000802 A growth phenotype which describes the sensitivity of individuals or populations after exposure to vancomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to vancomycin PHIPO:0000803 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ketoconazole PHIPO:0000804 A growth phenotype which describes the sensitivity of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to strobilurin A PHIPO:0000805 A growth phenotype which describes the sensitivity of individuals or populations after exposure to colistin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to colistin PHIPO:0000806 A growth phenotype which describes the sensitivity of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to trovafloxacin PHIPO:0000807 A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to triclabendazole PHIPO:0000808 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to pyrimethanil PHIPO:0000809 A growth phenotype which describes the sensitivity of individuals or populations after exposure to florfenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to florfenicol PHIPO:0000810 A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutriafol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to flutriafol PHIPO:0000811 A growth phenotype which describes the sensitivity of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to teicoplanin PHIPO:0000812 A growth phenotype which describes the sensitivity of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to norfloxacin PHIPO:0000814 A growth phenotype which describes the sensitivity of individuals or populations after exposure to closantel. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to closantel PHIPO:0000815 A growth phenotype which describes the sensitivity of individuals or populations after exposure to penicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to penicillin PHIPO:0000816 A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to prothionamide PHIPO:0000817 A growth phenotype which describes the sensitivity of individuals or populations after exposure to isoniazid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to isoniazid PHIPO:0000818 A growth phenotype which describes the sensitivity of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to salicylhydroxamic acid PHIPO:0000819 A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbapenems. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to carbapenems PHIPO:0000820 A growth phenotype which describes the sensitivity of individuals or populations after exposure to abamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to abamectin PHIPO:0000822 A growth phenotype which describes the sensitivity of individuals or populations after exposure to antimycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to antimycin A PHIPO:0000823 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cercosporamide PHIPO:0000824 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tiamulin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tiamulin PHIPO:0000825 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tebuconazole PHIPO:0000826 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ticarcillin PHIPO:0000827 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nicotinamide PHIPO:0000828 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tricyclazole PHIPO:0000829 A growth phenotype which describes the sensitivity of individuals or populations after exposure to paromomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to paromomycin PHIPO:0000830 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ofloxacin PHIPO:0000831 A growth phenotype which describes the sensitivity of individuals or populations after exposure to triadimefon. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to triadimefon PHIPO:0000832 A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to copper sulphate PHIPO:0000833 A growth phenotype which describes the sensitivity of individuals or populations after exposure to imipenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to imipenem PHIPO:0000834 A growth phenotype which describes the sensitivity of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to quinupristin-dalfopristin PHIPO:0000835 A growth phenotype which describes the sensitivity of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to aureobasidin A PHIPO:0000836 A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifampicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000856 single_species_phenotype sensitive to rifampin sensitive to rifampicin PHIPO:0000837 A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifabutin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to rifabutin PHIPO:0000838 A growth phenotype which describes the sensitivity of individuals or populations after exposure to diniconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to diniconazole PHIPO:0000839 A growth phenotype which describes the sensitivity of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to actinomycin D PHIPO:0000840 A growth phenotype which describes the sensitivity of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to dicloxacillin PHIPO:0000841 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z PHIPO:0000821 single_species_phenotype sensitive to cefuroxime PHIPO:0000842 A growth phenotype which describes the sensitivity of individuals or populations after exposure to piperacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to piperacillin PHIPO:0000843 A growth phenotype which describes the sensitivity of individuals or populations after exposure to bacitracin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to bacitracin PHIPO:0000844 A growth phenotype which describes the sensitivity of individuals or populations after exposure to propiconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to propiconazole PHIPO:0000845 A growth phenotype which describes the sensitivity of individuals or populations after exposure to meropenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to meropenem PHIPO:0000846 A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to chlorothalonil PHIPO:0000847 A growth phenotype which describes the sensitivity of individuals or populations after exposure to posaconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to posaconazole PHIPO:0000848 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cephalexin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cephalexin PHIPO:0000850 A growth phenotype which describes the sensitivity of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to 4-aminosalicylic acid PHIPO:0000851 A growth phenotype which describes the sensitivity of individuals or populations after exposure to captan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to captan PHIPO:0000853 A growth phenotype which describes the sensitivity of individuals or populations after exposure to capreomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to capreomycin PHIPO:0000854 A growth phenotype which describes the sensitivity of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to gramicidin D PHIPO:0000855 A growth phenotype which describes the sensitivity of individuals or populations after exposure to doxycycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to doxycycline PHIPO:0000858 A growth phenotype which describes the sensitivity of individuals or populations after exposure to bifonazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to bifonazole PHIPO:0000859 A growth phenotype which describes the sensitivity of individuals or populations after exposure to micafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to micafungin PHIPO:0000860 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ertapenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ertapenem PHIPO:0000861 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cycloheximide PHIPO:0000862 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ceftazidime PHIPO:0000863 A growth phenotype which describes the sensitivity of individuals or populations after exposure to camptothecin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to camptothecin PHIPO:0000864 A growth phenotype which describes the sensitivity of individuals or populations after exposure to netilmicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to netilmicin PHIPO:0000865 A growth phenotype which describes the sensitivity of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to benzylpenicillin PHIPO:0000866 A growth phenotype which describes the sensitivity of individuals or populations after exposure to hymexazol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to hymexazol PHIPO:0000867 A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to streptomycin sulfate PHIPO:0000868 A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to chlortetracycline PHIPO:0000869 A growth phenotype which describes the sensitivity of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to D-cycloserine PHIPO:0000870 A growth phenotype which describes the sensitivity of individuals or populations after exposure to miconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to miconazole PHIPO:0000871 A growth phenotype which describes the sensitivity of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to erythromycin A PHIPO:0000872 A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to copper PHIPO:0000873 A growth phenotype which describes the sensitivity of individuals or populations after exposure to rapamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to rapamycin PHIPO:0000874 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tobramycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tobramycin PHIPO:0000875 A growth phenotype which describes the sensitivity of individuals or populations after exposure to verapamil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to verapamil PHIPO:0000876 A growth phenotype which describes the sensitivity of individuals or populations after exposure to furazolidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to furazolidone PHIPO:0000877 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefoxitin PHIPO:0000878 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fenpropidin PHIPO:0000879 A growth phenotype which describes the sensitivity of individuals or populations after exposure to itraconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to itraconazole PHIPO:0000880 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sulfisoxazole PHIPO:0000881 A growth phenotype which describes the sensitivity of individuals or populations after exposure to lincomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to lincomycin PHIPO:0000882 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tetracycline PHIPO:0000883 A growth phenotype which describes the sensitivity of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to levofloxacin PHIPO:0000884 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefazolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefazolin PHIPO:0000885 A growth phenotype which describes the sensitivity of individuals or populations after exposure to novobiocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to novobiocin PHIPO:0000886 A growth phenotype which describes the sensitivity of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to amoxicillin PHIPO:0000887 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethambutol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to ethambutol PHIPO:0000888 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tylosin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to tylosin PHIPO:0000889 A growth phenotype which describes the sensitivity of individuals or populations after exposure to clindamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to clindamycin PHIPO:0000890 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to fluconazole PHIPO:0000891 A growth phenotype which describes the sensitivity of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to hygromycin B PHIPO:0000892 A growth phenotype which describes the sensitivity of individuals or populations after exposure to boscalid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to boscalid PHIPO:0000893 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefepime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to cefepime PHIPO:0000894 A growth phenotype which describes the sensitivity of individuals or populations after exposure to prochloraz. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to prochloraz PHIPO:0000895 A growth phenotype which describes the sensitivity of individuals or populations after exposure to mancozeb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to mancozeb PHIPO:0000896 A growth phenotype which describes the sensitivity of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to spiroxamine PHIPO:0000897 A growth phenotype which describes the sensitivity of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to enrofloxacin PHIPO:0000898 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nalidixic acid PHIPO:0000899 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sordarin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sordarin PHIPO:0000901 A growth phenotype which describes the sensitivity of individuals or populations after exposure to azithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to azithromycin PHIPO:0000902 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sparfloxacin PHIPO:0000903 A growth phenotype which describes the sensitivity of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to nikkomycin Z PHIPO:0000904 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulbactam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2018-03-20T14:29:00Z single_species_phenotype sensitive to sulbactam PHIPO:0000924 A pathogen host interaction phenotype, which affects a pathogen induced host oxidative burst level (GO:0002679). alaynecuzick 2019-05-01T09:18:19Z GO:0002679 pathogen host interaction respiratory burst phenotype pathogen induced host oxidative burst level phenotype pathogen-induced host oxidative burst level phenotype pathogen_host_interaction_phenotype Definition adapted from GO:0002679 respiratory burst involved in defense response. host defense-induced oxidative burst level phenotype PHIPO:0000925 A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is abnormal. alaynecuzick 2019-05-01T10:52:19Z abnormal cell wall integrity single_species_phenotype abnormal cell wall organization or biogenesis PHIPO:0000927 A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is present. alaynecuzick 2019-05-01T10:52:28Z PHIPO:0000926 host H202 production resulting from oxidative burst increased host H202 production resulting from oxidative burst pathogen induced host ROS present pathogen induced host oxidative burst present pathogen induced host reactive oxygen species present pathogen induced host respiratory burst present pathogen-induced host ROS present pathogen-induced host reactive oxygen species present presence of pathogen induced host ROS pathogen_host_interaction_phenotype presence of pathogen induced host reactive oxygen species host defense-induced reactive oxygen species present PHIPO:0000928 A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is absent or at a level too low to detect. alaynecuzick 2019-05-01T10:53:36Z absence of pathogen induced host ROS pathogen induced host ROS absent pathogen induced host oxidative burst absent pathogen induced host reactive oxygen species absent pathogen induced host respiratory burst absent pathogen-induced host ROS absent pathogen-induced host reactive oxygen species absent pathogen_host_interaction_phenotype absence of pathogen induced host reactive oxygen species host defense-induced reactive oxygen species absent PHIPO:0000929 A phenotype in which a specific cellular process is abnormal. alaynecuzick 2019-05-01T10:58:54Z FYPO:0000628 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. abnormal cellular process PHIPO:0000930 A phenotype that affects a cellular process. alaynecuzick 2019-05-01T10:59:15Z FYPO:0000114 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. cellular process phenotype PHIPO:0000931 A phenotype that affects cell wall organization or biogenesis. alaynecuzick 2019-05-01T10:59:55Z cell wall integrity phenotype single_species_phenotype cell wall organization or biogenesis phenotype PHIPO:0000932 A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-05-01T11:00:10Z FYPO:0000627 single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. normal cellular process PHIPO:0000934 A single organism phenotype in which the amount, distribution, or morphology of all or part of the nucleus is abnormal. alaynecuzick 2019-05-08T13:37:01Z FYPO:0002403 single_species_phenotype abnormal nucleus PHIPO:0000935 A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is decreased. alaynecuzick 2019-05-17T10:49:13Z decreased cell wall organization or biogenesis single_species_phenotype decreased cell wall integrity PHIPO:0000936 An single species phenotype in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. alaynecuzick 2019-05-21T10:29:14Z FYPO:0002488 single_species_phenotype cell lysis PHIPO:0000937 An single species phenotype in which an asexual spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. alaynecuzick 2019-05-21T10:29:30Z FYPO:0002489 asexual spore cytolysis present conidia lysis present single_species_phenotype asexual spore lysis present PHIPO:0000938 An single species phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. alaynecuzick 2019-05-21T10:30:07Z FYPO:0000647 single_species_phenotype vegetative cell lysis PHIPO:0000939 An single species phenotype in which an asexual spore does not lyse, i.e. the plasma membrane ruptures and cytoplasm is lost. alaynecuzick 2019-05-21T11:22:31Z FYPO:0002489 asexual spore cytolysis absent conidia lysis absent single_species_phenotype asexual spore lysis absent PHIPO:0000940 A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is abnormal. (GO:0032179) alaynecuzick 2019-05-21T11:34:47Z single_species_phenotype abnormal germ tube PHIPO:0000941 A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is shorter than normal. (GO:0032179) alaynecuzick 2019-05-21T11:35:21Z single_species_phenotype short germ tube PHIPO:0000943 A growth phenotype which describes the sensitivity of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2019-05-21T11:55:15Z PHIPO:0000849 single_species_phenotype sensitive to hydrogen peroxide PHIPO:0000944 A single species cell phenotype in which the amount of a specific substance measured in a cell differs from normal. alaynecuzick 2019-05-21T11:59:04Z FYPO:0000989 abnormal level of substance in cell single_species_phenotype altered level of substance in cell PHIPO:0000945 A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell differs from normal. alaynecuzick 2019-05-21T12:00:07Z FYPO:0002142 abnormal cellular ROS level abnormal cellular reactive oxygen species level altered cellular ROS level single_species_phenotype abnormal cellular ROS accumulation altered cellular reactive oxygen species level PHIPO:0000946 A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal. alaynecuzick 2019-05-21T12:01:32Z decreased cellular ROS level reduced cellular ROS level single_species_phenotype decreased cellular reactive oxygen species level PHIPO:0000947 A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal. alaynecuzick 2019-05-21T12:01:41Z increased cellular ROS level single_species_phenotype increased cellular reactive oxygen species level PHIPO:0000948 A pathogen host interaction where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction does not exhibit mutualism. alaynecuzick 2019-05-24T11:02:11Z pathogen_host_interaction_phenotype qc_do_not_annotate mutualism absent PHIPO:0000949 A pathogen colonization of host phenotype which affects the penetration of the pathogen into the body, tissues, or cells of the host organism (GO:0044409). alaynecuzick 2019-05-24T11:54:37Z pathogen_host_interaction_phenotype This covers formation of any penetration structure, the process of penetration, and phenotypes which affect number of penetration structures, or the timing. pathogen entry into host phenotype PHIPO:0000950 alaynecuzick 2019-05-24T12:00:40Z pathogen_host_interaction_phenotype Note: to add asexual/sexual etc obsolete pathogen spore germination on host phenotype true PHIPO:0000951 A pathogen host phenotype which affects the vegetative growth or proliferation of the pathogen inside the host (e.g. after entry by penetration or infiltration). alaynecuzick 2019-05-24T12:07:04Z PHIPO:0000471 pathogen_host_interaction_phenotype pathogen biomass within host phenotype pathogen growth within host phenotype PHIPO:0000952 A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abolished (it was present as is now absent). alaynecuzick 2019-05-24T12:21:58Z pathogen_host_interaction_phenotype abolished pathogen growth within host PHIPO:0000953 A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is present. alaynecuzick 2019-05-24T12:23:57Z pathogen infection structure present when near host pathogen_host_interaction_phenotype pathogen penetration structure present when near host PHIPO:0000954 A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is present. alaynecuzick 2019-05-24T12:25:01Z PHIPO:0000354 normal post penetration of host by pathogen pathogen growth present within host pathogen_host_interaction_phenotype normal pathogen growth within host presence of pathogen growth within host PHIPO:0000955 A pathogen growth with host phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished. alaynecuzick 2019-05-24T13:17:03Z abolished formation of pathogen infection structure when near host pathogen_host_interaction_phenotype abolished formation of pathogen penetration structure when near host PHIPO:0000956 A population phenotype in which the frequency of occurrence of asexual spore germination is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-06-10T09:09:38Z normal conidia germination frequency single_species_phenotype normal asexual spore germination frequency PHIPO:0000959 A single species individual organism phenotype where the accumulation of melanin in a cell is normal. alaynecuzick 2019-06-11T09:24:45Z melanization single_species_phenotype normal cellular melanin accumulation PHIPO:0000961 A single species phenotype that affects the morphology of a cell. alaynecuzick 2019-06-11T10:58:14Z single_species_phenotype obsolete cell morphology phenotype true PHIPO:0000962 A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is decreased. alaynecuzick 2019-06-12T10:48:26Z pathogen_host_interaction_phenotype decreased filamentous growth on host surface PHIPO:0000964 A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished on a specific host genotype. alaynecuzick 2019-06-26T11:54:44Z abolished virulence pathogen_host_interaction_phenotype avirulence qc_do_not_annotate For use in the annotation extension infective ability. Note this pathogen may still be pathogenic on an alternate host genotype. Note that avirulence means loss of pathogenicity in medical terminology. loss of virulence PHIPO:0000965 A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished when observed in an interaction with a pathogen mutant which was previously engineered to gain pathogenicity. alaynecuzick 2019-06-26T12:27:44Z pathogen_host_interaction_phenotype qc_extension_only For use in the annotation extension infective ability. Note this pathogen may still be pathogenic on an alternate host genotype. obsolete loss of virulence of gain of pathogenicity mutant true PHIPO:0000966 A single species pathogen growth phenotype in which the pathogen specialized host penetration structure is present when assessed for penetration ability on a given experimental substance/membrane. alaynecuzick 2019-07-05T09:48:18Z pathogen infection structure present single_species_phenotype pathogen_phenotype pathogen penetration structure present PHIPO:0000967 A single species pathogen penetration phenotype in in which the ability of the pathogen to penetrate a given experimental substance/membrane is abolished. alaynecuzick 2019-07-05T10:18:20Z single_species_phenotype pathogen_phenotype abolished pathogen penetration across the barrier PHIPO:0000968 A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is absent. alaynecuzick 2019-07-05T11:08:06Z single_species_phenotype pathogen_phenotype absent pathogen growth after penetration of the barrier PHIPO:0000969 A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is present. alaynecuzick 2019-07-05T11:08:42Z single_species_phenotype pathogen_phenotype present pathogen growth after penetration of the barrier PHIPO:0000970 A single organism phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer autophagosomes than normal (GO:0005776). alaynecuzick 2019-07-16T11:41:18Z single_species_phenotype autophagosomes present in decreased numbers PHIPO:0000971 A single organism phenotype observed in the vegetative growth phase of the life cycle in which the ability of the organism to form autophagosomes is abolished (they were present and are now absent) (GO:0005776). alaynecuzick 2019-07-16T12:03:12Z single_species_phenotype abolished formation of autophagosomes PHIPO:0000972 A single organism phenotype in which a protein does not localize to, and is therefore absent from the autophagosome (GO:0005776). alaynecuzick 2019-07-16T13:07:53Z single_species_phenotype We recommend noting which protein(s) were used in the assay when annotating to this term. abolished protein localization to autophagosome PHIPO:0000973 A single organism phenotype that affects a double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy (GO:0005776). alaynecuzick 2019-07-16T13:22:46Z single_species_phenotype autophagosome phenotype PHIPO:0000974 A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser than normal. alaynecuzick 2019-07-27T10:55:41Z FYPO:0000046 single_species_phenotype slower growth decreased unicellular population growth PHIPO:0000975 A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is greater than normal. alaynecuzick 2019-07-27T10:58:04Z FYPO:0003937 single_species_phenotype faster growth increased unicellular population growth PHIPO:0000976 A single organism metabolic process phenotype in which the occurrence of lipid droplet degradation (lipolysis) is decreased (GO:0016042 and GO:0005811). alaynecuzick 2019-07-27T11:17:17Z decreased lipolysis single_species_phenotype decreased lipid droplet degradation PHIPO:0000977 A phenotype in which a population of a single-species shows increased sensitivity to sodium dodecyl sulfate (SDS), manifested as an affect on the extent of population growth. (CHEBI:8984). alaynecuzick 2019-07-27T11:30:10Z single_species_phenotype sensitive to sodium dodecyl sulfate PHIPO:0000978 A phenotype in which a population of a single-species shows increased sensitivity to sodium chloride, manifested as an affect on the extent of population growth. (CHEBI:26710). alaynecuzick 2019-07-27T11:32:29Z single_species_phenotype sensitive to sodium chloride PHIPO:0000979 A phenotype in which a population of a single-species shows increased sensitivity to 1,4-dithiothreitol (DTT), manifested as an affect on the extent of population growth. (CHEBI:18320). alaynecuzick 2019-07-27T11:32:42Z single_species_phenotype sensitive to dithiothreitol PHIPO:0000980 A reproductive phenotype where the morphology of the sexual spore is normal (FAO:0000017). The product of meiosis. alaynecuzick 2019-07-27T12:17:27Z single_species_phenotype normal sexual spore morphology PHIPO:0000981 A reproductive process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phases of a meiotic cell cycle. (GO:0140013). alaynecuzick 2019-07-27T13:29:17Z FYPO:0000051 abnormal meiotic nuclear division single_species_phenotype abnormal meiosis PHIPO:0000982 A reproductive process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type). (GO:0140013). alaynecuzick 2019-07-27T13:33:11Z FYPO:0000478 normal meiotic nuclear division single_species_phenotype normal meiosis PHIPO:0000983 A reproductive process phenotype in which a cell does not proceed normally through a meiotic cell cycle (GO:0051321). alaynecuzick 2019-07-27T13:48:15Z FYPO:0000052 single_species_phenotype abnormal meiotic cell cycle PHIPO:0000984 A reproductive process phenotype in which a cell proceeds normally through a meiotic cell cycle (GO:0051321). alaynecuzick 2019-07-27T13:52:11Z single_species_phenotype normal meiotic cell cycle PHIPO:0000985 A phenotype where the process of host tissue cell death causing a host lesion occurs to a lesser extent than normal. alaynecuzick 2018-10-02T08:58:26Z PHIPO:0000223 PHIPO:0000225 pathogen_host_interaction_phenotype decreased number of pathogen-associated host lesions decreased size of pathogen-associated host lesion The lesion can be induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. decreased extent of pathogen-associated host lesions PHIPO:0000986 A phenotype where the process of host tissue cell death causing a host lesion occurs to a greater extent than normal. alaynecuzick 2018-10-02T08:56:00Z PHIPO:0000221 PHIPO:0000222 pathogen_host_interaction_phenotype increased number of pathogen-associated host lesions increased size of pathogen-associated host lesion The lesion can be induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. increased extent of pathogen-associated host lesions PHIPO:0000987 A cell phenotype in which the amount of a specific substance measured in a cell within a pathogen host interaction differs from normal. alaynecuzick 2019-08-10T12:17:39Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete altered level of substance phenotype in a pathogen host interaction true PHIPO:0000988 A cell phenotype in which the amount of protein measured in a pathogen or host cell differs from normal. Total protein or a specific protein may be affected. alaynecuzick 2019-08-10T12:19:50Z pathogen_host_interaction_phenotype obsolete altered protein level in a pathogen host interaction true PHIPO:0000989 A pathogen host interaction phenotype, in which the level of pathogen protein usually present during infection is lower than normal. alaynecuzick 2019-08-10T12:20:29Z pathogen_host_interaction_phenotype decreased level of pathogen protein within host PHIPO:0000990 A pathogen host interaction phenotype, in which the pathogen produced protein usually present during infection is absent. alaynecuzick 2019-08-10T12:20:59Z pathogen_host_interaction_phenotype obsolete absence of pathogen protein with host true PHIPO:0000991 A pathogen host interaction phenotype, in which the level of host protein usually present during infection is higher than normal. alaynecuzick 2019-08-10T12:22:12Z increased level of host protein involved in a pathogen host interaction pathogen_host_interaction_phenotype increased level of host defense-induced protein PHIPO:0000992 A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is higher than normal. alaynecuzick 2019-08-10T12:23:36Z increased expression of a host defense related protein involved in a pathogen interaction pathogen_host_interaction_phenotype increased expression of a host defense-related protein involved in a pathogen interaction PHIPO:0000993 A cell phenotype in which the amount of RNA measured in a pathogen or host cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-08-10T12:30:53Z pathogen_host_interaction_phenotype obsolete altered RNA level in a pathogen host interaction true PHIPO:0000994 A cell phenotype in which the amount of RNA measured in a pathogen or host cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-08-10T12:31:25Z pathogen_host_interaction_phenotype obsolete decreased RNA level in a pathogen host interaction true PHIPO:0000995 A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is lower than normal. alaynecuzick 2019-08-10T12:32:05Z pathogen_host_interaction_phenotype decreased level of pathogen RNA within host PHIPO:0000998 A pathogen host interaction phenotype which affects the pathogen morphology during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:48:27Z pathogen_host_interaction_phenotype pathogen morphology phenotype during colonization of host PHIPO:0000999 A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:49:02Z pathogen_host_interaction_phenotype abnormal pathogen morphology during colonization of host PHIPO:0001000 A pathogen host interaction phenotype where the morphology of the pathogen terminal hyphae during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:49:58Z abnormal pathogen swollen terminal hyphae during colonization of host pathogen_host_interaction_phenotype abnormal pathogen swollen terminal hyphae during cell to cell migration PHIPO:0001001 A pathogen host interaction phenotype where the morphology of the pathogen septin collar (GO:0032173) during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:51:23Z pathogen_host_interaction_phenotype abnormal organization of pathogen septin collar during colonization of host update Go term when available to 'septin collar of invasive fungi' abnormal organization of pathogen septin collar during cell to cell migration PHIPO:0001002 A pathogen host interaction phenotype which affects the host morphology during pathogen invasion. This relates to the pathogen colonization of the body, tissues, or cells of the host organism alaynecuzick 2019-08-10T13:51:57Z pathogen_host_interaction_phenotype host morphology phenotype during pathogen invasion PHIPO:0001003 A pathogen host interaction phenotype where the morphology of the host extra-invasive hyphal membrane (GO:0085039) during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:52:53Z normal formation of BIC (biotrophic interfacial complex) pathogen_host_interaction_phenotype normal formation of extra-invasive hyphal membrane PHIPO:0001004 A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:56:49Z pathogen_host_interaction_phenotype normal pathogen morphology during colonization of host PHIPO:0001005 A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:58:16Z pathogen_host_interaction_phenotype normal host morphology during pathogen invasion PHIPO:0001006 A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T13:58:30Z pathogen_host_interaction_phenotype abnormal host morphology during pathogen invasion PHIPO:0001007 A pathogen host interaction phenotype which affects the morphology of the pathogen or the host during pathogen colonization of the host. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-08-10T14:19:52Z pathogen_host_interaction_phenotype obsolete pathogen colonization of host morphology phenotype true PHIPO:0001008 A phenotype in which a specific transport process is abnormal in the vegetative growth phase of the life cycle. alaynecuzick 2019-08-10T15:03:45Z FYPO:0005973 single_species_phenotype abnormal transport during vegetative growth PHIPO:0001009 A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal. alaynecuzick 2019-08-10T15:06:50Z FYPO:0000213 single_species_phenotype abnormal vesicle-mediated transport during vegetative growth PHIPO:0001010 A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-08-10T15:06:57Z FYPO:0006432 single_species_phenotype normal vesicle-mediated transport during vegetative growth PHIPO:0001011 A single organism cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-08-10T15:11:18Z FYPO:0001071 single_species_phenotype normal transport PHIPO:0001012 A pathogen host interaction phenotype which affects the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037). alaynecuzick 2019-08-10T16:33:27Z pathogen_host_interaction_phenotype obsolete pathogen host interaction polysaccharide localization phenotype true PHIPO:0001013 A pathogen host interaction phenotype in which the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037). alaynecuzick 2019-08-10T16:36:54Z pathogen_host_interaction_phenotype obsolete abnormal pathogen host interaction polysaccharide localization true PHIPO:0001014 A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is higher than normal. alaynecuzick 2019-08-10T16:37:53Z increased level of host callose deposition induced by pathogen pathogen_host_interaction_phenotype GO:0052542 increased level of host defense-induced callose deposition PHIPO:0001015 A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is lower than normal. alaynecuzick 2019-08-10T16:38:36Z decreased level of host callose deposition induced by pathogen pathogen_host_interaction_phenotype GO:0052542 decreased level of host defense-induced callose deposition PHIPO:0001016 A pathogen host interaction phenotype where any process in which callose is transported to, and/or maintained in, a specific location during the host defense response to a pathogen is abnormal. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. (GO:0052542). alaynecuzick 2019-08-10T16:43:59Z pathogen_host_interaction_phenotype obsolete altered level of host callose deposition induced by pathogen true PHIPO:0001017 A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is longer than normal. (GO:0032179) alaynecuzick 2019-08-17T12:54:34Z single_species_phenotype long germ tube PHIPO:0001018 A cellular process phenotype in which asexual spore germination is abnormal (GO:0009847). alaynecuzick 2019-08-17T12:59:57Z FYPO:0000305 abnormal conidia germination single_species_phenotype abnormal asexual spore germination PHIPO:0001019 A cellular process phenotype in which the rate, or speed, of asexual spore germination is decreased. alaynecuzick 2019-08-17T13:01:16Z FYPO:0000582 decreased rate of conidia germination single_species_phenotype decreased rate of asexual spore germination PHIPO:0001020 A phenotype in which a population of a single-species shows increased sensitivity to calcofluor white, manifested as an affect on the extent of population growth. (CHEBI:50011) alaynecuzick 2019-08-17T13:35:49Z FYPO:0001188 single_species_phenotype sensitive to calcofluor white PHIPO:0001021 A phenotype in which a population of a single-species shows increased sensitivity to congo red, manifested as an affect on the extent of population growth. (CHEBI:34653). alaynecuzick 2019-08-17T13:36:09Z FYPO:0005984 single_species_phenotype sensitive to congo red PHIPO:0001022 A single species cell phenotype in which the amount of cyclic AMP measured in a cell differs from normal. alaynecuzick 2019-08-17T13:47:08Z FYPO:0001659 abnormal cellular cAMP level altered cellular cyclic AMP level single_species_phenotype altered cellular cAMP level PHIPO:0001023 A single species cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal. alaynecuzick 2019-08-17T13:47:28Z FYPO:0001660 decreased cellular cAMP accumulation reduced cellular cAMP level single_species_phenotype decreased cellular cAMP level PHIPO:0001024 A single species cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal. alaynecuzick 2019-08-17T13:47:39Z FYPO:0001661 increased cAMP accumulation increased cellular cyclic AMP level single_species_phenotype increased cellular cAMP level PHIPO:0001025 A single species cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected. alaynecuzick 2019-08-17T14:21:36Z FYPO:0000834 abnormal protein level altered cellular protein level single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. altered protein level PHIPO:0001026 A single species cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected. alaynecuzick 2019-08-17T14:23:48Z FYPO:0000836 single_species_phenotype increased protein accumulation Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. increased protein level PHIPO:0001027 A single species cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected. alaynecuzick 2019-08-17T14:23:55Z FYPO:0000835 reduced protein level single_species_phenotype decreased protein accumulation Consider annotating to a term describing abnormal translation or abnormal regulation of translation, but note that changes in protein levels may result from changes in protein stability or degradation as well as changes in protein synthesis. decreased protein level PHIPO:0001028 A single organism phenotype in which the localization of a protein to the plasma membrane is abolished (GO:0072659). alaynecuzick 2019-08-17T14:51:09Z single_species_phenotype We recommend noting which protein(s) were used in the assay when annotating to this term. abolished protein localization to plasma membrane PHIPO:0001029 A single organism phenotype in which the localization of a protein to the plasma membrane is abolished, and the protein is present in the cytoplasm instead. alaynecuzick 2019-08-17T14:55:21Z FYPO:0002126 single_species_phenotype We recommend noting which protein(s) were used in the assay when annotating to this term. abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm PHIPO:0001030 A single species cell phenotype in which the amount of toxin measured in a cell differs from normal. alaynecuzick 2019-09-06T10:49:07Z single_species_phenotype altered cellular toxin level PHIPO:0001031 A single species cell phenotype in which the amount of toxin measured in a cell is lower than normal. alaynecuzick 2019-09-06T10:49:58Z single_species_phenotype decreased cellular toxin level PHIPO:0001032 A single species cell phenotype in which the amount of pyocyanin measured in a cell is lower than normal. alaynecuzick 2019-09-06T10:50:37Z single_species_phenotype decreased level of pyocyanin PHIPO:0001033 A single species cell phenotype in which the amount of pyocyanin measured in a cell is too low to detect. alaynecuzick 2019-09-06T10:51:03Z single_species_phenotype pyocyanin absent from cell PHIPO:0001034 A single species cell phenotype in which the amount of a specific substance measured in a cell is too low to detect. alaynecuzick 2019-09-06T11:00:13Z FYPO:0001888 single_species_phenotype substance absent from cell PHIPO:0001035 A single species cell phenotype in which the amount of a specific substance measured in a cell is lower than normal. alaynecuzick 2019-09-06T11:04:53Z FYPO:0000991 reduced level of substance in cell single_species_phenotype decreased level of substance in cell PHIPO:0001036 A single species cell phenotype in which the amount of a specific substance measured in a cell is higher than normal. alaynecuzick 2019-09-06T11:05:35Z FYPO:0000990 single_species_phenotype increased accumulation of substance in cell increased level of substance in cell PHIPO:0001037 A single species cell phenotype in which the amount of toxin measured in a cell is higher than normal. alaynecuzick 2019-09-06T11:24:02Z single_species_phenotype increased cellular toxin level PHIPO:0001038 A single species cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-09-06T11:34:52Z FYPO:0001076 single_species_phenotype normal level of substance in cell PHIPO:0001039 A single species cell phenotype in which the amount of toxin measured in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-09-06T11:55:23Z single_species_phenotype normal cellular toxin level PHIPO:0001040 A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is lower than normal. alaynecuzick 2019-09-06T12:27:07Z pathogen_host_interaction_phenotype obsolete decreased level of a substance in a pathogen host interaction true PHIPO:0001041 A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is higher than normal. alaynecuzick 2019-09-06T12:27:17Z pathogen_host_interaction_phenotype obsolete increased level of a substance in a pathogen host interaction true PHIPO:0001042 A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is too low to detect. alaynecuzick 2019-09-06T12:27:54Z pathogen_host_interaction_phenotype obsolete substance absent in a pathogen host interaction true PHIPO:0001043 A pathogen host interaction phenotype, which affects the level of pathogen produced toxin during host infection. alaynecuzick 2019-09-06T12:30:03Z pathogen_host_interaction_phenotype level of pathogen produced toxin within host phenotype PHIPO:0001044 A cell phenotype in which the amount of protein measured in a pathogen or host cell is too low to detect. Total protein or a specific protein may be affected. alaynecuzick 2019-09-06T12:39:49Z FYPO:0001983 pathogen_host_interaction_phenotype obsolete protein absent in a pathogen host interaction true PHIPO:0001045 A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is lower than normal. alaynecuzick 2019-09-06T12:44:12Z pathogen_host_interaction_phenotype decreased level of pathogen produced toxin within host PHIPO:0001046 A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is higher than normal. alaynecuzick 2019-09-06T12:44:20Z pathogen_host_interaction_phenotype increased level of pathogen produced toxin within host PHIPO:0001047 A pathogen host interaction phenotype, in which the pathogen produced toxin usually present during infection is absent or at a level too low to detect. alaynecuzick 2019-09-06T12:45:24Z pathogen_host_interaction_phenotype absence of pathogen toxin within host pathogen toxin within host absent PHIPO:0001048 A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-09-06T12:46:32Z pathogen_host_interaction_phenotype obsolete normal level of substance phenotype in a pathogen host interaction true PHIPO:0001049 A single species population phenotype affecting the shape of a colony of unicellular individuals. alaynecuzick 2019-09-10T13:26:05Z colony morphology phenotype single_species_phenotype Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. unicellular colony shape phenotype PHIPO:0001051 A single species phenotype where the shape of a colony of unicellular individuals is abnormal. alaynecuzick 2019-09-10T13:29:47Z PHIPO:0001050 abnormal colony morphology single_species_phenotype Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. abnormal unicellular colony shape PHIPO:0001052 A single species colony shape phenotype where the colony is smoother than normal. alaynecuzick 2019-09-10T13:32:18Z single_species_phenotype hyper-smooth colony morphology Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. hyper-smooth unicellular colony shape PHIPO:0001053 A single species phenotype where the shape of a colony of unicellular individuals is more rugose (wrinkled; corrugated) than normal. alaynecuzick 2019-09-10T13:32:45Z single_species_phenotype hyper-rugose colony morphology Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. hyper-rugose unicellular colony shape PHIPO:0001055 A single species colony morphology phenotype where the size of the population is increased. alaynecuzick 2019-09-10T13:37:47Z PHIPO:0000179 single_species_phenotype increased filamentous growth increased size of filamentous colony obsolete increased size of colony true PHIPO:0001057 A single species phenotype where the shape of a colony of unicellular individuals is normal (indistinguishable from wild type). alaynecuzick 2019-09-13T10:53:42Z PHIPO:0001065 normal colony morphology normal shape of colony single_species_phenotype Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. normal unicellular colony shape PHIPO:0001058 A single species phenotype where the shape of a colony of unicellular individuals is as rugose (wrinkled; corrugated) as normal (indistinguishable from wild type). alaynecuzick 2019-09-10T13:40:49Z single_species_phenotype normal rugose colony morphology Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. normal rugose unicellular colony shape PHIPO:0001059 A single species cell phenotype in which the amount of pyocyanin measured in a cell is higher than normal. alaynecuzick 2019-09-11T13:06:36Z single_species_phenotype increased level of pyocyanin PHIPO:0001060 A single species cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-09-11T13:14:54Z FYPO:0000824 abnormal RNA level altered cellular RNA level altered transcript level single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. altered RNA level PHIPO:0001061 A singe species cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-09-11T13:18:59Z FYPO:0000826 decreased cellular RNA level decreased transcript level reduced RNA level single_species_phenotype Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. decreased RNA level PHIPO:0001062 A single species cell phenotype in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-09-11T13:22:53Z FYPO:0001890 increased cellular RNA level increased transcript level single_species_phenotype increased RNA accumulation Consider annotating to a term describing abnormal transcription or abnormal regulation of transcription, but note that changes in RNA levels may result from changes in RNA stability as well as changes in transcription. We recommend noting which RNA(s) were used in the assay when annotating to this term. increased RNA level PHIPO:0001063 A single species cell phenotype in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-09-11T13:26:30Z FYPO:0001889 transcripts absent from cell undetectable cellular RNA level single_species_phenotype RNA absent from cell PHIPO:0001064 A single species cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-09-11T13:30:41Z FYPO:0000840 normal cellular RNA level normal transcript level normal mRNA level single_species_phenotype normal RNA level PHIPO:0001067 A pathogen host interaction phenotype that is observed at the level of an individual organism (eg a worm host). alaynecuzick 2019-09-20T11:03:58Z pathogen_host_interaction_phenotype obsolete pathogen host interaction organism level phenotype true PHIPO:0001068 A host organism viability phenotype where the host organism survives in the presence of the pathogen. alaynecuzick 2019-09-20T11:06:42Z pathogen_host_interaction_phenotype viable host organism with pathogen survival of host organism with pathogen PHIPO:0001069 A host organism viability phenotype where the host organism death is accelerated by the pathogen. alaynecuzick 2019-09-20T11:07:02Z pathogen_host_interaction_phenotype host kill assay inviable host organism with pathogen pathogen induced death of host organism precocious senescence death of host organism with pathogen PHIPO:0001070 A pathogen host interaction organism level phenotype which affects the viability of an individual host organism in the presence of a pathogen. alaynecuzick 2019-09-20T11:19:37Z pathogen_host_interaction_phenotype host organism viability with pathogen phenotype PHIPO:0001071 A pathogen host interaction organism viability phenotype where a host organism is viable in the presence of a pathogen. alaynecuzick 2019-09-20T11:20:10Z pathogen_host_interaction_phenotype obsolete viable host organism with pathogen true PHIPO:0001072 A pathogen host interaction organism viability phenotype where a host organism is inviable in the presence of a pathogen. alaynecuzick 2019-09-20T11:20:25Z pathogen_host_interaction_phenotype obsolete inviable host organism with pathogen true PHIPO:0001074 A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2019-09-27T09:51:47Z FYPO:0002015 hypersensitive to iron ion starvation sensitive to iron ion depletion sensitive to iron ion deprivation sensitive to iron starvation single_species_phenotype sensitive to iron ion starvation PHIPO:0001075 A growth phenotype which describes an individual or a population of organisms which requires a particular organic compound, which is not required by a wild-type for its growth. Auxotrophy usually results from a cell's inability to synthesize the compound. alaynecuzick 2019-09-27T10:01:40Z FYPO:0000128 single_species_phenotype auxotrophy phenotype auxotrophic growth PHIPO:0001076 A growth phenotype which describes an individual or a population of organisms which requires lysine for growth. Auxotrophy usually results from a cell's inability to synthesize the compound. alaynecuzick 2019-09-27T10:02:07Z FYPO:0000039 single_species_phenotype growth auxotrophic for lysine PHIPO:0001077 A single species individual organism phenotype where the accumulation of melanin in a cell is decreased. alaynecuzick 2019-09-27T10:16:39Z single_species_phenotype decreased cellular melanin accumulation PHIPO:0001078 A single species individual organism phenotype where the accumulation of melanin in a cell is absent. alaynecuzick 2019-09-27T10:17:08Z single_species_phenotype albino non-pigmented absence of cellular melanin accumulation PHIPO:0001079 A pathogen host interaction organism level phenotype affecting the deposition or aggregation of coloring matter in a cell. alaynecuzick 2019-09-27T11:17:57Z pathogen_host_interaction_phenotype obsolete pathogen host interaction pigment phenotype true PHIPO:0001080 A pathogen host interaction phenotype, in which the accumulation of pathogen pigmentation (coloring matter) usually present during infection differs from normal. alaynecuzick 2019-09-27T11:19:13Z pathogen_host_interaction_phenotype altered pathogen pigment accumulation within host PHIPO:0001081 A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is absent. alaynecuzick 2019-09-27T11:20:21Z absence of melanin accumulation in pathogen conidia with host pathogen_host_interaction_phenotype absence of melanin accumulation in pathogen asexual spore within host PHIPO:0001083 A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-10-01T09:09:20Z pathogen induced callose deposition in host present pathogen-induced callose deposition in host present pathogen_host_interaction_phenotype presence of pathogen induced callose deposition in host GO:0052542 host defense-induced callose deposition present PHIPO:0001084 A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is faster than normal. alaynecuzick 2019-10-01T09:17:27Z FYPO:0000636 single_species_phenotype increased unicellular population growth rate PHIPO:0001085 A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is slower than normal. alaynecuzick 2019-10-01T09:21:13Z FYPO:0001355 single_species_phenotype decreased unicellular population growth rate PHIPO:0001086 A single species cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal. alaynecuzick 2019-10-01T09:36:55Z FYPO:0000336 single_species_phenotype abnormal cellular component assembly PHIPO:0001088 An individual organism growth phenotype in which the rate, or speed, of hyphae formation is decreased. alaynecuzick 2019-10-01T09:41:16Z slow hyphae formation single_species_phenotype decreased rate of hyphae formation PHIPO:0001089 An individual organism growth phenotype in which the rate, or speed, of germ tube formation is decreased resulting in decreased hyphal growth. alaynecuzick 2019-10-01T09:42:41Z slow germination tube formation single_species_phenotype decreased rate of germination tube formation PHIPO:0001090 A single organism localization phenotype in which a protein is not exported via the secretory pathway. alaynecuzick 2019-10-01T09:56:51Z single_species_phenotype abolished protein secretion PHIPO:0001091 A single species molecular function phenotype in which a chitinase activity is absent. alaynecuzick 2019-10-01T13:15:29Z chitinase activity absent single_species_phenotype abolished chitinase activity PHIPO:0001092 A single species cell phenotype in which the amount of chitin measured in the spore is higher than normal alaynecuzick 2019-10-01T13:26:59Z increased chitin level in conidia single_species_phenotype increased chitin level in asexual spore PHIPO:0001094 A single species phenotype where the localization of a structure or substance in a cell is abnormal. alaynecuzick 2019-10-01T13:35:05Z single_species_phenotype abnormal localization PHIPO:0001095 A single organism phenotype in which the localization of chitin in a cell is abnormal. Chitin may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. alaynecuzick 2019-10-01T13:37:30Z abnormal chitin distribution abnormal chitin deposition single_species_phenotype abnormal localization of chitin in cell PHIPO:0001096 A growth phenotype which describes the resistance of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2019-10-04T09:18:07Z FYPO:0002046 resistant to stress stress resistance: increased single_species_phenotype resistance to stress PHIPO:0001097 A growth phenotype which describes the resistance of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2019-10-04T09:18:26Z single_species_phenotype resistance to cell wall stress PHIPO:0001098 A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2019-10-04T09:25:47Z PHIPO:0001073 FYPO:0000304 FYPO:0002549 hypersensitive to stress stress resistance: decreased single_species_phenotype sensitive to stress during growth sensitive to stress PHIPO:0001099 A cell phenotype in which the amount of RNA measured in a pathogen or host cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. alaynecuzick 2019-10-04T12:30:49Z pathogen_host_interaction_phenotype obsolete increased RNA level in a pathogen host interaction true PHIPO:0001100 A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is higher than normal. alaynecuzick 2019-10-04T12:31:14Z pathogen_host_interaction_phenotype increased level of pathogen RNA within host PHIPO:0001101 A pathogen reproductive phenotype within host where the pathogen asexual sporulation structures are absent. alaynecuzick 2019-10-04T12:39:32Z pathogen_host_interaction_phenotype pycnidia absent within host absence of pathogen asexual sporulation structures within host PHIPO:0001102 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is normal (i.e. indistinguishable from wild type). alaynecuzick 2019-10-04T12:43:45Z pathogen_host_interaction_phenotype normal number of pycnidia within host presence of pathogen asexual sporulation structures within host lesion PHIPO:0001104 A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is higher than normal. alaynecuzick 2019-10-07T13:26:33Z increased level of host RNA involved in a pathogen interaction pathogen_host_interaction_phenotype increased level of host defense-induced RNA PHIPO:0001105 A single species cell phenotype in which the amount of gliotoxin measured in a cell is too low to detect. alaynecuzick 2019-10-07T13:29:01Z single_species_phenotype gliotoxin absent from cell PHIPO:0001106 A molecular function phenotype in which the binding of one pathogen protein to one host protein is present. alaynecuzick 2019-10-09T12:33:57Z binding present between pathogen protein and host protein pathogen_host_interaction_phenotype presence of pathogen host protein-protein interaction PHIPO:0001107 A molecular function phenotype in which the binding of one pathogen protein to one host protein is absent. alaynecuzick 2018-10-01T13:31:59Z PHIPO:0000204 binding absent between pathogen protein and host protein pathogen_host_interaction_phenotype abolished pathogen host protein-protein interaction absence of pathogen host protein-protein interaction PHIPO:0001108 A pathogen host interaction phenotype that affects the pH in a pathogen or host cell or cellular component. alaynecuzick 2019-10-09T12:41:35Z pathogen_host_interaction_phenotype Note that this term was reinstated from obsolete. pathogen host interaction pH phenotype PHIPO:0001109 A pathogen host interaction phenotype, in which the host pH value during infection differs from normal. alaynecuzick 2019-10-09T12:42:06Z abnormal pathogen induced host pH altered pathogen induced host pH pathogen_host_interaction_phenotype obsolete abnormal pathogen-induced host pH true PHIPO:0001110 A pathogen host interaction phenotype where the pathogen induces a pH decrease within the host cell or cellular component. alaynecuzick 2019-10-09T12:42:51Z pathogen induced acidification of host pathogen induced decrease in host pH pathogen induced low pH in host pathogen_host_interaction_phenotype obsolete pathogen-induced decrease in host pH true PHIPO:0001111 A pathogen host interaction phenotype where the pathogen induces a pH increase within the host cell or cellular component. alaynecuzick 2019-10-09T12:43:07Z pathogen induced alkalinization of host pathogen induced high pH in host pathogen induced increase in host pH pathogen_host_interaction_phenotype obsolete pathogen-induced increase in host pH true PHIPO:0001112 A pathogen host interaction phenotype where the pH in a pathogen or host cell or cellular component is normal. alaynecuzick 2019-10-09T12:45:38Z pathogen_host_interaction_phenotype obsolete normal pH within a pathogen host interaction true PHIPO:0001113 A pathogen host interaction phenotype where the host induces a pH decrease within the host phagolysome in response to pathogen colonization. alaynecuzick 2019-10-09T12:49:07Z pathogen induced acidification in host phagolysome pathogen induced pH decrease in host phagolysome pathogen_host_interaction_phenotype host defense induced acidification in phagolysome present PHIPO:0001114 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is fewer than normal. alaynecuzick 2019-10-11T10:55:28Z pathogen_host_interaction_phenotype reduced number of pycnidia within host decreased number of pathogen asexual sporulation structures within host lesion PHIPO:0001115 A single species molecular function phenotype in which the observed rate of phosphopantetheinyl transferase activity is decreased. alaynecuzick 2019-10-18T09:13:50Z single_species_phenotype decreased phosphopantetheinyl transferase activity PHIPO:0001116 A pathogen host interaction phenotype that affects a host immune system signaling pathway during pathogen infection. alaynecuzick 2019-10-22T12:26:26Z pathogen_host_interaction_phenotype pathogen modulation of host immune system signaling pathway phenotype host immune system signaling pathway pathogen-host interaction phenotype PHIPO:0001117 A pathogen host interaction phenotype, in which the host immune signaling pathway is induced by a pathogen. alaynecuzick 2019-10-22T12:26:58Z host immune signalling pathway activated by pathogen pathogen_host_interaction_phenotype host immune signaling pathway activated by pathogen PHIPO:0001118 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. alaynecuzick 2019-11-06T13:01:27Z FYPO:0000329 single_species_phenotype abnormal protein modification PHIPO:0001119 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal. alaynecuzick 2019-11-06T13:02:19Z FYPO:0000775 single_species_phenotype abnormal protein phosphorylation PHIPO:0001120 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. alaynecuzick 2019-11-06T13:02:53Z FYPO:0001838 single_species_phenotype decreased protein phosphorylation PHIPO:0001121 A single species phenotype where the sexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608). alaynecuzick 2019-11-06T13:43:30Z single_species_phenotype abnormal sexual reproductive structure development PHIPO:0001122 A single species reproductive phenotype in which the frequency of occurrence of sexual sporulation structures is fewer than normal. alaynecuzick 2019-11-06T13:45:40Z single_species_phenotype decreased perithecium formation decreased number of sexual sporulation structures PHIPO:0001123 An organism population phenotype in which some organisms in the population are viable. alaynecuzick 2019-12-03T10:47:11Z non-lethal single_species_phenotype non-essential viable population PHIPO:0001124 A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing erucic acid as the carbon source. alaynecuzick 2019-12-03T10:52:30Z single_species_phenotype decreased growth on erucic acid carbon source PHIPO:0001125 A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing oleic acid as the carbon source. alaynecuzick 2019-12-03T10:57:47Z single_species_phenotype decreased growth on oleic acid carbon source PHIPO:0001126 A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing palmitic acid as the carbon source. alaynecuzick 2019-12-03T10:58:27Z single_species_phenotype decreased growth on palmitic acid carbon source PHIPO:0001127 A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing myristic acid as the carbon source. alaynecuzick 2019-12-03T10:59:32Z single_species_phenotype decreased growth on myristic acid carbon source PHIPO:0001128 A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is suppressed by a pathogen. (GO:0052034) alaynecuzick 2019-12-03T11:08:34Z pathogen suppression of host PAMP-triggered immunity suppression of host MAMP-triggered immunity suppression of host PAMP-triggered immunity suppression of host PTI pathogen_host_interaction_phenotype effector-mediated suppression of host PAMP-triggered immunity present PHIPO:0001130 A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased size of the host organism. alaynecuzick 2019-12-09T13:45:59Z decreased host growth with pathogen decreased host size with pathogen pathogen_host_interaction_phenotype stunted host growth during pathogen colonization PHIPO:0001131 A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of side shoots produced by the host organism. alaynecuzick 2019-12-09T13:51:02Z increased number of host tillers during pathogen colonization pathogen_host_interaction_phenotype increased number of host side shoots during pathogen colonization PHIPO:0001132 A pathogen host interaction phenotype where the size of the pathogen vacuoles are larger than normal during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. alaynecuzick 2019-12-09T14:04:10Z pathogen_host_interaction_phenotype increased size of pathogen vacuoles during host colonization PHIPO:0001133 A single species individual organism phenotype where the accumulation of melanin in a cell is increased. alaynecuzick 2019-12-17T14:27:14Z single_species_phenotype increased cellular melanin accumulation PHIPO:0001134 A growth phenotype which describes the sensitivity of individuals or populations after exposure to potassium chloride. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2019-12-17T14:30:47Z FYPO:0001214 single_species_phenotype sensitive to potassium chloride PHIPO:0001135 A growth phenotype which describes the sensitivity of individuals or populations after exposure to sorbitol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2019-12-17T14:32:35Z FYPO:0000112 single_species_phenotype sensitive to sorbitol PHIPO:0001136 A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abolished (it was present and is now absent) (GO:0048608). alaynecuzick 2019-12-18T09:31:20Z abolished development of conidiophore single_species_phenotype abolished development of asexual reproductive structure PHIPO:0001137 An individual organism cellular process phenotype in which the number of septa produced during hyphae formation is increased. alaynecuzick 2019-12-18T09:34:09Z single_species_phenotype This phenotype is related to division rather than growth and usually indicates that hyphae with more septa have an increased number of smaller individual cells. If experiments also indicate an increase or reduction in hyphal growth please coannotate in the hyphal growth branch. increased number of hyphal septa PHIPO:0001138 A single species phenotype where the frequency of occurrence of asexual reproductive structures is decreased. alaynecuzick 2019-12-19T09:51:13Z decreased number of conidiophores single_species_phenotype decreased number of asexual reproductive structures PHIPO:0001139 A single species phenotype where the frequency of occurrence of septum within an asexual spore is decreased. alaynecuzick 2020-01-07T13:11:13Z decreased number of conidial septum decreased number of septum in conidia single_species_phenotype decreased number of septum in asexual spore PHIPO:0001140 A cell signaling pathway phenotype where the host pattern recognition receptor signaling pathway is directly induced by a pathogen. This can include any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to a pathogen-derived physiological ligand. PRR ligands are usually referred to as pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), structures conserved among microbial species (GO:0002221). alaynecuzick 2020-01-28T11:29:52Z activation of host PRR signalling pathway activation of host MAMP-triggered immunity signaling activation of host PAMP-triggered immunity signaling activation of host PTI signaling host PAMP-triggered immunity signalling activated by pathogen host PTI signaling activated by pathogen pathogen_host_interaction_phenotype pathogen induced host MAP kinase activity host PAMP-triggered immunity signaling activated by pathogen present PHIPO:0001141 A cell signaling pathway phenotype where the host effector-triggered immunity signaling pathway is induced by a pathogen to activate a plant hypersensitive response and induce necrosis. alaynecuzick 2020-01-28T11:36:13Z activation of host ETI activation of host ETI inducing PCD activation of host ETI inducing HR activation of host ETI signalling pathway inducing HR activation of host effector-triggered immunity inducing HR host ETI signalling induced HR activated by pathogen host effector triggered immunity signalling induced hypersensitive response activated by pathogen pathogen_host_interaction_phenotype obsolete host effector triggered immunity signaling induced hypersensitive response activated by pathogen true PHIPO:0001142 A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is normal (i.e. indistinguishable from wild type). alaynecuzick 2020-01-28T12:05:46Z pathogen_host_interaction_phenotype normal pathogen protein localization to host chloroplast PHIPO:0001143 A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is abolished (i.e.the protein was localized to the host chloroplast and now is not). alaynecuzick 2020-01-28T12:13:25Z pathogen_host_interaction_phenotype abolished pathogen protein localization to host chloroplast PHIPO:0001144 A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is lower than normal. alaynecuzick 2020-01-28T12:40:16Z decreased level of host defense related RNA involved in a pathogen interaction pathogen_host_interaction_phenotype decreased level of host defense-related RNA involved in a pathogen interaction PHIPO:0001145 A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently suppressed by a pathogen effector. alaynecuzick 2020-03-04T12:47:38Z pathogen suppression of host ETI pathogen suppression of host effector triggered immunity suppression of host ETI suppression of host effector triggered immunity pathogen_host_interaction_phenotype effector-mediated suppression of host effector triggered immunity present PHIPO:0001147 A single organism phenotype that affects the chemical reactions and pathways by which individual cells transform chemical substances. (GO:0044237) alaynecuzick 2020-03-04T13:53:21Z cellular metabolism phenotype single_species_phenotype cellular metabolic process phenotype PHIPO:0001148 A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is unaltered.(GO:1903409) alaynecuzick 2020-03-04T13:57:18Z normal ROS production normal reactive oxygen species production unaltered ROS production single_species_phenotype unaltered reactive oxygen species production PHIPO:0001149 A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is decreased.(GO:1903409) alaynecuzick 2020-03-04T14:03:31Z decreased ROS production decreased reactive oxygen species production reduced ROS production reduced reactive oxygen species production single_species_phenotype decreased reactive oxygen species production PHIPO:0001150 A single species localization phenotype in which ROS are produced over a different portion of the cell than normal. alaynecuzick 2020-03-04T14:11:20Z abnormal spatial extent of ROS production single_species_phenotype abnormal spatial extent of reactive oxygen species production PHIPO:0001151 A host morphology phenotype where the size of the host is normal (indistinguishable from wild type) during pathogen invasion. alaynecuzick 2020-03-04T14:21:48Z pathogen_host_interaction_phenotype normal host size during pathogen invasion PHIPO:0001152 A pathogen host interaction phenotype where the morphology of the host plasma membrane has increased blebbing during pathogen invasion. alaynecuzick 2020-03-04T14:27:03Z increased host membrane blebbing during symbiont invasion pathogen_host_interaction_phenotype increased host membrane blebbing during pathogen invasion PHIPO:0001153 A single species cell morphology phenotype in which fungal hyphae form an increased number of branches. alaynecuzick 2020-03-04T14:33:49Z increased branching of hyphae increased hyphal branching single_species_phenotype hyphal hyper branching PHIPO:0001154 A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product is decreased. alaynecuzick 2020-03-10T09:51:20Z single_species_phenotype decreased pathogen chitin fragment binding PHIPO:0001155 A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is lower than normal. alaynecuzick 2020-03-10T11:33:08Z decreased level of pathogen ROS production with host pathogen_host_interaction_phenotype decreased level of pathogen reactive oxygen species production within host PHIPO:0001156 A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is higher than normal. alaynecuzick 2020-03-10T11:35:08Z increased level of pathogen ROS production with host pathogen_host_interaction_phenotype increased level of pathogen reactive oxygen species production within host PHIPO:0001157 A pathogen host interaction metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) by the pathogen is unaltered within the host.(GO:1903409) alaynecuzick 2020-03-10T11:35:41Z normal pathogen ROS production within host pathogen_host_interaction_phenotype obsolete unaltered pathogen reactive oxygen species production within host true PHIPO:0001159 A pathogen host interaction colonization phenotype which affects the directional tissue to tissue movement of the pathogen within the host organism (GO:0044001). alaynecuzick 2020-03-27T18:25:20Z pathogen_host_interaction_phenotype pathogen tissue to tissue migration within host phenotype PHIPO:0001160 A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is abolished (pathogen migration was present within the host and is now absent). alaynecuzick 2020-03-27T18:30:00Z pathogen_host_interaction_phenotype abolished pathogen tissue to tissue migration within host PHIPO:0001161 A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are absent or at a level too low to detect. alaynecuzick 2020-03-27T18:36:56Z pathogen induced host phenolic compound absent pathogen-induced host phenolic compound absent pathogen_host_interaction_phenotype absence of pathogen induced host phenolic compound decreased level of CHEBI:33853 in host during GO:051702 interaction with symbiont host defense-induced phenolic compound absent PHIPO:0001162 A pathogen host interaction phenotype which affects the host reproductive process within the host when a pathogen is present. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). alaynecuzick 2020-03-30T15:14:51Z pathogen_host_interaction_phenotype obsolete host reproductive phenotype induced by pathogen true PHIPO:0001163 A pathogen host interaction phenotype which affects either the pathogen or host reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). alaynecuzick 2020-03-30T15:16:04Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. obsolete pathogen host interaction reproductive phenotype true PHIPO:0001164 A host reproductive phenotype with pathogen where the process of host reproductive development is abnormal (GO:0048608). alaynecuzick 2020-03-30T15:17:25Z pathogen_host_interaction_phenotype obsolete abnormal host reproductive structure development induced by pathogen true PHIPO:0001165 A host reproductive phenotype with pathogen where the process of host seed development is abnormal (GO:0048316). alaynecuzick 2020-03-30T15:17:44Z abnormal host grain development with pathogen pathogen_host_interaction_phenotype abnormal host seed development induced by pathogen PHIPO:0001166 A host reproductive phenotype with pathogen where the process of host seed development is absent (GO:0048316). alaynecuzick 2020-03-30T15:18:09Z host grain development absent with pathogen pathogen_host_interaction_phenotype absence of host seed development induced by pathogen PHIPO:0001167 A pathogen host interaction phenotype that affects a host immune system process during pathogen infection (GO:0002376). alaynecuzick 2020-04-27T16:23:38Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate This is a high-level term whose primary purpose is to organize terms beneath it in the ontology, and we expect that it will not be used for direct annotations. Please consider using a more specific term to annotate each phenotype. pathogen modulation of host immune system process phenotype PHIPO:0001168 A pathogen host interaction phenotype, in which the host immune response protease activity is inhibited by the pathogen. alaynecuzick 2020-04-27T16:38:17Z inhibition of host immune response serine-type peptidase activity present pathogen_host_interaction_phenotype presence of pathogen inhibition of host immune response protease PHIPO:0001173 A pathogen host interaction phenotype, in which a pathogen effects a change in the structure or processes of its host organism (GO:0044003). alaynecuzick 2020-05-12T11:06:22Z pathogen_host_interaction_phenotype pathogen modulation of host process phenotype PHIPO:0001174 A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is lower than normal. alaynecuzick 2020-05-12T13:21:58Z decreased level of host RNA involved in a pathogen interaction pathogen_host_interaction_phenotype decreased level of host defense-induced RNA PHIPO:0001175 A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell is normal. alaynecuzick 2020-05-13T13:50:08Z pathogen_host_interaction_phenotype normal pathogen protein localization within host PHIPO:0001176 A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. alaynecuzick 2020-05-13T15:00:47Z pathogen_host_interaction_phenotype effector-mediated immune suppression phenotype PHIPO:0001179 A pathogen host interaction phenotype that affects the infective ability of a pathogen during attempted colonization of a host. alaynecuzick 2020-06-01T13:19:23Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate For use in the annotation extension infective ability. infective ability phenotype PHIPO:0001180 A single species phenotype where the immune system process of host tissue hypersensitive response is absent in a pathogen effector-independant manner. (i.e. an alteration within the host does not activate the hypersensitive response in the absence of a pathogen). alaynecuzick 2020-06-09T11:25:32Z PHIPO:0001181 single_species_phenotype abolished effector-independent host hypersensitive response host_phenotype absence of effector-independent host hypersensitive response PHIPO:0001182 A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2020-06-10T15:09:01Z normal level of DON normal level of vomitoxin single_species_phenotype normal level of deoxynivalenol PHIPO:0001183 A phenotype that is relevant to host resistance to a given pathogen. alaynecuzick 2020-06-22T15:25:30Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate obsolete host resistance to pathogen phenotype true PHIPO:0001184 A phenotype where the ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is abolished (resistance was present and is now absent). alaynecuzick 2020-06-22T15:26:41Z loss of host resistance pathogen_host_interaction_phenotype qc_do_not_annotate obsolete loss of functional host resistance gene true PHIPO:0001185 A phenotype where the ability of a host, to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is acquired (resistance was absent and is now present). alaynecuzick 2020-06-22T15:26:51Z gain of host resistance pathogen_host_interaction_phenotype qc_do_not_annotate Gain of function may result from engineering of a natural variant or transformation obsolete gain of functional host resistance gene true PHIPO:0001186 A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is present. alaynecuzick 2020-06-22T15:27:22Z host resistance present host susceptibility absent pathogen_host_interaction_phenotype qc_do_not_annotate obsolete functional host resistance gene present true PHIPO:0001187 A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is absent. alaynecuzick 2020-06-22T15:27:41Z host resistance absent host susceptibility present pathogen_host_interaction_phenotype qc_do_not_annotate obsolete functional host resistance gene absent true PHIPO:0001188 A pathogen host interaction phenotype that affects the outcome of a gene-for-gene relationship in plant pathogen interactions. The gene-for-gene hypothesis follows that for each gene controlling resistance (R) in the host there is a corresponding gene controlling avirulence (avr) in the pathogen. alaynecuzick 2020-06-23T10:48:16Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate For use in the annotation extension gene-for-gene interaction. obsolete gene-for-gene interaction phenotype true PHIPO:0001189 A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease susceptibility. alaynecuzick 2020-06-23T10:49:18Z pathogen_host_interaction_phenotype qc_extension_only obsolete compatible interaction true PHIPO:0001190 A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease resistance. alaynecuzick 2020-06-23T10:49:48Z pathogen_host_interaction_phenotype qc_extension_only obsolete incompatible interaction true PHIPO:0001191 A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is present. alaynecuzick 2020-07-20T11:19:37Z presence of melanin accumulation in pathogen conidia with host pathogen_host_interaction_phenotype presence of melanin accumulation in pathogen asexual spore within host PHIPO:0001192 A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is lower than normal. alaynecuzick 2020-07-31T09:49:14Z decreased level of pathogen induced host ROS decreased level of pathogen induced host reactive oxygen species decreased level of pathogen-induced host ROS decreased level of pathogen-induced host reactive oxygen species decreased pathogen host interaction oxidative burst decreased pathogen host interaction respiratory burst pathogen_host_interaction_phenotype decreased level of host defense-induced reactive oxygen species PHIPO:0001193 A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is higher than normal. alaynecuzick 2020-07-31T09:49:30Z increased level of pathogen induced host reactive oxygen species increased level of pathogen-induced host reactive oxygen species increased pathogen host interaction oxidative burst increased pathogen host interaction respiratory burst pathogen_host_interaction_phenotype increased level of host defense-induced reactive oxygen species PHIPO:0001194 A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is absent. alaynecuzick 2020-07-31T15:28:52Z pathogen_host_interaction_phenotype inhibition of pathogen chorismate mutase by host absent PHIPO:0001195 A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is present. alaynecuzick 2020-07-31T15:29:07Z pathogen_host_interaction_phenotype inhibition of pathogen chorismate mutase by host present PHIPO:0001196 A pathogen host interaction phenotype, which affects the level of a host produced substance during infection. alaynecuzick 2020-08-03T15:04:15Z PHIPO:0001169 PHIPO:0001172 pathogen induced host substance level phenotype pathogen-induced host substance level phenotype pathogen_host_interaction_phenotype host defense-induced substance level phenotype PHIPO:0001197 A pathogen host interaction phenotype, which affects the level of a pathogen produced substance during host infection. alaynecuzick 2020-08-03T15:40:26Z PHIPO:0001170 PHIPO:0001171 pathogen_host_interaction_phenotype level of pathogen produced substance within host phenotype PHIPO:0001198 A pathogen host interaction phenotype that affects the disease outcome of a pathogen host interaction. alaynecuzick 2020-09-14T12:39:58Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate For use in the annotation extension outcome of interaction. outcome of interaction phenotype PHIPO:0001199 A pathogen host interaction phenotype where disease is absent. alaynecuzick 2020-09-14T12:42:47Z pathogen_host_interaction_phenotype qc_extension_only disease absent PHIPO:0001200 A pathogen host interaction phenotype where disease is present. alaynecuzick 2020-09-14T12:42:57Z pathogen_host_interaction_phenotype qc_extension_only disease present PHIPO:0001201 A phenotype that is relevant to pathogen effectors. alaynecuzick 2020-09-28T12:53:46Z pathogen_host_interaction_phenotype qc_do_not_annotate qc_do_not_manually_annotate obsolete pathogen effector phenotype true PHIPO:0001202 A phenotype where the ability of a pathogen effector to produce an infectious disease is abolished. alaynecuzick 2020-09-29T08:11:20Z pathogen_host_interaction_phenotype qc_do_not_annotate obsolete loss of functional pathogen effector true PHIPO:0001203 A phenotype where the ability of a pathogen effector to produce an infectious disease is acquired. alaynecuzick 2020-09-29T08:11:34Z pathogen_host_interaction_phenotype qc_do_not_annotate obsolete gain of functional pathogen effector true PHIPO:0001204 A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense to a lesser extent than normal. alaynecuzick 2020-10-14T10:36:53Z pathogen_host_interaction_phenotype decreased extent of effector-mediated host hypersensitive response during biotrophy This term is to be used for host protection against the pathogen. decreased extent of host-defense induced lesion by host hypersensitive response PHIPO:0001205 A single species phenotype where the morphology of a cell is abnormal. alaynecuzick 2020-11-13T10:05:01Z single_species_phenotype abnormal filament morphology PHIPO:0001206 A single species phenotype where the morphology of a cell is normal (i.e. indistinguishable from wild type). alaynecuzick 2020-11-13T10:05:12Z single_species_phenotype normal filament morphology PHIPO:0001207 A single species cell morphology phenotype where the length of hyphal filaments are normal (i.e. indistinguishable from wild type). alaynecuzick 2020-11-13T10:05:35Z single_species_phenotype normal filament length PHIPO:0001208 A single species population phenotype affecting the morphology of a colony of unicellular individuals. alaynecuzick 2020-11-16T12:31:56Z single_species_phenotype Note that colony morphology terms are not used in PHIPO to annotate filamentous-form colonies because these phenotypes can be related to specific growth terms for hyphal colony morphology please search for PHIPO:0001214 (hyphal growth phenotype). For unicellular colony morphology at the usual resolution it is usually not possible to make any statement about an individual. For dimorphic pathogens these terms are suitable for yeast-form colony phenotypes. unicellular colony morphology phenotype PHIPO:0001210 An individual organism growth phenotype in which the size or extent of directional growth of hyphae is normal. alaynecuzick 2018-10-03T13:40:03Z PHIPO:0000278 PHIPO:0000960 PHIPO:0000963 PHIPO:0001066 PHIPO:0001211 normal colony morphology normal hyphal colony morphology normal filament formation normal filament growth normal filamentous formation normal hyphae formation single_species_phenotype normal colony morphology normal filament formation normal filamentous formation normal hyphae formation normal hyphal colony morphology normal hyphal colony shape normal population growth during dimorphic hyphal-form normal size of filamentous colony Although this phenotype is for an individual it can be inferred from a population in a colony. normal hyphal growth PHIPO:0001212 An individual organism growth phenotype in which the growth of hyphae is decreased. alaynecuzick 2020-11-17T10:05:15Z PHIPO:0000181 PHIPO:0001056 PHIPO:0001146 decreased filament growth reduced filament growth reduced hyphal growth single_species_phenotype decreased filamentous growth decreased size of colony decreased size of filamentous colony Although this phenotype is for an individual it can be inferred from a population in a colony. decreased hyphal growth PHIPO:0001213 An individual organism growth phenotype in which the growth of hyphae is abolished (it was present and is now absent). alaynecuzick 2020-11-17T10:05:33Z abolished filament growth single_species_phenotype Although this phenotype is for an individual it can be inferred from a population in a colony. abolished hyphal growth PHIPO:0001214 A single species growth phenotype which affects or involves normal or abnormal size, extent or rate of directional growth of the hyphae of an individual organism. alaynecuzick 2018-10-03T13:38:13Z PHIPO:0000273 PHIPO:0001209 filamentous growth phenotype single_species_phenotype filamentous colony morphology phenotype filamentous colony shape phenotype hyphal colony size phenotype qc_do_not_annotate qc_do_not_manually_annotate hyphal growth phenotype PHIPO:0001215 An individual organism growth phenotype in which the size or extent of directional growth of hyphae is abnormal. alaynecuzick 2019-06-10T09:31:25Z PHIPO:0000037 PHIPO:0000957 PHIPO:0000958 PHIPO:0001054 PHIPO:0001087 abnormal colony morphology abnormal hyphal colony morphology single_species_phenotype abnormal filament formation abnormal hyphal colony morphology abnormal hyphal formation abnormal shape of hyphal colony abnormal size of filamentous colony abnormal size of hyphal colony Although this phenotype is for an individual it can be inferred from a population in a colony. abnormal hyphal growth PHIPO:0001216 A growth phenotype which describes the change or absence of change of individuals or populations (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. alaynecuzick 2020-12-02T13:30:45Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate nutrient phenotype PHIPO:0001217 A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific stress. alaynecuzick 2020-12-02T14:07:43Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate stress phenotype PHIPO:0001218 A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific chemical. alaynecuzick 2020-12-02T14:15:52Z single_species_phenotype qc_do_not_annotate qc_do_not_manually_annotate chemical phenotype PHIPO:0001219 A growth phenotype which describes the absence of change of individuals or populations after exposure to voriconazole (i.e. indistinguishable from wild type). alaynecuzick 2020-12-08T15:43:45Z single_species_phenotype normal growth on voriconazole PHIPO:0001220 A phenotype that affects any physical object quality, such as morphology, number, location, etc., of an individual, tissue, cell, or cellular component. alaynecuzick 2020-12-14T11:23:05Z single_species_phenotype physical quality phenotype PHIPO:0001221 A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is abnormal in the vegetative growth phase of the life cycle. alaynecuzick 2020-12-14T11:24:41Z single_species_phenotype abnormal anatomical structure physical quality phenotype PHIPO:0001222 A single species cell phenotype that consists of the cell's disposition to survive and develop normally. alaynecuzick 2020-12-14T14:02:19Z FYPO:0000004 single_species_phenotype cell viability phenotype PHIPO:0001223 A single species phenotype where the morphology of an organism is normal (i.e. indistinguishable from wild type). alaynecuzick 2021-01-25T15:24:55Z single_species_phenotype normal organism morphology PHIPO:0001224 A single species metabolic cellular process phenotype, in which the occurrence of a pathogen effector preventing the hydrolysis of chitin by chitinases is decreased (chitin hydrolysis is increased). alaynecuzick 2021-01-26T14:18:49Z single_species_phenotype decreased PAMP receptor decoy activity increased chitin hydrolysis present PHIPO:0001225 A single species metabolic cellular process phenotype, in which a pathogen effector does not prevent the hydrolysis of chitin by chitinases. alaynecuzick 2021-01-26T14:26:23Z single_species_phenotype PAMP receptor decoy activity absent abolished PAMP receptor decoy activity chitin hydrolysis present PHIPO:0001226 A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is lower than normal. alaynecuzick 2021-02-09T09:16:39Z decreased level of host reducing sugar in apoplast induced by pathogen pathogen_host_interaction_phenotype decreased level of host defense-induced reducing sugar in apoplast PHIPO:0001227 A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is higher than normal. alaynecuzick 2021-02-09T09:16:56Z increased level of host reducing sugar in apoplast induced by pathogen pathogen_host_interaction_phenotype increased level of host defense-induced reducing sugar in apoplast PHIPO:0001228 A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is present as normal (i.e. indistinguishable from wild type). alaynecuzick 2021-02-09T09:27:11Z pathogen ROS production within host present pathogen_host_interaction_phenotype pathogen reactive oxygen species production within host present PHIPO:0001229 A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is present. alaynecuzick 2021-02-11T14:35:06Z pathogen_host_interaction_phenotype presence of pathogen tissue to tissue migration within host PHIPO:0001230 A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are normal (i.e. indistinguishable from wild type). alaynecuzick 2021-02-11T14:46:42Z pathogen-induced host phenolic compound present pathogen_host_interaction_phenotype host defense-induced phenolic compound present PHIPO:0001231 A pathogen host interaction phenotype, in which the host RNA usually present during infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2021-03-02T14:55:22Z host RNA involved in a pathogen interaction present pathogen_host_interaction_phenotype host defense-induced RNA present PHIPO:0001232 A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during host infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2021-03-08T09:26:06Z pathogen_host_interaction_phenotype pathogen RNA within host present PHIPO:0001233 A pathogen host interaction phenotype where the host induced pH decrease within the host phagolysome in response to pathogen colonization is inhibited. alaynecuzick 2021-03-08T13:21:14Z pathogen_host_interaction_phenotype pathogen inhibition of host defense induced acidification in phagolysome PHIPO:0001234 An individual organism growth phenotype in which the growth of hyphae is increased. alaynecuzick 2021-03-10T09:49:03Z increased filament growth increased hyphal growth single_species_phenotype increased filamentous growth increased size of colony increased size of filamentous colony Although this phenotype is for an individual it can be inferred from a population in a colony. increased hyphal growth PHIPO:0001235 A pathogen host interaction phenotype, in which the host defense-related RNA usually present during infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2021-03-16T16:30:04Z pathogen_host_interaction_phenotype host defense-related RNA involved in a pathogen interaction present PHIPO:0001236 A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently not suppressed by a pathogen effector. alaynecuzick 2021-03-22T16:02:47Z effector-mediated suppression of host ETI absent pathogen_host_interaction_phenotype effector-mediated suppression of host effector triggered immunity absent PHIPO:0001237 A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is not suppressed by a pathogen. (GO:0052034) alaynecuzick 2019-12-03T11:09:29Z PHIPO:0001129 abolished pathogen suppression of host PTI abolished suppression of host MAMP-triggered immunity abolished suppression of host PAMP-triggered immunity abolished suppression of host PTI effector-mediated suppression of host PTI absent suppression of host MAMP-triggered immunity absent abolished pathogen suppression of host PAMP-triggered immunity abolished pathogen suppression of host PTI abolished suppression of host MAMP-triggered immunity abolished suppression of host PAMP-triggered immunity abolished suppression of host PTI pathogen_host_interaction_phenotype effector-mediated suppression of host PAMP-triggered immunity absent PHIPO:0001238 A single species molecular function phenotype in which the observed rate of chitinase activity is increased. alaynecuzick 2021-03-23T10:32:17Z single_species_phenotype increased chitinase activity PHIPO:0001239 A pathogen host interaction phenotype where the host induced pH increase in response to pathogen colonization is inhibited. alaynecuzick 2021-03-23T11:00:52Z pathogen_host_interaction_phenotype pathogen inhibition of host defense induced alkalization PHIPO:0001240 A pathogen host interaction phenotype where the host induces a pH increase in response to pathogen colonization. alaynecuzick 2021-03-23T11:03:17Z pathogen_host_interaction_phenotype host defense induced alkalization present PHIPO:0001241 A single species molecular function phenotype in which the observed rate of chitinase activity is decreased. alaynecuzick 2021-03-23T11:09:16Z single_species_phenotype decreased chitinase activity PHIPO:0001242 A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is present. alaynecuzick 2021-03-23T11:17:39Z pathogen_host_interaction_phenotype pathogen binding of chitin with host present PHIPO:0001243 A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is absent. alaynecuzick 2021-03-23T11:18:11Z pathogen_host_interaction_phenotype pathogen binding of chitin with host absent PHIPO:0001244 A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is greater than normal. alaynecuzick 2021-04-13T12:41:33Z pathogen_host_interaction_phenotype increased number of pycnidia within host increased number of pathogen asexual sporulation structures within host lesion PHIPO:0001245 A host immune system signaling pathway pathogen-host interaction phenotype observed during the activation of host PAMP-triggered immunity in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. alaynecuzick 2021-04-21T11:49:31Z pathogen_host_interaction_phenotype increased protein phosphorylation involved in host PAMP-triggered immunity (MAPK) signaling activated by pathogen PHIPO:0001246 A phenotype where the process of pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), activate the host PAMP-triggered immunity (PTI) innate immune system to trigger host defense responses such as reactive oxygen species (ROS) and callose deposition is present. (PAMPs and MAMPs are conserved structures among microbial species, eg chitin and lipopolysaccharide (LPS)). alaynecuzick 2021-04-21T11:59:25Z host MAMP-triggered immunity activated by pathogen present host PTI activated by pathogen present pathogen_host_interaction_phenotype host PAMP-triggered immunity activated by pathogen present PHIPO:0001247 A pathogen host interaction phenotype, in which a pathogen effects a change in the metabolic processes of its host organism. alaynecuzick 2021-04-28T11:22:11Z pathogen_host_interaction_phenotype pathogen modulation of host metabolic process phenotype PHIPO:0001248 A pathogen host interaction phenotype, in which a pathogen effector preventing the hydrolysis of chitin by host chitinases is present. alaynecuzick 2021-04-28T11:28:06Z pathogen_host_interaction_phenotype PAMP receptor decoy activity present pathogen modulation of chitin hydrolysis by host present PHIPO:0001249 A single species metabolic cellular process phenotype, in which a pathogen effector prevents the hydrolysis of chitin by chitinases. alaynecuzick 2021-04-30T10:10:15Z single_species_phenotype PAMP receptor decoy activity present chitin hydrolysis absent PHIPO:0001250 A pathogen host interaction phenotype where the development of a host structure is abnormal during pathogen infection. alaynecuzick 2021-08-16T12:59:12Z pathogen_host_interaction_phenotype abnormal host structure induced by pathogen PHIPO:0001251 A pathogen host interaction phenotype, in which the host protein usually present during infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2022-06-15T11:06:24Z host protein involved in a pathogen interaction present pathogen_host_interaction_phenotype host defense-induced protein present PHIPO:0001252 A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is decreased. alaynecuzick 2022-06-15T11:13:29Z pathogen_host_interaction_phenotype decreased pathogen tissue to tissue migration within host PHIPO:0001253 A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection is present. (GO:0006954 inflammatory response). alaynecuzick 2022-06-17T11:09:50Z inflammation present pathogen_host_interaction_phenotype host immune system inflammatory response activated by pathogen present PHIPO:0001254 A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a lesser extent than normal. (GO:0006954 inflammatory response). alaynecuzick 2022-06-17T11:49:45Z decreased inflammation pathogen_host_interaction_phenotype decreased host immune inflammatory response with pathogen PHIPO:0001255 A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a greater extent than normal. (GO:0006954 inflammatory response). alaynecuzick 2022-06-20T09:58:39Z increased inflammation pathogen_host_interaction_phenotype increased host immune inflammatory response with pathogen PHIPO:0001256 A pathogen host interaction phenotype, in which the host defense-related protein usually present during infection is normal (i.e. indistinguishable from wild type). alaynecuzick 2022-06-20T10:03:29Z pathogen_host_interaction_phenotype host defense-related protein involved in a pathogen interaction present PHIPO:0001257 A pathogen host interaction phenotype, in which the level of host protein usually present during infection is lower than normal. alaynecuzick 2022-06-20T10:21:16Z pathogen_host_interaction_phenotype decreased level of host defense-induced protein PHIPO:0001258 A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is lower than normal. alaynecuzick 2022-06-20T10:23:47Z pathogen_host_interaction_phenotype decreased expression of a host defense-related protein involved in a pathogen interaction PHIPO:0001259 A pathogen host interaction cell level phenotype which affects the viability of a host cell in the presence of a pathogen. alaynecuzick 2022-07-01T09:19:41Z cytotoxicity phenotype pathogen_host_interaction_phenotype host cell viability with pathogen phenotype PHIPO:0001260 A host cell viability phenotype where the host cell survives in the presence of the pathogen. alaynecuzick 2022-07-01T09:24:19Z pathogen_host_interaction_phenotype host cell viable with pathogen PHIPO:0001261 A host cell viability phenotype where the host cell death is accelerated by the pathogen. alaynecuzick 2022-07-01T09:27:27Z pathogen_host_interaction_phenotype host cell inviable with pathogen PHIPO:0001262 A pathogen host interaction phenotype, which affects the level of a host produced protein during infection. alaynecuzick 2022-07-01T09:51:01Z pathogen_host_interaction_phenotype host defense-induced protein level phenotype PHIPO:0001263 A pathogen host interaction phenotype, which affects the level of a host produced RNA during infection. alaynecuzick 2022-07-01T09:59:49Z pathogen_host_interaction_phenotype host defense-induced RNA level phenotype PHIPO:0001264 A pathogen host interaction phenotype, in which a pathogen effects a change in the physiological processes of its host organism. alaynecuzick 2022-07-04T08:38:22Z pathogen_host_interaction_phenotype host physiological process affected by pathogen phenotype PHIPO:0001265 A pathogen host interaction phenotype in which host bleeding occurs during pathogen infection (MP:0001914 hemorrhage). alaynecuzick 2022-07-04T08:41:51Z host bleeding with pathogen present host haemorrhage with pathogen present pathogen_host_interaction_phenotype host hemorrhage with pathogen present PHIPO:0001266 A pathogen host interaction phenotype in which the host bleeding during pathogen infection occurs to a greater extent than normal (MP:0001914 hemorrhage). alaynecuzick 2022-07-04T08:45:10Z increased host bleeding with pathogen increased host haemorrhage with pathogen pathogen_host_interaction_phenotype increased host hemorrhage with pathogen PHIPO:0001267 A pathogen host interaction phenotype, which affects the level of pathogen produced RNA during host infection. alaynecuzick 2022-07-04T08:58:03Z pathogen_host_interaction_phenotype level of pathogen produced RNA within host phenotype PHIPO:0001268 A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in the abnormal growth of the host tissue, forming a plant gall (BTO:0005833 plant gall). alaynecuzick 2022-07-05T12:52:20Z pathogen_host_interaction_phenotype presence of host gall during pathogen invasion PHIPO:0001269 A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased number of plant galls (BTO:0005833 plant gall). alaynecuzick 2022-07-05T12:57:02Z pathogen_host_interaction_phenotype decreased number of host galls during pathogen invasion PHIPO:0001270 A growth phenotype which describes the sensitivity of individuals or populations after exposure to calcium ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2022-07-27T11:20:23Z FYPO:0001201 hypersensitive to calcium ion starvation reduced growth in low calcium sensitive to calcium ion depletion sensitive to calcium ion deprivation sensitive to calcium starvation single_species_phenotype sensitive to calcium ion starvation PHIPO:0001271 A pathogen reproductive phenotype within host in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type). alaynecuzick 2022-08-15T16:22:41Z presence of pathogen teliospores within host pathogen_host_interaction_phenotype presence of pathogen sexual spores within host PHIPO:0001272 A single species growth phenotype where there is a decrease in size of an entire multicellular organism. alaynecuzick 2022-08-25T08:11:36Z single_species_phenotype stunted growth PHIPO:0001273 A pathogen host interaction phenotype where the morphology of the host cell is irregular due to the phagocytosis (engulfment and ingestion) of the pathogen (GO:0006911). alaynecuzick 2022-08-25T09:26:08Z irregular host morphology during phagocytosis of pathogen pathogen_host_interaction_phenotype abnormal host morphology during phagocytosis of pathogen PHIPO:0001274 A pathogen host interaction phenotype where the host immune system activates the phagocytosis of a pathogen (GO:0006911). alaynecuzick 2022-08-25T10:07:49Z pathogen_host_interaction_phenotype host immune system phagocytosis of pathogen present PHIPO:0001275 A pathogen reproductive phenotype within host in which the viability of sexual spores is normal (i.e. indistinguishable from wild type). alaynecuzick 2022-09-09T13:22:21Z pathogen_host_interaction_phenotype presence of viable pathogen sexual spores within host PHIPO:0001276 A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of plant galls (BTO:0005833 plant gall). alaynecuzick 2022-09-09T13:28:14Z pathogen_host_interaction_phenotype increased number of host galls during pathogen invasion PHIPO:0001277 A pathogen host interaction phenotype in which host DNA synthesis occurs during pathogen infection (GO:0090592 DNA synthesis involved in DNA replication). alaynecuzick 2022-09-09T14:04:31Z pathogen_host_interaction_phenotype presence of pathogen induced host DNA synthesis PHIPO:0001278 A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a lesser extent than normal (GO:0090592 DNA synthesis involved in DNA replication). alaynecuzick 2022-09-09T14:06:29Z pathogen_host_interaction_phenotype decreased pathogen induced host DNA synthesis PHIPO:0001279 A single species molecular function phenotype in which a peptidase activity is absent. alaynecuzick 2022-11-07T10:37:31Z FYPO:0000669 abolished protease activity peptidase activity abolished single_species_phenotype abolished peptidase activity PHIPO:0001280 A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a greater extent than normal (GO:0090592 DNA synthesis involved in DNA replication). alaynecuzick 2022-11-07T14:30:40Z pathogen_host_interaction_phenotype increased pathogen induced host DNA synthesis PHIPO:0001281 A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, occurs during pathogen infection (GO:0006468 protein phosphorylation). alaynecuzick 2022-11-11T13:05:20Z pathogen_host_interaction_phenotype presence of host protein phosphorylation with pathogen PHIPO:0001282 A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, does not occur during pathogen infection (GO:0006468 protein phosphorylation). alaynecuzick 2022-11-11T13:06:37Z pathogen_host_interaction_phenotype absence of host protein phosphorylation with pathogen PHIPO:0001283 A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a greater extent than normal (GO:0006468 protein phosphorylation). alaynecuzick 2022-11-11T13:10:07Z pathogen_host_interaction_phenotype increased host protein phosphorylation with pathogen PHIPO:0001284 A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a lesser extent than normal (GO:0006468 protein phosphorylation). alaynecuzick 2022-11-11T13:11:15Z pathogen_host_interaction_phenotype decreased host protein phosphorylation with pathogen PHIPO:0001285 A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is higher than normal. alaynecuzick 2022-11-22T10:38:36Z increased level of host defense related RNA involved in a pathogen interaction pathogen_host_interaction_phenotype increased level of host defense-related RNA involved in a pathogen interaction PHIPO:0001286 A molecular function phenotype in which the binding of one pathogen protein to host DNA is present. alaynecuzick 2022-11-22T10:43:32Z presence of pathogen protein host DNA binding pathogen_host_interaction_phenotype presence of pathogen protein host DNA interaction PHIPO:0001287 A growth phenotype which describes the absence of change of individuals or populations after exposure to tolnaftate (i.e. indistinguishable from wild type). alaynecuzick 2023-06-12T08:49:10Z single_species_phenotype normal growth on tolnaftate PHIPO:0001288 A growth phenotype which describes the resistance of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-06-12T09:02:28Z single_species_phenotype resistance to tolnaftate PHIPO:0001289 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-06-12T09:05:32Z single_species_phenotype sensitive to tolnaftate PHIPO:0001290 A growth phenotype which describes the absence of change of individuals or populations after exposure to azoxystrobin (i.e. indistinguishable from wild type). alaynecuzick 2023-06-12T09:21:50Z single_species_phenotype normal growth on azoxystrobin PHIPO:0001291 A growth phenotype which describes the resistance of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-06-12T09:34:07Z single_species_phenotype resistance to fenpicoxamid PHIPO:0001292 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-06-12T09:37:49Z single_species_phenotype sensitive to fenpicoxamid PHIPO:0001293 A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpicoxamid (i.e. indistinguishable from wild type). alaynecuzick 2023-06-12T09:41:30Z single_species_phenotype normal growth on fenpicoxamid PHIPO:0001294 A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase is present. alaynecuzick 2023-06-16T11:19:19Z pathogen_host_interaction_phenotype inhibition of pathogen polygalacturonase by host present PHIPO:0001295 A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase occurs to a lesser extent than normal. alaynecuzick 2023-06-16T11:21:35Z pathogen_host_interaction_phenotype inhibition of pathogen polygalacturonase by host decreased PHIPO:0001296 A growth phenotype which describes the resistance of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-06-21T11:31:01Z single_species_phenotype resistance to arborcandin C PHIPO:0001297 A growth phenotype which describes the sensitivity of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-06-21T11:33:40Z single_species_phenotype sensitive to arborcandin C PHIPO:0001298 A growth phenotype which describes the absence of change of individuals or populations after exposure to arborcandin C (i.e. indistinguishable from wild type). alaynecuzick 2023-06-21T11:35:28Z single_species_phenotype normal growth on arborcandin C PHIPO:0001299 A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrrolnitrin (i.e. indistinguishable from wild type). alaynecuzick 2023-06-27T13:33:13Z single_species_phenotype normal growth on pyrrolnitrin PHIPO:0001300 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-06-27T13:35:46Z single_species_phenotype sensitive to pyrrolnitrin PHIPO:0001301 A growth phenotype which describes the resistance of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-06-27T13:37:29Z single_species_phenotype resistance to pyrrolnitrin PHIPO:0001302 A growth phenotype which describes the resistance of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2023-06-27T14:23:57Z FYPO:0000851 resistant to osmotic stress single_species_phenotype resistance to osmotic stress PHIPO:0001303 A growth phenotype which describes the sensitivity of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2023-06-27T14:27:20Z FYPO:0000270 single_species_phenotype sensitive to osmotic stress PHIPO:0001304 A growth phenotype which describes the resistance of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2023-06-30T12:46:55Z FYPO:0000852 ionic stress resistance: increased resistant to salt stress single_species_phenotype resistance to salt stress PHIPO:0001305 A growth phenotype which describes the resistance of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2023-06-30T12:55:08Z resistant to non-ionic osmotic stress single_species_phenotype resistance to non-ionic osmotic stress PHIPO:0001306 A growth phenotype which describes the sensitivity of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2023-06-30T12:57:45Z FYPO:0000271 hypersensitive to salt stress ionic stress resistance: decreased single_species_phenotype sensitive to salt stress PHIPO:0001307 A growth phenotype which describes the sensitivity of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. alaynecuzick 2023-06-30T13:00:44Z FYPO:0002811 hypersensitive to non-ionic osmotic stress single_species_phenotype sensitive to non-ionic osmotic stress PHIPO:0001308 A growth phenotype which describes the absence of change of individuals or populations after exposure to a specific chemical (i.e. indistinguishable from wild type). alaynecuzick 2023-07-21T15:06:54Z single_species_phenotype normal growth on chemical PHIPO:0001309 A growth phenotype which describes the absence of change of individuals or populations after exposure to benomyl (i.e. indistinguishable from wild type). alaynecuzick 2023-07-21T15:13:15Z single_species_phenotype normal growth on benomyl PHIPO:0001310 A growth phenotype which describes the absence of change of individuals or populations after exposure to carbendazim (i.e. indistinguishable from wild type). alaynecuzick 2023-07-21T15:16:51Z single_species_phenotype normal growth on carbendazim PHIPO:0001311 A growth phenotype which describes the absence of change of individuals or populations after exposure to chlorothalonil (i.e. indistinguishable from wild type). alaynecuzick 2023-08-02T16:52:35Z single_species_phenotype normal growth on chlorothalonil PHIPO:0001312 A growth phenotype which describes the absence of change of individuals or populations after exposure to zoxamide (i.e. indistinguishable from wild type). alaynecuzick 2023-08-02T16:56:31Z single_species_phenotype normal growth on zoxamide PHIPO:0001313 A growth phenotype which describes the resistance of individuals or populations after exposure to zoxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:00:21Z single_species_phenotype resistance to zoxamide PHIPO:0001314 A growth phenotype which describes the sensitivity of individuals or populations after exposure to zoxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:03:39Z single_species_phenotype sensitive to zoxamide PHIPO:0001315 A growth phenotype which describes the absence of change of individuals or populations after exposure to cymoxanil (i.e. indistinguishable from wild type). alaynecuzick 2023-08-02T17:08:04Z single_species_phenotype normal growth on cymoxanil PHIPO:0001316 A growth phenotype which describes the resistance of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:10:17Z single_species_phenotype resistance to cymoxanil PHIPO:0001317 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:12:34Z single_species_phenotype sensitive to cymoxanil PHIPO:0001318 A growth phenotype which describes the absence of change of individuals or populations after exposure to metalaxyl (i.e. indistinguishable from wild type). alaynecuzick 2023-08-02T17:43:33Z single_species_phenotype normal growth on metalaxyl PHIPO:0001319 A growth phenotype which describes the resistance of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:45:42Z single_species_phenotype resistance to metalaxyl PHIPO:0001320 A growth phenotype which describes the sensitivity of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:47:59Z single_species_phenotype sensitive to metalaxyl PHIPO:0001321 A growth phenotype which describes the absence of change of individuals or populations after exposure to flumorph (i.e. indistinguishable from wild type). alaynecuzick 2023-08-02T17:50:56Z single_species_phenotype normal growth on flumorph PHIPO:0001322 A growth phenotype which describes the resistance of individuals or populations after exposure to flumorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:53:00Z single_species_phenotype resistance to flumorph PHIPO:0001323 A growth phenotype which describes the sensitivity of individuals or populations after exposure to flumorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-02T17:55:02Z single_species_phenotype sensitive to flumorph PHIPO:0001324 A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimethanil (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:09:48Z single_species_phenotype normal growth on pyrimethanil PHIPO:0001325 A growth phenotype which describes the absence of change of individuals or populations after exposure to tebuconazole (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:15:40Z single_species_phenotype normal growth on tebuconazole PHIPO:0001326 A growth phenotype which describes the absence of change of individuals or populations after exposure to prochloraz (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:18:09Z single_species_phenotype normal growth on prochloraz PHIPO:0001327 A growth phenotype which describes the absence of change of individuals or populations after exposure to iprodione (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:20:20Z single_species_phenotype normal growth on iprodione PHIPO:0001328 A growth phenotype which describes the absence of change of individuals or populations after exposure to myclobutanil (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:22:50Z single_species_phenotype normal growth on myclobutanil PHIPO:0001329 A growth phenotype which describes the absence of change of individuals or populations after exposure to fluazinam (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:25:21Z single_species_phenotype normal growth on fluazinam PHIPO:0001330 A growth phenotype which describes the absence of change of individuals or populations after exposure to thiram (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:27:38Z single_species_phenotype normal growth on thiram PHIPO:0001331 A growth phenotype which describes the absence of change of individuals or populations after exposure to procymidone (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T12:29:52Z single_species_phenotype normal growth on procymidone PHIPO:0001332 A growth phenotype which describes the resistance of individuals or populations after exposure to procymidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:32:57Z single_species_phenotype resistance to procymidone PHIPO:0001333 A growth phenotype which describes the resistance of individuals or populations after exposure to thiram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:35:23Z single_species_phenotype resistance to thiram PHIPO:0001334 A growth phenotype which describes the resistance of individuals or populations after exposure to fluazinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:37:30Z single_species_phenotype resistance to fluazinam PHIPO:0001335 A growth phenotype which describes the resistance of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:39:12Z single_species_phenotype resistance to myclobutanil PHIPO:0001336 A growth phenotype which describes the sensitivity of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:45:23Z single_species_phenotype sensitive to myclobutanil PHIPO:0001337 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluazinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:47:42Z single_species_phenotype sensitive to fluazinam PHIPO:0001338 A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:50:06Z single_species_phenotype sensitive to thiram PHIPO:0001339 A growth phenotype which describes the sensitivity of individuals or populations after exposure to procymidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-05T12:52:11Z single_species_phenotype sensitive to procymidone PHIPO:0001340 A growth phenotype which describes the resistance of individuals or populations after exposure to nocodazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-05T14:36:00Z single_species_phenotype resistance to nocodazole PHIPO:0001341 A growth phenotype which describes the absence of change of individuals or populations after exposure to thiabendazole (i.e. indistinguishable from wild type). alaynecuzick 2023-08-05T14:38:27Z single_species_phenotype normal growth on thiabendazole A growth phenotype which describes the resistance of individuals or populations after exposure to triflumizole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001342 resistance to triflumizole PHIPO:0001342 A growth phenotype which describes the sensitivity of individuals or populations after exposure to triflumizole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001343 sensitive to triflumizole PHIPO:0001343 A growth phenotype which describes the absence of change of individuals or populations after exposure to triflumizole (i.e. indistinguishable from wild type). alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001344 normal growth on triflumizole PHIPO:0001344 A growth phenotype which describes the resistance of individuals or populations after exposure to bitertanol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001345 resistance to bitertanol PHIPO:0001345 A growth phenotype which describes the sensitivity of individuals or populations after exposure to bitertanol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001346 sensitive to bitertanol PHIPO:0001346 A growth phenotype which describes the absence of change of individuals or populations after exposure to bitertanol (i.e. indistinguishable from wild type). alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001347 normal growth on bitertanol PHIPO:0001347 A growth phenotype which describes the resistance of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001348 resistance to pyrifenox PHIPO:0001348 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001349 sensitive to pyrifenox PHIPO:0001349 A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrifenox (i.e. indistinguishable from wild type). alaynecuzick 2023-08-10T12:06:26Z single_species_phenotype PHIPO:0001350 normal growth on pyrifenox PHIPO:0001350 PHIPO:0001351 A growth phenotype which describes the absence of change of individuals or populations after exposure to itraconazole (i.e. indistinguishable from wild type). alaynecuzick 2023-09-06T13:58:46Z single_species_phenotype normal growth on itraconazole PHIPO:0001352 A growth phenotype which describes the absence of change of individuals or populations after exposure to amphotericin B (i.e. indistinguishable from wild type). alaynecuzick 2023-09-06T14:01:34Z single_species_phenotype normal growth on amphotericin B A growth phenotype which describes the resistance of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-09-11T11:50:04Z single_species_phenotype PHIPO:0001353 resistance to prothioconazole PHIPO:0001353 A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-09-11T11:50:04Z single_species_phenotype PHIPO:0001354 sensitive to prothioconazole PHIPO:0001354 A growth phenotype which describes the absence of change of individuals or populations after exposure to prothioconazole (i.e. indistinguishable from wild type). alaynecuzick 2023-09-11T11:50:04Z single_species_phenotype PHIPO:0001355 normal growth on prothioconazole PHIPO:0001355 A growth phenotype which describes the resistance of individuals or populations after exposure to fluopyram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-09-27T09:40:25Z single_species_phenotype PHIPO:0001356 resistance to fluopyram PHIPO:0001356 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluopyram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-09-27T09:40:25Z single_species_phenotype PHIPO:0001357 sensitive to fluopyram PHIPO:0001357 A growth phenotype which describes the absence of change of individuals or populations after exposure to fluopyram (i.e. indistinguishable from wild type). alaynecuzick 2023-09-27T09:40:25Z single_species_phenotype PHIPO:0001358 normal growth on fluopyram PHIPO:0001358 A growth phenotype which describes the resistance of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-09-28T11:07:02Z single_species_phenotype PHIPO:0001359 resistance to kresoxim-methyl PHIPO:0001359 A growth phenotype which describes the sensitivity of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-09-28T11:07:02Z single_species_phenotype PHIPO:0001360 sensitive to kresoxim-methyl PHIPO:0001360 A growth phenotype which describes the absence of change of individuals or populations after exposure to kresoxim-methyl (i.e. indistinguishable from wild type). alaynecuzick 2023-09-28T11:07:02Z single_species_phenotype PHIPO:0001361 normal growth on kresoxim-methyl PHIPO:0001361 A growth phenotype which describes the resistance of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001362 resistance to isopyrazam PHIPO:0001362 A growth phenotype which describes the sensitivity of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001363 sensitive to isopyrazam PHIPO:0001363 A growth phenotype which describes the absence of change of individuals or populations after exposure to isopyrazam (i.e. indistinguishable from wild type). alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001364 normal growth on isopyrazam PHIPO:0001364 A growth phenotype which describes the resistance of individuals or populations after exposure to bixafen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001365 resistance to bixafen PHIPO:0001365 A growth phenotype which describes the sensitivity of individuals or populations after exposure to bixafen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001366 sensitive to bixafen PHIPO:0001366 A growth phenotype which describes the absence of change of individuals or populations after exposure to bixafen (i.e. indistinguishable from wild type). alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001367 normal growth on bixafen PHIPO:0001367 A growth phenotype which describes the absence of change of individuals or populations after exposure to carboxin (i.e. indistinguishable from wild type). alaynecuzick 2023-10-02T14:15:15Z single_species_phenotype PHIPO:0001368 normal growth on carboxin PHIPO:0001368 PHIPO:0001369 An individual organism growth phenotype in which the rate, or speed, of hyphae formation is increased. alaynecuzick 2023-10-09T12:23:25Z fast hyphae formation single_species_phenotype increased rate of hyphae formation A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-10-10T15:36:59Z single_species_phenotype PHIPO:0001370 resistance to pyrimorph PHIPO:0001370 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-10-10T15:36:59Z single_species_phenotype PHIPO:0001371 sensitive to pyrimorph PHIPO:0001371 A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimorph (i.e. indistinguishable from wild type). alaynecuzick 2023-10-10T15:36:59Z single_species_phenotype PHIPO:0001372 normal growth on pyrimorph PHIPO:0001372 PHIPO:0001373 A phenotype that affects any anatomical structure physical quality, such as morphology, number, location, etc. alaynecuzick 2023-10-17T11:46:05Z single_species_phenotype anatomical structure physical quality phenotype PHIPO:0001374 A single species phenotype where the frequency of occurrence of resting structures is increased. alaynecuzick 2023-10-17T12:48:52Z single_species_phenotype increased number of sclerotia increased number of resting structures PHIPO:0001375 A single species phenotype where the frequency of occurrence of resting structures is decreased. alaynecuzick 2023-10-17T12:52:42Z single_species_phenotype decreased number of sclerotia decreased number of resting structures PHIPO:0001376 A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is normal in the vegetative growth phase of the life cycle (i.e. indistinguishable from wild type.) alaynecuzick 2023-10-17T13:00:17Z single_species_phenotype normal anatomical structure physical quality phenotype PHIPO:0001377 A single species phenotype where the number of resting structures is normal (i.e. indistinguishable from wild type). alaynecuzick 2023-10-17T13:03:53Z single_species_phenotype normal number of sclerotia normal number of resting structures A growth phenotype which describes the resistance of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-10-17T14:21:39Z single_species_phenotype PHIPO:0001378 resistance to tacrolimus PHIPO:0001378 A growth phenotype which describes the sensitivity of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-10-17T14:21:39Z single_species_phenotype PHIPO:0001379 sensitive to tacrolimus PHIPO:0001379 A growth phenotype which describes the absence of change of individuals or populations after exposure to tacrolimus (i.e. indistinguishable from wild type). alaynecuzick 2023-10-17T14:21:39Z single_species_phenotype PHIPO:0001380 normal growth on tacrolimus PHIPO:0001380 PHIPO:0001381 A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-11-13T15:10:47Z FYPO:0005825 hypersensitive to iron sensitive to iron ions single_species_phenotype sensitive to iron A growth phenotype which describes the resistance of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-11-21T10:43:41Z single_species_phenotype PHIPO:0001382 resistance to fenpiclonil PHIPO:0001382 A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-11-21T10:43:41Z single_species_phenotype PHIPO:0001383 sensitive to fenpiclonil PHIPO:0001383 A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpiclonil (i.e. indistinguishable from wild type). alaynecuzick 2023-11-21T10:43:41Z single_species_phenotype PHIPO:0001384 normal growth on fenpiclonil PHIPO:0001384 A growth phenotype which describes the resistance of individuals or populations after exposure to phenamacril. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-11-21T12:08:01Z single_species_phenotype PHIPO:0001385 resistance to phenamacril PHIPO:0001385 A growth phenotype which describes the sensitivity of individuals or populations after exposure to phenamacril. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-11-21T12:08:01Z single_species_phenotype PHIPO:0001386 sensitive to phenamacril PHIPO:0001386 A growth phenotype which describes the absence of change of individuals or populations after exposure to phenamacril (i.e. indistinguishable from wild type). alaynecuzick 2023-11-21T12:08:01Z single_species_phenotype PHIPO:0001387 normal growth on phenamacril PHIPO:0001387 A growth phenotype which describes the resistance of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2023-12-04T14:19:53Z resistance to SYP-Z048 single_species_phenotype PHIPO:0001388 resistance to pyrisoxazole PHIPO:0001388 A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2023-12-04T14:19:53Z sensitive to SYP-Z048 single_species_phenotype PHIPO:0001389 sensitive to pyrisoxazole PHIPO:0001389 A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrisoxazole (i.e. indistinguishable from wild type). alaynecuzick 2023-12-04T14:19:53Z normal growth on SYP-Z048 single_species_phenotype PHIPO:0001390 normal growth on pyrisoxazole PHIPO:0001390 A growth phenotype which describes the resistance of individuals or populations after exposure to metconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-10T15:25:16Z single_species_phenotype PHIPO:0001391 resistance to metconazole PHIPO:0001391 A growth phenotype which describes the sensitivity of individuals or populations after exposure to metconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-10T15:25:16Z single_species_phenotype PHIPO:0001392 sensitive to metconazole PHIPO:0001392 A growth phenotype which describes the absence of change of individuals or populations after exposure to metconazole (i.e. indistinguishable from wild type). alaynecuzick 2024-01-10T15:25:16Z single_species_phenotype PHIPO:0001393 normal growth on metconazole PHIPO:0001393 A growth phenotype which describes the resistance of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-22T12:34:13Z single_species_phenotype PHIPO:0001394 resistance to trifloxystrobin PHIPO:0001394 A growth phenotype which describes the sensitivity of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-22T12:34:13Z single_species_phenotype PHIPO:0001395 sensitive to trifloxystrobin PHIPO:0001395 A growth phenotype which describes the absence of change of individuals or populations after exposure to trifloxystrobin (i.e. indistinguishable from wild type). alaynecuzick 2024-01-22T12:34:13Z single_species_phenotype PHIPO:0001396 normal growth on trifloxystrobin PHIPO:0001396 PHIPO:0001397 A growth phenotype which describes the sensitivity of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2024-01-23T11:47:46Z single_species_phenotype sensitive to cell wall stress PHIPO:0001398 A growth phenotype which describes the sensitivity of individuals or populations after exposure to an oxidative stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). alaynecuzick 2024-01-23T12:01:41Z single_species_phenotype sensitive to oxidative stress A growth phenotype which describes the resistance of individuals or populations after exposure to flusilazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001399 resistance to flusilazole PHIPO:0001399 A growth phenotype which describes the sensitivity of individuals or populations after exposure to flusilazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001400 sensitive to flusilazole PHIPO:0001400 A growth phenotype which describes the absence of change of individuals or populations after exposure to flusilazole (i.e. indistinguishable from wild type). alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001401 normal growth on flusilazole PHIPO:0001401 A growth phenotype which describes the resistance of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001402 resistance to mandipropamid PHIPO:0001402 A growth phenotype which describes the sensitivity of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001403 sensitive to mandipropamid PHIPO:0001403 A growth phenotype which describes the absence of change of individuals or populations after exposure to mandipropamid (i.e. indistinguishable from wild type). alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001404 normal growth on mandipropamid PHIPO:0001404 A growth phenotype which describes the resistance of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001405 resistance to dimethomorph PHIPO:0001405 A growth phenotype which describes the sensitivity of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001406 sensitive to dimethomorph PHIPO:0001406 A growth phenotype which describes the absence of change of individuals or populations after exposure to dimethomorph (i.e. indistinguishable from wild type). alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001407 normal growth on dimethomorph PHIPO:0001407 A growth phenotype which describes the resistance of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001408 resistance to iprovalicarb PHIPO:0001408 A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001409 sensitive to iprovalicarb PHIPO:0001409 A growth phenotype which describes the absence of change of individuals or populations after exposure to iprovalicarb (i.e. indistinguishable from wild type). alaynecuzick 2024-01-30T14:16:53Z single_species_phenotype PHIPO:0001410 normal growth on iprovalicarb PHIPO:0001410 A growth phenotype which describes the resistance of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-02-05T09:44:00Z single_species_phenotype PHIPO:0001411 resistance to dalfopristin PHIPO:0001411 A growth phenotype which describes the sensitivity of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-02-05T09:44:00Z single_species_phenotype PHIPO:0001412 sensitive to dalfopristin PHIPO:0001412 A growth phenotype which describes the absence of change of individuals or populations after exposure to dalfopristin (i.e. indistinguishable from wild type). alaynecuzick 2024-02-05T09:44:00Z single_species_phenotype PHIPO:0001413 normal growth on dalfopristin PHIPO:0001413 A growth phenotype which describes the resistance of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001414 resistance to thifluzamide PHIPO:0001414 A growth phenotype which describes the sensitivity of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001415 sensitive to thifluzamide PHIPO:0001415 A growth phenotype which describes the absence of change of individuals or populations after exposure to thifluzamide (i.e. indistinguishable from wild type). alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001416 normal growth on thifluzamide PHIPO:0001416 A growth phenotype which describes the resistance of individuals or populations after exposure to penflufen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001417 resistance to penflufen PHIPO:0001417 A growth phenotype which describes the sensitivity of individuals or populations after exposure to penflufen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001418 sensitive to penflufen PHIPO:0001418 A growth phenotype which describes the absence of change of individuals or populations after exposure to penflufen (i.e. indistinguishable from wild type). alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001419 normal growth on penflufen PHIPO:0001419 A growth phenotype which describes the resistance of individuals or populations after exposure to flutolanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001420 resistance to flutolanil PHIPO:0001420 A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutolanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001421 sensitive to flutolanil PHIPO:0001421 A growth phenotype which describes the absence of change of individuals or populations after exposure to flutolanil (i.e. indistinguishable from wild type). alaynecuzick 2024-02-07T11:32:37Z single_species_phenotype PHIPO:0001422 normal growth on flutolanil PHIPO:0001422 A growth phenotype which describes the resistance of individuals or populations after exposure to imazalil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-02-12T10:06:39Z single_species_phenotype PHIPO:0001423 resistance to imazalil PHIPO:0001423 A growth phenotype which describes the sensitivity of individuals or populations after exposure to imazalil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-02-12T10:06:39Z single_species_phenotype PHIPO:0001424 sensitive to imazalil PHIPO:0001424 A growth phenotype which describes the absence of change of individuals or populations after exposure to imazalil (i.e. indistinguishable from wild type). alaynecuzick 2024-02-12T10:06:39Z single_species_phenotype PHIPO:0001425 normal growth on imazalil PHIPO:0001425 PHIPO:0001426 A growth phenotype which describes the absence of change of individuals or populations after exposure to fludioxonil (i.e. indistinguishable from wild type). alaynecuzick 2024-02-28T09:44:54Z single_species_phenotype normal growth on fludioxonil PHIPO:0001427 A single species cell morphology phenotype in which fungal hyphae branching is abnormal. alaynecuzick 2024-03-04T15:00:58Z single_species_phenotype abnormal hyphal branching PHIPO:0001428 A growth phenotype which describes the absence of change of individuals or populations after exposure to brefeldin A (i.e. indistinguishable from wild type). alaynecuzick 2024-03-12T15:12:17Z single_species_phenotype normal growth on brefeldin A PHIPO:0001429 A growth phenotype which describes the absence of change of individuals or populations after exposure to fluconazole (i.e. indistinguishable from wild type). alaynecuzick 2024-03-12T15:14:22Z single_species_phenotype normal growth on fluconazole A growth phenotype which describes the resistance of individuals or populations after exposure to ipconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001430 resistance to ipconazole PHIPO:0001430 A growth phenotype which describes the sensitivity of individuals or populations after exposure to ipconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001431 sensitive to ipconazole PHIPO:0001431 A growth phenotype which describes the absence of change of individuals or populations after exposure to ipconazole (i.e. indistinguishable from wild type). alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001432 normal growth on ipconazole PHIPO:0001432 A growth phenotype which describes the resistance of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001433 resistance to cyprodinil PHIPO:0001433 A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001434 sensitive to cyprodinil PHIPO:0001434 A growth phenotype which describes the absence of change of individuals or populations after exposure to cyprodinil (i.e. indistinguishable from wild type). alaynecuzick 2024-03-18T13:26:33Z single_species_phenotype PHIPO:0001435 normal growth on cyprodinil PHIPO:0001435 A growth phenotype which describes the absence of change of individuals or populations after exposure to caspofungin (i.e. indistinguishable from wild type). alaynecuzick 2024-03-27T11:45:23Z single_species_phenotype PHIPO:0001436 normal growth on caspofungin PHIPO:0001436 A growth phenotype which describes the absence of change of individuals or populations after exposure to terbinafine (i.e. indistinguishable from wild type). alaynecuzick 2024-03-27T11:45:23Z single_species_phenotype PHIPO:0001437 normal growth on terbinafine PHIPO:0001437 A growth phenotype which describes the absence of change of individuals or populations after exposure to bifonazole (i.e. indistinguishable from wild type). alaynecuzick 2024-03-27T11:45:23Z single_species_phenotype PHIPO:0001438 normal growth on bifonazole PHIPO:0001438 PHIPO:0001439 A single species phenotype where the frequency of occurrence of septum within an asexual spore is increased. alaynecuzick 2024-08-03T10:37:57Z single_species_phenotype increased number of septum in asexual spore PHIPO:0001440 A single species phenotype where the frequency of occurrence of nuclei within an asexual spore is increased. alaynecuzick 2024-08-03T10:45:41Z single_species_phenotype increased number of nuclei in asexual spore An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. natural protein native protein protein PR:000000001 The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. protein PR:000000001 An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. PRO:DAN PRO:WCB natural protein PRO:DAN native protein IEDB:BP 2 An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. peptide polypeptide protein PR:000018263 Category=polymer. amino acid chain PR:000018263 An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. PRO:DAN PRO:JSG peptide PRO:DAN polypeptide PRO:DAN A protein that is encoded in the genome of some Eukaryota. Eukaryota protein protein PR:000036194 eukaryotic protein PR:000036194 A protein that is encoded in the genome of some Eukaryota. PRO:DAN Eukaryota protein PRO:DAN A material entity that minimally consists of a protein. protein protein aggregate protein complex protein-containing complex protein PR:000050567 Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566). protein-containing material entity PR:000050567 A material entity that minimally consists of a protein. PRO:DAN protein PRO:DAN protein aggregate PRO:DAN protein complex PRO:DAN protein-containing complex PRO:DAN SO:0000704 An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. BFO:0000003 uberon UBERON:0000000 processual entity UBERON:0000000 An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. span:ProcessualEntity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. AAO:0010825 AEO:0000003 BILA:0000003 CARO:0000003 EHDAA2:0003003 EMAPA:0 FBbt:00007001 FMA:305751 FMA:67135 GAID:781 HAO:0000003 MA:0003000 MESH:D000825 SCTID:362889002 TAO:0000037 TGMA:0001823 VHOG:0001759 XAO:0003000 ZFA:0000037 http://dbpedia.org/ontology/AnatomicalStructure biological structure connected biological structure uberon UBERON:0000061 anatomical structure UBERON:0000061 Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 FBbt:00007001 connected biological structure CARO:0000003 The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. adult stage BTO:0001043 BilaDO:0000004 EFO:0001272 FBdv:00005369 WBls:0000041 XtroDO:0000084 fully formed animal stage juvenile-adult stage uberon UBERON:0000066 fully formed stage https://github.com/obophenotype/uberon/issues/566 UBERON:0000066 The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. https://orcid.org/0000-0002-6601-2165 A life cycle stage that starts with fertilization and ends with the fully formed embryo. BilaDO:0000002 EV:0300001 FBdv:00005289 FMA:72652 HsapDv:0000002 MmusDv:0000002 OGES:000000 OGES:000022 SCTID:296280003 WBls:0000003 WBls:0000092 WBls:0000102 XAO:1000012 embryonic stage uberon embryogenesis UBERON:0000068 embryo stage UBERON:0000068 A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://orcid.org/0000-0002-6601-2165 End of the life of an organism. ncit:Death is an outcome XAO:0000437 XtroDO:0000085 uberon death UBERON:0000071 death stage UBERON:0000071 End of the life of an organism. XAO:0000437 ncit:Death is an outcome ncit Stage succeeding embryo, including mature structure. In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997) BilaDO:0000003 OGES:000010 OGES:000014 OGES:000024 WBls:0000022 WBls:0000093 WBls:0000103 postembryonic stage post-hatching stage uberon postembryonic UBERON:0000092 post-embryonic stage https://github.com/obophenotype/uberon/issues/344 UBERON:0000092 Stage succeeding embryo, including mature structure. https://orcid.org/0000-0002-6601-2165 An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism. FBdv:00000000 HsapDv:0000001 MmusDv:0000001 OGES:000011 ncithesaurus:Life entire life cycle entire lifespan life lifespan uberon UBERON:0000104 life cycle https://github.com/obophenotype/uberon/issues/532 UBERON:0000104 An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism. https://orcid.org/0000-0002-6601-2165 A spatiotemporal region encompassing some part of the life cycle of an organism. this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here the WBls class 'all stages' belongs here as it is the superclass of other WBls stages we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage BILS:0000105 EFO:0000399 FBdv:00007012 FMA:24120 HsapDv:0000000 MESH:D008018 MmusDv:0000000 OlatDv:0000010 PdumDv:0000090 WBls:0000002 XAO:1000000 ZFS:0000000 ZFS:0100000 ncithesaurus:Developmental_Stage developmental stage stage uberon UBERON:0000105 life cycle stage UBERON:0000105 A spatiotemporal region encompassing some part of the life cycle of an organism. https://orcid.org/0000-0002-6601-2165 A stage at which the organism is a single cell produced by means of sexual reproduction. As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG] BILS:0000106 BilaDO:0000005 EFO:0001322 EHDAA:27 FBdv:00005288 IDOMAL:0000302 NCIT:C12601 PdumDv:0000100 VHOG:0000745 Wikipedia:Zygote XAO:1000001 ZFS:0000001 1-cell stage fertilized egg stage one cell stage uberon fertilized egg stage one-cell stage zygote zygotum UBERON:0000106 zygote stage UBERON:0000106 A stage at which the organism is a single cell produced by means of sexual reproduction. Wikipedia:Zygote As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG] 2012-09-17 VHOG:0000745 VHOG ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107 http://bgee.unil.ch/ IDOMAL:0000302 https://github.com/biopragmatics/biomappings fertilized egg stage BTO:0000854 one-cell stage VHOG:0000745 zygote VHOG:0000745 zygotum Wikipedia:Zygote A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. BILS:0000111 BilaDO:0000010 HsapDv:0000015 MmusDv:0000018 OGES:000005 OGES:000032 Wikipedia:Organogenesis uberon segmentation stage UBERON:0000111 organogenesis stage https://github.com/obophenotype/developmental-stage-ontologies/issues/84 https://github.com/obophenotype/uberon/issues/533 UBERON:0000111 A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. Wikipedia:Organogenesis Anatomical entity that has mass. AAO:0010264 AEO:0000006 BILA:0000006 CARO:0000006 EHDAA2:0003006 FBbt:00007016 FMA:67165 HAO:0000006 TAO:0001836 TGMA:0001826 VHOG:0001721 uberon UBERON:0000465 material anatomical entity UBERON:0000465 Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 FBbt:00007016 Anatomical structure that is an individual member of a species and consists of more than one cell. TODO - split body and mc organism? body continues after death stage organismal organism AAO:0010026 AEO:0000191 BILA:0000012 BIRNLEX:18 BSA:0000038 BTO:0000042 CARO:0000012 EFO:0002906 EHDAA2:0003103 EHDAA2:0003191 EHDAA:1 EMAPA:25765 EV:0100016 FBbt:00000001 FMA:256135 HAO:0000012 NCIT:C13041 SCTID:243928005 TADS:0000001 TAO:0001094 TGMA:0001832 VHOG:0000671 WBbt:0007833 Wikipedia:Multi-cellular_organism XAO:0003004 ZFA:0001094 galen:Organism ncithesaurus:Whole_Organism multi-cellular organism uberon Koerper body whole body whole organism UBERON:0000468 multicellular organism UBERON:0000468 Anatomical structure that is an individual member of a species and consists of more than one cell. CARO:0000012 Wikipedia:Multi-cellular_organism http://orcid.org/0000-0001-9114-8737 organism FBbt:00000001 VHOG:0000671 WBbt:0007833 FBbt:00000001 multi-cellular organism CARO:0000012 Koerper BTO:0001489 body AEO:0000103 BIRNLEX:18 FMA:256135 NCIT:C13041 whole body BTO:0001489 whole organism FBbt:00000001 Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. embryonic Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo AAO:0011035 AEO:0000169 BILA:0000056 BSA:0000039 BTO:0000379 CALOHA:TS-0229 EFO:0001367 EHDAA2:0000002 EHDAA2_RETIRED:0003236 EHDAA:38 EMAPA:16039 FBbt:00000052 FMA:69068 GAID:963 IDOMAL:0000646 MAT:0000226 MESH:D004622 MIAA:0000019 NCIT:C28147 OGEM:000001 SCTID:57991002 UMLS:C0013935 VHOG:0001766 Wikipedia:Embryo XAO:0000113 ZFA:0000103 http://neurolex.org/wiki/Category:Embryonic_organism embryonic organism uberon developing organism developmental tissue UBERON:0000922 embryo https://github.com/obophenotype/uberon/issues/503 UBERON:0000922 https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. BTO:0000379 FB:FBrf0039741 FB:FBrf0041814 GO:0009790 Wikipedia:Embryo Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA FBbt:00000052 IDOMAL:0000646 https://github.com/biopragmatics/biomappings UMLS:C0013935 ncithesaurus:Embryo embryonic organism BILA:0000056 developing organism BILA:0000056 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. AAO:0010841 AEO:0000000 BFO:0000004 BILA:0000000 BIRNLEX:6 CARO:0000000 EHDAA2:0002229 FBbt:10000000 FMA:62955 HAO:0000000 MA:0000001 NCIT:C12219 TAO:0100000 TGMA:0001822 UMLS:C1515976 WBbt:0000100 XAO:0000000 ZFA:0100000 uberon UBERON:0001062 anatomical entity UBERON:0001062 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. FMA:62955 http://orcid.org/0000-0001-9114-8737 FBbt:10000000 UMLS:C1515976 ncithesaurus:Anatomic_Structure_System_or_Substance A multicellular organism that existence_starts_with a post-embryonic stage. MA:0002405 postnatal organism TS28 mouse post-hatching organism post-natal organism postnatal mouse uberon UBERON:0009953 post-embryonic organism https://github.com/obophenotype/uberon/issues/667 UBERON:0009953 A multicellular organism that existence_starts_with a post-embryonic stage. OBOL:automatic TS28 mouse MA:0002405 post-hatching organism https://orcid.org/0000-0002-6601-2165 post-natal organism https://orcid.org/0000-0002-6601-2165 postnatal mouse MA:0002405 An anatomical structure that has more than one cell as a part. CARO:0010000 FBbt:00100313 multicellular structure uberon UBERON:0010000 multicellular anatomical structure UBERON:0010000 An anatomical structure that has more than one cell as a part. CARO:0010000 FBbt:00100313 multicellular structure FBbt:00100313 oboInOwl:Subset owl:Nothing example to be eventually removed example to be eventually removed The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job Person:Alan Ruttenberg failed exploratory term metadata complete Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. metadata complete organizational term Term created to ease viewing/sort terms for development purpose, and will not be included in a release term created to ease viewing/sort terms for development purpose, and will not be included in a release organizational term ready for release Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." ready for release metadata incomplete Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. metadata incomplete uncurated Nothing done yet beyond assigning a unique class ID and proposing a preferred term. uncurated pending final vetting All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. pending final vetting Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes. PERSON: Alan Ruttenberg PERSON: Melanie Courtot core placeholder removed An editor note should explain what were the merged terms and the reason for the merge. terms merged This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use. term imported This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created. term split Hard to give a definition for. Intuitively a "natural kind" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents. Alan Ruttenberg A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf universal A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal "definitions", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal. Alan Ruttenberg defined class A named class expression is a logical expression that is given a name. The name can be used in place of the expression. named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions Alan Ruttenberg named class expression to be replaced with external ontology term Terms with this status should eventually replaced with a term from another ontology. Alan Ruttenberg group:OBI to be replaced with external ontology term requires discussion A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. Alan Ruttenberg group:OBI requires discussion 2024-08-29 has part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) a core relation that holds between a whole and its part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/ Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. has_part BFO:0000051 external quality has_part has_part has part has part has_part preceded by x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. is preceded by preceded_by http://www.obofoundry.org/ro/#OBO_REL:preceded_by BFO:0000062 external preceded_by preceded_by preceded by preceded by precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. BFO:0000063 external precedes precedes precedes precedes occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t occurs_in unfolds in unfolds_in BFO:0000066 external occurs_in occurs_in Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant occurs in occurs in https://wiki.geneontology.org/Occurs_in GOREL:0002004 external results_in_fission_of results_in_fission_of results in fission of results_in_fission_of bearer of this apple is bearer of this red color this vase is bearer of this fragility Inverse of characteristic_of a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. bearer_of is bearer of RO:0000053 external bearer_of bearer_of bearer of bearer of has characteristic this apple has quality this red color a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist. has_quality has quality this person has role this investigator role (more colloquially: this person has this role of investigator) a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. has_role has role a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence has disposition x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. David Osumi-Sutherland t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) simultaneous with RO:0002092 external happens_during happens_during happens during RO:0002093 external ends_during ends_during ends during lactation SubClassOf 'only in taxon' some 'Mammalia' x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g. 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria only in taxon p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. GO Regulation precludes parthood; the regulatory process may not be within the regulated process. regulates (processual) false RO:0002211 external regulates regulates regulates regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. negatively regulates (process to process) RO:0002212 external negatively_regulates negatively_regulates negatively regulates negatively regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. positively regulates (process to process) RO:0002213 external positively_regulates positively_regulates positively regulates positively regulates mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974) osteoclast SubClassOf 'capable of' some 'bone resorption' A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. has function realized in For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)". RO:0002215 external capable_of capable_of capable of capable of inverse of starts with Chris Mungall Allen starts Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall started by RO:0002224 external starts_with starts_with starts with starts with inverse of ends with Chris Mungall ends x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall finished by RO:0002230 external ends_with ends_with ends with ends with p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint. RO:0002295 external results_in_developmental_progression_of results_in_developmental_progression_of results in developmental progression of results in developmental progression of every flower development (GO:0009908) results in development of some flower (PO:0009046) p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://www.geneontology.org/GO.doc.development.shtml RO:0002296 external results_in_development_of results_in_development_of results in development of results in development of an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists. every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062) Chris Mungall GOC:mtg_berkeley_2013 RO:0002297 external results_in_formation_of results_in_formation_of results in formation of results in formation of results in formation of anatomical entity an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast. The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity GOC:mtg_berkeley_2013 RO:0002315 external results_in_acquisition_of_features_of results_in_acquisition_of_features_of results in acquisition of features of results in acquisition of features of This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. RO:0002338 external has_target_start_location has_target_start_location has target start location has target start location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. RO:0002339 external has_target_end_location has_target_end_location has target end location has target end location 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739) RO:0002344 external results_in_transport_to_from_or_in results_in_transport_to_from_or_in results in transport to from or in results in transport to from or in x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). existence starts with x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends with x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. existence ends during or before RO:0002588 external results_in_assembly_of results_in_assembly_of results in assembly of RO:0002590 external results_in_disassembly_of results_in_disassembly_of results in disassembly of p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c RO:0002592 external results_in_organization_of results_in_organization_of results in organization of p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. 2018-12-13T11:26:17Z RO:0004007 external has_primary_input_or_output has_primary_input_or_output has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. 2018-12-13T11:26:32Z RO:0004008 external has_primary_output has_primary_output has primary output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. GOC:dph GOC:kva GOC:pt PMID:27812932 p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. 2018-12-13T11:26:56Z RO:0004009 external has_primary_input has_primary_input has primary input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. GOC:dph GOC:kva GOC:pt PMID:27812932 q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. increased in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. This relation is used to determine the 'directionality' of relative qualities such as 'decreased strength', relative to the parent type, 'strength'. decreased in magnitude relative to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. https://orcid.org/0000-0002-6601-2165 has relative magnitude q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. There are frequently two ways to state the same thing: we can say 'spermatocyte lacks asters' or 'asters absent from spermatocyte'. In this case the quality is 'lacking all parts of type' - it is a (relational) quality of the spermatocyte, and it is with respect to instances of 'aster'. One of the popular requirements of PATO is that it continue to support 'absent', so we need to relate statements which use this quality to the 'lacking all parts of type' quality. reciprocal of q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. https://orcid.org/0000-0002-6601-2165 alaynecuzick 2018-07-09T13:43:00Z Ontology of species-neutral phenotypes observed in pathogen-host interactions. Pathogen Host Interactions Phenotype Ontology https://creativecommons.org/licenses/by/3.0/ 2024-08-29 2 1 2 true MF(X)-directly_regulates->MF(Y)-enabled_by->GP(Z) => MF(Y)-has_input->GP(Y) e.g. if 'protein kinase activity'(X) directly_regulates 'protein binding activity (Y)and this is enabled by GP(Z) then X has_input Z infer input from direct reg GP(X)-enables->MF(Y)-has_part->MF(Z) => GP(X) enables MF(Z), e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase coupled transporter activity' has_part 'ATPase activity' then GP(X) enables 'ATPase activity' enabling an MF enables its parts true GP(X)-enables->MF(Y)-part_of->BP(Z) => GP(X) involved_in BP(Z) e.g. if X enables 'protein kinase activity' and Y 'part of' 'signal tranduction' then X involved in 'signal transduction' involved in BP If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this. inferring direct reg edge from input to regulatory subfunction inferring direct neg reg edge from input to regulatory subfunction inferring direct positive reg edge from input to regulatory subfunction effector input is compound function input Input of effector is input of its parent MF if effector directly regulates X, its parent MF directly regulates X if effector directly positively regulates X, its parent MF directly positively regulates X if effector directly negatively regulates X, its parent MF directly negatively regulates X 'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties). 'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).