Sylvain Croteau Yasmine Lisa Rebaine Alan Ruttenberg Albert Goldfain Anand Kumar Barry Smith Bill Hogan Brian Aevermann Cornelius Rosse Daniel Merico Jie Zheng Lindsay Cowell Michal Iglewski Richard Scheuermann Sabrina Azzi Sivaram Arabandi Werner Ceusters 2009-08-07 2024-07-10 Pneumonia Diagnosis Ontology (PNADO) provides the necessary knowledge to diagnose infective pneumonia. It covers symptoms and clinical signs, clinical history, pathogens, laboratory tests and results, imaging, differential diagnosis and pneumonia complications. The Ontology for General Medical Science (OGMS) is an ontology of entities involved in a clinical encounter. OGMS includes very general terms that are used across medical disciplines, including: 'disease', 'disorder', 'disease course', 'diagnosis', 'patient', and 'healthcare provider'. OGMS uses the Basic Formal Ontology (BFO) as an upper-level ontology. The scope of OGMS is restricted to humans, but many terms can be applied to a variety of organisms. OGMS provides a formal theory of disease that can be further elaborated by specific disease ontologies. This theory is implemented using OWL-DL and OBO Relation Ontology relations and is available in OWL and OBO formats. OGMS is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX) and the Signs, Symptoms, and Findings Workshop(Milan, Italy). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology. Ontology for General Medical Science http://creativecommons.org/licenses/by/4.0/ 1.2 The Ontology for General Medical Science (OGMS) is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology. The latest version of OGMS is available at http://purl.obolibrary.org/obo/ogms.owl The OGMS developer site is https://github.com/OGMS/ogms If you are interested in participating in the development of OGMS, please send email to baeverma The following annotation properties are used: oboInOwl:xxxxxx; Examples: - to define CUI: <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">UMLS_CUI:C9999999</oboInOwl:hasDbXref> - database_cross-reference replaced by oboInOwl:hasDbXref - altLabel replaced by oboInOwl:hasSynonym - has_exact_synonym replaced by oboInOwl:hasExactSynonym obo:IAO_xxxxxxx skos:notation (used by SYMP) The following ontologies are reused: - Basic Formal Ontology (BFO) - Ontology for General Medical Science (OGMS) - Symptoms (SYMP) - Relation Ontology (RO) - Human Phenotype Ontology (HP) - Human Disease Ontology (DOID) - Infectious Disease Ontology (IDO) - Logical Observation Identifiers Names and Codes (LOINC) - NCBI organismal classification (NCBITAXON) - Systematized Nomenclature of Medicine Clinical Terms (SNOMEDCT) - Radiology Lexicon (RADLEX) - Computer-Based Patient Record Ontology(CPRO) - Information Artifact Ontology (IAO) The following practice clinical guidelines (CPG) are reused: - https://www.idsociety.org/practice-guideline/community-acquired-pneumonia-cap-in-adults/ - https://www.idsociety.org/practice-guideline/hap_vap/ - https://www.idsociety.org/practice-guideline/community-acquired-pneumonia-cap-in-infants-and-children/ - https://www.nice.org.uk/guidance/qs110/resources/pneumonia-in-adults-pdf-75545291391685 - https://www.ncbi.nlm.nih.gov/books/NBK552669/pdf/Bookshelf_NBK552669.pdf - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094776/ - https://www.atsjournals.org/doi/full/10.1164/rccm.201908-1581ST - https://www.thoracic.org/statements/resources/tb-opi/idsaats-cap.pdf - https://www.thoracic.org/statements/guideline-implementation-tools/diagnosis-and-treatment-of-cap.php - https://www.brit-thoracic.org.uk/quality-improvement/guidelines/pneumonia-adults/ - https://www.atsjournals.org/doi/full/10.1164/rccm.200405-644ST - https://pulmccm.org/infectious-disease-sepsis-review/idsa-guidelines-2016-hap-vap-end-hcap-know-feel-fine/ - https://www.cochrane.org/CD009175/ARI_clinical-symptoms-and-signs-for-the-diagnosis-of-mycoplasma-pneumoniae-in-children-and-adolescents-with-community-acquired-pneumonia - https://www.nice.org.uk/guidance/ng165/resources/covid19-rapid-guideline-managing-suspected-or-confirmed-pneumonia-in-adults-in-the-community-pdf-66141902429125 2021-08-19 Version 2.0, 2024/07/10 Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification. Really of interest to developers only BFO OWL specification label Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2 Person:Alan Ruttenberg Really of interest to developers only BFO CLIF specification label editor preferred term The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English) PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> editor preferred term example of usage A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> example of usage in branch An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet. GROUP:OBI OBI_0000277 in branch has curation status PERSON:Alan Ruttenberg PERSON:Bill Bug PERSON:Melanie Courtot has curation status definition The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions. 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition editor note An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology. PERSON:Daniel Schober GROUP:OBI:<http://purl.obofoundry.org/obo/obi> editor note term editor Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115. PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition editor term editor alternative term An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent) PERSON:Daniel Schober GROUP:OBI:<http://purl.obolibrary.org/obo/obi> alternative term definition source Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007 PERSON:Daniel Schober Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w GROUP:OBI:<http://purl.obolibrary.org/obo/obi> definition source has obsolescence reason Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification. PERSON:Alan Ruttenberg PERSON:Melanie Courtot has obsolescence reason curator note An administrative note of use for a curator but of no use for a user PERSON:Alan Ruttenberg curator note term tracker item the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/ An IRI or similar locator for a request or discussion of an ontology term. Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg The 'tracker item' can associate a tracker with a specific ontology term. term tracker item ontology term requester The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition. Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg The 'term requester' can credit the person, organization or project who request the ontology term. ontology term requester is denotator type Relates an class defined in an ontology, to the type of it's denotator In OWL 2 add AnnotationPropertyRange('is denotator type' 'denotator type') Alan Ruttenberg is denotator type imported from For external terms/classes, the ontology from which the term was imported PERSON:Alan Ruttenberg PERSON:Melanie Courtot GROUP:OBI:<http://purl.obolibrary.org/obo/obi> imported from expand expression to ObjectProperty: RO_0002104 Label: has plasma membrane part Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones Chris Mungall expand expression to expand assertion to ObjectProperty: RO??? Label: spatially disjoint from Annotations: expand_assertion_to "DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom. Chris Mungall expand assertion to first order logic expression PERSON:Alan Ruttenberg first order logic expression antisymmetric property part_of antisymmetric property xsd:true Use boolean value xsd:true to indicate that the property is an antisymmetric property Alan Ruttenberg antisymmetric property OBO foundry unique label An alternative name for a class or property which is unique across the OBO Foundry. The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools . PERSON:Alan Ruttenberg PERSON:Bjoern Peters PERSON:Chris Mungall PERSON:Melanie Courtot GROUP:OBO Foundry <http://obofoundry.org/> OBO foundry unique label has ID digit count Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO" Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix" annotation property value concatenated with an integer in the id range (left padded with "0"s to make this many digits) Person:Alan Ruttenberg has ID digit count has ID range allocated Datatype: idrange:1 Annotations: 'has ID range allocated to': "Chris Mungall" EquivalentTo: xsd:integer[> 2151 , <= 2300] Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms Person:Alan Ruttenberg has ID range allocated to has ID policy for Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO" Relating an ontology used to record id policy to the ontology namespace whose policy it manages Person:Alan Ruttenberg has ID policy for has ID prefix Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO" Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with "0"s to make this many digits) to construct an ID for a term being created. Person:Alan Ruttenberg has ID prefix elucidation person:Alan Ruttenberg Person:Barry Smith Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms elucidation has associated axiom(nl) Person:Alan Ruttenberg Person:Alan Ruttenberg An axiom associated with a term expressed using natural language has associated axiom(nl) has associated axiom(fol) Person:Alan Ruttenberg Person:Alan Ruttenberg An axiom expressed in first order logic using CLIF syntax has associated axiom(fol) is allocated id range Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. "IAO_0020000-IAO_0020999" PERSON:Alan Ruttenberg Add as annotation triples in the granting ontology is allocated id range has ontology root term Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root. Nicolas Matentzoglu has ontology root term may be identical to A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged. David Osumi-Sutherland #40 VFB Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance. may be identical to scheduled for obsoletion on or after Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date. Chris Mungall, Jie Zheng https://github.com/geneontology/go-ontology/issues/15532 https://github.com/information-artifact-ontology/ontology-metadata/issues/32 GO ontology scheduled for obsoletion on or after has axiom id Person:Alan Ruttenberg Person:Alan Ruttenberg A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI has axiom label term replaced by Use on obsolete terms, relating the term to another term that can be used as a substitute Person:Alan Ruttenberg Person:Alan Ruttenberg Add as annotation triples in the granting ontology term replaced by If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL is a defining property chain axiom RO: 2020/12/18 If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R. is a defining property chain axiom where second argument is reflexive RO: 2020/12/18 has_obo_format_version has_related_synonym is part of my brain is part of my body (continuant parthood, two material entities) my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity) this day is part of this year (occurrent parthood) a core relation that holds between a part and its whole Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'. part_of part of http://www.obofoundry.org/ro/#OBO_REL:part_of has part my body has part my brain (continuant parthood, two material entities) my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity) this year has part this day (occurrent parthood) a core relation that holds between a whole and its part Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part. Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'. has_part has part precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. This object property has been extracted from Relation Ontology (RO). precedes RO: 2020/12/18 occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t occurs_in unfolds in unfolds_in Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant This object property has been extracted from Relation Ontology (RO). occurs in RO: 2020/12/18 site of [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant This object property has been extracted from Relation Ontology (RO). contains process RO: 2020/12/18 A relation that holds between a disease "A" and another disease "B" that develops in the course of the disease "A". PNADO:0000001 Complication of disease A relation that holds between a function "A" and another disease "B" that develops in the course of the disease "A". PNADO:0000002 Complication of function A relation that holds between a procedure "A" and another disease "B" that develops in the course of the disease "A". PNADO:0000004 Complication of procedure A relation that holds between a treatment "A" and another disease "B" that develops in the course of the disease "A". PNADO:0000010 Complication of treatment A relation that holds between a patient and a symptom. PNADO:0000034 Has symptom A relation that holds between a physical examination and a physical sign. PNADO:0000366 Finding of A relation that holds between a diagnosis A and a disease B. PNADO:0001121 Is diagnosis of A relation that holds between a patient and a disease. PNADO:0001156 Has clinical history A relation that holds between a diagnosis 'A' and a diagnosis 'B'. The diagnosis 'B' has similar clinical features as diagnosis 'A'. Example: interstitial lung diagnosis is a differential diagnosis of pneumonia if at any point in time they have similar clinical features. PNADO:0001157 Differential diagnosis of A relation that holds between a disease (or function or procedure or treatment) “A” and another disease “B” that develops in the course of the disease “A”. PNADO:0001289 Complication of A relation that holds between antigen test and pathogen. An antigen test 'A' detects a pathogen 'B' when it determines its presence (or not). PNADO:0001290 Detects A relation that holds between a patient and a diagnostic process. Example, a patient 'A' has microbiologicals tests. PNADO:0001292 Has diagnostic process A relation thats holds between a patient and a physical sign. PNADO:0001294 Has physical sign inheres in this fragility inheres in this vase this red color inheres in this apple a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence A dependent inheres in its bearer at all times for which the dependent exists. inheres_in inheres in RO: 2020/12/18 bearer of this apple is bearer of this red color this vase is bearer of this fragility A relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence. A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist. bearer_of is bearer of bearer of RO: 2020/12/18 this blood coagulation has participant this blood clot this investigation has participant this investigator this process has participant this input material (or this output material) a relation between a process and a continuant, in which the continuant is somehow involved in the process RO:0000057 has participant RO: 2020/12/18 This person has role this investigator role (more colloquially: this person has this role of investigator). A relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence. A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists. has_role has role RO: 2020/12/18 a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence has disposition RO: 2020/12/18 inverse of has disposition disposition of RO: 2020/12/18 David Osumi-Sutherland ends_at_start_of meets X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) immediately precedes RO: 2020/12/18 David Osumi-Sutherland io X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y)) starts during RO: 2020/12/18 David Osumi-Sutherland d during X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y)) happens during RO: 2020/12/18 David Osumi-Sutherland o overlaps X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). ends during RO: 2020/12/18 x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y) overlaps RO: 2020/12/18 true Chris Mungall Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends. https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. temporally related to RO: 2020/12/18 Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall started by starts with RO: 2020/12/18 x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. Chris Mungall finished by ends with RO: 2020/12/18 q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w. Because part_of is transitive, inheres in is a sub-relation of inheres in part of Chris Mungall inheres in part of RO: 2020/12/18 true A mereological relationship or a topological relationship Chris Mungall Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships mereotopologically related to RO: 2020/12/18 This relation groups causal relations between material entities and causal relations between processes This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yield a cross-product of different relation types. Chris Mungall Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect. causally related to RO: 2020/12/18 Chris Mungall depends on RO: 2020/12/18 The genetic variant 'NM_007294.3(BRCA1):c.110C>A (p.Thr37Lys)' casues or contributes to the disease 'familial breast-ovarian cancer'. An environment of exposure to arsenic causes or contributes to the phenotype of patchy skin hyperpigmentation, and the disease 'skin cancer'. A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition. Note that relationships of phenotypes to organisms/strains that bear them, or diseases they are manifest in, should continue to use RO:0002200 ! 'has phenotype' and RO:0002201 ! 'phenotype of'. Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions. causes or contributes to condition RO: 2020/12/18 A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition. causes condition RO: 2020/12/18 A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition. contributes to condition RO: 2020/12/18 a data property that relates an individual patient to the literal string that represents the patient's id patient ID UMLS:C4699166 UMLS:T033 LNC:LA24772-8 Lactic acidosis in blood LNC: 2020/02/11 LNC:LA24772-8 UMLS:C4489207 LNC:LA26738-7 No urine output (e.g., renal failure) LNC: 2020/02/11 LNC:LA26738-7 UMLS:C1291218 LNC:LP14492-0 Urea nitrogen LNC: 2020/02/11 LNC:LP14492-0 LOINC: pH is a measure of the acidity or basicity of a solution. It is defined as the cologarithm of dissolved hydrogen ions (H+). Hydrogen ion activity coefficients cannot be measured experimentally, so they are based on theoretical calculations. The pH scale is not an absolute one, it is relative to a set of internationally established standard solutions. pH 7.0 is considered neutral. UMLS:C0020283 LNC:LP14752-7 pH LNC: 2020/02/11 LNC:LP14752-7 The measure of the level of heat of a human or animal. (MSH) SNOMEDCT_US:386725007 UMLS:C0005903 LNC:LP29701-7 Body temperature LNC: 2020/02/11 LNC:LP29701-7 An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). (MSH) UMLS:C1305855 LNC:LP35925-4 Body mass index LNC: 2020/02/11 LNC:LP35925-4 UMLS:C5166429 LNC:LP408317-8 Heart rate | Blood Postductal | Cardiopulmonary LNC: 2020/02/11 LNC:LP408317-8 UMLS:C5166430 LNC:LP408318-6 Heart rate | Blood Preductal | Cardiopulmonary LNC: 2020/02/11 LNC:LP408318-6 UMLS:C5214360 LNC:LP415677-6 Body mass index (BMI) | Patient | General body weight LNC: 2020/02/11 LNC:LP415677-6 UMLS:C5213465 LNC:LP415755-0 Heart rate | Arterial system | General heart rate LNC: 2020/02/11 LNC:LP415755-0 UMLS:C5213473 LNC:LP415756-8 Heart rate | XXX | General heart rate LNC: 2020/02/11 LNC:LP415756-8 UMLS:C5213467 LNC:LP415780-8 Heart rate | Arterial system | Specific heart rate LNC: 2020/02/11 LNC:LP415780-8 UMLS:C5213468 LNC:LP415781-6 Heart rate | Capillary bed | Specific heart rate LNC: 2020/02/11 LNC:LP415781-6 UMLS:C5213469 LNC:LP415782-4 Heart rate | Cardiac apex | Specific heart rate LNC: 2020/02/11 LNC:LP415782-4 UMLS:C5213470 LNC:LP415783-2 Heart rate | Heart | Specific heart rate LNC: 2020/02/11 LNC:LP415783-2 UMLS:C5213471 LNC:LP415784-0 Heart rate | Intra arterial line | Specific heart rate LNC: 2020/02/11 LNC:LP415784-0 UMLS:C5213472 LNC:LP415785-7 Heart rate | Peripheral artery | Specific heart rate LNC: 2020/02/11 LNC:LP415785-7 UMLS:C5213475 LNC:LP415786-5 Heart rate | XXX | Specific heart rate LNC: 2020/02/11 LNC:LP415786-5 UMLS:C5214408 LNC:LP415787-3 Heart rate | Fetus | Specific heart rate LNC: 2020/02/11 LNC:LP415787-3 UMLS:C5213476 LNC:LP415805-3 Heart rate | XXX | Timed specific heart rate LNC: 2020/02/11 LNC:LP415805-3 UMLS:C5213466 LNC:LP416415-0 Heart rate | Arterial system | Heart rate taken in specific position LNC: 2020/02/11 LNC:LP416415-0 UMLS:C5213474 LNC:LP416416-8 Heart rate | XXX | Heart rate taken in specific position LNC: 2020/02/11 LNC:LP416416-8 The number of times the HEART VENTRICLES contract per unit of time, usually per minute. (MSH) SNOMEDCT_US:364075005 UMLS:C0018810 LNC:LP72677-5 Heart rate LNC: 2020/02/11 LNC:LP72677-5 A type of protein found in blood, egg white, milk, and other substances. (NCI) UMLS:C0001924 LNC:MTHU001929 Albumin LNC: 2020/02/11 LNC:MTHU001929 UMLS:C1542867 BMI Body mass index (BMI) [Ratio] Body mass index:Ratio:Point in time:^Patient:Quantitative LNC:39156-5 Body mass index:Ratio:Pt:^Patient:Qn LNC: 2020/02/11 LNC:39156-5 UMLS:C4696581 BMI Est Body mass index (BMI) [Ratio] Estimated Body mass index:Ratio:Point in time:^Patient:Quantitative:Estimated LNC:89270-3 Body mass index:Ratio:Pt:^Patient:Qn:Estimated LNC: 2020/02/11 LNC:89270-3 UMLS:C3343149 NCBITAXON:1008944 Candidatus rohrkolberia NCBITAXON: 2020/02/11 NCBITAXON:1008944 UMLS:C0042776 Vira NCBITAXON:10239 Viruses NCBITAXON: 2020/02/11 NCBITAXON:10239 UMLS:C0019369 NCBITAXON_10292 Herpesviridae NCBITAXON: 2020/02/11 NCBITAXON_10292 NCBITAXON_10293 Alphaherpesvirinae NCBITAXON: 2020/02/11 NCBITAXON_10293 UMLS:C0206558 NCBITAXON_10294 Simplexvirus NCBITAXON: 2020/02/11 NCBITAXON_10294 UMLS:C0206559 NCBITAXON_10319 Varicellovirus NCBITAXON: 2020/02/11 NCBITAXON_10319 UMLS:C0042338 Human herpes virus 3 Human herpesvirus 3 Varicella Zoster Virus varicella zoster virus VZV varicella-zoster virus VZV NCBITAXON_10335 Human alphaherpesvirus 3 NCBITAXON: 2020/02/11 NCBITAXON_10335 UMLS:C3362409 NCBITAXON:1048757 Candidatus moranella NCBITAXON: 2020/02/11 NCBITAXON:1048757 UMLS:C3389304 NCBITAXON:1081630 Candidatus schneideria NCBITAXON: 2020/02/11 NCBITAXON:1081630 UMLS:C0010076 NCBITaxon:11118 Coronaviridae NCBITAXON: 2020/02/11 NCBITaxon:11118 UMLS:C3412572 NCBITAXON:1113537 Chlamydia/chlamydophila group NCBITAXON: 2020/02/11 NCBITAXON:1113537 UMLS:C1052641 NCBITAXON:111527 Pseudomallei group NCBITAXON: 2020/02/11 NCBITAXON:111527 UMLS:C0206531 NCBITAXON:11157 Mononegavirales NCBITAXON: 2020/02/11 NCBITAXON:11157 A subfamily of PARAMYXOVIRIDAE containing two genera: PNEUMOVIRUS; and METAPNEUMOVIRUS. (MSH) UMLS:C0206534 Pneumovirinae NCBITAXON:11244 Pneumoviridae NCBITAXON: 2020/02/11 NCBITAXON:11244 UMLS:C0206543 NCBITAXON:11245 Pneumovirus NCBITAXON: 2020/02/11 NCBITAXON:11245 UMLS:C0029341 NCBITAXON:11308 Orthomyxoviridae NCBITAXON: 2020/02/11 NCBITAXON:11308 UMLS:C3719304 NCBITAXON:1131492 Aspergillaceae NCBITAXON: 2020/02/11 NCBITAXON:1131492 UMLS:C0029347 Influenza virus type A Human Influenza A Virus Influenza virus type A NCBITAXON:11320 Influenza A virus NCBITAXON: 2020/02/11 NCBITAXON:11320 UMLS:C3441987 NCBITAXON:1159901 Deltacoronavirus NCBITAXON: 2020/02/11 NCBITAXON:1159901 UMLS:C3560566 NCBITAXON:1177214 Candidatus profftia NCBITAXON: 2020/02/11 NCBITAXON:1177214 UMLS:C3560569 NCBITAXON:1177217 Candidatus gillettellia NCBITAXON: 2020/02/11 NCBITAXON:1177217 UMLS:C1056978 NCBITAXON:118968 Coxiellaceae NCBITAXON: 2020/02/11 NCBITAXON:118968 UMLS:C1056979 Legionellaceae group NCBITAXON:118969 Legionellales NCBITAXON: 2020/02/11 NCBITAXON:118969 UMLS:C1057057 Burkholderia group NCBITAXON:119060 Burkholderiaceae NCBITAXON: 2020/02/11 NCBITAXON:119060 A phylum of bacteria consisting of the purple bacteria and their relatives which form a branch of the eubacterial tree. This group of predominantly gram-negative bacteria is classified based on homology of equivalent nucleotide sequences of 16S ribosomal RNA or by hybridization of ribosomal RNA or DNA with 16S and 23S ribosomal RNA. (MSH) UMLS:C0751985 Alphaproteobacteraeota Alphaproteobacteriota purple bacteria purple bacteria and relatives purple non-sulfur bacteria purple photosynthetic bacteria purple photosynthetic bacteria and relatives NCBITAXON:1224 Proteobacteria NCBITAXON: 2020/02/11 NCBITAXON:1224 A group of the proteobacteria comprised of facultatively anaerobic and fermentative gram-negative bacteria. (MSH) UMLS:C0751988 Proteobacteria gamma subdivision Purple bacteria, gamma subdivision gamma proteobacteria gamma subdivision gamma subgroup NCBITAXON:1236 Gammaproteobacteria NCBITAXON: 2020/02/11 NCBITAXON:1236 A taxonomic phylum within kingdom Bacteria consisting of mostly gram-positive bacteria with a low G+C ratio. The phylum is highly diverse in phenotypic characteristics. (NCI) UMLS:C1254144 Bacillaeota Bacillus/Clostridium group Clostridium group firmicutes Firmacutes Low G+C firmicutes clostridial firmicutes low G+C Gram-positive bacteria NCBITAXON:1239 Firmicutes NCBITAXON: 2020/02/11 NCBITAXON:1239 Aurococcus NCBITAXON:1279 Staphylococcus NCBITAXON: 2020/02/11 NCBITAXON:1279 Staphylococcus pyogenes aureus NCBITAXON_1280 Staphylococcus aureus NCBITAXON: 2020/02/11 NCBITAXON_1280 UMLS:C0035236 respiratory syncytial virus RS respiratory syncytial virus RS virus respiratory syncytial virus RSV NCBITAXON:12814 Respiratory syncytial virus NCBITAXON: 2020/02/11 NCBITAXON:12814 UMLS:C0038394 NCBITAXON:1300 Streptococcaceae NCBITAXON: 2020/02/11 NCBITAXON:1300 UMLS:C0038402 NCBITAXON:1301 Streptococcus NCBITAXON: 2020/02/11 NCBITAXON:1301 UMLS:C0038410 Diplococcus pneumoniae Micrococcus pneumoniae Pneumococci Pneumococcus NCBITAXON:1313 Streptococcus pneumoniae NCBITAXON: 2020/02/11 NCBITAXON:1313 UMLS:C3636939 NCBITAXON:1330545 Lelliottia NCBITAXON: 2020/02/11 NCBITAXON:1330545 UMLS:C3636940 NCBITAXON:1330546 Pluralibacter NCBITAXON: 2020/02/11 NCBITAXON:1330546 UMLS:C3636941 NCBITAXON:1330547 Kosakonia NCBITAXON: 2020/02/11 NCBITAXON:1330547 UMLS:C3741107 NCBITAXON:1335483 Shimwellia NCBITAXON: 2020/02/11 NCBITAXON:1335483 UMLS:C1064844 unclassified Coxiella group NCBITAXON:134284 Unclassified coxiellaceae NCBITAXON: 2020/02/11 NCBITAXON:134284 UMLS:C0033807 NCBITAXON:135621 Pseudomonadaceae NCBITAXON: 2020/02/11 NCBITAXON:135621 UMLS:C1065478 Pasteruellaceae group NCBITAXON:135625 Pasteurellales NCBITAXON: 2020/02/11 NCBITAXON:135625 UMLS:C3751140 NCBITAXON:1356488 Rosenbergiella NCBITAXON: 2020/02/11 NCBITAXON:1356488 UMLS:C1066168 NCBITAXON:136841 Pseudomonas aeruginosa group NCBITAXON: 2020/02/11 NCBITAXON:136841 An order of gram-positive bacteria in the class Bacilli, phylum Firmicutes. (MSH) UMLS:C1456435 Bacillus/Staphylococcus group NCBITAXON:1385 Bacillales NCBITAXON: 2020/02/11 NCBITAXON:1385 A genus of BACILLACEAE that are spore-forming, rod-shaped cells. Most species are saprophytic soil forms with only a few species being pathogenic. (MSH) A genus of bacteria within the phylum Firmicutes consisting of gram-positive bacilli that are either obligate or facultative aerobes, and test positive for the enzyme catalase. (NCI) genus of bacillaceae that are spore forming, rod shaped cells; most species are saprophytic soil forms with only a few species being pathogenic. (CSP) UMLS:C0004587 Bacillus rRNA group 1 NCBITAXON:1386 Bacillus NCBITAXON: 2020/02/11 NCBITAXON:1386 A species of aerobic or facultatively anaerobic, Gram-positive, rod shaped bacteria assigned to the phylum Firmicutes. This species is nonmotile, spore forming, and catalase positive, hydrolyzes casein, starch and gelatin, reduces nitrate, is penicillin susceptible but cephalosporin resistant, gamma phage sensitive, has absent or delayed hemolysis and the capsule can be visualized using M'Faydean's stain. B. anthracis is found in most soil, causes Anthrax in humans and animals, has been utilized as a biological weapon and both a veterinary and human vaccine exists. (NCI) A species of bacteria that causes ANTHRAX in humans and animals. (MSH) causes anthrax in humans and animals. (CSP) UMLS:C0004589 Anthrax bacterium Bacillus cereus var. anthracis Bacteridium anthracis NCBITAXON:1392 Bacillus anthracis NCBITAXON: 2020/02/11 NCBITAXON:1392 NCI | A species of facultatively anaerobic, Gram-positive, rod shaped bacteria assigned to the phylum Firmicutes. This species is nonmotile, spore forming, catalase positive, oxidase negative, and hydrolyzes starch, gelatin, and oxidase. B. mycoides is found in soil. NCI | Any bacterial organism that can be assigned to the species Bacillus mycoides. UMLS:C0314899 NCBITAXON:1405 Bacillus mycoides NCBITAXON: 2020/02/11 NCBITAXON:1405 UMLS:C1070970 Euascomycota NCBITAXON:147538 Pezizomycotina NCBITAXON: 2020/02/11 NCBITAXON:147538 UMLS:C1070975 NCBITAXON:147545 Eurotiomycetes NCBITAXON: 2020/02/11 NCBITAXON:147545 UMLS:C3932967 NCBITAXON:1485663 Candidatus aschnera NCBITAXON: 2020/02/11 NCBITAXON:1485663 UMLS:C3945380 NCBITAXON:1504576 Pseudocitrobacter NCBITAXON: 2020/02/11 NCBITAXON:1504576 UMLS:C0315214 NCBITAXON:158483 Cedecea NCBITAXON: 2020/02/11 NCBITAXON:158483 UMLS:C0445757 NCBITAXON:158851 Trabulsiella NCBITAXON: 2020/02/11 NCBITAXON:158851 UMLS:C0317467 NCBITAXON:158876 Yokenella NCBITAXON: 2020/02/11 NCBITAXON:158876 UMLS:C1076664 NCBITAXON:160674 Raoultella NCBITAXON: 2020/02/11 NCBITAXON:160674 UMLS:C4103583 NCBITAXON:1649295 Franconibacter NCBITAXON: 2020/02/11 NCBITAXON:1649295 UMLS:C4103582 NCBITAXON:1649298 Siccibacter NCBITAXON: 2020/02/11 NCBITAXON:1649298 UMLS:C4137402 Berkiella NCBITAXON:1755683 Candidatus berkiella NCBITAXON: 2020/02/11 NCBITAXON:1755683 A family of gram-positive bacteria found in soil and dairy products and as parasites on animals and man. Several are important pathogens. (MSH) A taxonomic family of bacterium in the phylum Actinobacteria that includes the genus Mycobacterium, among others. (NCI) UMLS:C0026907 NCBITAXON:1762 Mycobacteriaceae NCBITAXON: 2020/02/11 NCBITAXON:1762 A genus of acid-fast Gram-positive, aerobic and nonmotile bacteria in the phylum Actinobacteria. (NCI) A genus of gram-positive, aerobic bacteria. Most species are free-living in soil and water, but the major habitat for some is the diseased tissue of warm-blooded hosts. (MSH) UMLS:C0026912 NCBITAXON:1763 Mycobacterium NCBITAXON: 2020/02/11 NCBITAXON:1763 A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. (MSH) An obligate anaerobic, weakly Gram-positive species of mycobacterium that is the cause of most cases of tuberculosis. (NCI) species of gram positive, aerobic bacteria that produces tuberculosis in man, other primates, dogs, and some animals which have contact with man; growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. (CSP) UMLS:C0026926 Bacillus tuberculosis Bacterium tuberculosis Mycobacterium tuberculosis typus humanus Mycobacterium tuberculosis var. hominis NCBITAXON:1773 Mycobacterium tuberculosis NCBITAXON: 2020/02/11 NCBITAXON:1773 UMLS:C4129059 NCBITAXON:1780190 Izhakiella NCBITAXON: 2020/02/11 NCBITAXON:1780190 UMLS:C4128736 NCBITAXON:1783257 PVC group NCBITAXON: 2020/02/11 NCBITAXON:1783257 UMLS:C4128729 NCBITAXON:1783272 Terrabacteria group NCBITAXON: 2020/02/11 NCBITAXON:1783272 UMLS:C4122799 NCBITAXON:1798566 Unclassified legionellaceae NCBITAXON: 2020/02/11 NCBITAXON:1798566 UMLS:C4369937 NCBITAXON:1822002 Enterobacillus NCBITAXON: 2020/02/11 NCBITAXON:1822002 A family of bacteria which produce endospores. They are mostly saprophytes from soil, but a few are insect or animal parasites or pathogens. (MSH) family of bacteria which produce endospores; they are mostly saprophytes from soil, but a few are insect or animal parasites or pathogens. (CSP) UMLS:C0004586 NCBITAXON:186817 Bacillaceae NCBITAXON: 2020/02/11 NCBITAXON:186817 UMLS:C1210581 NCBITAXON:186826 Lactobacillales NCBITAXON: 2020/02/11 NCBITAXON:186826 UMLS:C4429606 NCBITAXON:1903434 Atlantibacter NCBITAXON: 2020/02/11 NCBITAXON:1903434 UMLS:C4680631 NCBITAXON:1903473 Atlantibacter Sp. NCBITAXON: 2020/02/11 NCBITAXON:1903473 UMLS:C1006474 NCBITAXON:191675 Unclassified enterobacteriaceae NCBITAXON: 2020/02/11 NCBITAXON:191675 UMLS:C4450085 NCBITAXON:1944125 Aspergillago NCBITAXON: 2020/02/11 NCBITAXON:1944125 UMLS:C0949936 influenzavirus A NCBITAXON:197911 Alphainfluenzavirus NCBITAXON: 2020/02/11 NCBITAXON:197911 UMLS:C4576541 NCBITaxon:1986197 unclassified Coronaviridae NCBITAXON: 2020/02/11 NCBITaxon:1986197 A unicellular, prokaryotic organism that reproduces by cell division and usually has cell walls; can be shaped like spheres, rods, or spirals; and can be found in virtually any environment. (NCI) UMLS:C0004611 NCBITAXON:2 Bacteria NCBITAXON: 2020/02/11 NCBITAXON:2 UMLS:C1456432 Actinobacteraeota NCBITAXON:201174 Actinobacteria NCBITAXON: 2020/02/11 NCBITAXON:201174 UMLS:C4680288 NCBITAXON:2026190 Bacillus mobilis NCBITAXON: 2020/02/11 NCBITAXON:2026190 UMLS:C4605394 NCBITAXON:2026194 Bacillus paramycoides NCBITAXON: 2020/02/11 NCBITAXON:2026194 UMLS:C1532554 Chlamydaeota Chlamydiota NCBITAXON:204428 Chlamydiae NCBITAXON: 2020/02/11 NCBITAXON:204428 UMLS:C3463900 NCBITAXON:204429 Chlamydiia NCBITAXON: 2020/02/11 NCBITAXON:204429 UMLS:C4619721 NCBITAXON:2055876 Metakosakonia NCBITAXON: 2020/02/11 NCBITAXON:2055876 UMLS:C4619722 NCBITAXON:2055880 Pseudescherichia NCBITAXON: 2020/02/11 NCBITAXON:2055880 UMLS:C0026944 Borrelomycetales Mollicutales Mycoplasmas Paramycetales Pleuropneumoniales The Mycoplasmas NCBITAXON:2085 Mycoplasmatales NCBITAXON: 2020/02/11 NCBITAXON:2085 UMLS:C0026943 Borrelomycetaceae Parasitaceae Pleuropneumoniaceae NCBITAXON:2092 Mycoplasmataceae NCBITAXON: 2020/02/11 NCBITAXON:2092 A genus of gram-negative, mostly facultatively anaerobic bacteria in the family MYCOPLASMATACEAE. The cells are bounded by a PLASMA MEMBRANE and lack a true CELL WALL. Its organisms are pathogens found on the MUCOUS MEMBRANES of humans, ANIMALS, and BIRDS. (MSH) UMLS:C0026934 Asteromyces Borrelomyces Bovimyces Eperythrozoon Haemobartonella Pleuropneumonia NCBITAXON:2093 Mycoplasma NCBITAXON: 2020/02/11 NCBITAXON:2093 Short filamentous organism of the genus Mycoplasma, which binds firmly to the cells of the respiratory epithelium. It is one of the etiologic agents of non-viral primary atypical pneumonia in man. (MSH) UMLS:C0026941 Filterable agent of primary atypical pneumonia Schizoplasma pneumoniae NCBITAXON:2104 Mycoplasma pneumoniae NCBITAXON: 2020/02/11 NCBITAXON:2104 UMLS:C4675266 NCBITAXON:2133750 Unclassified pneumovirus NCBITAXON: 2020/02/11 NCBITAXON:2133750 UMLS:C5066076 NCBITAXON:2497569 Negarnaviricota NCBITAXON: 2020/02/11 NCBITAXON:2497569 UMLS:C5066077 NCBITAXON:2497570 Haploviricotina NCBITAXON: 2020/02/11 NCBITAXON:2497570 UMLS:C5066078 NCBITAXON:2497571 Polyploviricotina NCBITAXON: 2020/02/11 NCBITAXON:2497571 UMLS:C5066081 NCBITAXON:2497574 Monjiviricetes NCBITAXON: 2020/02/11 NCBITAXON:2497574 UMLS:C5066084 NCBITAXON:2497577 Insthoviricetes NCBITAXON: 2020/02/11 NCBITAXON:2497577 UMLS:C5067293 NCBITaxon:2499399 Cornidovirineae NCBITAXON: 2020/02/11 NCBITaxon:2499399 UMLS:C5067303 NCBITAXON:2499411 Articulavirales NCBITAXON: 2020/02/11 NCBITAXON:2499411 UMLS:C5069007 NCBITaxon:2501931 Orthocoronavirinae NCBITAXON: 2020/02/11 NCBITaxon:2501931 UMLS:C5074702 NCBITAXON:2509511 Sarbecovirus NCBITAXON: 2020/02/11 NCBITAXON:2509511 UMLS:C1474469 NCBITAXON:254245 Aquicella NCBITAXON: 2020/02/11 NCBITAXON:254245 UMLS:C1494915 NCBITAXON:255519 Atlantibacter subterranea NCBITAXON: 2020/02/11 NCBITAXON:255519 UMLS:C0035691 RNA viruses RNA viruses and viroids NCBITaxon:2559587 Riboviria NCBITAXON: 2020/02/11 NCBITaxon:2559587 The lone genus of bacteria in the family Francisellaceae, frequently found in natural waters. It can be parasitic in humans, other MAMMALS; BIRDS; and ARTHROPODS. (MSH) UMLS:C0016676 NCBITAXON:262 Francisella NCBITAXON: 2020/02/11 NCBITAXON:262 UMLS:C0684063 eukaryotes Eucarya Eucaryotae Eukarya Eukaryotae Eukaryotes NCBITAXON:2759 Eukaryota NCBITAXON: 2020/02/11 NCBITAXON:2759 UMLS:C0751987 Proteobacteria beta subdivision Purple bacteria, beta subdivision beta proteobacteria beta subdivision beta subgroup NCBITAXON:28216 Betaproteobacteria NCBITAXON: 2020/02/11 NCBITAXON:28216 UMLS:C0033819 Loefflerella pseudomallei NCBITAXON:28450 Burkholderia pseudomallei NCBITAXON: 2020/02/11 NCBITAXON:28450 family of gram-negative bacteria usually found in soil or water and including many plant pathogens and a few animal pathogens. (MSH) UMLS:C0033808 Liquidomonas Loefflerella RNA similarity group I NCBITAXON:286 Pseudomonas NCBITAXON: 2020/02/11 NCBITAXON:286 UMLS:C0033809 Bacillus aeruginosus Bacillus pyocyaneus Bacterium aeruginosum Bacterium pyocyaneum Micrococcus pyocyaneus P. aeruginosa Pseudomonas polycolor Pseudomonas pyocyanea NCBITAXON:287 Pseudomonas aeruginosa NCBITAXON: 2020/02/11 NCBITAXON:287 UMLS:C3179193 NCBITAXON:31969 Mollicutes NCBITAXON: 2020/02/11 NCBITAXON:31969 UMLS:C0282676 Pseudomonas RNA homology group II NCBITAXON:32008 Burkholderia NCBITAXON: 2020/02/11 NCBITAXON:32008 UMLS:C1004365 Fungi/Metazoa group opisthokonts NCBITAXON:33154 Opisthokonta NCBITAXON: 2020/02/11 NCBITAXON:33154 A taxonomic family of Gram negative, aerobic bacterium in the phylum Proteobacteria that includes the genus Francisella. (NCI) UMLS:C1004850 Francisella group NCBITAXON:34064 Francisellaceae NCBITAXON: 2020/02/11 NCBITAXON:34064 UMLS:C1947774 NCBITAXON:400524 candidatus macropleicola NCBITAXON: 2020/02/11 NCBITAXON:400524 UMLS:C1885664 NCBITAXON:401618 Candidatus riesia NCBITAXON: 2020/02/11 NCBITAXON:401618 UMLS:C1889462 NCBITAXON:409304 Candidatus ishikawaella NCBITAXON: 2020/02/11 NCBITAXON:409304 UMLS:C1894384 NCBITAXON:413496 Cronobacter NCBITAXON: 2020/02/11 NCBITAXON:413496 UMLS:C1912454 NCBITAXON:442155 Candidatus stammerula NCBITAXON: 2020/02/11 NCBITAXON:442155 UMLS:C0085465 NCBITAXON:444 Legionellaceae NCBITAXON: 2020/02/11 NCBITAXON:444 UMLS:C0023237 NCBITAXON:445 Legionella NCBITAXON: 2020/02/11 NCBITAXON:445 UMLS:C0023238 NCBITAXON:446 Legionella pneumophila NCBITAXON: 2020/02/11 NCBITAXON:446 UMLS:C2988196 NCBITAXON:451512 Mangrovibacter NCBITAXON: 2020/02/11 NCBITAXON:451512 UMLS:C2283981 NCBITAXON:451864 Dikarya NCBITAXON: 2020/02/11 NCBITAXON:451864 UMLS:C1960229 NCBITAXON:451871 Eurotiomycetidae NCBITAXON: 2020/02/11 NCBITAXON:451871 UMLS:C4122799 NCBITAXON:45616 Unclassified legionellales NCBITAXON: 2020/02/11 NCBITAXON:45616 UMLS:C0995355 NCBITAXON:461 Fluoribacter NCBITAXON: 2020/02/11 NCBITAXON:461 UMLS:C0995356 NCBITAXON:465 Tatlockia NCBITAXON: 2020/02/11 NCBITAXON:465 UMLS:C2291786 NCBITAXON:466108 Biostraticola NCBITAXON: 2020/02/11 NCBITAXON:466108 UMLS:C0995357 Acinetobacteraceae Branhamaceae NCBITAXON:468 Moraxellaceae NCBITAXON: 2020/02/11 NCBITAXON:468 UMLS:C0026536 Diplobacillus NCBITAXON:475 Moraxella NCBITAXON: 2020/02/11 NCBITAXON:475 MSH | A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies. UMLS:C0016832 NCBITAXON:4751 Fungi NCBITAXON: 2020/02/11 NCBITAXON:4751 UMLS:C0006132 Branhamella catarrhalis Mikrokkokus catarrhalis NCBITAXON:480 Moraxella catarrhalis NCBITAXON: 2020/02/11 NCBITAXON:480 UMLS:C0003965 NCBITAXON:4890 Ascomycota NCBITAXON: 2020/02/11 NCBITAXON:4890 UMLS:C0997424 Elaphomycetales Elaphomycetales NCBITAXON:5042 Eurotiales NCBITAXON: 2020/02/11 NCBITAXON:5042 UMLS:C0004034 Petromyces NCBITAXON:5052 Aspergillus NCBITAXON: 2020/02/11 NCBITAXON:5052 UMLS:C0008154 NCBITAXON:51291 Chlamydiales NCBITAXON: 2020/02/11 NCBITAXON:51291 UMLS:C0014346 NCBITAXON:543 Enterobacteriaceae NCBITAXON: 2020/02/11 NCBITAXON:543 UMLS:C0008862 NCBITAXON:544 Citrobacter NCBITAXON: 2020/02/11 NCBITAXON:544 A phylum of gram-negative bacteria consisting of cells bounded by a plasma membrane. Its organisms differ from other bacteria in that they are devoid of cell walls. This phylum was formerly the class Mollicutes. Mollicutes is now the sole class in the phylum Tenericutes. (MSH) A taxonomic phylum within kingdom Bacteria consisting of the Mollicutes, a class of intracellular parasitic bacteria without a cell wall. (NCI) UMLS:C0026390 NCBITAXON:544448 Tenericutes NCBITAXON: 2020/02/11 NCBITAXON:544448 UMLS:C0014344 NCBITAXON:547 Enterobacter NCBITAXON: 2020/02/11 NCBITAXON:547 UMLS:C2647999 NCBITAXON_548681 Herpesvirales NCBITAXON: 2020/02/11 NCBITAXON_548681 UMLS:C0014833 NCBITAXON:561 Escherichia NCBITAXON: 2020/02/11 NCBITAXON:561 UMLS:C0315244 CDC Enteric Group 11 Enterobacter hermanii Escherichia hermannii NCBITAXON:565 Atlantibacter hermannii NCBITAXON: 2020/02/11 NCBITAXON:565 UMLS:C0022727 NCBITAXON:570 Klebsiella NCBITAXON: 2020/02/11 NCBITAXON:570 UMLS:C0001699 NCBITAXON:573 Klebsiella pneumoniae NCBITAXON: 2020/02/11 NCBITAXON:573 UMLS:C0315266 NCBITAXON:579 Kluyvera NCBITAXON: 2020/02/11 NCBITAXON:579 UMLS:C1020499 NCBITAXON:57962 Candidatus Phlomobacter NCBITAXON: 2020/02/11 NCBITAXON:57962 UMLS:C2662208 Bacillus cytotoxis NCBITAXON:580165 Bacillus cytotoxicus NCBITAXON: 2020/02/11 NCBITAXON:580165 UMLS:C0036111 NCBITAXON:590 Salmonella NCBITAXON: 2020/02/11 NCBITAXON:590 UMLS:C0318319 NCBITAXON:59195 Rickettsiella NCBITAXON: 2020/02/11 NCBITAXON:59195 UMLS:C0036953 NCBITAXON:620 Shigella NCBITAXON: 2020/02/11 NCBITAXON:620 UMLS:C2804957 NCBITAXON:690591 Candidatus curculioniphilus NCBITAXON: 2020/02/11 NCBITAXON:690591 UMLS:C2806446 NCBITaxon:693995 Coronavirinae NCBITAXON: 2020/02/11 NCBITaxon:693995 UMLS:C2806447 Coronavirus group 1 Group 1 species NCBITAXON:693996 Alphacoronavirus NCBITAXON: 2020/02/11 NCBITAXON:693996 UMLS:C2806453 Coronavirus group 2 Group 2 species NCBITAXON:694002 Betacoronavirus NCBITAXON: 2020/02/11 NCBITAXON:694002 UMLS:C1175743 Human coronavirus (strain SARS) SARS coronavirus SARS virus SARS-like coronavirus SARS-related coronavirus Severe acute respiratory syndrome coronavirus NCBITAXON:694009 Severe acute respiratory syndrome-related coronavirus NCBITAXON: 2020/02/11 NCBITAXON:694009 UMLS:C2806460 Coronavirus group 3 Group 3 species NCBITAXON:694013 Gammacoronavirus NCBITAXON: 2020/02/11 NCBITAXON:694013 A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA. (MSH) UMLS:C0030641 NCBITAXON:712 Pasteurellaceae NCBITAXON: 2020/02/11 NCBITAXON:712 UMLS:C2817275 NCBITAXON:716545 saccharomyceta NCBITAXON: 2020/02/11 NCBITAXON:716545 UMLS:C2817276 NCBITAXON:716546 leotiomyceta NCBITAXON: 2020/02/11 NCBITAXON:716546 UMLS:C1029226 Thiomicrospira group Thiothrix/Francisella group NCBITAXON:72273 Thiotrichales NCBITAXON: 2020/02/11 NCBITAXON:72273 UMLS:C0682468 Pseudomonaceae/Moraxellaceae group NCBITAXON:72274 Pseudomonadales NCBITAXON: 2020/02/11 NCBITAXON:72274 A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile. (MSH) UMLS:C0018479 NCBITAXON:724 Haemophilus NCBITAXON: 2020/02/11 NCBITAXON:724 UMLS:C0949858 NCBITaxon:76804 Nidovirales NCBITAXON: 2020/02/11 NCBITaxon:76804 UMLS:C0010239 Burnetia NCBITAXON:776 Coxiella NCBITAXON: 2020/02/11 NCBITAXON:776 A group of four closely related tuberculosis-causing bacteria: M. bovis, M. africanum, M. canetti and M. microti. (NCI) UMLS:C1032649 Mycobacterium complex NCBITAXON_US:77643 Mycobacterium tuberculosis complex NCBITAXON: 2020/02/11 NCBITAXON_US:77643 UMLS:C0010240 Rickettsia burneti Rickettsia diaporica NCBITAXON:777 Coxiella burnetii NCBITAXON: 2020/02/11 NCBITAXON:777 UMLS:C1034478 Burkholderia/Oxalobacter/Ralstonia group NCBITAXON:80840 Burkholderiales NCBITAXON: 2020/02/11 NCBITAXON:80840 UMLS:C0008152 NCBITAXON:809 Chlamydiaceae NCBITAXON: 2020/02/11 NCBITAXON:809 UMLS:C0008148 Bedsonia Chlamydophila Miyagawanella Rakeia Rickettsiaformis NCBITAXON:810 Chlamydia NCBITAXON: 2020/02/11 NCBITAXON:810 UMLS:C0315212 NCBITAXON:82976 Buttiauxella NCBITAXON: 2020/02/11 NCBITAXON:82976 UMLS:C0315213 NCBITAXON:82977 Buttiauxella agrestis NCBITAXON: 2020/02/11 NCBITAXON:82977 UMLS:C1035772 NCBITAXON:82988 Buttiauxella brennerae NCBITAXON: 2020/02/11 NCBITAXON:82988 UMLS:C1035773 NCBITAXON:82989 Buttiauxella ferragutiae NCBITAXON: 2020/02/11 NCBITAXON:82989 UMLS:C1035774 NCBITAXON:82990 Buttiauxella gaviniae NCBITAXON: 2020/02/11 NCBITAXON:82990 UMLS:C1035775 NCBITAXON:82991 Buttiauxella izardii NCBITAXON: 2020/02/11 NCBITAXON:82991 UMLS:C1035776 NCBITAXON:82992 Buttiauxella noackiae NCBITAXON: 2020/02/11 NCBITAXON:82992 UMLS:C1035777 NCBITAXON:82993 Buttiauxella warmboldiae NCBITAXON: 2020/02/11 NCBITAXON:82993 A genus of CHLAMYDOPHILA infecting primarily birds. It contains eight known serovars, some of which infect more than one type of host, including humans. (MSH) A species of gram negative, obligately intracellular, spherical shaped bacteria belonging to the phylum Chlamydiae. This species survives outside of its host as an elementary body. C. psittaci is pathogenic, being the causative agent of endemic avian chlamydiosis and epizootic infection in mammals. (NCI) Any bacterial organism that can be assigned to the species Chlamydophila psittaci. (NCI) Bacteria in the genus of Chlamydophila infecting primarily birds; contains eight known serovars, some of which infect more than one type of host, including humans. (CSP) UMLS:C0008150 Chlamydozoon psittaci Ehrlichia psittaci Rickettsia psittaci Rickettsiaformis psittacosis NCBITAXON:83554 Chlamydophila psittaci NCBITAXON: 2020/02/11 NCBITAXON:83554 SNOMEDCT_US:103514009 UMLS:C0085504 Chlamydophila pneumoniae NCBITAXON:83558 Chlamydia pneumoniae NCBITAXON: 2020/02/11 NCBITAXON:83558 UMLS:C0315273 NCBITAXON:83654 Leclercia NCBITAXON: 2020/02/11 NCBITAXON:83654 UMLS:C1037106 Corynebacterineae NCBITAXON:85007 Corynebacteriales NCBITAXON: 2020/02/11 NCBITAXON:85007 UMLS:C3055768 NCBITAXON:862793 Candidatus cuticobacterium NCBITAXON: 2020/02/11 NCBITAXON:862793 UMLS:C1038168 NCBITAXON:86661 Bacillus cereus group NCBITAXON: 2020/02/11 NCBITAXON:86661 Staphylococcus group NCBITAXON:90964 Staphylococcaceae NCBITAXON: 2020/02/11 NCBITAXON:90964 UMLS:C1040746 Bacillus/Lactobacillus/Streptococcus group Firmibacteria NCBITAXON:91061 Bacilli NCBITAXON: 2020/02/11 NCBITAXON:91061 UMLS:C1040967 Enterobacteriaceae and related endosymbionts Enterobacteriaceae group Enterobacteriales NCBITAXON:91347 Enterobacterales NCBITAXON: 2020/02/11 NCBITAXON:91347 UMLS:C1041134 Chlamydophila cf. pneumoniae CPXT1 NCBITAXON:91614 related_name: Chlamydophila cf. pneumoniae CPXT1 Chlamydia cf. pneumoniae CPXT1 NCBITAXON: 2020/02/11 NCBITAXON:91614 UMLS:C3099077 NCBITAXON:929812 Gibbsiella NCBITAXON: 2020/02/11 NCBITAXON:929812 UMLS:C0232289 Radiating chest pain (finding) SNOMEDCT_US:10000006 Radiating chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10000006 UMLS:C4039254 Chronic pneumonia (disorder) SNOMEDCT_US:102361000119104 Chronic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102361000119104 UMLS:C0522046 Cough suppression (finding) SNOMEDCT_US:102580004 Cough suppression SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102580004 UMLS:C0522049 Unequal blood pressure in arms (finding) SNOMEDCT_US:102584008 Unequal blood pressure in arms SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102584008 UMLS:C0522051 Acute chest pain (finding) SNOMEDCT_US:102587001 Acute chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102587001 UMLS:C0008035 Chest wall pain (finding) SNOMEDCT_US:102588006 Chest wall pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102588006 UMLS:C0262384 Atypical chest pain (finding) SNOMEDCT_US:102589003 Atypical chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:102589003 UMLS:C4520326 Pneumonia caused by Enterococcus (disorder) Pneumonia due to Enterococcus SNOMEDCT_US:10291000175108 Pneumonia caused by Enterococcus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10291000175108 UMLS:C4520337 Pneumonia caused by Serratia (disorder) Pneumonia due to Serratia SNOMEDCT_US:10301000175109 Pneumonia caused by Serratia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10301000175109 UMLS:C0522256 Thoracic nerve root pain (finding) SNOMEDCT_US:103015000 Thoracic nerve root pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103015000 UMLS:C4520338 Pneumonia caused by Enterobacter (disorder) Pneumonia due to Enterobacter SNOMEDCT_US:10311000175107 Pneumonia caused by Enterobacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10311000175107 UMLS:C0445881 Legionella pneumophila subsp fraseri SNOMEDCT_US:103456005 Legionella pneumophila ss. fraseri SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103456005 UMLS:C0445882 Legionella pneumophila subsp pascullei SNOMEDCT_US:103457001 Legionella pneumophila ss. pascullei SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103457001 UMLS:C0445883 Legionella pneumophila ss. pneumophila (organism) Legionella pneumophila subsp pneumophila SNOMEDCT_US:103457001 Legionella pneumophila ss. pneumophila SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103457001 UMLS:C0522384 Legionella pneumophila serogroup 1 (organism) SNOMEDCT_US:103463005 Legionella pneumophila serogroup 1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103463005 UMLS:C0522385 Legionella pneumophila serogroup 2 (organism) SNOMEDCT_US:103464004 Legionella pneumophila serogroup 2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103464004 UMLS:C0522386 Legionella pneumophila serogroup 3 (organism) SNOMEDCT_US:103465003 Legionella pneumophila serogroup 3 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103465003 UMLS:C0522387 Legionella pneumophila serogroup 4 (organism) SNOMEDCT_US:103466002 Legionella pneumophila serogroup 4 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103466002 UMLS:C0522388 Legionella pneumophila serogroup 5 (organism) SNOMEDCT_US:103467006 Legionella pneumophila serogroup 5 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103467006 UMLS:C0522389 Legionella pneumophila serogroup 6 (organism) SNOMEDCT_US:103468001 Legionella pneumophila serogroup 6 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103468001 UMLS:C0522390 Legionella pneumophila serogroup 7 (organism) SNOMEDCT_US:103469009 Legionella pneumophila serogroup 7 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103469009 UMLS:C0522391 Legionella pneumophila serogroup 8 (organism) SNOMEDCT_US:103470005 Legionella pneumophila serogroup 8 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103470005 UMLS:C0522392 Legionella pneumophila serogroup 9 (organism) SNOMEDCT_US:103471009 Legionella pneumophila serogroup 9 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:103471009 UMLS:C1142077 SNOMEDCT_US:104041000119108 Fungal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:104041000119108 UMLS:C0523806 Oxygen measurement (procedure) SNOMEDCT_US:104846005 Oxygen measurement SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:104846005 UMLS:C0264376 Non-infectious pneumonia (disorder) Non-infective pneumonitis Pneumonia of non-infectious cause Pneumonitis of non-infectious cause SNOMEDCT_US:105977003 Non-infectious pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:105977003 UMLS:C4038910 Bronchopneumonia caused by Achromobacter Bronchopneumonia caused by Achromobacter (disorder) SNOMEDCT_US:10624991000119103 Bronchopneumonia due to Achromobacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10624991000119103 UMLS:C4040720 Bronchopneumonia caused by anaerobic bacteria Bronchopneumonia caused by anaerobic bacteria (disorder) SNOMEDCT_US:10625031000119102 Bronchopneumonia due to anaerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625031000119102 UMLS:C4039717 Bronchopneumonia caused by bacteria Bronchopneumonia caused by bacteria (disorder) SNOMEDCT_US:10625071000119104 Bronchopneumonia due to bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625071000119104 UMLS:C4039892 Bronchopneumonia caused by Escherichia coli Bronchopneumonia caused by Escherichia coli (disorder) SNOMEDCT_US:10625111000119106 Bronchopneumonia due to Escherichia coli SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625111000119106 UMLS:C4040491 Bronchopneumonia caused by Haemophilus influenzae Bronchopneumonia caused by Haemophilus influenzae (disorder) SNOMEDCT_US:10625231000119106 Bronchopneumonia due to Haemophilus influenzae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625231000119106 UMLS:C4039812 Bronchopneumonia caused by Human metapneumovirus Bronchopneumonia caused by Human metapneumovirus (disorder) SNOMEDCT_US:10625271000119109 Bronchopneumonia due to Human metapneumovirus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625271000119109 UMLS:C4041068 Bronchopneumonia caused by Klebsiella pneumoniae Bronchopneumonia caused by Klebsiella pneumoniae (disorder) SNOMEDCT_US:10625311000119109 Bronchopneumonia due to Klebsiella pneumoniae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625311000119109 UMLS:C4041093 Bronchopneumonia caused by methicillin resistant Staphylococcus aureus Bronchopneumonia caused by methicillin resistant Staphylococcus aureus (disorder) SNOMEDCT_US:10625351000119105 Bronchopneumonia due to methicillin resistant Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625351000119105 UMLS:C4040147 Bronchopneumonia caused by methicillin susceptible Staphylococcus aureus Bronchopneumonia caused by methicillin susceptible Staphylococcus aureus (disorder) SNOMEDCT_US:10625391000119100 Bronchopneumonia due to methicillin susceptible Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625391000119100 UMLS:C4038740 Bronchopneumonia caused by Mycoplasma pneumoniae Bronchopneumonia caused by Mycoplasma pneumoniae (disorder) SNOMEDCT_US:10625431000119105 Bronchopneumonia due to Mycoplasma pneumoniae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625431000119105 UMLS:C4038740 Bronchopneumonia caused by Proteus mirabilis Bronchopneumonia caused by Proteus mirabilis (disorder) SNOMEDCT_US:10625471000119108 Bronchopneumonia due to Proteus mirabilis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625471000119108 UMLS:C4038740 Bronchopneumonia caused by Pseudomonas Bronchopneumonia caused by Pseudomonas (disorder) SNOMEDCT_US:10625511000119104 Bronchopneumonia due to Pseudomonas SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625511000119104 UMLS:C4040464 Bronchopneumonia caused by respiratory syncytial virus Bronchopneumonia caused by respiratory syncytial virus (disorder) SNOMEDCT_US:10625551000119103 Bronchopneumonia due to respiratory syncytial virus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625551000119103 UMLS:C4041440 Bronchopneumonia caused by Staphylococcus Bronchopneumonia caused by Staphylococcus (disorder) SNOMEDCT_US:10625591000119108 Bronchopneumonia due to Staphylococcus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625591000119108 UMLS:C4039451 Bronchopneumonia caused by Staphylococcus aureus Bronchopneumonia caused by Staphylococcus aureus (disorder) SNOMEDCT_US:10625631000119108 Bronchopneumonia due to Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625631000119108 UMLS:C4040383 Bronchopneumonia caused by Streptococcus Bronchopneumonia caused by Streptococcus (disorder) SNOMEDCT_US:10625671000119106 Bronchopneumonia due to Streptococcus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625671000119106 UMLS:C4040397 Bronchopneumonia due to virus (disorder) SNOMEDCT_US:10625751000119106 Bronchopneumonia due to virus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10625751000119106 UMLS:C3873581 Allergic rhinitis caused by mold (disorder) Allergic rhinitis caused by mould SNOMEDCT_US:10629471000119106 Allergic rhinitis caused by mold SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10629471000119106 UMLS:C4039649 SNOMEDCT_US:10629511000119102 Rhinitis of pregnancy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10629511000119102 Hypoxaemic respiratory failure Hypoxemic respiratory failure (disorder) SNOMEDCT_US:10676831000119101 Hypoxemic respiratory failure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10676831000119101 UMLS:C3853540 Samter triad SNOMEDCT_US:10692681000119108 Aspirin exacerbated respiratory disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10692681000119108 UMLS:C3840016 Pneumonia caused by Ascaris Pneumonia caused by Ascaris (disorder) SNOMEDCT_US:1082721000119101 Pneumonia due to Ascaris SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1082721000119101 A procedure that uses a bronchoscope to examine the inside of the trachea, bronchi (air passages that lead to the lungs), and lungs. A bronchoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue to be checked under a microscope for signs of disease. The bronchoscope is inserted through the nose or mouth. Bronchoscopy may be used to detect cancer or to perform some treatment procedures. (NCI) UMLS:C0006290 Bronchial endoscopy Bronchoscopy (procedure) By - Bronchoscopy Endoscopy of bronchus Tracheobronchial endoscopy SNOMEDCT_US:10847001 Bronchoscopy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:10847001 UMLS:C3839882 Meningitis caused by Sporothrix schenkii Meningitis caused by Sporothrix schenkii (disorder) SNOMEDCT_US:1084801000119107 Meningitis due to Sporothrix schenkii SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1084801000119107 UMLS:C4040157 Meningitis due to Cytomegaloviral Mononucleosis (disorder) SNOMEDCT_US:1085361000119104 Meningitis due to Cytomegaloviral Mononucleosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1085361000119104 UMLS:C2893395 Gonococcal pneumonia (disorder) SNOMEDCT_US:1087061000119106 Gonococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1087061000119106 UMLS:C4041356 Meningitis due to Chagas disease (disorder) SNOMEDCT_US:1089781000119109 Meningitis due to Chagas disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1089781000119109 UMLS:C4039274 Meningitis due to infectious mononucleosis (disorder) SNOMEDCT_US:1089791000119107 Meningitis due to infectious mononucleosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1089791000119107 UMLS:C2900504 Meningitis caused by Rubella virus (disorder) Rubella meningitis Rubella virus meningitis SNOMEDCT_US:1092351000119107 Meningitis caused by Rubella virus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1092351000119107 UMLS:C2911579 Rubella pneumonia (disorder) SNOMEDCT_US:1092361000119109 Rubella pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:1092361000119109 UMLS:C1263849 Acute purulent meningitis (disorder) SNOMEDCT_US:109902004 Acute purulent meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:109902004 UMLS:C4511590 Cannabis hyperemesis syndrome co-occurrent and due to cannabis dependence (disorder) SNOMEDCT_US:11047881000119101 Cannabis hyperemesis syndrome co-occurrent and due to cannabis abuse SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11047881000119101 UMLS:C4511594 Cannabis hyperemesis syndrome co-occurrent and due to cannabis abuse (disorder) SNOMEDCT_US:11048011000119103 Cannabis hyperemesis syndrome co-occurrent and due to cannabis dependence SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11048011000119103 UMLS:C4551354 Cyanosis of skin and/or skin-associated mucous membrane (finding) SNOMEDCT_US:111000161106 Cyanosis of skin and/or skin-associated mucous membrane SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:111000161106 UMLS:C0264228 Acute abscess of nasal sinus (disorder) SNOMEDCT:111274000 Acute abscess of nasal sinus SNOMEDCT_US: 2021/01/06 SNOMEDCT:111274000 UMLS:C0024228 Disorder of lymphoid system (disorder) SNOMEDCT_US:111590001 Disorder of lymphoid system SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:111590001 UMLS:C0155867 Aspergillus pneumonia Pneumonia in aspergillosis (disorder) Pneumonia with aspergillosis SNOMEDCT_US:111900000 Pneumonia in aspergillosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:111900000 UMLS:C0231917 Postural cough (finding) SNOMEDCT_US:111962006 Postural cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:111962006 UMLS:C0232114 Abnormal venous pressure (finding) SNOMEDCT_US:111971002 Abnormal venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:111971002 UMLS:C0035591 Family Rickettsiaceae Family Rickettsiaceae (organism) SNOMEDCT_US:115081009 Rickettsiaceae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115081009 UMLS:C0008544 Family Chromatiaceae Family Chromatiaceae (organism) SNOMEDCT_US:115101008 Chromatiaceae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115101008 UMLS:C2828040 Gram-negative aerobic bacillus Gram-negative aerobic rod (organism) SNOMEDCT_US:115172000 Gram-negative aerobic rod SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115172000 UMLS:C0315020 Brachyspira species Genus Brachyspira Genus Brachyspira (organism) SNOMEDCT_US:11572003 Brachyspira SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11572003 UMLS:C0275907 Tuberculous leptomeningitis (disorder) SNOMEDCT_US:11676005 Tuberculous leptomeningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11676005 UMLS:C0267525 Bilious vomiting following gastrointestinal surgery (disorder) SNOMEDCT_US:11767005 Bilious vomiting following gastrointestinal surgery SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11767005 A cough that does not produce phlegm or mucus. (HPO) UMLS:C0850149 Dry cough (finding) Dry coughing Non-productive cough Unproductive cough SNOMEDCT_US:11833005 Dry cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:11833005 UMLS:C0872391 SNOMEDCT_US:118792002 Procedure on trachea SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:118792002 UMLS:C0154640 Staphylococcal meningitis (disorder) SNOMEDCT_US:12166008 Staphylococcal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:12166008 UMLS:C1290336 Acute bronchopneumonia (disorder) SNOMEDCT_US:123587001 Acute bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123587001 UMLS:C1290337 Confluent bronchopneumonia with abscess formation (disorder) SNOMEDCT_US:123588006 Confluent bronchopneumonia with abscess formation SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123588006 UMLS:C1290338 Necrotising bronchopneumonia Necrotizing bronchopneumonia (disorder) SNOMEDCT_US:123589003 Necrotizing bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123589003 UMLS:C1290339 Focal pneumonia (disorder) SNOMEDCT_US:123590007 Focal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123590007 UMLS:C1290340 Confluent pneumonia (disorder) SNOMEDCT_US:123591006 Confluent pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123591006 UMLS:C0277896 Increased central venous pressure (finding) SNOMEDCT_US:12377007 Increased central venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:12377007 UMLS:C0425500 Cough reflex absent (finding) SNOMEDCT_US:123819004 Cough reflex absent SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:123819004 MRSA PNA MRSA pneumonia Pneumonia caused by methicillin resistant Staphylococcus aureus (disorder) Pneumonia caused by methicillin resistant staphylococcus aureus SNOMEDCT_US:124691000119101 Pneumonia due to methicillin resistant Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:124691000119101 UMLS:C0577962 Expiratory crackles (finding) SNOMEDCT_US:12529006 Expiratory crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:12529006 UMLS:C1257958 Disorder of glucose metabolism (disorder) SNOMEDCT_US:126877002 Disorder of glucose metabolism SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:126877002 A finding of decreased blood pressure; not necessarily hypotensive disorder. (SNOMEDCT_US) UMLS:C0232107 Finding of decreased blood pressure SNOMEDCT_US:12763006 Decreased blood pressure, not hypotension SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:12763006 An infectious or non infectious disorder characterized by signs and symptoms derived from focal or extensive tissue infiltration by acute (e.g., polymorphonuclear) or chronic (e.g., lymphocytic-plasmacytic) inflammatory cells. Representative examples of infectious disorders include viral infections, bacterial infections, and parasitic infections. Representative examples of non-infectious inflammatory disorders include inflammatory bowel disease and inflammatory polyps. (NCI) UMLS:C1290884 Inflammatory disease Inflammatory disorder (disorder) SNOMEDCT_US:128139000 Inflammatory disorder SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:128139000 UMLS:C2349529 MSSA PNA MSSA pneumonia Pneumonia caused by methicillin susceptible staphylococcus aureus SNOMEDCT_US:128711000119106 Pneumonia due to methicillin susceptible Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:128711000119106 UMLS:C1535528 Aspiration from trachea (procedure) Tracheal suction SNOMEDCT_US:129112001 Aspiration from trachea SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:129112001 Change in or modification of the systolic or diastolic pressure. (CCC) UMLS:C1268766 SNOMEDCT_US:129899009 Blood pressure alteration SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:129899009 UMLS:C4038630 Cellulitis of nasal mucous membrane SNOMEDCT_US:130021000119100 Cellulitis of nasal mucous membrane SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:130021000119100 UMLS:C0232291 Pleuropericardial chest pain (finding) SNOMEDCT_US:13057000 Pleuropericardial chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:13057000 UMLS:C1295846 Legionella pneumophila serogroup 10 (organism) SNOMEDCT_US:131322009 Legionella pneumophila serogroup 10 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131322009 UMLS:C1295847 Legionella pneumophila serogroup 11 (organism) SNOMEDCT_US:131323004 Legionella pneumophila serogroup 11 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131323004 UMLS:C1295848 Legionella pneumophila serogroup 12 (organism) SNOMEDCT_US:131324005 Legionella pneumophila serogroup 12 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131324005 UMLS:C1295849 Legionella pneumophila serogroup 13 (organism) SNOMEDCT_US:131325006 Legionella pneumophila serogroup 13 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131325006 UMLS:C1295850 Legionella pneumophila serogroup 14 (organism) SNOMEDCT_US:131326007 Legionella pneumophila serogroup 14 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131326007 UMLS:C4039039 Arbovirus meningitis SNOMEDCT_US:131411000119107 Meningitis caused by arbovirus infection SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:131411000119107 Inflammation of the NASAL MUCOSA in the SPHENOID SINUS. Isolated sphenoid sinusitis is uncommon. It usually occurs in conjunction with other paranasal sinusitis. (MSH) UMLS:C0037886 SNOMEDCT_US:13266007 Sphenoidal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:13266007 UMLS:C3874311 Vomiting faecal matter Vomiting faecal matter (disorder) SNOMEDCT_US:134021000119105 Vomiting fecal matter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:134021000119105 A sign or symptom of weakness and diminished or absent energy and strength. (NCI) Asthenia or weakness is a lack of energy manifested as generalized lack of physical or muscle strength. Asthenia is not necessarily relieved by rest. (SNOMEDCT_US) HP:0025406 UMLS:C0004093 Asthenia (finding) Debility Feeling weak General weakness Lassitude Weakness Weakness - general SNOMEDCT_US:13791008 Asthenia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:13791008 UMLS:C0020450 Hyperemesis arising during pregnancy Excessive pregnancy vomiting Excessive vomiting in pregnancy Excessive vomiting in pregnancy (disorder) Hyperemesis arising during pregnancy Hyperemesis in pregnancy Hyperemesis of pregnancy Persistent AND/OR vicious vomiting arising during pregnancy SNOMEDCT_US:14094001 Hyperemesis gravidarum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:14094001 UMLS:C2910398 Vomiting without nausea (disorder) SNOMEDCT_US:146291000119108 Vomiting without nausea SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:146291000119108 UMLS:C0153225 meningitis due to gonococcus SNOMEDCT_US:151004 Gonococcal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:151004 The use of alcoholic beverages to excess, either on individual occasions ("binge drinking") or as a regular practice. (NCI) UMLS:C0085762 AA - Alcohol abuse Alcohol abuse (disorder) Ethanol abuse SNOMEDCT_US:15167005 Alcohol abuse SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:15167005 UMLS:C3266211 Influenza A virus subtype H1 swine-like (organism) SNOMEDCT_US:161000124103 Influenza A virus subtype H1 swine-like SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161000124103 UMLS:C0581912 Heaviness sensation Heavy feeling (finding) SNOMEDCT_US:161874006 Heavy feeling SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161874006 A sudden movement downward, usually resulting in injury. (NCI) LNC:LA17133-2 UMLS:C0085639 Falls (finding) SNOMEDCT_US:161898004 Falls SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161898004 UMLS:C0425505 Productive cough -clear sputum (finding) coughing up clear sputum SNOMEDCT_US:161923004 Productive cough -clear sputum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161923004 UMLS:C0425504 Productive cough -green sputum (finding) SNOMEDCT_US:161924005 Productive cough -green sputum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161924005 UMLS:C0425506 Productive cough-yellow sputum (finding) SNOMEDCT_US:161925006 Productive cough-yellow sputum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161925006 UMLS:C0240351 Morning cough (finding) SNOMEDCT_US:161932002 Morning cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161932002 UMLS:C0581864 Evening cough (finding) SNOMEDCT_US:161933007 Evening cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161933007 UMLS:C0438985 Nocturnal cough / wheeze (finding) SNOMEDCT_US:161947006 Nocturnal cough / wheeze SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161947006 UMLS:C0423634 Central chest pain (finding) SNOMEDCT_US:161972006 Central chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161972006 UMLS:C0423633 Parasternal pain (finding) SNOMEDCT_US:161974007 Parasternal pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:161974007 UMLS:C0581881 Heavy head (finding) SNOMEDCT_US:162311003 Heavy head SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:162311003 UMLS:C0240194 Blue lips (finding) SNOMEDCT_US:162743000 Blue lips SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:162743000 Failure of a physiologic function or system. (NCI) UMLS:C0332521 Collapse (morphologic abnormality) SNOMEDCT_US:16277007 Collapse SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:16277007 UMLS:C0436747 O/E - crackles On examination - coarse crepitations On examination - coarse crepitations (finding)) SNOMEDCT_US:162965007 O/E - coarse crepitations SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:162965007 UMLS:C0436748 On examination - fine crepitations On examination - fine crepitations (finding) SNOMEDCT_US:162966008 O/E - fine crepitations SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:162966008 UMLS:C0436781 O/E - BP reading O/E - blood pressure On examination - blood pressure reading On examination - blood pressure reading (finding) SNOMEDCT_US:163020007 O/E - blood pressure reading SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:163020007 UMLS:C4038890 Pneumonia caused by influenza Pneumonia caused by influenza (disorder) SNOMEDCT_US:16311000119108 Pneumonia due to influenza SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:16311000119108 UMLS:C0437245 On examination - febrile convulsion On examination - febrile convulsion (finding) SNOMEDCT:163595003 O/E - febrile convulsion SNOMEDCT_US: 2021/01/06 SNOMEDCT:163595003 UMLS:C0437736 O/E - hypothermia - less than 32 degrees Celsius SNOMEDCT_US: 164302002 On examination - hypothermia - less than 32 degrees Celsius SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 164302002 UMLS:C0428876 Intracardiac pressure (observable entity) SNOMEDCT_US:165077006 Intracardiac pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:165077006 C0430359 SNOMEDCT_US:167944006 Pleural fluid examination SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:167944006 UMLS:C0027498 N&V - Nausea and vomiting N+V - Nausea and vomiting Nausea and vomiting (disorder) SNOMEDCT_US:16932000 Nausea and vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:16932000 UMLS:C0396472 Endoscopic aspiration of trachea using rigid bronchoscope (procedure) SNOMEDCT_US:173085000 Endoscopic aspiration of trachea using rigid bronchoscope SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:173085000 UMLS:C0472556 Fiberoptic endoscopic aspiration of trachea (procedure) SNOMEDC_US:173141004 Fiberoptic endoscopic aspiration of trachea SNOMEDCT_US: 2021/01/06 SNOMEDC_US:173141004 UMLS:C0022731 Klebsiella pneumoniae subsp rhinoscleromatis SNOMEDCT_US:17688001 Klebsiella pneumoniae ss. rhinoscleromatis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:17688001 UMLS:C0318200 Genus Succinimonas Genus Succinimonas (organism) Succinimonas species SNOMEDCT_US:17726008 Succinimona SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:17726008 UMLS:C0085315 Acquired toxoplasmal meningoencephalitis Meningoencephalitis due to acquired toxoplasmosis (disorder) SNOMEDCT_US:17949000 Meningoencephalitis due to acquired toxoplasmosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:17949000 UMLS:C0234866 Barking cough (finding) SNOMEDCT_US:17986004 Barking cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:17986004 UMLS:C0264378 Haemorrhagic bronchopneumonia Hemorrhagic bronchopneumonia (disorder) SNOMEDCT_US:181007 Hemorrhagic bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:181007 UMLS:C0318341 Chlamydia psittaci var. ovis Chlamydophila psittaci var. ovis Chlamydophila psittaci variant ovis (organism) SNOMEDCT_US:18279000 Chlamydophila psittaci variant ovis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:18279000 UMLS:C0520703 SNOMEDCT_US:18311006 Aseptic meningitis due to drug SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:18311006 UMLS:C0277883 Abnormal systolic arterial pressure (finding) Abnormal systolic blood pressure SNOMEDCT_US:18352002 Abnormal systolic arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:18352002 UMLS:C0315264 Klebsiella pneumoniae subsp pneumoniae SNOMEDCT_US:18400002 Klebsiella pneumoniae ss. pneumoniae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:18400002 UMLS:C0524687 Plague meningitis (disorder) SNOMEDCT_US:186284005 Plague meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:186284005 Inflammation of the NASAL MUCOSA in the ETHMOID SINUS. It may present itself as an acute (infectious) or chronic (allergic) condition. (MSH) UMLS:C0015029 SNOMEDCT:18643000 Ethmoidal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT:18643000 UMLS:C0851315 Acute secondary syphilitic meningitis (disorder) SNOMEDCT_US:186863009 Acute secondary syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:186863009 UMLS:C0153232 Leptospiral meningitis (disorder) SNOMEDCT_US:186956008 Leptospiral meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:186956008 UMLS:C0153275 Pulmonary African histoplasmosis (disorder) SNOMEDCT_US:187052004 Pulmonary African histoplasmosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:187052004 UMLS:C0152164 Cyclical vomiting Cyclical vomiting syndrome (disorder) Periodic vomiting SNOMEDCT_US:18773000 Cyclical vomiting syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:18773000 A common hereditary disease in which exocrine (secretory) glands produce abnormally thick mucus. This mucus can cause problems in digestion, breathing, and body cooling. (NCI) UMLS:C0010674 CF CF - Cystic fibrosis Cystic fibrosis (disorder) Fibrocystic disease Mucoviscidosis SNOMEDCT_US:190905008 Cystic fibrosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:190905008 Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug. (NCI) UMLS:C1510472 Drug dependence (disorder) SNOMEDCT_US:191816009 Drug dependence SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:191816009 UMLS:C0025292 SNOMEDCT_US:192643004 Haemophilus meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192643004 UMLS:C0007813 UMLS:C0025294 Cerebrospinal meningitis Epidemic meningitis Meningococcal cerebrospinal fever SNOMEDCT_US:192644005 Meningococcal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192644005 UMLS:C0338399 Meningitis due to secondary syphilis SNOMEDCT_US:192647003 Secondary syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192647003 UMLS:C0338393 Actinomycotic meningitis (disorder) Meningitis due to actinomycosis SNOMEDCT_US:192649000 Actinomycotic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192649000 UMLS:C0393429 Meningitis caused by pertussis Meningitis caused by pertussis (disorder) SNOMEDCT_US:192650000 Meningitis due to pertussis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192650000 A form of gram-negative meningitis that tends to occur in neonates, in association with anatomical abnormalities (which feature communication between the meninges and cutaneous structures) or as OPPORTUNISTIC INFECTIONS in association with IMMUNOLOGIC DEFICIENCY SYNDROMES. In premature neonates the clinical presentation may be limited to ANOREXIA; VOMITING; lethargy; or respiratory distress. Full-term infants may have as additional features FEVER; SEIZURES; and bulging of the anterior fontanelle. (MSH) UMLS:C0338395 Meningitis due to Escherichia coli SNOMEDCT_US:192655005 Escherichia coli meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192655005 UMLS:C0589627 Meningitis due to proteus morganii SNOMEDCT_US:192659004 Morganella morganii meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192659004 UMLS:C0154651 Meningitis with clear cerebrospinal fluid Non-pyogenic meningitis (disorder) SNOMEDCT_US:192679007 Non-pyogenic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:192679007 UMLS:C0586750 Cough on exercise (finding) SNOMEDCT_US:19282004 Cough on exercise SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:19282004 The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION. (MSH) UMLS:C0002962 AP - Angina pectoris Angina Angina (disorder) Anginal syndrome Cardiac angina Ischaemic heart disease - angina Ischemic heart disease - angina Stenocardia SNOMEDCT_US:194828000 Angina pectoris SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:194828000 UMLS:C0339799 Chronic hypertrophic rhinitis (disorder) SNOMEDCT_US:195768000 Chronic hypertrophic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195768000 UMLS:C3241963 Chronic atrophic rhinitis syndrome SNOMEDCT_US:195769008 Chronic atrophic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195769008 UMLS:C0339798 Chronic infective rhinitis (disorder) SNOMEDCT_US:195770009 Chronic infective rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195770009 UMLS:C0339801 UMLS:C0684902 Chronic ulcerative rhinitis (disorder) SNOMEDCT_US:195771008 Chronic ulcerative rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195771008 UMLS:C0339795 Chronic membranous rhinitis (disorder) SNOMEDCT_US:195772001 Chronic membranous rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195772001 UMLS:C0339796 Chronic fibrinous rhinitis (disorder) SNOMEDCT_US:195773006 Chronic fibrinous rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195773006 UMLS:C0558362 SNOMEDCT_US:195790000 Pansinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195790000 UMLS:C0152413 Pneumonia caused by respiratory syncytial virus Pneumonia caused by respiratory syncytial virus (disorder) SNOMEDCT_US:195881003 Pneumonia due to respiratory syncytial virus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195881003 UMLS:C0348801 Group B streptococcal pneumonia (disorder) SNOMEDCT_US:195886008 Group B streptococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195886008 UMLS:C1260917 Proteus pneumonia (disorder) SNOMEDCT_US:195888009 Proteus pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195888009 UMLS:C0023241 Legionella pneumonia (disorder) Legionnaire's disease Legionnaires disease Legionnaires' disease SNOMEDCT_US:195889001 Legionella pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195889001 UMLS:C0553970 Pneumonia caused by pleuropneumonia-like organism Pneumonia caused by pleuropneumonia-like organism (disorder) SNOMEDCT_US:195896004 Pneumonia due to pleuropneumonia-like organism SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195896004 UMLS:C0339976 Pneumonia co-occurrent and due to measles Pneumonia co-occurrent and due to measles (disorder) SNOMEDCT_US:195900001 Measles pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195900001 UMLS:C0023241 Anthrax pneumonia (disorder) Pneumonia with anthrax SNOMEDCT_US:195902009 Anthrax pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195902009 UMLS:C0553969 Pneumonia with coccidioidomycosis (disorder) SNOMEDCT_US:195904005 Pneumonia with coccidioidomycosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195904005 UMLS:C0339955 Actinomycotic pneumonia (disorder) SNOMEDCT_US:195908008 Actinomycotic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195908008 UMLS:C0339949 Nocardial pneumonia (disorder) Pneumonia with nocardiasis SNOMEDCT_US:195909000 Nocardial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195909000 UMLS:C0339971 Chicken pox pneumonia Chickenpox pneumonia (disorder) Varicella pneumonia Varicella pneumonitis SNOMEDCT_US:195911009 Chickenpox pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195911009 A chronic disease in which the bronchial airways in the lungs become narrowed and swollen, making it difficult to breathe. Symptoms include wheezing, coughing, tightness in the chest, shortness of breath, and rapid breathing. An attack may be brought on by pet hair, dust, smoke, pollen, mold, exercise, cold air, or stress. (NCI) UMLS:C0004096 Airway hyperreactivity Asthma (disorder) Asthmatic BHR - Bronchial hyperreactivity Bronchial asthma Bronchial hyperreactivity Bronchial hyperresponsiveness Bronchial hypersensitivity Hyperreactive airway disease SNOMEDCT_US:195967001 Asthma SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:195967001 UMLS:C0155908 Abscess of lung and mediastinum (disorder) SNOMEDCT_US:196107009 Abscess of lung and mediastinum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:196107009 UMLS:C0339978 Single lung abscess (disorder) SNOMEDCT_US:196108004 Single lung abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:196108004 UMLS:C0339979 Multiple lung abscesses (disorder) SNOMEDCT_US:196109007 Multiple lung abscesses SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:196109007 UMLS:C0348806 Abscess of lung with pneumonia (disorder) SNOMEDCT_US:196112005 Abscess of lung with pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:196112005 UMLS:C1368021 Pulmonary insufficiency following shock (disorder) SNOMEDCT:196151000 Pulmonary insufficiency following shock SNOMEDCT_US: 2021/01/06 SNOMEDCT:196151000 UMLS:C1368022 Pulmonary insufficiency following surgery (disorder) SNOMEDCT:196152007 Pulmonary insufficiency following surgery SNOMEDCT_US: 2021/01/06 SNOMEDCT:196152007 UMLS:C1368020 Pulmonary insufficiency following trauma (disorder) SNOMEDCT:196153002 Pulmonary insufficiency following trauma SNOMEDCT_US: 2021/01/06 SNOMEDCT:196153002 UMLS:C0152165 Emesis - persistent Persistent vomiting (disorder) SNOMEDCT_US:196746003 Persistent vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:196746003 UMLS:C0343320 Congenital staphylococcal pneumonia (disorder) SNOMEDCT_US:206283000 Congenital staphylococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206283000 UMLS:C0343321 Congenital group A haemolytic streptococcal pneumonia SNOMEDCT_US:206284006 Congenital group A hemolytic streptococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206284006 UMLS:C0495390 Congenital group B haemolytic streptococcal pneumonia SNOMEDCT_US:206285007 Congenital group B hemolytic streptococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206285007 UMLS:C0343323 SNOMEDCT_US:206286008 Congenital Escherichia coli pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206286008 UMLS:C0343324 Congenital pneumonia due to pseudomonas SNOMEDCT_US:206287004 Congenital pseudomonal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206287004 UMLS:C0349359 SNOMEDCT_US:206289001 Congenital chlamydial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206289001 UMLS:C0473792 Perinatal haematemesis Perinatal hematemesis (disorder) SNOMEDCT_US:206406008 Perinatal hematemesis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206406008 UMLS:C0475597 Neonatal haematemesis Neonatal hematemesis (disorder) SNOMEDCT_US:206423004 Neonatal hematemesis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:206423004 UMLS:C0277872 Brassy cough (finding) SNOMEDCT_US:20670007 Brassy cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:20670007 UMLS:C0149670 Disorder of carbohydrate metabolism (disorder) SNOMEDCT_US:20957000 Disorder of carbohydrate metabolism SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:20957000 UMLS:C0274285 Hypothermia - accidental (finding) SNOMEDCT_US: 212916004 Hypothermia - accidental SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 212916004 UMLS:C3266271 Influenza A virus subtype H1 2009 pandemic strain (organism) SNOMEDCT_US:221000124104 Influenza A virus subtype H1 2009 pandemic strain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:221000124104 Painful sensation in the pleura. (NCI) UMLS:C0008033 Painful breathing -pleurodynia Pleural pain Pleuralgia Pleuritic pain (finding) Pleurodynia SNOMEDCT_US:2237002 Pleuritic pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:2237002 UMLS:C0002962 Ischaemic chest pain SNOMEDCT_US:225566008 Ischemic chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:225566008 UMLS:C0558175 SNOMEDCT_US:225586007 Vomiting food SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:225586007 UMLS:C0455258 Endotracheal tube suction (procedure) SNOMEDCT_US:225715000 Endotracheal tube suction SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:225715000 UMLS:C0032308 Staphylococcal pneumonia (disorder) SNOMEDCT_US:22754005 Staphylococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:22754005 UMLS:C0393435 Staphylococcus aureus meningitis (disorder) SNOMEDCT_US:230148000 Staphylococcus aureus meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230148000 UMLS:C0393436 Staphylococcus epidermidis meningitis (disorder) SNOMEDCT_US:230149008 Staphylococcus epidermidis meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230149008 UMLS:C0338394 Meningitis in Lyme disease (disorder) SNOMEDCT_US:230150008 Meningitis in Lyme disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230150008 UMLS:C0338398 Late congenital syphilitic meningitis (disorder) SNOMEDCT_US:230152000 Late congenital syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230152000 UMLS:C0393439 Parasitic meningitis (disorder) SNOMEDCT_US:230153005 Parasitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230153005 Meningitis that persists for more than 4 weeks, and lymphocytes are present in the cerebrospinal fluid (CSF). (HPO) HP:0007041 UMLS:C0393441 SNOMEDCT_US:230154004 Chronic lymphocytic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230154004 UMLS:C0393491 Extradural supratentorial pyogenic abscess SNOMEDCT_US:230204001 Epidural supratentorial pyogenic abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230204001 UMLS:C0393494 Subdural supratentorial pyogenic abscess (disorder) SNOMEDCT_US:230206004 Subdural supratentorial pyogenic abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230206004 UMLS:C0393495 Subdural infratentorial pyogenic abscess (disorder) SNOMEDCT_US:230207008 Subdural infratentorial pyogenic abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230207008 UMLS:C0393708 Familial febrile convulsions (disorder) SNOMEDCT:230432008 Familial febrile convulsions SNOMEDCT_US: 2021/01/06 SNOMEDCT:230432008 UMLS:C0339802 nasal cholesteatoma Nasal cholesteatoma Rhinitis caseosa (disorder) SNOMEDCT_US:232344001 Rhinitis caseosa SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:232344001 UMLS:C0395982 SNOMEDCT_US:232390009 Suppurative sinusitis with complications SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:232390009 UMLS:C0396649 Orotracheal suction (procedure) Tracheal suction via mouth SNOMEDCT_US:232702005 Orotracheal suction SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:232702005 UMLS:C0396650 Tracheal suction via tracheostomy (procedure) SNOMEDCT_US:232703000 Tracheal suction via tracheostomy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:232703000 UMLS:C0155862 Pneumococcal pneumonia (disorder) SNOMEDCT_US:233607000 Pneumococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233607000 UMLS:C0339957 Meningococcal pneumonia (disorder) SNOMEDCT_US:233608005 Meningococcal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233608005 UMLS:C0339959 Chlamydial pneumonia Pneumonia caused by Chlamydiaceae SNOMEDCT_US:233609002 Pneumonia caused by Chlamydiaceae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233609002 UMLS:C0339960 Neonatal chlamydial lung infection Neonatal chlamydial pneumonia (disorder) Neonatal chlamydial pneumonitis SNOMEDCT_US:233610007 Neonatal chlamydial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233610007 UMLS:C0339961 Fungal pneumonia (disorder) SNOMEDCT_US:233613009 Fungal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233613009 UMLS:C0339962 Pulmonary mucormycosis (disorder) SNOMEDCT_US:233614003 Pulmonary mucormycosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233614003 UMLS:C0339965 Haemorrhagic pneumonia Hemorrhagic pneumonia (disorder) SNOMEDCT_US:233617005 Hemorrhagic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233617005 UMLS:C0339967 Mycobacterial pneumonia (disorder) SNOMEDCT_US:233618000 Mycobacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233618000 UMLS:C0339968 Neonatal pneumonia (disorder) SNOMEDCT_US:233619008 Neonatal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233619008 UMLS:C0339969 Pneumonia due to parasitic infestation (disorder) SNOMEDCT_US:233620002 Pneumonia due to parasitic infestation SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233620002 UMLS:C0032307 Pneumorickettsiosis Rickettsial pneumonia (disorder) SNOMEDCT_US:233621003 Rickettsial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233621003 UMLS:C0339973 Glandular fever pneumonia Infectious mononucleosis pneumonia (disorder) SNOMEDCT_US:233622005 Infectious mononucleosis pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233622005 UMLS:C0339974 Mononuclear interstitial pneumonia (disorder) SNOMEDCT_US:233623000 Mononuclear interstitial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233623000 UMLS:C0339975 Herpes simplex pneumonia (disorder) SNOMEDCT_US:233624006 Herpes simplex pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233624006 UMLS:C0153049 Giant cell pneumonia (disorder) SNOMEDCT_US:233625007 Giant cell pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233625007 UMLS:C0206062 Diffuse parenchymal lung disease ILD - Interstitial lung disease Interstitial lung disease (disorder) SNOMEDCT_US:233703007 Interstitial lung disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233703007 UMLS:C0340109 Seasonal cryptogenic organising pneumonia with biochemical cholestasis Seasonal cryptogenic organizing pneumonia with biochemical cholestasis (disorder) SNOMEDCT_US:233713004 Seasonal cryptogenic organizing pneumonia with biochemical cholestasis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233713004 UMLS:C0340142 Lupoid pneumonia Lupus pneumonia (disorder) SNOMEDCT_US:233730002 Lupus pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233730002 UMLS:C0340143 Contusion pneumonia Traumatic pneumonia (disorder) SNOMEDCT_US:233731003 Traumatic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233731003 An abnormal communication between a bronchus and the pleural cavity. (NCI) UMLS:C0238132 Bronchopleural fistula (disorder) SNOMEDCT_US:233793003 Bronchopleural fistula SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233793003 UMLS:C0340237 Tuberculous bronchopleural fistula (disorder) SNOMEDCT_US:233794009 Tuberculous bronchopleural fistula SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233794009 UMLS:C0206064 UMLS:C0856169 Cardiac syndrome X (finding) Chest pain with normal coronary angiography Coronary microvascular disease Coronary small artery disease Endothelial dysfunction Microvascular angina SNOMEDCT_US:233845001 Cardiac syndrome X SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233845001 UMLS:C0232116 Decreased venous pressure (finding) SNOMEDCT_US:23520002 Decreased venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:23520002 UMLS:C0401157 Intermittent vomiting (disorder) SNOMEDCT_US:236083006 Intermittent vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:236083006 An infectious or non infectious disorder characterized by signs and symptoms derived from focal or extensive tissue infiltration by acute (e.g., polymorphonuclear) or chronic (e.g., lymphocytic-plasmacytic) inflammatory cells. Representative examples of infectious disorders include viral infections, bacterial infections, and parasitic infections. Representative examples of non-infectious inflammatory disorders include inflammatory bowel disease and inflammatory polyps. (NCI) UMLS:C0242966 SIRS - System inflammatory response syndrome Systemic inflammatory response syndrome (disorder) SNOMEDCT_US:238149007 Systemic inflammatory response syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:238149007 UMLS:C0232597 Acute vomiting (disorder) SNOMEDCT_US:23971007 Acute vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:23971007 UMLS:C0413299 SNOMEDCT_US:242015007 Exhaustion - physiological SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:242015007 UMLS:C0038580 UMLS:C1510472 Dependence syndrome Psychoactive substance dependence (disorder) Substance dependence SNOMEDCT_US:2403008 Psychoactive substance dependence SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:2403008 UMLS:C0343436 Pulmonary glanders (disorder)) SNOMEDCT_US:240387006 Pulmonary glanders SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:240387006 UMLS:C0343440 Pulmonary melioidosis (disorder) SNOMEDCT_US:240391001 Pulmonary melioidosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:240391001 UMLS:C0343782 Pneumonia caused by Leishmania Pneumonia caused by Leishmania (disorder) SNOMEDCT_US:233620002 Leishmanial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:233620002 UMLS:C0343912 Acute pulmonary African histoplasmosis (disorder) SNOMEDCT_US:240741002 Acute pulmonary African histoplasmosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:240741002 UMLS:C0343913 Chronic pulmonary African histoplasmosis (disorder) SNOMEDCT_US:240742009 Chronic pulmonary African histoplasmosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:240742009 UMLS:C0343920 Chronic pulmonary blastomycosis SNOMEDCT_US:240747003 Chronic pulmonary blastomycosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:240747003 A finding of increased blood pressure; not necessarily hypertensive disorder. (SNOMEDCT_US) UMLS:C0497247 Blood pressure elevation Finding of increased blood pressure Finding of increased blood pressure (finding) Raised blood pressure SNOMEDCT_US:24184005 Elevated blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:24184005 UMLS:C0413251 Accidental hypothermia in elderly person (finding) SNOMEDCT_US: 241969009 Accidental hypothermia in elderly person SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 241969009 Meningitis caused by fungal agents which may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts. (MSH) UMLS:C0085438 Fungal meningitis (disorder) SNOMEDCT_US:24321005 Fungal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:24321005 UMLS:C0445733 LF - Lactose fermenter Lactose fermenter (organism) SNOMEDCT_US:243290004 Lactose fermenter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243290004 UMLS:C0445734 NLF - Non-lactose fermenter Non-lactose fermenter (organism) SNOMEDCT_US:243291000 Non-lactose fermenter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243291000 UMLS:C0445766 Non-Enterobacteriaceae (organism) SNOMEDCT_US:243311003 Non-Enterobacteriaceae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243311003 UMLS:C0445933 Anaerobic Gram-negative bacillus (organism) Anaerobic Gram-negative rod SNOMEDCT_US:243386003 Anaerobic Gram-negative bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243386003 UMLS:C0085476 Anaerobic Gram-negative coccus (organism) SNOMEDCT_US:243397003 Anaerobic Gram-negative coccus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243397003 UMLS:C0445954 Anaerobic Gram-positive bacillus (organism) Anaerobic Gram-positive rod SNOMEDCT_US:243398008 Anaerobic Gram-positive bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243398008 UMLS:C0445955 Anaerobic non-sporing Gram-positive bacillus (organism) Anaerobic non-sporing Gram-positive rod SNOMEDCT_US:243399000 Anaerobic non-sporing gram positive bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243399000 UMLS:C0445964 SNOMEDCT_US:243404003 Anaerobic spore-forming gram positive bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243404003 UMLS:C0445996 Anaerobic Gram-positive coccus (organism) SNOMEDCT_US:243416009 Anaerobic Gram-positive coccus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:243416009 UMLS:C0275683 Encephalitis in listeriosis SNOMEDCT_US:24630008 Listeria meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:24630008 UMLS:C0344306 Intercostal neuralgia (finding) SNOMEDCT_US:247389006 Intercostal neuralgia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:247389006 UMLS:C0423730 Painful cough SNOMEDCT_US:247410004 Painful cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:247410004 UMLS:C0424587 Easily exhausted Rapidly exhausted SNOMEDCT_US:248270006 Quickly exhausted SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248270006 UMLS:C0424588 SNOMEDCT_US:248271005 Exhausted on least exertion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248271005 UMLS:C0425496 Clearing throat - hawking (finding) SNOMEDCT_US:248589007 Clearing throat - hawking SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248589007 UMLS:C0425509 Cough when swallowing (finding) Coughs when swallowing SNOMEDCT_US:248593001 Cough when swallowing SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248593001 UMLS:C0425510 TOF - Tracheal esophageal fistula cough TOF - Tracheal esophageal fistula cough TOF - Tracheal oesophageal fistula cough Tracheal esophageal fistula cough (finding) Tracheal oesophageal fistula cough SNOMEDCT_US:248594007 Tracheal esophageal fistula cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248594007 UMLS:C0425545 Moist crackles (finding) Moist respiratory crepitations SNOMEDCT_US:248618001 Moist crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248618001 UMLS:C0425546 Bubbling crackles (finding)) SNOMEDCT_US:248619009 Bubbling crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:248619009 Interference with respiration by compression or obstruction of the larynx or trachea. (NCI) SNOMEDCT_US:249489001 Choking SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:249489001 Blood pressure in the pulmonary artery. (NCI) UMLS:C0428642 PA pressure - Pulmonary artery pressure PAP - Pulmonary artery pressure Pulmonary artery pressure (observable entity) SNOMEDCT_US:250767002 Pulmonary artery pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:250767002 The blood pressure in the pulmonary artery during the contraction of the left ventricle of the heart. (NCI) UMLS:C0428643 Pulmonary artery systolic pressure (observable entity) SNOMEDCT_US:250768007 Pulmonary artery systolic pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:250768007 The blood pressure in the pulmonary artery after the contraction of the heart while the chambers of the heart refill with blood. (NCI) UMLS:C0428644 PADP - Pulmonary artery diastolic pressure Pulmonary artery diastolic pressure (observable entity) SNOMEDCT_US:250769004 Pulmonary artery diastolic pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:250769004 UMLS:C0428678 total breath rate (observable entity) SNOMEDCT_US:250810003 Total breath rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:250810003 UMLS:C0450458 Ventricular pressure (observable entity) Ventricular pressure result SNOMEDCT_US:251069003 Ventricular pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:251069003 UMLS:C0152489 Salmonella pneumonia (disorder) SNOMEDCT_US:2523007 Salmonella pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:2523007 UMLS:C0555857 Bilious vomit on examination (disorder) SNOMEDCT_US:275744000 Bilious vomit on examination SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:275744000 Meningitis in which eosinophils predominate in the cerebrospinal fluid. (NCI) UMLS:C0154652 Eosinophilic meningitis (disorder) SNOMEDCT_US:25671008 Eosinophilic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:25671008 A method for amplifying a DNA base sequence using multiple rounds of heat denaturation of the DNA and annealing of oligonucleotide primers complementary to flanking regions in the presence of a heat-stable polymerase. This results in duplication of the targeted DNA region. Newly synthesized DNA strands can subsequently serve as additional templates for the same primer sequences, so that successive rounds of primer annealing, strand elongation, and dissociation produce rapid and highly specific amplification of the desired sequence. PCR also can be used to detect the existence of the defined sequence in a DNA sample. (NCI) PCR - Polymerase chain reaction SNOMEDCT_US:258066000 Polymerase chain reaction SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:258066000 UMLS:C0030167 Pachymeningitis (disorder) SNOMEDCT_US:25822001 Pachymeningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:25822001 UMLS:C2887055 SNOMEDCT_US:25957002 Aseptic leptospiral meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:25957002 UMLS:C0520853 Increased mean arterial pressure (finding) SNOMEDCT_US:26014004 Increased mean arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:26014004 UMLS:C0339794 Chronic catarrhal rhinitis (disorder) SNOMEDCT_US:266342009 Chronic catarrhal rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:266342009 UMLS:C2364009 Pneumococcal lobar pneumonia (disorder) SNOMEDCT_US:266350000 Pneumococcal lobar pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:266350000 UMLS:C0559094 Chronic chemical respiratory disease (disorder) SNOMEDCT_US:266404004 Chronic chemical respiratory disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:266404004 UMLS:C0426616 Vomiting blood - fresh (disorder) SNOMEDCT_US:267051003 Vomiting blood - fresh SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:267051003 UMLS:C0425486 Spontaneous respiratory frequency SNOMEDCT_US:271625008 Rate of spontaneous respiration SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:271625008 The maximum pressure exerted into the systemic arterial circulation during the contraction of the left ventricle of the heart. (NCI) UMLS:C0871470 SAP - Systolic arterial pressure Systolic blood pressure (observable entity) SNOMEDCT_US:271649006 Systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:271649006 The minimum pressure exerted into the systemic arterial circulation during cardiac ventricular relaxation and filling. (NCI) UMLS:C0428883 DAP - Diastolic arterial pressure DBP - Diastolic blood pressure Diastolic arterial pressure Diastolic blood pressure (observable entity) SNOMEDCT_US:271650006 Diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:271650006 Complaining of cough Complaining of cough (finding) SNOMEDCT_US:272039006 C/O - cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:272039006 UMLS:C0558520 On examination - hypothermia SNOMEDCT_US: 274307008 O/E - hypothermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 274307008 UMLS:C0423729 Chest pain on breathing (finding) SNOMEDCT_US:274664007 Chest pain on breathing SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:274664007 UMLS:C0476281 Noncardiac chest pain SNOMEDCT_US:274668005 Non-cardiac chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:274668005 UMLS:C1295773 Desulfobulbus species Genus Desulfobulbus Genus Desulfobulbus (organism) SNOMEDCT_US:27497008 Desulfobulbus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:27497008 A form of meningitis caused by LYMPHOCYTIC CHORIOMENINGITIS VIRUS. MICE and other rodents serve as the natural hosts, and infection in humans usually occurs through inhalation or ingestion of infectious particles. Clinical manifestations include an influenza-like syndrome followed by stiff neck, alterations of mentation, ATAXIA, and incontinence. Maternal infections may result in fetal malformations and injury, including neonatal HYDROCEPHALUS, aqueductal stenosis, CHORIORETINITIS, and MICROCEPHALY. (NCI) UMLS:C0024266 Lymphocytic meningitis (disorder) SNOMEDCT_US:276064006 Lymphocytic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276064006 UMLS:C0455777 Coughing ineffective (finding) SNOMEDCT_US:276314008 Coughing ineffective SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276314008 UMLS:C0456005 Newborn environmental hypothermia (disorder) SNOMEDCT_US: 276529009 Newborn environmental hypothermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 276529009 UMLS:C0456007 Avery syndrome type 1 Avery's syndrome type 1 Avery's syndrome type 1 (disorder) Mild transient tachypnoea of newborn Newborn transitory tachypnea Non-oxygen-dependent Avery's syndrome SNOMEDCT_US:276531000 Mild transient tachypnea of newborn SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276531000 UMLS:C0456008 Avery syndrome type 2 Avery's syndrome type 2 Avery's syndrome type 2 (disorder) Oxygen-dependent Avery's syndrome Severe transient tachypnoea of newborn SNOMEDCT_US:276532007 Severe transient tachypnea of newborn SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276532007 UMLS:C0349494 Congenital viral pneumonia (disorder) SNOMEDCT_US:276692000 Congenital viral pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276692000 UMLS:C0349495 Congenital bacterial pneumonia (disorder) SNOMEDCT_US:276693005 Congenital bacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276693005 UMLS:C0349497 Neonatal aspiration pneumonia (disorder) SNOMEDCT_US:276695003 Neonatal aspiration pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276695003 UMLS:C0456166 RV - Right ventricular pressure RVP - Right ventricular pressure Right ventricular pressure (observable entity) SNOMEDCT_US:276756009 Right ventricular pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276756009 UMLS:C0456179 LV - Left ventricular pressure Left ventricular pressure (observable entity) SNOMEDCT_US:276769008 Left ventricular pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276769008 The maximum pressure exerted into the systemic arterial circulation during the contraction of the right ventricle of the heart. (NCI) UMLS:C0456181 Right ventricular systolic pressure (observable entity) SNOMEDCT_US:276772001 Right ventricular systolic pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276772001 UMLS:C0456182 Right ventricular diastolic pressure (observable entity) SNOMEDCT_US:276773006 Right ventricular diastolic pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276773006 The pressure in the left ventricle at any point prior to the ejection of its contents into the aorta (systole). (NCI) UMLS:C0456189 Left ventricular systolic pressure (observable entity) SNOMEDCT_US:276769008 Left ventricular systolic pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276769008 A form of meningitis caused by LYMPHOCYTIC CHORIOMENINGITIS VIRUS. MICE and other rodents serve as the natural hosts, and infection in humans usually occurs through inhalation or ingestion of infectious particles. Clinical manifestations include an influenza-like syndrome followed by stiff neck, alterations of mentation, ATAXIA, and incontinence. Maternal infections may result in fetal malformations and injury, including neonatal HYDROCEPHALUS, aqueductal stenosis, CHORIORETINITIS, and MICROCEPHALY. (MSH) UMLS:C0024266 Lymphocytic meningoencephalitis (disorder) SNOMEDCT_US:276817007 Lymphocytic meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276817007 UMLS:C0456240 VSO:0000013 SNOMEDCT_US:276885007 Core body temperature SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276885007 UMLS:C0457451 SNOMEDCT_US:278305009 Severity score SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:278305009 UMLS:C0032300 Lobar pneumonia (disorder) SNOMEDCT:278516003 Lobar pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT:278516003 UMLS:C0235710 Chest discomfort (finding) SNOMEDCT_US:279084009 Chest discomfort SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:279084009 Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage. (NCI) UMLS:C0036974 Acute circulatory failure Circulatory collapse Peripheral circulatory failure Peripheral vascular failure Peripheral vascular shutdown Shock (disorder) Shock - physiological SNOMEDCT_US:27942005 Shock SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:27942005 UMLS:C0264568 Empyema with bronchopleural fistula (disorder) SNOMEDCT_US:28085001 Empyema with bronchopleural fistula SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:28085001 A chronic inflammation in which the NASAL MUCOSA gradually changes from a functional to a non-functional lining without mucociliary clearance. It is often accompanied by degradation of the bony TURBINATES, and the foul-smelling mucus which forms a greenish crust (ozena). (MSH) UMLS:C0035459 Atrophic rhinitis (disorder) SNOMEDCT_US:28111002 Atrophic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:28111002 UMLS:C0476280 Musculoskeletal chest pain (finding) SNOMEDCT_US:281245003 Musculoskeletal chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:281245003 Abnormal breath sounds (crackles) heard on auscultation only in the bases of the lungs. They indicate inflammation, fluid, or infection in the air sacs of the lung. (NCI) UMLS:C0240859 Basal creps Basal crepitations (finding) Basal creps SNOMEDCT_US:284520004 Basal crepitations SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:284520004 UMLS:C0562483 Persistent cough (finding) SNOMEDCT_US:284523002 Persistent cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:284523002 UMLS:C0541828 Left sided chest pain (finding) SNOMEDCT_US:285385002 Left sided chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:285385002 UMLS:C0563275 Right sided chest pain (finding) SNOMEDCT_US:285386001 Right sided chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:285386001 UMLS:C0563278 Upper chest pain (finding) SNOMEDCT_US:285389008 Upper chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:285389008 UMLS:C3839858 Chronic coccidioidomycotic pneumonia (disorder) SNOMEDCT_US:28791000119105 Chronic coccidioidomycotic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:28791000119105 UMLS:C0567366 Croupy cough (finding) SNOMEDCT_US:289965001 Croupy cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:289965001 UMLS:C0575012 Cervical spine stiff (finding) SNOMEDCT_US:298234007 Cervical spine stiff SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:298234007 Pressure, burning, or numbness in the chest. (MSH) UMLS:C0008031 SNOMEDCT_US:29857009 Chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:29857009 Test to determine the presence of blood infection (e.g. SEPSIS; BACTEREMIA). (MSH) UMLS:C0200949 SNOMEDCT_US:30088009 Blood culture SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:30088009 UMLS:C0577662 Allergic cough (finding) SNOMEDCT_US:300959008 Allergic cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:300959008 UMLS:C0577702 Basal pneumonia (disorder) Lower lobe pneumonia SNOMEDCT:300999006 Basal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT:300999006 UMLS:C0578576 LUZ - Left upper zone pneumoni Left upper lobe pneumonia Left upper zone pneumonia (disorder) Lobar pneumonia left upper lobe SNOMEDCT:301002002 Left upper zone pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT:301002002 UMLS:C0578577 Lobar pneumonia right middle lobe RMZ - Right middle zone pneumonia Right middle lobe pneumonia Right middle zone pneumonia (disorder) SNOMEDCT:301003007 Right middle zone pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT:301003007 UMLS:C0585106 Lobar pneumonia right upper lobe RUL - Right upper lobe pneumonia RUZ - Right upper zone pneumonia Right upper lobe pneumonia Right upper zone pneumonia (disorder) SNOMEDCT:301004001 Right upper zone pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT:301004001 UMLS:C0153166 Syphilitic meningitis (disorder) SNOMEDCT_US:301086002 Syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301086002 UMLS:C0577830 Observation of systemic arterial pressure SNOMEDCT_US:301140001 Finding of systemic arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301140001 UMLS:C0577831 Observation of pulmonary arterial pressure SNOMEDCT_US:301141002 Finding of pulmonary arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301141002 UMLS:C0577920 Effective cough (finding) SNOMEDCT_US:301236000 Effective cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301236000 Inflammation of the membranes surrounding the brain and spinal cord without a bacterial pathogen. (NCI) UMLS:C0025290 SNOMEDCT_US:301770000 Aseptic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301770000 UMLS:C0578502 Finding of respiratory effort (finding) Observation of respiratory effort SNOMEDCT_US:301820005 Finding of respiratory effort SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301820005 UMLS:C0338396 Proteus meningitis (disorder) SNOMEDCT_US:302877009 Proteus meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:302877009 UMLS:C0437245 Recurrent febrile convulsion (finding) Recurrent febrile fit SNOMEDCT:307200007 Recurrent febrile convulsion SNOMEDCT_US: 2021/01/06 SNOMEDCT:307200007 UMLS:C0585141 Bronchopleural subphrenic fistula (disorder) SNOMEDCT_US:307232007 Bronchopleural subphrenic fistula SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:307232007 UMLS:C0554135 Haematemesis - cause unknown Hematemesis - cause unknown (disorder) SNOMEDCT_US:308904008 Hematemesis - cause unknown SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:308904008 UMLS:C0339952 Secondary bacterial pneumonia (disorder) SNOMEDCT_US:308906005 Secondary bacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:308906005 UMLS:C0267173 Vomiting in infants AND/OR children (disorder) SNOMEDCT_US:3094009 Vomiting in infants AND/OR children SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:3094009 UMLS:C3472698 SNOMEDCT_US:311000119101 Non-allergic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:311000119101 Inflammation of the meninges due to microorganism infection. (CSP) Inflammation of the meninges of the brain and/or spinal cord caused by an infectious agent (viral, bacterial, or fungal). Symptoms include headache, fever, vomiting, neck stiffness, photophobia, confusion, and seizures. (NCI) UMLS:C0729584 Infective meningitis (disorder) SNOMEDCT_US:312216007 Infective meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:312216007 UMLS:C0729704 Infective pneumonia (disorder) SNOMEDCT_US:312342009 Infective pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:312342009 UMLS:C1282174 24 hour systolic blood pressure (observable entity) SNOMEDCT_US:314464000 24 hour systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:314464000 UMLS:C1282175 24 hour diastolic blood pressure (observable entity) SNOMEDCT_US:314465004 24 hour diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:314465004 UMLS:C1279386 Postoperative pneumonia (disorder) SNOMEDCT_US:314978007 Postoperative pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:314978007 UMLS:C0276600 Human immunodeficiency virus infection with aseptic meningitis AIDS virus with aseptic meningitis Human immunodeficiency virus (HIV) infection with aseptic meningitis Human immunodeficiency virus infection with aseptic meningitis Human immunodeficiency virus infection with aseptic meningitis (disorder) SNOMEDCT_US:315019000 HIV infection with aseptic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:315019000 UMLS:C1277590 Unexplained cough (finding) SNOMEDCT_US:315246003 Unexplained cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:315246003 UMLS:C0264521 Hypostatic bronchopneumonia (disorder) SNOMEDCT_US:31561003 Hypostatic bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:31561003 UMLS:C1277632 Target systolic blood pressure (observable entity) SNOMEDCT_US:315612005 Target systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:315612005 UMLS:C1277633 Target diastolic blood pressure (observable entity) SNOMEDCT_US:315613000 Target diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:315613000 UMLS:C0025293 Listeria meningitis (disorder) Meningitis due to listeriosis) SNOMEDCT_US:31568009 Listeria meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:31568009 UMLS:C0231867 Medium rales (finding) SNOMEDCT_US:31846006 Medium rales SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:31846006 UMLS:C0275641 Pulmonary actinobacillosis (disorder) SNOMEDCT_US:32204007 Pulmonary actinobacillosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:32204007 UMLS:C0276119 Pneumonia in Q fever (disorder) Q fever pneumonia SNOMEDCT_US:32286006 Pneumonia in Q fever SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:32286006 An inflammatory process affecting the pericardium. (NCI) UMLS:C0031046 SNOMEDCT_US:3238004 Pericarditis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:3238004 UMLS:C0521220 Aspiration of trachea with lavage (procedure) SNOMEDCT_US:332856005 Aspiration of trachea with lavage SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:332856005 UMLS:C0152165 Uncontrollable vomiting (disorder) SNOMEDCT_US:332982000 Uncontrollable vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:332982000 UMLS:C0016878 Fusobacterium species Genus Fusobacterium Genus Fusobacterium (organism) SNOMEDCT_US:33562003 Fusobacterium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:33562003 UMLS:C0232285 Dull chest pain (finding) SNOMEDCT_US:3368006 Dull chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:3368006 UMLS:C0155862 Pneumonia caused by Streptococcus Pneumonia caused by Streptococcus (disorder) Streptococcal pneumonia SNOMEDCT_US:34020007 Pneumonia due to Streptococcus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:34020007 A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule. (MSH) HP:000096 SYMP:0000537 UMLS:C0010520 SNOMEDCT_US:3415004 Cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:3415004 UMLS:C0277863 Atelectatic rales (finding) SNOMEDCT_US:34770001 Atelectatic rales SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:34770001 UMLS:C3698305 Chest pain of pericarditis SNOMEDCT_US:34791000119103 Chest pain due to pericarditis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:34791000119103 UMLS:C0153251 Candidal pneumonia Candidiasis of lung (disorder) Candidosis of lung Pulmonary candidiasis Pulmonary candidosis SNOMEDCT_US:3487004 Candidiasis of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:3487004 Making self sick Self-induced vomiting (disorder) SNOMEDCT_US:34923007 Self-induced vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:34923007 UMLS:C4023111 Acute aspiration pneumonia (disorder) SNOMEDCT_US:35031000119100 Acute aspiration pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:35031000119100 UMLS:C0393492 Epidural infratentorial pyogenic abscess SNOMEDCT_US:359844001 Extradural infratentorial pyogenic abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:359844001 UMLS:C1082690 Catonella species Genus Catonella Genus Catonella (organism) SNOMEDCT_US:363774008 Catonella SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:363774008 UMLS:C1287655 Finding related to ability to cough (finding) SNOMEDCT_US:366124008 Finding related to ability to cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:366124008 UMLS:C1287678 Finding of respiratory volume Finding of respiratory volume (finding) SNOMEDCT_US:366148004 Respiratory volume - finding SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:366148004 UMLS:C1287690 Finding of venous pressure (finding) SNOMEDCT_US:366161004 Venous pressure - finding SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:366161004 UMLS:C0235963 Ulcerative nasal mucositis SNOMEDCT_US:36669007 Ulcerative rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:36669007 A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. (NCI) UMLS:C0231218 Does not feel right Feels off-color Feels off-colour Feels poorly Feels unwell Ill-defined experience Not feeling great Not feeling well Vague bodily discomfort SNOMEDCT_US:367391008 Malaise SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:367391008 UMLS:C0232533 Oesophageal chest pain SNOMEDCT_US:36859004 Esophageal chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:36859004 UMLS:C1299600 Squeezing chest pain (finding) SNOMEDCT_US:371030007 Squeezing chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:371030007 UMLS:C0747690 Obstructive pneumonia Obstructive pneumonitis Post obstructive pneumonia Postobstructive pneumonia (disorder) Postobstructive pneumonitis SNOMEDCT_US:371072008 Postobstructive pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:371072008 UMLS:C1299571 SNOMEDCT_US:371127003 Obstructive sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:371127003 UMLS:C0233757 Functional vomiting Hysterical vomiting SNOMEDCT_US:37224001 Psychogenic vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:37224001 UMLS:C0752045 Genus Lawsonia Genus Lawsonia (organism) Lawsonia species SNOMEDCT_US:372253004 Lawsonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:372253004 UMLS:C0011731 Desulfomonas species Genus Desulfomonas Genus Desulfomonas (organism) SNOMEDCT_US:37456006 Desulfomonas SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:37456006 UMLS:C0275906 Tuberculosis of spinal meninges (disorder) SNOMEDCT_US:38115001 Tuberculosis of spinal meninges SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38115001 Pneumonia that is not acquired in a hospital or long-term care facility setting. (NCI) UMLS:C0694549 Community acquired pneumonia (disorder) SNOMEDCT_US:385093006 Community acquired pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:385093006 UMLS:C1217397 Genus Caldimonas Genus Caldimonas (organism) SNOMEDCT_US:385459001 Caldimonas SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:385459001 UMLS:C1622996 Genus Methanobrevibacter Genus Methanobrevibacter (organism) SNOMEDCT_US:115101008 Methanobrevibacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115101008 UMLS:C0270148 Cyanotic attacks of newborn Perinatal cyanotic attacks (disorder) SNOMEDCT_US:38593000 Perinatal cyanotic attacks SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38593000 Abnormally low body temperature. (NCI) HP:0002045 MSH:D007035 SYMP:0000302 UMLS:C0020672 Decreased body temperature SNOMEDCT_US:386689009 Hypothermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:386689009 UMLS:C0232601 Concealed vomiting (disorder) Surreptitious vomiting SNOMEDCT_US:38685005 Concealed vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38685005 UMLS:C0276678 American histoplasmosis with pneumonia Pneumonia caused by Histoplasma capsulatum Pneumonia caused by Histoplasma capsulatum (disorder) SNOMEDCT_US:38699009 Pneumonia due to histoplasma capsulatum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38699009 UMLS:C0005826 SNOMEDCT_US:38936003 Abnormal blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38936003 UMLS:C0524688 Pneumonic plague (disorder) SNOMEDCT_US:38976008 Pneumonic plague SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:38976008 A test result that reports the diastolic and systolic pressure of the blood. (NCI) UMLS:C1271104 SNOMEDCT_US:392570002 Blood pressure finding SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:392570002 UMLS:C1271105 Finding of arterial pulse pressure (finding) SNOMEDCT_US:392571003 Finding of arterial pulse pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:392571003 Acute inflammation of the walls of the terminal bronchioles that spreads into the peribronchial alveoli and alveolar ducts. It results in the creation of foci of consolidation, which are surrounded by normal parenchyma. It affects one or more lobes, and is frequently bilateral and basal. It is usually caused by bacteria (e.g., Staphylococcus, Streptococcus, Haemophilus influenzae). Signs and symptoms include fever, cough with production of brown-red sputum, dyspnea, and chest pain. (NCI) UMLS:C0006285 Bronchial pneumonia Bronchopneumonia (disorder) Lobular pneumonia SNOMEDCT_US:396285007 Bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:396285007 UMLS:C1300643 Bilateral bronchopneumonia (disorder) SNOMEDCT_US:396286008 Bilateral bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:396286008 The time elapsed since birth. (NCI) UMLS:C0001779 Age - descriptor SNOMEDCT_US:397669002 Age SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:397669002 A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death. (NCI) UMLS:C1175175 SARS SARS-CoV infection Severe acute respiratory syndrome (disorder) SNOMEDCT_US:398447004 Severe acute respiratory syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:398447004 UMLS:C1302171 SNOMEDCT_US:399017001 Heart rate on admission SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:399017001 UMLS:C1302311 Systolic blood pressure on admission (observable entity) SNOMEDCT_US:399304008 Systolic blood pressure on admission SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:399304008 UMLS:C1303018 Standing systolic blood pressure(observable entity) SNOMEDCT_US:400974009 Standing systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:400974009 UMLS:C1303019 Standing diastolic blood pressure (observable entity) SNOMEDCT_US:400975005 Standing diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:400975005 UMLS:C0278138 SNOMEDCT_US:40196000 Mild pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:40196000 UMLS:C1274675 SNOMEDCT_US:403299004 Clubbing of nails associated with systemic disorder SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:403299004 UMLS:C0024591 MH - Malignant hyperpyrexia MHS - Malignant hyperthermia Malignant hyperthermia (finding) SNOMEDCT_US:405501007 Malignant hyperthermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:405501007 UMLS:C1320835 Drug fever Drug-induced hyperpyrexia (finding) SNOMEDCT_US:405543000 Drug-induced hyperpyrexia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:405543000 UMLS:C1318998 Traumatic bronchopleural fistula (disorder) SNOMEDCT_US:405586000 Traumatic bronchopleural fistula SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:405586000 UMLS:C0302133 Mottled skin SNOMEDCT_US:406128001 Mottling of skin SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:406128001 UMLS:C1319893 Sitting systolic blood pressure (observable entity) SNOMEDCT_US:407554009 Sitting systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:407554009 UMLS:C1319894 Sitting diastolic blood pressure (observable entity) SNOMEDCT_US:407555005 Sitting diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:407555005 UMLS:C1319895 Lying systolic blood pressure (observable entity) SNOMEDCT_US:407556006 Lying systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:407556006 UMLS:C1319896 Lying diastolic blood pressure (observable entity) SNOMEDCT_US:407557002 Lying diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:407557002 UMLS:C1142578 Bilateral pneumonia (disorder) SNOMEDCT_US:407671000 Bilateral pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:407671000 UMLS:C0264388 Aspiration pneumonia caused by regurgitated gastric secretions Aspiration pneumonia caused by regurgitated gastric secretions (disorder) SNOMEDCT_US:40786001 Aspiration pneumonia due to regurgitated gastric secretions SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:40786001 UMLS:C1319561 SNOMEDCT_US:408243000 Urinary pneumococcal antigen test SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:408243000 UMLS:C1510416 Coffee ground emesis Coffee ground vomiting (disorder) Vomiting blood - coffee ground Vomiting old blood SNOMEDCT_US:40835002 Coffee ground vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:40835002 UMLS:C1443238 Healthcare associated bacterial pneumonia (disorder) SNOMEDCT_US:408680002 Healthcare associated bacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:408680002 UMLS:C1443239 Healthcare associated legionnaire disease Healthcare associated legionnaire's disease Healthcare associated legionnaire's disease (disorder) SNOMEDCT_US:408681003 Healthcare associated Legionnaires' disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:408681003 An infection that is caused by Bacillus anthracis, which is usually acquired by contact with infected animals, contaminated animal products, or directly from soil; it may affect the lungs, gastrointestinal tract, skin, and/or central nervous system. (NCI) MESH:D000881 UMLS:C0003175 Anthrax (disorder) Charbon Infection due to Bacillus anthracis Milzbrand Nausea Skin ulcer SNOMEDCT_US:409498004 Anthrax SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409498004 UMLS:C1443847 haemorrhagic meningitis SNOMEDCT_US:409501004 Haemorrhagic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409501004 UMLS:C1443894 Q fever aseptic meningitis (disorder) SNOMEDCT_US:409555000 Q fever aseptic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409555000 UMLS:C1443924 Severe diarrhoea SNOMEDCT_US:409587002 Severe diarrhea SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409587002 UMLS:C0277877 Pulmonary infiltrate Radiologic infiltrate of lung (disorder) SNOMEDCT_US:409609008 Radiologic infiltrate of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409609008 UMLS:C1443976 Pneumonia caused by anaerobic bacteria Pneumonia caused by anaerobic bacteria (disorder) SNOMEDCT_US:409664000 Pneumonia due to anaerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409664000 UMLS:C1443977 Pneumonia caused by aerobic bacteria Pneumonia caused by aerobic bacteria (disorder) SNOMEDCT_US:409665004 Pneumonia due to aerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409665004 UMLS:C1080715 Family Alcaligenaceae Family Alcaligenaceae (organism) SNOMEDCT_US:409866001 Alcaligenaceae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:409866001 UMLS:C0264271 SNOMEDCT_US:40988009 Obstructive rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:40988009 UMLS:C0318339 Chlamydia psittaci var. bovis Chlamydophila psittaci var. bovis Chlamydophila psittaci variant bovis (organism) SNOMEDCT_US:41090000 Chlamydophila psittaci variant bovis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41090000 UMLS:C0276156 Adenoviral pneumonia (disorder) SNOMEDCT_US:41207000 Adenoviral pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41207000 UMLS:C0276344 Influenza with bronchopneumonia Influenzal bronchopneumonia (disorder) SNOMEDCT_US:41269000 Influenzal bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41269000 UMLS:C0204815 Suction and cleaning of tracheostomy tube (procedure) SNOMEDCT_US:41351007 Suction and cleaning of tracheostomy tube SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41351007 UMLS:C0189351 Nasotracheal aspiration (procedure) Nasotracheal suction Tracheal suction via nose SNOMEDCT_US:41360004 Nasotracheal aspiration SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41360004 UMLS:C0155860 Pneumonia caused by Pseudomonas Pneumonia caused by Pseudomonas (disorder) Pseudomonal pneumonia SNOMEDCT_US:41381004 Pneumonia due to Pseudomonas SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41381004 UMLS:C1622996 Class Clostridia (organism) Clostridia SNOMEDCT_US:115101008 Class Clostridia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115101008 Febrile seizures are convulsions induced by a fever in infants or small children and are generally characterized by loss of consciousness and tonic-clonic movements. Most febrile seizures last a minute or two. (HPO) Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784). (MSH) MSH:D003294 SYMP:0000595 UMLS:C0009952 Febrile convulsion (finding) Febrile fit Febrile seizure Febrile seizure (from fever) Fever seizure Pyrexial convulsion SNOMEDCT:41497008 Febrile convulsion SNOMEDCT_US: 2021/01/06 SNOMEDCT:41497008 Pneumonia resulting from infection with Pneumocystis jirovecii, frequently seen in the immunologically compromised, such as persons with AIDS, or steroid-treated individuals, the elderly, or premature or debilitated babies during their first three months. Patients may be only slightly febrile (or even afebrile), but are likely to be extremely weak, dyspneic, and cyanotic. This is a major cause of morbidity among patients with AIDS. (NCI) UMLS:C1535939 PCP - Pneumocystis pneumonia Pneumocystosis jirovecii pneumonia Pneumocystosis jirovecii pneumonia (disorder) Pulmonary pneumocystosis SNOMEDCT_US:415125002 Pneumocystosis pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:415125002 UMLS:C1532934 Obligate anaerobe Strict anaerobe Strict anaerobic bacteria (organism) SNOMEDCT_US:415626000 Strict anaerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:415626000 UMLS:C1036530 Cryptobacterium species Genus Cryptobacterium Genus Cryptobacterium (organism) SNOMEDCT_US:416082009 Cryptobacterium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:416082009 UMLS:C1563031 Curved Gram-negative bacillus (organism) SNOMEDCT_US:416517000 Curved gram-negative bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:416517000 UMLS:C1065645 Catenibacterium species Genus Catenibacterium Genus Catenibacterium (organism) SNOMEDCT_US:417391005 Catenibacterium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:417391005 UMLS:C1642397 Respiratory tract congestion and cough (disorder) SNOMEDCT_US:417850002 Respiratory tract congestion and cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:417850002 UMLS:C1626406 Eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis Eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis (disorder) SNOMEDCT_US:418480000 Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:418480000 UMLS:C4040431 SNOMEDCT_US:41931000119102 Sinusitis co-occurrent with nasal polyps SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:41931000119102 UMLS:C0995456 BCF group Bacteroides-Cytophaga-Flexibacter group CFB group Cytophaga-Flexibacter-Bacteroides phylum Phylum Bacteroidetes Phylum Bacteroidetes (organism) SNOMEDCT_US:419548007 Bacteroidetes SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:419548007 UMLS:C0264390 Aspiration pneumonia caused by inhalation of vomitus Aspiration pneumonia caused by inhalation of vomitus (disorder) SNOMEDCT_US:42004004 Aspiration pneumonia due to inhalation of vomitus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:42004004 UMLS:C0276523 Bacterial pneumonia associated with acquired immunodeficiency syndrome Bacterial pneumonia associated with acquired immunodeficiency syndrome (disorder) SNOMEDCT_US:420544002 Bacterial pneumonia associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:420544002 UMLS:C1719906 Meningitis caused by Aerobacter aerogenes SNOMEDCT_US:420585007 Meningitis caused by Klebsiella aerogenes SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:420585007 UMLS:C1720231 Malaise associated with acquired immunodeficiency syndrome Malaise associated with acquired immunodeficiency syndrome (disorder) SNOMEDCT_US:420801006 Malaise associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:420801006 UMLS:C1720342 Fatigue associated with acquired immunodeficiency syndrome Fatigue associated with acquired immunodeficiency syndrome (disorder) SNOMEDCT_US:420900006 Fatigue associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:420900006 UMLS:C0276502 Candidiasis of lung associated with acquired immunodeficiency syndrome Candidiasis of lung associated with acquired immunodeficiency syndrome (disorder) SNOMEDCT_US:421047005 Candidiasis of lung associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:421047005 UMLS:C0276528 Viral pneumonia associated with acquired immunodeficiency syndrome Viral pneumonia associated with acquired immunodeficiency syndrome (disorder) SNOMEDCT_US:421508002 Viral pneumonia associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:421508002 UMLS:C0276527 Pneumonia associated with acquired immunodeficiency syndrome SNOMEDCT_US:421671002 Pneumonia associated with AIDS SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:421671002 Purulent sputum contains pus, composed of white blood cells, cellular debris, dead tissue, serous fluid, and viscous liquid (mucus). Purulent sputum is typically yellow or green. UMLS:C0241235 Purulent sputum (finding) SNOMEDCT_US:42192008 Purulent sputum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:42192008 UMLS:C1720094 Heart rate measured at brachial artery SNOMEDCT:422119006 Brachial pulse rate SNOMEDCT_US: 2021/01/06 SNOMEDCT:422119006 The forcible expulsion of the contents of the STOMACH through the MOUTH. (MSH) Vomiting is a digestive system symptom characterized by throwing up the stomach contents. (SYMP) MEDDRA:10047700 MSH:D014839 SNOMEDCT_US:300359004 UMLS:C0042963 emesis throwing-up SNOMEDCT_US:422400008 Vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:422400008 UMLS:C0032290 Aspiration pneumonia (disorder) Inhalation pneumonia SNOMEDCT_US:422588002 Aspiration pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:422588002 Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales. (NCI) Heart failure accompanied by EDEMA, such as swelling of the legs and ankles and congestion in the lungs. (MSH) UMLS:C0018802 CCF - Congestive cardiac failure CHF - Congestive heart failure Congestive cardiac failure Congestive heart failure (disorder) SNOMEDCT_US:42343007 Congestive heart failure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:42343007 UMLS:C0995983 Genus Acetonema Genus Acetonema (organism) SNOMEDCT_US:423591008 Acetonema SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:423591008 UMLS:C1532372 Respiratory secretion (substance) SNOMEDCT_US:423662002 Respiratory secretion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:423662002 UMLS:C1740793 Vomiting after coughing SNOMEDCT_US:424580008 Post-tussive vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:424580008 UMLS:C1827192 SNOMEDCT:425011002 Allergic fungal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT:425011002 UMLS:C0949083 HAP - hospital acquired pneumonia Nosocomial pneumonia Nosocomial pneumonia (disorder) SNOMEDCT_US:425464007 Hospital acquired pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:425464007 UMLS:C0854215 Bacterial meningitis caused by Gram-negative bacteria Bacterial meningitis caused by Gram-negative bacteria (disorder) Gram-negative bacterial meningitis Meningitis with gram negative bacteria SNOMEDCT_US:425887005 Bacterial meningitis due to Gram-negative bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:425887005 UMLS:C1960025 Bilateral basal pneumonia (disorder) Bilateral lower lobe pneumonia SNOMEDCT_US:425996009 Bilateral basal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:425996009 A malignant neoplasm that has spread from its original site of growth to the leptomeninges. (NCI). UMLS:C1704231 Lymphomatous meningitis (disorder) SNOMEDCT_US:426128009 Lymphomatous meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:426128009 UMLS:C0423636 Cardiac chest pain (finding) SNOMEDCT_US:426396005 Cardiac chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:426396005 UMLS:C4721952 Familial idiopathic pulmonary fibrosis (disorder) SNOMEDCT_US:426437004 Familial idiopathic pulmonary fibrosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:426437004 UMLS:C4542873 Gilardi rod group 1 (organism) SNOMEDCT_US:426709007 Gilardi rod group 1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:426709007 UMLS:C0264510 Endogenous lipoid pneumonia (disorder) SNOMEDCT_US:42680007 Endogenous lipoid pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:42680007 UMLS:C1041742 Genus Aquabacterium Genus Aquabacterium (organism) SNOMEDCT_US:428044007 Aquabacterium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:428044007 UMLS:C1998267 SNOMEDCT_US:428869006 Mixed rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:428869006 UMLS:C1701940 VAP - ventilator associated pneumonia Ventilator-acquired pneumonia Ventilator-acquired pneumonia (disorder) Ventilator-associated pneumonia SNOMEDCT_US:429271009 Ventilator associated pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:429271009 UMLS:C1998143 SNOMEDCT_US:429427008 Invasive fungal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:429427008 UMLS:C1997492 Heart rate measured at dorsalis pedis artery SNOMEDCT_US:429525003 Dorsalis pedis pulse rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:429525003 UMLS:C1997188 Heart rate measured at posterior tibial artery (observable entity) SNOMEDCT_US:429614003 Posterior tibial pulse rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:429614003 UMLS:C3494774 Tubular meningitis SNOMEDCT_US:429741000124103 Basilar meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:429741000124103 UMLS:C0231911 Fit of coughing Bout of coughing Fit of coughing Paroxysm of coughing Paroxysmal cough (finding) SNOMEDCT_US:43025008 Paroxysmal cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:43025008 UMLS:C0854248 Gram negative pneumonia Pneumonia caused by Gram-negative bacteria Pneumonia due to Gram-negative bacteria SNOMEDCT_US:430395005 Pneumonia caused by Gram negative bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:430395005 UMLS:C0747651 Recurrent aspiration pneumonia (disorder) SNOMEDCT_US:430969000 Recurrent aspiration pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:430969000 UMLS:C1002319 Genus Caedibacter Genus Caedibacter (organism) SNOMEDCT_US:431101009 Caedibacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:431101009 UMLS:C2317131 Acute rhinosinusitis (disorder) SNOMEDCT_US:431231008 Acute rhinosinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:431231008 UMLS:C0149886 Simple febrile convulsion Simple febrile seizure (finding) SNOMEDCT:432354000 Simple febrile seizure SNOMEDCT_US: 2021/01/06 SNOMEDCT:432354000 UMLS:C1006471 Genus Ideonella Genus Ideonella (organism) SNOMEDCT_US:433045003 Ideonella SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:433045003 UMLS:C0751057 Complex febrile convulsion Complex febrile seizure (finding) SNOMEDCT:433083002 Complex febrile seizure SNOMEDCT_US: 2021/01/06 SNOMEDCT:433083002 UMLS:C1740831 Chronic chest pain (finding) SNOMEDCT_US:434011000124101 Chronic chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:434011000124101 UMLS:C0746105 Chronic infiltrative lung disease Chronic interstitial lung disease (disorder) SNOMEDCT_US:434301000124102 Chronic interstitial lung disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:434301000124102 UMLS:C3661902 Pneumonia due to Influenza A virus (disorder) SNOMEDCT_US:434921000124108 Pneumonia due to Influenza A virus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:434921000124108 UMLS:C0263538 Club nail Clubbing of nail (disorder) Hippocratic nail Hippocratic nails Increased curvature of nails SNOMEDCT_US:4373005 Clubbing of nail SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:4373005 UMLS:C2585749 Postoperative aspiration pneumonia (disorder) SNOMEDCT_US:438764004 Postoperative aspiration pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:438764004 UMLS:C2584534 Genus Pseudocaedibacter Genus Pseudocaedibacter (organism) SNOMEDCT_US:440127003 Pseudocaedibacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:440127003 UMLS:C2349530 Pneumonia caused by Staphylococcus aureus SNOMEDCT:US:441658007 Pneumonia due to Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT:US:441658007 UMLS:C1904168 Herminiimonas saxobsidens (organism) SNOMEDCT_US:441659004 Herminiimonas saxobsidens SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:441659004 C2711710 Imaging of lung (procedure) SNOMEDCT_US:441677009 Imaging of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:441677009 Complete or severe loss of the subjective sense of smell. Loss of smell may be caused by many factors such as cold, allergy, OLFACTORY NERVE DISEASES; viral RESPIRATORY TRACT INFECTIONS (e.g., COVID-19), aging and various neurological disorders (e.g., ALZHEIMER DISEASE). (MSH) HP:0000458 UMLS:C0003126 Absent smell Anosmia Anosmia (loss of sense of smell) Loss of sense of smell (finding) Loss of the sense of smell No sense of smell Sense of smell absent Sense of smell lost SNOMEDCT_US:44169009 Loss of sense of smell SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:44169009 UMLS:C2062470 Group A streptococcal pneumonia Pneumonia caused by infection by Streptococcus pyogenes Pneumonia caused by infection caused by Streptococcus pyogenes Pneumonia caused by infection caused by Streptococcus pyogenes (disorder) Pneumonia due to infection caused by Streptococcus pyogenes SNOMEDCT_US:441942006 Pneumonia caused by infection caused by streptococcus pyogenes SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:441942006 UMLS:C2711145 Pneumonia caused by Histoplasma Pneumonia caused by Histoplasma (disorder) SNOMEDCT_US:442094008 Pneumonia due to Histoplasma SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:442094008 UMLS:C2711755 Psychogenic fatigue (finding) SNOMEDCT_US:442099003 Psychogenic fatigue SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:442099003 UMLS:C1615607 SNOMEDCT_US:442352004 Influenza A virus subtype H1N1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:442352004 UMLS:C0235250 Hyperemesis (disorder) SNOMEDCT_US:444673007 Hyperemesis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:444673007 UMLS:C0748731 SNOMEDCT_US:444814009 Viral sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:444814009 UMLS:C3853138 SNOMEDCT_US:444851000124109 Very mild pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:444851000124109 UMLS:C1389235 Bacterial meningomyelitis (disorder) SNOMEDCT_US:444957003 Bacterial meningomyelitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:444957003 UMLS:C1821417 SNOMEDCT_US:444981005 Resting heart rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:444981005 UMLS:C0854214 Meningitis caused by anaerobic bacteria SNOMEDCT_US:445059005 Meningitis due to anaerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445059005 UMLS:C2919364 Pneumonia caused by Human metapneumovirus Pneumonia caused by Human metapneumovirus (disorder) SNOMEDCT_US:445096001 Pneumonia due to Human metapneumovirus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445096001 UMLS:C2919453 Persistent cough after viral respiratory infection (disorder) Persistent cough after viral respiratory infection Persistent cough after viral respiratory infection (disorder) SNOMEDCT_US:445241004 Postviral cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445241004 UMLS:C0920250 Bacterial meningoencephalitis (disorder) SNOMEDCT_US:445359003 Bacterial meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445359003 UMLS:C2919914 Anaerobic Gram negative coccobacillus (organism) SNOMEDCT_US:445380009 Anaerobic Gram negative coccobacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445380009 UMLS:C2919913 Anaerobic Gram positive coccobacillus (organism)) SNOMEDCT_US:445381008 Anaerobic Gram positive coccobacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:445381008 UMLS:C0274383 Aspiration pneumonia resulting from a procedure (disorder) SNOMEDCT_US:44549008 Aspiration pneumonia resulting from a procedure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:44549008 UMLS:C3872655 Diastolic blood pressure on admission (observable entity) SNOMEDCT_US:446226005 Diastolic blood pressure on admission SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446226005 UMLS:C2960780 Influenza A virus subtype H1 (organism) SNOMEDCT_US:446396002 Influenza A virus subtype H1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446396002 UMLS:C2960813 Influenza A virus subtype H2 (organism) SNOMEDCT_US:446397006 Influenza A virus subtype H2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446397006 UMLS:C2959745 SNOMEDCT_US:446524007 Influenza A virus A/Leningrad/621/86 (H1N1) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446524007 UMLS:C2960370 SNOMEDCT_US:446525008 Influenza A virus A/Leningrad/624/86 (H1N1) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446525008 UMLS:C1385638 Pulmonary tuberculous abscess Tuberculous abscess of lung (disorder) SNOMEDCT_US:446543007 Tuberculous abscess of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446543007 UMLS:C2959654 Influenza A virus subtype H3 (organism) SNOMEDCT_US:446645007 Influenza A virus subtype H3 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446645007 UMLS:C1615053 SNOMEDCT_US:446646008 Influenza A virus subtype H3N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446646008 UMLS:C2959999 Influenza A virus subtype H5 (organism) SNOMEDCT_US:446647004 Influenza A virus subtype H5 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446647004 UMLS:C2959443 Influenza A virus subtype H7 (organism) SNOMEDCT_US:446648009 Influenza A virus subtype H7 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446648009 UMLS:C2959444 Influenza A virus subtype H9 (organism) SNOMEDCT_US:446649001 Influenza A virus subtype H9 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:446649001 UMLS:C2959924 Genus Flavonifractor Genus Flavonifractor (organism) SNOMEDCT_US:447035004 Flavonifractor SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447035004 UMLS:C2959477 Genus Pseudoflavonifractor (organism) Pseudoflavonifractor SNOMEDCT_US:447037007 Genus pseudoflavonifractor SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447037007 UMLS:C2959548 SNOMEDCT_US:447493004 Influenza A virus A/Bangkok/1/79 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447493004 UMLS:C2960184 SNOMEDCT_US:447499000 Influenza A virus A/Bangkok/2/79 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447499000 UMLS:C2959979 SNOMEDCT_US:447503006 Influenza A virus A/Port Chalmers/1/73 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447503006 UMLS:C2959631 SNOMEDCT_US:447504000 Influenza A virus A/Texas/1/77 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447504000 UMLS:C2959743 SNOMEDCT_US:447508002 Influenza A virus A/Leningrad/385/80 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447508002 UMLS:C2959645 SNOMEDCT_US:447522002 Influenza A virus A/Mississippi/1/85 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447522002 UMLS:C2960084 SNOMEDCT_US:447530001 Influenza A virus A/Philippines/2/82 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447530001 UMLS:C2960406 SNOMEDCT_US:447573005 Influenza A virus A/England/42/72 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447573005 UMLS:C2960185 SNOMEDCT_US:447578001 Influenza A virus A/Hong Kong/1/68 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447578001 UMLS:C2959719 SNOMEDCT_US:447587005 Influenza A virus A/Victoria/3/75 (H3N2) SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:447587005 MSH | A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 9 and neuraminidase 2. The H9N2 subtype usually infects domestic birds (POULTRY) but there have been some human infections reported. UMLS:C1612293 SNOMEDCT_US:448325003 Influenza A virus subtype H9N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:448325003 UMLS:C3165061 Influenza A virus subtype N1 (organism) SNOMEDCT_US:448803002 Influenza A virus subtype N1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:448803002 UMLS:C3165210 Influenza A virus subtype N2 (organism) SNOMEDCT_US:448835002 Influenza A virus subtype N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:448835002 UMLS:C3164943 SNOMEDCT_US:449024000 Pandemic influenza A (H1N1) 2009 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:449024000 UMLS:C3165178 Therapeutic suctioning of trachea via tracheostomy (procedure) SNOMEDCT_US:449229004 Therapeutic suctioning of trachea via tracheostomy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:449229004 A condition in which the blood pressure is less than the below the fifth percentile or below 2 standard deviations of the mean for age and sex. (NCI) UMLS:C0020649 Arterial hypotension Hypopiesis Hypotension Low blood pressure (disorder) SNOMEDCT_US:45007003 Low blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:45007003 UMLS:C0153256 Candidal meningitis (disorder) SNOMEDCT_US:45021001 Candidal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:45021001 UMLS:C3472265 SNOMEDCT_US:450480003 Influenza A virus subtype H3N2v SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:450480003 UMLS:C0154639 Streptococcal meningitis (disorder) SNOMEDCT_US:4510004 Streptococcal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:4510004 UMLS:C0339956 Pneumonia in typhoid fever (disorder) Typhoid pneumonia SNOMEDCT_US:45312009 Pneumonia in typhoid fever SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:45312009 UMLS:C0339946 Bronchopneumonic tularaemia Bronchopneumonic tularemia Pneumonia with tularaemia Pneumonia with tularemia Pneumonic tularaemia Pneumonic tularemia Pulmonary tularaemia Pulmonary tularemia (disorder) Tularaemia pneumonia Tularemia pneumonia SNOMEDCT_US:45556008 Pulmonary tularemia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:45556008 UMLS:C0270529 Erotic vomiting (disorder) SNOMEDCT_US:45994004 Erotic vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:45994004 A type of fungal meningitis caused by dissemination of coccidioides to to basilar meninges. Coccidioides species are soil-dwelling fungi that are the causative pathogen of coccidioidomycosis, also known as Valley fever. Infection occurs from inhalation of fungal spores that become airborne from soil in endemic regions. Sixty percent of infections are asymptomatic. The rate of dissemination from primary infection to extrapulomonary sites is higher in immune-compromised individuals. A common site of dissemination is to the basilar meninges, resulting in coccidioidal meningitis. (HPO) Coccidioidal meningitis (disorder) Coccidioidomycosis meningitis SNOMEDCT_US:46303000 Coccidioidal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:46303000 UMLS:C0231916 Cough after eating (finding) SNOMEDCT_US:46789001 Cough after eating SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:46789001 UMLS:C0264345 Cigarette cough Cigarette cough Smokers' cough (disorder) SNOMEDCT_US:46802002 Smokers' cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:46802002 UMLS:C0032302 Mycoplasma pneumonia SNOMEDCT_US:46970008 Mycoplasma pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:46970008 UMLS:C0747674 Cavitary pneumonia (disorder) SNOMEDCT_US:471272001 Cavitary pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:471272001 UMLS:C0425543 Coarse respiratory crackles (finding) Coarse respiratory crepitations SNOMEDCT_US:47525004 Coarse respiratory crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:47525004 Rales are fine, discontinuous crackles that can sound like cellophane being crumpled or velcro being pulled apart. They may be heard with a stethoscope when listening over lungs containing more than the normal amount of fluid secretiions. Crackles are discontinuous, explosive, and nonmusical adventitious lung sounds normally heard in inspiration and sometimes during expiration. Crackles are usually classified as fine and coarse crackles based on their duration, loudness, pitch, timing in the respiratory cycle, and relationship to coughing and changing body position. (HPO) HP:0030830 UMLS:C0034642 Crackles Rales Respiratory crackles (finding) Respiratory crepitations SNOMEDCT_US:48409008 Respiratory crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:48409008 UMLS:C0267172 Habit vomiting (disorder) SNOMEDCT_US:49206006 Habit vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:49206006 A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. (NCI) A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. (MSH) Coughing is a reflex that keeps your throat and airways clear. Although it can be annoying, coughing helps your body heal or protect itself. Coughs can be either acute or chronic. Acute coughs begin suddenly and usually last no more than 2 to 3 weeks. Acute coughs are the kind you most often get with a cold, flu, or acute bronchitis. Chronic coughs last longer than 2 to 3 weeks. (MEDLINEPLUS) HP:0012735 MSH:D003371 SNOMEDCT_US:263731006 SNOMEDCT_US:272039006 UMLS:C0010200 coughing SNOMEDCT_US:49727002 Cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:49727002 UMLS:C0277888 Abnormal diastolic arterial Abnormal diastolic arterial pressure (finding) Abnormal diastolic blood pressure SNOMEDCT_US:49844009 Abnormal diastolic arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:49844009 UMLS:C0278139 SNOMEDCT_US:50415004 Moderate pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:50415004 UMLS:C0149725 SNOMEDCT:50417007 Lower respiratory tract infection SNOMEDCT_US: 2021/01/06 SNOMEDCT:50417007 UMLS:C0264380 Catarrhal pneumonia (disorder) SNOMEDCT_US:50804000 Catarrhal pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:50804000 MSH/null - An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111) UMLS:C0025295 Meningtitis due to Streptococcal pneumoniae SNOMEDCT_US:51169003 Pneumococcal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:51169003 UMLS:C0037997 Disorder of spleen (disorder) Spleen disease Splenic disease Splenic disorder SNOMEDCT_US:51244008 Disorder of spleen SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:51244008 UMLS:C0276089 Escherichia coli pneumonia Pneumonia caused by E. coli Pneumonia caused by Escherichia coli Pneumonia caused by Escherichia coli (disorder) Pneumonia due to E. coli SNOMEDCT_US:51530003 Pneumonia due to Escherichia coli SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:51530003 UMLS:C0399401 Erosion of teeth due to persistent vomiting (disorder) Teeth erosion due to vomiting SNOMEDCT_US:52031007 Erosion of teeth due to persistent vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:52031007 UMLS:C0189349 Aspiration of trachea, percutaneous (procedure) Tracheal puncture, percutaneous for aspiration of mucus SNOMEDCT_US:52176005 Aspiration of trachea, percutaneous SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:52176005 UMLS:C0348061 Genus Leptotrichia Genus Leptotrichia (organism) Leptotrichia species SNOMEDCT_US:52505003 Leptotrichia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:52505003 UMLS:C0151574 Decreased coughing (finding) SNOMEDCT_US:52673003 Decreased coughing SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:52673003 A pneumonia involving inflammation of the lungs caused by bacteria. (DOID) DOID:874 MESH:D018410 UMLS:C0004626 SNOMEDCT_US:53084003 Bacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:53084003 UMLS:C0024902 Breast pain Breast painful Mastalgia Mastodynia Pain in the breast Pain of breast(finding) Painful breasts SNOMEDCT_US:53430007 Pain of breast SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:53430007 The removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. (NCI) UMLS:C0005558 BBx - Bronchoscopy and biopsy Bronchoscopy and biopsy Bronchoscopy with biopsy (procedure) Endoscopy of bronchus with biopsy SNOMEDCT_US:55198006 Bronchoscopy with biopsy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55198006 UMLS:C0221397 Eosinophilic meningoencephalitis (disorder) SNOMEDCT_US:55489003 Eosinophilic meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55489003 UMLS:C0795686 Meningitis due to trypanosomiasis SNOMEDCT_US:5566009 Trypanosomiasis with meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:5566009 UMLS:C0264377 Peribronchial pneumonia (disorder) SNOMEDCT_US:55679008 Peribronchial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55679008 UMLS:C0314858 Anaerovibrio species Genus Anaerovibrio Genus Anaerovibrio (organism) SNOMEDCT_US:55685001 Anaerovibrio SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55685001 UMLS:C0314854 Anaerobiospirillum species Genus Anaerobiospirillum Genus Anaerobiospirillum (organism) SNOMEDCT_US:55757006 Anaerobiospirillum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55757006 UMLS:C0315210 Budvicia species Genus Budvicia Genus Budvicia(organism) SNOMEDCT_US:55851000 Budvicia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55851000 The measurement of the mean left pulmonary arterial pressure, as measured by a catheter introduced into the distal pulmonary artery, is low. (NCI) UMLS:C0520851 Decreased arterial wedge pressure Decreased pulmonary arterial wedge pressure (finding) Decreased pulmonary capillary wedge pressure SNOMEDCT_US:55973006 Decreased pulmonary arterial wedge pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:55973006 Physical and psychological dependence on nicotine. (NCI) UMLS:C0028043 Nicotine dependence (disorder) SNOMEDCT_US:56294008 Nicotine dependence SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:56294008 UMLS:C0231227 SNOMEDCT_US:57494004 Senile exhaustion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:57494004 UMLS:C0264381 Unresolved pneumonia (disorder) SNOMEDCT_US:57702005 Unresolved pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:57702005 Inflammation of the membranes surrounding the brain and spinal cord due to a viral infection. (NCI) UMLS:C0025297 Abacterial meningitis Aseptic meningitis, viral Meningitis, viral Viral meningitis (disorder) SNOMEDCT_US:58170007 Viral meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:58170007 UMLS:C0041318 TB - Tuberculous meningitis TBM - Tuberculous meningitis Tuberculous meningitis SNOMEDCT_US:58437007 Tuberculosis of meninges SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:58437007 UMLS:C0264229 Acute empyema of nasal sinus (disorder) SNOMEDCT:58763001 Acute empyema of nasal sinus SNOMEDCT_US: 2021/01/06 SNOMEDCT:58763001 UMLS:C0238844 SNOMEDCT_US:58840004 Decreased breath sounds SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:58840004 UMLS:C0276155 Adenoviral bronchopneumonia (disorder) SNOMEDCT_US:58890000 Adenoviral bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:58890000 UMLS:C0232290 Crushing chest pain (finding) SNOMEDCT_US:59139008 Crushing chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:59139008 UMLS:C0004613 Anaerobe Anaerobic bacteria (organism) Anaerobic bacterium SNOMEDCT_US:59343002 Anaerobic bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:59343002 UMLS:C0155865 Pneumonia in pertussis (disorder) Pneumonia in whooping cough Pneumonia with pertussis Pneumonia with whooping cough SNOMEDCT_US:59475000 Pneumonia in pertussis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:59475000 UMLS:C0032241 Pleurobronchopneumonia (disorder) Pleuropneumonia SNOMEDCT_US:60485005 Pleurobronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:60485005 UMLS:C0318340 Chlamydia psittaci var. felis Chlamydophila psittaci var. felis Chlamydophila psittaci variant felis (organism) SNOMEDCT_US:60927005 Chlamydophila psittaci variant felis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:60927005 MSH | A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 7 and neuraminidase 9. This avian origin virus was first identified in humans in 2013. UMLS:C3658219 SNOMEDCT_US:609444009 Influenza A virus subtype H7N9 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:609444009 An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. (DOID) DOID:8468 UMLS:C0021400 Flu Grippe Influenza (disorder) SNOMEDCT_US:6142004 Influenza SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:6142004 UMLS:C0276071 Achromobacter pneumonia (disorder) SNOMEDCT_US:61884008 Achromobacter pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:61884008 The deep short sound characteristic of a hog. UMLS:C0234892 Grunting Grunting respiration (finding) SNOMEDCT_US:62085005 Grunting respiration SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62085005 An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. (MSH) UMLS:C0011991 Diarrhoea bacterial gastroenteritis fecal incontinence incontinence of feces loose bowel loose bowels the runs SNOMEDCT_US:62315008 Diarrhea SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62315008 UMLS:C0277871 Bovine cough (finding) SNOMEDCT_US:62427007 Bovine cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62427007 UMLS:C0520860 Abnormal jugular venous pressure (finding) SNOMEDCT_US:62436006 Abnormal jugular venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62436006 UMLS:C0004770 Bartonella species Genus Bartonella Genus Bartonella (organism) Grahamella Rochalimea SNOMEDCT_US:62496009 Bartonella SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62496009 UMLS:C0231912 Nocturnal cough (finding) SNOMEDCT_US:62548007 Nocturnal cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62548007 UMLS:C0231913 Early morning cough (finding) SNOMEDCT_US:62618004 Early morning cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62618004 UMLS:C0425544 Fine respiratory crackles (finding) Fine respiratory crepitations SNOMEDCT_US:62640008 Fine respiratory crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62640008 UMLS:C0153134 Congenital syphilitic meningitis (disorder) Meningitis due to congenital syphilis SNOMEDCT_US:6267005 Congenital syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:6267005 UMLS:C0574067 Increasing frequency of cough (finding) SNOMEDCT_US:62731002 Increasing frequency of cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:62731002 UMLS:C0277870 Spasmodic cough (finding) SNOMEDCT_US:63000007 Spasmodic cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:63000007 UMLS:C0234058 Sexual exhaustion (finding) SNOMEDCT_US:63195009 Sexual exhaustion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:63195009 UMLS:C0231880 Superficial crackling rales (finding) SNOMEDCT_US:63642005 Superficial crackling rales SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:63642005 UMLS:C0232598 Chronic vomiting (disorder) SNOMEDCT_US:63722008 Chronic vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:63722008 UMLS:C0519030 Pneumonia caused by Klebsiella pneumoniae Pneumonia caused by Klebsiella pneumoniae (disorder) SNOMEDCT_US:64479007 Pneumonia due to Klebsiella pneumoniae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:64479007 UMLS:C0206061 Interstitial pneumonia (disorder) Interstitial pneumonitis SNOMEDCT_US:64667001 Interstitial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:64667001 UMLS:C0264379 Terminal bronchopneumonia (disorder) SNOMEDCT_US:64703005 Terminal bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:64703005 UMLS:C0276332 Parainfluenza bronchopneumonia Parainfluenza virus bronchopneumonia (disorder) SNOMEDCT_US:64880000 Parainfluenza virus bronchopneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:64880000 UMLS:C0276333 Parainfluenza pneumonia Parainfluenza virus pneumonia (disorder) Parainfluenzal pneumonia Pneumonia due to parainfluenza virus SNOMEDCT_US:64917006 Parainfluenza virus pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:64917006 UMLS:C0152502 Amoebic lung abscess SNOMEDCT_US:65095005 Amebic lung abscess SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:65095005 UMLS:C0264386 Foreign body pneumonia (disorder) SNOMEDCT_US:65141002 Foreign body pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:65141002 UMLS:C0315265 Klebsiella ozaenae Klebsiella pneumoniae ss. ozaenae (organism) Klebsiella pneumoniae subsp ozaenae SNOMEDCT_US:65186004 Klebsiella pneumoniae ss. ozaenae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:65186004 Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock. (NCI) UMLS:C0264490 Acute respiratory failure (disorder) SNOMEDCT_US:65710008 Acute respiratory failure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:65710008 UMLS:C0023355 Leptomeningitis (disorder) SNOMEDCT_US:66074005 Leptomeningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:66074005 UMLS:C0264382 Unresolved lobar pneumonia (disorder) SNOMEDCT_US:66429007 Unresolved lobar pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:66429007 UMLS:C0318202 Genus Succinivibrio Genus Succinivibrio (organism) Succinivibrio species SNOMEDCT_US:66866005 Succinivibrio SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:66866005 A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. (NCI) UMLS:C0035222 ARDS - Adult respiratory distress syndrome Acute respiratory distress syndrome (disorder) Adult hyaline membrane disease Adult respiratory distress syndrome Congestive atelectasis DaNang lung Post-traumatic pulmonary insufficiency Pulmonary capillary leak syndrome Shock lung Traumatic wet lung Vietnam lung SNOMEDCT:67782005 Acute respiratory distress syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT:67782005 UMLS:C0278141 SNOMEDCT_US:67849003 Excruciating pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:67849003 UMLS:C0010201 SNOMEDCT_US:68154008 Chronic cough SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:68154008 UMLS:C0264383 Organised pneumonia Organized pneumonia (disorder) SNOMEDCT_US:68409003 Organized pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:68409003 UMLS:C0232110 Abnormal arterial pulse pressure (finding) SNOMEDCT_US:68603007 Abnormal arterial pulse pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:68603007 Diagnostic procedures involving immunoglobulin reactions. (MSH) UMLS:C0036743 SNOMEDCT_US:68793005 Serological test SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:68793005 UMLS:C0275839 Acute syphilitic meningitis (disorder) SNOMEDCT_US:68863007 Acute syphilitic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:68863007 UMLS:C0030105 Primary atrophic rhinitis Ozaena Ozena (disorder) Primary atrophic rhinitis Severe chronic rhinitis SNOMEDCT_US:69646003 Ozena SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:69646003 UMLS:C0232115 Increased venous pressure (finding) SNOMEDCT_US:69791001 Increased venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:69791001 UMLS:C3697300 SNOMEDCT_US:698641001 Postoperative aseptic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:698641001 UMLS:C3697592 Postoperative bacterial meningitis (disorder) SNOMEDCT_US:698734003 Postoperative bacterial meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:698734003 UMLS:C0694550 Recurrent pneumonia (disorder) SNOMEDCT_US:699014000 Recurrent pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:699014000 UMLS:C3084169 Class Negativicutes SNOMEDCT_US:115101008 Negativicutes SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:115101008 UMLS:C1800706 Cryptogenic fibrosing alveolitis Idiopathic fibrosing alveolitis Idiopathic pulmonary fibrosis (disorder) Usual interstitial pneumonia SNOMEDCT_US:700250006 Idiopathic pulmonary fibrosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:700250006 UMLS:C3812396 Cryptogenic fibrosing alveolitis CFA - Cryptogenic fibrosing alveolitis Chronic idiopathic pulmonary fibrosis (disorder) SNOMEDCT_US:700251005 Chronic idiopathic pulmonary fibrosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:700251005 UMLS:C3839204 Influenza A virus subtype H10 (organism) SNOMEDCT_US:700349009 Influenza A virus subtype H10 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:700349009 UMLS:C3839394 SNOMEDCT_US:700350009 Influenza A virus subtype H10N8 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:700350009 UMLS:C0276026 Haemophilus influenzae pneumonia (disorder) SNOMEDCT_US:70036007 Haemophilus influenzae pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:70036007 Average of two or more properly measured readings at each of two or more visits after an initial screen with a systolic 120 to 139 mmHg or diastolic 80 to 89 mmHg. (SNOMEDCT_US) UMLS:C1696708 Prehypertension (finding) SNOMEDCT_US:702817009 Prehypertension SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:702817009 UMLS:C1262006 SNOMEDCT_US:703470001 Bacterial sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:703470001 UMLS:C0221236 Chronic interstitial pneumonia (disorder) SNOMEDCT_US:704345008 Chronic interstitial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:704345008 Mental and physical fatigue from prolonged or difficult treatment. (SNOMEDCT_US) UMLS:C3875100 Exhaustion from treatment Fatigue due to treatment (finding) SNOMEDCT_US:704369007 Fatigue due to treatment SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:704369007 UMLS:C0264515 Gangrenous pneumonia (disorder) Necrotic pneumonia Necrotising pneumonia Necrotizing pneumonia SNOMEDCT_US:7063008 Gangrenous pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7063008 UMLS:C0277895 Abnormal central venous pressure (finding) SNOMEDCT_US:70679005 Abnormal central venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:70679005 Congenital or functional absence of spleen. (SNOMEDCT_US) UMLS:C0600031 Asplenia (disorder) SNOMEDCT_US:707147002 Asplenia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707147002 UMLS:C3873438 Post exercise systolic blood pressure response normal (finding) SNOMEDCT_US:707304009 Post exercise systolic blood pressure response normal SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707304009 UMLS:C0032298 Exogenous lipoid pneumonia (disorder) SNOMEDCT_US:707449006 Exogenous lipoid pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707449006 UMLS:C3873307 Pneumonia caused by Schistosoma mansoni Pneumonia caused by Schistosoma mansoni (disorder) SNOMEDCT_US:707503004 Pneumonia due to Schistosoma mansoni SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707503004 UMLS:C3873305 Pneumonia caused by Schistosoma japonicum Pneumonia caused by Schistosoma japonicum (disorder) Pneumonia in schistosomiasis caused by Schistosoma japonicum Pneumonia in schistosomiasis due to Schistosoma japonicum SNOMEDCT_US:707507003 Pneumonia due to Schistosoma japonicum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707507003 UMLS:C3873304 Pneumonia caused by Schistosoma haematobium Pneumonia caused by Schistosoma haematobium (disorder) Pneumonia in schistosomiasis caused by Schistosoma haematobium Pneumonia in schistosomiasis due to Schistosoma haematobium SNOMEDCT_US:707508008 Pneumonia due to Schistosoma haematobium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:707508008 UMLS:C3872845 Idiopathic eosinophilic pneumonia (disorder) SNOMEDCT_US:708031000 Idiopathic eosinophilic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:708031000 A non-invasive method that provides estimates of arterial hemoglobin oxygen saturation by utilizing selected wavelengths of light. (NCI) UMLS:C0034108 SNOMEDCT_US:708065004 Pulse oximetry SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:708065004 UMLS:C3872584 Systolic blood pressure of neonate at birth (observable entity) SNOMEDCT_US:708502007 Systolic blood pressure of neonate at birth SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:708502007 UMLS:C3872655 Diastolic blood pressure of neonate at birth (observable entity) SNOMEDCT_US:708507001 Diastolic blood pressure of neonate at birth SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:708507001 UMLS:C3872571 SNOMEDCT_US:708527000 Influenza A virus subtype H5N8 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:708527000 UMLS:C0521519 Acute muscle stiffness of neck (finding) SNOMEDCT_US:710134003 Acute muscle stiffness of neck SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:710134003 UMLS:C0445933 Anaerobic Campylobacter species (organism) SNOMEDCT_US:710331003 Anaerobic Campylobacter species SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:710331003 UMLS:C4039458 Anaerobic Staphylococcus species (organism) SNOMEDCT_US:710335007 Anaerobic Staphylococcus species SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:710335007 UMLS:C3542020 Hypothermia not associated with low environmental temperature (finding) SNOMEDCT_US: 123461000119109 Hypothermia not associated with low environmental temperature SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 123461000119109 An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions. (MSH) UMLS:C0025309 Meningoencephalitis (disorder) SNOMEDCT_US:7125002 Meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7125002 UMLS:C4075701 Pneumonia caused by Human coronavirus (disorder) SNOMEDCT_US:713084008 Pneumonia caused by Human coronavirus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713084008 UMLS:C0747667 Recurrent bacterial pneumonia (disorder) SNOMEDCT_US:713525001 Recurrent bacterial pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713525001 UMLS:C4076039 Recurrent bacterial pneumonia co-occurrent with human immunodeficiency virus infection (disorder) SNOMEDCT_US:713526000 Recurrent bacterial pneumonia co-occurrent with human immunodeficiency virus infection SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713526000 UMLS:C4076007 Bacterial pneumonia co-occurrent with human immunodeficiency virus infection (disorder) SNOMEDCT_US:713544008 Bacterial pneumonia co-occurrent with human immunodeficiency virus infection SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713544008 UMLS:C4075878 Meningitis caused by Histoplasma capsulatum (disorder) SNOMEDCT_US:713624009 Meningitis caused by Histoplasma capsulatum SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713624009 UMLS:C0276674 Meningitis caused by Histoplasma duboisii (disorder) SNOMEDCT_US:713625005 Meningitis caused by Histoplasma duboisii SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713625005 UMLS:C4075890 Meningitis caused by Histoplasmosis (disorder) SNOMEDCT_US:713626006 Meningitis caused by Histoplasmosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:713626006 UMLS:C0270256 Hypothermia of newborn (disorder) SNOMEDCT_US:13629008 Hypothermia of newborn SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:13629008 UMLS:C0232599 Bilious emesis Bilious vomiting (disorder) Vomiting bile SNOMEDCT_US:71419002 Bilious vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:71419002 The blood pressure in the central large VEINS of the body. It is distinguished from peripheral venous pressure which occurs in an extremity. (MSH) UMLS:C0428640 CVP - Central venous pressure Central venous pressure (observable entity) SNOMEDCT_US:71420008 Central venous pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:71420008 UMLS:C0231914 SNOMEDCT_US:7142008 Cough at rest SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7142008 UMLS:C4275186 Influenza A virus, not subtype H1N1 (organism) SNOMEDCT_US:715333003 Influenza A virus, not subtype H1N1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715333003 MSH | A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 7 and neuraminidase 7. The H7N7 subtype produced an epidemic in 2003 which was highly pathogenic among domestic birds (POULTRY). Some infections in humans were reported. UMLS:C1612845 SNOMEDCT_US:715346008 Influenza A virus subtype H7N7 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715346008 MSH | A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 7 and neuraminidase 3. It was first detected in turkeys in Britain in 1963 and there have been several outbreaks on poultry farms since that time. A couple cases of human infections have been reported. UMLS:C2936288 SNOMEDCT_US:715347004 Influenza A virus subtype H7N3 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715347004 UMLS:C2936282 SNOMEDCT_US:715348009 Influenza A virus subtype H7N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715348009 UMLS:C1620282 SNOMEDCT_US:715349001 Influenza A virus subtype H2N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715349001 UMLS:C2936289 SNOMEDCT_US:715350001 Influenza A virus subtype H10N7 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715350001 Perceptions of Stuttering Inventory score Perceptions of Stuttering Inventory score (observable entity) SNOMEDCT_US:715813006 PSI (Perceptions of Stuttering Inventory) score SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715813006 UMLS:C4274965 Influenza A virus, not subtype H1 and not subtype H3 (organism) SNOMEDCT_US:715870001 Influenza A virus, not subtype H1 and not subtype H3 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:715870001 UMLS:C4274438 Baseline systolic blood pressure (observable entity) SNOMEDCT_US:716579001 Baseline systolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:716579001 UMLS:C4274392 Baseline diastolic blood pressure (observable entity) SNOMEDCT_US:716632005 Baseline diastolic blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:716632005 Fatigue associated with malignant neoplastic disease SNOMEDCT_US:716749005 Cancer-related fatigue SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:716749005 Inflammation of the meninges (three thin layers of tissue that cover and protect the brain and spinal cord). Meningitis is usually caused by a bacterial or viral infection, but sometimes is caused by cancer, drug allergies, or inflammatory diseases. (NCI) Meningitis is a nervous system symptom characterized as an inflammation of the meninges and especially of the pia mater and the arachnoid. (SYMP) HP:0001287 MSH:D008581 SYMP:0019173 UMLS:C0025289 Meningitis (disorder) SNOMEDCT_US:7180009 Meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7180009 UMLS:C0232286 Precordial pain (finding) SNOMEDCT_US:71884009 Precordial pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:71884009 UMLS:C0270151 Congenital infective pneumonia Fetal pneumonia Foetal pneumonia Infective pneumonia acquired prenatally (disorder) Intrauterine pneumonia SNOMEDCT_US:71926009 Infective pneumonia acquired prenatally SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:71926009 UMLS:C0001973 Alcohol problem drinking Alcoholism (disorder) Dipsomania SNOMEDCT_US:7200002 Alcoholism SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7200002 UMLS:C2887054 Anthrax meningitis Meningitis due to anthrax SNOMEDCT_US:720990007 Meningitis caused by Bacillus anthracis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:720990007 UMLS:C4303471 Aerobic gram-negative coccus meningitis SNOMEDCT_US:721240006 Meningitis caused by gram-negative aerobic coccus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721240006 UMLS:C4303470 Aerobic gram-negative bacillus meningitis SNOMEDCT_US:721241005 Meningitis caused by gram-negative aerobic bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721241005 UMLS:C4303077 Meningitis caused by Spirochaetes (disorder) SNOMEDCT_US:721242003 Meningitis caused by Spirochaetes SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721242003 UMLS:C0154653 Chronic meningitis (disorder) SNOMEDCT_US:21664006 Chronic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:21664006 UMLS:C4303156 Enterobacter meningitis Meningitis caused by Enterobacter (disorder) SNOMEDCT_US:721729004 Meningitis caused by Enterobacter SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721729004 UMLS:C4303148 Meningitis caused by Streptococcus agalactiae (disorder) SNOMEDCT_US:721746001 Meningitis caused by Streptococcus agalactiae SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721746001 UMLS:C4303146 Meningitis caused by Enterococcus (disorder) SNOMEDCT_US:721748000 Meningitis caused by Enterococcus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721748000 UMLS:C4303145 Meningitis caused by methicillin resistant Staphylococcus aureus (disorder) SNOMEDCT_US:721749008 Meningitis caused by methicillin resistant Staphylococcus aureus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721749008 UMLS:C4303143 Actinomycetales meningitis SNOMEDCT_US:721752000 Meningitis caused by Actinomycetales SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721752000 UMLS:C4303142 Meningitis due to Nocardia species SNOMEDCT_US:721753005 Meningitis caused by Nocardia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721753005 UMLS:C0041318 Tropheryma whipplei meningitis SNOMEDCT_US:721754004 Meningitis caused by Tropheryma whipplei SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721754004 UMLS:C4303114 Meningitis due to Mucormycosis Meningitis due to Mucormycosis (disorder) SNOMEDCT_US:721792003 Meningitis caused by Mucorales SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721792003 UMLS:C4303090 Meningitis caused by Taenia solium (disorder) Meningitis due to cysticercosis SNOMEDCT_US:721824003 Meningitis caused by Taenia solium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721824003 UMLS:C0520905 Postoperative vomiting (disorder) SNOMEDCT_US:72245005 Postoperative vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:72245005 UMLS:C4302377 Meningitis following procedure (disorder) Post-procedural meningitis SNOMEDCT_US:722658006 Meningitis following procedure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:722658006 UMLS:C2712362 Bilious vomiting of newborn (disorder) SNOMEDCT_US:722933003 Bilious vomiting of newborn SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:722933003 UMLS:C0338389 Chronic echovirus meningoencephalitis (disorder) SNOMEDCT_US:230144003 Chronic echovirus meningoencephalitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230144003 UMLS:C0393442 Non-infective meningitis (disorder) SNOMEDCT_US:230155003 Non-infective meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:230155003 UMLS:C0871470 Systolic arterial pressure (observable entity) SNOMEDCT_US:72313002 Systolic arterial pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:72313002 UMLS:C4518469 Idiopathic acute eosinophilic pneumonia (disorder) SNOMEDCT_US:724499007 Idiopathic acute eosinophilic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:724499007 UMLS:C2930941 Idiopathic chronic eosinophilic pneumonia (disorder) SNOMEDCT_US:724500003 Idiopathic chronic eosinophilic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:724500003 UMLS:C4510716 Neck pain co-occurrent with neck stiffness following whiplash injury to neck (disorder) SNOMEDCT_US:725009002 Neck pain co-occurrent with neck stiffness following whiplash injury to neck SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:725009002 UMLS:C4511382 Neck pain co-occurrent with neurological deficit following whiplash injury to neck (disorder) SNOMEDCT_US:725011006 Neck pain co-occurrent with neurological deficit following whiplash injury to neck SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:725011006 UMLS:C0264384 Granulomatous pneumonia (disorder) SNOMEDCT_US:72656004 Granulomatous pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:72656004 UMLS:C0582606 Hypothermia caused by anesthetic (finding) SNOMEDCT_US: 269287005 Hypothermia caused by anesthetic SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 269287005 UMLS:C0456107 Neonatal meningitis (disorder) SNOMEDCT_US:276674008 Neonatal meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:276674008 UMLS:C0314771 Acetivibrio species Genus Acetivibrio Genus Acetivibrio (organism) SNOMEDCT_US:72806006 Acetivibrio SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:72806006 UMLS:C4303100 Meningitis caused by Trypanosoma brucei (disorder) Meningitis due to African trypanosomiasis SNOMEDCT_US:721814006 Meningitis caused by Trypanosoma brucei SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:721814006 UMLS:C0264391 Aspiration pneumonia due to near drowning (disorder) SNOMEDCT_US:72854003 Aspiration pneumonia due to near drowning SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:72854003 A disease in which the body does not control the amount of glucose (a type of sugar) in the blood and the kidneys make a large amount of urine. This disease occurs when the body does not make enough insulin or does not use it the way it should. (NCI) UMLS:C0011849 DM - Diabetes mellitus Diabetes mellitus (disorder) SNOMEDCT_US:73211009 Diabetes mellitus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:73211009 UMLS:C4518562 Gram positive pneumonia Pneumonia caused by Gram positive bacteria (disorder) SNOMEDCT_US:733051000 Pneumonia caused by Gram positive bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:733051000 UMLS:C4518626 Eosinophilic meningitis caused by Angiostrongylus cantonensis SNOMEDCT_US:733173009 Eosinophilic meningitis due to Angiostrongylus cantonensis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:733173009 UMLS:C4542873 Filamentous gram-negative bacillus (organism) Filamentous gram-negative rod SNOMEDCT_US:734291004 Filamentous gram-negative bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:734291004 A bacterial, fungal or parasitic abscess that develops in the lung parenchyma. Causes include aspiration pneumonia, necrotizing pneumonia, necrotizing malignant tumors, and Wegener's granulomatosis. (NCI) Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents. (MSH) HP:0025044 UMLS:C0024110 Abscess of lung (disorder) Lung abscess SNOMEDCT_US:73452002 Abscess of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:73452002 UMLS:C0314753 Gram-negative pleomorphic bacillus (organism) SNOMEDCT_US:73460001 Gram-negative pleomorphic bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:73460001 C0332207 SNOMEDCT_US:73681006 Acinar SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:73681006 Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries. (MSH) Induced hypothermia (finding) SNOMEDCT_US: 398052002 Induced hypothermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 398052002 UMLS:C0025311 Meningomyelitis (disorder) SNOMEDCT_US:74772000 Meningomyelitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:74772000 UMLS:C0577961 Inspiratory crackles (finding) SNOMEDCT_US:75252003 Inspiratory crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:75252003 The pressure of the circulating blood against the walls of the blood vessels. (NCI) SNOMEDCT_US:75367002 UMLS:C0005823 BP - Blood pressure Blood pressure (observable entity) SNOMEDCT_US:75367002 Blood pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:75367002 UMLS:C0264387 Aspiration pneumonia caused by regurgitated food Aspiration pneumonia caused by regurgitated food (disorder) SNOMEDCT_US:75426006 Aspiration pneumonia due to regurgitated food SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:75426006 UMLS:C0152450 Rheumatic pneumonia (disorder) Rheumatic pneumonitis SNOMEDCT_US:7548000 Rheumatic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7548000 A respiratory disorder characterized by higher than normal respiratory rates among premature and cesarean section delivered neonates whose lungs have not fully matured. The cause is often excess fluid in the lungs, and resolution is aided by supplemental oxygen and sometimes, antibiotics. (NCI) Abnormal increase in RESPIRATORY RATE in the newborn. It is self-limiting and attributed to the delayed fetal lung fluid clearance often in CAESAREAN SECTION delivery. (MSH) UMLS:C0158940 Idiopathic tachypnea of newborn Idiopathic tachypnoea of newborn Newborn transitory tachypnea Newborn transitory tachypnoea TTN - Transient tachypnea of newborn TTN - Transient tachypnoea of newborn Tachypnea resolving about 6 hours postnatally Tachypnoea resolving about 6 hours postnatally Transient tachypnea of newborn Transient tachypnoea of newborn Transitory tachypnea of newborn (disorder) Transitory tachypnoea of newborn Wet lung syndrome in newborn SNOMEDCT_US:7550008 Transitory tachypnea of newborn SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7550008 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus. (DOID) UMLS:C0032310 SNOMEDCT_US:75570004 Viral pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:75570004 A congenital (due to inherited enzyme abnormality) or acquired (due to failure of a metabolic important organ) disorder resulting from an abnormal metabolic process. (NCI) UMLS:C0025517 MD - Metabolic disorders Metabolic disease (disorder) Metabolic disorder SNOMEDCT_US:75934005 Metabolic disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:75934005 UMLS:C4545991 Hypertrophic pachymeningitis due to infection (disorder) Pachymeningitis secondary to infection SNOMEDCT_US:762281000 Hypertrophic pachymeningitis due to infection SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:762281000 UMLS:C4546000 Unplanned perioperative hypothermia (disorder) SNOMEDCT_US: 762680008 Unplanned perioperative hypothermia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 762680008 UMLS:C4707447 Vomiting co-occurrent and due to infectious disease (disorder) SNOMEDCT_US:765480005 Vomiting co-occurrent and due to infectious disease SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:765480005 A state of acute circulatory failure characterized by persistent arterial hypotension despite adequate fluid resuscitation or by tissue hypoperfusion unexplained by other causes. (NCI)(NCI) UMLS:C0036983 Sepsis-associated hypotension Septic shock (disorder) Septicaemic shock Septicemic shock SNOMEDCT_US:76571007 Septic shock SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:76571007 UMLS:C0276253 Cytomegalic inclusion virus pneumonia Cytomegaloviral (CMV) pneumonia Cytomegaloviral pneumonia (disorder) Cytomegaloviral pneumonitis SNOMEDCT_US:7678002 Cytomegaloviral pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:7678002 UMLS:C4708768 No cough strength (finding) SNOMEDCT_US:769211009 No cough strength SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:769211009 UMLS:C0278140 Intense pain SNOMEDCT_US:76948002 Severe pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:76948002 UMLS:C3696960 Post-traumatic meningitis Posttraumatic meningitis (disorder) SNOMEDCT_US:698782009 Posttraumatic meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:698782009 UMLS:C4518428 Neck pain co-occurrent with tenderness of neck following whiplash injury to neck SNOMEDCT:725009002 Neck pain co-occurrent with tenderness of neck following whiplash injury to neck SNOMEDCT_US: 2021/01/06 SNOMEDCT:725009002 UMLS:C1614502 SNOMEDCT_US:772807005 Influenza A virus subtype H3N8 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:772807005 UMLS:C2718048 SNOMEDCT_US:772809008 Influenza A virus subtype H1N2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:772809008 UMLS:C1613950 SNOMEDCT_US:772827006 Influenza A virus subtype H5N1 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:772827006 UMLS:C0314760 Coliform Coliform bacteria (organism) SNOMEDCT_US:77309002 Coliform bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:77309002 UMLS:C0155800 Chronic hypotension (disorder) Permanent idiopathic hypotension SNOMEDCT_US:77545000 Chronic hypotension SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:77545000 UMLS:C0152488 Meningitis due to salmonella SNOMEDCT_US:77645007 Salmonella meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:77645007 Washing out the bronchi and alveoli by flushing with a fluid. (NCI) UMLS:C1535502 Bronchioloalveolar lavage Bronchoalveolar lavage (procedure) SNOMEDCT_US:782971002 Bronchoalveolar lavage SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:782971002 UMLS:C5191288 Fatigue due to chemotherapy (finding) SNOMEDCT_US:784317004 Fatigue due to chemotherapy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:784317004 UMLS:C5191289 Fatigue due to radiation therapy (finding) SNOMEDCT_US:784318009 Fatigue due to radiation therapy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:784318009 A rare genetic familial partial epilepsy disease with characteristics of simple partial seizures, complex partial seizures and/or secondarily generalized seizures, originating from the inner aspect of the temporal lobe, associated with an antecedent history of febrile seizures, occurring in various members of a family. Hippocampal abnormalities (for example hippocampal sclerosis) may also be associated. There is evidence the disease is caused by homozygous mutation in the CPA6 gene on chromosome 8q13. UMLS:C5191318 Familial mesial temporal lobe epilepsy with febrile seizures (disorder) SNOMEDCT:230432008 Familial mesial temporal lobe epilepsy with febrile seizures SNOMEDCT_US: 2021/01/06 SNOMEDCT:230432008 The rhythmic wave within the arteries occurring with each contraction of the left ventricle. (NCI) UMLS:C0232117 Heart rate measured at systemic artery SNOMEDCT_US:78564009 Pulse rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:78564009 The removal of a small piece of lung tissue to be checked by a pathologist for cancer or other diseases. The tissue may be removed using a bronchoscope (a thin, lighted, tube-like instrument that is inserted through the trachea and into the lung). It may also be removed using a fine needle inserted through the chest wall, by surgery guided by a video camera inserted through the chest wall, or by an open biopsy. In an open biopsy, a doctor makes an incision between the ribs, removes a sample of lung tissue, and closes the wound with stitches. (NCI) UMLS:C0189485 Biopsy of lung (procedure) SNOMEDCT_US:78603008 Biopsy of lung SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:78603008 An acute or chronic inflammatory process affecting the mucous membrane of the frontal sinus. (NCI) inflammation of the NASAL MUCOSA in the FRONTAL SINUS. In many cases, it is caused by an infection of the bacteria STREPTOCOCCUS PNEUMONIAE or HAEMOPHILUS INFLUENZAE. (MSH) UMLS:C0016735 SNOMEDCT_US:78737005 Frontal sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:78737005 UMLS:C0158935 Congenital pneumonia (disorder) SNOMEDCT_US:78895009 Congenital pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:78895009 UMLS:C5230587 Acute exacerbation of idiopathic pulmonary fibrosis (disorder) SNOMEDCT_US:789574002 Acute exacerbation of idiopathic pulmonary fibrosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:789574002 UMLS:C0018150 Gram-negative bacterium (organism) SNOMEDCT_US:81325006 Gram-negative bacterium SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:81325006 UMLS:C0232288 Chest pain on exertion (finding) SNOMEDCT_US:81953000 Chest pain on exertion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:81953000 UMLS:C0333659 SNOMEDCT_US:83158003 Exhaustion atrophy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:83158003 UMLS:C0085498 GPB - Gram-positive bacillus Gram-positive bacillus (organism) Gram-positive rod Gram-positive rods SNOMEDCT_US:83514008 Gram-positive bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:83514008 UMLS:C1405205 Aspiration pneumonia caused by inhalation of milk SNOMEDCT_US:83608006 Aspiration pneumonia due to inhalation of milk SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:83608006 UMLS:C0270618 Chronic adhesive pachymeningitis (disorder) SNOMEDCT_US:84306007 Chronic adhesive pachymeningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:84306007 UMLS:C0276644 Pneumonia in systemic mycosis (disorder) SNOMEDCT_US:84753008 Pneumonia in systemic mycosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:84753008 UMLS:C0332581 Local cyanosis (finding) SNOMEDCT_US:84906002 Local cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:84906002 UMLS:C0425547 Post-tussive crackles (finding) Post-tussive crepitations Post-tussive rales SNOMEDCT_US:85377008 Post-tussive crackles SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:85377008 UMLS:C0264522 Hypostatic pneumonia (disorder) Passive pneumonia SNOMEDCT_US:85469005 Hypostatic pneumonia SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:85469005 Forceful expulsion of the contents of the stomach through the mouth. (NCI) HP:0002587 UMLS:C0221151 SNOMEDCT_US:8579004 Projectile vomiting SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:8579004 UMLS:C0318086 Genus Selenomonas Genus Selenomonas (organism) Selenomonas species SNOMEDCT_US:85986007 Selenomonas SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:85986007 UMLS:C0264270 SNOMEDCT_US:86287004 Hypertrophic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:86287004 The number of times an organism breathes with the lungs (RESPIRATION) per unit time, usually per minute. (MSH) UMLS:C0231832 RR - Respiratory rate SNOMEDCT_US:86290005 Respiratory rate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:86290005 UMLS:C4543700 SNOMEDCT_US:8691000175105 Multilobar lung infiltrate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:8691000175105 UMLS:C4543701 Single lobe lung infiltrate (disorder) SNOMEDCT_US:8701000175105 Single lobe lung infiltrate SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:8701000175105 UMLS:C0314752 Gram-negative bacillus (organism) Gram-negative rods SNOMEDCT_US:87172008 Gram-negative bacillus SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:87172008 UMLS:C0018154 Gram-positive bacterium Gram-positive bacterium (organism) SNOMEDCT_US:8745002 Gram-positive bacteria SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:8745002 Vomiting blood. (NCI) HP:0002248 SYMP:0019147 UMLS:C0018926 Haematemesis Hematemesis (disorder) Vomiting blood Vomiting of blood SNOMEDCT_US:8765009 Hematemesis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:8765009 UMLS:C0161749 SNOMEDCT_US:88164008 Exhaustion due to exposure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:88164008 UMLS:C5244027 COVID-19 pneumonia Pneumonia caused by 2019 novel coronavirus Pneumonia caused by 2019-nCoV Pneumonia caused by Severe acute respiratory syndrome coronavirus 2 Pneumonia caused by Severe acute respiratory syndrome coronavirus 2 (disorder) SNOMEDCT_US:882784691000119100 Pneumonia caused by SARS-CoV-2 SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:882784691000119100 UMLS:C0024959 SNOMEDCT_US:88348008 Maxillary sinusitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:88348008 UMLS:C0413296 Postimmersion syndrome Postimmersion-submersion syndrome (disorder) Secondary drowning SNOMEDCT:89687005 Postimmersion-submersion syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT:89687005 Physical and psychological dependence on nicotine. (NCI) UMLS:C1306274 Compulsive tobacco user syndrome Tabagism Tobacco abuse Tobacco dependence Tobacco dependence syndrome (disorder) SNOMEDCT_US:89765005 Tobacco dependence syndrome SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:89765005 UMLS:C0520849 Normal arterial wedge pressure Normal pulmonary arterial wedge pressure (finding) Normal pulmonary capillary wedge pressure SNOMEDCT_US:301140001 Normal pulmonary arterial wedge pressure SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:301140001 UMLS:C0275905 Tuberculosis of cerebral meninges (disorder) SNOMEDCT_US:90302003 Tuberculosis of cerebral meninges SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:90302003 UMLS:C0269661 Vomiting as reason for care in pregnancy SNOMEDCT_US:90325002 Vomiting of pregnancy SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:90325002 Aspiration of fluid or air from the THORACIC CAVITY. It is coupled sometimes with the administration of drugs into the PLEURAL CAVITY. (MSH) The removal of excess fluid via needle puncture from the thoracic cavity. (NCI) UMLS:C0189477 Chest aspiration Pleural aspiration Pleural cavity tap Pleural tap Pleurocentesis Thoracentesis (procedure) Thoracic paracentesis Thoracocentesis SNOMEDCT_US:91602002 Thoracentesis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:91602002 UMLS:C0392685 Chest pain at rest (finding) SNOMEDCT_US:9267009 Chest pain at rest SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:9267009 UMLS:C0275729 Bull nose Bull nose Necrotic rhinitis (disorder) SNOMEDCT_US:9312005 Necrotic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:9312005 UMLS:C0684902 SNOMEDCT_US: 93447004 Eosinophilic nonallergic rhinitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US: 93447004 UMLS:C0149980 Nasal spray syndrome SNOMEDCT_US:95239003 Rhinitis medicamentosa SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95239003 UMLS:C0339800 Rhinitis sicca (disorder) SNOMEDCT_US:95240001 Rhinitis sicca SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95240001 UMLS:C0235532 Peripheral cyanosis (finding) SNOMEDCT_US:95442007 Peripheral cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95442007 UMLS:C0332581 Neonatal cyanosis (disorder) SNOMEDCT_US:95617006 Neonatal cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95617006 A form of cyanosis that occurs when there is a decrease in oxygen saturation in the arterial blood, usually with an SaO2 of below 75% UMLS:C0521800 Central cyanosis (disorder) SNOMEDCT_US:95837007 Central cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95837007 UMLS:C0521801 Pulmonary cyanosis (disorder) SNOMEDCT_US:95838002 Pulmonary cyanosis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95838002 A clinical syndrome caused by heat stress, such as over-exertion in a hot environment or excessive exposure to sun. It is characterized by SWEATING, water (volume) depletion, salt depletion, cool clammy skin, NAUSEA, and HEADACHE. (MSH) UMLS:C0018839 Heat exhaustion (disorder) Heat prostration SNOMEDCT_US:95868006 Heat exhaustion SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95868006 UMLS:C0085437 BM - Bacterial meningitis Bacterial meningitis (disorder) Meningitis, bacterial SNOMEDCT_US:95883001 Bacterial meningitis SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:95883001 UMLS:C2184182 Localised chest pain Localized chest pain (finding) SNOMEDCT_US:97001000119106 Localized chest pain SNOMEDCT_US: 2021/01/06 SNOMEDCT_US:97001000119106 BFO:0000001 entity Entity Julius Caesar Verdi’s Requiem the Second World War your body mass index BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81 Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) entity Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf per discussion with Barry Smith An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001]) BFO:0000002 continuant Continuant BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240 Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] continuant Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002]) if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001]) if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002]) if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002]) (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] BFO:0000003 occurrent Occurrent BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players. Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] occurrent Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process. per discussion with Barry Smith Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame. An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002]) Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001]) b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001]) (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] BFO:0000004 ic IndependentContinuant a chair a heart a leg a molecule a spatial region an atom an orchestra. an organism the bottom right portion of a human torso the interior of your mouth b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] independent continuant b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001]) For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002]) (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] BFO:0000006 s-region SpatialRegion BFO 2 Reference: Spatial regions do not participate in processes. Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] spatial region Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional. per discussion with Barry Smith A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001]) All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001]) (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] BFO:0000008 t-region TemporalRegion Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] temporal region Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional per discussion with Barry Smith A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001]) All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001]) Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002]) (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] BFO:0000009 2d-s-region TwoDimensionalSpatialRegion an infinitely thin plane in space. the surface of a sphere-shaped part of space A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] two-dimensional spatial region A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001]) (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] BFO:0000011 st-region SpatiotemporalRegion the spatiotemporal region occupied by a human life the spatiotemporal region occupied by a process of cellular meiosis. the spatiotemporal region occupied by the development of a cancer tumor A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) Every spatiotemporal region occupies_spatiotemporal_region itself. Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] spatiotemporal region A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001]) All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001]) Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001]) Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001]) Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002]) (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] BFO:0000015 process Process a process of cell-division, \ a beating of the heart a process of meiosis a process of sleeping the course of a disease the flight of a bird the life of an organism your process of aging. p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] process p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] BFO:0000016 disposition Disposition an atom of element X has the disposition to decay to an atom of element Y certain people have a predisposition to colon cancer children are innately disposed to categorize objects in certain ways. the cell wall is disposed to filter chemicals in endocytosis and exocytosis BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type. b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] disposition b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002]) If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002]) (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] BFO:0000017 realizable RealizableEntity the disposition of this piece of metal to conduct electricity. the disposition of your blood to coagulate the function of your reproductive organs the role of being a doctor the role of this boundary to delineate where Utah and Colorado meet To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] realizable entity To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002]) All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002]) (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] BFO:0000018 0d-s-region ZeroDimensionalSpatialRegion A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] zero-dimensional spatial region A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001]) (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] BFO:0000019 quality Quality the ambient temperature of this portion of air the color of a tomato the length of the circumference of your waist the mass of this piece of gold. the shape of your nose the shape of your nostril a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] quality a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001]) If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001]) (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] BFO:0000020 sdc SpecificallyDependentContinuant Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key of one-sided specifically dependent continuants: the mass of this tomato of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates. the disposition of this fish to decay the function of this heart: to pump blood the mutual dependence of proton donors and acceptors in chemical reactions [79 the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction the pink color of a medium rare piece of grilled filet mignon at its center the role of being a doctor the shape of this hole. the smell of this portion of mozzarella b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] specifically dependent continuant b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc. per discussion with Barry Smith (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] BFO:0000023 role Role John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. the priest role the role of a boundary to demarcate two neighboring administrative territories the role of a building in serving as a military target the role of a stone in marking a property boundary the role of subject in a clinical trial the student role BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives. b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] role b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001]) (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] BFO:0000024 fiat-object-part FiatObjectPart or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29 the FMA:regional parts of an intact human body. the Western hemisphere of the Earth the division of the brain into regions the division of the planet into hemispheres the dorsal and ventral surfaces of the body the upper and lower lobes of the left lung BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] fiat object part b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004]) (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] BFO:0000026 1d-s-region OneDimensionalSpatialRegion an edge of a cube-shaped portion of space. A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] one-dimensional spatial region A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001]) (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] BFO:0000027 object-aggregate ObjectAggregate a collection of cells in a blood biobank. a swarm of bees is an aggregate of members who are linked together through natural bonds a symphony orchestra an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team) defined by fiat: the aggregate of members of an organization defined through physical attachment: the aggregate of atoms in a lump of granite defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container defined via attributive delimitations such as: the patients in this hospital the aggregate of bearings in a constant velocity axle joint the aggregate of blood cells in your body the nitrogen atoms in the atmosphere the restaurants in Palo Alto your collection of Meissen ceramic plates. An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee). ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] object aggregate ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158. b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004]) (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects BFO:0000028 3d-s-region ThreeDimensionalSpatialRegion a cube-shaped region of space a sphere-shaped region of space, A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] three-dimensional spatial region A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001]) (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] BFO:0000029 site Site Manhattan Canyon) a hole in the interior of a portion of cheese a rabbit hole an air traffic control region defined in the airspace above an airport the Grand Canyon the Piazza San Marco the cockpit of an aircraft the hold of a ship the interior of a kangaroo pouch the interior of the trunk of your car the interior of your bedroom the interior of your office the interior of your refrigerator the lumen of your gut your left nostril (a fiat part – the opening – of your left nasal cavity) b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] site b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002]) (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] BFO:0000030 object Object atom cell cells and organisms engineered artifacts grain of sand molecule organelle organism planet solid portions of matter star BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting. BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below). BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47 BFO 2 Reference: an object is a maximal causally unified material entity BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74 b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) object b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001]) BFO:0000031 gdc GenericallyDependentContinuant The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity. the pdf file on your laptop, the pdf file that is a copy thereof on my laptop the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] generically dependent continuant b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] BFO:0000034 function Function the function of a hammer to drive in nails the function of a heart pacemaker to regulate the beating of a heart through electricity the function of amylase in saliva to break down starch into sugar BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc. A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] function A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001]) (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] BFO:0000035 p-boundary ProcessBoundary the boundary between the 2nd and 3rd year of your life. p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] process boundary p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002]) (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] BFO:0000038 1d-t-region OneDimensionalTemporalRegion the temporal region during which a process occurs. BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks). A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] one-dimensional temporal region A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001]) (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] BFO:0000040 material MaterialEntity a flame a forest fire a human being a hurricane a photon a puff of smoke a sea wave a tornado an aggregate of human beings. an energy wave an epidemic the undetached arm of a human being BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60 BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity. BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here. A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] material entity A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002]) Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002]) every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002]) (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] BFO:0000140 cf-boundary ContinuantFiatBoundary b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions. BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29 Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. Every continuant fiat boundary is located at some spatial region at every time at which it exists (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] continuant fiat boundary b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions. (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] BFO:0000141 immaterial ImmaterialEntity BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10 immaterial entity BFO:0000142 1d-cf-boundary OneDimensionalContinuantFiatBoundary The Equator all geopolitical boundaries all lines of latitude and longitude the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin. the median sulcus of your tongue a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] one-dimensional continuant fiat boundary a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001]) (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] BFO:0000144 process-profile ProcessProfile On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance. The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on. b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] process profile b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005]) (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] BFO:0000145 r-quality RelationalQuality John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married. a marriage bond, an instance of requited love, an obligation between one person and another. b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] relational quality b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] BFO:0000146 2d-cf-boundary TwoDimensionalContinuantFiatBoundary a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] two-dimensional continuant fiat boundary a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001]) (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] BFO:0000147 0d-cf-boundary ZeroDimensionalContinuantFiatBoundary the geographic North Pole the point of origin of some spatial coordinate system. the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] zero-dimensional continuant fiat boundary zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona. requested by Melanie Courtot a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001]) (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] BFO:0000148 0d-t-region ZeroDimensionalTemporalRegion a temporal region that is occupied by a process boundary right now the moment at which a child is born the moment at which a finger is detached in an industrial accident the moment of death. temporal instant. A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] zero-dimensional temporal region A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001]) (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] BFO:0000182 history History A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001]) history A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001]) An idiopathic interstitial pneumonia characterized by lung inflammation and scarring that obstructs the small airways and air sacs of the lungs (alveoli). A flu-like illness, with a cough, fever, a feeling of illness (malaise), fatigue, and weight loss, heralds the onset in about 50% of people. Frequent presence of crackling sounds (called Velcro crackles) when the doctor listens with a stethoscope. (DOID) MESH:D018549 UMLS:C0242770 BOOP Cryptogenic organising pneumonitis Cryptogenic organizing pneumonitis bronchiolitis obliterans organising pneumonia bronchiolitis obliterans organizing pneumonia cryptogenic organising pneumonia idiopathic bronchiolitis obliterans with organising pneumonia idiopathic bronchiolitis obliterans with organizing pneumonia DOID:0050157 cryptogenic organizing pneumonia DOID: 2021/01/28 DOID:0050157 OMIM mapping confirmed by DO. [SN]. An idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation. (DOID) MESH:C562470 UMLS:C0238378 RBILD familial desquamative interstitial pneumonitis respiratory bronchiolitis-associated interstitial lung disease DOID:0050158 desquamative interstitial pneumonia DOID: 2021/01/28 DOID:0050158 A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread. (DOID) DOID:0050338 primary bacterial infectious disease DOID: 2021/01/28 DOID:0050338 A bone inflammation disease that has_material_basis_in infection located_in bone or located_in bone marrow. (DOID) An acute or chronic inflammation of the bone and its structures due to infection with pyogenic bacteria. (NCI) HP:0002754 SNOMEDCT_US:60168000 UMLS:C0029443 DOID:1019 osteomyelitis DOID: 2021/01/28 DOID:1019 A disease by infectious agent that results_in infection, has_material_basis_in Bacteria. (DOID) DOID:104 bacterial infectious disease DOID: 2021/01/28 DOID:104 A kidney disease that is characterized by hemolytic anemia, thrombocytopenia, and renal failure caused by platelet thrombi in the microcirculation of the kidney and other organs. (DOID) UMLS:C0019061 haemolytic-uraemic syndrome hemolytic uremic syndrome DOID:12554 hemolytic-uremic syndrome DOID: 2021/01/28 DOID:12554 A respiratory system cancer that is located_in the lung. (DOID) UMLS:C0153492 DOID:1324 lung cancer DOID: 2021/01/28 DOID:1324 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria. (DOID) UMLS:C0032241 inflammation DOID:14319 pleuropneumonia DOID: 2021/01/28 DOID:14319 A disease that is characterized by abnormally rapid cell division. (DOID) cell process disease neoplasm DOID:14566 disease of cellular proliferation DOID: 2021/01/28 DOID:14566 A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. (NCI) UMLS:C0006826 malignancy DOID:162 cancer DOID: 2021/01/28 DOID:162 A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra. (DOID) NCI:C27599 UMLS:C1335051 Non-neoplastic urinary tract disease urinary tract disease DOID:18 urinary system disease DOID: 2021/01/28 DOID:18 A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted by dog tick bite (Dermacentor variabilis), transmitted by deer flies (Chrysops sp) or transmitted by contact with infected animal tissues. (DOID) SNOMEDCT_US_2020_03_01:186298002 UMLS:C0029835 DOID:2123 tularemia DOID: 2021/01/28 DOID:2123 A lung disease that is characterized by narrowing of pulmonary airways. (DOID) UMLS:C0600260 respiratory airway obstruction DOID:2320 obstructive lung disease DOID: 2021/01/28 DOID:2320 A pneumonia located_in the lung parenchyma of unknown cause. (DOID) MESH:D000080203 UMLS:C0085786 Diffuse idiopathic pulmonary fibrosis Idiopathic fibrosing alveolitis DOID:2797 idiopathic interstitial pneumonia DOID: 2021/01/28 DOID:2797 A idiopathic interstitial pneumonia which develops suddenly and is severe. Initially, the lung shows edema, hyaline membranes, and interstitial acute inflammation. Later, it develops loose organizing fibrosis, mostly within alveolar septa and type II pneumocyte hyperplasia. Fever, cough, and difficulty breathing develop over 1 to 2 weeks, typically progressing to acute respiratory failure. (DOID) MESH:D000080203 UMLS:C1279945 AIP Hamman-Rich disease Hamman-Rich syndrome Idiopathic pulmonary fibrosis, acute fatal form accelerated interstitial pneumonia acute interstitial pneumonitis DOID:2800 acute interstitial pneumonia DOID: 2021/01/28 DOID:2800 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. Lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. A dry cough and shortness of breath develop over 6 to 18 months. Low-grade fever and a feeling of illness (malaise) may occur. (DOID) MESH:C562470 UMLS:C1290344 DOID:2801 nonspecific interstitial pneumonia DOID: 2021/01/28 DOID:2801 An obstructive lung disease that is characterized by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. (DOID) MESH:D029424 NCI:C3199 UMLS:C0024117 COLD COPD chronic obstructive airway disease chronic obstructive lung disease DOID:3083 chronic obstructive pulmonary disease DOID: 2021/01/28 DOID:3083 A pneumonia that is defined as an acute lung injury after the inhalation of foreign material such as regurgitated acidic gastric contents, petroleum products and laxative oils. This syndrome occurs in patients who have a marked disturbance of consciousness such as that resulting from a drug overdose, seizures, a massive cerebrovascular accident, or the use of anesthesia. Aspiration of gastric contents results in a chemical burn of the tracheobronchial tree and pulmonary parenchyma, causing an intense parenchymal inflammatory reaction. The disease has_symptom non-productive cough, has_symptom tachypnea, has_symptom bronchospasm, has_symptom bloody sputum, has_symptom frothy sputum, or has_symptom respiratory distress, 2-5 hrs after aspiration. (DOID) UMLS:C0032290 Chemical pneumonitis Mendelson's Syndrome DOID:3240 aspiration pneumonitis DOID: 2021/01/28 DOID:3240 An aspiration pneumonitis resulting from the aspiration of lipids. It is the result of a foreign body-type reaction to the presence of lipid material within the lung parenchyma. It is caused by inhalation of nasal drops with oil base or cosmetic oil and aspiration of mineral oil when used as a laxative agent. (DOID) UMLS:C0032298 Exogenous lipoid pneumonia Lipoid pneumonitis DOID:3241 lipid pneumonia DOID: 2021/01/28 DOID:3241 A bone disease that results_in inflammation of the located_in bone. (DOID) MESH:D010000 SNOMEDCT_US_2020_03_01:274144001 UMLS:C0029400 Inflammatory disorder of bone bone inflammatory disease osteitis DOID:3342 bone inflammation disease DOID: 2021/01/28 DOID:3342 An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (DOID) MESH:D017202 UMLS:C1956346 CHD Coronary disease coronary arteriosclerosis coronary heart disease DOID:3393 coronary artery disease DOID: 2021/01/28 DOID:3393 An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. (DOID) MESH:D011658 NCI:C26869 SNOMEDCT_US_2020_03_01:155613001 UMLS_CUI:C0034069 Fibrosis of lung DOID:3770 pulmonary fibrosis DOID: 2021/01/28 DOID:3770 A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes. (DOID) MESH:D014375 SNOMEDCT_US_2020_03_01:15202009 UMLS:C0041295 DOID:399 tuberculosis DOID: 2021/01/28 DOID:399 A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms. (MSH) MESH:D014511 SNOMEDCT_US_2020_03_01:44730006 UMLS:C0041948 UREMIA OF renal ORIGIN DOID:4676 uremia DOID: 2021/01/28 DOID:4676 A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands. (DOID) UMLS:C0019693 HIV infection DOID:526 human immunodeficiency virus infectious disease DOID: 2021/01/28 DOID:526 A pneumonia that is an acute inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors. It is a sentinel health event (occupational) associated with exposure to ammonia (refrigeration, fertilizer, and oil refining industries), chlorine (alkali and bleach industries), nitrogen oxides (silo fillers, arc welders, and nitric acid industry), sulfur dioxide (paper, refrigeration, and oil refining industries), cadmium (processors and cadmium smelters), trimellitic anhydride (plastics and organic chemical synthesis), and vanadium pentoxide (boilermakers). The two types of pulmonary agents are central and peripheral. Central pulmonary agents, for example, ammonia, are water soluble irritants that injure the upper airways. Peripheral pulmonary agents, for example, phosgene, NOx, and PFIB, are slightly water soluble irritants that injure the alveolar-capillary membranes. Chlorine has both central and peripheral effects. (DOID) UMLS:C0041881 acute chemical pulmonary edema DOID:551 toxic pneumonitis DOID: 2021/01/28 DOID:551 A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (DOID) SNOMEDCT_US:233604007 UMLS:C0032285 acute pneumonia DOID:552 pneumonia DOID: 2021/01/28 DOID:552 A pneumonia in which certain type of white blood cell called an eosinophil accumulates in the lung. These cells cause disruption of the normal air spaces (alveoli) where oxygen is extracted from the atmosphere. It is caused by certain medications or environmental triggers, parasitic infections, and cancer. The most common symptoms include cough, fever, difficulty breathing, and sweating at night. (DOID) MESH:D011657 UMLS:C1527407 Cryptogenic pulmonary eosinophilia DOID:5870 eosinophilic pneumonia DOID: 2021/01/28 DOID:5870 A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS. (DOID) MESH:D000163 SNOMEDCT_US_2020_03_01:62479008 UMLS:C0001175 AIDS acquired immune deficiency acquired immune deficiency syndrome DOID:635 acquired immunodeficiency syndrome DOID: 2021/01/28 DOID:635 A disease of anatomical entity that is located_in the gastrointestinal tract. (DOID) SNOMEDCT_US_2020_03_01:53619000 UMLS:C0012242 GIT disease Gastroenteropathy alimentary system disease digestive system disorder gastrointestinal disease gastrointestinal disorder DOID:77 gastrointestinal system disease DOID: 2021/01/28 DOID:77 A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide. (DOID) UMLS:C0024115 DOID:850 lung disease DOID: 2021/01/28 DOID:850 A disease by infectious agent that results in infection, has_material_basis_in Viruses. (DOID) UMLS:C0042769 DOID:934 viral infectious disease DOID: 2021/01/28 DOID:934 An eosinophilic pneumonia which slowly progresses over weeks to months. Life-threatening shortness of breath can develop if the condition is not treated. Individuals are often diagnosed with asthma before the advent of this disease. (DOID) UMLS:C0008680 DOID:9502 chronic eosinophilic pneumonia DOID: 2021/01/28 DOID:9502 An eosinophilic pneumonia described as a form of pulmonary eosinophilia characterized as a mild pneumonitis marked by transitory pulmonary infiltration and eosinophilia and usually considered to be an allergic reaction. It can occur in response to a parasitic infection. SNOMEDCT_US_2018_03_01:64936001 UMLS:C0242459 Loeffler's pneumonia Loffler's syndrome DOID:9503 Loeffler syndrome DOID: 2021/01/28 DOID:9503 An obstructive lung disease that is characterized by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. (DOID) Pulmonary emphysema is a disorder affecting the alveoli (tiny air sacs) of the lungs. The transfer of oxygen and carbon dioxide in the lungs takes place in the walls of the alveoli. In emphysema, the alveoli become abnormally inflated, damaging their walls and making it harder to breathe. People who smoke or have chronic bronchitis have an increased risk of emphysema. (NCI) HP:0006534 SNOMEDCT_US:87433001 UMLS:C0034067 emphysema DOID:9675 pulmonary emphysema DOID: 2021/01/28 DOID:9675 A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism. (HPO) SNOMEDCT_US:236423003 UMLS:C1565489 Renal failure Renal failure in adulthood HP:0000083 Renal insufficiency HP: 2020/12/07 HP:0000083 Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.MSH) Inflammation of the paranasal sinuses owing to a viral, bacterial, or fungal infection, allergy, or an autoimmune reaction. (HPO) MSH:D010254 MSH:D012852 SNOMEDCT_US:36971009 SNOMEDCT_US:7393007 SYMP:0000134 UMLS:C0037199 Sinus inflammation Sinus disease Sinus infection HP:0000246 Sinusitis HP: 2020/12/07 HP:0000246 An acute form of sinusitis. (HPO) SNOMEDCT_US:15805002 UMLS:C0149512 Acute inflammation of sinus HP:0000255 Acute sinusitis HP: 2020/12/07 HP:0000255 Bleeding from the nose. (NCI) Epistaxis, or nosebleed, refers to a hemorrhage localized in the nose. (HPO) MSH:D004844 SNOMEDCT_US:12441001 SNOMEDCT_US:249366005 SYMP:0000448 UMLS:C0014591 Bloody nose Frequent nosebleeds Nasal hemorrhage Nose bleeding Nosebleed HP:0000421 Epistaxis HP: 2020/12/07 HP:0000421 An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body. (HPO) MSH:D004487 SNOMEDCT_US:267038008 UMLS:C0013604 Dropsy Fluid retention Hydrops Oedema Water retention HP:0000969 Edema may be related to one or more of the following factors: 1) increased capillary hydrostatic pressure, 2) decreased osmotic pressure of plasma, 3) decreased tissue tension and lymphatic drainage, 4) increased osmotic pressure of tissue fluids, and 5) increased capillary permeability. Edema HP: 2020/12/07 HP:0000969 A red eruption of the skin. (HPO) MEDDRA:10037844 SNOMEDCT_US:271807003 UMLS:C0015230 Exanthem Rash HP:0000988 Skin rash HP: 2020/12/07 HP:0000988 Broadening of the soft tissues (non-edematous swelling of soft tissues) of the digital tips in all dimensions associated with an increased longitudinal and lateral curvature of the nails. Non-edematous swelling/broadening of the soft tissue of the fingertips in all dimensions (distal phalanges of the fingers). (HPO) SNOMEDCT_US:367004 UMLS:C0149651 Clubbing of fingers and toes Digital clubbing HP:0001217 Clubbing HP: 2020/12/07 HP:0001217 A rapid heartrate that exceeds the range of the normal resting heartrate for age. (HPO) MSH:D013610 SNOMEDCT_US:86651002 UMLS:C0039231 Fast heart rate Heart racing Racing heart HP:0001649 Tachycardia HP: 2020/12/07 HP:0001649 A reduction in the number of circulating thrombocytes. (HPO) MSH:D013921 SNOMEDCT_US:302215000 SNOMEDCT_US:415116008 UMLS:C0040034 UMLS:C0392386 Low platelet count HP:0001873 Thrombocytopenia can be divided into three major causes; 1) low production of platelets in the bone marrow; 2) intravascular breakdown of thrombocytes; and 3) increased turnover of platelets in spleen or liver (extravascular). Thrombocytopenia HP: 2020/12/07 HP:0001873 A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). (MSH) An abnormal decreased number of leukocytes in the blood. (HPO) MSH:D007970 SNOMEDCT_US:84828003 UMLS:C0023530 Decreased blood leukocyte number low white blood cell count HP:0001882 Leukopenia HP: 2020/12/07 HP:0001882 A reduced number of lymphocytes in the blood. (HPO) Reduction in the number of lymphocytes. (MSH) MSH:D008231 SNOMEDCT_US:48813009 UMLS:C0024312 Absolute lymphocyte count decrease Decreased blood lymphocyte number Low lymphocyte number Lymphocytopenia HP:0001888 Lymphopenia HP: 2020/12/07 HP:0001888 The condition that results from excessive loss of water from a living organism. (MSH) MSH:D003681 SNOMEDCT_US:34095006 UMLS:C0011175 Dehydration Exsiccosis HP:0001944 Dehydration HP: 2020/12/07 HP:0001944 A transient increase in the number of leukocytes in a body fluid. (MSH) An abnormal increase in the number of leukocytes in the blood. (HPO) SNOMEDCT_US:111583006 UMLS:C0023518 Elevated white blood count High white blood count Increased blood leukocyte number HP:0001974 Leukocytosis HP: 2020/12/07 HP:0001974 UMLS:C1112601 Hyperosmolar dehydration HP:0001986 Hypertonic dehydration HP: 2020/12/07 HP:0001986 An uncomfortable sensation of difficulty breathing. It may present as an acute or chronic sign of an underlying respiratory or heart disorder. (NCI) Difficult or labored breathing. (MSH) Difficulty in breathing. The physical presentation of respiratory distress is generally referred to as labored breathing, while the sensation of respiratory distress is called shortness of breath or dyspnea. (HPO) MSH:D004417 SNOMEDCT_US:230145002 SNOMEDCT_US:267036007 UMLS:C0013404 Abnormal breathing Breathing difficulty Difficult to breathe Dyspnoea Shortness of breath Trouble breathing HP:0002094 Dyspnea HP: 2020/12/07 HP:0002094 A finding indicating the presence of an inflammatory or neoplastic cellular infiltrate in the lung parenchyma. (NCI) UMLS:C0235896 Pneumonic infiltrates HP:0002113 Pulmonary infiltrates HP: 2020/12/07 HP:0002113 An embolus (that is, an abnormal particle circulating in the blood) located in the pulmonary artery and thereby blocking blood circulation to the lung. Usually the embolus is a blood clot that has developed in an extremity (for instance, a deep venous thrombosis), detached, and traveled through the circulation before becoming trapped in the pulmonary artery. (HPO) MSH:D011655 SNOMEDCT_US:59282003 UMLS:C0034065 Blood clot in artery of lung Pulmonary embolus HP:0002204 Pulmonary embolism HP: 2020/12/07 HP:0002204 A finding indicating the presence of an inflammatory or neoplastic cellular infiltrate in the lung parenchyma. (NCI) UMLS:C1843428 HP:0002207 Diffuse reticular or finely nodular infiltrations HP: 2020/12/07 HP:0002207 Chronic inflammation of the nasal cavity mucosa. It may lead to post-nasal drip resulting in chronic sore throat and chronic cough. (NCI) Chronic inflammation of the nasal mucosa. (HPO) SNOMEDCT_US:86094006 UMLS:C0008711 HP:0002257 Chronic rhinitis HP: 2020/12/07 HP:0002257 Paroxysmal, recurrent episodes of vomiting. (HPO) UMLS:C1838993 HP:0002572 Episodic vomiting HP: 2020/12/07 HP:0002572 Abnormal increase of rate of breathing. (NCI). Increased RESPIRATORY RATE. (MSH) Very rapid breathing. (HPO) MSH:D059246 SNOMEDCT_US:271823003 UMLS:C0231835 Increased respiratory rate or depth of breathing Polypnea HP:0002789 Tachypnea HP: 2020/12/07 HP:0002789 An increased susceptibility to bronchitis as manifested by a history of recurrent bronchitis. (HPO) UMLS:C0741796 Bronchitis, recurrent HP:0002837 Recurrent bronchitis HP: 2020/12/07 HP:0002837 SNOMEDCT_US:60845006 UMLS:C0231807 Exertional dyspnoea HP:0002875 Exertional dyspnea HP: 2020/12/07 HP:0002875 Episodes of very rapid breathing. (HPO) UMLS:C3806218 Hyperpnea, episodic HP:0002876 Episodic tachypnea HP: 2020/12/07 HP:0002876 A severe form of respiratory insufficiency characterized by inadequate gas exchange such that the levels of oxygen or carbon dioxide cannot be maintained within normal limits. (HPO) MSH:D012131 SNOMEDCT_US:409622000 UMLS:C1145670 HP:0004877 Respiratory failure HP: 2020/12/07 HP:0004877 A pathological increase in the effort and frequency of breathing movements. (NCI) Difficulty in breathing. The physical presentation of respiratory distress is generally referred to as labored breathing, while the sensation of respiratory distress is called shortness of breath or dyspnea. (HPO) MSH:D004417 SNOMEDCT_US:267036007 UMLS:C0476273 Breathing difficulties Difficulty breathing Respiratory difficulties Breathing difficulties Difficulty breathing Respiratory difficulties Short of breath Shortness of breath HP:0002880 Respiratory distress HP: 2020/12/07 HP:0002880 Abnormally low level of sodium in the blood. (NCI) An abnormally decreased sodium concentration in the blood. (HPO) SNOMEDCT_US:89627008 UMLS:C0020625 HP:0002902 Hyponatremia HP: 2020/12/07 HP:0002902 Reduction in the concentration of albumin in the blood. (HPO) UMLS:C0239981 Hypoalbuminaemia Low blood albumin Low albumin HP:0003073 Hypoalbuminemia HP: 2020/12/07 HP:0003073 Arthritis caused by BACTERIA; RICKETTSIA; MYCOPLASMA; VIRUSES; FUNGI; or PARASITES. (MSH) SNOMEDCT_US:372939007 SNOMEDCT_US:396234004 UMLS:C0003869 UMLS:C4280547 HP:0003095 Septic arthritis HP: 2020/12/07 HP:0003095 Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life. (NCI) It is characterized by one or more symptoms including sneezing, itching, nasal congestion, and rhinorrhea. (HPO) MSH:D065631 SNOMEDCT_US:61582004 UMLS:C2607914 Allergic rhinitis due to allergen AR - Allergic rhinitis Allergic rhinitis (disorder) Allergic rhinitis due to allergen Atopic rhinitis HP:0003193 Allergic rhinitis HP: 2020/12/07 HP:0003193 Pain in muscle. (HPO) MSH:D063806 SNOMEDCT_US:68962001 UMLS:C0231528 Muscle ache Muscle pain HP:0003326 Myalgia HP: 2020/12/07 HP:0003326 UMLS:C3809715 Recurrent epistaxes Recurrent epistaxis Recurring nosebleed Spontaneous, recurrent nosebleed HP:0004406 Spontaneous, recurrent epistaxis HP: 2020/12/07 HP:0004406 Chronic inflammation of the bronchi. (HPO) MSH:D029481 SNOMEDCT_US:63480004 UMLS:C0008677 HP:0004469 Chronic bronchitis HP: 2020/12/07 HP:0004469 UMLS:C4025318 Chronic nasal inflammation due to narrow nasal airway HP:0004499 Chronic rhinitis due to narrow nasal airway HP: 2020/12/07 HP:0004499 A narrow complex (QRS width less than 120 milliseconds) reflects rapid activation of the ventricles via the normal conduction pathway, i.e. His-Purkinje system, which in turn suggests that the tachycardia originated above the AV node and is thus supraventricular. Supraventricular tachycardia (SVT) is an abnormally increased heart rate (over 100 beats per minute at rest) with origin above the level of the ventricles. (HPO) MSH:D013617 SNOMEDCT_US:6456007 UMLS:C0039240 SVT Supraventricular tachyarrhythmia HP:0004755 Supraventricular tachycardia HP: 2020/12/07 HP:0004755 A tachycardia originating in the ventricles characterized by rapid heart rate (over 100 beats per minute) and broad QRS complexes (over 120 ms). Ventricular tachycardia (VT) is a potentially life-threatening ventricular arrhythmia that presents as a wide QRS complex tachycardia, and is defined as three or more consecutive QRS complexes with a duration longer than 120 milliseconds (ms) and a rate of 100 beats per minute or more, whereby the complexes have a ventricular origin. VT can be subdivided as follows: (i) sustained VT persists for 30 seconds or more; (ii) non-sustained VT lasts less than 30 seconds; (iii) monomorphic VT displays a uniform QRS morphology; and (iv) polymorphic VT displays QRS morphologies that variy from beat to beat. VT is observed most commonly in individuals with structural heart disease or acute myocardial infarction (MI). VT may also be observed in in the setting of drug toxicity or electrolyte abnormalities or in individuals with Mendelian disease. (HPO) MSH:D017180 SNOMEDCT_US:25569003 UMLS:C0042514 HP:0004756 Ventricular tachycardia HP: 2020/12/07 HP:0004756 UMLS:C1844945 Episodic difficulty breathing respiratory distress, episodic HP:0004885 Episodic respiratory distress HP: 2020/12/07 HP:0004885 SNOMEDCT_US:427784006 UMLS:C1850544 HP:0004906 Hypernatremic dehydration HP: 2020/12/07 HP:0004906 An atrial arrhythmia characterized by disorganized atrial activity without discrete P waves on the surface EKG, but instead by an undulating baseline or more sharply circumscribed atrial deflections of varying amplitude an frequency ranging from 350 to 600 per minute. (HPO) MSH:D001281 SNOMEDCT_US:49436004 UMLS:C0004238 HP:0005110 Atrial fibrillation HP: 2020/12/07 HP:0005110 UMLS:C3805920 HP:0005828 Transient pulmonary infiltrates HP: 2020/12/07 HP:0005828 Episodes of reduced body termperature. (HPO) UMLS:C1837639 HP:0005964 Intermittent hypothermia HP: 2020/12/07 HP:0005964 A rapid heartrate that exceeds the range of the normal resting heartrate for age. (HPO) MSH:D013614 SNOMEDCT_US:12026006 UMLS:C0039236 HP:0006688 Paroxysmal tachycardia HP: 2020/12/07 HP:0006688 An increased susceptibility to meningitis as manifested by a medical history of recurrent episodes of meningitis. (HPO) UMLS:C0746495 HP:0006946 Recurrent meningitis HP: 2020/12/07 HP:0006946 An increased susceptibility to bacterial meningitis as manifested by a medical history of recurrent episodes of bacterial meningitis. (HPO) UMLS:C1845604 HP:0007274 Recurrent bacterial meningitis HP: 2020/12/07 HP:0007274 Cutaneous lesion that develops as a dry, scaly, red patch that evolves to an indurated and hyperpigmented plaque with adherent scale. Scarring may result in central white patches (loss of pigmentation) and skin atrophy. This lesion is characterstic of discoid lupus erythematosus, but similar lesions may be observed in other diseases. (HPO) MSH:D008179 SNOMEDCT_US:200938002 SNOMEDCT_US:238927000 UMLS:C0024138 Discoid lupus erythematosus HP:0000981 Discoid lupus rash HP: 2020/12/07 HP:0000981 A recurrent form of sinusitis. Recurring inflammation of the paranasal sinuses. (HPO) SNOMEDCT_US:195788001 UMLS:C0581354 HP:0011108 Recurrent sinusitis HP: 2020/12/07 HP:0011108 SNOMEDCT_US:40055000 UMLS:C0149516 UMLS:C0748720 Chronic sinus disease Sinusitis, chronic HP:0011109 Chronic sinusitis HP: 2020/12/07 HP:0011109 Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both. (HPO) Arrhythmias Cardiac arrhythmia Cardiac arrhythmias Cardiac rhythm disturbances Heart rhythm disorders Irregular heart beat Irregular heartbeat HP:0011675 Arrhythmia HP: 2020/12/07 HP:0011675 Elevation in the concentration of albumin in the blood. (HPO) UMLS:C1142113 High blood albumin levels Hyperalbuminaemia High albumin HP:0012117 Hyperalbuminemia HP: 2020/12/07 HP:0012117 An exanthema consisting of widespread pink-to-red macules (flat spots of 2-10 mm in diameter) or papules (red bumps) that blanch with pressure. The macules and papules may cluster and merge to form sheets over several days. A morbilliform rash is said to resemble the rash of measles, rubella or scarlet fever, thus mimicking viral and bacterial exanthemas. (HPO) SNOMEDCT_US:247470007 SNOMEDCT_US:50495000 UMLS:C0234918 HP:0012282 Morbilliform rash HP: 2020/12/07 HP:0012282 A subjective feeling of tiredness characterized by a lack of energy and motivation. (HPO) SNOMEDCT_US:248274002 SNOMEDCT_US:84229001 SYMP:0019177 UMLS:C0015672 Tired Tiredness Weariness Malaise HP:0012378 Fatigue HP: 2020/12/07 HP:0012378 An inflammation of the mucous membrane lining the nose, usually associated with nasal discharge. (NCI) Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES. (MSH) Inflammation of the nasal mucosa with nasal congestion. (HPO) MSH:D012220 SNOMEDCT_US:70076002 SYMP:0000121 UMLS:C0035455 UMLS:C2718128 HP:0012384 Rhinitis HP: 2020/12/07 HP:0012384 Inflammation (swelling and reddening) of the bronchi. (NCI) MSH:D001991 SNOMEDCT_US:32398004 UMLS:C0006277 HP:0012387 Bronchitis HP: 2020/12/07 HP:0012387 Inflammation of the large airways of the lung with rapid onset and short course usually associated with cough, mucus production, shortness of breath, wheezing, and chest tightness. (HPO) SNOMEDCT_US:10509002 SNOMEDCT_US:35301006 UMLS:C0149514 HP:0012388 Acute bronchitis HP: 2020/12/07 HP:0012388 An abnormally low level of blood oxygen. Note that hypoxemia is defined as a condition where arterial oxygen tension is below normal (80-100mmHg). Hypoxia is defined as the failure of oxygenation at the tissue level. Hypoxia is not measured directly by a standard laboratory value. (HPO) MSH:D000860 SNOMEDCT_US:389087006 UMLS:C0700292 Low blood oxygen level Hypoxia Low blood oxygen level HP:0012418 Hypoxemia HP: 2020/12/07 HP:0012418 Intermittent and recurrent bouts of a subjective feeling of tiredness characterized by a lack of energy and motivation. (HPO) UMLS:C4022907 HP:0012431 Episodic fatigue HP: 2020/12/07 HP:0012431 Subjective feeling of tiredness characterized by a lack of energy and motivation that persists for six months or longer. (HPO) UMLS:C0518656 HP:0012432 Chronic fatigue HP: 2020/12/07 HP:0012432 Paroxysmal nocturnal dyspnea (PND) is a sensation of shortness of breath that awakens the patient, often after 1 or 2 hours of sleep, and is usually relieved in the upright position. A sudden attack of dyspnea that occurs while the affected person is at rest. (HPO) SNOMEDCT_US:59265000 UMLS:C0013405 Paroxysmal dyspnoea HP:0012763 Paroxysmal dyspnea HP: 2020/12/07 HP:0012763 A sensation of breathlessness in the recumbent position, relieved by sitting or standing. (HPO) SNOMEDCT_US:62744007 UMLS:C0085619 HP:0012764 Orthopnea HP: 2020/12/07 HP:0012764 The intensity or degree of a manifestation. (HPO) SNOMEDCT_US:103370009 UMLS:C0522510 HP:0012824 Severity HP: 2020/12/07 HP:0012824 Having a relatively minor degree of severity. For quantitative traits, a deviation of between two and three standard deviations from the appropriate population mean. (HPO) SNOMEDCT_US:446411000124101 UMLS:C1513302 HP:0012825 Mild HP: 2020/12/07 HP:0012825 Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. (HPO) SNOMEDCT_US:446421000124109 SNOMEDCT_US:6736007 UMLS:C0205081 HP:0012826 Moderate HP: 2020/12/07 HP:0012826 Having a minor degree of severity that is considered to be on the boundary between the normal and the abnormal ranges. For quantitative traits, a deviation of that is less than two standard deviations from the appropriate population mean. (HPO) UMLS:C0205189 HP:0012827 Borderline HP: 2020/12/07 HP:0012827 Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. SNOMEDCT_US:24484000 UMLS:C0205082 HP:0012828 Severe HP: 2020/12/07 HP:0012828 Having an extremely high degree of severity. For quantitative traits, a deviation of more than five standard deviations from the appropriate population mean. SNOMEDCT_US:7950021 UMLS:C0439808 HP:0012829 Profound HP: 2020/12/07 HP:0012829 Vomiting of material that is of fecal origin. (HPO) UMLS:C0241706 Fecal vomiting Stercoraceous vomiting Vomiting fecal matter HP:0025089 Feculent vomiting HP: 2020/12/07 HP:0025089 A sudden sensation of feeling cold. (HPO) Shivering or moderate tremors of the body often accompanied by a cold sensation. A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a fever. Shivering or moderate tremors of the body, this is often accompanied by a cold sensation. (NCI) The sudden sensation of being cold. It may be accompanied by SHIVERING. (MSH) UMLS:C0085593 HP:0025143 Chills HP: 2020/12/07 HP:0025143 A sensation of tightness in the neck when attempting to move it, especially after a period of inactivity. Neck stiffness often involves soreness and difficulty moving the neck, especially when trying to turn the head to the side. (HPO) Limited mobility of the neck, usually accompanied by pain. (NCI) Neck stiffness HP:0025258 Stiff neck HP: 2020/12/07 HP:0025258 This type of rash is seen in lupus erythematosus, but also in other diseases such as rosacea and seborrheic dermatitis. An erythematous (red), flat facial rash that affects the skin in the malar area (over the cheekbones) and extends over the bridge of the nose. (HPO) UMLS:C4280745 Butterfly rash Cheekbone rash HP:0025300 Malar rash HP: 2020/12/07 HP:0025300 Wheezes and rhonchi are continuous musical lung sounds. The American Thoracic Society (ATS) Committee on pulmonary nomenclature defines wheezes as high-pitched continuous sounds with a dominant frequency of 400 Hz or more, and rhonchi as low-pitched continuous musical sounds with a dominant frequency of about 200 Hz or less A high-pitched whistling sound associated with labored breathing. MSH:D012135 SNOMEDCT_US:56018004 UMLS:C0043144 wheeze HP:0030828 wheezing HP: 2020/12/07 HP:0030828 An anomalous (adventitious) sound produced by the breathing process. (HPO) SNOMEDCT_US:301273002 UMLS:C0231856 abnormal chest sound bronchial breath sound HP:0030829 Abnormal breath sound HP: 2020/12/07 HP:0030829 Purple eyelids, which are described as heliotrope, as they resemble the heliotrope flower, e.g., Heliotropium peruvianum, which has small purple petals. Heliotrope rash is one of the characteristic skin manifestations of juvenile dermatomyositis. It is a reddish-purple rash on the upper eyelids that is usually bilateral. Heliotrope rash is a violaceous discoloration of the eyelids associated with periorbital edema. (HPO) UMLS:C4280745 HP:0030845 Heliotrope rash of eyelid HP: 2020/12/07 HP:0030845 Enlargement of the nostrils during breathing; although there are many possible causes, it can be a sign of respiratory distress in young infants. (NCI) Widening of the nostrils upon inhalation as a manifestation of respiratory distress. (HPO) SNOMEDCT_US:21558008 SNOMEDCT_US:248568003 UMLS:C0277873 HP:0030863 Nasal flaring HP: 2020/12/07 HP:0030863 A pulling inward of the soft tissues between the ribs upon inhalation. This is a sign of increased use of the chest muscles for breathing and is a manifestation of respiratory distress. (HPO) The marked inward movement of the muscles between the ribs during inhalation, indicating that there is reduced pressure in the thoracic cavity, and which can be a sign of breathing difficulties. (NCI) SNOMEDCT_US:6442005 UMLS:C0425470 Chest retractions HP:0030864 Intercostal retractions HP: 2020/12/07 HP:0030864 Oxygen saturation less than 95% on exertion or arterial partial pressure of oxygen falling by more than 1kPa. (HPO) UMLS:C4280731 O2 desaturation on exertion HP:0030874 Oxygen desaturation on exertion HP: 2020/12/07 HP:0030874 A subjective feeling of tiredness characterized by a lack of energy and motivation and that is induced by exertion or exercise. (HPO) UMLS:C2732413 Exercise-induced fatigue Exercise-induced malaise postexertional fatigue HP:0030973 Postexertional fatigue HP: 2020/12/07 HP:0030973 A cough accompanied by expectorated secretions. (NCI) A cough that produces phlegm or mucus. (HPO) SNOMEDCT_US:28743005 UMLS:C0239134 Producing sputum Wet cough Loose cough Moist cough Producing sputum Productive cough (finding) HP:0031245 Productive cough HP: 2020/12/07 HP:0031245 The term whooping cough is usually used to describe the disease caused by infection of the respiratory tract with Bordatella pertussis. This HPO term refers to the major symptom of that disease. A type of cough characterized by a burst of numerous and rapid coughs followed by a long inhaling effort that is accompanied by a high-pitched whooping sound produced by the inhalation of air. HP:0031247 Whooping cough HP: 2020/12/07 HP:0031247 A discharge of fluid from the nose. (NCI) Increased discharge of mucus from the nose. (HPO) SNOMEDCT_US:64531003 SYMP:0000701 UMLS:C1260880 Nasal discharge Runny Nose HP:0031417 Rhinorrhea HP: 2020/12/07 HP:0031417 Squawks are found in pulmonary fibrosis of various causes, particularly in hypersensitivity pneumonitis. Other causes are detected in pneumonia and bronchiolitis obliterans. Squawks are short inspiratory wheezes of less than 200 msduration and are also known as squeaks. Acoustic analysis shows the fundamental frequency varying between 200 and 300 Hz. Squawks usually occur in late inspiration and areoften preceded by late inspiratory crackles. UMLS:C4732797 HP:0031995 Squawks are found in pulmonary fibrosis of various causes, particularly in hypersensitivity pneumonitis. Other causes are detected in pneumonia and bronchiolitis obliterans. Squawks HP: 2020/12/07 HP:0031995 Abnormal appearance of material expectorated (coughed up) from the respiratory system and that is composed of mucus but may contain other substances such as pus, blood, microorganisms, and fibrin. (HPO) SNOMEDCT_US:274708000 UMLS:C0159054 HP:0032016 Abnormal sputum HP: 2020/12/07 HP:0032016 Sputum eosinophilia can be measured in various ways including measuing the mean percentage of eosinophils in the cell count of sputum induced by application of saline. The threshold chosen differs between studies, typically ranging from 1.25 to 3 percent. Increased sputum eosinophil counts may indicate a risk for severe chronic obstructive pulmonary disease or severe asthma. An increased proportion of eosinophils in sputum in the differentiated cell count. (HPO) UMLS:C0241234 HP:0032017 Sputum eosinophilia can be measured in various ways including measuing the mean percentage of eosinophils in the cell count of sputum induced by application of saline. The threshold chosen differs between studies, typically ranging from 1.25 to 3 percent. Increased sputum eosinophil counts may indicate a risk for severe chronic obstructive pulmonary disease or severe asthma. Sputum eosinophilia HP: 2020/12/07 HP:0032017 Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (MSH) UMLS:C0085436 Meningitis due to Cryptococcus SNOMEDCT_US:14232007 Cryptococcal meningitis HP: 2020/12/07 SNOMEDCT_US:14232007 Expectoration (coughing up) of a broncholith. Broncholithiasis is defined as the presence of calculi in the tracheobronchial tree. It is a rare disease but can be characterized by clinical and radiological findings of a calcified lymph node eroding bronchial wall and opening into the bronchial lumen. (HPO) HP:0032543 Lithoptysis HP: 2020/12/07 HP:0032543 A failure to sustain attention that requires self-motivation to optimize performance. Cognitive fatigue may be observed as decreased performance following prolonged effort over an extended period of time; decreased performance after a challenging mental exertion; decreased performance after a challenging physical exertion; and decreased performance during acute but sustained mental effort. (HPO) UMLS:C2732413 Central fatigue HP:0033236 Cognitive fatigue may be observed as decreased performance following prolonged effort over an extended period of time; decreased performance after a challenging mental exertion; decreased performance after a challenging physical exertion; and decreased performance during acute but sustained mental effort. Cognitive fatigue HP: 2020/12/07 HP:0033236 A skin rash that is characterized by diffuse cutaneous erythema with areas of skin elevation. It may evolve to vesicles or papules as part of a more severe clinical entity. Different degrees of angioedema with involvement of subcutaneous tissue may also appear. (HPO) SNOMEDCT_US:247471006 SNOMEDCT_US:47725002 UMLS:C0423791 HP:0040186 Maculopapular exanthema HP: 2020/12/07 HP:0040186 In a heliotrope rash, the color of the skin turns to violet, which is the color of the heliotrope flower. Heliotrope rash occurs during the initial phase of the idiopathic inflammatory myositis (particularly dermatomyositis). Heliotrope rash is a characteristic symptom of Dermatomyositis. (HPO) Heliotrope erythema HP:0040324 Heliotrope rash HP: 2020/12/07 HP:0040324 A cutaneous eruption that consists of multiple (at least two) concentric erythematous rings. (HPO) UMLS:C4551694 HP:0040325 Bull's eye rash HP: 2020/12/07 HP:0040325 Chronic rhinitis accompanied by pus formation. An infection of the nasal mucosa associated with pus formation. (Often secondary to a systemic infection, such as measles) UMLS:C0264272 HP:0040334 An infection of the nasal mucosa associated with pus formation. (Often secondary to a systemic infection, such as measles) Purulent rhinitis HP: 2020/12/07 HP:0040334 Bradypnea is referring to breathing that is abnormally slow. (HPO) SNOMED_CT:86684002 UMLS:C0231837 HP:0046507 Bradypnea HP: 2020/12/07 HP:0046507 An increased susceptibility to bronchiolitis as manifested by a history of recurrent bronchiolitis. (HPO) UMLS:C4015136 Bronchitis, recurrent HP:0100501 Recurrent bronchiolitis HP: 2020/12/07 HP:0100501 An inflammation of the endocardium, the inner layer of the heart, which usually involves the heart valves. (HPO) MSH:D004696 SNOMEDCT_US:56819008 UMLS:C0014118 HP:0100584 Endocarditis HP: 2020/12/07 HP:0100584 Fluid accumulation in the lungs. (HPO) MSH:D011654 SNOMEDCT_US:19242006 UMLS:C0034063 Excess fluid in lungs Lung edema Pulmonary oedema Wet lung HP:0100598 Pulmonary edema HP: 2020/12/07 HP:0100598 MEDDRA:10016680 MSH:D010005 SNOMEDCT_US:30760008 UMLS:C0009080 Clubbed fingers Clubbing (hands) Clubbing of fingers Finger clubbing HP:0100759 Clubbing of fingers HP: 2020/12/07 HP:0100759 Terminal broadening of the toes (distal phalanges of the toes). (HPO) MSH:D003025 SNOMEDCT_US:249808002 SNOMEDCT_US:397932003 SNOMEDCT_US:53148007 UMLS:C0009081 UMLS:C3887489 Clubbed toes HP:0100760 Clubbing of toes HP: 2020/12/07 HP:0100760 Systemic inflammatory response to infection. (HPO) UMLS:C0243026 HP:0100806 Sepsis HP: 2020/12/07 HP:0100806 IAO:0000027 data item An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. data item IAO:0000030 information content entity A generically dependent continuant that is about some thing. information content entity IAO:0000033 An information content entity whose concretizations indicate to their bearer how to realize them in a process. directive information entity IAO:0000078 curation status specification The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting) PERSON:Bill Bug GROUP:OBI:<http://purl.obolibrary.org/obo/obi> OBI_0000266 curation status specification IAO:0000102 data about an ontology part Data about an ontology part is a data item about a part of an ontology, for example a term Person:Alan Ruttenberg data about an ontology part IAO:0000225 obsolescence reason specification The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology. PERSON: Alan Ruttenberg PERSON: Melanie Courtot obsolescence reason specification IAO:0000409 denotator type The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are "natural kinds" and the latter arbitrary collections of entities. A denotator type indicates how a term should be interpreted from an ontological perspective. Alan Ruttenberg Barry Smith, Werner Ceusters denotator type IAO:8000000 ontology module I have placed this under 'data about an ontology part', but this can be discussed. I think this is OK if 'part' is interpreted reflexively, as an ontology module is the whole ontology rather than part of it. ontology file This class and it's subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology. ontology module IAO:8000001 base ontology module An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies. base ontology module IAO:8000002 editors ontology module An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users. source ontology module editors ontology module IAO:8000003 main release ontology module An ontology module that is intended to be the primary release product and the one consumed by the majority of tools. TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module main release ontology module IAO:8000004 bridge ontology module An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module. bridge ontology module IAO:8000005 import ontology module A subset ontology module that is intended to be imported from another ontology. TODO: add axioms that indicate this is the output of a module extraction process. import file import ontology module IAO:8000006 subset ontology module An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms. ontology slim subset ontology subset ontology module IAO:8000007 curation subset ontology module A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation. curation subset ontology module IAO:8000008 analysis ontology module An ontology module that is intended for usage in analysis or discovery applications. analysis subset ontology module IAO:8000009 single layer ontology module A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint. ribbon subset single layer subset ontology module IAO:8000010 exclusion subset ontology module A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes. antislim exclusion subset ontology module IAO:8000011 external import ontology module An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach. external import external import ontology module IAO:8000012 species subset ontology module A subset ontology that is crafted to either include or exclude a taxonomic grouping of species. taxon subset species subset ontology module IAO:8000013 reasoned ontology module An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available. reasoned ontology module IAO:8000014 generated ontology module An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV. TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process generated ontology module IAO:8000015 template generated ontology module An ontology module that is automatically generated from a template specification and fillers for slots in that template. template generated ontology module IAO:8000016 taxonomic bridge ontology module taxonomic bridge ontology module IAO:8000017 ontology module subsetted by expressivity ontology module subsetted by expressivity IAO:8000018 obo basic subset ontology module A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools. Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses). An ontology is OBO Basic if and only if it has the following characteristics: DAG Unidirectional No Dangling Clauses Fully Asserted Fully Labeled No equivalence axioms Singly labeled edges No qualifier lists No disjointness axioms No owl-axioms header No imports obo basic subset ontology module IAO:8000019 ontology module subsetted by OWL profile ontology module subsetted by OWL profile IAO:8000020 EL++ ontology module EL++ ontology module A role borne by an infectious agent when contained in a host in which its infectious disposition can be realized. IDO:0000404 infectious agent role IDO: 2017/11/03 IDO:0000404 IDO:A role borne by pathogen in virtue of the fact that it or one of its products is sufficiently close to an organism towards which it has the pathogenic disposition to allow realization of the pathogenic disposition. IDO:0000405 Clostridium botulinum is an example of an entity with the capability to bear the pathogen role but that does not have the capability to bear the infectious agent role or the parasite role. The influenza viruses are examples of organisms that can bear both the infectious agent and pathogen roles. pathogen role IDO: 2017/11/03 IDO:0000405 An infectious disposition to become part of a disorder only in organisms whose defenses are compromised. (IDO) opportunitistic pathogenic disposition IDO:0000406 The disposition is realized in a process by which the bearer becomes part of a disorder in an immunocompromised host. This includes individuals who are immunocompromised or who have damaged barriers that normally protect against infection (e.g. skin). opportunistic infectious disposition IDO: 2017/11/03 IDO:0000406 An infectious disposition to become part of a disorder in organisms that have intact defenses. (IDO) IDO:0000407 A pathogen with a primary infectious disposition can cause disease or death in both immunocompromised and immunocompetent hosts. A quote from page 3 of Mandell's "Principles and Practice of Infectious Diseases" (Sixth edition): "It is useful to distinguish "principal" pathogens, which regularly cause disease in some proportion of susceptible individuals with apparently intact defense systems, from other potentially pathogenic microorganisms. ... even for most organisms classified as principal pathogens, for example, Staphylococcus aureus and the pneumococcus, some impairment or local breakdown in normal host defense mechanisms must occur for these bacteria to cause disease. ... Thus, it seems clear that the capacity of certain microorganisms to cause disease in seemingly uncompromised human hosts on a regular basis reflects some fundamental difference in their virulence capabilities from those of opportunists and the more numerous commensal species that rarely, if ever, cause disease." primary infectious disposition IDO: 2017/11/03 IDO:0000407 A disease whose physical basis is an infectious disorder. (IDO) transmissible disease IDO:0000436 infectious disease IDO: 2017/11/03 IDO:0000436 IDO: A disposition to initiate processes that result in a disorder. pathogenicity IDO:0000450 A pathogenic disposition is realized in processes that create a disorder. The use of 'initiates' is intended to convey that a pathogenic disposition is realized when processes resulting in a disorder begin because of some action on the part of the bearer of the disposition. By this interpretation of 'initiates', disorder-causing entities such as glass, UV light, and toxins do not have a pathogenic disposition. pathogenic disposition IDO: 2017/11/03 IDO:0000450 IDO:A pathogenic disposition that inheres in an organism and is a disposition for that organism (1) to be transmitted to a host, (2) to establish itself in the host, (3) to initiate processes that result in a disorder in the host, and (4) to become part of that disorder. IDO:0000452 The disposition is realized in a process that has as part a transmission process, an establishment in host process, a process that results in a disorder, and a process in which the bearer of the disposition becomes part of that disorder. The infectious disposition has a complementary disposition that inheres in an organism and is the capability to be host to an organism with an infectious disposition and to undergo processes initiated by that infectious organism that result in a disorder. infectious disposition IDO: 2017/11/03 IDO:0000452 An infectious disposition that is the disposition to be transmitted from an infected, non-human host to a human host. (IDO) IDO:0000453 An infectious disease associated with an infectious agent that bears the zoonotic disposition is referred to as a zoonosis. zoonotic disposition IDO: 2017/11/03 IDO:0000453 An infectious disposition that is the disposition to be transmitted from an infected, human host to a non-human host. (IDO) IDO:0000454 An infectious disease associated with an infectious agent that bears the reverse zoonotic disposition is referred to as a reverse zoonosis. reverse zoonotic disposition IDO: 2017/11/03 IDO:0000454 IDO:0000504 An infection that is clinically abnormal. infectious disorder IDO:0000586 A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population. infection An organism that has an infectious disposition. (IDO) IDO:0000596 Infectious agent IDO: 2017/11/03 IDO:0000596 IDO: An infectious disposition to be transmitted directly from one organism to another of the same Species by horizontal transmission. IDO:0000623 The disposition is realized in a direct, horizontal transmission process between members of the same Species. communicability IDO: 2017/11/03 IDO:0000623 IDO:0000630 An infection resulting from a transmission process that unfolds in a hospital. hospital-acquired infection OBI:0000011 A process that realizes a plan which is the concretization of a plan specification. planned process OBI:0000278 a part of an occurrence of a disease process which is associated with position in the normal progression of the disease disease stage OGMS:0000014 A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T10:18:02Z clinical finding OGMS:0000015 A series of statements representing health-relevant qualities of a patient and of a patient's family. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T10:18:59Z clinical history OGMS:0000016 A representation of clinically significant bodily components, dispositions, and/or bodily processes of a human being that is inferred from relevant clinical findings. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T10:20:20Z clinical picture OGMS:0000017 A representation of an image that supports an inference to an assertion about some quality of a patient. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T10:21:10Z image finding OGMS:0000018 A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T10:21:58Z laboratory finding OGMS:0000019 A representation of a quality of a patient that is (1) recorded by a clinician because the quality is hypothesized to be of clinical significance and (2) refers to qualities obtaining in the patient prior to their becoming detectable in a clinical history taking or physical examination. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T10:22:44Z preclinical finding OGMS:0000020 A process experienced by the patient, which can only be experienced by the patient, that is hypothesized to be clinically relevant. note: defined class http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-11-18T11:02:10Z Updated: 2020-07-06 symptom OGMS:0000022 A quality of a patient that is (a) a deviation from clinical normality that exists in virtue of the realization of a disease and (b) is observable. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:12:33Z manifestation of a disease OGMS:0000023 A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T11:13:49Z phenotype OGMS:0000024 The class sign has been replaced by three seperate classes which reflect the different types of signs possible. obsolete_sign true OGMS:0000025 A manifestation of a disease that is detectable in a clinical history taking or physical examination. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:15:43Z clinical manifestation of a disease OGMS:0000026 A manifestation of a disease that exists prior to the time at which it would be detected in a clinical history taking or physical examination, if the patient were to present to a clinician. A realization of a disease that exists prior to its becoming detectable in a clinical history taking or physical examination. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:16:50Z preclinical manifestation of a disease OGMS:0000027 A clinically abnormal phenotype. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:18:05Z clinical phenotype OGMS:0000028 A clinically abnormal phenotype that is characteristic of a single disease. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:18:39Z disease phenotype OGMS:0000029 A physical sign in which a non-zero value is standardly considered to be an indication that the organism is alive. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:19:17Z vital sign OGMS:0000030 A disposition in an organism that constitutes an increased risk of the organism's subsequently developing the disease X. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:20:25Z predisposition to disease of type X OGMS:0000031 A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:21:20Z disease OGMS:0000032 Albert Goldfain creation date: 2009-06-23T11:22:01Z homeostasis OGMS:0000033 A predisposition to disease of type X whose physical basis is a constitutional abnormality in an organism's genome. This abnormality is the physical basis for the increased risk of acquiring the disease X. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:23:07Z genetic predisposition to disease of type X OGMS:0000034 A disease whose physical basis is an acquired genetic disorder. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:24:05Z acquired genetic disease OGMS:0000035 A disease whose physical basis is a constitutional genetic disorder. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:24:59Z constitutional genetic disease OGMS:0000037 Homeostasis that is clinically abnormal for an organism of a given type and age in a given environment. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:26:44Z abnormal homeostasis OGMS:0000038 Homeostasis of a type that is not clinically abnormal. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:27:28Z normal homeostasis OGMS:0000039 A quality which is an spatial arrangement or distribution of a(n) independent continuant(s) across a Three Dimensional Region. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:36:24Z configuration OGMS:0000040 A configuration which deviates in some way from a canonical configuration for a particular organism. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:36:58Z pathological physical configuration OGMS:0000045 A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:39:44Z disorder OGMS:0000046 A disorder whose etiology involves (1) a modification to the patient's genomic DNA which leads to alterations in the normal expression pattern of the genome, but is (2) not a change in the nucleotide sequence. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:40:27Z epigenetic disorder OGMS:0000047 A disorder whose etiology involves an abnormality in the nucleotide sequence of an organism's genome. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:41:14Z genetic disorder OGMS:0000050 A genetic disorder acquired by a single cell in an organism that leads to a population of cells within the organism bearing the disorder. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:43:09Z acquired genetic disorder OGMS:0000051 A genetic disorder inherited during conception that is part of all cells in the organism. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:43:44Z constitutional genetic disorder OGMS:0000055 A health care process in which a clinician elicits a description of previous sign and symptoms of disease from a patient or from a third party who is reporting on behalf of the patient. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:49:16Z clinical history taking OGMS:0000056 A measurement assay that has as input a patient-derived specimen and as output a data item that is about a quality of the specimen. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:49:49Z clinical laboratory test OGMS:0000057 A sequence of acts of observing and measuring qualities of a patient performed by a clinician; measurements may occur with and without elicitation. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2010-07-19T11:50:18Z physical examination OGMS:0000059 A process in an organism that leads to a subsequent disorder. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:53:07Z etiological process OGMS:0000060 Albert Goldfain creation date: 2009-06-23T11:53:49Z bodily process OGMS:0000061 A bodily process that is clinically abnormal. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:54:29Z pathological bodily process OGMS:0000063 The totality of all processes through which a given disease instance is realized. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:55:44Z disease course OGMS:0000064 A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:56:26Z 10212020 for definition use: http://purl.obolibrary.org/obo/PATO_0001863 chronic disease course OGMS:0000065 A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, involve an increasing deviation from homeostasis. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:57:09Z progressive disease course OGMS:0000066 A disease course that terminates in a return to normal homeostasis. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T11:57:44Z transient disease course OGMS:0000067 Albert Goldfain creation date: 2009-06-23T11:58:22Z _undefined primitive term OGMS:0000069 Albert Goldfain creation date: 2009-06-23T11:59:24Z clinically abnormal OGMS:0000070 Albert Goldfain creation date: 2009-06-23T12:00:09Z physical basis OGMS:0000071 Albert Goldfain creation date: 2009-06-23T12:00:39Z realization OGMS:0000073 The representation of a conclusion of a diagnostic process. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-23T12:42:23Z diagnosis OGMS:0000074 A value for a quality reported in a lab report and asserted by the testing lab or the kit manufacturer to be normal based on a statistical treatment of values from a reference population. Albert Goldfain http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf creation date: 2009-06-26T10:31:34Z normal value OGMS:0000077 TODO: Define, relate to disorder, and place in the OGMS hierarchy. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:14:59Z pathological formation OGMS:0000078 An anatomical structure (FMA) is pathological whenever (1) it has come into being as a result of changes in some pre-existing canonical anatomical structure, (2) through processes other than the expression of the normal complement of genes of an organism of the given type, and (3) is predisposed to have health-related consequences for the organism in question manifested by symptoms and signs. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:14:05Z pathological anatomical structure OGMS:0000079 TODO: Define, relate to disorder, and place in the OGMS hierarchy. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:15:17Z portion of pathological body substance OGMS:0000080 A pathological bodily process in which a canonical anatomical structure becomes a pathological anatomical structure. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:17:07Z pathological transformation OGMS:0000081 A pathological bodily process in which matter is reorganized in such a way as to give rise to new pathological formations which take the place of entities existing earlier. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:17:24Z pathological derivation OGMS:0000082 TODO: Define. Albert Goldfain http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf creation date: 2009-07-13T02:17:47Z pathological invasion OGMS:0000083 TODO: Define. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=26 creation date: 2009-11-24T04:51:11Z physical examination finding OGMS:0000084 An aggregate of organisms of the same type. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=33 creation date: 2009-11-24T04:51:11Z organism population OGMS:0000085 A bodily process in an organism S involving two integrated levels: (a) activation of the nociceptive system and associated emotion generating brain components of S, and (b) a simultaneous aversive sensory and emotional experience on the part of S, where (b) is phenomenologically similar to the sort of aversive experience involved in pain with concordant tissue damage. Albert Goldfain http://www.referent-tracking.com/RTU/sendfile/?file=painTokyo1_27_2011.pdf creation date: 2009-11-24T04:51:11Z pain OGMS:0000086 A pattern of signs and symptoms that typically co-occur. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=32 creation date: 2009-11-24T04:51:11Z syndrome OGMS:0000087 An object aggregate consisting of an organism and all material entities located within the organism, overlapping the organism, or occupying sites formed in part by the organism. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=3 creation date: 2010-01-25T04:51:11Z extended organism OGMS:0000088 A communication from a patient about something they perceive as being abnormal about their body or life. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=12 creation date: 2010-01-25T04:51:11Z patient symptom report OGMS:0000089 A structurally anomalous part of an organism acquired during fetal development and present at birth (but not necessarily hereditary) which is hypothesized to be harmful for the organism. Albert Goldfain congenital malformation http://code.google.com/p/ogms/issues/detail?id=28 creation date: 2010-03-31T04:51:11Z congenital disorder OGMS:0000090 A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=35 creation date: 2010-03-31T04:51:11Z treatment OGMS:0000091 A processual entity during which a patient participating in a disease course gradually returns to participating in a canonical life course. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=35 creation date: 2010-03-31T04:51:11Z convalescence OGMS:0000092 A process which has as parts all the processes in which a given organism is participant. Albert Goldfain Richard Scheuermann Sagar Jain http://code.google.com/p/ogms/issues/detail?id=38 creation date: 2010-03-31T04:51:11Z EDIT: 10 NOV 2015 life course OGMS:0000093 A hypothesis about some future part of a disease course. Albert Goldfain http://code.google.com/p/ogms/issues/detail?id=35 creation date: 2010-03-31T12:42:23Z prognosis OGMS:0000094 A disease course with an acute onset Albert Goldfain http://code.google.com/p/ogms/wiki/Meeting_notes_20100513 creation date: 2010-07-19T11:57:44Z 10212020 for definition use http://purl.obolibrary.org/obo/PATO_0000389 acute disease course OGMS:0000095 A bodily process caused by some disorder that results in recruitment of leukocytes into a localized tissue site, typically causing localized pain and swelling. Albert Goldfain Richard Scheuermann Sagar Jain http://code.google.com/p/ogms/wiki/Meeting_notes_20100513 creation date: 2010-07-19T11:57:44Z Updated: 10 NOV 2015 inflammatory process OGMS:0000096 A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient Albert Goldfain Sagar Jain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z editor date: 2017-04-18 health care process OGMS:0000097 A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role. The health care provider role and patient are realized during the health care encounter Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z health care encounter OGMS:0000098 TODO Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z 09/16/2020 Is this same as admission? Is this the same as inpatient encounter? hospitalization OGMS:0000099 TODO Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z outpatient encounter OGMS:0000100 A health care encounter involving a patient who has been admitted to a health care facility and remains in a hospital facility for at least one night. Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z inpatient encounter OGMS:0000101 A health care encounter in which care is provided for undifferentiated and unscheduled patients with illnesses or injuries requiring immediate medical attention. Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/a2dbc2ed1dff99d6 creation date: 2011-02-21T09:57:44Z emergency department encounter OGMS:0000102 A disorder that involves some structural damage that is immediately caused by a catastrophic external force. At the scale of organism (as opposed to the cellular scale or the population scale), an injury is typically the result of a catastrophic event. Consider the implications of making 'injury' a subtype of 'disorder'. Note: Adopted subtype of disorder, and injury can occur at the scale of organism down to cellular level. Albert Goldfain Sagar Jain http://groups.google.com/group/ogms-discuss/browse_thread/thread/ca0ad373f27774c5 OGMS call adoption- 16 SEPT 2015 https://docs.google.com/document/d/1iiV1-fTS7BUUSzDw3N_Afx42698YWf54-FOTY2NkAxo/edit creation date: 2011-09-20T09:57:44Z edited date: 30 SEPT 2015 injury OGMS:0000103 A planned process whose completion is hypothesized by a health care provider to reduce the risk of developing a disorder or the signs and symptoms of a disorder. Whether or not 'prophylaxis' and 'treatment' classes are disjoint is an open question. Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/e42bde79218ee34e creation date: 2011-09-20T09:57:44Z disease prophylaxis OGMS:0000104 A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output). Albert Goldfain http://groups.google.com/group/ogms-discuss/browse_thread/thread/2a7008f311fac766/e7de486c94dfd82e creation date: 2011-09-20T09:57:44Z diagnostic process OGMS:0000105 A disease stage which is preceded by a remission and characterized by the return of a manifestation of a disease. A pathological bodily process which is part of a disease couse that occurs after an incomplete remission and that is similar to earlier parts of the disease course. Albert Goldfain Richard Scheuermann Sagar Jain recurrent http://code.google.com/p/ogms/issues/detail?id=73 10 NOV 2015 relapse OGMS:0000106 A disease stage which is characterized by the lack of a manifestation of a disease A part of a disease course in which the extent or rate of change of the signs and symptoms of a disorder has decreased. Albert Goldfain Richard Scheuermann Sagar Jain http://code.google.com/p/ogms/issues/detail?id=73 10 NOV 2015 remission OGMS:0000107 A planned process that has the objective to support the objective of a health care process without directly involving the treatment, diagnosis, or prevention of disease or injury of a patient. 2017-04-18 Sagar Jain ancillary health care process OGMS:0000108 A health care process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies. creation: 16MAY2017 Sagar Jain health care process assay OGMS:0000109 A health care process which results in physical changes in a specified input material creation: 16MAY2017 Sagar Jain health care process biomaterial transformation OGMS:0000110 A health care process that produces output from input data creation: 16MAY2017 Sagar Jain health care process data transformation OGMS:0000111 A treatment whose completion is hypothesized by a health care provider to prevent the signs and symptoms of a disorder or pathological process. Creation date: 2018-11-27 prophylactic treatment OGMS:0000112 A treatment whose completion is hypothesized by a health care provider to eliminate a disorder or to alleviate the signs and symptoms of a disorder or pathological process. Creation data: 2018-11-27 therapeutic procedure OGMS:0000113 A therapeutic procedure that uses synthetic or naturally-occurring chemicals creation date: 2018-11-27 chemotherapy procedure OGMS:0000114 A therapeutic procedure that uses immune system derived entities. creation date: 2018-11-27 immunotherapy procedure OGMS:0000115 A therapeutic procedure that uses physical conditioning creation date: 2018-11-27 physical therapy procedure OGMS:0000116 A therapeutic procedure that uses radiation. creation date: 2018-11-27 radiation therapy procedure OGMS:0000117 A disease stage characterized by the lack of symptoms associated with a given disease creation date: 2018-11-27 asymptomatic OGMS:0000118 A disease stage that marks the beginning of a disease creation date 2018-11-27 onset OGMS:0000119 A disease stage with a rapid unfolding of signs and symptoms creation date 2018-11-27 acute onset OGMS:0000120 A remission which is characterized by a prolonged lack of all manifestations of a disease complete remission OGMS:0000121 A remission which is characterized by a prolonged lack of some manifestations of a disease partial remission OGMS:0000122 A quality in which complete clearance of the disorder is attained; however, physiological 'memory' may persist creation date: 2018-11-27 recovered from disease OGMS:0000123 A data item that is about a patient and is the specified output of a health care process assay or diagnostic process creation date: 2018-11-27 clinical data item OGMS:0000124 A health care encounter that is regularly scheduled for the purpose of health monitoring. routine clinical visit routine health care encounter OGMS:0000125 A health care encounter that is scheduled for the purpose of assessing a known set of specific issues follow-up clinical visit follow-up health care encounter OGMS:0000126 A congenital disorder arising as a result of an infectious process congenital infection OGMS:0000127 A congenital disorder arising as a result of a drug exposure causing an anatomical abnormality drug induced congenital malformation OGMS:0000128 A pathological bodily process that occurs in the fetus during fetal development congenital process OGMS:0000129 An abnormal material entity that is part of a patient and hypothesized to be clinically relevant. Example: an abnormal growth, an inflammatory infiltrate, swollen tissue, distension physical sign OGMS:0000130 The process in which an allergic disease unfolds. allergic disease process OGMS:0000131 The process in which cancer unfolds cancer process OGMS:0000132 The process in which an autoimmune disease unfolds. autoimmune disease process OGMS:0000133 progression stage OGMS:0000134 cancer progression stage OGMS:0000135 A cancer progression stage characterized by abnormal cellular growth contained within normal tissue boundaries (e.g. carcinoma in situ). cancer progression stage 0 OGMS:0000136 A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass. cancer progression stage I OGMS:0000137 A cancer progression stage characterized by abnormal cellular growth that extends well beyond normal local tissue boundaries as a contiguous mass. cancer progression stage II OGMS:0000138 A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass and includes metastasis to one or more regional draining lymph nodes. cancer progression stage III OGMS:0000139 A cancer progression stage characterized by abnormal cellular growth that extends through normal local tissue boundaries as a contiguous mass and includes metastasis to other distant tissues besides lymph nodes. cancer progression stage IV OGMS:0000140 The process in which an infectious disease unfolds infectious disease process OGMS:0000141 An abnormal processual entity occuring in a patient that is hypothesized to be clinically relevant. processual sign OGMS:0000142 An abnormal observable quality of a part of a patient that is hypothesized to be clinically relevant. Example: the color of a rash; the shape of a melanoma qualitative sign OGMS:0000143 A therapeutic procedure in which a body part is transferred into a organism transplantation OGMS:0000144 A transplantation in which the body part is a non-fluid tissue solid organ transplant OGMS:0000145 A transplantation in which the body part is a bodily fluid transfusion OGMS:0000146 A disorder of some macroscopic part of a tissue tissue disorder OGMS:0000147 A tissue disorder that has resulted from a dysregulation of cell proliferation leading to a net increase in mass neoplasm OGMS:0000148 A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease. Originally OBIB_0000026 medication role PNADO:0000003 General symptom PNADO:0000003 PNADO:0000005 Abnormal pulmonary examination PNADO:0000005 C0025086 PNADO:0000007 Medical imaging PNADO:0000007 Any stepwise set of actions. (NCI) UMLS:C2700391 PNADO:0000008 Procedure PNADO:0000008 Having to do with the heart and lungs. (NCI) Outcomes that describe an individual's cardiac, pulmonary, circulatory, or tissue perfusion status (NOC) UMLS:C0553534 PNADO:0000009 Cardiopulmonary PNADO:0000009 UMLS:C3553459 PNADO:0000012 Recurrent cough PNADO:0000012 An abnormal sound similar to snoring heard on auscultation of the bronchial airways, suggesting a partial obstruction due to thick secretions, a muscular spasm, or a neoplasm. (NCI) UMLS:C0035508 rhonchi sound rhonchorous sound rhonchus sound PNADO:0000013 Rhonchi PNADO:0000013 UMLS:C2887070 PNADO:0000014 Whooping cough due to Bordetella parapertussis without pneumonia PNADO:0000014 PNADO:0000015 Occasional cough PNADO:0000015 Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. (MSH) UMLS:C0007222 PNADO:0000016 Cardiovascular disease PNADO:0000016 PNADO:0000019 Mild sputum production PNADO:0000019 PNADO:0000020 Breath sounds diffusely PNADO:0000020 PNADO:0000021 Elevation of hemidiaphragm PNADO:0000021 PNADO:0000022 Moderate diarrhea PNADO:0000022 PNADO:0000023 Severe obstructive lung disease PNADO:0000023 PNADO:0000025 H5N1 infection PNADO:0000025 UMLS:C0860045 PNADO:0000026 Multilobar pneumonia PNADO:0000026 PNADO:0000027 Severe structural lung disease PNADO:0000027 Polymicrobial pneumonia was defined as pneumonia due to more than one pathogen. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334753/) PNADO:0000029 Polymicrobial pneumonia PNADO:0000029 PNADO:0000030 Multifocal pneumonia PNADO:0000030 UMLS:C2183399 PNADO:0000031 difficult to rouse PNADO:0000031 PNADO:0000032 Mild respiratory distress PNADO:0000032 PNADO:0000033 Vomiting everything PNADO:0000033 UMLS:C0235150 Feeling Cold PNADO:0000035 Feeling cold PNADO:0000035 UMLS:C0241137 pale skin PNADO:0000036 Pallor of skin PNADO:0000036 PNADO:0000037 Little urine output PNADO:0000037 A way of contracting a disease through interactions with an infected person in the same residence. (NCI) UMLS:C3640861 Household Contact PNADO:0000038 Household contact PNADO:0000038 PNADO:0000039 Workplace contact PNADO:0000039 Inflammation of the mucous membrane lining the nose due to infection. (NCI UMLS:C0009443 PNADO:0000077 Coryza PNADO:0000077 UMLS:C0086066 PNADO:0000080 Acute coryza PNADO:0000080 UMLS:C0748649 PNADO:0000081 Shortness of breath rest PNADO:0000081 PNADO:0000082 Severe shortness of breath rest PNADO:0000082 PNADO:0000083 Blue face PNADO:0000083 PNADO:0000108 Purulent tracheal secretion PNADO:0000108 PNADO:0000109 Purulent tracheobronchial secretion PNADO:0000109 UMLS:C0855833 PNADO:0000111 Abnormal tracheal aspiration PNADO:0000111 UMLS:C0855834 PNADO:0000112 Normal tracheal aspiration PNADO:0000112 An individual living system that may be unicellular or made up of many billions of cells like humans. UMLS:C0029235 PNADO:0000123 Organism PNADO:0000123 UMLS:C2887071 PNADO:0000211 Whooping cough due to Bordetella parapertussis with pneumonia PNADO:0000211 UMLS:C2887073 PNADO:0000212 Whooping cough due to other Bordetella species with pneumonia PNADO:0000212 ICD10CM:A37.91 UMLS:C2887076 PNADO:0000213 Whooping cough, unspecified species with pneumonia PNADO:0000213 UMLS:C1390423 PNADO:0000214 Whooping cough; Bordetella bronchiseptica, with pneumonia (manifestation) PNADO:0000214 UMLS:C1390426 PNADO:0000215 Whooping cough; Bordetella parapertussis, with pneumonia (manifestation) PNADO:0000215 UMLS:C1390427 PNADO:0000216 Whooping cough; Bordetella pertussis, with pneumonia (manifestation) PNADO:0000216 PNADO:0000217 Focal chest signs PNADO:0000217 UMLS:C0859927 PNADO:0000230 Increased work of breathing PNADO:0000230 PNADO:0000231 Tracheal aspiration finding PNADO:0000231 UMLS:C0425488 PNADO:0000232 Panting respiration PNADO:0000232 UMLS:C0743323 PNADO:0000237 Acute dyspnea PNADO:0000237 PNADO:0000238 Progressive respiratory distress PNADO:0000238 PNADO:0000239 Severe respiratory distress PNADO:0000239 A respiratory system symptom consisting of the matter discharged from the air passages in diseases of the lungs, bronchi, or upper respiratory tract that contains mucus and often pus, blood, fibrin, or bacterial products. (SYMP) UMLS:C0242104 sputum PNADO:0000259 Sputum production PNADO:0000259 Any of several immunoassay methods that use an enzyme covalently linked to an antigen or antibody as a label; the most common types are enzyme-linked immunosorbent assay (ELISA) and enzyme-multiplied immunoassay technique (EMIT). (NCI) C0086231 EIA PNADO:0000360 Enzyme immunoassay PNADO:0000360 Pie chart displaying the sensitivity of a set of microbes to one agent or condition. (MSH) UMLS:C1720786 PNADO:0000361 Antibiogram PNADO:0000361 PNADO:0000364 Respiratory tract specimen gram stain and culture PNADO:0000364 PNADO:0000365 Microbiological test for pleural fluid examination PNADO:0000365 The neurologic status characterized by the occurrence of a loss of the ability to perceive and respond. (NCI) UMLS:C0041657 PNADO:0000541 Unconsciousness state PNADO:0000541 UMLS:C1096625 PNADO:0000616 Mental exhaustion PNADO:0000616 UMLS:C2037120 PNADO:0000618 Sudden exhaustion PNADO:0000618 A condition characterized by excessive fatigue and lack of energy, increasing irritability, and feelings of demoralization. Persons who experience this condition are not at an increased risk for cancer. (NCI) PNADO:0000619 Vital exhaustion PNADO:0000619 UMLS:C0598937 PNADO:0000620 Nervous exhaustion PNADO:0000620 UMLS:C2219846 PNADO:0000672 Malaise worse in evening PNADO:0000672 UMLS:C2219845 PNADO:0000673 Malaise worse in morning PNADO:0000673 PNADO:0000676 Severe malaise PNADO:0000676 PNADO:0000679 Inability to drink PNADO:0000679 PNADO:0000680 Inability to take oral medication PNADO:0000680 UMLS:C0015544 PNADO:0000682 Failure to thrive PNADO:0000682 PNADO:0000698 Severe myalgia PNADO:0000698 intense chest pain PNADO:0000762 Severe chest pain PNADO:0000762 PNADO:0000770 Arterial blood gas PNADO:0000770 PNADO:0000777 Bronchoscopic aspirations PNADO:0000777 A procedure in which cells are taken from the inside of the airways that lead to the lungs. A bronchoscope (a thin, tube-like instrument with a light and a lens for viewing) is inserted through the nose or mouth into the lungs. A mild salt solution is washed over the surface of the airways to collect cells, which are then looked at under a microscope. Bronchial washing is used to find infections. It may also help find cancer or changes in cells that may lead to cancer. (NCI) UMLS:C0396473 PNADO:0000778 Bronchoscopic irrigation PNADO:0000778 PNADO:0000779 Endotracheal aspirate sample PNADO:0000779 UMLS:C3897988 Partial Pressure Arterial Oxygen to Fraction Inspired Oxygen Ratio Measurement PNADO:0000781 PaO2/FiO2 PNADO:0000781 An x-ray of the structures inside the chest. An x-ray is a type of high-energy radiation that can go through the body and onto film, making pictures of areas inside the chest, which can be used to diagnose disease. (NCI) C3842377 Chest radiograph Chest x-ray Plain chest X-ray Radiography of chest PNADO:0000783 Chest radiography PNADO:0000783 An imaging technique for examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis. (NCI) Tomography using x-ray transmission and a computer algorithm to reconstruct the image. (MSH) SNOMEDCT_US:77477000 UMLS:C0040405 CT chest Computerised tomograph scan Computerized tomograph scan PNADO:0000784 CT scan PNADO:0000784 PNADO:0000786 Lateral chest radiograph PNADO:0000786 PNADO:0000787 Lateral upright chest radiograph PNADO:0000787 PNADO:0000788 Portable radiography PNADO:0000788 PNADO:0000789 Posteroanterior chest radiograph PNADO:0000789 PNADO:0000793 Homogeneous opacity obscuring vessel PNADO:0000793 PNADO:0000794 Air bronchogram PNADO:0000794 PNADO:0000795 Ill-defined PNADO:0000795 PNADO:0000796 Fluffy opacity PNADO:0000796 PNADO:0000797 Air alveologram PNADO:0000797 PNADO:0000798 Patchy opacity PNADO:0000798 Airspace nodules are irregularly marginated nodular opacities with air bronchograms that tend to measure 8 mm in diameter. PNADO:0000800 Airspace nodule PNADO:0000800 PNADO:0000801 Microbiological test for respiratory tract specimen examination PNADO:0000801 UMLS:C0729856 PNADO:0000802 Antigen test PNADO:0000802 PNADO:0000803 Microbiological test for blood examination PNADO:0000803 blood testing PNADO:0000804 Blood examination PNADO:0000804 C2242629 PNADO:0000805 Pleural fluid analysis PNADO:0000805 expectorated sputum samples collected for culture sputum culture PNADO:0000806 Respiratory tract specimen examination PNADO:0000806 C0201284 PNADO:0000810 Fluorescent antibody test PNADO:0000810 PNADO:0000811 Microimmunofluorescence serologic test PNADO:0000811 PNADO:0000812 Blood samples drawn for culture PNADO:0000812 Examination of urine by chemical, physical, or microscopic means. Routine urinalysis usually includes performing chemical screening tests, determining specific gravity, observing any unusual color or odor, screening for bacteriuria, and examining the sediment microscopically. (MSH) SNOMEDCT_US:167217005 UMLS:C0042014 PNADO:0000813 Urine examination PNADO:0000813 PNADO:0000814 Urinary antigen tests for legionella pneumophila PNADO:0000814 UMLS:C2721555 legionella UAT legionella urinary antigen test PNADO:0000816 Legionella urinary antigen PNADO:0000816 pneumococcal UAT PNADO:0000818 Streptococcus pneumoniae urinary antigen PNADO:0000818 PNADO:0000820 Elevated blood urea nitrogen PNADO:0000820 UMLS:C0728725 PNADO:0000824 Low PH PNADO:0000824 PNADO:0000825 Respiratory lab test finding PNADO:0000825 Measurements of rates of airflow during a forced vital capacity determination; includes maximal and peak expiratory flow rate measurement. (CSP) UMLS:C0678216 PNADO:0000826 Finding of respiratory airflow PNADO:0000826 PNADO:0000829 Patient infection exposure PNADO:0000829 PNADO:0000830 General clinical finding PNADO:0000830 Endemic exposure PNADO:0000831 Infectious contact PNADO:0000831 UMLS:C1868981 PNADO:0000832 Invasive mechanical ventilation PNADO:0000832 PNADO:0000833 History of recent travel PNADO:0000833 Any of the four periods into which the year is divided by the equinoxes and solstices. (NCI) UMLS:C0036497 PNADO:0000834 Seasons PNADO:0000834 The season between the autumnal equinox and the winter solstice. (NCI) UMLS:C0238715 PNADO:0000835 Automn PNADO:0000835 The season between the vernal equinox and the summer solstice. (NCI) UMLS:C0241232 PNADO:0000836 Spring PNADO:0000836 The season between the summer solstice and the autumnal equinox. (NCI) UMLS:C0241301 PNADO:0000837 Summer PNADO:0000837 The season between the winter solstice and the vernal equinox. (NCI) UMLS:C0241737 PNADO:0000838 Winter PNADO:0000838 UMLS:C3532585 PNADO:0000839 History of recent air travel PNADO:0000839 UMLS:C3532583 PNADO:0000840 History of recent cruise travel PNADO:0000840 PNADO:0000844 Date of birth PNADO:0000844 Race and ethnicity information:Find:Pt:^Patient:Doc (MSH) UMLS:C4484101 PNADO:0000845 Race and ethnicity information PNADO:0000845 Describes socially-constructed identity of male or female. (MSH) UMLS:C1287419 PNADO:0000846 Gender finding PNADO:0000846 PNADO:0000847 Height finding PNADO:0000847 PNADO:0000849 Weight finding PNADO:0000849 PNADO:0000852 Pleural fluid gram stain and culture PNADO:0000852 PNADO:0000854 Pleural fluid cell count differential PNADO:0000854 PNADO:0000857 Pleural fluid cytologic analysis PNADO:0000857 PNADO:0000860 Multilobar disease PNADO:0000860 PNADO:0000870 Pleural fluid chemistries PNADO:0000870 PNADO:0000872 Blood biomarkers test PNADO:0000872 A material entity with a pathogenic disposition. (IDO) http://purl.org/cpr/pathogen Etiologic agent Infectious agent PNADO:0000874 Pathogen PNADO:0000874 A person who participates in a healthcare act while playing the patient role. Directly corresponds to the Patient and MedicalPatient classes in GALEN / Cyc. (CPR) http://purl.org/cpr/patient PNADO:0000876 Patient PNADO:0000876 A peptide prohormone precursor of CALCITONIN. It is normally present at low levels in serum, but is released into the bloodstream, primarily from neuroendocrine cells in the lungs and intestines, in response to INFLAMMATION and BACTERIAL INFECTIONS. It is a diagnostic marker for BACTEREMIA. (MSH) C0072027 PNADO:0000877 Procalcitonin PNADO:0000877 UMLS:C0011731 Desulfovibrio species Genus Desulfovibrio Genus Desulfovibrio (organism) PNADO:0000955 Desulfovibrio PNADO:0000955 UMLS:C3061918 PNADO:0000996 Diplorickettsia PNADO:0000996 PNADO:0001087 Legionella pneumophila subsp. pneumophila str. philadelphia 1 PNADO:0001087 PNADO:0001139 Vaccination status PNADO:0001139 PNADO:0001170 History of exposure to rabbits PNADO:0001170 PNADO:0001173 History of exposure to birds PNADO:0001173 PNADO:0001174 History of exposure to bat or bird dropping PNADO:0001174 PNADO:0001176 History of hotel stay PNADO:0001176 Severe CAP PNADO:0001229 Severe community-acquired pneumonia PNADO:0001229 PNADO:0001230 Slowly resolving pneumonia PNADO:0001230 Infection of the lung often accompanied by inflammation that is acquired through an interaction within a healthcare institution often through a therapeutic experience (e.g., use of catheters or ventilators). (MSH) UMLS:C1443237 PNADO:0001231 Healthcare associated pneumonia PNADO:0001231 PNADO:0001234 Human / Person PNADO:0001234 CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia[1] and infection of any site. (Wikipedia) CRB65 PNADO:0001239 CURB-65 PNADO:0001239 PNADO:0001241 SMART-COP is an acronym for Systolic blood pressure, Multilobar infiltrates, Albumin, Respiratory rate, Tachycardia, Confusion, Oxygen and pH SMART-COP PNADO:0001241 The left ventricular pressure during diastole. (VSO) PNADO:0001248 Diastolic left ventricular pressure PNADO:0001248 UMLS:C0154660 PNADO:0001264 Central nervous system abscess PNADO:0001264 A plasma protein that circulates in increased amounts during inflammation and after tissue damage. C-Reactive Protein measured by more sensitive methods often for coronary heart disease risk assessment is referred to as High Sensitivity C-Reactive Protein (hs-CRT). (MSH) UMLS:C0006560 PNADO:0001324 C-reactive protein PNADO:0001324 PNADO:0002345 Chronic neurological disease PNADO:0002345 Hepatic necrosis, inflammation, or scarring due to any cause that persists for more than 6 months. Manifestations may include signs and symptoms of cholestasis, portal hypertension, and/or abnormal liver function tests. (NCI) SNOMEDCT_US_2020_03_01:328383001 UMLS:C0341439 Chronic liver disease (disorder) PNADO:0002346 Chronic liver disease PNADO:0002346 PNADO:0009999 Differential diagnosis for pneumonia PNADO:0009999 Confusion is a neurological and physiological symptom characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively. (SYMP) HP:0001289 UMLS:C0009676 SYMP:0000016 confusion SYMP: 2020/02/26 SYMP:0000016 Delirium is a neurological and physiological symptom characterized by a mental disturbance characterized by confusion, disordered speech, and hallucinations. (SYMP) UMLS:C0011206 SYMP:0000021 delirium SYMP: 2020/02/26 SYMP:0000021 UMLS:C0233407 SYMP:0000023 disorientation SYMP: 2020/02/26 SYMP:0000023 Lethargy is a fatigue characterized as abnormal drowsiness. (SYMP) UMLS:C0023380 SYMP:0000075 lethargy SYMP: 2020/02/26 SYMP:0000075 symptoms SYMP:0000130 severe headache SYMP: 2020/02/26 SYMP:0000130 fecal SYMP:0000146 feces and droppings symptom SYMP: 2020/02/26 SYMP:0000146 SNOMEDCT_US:60119000 UMLS:C0392674 SYMP:0000186 exhaustion SYMP: 2020/02/26 SYMP:0000186 Afebrile is a fever that is characterized as the state of being free from fever. symptoms SYMP:0000207 afebrile SYMP: 2020/02/26 SYMP:0000207 Afebrile is a fever that is characterized as the state of being free from fever. URL:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=afebrile Acute diarrhea is defined as the abrupt onset of 3 or more loose stools per day and lasts no longer than 14 days UMLS:C0151594 SYMP:0000228 hemorrhagic diarrhea SYMP: 2020/02/26 SYMP:0000228 Cyclic fever is a fever that occurs during periodic episodes. SYMP:0000884 recurrent fever symptoms intermittent fever SYMP:0000243 cyclic fever SYMP: 2020/02/26 SYMP:0000243 Cyclic fever is a fever that occurs during periodic episodes. url:http://en.wikipedia.org/wiki/Fever#Types url:http://www.wrongdiagnosis.com/sym/cyclic_fever_in_children.htm SYMP:0000259 dry hacking cough SYMP: 2020/02/26 SYMP:0000259 A condition in which a person is so tired or weak that he or she is unable to do anything. (NCI) SNOMEDCT_US:84946008 UMLS:C0277794 Prostration SYMP:0000279 extreme exhaustion SYMP: 2020/02/26 SYMP:0000279 SYMP:0000280 extreme fatigue SYMP: 2020/02/26 SYMP:0000280 SNOMEDCT_US:71587006 UMLS:C0234539 SYMP:0000327 tetanic convulsion SYMP: 2020/02/26 SYMP:0000327 SYMP:0000328 mild tetanic convulsion SYMP: 2020/02/26 SYMP:0000328 Runny nose is a nose symptom characterized by an excessive mucous secretion from the nose. (SYMP) SYMP:0000372 runny nose SYMP: 2020/02/26 SYMP:0000372 cervicalgia SYMP:0000384 neck symptom SYMP: 2020/02/26 SYMP:0000384 SYMP:0000387 head symptom SYMP: 2020/02/26 SYMP:0000387 UMLS:C0497340 nasal symptom SYMP:0000388 nose symptom SYMP: 2020/02/26 SYMP:0000388 Hyperthermia is a fever that involves an exceptionally high fever especially when induced artificially for therapeutic purposes. symptoms SYMP:0000409 hyperthermia SYMP: 2020/02/26 SYMP:0000409 Hyperthermia is a fever that involves an exceptionally high fever especially when induced artificially for therapeutic purposes. url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hyperthermia SYMP:0000410 neurological and physiological symptom SYMP: 2020/02/26 SYMP:0000410 Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain. HP:0001279 SNOMEDCT_US:271594007 UMLS:C0039070 fainting syncope SYMP:0000445 faint SYMP: 2020/02/26 SYMP:0000445 Faint is a alteration of consciousness characterized by a loss of consciousness because of a temporary decrease in the blood supply to the brain. URL:http://www.merriam-webster.com/dictionary/fainting Bloody sputum (spitting up blood or bloody mucus) can come from common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung. Bloody sputum is a sputum that consists of blood or bloody mucus discharged from the air passages caused by common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung. (SYMP) SYMP:0000447 Bloody sputum (spitting up blood or bloody mucus) can come from common forms of infection in the lungs and airways, such as acute bronchitis or pneumonia. Bloody sputum can also come from cancer of the lung. bloody sputum SYMP: 2020/02/26 SYMP:0000447 ICD9CM_2005:787 SyOID:5330 UMLS:C0159058 UMLS_ICD9CM_2005_AUI:A0284224 SYMP:0000459 digestive system symptom SYMP: 2020/02/26 SYMP:0000459 SYMP:0000473 nutrition, metabolism, and development symptom SYMP: 2020/02/26 SYMP:0000473 UMLS:C0159033 SYMP:0000480 nervous system symptom SYMP: 2020/02/26 SYMP:0000480 ICD9CM_2005:780.0 SyOID:7293 UMLS:C0234428 UMLS_ICD9CM_2005_AUI:A0389211 SYMP:0000482 alteration of consciousness SYMP: 2020/02/26 SYMP:0000482 ICD9CM_2005:788 SyOID:2134 UMLS:C0476293 UMLS_ICD9CM_2005_AUI:A0284245 SYMP:0000486 urinary system symptom SYMP: 2020/02/26 SYMP:0000486 ICD9CM_2005:782 ICD9CM_2005:782.9 SyOID:2103 UMLS:C0159037 UMLS_ICD9CM_2005_AUI:A0284146 UMLS_ICD9CM_2005_AUI:A0284161 symptoms SYMP:0000488 skin and integumentary tissue symptom SYMP: 2020/02/26 SYMP:0000488 Headache is a pain characterized by a pain in the head. ICD9CM_2005:784.0 SyOID:14723 UMLS:C0018681 UMLS_ICD9CM_2005_AUI:A0065994 cephalalgia symptoms SYMP:0000504 headache SYMP: 2020/02/26 SYMP:0000504 Headache is a pain characterized by a pain in the head. URL:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=headache ICD9CM_2005:786 SyOID:5868 UMLS:C0476271 UMLS_ICD9CM_2005_AUI:A0284200 SYMP:0000514 respiratory system and chest symptom SYMP: 2020/02/26 SYMP:0000514 Hemoptysis is a respiratory system and chest symptom characterized by an expectoration of blood from some part of the respiratory tract. (SYMP) ICD9CM_2005:786.3 SNOMEDCT_US:66857006 SyOID:15073 UMLS:C0019079 UMLS_ICD9CM_2005_AUI:A0067232 coughing up of blood expectoration of blood expectoration of blood-stained sputum haemoptysis SYMP:0000517 hemoptysis SYMP: 2020/02/26 SYMP:0000517 ICD9CM_2005:785 SyOID:2147 UMLS:C0159049 UMLS_ICD9CM_2005_AUI:A0284192 symptoms SYMP:0000528 cardiovascular system symptom SYMP: 2020/02/26 SYMP:0000528 An unpleasant sensation of irregular and/or forceful beating of the heart. (NCI) Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart, whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease. ICD9CM_2005:785.1 SyOID:16497 UMLS:C0030252 UMLS_ICD9CM_2005_AUI:A0004066 abnormal heart beats symptoms SYMP:0000530 palpitation SYMP: 2020/02/26 SYMP:0000530 Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart, whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease. url:http://en.wikipedia.org/wiki/Palpitation url:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=palpitation UMLS:C4048158 SYMP:0000596 Convulsion SYMP: 2020/02/26 SYMP:0000596 ICD9CM_2005:784 SyOID:7123 UMLS:C0476247 UMLS_ICD9CM_2005_AUI:A0284173 symptoms SYMP:0000597 head and neck symptom SYMP: 2020/02/26 SYMP:0000597 ICD9CM_2005:786.0 SyOID:7239 UMLS:C0159053 UMLS_ICD9CM_2005_AUI:A0284202 SYMP:0000598 respiratory abnormality SYMP: 2020/02/26 SYMP:0000598 Fever is a neurological and physiological symptom characterized by a rise of body temperature above the normal whether a natural response (as to infection) or artificially induced for therapeutic reasons. ICD9CM_2005:780.6 SyOID:776 UMLS:C0015967 UMLS_ICD9CM_2005_AUI:A0058972 pyrexia symptoms SYMP:0000613 fever SYMP: 2020/02/26 SYMP:0000613 Fever is a neurological and physiological symptom characterized by a rise of body temperature above the normal whether a natural response (as to infection) or artificially induced for therapeutic reasons. URL:http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=fever symptoms SYMP:0000630 frontal headache SYMP: 2020/02/26 SYMP:0000630 SYMP:0000664 yellow exudate from nose SYMP: 2020/02/26 SYMP:0000664 symptoms SYMP:0000671 sudden onset of fever SYMP: 2020/02/26 SYMP:0000671 Acute diarrhea is a diarrhea with either or both a rapid onset or a short course. (SYMP) UMLS:C0740441 SYMP:0000675 acute diarrhea SYMP: 2020/02/26 SYMP:0000675 symptoms SYMP:0000684 bifrontal headache SYMP: 2020/02/26 SYMP:0000684 SYMP:0000738 yellowish green diarrhea SYMP: 2020/02/26 SYMP:0000738 SYMP:0000741 nasal bleeding SYMP: 2020/02/26 SYMP:0000741 Transient fever is a fever that is characterized as a rise of body temperature above the normal that is sustained for only a short period of time. symptoms SYMP:0000878 transient fever SYMP: 2020/02/26 SYMP:0000878 Transient fever is a fever that is characterized as a rise of body temperature above the normal that is sustained for only a short period of time. url:http://en.wiktionary.org/wiki/fever url:http://en.wiktionary.org/wiki/transient Low-grade fever is a fever that does not exceed 38.5 degree centrigrade. lschriml 2010-10-15T11:28:26Z symptoms SYMP:0000879 low-grade fever SYMP: 2020/02/26 SYMP:0000879 Low-grade fever is a fever that does not exceed 38.5 degree centrigrade. url:http://www.wrongdiagnosis.com/sym/low_grade_fever.htm Prolonged fever is a fever that persists over a prolonged period of time. lschriml 2010-10-15T11:28:26Z symptoms SYMP:0000880 prolonged fever SYMP: 2020/02/26 SYMP:0000880 Prolonged fever is a fever that persists over a prolonged period of time. url:http://www.wrongdiagnosis.com/sym/prolonged_fever.htm Mild fever is a fever that occurs in a mild form. lschriml 2010-10-15T11:28:26Z symptoms SYMP:0000881 mild fever SYMP: 2020/02/26 SYMP:0000881 Mild fever is a fever that occurs in a mild form. url:http://www.wrongdiagnosis.com/sym/mild_fever.htm High fever is a fever that involved an elevated temperature. lschriml 2010-10-15T11:28:26Z symptoms SYMP:0000882 high fever SYMP: 2020/02/26 SYMP:0000882 High fever is a fever that involved an elevated temperature. url:http://www.wrongdiagnosis.com/sym/high_fever.htm Very high fever is a fever that involves extremely high temperatures. lschriml 2010-10-15T11:28:26Z symptoms SYMP:0000883 very high fever SYMP: 2020/02/26 SYMP:0000883 Very high fever is a fever that involves extremely high temperatures. url:http://www.wrongdiagnosis.com/sym/very_high_fever.htm Hyperpyrexia is a fever with an extreme elevation of body temperature greater than or equal to 41.5 degree Celsius (106.7 degree Fahrenheit). lschriml 2010-10-15T11:38:55Z symptoms SYMP:0000886 hyperpyrexia SYMP: 2020/02/26 SYMP:0000886 Hyperpyrexia is a fever with an extreme elevation of body temperature greater than or equal to 41.5 degree Celsius (106.7 degree Fahrenheit). url:http://en.wikipedia.org/wiki/Fever Pel-Epstein fever is a fever that is associated with Hodgkin's lymphoma where the fever alternates weekly from high to low. lschriml 2010-10-15T11:40:07Z symptoms SYMP:0000887 Pel-Epstein fever SYMP: 2020/02/26 SYMP:0000887 Pel-Epstein fever is a fever that is associated with Hodgkin's lymphoma where the fever alternates weekly from high to low. url:http://en.wikipedia.org/wiki/Fever Continuous fever is a fever where temperature remains above normal throughout the day and does not fluctuate more than 1 degree Celsius in 24 hours. lschriml 2010-10-15T11:42:19Z symptoms continued fever SYMP:0000888 continuous fever SYMP: 2020/02/26 SYMP:0000888 Continuous fever is a fever where temperature remains above normal throughout the day and does not fluctuate more than 1 degree Celsius in 24 hours. url:http://en.wikipedia.org/wiki/Fever#Types Remittent fever is a fever where the temperature remains above normal throughout the day and fluctuates more than 1degree Celsius in 24 hours. lschriml 2010-10-15T11:42:19Z symptoms SYMP:0000889 remittent fever SYMP: 2020/02/26 SYMP:0000889 Remittent fever is a fever where the temperature remains above normal throughout the day and fluctuates more than 1degree Celsius in 24 hours. url:http://en.wikipedia.org/wiki/Fever#Types Relapsing fever is a fever where the body temperature periodically rises and falls. lschriml 2010-10-15T11:46:03Z symptoms SYMP:0000890 doid/symp duplicate relapsing fever SYMP: 2020/02/26 SYMP:0000890 Relapsing fever is a fever where the body temperature periodically rises and falls. url:https://www.merckmanuals.com/professional/infectious-diseases/spirochetes/relapsing-fever A skin andintegumentary tissue symptom that is characterized by cold, moist and sticky skin. (SYMP) UMLS:C0235848 SYMP:0000894 cold clammy skin SYMP: 2020/02/26 SYMP:0000894 A skin andintegumentary tissue symptom that is characterized by cold, moist and sticky skin. (SYMP) url:http://www.merriam-webster.com/medlineplus/clammy Role played by people who participate in clinical activities (typically Nurse, Physician / Doctor,etc.) clinician role CPRO: 2013/04/24 A role placed by a professional who provides a medical service healthcare professional role CPRO: 2013/04/24 Role played by people who are the recipient of healthcare services patient role CPRO: 2013/04/24 Role played by physicians who participate in clinical activities physician role CPRO: 2013/04/24 The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz. (MSH) UMLS:C0041618 echography sonography ultrasonography RID:10326 ultrasound RADLEX: 2020/11/25 RID:10326 RID:10606 CT scan mode RADLEX: 2020/11/25 RID:10606 CT scanned projection radiograph scout view surview topogram RID:10607 CT projection radiograph RADLEX: 2020/11/25 RID:10607 spiral scan mode RID:10613 helical scan mode RADLEX: 2020/11/25 RID:10613 step-and-shoot scan mode RID:10615 axial scan mode RADLEX: 2020/11/25 RID:10615 RID:10903 A-mode ultrasound RADLEX: 2020/11/25 RID:10903 RID:10904 B-mode ultrasound RADLEX: 2020/11/25 RID:10904 RID:10907 C-mode ultrasound RADLEX: 2020/11/25 RID:10907 RID:10908 Doppler mode RADLEX: 2020/11/25 RID:10908 RID:10913 harmonic ultrasound RADLEX: 2020/11/25 RID:10913 RID:10916 stimulated acoustic emission RADLEX: 2020/11/25 RID:10916 RID:10920 three dimensional ultrasound RADLEX: 2020/11/25 RID:10920 RID:10922 duplex ultrasound RADLEX: 2020/11/25 RID:10922 RID:10923 triplex ultrasound RADLEX: 2020/11/25 RID:10923 RID:10924 extended field of view ultrasound RADLEX: 2020/11/25 RID:10924 RID:10926 4 dimensional ultrasound RADLEX: 2020/11/25 RID:10926 RID:10930 volume imaging RADLEX: 2020/11/25 RID:10930 elasticity imaging RID:10932 elastography RADLEX: 2020/11/25 RID:10932 RID:10933 strain imaging RADLEX: 2020/11/25 RID:10933 Absence of air in the entire or part of a lung, such as an incompletely inflated neonate lung or a collapsed adult lung. Pulmonary atelectasis can be caused by airway obstruction, lung compression, fibrotic contraction, or other factors. (MSH) UMLS:C0004144 RID:28493 atelectasis RADLEX: 2020/11/25 RID:28493 Rounded atelectasis is rounded collapsed lung associated with invaginated fibrotic pleura and thickened and fibrotic interlobular septa. Most frequently, it is the consequence of an asbestos-induced exudative pleural effusion with resultant pleural scarring, but it may occur with any cause of pleural fibrosis. On chest radiographs, rounded atelectasis appears as a mass abutting a pleural surface, usually in the posterior part of a lower lobe. Distorted vessels have a curvilinear disposition as they converge on the mass (the comet tail sign). The degree of lobar retraction depends on the volume of atelectatic lung. It is almost invariably associated with other signs of pleural fibrosis (eg, blunting of costophrenic angle). (Fleischner Society) UMLS:C2062952 folded lung folded lung syndrome helical atelectasis pleuroma round atelectasis RID:28494 rounded atelectasis RADLEX: 2020/11/25 RID:28494 Linear atelectasis refers to a focal area of subsegmental atelectasis that has a linear shape. Linear atelectasis may appear to be horizontal, oblique or perpendicular and is very common. It usually occurs as a consequence of subsegmental bronchial obstruction and can resolve as quickly as it occurs. (Radiopaedia) UMLS:C0264495 discoid atelectasis platelike atelectasis RID:28513 linear atelectasis RADLEX: 2020/11/25 RID:28513 Opacity refers to any area that preferentially attenuates the x-ray beam and therefore appears more opaque than the surrounding area. It is a nonspecific term that does not indicate the size or pathologic nature of the abnormality. (Fleischner Society) RID:28530 opacity RADLEX: 2020/11/25 RID:28530 A CT scan finding in the lungs indicating the presence of hazy areas of attenuation in the air spaces. It is caused by interstitial fibrosis, alveolar collapse, edema, inflammation, or cancer with lepidic spread. (NCI) ground glass ground glass attenuation ground glass opacity ground-glass RID:28531 ground-glass opacity RADLEX: 2020/11/25 RID:28531 A parenchymal band is a linear opacity, usually 1-3 mm thick and up to 5 cm long that usually extends to the visceral pleura (which is often thickened and may be retracted at the site of contact). It reflects pleuroparenchymal fibrosis and is usually associated with distortion of the lung architecture. Parenchymal bands are most frequently encountered in individuals who have been exposed to asbestos. (Fleischner Society) RID:28532 parenchymal band RADLEX: 2020/11/25 RID:28532 RID:28533 parenchymal opacification RADLEX: 2020/11/25 RID:28533 A pseudoplaque is a pulmonary opacity contiguous with the visceral pleura formed by coalescent small nodules. It simulates the appearance of a pleural plaque. This entity is encountered most commonly in sarcoidosis, silicosis, and coal-worker's pneumoconiosis. (Fleischner Society) RID:28534 pseudoplaque RADLEX: 2020/11/25 RID:28534 This finding is a thin curvilinear opacity, 1-3 mm in thickness, lying less than 1 cm from and parallel to the pleural surface. It corresponds to atelectasis of normal lung if seen in the dependent posteroinferior portion of lung of a patient in the supine position and is subsequently shown to disappear on CT sections acquired with the patient prone. It may also be encountered in patients with pulmonary edema or fibrosis (other signs are usually present). Though described in the context of asbestosis, this finding is not specific for asbestosis. (Fleischner Society) RID:28536 subpleural curvilinear line RADLEX: 2020/11/25 RID:28536 UMLS:C0032227 RID:34539 pleural effusion RADLEX: 2020/11/25 RID:34539 Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection. (MSH) An abscess is a pocket of pus. You can get an abscess almost anywhere in your body. When an area of your body becomes infected, your body's immune system tries to fight the infection. White blood cells go to the infected area, collect within the damaged tissue, and cause inflammation. During this process, pus forms. Pus is a mixture of living and dead white blood cells, germs, and dead tissue. Bacteria, viruses, parasites and swallowed objects can all lead to abscesses. Skin abscesses are easy to detect. They are red, raised and painful. Abscesses inside your body may not be obvious and can damage organs, including the brain, lungs and others. Treatments include drainage and antibiotics. (MEDLINEPLUS) An inflammatory process characterized by the accumulation of pus within a newly formed tissue cavity which is the result of a bacterial, fungal, or parasitic infection or the presence of a foreign body. (NCI) HP:0025615 SNOMEDCT_US:128477000 UMLS:C0000833 abcess RID:3711 abscess RADLEX: 2020/11/25 RID:3711 RID:3712 tubo-ovarian abscess RADLEX: 2020/11/25 RID:3712 Accumulation of purulent exudates beneath the diaphragm, also known as upper abdominal abscess. It is usually associated with peritonitis or postoperative infections. (MeSH) C0038565 RID:3713 subphrenic abscess RADLEX: 2020/11/25 RID:3713 Presence of pus in a hollow organ or body cavity. (MeSH) UMLS:C0014009 RID:3714 empyema RADLEX: 2020/11/25 RID:3714 Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE. (MSH) UMLS:C0031039 RID:4872 pericardial effusion RADLEX: 2020/11/25 RID:4872 Consolidation refers to an exudate or other product of disease that replaces alveolar air, rendering the lung solid (as in infective pneumonia). (Fleischner Society) C0702116 RID:43255 consolidation RADLEX: 2020/11/25 RID:43255 Thin linear pulmonary opacities caused by fluid or cellular infiltration into the interstitium of the lungs. Kerley lines RID:43273 septal lines RADLEX: 2020/11/25 RID:43273 These are longer (at least 2cm and up to 6cm) unbranching lines coursing diagonally from the hila out to the periphery of the lungs. They are caused by distension of anastomotic channels between peripheral and central lymphatics of the lungs. Kerley A lines are less commonly seen than Kerley B lines. Kerley A lines are never seen without Kerley B or C lines also present. RID:43274 Kerley A lines RADLEX: 2020/11/25 RID:43274 These are short parallel lines at the lung periphery. These lines represent interlobular septa, which are usually less than 1 cm in length and parallel to one another at right angles to the pleura. They are located peripherally in contact with the pleura, but are generally absent along fissural surfaces. They may be seen in any zone but are most frequently observed at the lung bases at the costophrenic angles on the PA radiograph, and in the substernal region on lateral radiographs. Kerley B lines are seen in Congestive Heart Failure (CHF) and Interstitial Lung Diseases (ILD). RID:43275 Kerley B lines RADLEX: 2020/11/25 RID:43275 These are the least commonly seen of the Kerley lines. They are short, fine lines throughout the lungs, with a reticular appearance. They may represent thickening of anastomotic lymphatics or superimposition of many Kerley B lines. RID:43276 Kerley C lines RADLEX: 2020/11/25 RID:43276 A juxtaphrenic peak is a small triangular opacity based at the apex of the dome of a hemidiaphragm, associated with upper lobe volume loss of any cause (eg, postirradiation fibrosis or upper lobectomy). It is most readily appreciated on a frontal chest radiograph. The peak is caused by upward retraction of the inferior accessory fissure or an intrapulmonary septum associated with the pulmonary ligament. RID:43413 juxtaphrenic peak RADLEX: 2020/11/25 RID:43413 RID:45672 fungal microabscess RADLEX: 2020/11/25 RID:45672 RID:46009 semi-consolidation RADLEX: 2020/11/25 RID:46009 Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body. (MeSH) UMLS:C0016169 RID:4843 fistula RADLEX: 2020/11/25 RID:4843 RID:4844 rectovesical fistula RADLEX: 2020/11/25 RID:4844 colovesicular fistula RID:4845 colovesical fistula RADLEX: 2020/11/25 RID:4845 An abnormal anatomical passage between the rectum and the vagina. (MeSH) UMLS:C0034895 perilymph fistula RID:4846 rectovaginal fistula RADLEX: 2020/11/25 RID:4846 RID:4847 perianal fistula RADLEX: 2020/11/25 RID:4847 vesicoenteric fistula RID:4848 enterovesical fistula RADLEX: 2020/11/25 RID:4848 RID:4849 enterocutaneous fistula RADLEX: 2020/11/25 RID:4849 entero-enteric fistula RID:4850 enteroenteric fistula RADLEX: 2020/11/25 RID:4850 An abnormal communication between an artery and a vein. (MeSH) UMLS:C0003855 arterovenous fistula RID:4851 arteriovenous fistula RADLEX: 2020/11/25 RID:4851 perilymph fistula RID:4858 perilymphatic fistula RADLEX: 2020/11/25 RID:4858 Abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia. (MeSH) UMLS:C0040588 RID:4859 tracheoesophageal fistula RADLEX: 2020/11/25 RID:4859 RID:4860 bronchoesophageal fistula RADLEX: 2020/11/25 RID:4860 An abnormal collection of fluid in hollow spaces or between tissues of the body. For example, a pleural effusion is a collection of fluid between the two layers of membrane covering the lungs. (NCI) UMLS:C0013687 RID:4872 effusion RADLEX: 2020/11/25 RID:4872 owl:Thing example to be eventually removed example to be eventually removed failed exploratory term The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job Person:Alan Ruttenberg failed exploratory term metadata complete Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. metadata complete organizational term Term created to ease viewing/sort terms for development purpose, and will not be included in a release organizational term ready for release Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." ready for release metadata incomplete Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. metadata incomplete uncurated Nothing done yet beyond assigning a unique class ID and proposing a preferred term. uncurated pending final vetting All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. pending final vetting Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes. PERSON: Alan Ruttenberg PERSON: Melanie Courtot obsolete_core true placeholder removed placeholder removed terms merged An editor note should explain what were the merged terms and the reason for the merge. terms merged term imported This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use. term imported term split This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created. term split universal Hard to give a definition for. Intuitively a "natural kind" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents. Alan Ruttenberg A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf universal defined class A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal "definitions", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal. Alan Ruttenberg defined class named class expression A named class expression is a logical expression that is given a name. The name can be used in place of the expression. named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions Alan Ruttenberg named class expression to be replaced with external ontology term Terms with this status should eventually replaced with a term from another ontology. Alan Ruttenberg group:OBI to be replaced with external ontology term requires discussion A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. Alan Ruttenberg group:OBI requires discussion Version 2.0, 2024/07/10 A relation that holds between a patient and a clinical finding that consists of clinical, laboratory or molecular evidence, or absence of evidence of disease. PNADO:0001288 Has clinical finding A relation that holds between patient and diagnosis. The value of this relation is the conclusion of the diagnosis process. Example: Patient has pneumococcal pneumonia. PNADO:0001291 Has diagnosis participates in this blood clot participates in this blood coagulation this input material (or this output material) participates in this process this investigator participates in this investigation a relation between a continuant and a process, in which the continuant is somehow involved in the process participates_in participates in RO: 2020/12/18 Alan Ruttenberg Albert Goldfain Anand Kumar Barry Smith Bill Hogan Brian Aevermann Cornelius Rosse Daniel Merico Jie Zheng Lindsay Cowell Richard Scheuermann Sivaram Arabandi Werner Ceusters 2009-08-07 The Ontology for General Medical Science (OGMS) is an ontology of entities involved in a clinical encounter. OGMS includes very general terms that are used across medical disciplines, including: 'disease', 'disorder', 'disease course', 'diagnosis', 'patient', and 'healthcare provider'. OGMS uses the Basic Formal Ontology (BFO) as an upper-level ontology. The scope of OGMS is restricted to humans, but many terms can be applied to a variety of organisms. OGMS provides a formal theory of disease that can be further elaborated by specific disease ontologies. This theory is implemented using OWL-DL and OBO Relation Ontology relations and is available in OWL and OBO formats. OGMS is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX) and the Signs, Symptoms, and Findings Workshop(Milan, Italy). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology. Ontology for General Medical Science http://creativecommons.org/licenses/by/4.0/ The Ontology for General Medical Science (OGMS) is based on the papers Toward an Ontological Treatment of Disease and Diagnosis and On Carcinomas and Other Pathological Entities. The ontology attempts to address some of the issues raised at the Workshop on Ontology of Diseases (Dallas, TX). OGMS was formerly called the clinical phenotype ontology. Terms from OGMS hang from the Basic Formal Ontology. The latest version of OGMS is available at http://purl.obolibrary.org/obo/ogms.owl The OGMS developer site is https://github.com/OGMS/ogms If you are interested in participating in the development of OGMS, please send email to baeverma 2021-08-19 Sylvain Croteau Yasmine Lisa Rebaine Michal Iglewski Sabrina Azzi 2024-07-10 Pneumonia Diagnosis Ontology (PNADO) provides the necessary knowledge to diagnose infective pneumonia. It covers symptoms and clinical signs, clinical history, pathogens, laboratory tests and results, imaging, differential diagnosis and pneumonia complications. 1.2 The following annotation properties are used: oboInOwl:xxxxxx; Examples: - to define CUI: <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">UMLS_CUI:C9999999</oboInOwl:hasDbXref> - database_cross-reference replaced by oboInOwl:hasDbXref - altLabel replaced by oboInOwl:hasSynonym - has_exact_synonym replaced by oboInOwl:hasExactSynonym obo:IAO_xxxxxxx skos:notation (used by SYMP) The following ontologies are reused: - Basic Formal Ontology (BFO) - Ontology for General Medical Science (OGMS) - Symptoms (SYMP) - Relation Ontology (RO) - Human Phenotype Ontology (HP) - Human Disease Ontology (DOID) - Infectious Disease Ontology (IDO) - Logical Observation Identifiers Names and Codes (LOINC) - NCBI organismal classification (NCBITAXON) - Systematized Nomenclature of Medicine Clinical Terms (SNOMEDCT) - Radiology Lexicon (RADLEX) - Computer-Based Patient Record Ontology(CPRO) - Information Artifact Ontology (IAO) The following practice clinical guidelines (CPG) are reused: - https://www.idsociety.org/practice-guideline/community-acquired-pneumonia-cap-in-adults/ - https://www.idsociety.org/practice-guideline/hap_vap/ - https://www.idsociety.org/practice-guideline/community-acquired-pneumonia-cap-in-infants-and-children/ - https://www.nice.org.uk/guidance/qs110/resources/pneumonia-in-adults-pdf-75545291391685 - https://www.ncbi.nlm.nih.gov/books/NBK552669/pdf/Bookshelf_NBK552669.pdf - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094776/ - https://www.atsjournals.org/doi/full/10.1164/rccm.201908-1581ST - https://www.thoracic.org/statements/resources/tb-opi/idsaats-cap.pdf - https://www.thoracic.org/statements/guideline-implementation-tools/diagnosis-and-treatment-of-cap.php - https://www.brit-thoracic.org.uk/quality-improvement/guidelines/pneumonia-adults/ - https://www.atsjournals.org/doi/full/10.1164/rccm.200405-644ST - https://pulmccm.org/infectious-disease-sepsis-review/idsa-guidelines-2016-hap-vap-end-hcap-know-feel-fine/ - https://www.cochrane.org/CD009175/ARI_clinical-symptoms-and-signs-for-the-diagnosis-of-mycoplasma-pneumoniae-in-children-and-adolescents-with-community-acquired-pneumonia - https://www.nice.org.uk/guidance/ng165/resources/covid19-rapid-guideline-managing-suspected-or-confirmed-pneumonia-in-adults-in-the-community-pdf-66141902429125 Version 2.0, 2024/07/10